LOCUS       DADGKS010000001       100706 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.001, whole genome shotgun sequence.
ACCESSION   DADGKS010000001 DADGKS010000000
VERSION     DADGKS010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 100706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 100706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..100706
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.001"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(554..2167)
                     /locus_tag="JXV47_000001"
     CDS             complement(554..2167)
                     /locus_tag="JXV47_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HAX1486081.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2308..3216)
                     /locus_tag="JXV47_000002"
     CDS             complement(2308..3216)
                     /locus_tag="JXV47_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1486082.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            3399..4523
                     /locus_tag="JXV47_000003"
     CDS             3399..4523
                     /locus_tag="JXV47_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAX1486083.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            4548..4727
                     /locus_tag="JXV47_000004"
     CDS             4548..4727
                     /locus_tag="JXV47_000004"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486084.1"
                     /translation="MNKINENTSNTVLPATYSDATSYLTTAAYNYWQTGDFENSYLKE
                     AENFAHKYGVKLTGD"
     gene            4750..5667
                     /locus_tag="JXV47_000005"
     CDS             4750..5667
                     /locus_tag="JXV47_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1486085.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            5660..6493
                     /locus_tag="JXV47_000006"
     CDS             5660..6493
                     /locus_tag="JXV47_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAX1486086.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            6576..7694
                     /locus_tag="JXV47_000007"
     CDS             6576..7694
                     /locus_tag="JXV47_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAX1486087.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            7688..9586
                     /locus_tag="JXV47_000008"
     CDS             7688..9586
                     /locus_tag="JXV47_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HAX1486088.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            9580..10803
                     /locus_tag="JXV47_000009"
     CDS             9580..10803
                     /locus_tag="JXV47_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronyl hydrolase"
                     /protein_id="HAX1486089.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(10889..12823)
                     /locus_tag="JXV47_000010"
     CDS             complement(10889..12823)
                     /locus_tag="JXV47_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAX1486090.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            13049..13705
                     /locus_tag="JXV47_000011"
     CDS             13049..13705
                     /locus_tag="JXV47_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAX1486091.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(13779..14132)
                     /locus_tag="JXV47_000012"
     CDS             complement(13779..14132)
                     /locus_tag="JXV47_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAX1486092.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            14324..15253
                     /locus_tag="JXV47_000013"
     CDS             14324..15253
                     /locus_tag="JXV47_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HAX1486093.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            15264..16100
                     /locus_tag="JXV47_000014"
     CDS             15264..16100
                     /locus_tag="JXV47_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HAX1486094.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            16348..17124
                     /locus_tag="JXV47_000015"
     CDS             16348..17124
                     /locus_tag="JXV47_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1486095.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            17300..18043
                     /locus_tag="JXV47_000016"
     CDS             17300..18043
                     /locus_tag="JXV47_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1486096.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            18036..19616
                     /locus_tag="JXV47_000017"
     CDS             18036..19616
                     /locus_tag="JXV47_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HAX1486097.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(19867..20346)
                     /locus_tag="JXV47_000018"
     CDS             complement(19867..20346)
                     /locus_tag="JXV47_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter"
                     /protein_id="HAX1486098.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(20362..21114)
                     /locus_tag="JXV47_000019"
     CDS             complement(20362..21114)
                     /locus_tag="JXV47_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HAX1486099.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNNLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            21231..21301
                     /locus_tag="JXV47_000020"
     tRNA            21231..21301
                     /locus_tag="JXV47_000020"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21263..21265,aa:Gly,seq:ccc)
     gene            21662..22387
                     /locus_tag="JXV47_000021"
     CDS             21662..22387
                     /locus_tag="JXV47_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HAX1486100.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            22642..22908
                     /locus_tag="JXV47_000022"
     CDS             22642..22908
                     /locus_tag="JXV47_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HAX1486101.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPSYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            22905..23336
                     /gene="ruvX"
                     /locus_tag="JXV47_000023"
     CDS             22905..23336
                     /gene="ruvX"
                     /locus_tag="JXV47_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HAX1486102.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            23361..23666
                     /locus_tag="JXV47_000024"
     CDS             23361..23666
                     /locus_tag="JXV47_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HAX1486103.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(23747..24892)
                     /locus_tag="JXV47_000025"
     CDS             complement(23747..24892)
                     /locus_tag="JXV47_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAX1486104.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(24953..25600)
                     /locus_tag="JXV47_000026"
     CDS             complement(24953..25600)
                     /locus_tag="JXV47_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1486105.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            25794..26087
                     /locus_tag="JXV47_000027"
     CDS             25794..26087
                     /locus_tag="JXV47_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486106.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            26131..26442
                     /locus_tag="JXV47_000028"
     CDS             26131..26442
                     /locus_tag="JXV47_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486107.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            26439..27063
                     /locus_tag="JXV47_000029"
                     /pseudo
     CDS             26439..27063
                     /locus_tag="JXV47_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            27363..27725
                     /locus_tag="JXV47_000030"
     CDS             27363..27725
                     /locus_tag="JXV47_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486108.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            27762..28610
                     /locus_tag="JXV47_000031"
     CDS             27762..28610
                     /locus_tag="JXV47_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein"
                     /protein_id="HAX1486109.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            28600..30075
                     /locus_tag="JXV47_000032"
     CDS             28600..30075
                     /locus_tag="JXV47_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HAX1486110.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            30341..30748
                     /locus_tag="JXV47_000033"
     CDS             30341..30748
                     /locus_tag="JXV47_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HAX1486111.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            30751..30966
                     /locus_tag="JXV47_000034"
     CDS             30751..30966
                     /locus_tag="JXV47_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486112.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            30970..31350
                     /locus_tag="JXV47_000035"
     CDS             30970..31350
                     /locus_tag="JXV47_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAX1486113.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            31484..31639
                     /locus_tag="JXV47_000036"
     CDS             31484..31639
                     /locus_tag="JXV47_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HAX1486114.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            31708..32181
                     /locus_tag="JXV47_000037"
     CDS             31708..32181
                     /locus_tag="JXV47_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HAX1486115.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            32178..33872
                     /locus_tag="JXV47_000038"
     CDS             32178..33872
                     /locus_tag="JXV47_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAX1486116.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            33838..34023
                     /locus_tag="JXV47_000039"
     CDS             33838..34023
                     /locus_tag="JXV47_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486117.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            34027..35202
                     /locus_tag="JXV47_000040"
     CDS             34027..35202
                     /locus_tag="JXV47_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAX1486118.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            35195..36718
                     /locus_tag="JXV47_000041"
     CDS             35195..36718
                     /locus_tag="JXV47_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAX1486119.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            36774..37058
                     /locus_tag="JXV47_000042"
     CDS             36774..37058
                     /locus_tag="JXV47_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HAX1486120.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            37045..37380
                     /locus_tag="JXV47_000043"
     CDS             37045..37380
                     /locus_tag="JXV47_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAX1486121.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            37675..38301
                     /locus_tag="JXV47_000044"
     CDS             37675..38301
                     /locus_tag="JXV47_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486122.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            39043..39879
                     /locus_tag="JXV47_000045"
     CDS             39043..39879
                     /locus_tag="JXV47_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HAX1486123.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLINLYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            39943..40374
                     /locus_tag="JXV47_000046"
     CDS             39943..40374
                     /locus_tag="JXV47_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1486124.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(40436..41758)
                     /locus_tag="JXV47_000047"
     CDS             complement(40436..41758)
                     /locus_tag="JXV47_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HAX1486125.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(41912..43552)
                     /locus_tag="JXV47_000048"
     CDS             complement(41912..43552)
                     /locus_tag="JXV47_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HAX1486126.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            43885..44355
                     /locus_tag="JXV47_000049"
     CDS             43885..44355
                     /locus_tag="JXV47_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HAX1486127.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            44577..45680
                     /locus_tag="JXV47_000050"
     CDS             44577..45680
                     /locus_tag="JXV47_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAX1486128.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLKDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            45964..46644
                     /locus_tag="JXV47_000051"
     CDS             45964..46644
                     /locus_tag="JXV47_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAX1486129.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            46734..47768
                     /locus_tag="JXV47_000052"
     CDS             46734..47768
                     /locus_tag="JXV47_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAX1486130.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            47782..48117
                     /locus_tag="JXV47_000053"
     CDS             47782..48117
                     /locus_tag="JXV47_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486131.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            48101..50581
                     /locus_tag="JXV47_000054"
     CDS             48101..50581
                     /locus_tag="JXV47_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486132.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWKLTAGPTS"
     gene            50637..52196
                     /locus_tag="JXV47_000055"
     CDS             50637..52196
                     /locus_tag="JXV47_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1486133.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            52193..53557
                     /locus_tag="JXV47_000056"
     CDS             52193..53557
                     /locus_tag="JXV47_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAX1486134.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            53728..54798
                     /locus_tag="JXV47_000057"
     CDS             53728..54798
                     /locus_tag="JXV47_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1486135.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            54813..55481
                     /locus_tag="JXV47_000058"
     CDS             54813..55481
                     /locus_tag="JXV47_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1486136.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            55501..56079
                     /locus_tag="JXV47_000059"
     CDS             55501..56079
                     /locus_tag="JXV47_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAX1486137.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            56480..57391
                     /locus_tag="JXV47_000060"
     CDS             56480..57391
                     /locus_tag="JXV47_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAX1486138.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(57479..58396)
                     /locus_tag="JXV47_000061"
     CDS             complement(57479..58396)
                     /locus_tag="JXV47_000061"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HAX1486139.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            58598..59035
                     /gene="zapA"
                     /locus_tag="JXV47_000062"
     CDS             58598..59035
                     /gene="zapA"
                     /locus_tag="JXV47_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HAX1486140.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            59094..59642
                     /locus_tag="JXV47_000063"
     CDS             59094..59642
                     /locus_tag="JXV47_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HAX1486141.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            59757..62117
                     /locus_tag="JXV47_000064"
     CDS             59757..62117
                     /locus_tag="JXV47_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HAX1486142.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEEQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLYDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            62204..62518
                     /gene="trxA"
                     /locus_tag="JXV47_000065"
     CDS             62204..62518
                     /gene="trxA"
                     /locus_tag="JXV47_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HAX1486143.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            62700..64478
                     /gene="uvrC"
                     /locus_tag="JXV47_000066"
     CDS             62700..64478
                     /gene="uvrC"
                     /locus_tag="JXV47_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HAX1486144.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            64623..65522
                     /locus_tag="JXV47_000067"
     CDS             64623..65522
                     /locus_tag="JXV47_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1486145.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            65515..66777
                     /locus_tag="JXV47_000068"
     CDS             65515..66777
                     /locus_tag="JXV47_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1486146.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            66938..68836
                     /locus_tag="JXV47_000069"
     CDS             66938..68836
                     /locus_tag="JXV47_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HAX1486147.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(69166..69885)
                     /locus_tag="JXV47_000070"
     CDS             complement(69166..69885)
                     /locus_tag="JXV47_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HAX1486148.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            70222..70554
                     /locus_tag="JXV47_000071"
     CDS             70222..70554
                     /locus_tag="JXV47_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486149.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            70541..72544
                     /locus_tag="JXV47_000072"
     CDS             70541..72544
                     /locus_tag="JXV47_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HAX1486150.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            72563..73033
                     /locus_tag="JXV47_000073"
     CDS             72563..73033
                     /locus_tag="JXV47_000073"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HAX1486151.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            73054..73638
                     /locus_tag="JXV47_000074"
     CDS             73054..73638
                     /locus_tag="JXV47_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HAX1486152.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            73653..74639
                     /locus_tag="JXV47_000075"
     CDS             73653..74639
                     /locus_tag="JXV47_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HAX1486153.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            74629..74940
                     /locus_tag="JXV47_000076"
     CDS             74629..74940
                     /locus_tag="JXV47_000076"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HAX1486154.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            74962..76743
                     /locus_tag="JXV47_000077"
     CDS             74962..76743
                     /locus_tag="JXV47_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HAX1486155.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            76736..78112
                     /locus_tag="JXV47_000078"
     CDS             76736..78112
                     /locus_tag="JXV47_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HAX1486156.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            78119..78754
                     /locus_tag="JXV47_000079"
     CDS             78119..78754
                     /locus_tag="JXV47_000079"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HAX1486157.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            78784..80139
                     /locus_tag="JXV47_000080"
     CDS             78784..80139
                     /locus_tag="JXV47_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HAX1486158.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(80331..81725)
                     /locus_tag="JXV47_000081"
     CDS             complement(80331..81725)
                     /locus_tag="JXV47_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAX1486159.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRTQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            81817..82788
                     /locus_tag="JXV47_000082"
     CDS             81817..82788
                     /locus_tag="JXV47_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HAX1486160.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            82785..83567
                     /locus_tag="JXV47_000083"
     CDS             82785..83567
                     /locus_tag="JXV47_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HAX1486161.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(83736..84107)
                     /locus_tag="JXV47_000084"
     CDS             complement(83736..84107)
                     /locus_tag="JXV47_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAX1486162.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            84241..84684
                     /locus_tag="JXV47_000085"
     CDS             84241..84684
                     /locus_tag="JXV47_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAX1486163.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(84727..85536)
                     /gene="yidA"
                     /locus_tag="JXV47_000086"
     CDS             complement(84727..85536)
                     /gene="yidA"
                     /locus_tag="JXV47_000086"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HAX1486164.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(85555..86922)
                     /locus_tag="JXV47_000087"
     CDS             complement(85555..86922)
                     /locus_tag="JXV47_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAX1486165.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(86906..87736)
                     /locus_tag="JXV47_000088"
     CDS             complement(86906..87736)
                     /locus_tag="JXV47_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HAX1486166.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            87899..88336
                     /locus_tag="JXV47_000089"
     CDS             87899..88336
                     /locus_tag="JXV47_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HAX1486167.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            88412..89032
                     /locus_tag="JXV47_000090"
     CDS             88412..89032
                     /locus_tag="JXV47_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HAX1486168.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            89221..89727
                     /locus_tag="JXV47_000091"
     CDS             89221..89727
                     /locus_tag="JXV47_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HAX1486169.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            89744..90643
                     /locus_tag="JXV47_000092"
     CDS             89744..90643
                     /locus_tag="JXV47_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HAX1486170.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            90730..91614
                     /locus_tag="JXV47_000093"
     CDS             90730..91614
                     /locus_tag="JXV47_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAX1486171.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(91806..91877)
                     /locus_tag="JXV47_000094"
     tRNA            complement(91806..91877)
                     /locus_tag="JXV47_000094"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(91842..91844),aa:Arg,seq:ccg)
     gene            91937..93271
                     /gene="rpoN"
                     /locus_tag="JXV47_000095"
     CDS             91937..93271
                     /gene="rpoN"
                     /locus_tag="JXV47_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HAX1486172.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            93474..94511
                     /locus_tag="JXV47_000096"
     CDS             93474..94511
                     /locus_tag="JXV47_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SorC family transcriptional regulator"
                     /protein_id="HAX1486173.1"
                     /translation="MLDEIKMIESVAPDIIEVLQERYKILRNIYWMQPIGRRSLSESM
                     GITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSLENFMDQLLGTHQTEQQLA
                     EYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEGENIIAVMGGTTMAVVAEQ
                     LSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKANGNHRALYVPEQLSLATYN
                     SLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEKELVMLKQANAVAESFGYF
                     FNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAIRAYMKNAPKQTWLITDEA
                     AANEILKGVTL"
     gene            94552..95553
                     /gene="gap"
                     /locus_tag="JXV47_000097"
     CDS             94552..95553
                     /gene="gap"
                     /locus_tag="JXV47_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAX1486174.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            95663..96853
                     /locus_tag="JXV47_000098"
     CDS             95663..96853
                     /locus_tag="JXV47_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HAX1486175.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            96957..97712
                     /locus_tag="JXV47_000099"
     CDS             96957..97712
                     /locus_tag="JXV47_000099"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HAX1486176.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            97828..99126
                     /gene="eno"
                     /locus_tag="JXV47_000100"
     CDS             97828..99126
                     /gene="eno"
                     /locus_tag="JXV47_000100"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HAX1486177.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            99525..100664
                     /locus_tag="JXV47_000101"
     CDS             99525..100664
                     /locus_tag="JXV47_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HAX1486178.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT        33406 a        17204 c        20781 g        29315 t
ORIGIN      
        1 tgttaaataa ataggaacaa aaaaattaaa ttatttaata cacacattag ggatcattca
       61 ttgaaggatt agaagacaac gaggatggcg aaaaatatga ttacaataga aaagtcgttc
      121 taaaccaatc agttcctagt atcacacaac gcaagccagt cgatttggtg agattagagg
      181 agtgaaagca aactttatta tataagaaaa aatattcgaa agggatgcta gtttaggtac
      241 tagtgctgat agattaatat gatgcctcgt aatattaggc gtagttactc tagagacatc
      301 actatggact atgatttgtc tcagagtcac aacatgtttt tttatgaaaa gaaacagcta
      361 aaataattaa attgcgcaat gtttaaactt tcttaaacta taacctaata aatgtgaaga
      421 aataatgcac aatttcttca catttatctt ctattctata tacataccaa ccaacaaccc
      481 tatatacttt ttcattttta ctcctcaagt aaaaataact cctagaccgc ggctacccac
      541 cgcggtcgtt tttttattct tcaatcaaaa tcgctttgat acccaaacct gccaagattc
      601 gggcagaagt ataagtattc aatcctcttc tgaaagtaat gtaaactttt ttatcttttg
      661 ggatttcatt gattcgatct cgtaactcat tcattggaat attttttgtt gccgagatac
      721 tgccagaagg tgctttatta ggttcacgta tatctaaaaa gaacgcttct ttcaaatcgt
      781 tttcgggtat atcacttgct ttgatcgttt ctacgatatt cgtcatttga ttgattgcga
      841 cataaccagc tatattcaac gggtcacggg tagtagaata cggtggagag taaggcaact
      901 ccaaatcagg caaatcaaag actgtcaagt ttccggtgat tgctacagaa agttctccca
      961 tccgtttatc gacacctttt tctccaaatg cttgtccacc taaaatacga ccgctatctg
     1021 catcaaaaat cagctttaga tttaatcttg tagcttctgg atagaaatag gcatggtcaa
     1081 agggagtgat aaaaacagtt ttataatttg ttatgcctga tgcttttaat tcatgttctg
     1141 tcattcccgc ataacttgct gtatgatcaa agatttttgc gacacctgca ccaatatatc
     1201 cgcgatagcg cataggcgta ccatttaaaa tatctgccag catatgtcct tgacgattgg
     1261 ccgcactgga aagcatactt tggatcggct gaccagtcac tacactagtc gtttcgataa
     1321 tatcgccaat cgcatagatg tccggcagat tggtttgtaa ctggtcatca acaatgatct
     1381 gacctgtatc tgataattgt atgccggttg ctttcaccac ttcattcttc ggagaaacac
     1441 caacagcaaa aattagcata tcagcagaaa ggacggagcc atctgataat actatttctc
     1501 gacctttatc acggatctca gtaactcttg tttctaaatg aacggctaat ccttctttca
     1561 gcaatttgtc ataaactaaa ttagcaattt ctggatcata agggaaagcg acttgtggca
     1621 attgatcgat taaagtcacg tctaagccgc gatgcttgaa attctcagct aattccagac
     1681 ccataacacc tgcaccaaga atgacgacat gttgtggatt tttttcttca aggaacgatt
     1741 tgattcgatc cgcatccgtc acactacgga ggacaaagcc gttttctgct tcaaaaactc
     1801 cgggaatatc cggataatct ggtctagcac cagaagagat gatcaactta tcgtaatctg
     1861 tttttatttc ttcatttgtg gataggtctt taactgttaa tcgcttagta gaaggatcga
     1921 ttgctgttac ttcgtgttta gtaaagacat cgatgttgtt ttttgttttc aatatttctg
     1981 gtgtacgttc gatcagcgag tcacggtcag tgatcacacc tcctaaataa taaggcaaag
     2041 cacaacttgc ataagaaata ttttctccgc gttcatagat aatgatttcg tgcgcttcat
     2101 tcaatcgacg gaaacgagtg gcaaatgaag gaccgccagc tacaccgcca atgacaacaa
     2161 ctttcataaa aacatctcct tttctacgtt gatcgtacta tgttatggta aaaaacagca
     2221 aataattgtg ccggaaaatt attgtttatt ttgaatagac agaaaatata gagaaataat
     2281 ttgtggataa aacctaaaaa tttttttcta ttttaaggat agataatact ttgaagggga
     2341 taaccctgta tattttttaa aagctgaaga aaaatgatgg atcgaatgaa atcctaatat
     2401 atctgcaatt tctgtatagg ttaattcatt ttctagcacg agacgttttg ctttttccat
     2461 ttttagttct ttaaaatagc taataacact ttttccattc acttttctaa aatgtttttt
     2521 taagctggct ggactgataa aaaaaatttg ggctaattgt tcaagcaaaa aattttctga
     2581 aagatgttct tctaaatatc gtatgattgg atcaactaat tcatctgaat aaagaatatg
     2641 ctttttttta ggaatgactt tctcatttga aggtattgtc aataaagcaa gttcctgttg
     2701 ataatgcctt ggtaaggaag acaattgaat tttttgcaga caataagtaa ctaataagga
     2761 aagcaaatga atgctcatct gttggcatag tatgaaaaaa gaattgattt cctgatcata
     2821 ggaaatagct ggcttactat gttttagata atcaattttg aactgttcat ttttcagaaa
     2881 agtaatgata gatgttattt cttgatctat agaaaaagat tgtcccgtaa tatgtgctaa
     2941 taattgctca tcaaaataaa actggataat gataaaagtt tgtgtttcct tttgagtaga
     3001 aaagatttgg acttcttgct gtttatcaat gaataaaagg gaaggattat ctagttctat
     3061 agatttatgt gcaaattcag catataaatt agcgctttca tttattagta gtcgaaaata
     3121 gggagcagca gataaatgaa gatgggtatc tatggaatag gttagtgttt ttttgacaag
     3181 attggaggat tggttgtttg ttaacaaaag aaccactttc ctttctcttt ttatataaaa
     3241 agctttctat ttataattaa tgactattat aacaaaaatg aaaagccaaa acgacaagta
     3301 aaatattttt ttatataaat atttgtgtta ctaattccgt taatatacat aagtgaaagc
     3361 gttttatata agaacttgaa aagaaagaag ggatagacat gaaaaaaaga tacaaattgg
     3421 tgatagcttt gctaaacatt accctattat tcagcttaag tgcatgtgga aaaactaacg
     3481 aagaagtaac agcaaacatc gcagatccaa tgataaaaaa agccactaca ttagaagtat
     3541 atgtcgcaaa cggcaaactg acaaactatg ttgaaaatgc tgcaaaaatc tataaccgca
     3601 aaactggagc aaatattgac ttaaaaattg tgaatgtagc ttcgggaaca gcaacagtac
     3661 aaatgatcac cccaaaattg gtaacacacg aagatatgcc ggatattatc tccatggcag
     3721 acacttcagc agcaggtgtg ctggaaaaat ttcaagatgc tttttatagt gctgatgaat
     3781 atggatttta tgacaaatat ggcgatcagt tttatgatca aaaattgaat attttgcgtc
     3841 aacaaacgag taatgaaacg attattcctt gggctagtga ttttacccca gcactttgtt
     3901 attatcaacc aaaaaaattt gctgaaatag gtgtagattt tgaagaaatc agttcttggg
     3961 aagaatatat ccaggtggca aaagcattaa aagaaaaaac tggtagtttt ggaattgcct
     4021 tgccagaatc tggggaccaa gaattgttta tcaacatgct agcccagcag aatcaatctt
     4081 tgcttgatga agaaggaaat atccgtctga atactaaaga agcgaaacat gctgcaaagt
     4141 taatcaaaga aatgatcgac tcagatattg tacatttcta cggtgcacaa gatgctgaga
     4201 aagcatttca agaatctgca atgtttgttg ctggcggctg gtatgctacg aatatgtctt
     4261 tgaattttcc tgatgcatct gacaaatggc gcatggctcc actgattcct ttttcaaaag
     4321 aaaatccagg aaaaggtgca gtatcaggag gatcaagttt ttatgtccct aaagatgcaa
     4381 aaaatccaca agtggcacaa caatttctta catttatgct gacagatgaa gaatgcttag
     4441 ccaacgcact ggagctgggc gtggctacat ctaactcatt ggcctatcaa acagaagcag
     4501 ctgagaaaaa gtttgactac taaggaggac aaaaatacta tgaactattg aataaaatca
     4561 atgaaaatac atcaaatact gttttaccag ccacttattc agatgctacg tcttatttga
     4621 ctaccgctgc atataactat tggcaaacag gtgattttga aaattcatat ctaaaagaag
     4681 cagaaaattt tgctcataag tacggcgtaa aattaactgg tgattaaaaa atattaggag
     4741 gacttaacga tgatgcaatc ttcgttacca agcaagacaa taaagaacag caagaaaaaa
     4801 gcaacagata cgtctcataa aaaaagtgct tatggattgg tcacaccttt tgttattttc
     4861 tttattgtga cgattttgat tcccatcatt atctcgtttg cttttagttt tatgaaaatt
     4921 ggctactcat ttgaatttgt tggatttgac aattatctag ctatcttccg agatccattg
     4981 tttattaaat cttacacgaa tgttttgatt atcatggcag gatcaattcc aataacgatg
     5041 ctattagcta tttactttgc tgttttattg aattcagcac agttaaaagg aaaaggattt
     5101 tttagaactg tctattatat tccaaccatt acatcaacgg tggctgtagc ttccgtattc
     5161 atgacttttt tcaatccgac tgggttattc aatggatttt tgaatgcgct aggaattaac
     5221 ggtgtacagt ggttaacaaa tcctttttgg atacgaatat caatgatcat cacgatgatt
     5281 tggcttagtg taggatataa cactatttta tttttagctg gtcttcaagg gatttctaaa
     5341 gagatatacg aaagtgctga aatagatgga gcatcgaaat ttcggcaatt ctttttatta
     5401 acgatcccca tgctaaagcc aatcatttta atggccacag ttttagccac tatcaatggc
     5461 ttgggtaatt tcaatatccc aaatatattc tttgggactt ccaatggacc agaaaattca
     5521 gctttggtcg taggagtcaa tttatataaa acaagttttg aaatggttga ttttggaaaa
     5581 gcctctgcta ttgcctggac gatggtgttt gtatctgtta tattatcggc tattcaattt
     5641 aaattcggag gtgataaaaa tgactaaaca aaagatacaa agcagaattt ttacgtacgt
     5701 cattattgtg tttggtgcct taatattttt gatgccatat ttatatatga ttgtagcttc
     5761 aacgcaaagt aatcaagaaa ttttaagtgg cggaatcaat ttcaagtttg gggatatgct
     5821 attaaaaaac tggcaagcca tcatggcgag atataattat cccttgatta tttggaattc
     5881 gattgttatt gctgtaatca gtacagtttt agctacagcc agttctacaa tggcgggtta
     5941 tgcattagca aagtatcgtt ttatggggaa taaactgttg ttcaatacag ttatgctatc
     6001 taggatggtg ccttttttta ccacattgat tcctttattt tacattatga gtcgtttagg
     6061 attatcgaat acttatgcag gtgtgatcat cccttcgatt gccagtacaa cttcagtgtt
     6121 tatgatgcga caatatagca gtcaatttcc tacagcactg atggaggctg ccagaatcga
     6181 tggtgccaat gagtgggtga tttttacgaa aatcgctgta ccgattttat cacctacgat
     6241 tattactagt ggtttactta tctttatggg aagttggaat caatatctat ttccattagt
     6301 catgctttca gataaagata aatatacggt tcccttaatt atcaaaaata tgacggtttc
     6361 tagtacaggt gagccaatta attatggcgc aattatgcta attttagcaa cttcagtgat
     6421 cccaatggtc ttgatttatg tgtgggcgca gtctaaattt aaggagaatg acattggagc
     6481 tgcaaataag taaaaaaaat aacgaatgtt aaccatctag ttcgttctag gagcaactcc
     6541 acattcataa aaattaaaag aatggcggga tatccatgaa tgaacagacg aaggaatggt
     6601 caagaaaaat tttgaatgta gcttctgaaa agatagatgc ggaattagac agaatgggga
     6661 ataaaattcc atatatttct tacaacggaa aatatacaga cgtaataaag gacagaggaa
     6721 tcgactggtg gaccaatggt ttttggagtg gtattttatg gcagctcttt cacaagacaa
     6781 aacgagaaaa gttcaaagag gcagcaatac aacaagaaca attattagaa tctgccctgt
     6841 accatttttc agacgttcat catgatgtag gttttttatt cttaccatcg gctattgcac
     6901 attatcaaca gtctcaaaac aaacatagtc gacaactagg gttacatgca gctacggtac
     6961 ttgctggacg ctataatatt tcagggaact atttagtagc atggaatgac cataaacctg
     7021 gttggatgat tattgatagt atgatgaatt taccattact gtattgggct tcgagggaaa
     7081 ctggtgatcc gaggttctct aaaattgctc ggcagcatgc agatacaaca gctaagtatc
     7141 tagtgaggaa agatggatca accgggcata tcgcagaatt tgatgcagaa tcagggaaat
     7201 atattcggtt acttggcggg caaggataca atgagaattc ttgttggagc agaggaaatg
     7261 catgggcttt atatggattc gcgttaagtt atcgttacac aaaaaatccg tactatctag
     7321 ctatagcaga aaagatagca gtaaatttta ttcagaaaat cgaaaaaact ggttatattc
     7381 ctctcattga ttttgctgta aaagattcga atattgatac cagtgctgga gtatgcgctg
     7441 catgcggtct tctggaatta gcaggatatg tttcctctgt acgatcaaaa atgtatcatg
     7501 aagctgctat caatatactc caaaagacag aaaagcacta tgcaaattgg aatatggatg
     7561 aagatgggat cattggaggc ggagcagaag cataccatag agaactgact tataatgtgc
     7621 cactgatcta ttctgattat ttttttattg aaggcttact tcgattagaa cagtcggaat
     7681 tagctatttg gtagtaaaaa gaggagaaaa tacaatgaaa catccagtac cactattaag
     7741 gaccagacag gattactttg acttatttaa aaagataaat caaccactcc agccgtttta
     7801 tcgagcaagt ggcgcacaaa ttgattatat acatcaaggg gtaggatatg gaaataaaat
     7861 tgcaggaatg gaaggattct ctcgggtttt atggggagcg gggcccgcaa ttgaccaatt
     7921 agatgaacga tggttgaaat taattctatc aggaataaaa gctggaacag atccttccca
     7981 tcccgattat tggggagaaa tacatgaaag agaccagcgt atggtagaaa tgcccgcaat
     8041 gttattagcg ttatatcatc atgaacaatt attatggaaa aaattagata caggagaaaa
     8101 aagccagatt attcattggt tctcgcaaat ttttgaatat gaatgtgcag atggtaattg
     8161 gcaatttttt aagataattg tcggaacaat tatccaaaaa tttggttatc cagttaaaga
     8221 atcagcactg aaagaagcat ttgataatat agaaaattgt tatcttcaaa atggctggta
     8281 tcgagacagt tcaagaggtc gccaagatta ttataatcct tttgcatttc attattatgg
     8341 tttgatttat agcgtactag aaccagaaaa gcccattagc cagatatata agaaccgagc
     8401 tattgatttt tctagagact atattcattt ttttgcggaa gatggtgcaa atgtgccttt
     8461 tggtcgaagc atgatttatc gttttgcagt ttcaagcttt tggtcagcta tgttgtgggc
     8521 cgatcttttg ccttttaaat taggtgaaat caaggggtta gtcaatcgga atataagatg
     8581 gtggatgcaa aaagaaatat ttgatgaaaa aggtatcctg aatattggtt atacctaccc
     8641 tcaattgaca ttgactgaac cctataatag tacgttatct ccattatggc tgaataagat
     8701 ttttttattg ttggcgctac ctgaagacca tgagtattgg acggctaaag aaatgcctat
     8761 gcctattcgt gaaggaacta aacttctttc agaagccaat ttgctcatac aacatgataa
     8821 tggacataca ttttttttga atgcgggaca attagggcca aatttccata cattgaccaa
     8881 tgaaaaatat ttaaaatttg cttattctag tcaatttggt ttttcgatac cgcgagcgaa
     8941 tcaattgaaa gcagaaatgg caatggattc aatgctaggg attcagcgag cggacacata
     9001 tatcacgacc agttttaaga atgagagcat caaaacctat ggacagttca tcgttcgaaa
     9061 taatgtacga gacattgtat gtaagaaaga ggtacttgcc tctacatggg aacctacttt
     9121 acaggcaaaa atcagaactt ggcttattcc ttttgaaggc tggcagattc gcgtacacaa
     9181 agtagaatta gatacagaat atgttctata tgagacaggg tttgctattg aatgttctcc
     9241 tgagaaagaa ggaataatca tagaagaaga caaggaaaac tatagggtga gtgaagctgg
     9301 cttttcaggt attatctgtt taagtgacga tactattaaa cgaaaatcca cagctattat
     9361 gggtttgccc aatacaaact tgatgacatg ggaaaacact tttattcctg gattagaggg
     9421 tacatttgga aaaggaaccc attggctcgg aacaggagtg gttgctcatc aagatcggga
     9481 ttatagttta gaagtatgga acaatcgtcc caaaattgat tttgatggga caaccgggct
     9541 aactatccaa aataaaaaca ataaaaaaag actaaaatta tgctaaaggc tggtggggaa
     9601 atgcttgata aagtgatgtt tgaagagata atacatccag aaaaatggat aaatgaatgt
     9661 tataaagaat taatggaaaa agaatggaat aatgagatcg agcgttgtcg cagacacacg
     9721 gagaggttaa tcaaacgtat cagtaacagt cagtatcaat tcccaagcga gtgtcctata
     9781 aaaggacgtt atccattaag agacaatatt ggttggacag aaggattttg gacaggaatt
     9841 aattggttgt tatttgagaa gacgggtgat cctttatttc aacaaacagc tgaaaaagca
     9901 gatatagatt ttatccacag gattgactgt caaattatca ctaatcatca cgatcttggt
     9961 tttttgtatt ctttatcaac cgtagcagat tataaaataa cgggaaatcg aaaaatgaag
    10021 gaagcttcaa ttgatgctgc agaaacatta cttcagcgtt tttgggagaa ggcaggagtt
    10081 atacaagctt ggggagatcc tagtgatcct tcacaacaag gtagaatgat catggattgt
    10141 tgcatgaatc ttccattatt gtattgggcg agtgaagaaa ctggaaatca aaaatataaa
    10201 aaagctgctc aggctcatat tcaaaatgca gcagattatt tagtaagaga agatggttca
    10261 acttatcata cattttatat ggatgtcaaa gatggaaaac caagatatgg aagtacgcat
    10321 caaggttata gtgataattc ctgttgggct agaggccaag catgggggat ttacggtttt
    10381 gcattaagtt atcgttattt gaaagaacaa aaatattttg atttaagcaa aatattagcc
    10441 aattatttta tgaatcggtt gccagaagat accatttgtt attgggattt gatctttgat
    10501 gattctagca gagaagaaaa agatacatct agtatggtga tcatggtttg tggattatta
    10561 gaattaatag aatcaggtct attagacaaa acagaaaaga acttatacca gtctgctgtt
    10621 tggaaaatta tgcgacaatt gaaagaaaga tatgctacaa cggaagaaga agatggcttt
    10681 ttaacacagt ctgtttataa taagcccaaa aataatgggg taaatacacc ttgtatttgg
    10741 ggtgattact attatttaga agctttagtg agaatgacta gtaattggtc ttcttattgg
    10801 tgaaaaaggt aaatatggaa tttttgtttg ataaaataaa aaaagaaaaa ccaaaacagc
    10861 atgaatggtt tctgttttgg ttttttcgtt aattttcata ttcttctaat tccaagctta
    10921 gttcttccca ttccgtcaat tttgtttctt gatcttgtct agcagcttct aaatcttggt
    10981 tcagctcatt gagttttacg tgatcttcca ggttttctgg cgcgaccatt tcttgttcca
    11041 actgatcgat ccattcatcg atccgcgcca tttcttcttc aacctgagta atttttcgtt
    11101 gaaggctacg gataagcttt tgctgttctt tgctttggta ataatcagat ttgttcgtgg
    11161 gagcaggagc agattctggc tcatcttgtg ccaacaattc ggcgatttct tcttcttcct
    11221 gctttttctc taaataataa tcatagtctc ctagatagac tttgctgcca ttttcagaga
    11281 gttcgacgac ttttgtcgcg atccgattga tgaaatatcg gtcatgggaa acaaaaagca
    11341 gtgtgccgtc ataatcgatc aatgcatttt ctaatacttc tttgttgtca atatctaaat
    11401 ggtttgttgg ttcatccaaa atcaaaaaat tttctttgtt catcgctaac ttggctaaag
    11461 caacccgtgc tttttcaccg ccacttagca gagggattgg tttttctaca tcttcgccag
    11521 aaaataagaa agcacctaaa gcacttcgga tctctttttc tggagtggta ggatgctcat
    11581 cccacaattc tgctaggatc gtcttgtttg tatgcagatc agcttgacct tgatcgtaat
    11641 agccgatggt gacatttgtc cctagcgttt cttttccacg gataaaaggg atctggtgaa
    11701 tgattgattt cagcaacgtc gatttcccga taccattcgg acctactaga gcaatcgctt
    11761 cttgacgacg gatatctaga ttgattggtt cagataaggt gacattatca tatccgatag
    11821 cggcatcttc gatttgcaag actacatttc cagaaggctt ttctatactg aatagaaagt
    11881 ttgcttgttt ttcatcccct tgaggacgat ccagccggtc cattttttct aatgtctttc
    11941 tgcggctttg cgctcgtttt gtggtagagg cgcgaacaag gttccgagca acgaagtctt
    12001 ctaatttatg gatttctgtt tgctgctttt cataagcctt ccattcactt gctaactgtt
    12061 ctgctttcaa atctagatat ttcgaatagt tacctttgta atggcgcatt tttcttctgc
    12121 ttaattcata gacttcattg actactttat ctaaaaaata acggtcatgg gaaacaatca
    12181 ataatgcacc agtatagctt tgcagataat tctcaagcca ggaaagtgtc tcgatatcta
    12241 aatggttcgt tggttcatct agaatcaaaa tgtcagggtg ttgcaaaagc atgcgagcta
    12301 aagctaaacg tgtgcgctgt ccgcctgata aagtatcgat tttctgatca taaaatgaag
    12361 aatcgaattt aaacccatgc aatacggaac gaatttcatt ttcataacca tagccgtttc
    12421 gatctgaaaa atcgtgttgc agccggtcgt attcttttaa ataagaacta taagcaggtg
    12481 tgtctggcgt accttcgcta atgaaaatct ctagctcgcg catccgctct tccatttgtc
    12541 taacttgttc aaaagctttc agcatctcgt tccaaactgt ttcattggaa tcaagtcctg
    12601 tgtcctgagc gaggtatccg agagtcgctg ttttattttt agcgatcttt ccttcatcag
    12661 gtgcttcaat tccagcaatg atctttaata aagtcgattt tccagcgcca tttctgccaa
    12721 ctaaagcgac acgagcgcct gtactgattt ctaaatgtat gttttcaaat aagacttctg
    12781 caccaaaatg gcgagcaatc tgattggctt gtaataatat catggaatcc tcttttctac
    12841 tttgtgaatt ctcctcaaat aaaaaactat ttttcaatta gtagtctacc ataaattcca
    12901 ttatactgcg agatttgcag aaatgataaa taaatgaata aagaataaaa tttcacaata
    12961 tctgagcaat ggaattgatt ttttcctata aatactgcta tgatggagaa atcaaagatg
    13021 taattagaca atacgtggag gtcatttcgt gaaagatcat attattccaa aggcgacagc
    13081 taaaagactg cctttgtatt atcgctattt aaggatttta aataatgctg gaaagaaaaa
    13141 agtgtcttca actgaattaa gtgaagccgt tcaagtagat agtgcaacga tccgtcgaga
    13201 tttttcttat tttggcgaat taggaaaacg tgggtatggt tatgatgtag aagatcttat
    13261 gcactttttt gcaaagacat taaacgacga tcaattgaca aatgttgcgc tgatcggtgt
    13321 agggaacttg ggaagtgctt tactaaaata caaattccat caaagtaata gcatacgtat
    13381 cagttgtgct tttgatgtga atgaggaaat cgttgggcgc atcgtagacg gtatccccgt
    13441 ttatccaatg gaagatatgt cagaacaaat caagatccaa caaatcgaag tagcaatttt
    13501 aacgataccc gctgaaagag cacaagaagt agtcaatcag ttaacggaag caggaatcaa
    13561 aggaatcttg aactttaccg ctgctcgatt gaatgctccg tcagatgtat tgatccaaaa
    13621 tgttgatttg acgaatgaat tgcaaacctt gatctatttc ttgcattctg acgcaaatgc
    13681 gcattccgaa aatacagcag aataaaaata aaaagcgatt gaacaaatga aggcaaaact
    13741 ttcacttgtt caatcgcttt tttctgtttg gacaacgatt attttgttcg gaagatttct
    13801 tcataagaaa gggaatcatc ttctgctgtc agttcatcta gtagataacg gattttttta
    13861 aagtcgatga accgtgcttg ccgaaagact tcttttcctt gatgaaaaat caggacaact
    13921 ggcgcagtca gcacttcaaa tttactagct acttctggtg tttcaaatgc atccaaatga
    13981 agtgccggaa tatcataatg tgtgagaagt tcctctagtc gtggacgaac agcgtgacaa
    14041 acactgcaat taggcatcga aagataaatg acggcaacgg atgactgttg cagtatgtct
    14101 tgaacttcag tcaagttagt ggtttgtttc atttttattc tcccttttat gatagaagtg
    14161 atatgtatga gaccttaatt taatgggaat aacagaaaaa gtcaattgaa gtgctttggt
    14221 aaaaaataag agttgtgtaa aaatttacag agcaacttgt tttttttgaa taaaagcgta
    14281 tatttgcaaa gcgaatgaac tagaaataaa aaggaggaaa ctcatgtttt cttttattcc
    14341 aaattcggtt ttgcagatga gtacgatttt cttatcgatc gttattgaag cattaccttt
    14401 cgtattatta ggctgtctta tctcaggcgc cttacaagta tttttgaccc cagaacgtgt
    14461 gaagagatgg cttcctgaaa atcgtatctt ctctattttt actggttcga tcttaggatt
    14521 tttctttcct tcatgtgaat gcggcatcgt accgatcgtt catcaatttg ttaaaaaagg
    14581 cgtaccagtt cacacagcgt ttgcttttat gctgactgct ccgatcatca atccaatcgt
    14641 gattttttcc acttttatcg catttggcaa ttcttggcag atggcaagct ggcgggtgat
    14701 aggcagcttt tttgttgccc ttgtgattgg tgtctggctt gcctattttc aaaaagacgc
    14761 tgtattgaaa gaaaaaatca cgtctaaagt agcagaaaat caccatcatc atgtccatga
    14821 agaagaacaa agtgagaaga atgaaccaaa aaatcagctg atccatcaaa ctgggcatgt
    14881 gttgacacat tcaatcgacg aattttttga tacaggtcgt tatttgatca ttggcggatt
    14941 aatcgcagct gcgatgcaga cttatttacc aactagaatt atgctaacgc tcggctcaac
    15001 aaagatttta gccattatca tcatgctgtt attggccttt acgatgtctc tttgctcaga
    15061 agcagatgcg tttataggat cttctttgtt aagtctgttc ggcacagcac ctgtagctgc
    15121 ctttttggtc tttggcccaa tggtcgatat caaaaatcta ctgatgatga aacgatattt
    15181 tacaggacgc tttattttat cgctgatcgg actgattgcc cttagcgtta ttggattcac
    15241 attatttatt taggagggaa aatatgctgc ggtttttgat tttatctggg tatttcgaat
    15301 tgatgatgta cttgcaagtt tctggcaaac tcgatcaata tatcaatgtc cattatcgct
    15361 acttagctat tctttcaatg attttatctg ctcttttggc tttagttcag ctgtatttgt
    15421 gggtcaaaaa cggaaaagca gaagaaaagg cacacgagca cgatcatgac catgggttgt
    15481 caaaacctta tcaacgtgga atcgcttatg tactgctagc tttgccagta atcgtgggga
    15541 cgttgtttcc aacagttagt ctcgacacta cgatcgtaga agccaaagga tttaatttcc
    15601 cagtaagtaa agaatcagta ggggatccgg agatgcagac acaatactta aagccggata
    15661 ccagtattta tttcaacaaa tcagactact tagaccaaat gaatgagttg aaagaaaagt
    15721 atggggataa gcaaactatc aagatcacag atgaaaacta tttagaagtt atggagctaa
    15781 tttataatta ccctagcgaa ttcattggca aaaaaatcag ctatgaagga tttgtttacc
    15841 aaacaccgaa cgatagcaat acagatatct tcttgttccg attcggcatt atccattgtg
    15901 tggcagattc aggagtcttt ggtttgttga cgcatatgcc ggaaggagta acggttaaaa
    15961 atgatgaatg gtataaaata gaaggaacca tccaatcaga ctattatcaa ccattcaagc
    16021 gtgaaatccc atctgtagtt gttacaaacg ctgagaaagt ctctgctccg aaaaatcagt
    16081 atgtgtatcg ttctttttaa aagaacaaaa taaataaaca tagctcagac agctgacacg
    16141 caaggacgtc ggttgtctgg ctttttttgc atgatgtatt catttgtttg atatttattt
    16201 tagaagcagc atcctgaaag tatttgatat cggtttcaaa ggtgttggaa aagattgtga
    16261 agagaattac aatttattcc taacatgtat gttgaaaagt tgtatgaaat gattttgata
    16321 gtaaaatatc gagtggaggt actttttatg gtaacgcgta tatttatttt ggatgatagt
    16381 ttggtttttg aaaaaatgct agtagaaatt ttggaagaat ccagaatttt attaagtcct
    16441 tggaaatttg agatcgttca gggattgaac gttatacaat ttgttgaatt cattaaaaat
    16501 aatgaaatct attcctcaga tatttttttc ctagacatcg atttgaacgc ctattatagc
    16561 ggtatcgaac taggcgaaat gcttagagaa aagaatgaaa agtgtaaaat tgtttatcta
    16621 acgtctcatc cgaataaagc aataactgtt attaatcgaa agattacgcc tagtggttat
    16681 ttgataaaag aattcactta tgaaaaaaat aaaaaaagca tccaaagtta cttattgaaa
    16741 gaaaaagaaa actatcctgt tcaacatgct acgaaaaaaa ggtggacaac tgtccgttat
    16801 ggtaatagcg atcactatat ccattacgat gaaatccttt atctaatgag catgccaggt
    16861 tataaaaata aaataggcct agtattgaaa gatgaagaga ttctcgtaaa cggcacaatt
    16921 aaaaaatata aaaaatcact cgaatatgag tatttatgta aagatttaaa agcttatatc
    16981 attaatactg aaaacattac atctattagc agagtaaacg aaatagtaac atttgcaaat
    17041 ggagaacaac tagagatggg aaagagaagt attgataaac taaagaattt tatgcaagaa
    17101 aagatagaaa atgaatcatt ttaaagaaaa caaagactca tatcttacct gttagaagag
    17161 tgttttcctg tagaagagaa caacccaagt agcagcctag tcgtttctat ccttttttgt
    17221 tatgcactct ttttgacatt tactccacca ataacgaagg gtacaataaa aagtaataac
    17281 aaacaaaagg agtacagaaa tgattgaatt catcaatgta agtaaaagtt acgggaaaaa
    17341 acaagcatta aaagacttgt ctctctcgat aagacaaggg gaaatttttg gatttttagg
    17401 acataatggt gccggaaaat caactacgat taaaagttta gttagtatta ttgaaccatc
    17461 atcgggaacg attttagtag atggaatgaa attgacggaa aatcgattga gtatcaaaca
    17521 aaaaatcggt tatgtgcctg attccccaga tattttttta caattgacgg ctggagaata
    17581 ttgggacttg atttcagctg cctatgaatt agacacacaa aaaaaagaaa agcgtttagc
    17641 agaattgaca gcgctttttg atatgtatag tcatcaaaat gaaacaatcg caagtttttc
    17701 acatggaatg cgtcaaaaaa cgattttgat cggcacgttg ctgccagatc cagatatttg
    17761 ggtattggat gaacctttgc aaggacttga tcctcaagca gcatttgatt tgaaagaaat
    17821 gatgaaggct catgccgcaa aaggaaaaac agtcattttt tctacacatg tattggatac
    17881 cgcacaacag ttatgcgata aactggctat tttgaagaaa ggtgaattga tttatcaggg
    17941 ggcagttagt gaattattga atggctcacc tgatgaaacg ctagaaaaga tttatttgaa
    18001 aatggctgga aggcaagcga caggagatgg accgtatgta taagcgacaa ttattagaat
    18061 taattcgagt taatctttta tatgttaatc cacagctcac gaataaagca agagagaaag
    18121 gaaaaaaggg aaagcgatta actatctatc ttttgtctca aaatcttttt tcagggctga
    18181 tttttttact gatttacgga tttgctatgt ttgctatgaa ctttgttaaa ttgccaggtt
    18241 tctttactta ttacgtggca ctttttggta tgttaggttt aactcaaagt atatcagtca
    18301 tttataatat cttttttgaa ggaaatgacc tgcaagtatt tttgcctctg ccttttggac
    18361 aagaacaggt tttttcagca aagattttgg tagttgcttt gaccatcatt ccttttgttt
    18421 ttccgcttct agtcatgttt attttaaccg gatggcgagc tgatctaggg attttgctta
    18481 ctatcattat ctcaatcctt ttgttttctc tatttttgat tattcttttt tgtctggcta
    18541 gtttgattgt ttttggtttg gctcgaacag cagtgtttaa aaaacataga aaaacagttt
    18601 ctagtatctt gcttggcagc tcgatgctga tcgcatttgc tggaatcatg tggatgaatc
    18661 atcaaacggg gactattgaa aatgagttaa cagatcggca tccgatttcg atattattgc
    18721 cattctatga tgctgccagt cagccacttt ctcaacaagg tttattgggt tggggaatac
    18781 tagctatcac ggctctggga tttttccttg ctgtaaaaca gctgatagta ccaaagctta
    18841 cagagcaact gactgattca aacagtgagt tcaaaataaa aagaacccat aaaaagaacc
    18901 aaaatgtgca tcagctttta tttagttaca atgctcaatt agtaaaagaa cctaatttga
    18961 ttatgcaagt tctttcttct tccttgttaa ctccaatcat ttttattctt gcttttgccc
    19021 taggaggcga aataaaatta actgatttag ataataagtt aatcggtgtt gttttcctgg
    19081 tagggatcgc attggctttc ttaacagtta atcagacttc ttttatcagc aatcttattt
    19141 ctttggatca agaaaatttt ctgtttatcc gttctttgcc aatctctatg aaccaatatt
    19201 taaaagaaaa gttcagattc ggatggatat tgcagagttt tttaactggt gggatcgcat
    19261 tattaagcgg actgtctttt cagctgcctt tgttttttat ccctagcttg ctatttggtt
    19321 ctttattcgg ctgctactta ttgtcactac gttatttcgc tagagattat cggttgctgc
    19381 tgctgaactg gaccaatatt aaccaattat ttaacagagg ttcaggaagt ttgggtttag
    19441 tcgcaactat gatgggttca ttgatcatca gtattattct tatcgtctta tacggaatgt
    19501 tggctttgtt ttatccattt tggttagtga atattcctgt gatcggttta gttctaatac
    19561 tttccgctct atggatcgtt tattatcaac gaacgttttg gaaaaaattt gaataaagaa
    19621 gaggggccgt gacaaaaatc atgtcgcagc ccctttttta cagatagagg gtgttcaaaa
    19681 gtcagtttct cagtattaag tcaattttat gtaaaaatgt gagaagctat ttttacaaaa
    19741 ctttttttaa tactcataat tacttcttat tgctcctgcg gttacttgtc gcaatgtttg
    19801 tgagatattt tgtcatcgct caaggctgaa cgtctctttc acaacctttt ctttgttaca
    19861 cttcgtttat ttaaaaagcc gtttttttcg tttcatcatg attgcgtcac gctttacttt
    19921 gaaattacgg atgttatggt taaagacttc tgataataca agacctaaag cgattgctcc
    19981 agcaatcata attgcttgga ccgcataatg agccgcttct cgataggatt cagtaacgag
    20041 atttcgaacc gcttgataag ctaaaccacc agggactaga ggaaccatcc cgggaatatt
    20101 gaaaatcgtt acgggcattt tcaaacgttt agagaaaaga tcgctgatga atgctactcc
    20161 taaagaacca agcaatgaac caaaagcagc agatccgcct atttgaacac agatccagta
    20221 gatcatccag ccaaaagcac cagaaagacc acaacaaatc aatgaacgcc taggtacatt
    20281 tgtaataacg gcaaatgccg cagtcgctaa aaaactaaaa gaaaactgaa taaatatcgt
    20341 ccccatactt gtgttccttt cctaataaaa aagctggaaa ataaaagcaa tcgcaaaacc
    20401 gatcatcgta gcagtcatca tcgcttctgt tccgcgagaa actcctgaga cataatgtcc
    20461 agctagcaaa tcacggatag cgttcgtaat ttgaactcca ggaactaaag gcatcacaca
    20521 tccgataatg attagatcct gattgcttcc taagccaaaa cgtacgctgt agatagcggc
    20581 tatgccaatc aataaagaag ataaaaattc cgataaaaat ttgattctaa aaaatttcaa
    20641 actatataga taagctgcgt atcccaatcc tccaatgact aaagtcacag gtaaatcggt
    20701 catctttccg ccaaataaca ccataattgt tccactgatc actgccgcgc taacgatttg
    20761 caaccagaca ggaaagaaag aacggtctcg gtcgattgct tgcagttcgc agtaaagttc
    20821 ttctaatgtt agctctgaag caacatattt acgtgaaaga ttatttactt ttactacttt
    20881 ttctaaatta atcgaacggt tggtaatttg ttccattcgg atggtcgagg tacgatcaag
    20941 accaataaag agaccggttt gagtgacata gctgaccaaa cggaaatttc cagaagctaa
    21001 agcaattcga ctcatcgtat cttctacccg atacatctcc gcattgcttt ccatcatgat
    21061 tttcccagcg agtaaacaag tgtccagcaa cagatctaat tcttttcccg tcatagcatc
    21121 ttctccaata attgattgat tagttttatt ttactacaaa acataccaga agcgtaaaga
    21181 ataaaaaaac ttgaggaagg aataaaagag gcgtatactg tttttgtatt gcgggtgtag
    21241 tttagtggta aaatcccagc ttcccaagct gatgtcgcgg gttcgattcc cgtcacccgc
    21301 ttaaaatagg ttgtgaaaaa gctgctctgc aacaagtaat aagaacagcc aagcaaaaac
    21361 aacttcttat gtttttaact tggatggact tattaccgca gatgcaagct tttgcgcacc
    21421 gtttaccaag cggttgtgaa atcagtgtat tgtcttgagt atgaagaaaa tttttgaata
    21481 ataataaata ccttacagat agagtggtga ctgattagag acgaggaatc cgtctctttt
    21541 ttgtattttt aagccatctt aaaacaggtt ttattttttg ctgtttctat ttctttctag
    21601 tatttattta taggggaaca tatgttaaga tttagggagc tgttagtaaa ggagtaaaga
    21661 aatgagcaaa aaaacaacca aggcgatcgt ggggatcgtc gctgctgtga ttgcaggggc
    21721 attcggtgtt tccaccacac aaaaagattc agatatcttt cagcagatta caactatttt
    21781 tgattccaca ccacaagctt ctcaagtagc ggatgtgcca gaatatgatg gaaaacatca
    21841 agaaatagaa atcaatggga atcagccgga atttacaaaa gaggatctta gcctttccaa
    21901 aggaacatgg gaaagctatt caaatattga taaattgaac agagtaggac aagccaatgc
    21961 tatgcttgga aaagatttgt tccctactga aaagagagag cctttgtata ttgacccgac
    22021 aggttggaaa caaaagaaat taagtgacgg gcaatggtta tataatcgca gccatttaat
    22081 tggtttccag ctgactggtc aaaataacaa cattaaaaac ttgatgacag ggacacgttc
    22141 gttgaatgct ccatacatgc ttgctcacga aaatgatatt gcggcatata tcaaagaaac
    22201 aaatcatcat gtacgctacc gtgtcactcc tcattttgag gggaatgaac tggtagccag
    22261 gggagtgcaa ttggaagcag aaagcattga agacaaaaaa attgaattca atgtctttat
    22321 ctacaatgtt caagatggct acacgatcaa ttatgagaca ggacaagcaa caaaaacaaa
    22381 aaattagtag cagctattcg aattttttat gaatattatg aaaaaattgt gtaaaaacat
    22441 acattcaaag aaatatagcg tatactttat gaaaagagta cttttgataa agctacagaa
    22501 aaaaggaaaa aaacatacaa atagtgtttc ttaatttatt cggaagtttg gaatatttgt
    22561 ttgtagtttt ccctttcttc gagtaaaata aggttgtaga aggtaagctg gaattacctt
    22621 gcgggaaaga ggtgtagaat catgggtttt acagatgaaa ccgtacgttt tggttttgac
    22681 gatagtcgca aaaaagaagt gagcgaaaca ttagcgattg tttatcgggc tttggaagaa
    22741 aaaggctaca atccaatcaa tcagattgtc ggctacttgc tttctggaga cccgtcctac
    22801 attcctcgtt atcgtgatgc tcgaaatttg attcgccgtc acgaacgcga tgagatcatg
    22861 gaagtaattg tcaaggacta cctctcaaat catggagtga atttatgaga gtaatgggct
    22921 tggatgtcgg ttctaagaca gtaggtgttg ctatcagtga cccctttggc tggacagctc
    22981 aaggagtaga gatcattcgg atcaatgaag cagaagaaga gtttggcttt gatcggttga
    23041 aggaattagt agcacaatat gaagtagacc ggtttgtagt tggattacct aaaaatatga
    23101 acaattccat cggaccaagg gcagaagctt ccatgtcata cggagaaaag atcaaagaac
    23161 tattctcctt gccagttgat tatcaagatg aacgattaac cactgttcag gcagaacgta
    23221 tgctagtaga gcaggcaaat acttcaagag ccaaacgaaa aaaagtcatc gataaattag
    23281 cagctgtgat gatcttacaa aattatttag acggctcagg taagcaatta ttttaataat
    23341 aaaagaaaag aggtaatctt atgacagaac ataaccattc ccacgaccat gaaggacacg
    23401 aacacatcac attggtggat gaccaaggaa atgaaacatt atatgaaatc ctactaacag
    23461 ttgacggaca agaagaattt ggacgtaact atgttctttt atatcctgct ggtgtttcag
    23521 aagatgaaga tgtagaatta caagcttatg catacatcga aaacgaagat ggaacagaag
    23581 gcgagttaga acaaatcgaa acagacgcag aatgggacat gattgaagaa gtattcaata
    23641 cattcatggc ggaagaagaa gaatagacta taaagctagg agaaaccttg atatgatagg
    23701 gtttctcctt tttttatttt ttactgtatg ccatattgta tgccatctag tcaatattta
    23761 agtgttgtac taatttttca acagtctttt ctttcgtttc ttttgccaag tgaccgtaac
    23821 aatcgatcgt ctgactaatt tttgtatgcc gtaatctagt ttgaacttct accatagtag
    23881 ctccagcgtc caagagcatt gaagcatgag tgtgtcttgc tacatgcaca ccgagaaatg
    23941 gaaccatagc tttttcacaa atagtaatca atcttgcata aatagcgtgg tgtgtgatta
    24001 gttctttata gataccacaa aaaatcatag tcggatcagt tacaccaagt gtcagcatat
    24061 atttccgctg attaatctgc cattttttta atatagaaat tgttctttca tctagtggaa
    24121 gaaccccagc actacaatca gttttaggat cactgatttt atagccattt ttggattggc
    24181 ttagtgtttt attgatggtg accgtatttt cttgaaaatc aatgtctgac caattcaatg
    24241 caagggcttc actgatccta accccgctat aaaagagaaa gcgtagtaac gttttatcaa
    24301 agtcgtttcg ataagtttca ggtttgctgt ttaggtaatc aaacaaggtg atcagttgtt
    24361 ctttactgta aactttgacc ttttctttat gcttagtggt ggttctttta ggcattaata
    24421 cgttgtctag tggattagtc tcaataatcc caagattgat agcgtagcta aaaatacgct
    24481 tagaagttga atgaagtacc ttgtattggt cagtagtttc agcccagcta tttacaattt
    24541 gttgggcttt ttttaccgtg acttcattca cacgaagatt tccatatttt ggaagaatcc
    24601 actttctaaa cttgatttca gttttcatga aggtggcttc tcggacagtg gttttatatg
    24661 tttctagcca caagtcataa acttctttaa acgtttcgtt gttcgctttt ttaataccgt
    24721 ttttatcgta gtccacttgc aagcgtgaca aggcaagctg ggcttctttt tttgttttgt
    24781 aacctcgtct acgaacctta tcaggtttgc cagtcatttt gttcattcca agataggctt
    24841 catagagcca aaatttacct tttttagttt catattgctt gaatgttgcc ataatagttt
    24901 tccctccata gtgtagcaag ccgtgggggc ggttggagga ggcagtttat tattattttg
    24961 aatagtgttt atttagctca gtaacaagag ctgtgaactc ttttagaaga tcattttcat
    25021 aaaattcttg atactctttt ttctcatctg tatttttttc tgaatcatta attaatgagt
    25081 catatcgtaa aagcgtattt agaagagctg cgagataagc aattggggta ctcccgtcag
    25141 gaaattcaat tcgagatcct gttttaagat attttattgc gtttgttaaa taaatcttct
    25201 gtgagacagt caggttatct tcttcgatgt tattgatagc attagaaaga ttagaatcaa
    25261 ttatagagtt atttttttca atagtttttt tcaattgctt ttcaagcaca tttcgcttaa
    25321 tttcgggcat catatgcata tctcttaatg tataagatcc gtttaataga taggtagtgg
    25381 atacatctaa tacctttgaa agttgtttaa gcctggtgtt attgggaaga ttatagccat
    25441 tttcccaatt actaacggca cctttactgg ccggtgggga taatttacct ccaagttgtt
    25501 ccattgagag tcccttttca attctagcca gtctaattct ttgtcctgtc tccactgctt
    25561 cggggtattt ttttctagcc acattttcac caccattcat atattttctc tactatatca
    25621 cgatttaaat atgtgtgaaa cataaaagtt caaaaaagta tgttaaaatt cttgcaaatg
    25681 aaaaggtatg atggtatatt gagtttataa gaggtataga aatgtattca agagcctctt
    25741 gcattttttt aaaatctttg tatagaaatg tatgctaacg aggggggata aatatggaat
    25801 taaaaattga caaactcacg cttgatgatc cagcttttaa aattattgac gatcgagttg
    25861 ttcaacaagt agagcaaact caaggaacgt tactttcatt attagaaaaa aagtaccagt
    25921 ttccaaaata tatgaacaag gcacaagctg ctaagtatat gaacgtttca tacaatacta
    25981 tgatgcagaa atatgttcct aacggtttaa agttgattat agttgatgga gtcgtaagaa
    26041 tttcacaaga tgaatgtgat cgctttatgg aagaatacca aaaataaacg caagccgtgg
    26101 gggcaaaggg attaatagga ggaaataata atggaatcga cacaaaataa agcaatcgaa
    26161 aaagtattat caacaattct tacagaagac acagcggcag aattagcaaa cttggaaggc
    26221 aaagcgctag aagaaacgtt tgaatgtttg tacgaacaaa tggactatca aaaattgcta
    26281 ccacaagaac caacggtaag cggagtattg cgtggcttga acgatttagt acaagcagag
    26341 tttaaagaac gactttctat tgaagagtat caagaaattt tgtatcagca agttgagttg
    26401 ttagcgagct tgctagggct tgaactggag gacgttgaat gaaaactgaa atttggaacg
    26461 gacacattat aagatttgtc gatattaatg atgaatggtg ggcagtggcg aaagatgttg
    26521 cggaagcgtt aggtcttaaa caggttacta gagccattca ctctttgcct aaagatgggg
    26581 ttactactag taaggtcatc gattcattgg gcagaacaca agatgtaaac atcatcaacg
    26641 aaaaaaaata tttaccgcat ggcattcaaa agccgtaaaa aagaagccga ggcatttcaa
    26701 gactggattt tcgacatcat caaagaacta cgccagtcca caggacttga aggctttcaa
    26761 gtattccgca tgctagacaa agaacaccaa aaagaagcaa tgactaaatt aagccacgct
    26821 attactgaac caaaaccagt agactacatt aaagcgaatg tgatagccaa taaagctgta
    26881 tcaactattt atggtcattc caaaatggta aaaaagaaag atatgactcc tgaaatgttg
    26941 gttgatcgtg aacctatttt agatgagaca gtagaattaa tgactgttaa agaaaaatat
    27001 gggttgcagt tttcagtgag tgagaaaatt tataatcgtt ctgctgaatt gcagacaact
    27061 taggagcatt aacatgatcg agaacaaaga aaaagcctta tccataacag tcttggcgga
    27121 caggataaag gcaacttaat tgggataaaa cccgatattc tttgttccga ttataccata
    27181 ttaaaaaatc ggagggaacc attatgaaac gaaacttaat tataggaagc attttaatcg
    27241 gcggaatttt cggcttatta ccattaattg caaaaatagc tatctttgca ggattagcgt
    27301 tatatctctt cactgcttat gacgagtacg actatcaatt aagaactgga gggcataagt
    27361 agatgtacaa aacaaaacta ttaaaccaac tcgatagcct tgaattagag gaaattaatc
    27421 aagggatcgc tgaactagaa aataatatcg ggaaaaccta ctttggaaat tcattcaatg
    27481 aaaaactaac agttttgtat gtactcaaaa aacatgcaga acacaaaata atttgtcgag
    27541 aaatcaacga gctaaaaaat cagattttaa ccgcatggtt aaacattact gatatgcaag
    27601 aagcaagggt gaaaacattt aatacatggg taaagtatca gaatcaatta aaaggtgctg
    27661 aatttgttcg ggatgggttg aaatacgaac ttgagcagtt gaagctcatg gaggtgtctg
    27721 aatgatttat accagtattt tgaaaaagga ggagaggttt attggcaaat aattatcaag
    27781 cagcaacgga attacaaaag tcgggatggt caatttatcc cttatctcct ggaactaaaa
    27841 ttccaataaa aggctctagt ggttggaatg atgcaactaa cgattctaat caaattaatg
    27901 aatggtggac ggaagatgca actagaaata ttgggttaat gcttgaagat catcaaatgg
    27961 tggtagttga cctagatcaa cattctgaaa cacgaaacgg cgttgagaat tataaaaaac
    28021 ttgcttcaat gtatgatcca tttccttcta cttatacgga aatcacacca ggtaaaggaa
    28081 tccatttctt ctttaaaatt cctgatggtg taattatcca acaagaaaca ggtgcatttg
    28141 ctgatatctt cgggcgtgat gataaaggta aaagtttaag cgggattgat attatcacta
    28201 aaggagttcc aatagcgcca actatgatta tttcaagaag tgttgggaga gcatatgaac
    28261 ctattgaaaa cgtatctcta aataatattg caccagctcc cgattggcta gtgaacctac
    28321 tgctaaaaaa accgcaagaa ataaagactc aataccgacc cgtagcaaaa acagggacag
    28381 caaaaaaatt agatatgatt gttcaaggcg ctggcgaagg tagtagaaac gatcatttaa
    28441 ctaagttatg cggttggtta ctatggcacg gtgtagataa tcaaacttta gcagaattga
    28501 tttatacagc aaatgcgtac aatgaaccac cgctaaaaga taaagaagtg aatcaaatta
    28561 ttcgatcgat gattaaaaaa gatttgaggg ggaaagctca tggctcataa gcataaatta
    28621 gatagtattt tagactttcc cgaagccagc gagcgtgaag acaatatcat tgaattgaaa
    28681 acctggatgt cacgattaag atgcaataaa gacgatcaga ttaaaagtaa cagtgttgtg
    28741 aatgcagaat tgattttaac caatgatagc aatttagctg gaacaattgc ttataacgaa
    28801 tttagcggat acattcacct attaaaagat tctccttgga tcaatcgtac cgctggagaa
    28861 tgggaagaca gttttgagga tgccttaacg gcatatattg aagaaaacta caatgtagtt
    28921 tttgatgaca acaaaataca caaagcagta gtaaatgtgg ctagaaagaa tgttttcaac
    28981 ccagtaaaag aacgtatcga aaaagttaaa tgggatcaac agcctagact ggaaacactg
    29041 tttattgacc ttttaggggt agacgacaac ctttacacac gagaagtaac aaaacgttgg
    29101 atagtcggat cagtcgcacg tatctataaa ccaggaataa agtttgagat cgttccagtt
    29161 ttggatggac cgcaagggat tggtaagagt accgttccag cattacttta cacggatgat
    29221 tttttcaccg attcattaga ttcgctaggt gaaaagaaag atgattatat gcagcttcaa
    29281 ggcaatgtaa ttattgaact tggagaatta tcttcaatga acaaaactaa aattgaacag
    29341 ataaaaaact tcatcagtgc caagatcgat aaaattagac ctccttatgg tcggaatgtc
    29401 atagcttggg caaggcaatg tgtatttatt ggaacgtcga atgatgggca gtatttgaaa
    29461 gatgatacag gaaaccgccg tttttatcct ttgccttgta agaataagcc aaagatgaat
    29521 ccgtttaaaa caaaggatga atattttctt caagtgttag ctgaagcaaa ggtgcttttt
    29581 gataaaggac aacgaatcta ttttagtccc gatgaagata aagaagtctt agaaattgca
    29641 aaagactatc aagaggatgc caagatggag aatccaatta aagaagcaat cactaaatat
    29701 ttggaaatgg aaatcccgta taaatgggaa gaagctccag cgtgggcgag acgttcttat
    29761 tatcagaact atcctgacag taaatgtaat gagaaaaatt tacagcattt ctataatgga
    29821 gctactatgc aacaagagtt ttatttagtt gatagcgtac tcaccgctga tattttggaa
    29881 gctgtttttg ataaacaagc aaaggattta ttgaatggtc gatcagatgc agaaactaaa
    29941 aagattgcct tgattattag cagtattcct ggttgggaac ggaagcaact gccaaaaaga
    30001 aataaacgac gaggatttta caataagtca aatgcctatg aaaataaaaa tcgagctgga
    30061 aagtacaaaa agtaacgggt agtaacgggt cagtaacacc tagcccgtta ctagtttacc
    30121 cttactgccc caagggatac agcaatttgg taacggggta acaccttatt tccttaaaac
    30181 ttttgaaata gttagctaat atgctgggga ataatgttac tggattttac ccgttacctg
    30241 ttaccaaaac gctagaaccc ttgtccccgt tgggattgag tggtaacggg tacctgttac
    30301 gtaggtgtta ccacgtgtta cgaatcaagg aggaaagtaa atgctcaata ttatttcaac
    30361 aaacaaagca ccgaactttc aatatacaga tgaaatggat cggtttctaa tgaacacgct
    30421 ggcatttagt gtgggattgg taacagaaga ttattccaca tttgatccag aagtattaaa
    30481 gataatggaa gaagaacctg attggctgca ggagtcagta gcgtggtgtc aatcgctagt
    30541 agtgggatca ttggtagata gtggcaacta tgatgataca ggtgagctaa tggatgaatt
    30601 taattgtctg cttaacctat atgatcgagc gagacaacga gagcttacat cgaatgagga
    30661 taatttgttt ttaaacatcc atgataagtt cttggctttg ctactaacag atgatgaatt
    30721 gataactaat ttattggagg tagaataatt atgcatatgg aaagtattag atacttcgat
    30781 ggtgagaaac acattgagta ttcaaacact caagaagatg tagactttat tagttttgag
    30841 gaagataaaa tcactaaagt taattttaaa gacggaacgt gcttgaagat agtttcgcct
    30901 tatattgaat acaaatcaaa atgggaacaa gatgattctg acgaacgaga tcgctttggt
    30961 tggtaatcta tggcagttaa aaaacaatgt aatcatgctg gatgtaaaac attgattgat
    31021 tataggcaga agtattgtgg gaagcataaa gcaaagcaaa cggcaattaa gcgtgaagaa
    31081 agaaagcaaa gcgaaggtaa atattttcaa ttctatcaaa gtagaacatg gcgaaaggct
    31141 tcatacttgt atcggttaaa tcatccagta tgtgaggatt gcctagaaga aggcttgata
    31201 aggaaagctg atgttgtaga tcacaaaatt gaactaaaag atgattggaa tagacggtta
    31261 gatgaaacta attttcgttc tttatgccat gcacaccata attccaagac agccaatgaa
    31321 agacaaagac gagaaaagag taccctttga gttaaggggg catagtgtga aacttactga
    31381 caatcgatgc ctactcattt tggtacaaat aaccgttgtg aaaaggcata agggtaatta
    31441 caaataacga ttacacttgt aatcacaagt gaaaaagtat ataatgaaag taggagattt
    31501 attgaaaaat acaattgtta ttactgataa aacagggaaa cagcgcacca ttgagttacc
    31561 tcattttggt caagtgacca ttcaaatgca gaacggaaaa atcatttata tagataaatt
    31621 agataaagaa aaattctgat cgaaaaacga aggaatgtga gcttaattgc ttacgttcct
    31681 ttttcttttg tctgaaagga ggacaacatg ggacacccta aaatattaca cgatacaaaa
    31741 ggcaatatat caagtgaaga aaaagcaatc cgtgtggacg ctagagaaga attgttcaag
    31801 cagcaaccat taataaatat cacgccccct gactggatgg cagcgagcgc tagaagtgaa
    31861 tggaatcgta tcgtaccaac attaaaaaaa gattatccat tgagtgaagc agattatggt
    31921 tcattggtag cctattgttt agcctttgct cgaatgaaaa cagccgaagc cgagataaga
    31981 aaatcaggta cgtttatcac atgcgaaaac ggagtaaaga aagccaatcc agcggttcgg
    32041 gttcaatcac aagctatgag tgatttgaaa aaacaagcca cctcactagg tatgacctta
    32101 gaatcacgat caaaactagc tttgaacaag gttaaaaatg atgaacccga agacccgttc
    32161 aaagagttga tgaattcatg aatgattaca ttgagaaagt cctatcaggt aagctgattg
    32221 cacccaagaa aattatccaa gcgtgtgagc gtcatataag cgatttggag cgttctaagt
    32281 cagatagctt cccttatgtg ttcgatgaag aacaagccac caaagcgatt aaattcattg
    32341 agttgctacc atctacggac ggtaaagcaa tcaagatgtt aggatttcaa aaattcattc
    32401 taggcagtct ttatggctgg cgtactaaag aagggaatta caggcgattc aatcgagcgt
    32461 ttaccagtat gagccgtaag aatgggaaaa cgtatatcgc aagtggcatg gctgccaatg
    32521 cgttgattat ggaacaagaa ccagcagaag caaggcaagt attgtttgta agtaacgctt
    32581 tgaaacaagc taaattgggc tatgatatgc tgtctaattc acttagaaac gtggtcaagt
    32641 ctagtaagtt tttaagacca caactgaaaa ttatgaactc taagattcag cacttgccct
    32701 ctaattcgtt cgctatggca ctggctagtg aaaccagcac gctagatggg tttgcaccaa
    32761 caaccgcaat tcttgacgag tggcacgaag caaaaactcg taaaacgtac aacgtcatta
    32821 agtcaggaat gacccaacaa aagaacggct tattgtgtgt tattagtacc gctgggcttg
    32881 atttaaacgt tcctatgtac gaggaatact tattgttaga tcgtgtgcta aaaggcgaag
    32941 aacaagccga caggtacttt atagcgatat gggaattgga cgatcccgaa gaaattcacg
    33001 atcaagagaa atggatcaaa gccaatccga tttttgaaag tgaagaaatc aaaaaagtaa
    33061 tgattccaac cattcaagat gatgtgaacc ttgctttgaa acaaaataac cttaattctg
    33121 tattggtgaa aaacttcaat ttatggagac aagcgagtga ggacagctat atgattgctg
    33181 aagactggca ggcaaccgaa gtagaaccac aagatattac aggcaagccc gtttatatcg
    33241 gagtggattt atctaaaaca gatgatttaa ctagcgtttc atggatcgta ccgctagata
    33301 acggcgaact ttattgtgat tcacatagct ttgtagccac caaatatggg cttcaagaca
    33361 aagaaaagcg cgacggtttg ccttatcgag aactagaaaa agctggtgag tgttccatta
    33421 ctcaattaga aagtggaatc gtggactatg accaagtatt tcagtttatt caagatttga
    33481 ttcaagaaaa tgatttggaa tgtatgggga tttgttatga cccgtataac gctaattcgc
    33541 ttatcagtaa agctgaaaaa gccaactacc caatgttaga agtaagacaa ggaacgatta
    33601 ctctaaacgt tccgacccga acttttagag aacaagttta tgaaggcaac gttattcaca
    33661 ataaaaatac gattctcacc catgcagtga acaacgctat tttaaaaacg gataacaacg
    33721 gcattcagat taataaatca aagaacagta acaaaattga tccaatagct gcattaatca
    33781 atgcctatgt gtttgcaatg gattacttca ccacaacgga aggagcgaaa gcagacaatg
    33841 aattttatac aagtgaagaa ttttctttct aattacattc ataccgttct tttacttctt
    33901 ggattggtgt gtgtgttggt tgctatcacc ttactaacaa atgtctacta tggcttgtta
    33961 gcgctgggca tagtgcttat tggggtagcg gtcatgctaa atacagaaca gaagggaggt
    34021 taaaagatgg cattttttaa agcgagacaa aatacaacgg gagatccttt cctacaacat
    34081 gtggtatcaa tccaatcgga tgattacacc accagcttta caagcgttcg tgcattaaga
    34141 aatagtgatg tgtttgcagc cgttcgaatt attgctagtg atattgcttc aagtccgatt
    34201 caattggtca aaaacaatat gccacaagct gataatgaac tggtgaagtt actaaacgag
    34261 aaacctaatt cagaaatgga tggttggcat ttaaagtttg ctttggcggt caatatgttg
    34321 ctaaacggta atagctttgc agagattaaa cgcaacggtg aaaaggtaga agaaattcac
    34381 ttattaccta actcaagtgt aacggttact caattagata atggtacgtt gtcttatcag
    34441 attggtgata aaaaaagacg tgtgaagtct agcgatattt tgcacttcaa atatttcacc
    34501 caagatggtt taacaggatt accaccactt tatgcgttac gtgatgaact gaaaattcaa
    34561 caagctggca accgcacatt gcacaatttc tttactcgtg gtgtcagtgg gtcaggtatt
    34621 ttgaaggttc ataagtcaga tttagacgga tcagcaaaga acgcaattcg tgaaaagttt
    34681 gaagaagcca acggttcaag tagtggagat aatgctctta gaacgatcat tcttgatgaa
    34741 acaatggact acaaaacatt agaaataaac accgatgttt tgaagcttat caattccaat
    34801 gattggaaca caaaacaaat tgccaaggcg tttggtgtac cgattgagcg tttaggcgtt
    34861 gaaaatgaac attctagcac cgttcaaagt aatctccagt atatccaaag tacgctgatt
    34921 cattacttta atgtgtttgt gagtgaatta gatacgaaac ttgaaaccaa tatccgcttt
    34981 aattccgatc agttactaga gactgatcct gaaacaaaag taaaaaatgt attggatcag
    35041 gtcaaagggt cacttctcac gattaatgag gggcggtcga aaatggggct accccccatg
    35101 gatggtggcg atcgtttact agcaagtttg aactttacgt atttagatac gttggagaaa
    35161 tatcaattaa aagaacagga aggagttaca ccagttgaat aatgaagaag aaaaggaaaa
    35221 acggctgaca gaagaagctg agctaacagc cgattctccc aaagtagaga aagaaaatga
    35281 aaaacaacca acagacggca aaactatttc aggctatgcg ttgaaattcg ggcaaccgtc
    35341 aaaagattta ggcggctttg tagaagtgat tacacccgaa gcattaaaag aggtggattt
    35401 atcaaatgtg ttcttattat atggacacga ttattcaaag ccactagcta gtgtcaaagc
    35461 aggtacgttg aaattgaatg tcgatgatac aggattacat tttgaagcag agctaaccga
    35521 cacgacctat tcaaatgatg tgtatgagaa tatctcaaaa ggggttgttg attctatgtc
    35581 ctttgggttc gtgcttggat tagattcatt cgacaaaaaa gaagatggca caattgaacg
    35641 atcaatagat aaaatcaaag cacttaatga aattagtgtc gtgaccgttc ccgcttatga
    35701 ttcatcaaat gtccaagtaa ataagcgttc ttacgaatcg tttatgagta acaaccaagc
    35761 aaaacaaaca aacaatagct tagaatccac ttctaaagca caaaaggaga gtaataacat
    35821 ggaaaaaact ttaatcgata acgaaaaaac agaattgcgt gggtatgaag aatatatccg
    35881 ttcacaaggc gaagtgcgtg atggagtcac tactgtaaat gcagcggcag ttgttcccga
    35941 agaagtaatc ggtgaagtct ttgatttgaa acgttcaaat tataacttag ctcaatatgc
    36001 aacagtaaaa acagtatcaa atggacaagg taaatatcca gtagcaacta accaacaagc
    36061 agtgttagca acaaaagctg aacttgctga aattggtgat attgacgctg aaatgtttac
    36121 ttcagttgat tataaagtag aaactcgtgc tggtaagatt gccttatcaa atgaggttgt
    36181 ggaagattca gcagtgaata ttgtacaaga ggtcaaagat cagttagcga aattggtaga
    36241 aaacactgac aataagcata tcatggattt attaaaaaca ttcactaaga aaacggctgc
    36301 tacgttggac gatttgaaac aactatacaa tgtggcatta gacccagcat taaataaaat
    36361 ggtaattcta aaccaaagcg gatattacca cctagataca ttgaaagatt cagatggacg
    36421 ttacatttta caacccgatg tgacagcacc tagtggtaaa tcattattcg gtatgccagt
    36481 agtattgatt gcagatacat tgtttgccaa tcctaaagct ggaacattcc ctatgattat
    36541 gggggatatt gcacaatcta tctttgttgc tcgtagaaat caagtaacga ctcaatggga
    36601 aaaattcgat tactactcac aaggacttgc agtgatcgtt cgcaacgatt ataagaaaat
    36661 tgatcaaaat gcttcagtgt atattgagtt tacgccagtt gtaacaccaa aagtatagaa
    36721 aaatattggg cggcggttta tcccactgcc tttttttcat taggagagat aaaatggtaa
    36781 ttttggatag cataaaaaaa agtatgcgga tcgatcacac tattgatgat gactttattc
    36841 aacaattgat tgatacagca ggcgaatata taaaaagtgc tattgatagt agcgcaacgg
    36901 ataaagatat ggataattat cagcaatttg atttggcggt gtcattactt actcaacatt
    36961 ggtatttgaa ccgtcaagaa gccagcagcg aacggatacc agtaacggta caagcattag
    37021 tacaacaaat gagaggtgct tattatgcca atcattaaga atgtaaatga attgactgag
    37081 agagtcaagt ttaaaaagac aaaacgggta aaagatgaag atgggcagat ggtggatagt
    37141 gaagaaactg tatttgaatg ttgggctaat gtgcgttcac aaatgctaaa agacgtgctt
    37201 gctagtgtag gtaccattct tgaaggaacg ttgacgttta ttattcgata cgatcaagat
    37261 tatgaactaa caaacgatat gaaagtagct tggaaaaaca agagttataa aattatttca
    37321 atcaatgaag gaacggcgtt taaagattat acaacgatca tagctaaaca gatttcttag
    37381 aatgattaca cttgtaaacg ttgtgggtat ttagtataat taaggtagta aatgaagggt
    37441 tagctgcctg aattttgcaa gacttagcta gtcgaaatct attgttggac tgaaaattgt
    37501 aggtgtggtt gcaaacatgc tggactaaga aagatgatag atgatgaacg ttcaatttta
    37561 atacaggcat gctaggactg attggatggt tttggcaagc tgattgtgta gaaatcaaag
    37621 aacacgtctg ttgtggacgt gttttttttg ttataattca aaagaggtga tttaatggac
    37681 aaagcagagt ttacaaattt ttattggaag tattatctac atttagaaaa tgagtttatt
    37741 aataccacag attttgtgat gctcgatgag aataatttca aaacattctc tattgaatat
    37801 caaaaactac tactagcgat tggttcggag tgtgagatta ttttcaaaga actttgcgga
    37861 tttgatagca gtagcaataa aagcataact gattttaaag ctgttattaa atctagcgaa
    37921 ttaatgtgtt tggataatgg tgttagggtt atgaattctt taacattgac ttcactaaaa
    37981 ccttttggag atgggtggcc tgaagataca ccagattggt ggaaaatata taacagagta
    38041 aaacatggtc gttcttcaaa ttataaggaa gcaaatttgg aaaatgtgtt gtatgcttta
    38101 gcaagtctat atttattaga ggaatatttg cataagaaag taatactaga aggtgaagta
    38161 gactttataa gtccagagtc aaatctattt acgttatctt gggaaagaaa acattcgtcg
    38221 atgcaaaaag tgacgtttga aaaagtggat tcaaattatg tagctccact cattgatttt
    38281 aaagaacaag aagaaattta aaaaccccca cggcttattg aagtttttgt atgccatatt
    38341 gtatgccatt tggtttaaat cgcttgaaaa atagtgatag ataactctaa ttcatttagt
    38401 cataaacgct gttttgataa cctttatagt tctttgatat gggtttctca ttcatggcgg
    38461 aagaagaaga atagaacaaa agaatgaatt aataagatat aaaaaaaggg attgtgacaa
    38521 acgtcttgtc acaatccctt tttccaaata aacgatgttc aatcagctgc ccctcggcat
    38581 tcgctcgaaa aacggcgaaa tatgaagaac tattttgcca tttgtttctc taataatcag
    38641 gtcaaaacgt tgacttcaca gtctcttcct taaacggtgt tctcctgcca actcctcggt
    38701 cacaagtcac aatattcaac aaacatgaga agctgttttt tgaaattgtt ccttgtgact
    38761 cggagctgaa cggcaggctc acgacctctt tcttaaacgg tgttcaaaag cttgcatctg
    38821 cggtaataag ttcaaccaaa cgaaaattat gaggagctat ttttgtttgg ctgttcttat
    38881 tacttgatgc aggacagctt tttcacaacc tcttttcgtt tagcactaaa tttccttaaa
    38941 aagtagaaaa gctttcgaag cctcgtttgt ttcttttact gtataataaa agaaaagagt
    39001 aacaatcgct aaaagatata aacaagagaa aggaaataca agatgattgg tctgatttat
    39061 tttgtggtga tcgttctggc gaacacagtt ggcgctattt ccgggatggg tggaggcgtg
    39121 ttgatcaaac cgattcttga tcttatcggc gcccattctg ttgcagggat ttctttttac
    39181 tcaacagttg cggtattcac gatgtccatt gtttcgactg tgcgacaagt atcaagcggg
    39241 aaatcactga attggcagat tgtcggttgg gtatctagtg gagctgttgt tggaggagta
    39301 gtcggcaaca ttgtattcga agttttttta cagttatttg aaaacgagaa gcatgtgcag
    39361 ctgatccaaa tttttttgac ggtattgacc ttggtttttg cgttcttcta caccaagcat
    39421 catcagccaa aatttcattt gacgtcatgg acttggtacc ttatatgtgg gggggttctg
    39481 ggctttttag ctagtttttt aggtattggt ggtggaccag tcaatgtttc tttgttgatg
    39541 ctgatgtttg cattgccaat aaaagaagca acactatatt ctctatctac gattttcttt
    39601 tctcaactgg caaaattggt aacgattgct ttaacaagta gctttatgcg ctttgattta
    39661 tctatgttgt tttatgttat ccccgctgct gttattggag gtttgtgggg agcaagattt
    39721 agcagggttt tgtctccaaa aaaagtgacc tttatttttc aagtaattgt cctcgtggtt
    39781 cttttgatca atctttacaa tgctttcgtc atcttacaaa cattaggaga atctagacta
    39841 acgcaagtca aaatcactga aacatattgt tctaaatgaa aaaaggagta tactgtgata
    39901 aaaaaattca tttaaaaaaa taaaaattgg ctggtgattt ggatgttgcg ggaaatgcgt
    39961 ttaggagatg cagaagcact acgagaaatc aatgcggaac aattaggata tgatgtacca
    40021 ttaaccgtta cggtgagaca aatgaagaaa ctgttgaagg agccagaaaa aaattttttc
    40081 ttggtctatg aagatcctac ttctaaaaaa gcagctggct atgtacaagc ggagtcctat
    40141 gaatcgattt tcagcgatcc gatgttcaat attatggcac ttgctgtgtc taaacatgct
    40201 gaaaaaagag gaatcggaaa ggccttgatg actggcgtag aagaagcgaa aagacgagga
    40261 atatcagcaa taagacttaa ttctgcagaa tacagagtag aagcacaccg attttatgaa
    40321 cgcatcggtt atcattccga taaaatgcaa aaaagatttt tgaaaatcct gtaaattttt
    40381 atcaaaaaat acctggtcat caagccgata cttgatgatc aggtattttt tttgactaag
    40441 aaagtaattg catcaagaaa cctgagatga tcaaaacgat ggcaccacca agccgattgc
    40501 ccatttgagc aaaagcaata agttccatcc gattagctgc agataagaca gctacatttc
    40561 ctgtaccacc catcgagttg ttgcataagc cagcagtaat agttgattcg attggatata
    40621 aaccaaacaa acgaccgaca aatcctgaaa ctactgaaat cgcgataaca cttgtcaaac
    40681 ataagacaac aaattgccat gtcaaagcag aagccaatac atttagattc aataacgcaa
    40741 taccgatacc ggcaagaaca gctgctgtca agtttttgac aatcaagttg ttgaacatga
    40801 tagctgcatc ttcgtaatat tctggtaata ggtttgcgat tttacagata acaacgataa
    40861 tgatcatgaa tgcgtaagca tggactttag gaacaaaata gttacagatt tgtcctaaga
    40921 tgaagaaagt caatgatacc atcaaaccga cacctaattg tggaatggaa ggttttacat
    40981 ttctaggttt tccatcgcca aggtcgcctt tttccattaa tttaccatta ccgttgaatt
    41041 ttggcattga ttgtcccgca cgagcaacta acgctgcacc aatgatagct aggacatttg
    41101 tcattgctgt cgcaggaatc aggcgggaaa tgatagaaga agcgtccgta cctaaaacat
    41161 ttgcataaat cgttgataaa ggtacagctc cggctccaac accaccagcc attgcgggca
    41221 atgagatata taaaacggaa tttgcaaaac catttccgat aagcatacct acgagtccta
    41281 cggcaaaaaa ggagacgacc attgaaataa gtgcaacggg aataaaacga acagaagctt
    41341 tcatcaatag attacggttc ataccaagga tgctaccagt aatcaaggca gcaatataaa
    41401 agtctaaaaa gcccatattg ctgacaaagt tttctgtgga ttttactaca tactcaggta
    41461 agatcccaaa tgtagcaatc gcggcagagg caaagatcgc aaaaacggag ccaccaccta
    41521 aataactttt gacgataggg atttttgttc cgataaaatg aaataaatta ccgaaaatga
    41581 ccaaaacagc gattgggcca atcatattcg tcggtaattt tcctaaagcc attgcaatga
    41641 tcaggacaag gaccatgatc aaataaaggg gcaaacttac gccggtaatt tttgttgacc
    41701 aaaacccttc ttttttcttt tcctcaactg cagttgcggt tgttgttttt tgtgccattt
    41761 ttacagatcc tttcttattc tgtatcgtat gaaaaaagcc aaagagaagc ggcaaaagag
    41821 cagtagttgg ctggctgctg ttttgccgca gtcgcttttt tctttttaga cgtcatacaa
    41881 agtttctgta tgttctttta ctataacaat cttaatcttc taaagattta tattcaggaa
    41941 cccatttagc agattcaaca gcttctttga tatccgtgat ttcttcacga ttcaattttt
    42001 gtgcaacaac tgattttgcg acagtttcag caatcgtttg agagaattca gtgatttttg
    42061 ctactggagg caagatagct gctcctggtt ttgttacatc aacgattccg cctaatgctc
    42121 gactagcttg agaaatgatt tcagcattta ctcgtgtagc tgttgaagca atcaaaccaa
    42181 gccctaaacc tgggtacatc aacgcattat ttgcttgacc gatttggtaa gttacaccgt
    42241 tatattccac atcagcagca gggatacctg ttccaactaa agcttttccg tccgtccatt
    42301 caatcaaatc ttttgctttt gcttctgcca attttgttgg attagacaaa ggcatgatga
    42361 ttggacgtgg ggtatgagcc gccatttctt tcacgatttc ttcagtgaat gctccaggtt
    42421 gggtagaagt accgatcatg atcgttggat ggattgcttt tacaactgct tctaagtttg
    42481 tcaattcatc agcattagtg aattctgagc gtttacgagc gaatgggatt tgaccaggag
    42541 tcaatccttt tgtatcttca aacaataaac cctgtttatc tacttgatag aaatgttggc
    42601 gtgcttcttc ttcaggtaca ccttgacgga tcatttcatc taaaaggatg tttgcgatac
    42661 ctacaccagc agtaccagca ccaaatgtca agatcgtttg atctttcaat tgctcacctg
    42721 atatattcaa tccacctaat acaccagcta gtacaacgat tcctgtgcct tggatatcat
    42781 cattgaaagt agtgatttta tcttcgtatt tttctaagat cgttgcagca tttcctcgtc
    42841 caaaatcttc ccaatgtaat aacaattctg ggaataattc agtagctgat tgaacgaatt
    42901 gatcaatgaa ttcgtagtaa gtttcgcctt ctacacgagc atgacgattc cctaagtata
    42961 atggattatt caataattct tcgttattag taccagcgtc gattgataca ggcaagactt
    43021 gtgcaggatt gataccagcc gcagcagtgt agaccatcaa tttaccgata gcgatgtcaa
    43081 caccgttcac accccagtca cccataccta agattccttc tgcatctgtc acaacgatca
    43141 aacgaatgtc gcgtccatct gctgcgtttt tcaaacttgc tttgatattt tctggttcgt
    43201 cgattgaaag aaatgcagca tcttgtggtt tcaagaaaat ttcgttgtat tgttcgattg
    43261 aatccgcaac gacaggatca taaacgacag gcatgaattc aactaaatgt tcgcccatca
    43321 atttataaaa caatgtccgg ttcgtattga atagattcat taagaagata cgtttttcca
    43381 aatcggtctg tttgcttaag tattgaccgt aagcttggac agattgttgt tccaatgttt
    43441 ggacagtact tggaagcata ccagtgattc cgtattttgc ccgttcttct tttgtaaaag
    43501 ctgttccttt atttagaaaa ggattattta ataagtttag ccctgtaagc atgaatgatt
    43561 cctcctaagt tttaatacaa acgaagtata ggagtcagat gaggatatag tcaaaaagag
    43621 caggtataat aaattttatt tatatgagta atagagtcaa aagaaatcaa aatagcggta
    43681 tttgttcttt ttatatcaac aatccttgct tgattactat gcgtatctct tatatgctaa
    43741 agaaagaaaa gtagaagaat aaaggatatg ttagatagat aaatagaatc tctgaagaat
    43801 aaatcacgtg atcgtgacga taaaatacac ttacgtcagg tgataaaaaa tacataagta
    43861 gaaaactaag aggaggaaca gaaaatgaaa gaagttcaat tgatcagaaa aagcgaacta
    43921 tcagaaggtg gttgcaatgc atgcggcgta gtagaagcaa caagctatac attaaagctt
    43981 ggtgccaaca aagcgataat ctctgagttg acagtaggcg gtcttgtgga cagtctggcg
    44041 cttgctgaag gttttattgg agaagatatt tatgagatgt tttcagaaat ccgtcagtta
    44101 aaaaaagggg aaaactgcat agaggttcat catgagagcc cgaatgtgag attcaaacgt
    44161 ggtgataatg agatgatctt caataatcat gtgtccgatc acaccgagct atatggaatc
    44221 gtgaatcaaa tactaactga gctttttgga ttgggacctt atgcgttcaa ggaagaaaac
    44281 ggtaatccaa aattaaacga agaatggcaa gaaacgattg aaatacaaag aaacaacccg
    44341 cacttatttc aataggcatc cacagtattt cgtaaaaggg actttgacac gacttttgtc
    44401 aaagtcccat cgttttttat ctatttgtgt tctaaacatt tctttcagag tagtaacaac
    44461 tggaatgact gaaatgtaaa cagattattt gcctgtatca atacggaaga gtaatataaa
    44521 gtgtgtaaac gctatcatat tattcattca attttttata gagggaaggc attgaaatgg
    44581 aaaaaacgta tcaagcaggt acaaatgaag gaatagtgga ttttatcaat atggaagatt
    44641 tagaaatagc cgcttcacaa gtgattccag ctggtggtta tggttacatc agcagtggtg
    44701 ctggcgactt atttacttat caagaaaatg aacgggcatt caatcatcag ctgattattc
    44761 ctcatgtatt aaaagatgta gaattacccg atacaactac acattttgac aaagaaacgc
    44821 tgactgcacc aatcatcatg gcaccagttg ctgctcatgg cttagctcat gtgaaggcgg
    44881 agaaagcttc tgcaaaaggt gtagcagatt ttgggacgat ctatacagca agttcttacg
    44941 cttcttgtac attagaagag ataagagaag caggcgggga gaaagcaccg caatggtttc
    45001 aattttatat gagcaaagat gatgggatca atttggatat tcttgaagtg gccaagcgta
    45061 atggagcaaa agcaatcgta ttgacagcgg atgcaacagt tggcggaaac cgtgaaacag
    45121 accgcagaaa tgggtttacc ttcccactgc caatgccgat cgttcaggct tatcaatcag
    45181 gagtaggcca aacgatggat gctgtgtaca aatcttccaa acagaagctt agtccaaaag
    45241 atgtagaatt tattgctgct cattctgatt tgccagtcta tgtgaaaggt gtccagtcag
    45301 aagaagatgt ctatcgttca ttagaatctg gtgctggcgg aatctgggta tctaatcatg
    45361 gtggccgtca actagatggt ggtccagcag cgtttgattc gttgcaatat gtggcagaag
    45421 cagtagataa acgtgtacca atcgtgtttg acagcggtgt acgacgcgga cagcatgttt
    45481 tcaaagcaat cgcatcaggt gcagatcttg ttgctattgg cagacccgtt atttatggat
    45541 tgtctttagg aggaagtaca ggagtccatc aagtgtttga tttctttaaa acagaattgg
    45601 aaatggtcat gcaattagct ggaacacaaa cagtagaaga tatcaaaaaa ataaaattgc
    45661 gtgagaatcg ttttatttaa gaaacaaatg acgaaaaaaa taggagtgcg gcagatgatg
    45721 ccgtactcct atttttatag ttcaaggatg tcactaatag aataatttga aacgaaaaaa
    45781 taaaattgaa atattttttc atacttaata aaaaaggaag aatattcatg taaacgattt
    45841 tattgttttt ttctctttta tacaaaaagg gtcataattt caagtaagcg gatgaattca
    45901 tgaggatttt ttgcatactg tctctactat acttaggtca ctaagaaaaa ggagtgattt
    45961 attatgaaaa agaacatgat tgggacatta ttactttcaa cacttcttct aggcggcttg
    46021 gcaacaccag cttttgctga gggtcaagcg acttcaaaag gagatattac ctttactgaa
    46081 ccaacaaata ccgtggagcc tcttaaccct actgatcctt caaaaccagt agagccagca
    46141 gatccggaaa atccagcaac tggccagaca ggtcctttaa cactggatgt agttcccgaa
    46201 ttgccatttg gtacacacga gattgaaagc ggaacaaaaa cgtatcaagt agacgcttca
    46261 aaaaacgata caccttatct ccaagtatca gatcgtcgag gtgtaggtgc agatggccaa
    46321 gcacaagggt ggaacgtgac agtttcggtt tcagattttg taaacggttc acaagttttg
    46381 caaggcgctg aattagattt tggaacatcc actgttaaaa gtacgtcaga taacgaatcc
    46441 actggaccaa ctagtcaaac tgtaactggg ttgagtaaag caagtgcagc gacaccaata
    46501 tttacagcag caaaagatca aggtctggga acatggcttt ctgtttatga tccagcaaat
    46561 atcacactga aagtgccgaa agcagcagct ggaacattca cggctgattt gacttggaac
    46621 ctcgtggctg gcccagtagc atagagtatg aaataaattc aacaaactgc ggtgaaaata
    46681 ctataggtga aggatttttt accgcagttt ttgttgaaag gatgtggtgg acaatgaatc
    46741 aaagtaaacg actgtttgtt tcgttttttt ctattttaag tctatttttc atttttccgt
    46801 caatcagcca agcaaaggat tcagcaggag actttggaat caaaccggta tttccagaga
    46861 accaaataga taaagcaatc ggttattttg atttattagt ggcaccggaa caaaatcaga
    46921 cactagaagt aattatcagc aattcttcag atgaagaacg aacatttgag gtctctgtca
    46981 atccggcggt aacgagtgat ggtggaacga tcgattatag tcaaaaaaac ccaacgttag
    47041 atgagacatt gccgtttgat gtccgtgacg ttttgctcat tgcgaaaaag gaaatcaatg
    47101 tatcagcaca tgcagaaaca actgtaccta tagaagtgaa aatcccagca aaaagcttta
    47161 agggacgtgt attagcgggt attcatgttt cacctaaaga agaagctgaa acagaaaatg
    47221 ctacagaagg agcacaaatc aaaaatcgta ttgcttataa tctcgcagtc gttttacaag
    47281 aaagtcaaga gacgatagaa ccggatctga aacttttatc aggagatttg gacgaggtca
    47341 acgcaaagcc aactgttcag cttcgtttcc aaaatcctca gcctaggatt atcagcaatt
    47401 tgatatttac gagcaagatc ttttatgaaa atcagcttta tattgaaaat acgtctaatg
    47461 catttttagt tgcaccaaat tcgaattttc acttgaatct tgatttagct ggtgataaag
    47521 caaaagccgg cgattaccgc gcagaaatca tagcaaaatc aggcgacagt aatgaatggc
    47581 gatttacaca aaactttacg atcaaaaaag aaaaagcaca aaaagtaaat gaaaattccg
    47641 tttttgcagt acaagaacaa tctttcccat ggctttatgc aggattggtt gctgcagttc
    47701 tagtgttatg gttgattttg ctgtttttgt gggtccacaa gaaaaagaaa aaaggagaaa
    47761 caacatgatg aggtgatttc gttgaaaaca tcgatcttat tgggagggat tattgcaagt
    47821 ttgctgttct tcagctggca agagccagtc caagcagata ccaaaagttc aggtacgatt
    47881 acattttatg atctaagtcc aattccgcat ccaagtggtt cagtcaatgg cgcatcaaaa
    47941 cagcagacac agctaccgat ttataaagaa tctaatcaac atggcgtatt cccggagacg
    48001 aatgaacaaa agatccgttt tctttatttg atcattggta tagaattatg gcttcttgcg
    48061 tggttgttgt tatggagaag aaaggaaaag gaggatgaac atgttgctac aaaataaatt
    48121 ttcatttttt cgctccttct tttttacttc gctttttgtt ttaagtatat ttatcttttc
    48181 accttcggca gaagctgttg gagcaacgcc tcctgccatt tcttatgatc catacacgta
    48241 tgaaaatatc gtacctccaa atggtggacg tagtgcagtc aatggcggga agcttgtcca
    48301 actaactggg gctaaccaat tgcctaaatt gactgctact tatttgaacg atggttcaaa
    48361 tgatccttgg aaaggtggca cggtccgttt tcattgggaa agccatgtga aactaacaaa
    48421 tgtacttgat ttggtgaata tcactgcaca aggatttgca tttgtggcga tcatcaattt
    48481 gccggaacat gtatcaagca gtgatgtatt aaaagcaatt gactggaaca acgcctactt
    48541 gtatattgcc ggtgccccca tcaaggttac tagcggaagt ttattatcag caggaagcca
    48601 taccttgcgt tttgggatgg ggtcgtggga tacaaatact ctattgacag atattattgc
    48661 tattattacg cgaggcgaat tcaacgtgga cgatatcccg cttcaatttg atgttacagc
    48721 taatgtcgcg aagatgacag aaaacggaga taaatatgat acgagtccaa acaaaatttt
    48781 gaccaagggt aaattacaac cttctatgtc taaaaaggcc gttttttctg ttgattttta
    48841 tgattcgaat aatattatcc aagatcgtat gttcaattcg attttagctc cagctgcagg
    48901 tagattttat cctaaattaa ctggcggaaa cttgaatcca ggagcatatg cattttctgc
    48961 aagtgcagag ataaatacgt ggaatagtta catctcacca agtgattcaa caggaaaata
    49021 taatacattt gctgatacca cagaatacgt ggatggaaat aaccagaacc ttccaggctc
    49081 taccaatagt cggacattga cgatggggct gactgaagga cgttttgatc agttgccatt
    49141 tagtcgcttt gatcgcgtag tcaactattt tacaggaaaa aacgttacac aaggagcaat
    49201 actgactcat actccagcaa gcacaagtgg attgaatcag acagccaata tcgtgtacag
    49261 tgggaaagat gcgcaaggcg gattgctttc tcctgttgct ttaaaggtat tggagcagta
    49321 caagctagac ggaacggttt taccaacaaa cttaacagcc gatagtcagt ggggaaagct
    49381 cctttcttct gcatcgtacc aagtcacggc caattggtca gcaactgaac taaaaaaggg
    49441 ttcgatccat tacaggcttt attcgaaagg aacccaaaaa ttagcgacag gatggacaga
    49501 tcaacttttc caaacgatcc aatcaaataa cgggggtgta aatacagcta cttctacact
    49561 acctgcattg gcttcagggc aatattattt tgattatcgc ttggtggacg atgtacttac
    49621 taacatgtat ccgtcttttg cgtacaaatg gcagtctgaa caagctggaa tcaccactct
    49681 tcctcaaata acagtggcta attttccatc tgtgagtgca gatagtcagc taaaaaacct
    49741 tagcagacaa cctgagacag gagatcccct gtctgctcta tcaggagata cgattcaaga
    49801 aaatgtgaca ttcacgttaa caaaatctgg ggatgcgata accgacaaaa aaatcacgat
    49861 ctcacttcct gaaaatacta cttatatcaa tggttcctta aaattaaatg gtacaactat
    49921 cgcagatacc ggcattcaac aaggagtttc tgtcccagca gatctattga gcaaaatagg
    49981 agataccatt catcttactt acaactatca attaaatact gtagatactt ctttacaatc
    50041 cgtcagcata ctgacaaagg cagctgtact ttccagcaat attacattag cagatggtgc
    50101 taagcttcct aacccagttg tccaaacatc tgctaaaaca attcttgtcc ccaaacaaga
    50161 attaacatta gttaatgtac cagatgattt tacatttggt aacgatctcc ccaaaccgtt
    50221 gaagacaagt tattatgaat caaaaggcga tttttctttt gatgtgcggg atactcggct
    50281 tccaagcacg tctccttggc aactgacagg tacattgact tctttattta agaatgatca
    50341 aggtcaagaa ttaagcggaa caaaattata cttcaatcat tctggatcaa agcaattgat
    50401 tcagcaaggt caaaacacgt tgatttatga gagtgatgga acagctaaag gagaggttct
    50461 cgttgacttt cccgataccg atggtttact cttagaggta aatagcagta cgaatgctca
    50521 acctggcgca acgtatcaag gcatggtcac atggaaactg acagctgggc caaccagcta
    50581 agtgattaga atttgtatgg atctgtgata actgtcacag atcctctttt tcaaggatga
    50641 gaaggaaact tctgctgtta aaatcagaaa tgcttgaagg agtggacttg gaacttttca
    50701 gtttgcttga aaaaaatgaa caacggcaaa tcaaactttt ccaactttta ttagaggaaa
    50761 aaggagaggt ttccgttaat aacgtactta cccgcttatc agttgatcgg gctaccttga
    50821 aagaagatct gttttattta caagctaact tggaaaatat caaacaattg gaaattgtta
    50881 tccaagaagg gaatatttta ttaatcagac atggaaatat agcagcagtc gatgtttatt
    50941 atcattgtta cttgcgctat tctacaaaat atcagatact tctttatctg ttggaaaatg
    51001 gctcatttga tcggcagaaa cttgtcatgg aacttaatat cagttcggct actttgtctc
    51061 gcagagtgaa ggaattaaat gattctttaa atgagtttca tctgaaaata aaaagcgggc
    51121 ggctgaccgg tccagaaagt caaattcgtt atttttattt ccaattattt tggtttggac
    51181 gtccctatct tgaaaacaaa aaagaataca gtgatttatc aggaaacact tttttagatc
    51241 tgctgcaaaa agagtttagt tttgctatta cagaagaagg acgattgaaa tttgaaatat
    51301 ggctttccat tatgaagaag cgaatgcgct gtacgaaaaa atccaaacca gattatagca
    51361 atcttcctgt tggattgttt caaacgacac aatttttatt ggacctccat acatttttga
    51421 cccgttactt ctttcaatat gcctttcctt ggaatcaaaa tgaaacgttg gttttttatc
    51481 ttttcatgat cagtaacttt acattagata cacataactc gcatgtccag gagtttttga
    51541 taagcgaaaa atacaaagac gacgtagtag ctcaattgaa tcgaacgttt aaacaatcga
    51601 tagaagaata tttctctttt tatgtttttc cagaagagat ttcgcaaaag attgcgttga
    51661 cagtgatgca aaatcacgct cattttgcct attttagagg atggatgaat atttttggcc
    51721 aagaaggatt aaaacagcgg ttaactgaag tagaagataa acaattcctg gttttatgtg
    51781 aaagattggt cagacaaaca tttgctattg ttgattttac tgaagtagac gaggaaaatg
    51841 cccgctttga attatttgct cgctatgcat ctattttacg gacgctgatc aagcagttag
    51901 aattacgtct gcaaattgct tatgatcttc cttatgaaag gctaatggcg gatatcgtga
    51961 aagaaatcat ccaggaacaa ttgctgaata cgatcaaata tgatttagtc gaatacgaga
    52021 aagaaaagca gtatgatatc attttgacta gccaattgaa agagtacccg tcacagaagt
    52081 ccgctaaagt ttttgtattc actagcaacg aatataatta tgatttcccc tatttgaacc
    52141 aatttttaaa agaatgttat ttagaaaaat tgaatttaag gatgaataaa acatgaaaat
    52201 cgtgatcatt ggtgcttccc atgcaggcat cacagctgcc ctaaatctaa gaaaacttca
    52261 accgaaagca gaagttttac tgatcgatga agatcataaa gatggactag gctatgtttc
    52321 aaatggaatc aacctttatt taaaaggaaa gatacgtagt ttagctgaag ttgcccataa
    52381 catgcggact cttcaagaaa gtggggcaaa actgatcacc gaatggagag taactgaact
    52441 tgatccagac aaacatcagc tcatcctcgc atccaaagaa ggaaaaaacg agaccataac
    52501 ctatgataaa ttaatcgtag cgacaggttc ctctcctgtc accttgtata aacaaattga
    52561 agctgaaaat gtctacacct ataaaaatct agtgcaatct aagcaagtac ttgccgcttt
    52621 aaaagaagca aaagaagtag tgatcttcgg tgctggttac attggattgg aattagcaga
    52681 tgctttgaga aataaaggat acattattca tctagttgat tatatgccga atgttttatc
    52741 aagatatttc gataaggata tgatcaacag ttttcaaaat cagctgcaaa ctaagcaaat
    52801 aaatttttat ccaaatgaat tcttgatcga ttggaaaaaa tcagaagaga aagtagtatc
    52861 cgtacaactt ctgtctcaaa caataaaggc agatatggtc attttttctg cccaaactcg
    52921 tcctaatacg acattgttaa aagaaaaagt ggctttgtat gaggatgaga ctgtgatagt
    52981 caatgaatat ctgcagacaa gtgatccgga catctatgcg attggagata tcgtcccagt
    53041 cagttttgac aaaaataaac ggcatctctt tttaccttta gttactcgag ctgtacatat
    53101 ggcaagagca gtagcgctaa ctttgagtgg tcagccaacc gcttacgacc tcagacaaaa
    53161 gataacagca gcagtcatta tagactactt tttaggaact gtagggctga cagaagatga
    53221 agcgccattc ttggaacaaa ataccggttc gtgttcagga gaatttgatc tatttccaca
    53281 atacgacgaa gaaaacaaaa cagtaaatgc aaagctgatc taccatccgg atacattaga
    53341 aataattggc ggacagctga taagccaaga attcttatta tcagatttga acctgcttgc
    53401 ggatatcgtg aaacacaaaa ctacgattcc acagctagca gttgaggatt ttggatttct
    53461 gtctgaatac acctctcgtt ttcactacct caatgagtta gcttttaaag tactagctaa
    53521 gagagcaaat agcaatagag tagataaaag actgtgagaa atatcacggt cttttattgt
    53581 gtggggatat aataaatatt aatcaatcga gaataaaaaa ttcatataat gaaatagcgg
    53641 aagaattttt tgagcataat attcgccaaa aatttatcaa gtgataaaat tgttgtataa
    53701 aatgattatt tcaggaggag gagttaaatg tttttagcat taaatgaaat tatgcattca
    53761 aagttacgtt atgcgttagt tgcaggggtg atgtttttga tcgcctacct ggtatttttt
    53821 ttgactgggt tagcttatgg cttagctcaa gataatcgaa cagcagtcga caagtgggag
    53881 gcagattcga ttgtgctttc gaaagatgca aattcaaatc tagggatgtc catgattact
    53941 aagaagatag cagaagaagt cgaaggtggg aaagtggcgt atcttgccca aacacctgga
    54001 gtcgtgacta gtaaagacag tacagaagaa ggaaaaatca atgttagctt cttcggtatc
    54061 gataaaaatc aattcatcat gcccaatctt gttgaaggaa aagcttttga taacgatgat
    54121 gaggcagtag gcgatattag tttgaaagaa gaatatggtc tagccatagg agatacagtt
    54181 aagttatctg gtagtgacaa gacgtttaaa ctaactggct ttacggatca tgccaaattc
    54241 aatgtctcac cagttctcta tacaaccatc aatgcttacc aagaaatccg cttcgaaaaa
    54301 gaagatacaa gtgaaaatgc acggattaac gcaatagttg tcagaggtaa aatcagtaat
    54361 ttacctgaag atttagaaca gatcaaaatt tctaaattca tcaatgaatt acctggatat
    54421 aatgcgcaag tattgacttt tggatttatg atcggatttt tgatcgttat tgcggctatt
    54481 gtgatcggga ttttcattta tgtactgacg atgcaaaaga ttaatatctt tggtgtaatg
    54541 aaagcacaag ggatcacagg aggatttatt gcgcgttctg tagtggcaca aacattcatt
    54601 ttatcatttg ttggtattct tcttggtcta ttaggaacag tgggaacatc ccttgttcta
    54661 cctgatgcgg ttccattcca aagcaattgg ctgttttttg gcgtcattag cttgttgatg
    54721 ttagtagtag ctgtgttagg cgcactattt tctgttcgga caatcgtaaa aatcgatccg
    54781 ttgaaggcaa ttggataaga aggaggaaga acatgaaagc aatagaattt aaagaagtag
    54841 aaaaaagttt ccaagatggc gaccaagtag ttaaagcatt gaaagaaaca accatgagta
    54901 tcgataaagg ggaatttgtt gcaatcatcg gtccttctgg ttcaggtaaa agtacttttt
    54961 tgactttggc aggcggattg cagacgccta gcagtggctc tgtatttatc aatgatcaag
    55021 aattcagtaa tcaaaaagaa agcgaacgcg ttaaactacg ttttaaagaa attggcttta
    55081 ttttgcaagc ttccaatctg gttccttttc tgacagtaaa aaagcagtta ttattagtag
    55141 ataagattaa acatgaacat cgtcaaaaag aagcaaacga attatttgag cagcttggcg
    55201 tggataagtt gatcaacaag tatccagaag aactatctgg tggagaacgg caaagggtcg
    55261 caatcgctcg tgcattgtac aatgatccgt ccattattct agcagatgaa ccaactgcta
    55321 gtttggattc agaaaaggca cgagaagtag tcgatatctt ggcaaaagaa tcaaaagaca
    55381 aaaataaagc aacgatcatg gttactcacg atacacggct gattgacaaa tgcgatagaa
    55441 tatttatgat ggaagatggt gtattgaaag aaaaagaata accaaaaagc aggtggaaaa
    55501 atggtccatc gatacaacaa agatacacag caaaaaattt tgaaagaagc gactgacttg
    55561 tttatgtcca agggatatct cggcacttca acaagagaaa tcgcacaaaa agttgggatc
    55621 acccagccca atctctatca ttatttcggt gataaagaaa aactatatac ggcagtttta
    55681 gaaaaccact taaaagatgt tggaaaagct ttgagagaaa tcgttcaaac aagcgaaacg
    55741 ggatttcaag taaccttgac aaaaatggcg cagtttttga ttgagacaca tctggtcgat
    55801 ttgtttctga tgcttcacga tcttgaaagc aatctttcaa aggaaacaag agatcatctt
    55861 ttctttctat ggaagaaaaa ttatcgtgaa ccttttgaag aaatcttttc agcaaaccaa
    55921 tctgtgctaa gaaatgggat ttcaaaagaa atcgcagcaa ggcatttttt cttagtgtta
    55981 gcaccttaca tcactcggtc gaaaagacct gtggaagaac cgctaaatgt ggcgcaattg
    56041 atcgatttat atttgaatgg tgtattagga gaagcgtaaa gctgttatat agggagaaaa
    56101 tagttaggtg aagaagcaag atatgacgaa gatcgttata tcttgcttct ttatataggt
    56161 agtttttcat aaagacaaat ttgttattct ctcatgatta tcagggtata tttttattta
    56221 ttatgtcggt gttccaggaa gtgttttaat ttaataacga agaaattaat tgtttgtaga
    56281 atgaaggaaa ctatttattg ggtagatgaa tcaccacgaa tagtcaaaag gagatttcag
    56341 gatatgccaa aaatgaaaaa aatcatttta gcagtaatgt tattttctac ggttatatct
    56401 tttacagccc cttttttgct tacttaagct gattttaagt tttggccctt agtctggatc
    56461 tacgaggtga gagtcaagaa tgaaaaaaat aattggagct tttgtatttg caatcattat
    56521 cattattatc tgttttcaaa tagatgtttt tggtcaaaaa aagatagttg gacaaacggt
    56581 cagcagtacg aacagtacgg ttacaaagac aaaggaatca tttgatgata cagaacaaga
    56641 gacattaatc aaaatcggaa aaaatgaccg tacactatat acagatgact cgctaactac
    56701 cccacttgca actataaacg gcggagagct ggcggagttt ctttctgaaa caaaaaatgc
    56761 ttatcagatc aagacaaatg atggctatac tggatattta gccctcgaag atggaaccaa
    56821 agtcacaaag aatatacaaa caaaaccgga agagctatct gatgcagtga ttgtattaga
    56881 tcctgggcat ggcggaaatg atactggggc attaagcaat gatgaacaaa cagaagaaaa
    56941 agatataaca ttaagtacag ccataaaagt aaaaaaggcg ctagaggatg ctggagcaac
    57001 ggtttatttg acccatacta cagatgaatt agtacagctt ggagatatat gcgactacag
    57061 tgaagaaaaa aaggcagatg tctttatcag tttacacgca gactctacgg aatatgcgaa
    57121 tgaagcaact ggaatcacga catattatta ctatggacaa gaggaaacat tagcacagac
    57181 aattgctgac tccttcactg atctgcctct ggattcaaga ggaatctcca ctgggaacta
    57241 tcaagttctt cgagaaaatc ttcaaccttc tattttaatc gagatgggtt atatgaataa
    57301 tgatagtgat ttaaaggaat tagtaacaga cagttatcag cagcagattg ctgcaagttt
    57361 gacacaagca ttgaccactt attttcagta ataaataagc ccagccaaac aaaaatagct
    57421 cctcatattt ttcgtttggc cgggcttatt atcgcagatg caagcttttg aacaccgttt
    57481 atttttttag tagcttcaaa gctttttctg tatttgcaaa gtgaagtttg gcatattttt
    57541 caagcatagg catgccgcct ttctccaata gttttgccgc tacttggtca gatttcgttc
    57601 cagctcctga tggaagggtg attccagctt cagctgatgc tttgtgtaac tcttccaaaa
    57661 agctggcacg actgatgata gaagcagcag caacagctaa atgatattgt tctcctttag
    57721 taacgaagta cagtttttct tgtaattgat ttttttctaa acgcgcatat tttttaaaat
    57781 ttgcttccgg cgtaaactga tcgatcaaaa tcgcttctgg tttttctggc tcgatttttt
    57841 ttagcagcaa atggatcgct tgattgtgca aagcgacttt catccgaacg gcattgtatt
    57901 ttggttggat ctcattgtat ttttctggag ataagacaag cagtttatag gggatggttt
    57961 tttttaagat gtcagcaagc tggatgattt ggctatcttt taactctttt gaatctctaa
    58021 caccaagttt acgtaattct gcaagctgat cacgtttcac ataagcagca catactgtta
    58081 gcggaccgaa atagctgcca tttccgacct catcactacc taaaacggat aattgactga
    58141 tattttttgg caaagaagag gctgtttttg ctggcttggc ttgtttatcc tgtgcctccc
    58201 cccatttatc agcttctatt gctgcattcg taccttgaaa catcactttt ccggatgtat
    58261 aagcggtaat ggtcgtcccg tctttttttg cagcaaagct agtataagga atctgtttat
    58321 ttaacaaata agagcgatag tatgctttca tttgactaag ttggtcgttt gttgctttga
    58381 taatgacgtt gctcataaaa ttctcctcgt ttttatacat aaaactatac cgcaactcac
    58441 gacttttcgt tttctaagag attgcgagac atagcatttt tttaaagttt atcatataat
    58501 agttaagtat gtgaaaaata tttgtggaga acggtgaaag aaccaacttc atggtacact
    58561 aaataaaact ttcatcaaat aggaggaaat gattcgtatg gcgcacgaaa aaacacgcta
    58621 caaagcggtg attgccaacc aaacatatac tattatcgga cgggaaacca agcatcatat
    58681 ggatatcgta acgaagctga tcaatgaaca gttagcagaa ttgaaacaat tatcaccaca
    58741 aatggataat gaacaagcag caatcttgat ggctgtcaat gcgctttcgg atcaattgaa
    58801 gaaacaagaa agaatcttgg agctggaaga agaaacagca gaattaaaga aaaaaatgat
    58861 caaatttaca gagcttgaaa atcgtgtgaa acgcattgaa gcaatcgaga acgaagctcg
    58921 ggaagtattg aaagaaaatg gtcaagcaga tcataccatt aaaaatcatg tggaagcaca
    58981 acagatttta aacgagaaac gaaaaggaca aattaaacaa aaatcttcta attaagatcc
    59041 ttttatcaaa ataagaaaaa tttaaaaaaa gttagaagag aaaggaacgt agcatgctga
    59101 gtttgctgat tttattttta ttgctaattg cgtttttttc tggagcacgt cgcgggtttg
    59161 ctttgcaaat catattcgcg attggatatg tattgtcatt tattgctgcc cagcattttt
    59221 acaaaccatt agcaagtcat ttggaattat acattccata cccagctgtc acgccaacat
    59281 caaagttagc attttttgat caggtatttg cctttcacct agatgaagct ttttatgcag
    59341 gaactgcttt tctgattatt ttgctaattg gctggctgct tacccgattt gtgggggttt
    59401 ttgtccatgg attgacgtat gtgccgatct tgagacaggt agactggatt gcaggaggca
    59461 tcctgtcact aatcatggct tacgttacta tatttttgat tttgcagtta cttgcctttg
    59521 ttccattaga tgtggtccaa aatcaattcg gcgagcatag tttcgctcgc tttatcgttg
    59581 agagaacgcc atttcttacc aacaagatgt atgagctttg ggtaacgaat attttgaatt
    59641 aaggaaaata gtgctggaaa atatttcgtt ttttgtacag agtagattat ttaagaaggc
    59701 tgcgtagcgt atgtccggca cagctctttt ttcatagtga aagataaggt gataaaatga
    59761 ataaccgaat ccttgaaaca ttggaatttg aaaaagtcaa acagatggtc agacaatttg
    59821 tagtgactgc acaaggaaaa gaagaactgg cagaattggt accagtgagc gaggaacaaa
    59881 cgatcacaaa ctggcttcaa gaaactgagg atggattgaa agtgcaacgt ctgcgaggcg
    59941 ggatccctat acctaaactt gaaaatatcc gtccccatat gaaacggatt gagatcggag
    60001 cagacttgaa tggagtggag cttgcacaag tttccagagt attgtctacg acaagcgaat
    60061 tgaatcgttt cattgatgat ctttatgaca gtgaaatcga atttgcacgt ttgtatatgt
    60121 gggcagatca gttagtcacg atccctgttt tgagccgccg tttaaaggaa gcaatcgatg
    60181 aagacggacg cgtgactgat gacgcttctc ctgagttaaa gagcataaga cagaacattc
    60241 ggcgaagtga acaagctgtt cgtgaacagt tagatgggat cgtccgtggg aaaaatgcaa
    60301 agtatttaag tgatgcgatc atcaccatgc gaaatgaccg ctacgttatc ccagtcaaac
    60361 aagaataccg cggtgtattt ggcggtgtag tccacgatca aagtgcttca ggacagactt
    60421 tatttattga accaaaacaa gtggtggatt tgaataatcg tttgcgtcaa taccaaatcg
    60481 ctgaacgaaa tgagattcaa cgtattttaa gtgaactttc tgctgaactt gttccccatc
    60541 gtcaagaaat catccacaat gcttatgtga ttggtaaaat ggatctgatg aatgcaaaag
    60601 cacgatttgg taaagaagta aaagctatcg tgccgggaat cagtgaagac aatcatgtcg
    60661 tcttgaaaca agcaagacat ccactgatcg atcaggaaaa agtagtttct aatgacatca
    60721 caatcggaaa agactatcaa gccatcgtca ttacaggacc taacacaggt gggaaaacga
    60781 tcacgttgaa gactttaggt ctgttacaac tgatggggca agcaggatta ccgattcctg
    60841 caggtgaaga aagtcaaatc ggtatttttg aggaagtatt tgcggatata ggagacgaac
    60901 agtcgattga gcaaagtcta tcgacctttt cttctcatat gacgaacact gtagatattt
    60961 tatcaaaagt caatgaaaaa agtctggtat tatttgacga gctcggtgca ggaacagatc
    61021 cgcaagaagg tgctgctcta gcaatcgcaa tcttagatga tcttggtaaa aagtctgctt
    61081 atgtgatggc aacaacgcat tatcctgaat tgaaagttta tggatataat cgggcaaata
    61141 cgattaatgc cagcatggag tttgatgtgg atacattaag tccaacgtat cgtttgctga
    61201 ttggcgttcc tggacgaagc aatgcgtttg aaatctctag ccgattaggt cttgatacag
    61261 aagttattga tgaagcgaag cagttgatga atgatgagag ccaagattta aacgaaatga
    61321 tcacagattt agagaatcgc cggaaaatgg cagagaccga atatctggaa atgcgtcatt
    61381 ttgtttctga ggcacaagaa cttcacgatg atttgaaaga agcttacagc tatttctttg
    61441 aagaacgtga aaaagaaatg gaaaaagcaa agaaaaaagc aaatgaagtc gtgtcagagg
    61501 cggaagaaaa agcagaaaaa atcattgctg atattcgtaa aatgcaacag cagattgggc
    61561 aaggaaatgt gaaagagcat cagttgatcg atgcaaagac ccaattagca aatctacatc
    61621 aagaagaaac tttgaagaaa aataaagtat tgaagaaggc gaaagaacaa aaaacgttga
    61681 aaccgggaga cgaagtgttg gttacgactt acggccaaag agggacgctt ttacgtaaaa
    61741 acgggaatca gtggcaagta gaaatcggta tattaaaaat gaatgtgtcc gaagacgagc
    61801 tgacgcctgt tgctcctcaa aaagagccga cacaacgagt tatccatgct gtacgatctg
    61861 aatctagtag tcacgtgccg aatcaattgg accttcgagg aaaacgatac gaagaagcgc
    61921 taagtgaggt agatcaatat ttggattctg ccattctagc tggttatcct caagtgacta
    61981 ttgtccacgg aaaaggaaca ggcgcacttc gcaagggaat tactgattat cttaaaaacc
    62041 atcggagcgt caaaagcttt gagtttgcac cggcaaacca aggcggaaat ggtgcgacaa
    62101 ttgttaaatt taagtaaagc ttactaaagg taagcagatg gttcgctatc caagtataga
    62161 aatgctatac tagtcataga ttttaaaaat ggaggtcttt gatatgtcac aagtaattac
    62221 agataagaca tttaatgaag aaacagataa aggacttgta ttgattgatt tttgggcaac
    62281 ttggtgtggt ccatgtcgta tgcaagcacc gattttggat cagttggaac aagaatatga
    62341 tgaagaagaa ttcagaattg ctaaaatgga tgtggatgaa aatccagaaa ctcctcaaca
    62401 attcggtatc atgagcattc caacattaat gttgaaaaaa gatggtcaag tagtagaaaa
    62461 agctgttggt gttcattcaa aagaacaact acgtcaaatg atcgatcaat atttataaaa
    62521 acttacagca aaaataagct gagggtggga ctgaatccag ttccgtcctc ggtttttttg
    62581 cggttgagtt aaggttattc aaattaatat tttttgagta taattacgtt gtcaggctgg
    62641 attgtttttt tgacagacat gctataataa ctttaattga atatgaaggg gagtaccaga
    62701 tgaacgaacg aatcaaaaac aaattagctt tacttcctga tcagcccggc tgttacttga
    62761 tgaaagataa aaatggaacg atcatttatg tcggcaaagc caaaatatta aaaaatcgtg
    62821 tccgctcata ttttactggt agccataata cgaaaacgga acggcttgtt agtgaaatcg
    62881 aagactttga atacatcgtt acagaatcga atatcgaagc attgctctta gagatcaatc
    62941 tgataaagaa aaatgatcct aaatacaaca ttatgttaaa ggatgataaa acctatcctt
    63001 tccttaagat aacgaatgaa aaatatcccc gtttggtgat tactcgtaag gtactaaaag
    63061 acaaagcact gtattttgga ccatatcccg atgtcggtgc ggcgaatgag acaaagaaga
    63121 tcctcgatcg attatttcct ctgagaaaat gcaaacctag tcagacgaag gagccttgtc
    63181 tttactatca tttgggacaa tgtctgtgtc cttattattt cgacgtagat ccgaaagtct
    63241 atacgaaaat cgttgatgaa gtgaaaaact ttttaaacgg aggacacgaa aaaatcgagt
    63301 cagagatcca tcagaaaatg gaaaaagctg ctgaaaacat ggagtttgaa aaagctgcag
    63361 aataccgaga ccagatccgt gccattgaga caatcatgac tcgccaaaaa atgacaaata
    63421 ctgatttact ggatcgagat gtatttggtt atgcgattga taaaggatgg atgtgtgtcc
    63481 aagtgttttt cgtaagacaa ggaaagctaa ttgaacgaga tgtttcaatg tttcctttct
    63541 ataacgaagc agaagaagat ttcttgactt acctcggtca gttttatcag gaaaatgagc
    63601 atttcattcc taaagaagtc ttgattcctg atacgatcga caagcccagt gtagaagctt
    63661 tgttagctac gaaagtgctg caaccaaaac gaggagaaaa gaaaaaatta gttgaattgg
    63721 cgagtaagaa tgcctcagtt gctttgaatg aacggtttga tctgattgcc agaaaacagg
    63781 aacggacgat cggagcagtt gaacgtttag gaaacgcgat gaatatcccg accccaatac
    63841 gtatcgagtc ttttgataac tctaatatca tggggacgaa tcctgtggct gcgatggtcg
    63901 tattcattga tggaaaaccg gcaagaaaag aatatcggaa atataaaata aaaacagtca
    63961 acggaccgga tgattatgca tcaatgagag aagtcatcta tcgcagatat tcgcgagtga
    64021 ttcgcgaagg gttgccttta cctgatttga tcttgatcga tggaggaaaa ggacaagtag
    64081 atgtggcaaa agatgtctta gaaaatcaat taggaatcga tattcctatt gctggcatgg
    64141 caaaaaacga taaacataaa acaaatgagt tgctattcgg tacagatttg gctgtagtac
    64201 cgcttgagcg aaattcacca gagtttttct tactccagcg aatccaagat gaagtccatc
    64261 gattcgcaat cactttccat cggcagctac gcagtaaaaa cagttttgct tcccgattag
    64321 atgaaattga agggttagga ccaaaacgaa aaaaaatgct gcttaaagag ttcaaatcgt
    64381 tgaaaaatat cacagcagcc acgacagaag aattacaaga aatcggactg ccgaaaaatg
    64441 tcgcacaaaa cgtatttgat aaattacatc aggaatgagg aaagggcact ttacaaagaa
    64501 agtaaagtgt cctatcattt tatgtacaac aaaaagagcg tttacgtttt gttggtaaat
    64561 aataaatcgc ttacgtctgg tgtctaagga tatatgtgat ttcttgaaga aggagtgaag
    64621 aaatgttaga agtcaaggat cttgttaaaa cttttgggaa ctacacagct gtcgatcatg
    64681 tctctttcca aatccccgat ggaaaaatca tggggctaat tggccaaaac ggggctggga
    64741 agacaacgac ttttcgtttg atcttggatt ttttgacaca agaccaagga gaagtgttat
    64801 ggaatggcca tcatcttggg gagaaagatt atgatgtcat cggttatctt ccggaggaac
    64861 ggggacttta tccgaaagta acgattcaag accaactgct ttattttgca gaacttagag
    64921 ggaaatcaag aaaagagatt gaaccaaaaa tcgacttttg gatggaaaaa tttcaggtaa
    64981 aagggaaaaa gacggataaa gtaaaatctt tgtctaaagg aaatcagcaa aaagtccagc
    65041 tgatcgccac gttaatccat gaacctaaat tgatcatttt ggatgagcca ttcagcgggt
    65101 tagatccggt aaatgctgaa ttgctaaaag atggaatatt ggaattgaaa aaacatggtt
    65161 catgtgtcat tttttctagc cacaatatgg ataatgtaga aaaaatctgc gatcatttga
    65221 tcatgttgcg aaacggaaaa atggttttga atggaaaagt acatgagatt cgtgaatcat
    65281 ttggccgtac gaagttattc ttggaatctg gtttaagcca acaggaagta gaagaaatcg
    65341 aaggcgtgaa aaaagtgatc cttcatgaag acaatacgtt agagattacc ttagaagatc
    65401 ctgaagctgg gaaagaaatc tttactcgtg cgactcagtt cggctacatt cctatgttta
    65461 accagcaacc gccaactttg gaagagattt tcaaattgaa agcaggtgaa atcgatgcgt
    65521 aagttttgga ttattaccaa agatgtctat ttaaaaaatg ttaagtcgat ttctttcttg
    65581 atcatgatat tagtcccttt tatcatgctg ggtatcattt atgtagcagg aaactttgct
    65641 caacaaaata gtgatgtcaa taaaatcggc gtattggctg ataatgagca aatcagtcag
    65701 caaatgagcc aagtcaaaac agatgatttt gagttcaaag cagttgattc tgaagaaaaa
    65761 gcacaaaaag agctttcgga agaaaaaatc gatgcgtatt tagtagtctc aactgagaat
    65821 gataagataa atgggatgct ttatagcgaa aattcattag gacaaagtac acaactactg
    65881 atacaacaac aactgactgg cttgcaatcg atgcttcgag cgagtcaatt aggcatttca
    65941 ccagaagaag tagctagctt gagccaacaa gcaagtttga ctcgacaaaa agtcaatttt
    66001 gattcaaaag gaaaaatgac agtcggagaa gataactcga cagtccaata cgtcgtaagt
    66061 tatgtagcaa cgattgtctt gttcattatt attttgacgt atgcgcagat cattgcacaa
    66121 gagatcgctt ctgaaaaagg cacgcggatc atggaagtga tcctgtccag tacgactgca
    66181 caaaagcatt tttacggaaa attaacaggt gttttacttg ttgcattaac gcaaatggca
    66241 ttatacggta ttatttttgg tataggatac agtcaattca aagatatgga aatggtcaaa
    66301 aatatattag acggtatctc attggataac ttgattggac cattcttgtg gtattctctt
    66361 ctattcatga tctttggcat tttgattttt tctgttttag cagctttatg tggctctttg
    66421 gtcaacaaag cagaagatac agcaaaagca attttgccag tgacttatct atctctaggc
    66481 ggatacatgc ttggattgat actaggagct tcagatccaa acaatatcgt tattcggatc
    66541 acttcgtata ttccattctt atcttcatat attatgccgg ttcgcttagc aaatgagaca
    66601 gtcggtatgg gtggagcatt gatttccttg ttggtacttg tagccgtaac attcttattg
    66661 atgatcttgt ctgcaaacat gtacaaatcg aatgtactcg tttatagcga aggcggatta
    66721 tggagttcat tgaaacaatc gatttcaatt atgaggaatg aacgaaaaaa agcataaaac
    66781 aatcctaaaa tacagaagga agctggacat ctattgttcc cagcttcttt ttgtatagac
    66841 ctattttatt tattttacta tattggatat atattcattg aaaatagtgt ataacaactt
    66901 tataatattg agtataccaa tttttggagg cgttttaatg gaccgttatt tagatttact
    66961 ttcagaaaaa ttcccctcaa cggaggatgt catcacggaa atcatcaatc tcgaagcaat
    67021 tttgcagctt ccaaaaggaa cagagttatt tttgagtgat atacatggcg aatttcctgc
    67081 ttttgatcat attctgcgta tcggttcagg aaatcttaaa gaaaagatca aagacctttt
    67141 ttctgaacaa atgacggaaa cggatatcag ccaattcact atttttacgg cttatccaga
    67201 atatgcatta acgactgatt ggtacaaaga acaagataaa tcgcagctga tccatcattt
    67261 gatcgatctt ttacggttta cgacagtcaa atatacccgg tcaaaagttc gaaaaggatt
    67321 gccgaaagaa tatagctata tcattgagga actcttgtat atcgatgacc gtatcaatgg
    67381 aaaaaaagac tatgtaaaaa aaatcattga acaacttgtt ttgatgaagg aagaagaaaa
    67441 atttttaacg aaacttgcac agacgatcca aaaatctgtc atcgatcatt tgcatatcgt
    67501 tggagatatt tttgaccgag gaactcaagc agccaaagtg atggatcgaa tcatggattt
    67561 ttcttctgta gatatccaat ggggaaatca tgatattttg tggattggtg cgtattgcgg
    67621 ctctgaggca tgtttactga cacttttacg gattgcagca cgctataatt atttatttga
    67681 attagagaaa gaatatgggt tgaatttacg tccattgttt tcttttgctc atcaaactta
    67741 tcagaagaat ccagtatttg cgcctaaaaa cagtaaaaat ctatccgaaa gagagcaaga
    67801 agaattagaa aaaatccatc aggcactttc tatccttcaa ttcaaatcag aacatcagtt
    67861 attggatcgt cgacctgaat ttaaaatgga cgatcgtaaa ttgctggaaa aaatcgacta
    67921 tgaagcatca acgattgatt tagaaggtca gctctatgag ttgaaaggaa cttgttttca
    67981 aacgatccag ccagatgatc caaaaaaatt cttggaagag gaacaaaaag tgattgatag
    68041 tttgatgtat tcattccagc actctttgag aatgcaaaaa catatgacgt ttttgatcga
    68101 aaaaggggga atgtatctca cgaacaatca gcatgtgctg tttcatggct gtatacctgt
    68161 agacgagaag ggacagctct tagcatttga attagaccaa tcttatcgcg gaaaagaact
    68221 gctgggcttt tttgaaaaac agataactga aagcgcaaaa gatctgactg caaaagaaga
    68281 tttagcaacc gatttgattt ggtatgcgtg gagtgggcca ttttcgcctt tattcggcaa
    68341 gagtaaaatg gcgacttttg aacgttattt tctcacagag cctcatacgc acgtcgagaa
    68401 aagcaatcct tattatcact tgcgagatga agagtggttc agtgaaaaaa ttttagcaga
    68461 attcgacaca aaagaagaag ggtcagcaat cattaatggg cacacgccag taaaagtaaa
    68521 aaaaggggag tcaccgatca aagcaaatgg aaaagtattt gtcattgacg gaggtttatc
    68581 caaagcttat caaaaaacga caggaattgc cggttattca ctattatgca attcttatgg
    68641 tttccaaatc gtgacacatt atccgttttt gcctattgaa caacaatttg caaaaaaatc
    68701 cgaccaaaca aatgtgaaaa aagtaatcga acagcaacta ccacgcaaac tcaatcgtga
    68761 tacaacaaaa ggtatggaac tgcagcagca gattacccag ctcaaaaggc tgttggacta
    68821 tcgaaaggac gattgagaag aattccagtg aacattgttc catagactgg agactgagac
    68881 aaaagtcgtg tcgcagtctc tttttccgga taaacggtgt tcttctgcca actcctcggt
    68941 cacaagtcac actattcaac aaacatgaaa agctgttttt tgaaattgct ccttgtgact
    69001 cagagttgaa cggcaggctc acgacctctt ggtataaacg gtgttcaaaa gccagtttct
    69061 cggtattaag ccaaatttat gcaaaaatgt gaaaagccat tttcacaaaa tttttcttaa
    69121 tactcgaaac taaacagctt tttcacaacc ccctcagaaa gtctattaaa attcattcac
    69181 aaagaaatcg aataagcgct gttcagatgg atgtacacgg tgggtaagtt ccggatgcca
    69241 ttgaacaccg aggattttat gcatatcatc tttgctttga accgcttcaa tgagtccatc
    69301 gttagaaaaa gcgatggctt ttaataaagg tgaaagatct ttgactgcct gatgatggta
    69361 agaattcaca aaatatggat cggggagaag gttgcttaac aaactgtctg aaacaatctt
    69421 gacttcgtga gtcgtaaatt gcggggcagt gggctgttgt tcatgtttta ctgaccactt
    69481 tggatataat gaaagatctt gataaagtgt accttccaaa acgacattca atagttggag
    69541 tccccggcag actgcaaaaa ttggttttct ttgtttcaat gcttccaaga tcagtgcctg
    69601 ttcaaattgg tctcgttgaa tatttgtttc cgttagcttt ggatgaggat cttccatgta
    69661 aagttgtgga ctgacatctt gaccacctgc aagaataagt ttgtcgattt gtccaatcag
    69721 ttgaggagct gaatctggag acatgactgg cagaataaga ggcaatcctt gagcatctaa
    69781 aactgcatcc acgaatcctt gcggtgtata gctcacttga tttccttgga aagtatctgt
    69841 tgctcgaatc agttgatttc cggcaatgcc gatgattggt ttcatttgta ttccccctaa
    69901 agtagactta ttgtaacaag gatttaaaaa aaattaaact atgtaagact tgcccctata
    69961 cttatctgtt cttgctgtgt tactatctgt aaagagaaat ttcgtgtgaa attcatgacg
    70021 atagttgaaa atattgctta atttgttata ataaaaagta agcagaaata aaaaggttgg
    70081 gcgtaagctt caaggatcta gttcttcaag gggtgagaag gacattttat tgaaggggcc
    70141 tgcctatact aagttatctt tagaggtaca tactttcaat gaaaaaagaa agcatgtacc
    70201 tcttttttaa atcgaaagga agtgaagcaa gtgttagaag ctttggaaca aatccgaaaa
    70261 gcagaagaag aaaatgaaaa gcgtgctcaa acactgcggc agcagctgaa gatctatgca
    70321 acagaaaaag agcaggaatt ggaaacgatc caaacaaact atcgacaaca actaaaacag
    70381 ttggtggaag aaaaagaaca atttgaaata caagaattag aaaaagaaaa aatgaaattg
    70441 aaagcagaag cagacaaggt gcaagcaact ttgaaagatc aatatcaaaa gcatcagagt
    70501 caagcgatcg gtgcgatcat tgaaagggtg aaagaaactt atggccgtca ctaagatgga
    70561 aaaagtgacc ctcatttcag ataaaagaaa tcaggagagg attttacaag cagtacaagg
    70621 aatccaaaac gttgaaatcc gggatctgta tcaaaataga acaaacaacc agtgggtgga
    70681 gaagtatttt ccagatacca cgattattga taaagaagca aaattaagcg ctttaggtaa
    70741 tcggttgaaa gacatccaag aagctatcca attcatacaa caccacggcg atagccgtca
    70801 aaagaaactc catttgaaac gtcaagaact ttccttacaa gatttggaag ccaattattc
    70861 cgaagaaaat ttcataaata aattgaaaga agtccttgat ttaaaagaaa agtgggaaca
    70921 actaactgaa gaacgtgatc gtttagaaga agaggaagaa tggcttcttc attggcaaca
    70981 gctggatatt gctccaagta tgtatgcaag taagacgacc atttttgaga tggggactgt
    71041 gagtgcagca aattttgaaa gtttcaagga agaactgagt aagcttgatg acgtttatat
    71101 ggaagaaata gattatacgc caaaacaagt ttatctttcg tatgttgctt taaaaaaatc
    71161 agttgctgtt atagaagaaa ttgctgggaa atacgggttc aataaagaaa cgtatcctta
    71221 tgaacaaaat cctaaagaaa aactgcaaga gaccaagcag caattatcca ttgttcacga
    71281 gcagcaaaag aagataacga cagcgttagg tcagtgcagt ggctatatcc aagaatttga
    71341 atgggtagaa gaagtcacac ttgccgttgc agaacgagaa aaaataaaag aacggtttat
    71401 ccatgcgact tatctgatcg ttttgcaagg ttgggtagat gcagaagaaa aacagaattt
    71461 gctgcatgtg ttaaacgaaa ccgtatcaga agaagatata tacgtcagtt tcgaaacacc
    71521 aaactcagaa gagattcagc aggaagtccc tactaaattg aaaaaccatc cgcttgtcga
    71581 accttttgaa ttgctgactg aaatgtacag tctgccaaaa tatgaagaag tagatccaac
    71641 accttggatg acaccatttt atcttgtctt cttcgggatg atggtcgcag atgttggtta
    71701 tggtttgctg atgctcattg ggacaatact agctcaaaaa ctacttgttc taccacgcgg
    71761 gatgaaacgt ttcgtaaaat tctttgagat tctctcgata ccatcgatca tctggggatt
    71821 gatctacagt tcatttttcg gacagtcatt accaaaagaa ctgtttggca tccgcttgcc
    71881 tttcccaatc ctatctacga cggatgacgt caatacgatt ttgattttat ccgtgatttt
    71941 cggtctgata cagattttgg ttggattatt tgtggcagca aaggaaaata tcaggagaaa
    72001 agattacttg agtgctgtca gtgatggatt tgcctggcaa gggatcctaa ttgggatcgt
    72061 tattgcgttg gttggtgcca tgttgataaa aaatacagca tttgtttacc ttggcgctgg
    72121 gctatcgatc attgctgcct tatgtatctt gatcgttccg attatccaaa cgccgtctaa
    72181 agtcaaaggt gctgccaaag gtgcgtataa tctttacgga ctgaccggct atatcggtga
    72241 tttagtcagt tatacacgtt tgatggcatt gggtatttca ggcggaagta ttggagcggc
    72301 attcaatatg ctagttgctt tcatgccgcc agctgctcga ttcagtgtag ggatcctttt
    72361 gatcatcgct ttacacgcac tgaatatgtt tttgacactg ctaagtgcct atgtccatgg
    72421 cgcacgattg cagtatgtcg aattttttgg gaagttttat acaggaggcg gacgtgcctt
    72481 tgatccgctg aaaacggcgg aaaaatacgt caacatcaat cacaagaaaa aaaacaataa
    72541 ataattggag gatttttata taatgatgga ttacttaatt agtcaaaatg gtggaatggt
    72601 atttgcggta ttagcgatgg caacagcgac gattttttca gggatcggtt cagctaaagg
    72661 tgttggaatg acaggtgagg cagcagcagc attgacaaca agtcaacccg aaaaattcgg
    72721 gcaggctctg attctgcaat tgcttccagg tacgcaaggt ttgtatggat tcgttattgc
    72781 ctttttgatt tttatcaact taggaaatga catgtcagtt gtacaaggac tgaactttct
    72841 aggtgcttct ctgccgattg cttttacagg cttgttttca ggtattgccc aaggaaaagt
    72901 cgcagcggca ggtattcaaa ttttagcgaa aaaacctgaa catgctacaa aaggaatcat
    72961 ttttgctgcg atggttgaaa catacgcgat tttaggtttc gttatttcct tcctattagt
    73021 gttgaatgcc taagcataaa ggaggaaaag cagatgaacg ccattgaaaa aatcatctct
    73081 cagatgaacg aagcagcaga gcaggaaaga gcggcgttag aacaagaaga gcgaatgaag
    73141 atcgatcaaa actttgaaca aaaacgtacg caagttgaaa cagaacatca aaaacaaaaa
    73201 gaaaaacaaa tcgaattact cgaaaaaaaa taccgtcagc taaggaatcg ccagcaagta
    73261 gaagtacgac aagaaaattt gaatgcgaag caggaatttt taagacgatt gtttgcagat
    73321 gcggtaactg aaatggaaaa ttgggatgaa tctgaacaaa tccagtttat caaaaatgca
    73381 ttgtattcat tacctttgac aggaaaagta gcattcattg ctggagaaaa atcagcagcc
    73441 tatctttctc agacgttgtt ggatgaatgg aacaatgaac ttccctttat gatggtttta
    73501 agtgatgaaa ctgttgctga tcaagcgggt tttctgataa acgatcaagg agttcagtat
    73561 aattttcttt tcagcagcct tgtacaagat atccaaggaa cgatgagttt tgagattgcc
    73621 aatcaattat tcgaataagg agggatcagt gtatggaata ccacgaacta aatcccttga
    73681 ttcgcggaag agagcttgaa cttttgtcca atgagacatt tgaacggatg attcaaacaa
    73741 attctgtcga agcacttggt gaaatattga aatccacgat ttacagtcca tatatttatg
    73801 acggatatga atatgacttc gaacagaatc ttttaaagga gcagagccgt ctatttcgct
    73861 ggttaaagga atcagcaccg gagcctgaaa tcgtttggat ctatacgatg cgttatactt
    73921 tccataatct gaaggttttg acaaaagctg agatgacaaa tcaaaatctg gaccatttgt
    73981 atatcgacga tggattttat tcattagaaa ccttgaagga tgccattcat acgcaagttt
    74041 caaatgaact tcctgaaagc attatggaca gtatacgaga agtacgtgat tattttgaag
    74101 agtctaccat tcttcaggga attgacgtga tttatgatcg acagtttttg acagagcagc
    74161 gacggcttgc cgataagcta ggatatcaag aattgctgac agaagtcatt gcttttattg
    74221 acttgaccaa tatcacaacg atggctcgag gaatattgca gaaaagaaca tatgggttca
    74281 tgacgacggt actttccagc tcgggaagta tcgaaaaaga agtatttttg aactttgtag
    74341 ataaagatat ggaagattac acgaattttc tattagagac agattatgct gattttctgc
    74401 gccctgtcat ccgtgaggga aatattgatc tcgtaaagct tgaacagttg aaagatgatt
    74461 atctaagttc attgtatcaa gaagcacaaa cccaggcttt cggaccactg ccactactag
    74521 cctttttgaa cgcaaaagag gtagaaagca aaaaccttcg tttactggtt atcggcaaaa
    74581 gaagccattt cgaatcagaa acaatcagaa agcgggtgag acaagtctat gacgcataag
    74641 atcggtgtag ttggcgacaa agattctgtt ttgccattca aattgtttgg ctttgatgtt
    74701 cgttatggta caaccaagca aaccgttcgt caggcaattg aagaaatggc aaagaatgag
    74761 tatggcgtga tttatgtcac agagcaatgt gcagcattga gcccagaaac gatcgaacgt
    74821 tacaaggaac aaatgatacc tgctatcgta ttgattccca atcatcaagg atcattaggg
    74881 atagggctgg aagaaattca aaaaaacgta gaaaaagcag taggtcaaaa tatcttatag
    74941 tatgaaaagg agatagaaat tttgcaaatt ggaaaaatca taaaagtctc cggacctctt
    75001 gtaatggctg agaacatgtc tgatgccagt atccaagaca tgtgtctagt gggagatcta
    75061 ggagttatcg gagaaattat cgagatgcgt ggcgatgtgg cgtctattca agtatatgaa
    75121 gagacttctg gaattggtcc aggcgaaccg gttcgctcta ctggtgaagc tttatctgtt
    75181 gaattaggac cagggatcat ttcacaaatg tttgacggaa tccaacggcc attagatacc
    75241 tttatggaaa tcacacaaag taatttctta gggcgcggag ttcaattgcc cgcattggac
    75301 catgagaaaa aatggtggtt cgaaccaaca gtagaagccg gagaaacggt gagtgctgga
    75361 gatgttatcg ggatcgtaga agaaacaaaa gttataaaac ataaaatcat ggtgccaaat
    75421 gggataaaag gaacgatcaa aacaatcgaa aaaggttcat tcactattga tgaaacagta
    75481 tgtgtcattg aaaccgaaaa tggtgacaaa aatttgacga tgcttcaaaa atggccagta
    75541 agacgtagtc ggccaatcaa agaaaaatta aacccggatg cacccatgat cactggacag
    75601 cgagtgattg atacattctt cccagtgaca aaaggaggag cagcagctgt acctggtcct
    75661 tttggtgcag ggaaaacagt cgttcagcat caaattgcaa aatgggccga tgtggacatg
    75721 gttgtctatg tgggatgtgg cgagcgtgga aatgagatga cggatgtttt aaatgaattc
    75781 cctgaattga ttgaccctaa tacaggagaa tcgttgatgg aacgtacggt attgattgct
    75841 aatacatcaa acatgccagt agcagctcga gaagcttcta tctatacggg aatcacaatt
    75901 gcggaatatt tccgtgacat gggttatgac gttgctatca tggcagactc cacttcacga
    75961 tgggcagaag cacttcgtga gatgagcgga cgtttggaag aaatgcctgg tgatgaaggt
    76021 tatccagctt atcttggttc acggcttgcg gaatactatg aacgatctgg aagagtcatt
    76081 gcattaggat cagaaggtcg cgaaggaagt ataaccgcaa tcagtgctgt atccccgtct
    76141 ggaggggata tttcggaacc agtcacacaa aatacattgc gggtcgtaaa agtattctgg
    76201 ggtcttgatt ccagtttagc ccaaaaaaga cattttcctt cgatcgattg gatacaaagc
    76261 tattctcttt attcaacaga agtagggaag tatatggatc atatccttca agctgactgg
    76321 gcatccatgg tcaccgaggg catgcgtatt ttgcaggaag aacagcagct gaatgaaatc
    76381 gtgcgtttgg tagggattga ttccctttca gataatgacc gtctgacatt agaagtggca
    76441 aaatccattc gtgaagatta tttgcagcaa aatgcttttg atgatgtcga tacattcact
    76501 tcaagagaga aacaattcaa aatgttgaag atgatcttga cctttggtga agaaggacgc
    76561 cgtgcgttgt cgttaggtgc ttatttaagt gagatcatgg acggtaccgt atcgattcgt
    76621 gaaaggatcg gacgaagcaa atatatcccg gaaacagaat tagaaaaact agatcaaatt
    76681 attggtgaaa tcaagcaaac gatgcaaacg atcgtttcag aaggaggcat gagcaatgat
    76741 taaagaatat cgtacgatcg gtgaagtcgt cggtccattg atggcggttg aaaaagttgc
    76801 tggtgtcaaa tatgaagaat taatcgaagt ccgtatgcaa aatggcgaga ttcgtcgtgg
    76861 acaagtattg gaagtccaag aagataaagc aatggtccaa atattcgaag gaacaagtgg
    76921 tatcaattta cgtgactctt ctgtacgatt tttaggccat cctttagaac taggtgtatc
    76981 ggaagacatg atcggtcgag tattcgatgg tttgggacga ccgaaagata acggaccaga
    77041 gatcctgcct gaaaagcatt tggatattaa cggagaagta atcaatccag tagctcggga
    77101 ttatccagat gagtttatcc aaacaggtat ctctgcaatc gatcatttga atacattagt
    77161 tcgtgggcaa aaattaccag tattttctgg ctctggtctt cctcataaag aattagctgc
    77221 tcagatcgcg cgacaagcaa cggtactcga ttcatcagat gatttcgccg tagtctttgc
    77281 tgctattgga atcacttttg aagaagctga atttttcatg gaagattttc gtcaaacggg
    77341 cgcaatcgac cgttctgtca tgtttatgaa tttagcaaac gaccctgcaa tcgaacgtat
    77401 cgctactcct cgtatggctt tgactgctgc agaatatctt gcttatgaaa agggaatgca
    77461 tgttttggtt atcatgacag acatgaccaa ctatgcagag gcattgcgag agatttctgc
    77521 agcacggcga gaagttccag gaagaagagg atatcctggg tatctttaca cgaacttagc
    77581 tactttattc gaacgagcag gaagaatccg cggactaaaa ggatcggtta ctcaaattcc
    77641 gattctaaca atgccagaag acgataaaac tcatccaatc cctgacttga ctggttatat
    77701 tacagaagga cagatcatct tgactagaga gctttacaag agtgggattc agccaccaat
    77761 tgatgtactc ccgtctcttt cgcggttaaa agataaggga actggacccg gaaagacaag
    77821 agaagaccat gcagctacga tgaatcagct ttttgcagcc tatgcacaag gaaaacaggc
    77881 aaaagaatta gccgtagttt taggtgaatc tgctttatct gatgtagaca agatctatgc
    77941 gaagtttgct gagcggtttg aaaaagaata tgtcaatcaa ggattctaca cgaaccgttc
    78001 gattactgaa acacttgatc tagggtggga actgctatcg atgttgccaa gaaccgaatt
    78061 aaaacgaatc aaagacgaca tgctggacaa atatctgcca gaagggaagt gagttctgat
    78121 ggcacgattg aatgtgaatc cgacccgcat ggaattgact cgattgaaaa aacagttgac
    78181 aactgccaca agagggcata aattattaaa agataagcaa gatgaactga tgcgtcaatt
    78241 catcctgttg attcgaaaga acaaccagct gcgtcaagaa atggaagagt ctatgacaga
    78301 agcaatgtct gattttgtat tggcaaatgc ttcgatcacg gaacctttca tcgaagaatt
    78361 atttgttttg ccggcggaaa acgttgattt gtctatcgta gacaaaaata tcatgagtgt
    78421 aaaagtacct gtgatgaatt ttgaatatga tgaacagctg acagacacac ctttggaata
    78481 cgggtatttg aattccagtg ccgaactgga tcggtcaatc gatcggttta ctaccctgct
    78541 tccaaaactt ttggaactga cagaaatcga aaaaacttgt caactgatgg cgagtgaaat
    78601 cgaaaagaca cgtcggcgag tcaatgcatt agaatatatg acgatccctc aattagaaga
    78661 aacgatctat tatattcgta tgaagctgga agaaaacgag cgcgcagaag taacaaggtt
    78721 gatcaaagta aaaaatatgg gtaccactga ctaagtggta tcttttttta aaagaggaaa
    78781 acgatgatta aacaaagcaa acaaataaag aaacgtttgc cggctgttca gcttctcgca
    78841 ttaggatttt ttctcctgat tttagttggc ggcggcctac ttaccctacc attttttagt
    78901 aatagtgggc atgggacaaa ttttatcgat gcgcttttca ctgcaacttc tgctgtctgt
    78961 gtaacgggat tgacaacatt gaatacagca gagcattgga acagtgctgg tcaatttttg
    79021 atcatgcttt tgattgagat cggcggtctt ggttttatga tggttccgat tctatgcttt
    79081 gcattgataa agaagaaagt cagtctcagc acacgtatta tattaaaaga agcgctgaat
    79141 ctagaagaag tatcaggtgt gatgaagctc atgctttaca tcctaaaatt ggcctttgtg
    79201 atccaattga ttggtacggt tgctttatct tttgtatttg tgcctgaatt tggctggttg
    79261 aaaggtatct ggtacagttt gttccatgca atctctagtt tttgtaatgc agggtttgat
    79321 ttgttaggag acagtttagc caatcaccag caaaatgttt atttgatcat ggtggtatct
    79381 gctttgatca tttctggtgg gttaggcttc atcgtatggc gtgatttact ggaatatcat
    79441 cagaaaaaga agatgacgat tcattcaaaa atcgcattaa ccgttacagg taccctttta
    79501 ttaggcggat tcgttgtgtt ctttttcaca gagcgcaatg gggcaacgct agtggaaggg
    79561 aatatgtttc aacgattggc aaacaccttt tttatgagtg tgacacctag aacggctgga
    79621 tattattcag ttgattacct ccatatgagc catgcaggtc tgattttaac gatgtttttg
    79681 atgtacatcg gcggaacatc tgggtcgacg gccggcggat tgaaaacaac tacgttaggt
    79741 gtgttgctga tccagatgcg ttcgatgttg aaaggacgta cgagagcgga agcatttggc
    79801 cgtaccatcc gacaaggcgc agtgttgcgg gcacttactt tattttttgt tacgttgacg
    79861 ttgtgtgtag tcgccatcat gattttatcg gtgactgaaa cgatacctaa aacttctggc
    79921 atcgaatata ttgcttttga ggtcttctct gcgtttggta cagtaggtct tacgatggga
    79981 ttgacgccag acttgactgc aatagggaaa ttgatcatta tagcgcttat gtacattgga
    80041 cgagttggtg tattgactgt ggtcttctct ctgatgacaa aagcacaaag aacacaatca
    80101 aaatacaaat atccagaaga aagtgtcatg attggataat ttcatcttct gacagaaacc
    80161 tagtgattta gtaaaataag aaaataaaat aatttttctt gcttcttgga tactttaagt
    80221 gcaaaatgtt cgtttatttt ttgaggcact acccgttgtt gaacctcggg tagtgcctct
    80281 tttttattga aaggaatcaa taagatttga ttcctttatt tatcaatagg ttataattca
    80341 tattttttta ttttttcttt tacgatactt agtccagaag ctaaaatttc aaggttatta
    80401 gaggataggg aaattcgaac gaatgcatct ggttgcgtac gtgtagtaaa gcgtctggaa
    80461 tgataaagtc ggataccgtt agcaagaaag tcattctcaa ttatcttagg gtcaatctca
    80521 ggatcaactg gaagaattcg atagtaaggg acacgattcg ttggtttttc tactttgaaa
    80581 agagaatcaa aaagctgatt ggctcttttt gtaagactta atttagtttc taagatccta
    80641 tttgcttcat ttgaatggag gatttgagtg atgacttcca catctaatcc agaagttttc
    80701 acatttatat taaaaattgc ttgttctatc ttgctttgga catgtactgg aactacaaga
    80761 taagcaactc gcaatccaga acaaataaat tttgtcattc cagctaagta gattgtttgg
    80821 ttaggtaata aattttggaa aggaggaatg atcgtatgtt gatagtaagt tgttaaaaat
    80881 gaatggatat catcttcaat aacccataga ccttcttttt caatcacttc ggctaattgc
    80941 tctcgtcttt tgtgagagat ttgaaaccct ataggattat tacaagaagg cataagaaag
    81001 acaccatgaa tcttcttttt tctacattcc tgaatcaata tatcaggtcg cattccttgc
    81061 tcgtcaaaat caattggaac gatctctaaa tgatataact gagccaattc aatgaaatta
    81121 gcgtatgtat atcggtctgt tgctattcta tcacctggag agaaaagtgc agaaagtgtg
    81181 atagccaatc cattttgaac accggaaaca atagatagag attctaagga cggaatgact
    81241 ccttgagttt ttaaccaatt tgctgcagta gtcaattgaa aatttgtgcc tttgggatct
    81301 tggtaattaa gcaaaccaac aagatttggg ttattactag ttgattgaat aaacgggaca
    81361 acgaatttat tacattcttc aaaagaacta accagaccaa aatcaatgat atgttcggtt
    81421 acttcattgg tagagatggt gatggactca aagacattgg gagaaataaa tgtgccactt
    81481 ccaatattcg tatacagcaa acctttctca attccatatt tataagcctt gccaacggta
    81541 gtaaaattta aatctaaata atcagctagc tctctttggg agggtaactg agtgtttttc
    81601 tgtaatttat tctttaaaat atcttgttct aattgttgaa tcaacgatcg ataataagga
    81661 cgcttcaatt tttgtttgtc tggtcgccaa gttaacgggt aattgtcata agaattaata
    81721 ggcattttct ccactcctta aaattgtata ccatacaatt ttaccattga ttgtattgat
    81781 tttagaagtt aatcttttgt gaggagggaa ttgtctatga aaattattaa ttttgaggaa
    81841 gtagtagctt cttttagttt tgaagaagcg attcaagtaa tgaaaaaatg tttttttgat
    81901 tatgaaagtg gtaaaatcag ccaaaatcct cgattggtgg aaattttacc tgacggaaaa
    81961 ggcaaaaata tgtttgcgat gatgcctgct tatttggggg agaacagata ttttggcaca
    82021 aaagtcatta ccgcttttcc ggataatcat cagtatcatt taccttctca tttaggagag
    82081 attttcttgt ttgatgctca aaacggacta cccaaagcat tgataaacgc aaatgcagtc
    82141 acctggattc gaacagctgc tgtatctgcg ctggcaacag attacttagc aaatccgcat
    82201 gcagaaacac ttgctttaat tggagctggt caacaagcat tgtcgcattt gactgcgatt
    82261 tctaccattc gtcccatcac tacagtgttt gtttacgata ttttagaaga aagacgaaat
    82321 acttttatcg ctaaagctaa aaaacagtat cctaaaataa cgtttataaa tgcaatatca
    82381 gtagaagatg cagtacgtcc agcggaaatc atttgtacgt tgacctctag taaagaggca
    82441 tttcttcaaa aagagtgggt aagggaagac gcacatatca atgctgtggg cacatttact
    82501 cctgatacaa gagagataag tacatcgttg atggaaactt ctcaaatcta tgtagatgat
    82561 tactcagctg ccttaacaga aagcggggac ctgcttatag ccatggcaga aggagattta
    82621 gaggaatctt gtattgttgg tacattaggc gaattagttt ctgagaaaaa aacattttat
    82681 aaaggagaat cgaggccgac gattttcgac gcagttggtc tagctattga agatctttgt
    82741 tgtgcagaat atatttataa caaattagag aaaggggctt taaaatgaac ttagattatt
    82801 acgtagttga tgcatttgca gatgaggtgt tcaaaggaaa tccagcagcg gtttatgtgc
    82861 tagaagaatg gctgccagaa ggtacgatgc aaaaaattgc cattgaaaac aatttatctg
    82921 aaacagcatt tacagtgaag aaaaaccaag aatttgagct tagatggttt acgccagatc
    82981 gagaaatcga tctttgtggt cacgcgacat tagcaacagc atttgtttta tttaactatt
    83041 acaaaatacc tgatgaaacg attaaatttt ctactcaaag cggtaatcta tttgtgacaa
    83101 gaattaaaga ttattattac atggattttc ctagtattat gccgaaaaaa gtgccgatat
    83161 tgtctgaata tgaagaagcg attggggcta agattaaaga agcctactta gcacgtgatt
    83221 tatttttcgt attagaagat gaaaaaacgg tggctaaatt gcagccagat tttacagcta
    83281 tcaaaaattt tgaattagga ataggagtca tcgtgacagc agaaagtgtg caaaaagact
    83341 ttgtttctag aaccttcttt ccaaaattaa caatcaatga agatccagta tgtggatcag
    83401 cacattctaa tcttattcct tattgggcag aaagaatgaa taaaacaaaa ttgtcagctt
    83461 atcaaatgtc atcaaggggc ggggatctag aatgtgaatt aaaagaagat cgtgtgataa
    83521 taggaggaaa agcagttttg ttttctaaag gtacctcgtt tatttgattt ctttcaaatg
    83581 aattaaaaat aaattggtgg agagtggcaa ccttatagct acaatggttg ttaaaaaaag
    83641 acgcaaactt tttcaattta atgaaaagtt tgcgtctcat tttaattatt ggtgtttgtt
    83701 ttttattcaa tcaagagtaa aatgccccat actaactatc ctcggatgac ttcgatttta
    83761 taaccatcag ggtcaatgac aaagtagtaa gaaggcgcag tgccaggtaa tccttttaag
    83821 tcagtaatct caagaccagc agctttatgt tgctcgtgta atttttctag atcatcagct
    83881 gctatagcga tatgaccata gccgtctcct agatcatacg caccatgatc atagttgtaa
    83941 gtcaactcta attcatagtc atccccagga agtgtcaaat aaacaagtgt aaatttgttt
    84001 tctggaaaat cacggcggcg gctttcttca aaaccaaatg ccttttgata aaattcgatt
    84061 gatgcttcaa gatctttcac tcgaacacat gtgtgagcca ttttcataga ttcatctctc
    84121 cttttccttt tactcaatca taacaaaaag aagtaaggaa atagttgatt tgtgcttgtt
    84181 catgagaaat ttctcatgta aaatggatag aaaataaaac tgttaaggtg gaaactattc
    84241 atggataaac caatttttgg tgaaaaaaag caatttgctg attatcaaac ccgttatgca
    84301 gcatatattg tcatagaaag agatcagcag attgcagtaa tcgaggctcc aaatggtgct
    84361 ttttttcttc ctggcgggga aattgaagga gaagagacga aagaagaagc gattgtccgt
    84421 gagctgatag aagaaatggg aattgtggca gaaatttctt cttatctggg agaagctgat
    84481 gagtattttt actcgaatta tcgtgcaact tattattata atccaggata tttctttgtt
    84541 gctgattctt ggaagcgtat aggagaacca actgaaaaga ccaataaaat ttggtgggtg
    84601 agccctcaag aagcgcttgt gaaattgaaa cgtggtagcc accgatgggc agtcgagaga
    84661 tggatcgaaa aaaataaaaa ctgaaagaaa gcgagtagat cagctttctc tcagtttttt
    84721 tatttattac agtacatatt ttttgattgc ttcagctaca ccgtgctcgt cgtttgatga
    84781 agtgatgaca tttgctgctt ctttgacaag agaaacggca tttcccattg ctactcctag
    84841 accagcatat tcaatcatgg ataagtcgtt ctcgttatct ccgatagcca tgatttcatc
    84901 ttgatcaata ccaaggtgct gtgcgagatt cgcaactgcc gcacctttac ttgcttcttt
    84961 atttagtact tcgaagtaat agggcgcact tttgaccgtt gtgtatttat cacggaaagt
    85021 ttgcggtaaa cgcgcaattg ctgcatctaa aatttctggt tcgtcgatca tcatcatttt
    85081 gacgatgttc atgtctggtg tcatttcttc aggtgttcga tattttagcg gcatcttgac
    85141 taaacttgct tcgtggatcg tataagcgct gatatctcga ttaggcgtgt agatcgcttt
    85201 gtcatcgatc gaatggagat gactgccgac acggcgtgcc atcacttcga tctctaggaa
    85261 atcttcatgt gtcagtccgt gacgggcgat gattttacct gatttcgttt gttgtacgag
    85321 tgccccgtta taagtaataa cgtaatcatt atcttgaaaa aggttcaact cgtttaactg
    85381 ttcctggaca cctggtaagg gacggccagt gcataaaacg atcgaaacac cttttgcaac
    85441 agcagcggca atcgcttctt ttacttcttt tgttacttct cttttctcat ttaataaagt
    85501 accatcgatg tcgatagcga ctagtttgat agacataatt tcctccaata tattttaatt
    85561 tatttcaatc aatgcgccat tacggatatg gctggcaaat tcttgataag tttcgtcaaa
    85621 taaatcataa tgatcacgca aggacggatc aaccatttct tttggaaaga aaaatcgctc
    85681 atctccttgt tcttgtcccg ctaatgcagc aacaagctga ctaacctgtg ataattctat
    85741 caaagttccg tcatttcgca aaatctcgat ttgtgtgcga tgtctgcctt gttctgggcg
    85801 ataaaaatca taaggtagat cgtagctaga attcacagca gtgtaataaa caggattata
    85861 tccgaccttt tctactaaca aagtgagttc ttggactaat tttgaatccc ggttgccaga
    85921 aaaagtagca gatttcagtg gtttacgatt caaaaaacgt ttagctaaat catttaaaat
    85981 aggatcagca gattcagacc attgagtaaa gtaagtgccc aagaccccat catcaagttt
    86041 gaggtattct tctaaagtaa agcttccgtc aagaaatggc agaagtaatt gagaatggag
    86101 ttcaaaactg ctggcatctt cttgatacaa ctcgtgtgcg cgatgaagca gatgctccaa
    86161 aattacttcc ataccacggg aaacaggatg gaagtacact tgcacataca tttgatatcg
    86221 gctaacgata taatcttcca ctgcatgcat gccactcatg gaaaaagcga tcccgccttc
    86281 ataaggacga atcacacgta atattcgggt aagatcaaat gttccatatt ctgttccagt
    86341 gaaataagca tcccgaagca aatagtccat tcgatctgca tcgatctgac tagaaatcat
    86401 ttggacaact tgtgggttgg ggtaagtttt ttggatcaca ctagctacct tttcaggaaa
    86461 accttcttct actcggttaa gaatctgata cacttctgtt tctggagaag tgatgatctc
    86521 tacagtgatg gcttcatgat tcgtatggaa gatatgttca aatgtatgag agtaaggacc
    86581 atgaccgaca tcatgcaaca gtgccgcaca taaagtcacc agccgttcct gatcatccca
    86641 gcctccgttg cctatttttt cttttgaaaa atttcgagaa aagatatcgc agattcgtct
    86701 tgaaatctca taaacgccta atgaatgagt aaaacggcta tgttctgctc cgtgaaaagt
    86761 gaaagaagaa gtgcctaatt gtttaatgcg tcgtagacgt tggacttctt tcgaattgat
    86821 caaatctaag attacttgat gctggacatg gatatagtta tggactggat cacgaaaaac
    86881 tttttccata ggcagcattt gatatttata aggggttgtc ataatgtagc tcctttatgt
    86941 tattacgttg ttccattctc tggatttggt tgttccattg ctccagctgg atttcttttt
    87001 ttagccagtc ggtagaatcc tgtaaatcac ttgcagaata cagcttttca aaagcttttg
    87061 caaatgcttc tttgacttct tttacaaaaa ggggttggtc aagcagttct tcaagtgttg
    87121 ccattgtagc aggatccact gcaggatagc catttgtacc aaagtcttct tttaaagcag
    87181 attgataaaa tcgcttcatg acttgcccgc gtttttcctg attaccgttg acacttaagt
    87241 acatcataac agaaatccca tttttgatcc gacgctgagc gataccggca aattttttgc
    87301 catggatgct taaatcataa gttccaggac aataagaatg ggtgatttcg aatgcttgta
    87361 tcggtgcctt tggaaaagcg tatttagtca ataggagcat ttgctcgtaa gcgtcatcta
    87421 tggttatttt ttttgtgtca ctttggggga aaatcaaaga aatattcaaa attccttcat
    87481 ctgatacgat ccctaatcca cctgaatttc tgatcactgg agcgtaacct gcatctttca
    87541 gtgtttggat cccgtcactt agaaaaggag ttcgaacatc cttcatacct aagatgactg
    87601 tgcagtcata ttgccagaaa tgtaaaaaga tttgctggtg ttctttagaa tattccgtta
    87661 atatatctgt taatgcaaaa ggggaaaagt cgtttttttg ataaatgtgc tgatctagtc
    87721 gaatcgcagg gttcattcaa ccggctcctt tgtataaatt catattttct acaatattat
    87781 actctaaaat caaagagttg ttttggaaaa aaggttttct gtaaaaatgg acaagttggt
    87841 tgacaaaaca aaagaaacta ggaacaatgt agctatgaga agtaaaggag aatgaataat
    87901 ggaattatca caaggaacac cgatttcaat caaattgcgt acaaaagtaa aacagcaagg
    87961 ggaagtgcaa gatttttatt ttgatttgaa agggcaaatg gtgacaattg gcgatacgct
    88021 gtacatacgt tataaagaga ttcaggagga gacgggcgat gagattcctg taacgatcaa
    88081 attagttcca gatggtcatg tacagctgat ccgtgcagga gaaatgcgga tgcgtttgaa
    88141 atttggctat aaagaacggt tagaaacatc ctatcgaaca ccatacggta tgatccagat
    88201 tgctactttt acgaaagaac tgcatgttag tttgaaagac cgtcccacag cagggaaggt
    88261 tcgaatcgat tatgatctgt tcatgggacc ggaaaaaatc ggcgaatatt atttgacctt
    88321 ggattttaca gcgtaaatat aaaagaaaag tttgattttt tgtgtctgat tttgtatgat
    88381 aaggagtaga ctgtgaaagg acgtgtcctg attggaaatt agtgtatttg aaggtgcaaa
    88441 caaaagcgaa ttatcaatga tcgaagtagc acacgcgatc ttagaacaac gtggcgatgt
    88501 catggatttt tctgatttag ctaaccagat ccaaaactat cttgggaaat cagacagtga
    88561 aattcgtgat tcactcgcac aattttatac tgacttgaat attgacggca gctttatctc
    88621 attaggggat aatcgttggg gcttgcgttc atggtatgct atcgattcga tcgatgaaga
    88681 agtaaaccat ggaatggacg aagaggatga agatactcca cgtcgccgta aacgcaagaa
    88741 agtcaacgcc tttatcaatg atgatgaaga cgcgatcgat tacaatgacg atgacccaga
    88801 agatacagat ctgacagaag aagatgacga tgatctgttt gatgacgatg atgatgaaga
    88861 tgaagaaatc gctgcttata attctgactt gcaagaaatc ggagcagatg acccgacaga
    88921 tgatgaagaa gacttgccag gaaatatcga agaagattta agtatcatag acgaagacga
    88981 tgatgatgaa gattatgaag aggaagaatt ttctgactct gaaaaagaat aaacattatt
    89041 ttcttacgag aggttgtgac agagacgatc agcctatcag aataaggagg tgtgacacga
    89101 tttttgtcac accttctttt ttgtatataa aaatcccaag taaatacata aaaaataaaa
    89161 aaattgaaac ttttagcgca ccttgtacgt catattaagt gaggcagaaa ggagtggaga
    89221 atgattttta ctggatataa gaaaaaacgg cagatcgaaa aataccgtca cctgctgaat
    89281 ggactcatcg aaactgatta tcaaaaaatg ttccgtatca cgatgaatta cgtacatgat
    89341 aaagaagagg ccttagatgt gatgcaagat agttttcata aagccctgaa ctattttgaa
    89401 aaagaaaaag agatcgagca ttttagtgca tggttttatc ggatattgat ccgcacggca
    89461 ttagatagtt ggcgcagaca aaaaaggacg cctgtggact tatttgaaat tcaagatatc
    89521 ccccaacagt tacctttaga aacttccgtt gcagagctcc atatgatttt agataaaata
    89581 gacagtccgg aaaaagagat tctgatcctc tacttttttg aaggatttcg tttgaaagaa
    89641 attgcgacta tcttggatat gaatgaaaac acagttaaaa cgaaaatgta ccgctcattg
    89701 aatgctttac gtcaaatcct agaatgaagg agagaagagt gccatgtatt cccaaaaaga
    89761 aaatttaaaa aaactaaaga aaacttataa agaacaagca attcccaaag ggcttaaaga
    89821 ggagatccgc cagcgtttta ttatcgaaga gcaatcattt ataaaagcaa agcggagaaa
    89881 gagacgtctc caagggttcg gagtatcttt ggctatcgta atgattacaa caagtagcct
    89941 tctttttaat agtcaagttc gaagctttgc agaagattta cccatcttag gatcagtcat
    90001 tgaattgatc ttaggcgaac gctttactga tcgatctgaa aaaatcgata ttcaggtacc
    90061 gaagatcaat acacaaaatg agaaagaaaa taaaacaatt catggattaa atcaaaaata
    90121 ctttcgcgaa ggacaagcag attttgaaaa agctgaaaaa gaatatggaa attttgaaac
    90181 ggatcattac caagttttgg gagattatca gaaaatcgta gacgataacc ggtttctcgt
    90241 gattgaaagg cagatcaccc aaacagcagc agatagccat gttgaaaaaa gatacgacac
    90301 aatcgacaag aaaaacagtg tccagctctc acttccactt ttattcaaag atgacaccta
    90361 tctatctgtt ttgacaaaag aagtcaaacg gcagatggcc gaacaagtca aggaagatcc
    90421 atctaagtac tattggactg agcaagatat tcaagaaggg acgatagaaa aaccaacact
    90481 tgttacgcct acacgaagtt tttatttgaa caaagagcat caattagttt tgactttttc
    90541 tcaatacgaa attgctcctg gttatatggg tacaccagaa tttgtcattc ctaagtccgt
    90601 gacaaaaacg attttggcat cggaagatta tttggatcat tagacgagaa gtagttgcga
    90661 ctagcagttt caattttcaa gtaagtacaa gtaaataata agaagagaaa aagagaaaga
    90721 agagatatag tgaaaagaaa ttatttagtt atcagtatta ttgctttatc cgtgcttttg
    90781 tttttcgaaa ttacttcggt ggcctccttg atcaccgaag taaaaggaca aacacactct
    90841 tcggagcatt cgtcacaatc tttcaaacaa tcagaacaat caaccattaa aagccaatca
    90901 actgaaacag ctaacgtcaa agaagccatt caagaatcag cggaaaaggt acaaagtcag
    90961 tcatcacaat caacacaaga cagtacaaaa acgagccgag atccggctgt caaaagcgtc
    91021 gcaatcagct ttgatgatgg accaggagcg accacaacac cgcagcttct gcgaatctta
    91081 aaagaaaaaa acgtgcatgc cacttttttc gtcttaggag aaaatacggc gcagcatcct
    91141 gaaatcgtga agcagacagc tgaagcaggg cacgagattg gcaatcacac atacgatcat
    91201 cagaatctgg ccactctttc tgcccagtcg atgacggagg aagtgacgaa agcagacact
    91261 gagatcaaaa aagtcactgg caaaaccccc acttttgttc gtccgcccta tggttctgtc
    91321 acgaatgtag gagcaacgat catccagcga ccgatcatcg aatggtctgt tgattcagaa
    91381 gattggaaga caagaaatcc tgatttgatt ttgcagaaga tccaagcaac agtatacgat
    91441 ggggcaatta ttttattcca tgatatctat cctgaaacga ttcgtgccgt tcctcaagtg
    91501 atcgattatc tgaaagagca agggtatcgc atcacgacag ttggggattt attagggcat
    91561 ccaacggctg tcgagaacta ttatggcaga aacgatcatc ggccagttca gtaagtgaga
    91621 caagtatctt taataaataa cacattttaa taagtagttg aacacataac taccttactt
    91681 gcaaaggctt aacaatatct atacaggtac aacaaaaaac tgtccaccaa ttttctttgg
    91741 cggacagttt tcacttaaaa ataaagaagc aactattcgt aaattatgct aaaatagcag
    91801 tagaacgcgt cctgagggaa tcgaaccccc gtctcaagaa ccggaatctt acgtgatatc
    91861 cactacacta aggacgcaag cactgggata attgtaacta aacagataaa aaattacaag
    91921 gggattggac aaaaaaatga aatttgagca aaatttttca caaaaacagc agcagacaca
    91981 gaaactagcc atgacgcaac agttgcaaca gtccatccaa gttttacaat ataacagtga
    92041 ggagctgttg gcattcgttg agaatcaagc aatggaaaat ccattggtgg aagttgttga
    92101 gccggaatgg cagccagatt acataaaagc ttcttcatct tcttatgaag gagaagagac
    92161 aaattaccta aatcagattc ctgatacaaa agggtcttta tttgattcat tgatcgaaca
    92221 agtccatttg aattaccgag atactttttt gaggaaaatc gttctttatc ttgtagaata
    92281 catcgatttg aacggatttt tgacgattag tttagaagaa gccggaaaag agattggagc
    92341 tacgcctatc caaatgctcg atgcgttgac tctgattcag caattagaac cagctggagt
    92401 aggtgcacgt agtttgcaag aatgtctcat gcttcaaaca gaacgagatg attatgcgcc
    92461 ggaattagct tatatcgtgt tggaagaatg ttttgaggaa ctggtggagc gaaaatggaa
    92521 agaaatcgca caacgttttt ctgttgatct acatgctgtt cagcagatat tcgactattt
    92581 acaaacgttg agtccaagcc ctggccggat tttcgaccgt agcagcgaat tgtacattat
    92641 tcctgatgtc cgggtattag tggacgacga taaaaatgta caagttatct caaaccgaaa
    92701 aaatcagcca aatatacgct ttcaagagag ttacttcaaa caaatgtcac aacaagcaga
    92761 taaagaaact gaaaattatt taaaagaacg gaaacaggaa ttcgaatggt tgaagaaaac
    92821 gatcctacaa cgtggggata caattttgcg ggttgctcaa gtcattgttt cccggcaaaa
    92881 agctttcttt atcgacaagg aacgtccaat caagcctctt acgttaaagg aagttgcaac
    92941 tgagatagat gtgcatgaat ccacggtcag tcgtgcagtc aacgggaaat atttggaaac
    93001 agacttcggt gtatttgaat taaaaaaatt tttcactaca cgaattccta cgaatagtac
    93061 agaacagaca gaagaccttt cagcagatac agcgaagaaa aagctgcagg aattagtcga
    93121 tcaagaagac aaaaacaagc cgttgtctga ccagaaattg gttgaattgc tgaaaaaaga
    93181 tgagatagcg atctcaagac gaacagtagc aaaatatcgt gatttattag gaatcccgag
    93241 ttcatcaaaa agaaaacgtt atgataacta atcagtcaaa agactagaaa aagtatttca
    93301 ctttttctag tctttttagt tgaaaaacga gagcaaaact gttagactta cagtcgtgag
    93361 gttgagattt ccctttattg atgtgaaatt cgaatagtta atttcttttt ttatcgtata
    93421 tgggtcgttt taagtctaca ttggacgtaa agtgtccaac taaggagatc gctatgctgg
    93481 atgaaataaa aatgattgaa tctgttgcac cagatattat cgaagtgttg caagaacgct
    93541 ataaaatttt acgaaatatc tattggatgc agccgattgg acgtcgaagt ttatcggaaa
    93601 gtatggggat cacagaacga gtattgcgaa cagaaacaga tcttttgaaa aatctgaatt
    93661 tgatcgacac ctcaaaaagc ggtatgacgc tgacaactaa gggcgaagaa gtttatcaaa
    93721 gccttgaaaa cttcatggat cagcttttag gtacgcatca aaccgaacaa cagttggcag
    93781 aatattttgg taaccaacgc tgtatcgttg tttcaggaaa cagcgaagag cagaccaaag
    93841 tggctgatgc attcggcgaa gcgctgagcg aagccctaga ccgactactt ccagaaggcg
    93901 agaatatcat cgctgtgatg ggaggaacta ctatggctgt ggtagccgaa caattgtcta
    93961 atctggaaaa taagaaacgg cataacctgt ttgtccctgc aagaggcggg attggtgaag
    94021 cgataactgt acaggcaaat tctgtcagtg caagaatggc tgctaaagca aacggtaacc
    94081 accgtgcact ttatgttccg gaacaattaa gtctggcaac ttacaattct ttactcaatg
    94141 agccatctat ccaagaagtc ttaaacttga ttagtgaagc gaattgtgtt attcatagta
    94201 ttgggcgtgc attacacatg gcagcacgtc gtaagatgac tgaaaaagaa ttagtcatgc
    94261 tgaaacaagc aaatgctgtt gcggaatctt ttggctactt tttcaatgaa aaaggtgaag
    94321 tcgtttataa ggtccctaga atcggcatag aattgcaaga tttggaaaaa gtcccgatca
    94381 tcatggcaat cgcgggcgga aaatcaaaag ctaaagcaat tcgagcttat atgaaaaatg
    94441 caccaaaaca aacgtggctc atcactgatg aagctgctgc aaatgagatt ttaaaagggg
    94501 taacccttta aaataaatat ttttttgatt ttcataagga ggaaatctta aatgacagtt
    94561 aaagtaggta ttaatggttt tggacgtatt ggacgtctag cattccgtcg tatccaagat
    94621 gtagatggaa tcgaagtagt agcaatcaac gacttgacag atgctaaaat gttggcacac
    94681 ttgttaaaat acgacacaac tcaaggacgt ttcaacggaa cagttgaagt tcatgaaggt
    94741 tcattcaacg taaacggaaa agaagttaaa gtattagcta accgcaaccc agaagaatta
    94801 ccatggggcg aactaggcgt agatatcgtt ctagaatgta ctggtttctt cacttctaaa
    94861 tcagcagctg aaaaacattt aacagctggt gctaaacgcg ttgttatctc tgctcctggc
    94921 ggaaacgatg ttccaacaat cgtttataac acaaaccacg aaacattaac tggtaaagaa
    94981 acagttatct caggtgcttc atgtactact aactgtttag ctcctatggc taaaacattg
    95041 aacgacaaat ttggtgttgt tgaaggatta atgacaacta tccacgctta cacaggtgac
    95101 caaatgactc tagacggacc tcatcctaaa ggtgacttcc gccgtgcacg cgctgctgct
    95161 gcaaacatcg ttcctaactc aacaggtgct gctaaagcta tcggtttagt aattcctgaa
    95221 ttgaacggta aattagacgg agctgctcaa cgtgttcctg taccaacagg ttcattaaca
    95281 gaattagtaa cagttcttga aaaagaagta actgttgacg aaatcaatgc agcaatgaaa
    95341 gaagcttcaa acgaatctta cggatacaac acagacgaaa tcgtttcttc agatatcgtt
    95401 ggtatgactt acggttcatt atttgatgct acacaaacta aagtaatgac agttggcgac
    95461 aaacaattag ttaaaactgt tgcttggtac gacaacgaaa tgtcatacac tgcacaatta
    95521 gtacgtactt tagaatactt cgctaactta taagatagac aaacgtacaa gtgtaaatta
    95581 tagacatgta catttaaaag cggggaagca atcgcgcttc ttccgctttt tttgataata
    95641 agtttattca ggaggaaata aaatggctaa gaaaacagtg aaagatatcg atttaaaaga
    95701 caaaaaagtt cttgtccgtg ttgacttcaa cgttcctttg aaagacggcg tgatcactga
    95761 cgacactcgt atcaaagcag cattgccaac aatcaactac gttctagaac aaggcggaaa
    95821 agcaatcctt ttctctcacc ttggacgtgt aaaaacagaa gaagataaag aaggaaaatc
    95881 tttagctcca gttgcaaaac gtctaggcga attattaggt aaagaagtaa cattcgtacc
    95941 tgaaactcgc ggagaacaat tagaagaagc aatccgcaac atgaatgacg gcgacgttgt
    96001 cgtattcgaa aatacacgat ttgaagatat tgacggtaaa aaagaaagca aaaatgatac
    96061 agaactaggt aaatactggg cttcattagg cgatgtattt gttaacgatg ctttcggtac
    96121 agctcaccgt gcacatgctt ctaacgtagg tatcgcttca actggtatcc caacagttgc
    96181 tggattcttg atggaaaaag aaatcaagtt catcggtgaa gcagtagaag aaccaaaacg
    96241 accaatgatt gcaatccttg gtggcgcaaa agtttctgat aaaatcggcg taatcgaaaa
    96301 cttgattcct aaagcagata aaatcttgat cggtggcgga atgacttaca cattctacga
    96361 agcaaaagga atcaagatcg gtaactctct agtagaagct gataaagtgg aactagcaaa
    96421 agaattaatc gaaaaagcag gcgacaaact tgtcttgcca atcgacaatg tctgtgcacc
    96481 agaattttca aatgatgttg aaacacaagt aatcgaagga gacattcctg atggtttgat
    96541 ggctttagac atcggcccag catcagtaaa attatttgct gatacattac aaggtgcaaa
    96601 aacagttgtt tggaacggac ctatgggtgt atttgaaatg agtaactttg ctaaaggtac
    96661 aatcggtgtt tgtgaagcaa tcgctaactt agaaggcgca acaacaatca tcggtggcgg
    96721 agactcagcc gcagcagcag aacaattagg atttgctgac aaattcacac acatctcaac
    96781 aggtggcggc gcaagcttgg aattgcttga aggtaaagaa ttaccaggac tagcagcaat
    96841 caacgataaa taaacgacca agtttgctca attctgacga gtaatcgaac aaaaggtgaa
    96901 gggagttttc atgactccct agccattttt caataaatta aggagtgtgt tcctcaatgc
    96961 gtaaacctat tatcgcaggt aactggaaaa tgaacaaaac tgcatcagaa gcaaaagaat
    97021 ttgctgaagc agtaaaaaac aaaatccctt caaatgacaa agttgattca gtcatcggat
    97081 ctcctgcatt attcttacaa gaattaatga catcagctga aggtacagaa ctaaaaatct
    97141 cagcacaaaa ctgctactgg gaaaactcag gtgcgttcac tggtgaaact tcaccagcag
    97201 ctcttgctga tctaggtgtt cattatgtga tcatcggaca ttcagaacgt cgtgaatatt
    97261 tccatgaaac agacgaagac atcaataaaa aagcgaaagc tatctttgca aatggtatga
    97321 caccaatcct atgctgtggc gaatctttag aaacctatga agcaggcaaa actgctgaat
    97381 ggatcgaagg acaaattaca gctggtttag ctgatctttc agctgaacag gtgtcaaaca
    97441 tggttattgc ttatgaacca atctgggcaa tcggtactgg taaatcagct gacgcacaaa
    97501 tcgctgacga aatttgtgga gttgtacgtc aaacagttga aaaactttat ggaaaagaag
    97561 tatcagaagc agttcgtatc caatacggcg gttctgtaaa accagaaaat attgctgaat
    97621 acatggcaaa agaaaatgtt gacggtgctt tagtcggtgg cgcaagcttg caagcagatt
    97681 cattcttgtc attgttagac gctgtaaaat aattgttgaa aatttgcgaa aaatgcaaga
    97741 aatgtttgca ctaatgagca aaattaacta aaatcgtata tgagggaaat cccttaggaa
    97801 aaaacaaact caaaggagag acaaaacatg tcaattatta ctgatgttta cgctcgcgag
    97861 atcttagact cacgtggtaa cccaacaatc gaagtagaag tatacacaga aagcggagct
    97921 tttggccgcg gaatggttcc ttcaggtgct tcaactggtg aatacgaagc agttgaatta
    97981 cgtgacggag acaaagctcg ttatggcggt aaaggtgtaa ctaaagctgt cgacaacgta
    98041 aacaacatca ttgctgaagc aatcattggc tacgatgttc gtgaccaaat ggctatcgac
    98101 aaagctatga tcgctttaga cggaactcct aacaaaggta aattaggtgc gaacgctatt
    98161 ttaggtgttt ctatcgctgt tgcacgtgca gctgctgact acctagaagt acctttatac
    98221 cactacctag gcggattcaa cacaaaagta ttgccaacac caatgatgaa catcatcaac
    98281 ggcggatcac atgctgataa ctcaatcgac ttccaagaat tcatgatcat gcctgttggc
    98341 gctccaacat tcaaagaagc tctacgtatg ggtgctgaag tattccacgc attagcttca
    98401 atcttgaaag ctcgcggatt agcaacttct gttggtgacg aaggtggatt tgctccaaac
    98461 cttggttcaa acgaagaagg ttttgaagta atcatcgaag caatcgaaaa agctggctat
    98521 gtacctggta aagacgttgt tcttgctatg gatgctgctt cttcagaatt ctacgacaaa
    98581 gaaaaaggtg tttacgtact agctgattca ggcgaaggcg aaaaaacaac tgacgaaatg
    98641 atcaaattct acgaagaatt agtttctaaa tatccaatca tctcaatcga agacggatta
    98701 gacgaaaacg actgggacgg attcaagaaa ttaactgacg tattaggcga caaagttcaa
    98761 ttagttggtg acgacttgtt cgtaacaaac actcaaaaat tatctgaagg tatcgaaaaa
    98821 ggaattgcta actcaatcct tatcaaagtg aaccaaatcg gtacattaac agaaactttc
    98881 gaagctatcg aaatggctaa agaagctggc tacacagcag ttgtatctca ccgttctggt
    98941 gaaacagaag attcaacaat ctctgatatc gctgttgcaa caaacgctgg ccaaatcaaa
    99001 actggttctc tatcacgtac tgaccgtatt gctaaataca accaattact acgtatcgaa
    99061 gaccaacttg gtgaagttgc agaatacaaa ggtttgaaat ctttctacaa cttaaaaaac
    99121 aaataattct tttctaatga agatacatga tcgactattg aaagatagtc gagtatgatc
    99181 acttagttaa gtaatcgaac tctctacttg ctgaaatatc agcaggtaga gagttttttt
    99241 gcaactagct tctgtatatg atgtttacaa agaatggtac aagaaaagat catccttgaa
    99301 aaaggaaagc taacaataac tagcatcata taagagcttt taaggataga acagtagaat
    99361 aggaatctat gagcaagtcc tctcgtataa ataaaatagg agggaagtag cagcatattt
    99421 ttcataaagt ggctctcttt cttcattttt actttggttg ctcctatttg aaaattcgag
    99481 cacactcaaa tacaataaaa agaaatggca agggagagga ttagatgaaa aaagaagaaa
    99541 aaatcgcgat tttacaagag atcatccgaa ttaaatcagt gaatggaaac gaaggtgaag
    99601 tagcagccta tttgaataag cttttggcaa agcatgacat aacaggagag attgtttctt
    99661 acagagatgg tagagataat ttgattgctc gttaccaaaa gggccaatca ggaaaagtgt
    99721 taggcctatc tgggcatatg gatgtcgtgg cggctggtga tgaatcgtct tggacctatg
    99781 caccctttgc agcagaaatc catgggaacc gtttgtacgg acgtggtgct acagatatga
    99841 agagtggctt ggcagcaatg gtgattgcca tgatcgaact gaaagagtca ggaaaaccat
    99901 ttaacggaac agtcaaatta ttagccactg tcggagaaga agtgggtgaa ctaggtgggg
    99961 aacagctcac gaaagcaggc tatgtagatg acttagatgc cttgatcatc ggagagccaa
   100021 ccaattacag tttgatgtat acgcacatgg gatcaatcaa ctatacagtc acctcgcacg
   100081 gaaaagaagc gcatagctct atgccagacc aaggttataa tgcaatcaat cacctaaatg
   100141 aattcattac gaaagcaaat gctgaaatga atcacctcgc tgaaacaatc gagaatcctg
   100201 tcctaggaaa aacaatccat aatgttacat tgatcagtgg cgggaatcaa gtcaacagca
   100261 tcccaagcca tgcgcagctc caagggaaca ttcgatcgat tccagaatac ccaaatgata
   100321 aaatcattgc attgctgcaa tcaatcgtca atgaattgaa tcaagagaca gactatcatt
   100381 tggaattgat gatcgattac aacaaaatac ctgtcaaagc tgatccagat tctcctttga
   100441 ttcattgcat tcagcaacaa ttcagccagc cattaccttt agttggagcg gcagcaacaa
   100501 cggatgcagc cgaatttacg aaagctaacc attccttcga ctttgtcgtc tttgggcctg
   100561 gtgtcgttac tttgcctcat caagtagatg agtatgttga aatcgataat tatttggata
   100621 tgatcgaaaa atatcaagga attattttat cctacttagc gtaagatttt tttaataaat
   100681 gaaaaaacag agccagatta gcatta
//
LOCUS       DADGKS010000002        84664 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.002, whole genome shotgun sequence.
ACCESSION   DADGKS010000002 DADGKS010000000
VERSION     DADGKS010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 84664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.002"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(59..187)
                     /locus_tag="JXV47_000102"
     CDS             complement(59..187)
                     /locus_tag="JXV47_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAX1486179.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="JXV47_000103"
     CDS             complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="JXV47_000103"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAX1486180.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(1674..2729)
                     /locus_tag="JXV47_000104"
     CDS             complement(1674..2729)
                     /locus_tag="JXV47_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAX1486181.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="JXV47_000105"
     CDS             complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="JXV47_000105"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HAX1486182.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="JXV47_000106"
     CDS             complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="JXV47_000106"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HAX1486183.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="JXV47_000107"
     CDS             complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="JXV47_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HAX1486184.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="JXV47_000108"
     CDS             complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="JXV47_000108"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HAX1486185.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="JXV47_000109"
     CDS             complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="JXV47_000109"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HAX1486186.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            10491..12050
                     /locus_tag="JXV47_000110"
     CDS             10491..12050
                     /locus_tag="JXV47_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HAX1486187.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(12161..14092)
                     /locus_tag="JXV47_000111"
     CDS             complement(12161..14092)
                     /locus_tag="JXV47_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAX1486188.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="JXV47_000112"
     CDS             complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="JXV47_000112"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAX1486189.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(15021..15773)
                     /locus_tag="JXV47_000113"
     CDS             complement(15021..15773)
                     /locus_tag="JXV47_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAX1486190.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(15932..16141)
                     /locus_tag="JXV47_000114"
     CDS             complement(15932..16141)
                     /locus_tag="JXV47_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486191.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(16152..17480)
                     /locus_tag="JXV47_000115"
     CDS             complement(16152..17480)
                     /locus_tag="JXV47_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486192.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            complement(17845..18432)
                     /locus_tag="JXV47_000116"
     CDS             complement(17845..18432)
                     /locus_tag="JXV47_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HAX1486193.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="JXV47_000117"
     CDS             complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="JXV47_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HAX1486194.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(20012..21301)
                     /locus_tag="JXV47_000118"
     CDS             complement(20012..21301)
                     /locus_tag="JXV47_000118"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HAX1486195.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(21455..22387)
                     /locus_tag="JXV47_000119"
     CDS             complement(21455..22387)
                     /locus_tag="JXV47_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486196.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(22544..23203)
                     /locus_tag="JXV47_000120"
     CDS             complement(22544..23203)
                     /locus_tag="JXV47_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HAX1486197.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="JXV47_000121"
     CDS             complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="JXV47_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HAX1486198.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGASGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(24244..24534)
                     /locus_tag="JXV47_000122"
     CDS             complement(24244..24534)
                     /locus_tag="JXV47_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486199.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            24944..26749
                     /gene="glmS"
                     /locus_tag="JXV47_000123"
     CDS             24944..26749
                     /gene="glmS"
                     /locus_tag="JXV47_000123"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HAX1486200.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(26821..28176)
                     /locus_tag="JXV47_000124"
     CDS             complement(26821..28176)
                     /locus_tag="JXV47_000124"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HAX1486201.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(28200..29369)
                     /locus_tag="JXV47_000125"
     CDS             complement(28200..29369)
                     /locus_tag="JXV47_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486202.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(29366..30253)
                     /locus_tag="JXV47_000126"
     CDS             complement(29366..30253)
                     /locus_tag="JXV47_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HAX1486203.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="JXV47_000127"
     CDS             complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="JXV47_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HAX1486204.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            34320..34841
                     /locus_tag="JXV47_000128"
     CDS             34320..34841
                     /locus_tag="JXV47_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAX1486205.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(35540..36105)
                     /locus_tag="JXV47_000129"
                     /pseudo
     CDS             complement(35540..36105)
                     /locus_tag="JXV47_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36284..36940)
                     /locus_tag="JXV47_000130"
     CDS             complement(36284..36940)
                     /locus_tag="JXV47_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486206.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="JXV47_000131"
     CDS             complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="JXV47_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HAX1486207.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(38477..39475)
                     /locus_tag="JXV47_000132"
     CDS             complement(38477..39475)
                     /locus_tag="JXV47_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HAX1486208.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="JXV47_000133"
     CDS             complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="JXV47_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HAX1486209.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(40491..41222)
                     /locus_tag="JXV47_000134"
     CDS             complement(40491..41222)
                     /locus_tag="JXV47_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HAX1486210.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            complement(41226..42491)
                     /locus_tag="JXV47_000135"
     CDS             complement(41226..42491)
                     /locus_tag="JXV47_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HAX1486211.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="JXV47_000136"
     CDS             complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="JXV47_000136"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HAX1486212.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="JXV47_000137"
     CDS             complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="JXV47_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HAX1486213.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            47833..49335
                     /locus_tag="JXV47_000138"
     CDS             47833..49335
                     /locus_tag="JXV47_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAX1486214.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            49337..50074
                     /locus_tag="JXV47_000139"
     CDS             49337..50074
                     /locus_tag="JXV47_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAX1486215.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(50119..50292)
                     /locus_tag="JXV47_000140"
     CDS             complement(50119..50292)
                     /locus_tag="JXV47_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAX1486216.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            50268..50933
                     /locus_tag="JXV47_000141"
     CDS             50268..50933
                     /locus_tag="JXV47_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar diacid utilization regulator"
                     /protein_id="HAX1486217.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            complement(51015..52181)
                     /gene="dnaJ"
                     /locus_tag="JXV47_000142"
     CDS             complement(51015..52181)
                     /gene="dnaJ"
                     /locus_tag="JXV47_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HAX1486218.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(52332..54161)
                     /gene="dnaK"
                     /locus_tag="JXV47_000143"
     CDS             complement(52332..54161)
                     /gene="dnaK"
                     /locus_tag="JXV47_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HAX1486219.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(54212..54775)
                     /gene="grpE"
                     /locus_tag="JXV47_000144"
     CDS             complement(54212..54775)
                     /gene="grpE"
                     /locus_tag="JXV47_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HAX1486220.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(54869..55912)
                     /gene="hrcA"
                     /locus_tag="JXV47_000145"
     CDS             complement(54869..55912)
                     /gene="hrcA"
                     /locus_tag="JXV47_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HAX1486221.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(56146..57312)
                     /locus_tag="JXV47_000146"
     CDS             complement(56146..57312)
                     /locus_tag="JXV47_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HAX1486222.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNAHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            complement(57328..57555)
                     /locus_tag="JXV47_000147"
     CDS             complement(57328..57555)
                     /locus_tag="JXV47_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HAX1486223.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            58039..58629
                     /locus_tag="JXV47_000148"
     CDS             58039..58629
                     /locus_tag="JXV47_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HAX1486224.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            58819..59532
                     /locus_tag="JXV47_000149"
     CDS             58819..59532
                     /locus_tag="JXV47_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486225.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(59647..60657)
                     /locus_tag="JXV47_000150"
     CDS             complement(59647..60657)
                     /locus_tag="JXV47_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HAX1486226.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(60694..61176)
                     /locus_tag="JXV47_000151"
     CDS             complement(60694..61176)
                     /locus_tag="JXV47_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HAX1486227.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            61326..61694
                     /locus_tag="JXV47_000152"
     CDS             61326..61694
                     /locus_tag="JXV47_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chaperone"
                     /protein_id="HAX1486228.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            62159..62611
                     /locus_tag="JXV47_000153"
     CDS             62159..62611
                     /locus_tag="JXV47_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1486229.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(62735..63586)
                     /locus_tag="JXV47_000154"
     CDS             complement(62735..63586)
                     /locus_tag="JXV47_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HAX1486230.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(63599..64384)
                     /locus_tag="JXV47_000155"
     CDS             complement(63599..64384)
                     /locus_tag="JXV47_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAX1486231.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            complement(64736..65677)
                     /gene="ribF"
                     /locus_tag="JXV47_000156"
     CDS             complement(64736..65677)
                     /gene="ribF"
                     /locus_tag="JXV47_000156"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HAX1486232.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            complement(65681..66604)
                     /gene="truB"
                     /locus_tag="JXV47_000157"
     CDS             complement(65681..66604)
                     /gene="truB"
                     /locus_tag="JXV47_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HAX1486233.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            complement(66972..69334)
                     /locus_tag="JXV47_000158"
                     /pseudo
     CDS             complement(66972..69334)
                     /locus_tag="JXV47_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            69782..69955
                     /locus_tag="JXV47_000159"
     CDS             69782..69955
                     /locus_tag="JXV47_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1486234.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            complement(70112..70459)
                     /gene="rbfA"
                     /locus_tag="JXV47_000160"
     CDS             complement(70112..70459)
                     /gene="rbfA"
                     /locus_tag="JXV47_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HAX1486235.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(70486..72792)
                     /gene="infB"
                     /locus_tag="JXV47_000161"
     CDS             complement(70486..72792)
                     /gene="infB"
                     /locus_tag="JXV47_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HAX1486236.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(72805..73116)
                     /locus_tag="JXV47_000162"
     CDS             complement(72805..73116)
                     /locus_tag="JXV47_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HAX1486237.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(73113..73406)
                     /locus_tag="JXV47_000163"
     CDS             complement(73113..73406)
                     /locus_tag="JXV47_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HAX1486238.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(73428..74603)
                     /gene="nusA"
                     /locus_tag="JXV47_000164"
     CDS             complement(73428..74603)
                     /gene="nusA"
                     /locus_tag="JXV47_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HAX1486239.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(74626..75099)
                     /gene="rimP"
                     /locus_tag="JXV47_000165"
     CDS             complement(74626..75099)
                     /gene="rimP"
                     /locus_tag="JXV47_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HAX1486240.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(75244..79602)
                     /locus_tag="JXV47_000166"
     CDS             complement(75244..79602)
                     /locus_tag="JXV47_000166"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HAX1486241.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            complement(79814..81523)
                     /locus_tag="JXV47_000167"
     CDS             complement(79814..81523)
                     /locus_tag="JXV47_000167"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HAX1486242.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            complement(81591..82859)
                     /gene="rseP"
                     /locus_tag="JXV47_000168"
     CDS             complement(81591..82859)
                     /gene="rseP"
                     /locus_tag="JXV47_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HAX1486243.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(83020..83820)
                     /locus_tag="JXV47_000169"
     CDS             complement(83020..83820)
                     /locus_tag="JXV47_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HAX1486244.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(83817..84629)
                     /locus_tag="JXV47_000170"
     CDS             complement(83817..84629)
                     /locus_tag="JXV47_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HAX1486245.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
BASE COUNT        23259 a        18317 c        14779 g        28309 t
ORIGIN      
        1 taaaaagact aagaaacaat aacaaaagtt aacacttctt agtctttctt tagcacgtct
       61 atttattaaa gattttaggg ccttttctca tgtttttacg atcattctta ggtgtttcca
      121 tttgtttgga tcggcctcca ccttgtttct ttttgatcaa ttctttcatt ttttcttttt
      181 ggtccatttt tattctcctt taacgaatga agcgactaat tcgatatgat gggtttgcgg
      241 gaaaagatct acaggctgaa ctttcttcac ggcataacct gcttctgcaa ataacttagc
      301 atctcttgca aaagttgccg gattacatga gatatagacg attcgttctg gtgacatttc
      361 gattgctgat tcaataaaat gatgatctaa tccttttcgt ggagggtcaa ctacgatcac
      421 agatggtttg atcccttttt cttgccattt tttcataact ttttctgctt ttccgacttc
      481 ataatgaaca ttttcgattt tattatttaa agcattgaac tgtgcatctt caattgcttc
      541 tggaataact tccatcccat acaccttatc cactctgtct gctaaagaca agccaatcgt
      601 acctattcct gaataagcgt cgatcacaat gtctttttta tctaactcgg caaactcgat
      661 ggctgtttgg tacagatact ctgcttgttg agtatttact tgataaaatg actttgctga
      721 gattcgatag gtttttccta atagctgatc ttcgatatag tctctgccat ataaaacttt
      781 ttctttgtct cctaaaatca catttgtttt ttcttcattg atattttgga tgaccgaaac
      841 cacttctggc aattcttcat gaatagcttc agcaatttcc ttggatttaa agaatttttc
      901 tttacgagta actaaaacga ccatcatttc atgggaataa tgaccacgac ggataatgat
      961 gtgacgaagc tgtccttcat ttttttcttc attatatcct cgtacttgga accgttgcaa
     1021 gatatctctg actactttga ttgcttgatc gatgacagga tcttggatat aaaaatcttc
     1081 gatagggact agatcatggc tattcttttt gtaaaaaccg gtggctaact gtccatcgat
     1141 acggcgaaca gggatctgtg ctttattacg gtagccgaat ggttctgcca ttccgaccgt
     1201 tggaagtaca ggaacttctg gcatcttagc aatcttcgcc attacatgct ctacttgttt
     1261 ttgtttgaag acaagctgtt gttcatactt caaatgggct aaaggtgcga tacctatgcg
     1321 aagtaatgca ttgttttcta caggctgacg atcaggtgat tgtgtaataa atgtttcgac
     1381 ttttccatat ccaaacttat tgcctgcttt tactactagt atttctactt cttctccagg
     1441 gagtgcattt tcgataaata atggataacc atcgattttt gctaccccca ttccttcata
     1501 actcaagtcg acgatttcga ctgtatatcg ttcgtttttc tttactattt gctgttctgt
     1561 catattttgc tcctttaagc ctatttttca atcctactga actctactat aaatcagcta
     1621 attacacaac taaaaccggc actgacctta ctacgttcag caccggcttt tgattaattc
     1681 ttttgattag gtgtttcgtc tgctattttt ccgtcaccgt cgatatcttc atccgttaaa
     1741 cgttcgactt cttttacgaa ttctttgctg acaacctcta attcttcttc atctgtacct
     1801 gtgattgctt catcaggaat ctgatcggta ttggcaaaga actcaatgtg ttgatgaaga
     1861 ttttggaaat gcatcggtgc ttccccgccg tattcaccat ctaagttgat cattactggt
     1921 cgattgatat catcttctgt ttcaacgaac aaactgcttg ttttggtata gattattctt
     1981 ggatcatcga catgtcgacc gccattcagc atgagtgctg caatatgcaa gatctcaaag
     2041 atatttgctg tcttcacaat gattaaagaa aacttcccat catccaattt ggcatctggc
     2101 gcgatctgtt cgaatcctcc aacagagttc gtcagcccta ggaaaaacat cgaagcattt
     2161 ccgatatatt ccccttcatc atacttcaag cgcattttga ttggctttac tcgagggagc
     2221 atctctgctc ctttcgcaag ataagcaaga taaccaaaaa tactctttag ttctgatgga
     2281 acttcataag tcaattctgt caaatagcca cctgcagcga tattgatgaa gtaactgtta
     2341 tcagaaaggc cgatgtccat ttttacggtt tggtgttttt ttatcacttc tgctgctgct
     2401 ttaatattat ctctaggaat ttttaatgct cgagcatagt cgttcgttgt accagctggg
     2461 atgatggcca ttttaggacg gtgttcaagc ggagcgattc cattaaccac ttcgttgatt
     2521 gtgccatcgc caccagctgc cactactaga tcaaaaccta gttctgcgac tctacatgct
     2581 tcattcttgg ctgaatctgg ttctggtgta gttgcatagg cgctggcttc aaatcctgct
     2641 tcttctaatg cctgtaggat atccgccaaa ttttttttca ataattcttt tcccgaggtg
     2701 gggttataaa ttacgcgtgc ttttttcatt ttcagcctct atcgtttcgc taattcatct
     2761 ttaagtagct tattcacgac accaggattt gcttgtcctt tagttgcttt catgatttga
     2821 ccgactagga agccaaccgc acgatctttt ccatttttga aatcatcgac agattgttgg
     2881 ttgttatcca aaatttcatt aatgattggc agtagtttgt tcggatcaga taattgcacc
     2941 caaccatttt tttcaactac ttcttgggct tctccgccat ttgtgatcaa ttcacggaag
     3001 acttttttgg cgatttttga gctgatcgtt ccatcggcga tcaaacgaat cattcctgct
     3061 aagttctcag gtgtcaattt tgtctcagct aattccagtt tctcactgtt caagtaagca
     3121 gaaacttcac ccatcaacca gttagatgct tgcttggcat ctgcaccatt ttccaaaaca
     3181 gcttcaaaaa aatcagacat ttcttttgta agtgtcaata ccattgcgtc atactctgga
     3241 agtccaaact cacggatata gcgttcgcga cgagaagctg gcatctcagg caaactagct
     3301 tttacttttt gaatccattc gtcatcgatc acgaatttcg ggatatcagg ctctgggaag
     3361 taacgataat cactagaccc ttctttgaca cgcatcaaaa ctgttttatt cgttgtttcg
     3421 tcaaaacggc gtgtttcttg ttggatttct cctcctgaaa gaagaacttt tgcttgacgt
     3481 ttttcttcaa aagctaaacc ttttttcacg aaagataaag agttcaagtt tttcaattct
     3541 gctttcgtac cgaactcttc ttgtccataa gggcgaagag aaatattggc atcacagcgc
     3601 atagagcctt cttccatttt cacatcgctg acttctgtaa attggataat tgatcgcaat
     3661 gcttctagat aagcgtatgc ttcttctggt gaacgcatat cagcttcaga aacgatttcg
     3721 atcaaaggcg tgccttgtcg gttcaaatca acgtaagaat aaccgccaat accatgcatg
     3781 ttttttccag catcttcttc taaatggaca cgttcgatcc ggattttttt ctttttacct
     3841 tctacttcga tttcgatcca tccgtcatga ccgattggtt gatcaaattg ggaaatttga
     3901 tatgcttttg gattatctgg gtaaaagtaa tttttccggt caaaatgagt atctttagag
     3961 atttcacagt ttaatgccaa agctgctttc atcccgaatt ccagcgcagc tttattcatt
     4021 actggcagca cgcctggata accccagtcg atcacgtttg tattgctgtt tggttctgca
     4081 ccaaaatgag ctggcgctgg agagaaaatt tttgagttgg tttttaactc gacgtggact
     4141 tctagtccaa tgactgtttc aaaattcatt cgtctttccc tcctaaaata gctggttgtt
     4201 gtttatggaa ttctgttgct tgttcaaacg catatgccgc ttgatacatc gttttttcat
     4261 caaaataatt accgatgatc tgcaatccaa ctggtaatcc ttctgataaa cctgccggta
     4321 cagacatacc tggaagtcca gccaagttga cagggatcgt taagatgtca ctcatgtaca
     4381 ttgtgattgg atcgttaatg ttctcaccga ttccgaatgc aactgttggt gaagatggcc
     4441 cgatgatcaa gtcataatct gcaaagactt tttcaaaatc tcgtttgatc aatgtacgga
     4501 cttgtcccgc ttttttgaag taagcgtcat aataaccagc acttaaggag aatgtaccta
     4561 acatgatacg gcgttttact tcttcaccga atccttctga acgtgagttg acatatacat
     4621 catctaatga tttcacattt tctgagcgat aaccgtagcg gataccatcg aatcgttgca
     4681 agttggaact tgcttctgat gaggcaatga tataataaac agccacaccg tattttgaat
     4741 gaggcaagct gacttcttcc acaacagcac ctaatgaacg gaatgtttct gctgctttca
     4801 atacagcttc ttttacgcca ggggccacac cttcgcctaa gtattcttta ggtaaagcaa
     4861 tcttcattcc tttgatgtcg cctgtcagtc cctctgcaaa atcaggaact gaaacgcctg
     4921 aagaagtacc gtctttttcg tcataaccgc tgatagctgt caatgctaat gcattatctt
     4981 tcaccgtacg ggtcattggt ccgatttggt caagagatga agcaaaggca atcaaaccaa
     5041 aacgtgagac acggccataa gtaggtttca tccctacgat gccgttaaaa gctgctggtt
     5101 ggcggatact tcccccagta tcactaccta aagaaactgg aatttgtcca gctgcaactg
     5161 ctgctgcaga accaccagaa gagccaccag gtacttttgt tgggtcccaa gcattttttg
     5221 ttttcttgaa ataagaagtt tctgtacttc cacccatagc aaattcatcc atgtttagct
     5281 taccaacagg gatcatatct gcttgataga ttttatccat gaccgttgca tcataaattg
     5341 gttcaaaatt gtaaaggatc ttagatgcag cggttgtcaa gatatctttt gttacgatat
     5401 tatccttgat accaattgga ataccagcaa ggacgttgct ttcatcaatc cctttttcat
     5461 ctaaagcttt tgcctgttcc aatgcttttt cttcgttcaa tgtaatgaat gcttcgacct
     5521 caggctctgt ttctttgatt cgttcaaatg ttgcttttgt caaatcttgt acagtgattt
     5581 ctttcgatac aagcatatga tgcagttctt ctagagaacg attgtgtaat tctgtcatta
     5641 tgcgccagcc tccccattat cgatgattgc gggtactttg ataaagccgt cttctgtttc
     5701 cggcacattt ttcaataatt catcgcggtt ccatccagct tgcgcccgat cttgtcgcat
     5761 cacgtttact gtttcaacca cattcgacgt aaatggaaca ccttctgtat ctacttcttc
     5821 cagcatttca accatatcga tgattttacc taattggtcg gtaaaacttg caagttcttc
     5881 atctgcgaac gcaagttttg ctaatttggc aacgtgtttc acttgttctt cactaatcgc
     5941 catactaccc cttctttcta aacgagttaa aaactttgct ctctatttta acacaagagt
     6001 gccgtgtctg aaattgttta ttgaaatttg tctgaaaaaa ctcatttttc attcttctac
     6061 tgagcgactt ttagccaatg catctgccat ttgatcttct gtccaaactt cgattcctaa
     6121 ttcttgtgct ttggtcagct tgctgccagc atcttctcct gctaccacga tatccgtttt
     6181 tttcgatacg ctaccagtca ctttcccgcc aagattttcg atcgtctctt ttgcttcttc
     6241 acgagtaaat cgtgttagtt taccagtaag gactactgtt ttttctttaa aaggagactc
     6301 gacttcttgc aattgggcat ttcgaagccc tttgtattcg aaattgacgc ctgcttgttt
     6361 taattcattc atcaattcat ggacttcttc gttactgaaa taagtgacta cactgtcggc
     6421 aatgatatca ccgatcgtat caagcgcaat aatcgactca tagtcacttt tactcaatgt
     6481 ttctagatca ccgaaatgtt ctgctaaaat ttttgctgct ttcgctccga catgtcggat
     6541 tcctaacccg aaaatcaacc gctcgaccga attatctttg ctgttgtcga ttgctgtcaa
     6601 aatattattt gctgattttt cttttatttt gtccaacgtc aataactctt cttctgtcaa
     6661 tttgtaaaga tcagcaacat ctgctactag ttttttatca tacatctgtt ctagtacgcg
     6721 cggccccaac ccatcgatat tcatcgcatt tcttgaaaca aagtggttca aaccttcttt
     6781 catttgagca gggcatttag gattgatgca ccgtaaggct acttcttcat ccaaatggac
     6841 aagttcactt ccacaaactg gacaatgtgt aggcaattgg tattcttcgc tgtctttagg
     6901 tcgtttatct aacacgactt gcgaaacttc tgggatgatg tctcccgctt tataaatcag
     6961 aactgtatct ttcaagcgga tatccttcaa cttaatataa tcaccgttat gcaggctggc
     7021 acggcttact gtcgttcctg ctactcggac tggtgtcatg atagctgttg gcgttactac
     7081 ccctgttcga ccgactgtcc attcgatgtt ttcgattagc gtttcaactt cttctggcgg
     7141 aaacttgtaa gctgctgccc atctcggtgc tttgacagta aaaccaagtt gatcttgtag
     7201 cgagaattca ttcactttga tgacgattcc atcgatttca tagggcaaat ccacacgttt
     7261 gtcatgatat tcttcaatgt atgaccacac ttcatcaatc gaatgacata gacgtttttc
     7321 ccgattcgtg tggaatccaa ttttttctag ctcttctagc gcatcatact gggtttttgc
     7381 ttgcatagga ccgaaatcag ctactgtgta taaaaaagtg tccagatttc ttttcgctgt
     7441 gattttagaa tctaactgac gcaaagaacc agctgcggcg ttccgaggat tcgcaaagat
     7501 atcttttccc tctgcttctc tgtcttggtt caattggaca aatgaccgtt ttggcatgaa
     7561 acattcgcct cttacttcga tgttcattgg ttcttttaat ttgattggga ccgaccggac
     7621 agtttttagg ttttcagtga tgttttctcc tacagttcca tccccgcgag tcgcacctct
     7681 cacgaaattt ccatcttcat aacgcaaaga aacggaaagt ccatctattt ttagttcaca
     7741 gcaatagtca actacacgtc ccactgcttt ttgtacacgt tgatcaaaag ctatcagctc
     7801 ttctttgctg aaaacgtcgt tcaaactgta aagcggaata tcatgagtga ctttttcaaa
     7861 accttctaat acttttccgc ctactcgttg agtgggagaa tcagacgtga tcaaatcagg
     7921 atattgttcc tcaattgcta ctaattctgc gtattcttta tcataaacat agtcttccac
     7981 tgttggttta tcttctacgt agtattcgcg agaccattgg ttcagtcttg tacgaagttc
     8041 ttctgctcgt ttagcagctt cgtcaatcgt catttcatgt tccatcattt accctccact
     8101 actaagcttt ttcaattggc gcaaaggcag ccaaaagacg ttttactcct tgacttggga
     8161 aagccacatc tagttctaga tccttcgacg tcccgcttac tcggacgact gttcctagac
     8221 cccatttttt gtgtttgact ttatctccag gtttccagct gttattttcc cctccagtag
     8281 cacttttaga gggaacaacc gctgtctctg gctgtttata gctatatgct gtttttttag
     8341 cgaatacagg tgttttttta ggcgtaggac gcatgccttc gatttccagt aactcctgat
     8401 cgatttcttc tacaaaacga gaaggtcggt tatattgcgt ccgtccatat aatgttctgg
     8461 agaaagcatt tgttaaatac aacgcttctt ctgctcgcgt gatccccaca tatgcgagac
     8521 ggcgttcttc ttccagttcg ctttcttcca tcaatgctcg agataaagga aaaaccccct
     8581 cttctagacc aatcaggaat acaactggga attctaatcc tttggctgca tgcaaagtca
     8641 tcaatgtcac ttgggaagca tcttcttcta aattgtcaat atcggaaaca agtgccagat
     8701 catttaagaa gaccgttagt ttttcttctg gtgcatcagc gtcttcttca ttttgctgtt
     8761 cgaattgttt gtcgaattct tgtgtgaccg ttaaaaattc ctccaagttt tcgatgcgtg
     8821 cttgtgcttc taatgtattt tggattttta agtcttctag atatccgcta cgatccaaaa
     8881 cctctttcgt caattctgtc actgtcaagt atgggatcat ctgagtgact tcttggatca
     8941 tctctccaaa tgcacctaat tgctgtcctg cttttccacc gatatttgcc agatccacat
     9001 tttgcgctgc ttcaagcagt ggccattcat gaagagaagc aaaactgcgt agtttttcga
     9061 tagatcctgg tccgatgcct cgtttgggcg aattaacgat acgctcaaaa ctgattgaat
     9121 cttgaggatt tgccagcaca ttcaaatacg ctaaaatatc tttgatttct ttacgatcgt
     9181 agaacttgtg ccctccaacc attttataag gaatatttgc tttcaacaga gtttcttcca
     9241 ttacacgaga ttgtgcgttc gtccggtaca agatggcaaa gtcgccgtaa ttccgatgat
     9301 tgcttcgaat ctcttcttgc atccgatcta cgataaaacg ggtttcgtct cgttcattat
     9361 ctgcacggta gtaagtgatc ttgtttcctt ctttgttttc tgtccacaag ttttttggtt
     9421 ttcgattgct attgttttca atgacttggt ttgctgcgct aaggatgttt ttcgtggagc
     9481 gatagttttg ttctagcaaa attactgcag catctggata atctttttca aaatccaaga
     9541 tgttctgcat atctgcaccg cgccagccgt aaatactttg atctgcatct cccacgacgc
     9601 acaggttcct aaatctacct gccaataaat tgactagcgt atactgtgcg tgatttgtat
     9661 cttggtactc atctacatga atataatgga atttgttttg ataatatgtg agtgaatcag
     9721 gatgttcttc aaataatcga atcgtattca tgatcaggtc gtcaaagtcc atacattgat
     9781 tatattgaag ctctttttgg taagcagcat aacattttgc cgcaatctct tcgtaataac
     9841 tgccttgcat ttttgcaaaa tcctgagggg tctgcaggct gttttttgct tgagagattg
     9901 ttcctaatat acttcgagga tcatattttt tcggatcaat gttcagttct tttagtatcc
     9961 gtttcatcaa ggtcagctgt tcagaagaat cgatgattgt aaagttccgg ttatacccga
    10021 taaaatcaac atctcttctt aaaatacgca cacacatcga gtgaaaagtc gatacccaga
    10081 catcttcgcc tccagatgcg agaatcgcat tgacacgttc tttcatttct tttgcagcct
    10141 tattggtaaa agtaatcgct aggatgttcc aaggattgac ttctttttcc tcaatcaaat
    10201 aggcaatgcg gtgtgtcagc actctcgtct ttccacttcc tgcacctgcc attagcagta
    10261 atggtccgtc agtgtgaaga acagcttctt tctgacgggg gttcatcccg tttaataatt
    10321 cagctttgga tgacattaac aacatccttt cttttatcaa tcttgttaat tatagcattt
    10381 tcttggcttt cattaaacta gctagttcaa aatcatttgt ttctttttat ggatttttcc
    10441 ttgtcaattc gttgatttcg cgctaaatta aaagaaagcg aggcgtttga atggaaaaaa
    10501 aaggaaaaat caagaaatta gataagactc agatatattt tattctaaaa ggaatatttg
    10561 ttggactgct gacaggaatc gtcgttagcc tgtttcgatt atctatcgaa aagctaagcg
    10621 atttagttcg aagtatctat gaaatgagtc gggaacagcc gatttactta attggcctag
    10681 ctatttgctg catccttgca gcatttttcg tgggttatct ggtcaaaaat gaaccggata
    10741 tcaagggaag cgggattcca caagtagagg gacagcttcg cggggaatta tcaatgaact
    10801 ggttctctgt tttatggaaa aagttcattg gcggtgtact ttcagttggt gcgggccttt
    10861 ttctaggtag agaaggacct tctatacagc ttggcgcatc cattggacaa ggagctggac
    10921 aattgtttcg gagtccatct tcagaagaaa agattttaat ttctagcggt gcaagtagcg
    10981 gacttgcagc agcattcaat gctcctatcg caggattact ctttgtttta gaagaaatcc
    11041 atcactcctt ttctccactt gtttggctga catcatttgc ttcagcaatc actgctaact
    11101 tcgtctctct ttactttttc ggcttgagac ctgttttata tctaggtgac cttccttctt
    11161 tgccgttgaa atattatggt tccttagtga tcttaggagt acttctaggc atcttaggtt
    11221 ttatttatca gaaggtcttg ctggctttgc caaaatttta caaccgattg cctttaccag
    11281 cttattttca cgggttcgtt cctttcttgc tgattttgcc aattggttat ttatggccta
    11341 gtactctagg cggaggcaat caaatcgttt tagcttttgg acatgcttcc ttgccaatca
    11401 ttatgattat cggtttgttt gttcttcgat tcgttttttc catgatttct tacggtggtg
    11461 gtcttccagg ggggattttc cttccgatat tgacattggg ggctttaatc ggtagctttt
    11521 atggaaacat tatggttgat ttcgggatgg atccaatcta catcaaggat tttgtcgtta
    11581 ttgccatggc tggttatttc acagcgattg gaaaagcacc gctgacagca attattttag
    11641 tgacagaaat ggttggctct cttaatcatc tgatgccttt aggattggct gctcttgttg
    11701 cttatatcgt caatgacctt ctcggcggta atccaattta cgaatcatta ttggaacgtc
    11761 tacttggaaa tactcagacc gcctcactaa aaggtgcaag gacaactttt gattttccag
    11821 taacggcaga gagttcttta gacggattaa tggtacgaga cttcaattgg cctaaaaata
    11881 tgctgctaat ctctatacgc agaggaaatc aggaaatctt gactcacggt gatacgatca
    11941 tgaatgtagg agatattttg gttatcttga ctgatgaagc aaacttgcca agaatcaagc
    12001 aggaaatcga ggctaaatct tctatcacaa atttgaagca atcattttaa cgaacatgga
    12061 aaaactattt tacaacaact attcatctac actacttgat tctatatgat tctataaaaa
    12121 aagaagagac tgggaaaaac cagcctcttc ttttttattt ctatgcttct gctgctgcag
    12181 gagcttttct caataaacca taaatcacac cagatacgac tgctccgata gcaataaaca
    12241 ccaaatacat gaccgggtga ctcagtaaga atacaacgaa aatcccgcca tgaggagcca
    12301 gtaatttgat cccgaaagct ccgactaatc cgccagttaa agcagaacca ataataaaac
    12361 ttggaatggc acgaatcggg tcagctgctg caaatggaat cgatccttcc gtgacaaacg
    12421 atagtcccat cacgatgttc gtcaaaccag catcttgatc tgttttgctg aatttattct
    12481 taaacaaacg tgtagcaacg aaaattgcca atggaggtac cattcctcca gccataacag
    12541 aagccatcac gacacttccg ccagttgcaa cagtcgtagc taaagttgct gtaccaaaca
    12601 cataagcggc tttgttgatt ggaccgccta aatctgccgc catcattcca gctaataatg
    12661 caccaagtaa agcagcattc gaaccactca tacttgtcaa gaaaccgttc aatgcatcat
    12721 tgattgcttt catagggaca ttgaccagca acatcaagaa accagtaatc agtaagccaa
    12781 acactggata aaagaggatc gttttaattc catccaatga ttttggtaag ttcttgaata
    12841 atttacgtaa aaatacgatg acataaccag ctaagaatcc accaatcagt gcacctaaga
    12901 atcctgcacc gcctgtatta gctaatgcac cagcagcaaa tccaacgatc aaaccagggc
    12961 ggtcaccgat acttgaagca ataaatcctg ctaataccgg cagcatgaaa ccaaatgcag
    13021 cttgtccgat ttggttgaac cagctagcag cttgattgta attccctaga tttgataatt
    13081 gatcatgtgg cacgccaata aattggtcga tcatgaaaga aagcgcaata gcgattcctc
    13141 caccaataac gaaaggtaac atgtgtgata cgccgttcat caaatctttg taaattcttt
    13201 gtccgatagt accatccgca tttccttctt ctgaactgct ttcttttcca tcaccatgga
    13261 atactggtgc agtaccacta agggctagat tgatcagctc ttctggttta cggataccat
    13321 cactgacagg acgattgatc agttcttttc cgtcaaagcg attcatctct acttttttgt
    13381 ctgctgcaac gattacacct tctgcacggg cgatgtcttc agcagtcaat cggtttttga
    13441 ttccttctga accgttcgtt tcgactttga tctccacacc catttctttc gcttttttct
    13501 tcagagcatc ttctgccatg taagtgtgag cgatccctgt tggacaagct gtaacggcaa
    13561 caacgaattt tctttctgga tgagcagaag cttctgcagc ttgtgtttct tgttctgctt
    13621 tttcttctgc ttctttttgc tcttcagctg tttggaacaa gtcttggact tcttctggtg
    13681 tatttgcttc ttttaatttt cctacgaaat ctgcatcaat cagcaatcga gatagtgctg
    13741 ctaatgcttg caaatgtgtg tcgtttgcgc cttctggagc tgcgatcatg aaaaacagat
    13801 aagttggctg tccgtctaag gcttcataat ctactccttt ttggcttttt gcgaataaaa
    13861 ctgttgcttc tttaactgca ctgtttttcg cgtgaggcat ggcgattcca tcaccaagac
    13921 ctgtagaagt ttgtgcttcg cgggctagaa ttccttcttt atatgtttcg atatcggaaa
    13981 tccggccggc atcaaacatt ttttggacca tttcatcgat tgcgcctttt ttatcagtcg
    14041 cttgcaaatc catgatcatc gcttctttga ccattaaatc cttgatattc atgattatcc
    14101 tccttgaaac taatcaattt ttgtgatttc aacttctggc agcaactcat caatcaattc
    14161 gcgagctgcc aagtcatcag aaaaagctgt tgcgcttccg caagcaactc cccatttaaa
    14221 ggcttcgatt ggatctttcg tacggctgta agccccaata aagccggcaa tcattgaatc
    14281 ccctgcacct actgaatttt tcaatgggcg aactaataca ttcgttttat aagttccttg
    14341 ttccgtgaag agcaaagcac cgtctccagc cattgagatc agcacattct gtgccccttc
    14401 agctagcaat tttttaccat acggaatgat ttcttctaca gattggaagg ttgtattgta
    14461 aagctcagct aattcgtgat tgtttggttt gatcaacaat ggtttcttaa caagtgcatt
    14521 ttttaggtca tcacctgttg tatcaatcac gaaatctgca cctttttctc gaatgatatc
    14581 aatcagttct tgataaaatc cttttcgcag gctagccggc gcgcttcctg acaatacgac
    14641 gatatctcct tgtcctactg ttcctaatgc ttgcttcaac tcatcgattt cttcatctga
    14701 aatagatggg cccaaaccgt taatttcagt ttcagtatct gattttagtt tgatattgat
    14761 tcttgtatct tcttttacgg ttgtgaacaa agactggatt tgttcttttt caagccactt
    14821 cgaaataaat tcgccagtga accctcctaa aaaccctagt gctgtagatt gagaatcgat
    14881 ccgtttcaaa atacgggaaa cattgatccc ttttcctcca ggtaacttga agtcttcctt
    14941 cattcggttc aaatcgccta gttttaaccc atctacgcgt acgatataat caattgatgg
    15001 attaagtgtt actgtgtaaa tcattgtatt gcctccttaa ttgttgtctt ttcacggaat
    15061 tcattaacga attctaatgg acaacgctcg gttatgatcg tggctgcttc caaaggtgca
    15121 acagaggtga aggacaactg gttgaatttg gtatgatcaa tcaatacaaa tgtctcttcg
    15181 gaatttttca tggctaaacg tttaacagct gcctcttctg ggtccggagt cgtgaatcct
    15241 tgttcaagat gggcaccgtt cattcccata aatgctttat taaaatgaaa attttttagt
    15301 tgttctatcg cattagatcc taaaacagca ttagttgcca gctttatcgt tccacctaaa
    15361 ataatggtag caagctccaa atcaactaaa tttgccgcat gttgaacgga atttgtcact
    15421 actgtgatct gttttccttg cagaaaagga atcatttcta acgtagtaga gccagcgtct
    15481 aaataaatga catcttcgtc attaatggtt tcagctgccg atttggcgat ttgctgtttt
    15541 tcgtgaacgt ttttgagtga tttttcactc atattctgct caaaattcaa taattgctct
    15601 ttcttagctc cgccatgaac tctttctaga aacccactat tctccagctc ttgtaaatca
    15661 cgtcttatcg ttgattcaga agcattaaaa aggtttacaa gatcttgtga tttcacgatt
    15721 ttctgctgtt caagcaagtc taggattttt tgtctacgtt cctctgtaag cattttcacg
    15781 atcacctcaa tacaaataat agcatatttt ttttctactc gcaatataaa tcagtcaaaa
    15841 acgttcataa aaattataaa tcagtcaaaa aaaaataaaa aaccagtcaa aaagactggt
    15901 tttttatttt tttgtctatc atcaagccgt tttatcgttt tttattttcg cttcttgttt
    15961 ttttcatata aacagaagca ggttttcttt ccttatgaag aagataataa taaagtccca
    16021 tcccgccaaa catgaccaaa aaaccgatga ctgatcgaat aggaaaatta ggaacaaaaa
    16081 agagacagac ggataataat gatgccggaa ccattattcg ataatagagt tgtttatcca
    16141 ttttcttcac ctcatatttt ttgtaaagta atcaattgtt ctaattctcg gtaatctaaa
    16201 aattgcacac gcagatgctg ctcacctttc ttgacatcga attggatact tcgccgcttt
    16261 ttctttattc gtttgaaggt aacatcagag agtctatgtt tgatttcctt taacggtaat
    16321 tctgacaggg attctgaagg aacatagatt cttaaggata aaagatactc ttgatatttt
    16381 tcatctgtta cctctacttc tagatattcc ctaatataat aacaataagc ttcgattcca
    16441 ttatccaaag caacagtcgg atcgataact ttatagcaca tcatgcgcga gcgattctcg
    16501 tcaacccaag gaaaatacgc ctgagcattt agtgttccgc gaacacgcct ttctttataa
    16561 tctccttgtt gaatatcata actttttgtt acaaaaaatg aagcattctt tttaggaaca
    16621 ggttgcattt gtgcattctg atactggaca gattggatcg tatggtcagt gtaaatgtat
    16681 tcaacgaatg gcggtttcaa taaaccgaca ccattgtccc aagcaagatg atcaaaccca
    16741 agctggtccc taaaatagga ttgaaacatt tgattgtttg gcttttgcca gttaaagggg
    16801 tctcgataaa gctggataca tatgacttcg ttttctaatt ccttcacttt ttctacttgt
    16861 tggatgtcga gaaaaatcgg tttagggatg atttgatgat aatagcgact ataatacatt
    16921 tcccaacacg aagtgaaaca taaaccttgg taaaaaagat cgtatcctgg aaattggttg
    16981 caatcgacta ctacttcccc gttttgttgt ttcattttag gtaaatgttc gatttcatcc
    17041 tttttctcaa acaatagccg ttgagagatc tgttttgtat tgtgatagat aaactcgcta
    17101 taagctcgca tataggcgaa caccccatga gcaatcattt ttttctgaat gaagtctcga
    17161 atcaaaaatt gcttttcttt gaaaacagag atagacaata cattttttat caataattga
    17221 ttatcttcca agcgaaaact acattcgttc tcgtcatttc ctacaactaa ccaactttcg
    17281 tctcttaccg atgctagcat tattttttct tgaagctttc gaagatcata cggatccgct
    17341 tgttgtgtga aagagcggat aaatgttggc tggatcaaca gacgtgtcaa aatagcccaa
    17401 tcgcttattt cctgtttttt ttcttcttca tttaagtctg tgagctggat agtcatcaat
    17461 aatttatctt cgccaatcat tttctcacct ctttaaaatc tttttataat ttaattataa
    17521 ccaacgataa agaaaaacta aaactttatg tcttagaaac caatttggac gattacatga
    17581 tagactaagt aaaaagaaac aaagaggtgt ttacaatggg gttgaaattt gaacgtacag
    17641 ataatttaga taaacttttc gaatcatttg ctgtcgatcc ggaaaaaaca gttgcaccaa
    17701 aagaagagat cgatcgattt ctaaaaccac agccacaaaa tgaaaagaaa aaagacaaga
    17761 aacaaaagta agttaagctc aaaaaaagac ttaccagcca aacttttatg aaagagtttg
    17821 actggtaagt cttttttatt ctttttatga ttcaattgct tgttcgattg ctgcccacgc
    17881 ttcttctttt ccctgttttg taacggaaga aaagagaata aacgtgtcat tgcgatcaaa
    17941 atccaacgct tttttgattt cgctctcatg cttgttccat ttaccacgag ggatcttatc
    18001 tgccttagtg gcaacaacaa ttacagggat atcataatac ttcaaaaatt gatacatctg
    18061 gatatcttct tgagaaggct tatgacgcaa atctactaaa gaaacgaccg cacgtagctg
    18121 gtctctagtc gttaaatatg tctcgatcat ctttccccat tttgctcgct cagttttgga
    18181 tacttttgca tacccatatc ccggaacatc gacaaaatgt aatgcgttct cgatcaaata
    18241 aaaattcaat gtctgggtct ttcctggctt accggaagta cgggctaaat tctttcgatc
    18301 aatcaatgtg ttgataaaag aagatttccc tacatttgat cgtcctgcca gagctatttc
    18361 tggcaattgt gtatctggat attgttttgg tgccactgca cttatgataa tttcagcttg
    18421 atggactttc atggtctctc tccttaacaa ggtgatgaat aaagcaagcg gctgtcgcaa
    18481 aagccaaaat gacttttacg gcagcctctt ttcatcaacc cgcttttttc tctgaatctt
    18541 tatagattac tgttggctca ccagacaatt cagctgcttc ttttgtgata atcacttttt
    18601 cgatgttttc atttgaaggg atatcaaaca tcacatccat catgatttct tcaatgatgg
    18661 aacgaagtcc tcgagcaccg gtattgcgtt cgattgcttt tttcgcaatg gctctcaacg
    18721 cttcaggttc gaattcaagt tcggtattat ctagagaaag aagtttttga tattgtttga
    18781 ctagcgcatt tttcggctca gtcaagatcc gtaccagatc atctgttgtc aatttctcta
    18841 aagctgccat aacaggtaat cgtccgataa actcagggat caatccgaat tttagtaaat
    18901 cttcaggaat gatatgctgc atgacacttt cgtcttcaga aagtttttgg ttttgtgtac
    18961 caaatccaat cgtcttttcg cccatacgat tcttcacaat cgtttcgatg ccatcaaatg
    19021 caccacctac gatgaacaat atgttcgtcg tatcaatctg aataaattct tgatgtggat
    19081 gtttacgtcc tccctgaggt ggcacgcttg caacagttcc ttctagaatt ttcagcaagg
    19141 cttgttggac accttcgccg gaaacgtcac gagtaataga tacattttcg cttttacgcg
    19201 caattttatc gatctcatca atatagatga tccctttttc tgcacgttcc acattgtaat
    19261 cagcagattg aagcaattta agcaaaatgt tttctacatc ttcccccaca taaccagctt
    19321 ctgtcaaact tgtcgcatct gcgattgcaa aaggtacatt caatgttttt gctaatgttt
    19381 gtgctaaaaa tgttttacca gaccctgtag gtccgatcaa gcagatattg cttttttgca
    19441 gttcaacatc atctgtgttt tcttgtgctt gctgattgac acgtttatag tgattgtata
    19501 cggcaacagc taacgagcgt tttgcgcgat cttgtccaat cacgtagtta ttcaatactt
    19561 caagaatttc tagtggttta gggacttcag tgaattcgcg tacagcttct tcataaaatt
    19621 cttcatcaat gatttcttta cataggtcga tacattcatt acagatgtag acccctggac
    19681 cagctacgat ctttttcact tcttcttggg ttttcccgca aaaagaacag cgtacggtct
    19741 cattgctact tggattgtca tacatggtct tcacccctta acttgcaaaa agtatgcaag
    19801 aaactatcaa agactttaca gtcttttact atcataacat agtttagtaa aaagaaaaag
    19861 tgtttaacaa aggatcaact gacctatacc tttgcatttt ttactcttaa caaaaaataa
    19921 ggaactgtga caaaatcgtg tcacagtccc ttatttcgaa taaacaattt tctagaagta
    19981 gcttcttcag aaatgattta ttacttgatt tctattcttt cgcttctgtc gctgtacctg
    20041 tgatcaattc gattgctttt ttcattgtca catcatgttc cagcatatct tctgtcaaca
    20101 cgcgtttgat ttgttcgatt ggcatgttgt atgtttctga taattcttgg atttctgcat
    20161 tgatttcttc ttctgttgct tgaagatttt cagcagctgc aattgcttcg atcacaagat
    20221 ttgttcttgt gcgcatttct gcttcacctt cgaattgttt atgcaagtct tcttctgtag
    20281 aaccagttaa ttgatagtac atttcaggag agataccttg acgttgcatg ttgttcaaga
    20341 attcgtccat tgaacgatgt acttcatcat gaaccatcac gtgtggcaat tcaacgattt
    20401 ctgcgttttc aacagccata cggatcgctg cttcatcttt tgcatcgtcc gctgcttttt
    20461 cttttgtttc tactaattct ttgcgatatt tttctttcaa ttcgtctaat gttgatactt
    20521 cgtcatcaac atcttttgcg aattcgtcat ctaattcagg cacttctttt gcttttactt
    20581 catggattgt cactttgaag actgcttctt ttccagcaag atcttctgct tgataatctt
    20641 ctgggaaagt tacatttaca tctagacttt cacctgattt atgaccaact aattgatctt
    20701 caaaacctgg aatgaatgag cctgaaccta attcaagtga gtaattttcg ccttttccgc
    20761 catcaaacgc ttcgccatct acaaagcctt cgaagtcgat tactactgta tcgccatttt
    20821 cagctgcagc atcttctttg ataactaatt cagcttgtgc ttcttgttca cgtttgatac
    20881 gtgcatccac gtcagcatct gttacttcac ggtcttgttt ttcaacaact agatctttat
    20941 attgtcctaa ttttacttct ggtttcactg ttacttcagc agtgattacc cagtcttgac
    21001 ctttttccat gctttcaaca tcgatttttg gttgagaaac aggatcgatg ccagcttctt
    21061 tgacagcagc ttcataagct tctggtaata cagcattcaa tgcatcttca tataaagctt
    21121 cttcaccgta catacggttg aatacttgac gagaaacttt ccctttacgg aatccaggta
    21181 cgttcaagct ttttttcact ttattaaacg cagttgttaa tcctttttgg atttcgtctt
    21241 gcgcaatcgt aaattttaaa acaccatcat tcgtgccttt tttttcaaat gttgcagtca
    21301 tttaattccc tccgagttta gaaattcatt ttatacatca aaaacgtttc atgcatacct
    21361 ttaaatagta cactaaccct ttcaaattgt aaacatattg aatggataga atccttgttt
    21421 ttcataacat ttttatcttt ttcactgata aaatctaatg gaagaagatc atttgctgca
    21481 aaattttttc tctttttttt aaaaaatctt gtttttcatc ttctgtacct tcatacatcg
    21541 tttttcctgt acacgcctct acagtcagtt gaaaccagcg cttcgggtct tcgatgtatg
    21601 tatcatagac aggataaaca attgcagatt gcaacgtgaa ttcttcattt aacacggaac
    21661 taagcagcgc atcttcatta ccgtaacgat ctgaaaatac acataattgc tggtaacttg
    21721 cctgctgctg cggctttggc agatcttttg gtatgacttt gactaacttt tcttcaatcg
    21781 tcaaatagaa aacaggatgg cattcgttca attgcctaag tgtctccagt aattttgccc
    21841 ttgctaaaat atggacctct ggcgatacaa taagtttact cgctgtttgg ataaactcat
    21901 gataaggaag ctgttcgatc tcatcaatag acgcaagctg acgtgcaggt tccaacgaag
    21961 gaagttcctc cgatttattg tggagtgcct tgatcttctg cctctccatt tgtccggata
    22021 attcttctgc aaattggatt ttttcaatga cccgctgctc gaaagcttca taaaaatctg
    22081 tacttgctat caattttcta gcatataaaa aatcttgtgt actgattaac aagtcaaaat
    22141 aaaattcagc aaactcctca ttttgaagat actgtttttc atgcaagagt gcttgcttca
    22201 atgcttcttt tttctcgtcc aactcgtaaa gacaaaaaac aagcaggcta ttagcctcaa
    22261 agctttcttt caactcgtaa gctcgttgaa ataattcttt tgcctgctga tattgctggt
    22321 ttgctagtgc ttgttgtgct actcgcatta aattctcata tttttctgga aaatcaatcg
    22381 gcttcacgca gtgtcctcct cttgctcatg ttcagctcat gttcaatagt agcaaaacaa
    22441 aaaaagcatg acaattaaaa ataactgaag caccctctaa aagctagatt ttagatctga
    22501 cttttagaag gtgctttcaa ctgttactgc tttttattgc tcatcagctg ttgacttcct
    22561 ggttgaatgc tttgatcaga ttgatcgtaa caacacttgt attagtgaaa aaatcgccta
    22621 gatgttgctt tttctgatta aagattgctg gaagataccc taacatcagc aaaggaaatt
    22681 ttagaatgaa ccggcaagca ccttctctaa ctaaaacggt tgaccagcta agttcttctt
    22741 catcaaagct gatgactcga ataccaaaga tcattttccc aatcgtttga ccatgattga
    22801 atttcgtcaa taaaataaaa tacgctagat aaataagtaa ggctgtgaat ccgtagatac
    22861 tcagataaga atctgaaaaa ttaagccaac ctagattttt ggcaatacca agtgttaaac
    22921 gcgtaatagc tccgatacac aaaagatcga ccaagaaagc aaacattcgg ataaaaaaac
    22981 ctgcatagaa atacttagga aaatcatttg cttttggcgg ttcatttctt gtgtccgtat
    23041 actttttcca tttacgttgt ttctttttga tttcttcggg cgtcaaaggc tctctttcaa
    23101 aagagctcag taccttttgg gaaaagttgg agtcaggtcc tacagcaggc tgctgttgct
    23161 tatctttttc ttgttcctta ttttcatttg aaagctctga catgcttact cacctccgta
    23221 ataatacatt gcttttggtg attccgctgt ccctagattc tcaagaacgg ataagatctg
    23281 actagtctca gaaggcttca atccctggaa ttctgctagt ttacttccta accatgtact
    23341 agcaaaccca gatggcgtgg aagaatattc tactagttcc gcatcttcaa gctgttgttc
    23401 ctttcgcata gcttttaaag catcttcagg aaatcccaat tcatcgacta aacctacttc
    23461 ttttgcttgg acaccatcat aaatccttcc atcagcaatt tttttgactt cttcttcaga
    23521 tttattccgt ccctcgctga cgattgctac aaaacgacta tatgcgctgt cgatatatgc
    23581 ttgaagcacc gcttcttctt cttttgtctc tggtcgcgtt cctgaaccca tatctttcaa
    23641 cgctccgctt ttaactgttg tatcttccac acccagtttt tctagaagtc ctgaataatt
    23701 caatcctgac atgatcacac caattgagcc ggtcactgtt tcttctgttg caaagatttt
    23761 atctgcttga gcagaaatat agtagccacc gctagctgcc atgtttttca tgctgacata
    23821 cattgggata tcatgttctt tacgaatcgt atccaatttc ttagcgattt ccgcactttc
    23881 gtagacaccg ccaccaggag aatttacttc taaaaagata cctttgactg ttggatcttc
    23941 ttcaatcgcc ttcagttgtt ccataaaatt tttatgattg taaccttcag aagcaaataa
    24001 acctgaagcc cctcccgcag caatcgttcc atctactgat aattttacga ttttttgcgt
    24061 actgtctccc tcttccaaca catttgaagc tagttcttca tccccatata accaactgtt
    24121 caatccctca atttgatcgt tttcctgagg cttagtcaaa ctagctgaaa ctaacgaaac
    24181 cacaaataat cctgcagcaa tcagaactgc tgcccaacgt ctcttattca ttctttctcc
    24241 tttctaatac aagtttttta tgacgatcac agtttctgac tgctcagaag tgtcgaaccg
    24301 ctctgctttt tcttcccgcg catacccgga aaacgactct tttgtcaatt catcttctac
    24361 cgtaaactca cgagcttcag caacttccaa ggcatcaggt gcgatttctt ggatgctatc
    24421 ccagccagta tctaaaaata ttttcgtatc atctgataca ccagctgatg cttcgaattt
    24481 ggacaattgt ttttttaaca ttcccagtgt catgatctca atttttgaat ccatttttac
    24541 tcctcctcta tccgattact ttctattgta ccgaactcct gaaaaagatg atagataaaa
    24601 acccattatt ttttgacata aaaagagcat ttgacaaagc atttgatata taccaattta
    24661 ttttttattc tttttttgtt gacaagaaca ttcgcaaaag gttatgattt taaatgtttc
    24721 cagataaaaa acaaaagagg aggatagtta taccttttag gatagcgcca ggtctgtgta
    24781 aacagatgac gaggagaggg tttatcgaaa gattcggcgg atggccctag ggactgcact
    24841 ctacagaaaa tccacaaaaa atatctgcaa agataaaaca aaaggatttt cctgcagctg
    24901 gaagcattca tacgaattca ttatagaaag taggatgttt tttatgtgcg gaattgttgg
    24961 aatgattgga ttaaaaaatg taacaccagg attgattgac ggtctagaaa aattagaata
    25021 ccgtggttat gattcagctg gtatctttgt ctcagatggc acaactgatt atctggtcaa
    25081 agcacaaggc agaattcaaa atttgaaaaa caaaataaat attgatacta caggaaatat
    25141 aggtattggt catacacgct gggcaactca cgggcaacct tctgaagaaa acgcccatcc
    25201 acatacttcc caaagtggac gcttcgtgct cgttcacaat ggcgtaatcg aaaactttga
    25261 agaacttaaa attgcttatt tagcaaatga ccactttatt ggtgagaccg atactgagat
    25321 tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca acgcaagagg cgtttttaaa
    25381 agctttgcgg gtcatcaaag gttcttacgc tttcgctttg attgatcgga cagcacctga
    25441 tgttatttac gtcgctaaaa ataaaagtcc actattaatc ggactcggcg atggattcaa
    25501 tgtgattgcc agcgatgcaa tggctatgct tgctcatacg aaggaattcg ttgagattga
    25561 agatgaagag atggttaccg tcacatcaga aaaagttatt attcaaaatt ttgcaggtga
    25621 catcgtagaa cgttcttcat tcgaagcaca agtagattct tcagatatcg agaaaggtac
    25681 ctatcctttt tatatgctga aagaaatcga cgaacagcct attatcatgc gtcgtatcgc
    25741 tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat caaaagctgg tcgatacatt
    25801 gtctgatagc gatcgaatct atatcgttgc ttgcggaact agttaccatg cggggttagc
    25861 aggtaaacag actctggaaa aattgacaca gatccctgtt gaggttcatt tagccagtga
    25921 atttggctat aacacacctc ttctttcaaa aaaaccattc tttattttct tgagtcaaag
    25981 tggcgaaaca gcagatagcc gccaagttct ggtaaaaatc aaccgtctcg gctacccttc
    26041 acttacgatt acaaatgttg ctggttctac tctttcgcgg gaagcatcct ttacactgct
    26101 attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa gcttatactg cacaaatagc
    26161 tgtactaact ttattagcca aagctatcgg tgataaaaaa gaatttgaaa cttctcttgt
    26221 attcgatatc actcatgaat tgagtttagt tgctaatgcg atggaatcgg tcatcgccca
    26281 aaaagattat ttagaagagt tggcagaagt atatctcagc gatacaagaa atgcctttta
    26341 cattggacgt ggcgctgact acaacgtttc tcttgaagct gctttgaaat tgaaagaaat
    26401 cagttatatc caggcagaag gttttgccgc tggcgaattg aaacatggaa cgattgcttt
    26461 gatcgaagaa ggaacaccag tgattggaat catcagtgaa gaagtgactg gtgcgcatac
    26521 tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa acactagtta ttgtctcaga
    26581 gggattagaa aaggaaagtg accagctggt gctaccaact gtccaccctt atctaactac
    26641 tctaaccaca gtcgtaccga ctcaattact tgcatattac gcaacgctat tacggggatt
    26701 cgacgttgac aaaccacgta atttagcgaa atcagtgaca gtagaataat aaaagaacaa
    26761 ggaccagtgt cagacatctg acactggtcc ttgttctttt attttttatg aaaatatctc
    26821 ttaatccagt ccgatttctt ctttgactac tgccgcgatt ttatcgacat agtaattaac
    26881 tttctcatca gtaggcgctt ctgccatcac tcgaagtaat ggttctgtac cggaaggacg
    26941 aactaggatt cttccttctg atcccatttc agcttctgcc tcttcaatca cttttttgat
    27001 tgccggaaca tccatcgcac cgtttttatc acttactcgg atattcacta atttttgcgg
    27061 atagattgtt acctctgctg caagctctga taatttctta cctgtctgtt tcatgatatt
    27121 cagtaactga attcctgaaa gcatcccatc tccagttgtg ttaaaatcta agaaaatcat
    27181 gtgcccagac tgctcgccgc caaagttata atcgtttttg cgcatttctt ctacaacgta
    27241 acgatcacca acttgtgtaa cgacatcttt caaaccgatt ccttccaccg ctttgtggaa
    27301 tcctaagtta ctcatgacag tcgtaacgat cgtatctttt ttcaatcgat ttttttctgc
    27361 caagtattta gcacagataa acatgatttt atcaccgtcg acaatgtttc caagttcatc
    27421 caccgcaata atacgatcgc catcgccatc gaaagctagt ccagcatctg ctcctttttc
    27481 aacgaccatc tcagctaaac gttctggatg ggtagagcct acgccatcat tgatatttaa
    27541 cccgtctgga tttgtgccca tggtataaaa atctgtttca agatcggcaa acaaacgatt
    27601 aacacttgtt gaagttgctc cgtttgctgc atcgacacaa atggtcaaac cggaaaggtc
    27661 accgttgatc gtttgtacaa ggaattgaga atatttcaat aagccttctg gaaattcttc
    27721 tacagttccc aatccttcag ctgatggacg aggcaattca tccacttcag catctaataa
    27781 tgcttcaatt tctagctctt ggtcatctac tagtttaaaa ccatctgcac cgaaaaattt
    27841 gattccatta tcttgtgctg gattatgaga agcagaaatc atgacccctg cgcttgcttt
    27901 ttgcaaacgt gtcagataag caacacctgg tgtagagatc acacctagct ggaacacttc
    27961 gatacccacc gataaaagtc ctgaaatcag cgcttcttct aacatttgac ctgagattct
    28021 tgtatcccgc cctactaaca cgcgtgggcg ttttccttct tcttcatgct ggcttaggac
    28081 ataacctccg caccgtccca gcttaaatgc aagttctggc gtaagttcct tgttggcttc
    28141 accgcgtacg ccgtctgttc caaaatattt acccatagtt gtaaaattac tcctttaact
    28201 taattttctg aggaatttgt tctgctcatt tgtgttgatt cgcttgtttc tgatgtttct
    28261 tctgtacttg tggtcgagct gcttgtccca gattccgaac tggaagaaat ggttgttgtc
    28321 gatggttccg ttcctgaatc agcagatgaa atacttctac tcgtacttgt attttcttgt
    28381 gtccgactgc tcgtcgaagc agagctactg cttgacgttt gcaacacggg tgtaatctcc
    28441 acactaactg attcgggctt gatacttaac ccctcttcta ctggtatttc aattttacga
    28501 gttgttcgat gattgatacc tgagacattg atcggtacag caatactgtc accgatcgat
    28561 gcaagcaaat cgctagagcc gcttacttct gcttccagtt ttgaaaaact gaaatcatag
    28621 ctttctaccc cggcagctgg tgttccttgc tgtatcccat aaagtcgtac cgacttgctt
    28681 ggcttgatcg aatcagctct cactgttact tgcactggat cagagacgat acttaatact
    28741 tcccctgctg cattcagcgc ctgtattggg acctcactat taatcccatc atctgtgacc
    28801 atcgaagcgt ccacatcagc tactactcgt ttgatttctg ccaatgtttt gtcacctgta
    28861 gtgatagaga cttttttagg actaacggaa gtatcatcaa gttcatatcc agatggtgtg
    28921 aacgttgaag gaatcaacgt ttccacatcg aaatctttta ttaccttttt ctcaaccgtt
    28981 actgtaatag tcgatggttc gatctttgct gtgacagcac tgctcaaatt ttgaattttt
    29041 agcggaacct catgtgttcc ttcgcccagc ttagtgatat ctgctgtgac gcggaacatc
    29101 cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt ttgcactgga aagtttgaca
    29161 gtcactgcat tttcatatcc atggatatag tagcgctttg aatcataaga aatcttgatt
    29221 ggcaccccag taactgtttg attatacgct tcatttccag aaagcgtatt tggaacggac
    29281 tggccatttg cattgaagta cagcgcaata ctgaacagca atgcaataaa actgtaaaga
    29341 atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc tcccttagtc ataccgtcta
    29401 ggaaagattg aatcacgttt ttcttgtttt ttgttttctc ttcagcaatc agttctctac
    29461 gcaaaattgc caaatattct tgctgggata agccagccat cagttcatta tctaatgtaa
    29521 tgctgacatc cccagtttct tcagagacaa cgatggtaat cgcgtcgctg acttcgctta
    29581 taccgacagc tgcccggtgt cgagtcccga attcttttgg aatcaacata ctttctgata
    29641 gaggaagata ggcgcttgct actgcgatct ttccttcttt tacaataact gcaccgtcat
    29701 gcagcggtgt attaggaata aagatattga tcagcagctc tccagtgata tctgcatcta
    29761 atgcaattcc tgtctcaata tactcatcta atccagtatg ccgttcgata gtaattagcg
    29821 caccgatttt tcgcttggac atatattgga tggctttgtc aaaagacaag atcatcttct
    29881 catcttcctg ctgttcgctt tttgattgtt tgaaaagcga actgcgtcca agatgttcca
    29941 gtcctctccg gatttccggc tgaaaaatca cgatagcagc tatcaccccg tacgtaatga
    30001 cttggttcat cagccaagac aaggtgtgca gaccaatgat ttccgctacg attcggataa
    30061 caataaaaat agctacacct ttcagaagct gaatcgcttt tgtgcctcgc agcagttgga
    30121 tcagtttgta tacaagatac cagacaacca gaatatcaag tatgttcacc aaaaaattca
    30181 gagagaacaa gtcaccggaa aacatttgct gccaatagtc caaattaaaa agttccccga
    30241 tttgaaatga cataaaaagc ctctcttctc ttttgagatt tcctctctag tatatcatat
    30301 gttttaattt tagaggctga tctgctcgta tttttcttga gaaaaacgca taattttcag
    30361 gaaaattgca agtatgcgtt ttatttttct ctgcaataaa tatttttaaa cttcagagaa
    30421 ttattcatta tattttttct gttatttttc ctttttttct tttgtagctt gttccatttt
    30481 tttacgtcgt tctgctctgg cagctcttct ttcttctgct tcaaggtccg tcgttttttc
    30541 ttttctagtc ttaacgggta catcgataga ttcctctggt tcaagtcgtt tcttgatttt
    30601 ttctaattct cccgtcagtg cagcatagtt gtaaaaacgt gttttagcgt cttggatagt
    30661 cttttcaaat aaagcttttg caagatttgg atttgcgttc tctagcgagg aaaagcgaac
    30721 ttgtttcctc atgaaatcag gcatagcaga gaaatcaggt tttttgtagt ccaaagtcat
    30781 tgggttcttg tttttttcga ccattgcagg gttatatcga tataatgacc aatagccaga
    30841 agaaacagct tcttttgctt ctttaagcga ttctttcatt ccaccaagca aaccatgtgt
    30901 gatacaaggc gtataggcaa tgattaaaga aggtccagga tacttttctg cttcttcaaa
    30961 agcctttatc gtctgcattt gattggcacc tgaagcaatt tgcgccacat aaacatttcc
    31021 atatgtcatc gccatcattc ctagatcttt ctttgaagca tactttccac tagccgaaaa
    31081 tttagcgatt gccgaagctg gtgttgcttt tgaggtttga ccgccagtat tggaatagac
    31141 ttcgttatcc aaaacaagaa tattcacgtc tgctccgctg gcaagtacat gatcgatccc
    31201 gccaaaacca atgtcgtaag cccatccgtc tccaccaatc atccattggc tgttttttac
    31261 gaatagatcc tttctcttgt atatatcctc cagttcaggg acaattgatc gttcgctttc
    31321 gatcgcagct tgcagttttg ctgctctttg ctgcgttcct tcgctctcaa acatgtgtac
    31381 caaccagtct tccatcaatt ctcgtagttc ttctgatact tttggcaata cttctttgat
    31441 tgaacttgcc aaagcctcgc gacgagtctg tgccgctaga agcataccat aaccaaattc
    31501 agcattatct tccaataaag aatttgacca tgcaggccct tgaccacatt cattggtcgt
    31561 ataaggagaa gcaggagaag caccgcccca aatagaagaa cagcctgtcg cattcgcgat
    31621 catcattcga tcaccgaaca tttgtgtcaa taattttaca taaggtgttt cgccacagcc
    31681 tgagcaagcg cccgagaatt caagaagcgg ttgattgaat tgtgtagaca agacagtatt
    31741 ctttcctttg actggatttg ctttttgtct taatgtcatt gcaaaagccc aattcacagc
    31801 ttgttctttc tgttcttcat aaggcttcat cactaaagct ttttcttttg cgggacaagc
    31861 ctctacacac agaccacaac ctgtacagtc ttccactgaa acttggatac ggtattttac
    31921 gccgtctgcg cctcgcattt ctctcacgat aaatccttct ggcgcttctt ccatttcctc
    31981 ttcatctgct aaaaatggac ggatggcagc atgaggacaa acaaaggcac attcattaca
    32041 catcgtacag cgatcactaa tccactcagg tacttctaaa gcgacgcccc gcttttccat
    32101 agaagccgtt cctaaaggca tttcgccagt tgtcattcca tttgctacaa gtgtaccaac
    32161 agagagttga tttccttcct gtgcattcac tggttcaagt atttcttgta tataaccagt
    32221 gttcctttta ttgatttttt caggcatctc caacgttctc caatggtctg ggatcgcgac
    32281 ttgatgaagc agttcggtcg tccgatcgat tgcttgtatg tttttttcta cgatagccat
    32341 tgatttatgt ccatagcttt tcagggcttc ttcttttagc agcggaagca cctcatcaaa
    32401 aggaatgatg tcagctaatt taaaaaaagc cgtttccatt gccgtattga tccggcgtcc
    32461 caaaccgact tcttgggcca atctcatggc attgatcgta tagaatctaa tgttattttc
    32521 agccaagtaa cgttttaatt ttaagggcag atgcgtttct aattgttcgt cgctccaaag
    32581 agtattcaat aaaaaaatgc cacctggctt caatcctttg accaagtcat agctatgcag
    32641 gtaagctggt gtgtgacagg caacaaggtc cgcatgctcg acaagatacg ctgaacgtat
    32701 cggcgtatct ccaaaacgaa gatgagagac agtcagaccg ccagattttt tcgaatcata
    32761 ataaaaatag ccttgcgcat atttatcggt gtgatctcca ataatcttga tagctgattt
    32821 atttgctcca actgttccgt cagatccaaa tccccaaaac ttggcctgga atgtttgcgg
    32881 ttctgtcaaa tccagacttt cctttggttc caaagattga taagtcacat catccacgat
    32941 ccctatggta aaccgttttt tgcgtatgct tgggtctttt ttcaattcat caaaaactgc
    33001 tgagatttgg tcgggagtca catctttaga ccccaatccg tagcgaccac caataacagc
    33061 cgggcgaagt tcagaatcat ataacgcact ttgaacgtct aataagagag gttctccacc
    33121 tgcccctggt tctttacttc gatcaagaac agcaattgtt tttactgtat gaggcaactt
    33181 ttgcacgaat gtttccactg gaaaaggacg ataaagatgg atattcaaaa aacctgtttt
    33241 ccgtccgttt gcattcaagt aatcaatcgt ttgttcaatc gtctgtgcaa ctgatcccat
    33301 agaaacaatg acttcttccg catcgtctgc tccgtaataa gtcaccaagt cataagaagt
    33361 tcctcgtaat cggttgatct ctttcatata tttttgaacg atttcaggta atttatcata
    33421 ataggggttg atcgtttccc gttgttgaaa atggatgtct ggattctggt tcgtaccact
    33481 aacagtcgga tgattgggat tcatccctcg tttacgaaat gaagctaatt tctcctgatt
    33541 gatcagagga gctaattctt catattccaa aacttcgatt ttttgaatct cgtgactcgt
    33601 acggaatcca tcaaagaaat tcaaaaaagg tacttctcct tcaatagaag caagatgggc
    33661 aacaggtgct aaatccatca cttcttgtac actgctttca gctaacatag caaatcctgt
    33721 ttgtcttgca gccatcacgt ctccgtgatc tccgaaaata ttcaacgcat ttgtcgtcac
    33781 tgcccgacta gcaacatgga aaacacttgg cagtagttcc ccagcaatct tgtacatatt
    33841 cggtatcatc aaaagcagcc cttgagaagc ggtatatgta gttgtcagtg caccagtttt
    33901 caatgatcca tggaccacac cagctgctcc tgcttcggat tgcatttcta ctacttttac
    33961 tggttgaccg aatacatttt cttttcctgc tgctgaccat tgatctacta attcagccat
    34021 ggtcgaactg ggtgttattg gatatattgc agcaatctcg gtaaatgcat aagaaatata
    34081 tgcggctgcc gtattgccat ccattgtttt catttttcgc atgattcatc atccttgttc
    34141 atattctctc ttattatctg ttccattata acgtaaaaca ttccattttt tcttttattt
    34201 ataaaaatat ttcacatatg tctatttgaa ttggtcatct aatttttaga caaacagtct
    34261 aaatcgttgc ctttttttgt cagacatgta taaactataa gcgaaagagg tgttttaaca
    34321 tggatatatc agtgattgat gcaacgaaaa caaatacaca aaaaggaatc ctttatggtt
    34381 catcgaatgc tcctaaaaaa atggtcgaat tcatcaacct atcttgtccg tattgccgac
    34441 aatggtttga agaatcttat gagctattag aagaagcagt ccaaagcggg caattgcagc
    34501 gagtgatcaa attgttcgat aaagaaaaag aaagcttgca gcgaggaaac gtgatgcacc
    34561 ggtatctcac aatcagcgat ggtcaaaaag cgatcaaaga gatcaaacaa atattcgata
    34621 ctcaagacga gtggaaacat ctttctctcc aagaagtagc ggattttgca gtagataaac
    34681 taaagctgac agaacaaaaa gacgaacagc tgagccaagc tgtcatcaac gaagctgagc
    34741 aagcacatat tcgatttgtt ccgactgtca tcttgggtaa agaaatcttt gatgaatcta
    34801 tttcaataga ggaattaaaa gaattgatcc aaacaaaata aaaaaataag gagcgtagga
    34861 caaaagtaaa gaacactttt gtctcacgct ctaaacacct ataaacggcg gaagcagaag
    34921 caactccttc ttatttcttg gagttaaacg cttctgtccc agcctcctta ttccgaataa
    34981 atggtgtcca aaagcttgca tctgccagat tatctcattt cttatgacaa gctgagcaaa
    35041 ttatctccac caaataattt attcatattt ttgacttgcg catactaact aattcttaaa
    35101 ttttcataca aaatttctca aattccctta acgagtaata tttatgtacg gtgattcaca
    35161 ctagtatccc aatcactttt taagttatcc cgatttcaat tctacttcaa aaatagttgc
    35221 ttttatgtat gctgttagtt gattagatgg tcgtttgttg agctaggtcg tttattttaa
    35281 acaagttgtt tctttagctt atacctatct cgtctaccaa acgcaagatg gcaaacacaa
    35341 atgcatacgc atctgtattt gccactttga ttcgtataaa gctaacaact cctaactcct
    35401 ctcatttaat agttgctctc ttttttattc agatacattt ttgctgatca cagcctagta
    35461 tttcaatggt tttgaacact aaaccaaatt gttccattac aacattcact ggctgatgaa
    35521 atggattaat agatttcgat tattcaaagc gattttctat tggtggattg tgttcccaac
    35581 taacaagacg gattccaaag tcattatata actcttcaag agttaaccct ttcctgttcc
    35641 caatagatgt atctctccca cgctcgatat aaaatatgga gtttcgaatg ccaagacctg
    35701 gcaaatcttt ccttgttaca gttacactgc tactaacttc cccatataaa atccagctcc
    35761 tccaaaatga taatatattt ttcgaccatc atctaactca tgtaacaata attgttgtgc
    35821 cctcttgtca ctcgccaaat gcaaacgcca cgtgcgatac catgccatgc tacctgcatc
    35881 tgcagaaaat ccatcaaata atgcaacaat tgtatcttct atcacaatcc tttccccatc
    35941 tacttcatat tctaatctaa aatcaaactc ccctcgggta atcgcaggtc ttggtggctt
    36001 aggacccaat attattctac ttaaaaccgc attcgttccc agatgaaaca cagctataac
    36061 aacaataatg attaatattt tgtttctatt tgataaattt ctcattattc gcaaatcacc
    36121 tctacattct cacatactag ttcgtaatac tcctttaata tcaaaatatc tactgatcgt
    36181 aataatattc gctatgaatt cctactactc gtataagaaa ggccaaatca tcagctttta
    36241 cttgctgatg atttggcttg tttctattta tcgtaattgt tttctaatca ccaaaattgt
    36301 taacaatcgg ttcagatatt tcccaattca ctagccttat attatattga tttaacaatt
    36361 cttcttcatt tattgtattt tgatcaagcg gaccaaattg ttctaataat tctttgtcat
    36421 gtaaaatatc ccttctagta atgcctcttt ccctttcaat gaaagaagca ctaggaaaag
    36481 tatgattata accattcaac ctatctccca tgtaataatt agcaggtcct ggaaaataaa
    36541 atatttgctt attatcacta acttctaaca gcaacactaa atcttctccg ctggctaaac
    36601 gacttgtcca tctacgatat ctccctatgc cttcgttcat tccaaatcca tcaaattcaa
    36661 ctattaacgt gtcttctatc acatgtaatt cttcattcaa ttcatactca agtctaaaag
    36721 gaaattctcc atatgtaatc tctggcaatg gtggtgctgg agttctccaa ataaatacaa
    36781 taactgtgaa tagaaaaaat ccaacgatcg atataaatgt tatgagacct gctcgaagta
    36841 aaacccgata taataaaaat gctgtatttc gctttgctat atctagaaaa ataaaaagta
    36901 ctgcaatcat aatgatagta aaagttgtaa aaaaacgcat ttttgccctc cctttataaa
    36961 catcgattct caaattctaa accaaatctt ggtagttcaa gttcaggtat aacgtattcc
    37021 aaccatacat ctcaattact atttatgaac ttatgattat cactgaataa atcactccat
    37081 ccccttgtta aaacttctac attaattaca cctggttgtt ttcgactagc taatccaatg
    37141 aacttatcaa ccatccttat ccaccaacca cgagaatctt gaccagaagt aagaagagca
    37201 gttctcaagg atgatcgagc agttccttcc agttttttaa ttaatcaggc cagttataga
    37261 taaatacttg atcttatcta tatcaggact tctatattaa gcaaaaattt atgtacaaaa
    37321 ctaaaatctt cattcagttg tctccccgct ttttatacga ttgtattaaa aacaatagaa
    37381 gcctttccaa attatgttac tccagtaaag atggaattat agtttgacgg aagaaaagca
    37441 agtataactt ttaaaaaaaa ctgatacatt cgcatctcct gcttcatgta tcagtttttt
    37501 ctttggatta aactgcttct tcacgcagtt tttccgcaaa ttcatttatt ttgcgaattc
    37561 ggtgattaat tcccgatttt gatatcgcac ctgagggaat catttcccct aattctttca
    37621 agctgacctc tggatgttga agccgaagtt ctgcgatttc ctgaagtttt tcaggaaggg
    37681 catgtagacc gacctttgct tcgatcaatt cgatgttttc gatttgttta gaagccgcat
    37741 caatcgtctt gttcagattt gctgtctcac aattgactag acgattgacc gaatttctca
    37801 tatcccgtac gattcgaaca tcttcaaatc ggagcattga gttggttgca ccaatcaatg
    37861 ttaagaaatc agcaattttt tctgctcctt ttaaataaga aatatagcca ttgcgccgtt
    37921 caagcgttcg agcatgtaga ccgtaataat ttaacatatc gcaaatgtct tggttatgct
    37981 gttcataaat agaaaatatt tccaaatgat aacggctcgt ttccggatta ttgactgaac
    38041 ctgaggccat aaaagcacca cgtaagtaag aacgcatttt ttgcgaattt cccataatct
    38101 cgtccgaaac gtgtccattg aacatcatac catccatgat atcaagatcc atcaacacat
    38161 cttttgtgcc ttgcttcaac cggacgatat agacattgtt cttttttaat ttcatttttt
    38221 tacgaacgag tagctcactt cgtacctgat aatgatcttt caaaagagaa tagatacgtc
    38281 tggcaattgc agcattttct gtttggacgt tcaaaataaa ctgctggttc acaataccta
    38341 aagagccgtt cattcgcagc aaagcagcta attccgcttt cgcatgttct cgatgaactt
    38401 ccaaaccagt tagttctttc ttcacatctg cagcaaatga catcctattc tcctcctttc
    38461 tccaacaata aattgcttaa tattttgaac cgaaaactaa acggaacaat tcttctacta
    38521 ctttgtctcc atcgtggaag acaccaccat ctttcaattc caaaaagtcg gtggaaatca
    38581 ctcgacatcc ttcatttctc aatccgttga agtcgtgtgc gacttgtact agatactcat
    38641 catagatctc tgggtccata taatcttcag gcactttttc cgtattgacc aatactgtat
    38701 cgataaaagg ctgattcaaa tgcttgtgta aaacacgtat atgatcggca tctgtgaaat
    38761 gttccgtttc ccctttttgg gtcatgatat tacagatata gacggtttca gcagttgtct
    38821 tgagcattgc ttcgccgatt tctggtatca ctaaatttgg aaggatactg gtgaataaac
    38881 ttccgggtcc caaaacgacc atgtcggcgt ccataattgc tgaaacgact tttcgagccg
    38941 ctttggcttc acttttatca tttgtgttgc agacatacac acggtcaatg gttttacggt
    39001 cgatcgcgat tttagattct cctactgcag tcgttccgtc tttaaagaca gcatgcaagg
    39061 tcaaaggagt ttctgaagaa ggataaacat gtccatctac atgcatcatt tttgctaata
    39121 attgaatcgc ctcataagtg cttccccgca tctcggaaac tgcggcaatg atcagattac
    39181 cgatcgtatg attggctaaa aactgatctt cctttttgaa acggtattgg aaaatatctt
    39241 catagaattg tggcatatcc gataacgcca ctaagacatt tctcaagtca ccaggaggag
    39301 ccatagcgat cgattctctg attgcaccgc tgcttccccc atcatctgca acagtcacta
    39361 ctgctgtgat atctgctcct tgatttcgca aacttttcag gataactggc agaccagtgc
    39421 caccgccgac cactacgatc tttggttttc ttatccggta ggttttcatt ttcacgaccg
    39481 gttcaccgtc tctttccttt tatccttgtc ccgatgtgtc acattgactt tatagttttt
    39541 ccctaaagca tttgccaaac gttcagtcaa tgccacagaa cggtgttgac cgcctgtaca
    39601 gccgattgca actgtcaagc tgctttttcc ttctttaatg tatccaggca atacagtttc
    39661 cagaagatcc aaaaatttat ggtagaatga ttgcgtttca tcaaaggaca tcacataatc
    39721 atagactggc tgatcttttc cggtcaatgg tcttagttcc gggatataat gagggttggg
    39781 caaaaaacgc acatccatca caatatccga atcgatcggc aacccgtatt taaaaccaaa
    39841 tgatacaaat tcgatccgaa atccttggtc tccctttgat ttgaatgact cattgatttt
    39901 ttcacgtaat tgtcgtggtg tcaatgtcgt cgtatcaatg atcacggaag cttgggcttt
    39961 caagtcgtct agtatcgccc gttctttacg tatcccttca gtgatcaaac cgtccatcgc
    40021 cattggatgt gctcgtcttg tttctttgta gcgagccact agttcttcgt ctgaagcatc
    40081 taaaaataag atagaagtgt cgatgaagtt cgtattttcg atttcgatca gcatgttttg
    40141 gatttcttca aagaaggaac gagaacgtaa atccactcct aaagccattt ttgtgacttt
    40201 gcctgattct ttgattaatt cccagaattt tggaatcaat cgaggcggca tattatcgat
    40261 acaaaaatag cccatatctt caaaactttg gatagctact gttttccctg caccgctcat
    40321 acctgttatg atgactaatt gcaaattatc tgtcataatt acgaactcct ctcacattgt
    40381 gcatagtaaa attatatcat tccgggcgta tcattaccag ttttcttttt cttttacaaa
    40441 aagatttgga ccaaatatct tttaggatat ttgccccaaa tccaattttt ttacttttcc
    40501 gatgctgtat ccaatgcctt gcttctttca gctagcgctc gttcaatcgt ccgatctgct
    40561 aaaatagatt gggcatcgat cactggataa tggttatctt cagcaaattc atgcatcaat
    40621 gacaattctg tgcaacctaa gataactttt tcacagttta ggcgctctac cgcttcttct
    40681 aagatttcgt aatatagctc ttgattcaaa taatccgatt ccttgatctc atgatagatc
    40741 agataattga ttttttcttg aagaacagta tcaggaatca ctgtttcgaa tccaagattt
    40801 ttgacttcgc gttcatagat tccagctttc atacttcctt ctgttcctag aatcgctact
    40861 ctccctgtcg tatgctgacg gacaagttca tttgctgctt ctcttggcat atgaaggata
    40921 ggaatatccg ttgccgcttg taattcttca aaaaagtagt gtgcggtgtt acaagtcaac
    40981 acaatgaagt tcggctgcaa taaattttgt ttctcaatat catccagcag aaacggcatt
    41041 ggattttctt ctgatcgatc taaaatataa gctgtacgat caggaactgt tgcatgattg
    41101 aataagacat aattcaaata ttcttgatct tttgtagctt tcgttcggtg gttgatcaag
    41161 cgaacaaaac tttctgtcgc catcgtgccc attccgccta aaatactgaa aaaattctcc
    41221 atgaactagc cttctttcac atgaaaatac tttttgaatc ttggaatata gttatggaac
    41281 atatatttca tcaacaacca gcgcttgatt gaccggtctt tttcataaaa cacagtagta
    41341 ccgtaacgat tttctttgat catttgctca gctagttttt tgtcttcatt ttcccgagca
    41401 tattctaaaa agattttttt gggcacaccc atccataatc ttgctttatc tgattgattc
    41461 gttccatagg tcgtttcaac aaagggtttg ttaaacactc gatcttctgt gacgaaacga
    41521 gccagattca agccgttcaa tgtcacaaag aaactgctac gaccttgtct caaattgatt
    41581 tcaaataatt tatattctcc atctctagga tcatacttca tatcgaaatt ggcaaagcct
    41641 gtatattcga ttttttccaa aaatgcctta atggtttgat agattttttc gttataatct
    41701 ggcatgatca caacgtaatt accaatcgat gctggtgtag gatcttctaa cagtggatga
    41761 ccaagacaca tcatccgaac ttgatgatct tcatctacat acgcatttag cacacgcata
    41821 ttactatcat cacccgggat aaaatcttgt acaatcattt cacttttata accggcttcg
    41881 tatatccggc ctaaaattaa atcgaactct tctctagtct ctaaaataaa agcttttttt
    41941 cttccttcaa attggacaga aagatactcc acactgtttg caggtttcaa agcaactggg
    42001 aattcaaaag gcaattcctg ttccaaatgt ccatttacta acatttcttc tctgacgatc
    42061 aatgttttag gatacggaag atcatattct tcacaaactt cataaaagct tactttattg
    42121 atcagtcttt caaataaaga ataatcaata tatggacaga taaaatattc tgacagctct
    42181 tgtttatgtt gggagatcaa ttctgcatat ccatcaccac aagcaatcaa aagatatttt
    42241 ttactcttat cagaatatct ttcttttgcc aaacgaagca tcgtctcgat aaacacaggg
    42301 tctttatcaa atcctggaat aacttctaca ttgacaattt tactgtagcg ggtaggggct
    42361 aactgatccg aagcatatgc ttggcagatt ttgccgtatg cttcattaaa agaacgtgcc
    42421 ataccataaa cgttcatgtc gcttcctaat aatataggga taaattcttc attttcaata
    42481 ctgttcatca ttatctctca cttactcata atctcttgtt tttcttttcc aactacacaa
    42541 ggaatatcat accataaaga aaaaagcaat caaaggaaac tcctccgatt gctcaattct
    42601 tttttgaacg gattgaactt ataggaagtt tttgtctata ccaatcagtg tagaaagaac
    42661 taccatgtaa tgattctaga acactgatat taataaaaca agcaaaaatt cattttttta
    42721 tgttttttta actatctcag ctatctatcc tctttatacc attatttttt tcaaatagtg
    42781 acctgtataa ctttctttta cgttaatgat ttcttctggt gttccagtcg caaggatcgt
    42841 tcctccacct tctccacctt ctggtcctaa atcaatgata taatctgctg ttttgattac
    42901 atctagattg tgttcaatca ctaaaactgt gttaccagca tctactaatc tttgtaatac
    42961 atgcaacaag cgggcgatgt catcgctatg aagtcctgtc gttggttcat ctagtatata
    43021 gaaattcttt ccattagaga ttttgtgcaa ttcactggca agtttcatcc gttgtgcctc
    43081 accaccggac aatgtcgttg ctggttgccc catcgtcaca taacctaagc caacatcaac
    43141 aatcgtttgc agtttgcgat gaatctttgg aatgtgcttg aagaattcta cagcatcttc
    43201 tactgtcatt tccaaaatat cagcaatgct ttttcctttg taatgcactt ctaatgtttc
    43261 agagttatat cgtttgccat gacatacttc acaaggaaca tagacatcag gcaaaaagtg
    43321 catttcgatc ttaataattc catccccgcg acaagcttca caacgaccgc cttttacgtt
    43381 gaaactaaaa cgccctttct tataaccccg catttttgcc tcgttcgttt gagcaaataa
    43441 cccacggata tcatcaaata cacttgtata agtcgctgga ttacttctcg gcgtccggcc
    43501 gattgggctt tgatcgatat cgatgatctt ttcgatactt tcgtagccgg aaattgtctt
    43561 gaatttacct ggcttagcag aattcttatt taatttttgc gctaacgatt tctttaagat
    43621 actattgacc aatgtactct ttccagaacc agacacacct gtgactgcta caaattctcc
    43681 taatggaaat tcaacactaa tatttttcag attgttttct gaagcaccag tgatcttgat
    43741 tgctttccca ttacctttac ggcgttcttt tggtacaggg attgattttt tccctgaaag
    43801 atatttccct gtcaaagaat tttcatcatt agctacttct tcaggagtgc ctgcagccac
    43861 gatttgtccg ccttgttctc cggccccagg tccgacgtca atcagataat ctgctgccca
    43921 catcgtatct tcatcatgtt cgactacaac gagggtgttg ccaagatcac gcattttctt
    43981 taatgagcca atcagtcgat cgttgtcgcg ttgatgcaat ccgatcgatg gttcatctaa
    44041 aatatacaaa actccagaaa gattcgatcc aatttgtgta gccaatctga ttcgctgcgc
    44101 ttctccccca gataatgttc cggaagcgcg actcaaagtt agatagtcta gtcccacatt
    44161 ttccaagaat gaaagtctgt catttacttc ttttaaaatc ggtttggcaa ttactttctc
    44221 ttgttcagat aacgttaagt ttgagaagaa atctactgct ttttgaatag acaactcatt
    44281 tgtttgcccg atattcgttc cattgatttg aacagataga gcttggggat tcaatcgata
    44341 acctttacat gtctgacaag ttaattctgt catataaaga cgcatttgct cacgcgtgaa
    44401 atcactgttc gtatcatgat aacgacgctc gatattcttc aatacccctt cgaaagtcgt
    44461 ttctacatcg cgaacgccac caaaatcatt ttcataatgg aaatggaaaa gatcatctgt
    44521 cccattcaag atgatatcct gatgctcttc cggtaattct tcgaatggtg tatctaaatc
    44581 gataccgaaa ctttcacaag cctgcgctaa catttgagga taatactgag agctgattgg
    44641 attccatgga acgatagcac cttgactaag tgtcttcgtt ctatctggaa tcactaaatc
    44701 ttgatcgact tctaatttga cacctaaacc atcacagtct ggacaagctc caaaaggcgc
    44761 attgaatgag aacagtcttg gttctagttc gccaacagta aatccgcaat aaggacaggc
    44821 atagtgttcg ctaaacaaca tttcttcttc accgatcacg tcaaccagag catagccgtc
    44881 tgccaatcgc agagccgcct ctaaagaatc aaatagacga gaacgaatcc cttctttcac
    44941 aatgatccgg tcgatgacga tcgcgatatc atgttttttg tttttctcca gctcaggcac
    45001 ttcacttaaa tcatagatct caccatcgac tcgaacgcgg acgtatccct ctttttggat
    45061 tcgttcgaat atttttttat gttgtccttt tttctttacc acgatcggtg ccaacacttg
    45121 gatctttgtg cgctcaggca aagccattac ttgatctgcc atttgatcta ctgattgact
    45181 ggtaatctcg atatgatcgt tgggacaaat cggatgtcct acacgtgcaa acaacaagcg
    45241 taaatagtca ttgatttccg tcacagtacc tactgtcgac cgaggatttt tacttgttgt
    45301 tttctgatca atagaaatcg ccggactcaa tccgtcgatg ctatctacgt ccggcttatc
    45361 catttgtcct aaaaactgac gagcataagc agaaaggctc tctacgtatc tccgctgccc
    45421 ttcagcgtac agcgtatcaa atgctaggga actttttcca gaaccggaca aacctgtaac
    45481 gaccacgaat ttatctcgtg gaatcgttac atctatattt ttcaagttat gggcacgtgc
    45541 accgtgaatc gtaattttat cgttagccat gttgtcctcc tactttgaag cttttaattc
    45601 taaaatcata tctcgcacat tagcggctgt ttcaaaatcc aatgctttcg ccgcattttt
    45661 catttctttt tctaatttca tcaataacgt atctttttct tctttcgtca tttcttcata
    45721 cgagacttgt accgcttctt ttgtatcatc ttccgattct ttcgtaatag aaatcaaatc
    45781 tcggatttct ttaatgatcg tttttggaac gatcccatgt tcttcattgt acttctgctg
    45841 aatcgtacga cgtcttgacg tttcatccat cgctagacgc atagaatctg ttactttgtc
    45901 tgcgtacatg attactttac cttcttcatt ccgagcagct cgtccaatcg tttggactaa
    45961 ggaacgttca ctacgtaaaa agccttcttt atccgcatcc aagatagcaa caagggaaac
    46021 ttcaggtacg tctaatcctt cacgaagcaa attgattcca actaacacat caaattcacc
    46081 taatcgaaga tctcgaatga tttctgttcg ttccagcgtt ttgatatcac tatgcaaata
    46141 tttgactttg atccctaatt ctttgaaata atctgtgagg tcttctgcca tttttttcgt
    46201 caatgtcgtt acaaacaccc gctggtcttt ttcgactcgt tcatttattt cgcctactag
    46261 atcatcgatt tgtcccatga ttggacgaac ttcgatcact gggtcaagca gccctgtcgg
    46321 acggatgatt tgttggataa cggtatctgt ttgttcatgt tcatatggtc ctggcgtcgc
    46381 agagacataa atgatctgat tgacatgttt ttcaaactct tctaaccgaa gtggccgatt
    46441 gtctaaagca gatggcaaac ggaaaccgta atctactagc atctgttttc tcgctcggtc
    46501 accattatac attcctctga tttgaggcat ggttacgtgc gattcgtccg ccacgatcaa
    46561 aaaatcttca ggaaagaaat ccaatagcgt ataaggcggt tcaccttctt tacgtccgtc
    46621 catatgccga gaataatttt caattcccga cgtgtagccc atttctaaca tcatttcaat
    46681 atcgtaattg gttcgctgtt ctaaacgttg agcttccaga agtttgtttt catttcgcaa
    46741 gacagttaaa cgctgttcta attccgcttt gatattcgct acggcatgct ccatatgttc
    46801 atcattcgtc acaaagtgag tcgccgggaa gattgctacg tgttccgttt ctcctaaaac
    46861 ttcacctgtc agtgcattga cttctcggat acgttcgacc tcatctccaa aaaactccac
    46921 acgtaaggca cgttcatctc ttgaagccgg aaaaatctcc acgacatcac cgcgcactcg
    46981 aaaacgaccg cgctgaaaat ctatatcatt tctttcgaat tggatactga ctaagtcacg
    47041 aatcaactga ttgcgatcta gttctgctcc ctgtcgaatc gaaactactt gtttttggta
    47101 ctcaaaaggc gagcctaatc caaaaataca tgaaacggat gcaatgacga tcacatcatt
    47161 tctttctaat aatgaactag tagccgaatg tcgtaatttg tcgatctcat catttacact
    47221 tgaatctttt tcgatatacg tatcgcttga aggcacataa gcttcaggct gataataatc
    47281 ataataagaa acaaaatatt caacagcatt gttagggaaa aattccttga attccccgta
    47341 cagctgacca gccaatgttt tgttatgggc aataatcagt gttggtttat tcactttctc
    47401 aataagattg gaaatcgtat atgttttccc tgttccagtc gcacctaata agatttgtgc
    47461 ttttttcccg ccgactacgc catccactaa ttggttaatc gcttcaggct gatcaccagc
    47521 cggttggtat ttcgagacaa gctcaaagtg tcgggaggta tctctctcaa tcattcttcg
    47581 tcctcctttt cattcattcc ttttcatttt acgaccaata aaaagaaaag gaaagcaaag
    47641 gcattcctta ctaaaaaatt ataccacacc gaacatactt tcgccacttt tttatcttat
    47701 tatacatgtt atgttttata acataaaatg ttagaaactc gcattttttt cattttttcg
    47761 agcttacagt cttgtctgat tcagcacttt tcgcctataa taataaaata ttggaaattt
    47821 aggaggttga ttatgaaaag aaagcattta tttcactcat ttgttttctt aatgacagga
    47881 cttgtgacac ttgcgtttgg tcatgttgca caagctgaca acactacaac ggcagagtca
    47941 agcacaagcg agacaatgca aaaaatagag cccaaaaaag acgtatacgt aattgccagt
    48001 gactctgctt ttgctccatt tgaatttcaa aacgcaaagg gcgagtacga aggcatcgat
    48061 gtaaaattga tggaaaacat cgccaaactg caaggattta acatccgaat ggactaccgt
    48121 ggtttctctg ctgctttgca agctttggaa tcaggacaag cagacggaat gattgccgga
    48181 atgactgtaa cagatgaacg aaagaaaagc tatgattttt ctgattctta ctttgatagc
    48241 gggatccaat tagctgtcaa aaaaggagat acttcgatca agtcttatga agatttgaaa
    48301 ggaaaaacag tcggagcaaa agttggtacc gaaagtgctg aatttttaag cgaccatgaa
    48361 tctgaatatg gctattctat caaatatttt gatgctgctg atcaattgta cgacgggtta
    48421 aaagttggcg caatcgatgc aatgatggat gattatccgg taatcggtta tgcgatcaaa
    48481 caaggacaag aattggaaac accgatcaaa aaagaatctg gcggaaaata tgcatttgcc
    48541 gttaaaaaag gacaaaatcc tgagcttctt aatatgttca atgaaggatt gaaagaatta
    48601 aaaagaacag gcgaatacga taagattatt aaagaatatg tagcggatgg ttcagaaact
    48661 tccagtgagt cttccactgc tgatgaatca acatttcttg gacttatcca aaacaactat
    48721 caagcattgt tgaaaggact ttggagaaca attctcctaa ctttgatctc ctttgctttg
    48781 gctatagtaa tcggtgtgat ttttggatta ttcagtgtag caccaatacg cgctcttcgc
    48841 acaattgcta gtatttatgt cgatatcatc cgaggaattc caatgatggt tcttgcgttc
    48901 tttattttct ttgggttgcc tggtatcgtt ggatttacga ttcctgactt ccttgctggt
    48961 gttatcacct tgactcttaa cgcaagtgct tatatcgcag agattgttcg aggcgggatc
    49021 aacgccgttc ctgtcggaca aatggaagct tccagaagtt taggtctttc ttataatcgg
    49081 acaatgcaaa aaatcatttt gccgcaagcg atacgcatca tgatcccatc attcgtcaat
    49141 cagttcgtta tctcattaaa agacacaacg atcatttccg caatcggtgt agtcgaattg
    49201 ctgcaaactg gtaagatcat tgttgcacgt acaacacaaa gtacgtatgt ttacttgatc
    49261 attgcgatca tgtacttgat tttgatcaca gcattgacaa aattagcaaa agttttagaa
    49321 aagaaggtga agtaagatgg cagaaaaaat cttagttgag catttagtca aaaaatacgg
    49381 cgataacaca gtattaaacg acatcaatgt atccatcaac gaaggagatg tcgtctgtat
    49441 cattggccct tcaggttcag gaaaaagtac attcttgcgt tgcttgaatc gtttagaaga
    49501 accttctgac ggtgaaatta ttattgacgg cgcccacttg atggataaaa gcacagatat
    49561 caacttggtg agacaacata tcggaatggt attccaacac tttaacctat tccctcatct
    49621 ttctattttg gaaaacatca ttttagcacc gatggacctg aagaaagaat ctagagaaga
    49681 agcagagaaa aaagcaatca aattactgca gacagttggt ctagaagata aaaaagatat
    49741 gtatcctgaa atgctttctg gtggacaaaa acagcgtgtg gctattgctc gtgctctagc
    49801 gatgaaccct gacatcatgc tttttgatga gcctacttct gcactcgatc ctgaaatggt
    49861 cggtgatgtc ttgaacgtca tgaaaaagtt agcagaacaa ggtatgacga tggttatcgt
    49921 tacgcacgaa atggggttcg ctaaagaagt ggccaatcgc gtcatgttca ttgacgacgg
    49981 aaacttttta gaagatggaa cgcctcaaca aatctttgaa aatccgcaaa atgaacggac
    50041 aaaagatttc ttgaataaag tattaaatat ttaataaaaa ccaaaaatgc acggtcgcca
    50101 tgaagggacc gtgtattttt atcttcttat tttctcacct aatcgtatca gccgcatcgc
    50161 ttgttttcct gcacaaacaa gcaatcgctc tacctgttcc atcgcataag aaagtaccat
    50221 cggttcattg atgatatcaa gtacatagtc gataccaccc tcacttaatt gagcttgatt
    50281 tttcttctcc atattatgta gttgtgggac aactttctga caatcagcaa ttgtgtcaag
    50341 aacggatcaa tcctttattg gagttgctcg aaagggtctt ctcttattac ggacaggctt
    50401 tgctcactgt acatagacaa caaatcatta tcctagtcaa tcggatttcc agagcctcat
    50461 tgctatcatt gcttgataaa atccagacaa agtttaataa aatgtatcag ttacagctaa
    50521 actttggaat tgggtcgctt tgttatacag agcaagagac accgcaatct ttccttcatg
    50581 ccaaacaagt ttgcgaatgg atagctttcc atcaatctgt gaacgagatc cgcttttttg
    50641 aagatttaga cctcgggatc gttttaccag caatcccgtc agatcaacga acattatatg
    50701 taaaacgtat tttgaaaagc ctgacagaag aagaagtaca tttgttcaag aagactttgg
    50761 catgcttcag taaaaataac ggaagcatca aaaattgctc agaagaatta tttattcata
    50821 aaaacacctt gcaatatcga ttgaacaagt tccattctct cactggttat acccctagaa
    50881 actatgacga ttatcatatt ctaaagctgg cttttttgtt ggtacaaaca tgacaactac
    50941 aaaaaaacca ggcgaacata tgattgttcg tctggttttt aattattaat gacttagcgt
    51001 ttttactaga aaaactactt ccgctttttc ccgccaaaag catctttaaa cttatcgaag
    51061 aaaccgtctt cttgctgttc ttcaactttg atgccgccag cttcagcgaa tgcacgtaat
    51121 gcttctcttt gttgttcatt tagatttttc ggtgtgatca gttttacttt gacatgttgg
    51181 tcgcctgttg caccaccacg taacttcgga gcgccttttc cacgtaaacg gaagttcgta
    51241 cctgtctgtg ttccagcagg gatcttcaat ttcacatctc catggacagt tggtacttgg
    51301 acttcatccc ccaaagctgc ttgtacaaaa cttaaaggca attcatagta aatttcagaa
    51361 ccttcacgat caaagatatc actttcttct acacggaaga ccacatacaa atcaccaaat
    51421 ggtccgccgt tttctccagc ttctccttga ccagctaaac gcatttgttg tccttcttct
    51481 acaccagctg gtacattcac tttaactgaa tgtgctttct tctcatgtcc tgagccatga
    51541 caggttggac aaggttcttt gatttctttc cctgtcccat gacaaacatc acaagtttga
    51601 cggctcatca ctcgtccaag tggtgtttgg cgttctacat taatcgtacc tgcaccatga
    51661 catttatgac aagtagttgg ttgtgtgcct ggttttgcac cgttcccacc acaagtatga
    51721 cagatttctt cccgattata cttgatttct ttttctacac caaaaatcgc ttcttcaaaa
    51781 gacaagtcga ccgtatattg caaatcagca ccttgacgag gcgcatttgg atcgactgac
    51841 cgaccgcctc ctccaaagaa agagtcgaag atatcttcaa aaccaccgaa gccgccacca
    51901 gagaagccgc cgaatccacc aaatccgcca ccagctccac cagcaccgta atttggatct
    51961 gtgcctgcat gcccgtattg gtcatatgca gcgcgttttt gcgggtcact taaaatctca
    52021 tatgcttctg atacttcttt gaatttttct tccgcatcag gttctttatt gatgtcagga
    52081 tggtattttt tcgaaagctt acgataagct ttctttattt catcttctga tgctcctttt
    52141 gagagcccta agacttcata ataatcacgt tttgttgcca taggctttcc tcctattggt
    52201 tctcatcatt ttcacgtcgc ttgttatcat atcatatttt gtttgaaaca aaaaccgata
    52261 cttcaaacta tttttcaaaa gaaaaagcca aagtagcaac tttggccttc tctcgaaatt
    52321 cagtgaactg attatttatc gtcgccatcg acttcttcaa aatcagcatc aacgacatca
    52381 tctgctccgc cttgagctgc ttctgggttt tcttgagctt gttgttgtgc cgcttgttcg
    52441 tatagtttaa cagtcaagtt ttgaacgatt tcgttcaatg catcgcgttt agttttcatt
    52501 tcttcgatgt tgtttgcttc aacagcggct ttcaattcat cgcgagctgt ttctgctttt
    52561 ttcacttctt cttcgtccac tttgccttct aattctttca atgttttgtc cacagagaat
    52621 agcaatgcat ctacatcatt acgtaggtca acttcctctt tacgagcttt atctgcttct
    52681 gcatttgctt ctgcatcttt taccatacgt tcgatttctt cgtctgttag acctgaagaa
    52741 gatttgatcg tgattttttg ttctttttgt gtacctagat ctttcgcaga tacatttaca
    52801 atcccgtttt tatcaatatc gaatgttact tcgatttgtg gaataccacg aggagctgct
    52861 ggaatatctg tcaattggaa tcttcctaga gttttgttgt cagcagccat tgggcgttca
    52921 ccttgtaata catggatgtc tactgctggt tgattatctg ccgcagttga gaatacttgt
    52981 gatttacttg ttggaatcgt tgtattgcgg tcaatcaatt tagtgaacac tccacccatt
    53041 gtttcgatac ctaatgacaa tggtgtaacg tcaagtaaaa caacatcttt cacatcacca
    53101 gtgatcacgc caccttggat agcagcaccc atagcaacta cttcatcagg gttaactgat
    53161 ttgtttggtt cttttcctgt ttctttacgt actgcttcta caactgcagg gatacgagta
    53221 gatccaccga ctaaaataac ttcgtcgatt tctgattgtg ataaacctgc atcttttagc
    53281 gcttgacgta ctggtacttt tgtacgttct actaagtcag ctgttaattc atcaaatttt
    53341 gcacgtgtca atgtcatttc caaatgcaat ggtccagatt ctcctgctgt gataaatggc
    53401 aagctgattt gtgtgcttga tacgccagat aaatcttttt tcgctttttc agcagcgtct
    53461 ttcaagcgtt gtaaagccat tttgtcttga gacaagtcaa tgctgttttc ttttttgaat
    53521 tctgctacca tgtagtcgat gattttgtta tcaaagtcgt ccccacctag atggttgtcg
    53581 ccagctgttg acaatacatc aaagacaccg tctcctagtt caaggataga tacgtcaaaa
    53641 gtaccgccac caaggtcgaa tactaagatt ttttcgtcgc gatctgtttt atctaaacca
    53701 taggcaagag cagctgcagt tggttcattg acgatacgtt ctacttctag accagcgatc
    53761 ttaccagcat cttttgttgc ttgacgttgt gcatcattaa agtaagctgg cacagtgata
    53821 actgcttttt cgactttttc acctaaatag tcttctgcga atcctttgat atattgaagg
    53881 atcattgctg agatttcttg tggtgtatat gatttacctt ctacatctac tttgtaacct
    53941 gcttcaccga tatggcgttt gattgatgaa atcgtatttg ggtttgtcac agcttgacgt
    54001 tttgcaactt cccctacttg gatttctcca tttttgaatg atacaacaga aggtgttgta
    54061 cggtttcctt ctgggttagc gatgattttt gcttcgtttc cttccaatac tgctactgca
    54121 gagttagtcg tacctaagtc aataccgata attttactca taattaacgt ctccttcttt
    54181 aattgaaagt gtaagtttta tatccgcaca attattgtgc aacaatgacc atggttggtc
    54241 ttaacacgcg atcatgtaat ttgtagcctt cttgtagtac ttctacaatc gtatcggctg
    54301 gtgtatcttc agtcgctgga acagtttgta ctgcttgatg aagattagga tcaaaggctt
    54361 ctcctttagc agggattttt tcaattcctt cttcttccag tgcgttacgc aaactttcca
    54421 agaccatttc cacgcctttt ttcaaacctg ccccttgatc atctgacact tctgtggcta
    54481 atgcacgttc caggttgtca attgatggaa gtaatttttt ggctaaatct tgtgaacggt
    54541 atttttgtaa ttgctcacgc tcattttttc ctcgatttgc catatttgcg atttcagcac
    54601 gagcccgcaa gtatttatct tccatttctt ctaactcagc ttttaatttc gctgtttcga
    54661 attcttccgc ttcagcttct gaaatacccg aatcttctgc agcttcgaca tcgatttccg
    54721 gttctggctg agcatctgtc atttctttat ctagttcttc ttgattttct ttcacgatac
    54781 agtcttcctt tcattattca gtcagctgtt tgattgctct tactaagaaa gagagaacga
    54841 tcagctgcaa atagcttcgt tattcacatt acgagtttga caagtcaagc gaacggtagt
    54901 aatcagcaag tttagctgct agttctcttc gataaacatc gactagaccg aacatccgag
    54961 aataaggcat actagtaggc cctaacaagg ctattgtacc tcttccatga ccatctatct
    55021 cgtaacttgc ttgaatcata ctcatattct gcaataaatc attgcctaat tcagcaccaa
    55081 tcttgatatg aatattgcta tccatcggag tgatcatttg tgtaagtccg tctgagtctt
    55141 tcataaaaga aaacatcgat ttgaactgat caagatcttg acggggctca taatccaaga
    55201 gattcatttg tccactgaca taaaccttat cttcaaaaac atgaccaaga acggtgtcaa
    55261 ataactgaga catcccttct gtcgtttgga aatatttatg aagaatcatc ggaatctccg
    55321 tacgaagttt atggtacacc gtcatcagag gatctccgac tagacggtcg tttacaatct
    55381 gtaccatttt ttctagttcc tgacttccca tatattcggg aagagtgaac acttggcttt
    55441 ctacattccc catatctgtt acgacgatag caataatctg tcgattattc aagggtacga
    55501 tacgaaagcc agtcagtcgg cggtctttta tttcaggtcc caatgaaaaa gtcgtatagc
    55561 ttgtcagctc agataatatc tcagcagatt gcttaataat ctcattgatt tcatgaaatt
    55621 ctctgcctag agactgacga atcagcagca aatcatcttc tgctacgcga gcaggtttta
    55681 acaaatgatc cacgtaataa cgatagccta aagcagatgg aatccgccca gaagaagagt
    55741 gagtcttcaa cagcaatcct tcatcttcta atgctttcat atcattgcga atcgttgctg
    55801 agctggcctt gactccctca gacatcaatg ttttggaacc aacgggcacg ccactactcg
    55861 tatagtgttg gatgatcaga cgtaaaatgt cgttttgtcg ctttgttaac atcttcctca
    55921 cctctcatta gcactcatat attctaagtg ctaatccact tataaatata gcaagaagcc
    55981 cttctcctgt caagagaaag actccatttt ttagcactct aaacacaaga gtgctaattc
    56041 taaataattg atgtaaatcc agttatatca acgtttcaat agtcctttat tgtatttttg
    56101 aacttttttt atttaaattc agataaaaaa caaatattct ttaaactatt tttcaaacaa
    56161 aaagcgctca aacacattgt tccccaaaaa ggtccctctt ggtgtcaaat aaacacggtc
    56221 ttcttcatta acaagtaacc cttcttgctc taattccctt agcacatcac cgtacaccga
    56281 ttcaattgtt ttttgatagc gatcatagaa atgtttttta gtaatccctg ttttttttct
    56341 tagtcctaag aacatttctt cttctatttg attttttcgt gtcaattttt cttcttccaa
    56401 taccgggcgt tcatttgctc gtaatgggcg taaatagtgt tggattggtc ctttgttgcg
    56461 gtaacgaata tctccaagat aaccgctagc accagctcca aacccaaaat agtgggcatt
    56521 gttccagtac atgaggttat gttgagattc atgtccggag agcccaaagt tacttatttc
    56581 atattggtga cgtccatgct tttccattgc ttcaatcgtc tcttcaaaca ttctggtttc
    56641 cgtttcctga tcaggcagtt cgagtcttcc ttgtcgtacc cagttcatga acattgtttt
    56701 gttttcgagg atcaatgagt acaaagaata gtgaggcaga tccaaagcca aagctttttc
    56761 caaagtatcc agatatcctt ctagtgtttg tcccggtaat gcataaatca aatcgatgct
    56821 tacattggta aaattttctg cttctaaaaa ttgcatagtt tgatacacat cttctgcggt
    56881 gtgtttacgt ccaatttttt tcaataagcg attatcaaat gtctgcactc ccatggataa
    56941 acgattgacg ccatagtttt tcattacttg aagtttttca cgggtcaaat cacctggatt
    57001 cgcttctaca gtaaactcat taccattttg aaaaggcagg atctctctag cacctgataa
    57061 cagtcgatca agttgtttag cagataaaga agttggtgtc ccgcccccta cgtaaagtgt
    57121 ttctaaattc gctgtcggat gactttctag cattattttc atttcattca gcagcatttc
    57181 cacatactca tctactggct gcccttctaa aaaaacttta ttaaaatcac agtaatagca
    57241 gatatgctcg caaaatggga tatgaatgta cgcagaaacc ttgttttctg cgggatttat
    57301 tgtttctatc attgaaattc tttctcctta cgtcgaaaag tcgtgcctgt tttcgacctt
    57361 cttaaaatcg cgttcaagca ccaactcatt gaaataagcc gcatatttag aatcaaggaa
    57421 acctagctct aaaaatgctt gcttattgtc atcggagcta cacggtgctt ttacagcctc
    57481 tcgataaacg gtaatcgcaa agctgacctt cggcattaag tcaaaatctg caaaaatatg
    57541 aaaagctatt ttcacagatt cctccttaag tgctcagacc acaacgcttt gcttacaacc
    57601 tctcatatac gcatactaaa cgtatttggc gaacaaatcc actaaaaaat ccaagaatcg
    57661 acttcttgga tgattttttc tttcattaaa ctggttacct agttatatat ctctagggtt
    57721 gttttcatgt ctgagtgccc gatatgattt atttttcgtt tctataatta ctttttgcct
    57781 tccagtttct tttaatattg tactcaagca agtgggaatt ggttcttttg tcatccatgt
    57841 atgcaaaatg ttataatgct ggtaaacaaa aatgattacc tgtcattttt atttagttcg
    57901 tatttaatta agttgactat ctgtatactc tgtctaaaac ttaagaattg ttgttttcgc
    57961 tgtcgctacc caattttaat gaatgtctgt aggttaaaac tgttgtcctt gttatagata
    58021 gtaaaggaga gcttgaaaat gaaaactgcg attacgtttc tattagagga atatgccgat
    58081 tgggaaggtg cttatattac tagcacacta aaccaaaatg agaaatggca aaacaaaact
    58141 gcttctatcc aatcagaggt cacttccatt ggaggattaa aaacaaaaat cgattactta
    58201 atcgaacaaa tacctgaaaa agttgacctt tttattatga tcggtggcaa ttcatgggac
    58261 ataaaaaatc atcatttata tcaaataatc gataaattgt taaaaacaga cgtaccagta
    58321 gctgctattt gtggggcagt tgattattta gctcagagcg gattattgca aggttacaaa
    58381 cacaccggaa atgcgcaatt tccttggtta gaatcggaaa attatcagaa taaagaagat
    58441 tttatagaac aacaagctgt gaaagatcgt aatttgatta ctgcgaatgg aacagctcct
    58501 atagaattca cagacttgat tcttcaagca gtccattttg aaacagaaga aataagagaa
    58561 aaaacgattc gtctatacaa acttggattc tatgattact ataaaaagta cggagatcct
    58621 ttctcctaat cattctcttc aattaaatac tccttatcaa tagtgtgaca agtaatttta
    58681 ctgatgatta tttgtcacac tttttctgac atttatcaaa gaagatacac tctatttata
    58741 ttcatagaca aggttttacg gattcaaaaa ttcaggatta tgctatactg gtattaaaaa
    58801 aataatgagg tattttatat gaaaaagtta ggttttattt tattgttggt ctctttattc
    58861 cttgtaggat gtacgtctcc tagtaaagaa aatagtgatc catctgcgac cacagacaaa
    58921 agttcaatca gacaaaccag ttcagctgaa aaatcaagta ctcagaaatc agcttctact
    58981 gaaacgaata catcttcaac aagcagtaaa gtctcagagc ccaatacttc ttctacatct
    59041 agtagtacag ttgagacaaa tatttcttct tcaacaatag acacaacctc ctcacagtct
    59101 tctcagtcaa tagatccgtt agcaggatat tctgatctac aaattgagta cgcacgtgtt
    59161 tggctagcta ttagaggtaa tacttttaga gatacatcgg gtgatttcga attacatgtt
    59221 attcattatc ctgcaggaac acctatcgcc ccttatgatg cagggagtgc agtctatccg
    59281 aaagatgtgg ttatgctcac tgggaaatac agttaccagg gagttttagt gtattcaagt
    59341 aaccatgacg ggacaatcac tagttatcca gttccttcac attggcaaat gcctgcagat
    59401 caaacatctt atccagcgtt cattagagaa acaactcaag aaatcattga taatgcatct
    59461 gtagtagcta ttcctacagg aaatcccaat gacgtgaaac agttaatcga tgtgacagtt
    59521 atagataatt agactttcta atatgttata caaaaagaag ctgacagcat tttgtcagct
    59581 tctttcactt tcttttctat ttagatttat tggtctttga tagactccaa ggcaggaaaa
    59641 aattttttaa ataaacgttt gcaaaacagt cgcttttcta tcttctaccg ctacttctgc
    59701 ataggcacca ttaatcaatg tcagttgtgg cggtacatga ccacaatcaa tatcatacaa
    59761 gatcggtagt tttaattcct ttgacagatc ttcgtataca tccttcattt tataatctaa
    59821 caaatcctct gccgcacttc taccgaacat gatccccgag ctgccatcaa accagcctgc
    59881 cagtttcatc tgaacaagtg atcttcttaa atcaactgac gatagctcac agttttctag
    59941 aaaccacaag atcggctttc catcattata ctttctttta aaagattgga catctccata
    60001 aggagtaccg attaaatgcc tgatcgtatc aatacaacca cctaataatc gtcccttcat
    60061 ccttactgca tctccgctga ctgattgcca atttgttggt tcagtgagat ggaaaacaga
    60121 agatgatgaa tgctcatggg gccacacttt ttgatacttt tcagaagatt gctgtagaat
    60181 cgattctcct tctcttgttt tcagtacact ttcccacatt gctgtcgttt catccaagta
    60241 ctctcctctt aaatcaataa ggttagttcc atgtgcagtg gctatccctg tttttaatgt
    60301 gacagcaagt agcaacgtac taatatctga ataacctact atccattttg gttgtagagc
    60361 atcaaaatcg acaaaatcga gaatctcaat caataattct cctccccaag tcggaaagat
    60421 catttggata ttttcatctt gcatcatttg attgaattca tctgctcgtt ttcttgctgg
    60481 acctgatttt tccttatctt gcgtccaaag cgtctttcca gtaactactt ggaaagattt
    60541 ttcttccatt ctctttaaag ctgattcgag taacgaatgg tgttcctctg atacgcctga
    60601 ggatggtgca gtaaccccaa tcgttgcatt tctttctaat aatggataac ttatcatgtt
    60661 gcttcacctc caagtatgca ctattttact tggttaattg tttttttcgt ttgccggcat
    60721 caaaaatatc ggcatctcaa gtagctggat gattttgttt aagtcaaccg tttggatgac
    60781 catcgtttga tctggtctac ctggtgcaaa aacaagtttt tcatttgata agagctcttc
    60841 atcaataata atcggaatct gtttttcata accaaacgga gaaacagcgc cctgcttttg
    60901 tcccgtttgt tcttccatgc gttctgatga aacaatagaa agccttttac cgacgatctt
    60961 ccctaatgct ttgaaatccg tttgtttcgt agtaaaagtc agatatacgt agttattatc
    61021 ttttttatct tttaagaata agcttttggt ctctgtacct gtaaatcctt gttctttctt
    61081 tattaccaaa gcatcttcat ttgtataaat ggctcgatga tgatacaact caaaatatat
    61141 attttcgtgt aagaatttct ttgccaagtc aatcattttt atgtctcttt tctattttat
    61201 tatttgagac atcttatcat ataaatatag cggttacaac attacttgtg ttttgttcgt
    61261 tttttataca taactattgt ttttctggta aaataaatca aaccacttaa tggaggcgtt
    61321 ttagaatgga aaaatttcag ccgatcatca atcaaatcaa agaaaaagaa catcaacaaa
    61381 agatcaaaga cctttttgct aagataacag aaacgtatcc ccagctagac acaactgtaa
    61441 aatggaacca acctatgttt actgaccatg gtacctttat tattgcattt agttttgcta
    61501 aaaatcattt ttctatcgca ccggaaaaag cagcgattcg tgcccttgaa aaaaatatcc
    61561 aagaagcagg ctacgtatat acggataacg tcatcaaagt tccttggaaa agtgtaatca
    61621 actgggaatt gattgaacaa ttgatttcat ttaatattga agataaaaaa ggtcatgata
    61681 aattttggcg ataaagcttt atacgaataa accttttact ggcgaggaaa ctattcatca
    61741 ccttatacag gttttgttca atcctatcct ttttatcatc cctggttaaa cacttaattg
    61801 acaaagtatc tgctattttt ataaggagtc tttcttgtgc tgaaaaaaat cactgattga
    61861 atggctttga attttctact tagtaaaatt attttttcag caattttcct gcaaaacttt
    61921 tgaataagga aaaaatacga gaaaatatca gtgatctttc ataatactgc ccattatttt
    61981 caggtatatt taaatataat atcactttag gagagaacga atttctttag agaaataaaa
    62041 gttagaattt tctgacttga tttttacaat gaccttaatt aaaatcgttc tttctacatt
    62101 tcgtgattaa gcaaatatca actaagtcag tagaaccatt cacataggag ggtgaacatt
    62161 gaaagatttt tactcagtaa atgaattagc cgaacaatta ggtgttacta cacgttctat
    62221 cagaaattat cttcatgaag gaaaactaaa aggaacaaag gttggcgggc aatggaaatt
    62281 ttctgaacgt aatctttttg agttcctata cggagatcaa gcagaggaag cagcaaaaga
    62341 aatgcagcga ttcatgctaa atgcaccaat cacgatgcgt ttcaaccttc aatatcgtga
    62401 ttttacagca atcaatcaat tccgagaaca attagtccag taccataacg atgtttacgc
    62461 aaataaaaaa gaccgtcttt tacaatacga tctttataaa gacaatcatg cggagatact
    62521 aatcggtggt aacttcaatt atgtcgtaaa ctttagtcaa tggatcaatg aaaaattatt
    62581 gatccagaca gatatttccc ttgtatctta aacaattaaa aagcgctaga aattccagag
    62641 atgttggaaa ttctagcgct atttttttat aagtacttac tgtttggttc aaacaaatat
    62701 ttttttaata aatgaaattt taccatcttt atcctcaaat aaagaccgtg accatgcttc
    62761 ctactacgat cagcaataat ccgataatcg ttaatttttt ttcttttggt gtcttatttt
    62821 catgcaggat gtacataccg cctaatgtag agataactac gtttagctgt gtaatgatat
    62881 atgcagtagc aaccccattt tcatttgctg aaaaaatata agccaatgct gacacactaa
    62941 agatggctcc aacgatcgtt gctttccaac tcttgtcttc agaaaatgcg gttggtttac
    63001 ggaaaatcac ataaatcact gcccctaaaa agacaccgat catttgcgga aagaaaatgg
    63061 aaagtccgct tgcatcaact agtttaggca atgcactgta tacccaataa ccaatacttg
    63121 ttgatgctaa tagactaatt ccttttgtga taccgccttt ttttccagga tcatcactga
    63181 ttgccgttaa agcagaacca aatacaagaa gaatgattgc tgctgctcca atgattttcc
    63241 ccatacttcc agaccattct ccaaaagcga agacaccaat caacgaggtt ccgactaact
    63301 gtaatgcagt cgaaattggc atcgttttag aaacaccaat caagttgaaa gatgtatact
    63361 gtcctgtttg tccaataacc caaaatgcac cagaaagtaa actaatcaaa aatgtagtca
    63421 ctgaaatacc agctggagaa gcgaataatt gaacgagtaa gccgacaagc accgctccaa
    63481 taccagttcc taatatctca tttgttggtc tgccaccaat ctttttcaaa atcagtggct
    63541 ggatccccca gccaactgcc gggatcaatg caatcaataa acccattttt attcaccctt
    63601 atccttttcc accttggaaa gaaggatata aagtcatccc accatctgca aatagtgtaa
    63661 tacctgtaac ataactggat tcgtctgaag ccaaccatgc agctgtcgcc gctatttctt
    63721 ttggttcacc tacgcgtcct agtgggatca tactttccaa gagttctttt tgttcaggat
    63781 catcaaattt tgccgcatta ataggtgtac ggatagcacc agggcctata ctattgattc
    63841 tgattccctt cggtgcatac tccattgcta ccgtttcggt aaataatttt accccgcctt
    63901 ttgaagcagc gtaatgagca aacgttggcc atgggatctg ttcatgaaca gaagacatat
    63961 tgatgatatt tcctttttta ttattctctg taaagtaatt taaagccgct ttcgttccga
    64021 taaaaacgcc agtcaaattg acttttaaca ctctttccca atcttcaagg ctaagttcat
    64081 gggttggatg ctgattttcc atcccagcat tattaaccca aacgtccagt gtcccaaaat
    64141 tttctaaagc cgtatcaagt aaacgctgta ttccttcttc agaactgaca tctgcttgta
    64201 cagagactgc ttttccgcct gcctcttcga ttgctttgac tgctttttct gctccttctt
    64261 tatccgagtt atagttgaca actacattca ttttttcttt cccgaatcgt tgagcaatcg
    64321 ctgttccaat cccctttgag ccaccagtta ctactgcgac tttgttttct aattccttgt
    64381 acatagtacc cactcctttt tcatacctaa acctgttatt acggataact tttatttccg
    64441 ccttaaagtg agtgtacacc aagatatata gtctaaagca aatgatacgc tctagcaatc
    64501 gttttcatga attgctagtg tccttttatt tctataaaga aagaggttgt gacagaagtg
    64561 gtcagcttca agaaatttcg gcttatttcc gaagaagcta cttctgaaaa accatttatt
    64621 tggaaaaaaa ggctgtgaca agacttttgt cacagcccct ttcctgggct tatttatcac
    64681 ccattttatt gtaattgcta gttatacata aacaagagat tttatgcata atgttttatt
    64741 gctgagaaaa atattcagct gttgcttgtt catcctcctt gagttgttca atcaattcct
    64801 ctacactaga aaatttcact tgatctctta aaaattgatt ccagcgtacc gcgacatgtt
    64861 caccatagat atcttgatta aagtccaaaa tatacaactc tacagtcagc tcccgtcctt
    64921 caccgaatgt atcattatgt ccaattgaac ccatggctgg ataccatgtt tccccaattt
    64981 ttatttccga cacataaaca ccttctttag gcaaatgaac cgtgctcttt actttgacat
    65041 ttgctgtagg gaatcctagt agtctgcctc gtgcatcgcc atggacaact accccttcta
    65101 cctcatatgt gcaacctaat agttttgctg cttcttttac ttgtccgctg tctagtaatc
    65161 cacgaatacg ggtagagctg attttttcac cttgttcttc ttctttagaa actgtgacga
    65221 ttttgaatct tcctttggca tattcaggaa aatgagcgac atctgcaatg tcttttggtc
    65281 catacgtata atcaaaaccg gaaacagcat attttgcatg taaccctacg atgtattgat
    65341 caacaaattc ctgcggtgct aaatgagcaa aagaagaagt aaaatcaact tcatataaat
    65401 aatctatacc caaagcggcc attttttctt ctttttgctt aaggctagtc aaatatttca
    65461 cgctgctagg atcgatcttt ttaaagacaa tagatggatg ctgattgaaa gtcatcaatg
    65521 ctaatttcaa tccttctttt tgtgcaattt ccatacctgt ctttatgact ttctggtgtc
    65581 cgatatgcac gccgtcgaaa aatcccagca ctaaaacgac atcgtcttct ggaatttgtt
    65641 ctgattggta aggatgtctg atcttgatga tattcattcg ttattcctca tttctcaata
    65701 ctttactagg ttttaatttg tttttttctt tcgggtttgg ctgataaata ctgacaactt
    65761 ttcctttata aaacaaagca atttcttctg acggcatttc tgggagcgca aatacagtat
    65821 aatcaagtct cataccgttt tttactttct gccatacttc atcagtaata tctactcgtt
    65881 tgaaccgttc cactcctttt tctattggca gcaaacaatc atcgattgtc ccatttttca
    65941 cagcttgagc tacttcttct aatgtcagag catccttctg ggacataccg gcacttgctg
    66001 ttcgggtcag atcagacatg tgcgcagggt aaccaagttt cttgcctgta tctacagcta
    66061 atgtgcggac ataggttcct ttcccgcatt ctacttcgaa gcgccaagaa atggttcctg
    66121 tcacttcgtc tcttgtcaat tcacttgtcc ggataaaacg gtaaatctga gcctttctaa
    66181 caggacgctc cactgtttca ttattgcggg catattcata taaccgctta ccgttgactt
    66241 ttaccgctga gtacattggt ggtatctggg tgatctcacc aataaatgaa gccatcactt
    66301 catctatttt tttttcagat aaagacatat ctactggttt tgtttctacc cgttctccgg
    66361 atcgatcttc cgtcgttgta ctgaaaccta gagttatctc gcctacatag attttcccag
    66421 aatctgtcaa atattcgata acttttgtgg cttttccaat acaaatgggc aacacaccgt
    66481 ctacgtctgg gtcaagcgta cccccatgtc cgattttttt cgtatgtaag atttttctta
    66541 atttgaatac gcaatcatga cttgtcattc cgcgttcttt ccataaaggt aataacccgt
    66601 ccatgtcttt tctccatttc atttttgatt taactgaatt attataacac attgcatcaa
    66661 ttactgacga atttgacatc ataatgaacg gtttttattt ttcggcaata aaaacgtaac
    66721 aaaattcatg ctcacgtaaa tagaaatcat gttatgcttt tttaaaggag ggaatagaat
    66781 ggaagatttt ttctttgcac catttgattg gatttatggg tggcttacag gtaaatagtt
    66841 tggttttcac ttcccaaaaa cgaaaaaaaa gactggccat tcttccagtc ttttttccgt
    66901 tttttttatt tattttttca gtttcttaat caatgtaaaa aattctattt tgcgggatcg
    66961 attttatcat tttattggtc aagatttttc catttccaat ccaatacttc tggcagatca
    67021 ataccatttt cacgaatata gttttgatgt tcttgtaatt tctgatccat ttttttcgca
    67081 aaatcttctg cttgacttcc tttgattttt aaagctgcgt cttttgccaa atgataacga
    67141 tcaagttcat ttactacacg catgtcaaat ggtgtcgtga tatctccatt ttctttgtag
    67201 ccatgaatca ttaaatgatg gttatgacga tcaaagaaaa tcgtgcggac caatgtttca
    67261 taaccgtgga aagcaaataa gatcggtttg tcttttgtaa aatattgatc aaattcttca
    67321 tcgctcaacc cacgcggatc ttgacttgga tgacgtaatt tcaataaatc tacgacattg
    67381 atgaaccgaa tttttagttt tgggaattct tccagcagca aagttacagc tgctaatgct
    67441 tctaagttag attccgttcc tgcagcagca atgaccaatt caggttcctc ctcttttgct
    67501 gtcgaagccc aatcaatgat tttcaagcct tcattcacta agacggctgc ttcttctgct
    67561 gagtaaaatt gagcacgcgg atgtttggaa gagatgatca aattgatttt ttctgacgag
    67621 cggaatgctt tatccatgac tgcgagcaat gtatttgcat ccgcaggcag atattcacgg
    67681 atgaactccg ccttcttttc tgccaaatgt gtcaatattc ctggatcttg gtggctatat
    67741 ccattgtgat cttgctggaa gactgttgag cttgcaatga gatttagcga aggataatca
    67801 tttcgccaag aaaggtcatg tgatttccgc atccatttga agtgctgagt caacatagag
    67861 tcaaccactc gcaagaatga ttcgtaactt gcaaaaaacc atgccgtcca gtcagaacgt
    67921 acccttctaa gaacccttca tcttggtgtt ccgataattg actgtcgatg acgcgaccag
    67981 atggcgaaag ccattcatca ttttctggtt cgattttttc catccattgg cgatttgtcg
    68041 ttttgaaaac ttgattcaat cggtttgatt ttgtttcatc tggtccaaat atacggaaat
    68101 tttctggatt tttctcaatg atctcgcgaa cgaatttacc aagttcggtc atatcttctg
    68161 ctttaacgga gcctggtttt tcaaattgca aagtatattt tttccaatct ggcataataa
    68221 gcggtcttgg atcgattcca ccattggtga taggattttt tgccattctt tggtcaccag
    68281 taggcgcgat ttctctgatt tcttctaaaa tacgtccttg tgcatcaaat aatttttctg
    68341 gttcatagga tttcagccaa cggagtaaag catctgcatg atccatatgt tcttgatcta
    68401 caggaatcgg tacttggtgt gctcggaagg ttccttcaat tggttccccg tcccattctt
    68461 ttggaccggt ccatcctttt ggtgtgcgta cgatcaatac tggccatttt ggcatcacga
    68521 catctgttgc tgtcttcagg cgagcttctt tttggatgga tttaattttc tcgattgctt
    68581 gatccatttt ttcagccata acaggattta atttttctga atcatttcct tcaataaaga
    68641 aaggttccca gccaagtccg ttaaagtaat ttgctaattc tccatctgat ttacgtgcca
    68701 agatcgttgg gttggctatt tttgcaccat ttaaatgaag gatcggtaaa acagctccat
    68761 ctatcactgg attgataaag acatttgaga accagcttcc agctaaagga ccggtttctg
    68821 cttcaccatc accaatcacg acagcagaga ttacttcagg attgtctaat acagctccga
    68881 ctgcatgtga aagagagtat ccaagctctc cgccttcatg gatagaacct ggtgtttctg
    68941 gtgctgcatg agaagcaatg cctccaggaa atgaaaatcg tttgaataat ttttgcattc
    69001 ctgtctcatc ttccgttact tctggataga tctctgtgta acttccatct aaataagcat
    69061 tcgataccat gacttgtccg ccgtgtcctg gcccttcaat ataaaacatg ttcaaatcat
    69121 atttattgat gactcggttc aaatggacat aaataaaatt ttggccagga atcgttcccc
    69181 aatgaccgat tggatgtttt ttgacatctt cgggtttcag tgtacgtctc agtaaggggt
    69241 tatctttaag ataaagttgc ccaacagaaa gataattagc agcacgccac caagccgtca
    69301 ttttatcaaa gtattcttta ctagaataat ccatacataa cactcctttt cattattact
    69361 cttattctag cgcagatact cccaattgaa acctaataag cacttctgtt catttgtttg
    69421 gattttatat ctagccaaat gaacaggtat aaaaaaccac gaaatttttc ctttcgctga
    69481 cgttttttac attgatccaa aaaacttgtc gttatcacaa tggctgttcc gcagttcatt
    69541 tcgctcctca tcatgcataa tttgctgaat gacgctgggc cagttaacac attgctggaa
    69601 aactggggct ggatcgagca attcctttcc tgattgatcc gttttatgta aaagtctctg
    69661 ttatctttgt caatatgtga attggtatcc cagctactat gctaatttct acagggatta
    69721 tccaaaattt ggatcgtgac caaatcgaag cggcgtaatc ggaaatatca ataacttcaa
    69781 cgtgattttt cttttaactg tcaacggacc gacaaactca aacttttatg gtgcaggttc
    69841 cactgatctt ctagttactt ggctatacct gactgtcact aaaatagatt acaatctagc
    69901 ttccgttatc ggtatcttga tctttatcta tatgcaaaaa tttatatact actagaaaaa
    69961 agaaagtcga attttttact tttctttttc tcttttttgg ttagctgaca cgccgcaaga
    70021 ctaaagtcat ggaactctta ggtaatacgt cttaatgaaa acaaaaaaat cccgcaaccc
    70081 ctgatttcac aggatttgcg ggagtttttg attagtcttt gttcaagtcg cgaagcaatt
    70141 catcgatatg gttgccatag acaactgatt catcaagttc aaagaacaat tcaggtgtct
    70201 tataaatact tagattgtgc cctaactctc gacgaatcaa tcctgatgct ttattcaatc
    70261 catcttgtgc tgttttctta tctgatgcta agtcagataa aatgctgtaa tagatcgttg
    70321 cttgctgtaa gtcccccgta actttcacat ctgtgatcgt tacgttctcc acacgagggt
    70381 cacggacctt tttgcgcaaa atatcattga cttcttttaa gatttcttga ccgactcggc
    70441 ggtcacggta gttagccata atgattggcc tccttttatc agtttttagt catttttgac
    70501 ttcttccatg ataaatcctt caattacgtc atctactttg atgtcattga atttttcaat
    70561 cattgcacca cattcataac ccattttgac ttctttcacg tcatctttga atcgtttcag
    70621 acttgcaagt tggccttcat agattacgat tccgtcacgg attacacgga caccgctatc
    70681 tctacgaata tatccttctg ttacataggc acctgcaatc gtaccaactt tagaaacttt
    70741 gaaggtttca cgaacgatca tttgaccggt gattttttct tcaaattcag ggtctagcat
    70801 ccctttcatc gcagtttcga tttcttcgat ggctttatag atgatacggt gaagacgaat
    70861 atcgacttct tcagtatcag cttgcacttt tgcctgcggt gtaggacgaa cgttgaaacc
    70921 gatgataata gcgttgctgg ctgctgctaa ggttacatca ctttcattga ttgctccgac
    70981 agctgaatgg acgattttta cacggacacc ttccacatca atcttcttca atgatgcagc
    71041 cagtgcttct gctgaacctt gtacatctgc tttgatgatt acgttaactt ctttcaattc
    71101 gccttctttc aggctttcaa ataagttatc caaagtcaca cggcttgtgg cagcacggtt
    71161 ttctaataat gcacgtttcg cgcgttcttc acccgctgca cgtgctgtct tttcgtcttc
    71221 gaagactacg aaacggtcac ctgcttgagg tacatcattc aagccagtga tttctactgg
    71281 cgttgcaggt cctgcttctt tatcgcgacg gccaagatcg tttgtcatta cacggacacg
    71341 tccgtaagta ttaccgacaa cgattgggtc accaacatga agtgttcctt cttggacaag
    71401 taaggttgac acaggacctt tacctttatc aagacgtgct tcgatcactg ttccgattgc
    71461 gcgttgtgtt ggatctgctt ttaaatcttc tacttctgcg actaacagga tcatttccag
    71521 caattcttcg atgttttggc cgaatttcgc tgagatctca acaaagatcg tttctccacc
    71581 ccatgcttca ggaattaact catactcact taattcttgc ataacatgtt gagggtttgc
    71641 acctggttta tcaattttat ttacagcgac gatgattgga acgcctgcag ctttggcatg
    71701 gttgattgct tcaactgttt gtggcatgac gccatcatct gcagcaacaa ctaagatcgt
    71761 gatatctgtg atacttgctc cacgtgcacg catacttgta aaggccgcat gtcctggtgt
    71821 atccaagaaa gtgattggtt taccatcaat atcgatctgg taggcaccga tatgctgtgt
    71881 gattccgccg gcttcgccgc ttgttacacg tgaatggcgt aatgtatcca ataaagttgt
    71941 tttcccatgg tctacgtgtc ccataatcgt tacgactggc ggacgtgaga ctaatttatc
    72001 tggatcgact tcttctgcct cgaagaattt atcgatatca gcaatgtcaa cttggacttt
    72061 ttcttgtggt tccatgccat agtccgtcgc taacagttca atcgtatctt tatccagtgc
    72121 ttggttttga ttgaccatga caccaagcat aaataatttt ttaatgattt ctgctggctc
    72181 acgatgaatt tttttcgcaa tatctgctac gttcatacct tcagtatact ctaatacatc
    72241 tggcaattca cggaatttgc gtggtggtac agctggttta gttgattgtt gctgtttgcc
    72301 ttttttacct tttttattat aacgattacg gttattatta ttaaatttgc cgcgattgtt
    72361 attgtttggt ttgttgttat tgttagtacg gttttgattg ccgccttggc tcgttccttg
    72421 acgattttgg ctgctggtat ttcccgtatt attttggttt gttgttggtt tttttccttg
    72481 attcacttga ccgctccctt gaccgcgatc ttgataactg cggttatttt tatttttttg
    72541 ttgattgttc gttgtttctt ttttacgttg atcgttcggc tgttgattgg ctggttttct
    72601 gcttgcttgt tgtgcagctt gttgtttcgt gcttgggttt ttgaacgctt gttgcaattt
    72661 cttctcatca ttgctagtaa tcgcacccat atggtttttc acatcgatgc caagttgttg
    72721 tgctttttcc acgacgtctt tactagattt tttgagttct tttgctaatt catagattct
    72781 tttgttgccc atgcaatcac cttcctaacc ttcaattagc tccttggtct tcttcgcaaa
    72841 tccggcatcc attattccga ataccttgcg aggttttccg atcatctgcg tgatttctgc
    72901 ttcagaaaat agctcaaagc aaggaacttc ataatatgaa ctcttatctt ttatcttttt
    72961 tcttgtattc tcgcttgcat cggttgccac aaacaccaat tttgcttttt gtttgcggat
    73021 ttcagcaatg gtcagttctt cacccgtgat tagttttccc gcgcgcatcg ctagaccgat
    73081 gagattcatg gctttttgcc gattaactgt attcattttc caaataactc tttacgtgct
    73141 ttttggtgag tgacatagtc aagaagttct tgataaaact catctgttaa tgttgtttcg
    73201 agtactcgat cgagaatttt tttatcccaa gcttgttgta cttcttccgg ctcaagtgag
    73261 acatacgctc ctcgtccagg catttttcca gttggatcga tcgatacttc cccttctttt
    73321 gaacgggtga ttcggaccat ctctttttta ggtttcattt cacctgaaac cacggatttg
    73381 cgtaaaggaa ttttcctttg tttcatctct ttgcctcctt actaaagtta agcttctggt
    73441 ttttcttcga ccgtttcatt gttgaatgca attgtttcat attcatcgtc tgttaaatct
    73501 gactgaacga ttgcttcatc atgcagttct tctgtttctt tttgttgttc ttgattttca
    73561 taaaattccg tcatgtcaga ttctgatttg atatcgattt tatggttagt caatttagca
    73621 gctaaacgtg cgttttgtcc gcgtttaccg attgctagcg ataattggta gtctggaacg
    73681 acaactgtgc aggcctttgg atttgtctca tcgaagatca catccatgac ttgtgcagga
    73741 ttcaatgcat ttgcaatgaa tacagctgga tcttcattcc attcgacgat atccatgttt
    73801 tcgcctttta attcattgac gattgcttga actcgttgtc cctttggccc gacacatgta
    73861 ccgactgcat cgatatttgg atcatttgag cgaactgcca cttttgaacg atcgccagct
    73921 tcacgggcga tgctgacaat ttcaacgatt ccatcataga cttctggtac ttcttgctca
    73981 aataagcggc gcaataggtc tggatggctg cggctaacaa atacttgcgg acctttagac
    74041 gtattttcta ctcgggaaac ataaactttg attcgatcat gtggttgata aaattcattt
    74101 ggcatttgat cttgtttaga aagaactgcc tcaattttac caagattgac ataaatataa
    74161 cgtttatcct ggcgttcgac gattccttgc atgatgtctt tttcataagc actgaattcg
    74221 ttataaataa tcgttctttc tgcttcacgt acacgctgta aaataacttg tttagccgtt
    74281 tgcgcagcga tccgcccaaa atcttttggt gttacttcaa aacggatcgt atcaccgatc
    74341 tcatatgctg gattgattaa aagtgcatct ttcaatgaga cttccaactg tgaatccatc
    74401 acttcttccg ttacttcttt taccgcatag acatggatct ttcctttttt ctgatcaaat
    74461 tccacttcga cgttttgtgc ttggccatag tgacgtttgt atgcagaaac caatgctgct
    74521 tctaaagcat cgatcacgat ttcttttgag atcccttttt cagcttctaa agcgtctaac
    74581 gcatttaaca tttctttact cattttttct gattcctctc cgtgattaaa attggatagc
    74641 taagcgagct tttgcaatat tttttcggtc aaaagtcaat tctttttctc gtgtttttat
    74701 gcgtattttc aatgtaagct gttcagcatc aaatgattga agaaatcctt catattgttt
    74761 ttcgccatct actggttggt ataaggagac atggacataa tcaccaagtg ccttttcata
    74821 gtcgctttct tttttcaatg gccgctctgc tcccggggag gatacctcca ggaaataagc
    74881 ttgaggaatc ggatctggat ctgctgcatc aagtttttca ctcagtttct cactgacaaa
    74941 ggcgcattct tcgatatcga taccgccttc tttgtcaata aatactcgta agaaccagct
    75001 ttttccttct tttacaaatt cgacttcgac aagttcaaaa ttttgttcat ctaaaatcgg
    75061 tgtcaccatt tctgtgactg tttcaacgac gctactcaaa agtttcgcct ccttaaaaaa
    75121 ttaagtgcgt aattccatta aaaagagtga gcgaaaaatc cgctcactca cagttagtat
    75181 cattacctat aagaactata ccatactctg cttaaaatta caagcagaca ggaaaacaga
    75241 tgcttatagc atatcgaata acgataattg attttcatct ggtagatctt tcaatacgcc
    75301 attgtcgttc atatattcga tcaatgtttt tgaaacttta ccgcgggtgg caagatcttc
    75361 tttggataaa aatggaccgt cttttcttgc ttcaacgatt tgttttgcca cgttggttcc
    75421 caaacttggg acagctctaa atggtgcgat caacgtatca ccttcaataa caaagttaac
    75481 ggcatccgat ttatacaaat caatcattcc aaatttgaat cctcgttcca gcatttcatt
    75541 ggctaactcc agcactgtca gttgattctt ttcttttacg gaagcatcta atcctttgtc
    75601 cgtgatttct ttcattgctt gtttcacagc atcttttcct ttgcacatgg agactagatc
    75661 aaagtcgtct gcacgtacag aaaagtatgc acagtaatac aaaataggga aataaacctt
    75721 gaaataagcg acacgaagag ccatcaatac gtaagctgca gcatgggctt tcggaaacat
    75781 atatttgatt tttgaacaag aatcgatata ccagtcgggc acattatttt ctttcatcgc
    75841 cgatagatag gtttctcgca attcatcagg gatcttgttc cattgtcctt tacgaacagt
    75901 ttccatgatt ttaaatgcca tcccgctatc taatccagca tggatcaaat aaaccataat
    75961 atcatcacga cagccgatta cttccgccag tgtcgcatct cctcgtcgaa tcaattcttc
    76021 cgcatttcct aaccatacgt ctgtaccatg agatagtccg gaaatttgca gtagttctgc
    76081 aaaagttgta ggatgcgttt cttctagcat ccctcgaaca aaacgagtgc cgaattctgg
    76141 aatacctaat gtccctgttt tggaataaat ttgttcctga cttactccaa gtacttcagg
    76201 accggcaaat atccgcatca cttccgggtc atccgtaggg atcgtttgtg gatcgatccc
    76261 tgataaatct tgaagcatcc gaataacagt tgggtcatca tgccctagaa tatctaattt
    76321 caatacatta tcgtgaatcg agtgaaaatc aaaatgagtc gttttccatt ccgaattttg
    76381 atcgtctgct ggatattgga tcggcgtaaa atcatagaca tccatataat cgggaataac
    76441 gatgatcccc cctggatgct ggccggttgt ccgtttgact ccagtagcgc cttttgctaa
    76501 tctgtcgact tctgcacttc gaaactgcag attattgtcc ctttcgtatc cttttacata
    76561 gccatatgct gttttgtcgg cgactgtacc aatcgttccg gcacggtaaa catagtcttc
    76621 gccaaacaat actttcgtat agttatgggc ttctgcttga taatcacctg agaagttcaa
    76681 atcaatatcg ggcactttgt ctccatggaa tcctaaaaat gtctcaaatg gaatatcatg
    76741 accgtctttg tttaagcgtg caccacattt tggacattgt ttttctggca tgtcaaatcc
    76801 agaaccatac gtaccatctt caaaaaactc ggaatattgg cactctggac aataataatg
    76861 aggggctaac ggattaactt cagtgattcc tgtcatcgtc gcaacaaagc tagagccaac
    76921 agagccacgt gaacctacta gatagccatc ttcattactt ttatgcacta gtttttgggc
    76981 gatcagataa ataaccgaga agccattacc attaatagaa ttcaactctt tttttaatcg
    77041 tttttgaatg atctcaggta acggatctcc gtacatttgt tttgcttttg tgtaactcaa
    77101 ttctgatatt tcatcttctg aacctggaat cttcggtgta taaagttcat ctttgactgg
    77161 aatcacttct tcgcagatat ctgcgatttt attcgtattt tctactacga tctctttcgc
    77221 tgtttcttcc cctaaaaagt gaaatgcagt tagcatctca tcggttgttc ggaaatggac
    77281 atccggcaaa ctatgacgat tcaacggatt cgctccgccc atagaattga tcaaaatttt
    77341 tcggtaaatg gcatcttctt cgttcagata atgtacatta cctgttgcaa caacgatttt
    77401 atccaaactt tttccgattt ctaccaaatt ttggataatt tcttccaaat catgttcatt
    77461 ttttaccaat tcttgctcga tcaaaggcgc atagaccgct tttggcataa cttcaatata
    77521 atcgtagaat tttgctcggt ttcttgcctc ttctacccct ttttgcatca tggcttcgaa
    77581 tatttctccc ttatcacaag ctgagccgat caatagattt tcacgcatct ttttcaattg
    77641 ggagcgtggt attcgtggga cgcgttcgaa gtattcgaca ttcgacattg aaatcagttt
    77701 gaacaaatct ttcagtcctg cctgattttt tgctaaaatc gttacatgga aaggtcgagc
    77761 ccttttgtaa gaatctcctt ctccgatatg ctcatttagc tgatcatgat aaagcatgtt
    77821 atgattgtcc attgcctctt tcacaaagat ccatgctaag tgaccagttg cttcagcatc
    77881 atagattgct cggtgatgct gttccaagct gacaccaaat tttttagata acacacctaa
    77941 tccgaaacgt ttgaattgag gatacagata tctagctaat tccaacgtat caatgactgg
    78001 attggccgct tcaggaatac cataccttgc gtagctagta ttcaagaacc ccatatcaaa
    78061 agccgcgttg tgggctacca aaattgtatc ttttgaaaat tcaaggaaca tccgcaatac
    78121 ttcttcttcc gactttgatc ctcgaaccat tccatccgtg ataccagtca gatctaccgt
    78181 tgttcgtgac aaaggatgtc ctggatcgat aaattcatca aagctttcga tcacatttcc
    78241 tttatacatt ttgactgcgg ctagctcgat gatcgtgtca tatactgcag acaatcctgt
    78301 cgtttccacg tcaaatacga catatgtggc ttcactcaat gcttcatgtg catcattata
    78361 agcaattggg acaccatcat ctacgacatt cgcttccacg ccgtataaga ttttcacacc
    78421 tgcttttttt ccagcactat gtgcttccgg aaaggcttgc gcaccaccgt ggtctgtaat
    78481 ggcgatagct cggtgtcccc atttccctgc ttgtgccaca agatcagaga tgctgtttgt
    78541 tgcatccatc gtactcatat tgctatgaac atgaagctct actcgttttt ccccttcagg
    78601 agcataatct ttgcgaggtg tatgtttgac ttctatgata tcttgcgcat tcatgaccaa
    78661 atcacggaca aacgtatctt cttgaatact tcctcgtacc tttaaccagc taccgacact
    78721 gatcgcatca aatacttgtt catctttttc gccgttcgag aattttttga cgataaatga
    78781 tgaagtataa tctgtgattt tcaaagtcaa gatcttgcgt tttgaacgta gttctctgac
    78841 ttctttgtcg aatacgtacc cctcaagtgt gactcttcgt tcttcttcaa cgatactgat
    78901 cattggtgtc gttggttcat cggctggaat atttcgtcct agctggatgt ggatgggtcc
    78961 ttcaagagct ggcgattgct cttttctttc ctttttcttt tgttcgtgga caactagact
    79021 ttcagctgct tgcttcataa aggcttctgc ctgttcttgt ttgcgttctt caaaaagttt
    79081 caatactcgt tccgcttgct gctcatccac ttctggttcg atacgaaatt ttgggaatcc
    79141 gtaactgacg aacaactctt ctactaatgg caagtattgt tgcttcaaat aagaaatagc
    79201 tcctgtactg tcgattggca agatgacttt acgatctttt atcacaggta cctgcgtttt
    79261 cagtacttgc tgtgctagtg gtgtatcgca ttgctgattt tccaaagctt gggcccagta
    79321 atcttgcaag agctgttcat cgaatgtctg gtcatctgct aagatattca gtttgacttg
    79381 tgcaatatct ttaaaagcga tagtcagatg ctgagtcaat gaccgatata gcataatagg
    79441 caaaattttg gaaaaatgca gcgtaaattc ccataaacgc gatttacgat ggaccactac
    79501 actatccatt tcaccagcag taagcagtgg atgatttttt tctgcttcct ctagttggat
    79561 ttgttccaac agtttttcaa ataaatctcg tttttctgac aaagatatac gccctttctg
    79621 atgagaaaca atgcaattga tcgcatctta tcctcttctt tttcagtacc ttttagtata
    79681 ctcgtttttt ctgagtttta cattaaaaaa ttggaactgc gattcaaatc gcagttccaa
    79741 ttttaaaagc gaatcatcag attgtcaaaa acagctgatt cagctatttt tattttctgt
    79801 gttttaacgc ttattattcg ccttggttca agaggattgg taaagtattc accaattctt
    79861 ctttacgtac ttcaaccatt tcgccagttt tcttgatttt cacttctacg attccatcca
    79921 ctgctttttt accgacagtg attctgattg gacagccaat caaatcagaa tccgcgaatt
    79981 tcactcctgc gcgttcattt ctgtcatcaa ccagtacttc atagccagct tttgtcatcg
    80041 cttcttctag ttcattcgtc aggtttgttt ggtattcgtc ttttagattc atttggacga
    80101 tatgcaaatc aaatggcgca attccttttg gccagttgat tccttgttca tctgaatgtt
    80161 gttctacgat tgctgataat aaacgactta caccgatacc ataacagccc ataatcacaa
    80221 atttttctcg tccattttcg tctagtacag ttgctcccat agattcactg taacgagtgc
    80281 cgattttgaa gatatgtccg atttcgattc ctcgagtaaa ggcaagaaca ccattgttgt
    80341 ctggtgaagg atctccttct tgtacaaaac gaagatcttc ataagaaagt acagtgaaat
    80401 cgcgttctgg attcacattt ttatagtgga atcctgtttc gttcgctcca gtaatggcat
    80461 tcgctaaatc ttggacataa cggtctgcat atacttttac gtcatctgaa acaccgactg
    80521 gtccgacaga accaaactca gcacctagat atttttgtgc ttcttcttct gttgcttctt
    80581 ctaaaaagtc agcagataaa aagtttttca gttttacgtc attgacttca tggtctccgc
    80641 gtaccaaaac aaggacaggt tgttcatccg caatgaacaa tacagacttg atgatttttt
    80701 gaggttcaac agaaaagaaa tctgctactt cgtcaattga ttttacgtta ggtgtagcta
    80761 ctttctccaa ttcaagctgt gtttcatgcg atttttttga tacatagtag cttgtagcca
    80821 tctccaagtt tgcagcataa tcactttcag tcgaataaca gatcgtatcc tccccgattt
    80881 ctgagatcgc catgaattct tttgagtctt tcccgcccat tgcgccaccg tctccgataa
    80941 tcgagcgaaa ttctaagcca caacgcttga atacttcggt gtaggctttt tcgtaatctt
    81001 tatatgtctc gtccaaactt tcttccgttg catggaaaga atacgcatct ttcatgataa
    81061 actctcttcc gcgaagcaaa ccgaagcgag gtcgtttttc gtcacgatat ttaggttgga
    81121 tttgataaag atttaaaggt aatttcttat atgaattgat ttcattacgc atcaaatcag
    81181 taaaagtttc ttcgtgagtt ggtccaagga tcatttttcg atcattgcgg tctttgaaac
    81241 gatacaagtt tggtccatat gtttcgtaac gcccggattc ttcccaaagt tctgctggca
    81301 agatggcagg catcagcatt tctaccgctc cgattttttc aaattcttcc cgcataatgc
    81361 gtttcagttt ttccaataca cgatttgcta atggcagata tgaataaata cccgctgata
    81421 cttggcggat atatccagct cttagcaaga tttgatggct taatacttct gcatcatttg
    81481 gaacttcgcg taatgttgga atcaacattt ttgattgtct cattctatat actcctttat
    81541 ttcctcaaaa tagttatcgt ttgttattat accctatttg tcaacttttt ctagaaaaag
    81601 aatcgttgaa tatcgttcca tgtaactagc accatcaaca acattaaaaa tccaaagcca
    81661 gctaatgtca atattccttc tttttcttga cttaatggtt tcccgcgaat cccttcaaaa
    81721 atattcaaga ctaatttccc gccatctaag gcaggaatcg gaagcagatt gacgattccg
    81781 agattcattg aaagaagcgc catcaaacta ataacagttg ttacaccttg atttgctgct
    81841 tctgaagaca attggtacat catgacaggt ccgcctaatt tatctaaact gaaacctgta
    81901 aatagtgatc ctaaggcttt gaaaatttcc aatgaaccgc tgaaagcttg acgcgtccct
    81961 ccaatgatct tatccataaa acctgtattc attggggctt ttataccaag ttggccaact
    82021 ttttcgccat ttgactctac agatttcggt gtcacgtcga cagattgcac ctgaccttct
    82081 cgttcgatct taaagtctaa tgttttatcc ggatttttcg taatgactgt tgtcagatca
    82141 ttccatgaat ggatttcttt tccgtccaca ctgactacct catcattttc ttttaagcct
    82201 gcttctgccg cagctccatt aggcatgatc tctcctacgc gattagtgtt cgtcacttga
    82261 acaccacctt gcataaatgc cagaatgatg aataacagga ttgccaaaat aaagttattc
    82321 atgggtccag caaagttggt cagcatacgc tgccacaatt tagccgattg gaactgtacg
    82381 tcttttggcg caattctgat ttctgttccg tcgttttcaa taatcgtcgc atcgtgatca
    82441 acagggtagg ttactacttc tgtttcgtct ccattcacat aaccagtgat agtcagctca
    82501 tcttctaaat cataacggct caattccatc gggatagcat ttgtcaattg gattttctta
    82561 cttaaattta tcttctctac gatgccgtca gaatttagta aaagagaaag aggcattcct
    82621 ggtgccattt ctgtttcatc atccccattg cctgccattc gaacataacc gccaataggt
    82681 aataggcgaa gcgtatatgt tgtcccgtct tttgcttgat gcccataaat tttcggaccc
    82741 ataccgatag caaattcgcg aacgaggatt cctgatcgtt tcgcaaagaa gaaatgacca
    82801 aactcatgaa caatcactaa tataccaaaa acgatgataa atgtcagaat cgttttcata
    82861 gcttttttct cctttacttg ttttttgtgt tttttataaa acaacgataa aacactataa
    82921 ttttaccata gtataccaaa gacaccaata gtatcaatat aatgaaaaat aaaaacctgc
    82981 gtcttttatg aaattcacaa agaaacgcag gtatacttac taaataatgc caaataaatg
    83041 catgatagga aatacaaaca gcaaactgtc gaaacggtct aagattccac catggcctgg
    83101 taagatattt cccgagtctt tcacatcata atgacgtttg attgcagatt cgaccaaatc
    83161 accaaattgt ccgactgctg aaaaaataat cgtcatcaga agcatgacaa acataccatg
    83221 attaaatagt tcttttgctg ggtatagcaa taaataaaga aatgcgacta caacagcact
    83281 accaatacca ccgagcgcac cttcaatcgt tttgttgggc gaaatatcag gacttaactt
    83341 atgctgacca taacgtcgac caaccatata tgctccgata tcagttgccc aaacaataaa
    83401 tagaccaaat atcaaaacag ccaagctttc tgttcgtgca ttgacaaaat tctggaaacc
    83461 tattcccaca tacaagctga caagcacagg aaaacctgct tcatcaatcg tatacgtatt
    83521 tttagaaata actgatgttc ctaaaagaat cataactata agataaaata acataaatgt
    83581 acttacattc tctggaagaa agaaaaacca tctttctttt ggcaaaacaa gtaacactgc
    83641 accaacggcg gataaaactc cttcaaaact taagagtgtc aatcctttca tccgaaacag
    83701 ctcgtaaact cctattactg ctaagattgc tgctgtaagc tcaaccgcta tgcctccgat
    83761 ccatataatc ggaataaaca agactagcgc cacggctgct gtgaccacac gttgtttcat
    83821 gactgatccc ctttctcatc ttctgttttt tttacaccgc cgaatcgacg gtctcgattt
    83881 tgataagagg cgattgcttc ttcaagatgc gcaccatcaa aatcaggcca aagcgctttt
    83941 gtaaaataca gctcactata tgcgatctgc cataacagaa aattactaat tcgctcttct
    84001 ccacttgtac ggatcatcag ctcaggatct tgtaactctt taggcaagaa acctgtcatt
    84061 aaatgcttag caatcaattc atcatcgatt tcttctgcgt gtatttctcc ttttgctact
    84121 tcttcggcaa tttcttggac agcagtcacg atctctgctc tgcttccata attcaaagca
    84181 aaattcaata ccattccagt attgtttttt gtttgctcaa ttgcacgtct tacagcatct
    84241 tgcgtatgtt ctggcaatac gttttcataa cccatgacat gaactttgac attttcttta
    84301 atcaattctg gtacgaacgt atcaaagaag tcgacaggta gttgcatgag aaaacttact
    84361 tcatcttttg gtcgcttcca gttttcagtc gaaaaggcat aaagcgtcaa cactttcact
    84421 ccaagccttg atgctttttt tgtgactttc tttactgttt ccatgccttc tttatggcca
    84481 gcaactcgtg gcaaacgacg gttttgcgcc caacgaccat tgccgtccat gatgatggca
    84541 atgtgctgag gaattggtcc atcggtatta aattgaaatt cgcttttttc ttgaatatat
    84601 ttgttttttt gcggaaaaaa acgtaacatt ctttttcctc ctatacttaa aagattccca
    84661 ctat
//
LOCUS       DADGKS010000003        82993 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.003, whole genome shotgun sequence.
ACCESSION   DADGKS010000003 DADGKS010000000
VERSION     DADGKS010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 82993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 82993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..82993
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.003"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            558..3197
                     /locus_tag="JXV47_000171"
     CDS             558..3197
                     /locus_tag="JXV47_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAX1486246.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(3365..4063)
                     /locus_tag="JXV47_000172"
     CDS             complement(3365..4063)
                     /locus_tag="JXV47_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAX1486247.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            4281..5426
                     /gene="tgt"
                     /locus_tag="JXV47_000173"
     CDS             4281..5426
                     /gene="tgt"
                     /locus_tag="JXV47_000173"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010769586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HAX1486248.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            5523..5903
                     /gene="yajC"
                     /locus_tag="JXV47_000174"
     CDS             5523..5903
                     /gene="yajC"
                     /locus_tag="JXV47_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HAX1486249.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            6208..8805
                     /gene="adhE"
                     /locus_tag="JXV47_000175"
                     /gene_synonym="adhC"
     CDS             6208..8805
                     /gene="adhE"
                     /locus_tag="JXV47_000175"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HAX1486250.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            9034..10140
                     /locus_tag="JXV47_000176"
     CDS             9034..10140
                     /locus_tag="JXV47_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAX1486251.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            10157..11185
                     /locus_tag="JXV47_000177"
     CDS             10157..11185
                     /locus_tag="JXV47_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HAX1486252.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLEGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            11191..11670
                     /locus_tag="JXV47_000178"
     CDS             11191..11670
                     /locus_tag="JXV47_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HAX1486253.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            11686..12981
                     /locus_tag="JXV47_000179"
     CDS             11686..12981
                     /locus_tag="JXV47_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HAX1486254.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            12992..13816
                     /locus_tag="JXV47_000180"
     CDS             12992..13816
                     /locus_tag="JXV47_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAX1486255.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPETP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            13981..14880
                     /locus_tag="JXV47_000181"
     CDS             13981..14880
                     /locus_tag="JXV47_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAX1486256.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(15006..15875)
                     /locus_tag="JXV47_000182"
     CDS             complement(15006..15875)
                     /locus_tag="JXV47_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAX1486257.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            16028..17488
                     /gene="rhaB"
                     /locus_tag="JXV47_000183"
     CDS             16028..17488
                     /gene="rhaB"
                     /locus_tag="JXV47_000183"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HAX1486258.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            17485..18741
                     /gene="rhaA"
                     /locus_tag="JXV47_000184"
     CDS             17485..18741
                     /gene="rhaA"
                     /locus_tag="JXV47_000184"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HAX1486259.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            18755..19600
                     /gene="rhaD"
                     /locus_tag="JXV47_000185"
     CDS             18755..19600
                     /gene="rhaD"
                     /locus_tag="JXV47_000185"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HAX1486260.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            19602..19913
                     /gene="rhaM"
                     /locus_tag="JXV47_000186"
     CDS             19602..19913
                     /gene="rhaM"
                     /locus_tag="JXV47_000186"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HAX1486261.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            19995..21146
                     /gene="fucO"
                     /locus_tag="JXV47_000187"
     CDS             19995..21146
                     /gene="fucO"
                     /locus_tag="JXV47_000187"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HAX1486262.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEVSVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            21273..22031
                     /locus_tag="JXV47_000188"
     CDS             21273..22031
                     /locus_tag="JXV47_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HAX1486263.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIQTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            22131..22775
                     /locus_tag="JXV47_000189"
     CDS             22131..22775
                     /locus_tag="JXV47_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HAX1486264.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            22782..23789
                     /locus_tag="JXV47_000190"
     CDS             22782..23789
                     /locus_tag="JXV47_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HAX1486265.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            23805..24647
                     /gene="kduI"
                     /locus_tag="JXV47_000191"
     CDS             23805..24647
                     /gene="kduI"
                     /locus_tag="JXV47_000191"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HAX1486266.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            24667..25470
                     /locus_tag="JXV47_000192"
     CDS             24667..25470
                     /locus_tag="JXV47_000192"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HAX1486267.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(25719..26783)
                     /locus_tag="JXV47_000193"
     CDS             complement(25719..26783)
                     /locus_tag="JXV47_000193"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HAX1486268.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(26780..27865)
                     /locus_tag="JXV47_000194"
     CDS             complement(26780..27865)
                     /locus_tag="JXV47_000194"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HAX1486269.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(27878..28855)
                     /gene="mvaD"
                     /locus_tag="JXV47_000195"
     CDS             complement(27878..28855)
                     /gene="mvaD"
                     /locus_tag="JXV47_000195"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HAX1486270.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(28848..29792)
                     /gene="mvk"
                     /locus_tag="JXV47_000196"
     CDS             complement(28848..29792)
                     /gene="mvk"
                     /locus_tag="JXV47_000196"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HAX1486271.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            30114..30767
                     /locus_tag="JXV47_000197"
     CDS             30114..30767
                     /locus_tag="JXV47_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAX1486272.1"
                     /translation="MIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFYAN
                     PEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEVRV
                     YDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYDYY
                     KELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVAI"
     gene            30852..31757
                     /locus_tag="JXV47_000198"
     CDS             30852..31757
                     /locus_tag="JXV47_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAX1486273.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(31759..32391)
                     /locus_tag="JXV47_000199"
     CDS             complement(31759..32391)
                     /locus_tag="JXV47_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAX1486274.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            32711..33235
                     /gene="infC"
                     /locus_tag="JXV47_000200"
     CDS             32711..33235
                     /gene="infC"
                     /locus_tag="JXV47_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HAX1486275.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            33307..33507
                     /gene="rpmI"
                     /locus_tag="JXV47_000201"
     CDS             33307..33507
                     /gene="rpmI"
                     /locus_tag="JXV47_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HAX1486276.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            33560..33919
                     /gene="rplT"
                     /locus_tag="JXV47_000202"
     CDS             33560..33919
                     /gene="rplT"
                     /locus_tag="JXV47_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HAX1486277.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            34171..35508
                     /locus_tag="JXV47_000203"
     CDS             34171..35508
                     /locus_tag="JXV47_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HAX1486278.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            35556..37685
                     /locus_tag="JXV47_000204"
     CDS             35556..37685
                     /locus_tag="JXV47_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HAX1486279.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            37660..38349
                     /locus_tag="JXV47_000205"
     CDS             37660..38349
                     /locus_tag="JXV47_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486280.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(38757..39370)
                     /locus_tag="JXV47_000206"
                     /pseudo
     CDS             complement(38757..39370)
                     /locus_tag="JXV47_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(39506..39700)
                     /locus_tag="JXV47_000207"
     CDS             complement(39506..39700)
                     /locus_tag="JXV47_000207"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486281.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(39750..40190)
                     /locus_tag="JXV47_000208"
     CDS             complement(39750..40190)
                     /locus_tag="JXV47_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HAX1486282.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(40194..41039)
                     /locus_tag="JXV47_000209"
     CDS             complement(40194..41039)
                     /locus_tag="JXV47_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HAX1486283.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            41188..42606
                     /gene="pepV"
                     /locus_tag="JXV47_000210"
     CDS             41188..42606
                     /gene="pepV"
                     /locus_tag="JXV47_000210"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HAX1486284.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(42663..43610)
                     /locus_tag="JXV47_000211"
     CDS             complement(42663..43610)
                     /locus_tag="JXV47_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAX1486285.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(43833..44183)
                     /locus_tag="JXV47_000212"
     CDS             complement(43833..44183)
                     /locus_tag="JXV47_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAX1486286.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            44383..45462
                     /gene="pepA"
                     /locus_tag="JXV47_000213"
     CDS             44383..45462
                     /gene="pepA"
                     /locus_tag="JXV47_000213"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HAX1486287.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            45606..45926
                     /locus_tag="JXV47_000214"
     CDS             45606..45926
                     /locus_tag="JXV47_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAX1486288.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            45948..46412
                     /locus_tag="JXV47_000215"
     CDS             45948..46412
                     /locus_tag="JXV47_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAX1486289.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            46617..47222
                     /locus_tag="JXV47_000216"
     CDS             46617..47222
                     /locus_tag="JXV47_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HAX1486290.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(47261..48550)
                     /locus_tag="JXV47_000217"
     CDS             complement(47261..48550)
                     /locus_tag="JXV47_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAX1486291.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            48978..49457
                     /gene="rlmH"
                     /locus_tag="JXV47_000218"
     CDS             48978..49457
                     /gene="rlmH"
                     /locus_tag="JXV47_000218"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HAX1486292.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            complement(49647..51437)
                     /locus_tag="JXV47_000219"
     CDS             complement(49647..51437)
                     /locus_tag="JXV47_000219"
                     /inference="COORDINATES: protein motif:HMM:NF016309.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486293.1"
                     /translation="MDLPFSLKLNFGYKSEEQEYELLFFQDEASLLEYTPVKVKEFSN
                     LSFTFNSIDKHAKLYIPELDDYLIENQVKEENGDICYIPSDDNIIIYNRDQGKTVPLI
                     PGYYTLYVKIGETIFYSRFEIILKDLGTPEWEKMKIEIEKMVGGLARTFIPKKTSRRE
                     ITTSNYLMNDQLFQRILEFENNIPQAIVSLESLKKEAKYRIDKRYNWKPIGSKNLVDQ
                     KTISQLQIHPEKRGLLYTPSRIIKYDIIENQWIKFILSYFKNFSLLADRYLEKILQGI
                     IEEKKREDKFTSAYSQSVQNYNTNSYNRKIENLKNNQQKIKHFYAYILEFLDTPVMKN
                     ISSRRPINVPKSLVMNPKYNTIYKMYLKSRNNRNTLNFSNRYQYYWKSTDVLYEIWCF
                     IKIIRSLSLQGYTPISGWIFENDILSQELPFLHEDTTVVLSKNDIRINLVYNNSMEKE
                     YFSNTLDIPVKTSSKRNKPDIRLDIILQDKYYIGSLIFEVKYKKLDNILDNDKGRQRQ
                     QLMAYKQNTMSSILAFPEILTRSLQAVSAVFALYPSNEGRKKTAPKYYEKEGIFFHLL
                     NPSSDEKELSVKIQTSIEERISLFNQQSRN"
     gene            complement(51421..52425)
                     /locus_tag="JXV47_000220"
     CDS             complement(51421..52425)
                     /locus_tag="JXV47_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAX1486294.1"
                     /translation="MLGDSLVVLAGLSGTGKSQLVTSYAKALQLSDTQIKFISVRPFW
                     EDDSDLLGYADTVNSVYRPGDSGLIDALLEASRHKENIYMVCFDEMNLARVEHYFSQF
                     LSVLEMEPNTRKIKLYNEDLENKLYNSSTYPSTIEVGQNILFVGTINTDESTHQFSDK
                     VLDRSNIISLELVPFHEISEVNDYIQSDQKKRNQLKYDDFKNFKNSNPTNGLTQKEKE
                     MFWKLHLAINSKDKNIGIGWRILKQIDEYLKNLPVQNDLSRKEAIDIQLVQRVLSKIR
                     GSDEQLSELVGKWNENDLKQVGEFEQIINEYPESSDFKYTKKILLQKARELNLHGFTL
                     "
     gene            complement(53396..54538)
                     /locus_tag="JXV47_000221"
     CDS             complement(53396..54538)
                     /locus_tag="JXV47_000221"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486295.1"
                     /translation="MKALTISFMEDVFHSLDLEHLNKLAKVLPQKLSGSSIIPKNPSD
                     SFKNRLFNQFLKEKNLRYIFKYISSGYFHDIVANDENIYKSTSIQSIEGFFEEIKNKE
                     LESPFSFYIYLIEQTDEDNIVDFFQNIDGLRTFKNNSLIYIQNKKKNKGCTDISLEYK
                     KMEDLLTLYKKDKIDAENREKVLLKENERLKKKIEKNNNDKIRELSKLEKKFLAEKEC
                     EINRYKEEITNSLLKLKNSESKYLNLEKKFSILNSTLKNKENEIVELKKRCNSLINTS
                     KTVKTISHQTKESIKKILLIGVPGKIVIREDYNFIITNPDTPLEDIIKIIEENDINEL
                     WITTFQLIPRMKKKIIQSLKNKIKIQELNDFTMLMKEENINGFKTR"
     gene            54868..55176
                     /locus_tag="JXV47_000222"
     CDS             54868..55176
                     /locus_tag="JXV47_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAX1486296.1"
                     /translation="MFQNKGQRYVTKGVMDSLLVELQTLCWNLIDQNVQKKLPLDYLQ
                     IFEFSIEKGNQKLVHRQEEPEARKEYLISPKLRLESVSQKIWVIDSGEYQTMLLPEEY
                     "
     gene            55203..55502
                     /locus_tag="JXV47_000223"
     CDS             55203..55502
                     /locus_tag="JXV47_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HAX1486297.1"
                     /translation="MLETAIEVLEKCAQLVTTPEEWGYESVTMEKEEIEMGTLPKNVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVCGLLVEGRLVWSQIGGTNE"
     gene            55676..56221
                     /locus_tag="JXV47_000224"
     CDS             55676..56221
                     /locus_tag="JXV47_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HAX1486298.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEEKEKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFSRGNDEQSLE
                     ILTTIFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLSDHSLLFQ"
     gene            56377..56673
                     /locus_tag="JXV47_000225"
     CDS             56377..56673
                     /locus_tag="JXV47_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486299.1"
                     /translation="MKVDGECLTSSYKSIYEFFEEKGLDTDLLYQFYIAFRGQQLSFP
                     MKMYDRELVAQKIETMIQENHSIDSRKLTDRYGFSTRWIQSIIRQQQKEQHVHG"
     gene            56666..57556
                     /locus_tag="JXV47_000226"
     CDS             56666..57556
                     /locus_tag="JXV47_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HAX1486300.1"
                     /translation="MANEETVGLRIIEEAFKLPMVKVDRRAFLIQTFQGNVSDIEGLI
                     EKGPQAFLSKEMLDREAQKCIQSITLKSSAVSLATGLPGGIAMAATIPADLLQFFGYS
                     LRLAQEISYIYGFKDLMGETGEFSEEAKNTLILYLGIMLGVTSAGSAVRAMSGKLSTQ
                     ALKKIPQKALTQTLYYPVIKRVLGIFGTKLTKNTFAKGISKAVPVVGGVVSGGINYLS
                     MKPMATKLQTELGKNVAYTEKNLQQDLDILEGEFEEVSSDIVSSDTVLSQLERLSHLL
                     ETNMITEEEFQQLKQELLKK"
     gene            57638..58648
                     /locus_tag="JXV47_000227"
     CDS             57638..58648
                     /locus_tag="JXV47_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HAX1486301.1"
                     /translation="MKAKRLFLLGTILLLGGCSTVSQNEQKKQVDSTTYETETTRKES
                     STKEIETTTQETKTTESSSKATSSDTSDFQIKQELWDTNKASQLATFVPQWGKTLGQE
                     YKSYNPQNNVSLYGTPLPSAVIDGNWKMAINEAPVTVQWSEDGTGNAGFNLVAVYSDV
                     ETGEYLGQHVYFFGFQNGQPKVYLTQQNQGNENNYLYFNETQNQQLKQGFTDIINGQT
                     PQTPVVEESTQQATTTTTQSTSSSGISNWEAAKETVLNNKALWIYESPDKNEANTNII
                     ESTQYRKDLMQDENGEFYPVDISTDDIGNTVMNGGKQFRVYTDGRISQRIGMTNNFQM
                     IK"
     gene            complement(58735..59694)
                     /locus_tag="JXV47_000228"
     CDS             complement(58735..59694)
                     /locus_tag="JXV47_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAX1486302.1"
                     /translation="MTYTHLTTDELVIIESYFKINQSVAKTAHCLNRSRQTIHKVYLF
                     FKKGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDEFFIQSVASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            60234..61157
                     /locus_tag="JXV47_000229"
     CDS             60234..61157
                     /locus_tag="JXV47_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486303.1"
                     /translation="MATNYAKKINFDVDKLYKSLIVVPKNKSEDGNYELEVLQFKIEQ
                     KSSERFMSNQLVKIKKWLPMIDQLVSNNKEAKNLCIFVLLLHGRVINLVNRKSTTKFA
                     NSFWFLENINETVEKNGVYKGDFHFQNAETIEREHHYFDLLVNTVVELAKWAKSNETY
                     SQVLKRIMSQETSFIYELSKSNLKYTYNEDELEILDNPENSQWIKELKREDFIETLRI
                     LKSLFDLKLAKATIMGIERDSYYWEEIGLYAPQIEGEDKEKRIDNIINYINSLSEPLK
                     CRGLDFIGTLGWTETYYEKIYKEIIEQYFPK"
     gene            61340..64015
                     /locus_tag="JXV47_000230"
     CDS             61340..64015
                     /locus_tag="JXV47_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HAX1486304.1"
                     /translation="MKMNHTSIQKHLQLLNTLGISYVNLRTFSTLNKKTVSHIFSTAD
                     SQAIINYLEKQKLSEGTVNITYNPIKQEVITQKKHSVRDNDIEKIRFVFIDIDPKRKE
                     GSATDSEKKKAENVMEQVERYLKEKRIESFVKVDSGNGYHIFLPINEQPNNHETILTI
                     QNFLQLLHRRFGVEDEVDIDTSVYNPSRLCKLVGTPAVKGKSTKERPHRLSSFLSIPD
                     NIDRSNCFKILEQIVEENSMMSTSRVKSHPSFREVLPFIQADYKQWLAHYPELTYTIK
                     EGDHKGVTLLIFDECPLRKHTNNSNGSCLSVTADNKIRFHCLHASDKNKDIQDFVKKY
                     PLPKPVNPSVESLESNQEYYFDQFKLNQEGVFLVKEGQEEKVACPMFIKQIRKNIEQK
                     VITLVLAYYVDHCWDEIEIEGGCLQTNNFKQLAKHGLIIKARREAEVVDFLQIQRENA
                     PIFFEHESLGWKKENEAMIFQLQDSFGREIPSVLTKNSCYQLTTNGTEAEFDALVHKY
                     VLGTNLELAWSIGIASIVLGYLNVTKANTFLSLLINLQGKSTTGKTTTLHFIASLFGN
                     PTTVLRNMNATNKAIIKLASNNQGGVPLILDELGAATQNNFSSLIYQLASGEERLRLD
                     SNCQLMPQETFSVLTLTSSEERLENYFNEKLTGLKVRYIEFSDIKFTKDANHAEKVKS
                     LSSNTFGWGIKLFLLKLFEQGIAKIEATFVEAQKKIWAVLPEHSLKQRIGNNLALIYS
                     GALLIQDILGYPLRLEHIQTVLINSYEQLIVDTSLGSEQTVFDRVKTLLVMNSHKFLT
                     NSDNKHTPSTIWGKVSIQKNGDIKVNIFPIPFEDLLRREFQVKDLTYLFRQLLDSGNM
                     CAEKGRRTKRIHMNRQVLPTYEILLPSSLKSYFRL"
     gene            64197..64436
                     /locus_tag="JXV47_000231"
     CDS             64197..64436
                     /locus_tag="JXV47_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486305.1"
                     /translation="MTKNKMTLKAEVLLYIQEHFSNQAFFTKPIYLAFEIRGVSAGSI
                     GGTLQALKNEGYLENHFVQRSFNGRVAKEWYLVHS"
     gene            64452..65825
                     /locus_tag="JXV47_000232"
     CDS             64452..65825
                     /locus_tag="JXV47_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAX1486306.1"
                     /translation="MRVACYDRTSVYEEAKISNDAQYDAVKEYVLEKYEQIPQRFSDK
                     GESGGKADRPAFRQLRAWVCASEEEGVIYVWRYDRLARQAKIALEFIELCQQHQVQVY
                     SISEPLPASFSHASTNKLFVQLLFTFAEQQRNVIIENVRAGLAYKKQQRQYLSSAVPY
                     GYRLVNGKIQQEAHEAKVVRHIFQLYLTKKYGYKKLCQRLTQQKFFFRERPFQPYHIY
                     SILKNPLYYGEIKGGSLGKYLGTFEPILSKTIFLQAQEIRQSRCTAKKDTYPYLLRQK
                     IRCPFCGRHLSSKYQWNTKKTKTLHYYHCTDRSCQGIFLRAERVESEVLEKIQAFFQY
                     EGVYQALIAQLTQQLAEKRKDEKHKVIQQKKQEAQWLKAFEEGNCSLEELKQQLQALQ
                     KPRSTSSFLSLQQCEAKVKEWLQLKDLSSRQLLCDHVCRIEVTKEKTVCGIYFRQMTQ
                     NILEGNE"
     gene            65829..67466
                     /locus_tag="JXV47_000233"
     CDS             65829..67466
                     /locus_tag="JXV47_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAX1486307.1"
                     /translation="METTPTKRVALYIRVSTQEQALEGHSIQAQEQNGRQFAERMSYE
                     VVEVYADEGISGKSTKNRFAYQRMMNDARNHRFDLLVIWKLTRLGRNMLDVLQTVEEL
                     LRYDVGLHSISEQFDVTTSTGKLMLQLLGSFGEFERNQIAENVQMSMQSLVKDKKRYA
                     GGRRLGYVSGIDTNGQKQLVIEPEEAKIVRLIYAKYLGGAGYRAIANFLNRQGYQTVK
                     KNAFSTTAVKDILRNKIYAGYLEYARYINWETKRRKGKNPKPILVKGTHEPIISEEDY
                     QKVQERLVLEGKQPKWNHTGENVLTGLLRCPECGAPMAASNVTNTLKDGTKKRIRYYS
                     CSVFRNKGASVCHANSIRAEQAETFVADRLKEIVQLPEVLPRLVAALNEEIVRQSQPL
                     EQELVVLLERKEELKTKIEKWEAALEDSPELFPMLKDRLDELTEKRRQLHIRENEILG
                     IFQQQGEPIQVKDVQRILTSLDRFLAQSEKKQVKALYRTFIEKITFDPNYKEILEITM
                     KFTPAVVQQLNEQYQIAVSKTKDTAIFVLKTPFTLTI"
     gene            67629..68561
                     /locus_tag="JXV47_000234"
     CDS             67629..68561
                     /locus_tag="JXV47_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486308.1"
                     /translation="MKKMGKCILCEKYTELTKEHVPPKKSGNTGGKKTRTGNLDDFLK
                     SDFTKGDFPKGIKRKPQGNVYYTLCSKCNSFFGSEYVEEYIRFAEDNKNFLYNNTSLK
                     NGKSDLTHSIKKMNSLRVAKAIVAMFFSLNGDEDSMDKPFLDSVREYLSNPKSTLFPH
                     EDYKIIMNYYLPIGAPQNSKIKIPNDIVNDGDTHNVIKGFMPLDLSTGRKIRFSEIQY
                     EGIGFTLIDLKNSTFEIKEGLDLKNLLCADDKIKKIQLYKVPILTPTVLTMLEMENNI
                     NYIDSGSDLLIRWQVITNFLMELKKYSNTQTKFS"
     gene            68686..68943
                     /locus_tag="JXV47_000235"
     CDS             68686..68943
                     /locus_tag="JXV47_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HAX1486309.1"
                     /translation="MEDSPELFPMLKDRLNELTEKRRQLQIRENEILGIFQQQGEPIQ
                     VKDVQQILTSLDCFLIQSEKKQVKALYHTFIEKITFDPNQK"
     gene            69175..69579
                     /locus_tag="JXV47_000236"
     CDS             69175..69579
                     /locus_tag="JXV47_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit M"
                     /protein_id="HAX1486310.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFLASHIYGKILSAKFE"
     gene            69598..72255
                     /locus_tag="JXV47_000237"
     CDS             69598..72255
                     /locus_tag="JXV47_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAX1486311.1"
                     /translation="MEELKERIVNYVIENSEIKNKWGNNTAQKISEKLNVSRNIVSQY
                     LNEFVKDGEFGKINTRPVIFFSLPEKVPNQQIFSSSEEAEKWYDSSFRVGIERVIGSQ
                     GSLRNVIAQIKAAIYYPPNGLPILLHGETGTGKSYLANYVYKDLLANNYIEEKASFIS
                     VNCSEYANNPELFLSNFFGHVKGAYTGAEDGRKGLAELANNGVLFLDEIHALSNECQE
                     KLFQFMDTRKFHRMGDNENWYTSSCWIIFATSEPPEDKLLSTLLRRIPVKLTLPTLDS
                     RSLYERKQLIKIFFKSEEERLAKKILISQQLLDFLLNYRFSENVGNLKNIIQLTCANA
                     FYFLDDLEELYIQMYHLPQWVNFNGMKVMKRQNELKYIQMDDLEKVDEVFNINELIEY
                     LYQTWKKDTDKQQLFEKYDRYFRQKNVDIQNNSALTYPTYQEIRFRQYVKEIERDFQI
                     EFDYYYLQITSIFLNSWIYQIQLTSDDKLYSFINDINSWCSREVQLVNRFIQIGDIYL
                     TKIQKNVLVILFKLMCSKEFQQKRLALILAHGDLTATCIASTANRIVERYIYDAIDMP
                     LMTSSSEIADKINRYLQECTGYEEIILLVDMGSLEKIYLNLELDAQKKFGLLNNVSTR
                     MAIDVANQILLDLPLKQILEQVKENQNVDYIYESSNIKKDMIVCSCASGLGTSFKLKK
                     ILEDSFPRDTDLVIETCDYYSLVNENYLSELRKENNILFIVGTLNPHLEDVEFFSIED
                     MILGMNISKFSNQLNRHFNDNELKVLNNNILKNFSLTNLMEQLTILNPTKLLERVSDA
                     IYILQNDLGISFDNNTCFGLYVHISCLIERLVKQNTLEDEIYFNETSEEFQKFQTHFK
                     QSFSVVEHYYSVDIPIHEVKYVYDYVKRA"
     gene            72327..72803
                     /locus_tag="JXV47_000238"
     CDS             72327..72803
                     /locus_tag="JXV47_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAX1486312.1"
                     /translation="MSIVMSRVDNRLLHGIIVTQWAPMSKANRVMVIDDSVANNDIQK
                     SSMRLARPAGMAVSIITEETAIANFKKGKYDQEKVFVIVKEPETILHLVDNGIRIDRL
                     IVGGTVVKDNALQLSSRAYASDENISTYKKLLDSGVEIVTQFVPADKAQEIQSKLG"
     gene            72817..73605
                     /locus_tag="JXV47_000239"
     CDS             72817..73605
                     /locus_tag="JXV47_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1486313.1"
                     /translation="MHFTIFQIIMLTILAFIKHVDYYGIPMIFVNYAVFWGLFTGILM
                     GDIKTGLIVGGTVQLMSLGVAGFGGSSVPDYGTCAIIATAFGSQLGVEAGLAIGLPVG
                     MLGVQLDVIVKILNGFVVRKSQEYANKREFKKMNSVLWLGPIFFGLSAAIPVFIAVTL
                     GQSAVNYVLDVLPNWFMDGLTLAGKMLPAVGIAMLLRFMPTGRYISYLLVGFFLAAFL
                     KVPIIGAAIIGFALAFNVYHRAEKDAQITASAGASDVGFIGEDE"
     gene            73607..74404
                     /locus_tag="JXV47_000240"
     CDS             73607..74404
                     /locus_tag="JXV47_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010238514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAX1486314.1"
                     /translation="MSEKYQVTKKDLRKANYRWLMSVCTFNYQTQQGASVTYALSPIL
                     RKLYKDDDEYIEALNNHFQYYNTQPWLAAIILGACVAMEEKQGLEAKDAINDFKVGTM
                     GPIAGIGDSLLMTMIPTIMGSIAAYMALENNPVGIFLWFILIMVIFFFRMRGFEFGYK
                     QGMKIVTEYGEKINYLTEAASVLGLTVVGSLIASVISVSTPLKFTFGEVSMKIQPMLD
                     KILPTLIPVIITAAAYYLLSKKKISMTILILLVIVFAMVMAAFGILA"
     gene            74423..74818
                     /locus_tag="JXV47_000241"
     CDS             74423..74818
                     /locus_tag="JXV47_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAX1486315.1"
                     /translation="MRRLIIASHSILAEGFKETLEFLTGMHNQISSLCAYVEEIDDID
                     EQIKELVDTTDEIIVLTDMAGGSVNQKFFTYISDRVHVIAGMNLPLAMSIALQLGNDN
                     LDIGAIIAEAQQQIIYMNNQKSEERIEDE"
     gene            74820..75941
                     /locus_tag="JXV47_000242"
     CDS             74820..75941
                     /locus_tag="JXV47_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HAX1486316.1"
                     /translation="MNCLNNIWLHKGEESRTISPENKNGEKGKAAMTASHLGIGRKGS
                     PSVPINAGETITLAEMEGPGILRHFWMTVTDKTIAGSFVLRDLILRIYWDDESTPSVE
                     SPLGDFFCNGFGTRCEVNSLPIVVNPTSGMNCYFEMPFRKKAKITLTNEHPEFIKHIF
                     YTFNYALTEVPDDAMYFHAKWNREPITTKGKDYTLIDGIKGTGYYVGTYFALCALERY
                     WWGEGEFKFYIDGDEDFPTITSTGAEDYFGGAWAFHKKNFGERAYAQNFNTLFMGYPF
                     QSKRDHTRDYFSAGKPNPNPVHGFGDDALPMHGLYRWHLPDPISFKENLRVTFQTLGN
                     DDIKLYERQDDISSVAYWYQKEPHEFFEKLLDREERIPR"
     gene            75961..76830
                     /locus_tag="JXV47_000243"
     CDS             75961..76830
                     /locus_tag="JXV47_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAX1486317.1"
                     /translation="MYGSIEAGGTKFVCAIGNDDLKVLERVSFPTTTPNETMSLVIDF
                     FNHYKEQLESIGVGSFGPIDIHRESKTYGHITSTPKTAWKNFDFVGTLNKHFEIPIAW
                     TTDVNAACYGEYVSGHGKGLSSVVYYTVGTGIGGGAIQDGIFVEGFSHPEMGHTLVKR
                     HSGDTFSGTCPFHHDCLEGLASGPAIEMRTGTKGQDLSIEDPFWEIEADYIAQCACNT
                     TLMLSPDIIIFGGGVMQQEHLKKKVQRRFLELINGYVDTPNIEEYIVTPKLADNAGTI
                     GCLTLAKDVRINS"
     gene            77031..77540
                     /locus_tag="JXV47_000244"
     CDS             77031..77540
                     /locus_tag="JXV47_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HAX1486318.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            77640..78290
                     /locus_tag="JXV47_000245"
     CDS             77640..78290
                     /locus_tag="JXV47_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486319.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            78741..79679
                     /locus_tag="JXV47_000246"
     CDS             78741..79679
                     /locus_tag="JXV47_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAX1486320.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            79692..80744
                     /locus_tag="JXV47_000247"
     CDS             79692..80744
                     /locus_tag="JXV47_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1486321.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            81010..81645
                     /locus_tag="JXV47_000248"
     CDS             81010..81645
                     /locus_tag="JXV47_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HAX1486322.1"
                     /translation="MIFLQKYGFYFLLLGVISDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFIGTSKTLAILAVATVGLYGIGDCIFT
                     GLFSINTNESSWNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYGLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            81836..82627
                     /gene="msrA"
                     /locus_tag="JXV47_000249"
     CDS             81836..82627
                     /gene="msrA"
                     /locus_tag="JXV47_000249"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAX1486323.1"
                     /translation="MLDVEQMEIDLYNIILNRNTREWERTQFEEAKEDLAKMSIKQVI
                     EKLEVNLRPLALRDNLTPDAMDFYLRITGESASAKAYDYAKHKITSPLYQERAIFAGG
                     CFWCMVEPFETKPGVISVLSGYTGGETKKPNYDQVSGGYTGHVEAVEIIFDTRQITYE
                     ELLEIYWQISDPTDAFGQFQDRGKQYRSILFVVNEKQRQLAEKSREQLIQSNRFSRPI
                     VTEIRQAKTFWPAENHHQQFYQKQPKRYKKIKHSHQLHLFFQRHR"
BASE COUNT        27101 a        13932 c        16950 g        25010 t
ORIGIN      
        1 aaaaagccga gctctcgata agctcggctt tcttgtacct cggaaggatt caaataaaca
       61 gaaatgattg taactttcca tcatacatgc aaagcacggt gttgaatttc ttcatgttaa
      121 acaaaaattt tgttttcgtt acatcttcaa catttgaaac atctcttgtt cctattcaat
      181 tttcagacgt ttacgttatt caattgttac gtatcgcatt acttcttgtt tcggatactt
      241 cgtgatccaa acatccatac gcattcacta tttataggtt tgtactctac acgcatgtct
      301 gggtgaaacc tgtacttcta acaactttgt ttgcttacac tgttctatcg agaaattctt
      361 ctgtctattt gatggtatcc tccttcctta catctatata atagcatcct ttggtagcgt
      421 ttgcaaatat aagcacttta aattttacgc tttcttaaca aataatcgat aagcccttta
      481 tttgaagtaa ataaaaaaag gatgttatag taaaataagt accttttttt gtacgaagat
      541 tttaaaggag gaataggatg gaagaataca agcagacaat agaagaagta aagaaggtaa
      601 cagaagcaga tccagatact gggttgtctt cacaagaagt ggatgaacgg cgaaaaaagc
      661 agggattgaa taaattcgat gaggcgccga aagaatcgat gatcaaaaaa ttctttcgaa
      721 gcttgtccga ttttacaacg atcatccttc ttgtagcagc ggtgatttcc ttttataccg
      781 catttgctac agaacatggg gatttatttg aaggactgct gatcatcgct atcgttgtga
      841 tcaactcggt attggcgatt gtccaagaag gaaacgcaga aaaagcactg gaatccttgc
      901 aagatatgaa taaacaaacg gcaactgtca tacgagacgg caaagtgacc actgttgagt
      961 cagagcaact ggtagtgggt gatattcttg ttttagagtc cggtgatgct atttctgccg
     1021 atgcccgttt gatcgaagca tcacaattac gtgtagaaga atcggcgttg actggagaaa
     1081 gtgaagcagt tgaaaaagat gcagcattta ttgctgaaga agatgagtca ttaggtgacc
     1141 aacttaatat ggtatttaaa ggatgtacgg ttgctgcagg tcgtgggaaa gcgatcgtca
     1201 ctgccattgg catggctaca gaaatgggta agatcgcgga tcttttgaac gaaaatacta
     1261 tgcaaaaaac acctttacag gtccgattga atcagctagg caaacgaatc agtatgatcg
     1321 ctttagcggc tgcggcttta gtatttgtga ttggtgaact gcaaggagaa ccactccttg
     1381 agatgttcat gacttcgatt tccttggctg ttgcagctgt accggaaacc ttgactgtta
     1441 ttgttacgtt gacacttgca tacggtgtgc agaagatggc gaggaaacat gcgatcatcc
     1501 gacagttgcc agcagttgaa acgctaggaa ccgctaatgt tatctgctca gacaaaacag
     1561 gaacgctgac acaaaatgaa atgcgcgtcc gccgggtatg gagcaaagaa gatgaagtaa
     1621 cgaatatcga agattcaatg acgaacagcg cgatggaaat attgaaaatg gctgcactat
     1681 gtacagatgt gacggtcgag caagaagatg acgaccttgt tatcaaaggt aatccaacag
     1741 aagtagccat cgtaagggct gttgaagaga attatcatac aaaggcagaa ttagaagaaa
     1801 aatatccacg agtaaacgag cttccttttg attctgaacg aaaaatgatg acaacagttc
     1861 accaaatggg cgaaaaatac atctcaatca ccaaaggagc attcgatgtt cttgctccgc
     1921 gctttagttc aggcgatgta gaacaagcgg cgatcgttaa tgatcgcttt ggtaaacggg
     1981 cactgagagt gattgctgtt ggttatgcta cttatgacga agaaccgcaa gatatttctt
     2041 ctgaagcact ggaaaaagac ttacgtttga ttggtctgat cggaatgatc gatccaccac
     2101 gtccagaaag taaaggagca atcaagcgag cgaaaaaggc tggcatcaaa acagtcatga
     2161 tcactggaga tcatgtggtg actgccagtg ccatagcgaa agaattaggt atcttgaatg
     2221 atccgtcaga agcactttca ggatcagaac tgcatcaatt atcagacgaa gaattagatg
     2281 cgcgtgtcaa agctctctct gtctatgctc gggtaacgcc agaagacaag atccggatcg
     2341 tcaaatcttg gcaacgtacg ggtgcagtcg tagcgatgac tggggatggt gtgaatgatg
     2401 caccagcgtt gaaagcaagt aacgttgggt gtgccatggg gatcacagga acagatgtgg
     2461 cgcaaagtgc cgcagatatg attttgacgg atgacaactt tgcgacgatc gtagacgctg
     2521 tcagtcaagg acgttcggtt tatcagaata ttcgtaaagc tatcaacttt ttgctaagct
     2581 gtaatatttc ggagatcttt attgttttga ttgcgatgct gttaggatgg ggagcaccat
     2641 ttacagctgt gcaactactg tttgtcaatg tagttgctga tggacttcca ggatttgctt
     2701 taggaagaga gccagcggaa cacggcatca tggatcagcc acccattccg aaaaatgaag
     2761 ggatctttgc tcgaggttta ttgcaaaaaa ttgccataaa tgcaggggtc ttcaccatcg
     2821 taaccttgtt tggttattat ttaggtagtt atgtcgatac tatcagccca tgggtagacg
     2881 caagtcagca tgtcggtcaa actgttgcat tcttgatctt agcttattca tcgattctgc
     2941 atgtgttcaa tgtacgcagc agccaatcga tcttcaaagt caatttagcg accaataaag
     3001 ctttggtaga aatggcgtta ctggcattag ctattacaac ggctgttgct ttgctgccat
     3061 ttacgcaaga actattcggc ctagtacaca tcagtttgaa tcactggttc ttggtaggga
     3121 ttttatctat cgtaccaatc gcggtgaatg aactgatcaa gttccatcga ttaccggaag
     3181 cagaagaaga ggaatgatta actgtttcta agttgatttt ctttttactg gaactataca
     3241 aaaaggaggt gtgacatgaa tgttgtcaca cctccttttt gctaatgggc tgaatgtttc
     3301 ttttactgcc tctcgataaa cggtgttctc ctgccacccc ctcggtcaca agtcacactc
     3361 tcttttaaat atcttttggc aattgttcat aaaatgctgc ttttgttgca gaaatgtatg
     3421 ggctgagcca tagataacca ataccagcag ttgctaatgc taagatatgc cagccgataa
     3481 atgaaagatc taaccagaaa agttgtcctt tataaccatc catcaatttt cgacttgcag
     3541 tgatcgtatc cagtacttta ggtgtttgtc ctgtttcttg gacgatatcg tagtaaataa
     3601 aatagctttg agaataagaa tagcttttaa tgattccagg aataactaat agcaaacccc
     3661 ataatgttgt aaagatcgag atcagcacag ctaagctgat cactccgccg ataaacaaac
     3721 ctttgaatcc acgaaatgca tctttgaatg gttcgatctg atctttttgt ccacgtaaaa
     3781 tatcaagata agtccaagaa ataccgctca tgaacaaagc gctaatgatg ctggaaataa
     3841 ttccgccacc gcctcctgaa ctaccgcctc ctgaagttgt cgcttctgag acgctcgctg
     3901 atccatcata tatggtggtg gcaaacaaga taataggaat cataataaga agaatagtag
     3961 caataccaat caatgtaggg attagattta gtaaaacagc ttgtccccaa cgtcctttta
     4021 gactctcttt tgcttggcgt tttaattctg cagaagattg catgattttt ccctcctttt
     4081 ctttaataac accaatatac catgtatcaa aaaatatttc tgtcataatg tttttctttt
     4141 ttttgttatt cataaaaaaa ggataaaaaa aagaatatta aataaagtag aaggaagccg
     4201 agggaacttg caaaaagcac ttgaaacgat tatgatggtg ggagttgtca agatatttta
     4261 tatagaaagt agggaaatga atgacgcaac ctgccattcg ctatcgttta atcaagaaag
     4321 aaaaacatac tggcgcgcgt ttaggggaat tgatcacgcc acacggaact ttccccacac
     4381 caatgttcat gccagtagga acattagcta cagtaaaaac aatgtcccca gaagagttga
     4441 aagaaatggg tgctggcgtt attttaagta atacatatca tttatggcta cgccctggtg
     4501 aagacttagt agaagaagct ggcggactgc ataaatttat gaactgggat caaccgattt
     4561 taacagattc aggcggcttt caagtttttt cattaagtga tatgcggaat atcgaagaag
     4621 aaggcgtgca tttcaaaaat cacttgaacg gttcgcgtat gtttttatca ccagaaaaag
     4681 caatcaacat ccaaaataaa ttgggctctg atatcatgat gagttttgac gaatgtccac
     4741 cattcgatga aagttacgac tacgtgaaaa aatcagtaga acgtacgtct cgatgggcag
     4801 aacgaggatt gaaagctcat gctaatccag accgtcaagg attatttgga atcatccaag
     4861 gagcagggtt tgaagatctt cgtcgtcaaa gcgcgaaaga tctagtcggg atggatttcc
     4921 ctggttactc aatcggcggg ttatctgtcg gggaacctaa atcagaaatg aatcgtgtat
     4981 tagaattcac tacaccgttg atccccgaaa acaaaccacg ttacttgatg ggtgtcggtg
     5041 ctgctgattc attgatcgat ggtgttatcc gtggagtaga catgtttgac tgtgtcttgc
     5101 ctactcgaat cgctcgaaat ggcacatgta tgacttctca aggccgtcta gtagtgaaaa
     5161 atgcgaaata tgcccatgat ttccgtccaa ttgatgagaa atgtgattgt tatacatgta
     5221 aaaactatac acgtgcctat atccgccatt tgatcaaatg tgatgaaaca tttgggattc
     5281 gtttgacttc ttaccacaat ttatacttct tgttgaatct aatgaaacaa gtacgtcaag
     5341 caatcatgga tgataatttg cttgaattta gagaagcctt ttttgaagaa tacgggttca
     5401 ataaagaaaa cgcaaaaagc ttctaaagga aaatctttta aaaattaagt aaaaaactag
     5461 tgttatcagc atttttctgc taaagtgttt tttgtagata cagaattagt gaggtgaaaa
     5521 aaatgggaac attaccaatg cttgtgatgt ttatcgcgct attagcaatg tggtttttta
     5581 tgtcacgttc gcaaaagaaa caacagcaag aacgtcaaaa cttgttagat agcatgaaac
     5641 caggtgattc agtcgtaacg atcggcggat tacatggagt tgtttcagaa atcgacaatg
     5701 acaaacggac agttgtttta gactgcgaag ggatcttcct tgagtacgat cgtgcagcaa
     5761 tcaaaacggt caaaccaggg actgtcgtaa caaatgatgc aacgactact gttgaaacaa
     5821 cagaagaacc agctgagaca gttgaagtaa aaactgaaac aacagaaacg ctggaagaga
     5881 cagaagagaa ggaagaaaaa taagtatcaa agcttattta aagacgaggt agggcagaaa
     5941 gatgtcctac ctcatttttt attcaaaaaa gaaagagata agagcatggg atatattgct
     6001 caatattgaa taatcgggtg tgtcatataa ataataataa ataactttat atatttttct
     6061 atacaaacac ctgtaaataa agcaatttta tatttaaaaa taactgtgaa aaaaatcaca
     6121 aaaaagtgtt tacatagaaa aataaatatt gtatgatata catgtgaatt atttaacaaa
     6181 taaccatgac ccattaggag gataatgatg gctaaagtaa tagaaaaaga aaaaacgaag
     6241 acaattgacg tacaagcaat gattgatgat ttggcagaaa aagcaaatgc agcattgaaa
     6301 gaaatggaaa gctttgatca agaaaaagta gaccatatcg tgcatgaaat ggcaatggca
     6361 gctttggatc aacatatgcc attagcgaag atggctgtag aggaaacagg ccgcggtgtt
     6421 tacgaagata aagcaatcaa aaatatgtat gcgtccgaat atatttggca taatatcaaa
     6481 catgataaaa cagttggtgt gatcaatgaa gatgtccaaa aagggttgat tgaaattgct
     6541 gaaccagtcg gtgtggtttg cggagtaact ccaacaacga atccgacttc cacaacgatt
     6601 ttcaaatcaa tgatcgcgtt gaaaacaaga aatccaatcg tttttgcttt ccatccaagt
     6661 gcccaaaaat cttctgcaga agcagcacga gtggtacgtg atgctgctat cgctgccgga
     6721 gctcctgaaa attgtatcca atggatcgaa catccttcga tcgaagcgac ttctatgcta
     6781 atgaaccatc caggtatcgc gatcgtctta gcgacaggtg gagctggaat ggtcaagtct
     6841 gcttactcta caggaaaacc agctttaggt gtaggtccag gtaacgtacc agcttatatt
     6901 gaaaaaacag caaaaattaa acgtgcagtg aacgatttga tcgtttcgaa aacatttgat
     6961 aatggaatga tttgtgcttc tgaacaagct gtgatcgtgg ataaagaaat ctatgcagca
     7021 gtaaaagcag aattccaagc acaccaagtt tatatcgtaa aaccagatga attgcaaaaa
     7081 ttagaagatg cagtgatgaa cgaaggaaaa tatgcggtca atccatcaat cgttggacat
     7141 tctgcgatgg aaatcgcaaa attggcagga atcagtgtac caaaaggaac gaaaatgctg
     7201 attgctgaat tggaaggcgt aggcccagat tatccgctat caagagaaaa actttctcca
     7261 gttcttgcca tgatcaaagc taacaacacg gaccatgcgt ttgatttgtg tgaaggtatg
     7321 ttgaatcttg gaggattagg acatacagca gttatccatt cagaaaacga agagttgcat
     7381 gtcaaattcg gtcttcgaat gaaagcttgt cgtattttag tgaatacacc atctgcagaa
     7441 ggcggcatcg gtgatatcta taacgaaatg attccgtcat tgactttggg atgcggttct
     7501 tatggtaaga actctgtttc tcgtaacgtc tctgctgtaa acttaatcaa tgtcaaaact
     7561 gtagcgaaac ggagaaataa catgcaatgg ttcaaattac cgccaaaaat cttctttgaa
     7621 aagaactctc tattgtactt agagaaaatg gaaaacgttg aacgtgtcat gatcgtttgt
     7681 gaccctggta tggtccaatt cggttactgc gatacagttc gtgaagtatt ggcacgacgt
     7741 aaaaatgatg tgaagatcga agtcttctca gatgttgaac cgaacccatc gacaaatacc
     7801 gtatacgcag gaacgaaact gatggcagac ttcaagccag atacagtaat cgctcttgga
     7861 ggcggttctg caatggacgc agctaaggga atgtggatgt tctatgaaca cccagacaca
     7921 tctttctttg gtgcaaaaca aaaattcttg gatatccgta aacggacata taagatcgac
     7981 aaaccagaaa aaacacaatt cgtatgtatc ccgacaacat cagggactgg ttctgaagta
     8041 acgccatttg cggtcatcac tgacagtgaa acacatgtga aatatccgtt agcagattat
     8101 gcattgacgc cagatgtcgc aatcgtcgat cctcaattcg tcatgtcagt tccagcatct
     8161 gtcacagcag ataccgggat ggatgtgtta acacatgcaa tcgaatccta tgtttcagtc
     8221 atggcttcag attatacacg tggattgagc ctacaagcaa tcaagttagt ctttgactat
     8281 ttagaaaaat cagtaaaaac acctgatatg gaatcacgtg aaaaaatgca caacgcttct
     8341 acaatggctg gtatggcgtt tgctaacgca ttcctaggta tttgtcactc agtcgcacat
     8401 aaaatcggcg gggaatacgg gatccctcat ggacggacaa atgcgattct tttaccgcat
     8461 attatccgct ataatgcaaa agatccacaa aaacatgcga tgttccctaa atatgactat
     8521 ttccgtgcag atacagatta cgcagatatc gcaaaattct taggtctgaa aggcgaaaca
     8581 acagaggaat tagtcgaagc tttagcaacg gctgtttatg aattaggaaa atctgtcggc
     8641 atcaacatga gtctaaaagc tcaaggagtc acacaagaaa cactagatac aaccgtagac
     8701 cgtatggctg aattagctta cgaagaccaa tgtacgacag ctaatccgaa agaaccattg
     8761 atctctgaat tgaaacagat catcattgat gcttacaacg gataagcaaa agaaagcgta
     8821 gaaaaaagat aagaaaatag atgaaaaaga acttggaaaa cgttgtttct ccaagttctt
     8881 tttttaattt ccaagtaact gaaagttact tttgttattt aacatttagg tcaattttag
     8941 acagtttttg ttcaaaaagc gatatttata gtggacggta ttactgctat attaaggata
     9001 taaaatgaaa gcgtttaaaa aggtggcgta aagatgatta ttaaagaaga gatttttgta
     9061 cctaaagaat tagtgaaaga aaaaattgac ctgctcgttg aaaacctgac aacgatcaaa
     9121 gacgataatg gtgaattttt gttggacttt gatggactga aagtagatga caaaagctgg
     9181 acagtgtgga attggccaca aggtgtcggt ctatatggta tttataaaaa ttaccagatg
     9241 acaaaaaatc ctcgcgctta tcaagtggtc aatgaatggt ttgaggatcg tatggaagaa
     9301 ggcgctccgc ccaaaaacgt caatacaatg gcaccgctat tgactatggc ttacttgtat
     9361 gaagacacga aagattcacg ctatttgcct tatttagaac aatgggcaga atgggtcatg
     9421 aatgacatgc ctcggacaaa tgaagacggg ttacagcatg ccacatatgg accggaaaat
     9481 aagaatcagt tgtgggacga tacattgatg atgacagtgc ttcctttggc aaaaatcggg
     9541 aaactgttga atcgcccaga atatttagaa gaagctcgtt accagtttat gatccatatc
     9601 aaatacttga tggataaacg aacaggattg tggtatcacg gctggacgtt tgaaggaaat
     9661 cataactatg ccgaagcatt ttgggctcgt ggaaactgct ggttgacgat tgctattcca
     9721 gagatcattg aaatcttaga attatcgaaa gaagatgcat tgcgcaaatt attgatcgaa
     9781 acacttgaag cacaagtgcg tgcattaaaa acttatcagt ctgaaagcgg tttatggcat
     9841 acgttgttgg atgatccttc ttcttacgta gaatcttctg caactgcagg atttgcttac
     9901 ggtattttga aagcggtcca taaacgttat ttaccacaag aatataaaga agtcgcttat
     9961 cgtgctatcc aaggattgct tgaacaaatc gatgaaaaag gagaagttca aaacgtttca
    10021 atcgggacag gaatggggga cagtttagat ttttatcgga atatcggaat cacagcaatg
    10081 ccttatggac agtcgttaac ggtgctttgt ttgacagaat tgctcgtctc ttattgttaa
    10141 aagaaaggaa acccatatga aaaaaacatc actgctgttt gcagcaagtt cgcttagcct
    10201 aggtctgcta ggtctaagcg gctgcggaaa taattctagt gtggcaactg tcgcagatgc
    10261 agatgtaaat gagatagtta ccttgcgctt tgcttatgca agcaacagcc agccagtaat
    10321 tgatgcaatg aatgaatttg ggcgtttagt aaaagaaaaa acagatggtt ccgtacagat
    10381 ccagtatttc ccagatggac aactgggtgg agaacgtgaa ctgatcgaat tgacacagtc
    10441 aggagcagta gatttcacaa aagtaagtgc ctcagcgttg gaaagtttct ctaaagatta
    10501 ttcgattttt tcagttcctt atctattcaa tgatgaagaa catttcttta aggtgatgga
    10561 taatgaagaa ataatggagc caatctacca atcgaccaaa aatttaggat ttaccggatt
    10621 gacctattat gattctggtc agcgcagctt ttatatggta gacggtccga tccatacgcc
    10681 ggaagatttg gagggaaaga agatccgtgt gatgcaaagc gaaaccgcta tcaaaatggt
    10741 agagctttta ggcggttcgc ccgtacctat gggaagtgat gaagtgtaca cgtctcttca
    10801 atccaatttg atcaacggat cagaaaacaa tgaatttgtc ttgtatacag ctggacatgg
    10861 tggtgtggct aaatactatt cctatgatga gcatacacgt gtgccagata tcatcatcat
    10921 gaatgatgcc atcaaagaac agctaactga tgagcaggaa aaagccattg aagaagcagc
    10981 gaaagaatca acggtttttg aaattgaagc ttttgcaaaa gcaattgaag aagaaaaagc
    11041 tttagcacaa gaagaacatg gagtccaatt caatgatgta gataatacac cgtttcgaga
    11101 ggcagttgcc ccacttcatg atatattcaa aaacgatcct acctacaaag acctttatca
    11161 aaagatccaa gagcaaggag cgtagctgtg atgaaaatga ttttaaacaa ggtattagag
    11221 atcctgggag ctgttttgct tgttgggatg gtcgctgttg ttttatggca agtattttcc
    11281 agaacggttt taggaaatcc aaatacggtc acggaagagc ttgttcgatt cggtcttgtc
    11341 tggtttgcca tgttgtcttc cgcgtatgtt gtgggacaaa aagcacattt agccgtaacg
    11401 gttttaagtg aaaaattaac tggcaaaaaa agtaaaattt tagaagttgt tgttcaaagt
    11461 ttatttctgg tatttgctgc gatgatcatg gtgtatggcg gatggaatgc tgtcacattg
    11521 acaatggggc agatctcgcc ttctttaagt attcctatgg gatatgttta tctgtcagta
    11581 cctgtatcgg gggtactcat cattatctat agcctgatca atctaatcga tacattaagc
    11641 aacaagccag caattcaaga aaaaatataa aaatggagga ataaaatggc aatagaagcc
    11701 ggattagtgt tattttttgt atttgttgtg ttgcttgtat tagggatgcc gattgctata
    11761 agtattgcat tctcatcgat gatgacttta ttgttagtta taccgtttga tgtttctgct
    11821 tttagttcag ctcaaaaaat ggtgggaagt atcaatagtt tttcgctgat cgctattccg
    11881 tttttcgttc tctcgggcat tatcatgaat aatggaggga tagctaagaa actagtggat
    11941 tttgcgatgt tgttcgtcgg gcgcgtgccg ggggctttgg ctcatacgaa tgtgttaggg
    12001 aatgctttat ttggttccat ctctagctcg gccattgccg cttctaccgc gattggcgga
    12061 gtgttgatcc ctcagcaagt ggaagaagga tatgaccgga agtttgcgac agcggtcaat
    12121 atcgcgtcag ctccgacagg tatggtcatt cctccaagta ctgcttttat catgtattca
    12181 cttgttgctg gtggtgcttc gatctctgct ttgtttatgg gaggttatct cgtaggcgct
    12241 ttgtgggcgc taggaatcat gctagtagca ttcatcgttg ctaaaaagaa taaataccct
    12301 gttgtcgaaa aaggacagat ggctcatgct ggaaaaataa taaaagaggc gattcctagc
    12361 cttctattga ttgtcatcat tatcggtggt atcttgacgg ggatatttac agcagtagaa
    12421 gcttcagcga tagctgtcat ttactccctg ttgattgcta tgttttacta taaaacggta
    12481 aaactaaaag atatacctaa tatgttgttt caatcagtag caatgtcagg gacgatcatg
    12541 ttcttattgg ctacttcttc catgatgtct ttcgccatgg cgtttaccgg tattcctcag
    12601 gcaattagtt cgttgattat gggcgtaacg gataataaat ttattattct gttattagtc
    12661 aatcttgtgt tattactggt gggtatgttt atggatgtgg cgcctgctat cttgattttt
    12721 acaccaatat ttttaccaat cgtcacaagt gtaggggttg atcctgtaca ttacgggttg
    12781 ttttcaatca tgaatctgtg tgtaggctcc atcacgccgc cagtaggtac aggactatat
    12841 gtcggtgcaa gtgtaggagg cgtaaaagca gaggcaatgc tgaaaccgct tcttcctttt
    12901 tatggggtta tcttagtcgt cttgtttttg attacttact tcccgcaaat cgtcatgtgg
    12961 ctacccaata tgctgagtta ggagaatagt tatgttgaac attacaatta gaggacatga
    13021 tctttccgaa gtccaaacga tagaagatct tgcagaaaaa acaaaagaac aagggattca
    13081 tacactgcag ctcgccttag gtctttcgtt tcctgaaaca ccttctggcg caaatgagat
    13141 caattctggg atgggaaatt atgtcaaacg agttttagaa aagcaagaag tgaccgtagg
    13201 aattttaagt tgctatatca atatgattca tccagattta acgatacgac aagagttgct
    13261 gacaaagttc gagcagtatc ttcgctatgc ttcttccttt ggtgcgtcga tggttgcttc
    13321 ggaaactgga tgtgttttgc cggaaatcca atatacggaa gaaaatttca cagatgaagc
    13381 atttgctgaa gctgtgtccg ttatccgtcg cttggtaaaa gctggagaaa aataccaaat
    13441 gatggtgggg atagaaccag gtttgaatca tccggtgtat tctttagcaa gggtagagca
    13501 gctgatccaa gcagtagatt cggactatct aggaatcatt ttagatccga ccaatttgat
    13561 cacaagtagt gattatcaag aacaagtcca attggtagaa gaagcttttg aacgttttgg
    13621 tgaaaagata tgtgcggttc atttgaaaga ttttcgtgtc gaacaggaaa aaatcgtgcc
    13681 ggtaaatttg ggagacggtg tgatcgagta cacaaaaatc aaagaaatca tcatgaagaa
    13741 tcgtccgtac ctgtatgtgg ttcttgaaga aacaaaagat gatgggattc gttatggaag
    13801 aagtcttctt gaataatgta aagaagacgt tggttaacta atatttagaa tggagggggc
    13861 ggggctagaa gatgccacgt ctcttctttt ttataagagt atataaaagc agctcttttt
    13921 gattacaaaa aacgtggtat aataaaattg tgcataagtg aacaaaagga ggtgcggcac
    13981 atgctccaaa agaaaatcag cggtgaacaa gtcaatacga tggtttctga tcagtatgaa
    14041 atctatcatg tcaaagatgt cgtcagccaa aataaaacga tctatcatca tcatgatttc
    14101 tatgagatcc atgctacatt aaagggagaa gcgacttttt atttgaacgg acgacaattt
    14161 acgatcaaag caggaagtgt gctgctcatc cattccaatg atttgcatcg tatcgtccgc
    14221 caatcttcag atgtattcga gcgtgtctat atctttgtca ccccttcttt tctagaaagt
    14281 cgttccacgc catggtctaa tctatcggct tgttttcaac caatgggaga gaagaggagt
    14341 cgtgtattgc aaatagaaca ggaagtattg aagcaaaaat tatcatttat cgaccatcct
    14401 cctgataaaa aaatttacgg tgaagacata aaatatgaac aagctctggt agaatacttg
    14461 atttttctca atcaagttgt acaaaaagaa gagagtgcgc aagaacagaa tgctgtagtt
    14521 cctaatgagc gtgtggaaca aatgttacaa tatatctcaa aaaatttatc tcatccgctt
    14581 tctttagagg aaatggaaaa gcagtttttt gtcagcaaat accatatcac acgagaattt
    14641 aaaaagtaca ctggatttac gtttcatcag tatgtaatga agaaaaagct gatctatgcc
    14701 aagcacttgt tgcgagaata ccgcagctct agtgctgtat atagtaaaag tggtttttct
    14761 tcttatccgc attttctgaa agcattcaag agagagttcg gcataacgcc taaagaattt
    14821 ttgaaacgtg atacacagaa acagttggtt cattatgaac attttgaaga tgaacaatga
    14881 gaatgatcac taaaaaataa ccgcagtagc tgctgttgtt tacatagaag cagaaactgc
    14941 ggttatttta tttttatcta tatatttcaa aatattttga aaaaatgacg tacatattat
    15001 atgaatcagc tgaatttacg aaagtctctc ggcgatagtc ctgtttttgc tttgaacagg
    15061 cggctaaagt aagcaaaatt ctcaatccct atttcttcgg aaatcattcg aaccgtaaat
    15121 tctgtatacc gaagaaggtc tttagcgtaa gaaagttttt tgctgatcaa ataatcgatt
    15181 ggtggagaac cgataaattt ggaaaaatct ttgctcagct gatatttatt caataagaat
    15241 tgttgttcta attgatcaag tgtaatcgtt tctttgaaat gttcgtctaa gtattgcttc
    15301 agtttgtaaa cgtaggcggg aatatcctct tcttcgaaat ctagctgata cttttgcaaa
    15361 atcagttcat tcagcaactc gtggatagct acagaggact ggaaatcggt acgggcattc
    15421 gtgccttgtt gcatgtggat caattctgtg atcaaatggt ggatcttgtt ttctgatgga
    15481 tcccctgttg aatggaaggt gttatggccg tcttttgtga actcctgata aaatgattgg
    15541 acgttctgac cattcaaatg gatccaatcc atttcccatg gttcttcgct gatcgtttga
    15601 taacgctgat attcttggca gtcaataaaa aataagtctc cagcttttag ctgttgctga
    15661 ttatcattat atgtaagcga acctttgcca gacaaagtaa actttatcaa gtaagaaggt
    15721 aaatgtgctc gttcagtata gtaagggatt ggtgctttga agtaaccgat ttcttggata
    15781 taaaaaaata aattcctgct tctttgtgta ggcgtcaaga tcactctttt tgagtcttcc
    15841 gaccatgagt ggttggcttt ttcccagtaa tccatgtaaa cactcccaac ttgtcaagat
    15901 aatgcaatta tataccaaaa tagtgtgaag caaaatataa gattctgtat tatgatagca
    15961 ttgttaataa atgataacgc tttattaata aagtgctaat caacaataaa gtaaaagagg
    16021 tggagaaatg aatccaacat ttgttgccat cgatatcggt gcatcaagcg gacgactaat
    16081 gaaaagtacg agggatgcaa aaggttcttt gatcttggaa gaagtacacc ggttcaaaaa
    16141 cggctttcgg aacaaagacg gtcacgatcg ctggaagatc gattatctta tcaaagagat
    16201 tttgattgga tttgaaaaat taaagcagac agggattgat cgcctttttg cggggatcga
    16261 tacatgggca gtcgattact gtctgattga tgaacaaggg gatcggataa atgatccgat
    16321 tgcttatcgg gacaagcgta ccaatggagc agtagaacag ttttctgaaa tctattctct
    16381 agataagttg tatgagcaga cagggattca gatccagcct ttcaatacct tgttccaatt
    16441 gtttgctgaa gaaaaagaaa atttggcaaa agcacataaa ttgttactga tacctgatta
    16501 tttagggtat gtctttactg gtaacatggt gacggagaaa actaatgcat ctactatgca
    16561 gctgctgaat gcagggacaa aagaatggga aatagaactt cttgaaaaaa tcggtgtctc
    16621 gaaggaatta tttccaccat tgacagagcc gggaacgata ctaggagatc tgcaaaaaga
    16681 acaattttca aaatatgatt tgccagatgt gacctttatc acagtagcaa gtcatgatac
    16741 ggcgtcagct gtattaggaa cgccaggtca aggagaacgt tggggttata tcagcagtgg
    16801 gacatggtcg cttttaggga ttgaaacaaa gatcgccaat gtttctcgca atgctttttc
    16861 tgaaaattat acgaatgaat ggggtgccca taacacggtg cgttttttga aaaacatcat
    16921 ggggatgtgg ttgatccagg aagttgcccg aatgcaagag tacgagtaca gttatgcgga
    16981 attggcagag cttgctgcaa aagaaaaacc gctgcagcaa gtgatggaaa tcaatgaccc
    17041 tcgatttttg aatcccccaa atatgataga agagattcag caatactgtt ttgaaacaga
    17101 gcagccagtc cctgtctcat cgggagctat cgctcgttgt gtgtatgata atcttgctct
    17161 ttgttacgca caagagctga tcaaagtaga acacttaact ggaacgaaat tggaaaagct
    17221 gcacatcgta gggggcggat cgaataatcg tctactgaat caattgacag cagattatgc
    17281 cggaatcatt gtagaagcag gacctagtga agccacagca atcgggaatg ttgccatgca
    17341 aatgctcagt acaggtcagt tttcgaatat agaacaagca agaaatgtaa tcaaacagtc
    17401 gtttccatgt gaaacttttt acccagatga aaataagcaa aacacgatgg aatggtacgt
    17461 gaataaaatc aaaggagtaa tcgtatgaac acgattgaaa gaaattacga acaagcaaaa
    17521 gaaaaatatg caactatcgg tgtagataca gatgctgtac tagaaaagat acaggacatc
    17581 aaaatttcta tgcattgctg gcaaggagat gatgtcaaag gtttcttgac accggatggc
    17641 gaattgaccg gtggaatcat ggcgacaggg aattttccag gagccgcacg aacacctgaa
    17701 gagcttagac aagatctgga gaaggcttat tcgttgatac cgggcaaaca caaattgaac
    17761 cttcatgcta tctatttgga tacagaagaa tctgtcgatc taaatgaaat tgagccgaaa
    17821 cattttgaaa aatgggtaga gtgggcaaaa aaagaagaaa tcggtcttga cttcaatccg
    17881 actttctttt cgcatccaat gatgaaagac ggctttacat tggctcatcc agataaagaa
    17941 gttcgtgaat actggatcga acacgggaaa agaagccgca aaatcgcgga gtactttggg
    18001 aaagaaactg ggcaaacaag tatcaataac ttttgggtac ctgatgggat gaaagataat
    18061 ccgattgatc gttttacccc acgggaacgt ttaatggaat cactcgatga aatttttaca
    18121 gaagagttag atgaacggta tgtacaagat gcagtagaaa gcaaactatt tggtttaggc
    18181 gctgaagctt atacagtcgg ttcccatgaa ttttatatgg gttacgggtt gactcgtgac
    18241 aaacttgttt gtctagatgc tggacatttt catccaacag aagtgatttc caataaatta
    18301 tcttcattag ctttattcag caaaggaatc atgttgcatg tttcccgtcc agtgcgttgg
    18361 gattcagacc atgtggtttt gatggatgat gaattgcagg aaatcgctaa agaattagtc
    18421 cgtaacgaat tgttggaaaa aacaaatatc ggtctggatt tctttgatgc aacgatcaac
    18481 cgtatcgctg cttgggtcat cggtacgaga aatacacaaa aagcactgct gaaagctatg
    18541 ctggaaccag ttgagcgatt gaaagaaatg gagctggctt ttgactttac ttcaagaatg
    18601 gcttatacgg aagaattgaa agatttcccg tatgccgatg tatggaatta tttctgttac
    18661 aaaaatcaag ttccagttgg tttggattgg ctggaagaag tccaggaata tcaaaaagac
    18721 gtgttggaat taagaaaata ggagtgtggc tatattgaaa aaaatagata ttttacaagc
    18781 gccttatgtg aaagaaatga tcgaaacgac gtcgaatctt tatcgcttgg gatgggatga
    18841 aagaaatggc gggaatattt cttatttact aaaagaagaa gagatcacac cgttcttgga
    18901 tcctgaaaaa gtgatccgcc gcatctcgat gatttttgat gccagccgtt tagcaggatg
    18961 ctattttatt gtaactggtt caggaagata ttttaaaaat gtagcgagcg aacctgccga
    19021 gaatcttgga atcgttcgag ttgctgaaga tggcaaaaca ctggaacttt tgtgggggct
    19081 ggaaaacgaa tgccttccta caagcgagtt gccaagtcat ttcatgagtc atatcgcccg
    19141 tttagaagta gacccagata atcggatcgt tatgcattgc catgctagtc atctattagc
    19201 gatgagtttt acgcatgaat tagacgaacg ttcctttagt cgtacgctat ggcaaatgtg
    19261 tacggaatgc ttagttgttt ttccagaagg aatttccatc attccgtgga tggttccggg
    19321 aacaaatgag attggggaag caacagctga aaaaatgaaa gaaactcgat tggttttatg
    19381 gccacaacat ggaatctacg ggtcaggaaa agacatggat gaagtctttg gtttgatcga
    19441 gacagcagaa aaggcagcag aagtctatac gtacgtcaaa gcgcaaggac caatcttgca
    19501 aacaatcacg gacgaaaacc tgtggcattt agcagatgcg tttggtgtca ctccaaaagc
    19561 aggttatttg gaggaagttc atacgaaagc aggtgtctga catggtgaaa aaagcttttt
    19621 gcatgaaagt ttacccagaa aaacaagaag aatacaaaaa aagacatgat gaactttggc
    19681 cagaaatgcg tacagcactt cgtgaacacg gggtcatcga ctattcgatc tatcttgatc
    19741 cgagtacaag tttgttattt ggttacttag tgatcgaaga tgaaaagtta tgggaaaaaa
    19801 tggcaaatac atctatcaat caaaaatggt ggaagtacat ggaagatatc atggagacaa
    19861 atccagatgc ctctccagtc agttgggaat tgatgccagt ctttgaactg tagcaacaag
    19921 caactgggca accggttgct tggggttctt tcgtttttat tgtgaaaaaa aatacaaatt
    19981 aggaggaata gaaaatgagt aatcgaatga ttttaaatga aacatcgtat tttggaaaag
    20041 gagcgattga gtcgatcgtc cctgaatttc agcagcgagg attcggcaaa gcagctgtca
    20101 ttactgacaa aggattgatc gagcacggta tagcaacaaa agtaacagaa cttctagata
    20161 aagcagcaat cgcttatgct ttatacgacg ggatcgtacc taatccaacg atccaaaatg
    20221 taaaagatgg agtggctttt gttaaagagg cagaggcaga ctgtttgatc gcaatcggtg
    20281 gaggttcgcc aatcgatacg gcaaaagcca ttgggattat tttgacgaat ccagagtttt
    20341 cagacgtcat tagtttagaa ggtgttgctg atacgaaaaa tccatgttta cctatattag
    20401 ctataccaac gacttctgga acagcagcag aagtaacgat caactacgtc atcacagatg
    20461 aagtaaatca ccgaaaattt gtttgtgttg atcctcatga tatcccaatc gtcgcgttca
    20521 tcgacagcga tatgatgatg ggaatgccga aaaaattggc tgcatcaaca ggtatggatg
    20581 ctatgacgca tgctattgaa gggtttatca caaaaggcgc ttgggaaatg actgatatgc
    20641 tgcatttaaa agcaatcgaa atcatcggcc attctttgga agtttctgta gatggcgatc
    20701 aaaatgggcg agaaaaaatg gcattaggac agtatattgc gggaatgggc ttctcaaatg
    20761 tcggtttagg actggtacac gggatggctc acccgttaag tgcatggtac aacattcctc
    20821 atggcgtagc gtgtgcagca cttttgccaa ctgtcatgaa atataacaaa gaatatactg
    20881 gagaaaagta ccgtgagatc gctcttgttc tagggattaa aggagcagct gaaatgtctt
    20941 tagaagatgt aagagaagcg gcttgtggtg agatcgatcg gttgagcaaa gcggttggaa
    21001 tcccagaaac catttctgaa ttaggtgtaa aagaagcaga tattccagca attgcagaag
    21061 atgctttgcg agatgtatgc acaccaggaa atccaagaga aacgacagta gaagaaatca
    21121 ttgctttata tcaaagtttg atgtaaaaac gaagcggatc ttcaacatta aattgcctgt
    21181 aaagagaaat ggtagtttat atctggatat ctcttttaaa ttgatggtat ttccgctata
    21241 atttttctta taaagaaata ggagaatatt atatggaaaa taaaaagcct tatggaactg
    21301 tattgatcaa agcctctaaa atactagact atttagcgga aaaccaagat gtctctttgc
    21361 agacgatcgc aaagggtgtg ggaatgacct cttctacagt cttgaaaata ctagatactt
    21421 tgttgatgat cggctacgta aataaaaatt cagagaaaaa ctatcgttta ggtgcaaagc
    21481 ttattcgcta cgcgaataaa aacattgaac aaatcgattt ggtagagttg actttaccgt
    21541 ttttagaaca gctgcagcaa aagatcgatg agactatcca cttaggggta ttggacaaca
    21601 atgagatctt gtacgtgaac aaactagatc caaaacatca aacgatccgc atgtcttcaa
    21661 aaatcggaat cacccgacca ttatacaatt ctgcgatggg caaagccgta ttagcagaat
    21721 tcagtgaaga gcagtacact gattatcttg aaaagcatcc gttgatccct tacacagaat
    21781 atacgatcac caatgcatta cggttgaaaa aggaaatcca aacggtaaaa gaaacccaca
    21841 tcgcatttga cgatgaagaa atcgaacgtg atattttttg tataggagcc tcaatcgtga
    21901 aaaacgaaca aatcattggt gcatttagtg taagtatgcc gaaatatcgt ttaacagatg
    21961 agacaaaaga acaaataatc agtgccctca agcaaacaaa aagcgaaatc gagcaaagaa
    22021 ttcaaaaata atgaaaaaag cgtttgcaat ttttcttttc tgccgtataa tatgggtata
    22081 gatttccaag ttataaaata aaatttctaa ataggaaata ggtggagaag atgaaaaaaa
    22141 ttgatatttt atctcgattg aaaaacgccg gagtgattgc ggtggtacgc ggaaaaagca
    22201 aagaagaagc tttgaatgct tgccacgcaa tcatcaaagg tggtctaact ggtattgagt
    22261 tgacttttac agtccctcaa gcagatcaag taatcaaaga acttttgtca ttctacaaag
    22321 accaaccaga aatagtgatt ggcgcaggca cagtattaga cgctgtcaca gctcgcttgg
    22381 ctatcttagc tggcgcagag tatattgtta gcccttcctt tgatcaagaa acggcagaga
    22441 tgtgcaatct gtatcaaatt ccttacttac caggatgtat gactattacc gagatcaaaa
    22501 cagcgctgaa aagcggggta gatatcgtca aactatttcc tggaagcgct tatggaccaa
    22561 gtatcatttc tgccttcaag gcgccgatgc ctcaagtcaa tatcatgcca actggcggtg
    22621 tgagtctgga caatatgaaa gagtggttcg atgctggtgt cgtaacagtc ggagtaggtg
    22681 ggaacctttt agcacccgca gctacaggag attttgacaa agtaacggaa gtcgcgcaac
    22741 agtatgcagc aaaaatgaaa gaaatcaaga ggtagctgct tatgggaaaa gtagtgacac
    22801 tcggagaaat catgttgcga ttgtccacag agcagggaac ccgtatcgat tcaagtgaac
    22861 gattcgctgc ccattatggc ggaggggaag caaacgtagc aatttcttta gctaattacg
    22921 gacatgaagc gatttttgct acaaaagtac ctgataacgc attgggaaaa gcagtcaaaa
    22981 agcacttgca atgttatgga gtagatacga aacaggtatt atctggtgga tcaagactag
    23041 gtacttatta tatggaaact ggtagtggcg aacgcgccgc ctcagtgatc tatgatcgtg
    23101 ccggatcaag ttttgctgaa atggatcatt tggaatggtc gctagaggag ttattccaag
    23161 gaatagatat atttcatgtt tcaggaatca ccccagcttt gtctaaaaaa tggcaaaaaa
    23221 tgacgaaaca ggtgatagaa gctgcaaaaa aagctggctg cctgatcagc ttcgatatca
    23281 actatcgtgg aaaattatgg acacagcaag aagccagcga agtaatccat cagcttttac
    23341 ctttagtaga tatctgctca gctggaaaaa tggatgctct ttatttgtta ggtatcgaga
    23401 aagcgccaga agcagaagaa caacctctaa tttattatta tcaaaaaatg caggaaaagt
    23461 tcccgaatat tcaggtgttt tattcgacca agcgtaccgt tcattcagca agtgaaaatg
    23521 aattgaaggg gacattgtgg atgaaccatg aatatgtgga atcccaagtc catagaatca
    23581 ccccaatcgt ggatcgagta ggtggcggag atgcttttgc aggtggcgtg ctccatggga
    23641 ttttatccaa tatgtctccg caagaaatca ttgattttgc tacggcagct tctgccttga
    23701 agcatacgat ccatggggac tgcaaccaat ttagtcaaga agaagtcgca caatttttag
    23761 catgcggctc tggaaaaatc attcgataga aggagtagaa gaaaatgcaa gaaatggaaa
    23821 cacgttatac acacagtcca gaagatatcc gtcattattc aacggaacaa ttgagaaaag
    23881 aatttttagt agaaaaggta tttgaaccag ggaaaatcag tttgacttat acgcacaacg
    23941 atcgaatgat ctttggtgga gtgacaccta ctgaaaaaga attagaaatc acattagaca
    24001 aagaactagg tgttgattac ttcttagagc gtcgtgaact aggtgtgatc aatatcggtg
    24061 gaccaggatt catcgagatc gatgggcaaa aagaagaaat gaaaaaacaa gacggatact
    24121 atatcggaaa agaaacacga catgttgtat tttcttctca agatgctgaa aacccagcta
    24181 aattctatat tagttctgtt ccagctcatc ataaatatcc aaatgtaaaa atcagtatcg
    24241 accaagtaaa accaatggag actggtgaag gcctgacact gaatgaacgt aaaatctacc
    24301 aatacatcca tccaaatgta tgcgaaagct gtcaattaca aatgggttat acgattttag
    24361 aaccaggaag cgcttggaat acgatgcctt gtcatacaca tgaacgtcgt atggaagctt
    24421 atgtctactt tgattatgcc aatgaagata cacgtgtgtt ccacatgatg ggcaaaccag
    24481 atgaaacaaa acatttagtt gtagacaatg aacaagccat tatttcgcca agctggtcga
    24541 tccattcagg tgtaggtaca agcaattact cattcatctg ggcaatgtgc ggagaaaata
    24601 tcacctatac agacatggat atggtgcaaa tggatcaatt aaaataagca taagggagag
    24661 aaaatgatgg aatttagtat ggatatgttt cgtttagatg gaaaagtagc attagtcacc
    24721 ggtgctgtct atggtattgg atttgagatt gcacgctctt tagctacagc aggagcaaaa
    24781 atcgtattta ataacttgaa tcaagaatca gttgatgaag gtatagcgca ttataaagaa
    24841 gcaggcatcg atgcaaaagg ttatgtctgc gatgtgaccg atgaagaagc ggttcaagcg
    24901 atggttcaac agatcaaaga agatgtaggt tcagttgata ttctagtcaa caatgcaggg
    24961 atcatcaaac ggacaccgat gatcgaaatg gatgcggcag acttccgcca agtaatcgac
    25021 gtggatttaa atgccccatt catcgtttca aaagcagtta ttccggatat gatcgaaaaa
    25081 ggcggcggta aaatcatcaa tatctgctcc atgatgagtg aattaggacg cgaaacggtc
    25141 agtgcttatg ctgcggcaaa aggcggatta aaaatgctga cgaaaaacat cgcttctgaa
    25201 tacggtcaat acaatatcca atgtaatgga attggaccag gttatattgc tacaccgcaa
    25261 actgctccat tacgcgaaac acaagaaaac ggtgaacgtc atccattcga tcaatttatc
    25321 gttggacgta cgccagcagc acgctggggc gagccaatcg atttggctgg accatctgtc
    25381 ttcttggctt ctagcgcatc tgatttcgtt aacggccatg tcttgtatgt ggacggaggc
    25441 atacttgcct atatcggaaa acaaccttaa aagagcttta gtacactgtt tagtggagag
    25501 gttgtgaaat cagcggattg aacgaatacc gaaggacagc tgattaaaca tcatttattc
    25561 gaaaaaagag gctgggacag aagcatttaa ctccaagaaa taagaaggaa ttcacgaaaa
    25621 ttgcttttca aatttttgtg aatttcagct tatttccgaa ggagttgctt ttacttccgc
    25681 cgtttgtacg tgtttagagc gtgagacaaa agtgttcttt acttttgtcc cacgctcttt
    25741 tctgtgcgtc ttccatactt cactaagtcg atccctcttg cttcgcacca atccttcact
    25801 ggtccggaaa agatcagaga ttgttggtgt agggccgcgg tattcgttgc gccgaccata
    25861 gtataaagca gacgaagctc ttcttgccat tgcttcatca gtataatagt ttcttctacg
    25921 ccgtgattca tcagatgcgt cagtacggtt cctgaagtac ccacggcatt tgcgccgaga
    25981 caaagggctt taaatatgtc ataggcattg cggatacctc cggaggctag gatttccata
    26041 gaagtgtctg cttcatttgc ttcaagcaat gaagagactg tcgattgccc ccagtcagct
    26101 aaataactca gttcccgctt ggagcgacgg gcgttttcga tctgggtgaa gcttgttccg
    26161 cttcgaccgc tgatatcaac tgtatgaact cctaaagcag ctagatcatt gagcgtttct
    26221 cttgtcatgc caaaaccgac ttcttttacg atgaggggga cgtcaatggc tgtttgagtt
    26281 tcttgaataa gtactttcca attggtaaaa tcacggtctc cctcaggcat aaccaactct
    26341 tgaggtgcat tcaaatgaat ctgtaaggca tctgcgtgaa acaatcggat agcttctttg
    26401 gctctttcga cagaagtccc tgcaccgatg ttggcaatga ttttcccgtg aggatattct
    26461 tgtcgcataa tcgtataagt atcggctaaa gaagggactt tcaaggcagc gctgactgaa
    26521 ccagtggcaa tcatcaaatc tgcttctctt gcgacgattg caagatcttg gttgattttt
    26581 tttgtttttt cgcttccgcc agtcatcgca ttgatataaa atgggctgct tagtgtaaac
    26641 ccaactgcct gtgtacttag atcgacatca gaaactgcta tttgcggcaa agggttatgg
    26701 atgatccgta cgaagtcaaa ttcgtttttt tgtttatcat gaaaggcttt agctagtgaa
    26761 acatgttcgt cttttcgatt catcggtttt cctttctttg atcgctatag acatgtaacg
    26821 gcagtggagt gatttctgct ttttcccatg cactcattaa aggaagaatg ccagatttct
    26881 ggtcaacaat tacgattccg caatcgcccc cacctgcacc agaagatttt gcggctcctt
    26941 catactgttc agctaaatta cacaatttgt tcaaagcagg cgtttcgatg acgaccccag
    27001 tgattgcaga taaatcatgc agtaattgtc ggttttttcg aatcatctgt tggatcaacg
    27061 ttacattatt ttctttaaac cctttgatca tttcgttgac acattctgta ctatttttta
    27121 agaaaagctg ataagccacc attttatctt ctctcgaacg gtgaacttga tcgaccaaat
    27181 cagaagtaga ggcagggcta cccgtccaac caatcaataa acgtaaatct tcaggagcaa
    27241 tcaatggctc aatggataga cctggccaat ccagggcaag taactcactg atagaatgct
    27301 gagtttcttg ttcttggagc caaggatggt cgaaggttga gaaagcgatc cagccaccat
    27361 aacagctagc agcgatgtcg ccgcaggaac cattatcttg aactgctaaa ttggctagtg
    27421 ctgcaatctt gaaaatctcc aactgagata aattcaacgc gtaaaaaaca ttcaaggctt
    27481 tgaccgttgc aacggtcacg gcaccgctag aacccaatcc atatttccgg ccatttgaac
    27541 tgtctaactc acttgttact ttcagatcat aaaaggataa aagaatgttt ttttcttgtg
    27601 catacttttc agtcaagcga atagcagcaa ggatataatg aaaaggattt tcccgaatat
    27661 ctaaaactaa ttctccgttg cgtcttgtcc aacgtacagg catcccacta tattgtgcag
    27721 attggatact tccgactttt cgtgcagatt ctacagtgac tgtcacgaat tgatcgactg
    27781 cagcgataac tgctggatgg cctgtttcaa caactgcata ttctccggca atatagagtt
    27841 tgcctggtgc agatacttca atcataaaaa tctcccttta ttcaataatc gcaattcctg
    27901 gaccagcatg tgcagtaatt acttgttctt tgctaaataa tttggtaaat gtttcttgta
    27961 cctcagataa atggctgttt tccactaaaa ctttgacatt agggccagca tccatcgtaa
    28021 agtagcatgg aatgccttgc tttctcaatt gtcgcaccgc atccatcgct tttaagctgt
    28081 caggagacca gtaagtgaat ggaggctggg cagctaaagt cgttccatgc atttttagtc
    28141 cgtttctttc catcgtttct ccgagaagtt ggaaatcttt tgttttgatt gcttgtttca
    28201 attgatatag atccccttca acggaatcta accagccttg ataaaaactg gatgtttcga
    28261 ctgtccgacg catcccattt ctgctggaca cttctttttt ctggtcgttg atcaaaacga
    28321 aaaccattgc taaatcgtct tcgaaagaat cggaagggac tggcttagcg taagaactta
    28381 agtcgtcatg gcctttttcc cattcgacga aaccaccgaa aatacttcgg caagctgaac
    28441 cagacccgcg tcgagcaaat cttgaaagag agagatcatc taatccaagc ttaagagcag
    28501 tattgcaagc gcctgctaaa gcagctagcc cgctggcaga ggaggctaat ccagctgcgg
    28561 taggaacgaa attctgactg attactgaag cttttagtga gaggccggct tctttacgaa
    28621 aaaggtcaag aaactgactg actttttttg ttgctttttc gtcttgcaag gtgccatcta
    28681 gataaaattc atctaccata tagctatcag aaaagatgac ttctgtctct gtataaaatg
    28741 catccaatgt taacgaaagg ctgttgttca ttggaaggat gagttcttca tttttcttac
    28801 cccaatattt gattagagca atgttggtat atgcgcgtgc tttgccttta aacataggta
    28861 tgtactccta atccttgtat ccaagtttca gcagcacccg catcttcaag tgcttgactg
    28921 atttcttggg cttttgtttt tgtttgtgct aatgcaatca tacagccacc gcgtccaccg
    28981 ccagttaatt tggcacccaa tgccccggta tcttttgctg tttggatcaa tagattaaga
    29041 aaatcattgc tgattgtcag cttttccaga agtgattgtg attcatccat tgtctgtgcc
    29101 aacgtttctg gtgaattttc aatgattgct tgttttgctt gcttcgtcaa gtatcctaat
    29161 ttttggatca tttgtccagt ttcatgaggc tgggtttcaa agaggtgagc gacatctttg
    29221 acggcttctc ttgtttgtcc tttgattcct gtatcagcga caatcaaaaa agcatcgatg
    29281 ttcaaagaaa agtagtcgaa aggatgccct tttgtaaaat aaatcggctg caagctgcta
    29341 gtagcggctg catcgattcc actaggatta ccgtgggcga ttttttccga aagctggaca
    29401 ttttctaata gtatttcacg agacaaagga aatgctaagt aatcataaaa agcacgagtg
    29461 actgctgtgg cgactgcagc gcttgatccc attccacgtt cagcaggaat cgtgctttca
    29521 atggtcagtt gcaagttttt ttggatgtca tgctgttttt ttaagtgaat gaataatttt
    29581 ttgatatttt ttaatgcatg aggagcttcg gctaaatttc ctgaatagta ggaagaaacc
    29641 agttgatcgt ccattgcatc cagctcttca aggaatgcgg tgacttttgt tgcatagaaa
    29701 ggaaaggcaa tcgctggttc tccataaaca accgcgtgct cgcccatcaa tatgatcttt
    29761 ccgcttgatt ctccttggcc atagtttgcc ataatctaac tccttctcac gtaaaagtga
    29821 tttttaagca aaaaataaag cgcccaaaac gagttgcgct gcttcacgaa tttttttgtc
    29881 cactaagggt ctcaaaaaac attcctcctt tattttacta aaaccatctc agaagtaaaa
    29941 ctaagaatac gttttctaaa gaaaaaacac ttttttctta agaatttttt gacttttttt
    30001 cttctttgac tagaaaaaaa tacaattgac actactagat attgggggta tatttaaaaa
    30061 ggttggagtt aaacacaata tttagtgatg aagtgagctg gaggtaaatg agcgtgatcg
    30121 ttttagcagg tacaattggt gccggaaaat caagtttaac agaaatgatg gctgaacact
    30181 ttgatagtca ggcattttat gaatcgattg atgataatga agtcttgccc ttattttatg
    30241 caaaccctga acagtatgct tttttgctgc aaatttattt tttgaataaa cgttttgcaa
    30301 gcatcaaaca agcaatgaaa gatgacaata atgtattgga ccgttcgatt tatgaagatt
    30361 cactgctttt ccatctaaat gcagatctag gaagagcaac agaaacagaa gttcgtgtgt
    30421 atgatgaact gctggaaaac atgatggaag aacttcccta tgctgcccat aaaaaacatc
    30481 cggatttatt agttcatatt cgtgtatctt ttgatacgat gttggagcgt atcgaaaaac
    30541 gtggtcgttc gtatgaacaa ttgtcctttg atccaagtct atacgattat tacaaagaat
    30601 tgaacagacg ttacgatcaa tggtatgaag aatacaaaga aagtccaaaa atccaaatcg
    30661 atggagaccg ctataatttt gtggaagatc ctcaagcaaa agaagaagtc ttgaaaatga
    30721 tcgaagaaaa attagcagag attcgccaaa ccaaagtagc catttgattt acagttgctc
    30781 aaataaaggg taaaccttta tttgagcgac ttttttcttt atactggaaa caaatgtcag
    30841 gaggatagag tatgcgggaa aaacactatt ttaatcaaga ccgtaatttt tggatcaatg
    30901 tacagcaaaa cgatgtgcta gctgttaaaa acttaaaaga agaatatggc attagtgacg
    30961 agatgctgac ttattctcta gataaaaatg aacgggcgcg cgtagagtac gattcttttg
    31021 atgaagcgtt actgcttgta tcaaatgttc cgcaccagca aaaagtcgat aatcattatg
    31081 aaactagtcc tatcgctttt attttaaaag aagacggttt gtttacattt accacgccga
    31141 ataccgagta cgtgattcga ctaattcgat cgcttttgga acgaatgcca gacatgagtg
    31201 tatacagttt attgtttcgt acattgtttt tgatttctga ttcctttttt cctttaatcg
    31261 aggaagtgaa tagtgaacgt cagcggctta atctgaaatt aagagaaaaa acaacgaaca
    31321 agaatctgct gcaactttca gatttagaga tcggtttggt ttacttagtt acaggaacaa
    31381 aacaaaatgt agtactttta gaacaaatca aggcattggc tatttatcgc aagttgtcag
    31441 aaaaggaaaa agaagagttg gacgatgcgc tgatcgaagc acgacaagca gttgaaatga
    31501 cgaacttagc ttcgcagatt ttagaccagc tctctggcac ttataataat ttgctgaata
    31561 acaacttgaa tgacacgatg aaatttttga cggtctggtc gctgatcttg accgttccaa
    31621 ctattgtgac aggattcttc ggaatgaatc tccagttacc ctttacccat tccgttttcg
    31681 gatggggaat cgccttgatc atcagtttgg tcttatctat ttggatgctt attgcactgt
    31741 ggcggcggat tcgttgatct agtctttgat ctgcaaacca agggcttggg cgatcacaag
    31801 tgcttgctct tggttgacga ttagtcccgc caaagaatct tgagataaag cgattgctgt
    31861 gaagaaatta gtcgtaaagt ctaatccctt cagagaagtt cgaaaccagt tcgaaccggt
    31921 caactgattg tcagacaaaa aaaggttttt ccaagtgacc tcataaaatt cgctgtcttc
    31981 taattgacaa tgatcgaagg agacagcttt caagtttgta ctactaaagg aagccatcga
    32041 agcaatacaa tcagtgaaag tacagtctcg aagataactt tcggcaaaat tcgtacctgt
    32101 taatttacat tgatgaaaca cgacttggtg gaaactgcca ccaatccact ccagattgga
    32161 aaaatcacat ttttcaaaaa tgacattact gcattcaaaa tgacgtaaaa ctgttttttg
    32221 catcgtaagt ttttggatat gactctctct taataccata tttttggcat cgagatagct
    32281 ttggtcaccc ccgttgatca gaagaccaga gaagatctcc tcatcttcta aataaaactc
    32341 tccctttgta agaagaggaa gagaaggtgg aataggttcg atttttttca tgtgggttca
    32401 cctcgttttt ctttagtata gcaaagaagc gggaatcact gctagaaagt ctgctaatct
    32461 aatcattttc agaaaaggaa gacaaactgt atgaaaaaca ttgacaaaaa gattagtttt
    32521 tgctatacta tgatggttga gaaataaaag cagaagcacc cgcttctcgc cttagttgat
    32581 aatgtcactg ggctagatag ttttcactgg ttctattagg tgaagtacgc gcgggttctg
    32641 taagagaact cgttttttta ttgccgttta ttcggtaagc ttttctttct ctcataatat
    32701 ttggaggtga atgaccatag caaaggatat gatggttaac gacggcattc gtgcacgaga
    32761 gttacgattg atcggttcag atggtgagca attaggagtt aagacaaaag cagaagcatt
    32821 gaatattgca gaacaagcaa acttggatct tgtgttagtt gcccctggtg cgaaaccacc
    32881 agttgcgcga atcatggact acggtaaata ccgtttcgaa caacaaaaga aagaccgcga
    32941 agcgcgtaaa aaacaaaaag tgatcaatgt aaaagaagtt cgcttaagtc ctacgatcga
    33001 cttgaatgac ttcaatacaa aacttcgtaa tgcacgtaag ttcttggaaa agggcgataa
    33061 agtgaaagct tctatccgtt tcaaaggccg tgccattacc cataaagaaa ttggtcaaaa
    33121 agtcttgaat cgcttagctg aagaaactgc ggatattgca acagtggaac aaaaagcgaa
    33181 aatggacgga cgcagcatgt tcttgacgct ggcaccgaaa aacgacagta agtaatttga
    33241 atgactaact ggctgttgga cagccgatag tcggataacg aaagattttg aggaggaaat
    33301 atagtcatgc caaaacaaaa aacacaccgc ggatcagcaa aacgtttcaa acgtactggt
    33361 aaaggcggat tgaaacgctt ccgcgcgttt acaagtcacc gtttccacgg caaaacaaaa
    33421 aaacaacgcc gtcaattgcg taaagcaagc atggtttcta gtggcgactt caaacgtatt
    33481 cgccaacaac tagcaaaaat gaaataagaa gtacaaataa cagaatctga agatttattt
    33541 ttattaggag gaattataca tggcacgtgt taaaggtgga acagtaactc gtaaacgtcg
    33601 taaaagagtg ctaaaattag caaaaggtta ctacggttca aaacacactt tatttaaaac
    33661 agcaaaagaa caagtaatga attcatacaa ctacgcatat cgcgatcgtc gtcaaaagaa
    33721 acgcgacttc cgtaaattgt ggattgctcg tatcaacgca gcagctcgta tgaatggctt
    33781 gagctactca aaattaatgc acggtttgaa agttgctgaa atcgacatca accgtaaaat
    33841 gttagctgac ttggctgtta acgatgcagc agcatttact gcattggctg accaagcaaa
    33901 agaagctttg gctaaataag ctaaacaatt ataaagagga aagaagataa cgaaaagtta
    33961 tgttctttcc tcttttttta tttacaatcc tccatcaaat gaaacaggac aataacgtat
    34021 aagtctaaaa tagcataatt aaggtttttt aattgaaaac tgaacattta tggtcaccct
    34081 ttaatgaaag cgctaactac ataagttaga atgagtttga ctgatatatt agtttgctta
    34141 tcagaaaaac aaaatggacg gaggaataac atgagtgata ttattattgg tattttgtta
    34201 gttatctcat tctttttcat ggtctggtac tgtgtaaaag gctacaactt gatggtcggc
    34261 tttgccatca tggctactgt atggatggga ttagcgctag tcggaaacac gttttcacca
    34321 aacccggcga tggaagggca aggagtaatt gatgtgttga cgcatatcta tacgacgggg
    34381 ccagctgagt acgccaaatc gatcttggta aatgtcttct ttggtgcctt tttcgggcgt
    34441 gttctagtag atagcggaat cgcagctacc ctgattcgaa aggtagttga acttggaggg
    34501 gacaagccaa gaatcacgat gagcttacta tgtattgtaa ccgctgttat attcatgtcg
    34561 atgacaggaa tcggaccagt gatttctatt gcagttattg tgttgccaat cttgatgtca
    34621 ttaggtattt cagtaccggt tgcactgttc tcatttatgg gctcgattat ggctggaatc
    34681 tttgctaata tcgtcaattt caaacaatat caaacgattt atgctggttt caatccagcg
    34741 gctgaaagct atacttataa tgactatttc caaattggta tgattgggat gattgtaagc
    34801 ttagttgtgg tactaacggt cgctaatata tcaatgaaca aaaagaaacg ctatgcaatg
    34861 gcagcaaacg taccagctga aggtggcgac gcaccaatga tctcatggtt agccgtatta
    34921 ttaccagttt taggggtcgt tcttttagat cttccaatca tcttaggttt tattctagca
    34981 ggtatctggg cattgctgtt tactggaaaa ttgcgcggag gttataaaga aatctgtcgt
    35041 cagtttgcga aattatttac agatggcgca gtagatgttg caccaatggt tggtttcttg
    35101 atgaccttag cgatgttcaa taattcagct gcgtatgctt ctccttattt ttcagctatt
    35161 tttggagatt ggataccgca atcaccatta gtcttggcaa tcgtatttgc tatattgaca
    35221 ccactaggat ttttccgcgg tccaatgaat ctagtcggtt caggctcagc tattttagct
    35281 gtcgtattag ctgttaatcc aacgatgtcg ccagcctttt tgttcccgtt atttgcaatc
    35341 acaacgattg ctcctcagca tttagatatt acacaatctt gggttgcttg gggattaggt
    35401 tatacaaaag taacttctcg agaatatatg aagaaatcca tcccaactgg ttggatcatc
    35461 ggagcgatct tatgcctgat cacgttctta ttgtacggga acgcctagta aacaaaacgt
    35521 cgataaaaac gattagatga atggaggaaa agaaaatgaa acgttttgtg cgaatgggaa
    35581 ttgatgttgg cggtacacat acgaaagcag tcgcaatcga taatgcgacg cacgaaatca
    35641 tcggaaaatc ttcagtgaaa acaacccacg atgatgtccg tggagtagcc gcaggtgtcg
    35701 ttcagtcttt tcaaaattgt ttgcgggaaa ataatatcag tccagaagat gttgtgtttg
    35761 ttgcacattc taccacacaa gcgactaatg cactgattga aggagacgta gcaaaagtcg
    35821 gcgtaatcgg gatggcaaaa ggtggattag aaggtttttt agcaaaacga caaactagat
    35881 tgaacgatat cgatttaggg aataagaaaa aaatagagat tgtcaatgca ttcttacctg
    35941 tcaaacactt aaatgtagac cgtgtttcag aaacgatttc ttctttagaa agagaaagag
    36001 cggaggtctt ggtttcttct atggcatttg gagtagataa tggggaacca gaacgagttg
    36061 tttatgaagc agcatcggta aaatcgatcc ctacaacgat ggcttctgac atcacaaaat
    36121 tatatggatt gacaagaaga actcggacag cagcaatcaa tgcatctatt ttaccaaaaa
    36181 tgctagatac ggcaacctct acagaagatt ccgtacgaga agcaggggtc aatgtttctt
    36241 tgatgattat gcgcggagac ggcggagtaa tggaaatcaa tgaaatgaaa aaacgacctg
    36301 ttttaaccat gctttccggt ccagcagcat cagtcatggg ctctttgatg tacttgagag
    36361 cgtctaatgg tgtttatttt gaagtaggcg gaacaacaac caatatcggg gtcattaaaa
    36421 atggacgtcc agcaatcgat tattcaattg taggtggcca cccaacatat atctcttcat
    36481 tagatgttcg ggttctaggt gtggcaggcg gttcgatggt acgggctaat cagtcaggaa
    36541 tcatcgatgt cggtccacgt tctgcacata ttgccggtct agattatgca gtatttacgg
    36601 agacagaaaa aatcaaaggt cctaaggttg aatttttctc tcctaaagaa ggagaccctg
    36661 ctgattacgt caaggtagtg atggaagacg gagaagaagt gactattaca aatacatgtg
    36721 cagccaatgt ccttggatta gtgcaagaag aacatttttc ttatggaaat gtcccatctg
    36781 cacgaaaagc catccaagca ttagctgatt attgtcatac gacggttgaa gacatcgcag
    36841 aacagatcat ggaaaaatcc tatgctaaga ttgaaccggt gattttagaa ttggcagaca
    36901 agtatcactt ggagaaagat cagatttctc ttgtaggtgt agggggcggc gctgcctcat
    36961 tgattactta ctttagtaat aaaatgggtg tgaaatattc gattcctgaa aacgccgaag
    37021 tgatttcttc tattggtgta gcacttgcaa tggtccgaga tgttgtagaa cgtatcatcc
    37081 cttcgccaag taaagaagat atacgatcgt tgaaaaatga agcgatgaat aaagcgattg
    37141 aatcaggcgc tacaccagaa tcgatcgaag tccacgtaga aatcgatcca cagacttcaa
    37201 aagtaacggc tatcgctact ggttctacgg aagtgaaagc aaccgatcta accaaggaga
    37261 tcacaacaga agaagcacta gagcttgctg cagaggatat gcgattaaat aaaaatgaag
    37321 tttgcttatt ggaaaataca cctttctttt atgtatgcgg cgaacagaat cgttcaaaaa
    37381 atgctggaag tcttcggatc atcgatcaaa aaggatttat caaggtccaa cgtggacatg
    37441 cttcatgtat gaaaacaact gcagccaatt atatgacagc tgtcgaacaa ctttgggaag
    37501 atatggcagt ttatcaaact gaattgattg cccgaccaga attttatctc tgcttaggag
    37561 caagagtctc tgattttaca gcgacggatc tggaacaact acagcttttg atggatctgg
    37621 aagtatctac tatggaaccg gaggaagaag tgatcgtcgt tgccggaaat atcaaacaaa
    37681 cataagttag aagagttact aaacgaatta caacagatcc ccgaagaaat ttggggattc
    37741 taccagtttc ggcgagattt attttggaaa aagattcctt tgtccaagca gaaaattctt
    37801 atacaacaat caatcgattg tggtatcgaa acggcatgta gcatcaaaaa aaagtaccct
    37861 tttgccgatg taggagaaat ttgtgaacaa atggctgttc caatcgtttc ctgtgaatca
    37921 gagcaaataa acgaacgaat cacttttgca acttatgcag aagatgaagg gattcgattg
    37981 atgacggagc cgttagaaaa attaaaatgt tcaggactag cttcgatctc taaagaaaca
    38041 gcgcaagctt tgattattgg acatgaacta tttcaccaca tcgaagcttc tgttaaggga
    38101 atttatacgc aaagcgaaaa aattgtgctg tggcggttgc ctttttatac acatcaatca
    38161 aacattcgtg cattgagcga gatagcagcg atgagttttt caaaagagat gaatcaaagc
    38221 gatttttcgc cttatgtatt agaggcagtc ttactttggc catataatga aattcgtagc
    38281 caagggatct tagaagaaat aaaaaaaata gaaaaaagat gtacggagta tgatttagat
    38341 tacaaataaa gagactgtga caaaagtcgt gtcacagtcc tttttttccg aataaacgat
    38401 gttctcctgt caactcctcg gtcacaagtc aaaatattca acaaacatga gaagctgttt
    38461 tttgaaattg ttccttgtga ctcggagatg aacggcaggc tcacgacctc ttggaaaacg
    38521 gtgttcaaaa gcttgcatct gcggtaataa gtccagccaa gttaaaaaca taagaagcta
    38581 tttttacttg gctgttctta ttacttgatg cagggcagct ttttcacaac ctctcaataa
    38641 acggtgtgca atcagctgac cctcggtatt agctcaaaaa aaacggcaaa atatgaggaa
    38701 ctattttgcc gtttctttct ctaatactca ggtcaaaacg ctgattccaa aacctcttat
    38761 ttgatgggtc tgtcctgaat atcttcaaaa taatcggggt aattatgaat cacgtattct
    38821 tgctcctcga taatcatatg taaatgcatc gtgcaaagaa atccgacttc atcaaagtta
    38881 tgatcaatca ttgattgaag cattgtctga tgttcatcta atactcgacc ccagtctaat
    38941 tctgaaatcg tcaaacgtaa ccatctgaaa cggttcaagt gcgtactata actttctagc
    39001 caatcccaaa tttctcgttt tccagcaatt tcataacaag ttcggtgaaa atcagtatcc
    39061 aaatcaaaaa aagctttttt attttgagcg attactgcct gatcggtttt tccaactttt
    39121 cccgcgtata acgggctaat gaagcagatc ggatatcgat ttttgaaaca taagtgccgg
    39181 actgtggaat ggtttttaca agctcttgat tgcgcagttg gatcagtgct tctcgaatcg
    39241 gtgtacgccc gatagctagt tgttcttcta acactttatc ggagatttta cttccaggtg
    39301 ctaactcgga ataaatgatt tgtttacgta tagattcata agcttgctgt tgcaaattat
    39361 tgataaccat ttaaccttcc tttctatgca gatataatct attataacat aaatcgctta
    39421 caaatcgtgt gggcataaaa acacagtctg caaaaaaagc cctgataggc atgcctatta
    39481 gagcctcgaa aagaaaaata ttgaatcaat ctggtcgtac ctcttgtatc ggtttgacac
    39541 gaccgccgat tcttttagca aaagcttcgg attctttttt gtctttgaaa atgagcagat
    39601 tgtctaagtt tttttcccga gtgcgacagc cagttttatc gatgtaaccg tgcattactt
    39661 taacgacata catggggatc acctgctttt ttcttttcat tatacgaact actcgacaca
    39721 atacaagaaa aatgcttaga cggtctttat taagaattta catcatccaa agaagcgtac
    39781 gcttggaata actgatctaa ctccggattg actttgctca gcttcactaa tcgttgcgaa
    39841 tcagaaagta aaaaacagtg tttactactg ccagtagttt ttaatttttt gtcttcagtt
    39901 cccacaattt cgtagctaaa atccaaccgt gtccccgtat acttttggat agttggatgg
    39961 atgctcactt tttctccgta atggatcatt tctttatagc tgcaatttac ttccagaacg
    40021 gggatgatga tcccagattc ttcgattttt ttatagggaa accctagatg taccaataag
    40081 gctacccgag cctcttcaaa ccagcggata taattgctgt gatgaataat ccccatttga
    40141 tctgtttcat aataaaaagg ttctcgcaca taacctgtaa atttctccat gactcatgcc
    40201 tcgttttcca ttgatttttt acaaaaataa ttcatccatt tcggaagtgc ttcgctgatt
    40261 tgtgtcggca aaacaatata ttgttctttt gccagctggt ctccaatgaa actatgaaga
    40321 taaatagctg ctgcaatcgt ttggtcattt tgaggaaact gggctaaaaa tcctgtgatc
    40381 atcccagcta aagtgtcacc catgccgccc gttgccatag cagcagaacc taaaggattg
    40441 gtgtagaagt gctggtgacc ataaattttt gtctcatgac ttttcaaaac gagcacagca
    40501 ccgatttcct gttgcttctt tttgttttct ttatcccgtt gttcttgtat cggtagagaa
    40561 ctcaaccgtt gccactccat ttgatgaggt gtaagtacag tttgttcggg atagggtagc
    40621 aaaagatgat tagcagcaag taaacttaaa gcagagccat caatcaccag ccattgttct
    40681 tttgattggt tttctagtac ttgtttgaaa cgttccaaac tcttagaaga agtacccaat
    40741 ccgggaccaa tcaagagtac atctgcttgc tttattacgg aaagaaactg gtcagtatcc
    40801 gtccaaacta caatcattgc ttctggcaga tgactgtgaa gagcactccg atttttttca
    40861 tcagttacta cagtcgtgag acccgctccg ctgtgtacgg cagctaaagc actcataatg
    40921 attgctccgc catattgttc attgccgcca atcaaaacga tacgtccaaa tgttccttta
    40981 tgtgaaattt ttggacgagg tgtgatgact cttttcacta gttgttcgtt tatcagcatc
    41041 taaaaacctc cttttactca ttatagcgta tatttttttt agagaaaaac agataagaaa
    41101 aggaattgtc agattttttg aactattttt ttctgtaatt tgtggtatca tgaacacgaa
    41161 gacttaaata agtggaggat taactttatg acaattgatt ggcaaaaaga agtagaagca
    41221 cgtaaagaag acttgcttga agacttgaaa aatcttttac gtgtcaacag cgagcgcgat
    41281 gactcaaaag taacaccaga tgcaccattt ggacctggac ctcgcgacgc attgaaacat
    41341 atgttagctt atggcgaacg tgatggattt aaagtaaaaa atgtcgataa ctatgcaggg
    41401 catattgatc ttggcgaagg agacgaaacg ctagggatat ttggacacat ggatgtcgtt
    41461 cctgcaggag atggctggga cacagatcct tatgaaccag taatcaagga tggaaagatc
    41521 tttgcacgcg gatcaagcga tgacaaaggt ccaagtatgg cagcttacta tgcgatgaag
    41581 atcattaaag aacttgactt gaaactatca aaaaaagttc gcttcgtagt cggcagcgat
    41641 gaagaaagcg gctggggcga tatggcttat tatttcgaac atgaagaaga accagatttt
    41701 ggtttctcac cagatgctga attcccaatc atcaatggtg aaaaaggaaa tgtttcttta
    41761 gctttacgct tcaaaggcga caatgcagga gattatgtct tgaaatcttt tgtttccgga
    41821 cttcgcgaaa atatggtgcc aggaacagca actgcagcac ttcaagtacc aagtgcagat
    41881 gcagctatcg cgatggaaga agcattttac caattcatcg aagcaaatcc agtaagcgga
    41941 acgattgaag cggacaatac gtatgtaaaa atcgaattag ttggtaaagg cgcacatggt
    42001 gcaagcccac aatctggtat caatgcaggt tctttcttgg cattgttctt agataactat
    42061 gaattcctag gatctgctaa acaatttatc catgtagcag ctgcttatgt ccatgaagat
    42121 ttttatggag aaaaactagg agtcgcttat gaagatgaaa aaatgggcaa attgacaatg
    42181 aatgctggac tatttgcttt tgaagaaaat ggtacagagg aagcgaactt catcaatatg
    42241 aatttccgtt ttccaaaagg tgtaacagta gacggattgc aaagtgacat cgaacaaaca
    42301 gtggggcaag aaggcgcaac agttactcga ggtgctcgcg taatggaacc acattacgta
    42361 ccaatggatg atccattggt ggctacatta ttgcaagtct atgaagacca cactggagaa
    42421 aaaggctacg aacaaatcat cggtggcgga acttacggac gtttgttgaa acgtggcgtt
    42481 gcttatggag cgatgttccc aggatatact gatacaatgc atcaagcaaa cgaatttatg
    42541 agtcttgatg acttgttcag agcaacagca atctatgcag atgccatcta tcgtttggcg
    42601 aaataattaa ttaaaaagag gatcaagaat tgcaaattat ttttgcagtc ttgatccttt
    42661 ttttactttc tactgtggta ttcatgataa acatgatata gattcaattc atattctttc
    42721 ttagcgttcg tgacgactgt atccaaaatc aaccctgtta ctaatgaaag aagtgctaaa
    42781 gtcatcaatc cagtacttaa aatcgcagaa gggatgcgtg taataaagct tgtcagcata
    42841 tattcgcgaa tcacaggaat ccccgtgacc aatccaaata aaaagaagaa gatggtccaa
    42901 atcccaaaga aaagcaaagg cttataatct ttaaacattt taataatcat catgatcact
    42961 ttgaatccgt cagagaatgt attcaatttt gattcgctgc cttcaggacg atcacgataa
    43021 tcgattggga tttcaacgaa cttgaatttt ttatctaaag catggatcgt caattccgtt
    43081 tcgatttgaa aaccagaact cataatagga aaacttttga caaagatacg attgaatcct
    43141 cgatagccgg tcatgacatc aagaattttt gttttataca ttctagtaat tgtatttcta
    43201 acaaggttat ttccaaaatc gtggaaaggt ctcttattct catcaaagta ggttccattt
    43261 gataggcgat caccaatgac catatctgct tcaccagaac gtaatttctc gagcaaacca
    43321 tgtacagctt ctgcaggata agtatcatcg ccatctacca ttaaataata gtcggcatcg
    43381 atatcaaaga acatttggcg gatcacattt ccttttcctt gacgaggttc tttttttacg
    43441 attgctccac cttgaacggc caattcgtat gttcgatcgg tcgaattatt atcatagaca
    43501 taaatatctg cttctggtaa ttctcgttta aagtctgcaa tgactgttga aattgttgct
    43561 tcctcattgt aacaaggaat cagaacagca attttttctt gttgttccat ttttcactct
    43621 ccttaactat agaaaacaaa agctaaatta aaaatacctc ataatcaaag gaaatgctag
    43681 tttttcccgc taaatatcat ttatttaaaa agaaaatact ggaatatatg tttggaaagc
    43741 tctatctaaa aaaccaccca ctacaaaaga aggacatgat acctctcttt tgaatagtgg
    43801 gtgcgtattc gttctctcac ttttttgacg tattaatctg ttgcaccttt ttttcttgaa
    43861 atttctaata cggttcctgt atgagcatct gctaaaaatt cataataaac agtttcgcca
    43921 tcttctattc gagaaagacc tccccgataa gcactcgacc gaacggcgaa tttcctaata
    43981 ggttcctttt caaaagagat ccaagaacct tcgattgcac cttcttttag aaaagatgac
    44041 ttgatatttt caagtacttg gtctgctgac aatacttttt tgcgatgata ccaaatcgtt
    44101 gaagctaccc cgctcaataa tcctagaccg attccaactg ctaacccgcc tttaaaatag
    44161 cttagttcgc tttcttcata catgtggaca tacctccttc ttctcacttg ttactccttg
    44221 tgcttatttt accacactct catattttct ttgaaataaa taaccgctac cagaaaaaat
    44281 aagctataat aaatacgatc ggtctgcaga aaaaatcata ttttatccgc agatcaatat
    44341 aagtctgaga ggagtttagt ctgaaattta gacgaatagc atatggaaga aaaaacattt
    44401 caacgaatca aagagttaac agaattacaa ggaacaagcg gttttgaaca agatgttcgc
    44461 gcttatatgg aaagtcatat ggaaccgctg gtagatgagt tacagttaga tggtttgggc
    44521 ggcatttttg gtctgcgcca tcatgaagaa gcggatgcac cccgtgtaat ggtcgcagca
    44581 catatggatg aagtcggatt catgctgaca caaatccaag aaaacgggct ttttaaagtc
    44641 gtacctctag gcggctggaa tccttacgtt gtttctgctc agcgttttac acttaaaacc
    44701 tctactggta agaattatcc atgtatttct tcttccgttc ccccacattt attgcgagga
    44761 acaagcggac aaaaatcagt agaagtaacc gatattttgt tcgatgctgg gtttgaatca
    44821 agagaagagg caatgagtta cggtgtcctt ccaggagaca caatcgttcc ttacgctgaa
    44881 acgatcaaaa cagccaacgg aaagaatatt atcagtaaat catgggacaa ccgctatggc
    44941 tgtacaatgg tattagaagc tttagaagcg ttgcaaaatg aaacattagg tcatacattg
    45001 attgcaggcg cgaatgtcca ggaagaagta ggcttgcgtg gttctaaagc ttctgtcaat
    45061 aaattcaagc cagatctgtt ctttgcagta gactgctctg cagcagatga tacagtgacg
    45121 aaaaatggca cattcggaca tttaggagaa ggtacattga tgcgtatcca agatccaggt
    45181 ttgatcatgc ttcctcgttt gcgcgagtac ttgctggata tcgctgaaac aaacaatatc
    45241 ccttatcaat actttgtttc aaaaggcggt acagatgcag gtgctgctca tacacaaaac
    45301 gaaggaatcc caagtacagt gattggcgta gtgggacgtt atatccatac gcatcaaacg
    45361 atgttcagta ttcgcgattt tgaagctgca cgagaaatgt tgattcaaac actgaaaggt
    45421 ttggataaat caacagtgaa tacgatcgta tacggaaaat aatgcgatag tgaaactata
    45481 aaatctggca aaagattgct ttttgccaga ttttttttat aaaaagagga tcaatgtttg
    45541 ttagttcgaa agaaaggtgt ataatttaat tgaaaaatac ataaacagaa agtagaggac
    45601 aaagaatgat tatcccaaat agtttagaag aattagcagg ctacgtagaa actggaaaga
    45661 gtgtattttt ctttactgcc ggctggtgcg gagactgccg ttttatcaaa ccgcaaatgc
    45721 ctgaaattga aaatgacttt tctgattggc aatttattga agtagaccgt gacaagtaca
    45781 tagatgtagc cgctgaatgg aacatttttg gtatcccaag ttttgtcgtg atccaagacg
    45841 gaaaagaatt aggtcgtcta gtgaataaag atcgtaaaac aaaacaggaa atcgaatcgt
    45901 tcctagaaag tgtaacaaaa ggctgacatc tgttaggagg ggtcaagatg aatcaagaat
    45961 ataagaatat tttagtaggt atcgacggta gtgaacaagc acttgctgct ttcaaaaaag
    46021 cggtagaagt ggctcgccgt aataatggga aagtatatgt agcaaacgta atcgatcagc
    46081 aattttataa ctttatgggc tatgcaccta ttgatcaaaa tctagtcgat cagcaaactg
    46141 aaacagccaa ggaaatgatc gaagaatgta aagaatatgg gaaatctgtt gattacacaa
    46201 atatagaagg aattattgca tatggttctg ttcgtgaatc catggcagtc aaattgccaa
    46261 aaaaatatga gatcgatcta atcatggttg ggcagtcagg tctaaatgca gtcgaacgct
    46321 ttatgacagg aagtgtagcc agctacgtga tacgtcattc accttgtgat gtcttgatcg
    46381 tttctgacga agaagaacag ccaagtaatt aagcaagtgg aacttgtacg acctttttaa
    46441 tcaattaact aaaacagtaa agggactgtg acaaaagtct tgtcacagtc ccttgttacg
    46501 aataaatggt gttccagaag aggcttcttc ggaaataaag catgaaaaaa atttcatgca
    46561 gtgaatgcaa ttttttgtta agataaatct cagcaaagga taatggagga aagaacatga
    46621 tttttgctta taacaaagca cacgtcggag acaccttgat ggttattata gccgacgata
    46681 aaggaacaga aaacactgtt gaacgcaaat ggaatgttgc tcggatcaaa gatgaacaag
    46741 gtcaagttgt tgcttggaac tttttccata tctccgatca tctaacaatc gaagggaacg
    46801 gccaagtaag cttaacagat gaggaattag cgaaattgaa tcgattgatc aaagaagcag
    46861 gattcgaaga acagcttgaa gctgatcatg aaccgaagat cgttgtcggg tacgtaaaaa
    46921 catgcgtccc acatcctgat tctgaccatt tatcgattac tgagacagaa gtagacaatg
    46981 gtacagtatt gcaaatcgtt tgcggtgcac ccaatatcga agctggacaa aaagttgtcg
    47041 ttgcaaaacc aggagctatg atgccagatg gaatgatgat ctggccagga actttgcgag
    47101 gggtagatag ctatggaatg atctgttccg ctcgtgaatt gcatttgcca aatgctccag
    47161 caaaaaaagg aatcttagta ttgcctgagg atgccgtagt cggagaagca tttccaaaat
    47221 aaagaggttg tgacaagtct ttgtcacaac ctctttttta ttaattttca ctattttgat
    47281 tttgttttaa tgccgattga tcgatcgtca attcaacagt agttgttttt tctttcgagc
    47341 cttcatagta agtgattttg acagaatctc ccactttttt cttatacaaa gcagattgaa
    47401 gttctacacc agaagaaact tctttgtcat cgatcttagt aatgacgtcg tattgtttca
    47461 atccagcttt ttcagccggt gtagctgttt ggacatttgt cacgatgaca ccgttagtta
    47521 cagatgaagg aatcttcaag atttgttctt gttgctgagt agaaacggca gataagtcga
    47581 ccattgtgat acctagagct ggacgtgtca cttttccgtc tttttccagt tgattgatga
    47641 tattcactac atcgttactt ggaatagcaa atcccattcc ttctacgctt acattagaag
    47701 tagattcaga agtacttgcg atcttacttg agttgatacc gataacttgt ccttcgatat
    47761 taactaaagg accaccagaa tttccagggt tgattgctgc atctgtttgg atcgcattga
    47821 tattgactgt ttcgttcgat tcattcgtac ttgtcacttg tcggttcaag gaagaaatga
    47881 ttcctgaagt gacagaattt gcatattcag atcctagtgg ggaaccaatc gcaatcgcag
    47941 gctcaccaac cttcagagca cttgagtcac caaaagaggc aactgtttcg actttgtctg
    48001 aattgatctt caacaccgct aaatctgaat aagcatctgt tccaactaat tcagctttta
    48061 ccttcgtacc gtctttcatc aagacttcaa gaccttgctg gccatctact acgtgattat
    48121 tcgtgactac ataagcagta ttcccgtctt ttttgtagat cacgccgctt ccttcactat
    48181 aagcttccaa attactatca tctgagctgc tactttcttc ttgctgcccg aatagtccgc
    48241 caaaaccgct tgattggttt tgactttgta agttgataac agaaacgaca gcgtcttgaa
    48301 ctttatctac cgctttggtg atatcagaat ctacattgac tttgacattt tccacaactg
    48361 tttcaccggc agaattctga ttgccgcttg tagcagtaga actattgttg ccagtgccca
    48421 tcgctgcata aaaaatgcca gctgtcagta gtcctccaac gatccctcca acaagcccca
    48481 gacctaactt acgccagagg ctattatttt tacttttttt catctttggt gtcacatttt
    48541 ttctatccat gtgttcctcc tccaattaca ttcatttatc tactgttagt atagtcttat
    48601 ttgttgactt tagtctactt tgagactgtg aactttttat gaaaaacttt aggaaaaatc
    48661 attgttttca gatgaaaata tttgattttc tttttccaca gatactgtgt aaaactacgc
    48721 ggataggatt ggaaaaataa gggataaaac atatccacag cctgtgtata aagtggataa
    48781 attcttataa aacgtatgtt tgcctaatga atgtgatgaa ataaggtaaa ataacactgt
    48841 tttctgtgga taaacctgtg gatgttgtgc ataactgttg gggaaatctt tttaacaaaa
    48901 atagccaaaa taaacatata gacgaaaaaa ttgattataa taaacaaagt gagcatgaag
    48961 accaaaggag agaaaacatg aatatcaaaa ttatctcagt aggaaaatta aaagaaaaat
    49021 acctgatcca aggtatcaat gagtatgtca aacggctgaa tgcctatgca aaaatcgaat
    49081 tgatcgaagt tcctgacgaa aaagccccgg agaatttaag cgaagcgcaa atgagacaag
    49141 taaaagaaaa agaaggggaa cggatcttag cgaaaatcaa agaacaagaa tacgtctatg
    49201 ccttagcaat tgaagggaaa aatcctacaa gtgaatcttt tgctaaacaa atcgaccaat
    49261 taggtatcca aggaaaaagc caccttgttt ttgttatcgg cggctcttta ggactcagcg
    49321 aagccgtcat gaaaagaagc aatgctcaga tctcttttgg aaaaatgacg tatccacatc
    49381 aattgatgcg tctgatcctt gtcgagcaaa tctaccgtgc cttccggatc aatgcggggg
    49441 ctccgtatca taaataatga tatttaagat tgaatgctcc tgaacactaa gttagctttt
    49501 cattgaaatt tatatataaa aaagttaact tgaaaatcgt tgagaatttc aaaaaaataa
    49561 taataacttt attatgtatt caaatttgtt acaaaaaatt gaagatgaag agcgctctct
    49621 tgtataaaga gacgctcttc atctttttaa tttctacttt gttgattaaa taatgaaatt
    49681 ctttcttcaa tacttgtttg aatttttact gaaagctctt tttcatctga tgaaggattt
    49741 aataagtgaa aaaaaatacc ttctttttca taatatttag gtgcagtttt ttttcttcct
    49801 tcattggaag gatataaagc aaagacagca gagacagctt gcaaagaacg tgtaagaatt
    49861 tcaggaaatg ctagaatact tgacatagta ttttgtttat aagccattaa ttgttgacgt
    49921 tgcctacctt tatcattatc aagtatattg tctagttttt tatattttac ttcaaatatt
    49981 aagcttccga tatagtattt atcttgaagg ataatgtcta atctaatatc aggtttattt
    50041 cgttttgaag aggtttttac tgggatatct agtgtattgg agaaatattc tttttccatg
    50101 gaattattat atacaagatt aatacgtata tcatttttac tcaatactac ggtagtgtct
    50161 tcatgtaaaa acggcaattc ttgtgaaaga atatcattct caaaaatcca tccagaaatt
    50221 ggagtgtagc cttgcaggga tagagatcta ataattttta taaagcacca aatttcatag
    50281 agtacatctg tacttttcca ataatactga tatctatttg aaaaatttaa agtattacga
    50341 ttgtttctac tttttaaata cattttatat atagtgttat atttagggtt cataacaagt
    50401 gattttggaa catttatagg tcttcttgat gaaatgtttt tcattactgg tgtgtctaaa
    50461 aattcaagga tataagcata aaaatgtttt atcttttgct gattgttttt caaattttca
    50521 atctttctat tatagctatt tgtattgtag ttttgtacac tttgagaata cgcgctagta
    50581 aacttatctt ctcttttttt ctcttcaata ataccttgta ggattttctc taaatatcta
    50641 tcagctagaa gtgaaaaatt tttaaaataa gataagataa atttgatcca ttgattttca
    50701 ataatatcat attttattat gcggctaggt gtatatagta gcccacgttt ttctggatgg
    50761 atttgcaact gtgaaatagt tttttgatcc actaaatttt tgcttccaat tggtttccag
    50821 ttatatcgtt tgtcaattct atattttgct tcttttttta aactttcaag agaaactatt
    50881 gcttgaggta tattgttctc aaactctaat attcgttgaa aaagttgatc gttcattaga
    50941 taatttgaag tagtaatttc acgacgagaa gtttttttag gaataaaagt tctagcaaga
    51001 ccgccaacca ttttttcaat ttcgattttc attttttccc attctggtgt acctaaatct
    51061 ttaagtatta tttcaaatcg agaataaaag atagtttcac ctattttaac gtaaagagtg
    51121 taataacctg gaataagagg tactgtttta ccttgatccc tattataaat gattatatta
    51181 tcatcacttg gaatatagca aatatctcca ttttcctctt ttacttgatt ttcaatcaaa
    51241 taatcatcta attctggtat atatagtttt gcgtgtttgt ctatactgtt aaatgtaaag
    51301 cttagattag aaaattcttt taccttaacc ggtgtatact ctaataacga tgcctcatct
    51361 tgaaaaaata aaagttcata ttcttgttct tcacttttat aaccaaagtt taatttcaga
    51421 ctaaagggta aatccatgta aattcaactc cctagctttt tgcaaaagaa tttttttagt
    51481 atatttaaaa tctgaagact caggatattc attaattatt tgttcaaatt cacccacttg
    51541 ttttaaatca ttctcattcc atttaccaac taattctgat aattgttcat cagaacctct
    51601 gattttactt aatactctct gtacaagctg aatatcaata gcttcttttc ttgataagtc
    51661 attttgcact ggaagatttt ttaaatattc atcaatttgt tttaatattc tccaaccgat
    51721 accgatattt ttgtctttag aattaattgc taaatggagt ttccaaaaca tttctttttc
    51781 tttctgggtc aaaccattag tagggttaga gtttttaaaa tttttgaaat catcatattt
    51841 aagttgatta cgtttctttt gatctgattg aatatagtca tttacttcac taatttcatg
    51901 gaatggtact aactcaagtg aaataatgtt tgatctatcc aaaactttat ctgagaattg
    51961 atgagtagat tcatctgtat ttattgttcc tacaaataat atgttttgtc ctacttcaat
    52021 tgtagaagga taggttgaag agttatataa tttattttct agatcttcgt tatacagttt
    52081 gattttccta gtatttggct ccatttctaa aactgaaaga aattgggaga aataatgttc
    52141 aacccgagct aaattcatct catcaaaaca aaccatataa atattttctt tatgtcttga
    52201 tgcttctaat agtgcatcaa ttagaccgct atctcctgga cgatagacag aatttacagt
    52261 atcagcatag cccaataaat cagaatcatc ctcccaaaag ggtctcacag aaataaactt
    52321 tatttgtgta tctgataatt gaagtgcttt tgcataggat gttactaatt gtgatttacc
    52381 ggtaccactt agtccagcta ataccaccaa actatcaccc aacatagcag tatgaaaatt
    52441 ccataagtct cgttttgagt aatgtaattt actacgaatt gtgagctgat taaatctttc
    52501 tataaattca ttatgttcag agaagtgatc attttgttga atagcgtgtt tatcttctaa
    52561 ctcagatata tctatttgcg tttgttcagt aataattgaa cttactggag atattttgga
    52621 atcagagata ttttctatgc cttcgttaat atctttttta gtttctataa ttttttgaag
    52681 taatagatag ggcacaaaaa ttatatcttt tgtttgattt ataaaatcat cgtaacctac
    52741 atagttttta ctaccttcat caataaactt tttgtaaaaa ttatcttttt ctatcctata
    52801 tgctacaccg tacattgaat tgttttgtcc gattatttca ccaaataaaa ctcttgatcc
    52861 atcagtgttc tcccaaaaaa catttaaagg gtaatcttca ttgtcttttg agaaatttat
    52921 aatttttccg agtagtttgc cgtttagtaa ttggttttca aaacttgtct cgtctttgat
    52981 tacagaatcg ctgttattta tagaaaagac cggtataggt actaatgatt cattctcttt
    53041 tattaaattt ttaaaaactt cagactttgg tttggggatt aattctaaat catcaccttg
    53101 atagtaattt cttgcttgtt catgatttct tttaattttt ggtgtacaaa cgataatata
    53161 aggatctaaa aattctttaa gtgattgggc acgagtacta tgagattcgt ttatatcatc
    53221 aataaaccca aatttagtaa gcgtattact atatatttgt ataccctcta cattatcaat
    53281 cacactactg gggaaatctg aaagaggagt cataaaaaag tacattacat catccgagtt
    53341 tattttaatt ttatttaaat catcctccaa ataaccaata atttggtaat cttgtttacc
    53401 ttgttttaaa accatttata ttttcctcct tcataagcat agtaaaatca tttaattctt
    53461 gaatttttat tttatttttt aaactttgta taatcttttt tttcattctg ggaattaatt
    53521 gaaaggttgt aatccataat tcattaatat cattttcttc aattatttta atgatatctt
    53581 cgagaggtgt atcaggatta gtgattataa aattatagtc ttctctaata acaatttttc
    53641 ctggaacacc aattaataaa atctttttta tactttcttt tgtttggtgt gaaatagttt
    53701 ttactgtttt gcttgtattt ataagactat tacatctttt tttcagttca acgatttcat
    53761 tttctttatt tttaagcgtg ctatttaaaa tagagaattt tttttctaaa ttaagatact
    53821 tactttctga attttttaat tttaataaac tattagttat ttcttcttta tatcgattta
    53881 tttcacattc cttttcagcg aggaattttt tttctagttt gctgagttct cttattttat
    53941 cgttattatt tttttctatt tttttcttga gtctttcatt ttcttttagc aatacttttt
    54001 ccctattttc agcatcaatt ttgtcttttt tataaagggt taataaatct tccatctttt
    54061 tatattcaag tgagatatca gtgcaaccct tattcttttt tttattttgt atatatatca
    54121 aagaattatt cttaaatgtt cttaacccat caatattttg aaaaaaatct acaatgttgt
    54181 cttcatctgt ttgttcaatc aaatagatat aaaatgaaaa gggggattcc aactctttat
    54241 ttttaatttc ctcaaaaaat ccttctatgc tctgaataga agtactttta taaatatttt
    54301 catcgtttgc gacgatatcg tggaagtacc cactactaat atatttaaat atatatctta
    54361 aatttttttc tttaagaaat tggttaaata acctgttttt aaaagaatca gatgggtttt
    54421 taggaataat agatgagcca cttaacttct gtggaagtac tttcgctaat ttattaagat
    54481 gttccaaatc aagagaatga aaaacatctt ccataaaact tatagttaaa gctttcaatt
    54541 ttgacttcct ttcttgtatt atttataata acaatagtag tataacatta ataggatagt
    54601 tcattaagca aaattaagta tcttagttac taataactat ataaatttta aacttgtagt
    54661 cgcaatttag tatagaggta ctaaatatga aaactccata cttttagaaa agcatttctt
    54721 atatttagtt gtgatgtcta ttcagttaat tgaaataaat aatatagcaa tgaaatagag
    54781 ataaattcaa atatatatta tatccatgaa gtccaatctt ctttatagaa gattgggcta
    54841 ttttttacga caaaggaggg aaaagaaatg tttcaaaata aaggacaacg ttatgtcaca
    54901 aagggagtaa tggacagttt actggtggaa ttacaaactt tatgttggaa tttaatcgat
    54961 caaaacgttc aaaagaagct tcctttagac tatcttcaaa tctttgaatt ttcgatagaa
    55021 aaaggaaatc aaaagttggt tcatcgtcaa gaagaaccgg aagcaagaaa agagtatctg
    55081 atttcaccta agcttcgttt ggaatcagtg tctcaaaaaa tatgggtcat tgattcgggt
    55141 gagtatcaaa cgatgttatt accagaagaa tactgatatc taaaagaaag gagcgaaatg
    55201 acttgttaga aacggctatc gaagtactgg aaaagtgtgc acagctagtc actactcctg
    55261 aagagtgggg ctatgaatcc gttacgatgg aaaaagagga aattgaaatg ggtacgcttc
    55321 ctaaaaatgt tcatctacca cgtttagtga tgacacatct ttatatttat tgcgcaccag
    55381 aagatggaaa agactatgta gtttatttca ttacagatat taccagccag cgagaatttg
    55441 tttgtgggtt actggtagaa ggacgattgg tttggagtca gattggagga acgaatgaat
    55501 aagatcgatt atttgagaat gattgcgaaa tgtttagaag atatccttac cgcgatttat
    55561 cgaattctga agaaaaaagg agaaagaata tgaaatattt tcaactagta ttgacactta
    55621 taacggcaat ggtaattgaa ttgcttgaac aaaaattagc ataggagaaa aagagatgat
    55681 tgaaaaagaa ttagtgacca cacaaacaga agtttggcga gatcctcatc atacccatcg
    55741 ctatgttttc aaacgacaat gggcaatcaa aggaaaagaa gagaaagaaa aattagcagt
    55801 agtcattacc attcgtccaa cagatacaga accatttacg aatgatttga gtatgttatt
    55861 aatcgaaaag aatatccgac aattgggatt tactggtttt attgccgtga atcttttttc
    55921 gtatacaaaa gcgaaaagtc ctcgggtatt ttctcgtggc aatgatgaac aatctttgga
    55981 aatattaacg accattttta cagaaaagaa aatcaacact attatttttg cttgtggttc
    56041 gattacggca acgagtcaag tggcttatga acaagcaaag accatttacg atcaattgag
    56101 tgcgaaacaa aagaagatga ccaaagtatt gataaatgca gaaggcaagt tatctcaccc
    56161 attaagtatt catgttcgta atgaatggca attgtcggat cattctttgt tatttcaata
    56221 aacgaaaata agtattcaat gtatatgttt ctttttctgt tattttactt gttcttttgc
    56281 agactaaaca acttgtaaaa cctcttgtta tatgcattat caatgaagga atcaatatga
    56341 tatttttaaa atgtcagggg aaatggaggt gagcaagtga aagtagatgg ggaatgtttg
    56401 acgagttcgt ataaaagtat ctatgaattt tttgaggaaa aaggactaga cacggattta
    56461 ctttatcagt tttatatcgc ttttcgtggg caacagttgt cgtttccaat gaaaatgtat
    56521 gaccgagaat tagtcgctca aaaaattgaa acaatgatac aagaaaacca ttccattgat
    56581 tctaggaaat taacggatcg gtatggtttt tcaacgagat ggattcaaag tattatcaga
    56641 caacaacaaa aggagcaaca tgtacatggc taatgaagaa acagtaggtt tgagaatcat
    56701 agaagaagca ttcaaattac caatggtcaa agttgatcgt cgagcatttt tgattcaaac
    56761 atttcaaggg aatgtttctg atattgaagg actcatagaa aagggtccac aagcattttt
    56821 atccaaagaa atgctagatc gtgaagcaca aaaatgtatt caatcgatta ccttgaaatc
    56881 aagtgcggta tcgttagcaa ctggactgcc aggaggtatc gctatggcag caactattcc
    56941 agcggatctc cttcagttct ttggttattc attacgatta gcacaggaaa tttcgtatat
    57001 ttatggattt aaggatttaa tgggagagac tggagagttc agtgaagaag caaagaatac
    57061 gctgatattg tatttgggaa ttatgcttgg agtaacttct gcaggttctg ccgtacgagc
    57121 gatgtctgga aagctgtcta cacaagcatt gaaaaagatt cctcaaaaag cattgacaca
    57181 aacgctgtat tatccagtaa tcaaacgagt actaggtatt tttggtacaa agttaactaa
    57241 aaataccttt gcgaaaggta tttctaaagc agtaccagtt gtgggaggcg ttgtttcagg
    57301 aggcatcaat tacttgtcta tgaaaccaat ggcaacgaag cttcaaacag agttagggaa
    57361 aaatgtagcg tatacagaaa aaaatctcca acaagattta gatattttag aaggtgaatt
    57421 tgaagaagta tcttctgata tcgtgtcttc tgatacagtt ctttctcaat tagaaagact
    57481 ttctcacttg ttggaaacga atatgattac agaagaagag tttcaacaat tgaagcaaga
    57541 gctgttaaag aaataattat ttagaaaaag caaccactta tacgggtggt tctttttctt
    57601 gaatgaattc aaatttatta ttaggagaag aaaaaggatg aaagcaaaac gattattcct
    57661 attaggcacg attcttttac ttggaggatg ttctactgtc tctcaaaatg aacaaaagaa
    57721 acaagtggat tcaacaactt atgaaactga aacaacaaga aaggaatctt ctacaaaaga
    57781 aatagaaaca actactcaag aaactaaaac aacagagtct tctagtaagg caacgagttc
    57841 agatacgagt gattttcaaa taaaacaaga attatgggat acaaataaag catctcaatt
    57901 agcaactttt gtcccacaat ggggaaagac attaggtcaa gaatataaaa gctacaatcc
    57961 tcagaacaat gtaagtctgt atggtacgcc tttaccaagt gcagttattg atggaaattg
    58021 gaaaatggca atcaatgaag caccagttac tgtacaatgg tcagaagatg gaactggaaa
    58081 tgcaggattt aatttagtag cagtttattc tgatgtagaa actggagaat atttagggca
    58141 gcatgtttac tttttcggtt ttcaaaatgg acaacctaaa gtttatttaa cgcaacaaaa
    58201 tcaaggtaat gaaaataatt atctgtactt taacgaaact caaaatcaac agctaaaaca
    58261 aggatttaca gatatcatta atggacaaac tccccaaaca ccagtagtag aagaatctac
    58321 tcaacaagca acaactacaa cgacacaatc tacaagtagt tcaggaattt caaattggga
    58381 agctgctaaa gaaactgtac taaataataa agcgttatgg atttatgagt ctccagataa
    58441 aaatgaagca aatactaata ttattgaatc cacccaatat agaaaagatt taatgcaaga
    58501 tgaaaatgga gaattttatc cagttgatat ttctactgat gatattggaa atacggtaat
    58561 gaatggagga aaacaattcc gtgtttatac agatggaaga atttctcaac gtattggaat
    58621 gactaacaat tttcaaatga ttaaataatt aaaaatatta tttatcaaag aaaaactgat
    58681 tttgagaaaa attatttaat tttcttagaa tcagtttttt tataatctta attgtcaaat
    58741 taagttagac agatcatcaa tacttacgta actcaaaaat acttccaaag gtgttcgata
    58801 atccagtgat tttctaggaa tattatttcg tttagatgcg acagattgaa taaaaaattc
    58861 atctactgaa ttgaaatcca tagatttcaa taaaccatct ctacgtaaca atccgttaga
    58921 attctcgttt aggcctcttt gagacggcgt tcctggatca gcgaaataaa tggcaatatc
    58981 attgacatta ctgatctgtt tccaatttga aaattccttt ccacaatcaa aagtgatgga
    59041 tttgaatagg tttttcggta cagattcaaa ccattgattt aatttttttt caatatcaat
    59101 cgcttgtcta ccacacggtt tcaatgtgat gataactttt gataatcgtt caactaaggt
    59161 aattacagca cttttatgtt tcagacctac gatagtgtca ccttcaaggt gaccaaactc
    59221 atttgagaat tggctataat ccttttcacg ttcatgaata gagcggcgga aagtttgttt
    59281 tccacgtctt tcttgatgtc cattcggttt acgcttgcct ttcatcggta agtcagaaga
    59341 atcaaatagc ccctttttga acatacgata aatggtacga gcagaacaac taataggaaa
    59401 cgctgcacga ccaacaatca catcgggtgt ccatccttga acaacctttc tttgaatata
    59461 ttctgattgt tcctcgggta aaacaagcgg acgtctacca cagtttgatt tgtttttctt
    59521 atactgttga taatattcta aggctgattt tcctttcttg aagaacagat atactttatg
    59581 gatcgtttgt cttgaacgat tcaagcaatg ggcagtttta gcaacagatt gattaatttt
    59641 gaaataagac tctattatta caagttcatc cgttgtaaga tgggtatagg tcatttgtac
    59701 tcactcctta taattctttg gtcggaacta ttttgagtgt agcacaaatg acttttttag
    59761 ttgtctagct taattttaca atcggcgtaa agtaaaaatg cgaaattaag tagatgagag
    59821 tgatgatgtt cgaaatatct attattttta ataagaatac ataagctatc tagtttgtaa
    59881 acaatgagag aaaaaacatc aatatttttt atcaaaggta tttaaaattt cttctaatgt
    59941 tatagaattt agttatatta aattttagcg gtaggaacgg taaggaggtg aaaacattaa
    60001 gaattaaggg cttttagttt attctttctc tccctgtcta ccggtgaaaa catttaatat
    60061 aaaaaaagga taaagtcgat aaaggcggac tcaatcgata ttaccggtag agagaccagt
    60121 tttttttaag aataaagtgt gaattgacgt atcttttatt cttttttcta gtctaccggt
    60181 aaattttgag aggagcgtca tatgaaattt attatgaata aggagatgta ttaatggcta
    60241 caaattacgc aaaaaagata aattttgatg tggataaact ttataaaagt ttgatagttg
    60301 ttcccaaaaa taaatcagaa gatggaaatt atgaattaga agttttgcaa tttaagattg
    60361 aacaaaagtc cagtgaaaga tttatgagca atcaattagt gaaaatcaaa aaatggctcc
    60421 ctatgattga tcaattagta tctaataata aggaagctaa aaatttatgt atttttgtct
    60481 tattattaca tggaagagtt attaacttag ttaatcgaaa aagtacgact aaatttgcaa
    60541 actcattctg gtttttagaa aatattaatg aaacagtgga aaagaatgga gtttataaag
    60601 gtgattttca ttttcaaaat gctgagacta ttgaacgaga acatcattat ttcgatttat
    60661 tagtgaatac agtggtagaa ttagcgaaat gggcaaagtc aaacgaaact tatagtcaag
    60721 tacttaaaag aattatgagt caagaaactt catttatcta tgagttaagc aagtcaaatt
    60781 tgaaatatac ttataatgaa gatgaacttg aaattttaga taatccagaa aattcacaat
    60841 ggattaaaga gttgaagaga gaagacttta ttgagacact aagaattcta aaatcgttat
    60901 ttgatttgaa attagccaaa gctaccatca tgggaattga aagagattca tattattggg
    60961 aggaaattgg actatatgct ccccagattg aaggtgaaga taaagagaaa aggatagaca
    61021 acattattaa ctatattaat agtttaagtg aacctttaaa atgtagagga cttgatttta
    61081 taggaacatt aggatggaca gaaacatact atgagaaaat atataaagaa ataattgaac
    61141 aatattttcc taaataattt aataaggatt gatttattgt aaaagaaaaa agttgtgatt
    61201 ttggaaatca caactttttt cttttgtcaa gattttgagt gggatatatt tttgtagaac
    61261 tgaagatcat gaaattatga gaggttggag gtaatgtagt catacaaata aaaatttttt
    61321 agaaagtgag tggtaattaa tgaaaatgaa tcacacttca attcagaagc atttacaact
    61381 gttaaataca ctggggattt cttatgttaa tttgagaact ttttctacat taaacaagaa
    61441 aaccgtttct catatttttt ctactgcaga ttctcaagca attattaact atttagaaaa
    61501 acagaaattg tctgaaggta cagtaaacat aacttataat cctattaaac aagaggtgat
    61561 tacacaaaaa aagcattctg tgagagacaa tgatattgaa aaaattcggt ttgtatttat
    61621 tgatattgac cctaaaagga aagagggaag tgcaacagat agcgaaaaga aaaaggcaga
    61681 aaatgttatg gaacaagtag aacgttattt gaaagaaaag agaatagaat catttgtaaa
    61741 agttgatagt gggaatggct accatatttt tcttcccata aatgaacaac caaataatca
    61801 cgagacgatt cttactattc agaattttct tcaattactt caccgaagat ttggagtaga
    61861 agatgaagtt gatattgata cttctgttta taatccttca agattatgca aattagttgg
    61921 tacaccagcg gtcaaaggaa agtccacaaa agagcgtccg catcgtttat ctagtttcct
    61981 ttctattccc gataacatag atagaagtaa ttgttttaaa attcttgaac agatagttga
    62041 agaaaattcc atgatgtcaa cctctagagt aaaaagccat ccatctttta gagaagtgtt
    62101 accttttatt caagcagact ataaacaatg gttagctcac tatcctgaat taacttatac
    62161 cataaaagag ggcgatcata aaggagttac cttacttata tttgacgaat gtccattaag
    62221 aaaacacacg aataattcta atggttcttg tttgtctgtt acggctgata ataagattcg
    62281 atttcattgt ctgcatgctt cggataaaaa taaagatatt caagactttg taaaaaaata
    62341 tccgttgcca aaacctgtaa atccttctgt agaatcatta gaatccaatc aagaatatta
    62401 ttttgaccag tttaaactga atcaagaagg agtatttttg gtgaaagaag gtcaagaaga
    62461 aaaagttgct tgtccgatgt ttattaagca aatacgcaaa aatatcgaac aaaaagtcat
    62521 tacacttgtt cttgcctatt atgtcgatca ttgttgggat gaaatagaaa tagaaggtgg
    62581 atgtttacaa actaataatt ttaaacaatt agcaaaacat ggcttaatca ttaaagctag
    62641 aagagaagct gaagtcgttg actttttaca gattcaacgg gagaatgctc caatcttttt
    62701 tgaacatgaa tctcttggct ggaaaaaaga aaatgaagca atgatttttc agttacaaga
    62761 ttcttttgga cgtgaaattc cttctgtatt aactaaaaac tcatgctacc aattaacaac
    62821 taatggtaca gaagcggaat ttgacgcatt ggttcataag tatgttttag gaacgaactt
    62881 agaacttgct tggtcgattg gtattgcttc tattgtgtta ggctatttaa acgttacgaa
    62941 ggctaatact tttttgagtt tactaattaa cctacagggc aagagcacaa cgggtaaaac
    63001 cactacgtta cactttattg cctctttatt tggaaatcca actacggttc ttagaaatat
    63061 gaatgctacc aataaagcca ttataaagct agcatcaaac aatcagggag gtgttccact
    63121 aatactagat gagttaggag cagcaactca aaataacttt agctcgttga tctatcaatt
    63181 agcttcagga gaagaaaggc taagattaga ttctaattgt cagcttatgc cacaagagac
    63241 tttttctgtt ttgaccctta cctcttctga agagcgtttg gaaaattatt tcaatgagaa
    63301 attaactggt ttgaaagttc gatatatcga attttctgat atcaagttta caaaggatgc
    63361 gaatcacgca gagaaagtta aaagtctttc ttctaatact tttggttggg gtataaagtt
    63421 atttcttttg aaactctttg aacaagggat tgcaaaaatt gaagcaactt ttgtcgaagc
    63481 tcaaaaaaaa atatgggctg ttttacctga acattctttg aagcaacgca ttggtaataa
    63541 tctagctttg atttatagtg gagctctcct aattcaagat atactgggct atcctttacg
    63601 attagagcat atacagacgg tgcttattaa ttcgtacgaa cagttaattg tagatactag
    63661 tttaggaagt gagcaaacgg tatttgaccg agtgaaaacg ttgttggtga tgaatagcca
    63721 taaattttta acaaacagtg acaacaaaca tacgcccagt acgatttggg gaaaagtatc
    63781 aattcaaaaa aatggggata ttaaggtaaa tatttttcct atcccgtttg aggacttgtt
    63841 aaggcgagaa tttcaagtaa aggatctaac ctatcttttt agacaattgc ttgattcggg
    63901 taatatgtgt gcagaaaaag ggagaagaac gaaacgtatt cacatgaatc gtcaagttct
    63961 tccaacatac gagattctat taccttcttc actcaaatcg tattttcgat tgtaatttag
    64021 aataaaccaa agtatgaaag tgaggcacca tgttatggaa atatttctta ttgatttagc
    64081 aaaacaactg attacttatc tgtatgatga cgagcaaacc caaacggaag taaatgaagc
    64141 ttgatctatg cttcatttac ttcattcaat caaacattta agaaagggga attctaatga
    64201 ctaaaaataa aatgacacta aaagcagagg ttcttctgta tattcaagaa catttttcta
    64261 atcaagcctt ttttacaaaa ccaatttact tggctttcga aataagaggg gtatctgctg
    64321 gatctattgg aggtactctt caagcgttga agaacgaagg atatttagaa aatcactttg
    64381 tgcaacgttc gttcaatgga agagtcgcga aagaatggta tttagttcat tcatagagag
    64441 gtgattcaag catgcgtgtg gcttgttatg atcgaacgtc tgtttatgaa gaagcgaaaa
    64501 tcagtaatga cgctcaatat gatgcagtga aagagtatgt tttagagaaa tatgaacaaa
    64561 ttcctcaacg attttcagac aaaggagaat caggtggaaa agcggatcgt ccagcttttc
    64621 gacagcttag agcttgggtt tgtgcgtcag aagaagaggg ggtgatctat gtctggcgtt
    64681 atgatcgatt ggcacgtcaa gccaaaatag ccttagaatt tattgagttg tgccaacaac
    64741 atcaggttca agtttattcg atttctgaac ctcttcctgc ttctttctcg cacgcgtcaa
    64801 cgaataaact atttgtgcaa ttattgttca cttttgcaga acaacaacga aacgtcatta
    64861 ttgaaaatgt tcgtgccgga cttgcctata aaaagcaaca acggcaatat ttgtcttctg
    64921 cggttccata tgggtatcgt ttagtgaatg ggaaaatcca acaagaagca catgaagcaa
    64981 aagttgtccg ccatatcttt caactttatt tgactaaaaa atatggctac aaaaagcttt
    65041 gtcaacgatt gacgcaacaa aagttcttct tccgtgaacg tccttttcag ccctatcata
    65101 tttatagtat cctaaaaaat ccattgtact atggcgaaat caaaggagga tctttgggga
    65161 agtatctagg aacctttgaa ccgattctct cgaaaacaat ctttttacaa gcccaagaga
    65221 ttcgccaatc aaggtgtaca gctaaaaaag atacgtatcc gtacttatta cgtcaaaaaa
    65281 ttcggtgtcc cttctgtggt cgtcatctga gttcgaagta tcaatggaat acaaagaaga
    65341 cgaagacgct tcattattat cattgtaccg accgaagctg ccaaggaatc tttcttcggg
    65401 cagaaagggt tgagtcagaa gtattggaaa agatacaggc tttttttcaa tacgaaggcg
    65461 tctatcaagc cttgattgcc caattgacgc aacaattagc cgaaaagcga aaagatgaaa
    65521 aacacaaagt aatccaacaa aagaaacaag aagcacaatg gctcaaggca tttgaagagg
    65581 gcaattgttc actggaagaa ctcaagcaac agctgcaagc tcttcaaaag ccgaggtcta
    65641 cttcttcgtt tctttcactc caacagtgtg aagcaaaagt gaaagaatgg cttcaactaa
    65701 aagacctctc tagtcgacaa ttgttatgtg accatgtttg tcggatcgag gtaacaaagg
    65761 aaaaaacagt ctgtgggatt tacttccgac aaatgacaca aaatatttta gaagggaacg
    65821 aatgatctat ggaaacgaca ccaaccaaac gagtcgcatt gtatattcgg gtgagtaccc
    65881 aagaacaagc tttagaagga catagtattc aagcacaaga acaaaatgga cgacagtttg
    65941 ccgaacggat gagctatgaa gtggtagaag tttatgccga tgaagggatt agtgggaaat
    66001 ccacaaaaaa tcggttcgcc tatcaacgaa tgatgaacga tgctcggaac catcgttttg
    66061 atctactagt gatttggaaa ttgacccgtc tcggacgcaa tatgttagat gtcttacaaa
    66121 ccgtcgagga actgttgcga tatgatgtgg ggttacattc gatctcggaa caatttgacg
    66181 tgactacttc gacaggaaaa ctaatgttac aactccttgg gagtttcggt gaatttgaac
    66241 gcaaccaaat tgcggagaat gttcagatgt caatgcaaag cttagtgaaa gataaaaagc
    66301 gttatgcagg tggacgacgt ttaggctatg tcagtggtat tgacacgaat ggtcaaaaac
    66361 aattggtcat tgaaccagaa gaggcgaaaa ttgttcgtct gatctatgca aaatatttag
    66421 gcggagcagg gtatcgagcg attgccaatt ttttgaatcg tcaaggatat caaacagtca
    66481 aaaagaatgc tttttctacc acggcagtca aagatatctt acgcaataaa atttatgcag
    66541 ggtatttaga atatgcacgc tatatcaatt gggaaaccaa acgacgaaag ggcaagaacc
    66601 caaaaccgat tttagtgaaa ggtacccatg aaccgattat ttcggaagaa gattatcaaa
    66661 aagtgcaaga acgccttgtt ttagaaggca aacagcccaa atggaaccat acaggtgaaa
    66721 atgtattgac aggcttgtta cgttgtccag aatgtggggc accgatggca gcgagtaatg
    66781 tcacaaatac tctaaaggat ggcacaaaga aacgaattcg gtattattct tgttcagtct
    66841 ttcggaataa aggagcaagt gtgtgtcatg ccaattcgat tcgtgccgaa caagcggaaa
    66901 catttgtcgc cgaccgatta aaggagatcg ttcagctacc agaagttctt ccccgattgg
    66961 tggcagcgtt aaatgaagaa atagtgcgac aaagccaacc attggaacaa gaactcgtgg
    67021 tgttactgga acgaaaggaa gaattgaaga ctaaaattga aaaatgggaa gctgctttgg
    67081 aagatagtcc tgaattgttt ccgatgttaa aagaccgctt agacgaattg actgaaaaac
    67141 gacgacagtt gcacattcga gaaaatgaaa tcttagggat ctttcaacaa caaggagagc
    67201 cgattcaagt caaagatgtc caacggatat tgactagttt ggatcgtttt cttgcccaga
    67261 gtgagaagaa gcaagtcaaa gccttgtatc gtacctttat tgagaaaata acctttgatc
    67321 ctaactataa ggagatattg gagattacaa tgaaattcac gcctgccgtg gtacaacaat
    67381 tgaatgagca atatcaaata gccgtatcca aaacaaagga tacggctatt tttgtgttaa
    67441 agacaccctt tacgttaacg atctagtcta ggttatatca aacaacgtta gaggggcgct
    67501 aacgcttctc tagcgatttg aaatcgttag atgagtcgtt agggaggtcc ttatcataaa
    67561 tagggatatt tattaatgaa tatttgaaat ataattgtat ataagaatta aaaagagtgg
    67621 ggatagatat gaaaaagatg ggtaagtgta ttttatgtga aaaatacact gaacttacta
    67681 aagaacatgt accacctaaa aaatcaggga atactggagg taaaaagacc agaactggta
    67741 atttagatga tttccttaag agcgatttta caaaaggtga ttttccgaag gggattaaaa
    67801 ggaaacctca aggaaatgtt tattatacgt tatgtagtaa atgtaatagt ttttttggta
    67861 gtgagtatgt tgaggaatat attagatttg cagaagacaa taaaaatttc ctttataaca
    67921 atacaagttt aaagaatggt aagtctgatt taacacattc aataaagaaa atgaattcac
    67981 ttagagttgc aaaagcaatt gtagcaatgt tttttagttt aaatggggat gaagattcaa
    68041 tggataagcc attcttagat tcggtacgag aatatcttag caatcctaaa agtactttat
    68101 ttcctcatga agactacaaa attataatga attattatct tccaataggt gctccacaga
    68161 attctaaaat caaaattcct aatgacattg taaatgatgg tgacactcac aatgtaataa
    68221 aaggttttat gccccttgat ctatcaactg ggagaaaaat tcgattttca gaaattcagt
    68281 atgaaggaat tggttttact cttatagatt taaaaaattc aacttttgaa ataaaagaag
    68341 gattagattt aaaaaatctc ctttgtgcag atgataaaat caaaaaaata caattgtaca
    68401 aagtccctat attaacacca acagtactta caatgttgga gatggaaaat aatattaatt
    68461 atattgactc aggttcagat ttgctgatta ggtggcaggt aataactaat tttcttatgg
    68521 aattaaaaaa atacagtaat actcaaacga agttctcttg aagttataaa gaatacaata
    68581 aatataaatt tcctttagac tatattaaaa tcagcaatcg aaggaaaata aacgaagaaa
    68641 atggtacgca aaatctaact attagagcaa aaacaggaag ctgctttgga agatagtccc
    68701 gaattgtttc cgatgttaaa agatcgttta aatgaattga ctgaaaaacg aagacagtta
    68761 caaattcgag agaatgaaat cttagggatc tttcaacaac aaggggaacc gattcaagtc
    68821 aaagatgtcc aacagatatt gactagtttg gattgctttc ttatccagag tgagaagaag
    68881 caagttaaag ctttgtatca cacctttatt gagaaaatca cctttgatcc taatcagaag
    68941 tagatattgc cgatcccgat gagattcaca cctactgtga tttgataatt gaatgagtaa
    69001 tatcaaatag ccgtatccaa accaaaggat atggctattt ttgtgttagg gatatacgtc
    69061 acgtagcttg ttatcaagaa taagtttctt tatttttttg ctttttctaa aactgagtat
    69121 gctaaaataa gagggtatat agcaacttta aataagagat aggagtgtat ctttttgggt
    69181 gcagaattaa atcagaagtt atttagtgcg gcagataatc tccgtagtaa aatggatgcg
    69241 tcagaatata aaaattattt attggggctg attttctata aatatttatc cgaccgtttg
    69301 ttggaacaag tggttctttt agcagatgaa tccttagagg aatatgacac agtaagcaaa
    69361 caaacgatgt tgtatcgtga attactttca gatgaagaat caaaagaaga tctgattgca
    69421 acaatcgttg atattttggg gtatgcgatt tcgccagagt atcttttcaa cgtcttagcg
    69481 gatcaagcaa aacaagcaac gttccaattg aatgatctaa acaaagcctt tttagcaagt
    69541 catatttatg gaaaaatact gtcggcaaaa ttcgaatagt gtcgaggagg tgctgtgatg
    69601 gaagaattaa aagaacgcat tgtcaattat gtcatagaga actctgagat taaaaataaa
    69661 tgggggaaca atacagcaca gaaaatatct gaaaaattaa atgttagtcg taatattgtc
    69721 tctcaatatt tgaatgaatt cgtaaaagat ggagaatttg gaaaaatcaa tactcgtcca
    69781 gtaatcttct tttctttacc ggagaaagtt ccaaatcaac aaatttttag ctcttcagag
    69841 gaagcggaaa aatggtatga tagctctttt agggttggaa tagaaagggt tatcggaagt
    69901 caaggaagtc tgcgaaatgt aattgctcaa attaaagcag caatctacta tccgccaaat
    69961 ggcttaccca ttttacttca tggcgagact ggaactggaa aaagctattt agcaaattat
    70021 gtgtataagg atttgttggc caataattat atagaagaga aggcatcttt catttcagtt
    70081 aattgtagtg aatatgccaa taatccagaa cttttcttgt ccaatttttt tgggcatgta
    70141 aaaggtgcat atacaggagc cgaagatgga agaaagggtt tagcagaatt agctaataat
    70201 ggagtcttat ttttagatga aattcatgca ttgagcaatg aatgtcagga gaaacttttt
    70261 cagtttatgg atacgaggaa atttcatcgg atgggtgata atgaaaactg gtacacatca
    70321 agttgctgga ttatatttgc aacatcagaa ccacctgagg ataaactatt atcaactttg
    70381 ttgagaagaa tacctgtaaa gctaacactt ccaacattag acagtcgttc tctttatgaa
    70441 agaaaacagt taatcaagat attttttaaa tcagaagaag aaagactagc aaagaaaata
    70501 ctgatatctc aacaattatt agatttttta ttaaactatc gctttagtga aaatgttggc
    70561 aatttgaaaa atatcattca attgacctgt gccaatgcct tttatttctt agatgatttg
    70621 gaagaacttt atattcagat gtatcattta ccacaatggg tgaatttcaa cggcatgaag
    70681 gttatgaaaa gacagaatga attaaaatat attcaaatgg atgatttgga aaaagtagac
    70741 gaagttttta atatcaacga acttatagag tatctttatc aaacgtggaa gaaagacact
    70801 gataagcagc agctttttga gaaatatgat agatatttta gacaaaagaa tgttgatatc
    70861 caaaataatt cagctttaac atatcccacc tatcaagaga ttcgatttag acagtatgtt
    70921 aaggaaatag agagagattt tcaaatagaa tttgactatt attatcttca aataacgtct
    70981 atctttttga attcttggat ttatcaaatc caattaacat cggacgataa attatattcc
    71041 ttcatcaatg atattaatag ttggtgtagt cgagaagttc aattagtcaa tcgttttatt
    71101 caaatagggg atatttattt aacaaaaatt caaaaaaatg ttttggttat tttatttaag
    71161 ttaatgtgta gtaaagaatt tcagcaaaaa cgtttagcac tgattttggc tcatggagat
    71221 ctaacggcaa cctgtatagc aagtactgct aataggatcg ttgagagata tatatacgac
    71281 gccattgata tgccactaat gacttcaagt agtgagattg cagacaaaat taatagatac
    71341 ttacaagagt gtaccggata tgaagaaatt attttacttg ttgatatggg ttcactggag
    71401 aaaatttatc taaatttgga actagacgct caaaaaaaat tcggactact aaacaatgtt
    71461 tcaacaagaa tggctattga tgttgcaaat cagatattat tagatttacc gcttaaacag
    71521 attcttgaac aagtaaaaga aaatcaaaat gtggattata tttatgaatc atcaaatatt
    71581 aagaaggata tgattgtctg ttcttgtgca agcggattag gaacttcgtt taaattaaaa
    71641 aagatacttg aagatagctt tccaagggat actgatcttg tcatagaaac gtgtgactat
    71701 tactctttag tgaatgaaaa ctatttatcg gagcttcgta aagagaacaa tattcttttt
    71761 attgttggaa cactaaatcc acatctagaa gatgtagaat tcttttcaat tgaagatatg
    71821 attttaggaa tgaatataag taaattctcc aatcaattga atagacactt taatgataat
    71881 gaactgaaag ttttgaacaa taatattctg aagaatttta gtctaacgaa tttaatggag
    71941 caattgacca tattaaatcc gactaaatta ttagaacggg tttcagatgc tatatacatc
    72001 ttacaaaatg atctaggaat ttcatttgat aataatacgt gtttcggatt atatgttcac
    72061 attagttgct taattgaacg attagtaaaa caaaatactt tggaagatga aatttatttc
    72121 aatgaaacga gtgaggaatt tcaaaaattt cagacacatt ttaagcaatc tttcagtgtc
    72181 gttgaacatt attatagtgt cgacatcccg attcatgagg ttaaatacgt ttatgattat
    72241 gtaaaaagag cttgatttat caagttcttt ttgttttggc atggtaattg cttgtaagaa
    72301 aatgaaagat aaaggaggaa gtatttatga gtattgttat gtcgagagtt gataaccgtt
    72361 tattgcatgg gattattgtc acgcaatggg caccaatgtc taaagcaaac agagtgatgg
    72421 tgatcgatga ttctgtcgca aataacgaca tccaaaaatc aagtatgcgt ttagctagac
    72481 ctgctggaat ggctgtatca attatcactg aagaaacagc gattgcgaat tttaaaaagg
    72541 ggaaatacga tcaggaaaaa gtatttgtca tcgtgaaaga gccggaaaca atccttcatt
    72601 tagtagataa cggtattaga attgaccgac taattgttgg cggtactgtt gttaaagata
    72661 atgcattaca gctatcttct agagcctatg catcagatga aaatatcagc acgtataaaa
    72721 aattgttgga ttctggtgta gaaattgtta cacaatttgt tccggcggat aaggcacagg
    72781 aaattcaatc aaaattagga taaaggagta aggataatgc attttactat ttttcaaatt
    72841 attatgctga ctatattagc atttattaaa catgttgatt attatgggat tccgatgatc
    72901 tttgtaaatt acgcagtttt ttggggatta ttcacaggaa ttttgatggg tgatataaaa
    72961 acaggtttga tagttggcgg tacagttcaa ttgatgtcat taggagttgc cggttttggt
    73021 ggctcatctg taccggacta tggaacgtgc gcaattattg caacggcatt tggtagccag
    73081 cttggagtag aagccggatt agcaatagga ctacctgtag gtatgttagg ggtgcaacta
    73141 gatgtaattg tcaaaatctt aaatggtttt gttgttcgca aatcacagga atatgcgaat
    73201 aaacgagaat ttaagaaaat gaatagtgtt ttgtggttgg ggccaatttt ctttggttta
    73261 tctgcagcaa ttccagtatt tattgccgtt actttaggac agtctgctgt taattacgtt
    73321 ttggatgttt tacctaattg gtttatggat gggctaacat tagccggaaa aatgttgcct
    73381 gctgttggta ttgcgatgtt gttacgcttt atgcctacag gtcgatacat tagttattta
    73441 cttgttggat ttttcttagc cgcttttttg aaggtaccta ttattggagc ggcgatcata
    73501 ggattcgctt tagcatttaa tgtgtatcat agagctgaaa aagatgcaca aatcactgct
    73561 tctgcgggag cttctgatgt tgggtttatt ggggaggatg aataaaatga gcgaaaaata
    73621 tcaagtaacg aaaaaggatc ttaggaaagc gaactatcgt tggttgatgt cagtttgtac
    73681 ctttaattat caaacacagc aaggtgcatc tgtgacttac gcattgtcac ctattttaag
    73741 aaaattatac aaagatgatg atgaatacat cgaagcttta aataatcact ttcagtatta
    73801 caatacacag ccttggctgg cagccattat tttaggtgct tgtgttgcaa tggaggaaaa
    73861 gcaaggatta gaagcaaaag atgcgattaa tgactttaaa gttggtacga tgggtccaat
    73921 tgctggtatt ggggactctc ttttgatgac gatgatccca accatcatgg gatcaattgc
    73981 ggcttatatg gctttagaaa ataatcctgt aggaatcttt ttatggttca ttttaatcat
    74041 ggtaatcttc tttttccgaa tgagaggctt tgaatttggt tataagcagg gaatgaagat
    74101 tgttactgaa tacggtgaaa agattaatta tttaactgaa gctgcttcag tattggggct
    74161 aacagtagtt ggatcattaa ttgcttcagt tatcagtgtt tcaacgccac ttaaattcac
    74221 ttttggtgaa gttagtatga aaatccaacc aatgttggac aaaattttac caacattaat
    74281 tccagtaatt attactgctg cagcatatta tctactcagt aagaaaaaaa tcagtatgac
    74341 cattttgatt ctactcgtta ttgtttttgc gatggttatg gctgcatttg gaatattagc
    74401 gtaaaggaaa aggatttgaa ttatgagaag attgatcatt gctagccatt caatactagc
    74461 tgagggtttt aaagagacac tagagttttt aacaggtatg cataatcaaa ttagtagctt
    74521 atgtgcatat gtcgaagaaa ttgatgatat agatgaacaa attaaagagt tagtggatac
    74581 tacagacgaa ataattgttt taactgacat ggctggagga agtgtaaatc aaaagttttt
    74641 tacctatatt tctgacagag tgcacgtaat tgcaggaatg aatcttccct tggcaatgtc
    74701 aatcgctttg cagttaggaa atgataattt agatattgga gcaattattg cggaggcaca
    74761 acaacaaatc atctatatga ataatcaaaa aagtgaagaa aggatagagg acgaataaaa
    74821 tgaattgttt aaataatata tggctccaca agggagagga aagtagaact atttcaccag
    74881 aaaataaaaa tggtgaaaaa gggaaagcgg caatgacagc gagtcatcta ggaattggga
    74941 gaaaagggtc accttctgtt ccgataaatg ctggagagac aattacttta gcagaaatgg
    75001 aaggccctgg aattttacgt catttttgga tgacagtgac agacaaaaca atcgctggga
    75061 gtttcgtctt acgtgattta attttgcgta tttattggga tgatgaatcc actccttctg
    75121 tagaaagtcc attaggagat tttttttgta atgggtttgg gacaagatgc gaagtgaatt
    75181 ccttaccaat cgtagtgaat ccaacatcag ggatgaattg ctattttgag atgccatttc
    75241 gaaaaaaagc taagattact ttaacgaatg aacatcctga gtttattaag cacatttttt
    75301 atacatttaa ttatgcattg actgaagtac cggatgatgc gatgtatttt catgctaaat
    75361 ggaaccgtga acccatcacg acaaaaggaa aagattacac ccttattgat ggaatcaaag
    75421 gcactgggta ttatgtagga acctactttg ctttgtgcgc attggaaaga tactggtggg
    75481 gggaaggaga atttaagttt tatatagatg gagatgaaga tttccctaca ataacatcta
    75541 caggagcaga agattatttt ggcggcgctt gggctttcca taaaaagaac tttggagaaa
    75601 gggcatatgc tcaaaatttt aatacgctat ttatgggcta tccttttcaa tctaaaagag
    75661 atcacacccg ggattatttt agtgctggaa aacctaatcc aaatccagtt catggttttg
    75721 gcgatgatgc tttaccgatg catgggttgt accgctggca tttacccgac cccattagtt
    75781 tcaaagaaaa tttacgtgtt actttccaaa ccctaggaaa tgatgacatc aagctttatg
    75841 agcgtcaaga cgatatttct tctgttgcct attggtacca aaaggaacca catgagtttt
    75901 tcgaaaaact attagacagg gaagaacgaa ttcctagata aaaggacggt ggagtaagaa
    75961 atgtatggct caatagaagc aggtgggact aaatttgttt gtgccattgg caatgatgat
    76021 ttaaaggttt tagaaagagt gagttttcct acaactacac cgaatgaaac aatgagtttg
    76081 gtaattgatt tctttaatca ctataaagaa caattagaaa gcattggagt agggtcattt
    76141 ggaccgattg atatccatcg tgaatcaaag acctatggac atatcacctc tactccaaaa
    76201 actgcctgga aaaattttga ttttgttgga acgttgaata agcatttcga aattccaatt
    76261 gcctggacaa ccgatgtgaa tgctgcttgt tacggggagt atgtttcagg tcatggaaaa
    76321 ggtttatcca gtgttgttta ttacactgtt ggaactggaa ttggtggagg agctatacaa
    76381 gatgggattt ttgttgaagg gtttagccat ccagaaatgg ggcatacgtt agttaagaga
    76441 cattcaggag atactttctc tggtacttgt ccttttcatc atgattgtct cgaagggttg
    76501 gcatctggac ccgctatcga gatgcgtacg ggaaccaagg gacaagatct ttctatagaa
    76561 gatccgttct gggaaatcga ggcggattat attgcacaat gtgcctgtaa tacgaccctg
    76621 atgctttcac cagatattat aatttttggt ggtggtgtca tgcaacaaga acatctgaaa
    76681 aagaaagtac aaagacgttt tttagaacta attaacggct atgtcgatac gccaaatatc
    76741 gaagaataca ttgtcacacc taagttagca gataatgcag gaactatagg atgcttaact
    76801 ttagcaaaag atgttagaat caattcttaa gcaaaaaagt attagtcaat aaaatgctta
    76861 tgaagtccga tcaacttaat gtggtcggac tatttgtatt cagcaatatc attcactcat
    76921 gatacccagc gccttatcat aagtgatgcg gtttttatca ttgatcctaa aaatcttagc
    76981 aagacaaaaa gtacgtaaga aagtaaagac taaatacttc ggaggaacaa atgaataaca
    77041 atgataggtt attgcgattg cgttatgcga ttgatttgaa agatacggat ttgattaaag
    77101 cttttgagct aggcggtgta ccactgacta aagaagaagc tcaggcggta ctgaccaaag
    77161 tacaggataa gaacaaagat aatgcagaaa ataatgtgta tgaaaaaacc atcaacaacc
    77221 aagtttttga cgcattccta aatggcctga ttctcttggc gcgtggtccg caaaaagata
    77281 agccgatagt agacacgccg caaaaaagca aggaaatcaa atatatcaac aatgtgttgc
    77341 taaaaaaatt aaaaatcgcc ttgtctatga ccactgatga tattttagac gtttttgctg
    77401 aggcagaaat ctatccatca aaaggcgaaa tcggggcatt tttgagaaaa gaaggccaac
    77461 gaaattttaa gccttgcgga gataaatata tgcgtaattt tctcaagggg ttaggaattt
    77521 ataatcggag aaaagtataa agaaatttca tgagaaatca aaacaatggt tgttttgatg
    77581 agagctagtt tttgtatgag attaaaatat tatcttaatc gaggagctgg attggtttta
    77641 tgaatgatga atataagaat gatgaagata agatgctttt tgaagagata gagaatcgat
    77701 gtaggctcaa ttttgagctt cggggaaaga tgtctttaat acaacaaaaa aagtatttag
    77761 cgaataaatc agagtttact ctgggacatg ttgaaaaatt aatctcggat tggattagta
    77821 gtagaagcga atttacaaaa ataaaacagc cgattaaatt tgacatgaaa aaacttttgt
    77881 taaataagag tgagataggt aatagagatc aatatattag agctaaaggg caagaaataa
    77941 ttgattcatt aggtgaaatg aggtcataca attatttgta tgtaacacat agagctgatg
    78001 gaatggtcat tactgtgggg aaatcttctt ctaatgatat ttttttagat ggagatcttt
    78061 tttatcaact caatacaaat cacttgtctg gcactgaaaa tataatttta aggacggaat
    78121 atggcaatga aatatttgca aaatatgatg agattttaaa aaattatttg gactgggctt
    78181 ggataattcc ggttgagtca ggagatgcta agaaactgga gagattattg ggcgatgaac
    78241 taattaataa aaaagtacca attttaaatt attattccca tagacaataa aaggctattt
    78301 ttcatgataa tactagttat aactgtaaaa atggaagaaa atctgggaaa gaagttttta
    78361 aataagtgta ttgttcgatt ttaataaata ataagcaata ccatccgtct gtgttgcgca
    78421 acatcgtact acaatgaata ttttttcaca aaaagaaaat catccatcga atgaatggaa
    78481 ggttttagta tacacgaggt taatgccccc tcttttataa tcagaggagt gaggtttttt
    78541 ctatgaatgt ttctattttc ttattgctag tctagtttct cttacgatga aattgggatt
    78601 ctattccagt ttttattgat ttgctgataa aataacttga atggtggata taaacatgat
    78661 aaataagaga agaataacaa aacaaggttg tgaaatgatt ctcaaatgaa tataatagaa
    78721 agaaaaagga ggaagaatca atgaaaatag caattgcagg cgctggcgca atgggaagtc
    78781 gctttgggtt aatgcttcac caaagtggga acgaagtatt attaatcgat ggctgggcag
    78841 aacatgtcca acaaatcaaa gagcatggat tacaagcaaa ttttaatggt aaagaggtag
    78901 aagcaaaact accaatcgtt cttcaatccg aagtagaaaa agaagatcaa gttgatctga
    78961 ttattctatt taccaaagcg atgcagctgg aaaaaatgct gcaggatatc caatcattaa
    79021 tcaaaaaaga tacagaggtc ttatgtctat taaatggtat cgggcatgaa gatattattg
    79081 agaaatttgt accaatggaa aatatctata ttggaaatac catgtggacg gcaggtcttg
    79141 aaggtcctgg tcaggtcaaa ttatttggaa gtggttcagt agaattacaa aatttaggtg
    79201 atggaaaaga agcagctgca aaaaaattag cagacaaatt gtctgaatca ggattaaatg
    79261 ctcatttttc tgacaatatt cactattcta tttatcgcaa agcatgtgtg aacggaacaa
    79321 tgaacggact atgcacaatc ttagacgtta atatggctga gctaggaaaa acatcgactg
    79381 ctcataaaat ggtggcgacg attgtcaatg agtttgccaa agtagcagca gtagagaaga
    79441 ttgaactaga tgtcccagaa gtcattgcac attgtgaatc ttgttttgac ccggaaacaa
    79501 ttgggttaca ttatccttca atgtatcaag acttgattaa gaaccatcga ttaacagaaa
    79561 tcgattatat caatggcgca atttctagaa aagggaagaa atatggtgtt gcgacgcctt
    79621 attgtgattt cttgactgag cttgtccatg caaaagaaga tagtttgaac gtaaaataaa
    79681 ggagagattg aatggaaact tcacaaaaaa tatcaccgaa aatttttctg aataaagtcc
    79741 tcgctggtac agcaacagga atcattattg gattgattcc taatgcagta ttaggtgcca
    79801 ttttaaaata ttttagtgcg tatccctttg cggtaacgat cgcacagtta gcagttattt
    79861 ttcaactagc aacacctttg atcattggtg gtttgattgc cttacaattt ggatttgatc
    79921 cgatgagaat gatggttgta gccggagctt cttttgttgg ttctggtgta gtcaaattca
    79981 cacctgattt gggtgaaacg ggtgtttacg ttggtgctgg tacaggcgat attattaata
    80041 cgatgctgac agcatcgatt gctgtcgggc tgattttact gattggaaat agttttgggt
    80101 cagtgtcgat tgtgttaaca ccgattgttg taggtgtagg tgcaggttta cttggttttt
    80161 atttattccc ttttgtaaca gcaattactt ctgcaattgg atcattgatt aataacttca
    80221 ctaccttaca accgctgtta atgtctatct tgattggttg ttcctttgcc tttttgatta
    80281 tctctcctat ttcaacagta gcaatcggaa tggcaatcca actagatggt gtttctgctg
    80341 gtgcggctgc gatgggcgta gctgcaacca cttttgtttt agtagtgaac tcttggaagg
    80401 ttaataagtc aggtgtgaca attgcgattg ctttaggcgc tatgaagatg atgatgccta
    80461 atctatttag aaaacctgtg attcttattc cttgtttagt tagtgcagtg attacagcta
    80521 ttcctgtcgc tctattttct atttcaggta cgcctgcttc tgctggtttc ggcgtggtcg
    80581 gacttgttgg tccgttggct tctttagatg cagggctaaa tggctttctt gttgttcttt
    80641 gttggttagt catccctgtt tttgcggcac taattactca atttttatgc gagaaagtat
    80701 ttaaactgta tgatcgagaa gaagtcttca aatttttagg ctagtagatt ttactaagaa
    80761 attttcaatc aatggatgcg taagtgagat gtcaacaaca tctgacttac gtttttttgc
    80821 ctttttgagt aggagattga tgctgacaac tgaactcttc agtgccattc gattttttaa
    80881 aatgtagaag aaactcacct ttatgttatt gattgttcaa aaggcaacta gaataaaaat
    80941 atgtgttaaa atgagaaaaa atttgattgt tggatgtatc gaataatcac taaaaagtag
    81001 gagaagaaaa tgattttttt gcaaaaatat ggtttttatt ttttattatt aggtgtgatt
    81061 agtgatttat cgacaccgta tatccttggc cttttttatc ccaaactgaa tcaaatgact
    81121 accgtaatta gtgtgtttgg tgacgtagat agtccagtca gacgtgcttt cttggtctgg
    81181 tcagttgtat ctggactttt ttttgttctt tcgttgcctg cgttgtatca cctatttatt
    81241 ggaacatcaa aaacacttgc aatacttgct gttgcaacag ttggtttata tgggataggt
    81301 gattgtattt ttactgggtt attcagtatc aatacgaatg aaagctcttg gaatctatcg
    81361 acttggatcc ataatatagg ttctgggcta ggctatgcag gctttctact tttcccattg
    81421 ttacttgttc tgctttatcg tcaaagtggt caaggtacgc ttagccattt ttatcttgtt
    81481 ttaacagtta ttagtttact aattgcaggt ctttacggat tagcacggat tccgtcgatt
    81541 agtcagtttg ccttctttaa gcaattgggc ttctttcaac gcttaagttt tttctttaac
    81601 tatttgccga tgatttgttt aagttttttt caactacgaa agtagaaaaa gcagtgtgaa
    81661 gctgattaag taaaagaatt tctctatggg taaccattcg tgtggatgtg ttcgactaag
    81721 aatagagatg aggagagcga aaagcaagtt agtcttaact tgttatgcgt tgtgctaaat
    81781 ttcaggtagt cattttttga atgaataaga agaaaacttg aaagagggtg acttcatgtt
    81841 agatgtggag cagatggaaa tagaccttta taatattatt ttaaatcgaa atacaagaga
    81901 atgggaaaga acacaatttg aagaggcaaa agaagaccta gcaaaaatgt cgataaagca
    81961 ggtgatagaa aaactagagg tcaacttgcg tccgctagca ctacgagata atttgacacc
    82021 agatgcgatg gatttttatt taagaatcac aggggagtca gcgagtgcaa aggcttatga
    82081 ttatgccaaa cataagataa cttcaccctt ataccaagaa cgggcgattt ttgccggtgg
    82141 ctgtttctgg tgtatggttg agccttttga aacaaaacca ggtgtaatct cagtgttatc
    82201 tggttataca ggtggagaga ccaaaaaacc aaattacgat caagtcagtg gtggatatac
    82261 tgggcatgtt gaagctgttg agatcatatt tgatacacgt caaataacct atgaagagct
    82321 gttggagatt tattggcaaa tttcagaccc tacagatgcc tttggtcaat ttcaagatcg
    82381 ggggaaacaa tatcgttcaa ttctatttgt tgttaatgaa aagcaaaggc aattggctga
    82441 aaaatcaaga gaacaactga ttcaatctaa ccgatttagc cgtcctatcg ttacagagat
    82501 tcgccaagca aagacttttt ggccagctga aaatcatcat caacaatttt atcagaagca
    82561 acctaaaaga tataaaaaga tcaagcattc gcatcagctt catttatttt ttcagcgaca
    82621 tagatagagg aaggttgtgg cgcaaagcgt tcagctccga caaaataatg agcaactgac
    82681 aaaaatagct tttcatattt ttggacagtt atgaattatt tcgaggagtt gctttgagaa
    82741 caccgaggaa aaggttgtgg cgcaaagcat tcagcttcaa gtcgcaagga aacaggaggt
    82801 atgacaagtc ttttgtcaca actcctgttt ttttactagc ctttatttcc atgtgaaaga
    82861 gaattcgaat tgtagaatct tgatttttct atggaatttt gtagagaatc atcttgataa
    82921 ttaatagaca cctaatcgaa ttccacatta atgatgaact aaattccgta taaaagcgca
    82981 aacaataact ata
//
LOCUS       DADGKS010000004        78568 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.004, whole genome shotgun sequence.
ACCESSION   DADGKS010000004 DADGKS010000000
VERSION     DADGKS010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 78568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 78568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..78568
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.004"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(65..730)
                     /locus_tag="JXV47_000250"
     CDS             complement(65..730)
                     /locus_tag="JXV47_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486324.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(877..1482)
                     /gene="dhaL"
                     /locus_tag="JXV47_000251"
     CDS             complement(877..1482)
                     /gene="dhaL"
                     /locus_tag="JXV47_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HAX1486325.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(1510..2493)
                     /gene="dhaK"
                     /locus_tag="JXV47_000252"
     CDS             complement(1510..2493)
                     /gene="dhaK"
                     /locus_tag="JXV47_000252"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HAX1486326.1"
                     /translation="MKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRVVAKNQKAEQ
                     VGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEADSGKGVLLIV
                     KNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAGTVLVHKIVG
                     DAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDEIEYGVGIHG
                     EPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQFVFMNDVLA
                     LLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTISW"
     gene            complement(2495..2890)
                     /gene="dhaM"
                     /locus_tag="JXV47_000253"
     CDS             complement(2495..2890)
                     /gene="dhaM"
                     /locus_tag="JXV47_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HAX1486327.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            3044..3364
                     /locus_tag="JXV47_000254"
     CDS             3044..3364
                     /locus_tag="JXV47_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HAX1486328.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(3476..4345)
                     /locus_tag="JXV47_000255"
     CDS             complement(3476..4345)
                     /locus_tag="JXV47_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAX1486329.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(4441..5745)
                     /locus_tag="JXV47_000256"
     CDS             complement(4441..5745)
                     /locus_tag="JXV47_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAX1486330.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(5742..6251)
                     /locus_tag="JXV47_000257"
     CDS             complement(5742..6251)
                     /locus_tag="JXV47_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486331.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(6426..8561)
                     /locus_tag="JXV47_000258"
     CDS             complement(6426..8561)
                     /locus_tag="JXV47_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAX1486332.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(8644..10299)
                     /locus_tag="JXV47_000259"
     CDS             complement(8644..10299)
                     /locus_tag="JXV47_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAX1486333.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(10301..10615)
                     /locus_tag="JXV47_000260"
     CDS             complement(10301..10615)
                     /locus_tag="JXV47_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAX1486334.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            10785..11045
                     /locus_tag="JXV47_000261"
     CDS             10785..11045
                     /locus_tag="JXV47_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HAX1486335.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            11059..11373
                     /locus_tag="JXV47_000262"
     CDS             11059..11373
                     /locus_tag="JXV47_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur reduction protein DsrE"
                     /protein_id="HAX1486336.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(12103..12657)
                     /locus_tag="JXV47_000263"
     CDS             complement(12103..12657)
                     /locus_tag="JXV47_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HAX1486337.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(12783..14712)
                     /locus_tag="JXV47_000264"
                     /pseudo
     CDS             complement(12783..14712)
                     /locus_tag="JXV47_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(15018..15734)
                     /locus_tag="JXV47_000265"
     CDS             complement(15018..15734)
                     /locus_tag="JXV47_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAX1486338.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(15735..17558)
                     /gene="glpO"
                     /locus_tag="JXV47_000266"
     CDS             complement(15735..17558)
                     /gene="glpO"
                     /locus_tag="JXV47_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HAX1486339.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(17572..19068)
                     /gene="glpK"
                     /locus_tag="JXV47_000267"
     CDS             complement(17572..19068)
                     /gene="glpK"
                     /locus_tag="JXV47_000267"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HAX1486340.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(19204..20664)
                     /locus_tag="JXV47_000268"
     CDS             complement(19204..20664)
                     /locus_tag="JXV47_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAX1486341.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(20654..21949)
                     /locus_tag="JXV47_000269"
     CDS             complement(20654..21949)
                     /locus_tag="JXV47_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAX1486342.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(22281..22958)
                     /locus_tag="JXV47_000270"
     CDS             complement(22281..22958)
                     /locus_tag="JXV47_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HAX1486343.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(22988..24079)
                     /locus_tag="JXV47_000271"
     CDS             complement(22988..24079)
                     /locus_tag="JXV47_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HAX1486344.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(24180..24614)
                     /locus_tag="JXV47_000272"
     CDS             complement(24180..24614)
                     /locus_tag="JXV47_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAX1486345.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(25198..26655)
                     /gene="ascB"
                     /locus_tag="JXV47_000273"
     CDS             complement(25198..26655)
                     /gene="ascB"
                     /locus_tag="JXV47_000273"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAX1486346.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(26652..28547)
                     /locus_tag="JXV47_000274"
     CDS             complement(26652..28547)
                     /locus_tag="JXV47_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1486347.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(28605..30380)
                     /locus_tag="JXV47_000275"
     CDS             complement(28605..30380)
                     /locus_tag="JXV47_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAX1486348.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(30430..31926)
                     /locus_tag="JXV47_000276"
     CDS             complement(30430..31926)
                     /locus_tag="JXV47_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAX1486349.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(32120..33742)
                     /locus_tag="JXV47_000277"
     CDS             complement(32120..33742)
                     /locus_tag="JXV47_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAX1486350.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(34070..35383)
                     /locus_tag="JXV47_000278"
     CDS             complement(34070..35383)
                     /locus_tag="JXV47_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAX1486351.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(35628..35852)
                     /locus_tag="JXV47_000279"
     CDS             complement(35628..35852)
                     /locus_tag="JXV47_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486352.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(35872..36240)
                     /locus_tag="JXV47_000280"
     CDS             complement(35872..36240)
                     /locus_tag="JXV47_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAX1486353.1"
                     /translation="MIQKTRVMLYVNDVEMICRFFVEKIGAEISETIELPEEFKSIVL
                     SISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETIYENMEEPGEITDNNGILT
                     FNFSDPEGNYFVIGKAESSD"
     gene            complement(36436..37146)
                     /locus_tag="JXV47_000281"
     CDS             complement(36436..37146)
                     /locus_tag="JXV47_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486354.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(37164..37661)
                     /locus_tag="JXV47_000282"
     CDS             complement(37164..37661)
                     /locus_tag="JXV47_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1486355.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(37698..38150)
                     /locus_tag="JXV47_000283"
     CDS             complement(37698..38150)
                     /locus_tag="JXV47_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003331879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAX1486356.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(38285..38890)
                     /locus_tag="JXV47_000284"
     CDS             complement(38285..38890)
                     /locus_tag="JXV47_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAX1486357.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(39340..39960)
                     /locus_tag="JXV47_000285"
     CDS             complement(39340..39960)
                     /locus_tag="JXV47_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAX1486358.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(39962..40831)
                     /locus_tag="JXV47_000286"
     CDS             complement(39962..40831)
                     /locus_tag="JXV47_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HAX1486359.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(40854..41261)
                     /locus_tag="JXV47_000287"
     CDS             complement(40854..41261)
                     /locus_tag="JXV47_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAX1486360.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(41280..42569)
                     /locus_tag="JXV47_000288"
     CDS             complement(41280..42569)
                     /locus_tag="JXV47_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1486361.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(42596..42898)
                     /locus_tag="JXV47_000289"
     CDS             complement(42596..42898)
                     /locus_tag="JXV47_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAX1486362.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(42923..45016)
                     /locus_tag="JXV47_000290"
     CDS             complement(42923..45016)
                     /locus_tag="JXV47_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAX1486363.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(45505..46269)
                     /locus_tag="JXV47_000291"
     CDS             complement(45505..46269)
                     /locus_tag="JXV47_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HAX1486364.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(46380..47249)
                     /gene="mdcB"
                     /locus_tag="JXV47_000292"
     CDS             complement(46380..47249)
                     /gene="mdcB"
                     /locus_tag="JXV47_000292"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HAX1486365.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(47274..48350)
                     /locus_tag="JXV47_000293"
     CDS             complement(47274..48350)
                     /locus_tag="JXV47_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HAX1486366.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(48374..48967)
                     /locus_tag="JXV47_000294"
     CDS             complement(48374..48967)
                     /locus_tag="JXV47_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HAX1486367.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(48971..50647)
                     /gene="mdcD"
                     /locus_tag="JXV47_000295"
     CDS             complement(48971..50647)
                     /gene="mdcD"
                     /locus_tag="JXV47_000295"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HAX1486368.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(50637..50936)
                     /locus_tag="JXV47_000296"
     CDS             complement(50637..50936)
                     /locus_tag="JXV47_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HAX1486369.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(51038..52684)
                     /gene="mdcA"
                     /locus_tag="JXV47_000297"
     CDS             complement(51038..52684)
                     /gene="mdcA"
                     /locus_tag="JXV47_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HAX1486370.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(52691..53602)
                     /locus_tag="JXV47_000298"
     CDS             complement(52691..53602)
                     /locus_tag="JXV47_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAX1486371.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            53722..54579
                     /locus_tag="JXV47_000299"
     CDS             53722..54579
                     /locus_tag="JXV47_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAX1486372.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(54766..55128)
                     /locus_tag="JXV47_000300"
     CDS             complement(54766..55128)
                     /locus_tag="JXV47_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486373.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            55474..56913
                     /locus_tag="JXV47_000301"
     CDS             55474..56913
                     /locus_tag="JXV47_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAX1486374.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(56920..59472)
                     /locus_tag="JXV47_000302"
     CDS             complement(56920..59472)
                     /locus_tag="JXV47_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HAX1486375.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(59586..60917)
                     /locus_tag="JXV47_000303"
     CDS             complement(59586..60917)
                     /locus_tag="JXV47_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAX1486376.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(60883..62361)
                     /locus_tag="JXV47_000304"
     CDS             complement(60883..62361)
                     /locus_tag="JXV47_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAX1486377.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(62666..64501)
                     /gene="tdc"
                     /locus_tag="JXV47_000305"
     CDS             complement(62666..64501)
                     /gene="tdc"
                     /locus_tag="JXV47_000305"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAX1486378.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            64971..66398
                     /locus_tag="JXV47_000306"
     CDS             64971..66398
                     /locus_tag="JXV47_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAX1486379.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(66490..66855)
                     /locus_tag="JXV47_000307"
     CDS             complement(66490..66855)
                     /locus_tag="JXV47_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAX1486380.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(66852..67217)
                     /locus_tag="JXV47_000308"
     CDS             complement(66852..67217)
                     /locus_tag="JXV47_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAX1486381.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(67409..67657)
                     /locus_tag="JXV47_000309"
     CDS             complement(67409..67657)
                     /locus_tag="JXV47_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486382.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            67656..67784
                     /locus_tag="JXV47_000310"
     CDS             67656..67784
                     /locus_tag="JXV47_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HAX1486383.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            67841..69535
                     /locus_tag="JXV47_000311"
     CDS             67841..69535
                     /locus_tag="JXV47_000311"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HAX1486384.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            69539..69658
                     /locus_tag="JXV47_000312"
                     /pseudo
     CDS             69539..69658
                     /locus_tag="JXV47_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            69740..69931
                     /locus_tag="JXV47_000313"
     CDS             69740..69931
                     /locus_tag="JXV47_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486385.1"
                     /translation="MDLLPQMQAFEHHLPRGYEKAALHQVIRAAKLKQLLMFLTWLDL
                     LPQMQAFEHRLPRGYEKGV"
     gene            70309..71442
                     /locus_tag="JXV47_000314"
     CDS             70309..71442
                     /locus_tag="JXV47_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HAX1486386.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            71473..71793
                     /locus_tag="JXV47_000315"
     CDS             71473..71793
                     /locus_tag="JXV47_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486387.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(71822..72286)
                     /locus_tag="JXV47_000316"
     CDS             complement(71822..72286)
                     /locus_tag="JXV47_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1486388.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(72417..73670)
                     /locus_tag="JXV47_000317"
     CDS             complement(72417..73670)
                     /locus_tag="JXV47_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1486389.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(73699..74016)
                     /locus_tag="JXV47_000318"
     CDS             complement(73699..74016)
                     /locus_tag="JXV47_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAX1486390.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(74042..74362)
                     /locus_tag="JXV47_000319"
     CDS             complement(74042..74362)
                     /locus_tag="JXV47_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAX1486391.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(74826..76241)
                     /locus_tag="JXV47_000320"
     CDS             complement(74826..76241)
                     /locus_tag="JXV47_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAX1486392.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(76258..77574)
                     /locus_tag="JXV47_000321"
     CDS             complement(76258..77574)
                     /locus_tag="JXV47_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1486393.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(77724..78422)
                     /locus_tag="JXV47_000322"
     CDS             complement(77724..78422)
                     /locus_tag="JXV47_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HAX1486394.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
BASE COUNT        22844 a        16683 c        13342 g        25699 t
ORIGIN      
        1 aaacaaacct tcactcgcaa gccgagagta aggtttgttt ttcgcattgc ttatttcgtg
       61 ttgtctattg aaatttttcc gcacctagct tttgatatag tggtgctagt tcttgtaagg
      121 tttcagcggt tatttgctca acgtgttcga tttcttgcgg atagaagaat agtttaccca
      181 tttgaaaggt tcggtctctc atcgcttttt tcaactcttc ttgtttcttt gtatcggaca
      241 aatagtcaga caaagctaag tggtcgtcaa gttcatgttc tggttgcggc catatgtaat
      301 aatccttgat atcgactgtt ttgctccact ctttcagtat cgcaagcaac tggttatacg
      361 ctgcaatgct accatatcgt tcttcgcttt tataatgttg gtacatcaaa tagatttggt
      421 attgtttttg attcaacaaa actgctagac aggcattctc gtcttgacga gattcgcttc
      481 ggtacgcgct ccaaaaatga ctgcgtaaat tccagccatt cgtccagctt tcgattttag
      541 gtttgctcat gccgtacata tcaggcaaaa gtgcagctgt ctggagctga atctctttcc
      601 atttttgcca gtgttcttta tattctttct tgatttgttc aatcttatct gttggatggc
      661 tctctttgag ctgtttgaat gcgtagattg gtcgatcaaa caactgataa tctgattttc
      721 caagttccat tgtttcgcct ctttccgtta tcttttgtat tctacctgaa ttttgcgata
      781 tggacaaata gaggttgtga aaaagctgtt ctgcatcaag tcataagaac agccaaacaa
      841 aaaactgcga tgagcatcac cgcagtttta ttgaacttaa ggttgattga tcacatctaa
      901 aagcgttgaa aataaaatgg cactagaagc agctcctggg tcgatatgtc cgattgcacg
      961 ctctcctaga taggaagctc gtcctttttt agctaccaag actttggtgt gttcttttgc
     1021 ctggtcaatg atttcttttg ttaaattccc tgccttcaat gcctctgtga ctggcagcca
     1081 aacatctaac atcgttttat cgtcagcttc tgcctttcct cggctttgaa tacccgctgt
     1141 tccctgctcg atcacttcgc ctaatttttc ttgagaatca atagaatcga cctcttttgt
     1201 cgctttcatc atgttcatga atgcagatcc gtataacgga ccagaagccc caccgacttt
     1261 cgatatcatc gccatagaga atactttgaa tgtatcgctg attgtttcag gatgatcggc
     1321 ttgaaaagct tcttcataag ctgaaacccc tcttcccatg ttatttccat ggtctccatc
     1381 gccaatcggg gtatctagat cactgagata ttgtttgttc tgattgattg cctctgcaaa
     1441 ttgcgtgagc cattcttgga tttcttgaac ggttagtttc atattatcac ccttttatct
     1501 tgagattttt taccatgaaa tcgtctgtac attgctttct aaagaatctt tccattgtgt
     1561 ctccgtcaag tcgatcagtg ttagagaaag accttgcata tctagtgagg tcataaaatt
     1621 accgactttt cggaaaacta cattgacgcc tctttcttcc aacagagcta aaacatcatt
     1681 catgaacacg aactgttcca tcaaaggcgt cccgcccatt ccgttgacta gtacacctgc
     1741 ttcttttggt aaattcgagt aatcatctaa aatcttagta acaagttcct ttgccagtac
     1801 tttagaaggc tgcatctttt ctcgacgata gcctggctca ccgtggatac caacaccata
     1861 ctcgatctca tcttctccta gttcgaatcc tggtttccct acttctggta cagttgctgc
     1921 tcgaagcgct agaccgatcg tcttagttgc ctgtacgacc ttttctccca gttctttcaa
     1981 ctcagctagg gaagcaccgt ttcttgctgc atcgcccacg attttgtgta caaggacagt
     2041 acctgcaact ccgcgttttc cagcagtata cgtactattt tcaacggcga tatcatcatc
     2101 tacgatcaca ctttctactt caatatcgtc catagcagct aattcctttg ccatatcgaa
     2161 gttcaatgca tcccctgtat aattcttaac gatcagcaaa actccttttc cactatcggc
     2221 ttccttaata gccgtctgaa tctgatctgg agttggagaa gtaaacacat caccaagcac
     2281 cgctgcactt aacatccctt cccctacaaa cccggcatgg gatggttcat gtccgcttcc
     2341 tccaccagaa accaaaccaa cttgttccgc tttctgattc ttggctacaa cacgggaaga
     2401 ttctacacga tgaacaagtt ctggatagct ttttactaat ccttccagca tttcttcgac
     2461 aatattgctt ggatcattca tgattttttt caatttattc ccatcctttc tttccggcat
     2521 tttgtgcttc tgttaagatt tgctgagtat catctgttat accggcagtg atggctgctg
     2581 caaaagctcc ttccactaaa ggcgcatcca ccagatgata acgttgctgc tgctcttctt
     2641 ccaacatgtc ttttgccagt tccgagttca ataccgcgct accgatatcc gcaaaaacaa
     2701 aataactagc tgcatcgctt gattcattga ctgcttctac gattttcatc gggtctgatc
     2761 cgatctcgcc atttattccg ccgagagaaa aaatttgcac ctcttcggat ttttgcatct
     2821 gctcaatcat ttctttaata ccatctgtta ctttttgact atgagaaata agcaaaatac
     2881 tttttttcac aagaatcttc ctttctttta catagttgct aacgattggt ttcgctttca
     2941 ttaatgaaca attcaagtat ataataaatt tctaattttg ggaaaatatg tgtagtgctt
     3001 cttgaagttt gttatacttt aattaaaaga gaggagtgat cgaatgatta caacaacaac
     3061 gaacagtgta gagggaaaag ccgtagtagc ttataaaggg atcgtttttg gtgaggtcat
     3121 tactgggatc catgcattta aagacttgga ggcggggttg cgaaatatct ttggcggccg
     3181 ctcaaaaagc tatgaaaacg aactaatggg tgcaagagaa gaagcacttg ccgaaatggc
     3241 cgaacgtgca aaagcattag gagctgatgc gatcattggc gtaaaaatgg actatgaagt
     3301 attaggcagc gacaatggca tgctgatggt cacatgtagt ggaacagctg tctccacgag
     3361 ataagtaggg gacatctgtt ttaataacta aagagagatg ggacatgtag tggcactcaa
     3421 gaattagatt tttcagtcta acttcgaggt actctacctt cccatcctct cttttttatt
     3481 tctttttgcg gatgattccg taagctgctg cgactaacac acccgcccct gctaaggaat
     3541 aactgacaga agctgttttt tcatttgttt ttggcaaagt ctgacttgtt gatttggatg
     3601 gctctgtcgt ttgctgaact gtttctgtcg tgcttccaga ggtcactgat ttttctcctg
     3661 ccgaatgcaa aatatctttt attcgttgga aactagctgc taagtcagct ttttttgctt
     3721 caaaatcatt agcaactgtt tgtgcttcgc tgatctttcc gtggattgct tgactggccg
     3781 ctgtgatatc cgcttgagtt tgacttagct ttccagaagc tgtttgagca acctgattta
     3841 attgctgatt gaattctttt gcttgttgga tcttcccgtc aagatctgtt tggacagctt
     3901 ccgcttttgc tttcgcttcg gcaagctttt tctcaagttg tgcacggtca tttcccactt
     3961 tatttttaag atcagctaaa tcttgatcga ttgctgcttg gtcttctttc aatttgtttt
     4021 ttgcagcttc taatgcttct tcgagttctt ttcttttatt ttccaagtct tgcaaatgat
     4081 cgatttggtc agaagaggta gaactattta ttgatgtatc ttctgaagat gaaatcgttt
     4141 ctcctgaatt atctgtcggt acattggaag tcatttctgt ttccgaggca ccgttttcag
     4201 caccagaaga gcttatggtt gttgaaggtt ctgtttgagc aggttcagaa gtttccgcaa
     4261 aagctgtctg tcccaataag aaaatactgg aaacagcaat tggccagatt aacggcttca
     4321 ttcttttttt catcactttt cccatcctta ctacttttta actaatttct tattataagc
     4381 aaaaatgttt ggaagaacca taaacacaac aggctgtttg tctaaaaaac ggtgcatctt
     4441 ttattttttt gtacgttccg ggcttttcca tgtcccgctt ccataaccta aaatcgtttt
     4501 gactgctgga atgaaagtcg tcacgatcgt tatcgcgttc actatccaga acaaaagcat
     4561 atatagtggt gcgaaaagaa ggtatttcaa ttttcttcgt cgatcatcta caatcagcga
     4621 agctagcaac tggaaaaatc ctgcgaccat ttcaaagcag atgaacacaa aactgaatgt
     4681 aaaagtaata taaatctgtt cgtagtttcc ttgatataca taatgcccga ttaatccagc
     4741 aaaaagaact acggaaatac aaaagaatat tgaccagaca atactcaatg tttgatcaat
     4801 gaagatgatc gttcttccaa tatgtttaaa aggatggagc atcacttttt tgaaattcgt
     4861 cagccagact tctgttccac cttttgccca acgttttctg tgtcgatata gcatcttcaa
     4921 cgtcacaggt acttccatga aaaagataat ctcaggagca aaaacagata accagtcatt
     4981 taactgatga tcccaagcaa tactgatgtc ttctgtcgct cgatcttgtc tgaatccgcc
     5041 cacatcgatc aaggcttctt ttcgatacat cgtatttgct ccactgtacg cataaagacc
     5101 accgaaaaca gctgactgtg ttcgtttaat gatgcccacg atacttgaga attcaaccgt
     5161 ttgagatttt gcaatcaatt tggtacgatt ttggacatcc atatttgcag tgaccgcagc
     5221 aatatgtctt gcaccagggc gaatgaaata attcacatac ctaatcagtg catctggctc
     5281 cggtaccgtg tctgcatcat tgcttaaaat caatttccct tttgcaaagg caagtccgat
     5341 attaaacgcg tgggcttttc ctttattttt ttcgatccga accacacgaa gattagcgta
     5401 ttttttcatc agtctagcta atatttctgg tgtttggtcc gttgaaccat cgtctgtcac
     5461 taatacctca tagttgtgat aattcaattt cgtcatcaaa tactcgattg tatattcgat
     5521 cacaatttct tcattatggg ctggcaccat gatcgtgatg aacggttcga cactcaaggg
     5581 aacatctacc cattcttttt gcttatgttt gtataaaaac acataacacc agacaccaat
     5641 aaaccataca aatccgccta aaatcggata agaaacgaga aaaaaataca taatagacaa
     5701 acaagtatct aagaataaat tacctgtatg ggtgattgag atcatttcag ttccacccca
     5761 ttttctttat acaaatctgc aatgaatgtc gtatctagat ttttctcttc ggagacagaa
     5821 taaaaacgga ccgtttctct ctcttctttt gttccaaaac gttccgtata cacttcttca
     5881 agtaattctt gtcttttttt caatttttca tcttcatatt caaaagattt atttactttt
     5941 ttgtatagat ttcgattgtt ccacctagtc aatacaaatg aggtaatcag gaaactgaaa
     6001 aaaatcaata caaaaaagcc gattaagaaa tacagcattt tcttttctga taaaaaagcg
     6061 tacaaggaaa aatccttggc tctttctggt ctcgttaatg ggaaaaagac ccatataaaa
     6121 ggaagaacaa cgatcatcca tcctaaaaga gccactaacg tttgccaaat ctttaaccag
     6181 taattacctt ttgaaaaata cttatctttc accaaaattg atgcaacttc ttctcttgtt
     6241 acttttttca tatcctcacc tcacgttttt ttgttacgac gtaggagttt accatacatt
     6301 tcatttcttt tcacataaag tgttcctaaa tttttcctaa gaaaaagaac aaaacatttc
     6361 tcatcagcaa atgaaaaata ttttgttctt tttatcagtt gttcttttta ttttttatct
     6421 cttaattatg ttgctctttc caatacgaca atgcttttca ttcctctaga tatcgccgtg
     6481 tacatttgtc tgcgtcttct ttgctcatct ccatcgtttt caaatggata taagattaca
     6541 tgatcaaatt ccagtccttt tgctagactc aaaggaatga tttggcagtt ttctaatcca
     6601 tatgaatttt ttttaatcga ttcttgtagc gtttgggttt cctcttctgt ttgggtgata
     6661 actgccgctt tttctccttt tagagaaacc aaaatctcag ctagtatttt caacaattct
     6721 tcagaggatc gaaaagagcg gtattcgggt tcttttcctt gcggtcggat cgatacgatg
     6781 tcgatcttct cttgatccac agcataggtt ttgaaaagct ctgtgattgc tccgctagaa
     6841 cggtaactat ttctaagatc ataccgatgg atcggcagat ggtagtcgtc gaaacaacgc
     6901 ataatatcag caaaagtagt ggaagaatta aagattgcct gattctcgtc acctactaaa
     6961 gtaaagtgag tttttggaaa taattcgatc aatagaccta attgtgccag ggtataatct
     7021 tgtacttcat caatcaatag atagcgaaat gctggtacat ttaccttttc aacaagtaaa
     7081 tgacgaatag ctaatataat gactgcttca tcaacagtac gtgtgggttg ccaagcataa
     7141 gctgagccat atcgtttttc ataaattctt tcaaacaact gatgctcatc cacccatgcc
     7201 atttcttcga tttgtctggt tatttttcga tatttttttt gtaaaagttt ccttgcataa
     7261 gctacaatac tttgttccga atcatcagaa atcaatttac cgaataattc caactgccta
     7321 tcttctgtca acgagagtac ctgattctgc acagcaggac tttttgcttg tttcaaaaga
     7381 tgattcttcc attcgctcat cagtgccttt ttcgttgctt gaagcctatc gatcaattta
     7441 ggatgagcag gaactttctc atatattttt tcgatcgttt ttttagaaag gactgttttt
     7501 ccatttttag taagtccacg gataaaattc ggatgatcta aaaacaaagg atctgattgt
     7561 tttagattat cgataaactt tttgctacgc aaacgttctg tctgctccga tacattttct
     7621 cccgtgatac gtttgaaata agcctcttca ccttctattt cctctgctga aagctgtgaa
     7681 accagctgta tgatggttag attcagtgga tttctttcac ctaatgatgg taggacattc
     7741 gaaatatagt cgataaaccg atgattaggt gatagaatca gcaagtcatc ggatgtcatc
     7801 gtatctcgat ataaatagag cagatacgca atacgctgca tgatagcaga ggttttacca
     7861 cttcctgcta cgccatttac caagatattt tgacttttca catcccgaat gattgtgttt
     7921 tgttccgatt ggatcgtagc agtgatagcc ttcatttcat tggtctcatc ttggcctaag
     7981 acttctaata atacgtcatc ttgaatagct acagacgtat caaaaaactt gaccaaacga
     8041 tctctttcca aaagaaattg tcgtctttct ttaataaccg tatcgatttt attttgacga
     8101 accgtataag aagatggacc aatcatgtta ttgtaaaaaa gttcggcaat tggtgaacgc
     8161 caatcataaa caagattttc atctgcatca tctgtgaaat ttgctgtacc gatataaaag
     8221 gattcttttg gctcattatc cagaaagtct acaacgactt ttccaaagta gggacttttc
     8281 aataaacgtt cgatctttgc tagctgattt tctgcgtttt tctgtttgat attcatctga
     8341 tcgatttctc tatttttcat ttcaatcatc gaaaaagtat ccaggttatc taagtaactg
     8401 tcaaaattca atcgaagctc gccagccatt tctttcaacg actggtttcc ttctattttt
     8461 gccgtatcca tcgattcccg cagttcgttt tttttatcaa ttagcttttg atacacgttc
     8521 ttcagatatg cttcttctaa ctgtttttgt gtgttgacca tacacattct cctctttttt
     8581 taaagtggtg gaaccgatta gtttacctct tttaagagtc gaatgcaagc tttttaacga
     8641 gtatcatttg ttaggatata tcagttcttc aggtcggaca gtttgatata aagaaaatgc
     8701 accatcaagg ttttttacgt ggtagccaga ctgcttcaag attctttccg ctagatagct
     8761 acgtaatccg ctatgacagc tgacgatata ttcttgttgg ctgtctaatt catttaatcg
     8821 gtcccgaagt tcattcaaag ggatatgttt ggcttccttg aatttgccct tttccaattc
     8881 ttctgctgtt cgcacatcta ataaaatttt tccttttgct agttctgtcg gcaattcatg
     8941 ccattgtacg gtttcactaa gcccttctgc aatgttcatt gctgcatatc ctagcatgtt
     9001 tactggatct ttggctgagc caaatggcgg tgcatacgtc aattctaatt ccggtaaatc
     9061 gaagatcgtc aaatgccctt tgattgctgt tgctaaaata tcgatccgtt tatccacacc
     9121 ttttgcccca acaccttgtg caccataaat ctcgccagtc tctggatgga agatcaactt
     9181 cagtaaaata tctgttgctt ctggataata gcttgcatga tcttttcctg atacatgaat
     9241 gacttcaaaa gacagttcgt tttctttggc tgttctttca cttaaaccgg tggatgcggc
     9301 agtcattcca aacgttcgta taattgctgt tccaataccg ccttgatttc ttcgagaaat
     9361 tccggaaatc gtgtccgcaa cttgtctacc ttgacgattg gctggtgaag caagagaaat
     9421 aagtgcatct tttccagtga tttgctgttt tacaacgata gcatccccca ccgcataaat
     9481 atcaggaata ttcgtttgat aacgttcgtc tactaggata cccccgcgta tgcctaattc
     9541 gattccagcg gtcactgcta gctggttatc aggacgaaca ccaatggata aaataactaa
     9601 atcagcaggg atggtacgcc catcatccag tcgcaatcgt ttcccgtggt cttcaaatcc
     9661 agcgacagca tgagaagtaa tcacttctac tccttgatga gacaattctt tttctataaa
     9721 agctgccatt tcttcatcca gtgttggaag aatatgtggt gcttgttcga tcaccatgac
     9781 ttctaaacct cttcttttta ggttttctgc catttccaat ccgatgaatc ctgcaccaac
     9841 gatcacggca cgctttggct gtttttctaa tgcatgcatc actttatcga tatctggtac
     9901 atttctaata gaaaaaacat tgtcggcttc tgttatccct ggaatcgatg gaacaactgg
     9961 ttttgcacca ggagataaaa ccaatgcatc gtactgttca atgtgttttt gaccctcatg
    10021 tacgacttct accgttttgt tttcgggaaa gatggctgtc acttcatgat ttggacgcac
    10081 atctaaacaa aaacgagcgg ataatgattc tggcgtttgg acaagaagat tttcccgttc
    10141 actgatttct cccgaaagat aataaggcaa gccgcaattt gcaaaagaaa catacggtcc
    10201 tttttcaaaa acaacgattt ctgcatcttc cattaatcgg cgaagccgtg tagcagcaga
    10261 cattccacct gctacacctc cgacaataac gattttcatc ttatttccct cctactgttc
    10321 gatcaaacca ttgattcatg ccaccacgta cattcactac atcataacca gatttcttta
    10381 attctttagc tgcttgttta ctcctcatcc ctgattgaca aatcacatag acggtctttt
    10441 ctttgtctcc atcatatctg tttatacttt gtaatggaac atttttagct ccttttatat
    10501 gcccgccccg gtattctgca ggtgttctaa catcaagtaa cgctggattt tccaaaagct
    10561 tttcctttaa ttctgggact gttatcgatt ttattgattg aaatagcaaa ttcattttct
    10621 gcacctcatt tacattttta taaatacctc atggggtata ttaaacagga gctttattaa
    10681 tatgtcaacc agaatgactc ttcatttttt tcactacttt ttatatttgc ataaaatacc
    10741 gataaggggt attatctaat tataaaaata gaggagaatg tgttatggag attgataata
    10801 aaaatatcct gaaccgtttg aaacgtacag agggacaaat tcgtggtatc caaaaaatga
    10861 tcgaagacga aaaagaatgt atggatgtca tcactcaatt aagcgctgtt cgttctagta
    10921 ttgatcgcgt aatgggcatg atcgttgcag ataatctgaa aaattgcttt gagaaacctg
    10981 atagtaatcc agaagaacaa gcggctaaac tagaacaagc gatcaagatg attattaaaa
    11041 agtaaaggaa tgatttcaat gaaagtcgtt ttccatattg atgaattaga aaaatggtca
    11101 gaaacaggga aaaacgtaaa aaacctgata aaagcttctc cagaaacgac gattgtcgta
    11161 tctgtaaatg gcatcgcgat taccggttat ctagactctg ccaatgcaga attcttagat
    11221 ttgcaaggag tcgtttttca cgcttgcgcc aatgctatgc gtgctaatca tatttcagaa
    11281 agttctttac ctgaacaagt aatcgttgta ccagcaggtg tccttgattt agttgaactg
    11341 caatcccaag gttatgctta tatcaagcct tagtcagtag aggttgcgac agaagtgatc
    11401 agcttcaaga aatttcggct tatttttcga agaagctact tctggaaaac cgtgaatcaa
    11461 aggttgtgaa aacgctgtcc tgcatcaagt aataagaaca gccaaacaaa aatagcttct
    11521 catatttttc gtttggttgg gcttattacc gcagatgcaa gcttttgaac accgtttaag
    11581 gaagaggttg tgaaatcagc ggtttgacct aagtattaga gaaaaaaacg ggaaaatagc
    11641 tcctcatatt ttgccgtttt ttgagctaat accgaaggtc agctgattga acaccgttta
    11701 aggaagagat tgtgaaaaag tcgcttagtt tcgagtatta agaaaaattt tgtgaaaatg
    11761 gatttctaca tttttgcata aatttggctt aataccgaga aactggcttt tgaataccgt
    11821 ttaaggaaga ggttgtaaaa tcagcggttt gacctgagta ttagagaaac aaacggaaaa
    11881 atagctgctc atattttgcc gttttttgag ctaataccga aggtcagctg attgaacacc
    11941 gtttaccaag aggttgtgag cctaccattt aactccgaat cacaagaaat aatttcaaaa
    12001 acaacttctc ctgtttttgg ttcggttggc ttattatcga gaagtagcta ctgggagtct
    12061 atttatcaaa aaaaggaatg cgacataggt cacacccctt ttttattttc tttgaaacat
    12121 ctttcggtac tcgacagcat acaagacaaa agattgtaaa agaccgtaag tgatgacggc
    12181 aaaaatgact ctcacccaca gcgttggtaa ttctgggaaa agcagcaaaa ggatcatgcc
    12241 aacatagatg acagcagtcg ctactttgcc ataccacttc gctccactta atttgatatt
    12301 tttagatagc ccgattaatc cagctacaaa cataaagcct tcttttatca agaatagacc
    12361 aaacaacagc caaagccacg gtcgatacca tgccatagac aaaatcagaa aaagttgtgt
    12421 caatttatct gcaaacggat caagcacctt ccctaagtct gttacctgat tatatctccg
    12481 agcaatgacc ccgtctagat aatcagacaa acctgagaca acaatgaccg ctcctgctat
    12541 ataaaatgac tgtctcagca caaaataaag ataaatcggc agcaaaaaaa tacggaatat
    12601 cgataaaaga ttcggaatcg tttgtatttc tttacgccag tctgtgctta atttcatttt
    12661 atcgccctac ctcctcagca ctcttttctt tttattttag cttacacggg gaataaaacc
    12721 aatgatttca ctgtttttat ttttctttac agacactgat attatgagct aatttgagat
    12781 aatcacttgc tgttttcatc gtttactctt ctttcttcct gtcgtttgcg catttctttt
    12841 actagtactt tatgagcttt ttttgatcct cgctctaggt cacgctgccg tttacgtgtt
    12901 ttataatcga taaacagact gtctaaatcg taacctgtcg ggtacagatc ttctgctgaa
    12961 cgcaccagac gaacacgctg acgaggcacg tggattattt ttttgtctaa atatacatca
    13021 atcgtatctt cacctatatc ttcataaact aacgcttctt tttggtattc attgacaaat
    13081 atccgatcac cttttgcaaa gagctgacgt tcttttttat tctccttcct atttgtaact
    13141 gctgtcttag gaagaaattc ttttttctgt gtccgatagg ctttttccgc caagtaacgc
    13201 tctgcttgat ggatcaattt catcgacata tccattttat gagcaatcca caaagcttgg
    13261 ctttctcctg tttcttccaa cccgcaactg atatttagga cgaagtgctt cccgatcgaa
    13321 agccatagca gccggcacaa aatcttcatg atctccggcg aatttcttga tttctccata
    13381 atgggtcgtg gcaatgatca atgccccttg ctcatacata gattccatga ttgcgatcgc
    13441 tagtgcagcc ccttcatttg gctctgttcc actgccaatc tcatctaaaa gtaccaacgt
    13501 attccttttt atctttttca aaatagcagc gatgttttgc atatgaccag aaaatgtact
    13561 caacgcattt tctaaatttt ggtggtcacc gacatcgacg aaaatctcat caaagacagc
    13621 aagctctgtc ccttcttttg ccggaacttg cataccgaac atcgccatca aagtcaataa
    13681 accgactgtc ttcaacacga ctgttttgcc tccggcattt gctccggtga taatcaagcc
    13741 tcgatagtct ttaccgattt caacatccaa tggtaccgca tgctcaggta aaaatggatg
    13801 tctgccttgc ttgataatga tatgttccga tttattgatt ctaggtgtgc ttccattgat
    13861 ttctcggcta aattttgccc gagcaaagat gatatctaac accgtgatcg tttcgatcaa
    13921 taaatcgatc acttcttcgt tttctgcgat agcaccagtc aatgccgcca ggacttgata
    13981 ttcttcactg atttcttcag cttttaacaa ctgatagtgt tcattcaatt tagaaatcac
    14041 agttggttca ataaaaaccg tcgttctttt atttgattca tcgataatcg ttccatctat
    14101 tttattttta tagctggctt tgataggaat cgtatagtat tcgccttttt gaacaatcat
    14161 tgcttcttgg atcatttctt tgtttttcgg atgacgcaag aatttcagta attttgactg
    14221 gatttctttt tcgattagtt gtaattgttt gcgtacttta cgcaaattac gtgacgcgtc
    14281 gtcactgact ttattatttt ttattttctg gtcaatcaac tcttctacat ttatcaaatc
    14341 aggaagatgt ttgctataag caaacaacaa gggtgtctgg tattgattct tatcaaaaaa
    14401 ctttgtgatc atccgactgc ttctaagaaa atccgcatat tcgatcaaat cggttggctg
    14461 cagaatcaac ccttttttga cttgttctgt cagtgcatcg atcctcggca accccataaa
    14521 tggaacatgc tgactgcttt ctaagatcaa gcgtgcttct cttgtttctt cttgacgatc
    14581 caagacagtt tgtaggtttg tcgagaccgt catatcgctg attcgttttt tgctatagtt
    14641 tccaattgct cttgcttgga tttccttttt gatccgatca aattgtaatt gactaatcat
    14701 ttcgttgtcc atattctctc cttttcttga agagatacct gtcccaaaat aaataagggc
    14761 ctagagataa ataaaaggat agaacacagc ttaaaaaagt catgtcctat ccttattaga
    14821 atacaaagat attgttttcc tgacaggtac cgtttcataa gcacaccaaa taaactttgt
    14881 ttattggcta ttcgacttac tgattagata ccagctacac tcacaaaaca taccccattc
    14941 ttctaggtct tatttatttt ccacttaact atagcaagac acattttggt tgtcaaactt
    15001 tagtatgttt tatagattta caccattaat gaatagacac ctaccgcgat aattgctccg
    15061 atcattggac ctgcgattgg tacccatgaa tatgcccaat ctgaagttcc tttattagct
    15121 attggcaata ccgcatgtgc taatcgagga ccaaagtccc gagcagggtt gattgcatat
    15181 cctgttggcc ctcctaatga aagaccgatg gctaagatca atccacctac agcgaatacg
    15241 ttcgttccag gtgcaaattc gttttgtcca aaagctagca acccaagaac taatacaaat
    15301 gtaccaatta attctgtgat cacatttgct ggataattcc gtatagcagg acctgttgca
    15361 aacgttccta aaatcgcgct ttcatctttc gttgcattcc aatgtggcaa ataagaaagc
    15421 caaacaagaa tggcccctgc aaaagctcct aaaacttgcg caatgatgaa aggaacgaca
    15481 agattccaac taattgcccc tgtcatcgcc atagctagag agactgcagg attcaaatga
    15541 gctgggccca tgaatccaga aatatagaca gccattgtta cagcgagtcc ccaaccaaat
    15601 gcgatgacaa tccagccaga agcctgtgct ttacttttgt ttaaattcac agccgcacac
    15661 acaccatctc caagcaaaac taggatcagt gtcccaataa actcccccat gatttgagtc
    15721 atatcactgt tcatttattt ctcccccttt agttcccgca gatctgattc tgcaatcaat
    15781 gcttctaaac gtttagtctg ttgcgccttc tcctcttctg tccattcaaa atatccagca
    15841 attgcatcga tcacaggttg cttgatctca tcaagctgat ctcgttcaaa caacagatga
    15901 tttgtacgac gaatgagata atcgcctggg gccaaaacca tttcttcttc taaaccataa
    15961 cgtaaccgag ctgactcagc gagactcaaa ccaggataag gtgccatttc ttttgctaat
    16021 tcaaagatac gtcgggcatt agtcccgtaa aaatcagcga tataagtagc atcttcttcc
    16081 tctaaaccgg ctgctactcc ttcttttgct aattctgtca ctgtttcttc taatttagtt
    16141 ggatcgaagt ttccacctga aatctgatat tttttagagt cgatttcttt cgtctctatt
    16201 ccgtattctt cttttaataa ttggcgtatc aatcgcaaag ctccttctgc catcttacgg
    16261 taatcggtga ttttcccacc agataaagtc agcaaaccat ctggttctct ttctaaagaa
    16321 ctacctctgg aaatcgtaga aggtgctttt tcatcacggc tgttttccaa atggttcaac
    16381 acgtcttcta cttcagcacg agaaactttg ttttccttat attcacttac tgtatcgaca
    16441 actttattga agctcttgtc tgaaatcgat ccattatctc caccattgta atcagaacca
    16501 gaattaccaa tcaacagtgg acgaagtcct gcccagcttg cttcgatatc attcaatgtg
    16561 atatttgctt ctggatagcg atgattgatc acatccaata gataatctac atcttcttgt
    16621 gtgactttcg gatccgtaaa atctccttgg taatccgtat ctgtcgtacc aaagtaagtc
    16681 ttgttttctc ttggaatagc aaaaaccatc cgcccatctt gctttcctgt atcgaagtat
    16741 gtgggttgcg gtacaggcag ttttttcgca tctacaacta aatggatccc tttagttgga
    16801 cgcattttag gagagactgg acgcgtaaaa ttcaagtttc gtactttatc tacccaagga
    16861 ccactcgtat tgatcactaa ttttgctttg atttcgatca cttcatctgt cagcaggtca
    16921 cgagctttga cgccaacgat ttgatcgcca tcatataaaa agccaaccgc tttcatttta
    16981 cttactagat aagccccatc ttcggcagcc tttttgatat tatcaatcac taaacgggca
    17041 tcattgttgc ggaaatctag atagacaccc gcgcctttta gcccttcttt tttcaaaaac
    17101 ggttctcttt ccaatacttc ttctggtgtc agcgtataat tctcatattt ggttcctgtc
    17161 acatttgcca gtttgtcata aaggtccatt gctactttga ccgagaacat attgaaggtt
    17221 gttgctcctt cgccctcata gattggcaaa agcattggat ctggttttgg gatgtgtggg
    17281 gcaatacttt gtacgactgc acgttcacca actgtgtcag ctactacttc cacatcaaat
    17341 gtcttcagat aacgaatacc gccatgaaca agtttggtcg agcgagagga agtcccttct
    17401 gcaaaatcct gcatttcgat caatcctgtt ttgattcctg atgctgctga ctggactgcc
    17461 acaccggcac cagtgattcc gccaccgatg atcaacagat ccaattcttc ttgctgcatt
    17521 ttttgaatgc tatcttgtct tgtcttgttt gaaaacatat ggatttcctc cttattcaaa
    17581 tgcttgggta gcttttactg cttttttcca accgttgtaa agtttttctc ggcgctcttc
    17641 ctccatttga acttcaaata gcttgccagc ttcataaaat tcgcggatct cgtctgtatc
    17701 tttccaataa ccgacagcta atcctgctaa aaatgctgcc cctagcgccg ttgtttccaa
    17761 gttttctgct cgttggatcg gtacattcaa gatatctgtt tggaattgca tcagatattc
    17821 attgtttgct gcaccgccat ctactttcaa tacaggaatc ttgattccag tgtcatcttg
    17881 catcgtatcg atgatatctc tcacttgata agcaatcgac tgtaaagtag ctttaatgat
    17941 atcttctttt gtcgtaccac gtgtcaagcc aaacatagcc cctcgtgctg cctgatccca
    18001 ataaggagca cctagcccaa cgaatgcagg aacaacataa acctcatctt cgcttgtaga
    18061 gcgtttcgct gcgtcttctg aatcgctagc tttttgcaac atttgaagtc catctctcag
    18121 ccattgaatc gaagaaccag ccacaaaaat acttccttct aaagcatagt aaacctttcc
    18181 atttatgccg taaccaattg tcgtcaataa attatttttg gataattgcg gtttttcacc
    18241 ggtattcatg acaataaatg aacctgtacc ataagtattc ttgaccatgc ctggttcgaa
    18301 tgccatttgt ccgaataatg cggcttgctg gtctcctgcc atccctgaaa ttggtgcttc
    18361 gcttccataa aaatgataac cttgcgtata accataaact tctgagttag aagtgacttt
    18421 tggtaacatc actcgaggaa tatttagtaa atctaaaatc tcctgatccc aatctagctg
    18481 atggatattg aacaacatcg tccgactggc attcgagtaa tcagtaacat gtgcttgtcc
    18541 atcggtcagt ttccatacta accaagaatc gatcgttcca aacatcaatt cgcctttttc
    18601 agctcgttct tgcgcgcctt ctacatgatc aagaatccag cgtatcttcg ttgctgagaa
    18661 ataggcatcg atcactaacc ctgttttttc gtggaaaaat tcttgatagc cttcattttt
    18721 taagttatct gcaattccag ctgactgtct ggattgccaa acaactgcat gatagattgg
    18781 acgtcctgta tctttttccc atattactgt tgtttcacgc tggttcgtta tgccaatccc
    18841 agcaatctga tttggtttga tccctgattc gatgaacgct ccggcaataa ctgactgtac
    18901 agaattccag atttcatttg catcatgttc cacccaactt tcttgcggga aatattgcgt
    18961 gaactctttt tgagaactgc cgatgtgtct tcctttcttg tcaaagataa ttgctcgtga
    19021 gctagttgta ccttggtcaa tcgccatgat atacgttgat tctgtcattg tgattccctc
    19081 cattatatgc aaacgctttc tttaactact cttatcatac tactgtttta aaaaaagaaa
    19141 ctgtcaaaat tttattcttt ttttcttttt ttgacagttt tttattatga agctattttt
    19201 taatcaattc ttttcttttt tcagcgtctc tattcttctt ttcaatcgaa taatgtcgta
    19261 aggtgacgca aattctgaca gataatattc acactgtttt ttgtttctct ggcaaaatgt
    19321 gatcaccaaa tcatattctt taccttcttc ataacttcca atctcaatac cgccgattcc
    19381 cctcagttct ctgatcagat attgttgaaa agcaatacga taaatcggca gactttctaa
    19441 atcgattcca atcactactg gttttgcaat ataaaaatcg atcatcaaaa gaacattggc
    19501 atactggatc atcaggtaac taagctcact atcttcagct cttttcctcg gcaattgctg
    19561 caccgctgtt tcctgtaatt tcgccagtaa ctgtgttaag gaatgcccga gcattttctg
    19621 ctgctgttcc aaaagccgat cacgctcata gacttcgatc tttccaacaa agaaaaacca
    19681 ttcattgttg atctgggaaa tttggtagcc tactgccttt tcttctttga ttttcaaacg
    19741 acgaggacga taatgccata acatcgtttc ccgaatgtaa gtatctaaaa cagcggttgg
    19801 taactttttg ctccgtgtca aatcatactg ataaaatatt tcttcgtcta ctatcgaaaa
    19861 agaaacaaaa aagctgtaaa acatcattgt ttcgtataca ttcagttctg ctgctgttcg
    19921 actaagatgc atcacgatga ttggatcgat tgcttgataa agccggtccg actgatagag
    19981 taatttcttt tctttcaaag ttgcgtacgt acttttttca ttcaatagtc tttttttcgt
    20041 aatcccgagc cagcaagcaa tctgtgcttc tgctgatgcc gtaaacgttg tttctaatac
    20101 acggtccaat cctagaatga acggtctttt ttctggtgta ttttgcaaaa aaagcggtcg
    20161 ctgatcttcc gggatatatt ggaatagttc ataataaaaa tatcgtatct gtagctcttc
    20221 tccgtataat tgaccgtttt tgatttgtaa tccaaattcc tctaagagct ggttcaattc
    20281 tttgatcttt cgaaaaacag aagactcact gatattaaac gctgtcgcta atcgaacgat
    20341 ggatacttgc tgatgttcta ataaatagac gagcatctta aacttcaagc tttcctgcaa
    20401 taaaaacaat agaatttttt ccaaacttac atcttcgtcc aacacaagca gcgcctgata
    20461 ctcatttcgc tgtacttcta cttttttttc catcattcgg ccaatcaatt caatatcttc
    20521 caaatattga tcaaacgagg cttttgacag ttggacatgc tctctcaaac cattgataga
    20581 ggctgttccc ccttgcagaa caaggtttcg caaaatcagg atctgtaact gctcttttct
    20641 ttctaataat gcttcaatct tcataggcag tattcgccac ctttgaccac accatatctg
    20701 gcacacggta ttctggctgg aaaaatagct catgttcttc taactgttca aacgtccatc
    20761 cttcttctac tgcaattgtc agttggtcaa gaaggtggaa catctctttt ttgctttgga
    20821 gctgtgctcc aagaatcttt ttttcagaat caaatagaaa tttgagttta actttgcttt
    20881 gatttattgc tgtaagcttg tagtctacgt atcctgtttc aattttttgg ggataaaaaa
    20941 tgctctcttc ttctgtcaaa cctacgcttc ctaagaaata gccaaaccac tgattgccga
    21001 ctggacgata ggttccctga tcctttgtct gtgagccact aattgtcttg ctgacatttc
    21061 gtgctgtacg gacagcgtta tttactagag aaacatacat tttttcattt gttggacgaa
    21121 aagttacttg gatcgcatcg ccaatcgcat aaacgtcttt ttgagacgtt tgcaagtagt
    21181 catctaccca gatcgttcca tcatcattca atgttaattg ttcttcccac atctgattgt
    21241 cgggacgaga atgattagcc agcaaaacaa gatcatagtt ctcctttctt ttttccgtct
    21301 ctacaatagc ggtttcattt tcggtcaaag acacaacttg ttcttctaaa aaaagtgaaa
    21361 gcccttgatt tttcatttcc tttactaacg gttctgtcat ttcaggatct agataacgaa
    21421 aaagaattga ctttcggctt tcgtaaagat ggatttgttt ttttcttgat gccaaccctt
    21481 cagctatttc gattcctgct tgtcctgcac caataattgc aattttcttt gcattcatga
    21541 tcttttgctg aagagccgtt acgttttgta tctttttaac tgggtgaata agcgttgatt
    21601 ctgcagaaat atttcgaaac ttttgatttg aaccagtcgc tagaatcaaa cgatcaaaat
    21661 ccaatttttt tcctcctgct aaaacgactt ttttttcttt caatcctatt actgtctttt
    21721 ctgtgtaaac atggattcga tagcggtcag tcagttcttc tttcgtgatc caagaaagtt
    21781 gtttttcact ggtaaccttt ccttttaata tcaaattgaa cccgctggga atccatccta
    21841 acttcgattg cttttcaatc aaatatattt cacttgttgg catcaattgg cgaagataaa
    21901 tagccgcatg aatccctgca aacgacccgc cgacaattac aatgttcatc tgcattcctc
    21961 tttcttataa ggtgttctac tgctaacttc tcaatcagaa aacacagtat tcataactcg
    22021 ctttcaacct tatgatacat agcgatgcag cagaatcaac cctctccatc ataccgtgtt
    22081 ctaggtctgc ttctcaataa tgtactagtg gacctaattg aagagtatca tttctgaaga
    22141 gatgtttcaa aaaatgtact cttataaaag aaaaaaactc gccttttacg tacctctgtc
    22201 caaataggaa acagaaaaga acgaaaagac gagttttagc gtgtgtaatg taatagttag
    22261 aatagacaca tcatttattt ttaattcttt aatgcttcaa caactgcttc gcctaattga
    22321 tgagcagatt gaggattttg ccctgtaaga agccgcccat caatttgaac cacttctgaa
    22381 aaagctgctc cagactgata gtttgctcct ttttctttca aagcatcttc tgctaagaat
    22441 ggtacttcat tcgttgtacc atttgcttcc tcttcttcat tactgaaccc agtcactgta
    22501 cgtccagcta aaatagattt tccagactca tctgtaactg gcaacaatcc tacaacaccg
    22561 tgacaaacag ctgagaccag cccttcattt cgatagattt gtgaagcgac tttcccaaga
    22621 tctattgctt ctggaaaatc ccacattgtt ccgtggccac cagcataata aaccgctgca
    22681 taatcatttg catccacatc atcaggacgt aaggtatttc ccaaggcccg atttctgaaa
    22741 tcttcatctt cataataggc ccaatcgatt tcatccatat tcaaaacact ttgcggttct
    22801 aaaggtacat atccgccttt aggactgaca aaatctgcat cgatcccatt ttttactaat
    22861 acatcataaa aatgagtcag ttcacttaac cacaaacctg taggacgctc gatcttttcg
    22921 tacttttcta catttgttaa tacgatcaat actttcattt tcccatcctc tttctataaa
    22981 aattgcgtta ttgataacgt gctttcaaga aattatataa tgggcttggc aaataaagct
    23041 ctttatatgc ttcttcaaaa ggtttcgtta caaattcatc ctcacggttt tccaataatt
    23101 tctctgccca gtcaggatcg acgatcattt gctgtccaat tgctgcaagt tctgcatatt
    23161 tcaatacctg ctctacatct tcgcgattgc ggatcccacc gacaccaact aaagggatct
    23221 ttccttgaat cgtgttatgg accacttcaa gaatcgattt atcgttgtat ttatcagaac
    23281 gagctattcg atcatacata tttaatgaaa catgcagata atctagtttt gactcacgta
    23341 atcgttcaag aagccagatc gtgtcttcaa aacggatacc tggtgtttca tattcttctg
    23401 gtgagaaacg ataccctacg atgaatggtt ttttagcata ttgttcaacc gctgagaaaa
    23461 ccgttgttaa taattcttca ataaaacgat aacgattttc caagctaccg ccccattgat
    23521 cctctcgtct attcgaatgc ggagagaaaa attgttggat caaatacgta tttgctccat
    23581 gcaactcgat tccatcaaat cctgattcaa tcgctctacg tgtggctttg ccaaatgctt
    23641 ggattgtttc aacgatttct tcttcactca ttgctcgtgg tgtttccgca tcaggacgtt
    23701 ttgctgcaac tgcacttgca gatacaggct gttctccaga taaagttgct cgacttgtca
    23761 ttcgtccacc gtggaaaatc tgaataatcg cttttgcgcc ttctccttgg attgctttcg
    23821 ctagctcact taatcgagga atcatttcat catgagcgat gctgagttca cctggccagc
    23881 cttttccgat atcttggaca tttgcagcac cagtaataac agcaccaaga cctttagaac
    23941 gttgtttata ataagtgatc tcatcttcgg tgatcactcc attgaaaaag ctgagttgtg
    24001 tcgtcatagg cgacagcatc aatcggttct tcaattgaac tcctgaaggt aaagtaattg
    24061 attgatcaaa ttgtgacatt gtcattcctc ccataattcg ctctgattaa cctatcgaga
    24121 atcatctatc attaaaccac tcgattagtt gtacatgcaa ctaatttgct taaaaaattt
    24181 tatttttttt gtaacttatc tgttgcatca ttcattgtct gggctaattc tttacttgct
    24241 tcatttccca aaactgcttt gtatgactga tgaagttctt cccagctacc atcgacttcc
    24301 ttagcaaatt ggcgtccttg ttctgtaaga taaactaatg acaagcgacc ttcgctaact
    24361 gttttgacgt atcctttata ttctaatttt tcaacaaaac gagcaatcgt tgatggggcg
    24421 gaatagagca tttgtgcaat atctttttgt ggtattccat ctttttcttt taatatcaat
    24481 aaaataaaac cataagttgg tgccagacct gtccttctaa acgcttcatc agctaattta
    24541 ttcaacatgc gatctagctt tttcacgcta aagaaaagac attcatctaa cgctttttca
    24601 attggctttt ccatttcatc ccctccattg gcgtacatat catagtatga tttttatttt
    24661 ttgtcaaaaa acacggaata atgtccgcct cctctgtcta gatttgaaaa aaagaagtag
    24721 ccatcttcaa agaatttcgg cttgttttcg acaaaactcc ttctggaaca ccgtgaatca
    24781 gaggttgtga aaaagtcgtt tagttttgag tatgaagaaa aattttgtga aaatggcttt
    24841 ccacattttt gcataaattt ggcttaatac cgaaaaactg gcttttgaac accgtttata
    24901 tcagaggttg tgaaaaagcc gtcctgcatc aagtaataag aacagccaaa caaaaatagt
    24961 tcctcatatt ttgtcgtttt ttgagctaat gccgatggtc agctgattgt acaccgttta
    25021 ttgagaggtc gtgagcctgc cgttgaactc cgagtcacaa ggagcaattt caaaaaacag
    25081 cttctcatgt tttatgacta tggtgacttg tgatcgagga gttggcagga gaatactgtt
    25141 tattcgtaaa gaaggggctg tgacaagact tttgtcacag tcccttattt ccttttatta
    25201 taggatttcg ccatttgatt ggatgacttg tctgtaccaa tcaaatgatt ttttctttaa
    25261 ccgtttcttt gtgccattcc cttcgtcatc ttgatcaaca tagatatatc cataacgttt
    25321 tgacatttgt gaagtagaag cgctgacgat atcaatgcag ccccacgacg tataaccaaa
    25381 taaatctact ccatctttga tagcttcctt catctgctca atatgctgct tcaaatagtc
    25441 aatgcggtaa tcgtcttgaa cggttccatc ttcttctact ttgtctatag ctccgagtcc
    25501 gttttcagct atgaacagtg gtttttgata cctatcatat aattgattca aagcaattct
    25561 caaaccctta ggatcaatct gccagcccca ttcacttgat ggaagatacg gatttttaat
    25621 tcctccagtt attaagtttc cttggacccc ttcccaattt tctggatgag cactgactgc
    25681 actagacatg tagtagctaa aagaaacaaa atcaacaggg taggctgcta agatttcttc
    25741 atcacctact tctattttta agttgacacc tttttcttca aacattcgtt gcgtatacgc
    25801 tggataatat cctcttgctt gaacatcact aaagaacaaa gaagttcttt gctgctcaat
    25861 tgttttttga atatcatccg gatcacaaga atacggaaca agaagctgat agctgatcat
    25921 acaaccgact tgtgaacctt tgataatttc atgacaagct tttgtagcta aagcacttgc
    25981 tataaactga tggtgtgcac cttggtattt cgcttgttcc aaatggggat ggttttcttc
    26041 aattactcct acgctaacaa aagggtgatg ttttacacag ttgatctcat tgaaagtcat
    26101 ccaatatttt actttatttt tatagcgttt gaatactgtt tcagcgaaac gaacgtaaaa
    26161 ctgaataagc tttcgattag gccatccacc atattctgta accaaatata acggcatttc
    26221 ataatgggaa agagaaacga ctggctcaat cccatatttt agacattcgt caaacacttg
    26281 atcataaaaa aataatcccg cttcattggg tgtttcttca tcaccatgag gaaaaattct
    26341 tgtccatgcg atagacatcc gatagcattt aaaacccatt tcagcaaata aacggatgtc
    26401 ttctttaaag tgatgataga aatcatttcc gtgtctttta ggataataat acttgctgtt
    26461 gggatcctgc gccgctttta cttgctgatg cgtcatcata tgccattgat ctgtccattt
    26521 ttctttaggt aaatcgctgt cgaatgtata cacatcagac acagataatc ctttttcatc
    26581 tacatcccat gcaccttcac attgattggc cgctgtcgct ccgccccata aaaatccttc
    26641 tggaaatttt ttcatatcga tccccctaaa cttgctagtt ttcttgtttg attatttttc
    26701 ttatgactag taatgatatt tttgaatcta ctactatttg taacaataac cattgtggtc
    26761 ggatcatatc cctctttgat taattcttgc aaatctactt ccatcaataa atcgccttta
    26821 cgtacttttt ttccatcaga tactgcactt tgaaagtatt tgccatttaa attcactgta
    26881 tcaataccga tatggatcag tatctctgct ccttcttcac tgactacccc aattgcatgt
    26941 ttcgttggaa aaactgttga aacttccccg tttacagaac tgtagatttt tccgtccgtt
    27001 ggaatgatcg caaacccttc tcctaaagat ccactagcaa atgttggatc gtttacttca
    27061 gataaatcaa ttatttcacc tgctgcagga gtacttaaca ctatatcctt tgaggattct
    27121 tcttcgattt catccttgta gccgaaaaga aaagttagca tacaggaact gatcatcgct
    27181 aagaaataac tagcaactag ccaaacaaat ccttcaccaa tataaatcgg gaaagacaaa
    27241 atacttcttg tagcaactgc caaagcaccg gctcctgcgg caccagctac tccaccaaat
    27301 atagctccac atatacaagc aatgtaaaat ggtcgtttat atttaagagt cacaccataa
    27361 acagcaggtt cagtgattcc aaataatgct gtgataaatg cagataaaga taaacttttt
    27421 actttcttat ttttcgtttt caaaaatacc ccaagtactg ctcctgcttg cgcagctacg
    27481 gcagtcatac atgctggacc tagcgtatca cgaccgtaga aagaaagatt gttggtcatt
    27541 actggtacaa gtccccaatg taacccaaaa atcactaaca cttgccaaaa tccgccgata
    27601 acagcaccag ataaaacagg gctaaagtta taaacagcta aatatccagc tgcaatcagc
    27661 tgacttgcat aatctgcaat tggacctaca actaataaaa taattgggac catcacgatg
    27721 atacaaatga atggtgtcaa taaatttcga atactttcgt gcaagctttt gcgaatctta
    27781 ggctcaatat aagaaagaac ccatacagct aaaattgctg gaataaccgt acttgtatac
    27841 cttgctagaa tcacgggcat ccctagaaat cgcaaggtta tgctatcact atatgcactg
    27901 acaatcgtag gataaacgag agctgctgca ataaccatag cgatgaaacg atctgtattg
    27961 aacttttttg cagcagtata tgccaaaaat ataggcaaga aatagaaaaa tgcatcagct
    28021 gctgcattca aaatgatata agttcctgat tcagtagtta ataaattcaa actcgtacat
    28081 aaggcgagta ctcctttgat caaaccactt cctgccaaga cgcctaaagt cggggcaaaa
    28141 acagcggcga tcatgtctat aaaagagttt aaaatgcctt ttttctcagt tcctctcttt
    28201 ccactagatg catcatcttc tagtttcatt tgtttggata atacgtcata cacttcattt
    28261 actgcatttc ctactacgac ttgaaacatt cctccagctt cgactacagt gatcacacct
    28321 tctagttgct ctaccttctc cttatctgcc ttcttattat cttttagggt aaagcgtaac
    28381 cttgttgcac aatggtaaac attgctgaca ttttcttcgc ctccgacaaa tcggacaata
    28441 tctttcgcta attgtgaata gtccattttt acttccccct tgttaattaa tgccgtagca
    28501 atccttctta caagataagt atagttctta gaaaacggtt tctccattca attagtaccc
    28561 cttctaatag cgaacgaaac tgtacaatag tgtgtatggt ttacttagcc gagcaaatca
    28621 ctcactgctt gaaagaaaac aagtatatcg tttctcttat agtcaaagga gacaaaaaaa
    28681 acacgcttga tcttcctttg ctgatgtata agtggtatct caagctgata ctctgtgatt
    28741 tttgtttcta cttggctttt gataagacag cacaacaaag tctcggcatt taacggaagc
    28801 ataactaggt cagaactagg agagattagt tgctgaatgg aatctatctt tttatggatt
    28861 tttatttgat tttcttcttt gtagtaatga tcaagcagtt ttgttttctt tttttcttca
    28921 actatggtca gcttttcacg caaaatctga taaatctccc aagattcaaa ctcatctaga
    28981 acactaggta gataaatcaa atcatcccac tcaaaaataa gctcttgctc agtagtcaaa
    29041 attgcatcat attccgttat tttgtttgat tgatttttga aaagatacac tggttctatc
    29101 cggcattctt tgatccacat gttcatactt tgttgaatct gtttttttag tgtattcaaa
    29161 atactaattg gctggttact aacaatcagt atctcccctt gttttcgaaa aggattcaac
    29221 gcttcggcaa gatacaaaac aaaataagcg ctttcagcta aattgggacg taattgaaaa
    29281 tgtattggga agaaacgccg aattaaataa atttctaaag gataacggga gatgatcttt
    29341 tgtacaaaat gattcatggt attatgtccg gcatccatcc tcgttttcat ttgtttgata
    29401 tgggttagca aaaattctgt ttcatggaac aataacgaaa caggaagatc taaaaaacga
    29461 ataatcgttt gctcaaatgc tcttagattc ttctctattt ctttgttttt ttcatcatta
    29521 atcatcaaat aatttaactc taatagtcga ttttcaattg cttgtttttc ttgattggaa
    29581 aaagaatagg gtagttctga tgataacttt tttgtgaggg tctctaccat cggaataaat
    29641 aatgtatacc tgtttgtttt ttctaaaagt tcttctcttc gaagaatggt caaaacgaga
    29701 taccgagaaa atcgtatgaa gtcctctcct gaaacaatat aattatatga tataagaacc
    29761 tcttttaatg tcttttggac agtcggcatg atattggaaa aaattgtact gatttgttga
    29821 ggaaaccttg cgtgttggat caccgtttct gttccaacaa gagataagaa aattcttttt
    29881 gaattttctt cagcaatgat ttttagtcct tttgtcgacg aaacttccag ttctaattta
    29941 ggattgcgct cgatccaacg caaaatcgtt tttatttgta atgatacggc tgtttttgaa
    30001 agaaagaaaa tgtctgctat cttttgcata ctgacatacc ctttttgaaa caataagtac
    30061 gtcacaatag ttgaagctcg gaaatccatg ctggaataga ttttatgttt cgtcacctct
    30121 tgtatgattt gctgtttagt ttcagattca attgattcta aaaaataacc tgaacgttta
    30181 tttgactgga taatgatttt cttctcgtag atagcaagca tatttttgat ttcagtttgg
    30241 atcgttttct tgttggtacc taaagcttca gctaattctt cgcttgttat ccaatgattc
    30301 ttatttctta atactacaag aatttggagt tgtcgtttat ttaagtccat ttgcttacac
    30361 ctcctctttg ttataaacat acaggaaaaa cctctcaaat gacaatagtc acttgcagag
    30421 gtttaaaaat catttgaaga aagatctata ttcaaggttt ttaccattag actggataat
    30481 ttgtttataa tattcaaaac tatctttttt caatctccta aagcttccgc tcccatcatt
    30541 ttgtctatcc acataaataa agccatatcg cttcctcatt tcccctgttc ctgccgatac
    30601 gatatcgatt ggtccccacc ataagtaacc aatgatttgg caaccatctt ttattgcctc
    30661 agcaatttcc tgaagatgta tttttagata ctcacaacgt tttggatcgt ggattcgatt
    30721 caattcatct ggtgcttcat ctagtccaat gccattttca actatgaata atggtaattc
    30781 ataacggtct gtcaattcat tcatgacata acgaaaccct agaggatcaa ttggccaact
    30841 ccaaggttcg ggagattttt ccttcaaaaa gggattatcg aaaccatttg ctccgccagt
    30901 atctacgcgc atttctgctt cttttttata gacagcgcta cgataataac taaatgcaat
    30961 ataatctgcc gtgttagctt gcaagcactg ttcgtctcca tctaacatta ctggtgcaca
    31021 gtcttcttcc ttccatgtcc tgtaaatata agctggataa tgccctcggc acatgacatc
    31081 ggagaaaaac catgaattgc gtttaaattg cagtgaacca aatacattct ctggatcaca
    31141 gtcatatgca taagtcgcta atgcagaaaa gctacacata atacccatct tagcatttgg
    31201 atcgattttc tttaataatt gagtagcacg ggcgttcgct agaaacatat gatgacaggc
    31261 ttgataaatc actttttttg ttagtgtagc aatgggttca agtttatctc tagcagggaa
    31321 tgtaaccaat ccagcagctg cataaggcat acgaaaagca ttattgatct cattaaaggt
    31381 catccaatat ttcactttcc cttggtagcg ttcaaagacg gtctgcgcat aaaattcaaa
    31441 aaagtcgatt aattttcgat tttgccaccc cccatactct cctaccaatg ctaagggggt
    31501 ttcataatga ctaagagtaa ttactggctc gatatcatat cgatttaatg tattgattag
    31561 tctgtcataa aatacgagac cagcctcatt tggcttctgt tcgtctcctc ttggaaatat
    31621 tcgtgcccat gagatgcttg ttcgaaaagc ttttaaacct aactccttca gtaaacgaat
    31681 atcctcttca aatcgatgat aaaaatcaat cgcttcatga gaaagataat ggagtgattc
    31741 gtctaaagca atctcccaaa tctttttttc ttcattccac tgaatactag gatgctggtt
    31801 catgatcccg ataagcgtat ctgtcacatt aggtaatttg ccgtcttcca accatgcacc
    31861 ttcacattga ttagcagcta ctgctccgcc ccataaaaaa ttttctggaa atatttcctg
    31921 atccataact atctctcctc gctatcaaca atttcttact tgaagtatag ctcgattcat
    31981 caaaacaaga tattctaact atttcggcag aagagaagaa aaaaattgaa tgctactctt
    32041 catttttaat atttatatat aacaaataca taagacgatc cccgaaagaa aacactcgtt
    32101 aaccatctaa gcaaacgatt tattttactt ccaacacaaa tgcttcataa ggtcgtaaat
    32161 caactttgcc gtctggtaac tgtttcagag gataatttga cacaataacc cttaaagctt
    32221 cacgtggaat agtgaacgtc tgcttttcac tggacatatt acaaataacg agccattgct
    32281 ggtcttcata tatgcgagaa taggcaaaga catgctcagg cgtcttttcc actaattcat
    32341 agtctcccca gacgatgatg tcatgttttc tacgcaaatc gatcaatttc ttgtacatat
    32401 aaaaaacaga atcttgatct gctaacgctt cttctgcatt gatttcttta taatttggat
    32461 tgactcgaag ccatggaatt ccagtagtaa acccagcatg ttcacgggcg ttccattgca
    32521 taggcgtcct agcattgtct cttcctttcg ccttgattga ttccaagatt tcctcttttg
    32581 taaatccaga agaaatcctt tcgttataca tattgattgt ctcaatatct tttgcttccg
    32641 cgatatcatc gattgggcaa ttcgtcatgc ctaactcttc tccttgatag atataagggg
    32701 tgcctttcat catatggagc aagatagcaa acatcttggc actttctttt cgatacacat
    32761 cgtcatttcc ccaacgagaa acaattcgcg gaagatcgtg attattccaa aataaactat
    32821 tccatccttc atcacctaaa gatgtttgcc atttggataa tacttttttc agttcagaga
    32881 tactcaaggg tttcaaatcc catttgtctt tgccttcttg ctgatctaat cctatgtgtt
    32941 cgaattggaa gaccatggat aattcatttc ttttaggatt ggaataaagt ttagcgattt
    33001 cggtagttgc tccccatgtt tcgccaacag tcatcagatt tttgtcacca aaagttgctt
    33061 gattcatttc ctgaagatac tcatgcagtt taggtccatt acttgtgatt tctttatccg
    33121 gttctttgcc aatcatatcg atcacgtcca tacgaaagcc cccaatacct ttatcgatcc
    33181 agaaattcat catttgataa atctcttggc gaacctgttt atttttccaa ttcaaatcag
    33241 gttgacgctt gctatacaag tgcagaaaat attgccccgt tttttcatcc aactgccaag
    33301 cagaaccact gaatattgag cgcaatctat taggctcttt tccattgacc ggatcacgcc
    33361 aaatataata gtcccgataa ggattttctt tatttttacg ggcctcaatg aaccacggat
    33421 gttcatcaga agtatgattc accaccagat ccatgatgat acggatattt cttttctttg
    33481 cttcttcaat cagttcttcc atttcttcca tcgtaccgaa ttctgccatg attgcttgat
    33541 aattactgat atcataccca ttgtcatcat tcggagactc gtatactgga gaaagccaaa
    33601 ttgcatcaat acctaaatac gccagataat ccaacctgga aataatcccc cgcaaatctc
    33661 caataccatc ttgatttgaa tcttgaaaac ttcttggata gatttgataa acaactgaat
    33721 ggtgccacca tttttgttcc atgattttcc tcctataaat ggatgtttct attttttgct
    33781 taatcattta ttttagtctc tctcactaaa aattgtaacg ctttcaaata gctattgcac
    33841 cttgttatcg gtaacagaat aaaacaaaaa aacagctgag gaaattccct caactgtttt
    33901 ttgaaaggat tgatttatgc agggaagaat gctgatttca caacttcttt ataaacggtg
    33961 ttcactcagc tgtcccttgg tattagctca aaaaacggca aaatataaga aactattttt
    34021 tcgttttttt ctctaatact caggccagaa cgctgatttc acaacctctt tatttcacat
    34081 tcaatatcca catgaatccc acaaatacaa agaacagacc atacatgatt ggagatactt
    34141 cttttcctct tttagctgct aacatggtaa ttggatagaa gataaaacct aatgcaatcc
    34201 catctgaaat actataagtc aaaggcatgc cgatcaagat caagaatgaa gggatcgcaa
    34261 tctctaagtt tccccattcg atttgtcgca aagattgtgc catcaatact cctaccataa
    34321 tcaatgctgg tgcagttact tgtgaagtaa caactgatag taatggagaa aagaacaagc
    34381 ctaacaagaa gaaaatccct gtagtaatag ctgtgatacc tgaacgtcct ccaacggcga
    34441 taccagctga tgattctaca aatgcaccaa caggagaagt accaaataag gaacccgcaa
    34501 gcatagctgt tgaatcagaa gctaaagctt tccctacacg aggcatcttg ttgtctttca
    34561 tgaaacctgc ttggtttgct aatccaacta aagttcctgc tgtatcaaag aaagtcacaa
    34621 gcaagaatgt cagcactacg acccacattt gaagagaatt gatgtcccct acatgtttta
    34681 atgcaactaa aaatgttggt ttcaaacttg gtgctgcggc aacaatttca gaaggcattg
    34741 gaatcaaacc tgtgaccaga cctaaaatcg ttgtagctgc catcccgatg aagatgccac
    34801 ctggtacacg ccgaacaagc aagatagcag ttacgactaa tccaaaaatc gtcaaccaag
    34861 tagaaccaac gttgagtgat cctaatccta ctaatgtaga ttcattcgaa acgatgatcc
    34921 caccttcgct cagaccaagg aaagcgataa atagaccgat accgccagaa atcgcatatt
    34981 tcaaatctgc tgggatcgca tcaatgatca tttcccgcag cttgaagatt gtgatcaaaa
    35041 taaaaatcaa agaagcaacg aatacgccgg ctaatgctgt ttcccatgga atccccattc
    35101 ctaaacaaac agaataagca aaaaaagcat tgatcccaag agcaggtgcc gttccaattg
    35161 gataacgggc taataccccc attaaaacac agccgatcgc actggctaat gcagtcgcag
    35221 taaacactgc tccttcatcc attccagaag cacctaatac agttggattt acaaataaga
    35281 tataagccat tgagataaat gttgtaaatc ctgccagtac ctcacgtttt accgtggtgt
    35341 tcaatttttc tatttcgaag taggaaagta ttttttcctt catcttccat ccccctaaat
    35401 ccgaacatta taaataaagt ccgttaaaat ttcgatttat taataaaaca acgtgtttta
    35461 tcatatacta aaacaaaaca taagtaaaca aaaaattcgg attttaagca aaatccgaac
    35521 gttccatctg attaaatccc tttatctcaa agttcatgaa cattcacttt ggattacaag
    35581 aatttcttta ttgtgttaat aaagtttctt cattctagtc tcaaaaatca atagtgtgat
    35641 ttgattttac catttcgttt ctgttcttct ttgatgaatt cttttgtatc gacaggattc
    35701 agattattta gtccgccaaa acctgtatcg accatttttc cccagccttt tgtcttcttt
    35761 tttcctgatt tgagattctt tgctcgaagc ttctcactat gttttgctcg ccgatacttc
    35821 aaataacctt ctaatcttcc cattagatcc actgtttttc ctccttttta ttcaatcaga
    35881 cgactcagct tttcctataa caaaataatt gccttcaggg tcagaaaaat tgaaagtcaa
    35941 gatgccattg ttatctgtga tttctcctgg ttcttccatg ttctcgtaga tagtttcaaa
    36001 ttcatccgta aaaaatacta aagaaggcgg tggtcctaat acctctggtg aaaacttctg
    36061 cacaaatact tttgggaata cgcctaattc taattctttt gagatgctga gtacaatact
    36121 cttaaattct tctggcaatt cgattgtttc agaaatttct gcaccaattt tttctacaaa
    36181 gaatcggcaa atcatctcta cgtcattgac ataaagcatc acacgtgttt tttgtatcat
    36241 catttgaccc ttctttctat ttgattttct ttcctgtcta taaactgatt ccattatatc
    36301 acgaaagcgc aaacaccttg tgtttgatac tattcaagaa aaataaagca atagtttcta
    36361 ggattgcttt cctccacaaa ctttttttac aaaaaaaaaa cggcaatgaa tgccgctctt
    36421 cttatttcga ttcttttata attctgcttc tgattcatct ttggttagtg tgtgtctaac
    36481 actagttacg ccaaatgttt gatcgatttt ttccttcaac gcttcgattg cctgtgcgcc
    36541 acgtgccgct tgttcagcat tgatggattc aatgaccagc accgctgctt gtgtttcttc
    36601 cgtcagcatc gttctttggg cttcacgcca gttgagacag cgacagatcg ctccttgttc
    36661 atcatagtag atgatttctt ccggaagtgc cggagcatcg gaatctgcac ctaaaggcag
    36721 gaatgattcg ccaccttggg cttttcctaa atgcagattt cctgcgatct tttcgatatc
    36781 ttctccgccg caaggtacgc caaaagacaa ggaaatacta ttatagatat ctacaagcgg
    36841 attgattggg aaaaattccc gttcttgatt tgcacgtttc agtaaagctt caatagaaga
    36901 acgtgcacct tttttagtct tgaatgtggt aaatgcctga cgccactgag caatgacttc
    36961 gttttggctg aatgtttctt ctgtaaggta atttcttgct tcttttgctg cctcattcaa
    37021 taattgatga tacgtttctt cactttcttt tgttacgtgg ttatcgatac catttacgga
    37081 taagatttcg atggttgctt caggaaatac ttcccagaaa ttggtatcca ctattacttt
    37141 tttcatctgt tcacacctct tgattagaat aattgcttga tgaatagata gtctgtttgg
    37201 ggatcatctc ccatataaaa aacatgttcg ctgtatttga taaatccttt tttacgataa
    37261 aaagcgagcg caacatcgtt gtgttcccaa acaccgagcc aaatggctgt tttttgcttt
    37321 tcttttgctt tttcaatagc tgtatctagt aaaaatgtac cgataccttg atgtttaaat
    37381 ttttttcgta catagattcg ctcgatttct aaaaaatgat cagccatttc ctcagattga
    37441 ctcgttcctg tatttagttt caggtaaccc gcaggctctt gatcgatact cactaggaaa
    37501 aaatcggttt ctttatcttt tagctcttct gtaagttttt ctagtgcata agcttgtgtc
    37561 aagtaatcag ctaaatgctc cggtgaatta tcttttccaa atgtatctgt aaatgtttcg
    37621 atactaattt gttgtagtaa gtctacatct gaaggcgtca tttttcgaat ttcgtattta
    37681 ttcacggctt cttcctttca atagatcctt ttattgcctt ttttgacaaa attccaatct
    37741 tcgctaacat tcttgcatac tttatttaaa agatattcca attgttttgc ttcttcgtca
    37801 gaaagaccat ttaatgcgac tgcattggag tagttgtttt ctcgaatgat gaaaggatag
    37861 atttctgctc cttttttagt cggatagagt ttcttgattt ttttattttc tttatcttcc
    37921 aaacgttcga tcatcccatt ggattctaat ttcttgattg ctcgggcagt cgttgtacga
    37981 tctactttga tcatttctgc tagtttttct tggatgattc caggattttc gcaaatacgt
    38041 actaaataaa gatactgtcc tcttgttaaa tcgacttctt tgaattcgat attgctaata
    38101 gaatctagcg ctcgggcaat cattccgatg tctcgaagga tttcagccat ttcatcccac
    38161 ctttattttg tttgtaagac tagttcacct ctttttgttg caaatgcaac tattttcaat
    38221 aaaaaaatca agttcttttt taataactag taaagtatat tcttttcttc ttttacgaaa
    38281 aagctcaatc acaatagatc tggtttttgt tttctaaaat aagtaactgt ttcttcgttg
    38341 ttcgcttttc tgatagcttt ggcaactctt ctatactaaa aaatcccatg ttggaagttt
    38401 cattattctc aataaacttg gcctcttcac cgtggatcgc acaagcaaaa acaagtttat
    38461 aatactgaaa aagctgtgga atatcttttt gtttattcgt atcaaaaact gctcgcaact
    38521 gagtagtttc tactgttaat cctgtttctt catagacttc tttacgcaca ttttcttcag
    38581 gagacaatcc tatttcagca aatccaccag gaagtgacca ttctttcgtc cgtttatctt
    38641 cgattagtag gaccttgcca tcttttttga tataggcacg aacatctact tttggtgttg
    38701 gatgtccttc tccaatcgtt gtgagcgctt ttatttcttc gaaagtttct tttcctattt
    38761 cactgatcag ttccaatgaa atcgtccgga tctcctcaaa acgctcttta tcaaatacat
    38821 cttttccata atatagacca gcttgagaaa gtgcgagtag tcttttgtat tgagccaact
    38881 tcttgttcat tctcttccct tcttttttag caaatgtatg actatgtaat caagtataga
    38941 agactggttt aattacggca aataaatata atgaaatctg caataaataa aagaatgtta
    39001 aaaaactcga gaacaaaaga cattcgactt ctctggggct gtgaataaat ggcgttcaaa
    39061 agcttgcatc tgcggtaata agccccacca aacgaaaaat atgacgagct attcttgtct
    39121 ggctgttctt attaattgag gcaggacagc tttttcacaa cctccccact aaacggtgtt
    39181 ctcctaccaa ctcctcggtc acaagtcaca atattcatca aacatgagaa gctgtttttt
    39241 tgaaattgct ccttgtgact cggagctgaa cgacaggctc acgacctctc ggtaaacagc
    39301 gttcaaaagc caatttttcg atattaagcc atttctttgt tacttattgt cattgatttc
    39361 tttttctaat ttatccaata gtggagtgta atccacttga gtatagtctg ttacatcaaa
    39421 ttcatatagt gttcctaact ggaatttgtc atattttcgg tcggcgatga tctttttgaa
    39481 tgcttctttc gtaatatgat tggtcccttt cgttcgatct tccaatacgt caccatagtg
    39541 ataatgatcc atgatatagc tcaaatgacg atctgattca cgatcacgtt tgtaccgacg
    39601 ttgccataac acttcaaagt ctgctgttag gcgaatcgtg atcacctgat atccgtatct
    39661 atctgctaat tcttggagtc gtgctttttg cttatcacta aaaggatact cggacacaat
    39721 cactttcttt cctgcttcca tatacaaatc aagtgctttg taatagaaag gataaacttt
    39781 cgtcctttct tgttccgccc gttcttccaa attgttaaac ccgatggatt ctgcatagta
    39841 ttccttgatt tcatcgagcg tgatggcata catatctgga aatcgttccc gtagtttatt
    39901 cataagatat gtttttcctg taccaggact accagccaga agaatgaaat actttttcat
    39961 ctcatttatt tcctaagtta attggacttt ccaagttcat aaacagtcca atcttatgct
    40021 tgacaatttc ttttactgct tcatttgctg gaatcacatt atggcgaaga gacttgttga
    40081 tttctgtttc actaaaggtt tctttagcta ctttcgtcca gttgactaaa agctccgttc
    40141 caacattgaa tttgcggatc ccgttattga tcaattcagg ataatcttct tctttcacac
    40201 ctgttcctcc atggataact agggggacat caactactgc atcgatttct ttcagcaagg
    40261 gaatgtttac ttctgttttt gatttgaatt gtccatgatt cgtaccgata gcaatagcta
    40321 atgcatccac gcctgtagct tctacaaatt tcactgcgtc ttccggtctt gtatatacct
    40381 tgtcattttc agcgacatgg attccttctt ctgtaccgcc gattgttcca agttctcctt
    40441 ctacggaaac accgtgcgca tgggcatatt ctactactgc ttttgtcttc aggatatttt
    40501 ctttgaaagg cagatgggac ccatcataca tgacagaagt atatccgctg tcgattgctt
    40561 ctttgatatc atcaaagtct cgggcgtggt ctaagtgcaa gactgcatca accatttctt
    40621 cttctgcaat agctgtcatt acattgacta acacatgcat gccgatatat ttagcggtat
    40681 cgacacttgt ttgaataatg atcggcgaac ccatttcttt tgctgcgcct agcatagcag
    40741 gaagcatttc taggttatgc gtattaaaag ctccaactgt aaaattcaac tcttctgctg
    40801 tttttgttac ttctttcaat gttgtataca tcttttattg ccaccttatc tttttatttg
    40861 tttcctttga tcgttacttg ttttgcaatt tgtcgcatct catccatttt gcccatgtag
    40921 taatcgatcc cttgatcatc accagcacga gcagcatctg cacgcttctg gttatagagg
    40981 ctcatcagtt ttttataccc atctccgatc gtctgtttat tttccaaact cttttctaaa
    41041 tattggatgg cttgatcgtt cacatacaat tcagaaaatt taagtccaac ttgttcataa
    41101 agtttcgcta atttatgctt atcttgggta gtggaaatct cttgtttcaa ttgtgtaatc
    41161 tctgattgaa tcttttcggt cgcttctggc gatagggctt tttcttcttt tgccagaact
    41221 tttttcggtt ctttttcttt tttcttaaaa aatccaaaca tcattttccc tactttcaat
    41281 taaaatgctt tcaaaactgg gcttaagatc caggcatata agagtgctgc ggctactgta
    41341 tctacatcgg ttgctgtagc attgttgaat cccatcgaat taaagatcgt tactagcaaa
    41401 gcgggcaata atgtaataaa gaaaccatga gcaataccgc caatgatcgc tcctcggcgt
    41461 ccgccaactg cgttgccaaa tatccctgct gtccctccgg caaagaaatt ggttagcata
    41521 ccaggtaaaa tcatcgctaa gccgaacatg ggcaaagtaa acatggcaat aatcgtacca
    41581 atcgttgtcg taatgaaacc taaaatgaca gcatttgggc tataaggaaa gaaaactgga
    41641 caatctaagg cagggatcgc atcaggaact aatttcatag ctatccctcg aaatgccggc
    41701 acgatttcac ctaacagtag acgtacacca gctagcaata catacacacc cactacgaat
    41761 tggatggctt gtaaaaaggc aaacatgata tagttttgat ctcctgataa ttcagaagcg
    41821 aatggttcgc ctgcaaataa aacagtgatg atatatagcg ggaccatcac gaccatgaca
    41881 gacaaataag tatcttgcag aaattcgaaa tgtgtcggca acttgatatc ttcgatcgac
    41941 tttttatttt cgcctttctc accaaaaagc ttagcaacac cggcttcaaa taagtacccg
    42001 atcgtacaaa aatgacctaa agcaatatca tttgatccag tgattttacg aatgatcggt
    42061 tgcgctactg ccggcatagc aatggcgaaa caagctccga taaaaccacc gaccaagatc
    42121 aatacgatcc ctcgcagacc ggcaaaatag ccaaagactg tcgtcatcgt tgccatccat
    42181 aaaattgctt gaccagttaa aaaaatgtac ttccattttg tgaaacgagc caaaataata
    42241 ttgaatacaa aaatggctaa gaacgtcagt gcaatatctc tacctaaacc caaatcattc
    42301 attgcttgac cattgataga ttcaatagaa gggatgatcc cttgcatatg aaatccttca
    42361 gtaaagattt tcccgaaata agttaaactt ccaacgatga tgctcgaacc ggcactcaac
    42421 acttgaaatc ctaggagtgt ctttaacgtg ccagagatga cttgtcctgc tgatttcttc
    42481 tgcagtagta gacccaacat agcaatcaat gcaatggtga tcgatgcctg agtcaaaata
    42541 ttttcgatga taaaattgat aacgcccatg tttttaccct cttttctttt tgtatttaga
    42601 taactccctt atcttgcaga actggggtga ttttttcttc aatttcattt tttgaaacaa
    42661 tatttttcaa atagatcatc gccgttttag gatcaactgc gaacttttcg aactgcgaac
    42721 gaaaattttc tgctgtgatg atcacatctg gtttcatgga aactgcggaa gaaatatcac
    42781 aatggtccag tttggcttct actcctaatt tgttcaaaac atcctcagca gacatctgtg
    42841 ctgcaaaact acttcctaaa cctgcaccgc atacgaataa aatgttcaat ttgttcatct
    42901 ttgttctccc ccgtatcatt tattatttct caactactga aaaaagcagt tgtttgaaat
    42961 cttcgatatt tgtgcattca atcaatcgat ccaacttctc ttcgttgttg atcaattcaa
    43021 ttagttcttt catgatgttc agatgcgagt aggagtctac tgctgccaaa caaaaaataa
    43081 tctttactgg atccatttca ggattaccga aatcgattgg ttgctcaatc gtagctacgc
    43141 tgactcctaa tttattgacc ccatcttctg gtcgggcatg ggctagtgcc atgtgtttgc
    43201 caatcacgat atacggtccg taatcattca ctgcacgaat catcgcttcg acatagcgct
    43261 cttcgacaat gttttcttta accaatggtc tagcagctag ttcaatcgat tcctcccaag
    43321 tagtggcttt ttctttgatc atgatattgc tgtccgtcaa aatatctttt aacataggct
    43381 ggatctccct tttgttgatt tctaaattgt ttgtttcgaa taatttttct aacttgccat
    43441 agatgattcg atctactcgg ccaccacttt ctttcatgac atctattatt tgagtgaata
    43501 actccgtcga ttcatgactg ttaggctcta accgctgtag ttcttcattt cttttcaaaa
    43561 agtcttctat aaccaagata ttcgtctcag ttaaaatcgg atcgacaact aaaagcggct
    43621 tatttcgata attcaattga aaggtgctga aaaccagatt gacatccaat ttatctacta
    43681 attcgatttc ttttgaactt aaaactgcag taatctcgat ctgaggaaac ttttctttca
    43741 gattctctgc taacagattt ccagtagcca tcccatggtt acagacaacg actgatttat
    43801 aaacataatt caagtctcgc ttgattacac tggcgatcgt cgaaaagtgg atgacaagaa
    43861 aagctatctc gtcctccagt atcttgccac caattacttc ttcgatcgta ggaacaaaat
    43921 gagtgactgc gcggtagatt gggaaataat ttgttcggat gttttctttc aatggattca
    43981 tgacttggat atgattcttg attcttacaa tcagtgcagc catgtgctta tagagatttt
    44041 cgaataaagc ttcttccttt agatggaaag gtacgtgtgt ctcgttctct acaaattgga
    44101 tcaattggat cgttagtaat tgagcttgta cccactcgat tgaattggag atatctctag
    44161 cattgaacgt ctcaatagtg aaacgaagat aatttctttc tacttgcggg acattgtcca
    44221 attgaaattc ctcgatcatg tggtcaataa atgcagaaaa gctactgtct tttatttctg
    44281 tatttttcca attaatggca gagataaatt catgtttcct gattcgctgg atccagatca
    44341 atgtaaaaag caggatttgt tttttataaa tatcatcttc ttgtttcaac aacttattgg
    44401 aatagatctc ctgtattttt ttgatttcca ccaaaggaaa ataatggaga aagatttttt
    44461 gagccggtgt taattgtgca tcttgattca taaagaagtc ggtcattccc agattctgat
    44521 tgataaaatc atagatcatc gtacggatag atcgttctga acctttataa accagtcctt
    44581 gctttccata actgacgatc tctatcccat aactgaccag tgttgctcgt aaccgtctca
    44641 tatcttcatc taatgtactt ttagagattt gaaattcttc ttcttttttg tttagatgga
    44701 tcgggattcg gctgtaagca acggctaaaa ctagatcaaa aatacgttcg cgccgattca
    44761 aaaagccgtc tttcacatct tttatttcag tttctaatcg agcttgcttt tccttttcca
    44821 gcttcaacaa aaaacctttg ttgcgaattg tacggatctc cggaagcttt ttactgctca
    44881 accagatatt cgcttcaaga acttcctgac ggatcgtccg ctgactgaca ttgaactcac
    44941 ttgctagatg ttttgctttt actggatatt gggctgtcat gattctgtga agtatttcaa
    45001 ttgttcttgt tttcatagaa atgatctcct tctgatttca agtatatggt tccgcttaca
    45061 taataaaaag tagatatttc tgccacttga agtggaaaga aagtaagcaa agcaaacaaa
    45121 aaataagcca tatgcttttt catctcctca acgaaaaaga catacgccta ttattacaaa
    45181 aattttgccc atctatacaa aaaagaggtt gtgaaaaagc tgtcctgcat caagtaataa
    45241 gaacaactaa actaaaatag tgcttcctat ttttcgtttg gttgttctta ttatcgcaga
    45301 tgcaagcttt taaacaccat ttagtggaga ggttgtgaca gagatgttca gccttgagcg
    45361 ataagaagcg attttgaaaa atcgcttccc atattttaca aaatcgtgcc ttattgccga
    45421 taggctatct ctggcacacc gtttattcag aaaaaggagc tgcgacaagg cttttgtcac
    45481 aactccgttc ataaatattt cctgtcaatc cagcataatc ggctgaataa aatcggcttg
    45541 ccatcttttt tctttctcag aaaaatcaaa ataccatatc tgagaaaaat actgtcgttg
    45601 tgtcttactt cctgagatca atcgcccatc ttttcgatcg actgaataat cacagcatct
    45661 gaaatcaatt cggatggcaa aactattttc gtggatctgt cgataatttc ctacttcctg
    45721 aatagttatt tttttagtat gatttcttac accgtctgct ttgttttttt gcagaacttt
    45781 ctgatgttcg gcaaacagct tgtctgtata acagcttctg gctttttcag gagtttcttc
    45841 ttcccaagcg gattggatct tcatgaatat cttttggatt tccagaaact gtgctttctt
    45901 ttctttagcc gttcctgaca tgcgggacaa tatctccgct ttcagccttt tcttttgtct
    45961 tttattcttg acgatagaaa aagcagaaac ccctcctact gacaaaacag ctaatgcaag
    46021 aaatcccgtt tgctcataac tagaaggacc tgtacctgga ccataatacc cataagaatc
    46081 tctgccgtaa gaacgactgc caaaataact gcccccatat gaacgaccac caaatgaacc
    46141 tctgcccgaa cttcgaccgc tagatgtacc tccaccatga ccacccgcga cagcgaatcc
    46201 ttgggtcggc agagcaaaca aacataggcc cactaacaaa atgattgcta aataattgat
    46261 ttttttcatt gtcttcctcg ttatctttta ttacaaaaaa ctatttttat gatagccttg
    46321 ctaaaaggaa gagtcaataa ccagatgcat aaactgtttt tttagcaatt ttgtcttatt
    46381 tagtcattga gtaacatcgg acaaatgtat gtgtcggcag tccataattc ctctatcttc
    46441 agcatgaaca agcttgcaga caagagatct gcgcttcctc caggagagat ttggttttcc
    46501 tgacaaaagt gcaacagtgc tgtaaatgga cgatttggta aagcactttg actagcagca
    46561 tgagcaagtt tttgcatttc cactaacgtt ttctgatcac tgcgatgcaa tacgcatgtg
    46621 tcatctagcg aactcatcaa aactaacaac atatgcattt gtttctgtac atatgaatca
    46681 ttatctagct ccttagctgc ttgaattgca agcctgatat gcggataccc taatatcgct
    46741 tcttcatatg caccatttac gccatatttt tgcttcaccc tatgaccatg agtggttttt
    46801 ttatgacgat attttgtatc aggaaaagca gcaagcttgc tgacatcatc aagtattttc
    46861 gataaagaaa aaggctgttc catactgatt ttttgtgcaa tgacactgat caatagcccc
    46921 attgcccaaa tcgctccttt atgggtattg atgccatttg tagcaatcag cattgccttt
    46981 tccgcttttc gcccaatctc agcaattctt tctcttaact cctgatcaat agcatgatgc
    47041 catgctattt gagccatttc ttcaaaaaaa ggagttagcg tcttagcaga cttaagaaat
    47101 aaagcatagt ccatatcgga atgtgcaccc gcatccagtg catccactaa tccaggtttt
    47161 ggacttaatg ttacttctgc gatcaatgct tcctctacca acgcagcgag ttgctgagtc
    47221 actgcttttt ttcgttcgtc atttatcatg acactcactc cttcttccta ctattacttg
    47281 ctgaaacctt ttttgatagc tacccaaatg atatgaagta accagcttaa agcaaatgca
    47341 caacttgccg tcattagata agctacaaga atcatgactc ctgaaggtaa ctgcagccaa
    47401 ctatctttaa acaataataa cagtacttgg aaaacaaata cattggctaa atacgtacga
    47461 taagcataaa cagacaacca tttgaacaat ggcaattttg gcgaatcgtt tacaatcatt
    47521 ttggaagcgc ctatgaagac agcaaagatg atgactaaac tgtataaact ttggatcgta
    47581 ttcaagtaag gtgcattcgc aaagctcaag tctcctggat gtgcgagcaa tgaacggaca
    47641 gaaaagaacg cgataactaa ggcaacaggt aagaaaagat aacgtactct gtccaaatat
    47701 tgatagactt tttcgtgata aacaaatgcg gctaccccat aaatcatgaa actagcaaca
    47761 aaccgatcta ataagtacca gctgtcatga taaggcccag tcaatacttg tgtttgatag
    47821 aacagatacc atgcgacata taaaatcgtt gaaccaatca atactggcca tacatatttt
    47881 ttattagcaa atactttgta accgagccaa acaaaaaacg gcatgaacaa ttggatctgc
    47941 agcatcataa cggtatacca taaatgaggc gctccatcac ctgtgacata tttcagtaaa
    48001 aagcttgcag tatccgtata cggagtttgt tgttggactg ctggaaatag ccaaagataa
    48061 gccgtcgtcc atagaagata cggaacgact agttcaaaaa acttttcttt caaaaattcc
    48121 caataagaca aatgctgact tgtttttacc atattataaa caattgcaaa aataaacatt
    48181 ggtgctgtgt atttaacgat gacgtaaaag gtaccaagaa aagctgtatt tgttgcgctg
    48241 tggctgtttg ccaaagcaaa gctcaatatc gtttgcatca taacagccgt tacagctgat
    48301 actttctgga agtcacttac gttgattttg atttttttgt tttcaaacat ctctttctct
    48361 ctctttttct ttattaccaa agttctttgg ttaatttagg tccttcgact gttttcaata
    48421 gaattttttt ctctggctct ctcaaatact cttttagtga aaaaccgcct tgccgagtca
    48481 ctacttgggt atcgaattgc tcaaaaaaag caggatgcga ttgaattacc tgaattggca
    48541 attcaatcgg tgaatttgcg tacagcagca aatcaaaatc actggtttct tttactgccg
    48601 gaatcccagt cgataattca aatcctaagc tgccgccgat tccccattta catcctgata
    48661 atatgtttct agcagcatga aattgctgat aaacaggata atccatgatt ttctcttgtc
    48721 tatacgattc ttgttcgatg atgtcccacg gatgaatgac ttgtttgacg gcatgttttg
    48781 agatttctgt tgaccatctc tgattgcggg caggtccacg taaaccaatc ggtagtattt
    48841 ctgcgtgatc cgtcgacgca cgacgaactg ttccgaacat cttttcagtt agaacgaccc
    48901 attcaggcaa ggtgaaccct tctatttcat gtttatcaaa aaggacaata tcatgtgctt
    48961 gaatcatttt ttatgcatcc cattcttcgt ccattttggc acggacttta tttgtttcga
    49021 cacgtccgaa tgttttggct gtttcgtttg tgtatcgatt tgtcagcatc gtgtcatttg
    49081 tattgcggac atcttgaatg gcttcattga ttgcttcgat gactttgctg acattttgtt
    49141 ctgaagcagc ttggtcggtg atatcttcta ggaaatgata gatcgctcct agttttgtat
    49201 aattattgat atcgtaagcg atagctggaa ctttttcagc agctgcttcg atttcagcaa
    49261 ccgaacgttt tgtcacacgt gcagcacttt ctttagacat cgcttggacg gtaatttctt
    49321 tattgtttaa agcaatcaag cggcttgatt gtaatccatg tgctaaaaat gcacctgaaa
    49381 tagcatttcc tgcaatcaat ccaataactg gatgtccagc ttgacggagt tttgcataag
    49441 cagcagcact attagccaaa gccacatgga taccgatcaa ttcttcgtta tagccgtatg
    49501 cttggcttgg tacatcgatc acaacgatga ttggccgttt cacttttttg tctttatctt
    49561 cttcgtaaac gtgatccaaa atttgtccca tgcggaaacc ttcaactaaa ccaacttcac
    49621 cgtttcgtac acggtacatc gggtttttag gatcaggtac gattgatgtc acgatggctt
    49681 cttctatgaa tttacttgat ttaccataat acacagtact aatagaagaa gttggatttt
    49741 tcatgccagt tagtgccgca aaccaatcgt aaccaacact tgctgcagct ggttcatttc
    49801 cttctgctac ttctggtaag tcaattgatt ttgcttgatg gttagcaatt gcttcattgt
    49861 aatcgtcaat ggccattggt tttgaaagat ctaaagaatc aagtaatgat aaataaaatg
    49921 ctgagctttc actgcgatgc gtgtcttttc gttcgtccat tgctgcgatg acagcagctt
    49981 tgattgcttc tacactatca gtcactaatt catcaatgat ttttgattct acccgttgac
    50041 gagatcctaa tgtattccaa atcaagtctt tgtcactaga atcaaattct cgaacgcctg
    50101 cttcttgttc aataacttct ggtccattca aaccgactct cgcttttttt gttgcgatta
    50161 aataactcat taatgctgaa gtaatcgaca taccgccaaa tgatcctaca cgtcctggaa
    50221 tcaaaccgat gactggtaca tattgtttta gagcaatgat tacatttccg atttctgaaa
    50281 tagataacag tccgtagttt gcttcttgca aacgaacacc acctgtatct agtacaatga
    50341 ctggaaagat ctcatttcct tttttatttt cttctaacac atgttcaagt gcagcaacga
    50401 tttttgcacc ggaaacttca ccgataccgc caccttggaa ttttccttcc atagcgatta
    50461 ctactgcttg tttgccattg atcgtgccac ggctgacaac gatcccgtca tcactttcag
    50521 ggacgattcc ttgtgctggt aaacttggcg cgatgatttg atcgaatgga tcaatcaatt
    50581 cacgtccatt gtcaagtaga gcgttcactc gttctctggc gtttaattct acaaaactat
    50641 ttttcatctg aaagttcctc cattgcttgc gtcaatcgta ggtacacaac tcctggtgta
    50701 gcaccgaagt cattgatcac gatatctgct gaaattggat aacgatcaaa aaatctcgtt
    50761 aatacattgt tccatacttc gccgaagcca tcgcttcctg tacaaatttt tacagtagat
    50821 tctgtttttt ctgttggaaa catcaagatt tccaaatctc ctgaaccgac cactcctaca
    50881 tggattttct tattgatcgg ctgtttcgtt ggatatttat aagctaattg ttccatggat
    50941 ctctcccctt tttgtaaaac agagcataca cgttctgctt attcgtcttt cttcttccat
    51001 ctgggtaaat ggcgacaaaa ggtttttctc gccaatttta tgaccaagtt ctgaatttca
    51061 ttggtggttc atacaggcca tctgaccatt cgatcaaatc atcgatggtt tgtgcagcta
    51121 ataatgaacg tttcgcttca ctacgtttga tgcctagatc ttctggtaat ttcacgatgc
    51181 cggctgcacg caagctatct agtgattctt tcgtgctagt cattccaaga ggtgtaacac
    51241 cgccaattgc tgcaattgct gcttgtcgtt cttcttttgt ttttgctttg tacaaataag
    51301 caattccttc ttctgtcacg atatgtgtag tatcttcgct ataaatcatc actggtgcat
    51361 tggctaagcc tgcttgtttt tgaacagcta gtgcatctaa ttcttcgaca aagactggtt
    51421 ttttatttga accatatgtt tcaaccattt gaacaactaa tttttggcct ttccctaatg
    51481 gatcatcatt gtcgcgaagt gattgccatg ctggtgtaga atgacgacga ccgccaggat
    51541 tatgtcccat gttaggcgca ccgccaaaac cagataaacg tccttttgtt acggtagaag
    51601 agtttccttc gtaatctaat tgcaaggttg aaccgataaa catatcgatg gcatattgtc
    51661 ctgcagcttg tgataatgtt cggttactgc gcatcgtgcc gtctttaccg acaaaaaaga
    51721 catctgggcg agcagcaata tatttttcca taccaacttc gccaccaaaa ctatggatgc
    51781 tttcaaccca acctgattcg atggctggaa tcatcgttgg atgtgggttc aatacccagt
    51841 tcttcgcgat tttccctttt aaccctagtg attcaccata agttggcagt aacaattcga
    51901 tagctgctgt attgaatcca ataccgtgat tcaaagattg tacgccgtgt tctgcgtaga
    51961 ttcctttgat tgccatcatt gccattagaa tttgcaattc tgtgatgttt tgaggatctc
    52021 gtgtgaataa agcttctaat tgataaggtt tatctgcttt cacgacaacg tctacccagt
    52081 caccagggat atctacacgt ggtaaagaat cgacaacttc gttaacttga acgatcacga
    52141 taccatcttt gaaagctgca gcttcgatga ttgttggtgt ttcttccgta ttgaaacctg
    52201 tgtacaagtt gccgtcttta tctgctttat ctgcagctac taaaacaaca tttggaatca
    52261 aatcgatgaa taagcgtcca taaagttcca aataagtatg gatatcacct aatttcattg
    52321 tgccgtcttc aatcatttgg gcgacacgca agctttgtgc accagcataa gagaaatcga
    52381 tcttgcttgc gattcctttt tcaaaaatat tcaaatgttc tggtcgtgag atactagaca
    52441 tgatcaaatg cagatcattc actttttctg catctacttt ttcaagactt tctgaaagaa
    52501 aacttgcttg tttttgattg tcgccttcta atacaacttt gtcgccggga gcaatcagtt
    52561 tttccattac ttctacgatt ttttcagttt ctacatactt gccattgagc aagttgctga
    52621 ttttttccaa tcgctgcgct tttttttcgc gtttagaagc ccagttgcgg tttggttttt
    52681 ccataattag tcatctccat ttttgatata gaaacgtggc gtcatcaata ccatgttggt
    52741 ctagattgat cgtacggatc cctttatcta caccaaattt tgtatgaatc agctttgtca
    52801 aagtattgcc ggggggaaat tcaatcgtca gatccattcc taattctttt gccaagtcca
    52861 tcatttggtt ccactgcaca gggaaagcta ggttttccaa caaatcttta cgaatctctt
    52921 ctgcgtcctg agtggctctt ccatccgtat tttttatata caaacatcta gcatcagata
    52981 gatggacaga ctgcatatac ggcttgaatt tcttgaccgt atcattcatc aagagacagt
    53041 gagatggcac agggactttc agcagcttcg ctgtttgcgc ttggtgccgt ttggcttctg
    53101 ccaacgtaac ggataaacct tcgatactcc cagataacgt atgttgcatc ggacaatttt
    53161 catttgacag ataaactgga tggtcaggat caaatgtttt tgctacaatt tcctcagctt
    53221 cgcttctcgt cacacctact actacgccca ttgcataacc gcttggataa gcttctttca
    53281 ttaagactgc gcggtgatag actagttccg ctgcattctc aaatctcaaa gatcgacaag
    53341 caacagctgc acaaaaagca ccaatcgaat gtcctgctgc aatatcaggc tgaataccgt
    53401 ttttttccat ttcatctaaa taaaatactg cttttgtcag taatgctagc tggataaaaa
    53461 ccgtatcttg atagttttct tctttatcaa ctaaccgata ccccgtcaca ttttctaaac
    53521 gttccatgta catttcaggg atatccgcta acatccctaa cttctgactg ccttgtccag
    53581 gaaataagaa acctgtactc atgagcctcg cctcctcagc acttactttt tccactgcta
    53641 tcttagtcaa tttctgctat aataaaaaat gccaaaaaaa gaaaaaacca taacaaaaag
    53701 gtatggatgg gatggataat tatgaaattg cttcatctgc agtattttaa aaaagtattc
    53761 gaaacaaaaa atgttaccca agcagccaaa gaattattta tttctcaacc tgccttgagc
    53821 cgtgcgatca aacatttgga aaacgaatta ggtgtccctt tgttttacca tagcggcaga
    53881 aacattgaga cgaccgttta tgcagaagaa ttttatccat atgcagtcaa gacattagac
    53941 acattagaag aaggaatcaa attattgtct tcggtcaatg agaagatcgt tacttccgtc
    54001 atattgtatt tagaggtagc ctctgtttct attccgaact tggtccgaat ttttatggaa
    54061 aagcatcctg atatccaatt aacgatcatg caacatcatt taccagatga tattaccgat
    54121 cctgtactgt acatcacttc ggagatgaag cctggcatga ccaatattcc tatcatgaaa
    54181 gaacctgttt atgtcgccat tcctaagaaa catcctcttg ctaaaaaaga acatctgcaa
    54241 ttagaagata tccaacgcac ccccatcttg atgctgtcaa agagcaacgc cttccgtcat
    54301 acactggatg cagcacttga agcgaaaagt atcgaattga cgatcagttc gacgacagat
    54361 gatcctgcga cattacgttc tattgtcaag caaggattag ctgttagctt tttcccaaaa
    54421 gtttcttggt cttacgataa aaatgatcct ttcgtcttgc gggaaatcaa agatttgccc
    54481 ttgacacgaa caatttattt atcttctagc ttcacagaag atcatccttt gatcaaaatg
    54541 attgcaaaaa cgatgcggga attttattta ggaaaataaa aaaaaaagag ctgggacaaa
    54601 attcttgtcg cagctctttt ttcgaacaaa cggtgttcca gaagtaattt cttagaaaat
    54661 aagccgaaat ttcccaaaaa tttgagaagc aattttcgta aattccttct tatttcttga
    54721 agctaaacat ttctgtcaca acctcttctc tattgtccta gacattcatt gcgttgattt
    54781 aaaacttcca tcaatcaaat ctgctagttc atctagcttt tctattttac gtagatcaat
    54841 agagatccaa tgttctttat tcatgtgata ggctggaaaa tacccctctt ttcctcgcaa
    54901 aattccgcca agttcaggat cgaccttcaa atcaagaata ttgatgatcc tatggtcact
    54961 tgcatcatca tagatttttt cttctggaac agacatcagg accccaaacc attttttgct
    55021 tttttgatgt ctgaatacgc aataatcagg aaatttttta aaaatatatt ctggagacaa
    55081 attgtatgtt tcattgatgt gatcgattag ttcttttttc gttagcatct gcttccatct
    55141 ctttcttatt gattcgcttt attcaaagat accacgtaag aatagaaaaa tgaatacaag
    55201 tagttgctaa tcaaatactt cgatattttt cttttttatc aactcttaaa tgttcaatcc
    55261 gcctgtgttg gtcttgctac catctactat taaaatgttt attattgttt gcccacctat
    55321 tttttgattt tagtggtatc atttttcaag ttcatgatga aattcttatc atcagtaaat
    55381 gctccagaaa aataaacaat gattgaaaaa tcagttgaaa cttgaccacc gtttattttc
    55441 tccgtattct tagaatagaa gggagtctga ttgatgtatt cactaatgaa aaaaatcatt
    55501 accgaaaaag atattcgacg tcatgtttct ttagtagaac aattgctgaa tcatacaaag
    55561 ataaccgtaa atgaattagc tgaaatcata gggacaaccg aacgaacgat tttttctgac
    55621 cttcaatcta ttcgctctca gctgcccgaa ggctgggaca tcatcagcga tcaagcagga
    55681 atcagtttgc aaaaccagca aaatttatta acaaatgacc tttgggagat ttttttcaaa
    55741 caatcagtca gtgtcgaact gctgaaaaat ctgcttttta caaaaaaagt tgctgtccct
    55801 gattttctag ccgaccatgg gctttcttat gggacattga aaagacatgt gactaaaatc
    55861 aatcagcgtt tagcaagtta cgacttgcag atcgatttga cgaaatatac agcttgtatt
    55921 cttggaaaag agcgtgcgat tcgtactttt tatcatcgat tgctgattcc tttcactcat
    55981 aacaactatt ttttcgagga ttattcgatc catgaatccc attattttca atttttaaga
    56041 aacctcagtc aaactgaact agcggttgaa acagaagaga ttttcggaac atgttggttc
    56101 tttatcaata cgatccgtat aaaagcgaat tgccgattag attcttctat ccataccaac
    56161 agcacactct cctccctgta tgactctgca ttgaaaaaat tgtatttaac ggaaggtatt
    56221 tatcttaaag acactgagct ttcttttgct tctttctgct ttctggaaag ttggaattac
    56281 aacaataact atggacaaga aaccgctcgc tgcctgcatc attctccatt tttagaggtc
    56341 ctcgaaacgt ttgtagagga actagcttca gagctgtctc ttgatcaact aaaaaaaaca
    56401 tctctgactg ataacttggc tctcctcata ttaaaatatc atgaatcgcc gatattgatt
    56461 gaagcattgg accgtcaata ccatcgtttt ttagaaacat atgatcagca atatgcacac
    56521 ttgtatcaac agaaagagaa tttactgaac gatctaaaaa aagaaataga aatcaatgaa
    56581 ccaaattact ttctccaact cttgtctcta ctgatccaac aaacgatttt ttctatcaaa
    56641 ccgaatttgt tcaatgtcta ttttattttc caaggagaac cttcatggaa ggcgttcttg
    56701 cagcaggaat taaaagatta cttaggaaaa cgtgtctgct tcttacctat cgaactaacc
    56761 gatctttcca ctatttcttt tgaaaaaaca gatatcttga tttccaattt ccctctagat
    56821 tctctagata tccctattgt atacatttct tctattccaa cgaaaaatga gctcaatcgt
    56881 ttgactgaac tcactttcaa aactttttta tagtaacggc tagcgactgt attctctagc
    56941 tgttttttct tttttgcgaa acagtttgtt catgatccct ttttctattt ctacaactaa
    57001 gaatagaaga atcacatttg ctccaatcaa taactgttgt gtcatcgtta aacttactgt
    57061 accgatcagc tgctggccga ctggtagaaa aataaccatc ccttgcaata aagcaaggat
    57121 acctaatgaa agaaaaagcg ctttgttttg caaaagacct tggttcaatg acggcttgga
    57181 caactctctg caattgatca tgtaaacagc ttgagctaag acgatatttt gcagaagaat
    57241 ggtttgctgt aagctttgcc cttcaaactg catagccaat aaataggcag gaaccatgat
    57301 cagtagggag acatagatga tccgaaacaa atgataacca gataggattc cttgctttgg
    57361 atctcttggt gggcgcttca tgatttctgg atctggcgac tcgaacccta gtgcataaga
    57421 taaagtgatt gtcgttacca tattgaccca taaaatctgt actggggaca aaggtagcgg
    57481 gcgattcagc ataagtgccc aaatcaagat caatccttga gctaatgcag ttggcaagaa
    57541 gaaattgatg gttttttgca aattatccaa aatccgccgg ccctctttta cggcttttgc
    57601 aatcgtatgg aaattatcat ctcctaaaac catatcagct gcctgtttgc ttacttcact
    57661 acctttgatt cccatagcaa ttcctacatc ggatcttttc aaagcaggtg catcatttac
    57721 gccgtctccg gtcattccga cgatttctcc atttttctgc aaagctttaa caattcgcag
    57781 tttatgttct ggtgtcgttc gagcaaagac atcgactatt ggcacttgct gaatcaactc
    57841 ttcatcagac ataagatcca aatcgatccc ttctaaaact ttggcagtat gttttaagcc
    57901 aatttgttcc gcaatcgctt ttgctgtgtc tttgtgatcc cctgtaatca ttttcactga
    57961 gatccctgct tgttggcatt cctttacagc tttgactgca ctttcttttg gcggatcgat
    58021 caatccggcg atccctgcaa aagttaattg ggttaaagtc tcatgcgtga gttcctgttt
    58081 cgaatctact tttttataag caaatcctaa aacacgctga ccttttctcg caaattctgc
    58141 agctgtctga ctccatgctt cttgttctgc agaagaaaga gttgatttag caaataatac
    58201 ttctggtgca cctttgacgt aaatcaccgc tcctttttcc tccgcatgca tcgttgccat
    58261 atatttgtat tcagaactga acggaatctt tgcttctatt tttttcaaag gtagattggc
    58321 tgtttctgtg tgtcgaatca gcgcaacttc tgtcggattg ccacttaaat tttctgtttt
    58381 ctgttcttct tttgttttta attcctgaca gtttttcata atggacaaca cgcaggcttc
    58441 ttcttttgca gctacatcca caactgtcat ttcatttttt gtcaatgttc ctgtcttatc
    58501 tgaacagatc actgtcatag aacctaatgt ttctaccgaa ggaagtcctt tgatgatcgc
    58561 cttttctttt gccatttcat gtactccaac ggatagaatc atggtcaaaa cagctggcaa
    58621 tccttcgggt accattgaca ccaccaaagc aatcgtagcc gaaagaagaa tatgccaatc
    58681 cataccatat cgaaatgtcg taaaaataac taagaatagg ctcaaacaaa gaatgccttg
    58741 aaaaatttgt ttgtttaatc ggttgatttt tttaatcaga ggcgtcgttt gttgttcgac
    58801 cgattgcaat gcttgattga ttttaccgat ttctgtcgtg tttcctgttt ctacaacgac
    58861 accgactgca gaaccagatt gtacaagcgt tcctgaaaaa cccatatttt tctggtcgcc
    58921 gatcgattct tcttctgtca aaacggcatg acttttttca gatgcttctg attctcccgt
    58981 caaaatcgat tcttccacta ataaatcatg tgcttcgatt aatcggatat ctgctggaac
    59041 gacatctccg gcacgtaaga caatgacatc tccttttacc agttctttcg cagggatttt
    59101 ttcttgcatc ccgtttgata gtactatcgc ttcttgtccc atcagctgct tcaaaccatt
    59161 caatgattct tccgcttttc tttcttgcca gtaactaacg agtccattga cgatcactac
    59221 gaataaaata atacttcctt caatatattc actagaagca aatttcaaaa aagaggcaat
    59281 gatcaacacg atcatcagca gatcagtaaa atgctttgct atttttttcc atcgttttgt
    59341 ctgctgcctt gcttttattt cattatatcc ttgatcagtc aggcgtttct gtcgttcttc
    59401 ttgcgacaag ccttctgttg atgtttgata gtttttcaat acatcttcta ccgtcaatct
    59461 gtaccagttc atcctatccc ctcctgttta attgatactg ttattatacg cagggaagtt
    59521 ttttcaggcg tatcgattat ttcagggggg tctgaaataa ttcgttttgc aaaatgtatc
    59581 tgggcctaac tgatatttct attgcttatt cttttatata caaaatttaa gaatacaaac
    59641 cagataacca ataaaaaagg aataaagcgt gtcgtgcttt cgaataacaa gctgaaagca
    59701 attgaagtaa aaaacaccaa caaagcaaga tctttatatc tttgtgtagt gttccgtttc
    59761 ttttctttaa taaattgaac atgtgcacac aagatcgaag accacacaaa tagaaaacaa
    59821 ctcgttgtca tgcctgccaa aagctgaaaa aacaatcgac tatcagctac aaaaaaatgt
    59881 agacaaagac cggcaaaaaa taacattcct gtaattaaaa taccgtgtaa aggtacgcct
    59941 ttcttagaaa gcgcacaaaa ccaatggggc aaactttttt cttttgctgt ttgatataaa
    60001 atcctgctag tactgtagac tgcactattt gctgaggaca aagaagcaac caaaatcatt
    60061 agattgacaa ttgctgctcc gccttggcaa tggatcactt gcagcatagt cactaaagga
    60121 ctttctttta aatctaaaca atgccatgga acaacaaata aaatcgacaa aatcgttcct
    60181 atatagaaaa agagaatacg ccaaggcaga cagttgattg cttttttcaa attcttttgc
    60241 ggatcacttg tctcgccaac ggttaagccg atcatttcaa ttccagcaaa actgaataaa
    60301 accataggaa atgagactac cattccagca aagccaaacg gtagtaattc atcgatctgt
    60361 ccaaaatttt ctttgattcc gatagactgg gtatgaaaat ctgagacact caatcctata
    60421 cccaataaga taaaaaggaa aatccccaag atcttgatga ttgagaaaaa agattccaat
    60481 tcaccaaacc acttgactgc aacaaggttg actgccatta agatcattag tgcgctacct
    60541 ccgcttatca aagctggtac atgtacaaac cagaaatgga tatacaatcc tattgctgtt
    60601 aattccgcaa gtccagctcc aagccagcaa agccaataag tccaattgac aaaaaatgcc
    60661 cactttttgc ctaaataata gtcaacgaaa tcactgatag agttaaatgt actatttgct
    60721 aaaaataaat cacccatggc ccgcatcaaa ccataaatag ccaaaccgca tatcaaataa
    60781 acgagaataa cagctggccc tgctgatgca attgcctttg ctgaacctaa aaataatcct
    60841 gttccaattg cgccacctaa tgcgattaac tggatatttc gattagttag agtccgtttc
    60901 attgccggtt tttccatcaa gttcaccttt ttctttttca agcagcatgg cgacttcctg
    60961 ttcccaagaa ggtttcttta ttttttcaat acagagtggt actacaaaca aaatgacact
    61021 gatggctgtg actgcaatta gattgatcca tgttccagct ttcatcgtca gtccgacaga
    61081 aaatccgatt gccgcaaata aaacaataac gacagtccaa actccaagat tgctcttttt
    61141 ctcttttttt ccaattctaa atggtcgatt caactttgca tgtgtataac gcaatctcaa
    61201 aactgcgatc cccatgatga catagacgat acagtagata acagtagttg aatttacgag
    61261 catcaaaaat gcttgattga cgccaggaat cagcaaataa aaaagtgcaa agattgagat
    61321 aatgacagac tgagtcaaaa taacggattt ggatacgtca aattgattcg tcttccaaaa
    61381 attgaatttt ggtggatacg caccttttct agcactttct gtcactgtct ttgctggtcc
    61441 tgaggcccaa gcagataatt ggactgctac accaatgaag acaagtaaac taaacagatt
    61501 cacaataaga tgtggcaaac caagaatttg gcaataaatc gaaatagatt gcgcgatatt
    61561 attcaattcc atttgtcctt ttggtacgac atttgctaca actaaagcat tcaaaatatt
    61621 gacgaaaaat ataaaaatta acgcggcaaa tactccgcga atatacgttt taactggatt
    61681 ttccaatcga gtgatataca cagaggacat ttcgatacca gtaaaaataa acatgatcgg
    61741 cgcaaaataa acaaatgagg atgcagtcgt agtatctggt attaatttgt cccatgaaaa
    61801 actgcctaat gttccggttg gtacgatccc aactttgatc cacgcagcaa accctaataa
    61861 gagcatcatc gtcaaaggca cgtacaatcc taaccaaaca ccgacttttc cgccgatttt
    61921 tgccatatca aatttcaaat tcaaaaaagt gatgatccaa taaacgacta aaatgacaac
    61981 taatgtaaat ttgctgttca aaccaagcgg cacattatcg ataatattac caaacaacgg
    62041 agcgagtgct gaagcgacca tcaccatccc aggaaacatt tggacccata acagccatga
    62101 gacaacgaac ccccattttt ttcctagagc attcgatacc caaagttctg gaccaccttt
    62161 ttggggaaac attccagcaa attcaccaga gatcaatgag attggaaaag cgtacaataa
    62221 tactgcaacc agcatgtaaa aaatcatcgt ccagctcgtt gctgctacat ctggaatatt
    62281 tcgtacactt gctacaaggg cgcaggtcat tccgataaag gtcatggtcg tgatttgctt
    62341 tgatgaacca gtatctttca tctttattcc ttctttcaat agcgacatat gtttttgttt
    62401 tcttttattt ttgttcaaga acagaaatga caaggtttca tcgattcagt acaaaaccca
    62461 gtatcaccga aacatccatt gaacgatctt agtgaactgg gtttgataca tgaaacgaac
    62521 gatccaactt atagaacgtt ttataaaaaa gaatatcttg gcgaggaata tatgaaaaac
    62581 agggggaaat acaattgttt tgatgaagca aataattgtc tgttctccat atgtctcttg
    62641 ttattctttc acacaaaaat cagttctatt ggatgatttc gtttagtttc ttttccattg
    62701 ctttggcgat tttttttgta taaaaattga aaattcgatc atcattcaaa taaggagtca
    62761 tgatagccgc acgtagcaga gtgattttct gttctttttt ccattcttct ttcgttagac
    62821 ccattctttc aacaaaacga atcggagaat caccgtaatc ttcttgtgta aatgtagtat
    62881 gagaagtaat aaaccgttca ccataaacat cgccatccat ataagaagac cgatcgaaca
    62941 ttttttcatt taattcattg atagcgttca aatctgtaca gccttgttct ttgaataccc
    63001 aattgaccat attaaaatca ggatgattca atggatagac ttcgattgtt tttcctttaa
    63061 cagtaaaagt cagatgatcg agaaattctc tgaatctttg agctgcctcg attgaagccc
    63121 caatcaattg accatatccg gtcacattca atggcaatac acgatgtgct gtccagactg
    63181 cggcggcggt tgctccagct tttgatcctt ccaaaatata agctcctaac atatctggag
    63241 cctttactga tttttcaaac acatatggcg cgaaataaga aatgatattt ctcatatttt
    63301 tatgtttgat tacgattcct ccagcagcat aagggacata gcccatctta tgaggatcta
    63361 tcgtgacaga atccgcttct gaaatagctc tgaacccttc atatacctct ttgtcaatcg
    63421 ttacgcagtg gtggaaaaca tgatgttctt caaagaattc agctaaggaa gcatacggca
    63481 caaattctcc tgcttcgttt agaaacagtg aacgcgcata gccgccatat gcggcatcaa
    63541 catgtaaata gaaatagatc ccttcatctt ttaacctttc tcttaattgg acgattttat
    63601 ctacactgtc tacttgacct tcttctgtcg ttcctacgac agcaaccaca cctagaattg
    63661 ggattttttg tccagctaat tcacgaattg ttttttccaa agcattaata tccattcgat
    63721 aatcctcttg aactgggata gcaaccatct gatctaagcc gactccgcaa atatctaacg
    63781 ccttcatcca agaatagtgt tttgtttgag ggaccagcca tttccctaat ctttggatat
    63841 tttttccgct acgggaagaa gctgctttga cctcatccat ttcttcgtcc gtaaagcttt
    63901 cggtcatttc caaaatttct tcaacagata aattcaaaag ttcccactca gacatttttt
    63961 tcactttttc aggcagcact tccttgacag ctaaaggaat cgatttgatg caacgggcgt
    64021 accataatcc ttcaagatta gcaatagaac catctgctgc aatgtgtccc catccgtctg
    64081 tcatattgaa taatgaagca aaatcctgtc ctacttctgc ttccatttgc gaagttgcca
    64141 tagaagattc caatgcaaca ttatttgggt tccacagcat cgcatagttg taagctaata
    64201 aagcaggcat caatgtttca gcattcattt gtccccagta acggcctgct gaatgccatg
    64261 ggatcgatcc tgcgcgtaat cgctgactga cttcatccaa gacctctatc atatggtcgc
    64321 gggtggctag ataatctgga gtgagcttat ctccttcgct aattgcaggc atatctgaag
    64381 gaatataatt ttctctccat ccaagatgtt catctaccat cttgttcaac aacattttat
    64441 aaactggtcc attttcagct ttgtcgccta taaagacggc cttgatatcc atatctttca
    64501 tttttcttcc ctccatattt tgttggtcaa tgtcttgcag atacatgtgt ttatctgtaa
    64561 cacctcttca ctatagcgcc aaaaatgaga attttttttt tataacatca aatccacgta
    64621 gatttttaca aacaaaaata aataaagtcg gatttttctg ataattcaac gcaaaaaagc
    64681 gaacaatttt tcaataaatc agtcttctaa aatagataac ctaaaaaaag cgaacaaaca
    64741 aataaaatga ctgtccttca ttcactaaac atatttttat ttttttatat tgttaaaaat
    64801 tcgcaattta ttttttaata gaattatctg ttttccaaat tttataacat aaaaaacctt
    64861 ttttaacggc atttatatgc tttttcagaa attaactgat gatttcaaaa agaaaacatg
    64921 tcataatatt tcccatattg tgcaaaaaaa tacaaggcgg aggctctact atgattgaag
    64981 aatatattga gaaaaatatt ttaagacagc tgtttttatg tgggcaattc tatgtaaata
    65041 aagaagtcaa tctagaaaag ctctccaatc tcctgcatgt ttgcaaaacc actttactca
    65101 atgatatcaa taacataaaa aaagaatttg aagaacagat cgcttataca catcgggaaa
    65161 aggaccgtta cactttatat ttttcagaac atatacctcg atgcaagatc atgcagcaat
    65221 tgtctcaaaa ttcgttgttt ttaaaaactt gtctgcttta tttggaagaa gatgaacctg
    65281 attatcttca attaactgaa tgtgaattca tctctgtcag caaagcttat tcattaaaaa
    65341 aacaagtatt agcttatttt aatgactgcg ggatcgaaat cgaccgctac tcccctcgat
    65401 tcactgaaat ggaaagacgt ctgctgcttc ttaatgtgtc gtatcgttta ggcggtttta
    65461 attcttggga gctacctgaa tcgttttttg aacgtgccga tcgtttcatt gaatccgtaa
    65521 cggaaaatag tggcagattt tatgataaag aaaataaaga aatcttatcg attggttttg
    65581 ctatcagttt cctacgccag caagtgtgtg ctgtgacaat agattcaaaa tttatcgaag
    65641 aaatcaaaaa acgtcctatt tacaattatg tcgaatcagc atgggaaaac actgatttcc
    65701 aaacctatta taaaaaagaa gaattcgcct ttattttgac actattcaat ctttgtaatt
    65761 atggtttcca ttcttatcag ttgattgcgg aagactttca acagctacac caagtgttta
    65821 ttgacaatac tcccgaaata aaagaactag ttgctacctt tgaatctcac ttcaatcaag
    65881 aattattcgg aaaccaaccg ttcgaacgtg cgctgattca tctgatgcgt tcggcttggg
    65941 ataactatca attattcatg ccagaaaaat tttatctttt aaatgaggaa cagacaaatt
    66001 tatataaaga agtccagaca attttttcca gctggtccag ccagttacct tatgatctac
    66061 ggttgaatcc taattgcatg cgggcttttg tgatcgaatt gagcggaatt ctccgtctga
    66121 caaaagaaca tctgactatc tatatcgtca caaattcgga tgttcattat ctgatttatc
    66181 gggaagcctt ggaagctgta actactttcg attttcaagt tgcaccaaca atttattcaa
    66241 gtatatctga tataaagaag tatgcgcagc agtcctcaaa ccgggtatta tgtgaacgta
    66301 cattatatac accagatgcg gtccaatatg aaaatattat tcctatttcg atcaatacga
    66361 tcgatcgagc tatcatttca gctgtgcaaa acaaataagg ggctgtgaca aaaatcatgt
    66421 cacagcctct tatttgttga agatgcccat ttctgtaaca atctcttgat acacgtcagg
    66481 ctcacaacct cacttatttt ggacatctac gggtccgatc tctttattta aaaaataaga
    66541 aatgatggtt cggataacta ccaacgccgc tagttggaaa atatcctgca aggtaggttt
    66601 gataatcgat tcgatgatcc cagctgaaac aagaatttcc aaacttagaa gtatatagcc
    66661 tcccaacatc tttttaatag cattgttctc gctgactcgg tcgctttgca cttttgtatg
    66721 gacaaataaa tatttcaaaa aatccttgat tgatagacaa acaccccaaa ccaataaaca
    66781 gatagcaaag atatcaagtc ccagtacaag tttttcgaaa tatggaagaa gaaactgcat
    66841 caactctgtc gtcatcctac ctctcctctt ctttgttttt ctttgtcttc tatttcctga
    66901 ttcaagaaat aagaaatgac tgttcgaatg ataataataa gtgcaagctt caaaatatct
    66961 gtccaagtcg gcttgataac tgactcgatg atatcagcaa cgactagtac ttccaagctt
    67021 aacaaaatat aacttgctag cagttttctt gtatctgcat tacgagtatt acgttctgca
    67081 tagtttttct tgacatgaga ccaatcaaaa agtttgaata gaacaagaac gatcccgaca
    67141 attaagatac cgatagaaca aatatttaaa atagcaatga tccattctag aaattcaatt
    67201 aaatttgagc gaaacatata cgctacctac tttcttttaa tttgttccta ttcttttatt
    67261 gtaaaagaaa gttaccttgt tcgtctattt aaaagttgtt ctaatgataa cggttcgctt
    67321 aaatttttct ttttcactct cccatttttc tccctccatc cataaatcgt ggaagtatcc
    67381 aaaacaacgt agcaagttaa aataaggctt agtccgtcat cagcttttca aagaagcact
    67441 gtctcggtgc tttttttgta cccaaatttc taaaaataga accatacacc tcctcaaatc
    67501 ttttcttctt acctacccta tttttattta caggaaaatc agacacttct tcttttttgt
    67561 caaaatttcc tttttcttct cgtcctatca tttggcattc taataaaaac gaactatcct
    67621 tggatataga aagagaaaac aaggaggcgt ttttcatgag taaaaaatta atcaaagtcg
    67681 gcatcggttt aggtttgctt gcccttggcg ctgcatatct aggaaaaaag acaggactat
    67741 tcgaagatga cagtcattta tatgatgaat tcgaatcaat ctagcatcct atttagttga
    67801 atcactacgg acatacttgg aagacattgg aggaatcaca atgagaaaaa gtaaagcaat
    67861 aatgattggt gccggtattg ccaatatggc agcggctgtt tatttgattc aagaaggcaa
    67921 atggaaaggg gatcagatca ccttttattc attggatgat cacggttcaa atgatggtgc
    67981 accgaccgac actgtagtgg atgaatattg gaataaaaac catccattag aaaaccaaaa
    68041 aggctatatt gctcgaggcg gtcgcatgct taattaccgt acctatgtag atttgatgga
    68101 tctgttaagt cgaatacctt ctgttactga gccagggatg actgctgaag aagatacgag
    68161 agattttgat gcaaaacacc gaacctttga caaagcacgt ttgatggaag gtggcaaagg
    68221 aatcattgat ggcggaaaac tgggattcaa taataaagac cgtattcttc tgactaaact
    68281 gattgctatg cctgattcag aagaagaaaa actagacaat atcactatcg aagaatattt
    68341 caaagatgat ccacactttt ttgaaacaaa cttctggttt atgtgggaaa caacatttgc
    68401 tttcagaaca cgtagttctg ctcaagaatt gcgtcgctat atgcatcaaa tgatttatga
    68461 attcactcaa atcgaacatc tagtgggcgt caatcgaaca cgttacaatc aatacgaaag
    68521 tattatgctt cctttgatcg agtacttgaa agaacaagga tgcaaaatca ttttgaaccg
    68581 ccgtgtcact gactgggaat tcaaagaaac accgatgcaa gatgaaatca ctgtgactgg
    68641 tttgaaaatt accaatacac tgactcaaga agaagaatac gttgtggtcg atgaagatac
    68701 agcagttatt ttcactaatg ggtccattac agattcagct actttaggag attacgaaac
    68761 accagctgta gaaaatatgg attatggtgc agcttctagt ctctggaaaa aagccagtga
    68821 acgtttctac aacttgggaa atcctgacaa attctttgct gatcgagatg caagcgaatg
    68881 ggtcagcttt accctgacga cgaaaaacca tttgttgttg aatgaaatca cccgtatcac
    68941 gactcaagaa ccaggaaatg ccttgaattc atttatttca accacaccga tcacgccgtt
    69001 aggccaaaaa gatgtcaata tgtctatcgt cgtgcatcat caaccgcatt ttacgtctca
    69061 gaaaccaaat gaaacagtta tttggggtta tttcctttat ccaagacgac gtggcgaatt
    69121 tgtggataaa cagtatatta aaatgaatgg aaaagaaatg ctagaagaac tgattggaca
    69181 actttcaaaa gtagatcctg gaccagtgaa tattcgtgaa aaagaaacag aaattttcga
    69241 cagcgtaata aataatatcc ctgtctatat gccttatgct tccgcgttgt tcaataatcg
    69301 tgccaaaagc gatcgaccaa aagtcattcc taaacattcg accaatctgg cctttacagg
    69361 agaatttgtc gagcagcctt atcagatgat ctttactgaa caaagtgctg tacgttctgg
    69421 agaaatcgct gctttccatt ttgcgggtat tcctatgtcc cgtcttgtca aaacaccgcg
    69481 ttacgacaaa gatattccta ctctagctcg tgccgcaaaa aaaatgtttg aataatcaag
    69541 aggttgtgaa aaagctgccc tgcatcaagt aataagaaca accaggctaa aacagcttct
    69601 tatgtttttg atttggttgg acttattacc gcagatgcaa gcttttgaac accgtttacc
    69661 aagaggttgt gaaaaagctg ccctgcatca agtaataaga acacccaagc taaaactgct
    69721 tcttatgttt ttgacttggt tggacttatt accgcagatg caagcttttg aacaccattt
    69781 accaagaggt tatgaaaaag ctgccctgca tcaagtaata agagcagcca agctaaaaca
    69841 gcttcttatg tttttgactt ggttagactt attaccgcag atgcaagctt ttgaacaccg
    69901 tttaccaaga ggttatgaaa aaggcgttta gtttcgagta tgaagaaaaa ttttgtgaaa
    69961 atggttcctc acgtttttgc ataaatttga cttaataccg agaaactgat cccttctgtc
    70021 ataacctctt tttatttatg tctgtttctt tttgaaaaca actatttttt caacgtttac
    70081 tctcttgcca atccaacatc atctaacgga tacaactatt tcaatgatta ccattacact
    70141 aaaaaatcgg aaacacacct ctccgaacac aaatacataa gactatagaa tgtttcattt
    70201 aagaaaaaaa gcgtttcatt atcaaaaagg taagatctcc tttaaaatga aattatctgt
    70261 agtactaata atgcagacaa ttttatgaat ctgaaaggag catctccaat gaaagcagtc
    70321 acttggcaag gaaaacagaa aatggaaatc agaaacgtag atgatccaaa aatattagaa
    70381 ccaacagatg caatcatccg tatcacagca acagccattt gcggctccga tctgcatctt
    70441 taccatcatg gtgaagcagt tttggaaaaa gggtatgttg taggacacga accaatggga
    70501 atcgttgaag aagtgggatc tcaagttcaa acattgaaaa aagggcaacg tgtggttatc
    70561 ccttttaata ttagttgtgg tcattgtcat ttctgcctga atcacatgga aagccaatgt
    70621 gatgaatcaa atccagatca gttatatggc gggcttttcg gatttggcaa gttgaacggt
    70681 aatcattggg gtggtcaagc ggaatatcta agagttcctt atgcagactc tacttcattt
    70741 gttgtaccag ataatgatct tcctgatgaa aaagttttat ttctatcaga tattttgccc
    70801 acagcttatt ggagcgttga aaacgcagga gtaaaaaaag gcgatacagt tgtgattcta
    70861 ggttctggtc cagtcggtct attcgctcaa aaattcgctg ttatggctgg agcagagcgc
    70921 gtaatcgcag tagatccagt acagcaccgt ctagataaag cggctaatta caatggggtt
    70981 gaaacttatt tcttagaaga cacggcacaa gctggaacag aattgtatga actggctaaa
    71041 ggtggcgcag atgtcattat cgattgtgta ggaatggacg gattagagcc tgtcaaagaa
    71101 aaagcgaaaa atttagtaag cttacaaagc ggcacaatct ctccattaca gatggcatcg
    71161 caagctgtca aaaaatttgg aacagtccaa gtaactggtg tttatatgac tccagcttct
    71221 tcttacccgc tgcaagaatt ttttatgcgg gatatcgctg tcaagcatgg acaggcacca
    71281 attatccatc taatgccaaa aatttacgca atgattgcag aaggactatt cgatcctaca
    71341 caaatcatta ctcattcgct gccactatca gaagcagcac aagcatatga gatctttgac
    71401 aaaaaagaag ataaaaatat aaaagttgtt ttgaaacctt gaattcagta aaaaatacag
    71461 gtgattttct ttatgcccaa aatcaaacga aatacccatg agatcgaaat aggaaaagaa
    71521 gaagatatcg aaatacgagg acgtcgcttc cgcttctatt tccaaaatcg ttacacattg
    71581 atctcactgg ctgtcgattt attaaccggg attttctata tttttggaag ccttgcttcc
    71641 ttaactaaaa tccccgatcg atatggcacc tatttttatt tggctggtgc tattttcttg
    71701 acgattcgtc ctattctcag aatcgtaagg aacattttta tttacgacga aaaaaaagca
    71761 atgaagagaa caagcaaaaa aaaagaggca tgagaatttt tcaaatctca tgcctctttt
    71821 ttcaccctat cgtatcactt tgatacagac gagcggtcgt cccactttct tccttgacca
    71881 ttgtcaaaaa tgtccactcg tatcgttcat aaaacgtggt atgatctgta attaagtaaa
    71941 gtttttcgta cccaagttga tgcatttctt ttctgatttc cgctaatatc cgcttggcta
    72001 tcccctgctt acgcttttcc ggttcaacaa acagggcaca aagatttggt gtcagatcag
    72061 ggcggttatg gaagtcgttt tcaatgacgc ccgctcctcc gacgatggtt tctttttcat
    72121 ctaagaccac ataccattga ggaatacttt ccttattagc gattccagta cgaatacttt
    72181 cctcatacac aacagcagga actccccatt ttgatgaaaa ccaattcgcg ctttgtttta
    72241 ctaattctgg gtgttctctt aatttgatcc agttatatgt aaccaatgtt taaacctccg
    72301 actaaaataa aacgtttaca aaaattatac aagtctttat gaaaattagc aatgacaaca
    72361 atagtgatgt aaaaaaaaaa cggaaaacaa tcacttgttc tccgtttttt gattaatcaa
    72421 gcatctaaag cttcttttct tctttcttgg atcgtagcta ccttgacgaa cggtagatag
    72481 atcaaaatag aaagaaccaa attgacagcg gctagtacac cacctgcaat actttttgtt
    72541 gccaatacac cgccaataat tggtggagtt acccatggag gcataacggt agctgctggc
    72601 actaaacctg tagaagtcgc aaagtaagca acactaacta agaccattgg tgtcaaaata
    72661 aatggaatga acatgatcgg gttcaacacg ataggtaacc caaacatcgt tggttcatta
    72721 atattgaaga cacctggcgc aatcgacaag tttgttacaa ccatatatgg tttgttttta
    72781 cgtcctacta aataaatagc taacagtaaa cctaaagttg cacctgttcc tcctaagttg
    72841 acaaagctgt caaagaaagg tttgttcacg ataaacggtg cgctatgccc agctgcgatt
    72901 gcattaacgt ttgcttcaat ggctggcgca ttgattgttt gcatcaaagg atcgaccata
    72961 ttcgctccgt gtaaaccaaa gaaccataag aatggtgtga taaatgcaag cagtaaggca
    73021 gatggataag agtttgcaag tcccataaat ggttcttgga ccactgtata gaaagaacct
    73081 acgatatcat caacaccgaa tgcagcaaaa attgcagcaa ctaaagcaaa cgcagagata
    73141 gtgatcattg ctggtagtaa tgaagcaaat gcttttgcaa ctgccggtgg cacaccatca
    73201 ggcattttga tgatcaattt ttcatttccg cttaaacgta caaagatttc tgttgaaata
    73261 atcccaacaa taatagcaat aaacaaaccg tttgagctca tacctaatgc tccgcctaaa
    73321 gcgaagaaag agcctaaaga aatcacacct gcggaaacac cgtcttttcg gtagccgtta
    73381 gctaaatgat aagcaagcaa gaaagcaatc aagacagaaa gaatggcaaa tgtaccgttc
    73441 caagcagcag ccccgaatcc tttccatgat tcaccaccaa aaattgagtt catcaattct
    73501 tggaacccgg gaatcggtaa gttattgatc attactgcta atgctcctaa gatcattaac
    73561 ggcatactca ccataaatga gtcccgaatc gcaactaaat gccgttgtgc accaattttt
    73621 gatgctacag gtataaaatg tttctccata aatgcaacaa atttatccat aaatcttccc
    73681 tcttttcttt actgtagatt acgcgttcaa tcgacgatac agatcaatga tctcttttgc
    73741 taaatctgta aaagctatag atgtcatcag atgatcttga ctgtggaccg tcaaaagcgt
    73801 gacttcaacg tgatttcctt gtgcttcttg tgtcagcatc tctgtttgag agtgatgtgc
    73861 ttggactaaa gattcctctg catctttgat tttttcatct gctaaagtga aatcaccttt
    73921 tttcgcagca gcaatcgctt ccattgcatc gctttttgca tttccgccaa acatgatcag
    73981 acccatgatg gcttctagat ttttttgatc ttccatttat tgtatcctcc gataattttt
    74041 attatttgtt tattagtttt tctgcttggt cgagtacttt ttcaccattc atcatgccat
    74101 agtcagccat attgattaca tctaaaggaa tgcctttagg tgctagcttt tcagcaaatt
    74161 gattttgcat aaagcgtact tgcggtccta aaagtaaaac gtctacattt ttagattcta
    74221 gttgattatc cgcatctgaa gcagatacag caaagatgtc tgcttccatt ccttttgctt
    74281 ctgctgcctt ttgcattttt gtgactagga gacttgtact cattccagct gaacatacaa
    74341 gcatgattgt tttcttttcc attttaaaca cgttcctttc tatacttaca cttgtatata
    74401 agcaagtagc gtgccaactt taaaagcgct ttaaaaagtt gatatcatca catttaaggt
    74461 ctataccaag ttgcatacac actaaaaaag aaagcgcaca ctaaacacac aaattaattt
    74521 ttattacctt ttttctttta acgtgcacaa aaaaagttgt gacacaaaac ttgtcacaac
    74581 ttttttcaaa taaacggtat tcaaaagctt gcatctgcgg taataagtcc aaccaagtta
    74641 aaaacataag atgttgtttt tactttgcta ttcttattac ttgatgcagg acagcttttt
    74701 cacaacctct caataaacgg tgttcaatca gctgaccctg ggtattagct caaaacgctg
    74761 gattcacaac ctcttttatt tcaaataacc agtaaataca atgaacatct acaaaaaact
    74821 tctatttatt tatagatttc gtcaggcaaa tccaattctc tcttatcaat caaagtctga
    74881 taccacgaag cagatttttt caatgttctg cttcgttcat cgttcaattc gattcgaact
    74941 aatccatatc gattcttaaa tgcattcatt ggtgacacac agtcagtgaa tgcccataac
    75001 atatagcctt cgcaatttgc gccttcttct gttgctttga tcaagtaatg caaatgctgt
    75061 ccgataaatt cgatacggta atcatcttgc acgattcctt tctcatccat atactgttct
    75121 tcatattctc ttcccatacc gttttctgtt atcagccaag ggatattatg ataattttct
    75181 tttagataca tggctatatc atacatgatt ttcggataga tttcccatcc cctggaatta
    75241 ttcattttct tcccaggtaa atcaaagact tcataatatc gttcaggatg gaaaggtgtc
    75301 tcttcattcc attgataacg aggggcgcga acgcgtttag gataatattg attgattcca
    75361 aggaaatcta ctgtatgatg ctgaatcgtt tctaaatcct ctgttgcagg atcgaaataa
    75421 atcgattgtt tttgacacaa ctccaggaac tcttctgtgt agtatccttt taccatcgga
    75481 tcaaaaaata ctcgattata aaacaaatca tacatataag cagctttttg gtcttctgga
    75541 gaattggatc gagcatagac catttcagga tttaaaatac agccaatcct tccaccataa
    75601 tttccgctgc ggtaaatctc tactgcttta gccgttgcta aaactttatg ataattccac
    75661 atcatccact tttttgtgtt ttgttcatgc ggccagcgaa cagcatccaa atagcaacgc
    75721 gtttggggaa cgattggttc gttgaatgta aaccagtttt ttaccctatc accgtaacga
    75781 tcaaaggcaa tttgagcata cttagcataa aaatcaacta cttttcttga agaccagcca
    75841 tcatattttt ccaaaagaaa agctgggact tcataatgtt ccaaacaaat catcggttct
    75901 acgtctgctt cgatcaaaga gtcgatcatt tcacttatat gctgagcata ttcttcatct
    75961 actatacagt tctcataatc agtaaaaaaa cgagcccaat tgatagaagt ccgataatgt
    76021 gtcagatgga tggatttcat cagatccaca tcctgctggt attgttccat aaaattagtt
    76081 gctacggctg ggccataccc attatgccaa acaaaatgtt catttttata ccagctatct
    76141 ataaacgaat cctgtccttc tttttttcct ttccaacctt ccgtttgcca agcagaagat
    76201 gcagcaccaa gaataaaatt ttttggaata gtaattttca tgatttcctc ctgtttttta
    76261 gatcccatca ttttccacac gatttgctac ttttacaaat ggcagataga tcaaaataga
    76321 aacaataata caaacaagtt gcgtaataac tgcaccgata tttcctgctg ttgccagata
    76381 agcattgacg atcggcggca ttggccaagg gaccattaca actgctttcg ccgcaaatcc
    76441 taaagcggtt gcaaaataac caatcgttcc agtgataaga ggcgttaaga taaacggaat
    76501 agctaaaatt ggattcagca tgatcggcat accaaaaata actggttcat tgatgttgaa
    76561 gatcccagga gcaagggata acttggtgat ttgtttcata tcttcccgtt ttccaactaa
    76621 caatactgca atcagtaaac cgatcgtgac tccagacccg cccatactca tatacatatc
    76681 ccaaaatggc atagtaataa tgttcggtac ttcttttcca gcttcaaaag cttccgtatt
    76741 tacagcaatt gccgctaaaa gcaacggttc ccgtatcggc ttcaccattt gatttccatg
    76801 gataccaatc acccaaaaga cttgcgcaat aaacatcaat agcaaaatac ccggtaaccc
    76861 ttgtacgaca ccttctaatg ggcgttgtac gacattgtaa atgatatcat aaaggtacat
    76921 tcctgtaagt tctttgatga taaatcccgc agccgcgata cccgatacag tcagaatcgt
    76981 cgggaataaa gcagaaaaac tagcagaaac attcgttggc acggtatcag gcattctcag
    77041 ctgtagtttc ttctgtttcc tcaaccagca ataaagttca atagaaagga tggagaccaa
    77101 cattcccaaa aataaccctt tcgtatctgt atattgttta gccaatacgt tttctactat
    77161 aacagtctga ttttcattca ctaattcata aacagttgga ttaacagata aataagacat
    77221 cactgcgatg ataccaggga atacaccatc cactttattc agcttggcta attcgatccc
    77281 tatcagaaaa acagcataga tggtcaagaa acttagtgtg acatagctga tggcagatgc
    77341 gataggcttt aattcttcta aaaaacgcaa gaaacttatc tgtgctaagc cattttccga
    77401 gtcaaagacc attgctgaaa acaatgtgcc aaaagcaccc gtaataatta ccggaatcaa
    77461 tgcagcaaat gcgtttttta tcaccatgat ataccttaaa ttattgattc tcgttgccac
    77521 gttccctaaa acattggcta atttatccat aaaactcatt ccagatcccc tcattcctgc
    77581 ttcttctcct tgacgtcatc tctttttgtc tattagtcag cgcttacatt tcgatgaaca
    77641 gaaactattt actcctcttt tttaccaaat ataaaacaaa aattcatctg atgtatttat
    77701 cataaaatac atcagatgaa ctgtcaatta gtttcttttt ctcctattat tttctgtaat
    77761 tctctccgat ttattgccat atggacagtc attgcatcaa acgcagcaag tgcattccgc
    77821 ctttcgatgg cctgaacgat ctctgtatga atatcgatcg tctcgatttt cagatgctgg
    77881 atatcataat ttttattaaa caaagcaatt gattcattaa tgattgggat aatatgcagc
    77941 aaggctacgt ttccgctagc ttctgcaatc atcgtatgaa aatcgatgtc taattgaaca
    78001 tgttcttgtg tgccttctcg aaaagaagtt tcaatctttt gcgttaattt tttcatttgg
    78061 acgatttgat tcttcgttgc atattccgct gccaaacctg ccatcttagg ctccaataaa
    78121 tatctcagtt caaataagtc tcgtatcatc cgatcctgat cttcaatcaa agaaaaaccg
    78181 agtgggtcat tggcaatccc tcgcttatca ctgacaaatg tccccgctcc ttgccgaact
    78241 tcaaggatat tcctggaagc tagagcccgc acagcttctc gcaccgtgct tcgccccacc
    78301 tctaaataat cggacaattc atattcattc ggcagtttat ctcctacttg caactgcatt
    78361 tcctttaaat atctaaggat cttgtcagta gttacttcta ctagggtttt attttcttcc
    78421 aaaccacata cctccttttc atctgatgta ttttttcgta attattataa cacgtttgaa
    78481 tcatctgatg attttttgta tacaaaattg attaatccgt tcatagacat acaaacgaag
    78541 aagatattta ccataaaaaa gactagga
//
LOCUS       DADGKS010000005        68446 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.005, whole genome shotgun sequence.
ACCESSION   DADGKS010000005 DADGKS010000000
VERSION     DADGKS010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 68446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68446
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.005"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(43..1851)
                     /gene="uidA"
                     /locus_tag="JXV47_000323"
     CDS             complement(43..1851)
                     /gene="uidA"
                     /locus_tag="JXV47_000323"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003479936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HAX1486395.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(1874..3640)
                     /locus_tag="JXV47_000324"
     CDS             complement(1874..3640)
                     /locus_tag="JXV47_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HAX1486396.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(3653..4447)
                     /locus_tag="JXV47_000325"
     CDS             complement(3653..4447)
                     /locus_tag="JXV47_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAX1486397.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            complement(4457..5833)
                     /locus_tag="JXV47_000326"
     CDS             complement(4457..5833)
                     /locus_tag="JXV47_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAX1486398.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKASNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFLYPLSKDKVLENC
                     ELLKQKHK"
     gene            complement(5953..6600)
                     /gene="eda"
                     /locus_tag="JXV47_000327"
     CDS             complement(5953..6600)
                     /gene="eda"
                     /locus_tag="JXV47_000327"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HAX1486399.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(6684..8111)
                     /gene="uxaC"
                     /locus_tag="JXV47_000328"
     CDS             complement(6684..8111)
                     /gene="uxaC"
                     /locus_tag="JXV47_000328"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HAX1486400.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(8185..9264)
                     /gene="uxuA"
                     /locus_tag="JXV47_000329"
     CDS             complement(8185..9264)
                     /gene="uxuA"
                     /locus_tag="JXV47_000329"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAX1486401.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPACEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(9267..10898)
                     /locus_tag="JXV47_000330"
     CDS             complement(9267..10898)
                     /locus_tag="JXV47_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAX1486402.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            11202..11873
                     /locus_tag="JXV47_000331"
     CDS             11202..11873
                     /locus_tag="JXV47_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAX1486403.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
     gene            complement(12598..12933)
                     /locus_tag="JXV47_000332"
                     /pseudo
     CDS             complement(12598..12933)
                     /locus_tag="JXV47_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(13030..13482)
                     /locus_tag="JXV47_000333"
     CDS             complement(13030..13482)
                     /locus_tag="JXV47_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486404.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            complement(13489..14037)
                     /locus_tag="JXV47_000334"
     CDS             complement(13489..14037)
                     /locus_tag="JXV47_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAX1486405.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            complement(14082..14414)
                     /locus_tag="JXV47_000335"
     CDS             complement(14082..14414)
                     /locus_tag="JXV47_000335"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486406.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(14428..14658)
                     /locus_tag="JXV47_000336"
     CDS             complement(14428..14658)
                     /locus_tag="JXV47_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486407.1"
                     /translation="MCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQKGYPYGPTN
                     LKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(14880..15422)
                     /locus_tag="JXV47_000337"
     CDS             complement(14880..15422)
                     /locus_tag="JXV47_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486408.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VDQEAQKIDAIKIYYVRSAY"
     gene            complement(15443..16534)
                     /locus_tag="JXV47_000338"
     CDS             complement(15443..16534)
                     /locus_tag="JXV47_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAX1486409.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(16542..18752)
                     /locus_tag="JXV47_000339"
     CDS             complement(16542..18752)
                     /locus_tag="JXV47_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486410.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(18768..21296)
                     /locus_tag="JXV47_000340"
     CDS             complement(18768..21296)
                     /locus_tag="JXV47_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAX1486411.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            complement(21348..21758)
                     /locus_tag="JXV47_000341"
     CDS             complement(21348..21758)
                     /locus_tag="JXV47_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486412.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            complement(21771..21989)
                     /locus_tag="JXV47_000342"
     CDS             complement(21771..21989)
                     /locus_tag="JXV47_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486413.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            complement(21986..22978)
                     /locus_tag="JXV47_000343"
     CDS             complement(21986..22978)
                     /locus_tag="JXV47_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAX1486414.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            complement(23057..23968)
                     /locus_tag="JXV47_000344"
     CDS             complement(23057..23968)
                     /locus_tag="JXV47_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAX1486415.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            complement(23987..24331)
                     /locus_tag="JXV47_000345"
     CDS             complement(23987..24331)
                     /locus_tag="JXV47_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486416.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            complement(24351..24907)
                     /locus_tag="JXV47_000346"
                     /pseudo
     CDS             complement(24351..24907)
                     /locus_tag="JXV47_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(24988..25488)
                     /locus_tag="JXV47_000347"
     CDS             complement(24988..25488)
                     /locus_tag="JXV47_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486417.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            complement(25489..26034)
                     /locus_tag="JXV47_000348"
     CDS             complement(25489..26034)
                     /locus_tag="JXV47_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486418.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            complement(26031..27287)
                     /locus_tag="JXV47_000349"
     CDS             complement(26031..27287)
                     /locus_tag="JXV47_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAX1486419.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            complement(27648..27959)
                     /locus_tag="JXV47_000350"
     CDS             complement(27648..27959)
                     /locus_tag="JXV47_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486420.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            complement(27982..29292)
                     /locus_tag="JXV47_000351"
     CDS             complement(27982..29292)
                     /locus_tag="JXV47_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HAX1486421.1"
                     /translation="MYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLV
                     RMLIDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGH
                     LLSEVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPN
                     MLIAGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEE
                     MIICLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDME
                     ARNRVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYL
                     MTFGEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYD
                     FTVKEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            complement(29906..30358)
                     /locus_tag="JXV47_000352"
     CDS             complement(29906..30358)
                     /locus_tag="JXV47_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486422.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            complement(30360..30725)
                     /locus_tag="JXV47_000353"
     CDS             complement(30360..30725)
                     /locus_tag="JXV47_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486423.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            complement(30824..35107)
                     /locus_tag="JXV47_000354"
     CDS             complement(30824..35107)
                     /locus_tag="JXV47_000354"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HAX1486424.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            complement(35254..35493)
                     /locus_tag="JXV47_000355"
     CDS             complement(35254..35493)
                     /locus_tag="JXV47_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486425.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            complement(35583..35855)
                     /locus_tag="JXV47_000356"
     CDS             complement(35583..35855)
                     /locus_tag="JXV47_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486426.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            complement(35938..36189)
                     /locus_tag="JXV47_000357"
     CDS             complement(35938..36189)
                     /locus_tag="JXV47_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486427.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            complement(37185..38095)
                     /locus_tag="JXV47_000358"
                     /pseudo
     CDS             complement(37185..38095)
                     /locus_tag="JXV47_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171801.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(38291..40126)
                     /gene="lepA"
                     /locus_tag="JXV47_000359"
     CDS             complement(38291..40126)
                     /gene="lepA"
                     /locus_tag="JXV47_000359"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HAX1486428.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            40273..41493
                     /locus_tag="JXV47_000360"
     CDS             40273..41493
                     /locus_tag="JXV47_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1486429.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            41513..42007
                     /locus_tag="JXV47_000361"
     CDS             41513..42007
                     /locus_tag="JXV47_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HAX1486430.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            42000..42671
                     /locus_tag="JXV47_000362"
     CDS             42000..42671
                     /locus_tag="JXV47_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486431.1"
                     /translation="MIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGITFIVES
                     LLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWDKILHA
                     VSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLCDQFLG
                     MNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFESYKLE
                     KVKNT"
     gene            complement(42822..45431)
                     /gene="clpB"
                     /locus_tag="JXV47_000363"
     CDS             complement(42822..45431)
                     /gene="clpB"
                     /locus_tag="JXV47_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HAX1486432.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(45682..46728)
                     /locus_tag="JXV47_000364"
     CDS             complement(45682..46728)
                     /locus_tag="JXV47_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HAX1486433.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            complement(46739..47011)
                     /locus_tag="JXV47_000365"
     CDS             complement(46739..47011)
                     /locus_tag="JXV47_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HAX1486434.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            complement(47046..47954)
                     /locus_tag="JXV47_000366"
     CDS             complement(47046..47954)
                     /locus_tag="JXV47_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HAX1486435.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            complement(48086..49318)
                     /gene="pepT"
                     /locus_tag="JXV47_000367"
     CDS             complement(48086..49318)
                     /gene="pepT"
                     /locus_tag="JXV47_000367"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HAX1486436.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            complement(49333..50454)
                     /locus_tag="JXV47_000368"
     CDS             complement(49333..50454)
                     /locus_tag="JXV47_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HAX1486437.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            complement(50451..51152)
                     /locus_tag="JXV47_000369"
     CDS             complement(50451..51152)
                     /locus_tag="JXV47_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HAX1486438.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            complement(51296..51736)
                     /locus_tag="JXV47_000370"
     CDS             complement(51296..51736)
                     /locus_tag="JXV47_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAX1486439.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            complement(51865..52791)
                     /gene="dnaI"
                     /locus_tag="JXV47_000371"
     CDS             complement(51865..52791)
                     /gene="dnaI"
                     /locus_tag="JXV47_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HAX1486440.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            complement(52791..54164)
                     /locus_tag="JXV47_000372"
     CDS             complement(52791..54164)
                     /locus_tag="JXV47_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Replication initiation and membrane attachment"
                     /protein_id="HAX1486441.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            complement(54187..54678)
                     /gene="nrdR"
                     /locus_tag="JXV47_000373"
     CDS             complement(54187..54678)
                     /gene="nrdR"
                     /locus_tag="JXV47_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HAX1486442.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            complement(54990..55322)
                     /locus_tag="JXV47_000374"
     CDS             complement(54990..55322)
                     /locus_tag="JXV47_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAX1486443.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            complement(55374..56003)
                     /locus_tag="JXV47_000375"
     CDS             complement(55374..56003)
                     /locus_tag="JXV47_000375"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HAX1486444.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEILVGQIENWLFANRFL"
     gene            complement(55967..56803)
                     /gene="mutM"
                     /locus_tag="JXV47_000376"
     CDS             complement(55967..56803)
                     /gene="mutM"
                     /locus_tag="JXV47_000376"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HAX1486445.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            complement(56848..59493)
                     /gene="polA"
                     /locus_tag="JXV47_000377"
     CDS             complement(56848..59493)
                     /gene="polA"
                     /locus_tag="JXV47_000377"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HAX1486446.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            complement(59619..60302)
                     /locus_tag="JXV47_000378"
     CDS             complement(59619..60302)
                     /locus_tag="JXV47_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HAX1486447.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGIILAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            complement(60295..60780)
                     /locus_tag="JXV47_000379"
     CDS             complement(60295..60780)
                     /locus_tag="JXV47_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HAX1486448.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            complement(61087..62421)
                     /locus_tag="JXV47_000380"
     CDS             complement(61087..62421)
                     /locus_tag="JXV47_000380"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HAX1486449.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            complement(62552..63313)
                     /locus_tag="JXV47_000381"
     CDS             complement(62552..63313)
                     /locus_tag="JXV47_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAX1486450.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            complement(63329..63811)
                     /locus_tag="JXV47_000382"
     CDS             complement(63329..63811)
                     /locus_tag="JXV47_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HAX1486451.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            complement(63831..66011)
                     /locus_tag="JXV47_000383"
     CDS             complement(63831..66011)
                     /locus_tag="JXV47_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HAX1486452.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            complement(66155..66886)
                     /locus_tag="JXV47_000384"
     CDS             complement(66155..66886)
                     /locus_tag="JXV47_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HAX1486453.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            complement(66955..67896)
                     /locus_tag="JXV47_000385"
     CDS             complement(66955..67896)
                     /locus_tag="JXV47_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HAX1486454.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            complement(68076..68444)
                     /locus_tag="JXV47_000386"
     CDS             complement(68076..68444)
                     /locus_tag="JXV47_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAX1486455.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
BASE COUNT        19873 a        14483 c        10677 g        23413 t
ORIGIN      
        1 ggctaggcta atcgtttttt gaacattctt aaaaaatcca aattattttt tataactgaa
       61 attgggtatt gatgaccatc gtttctgtag atagtaagca atcattttag gttttctatc
      121 tctagtaaag attcctttct tatttccttg cactcttaaa atcccttgac ttgttgcaaa
      181 atctgcaaaa ttccacactt gttcaccaac aaaattttca catgtatcta ttacttcgtg
      241 atttgcttcg taataagcca cttgatactc ttctgtaaac attgttggta ctgtatcatg
      301 aaatccagct actgtatctg ctccatattc tgtaaacatt attggcgtat caggacatct
      361 ttccatccat ccatctagct cttttttcaa cagatatttt gcatgtgcca gatcccctcc
      421 cgaaacatac caaccataat aacgatttaa acataaaaca tcgacaatat ctcctacctt
      481 acaaacatct ggcgttgatt ttagataagt aacgattgtt acaggtcttt tctgcggatc
      541 aagttcttta gttaattcaa ctaaaggttc aaaatattct ttagcacctt cggaatccga
      601 atctggttca tttgcaatag accacattac aacacttggg tggttcttgt cgcgttctat
      661 caattccttg atcaccgttt tatgagaatt ttctgttcgt atctctttcc acgtattatg
      721 tttttccaca ttatcatcta ataaagtggc catgaaattt aaatgtaacc ctactgcagg
      781 tacttcatca ataactacaa taccttctcg atctgctaat cgcataattt cttctgagta
      841 aggataatgt gatgttctaa aagaattagc acctatccat ttcattaaat taaaatcttt
      901 aatatttaca gcctcattca aaccacgtcc attaacatac gaatcctcat gcttaccaaa
      961 tcctttaaaa taaaaaggtt tattattaat caaaaatttg ccattggtaa cctgaacact
     1021 gcgaatacca aattcttctg tataggtatc gatcacttta ttatcatcaa ttaaactaat
     1081 tttcatacta tataaataag cgtctagagg ttcccaaaaa attggattct taagctgaat
     1141 cattcctttc tttccttcag cttcagctac aagttgagcc tcttcgtcat atatcgctat
     1201 taagattttt ccggtccatt ctgtatcgat attgaattct acacttgcat ccaaatcagt
     1261 tattcttgta ttaatagtaa tatcacttat atagtctttc ggagttgtat ataacttaac
     1321 aggtctatga atacctgcat aattgaagaa atcaaaatta actaagtttt ccttttttat
     1381 atccccattt tcctgtactg tttccttcat aatccccaca ggtaaagtac tatcgtcaat
     1441 aatattgttt acagcaactg taattcgatt attcccgtct tttacaaacc gattaatttc
     1501 agactcaaat ggtgtaaacc cacctttgtg ttgagtaata aactttccat tcaaaaaaac
     1561 ttttgcttca tgtgttgcag atccaaaacg aagaactaat ctttcttcta ataatctttt
     1621 aggaagagtc acttcttttt cataccacac ccatccaaca tgatttctaa tgttctctgt
     1681 ttcaaataaa tcattataag aagagggaac tgaaatcgga taactctctt tttcatttat
     1741 tggttctaaa gcaagttctt cctgtaagtc atcatttgta tctaatttaa atctccagag
     1801 accgcttaag tcaattactt gcctcgtctc tgtcataatg ggatacaaca tataaaccac
     1861 tcctatctaa atattaaata aatgtatcct ttaaaccaca ataagcatct attggactta
     1921 ctcccttaaa ttcagaaaga cccattagtt tgtccaccaa tatttctaaa gtttcttgtt
     1981 ttccatcata agtattaata taagtcttta cttgaggtac atcagccaaa tgaaacggac
     2041 actgtacaga tacaaaaatt gttggaattt catgaatgta aaacggtata tccggagttc
     2101 ctttacttgc tggccagaca attcgttgaa ctgtgcctgg attaacatta gctatattaa
     2161 tgatcaagtc atatttttta gttaaatttt taattggtct cttagcagca tatattccag
     2221 ctatattttt aattttttct tcttgcgata atcctttcaa ttcttcttca ggtgaaatgt
     2281 atttttcaac ttcaaatcct tttgctgaca aaatctgttt caataaatca atggcttgag
     2341 gtctatttcc agcaactact tcaccaaacc caccttttac cccatgtaca tctactagta
     2401 aaatcctttt atatttttct ggtacaatag gccaaatatc ttgtttatct ttaactaatg
     2461 taattgcttg gtcagccacc tctttaaaaa ttgatttatt ttcaattaaa ccaatttttt
     2521 ccagagcttc ttgcttaggt aataaaattt gttcttttgc ttttttgtgt aatcccaatt
     2581 tagcttttaa ccctaaaatt ctttttaaag catctaataa ccgatcatca gtgataattc
     2641 ctttacgata gccttccatc atataattaa agtcttcatc tggatcatta aaaaatagaa
     2701 atagatcaca tccagctgca atagaagtgg gcaataattc tgatcgtttc attgccccag
     2761 tcattcctaa catatgacta gcatcagtaa ctactaatcc attaaatccg agttttcctc
     2821 taagtaagtc agtgattaat tcttttgata aagttgcagg aagtaaatct tcatctttca
     2881 gatcaggatt aaaatgtttt gaataagctg gcatatggat atgacctgcc ataattgaag
     2941 gtaatccagc ttctattaag cctgagtata cttttccaaa agaattatcc cattcttccg
     3001 tacctaaact attaatacta aaagatagat gctgatctcg ttcgtcaata ccgtcaccag
     3061 ggaaatgttt agctgcaggc aaaattccac tctcctgaat acctttcata taagctaaac
     3121 taagttctaa aactttatca gggttttgtc caaaagatcg actagaaatg ataggatttc
     3181 tccaatttct attaatatct acaataggag caaaactcca gttacatcca atagccgatg
     3241 cttcaatccc agaaactctc cctaattcat aagcatattt cgcatcattt gttgcaccaa
     3301 tttttacttc tacaccaact tcagtaccat ctgtacaagc tccgttacca cctgcttccg
     3361 tattagcagc aattaataga ggaattttac tttctgtttg taagatatag ttttgatcat
     3421 atacctcatc agcagttcct ggattatatc gtacagctcc aatatggtac tgattgacca
     3481 tattactcaa gtaattttta tcacgactag atcccatatt aacaaacaat tgacctattt
     3541 tttcttccaa agtcatagaa tcaatcgtct cttcaatcca agaaatagca tcttcatcta
     3601 aattatatgg tttttttcgt aaatctactt ttatagtcat tttctttctc ctctacttat
     3661 tagtaagatt tttccaaaaa gtatctatat atttttgttc aatatctaca taatctcccg
     3721 ataaacattt aaataaaaca tcagttctta agttttccca tgattctttt tctttattga
     3781 ccaaaatagg ataaaagaaa actttatttt tatttgcagc ttctagatca ccaggagaat
     3841 caccaatcat taatatctta tccaaatcac aaccattttc aattacactt cgaataatat
     3901 cttctttttt tcctttatct tgacaacaca gttcatcaac taatgataat aattcatgtc
     3961 tttcccattc ttcttgaaca gcttccttat tagctgagct tacaataatt atcttcccat
     4021 attttttcag agcttttata gtatctctag cacttaaaaa gggtttatct aatccttttg
     4081 cttgactaat ctgttgattg acttcttccg accattttaa agcttttaat aaatcctctg
     4141 actgagaata ttctatttcc ctcttcaaag atggattaga caattctttt gttagagata
     4201 cccagtgctt taatcgatta atcgatgtta catcattttt ttctaatgtt ttaactaaac
     4261 ctaaaaatct gtttattcca cgagtctctg aatataaatt aatattattc caatcctgta
     4321 ggaatttttc tctatgatga acatcaaaaa tctctgcagc aattggtccg aaaaagagat
     4381 tgtgtttata agtcatcgta tccataacac agccatctga atcaatacaa aatatccaat
     4441 tattcatatt tctctcctat ttatgttttt gttttaaaag ctcgcaattt tctaagactt
     4501 tatctttaga taatggataa aggaaaaata aaattaatcc tacaatcaga aaacaaattg
     4561 atggaattaa tgttgaagcg ttatataact tttctaaaac atctcccgtt tgtacatttg
     4621 ctaaagagtc atagcctata atagaaagag tccaacctcc gacgcctcca gctagagctt
     4681 gacctatttt tctagcaaaa gaatataccg catatacggt cccatcttct ctttgatcag
     4741 actttacttc ttgatcatca ataacatcag taatatttgc ccaaataaca gtattaaaca
     4801 cacccaaacc catatagcca accgaactaa gaattaagaa tacatacata ttactagctt
     4861 ttatcaaaaa taagatcaaa tatactattg ctgaaaagaa cattcctact gatgccagtt
     4921 ctttttttcc atatttttta cttaaaaaca aagttaaagg cgaaacaact attaaaacca
     4981 aaataggatt gataaaattc attaaaacta ttccctgtgc atcattatag taatcaggaa
     5041 atacataatt attcatactc ataattaata attgagcaag gagtaagaaa atagccgcac
     5101 caattataga aagtaatgcc ctatttttaa ctaacccttt taaagatttt aacaatgaaa
     5161 ctttgtattg agattggtca attcttactc gttcagtagt tagtttataa catattaaat
     5221 aacaaataag tgcacatatc gaaaatattc ccgcaacaat tgtaaaagtt gatccaccac
     5281 gaactatttg agcgcctgaa tcatctcttg tataaataaa taatggtgtt aatacaccaa
     5341 tgaccaaact tgctaaagta gctccaacat ttcggaatgt cgatagcatt gttctttctt
     5401 ctgtaataga agtaatagct gatgccattg atccataagg aatatttata gatgtgtaaa
     5461 aaatactccc ccataatata tacgtaacat acatgtatac taccttaacg ctcatagaag
     5521 ctgaaatcat agaagtttga tacattaaaa aacttgctaa agcgactgga ccactcattc
     5581 ttaaaatcca cggtttaaac ttaccctgct tagttgcttt cgatctatca acaatacgcc
     5641 ccatagttac atcagtaact gcatcgataa atcttgctac taaaaataat gttccaacgg
     5701 cagctccgct tatccccaat acttttgtat aaaagatcat taaaaaagaa ctagcaaaaa
     5761 tgaaagtaaa atcgtttcca aaatctccaa acatatatcc tattttgtct cttataccaa
     5821 attttctttc catacaattc tctcccttct gttgttaagc gttttcattc tgatgaaagt
     5881 acgtactata ctctgaagcg taaagagtca gtatttattt tttacatttc agagtattat
     5941 ttgttttttc tcctaataat tctttatctc ataaaactta tctatatatt tactagctac
     6001 tcgacttact tcttcaaaat cacctttttc aacagaagcc aataaattcc cacctacacc
     6061 aactgcaaca actcctactt caaaccaatc ttctaagttc tctatactta ctccgccagt
     6121 aggcattata tttacgtgtg gtaatggagc ttgataggct tttacaatgg atggaccaaa
     6181 agcagaacct gggaatagtt taatgatatc tacgccagca gtaagtgcct cctttatctc
     6241 agtaattgtc atacaacctg gtaaataagg aatttgatat aaattacaaa tctcagctgt
     6301 ttgtcgatca aaagatggac taacgatata ttctgcccca gccataattg cgatacgagc
     6361 agtaaacgca tctaaaaccg taccggctcc gattattaca tctttttgat cagcatattt
     6421 tttagcaatt tctttgatta tttcttcagc attaggaact gtaaaagtta gttcaatccc
     6481 tttaattcca cccgcaataa ttgaatttat tgctttaatg gcctcatcct tatttttccc
     6541 acgtacaacc gcaatgactc cagccgcttc taacttactt aaaatttcta cttttttcat
     6601 atctatctcc ttcctttatg gatacatact ttgtctagct gtactaactt acaaagaata
     6661 aatttaagct tttatttcaa gtattatttt ctacttccga tttcaaaaaa attaaaataa
     6721 ttatacgcat tacgataaca aatattctcc actatctgac taagatacat ttcatcatct
     6781 ggaattcggc ctgctttaac ccactcgctt agtaattgac ataatactcg acgaaaatac
     6841 tcatggcgag gatagcttag aaaacttcga gaatcagtca acatacctgt aaaattcgac
     6901 aacaaacttt gttgtgccat cgtagtcaac tgttgacgca ttccttcagc tgtatcattg
     6961 aaccaccaag cacatcccaa ttggattttt tgaatcatac ccccttggaa gctttgcatt
     7021 gctgttgcta gtggaagcca atcagttgga tttaatgaat ataaaattgt ttttggtaag
     7081 cacccactct tttcagcggt atcgaacaat gctacaacat tttgtgtcaa actagcttga
     7141 tcccccatcg aatcaccacc gacatctact ccaatttgtt cctttaatat acttgaatta
     7201 tttcttaaag catttaaatg catttgcatc gtccaaccat atcttgtata ctcagacatc
     7261 aaatgtaatt gaatacctgt aacaaattgt gcaatttctg ataaatggaa atccgttttt
     7321 cctgctaaag cttttattaa cagattgtcg agtatttttt catctgctat ttcataaaaa
     7381 taagtattca aaccgtgatc tgctaatcga cagccaattt gatgaaaatg atccactcgt
     7441 tggctcaatg cttgcttcaa cccattaaag tctttgattg gtatagccgc tgtttgacta
     7501 agttttaaaa tatagttcga aaagcctgat gatttgatac tccagacctt atctggacgg
     7561 aaagtaggta ataccttgaa agaattatcc tgtttagaaa gctcagtatg ataccacaag
     7621 tcatctgtag gatcatccgt tgtacagatg gctttcacat ccatcatctc caacaattct
     7681 ttcgggcgat aggaatccgt ttgaattttt tcgttagcac gtcgccaaat ttctggtgca
     7741 ttcttctcag aaattgtcaa atcaatatca aagtaacgtt gtaattccaa atgagaccat
     7801 tcaaaaatag gattacctgg cgccttctcc actgttttta caaaagctaa aaatttttca
     7861 taatcatcac ctggaccact gatcaactct tcttctatac cattagctcg catcaatcgc
     7921 catttataat gatctccagc tcctttatca tttaaccata cctgagtcaa attcttgtat
     7981 tgcttatttt ctagcaaata tgctgggtct aaatgacaat gatagtcgat aattggttgg
     8041 tgttttgcaa atttatgaaa aagtctttta gctatttcat tctctaataa aaagttctta
     8101 tctaaaaaca tatttaaaca ctcctttcct tccgttagtt tttagaagag aaaatttttc
     8161 ctctaaataa actcccttat ataattattt actcgccccc ttttcaagcg cttcccaaat
     8221 accatttaaa taaactgcac ctagagctcg gtcatataat ccataaccag gtctaccggt
     8281 ttctccccaa atcatccgac catgatctgg acgaatatag ccattaaatc cattatcgta
     8341 cattgttttt aatatcttat acatatctag agaaccatat tctgatttat gcggcgcttc
     8401 gtaaaaatcg agtccattgt cacttaaata tttgatatta cgaacatgtg caaaaggaat
     8461 ccgatcccgt tgacaaaatt cagatagaat ttcatagaca tcattatctg gtcgttctgc
     8521 aatacttcca gtacataatg taataccatt agaaggagaa tccactacat tacacaacca
     8581 atctaaatcg tcacgatttt taacaatacg aggtaatccg aaaatggaat atggtggatc
     8641 atctgggtga actgccattt taatcccaac ttcttcacat gccgggataa ttgctttgag
     8701 aaaatatgca aagttctctc gtaatttctc ttcatcaact tctttatagg cttctaataa
     8761 ttgcttaatt tgtgataacc gatgaggttc ccaacccggc aattcaaaat tattagtaga
     8821 attttctact tctctaataa tttcctccgg atcagtaggg atattttttg aaatataggc
     8881 taacgtagaa gacccatcat ctaaacgata atccaaatcc gattttaccc aatcaaatac
     8941 tggcataaaa ttataacaga taacctcaat cccaaattct gccaaattgc gaatcgtctg
     9001 tttataattc tcaatgtatt gatctcgtgt tggtaaacca attttgatat catcatgaac
     9061 attaacactc tcaataactt tcaaggtaag tccattggct tcgacttcat cttttaaaga
     9121 tttaattcgt tctctcggcc aaacctctcc ggctggtata tccattaatg ttccaacaat
     9181 tcctttcatt gctgggatct gacgaatttc ttgtagtgag attttttctt catttgcccc
     9241 ataccatcta aaagtcattt ccatagttac tttcctccaa cttctgttat atatttattg
     9301 attgttttac gaactgcttg aggacctact agcatttcgc aaaagatttt ttcagttttc
     9361 tttcctaccc caacttgata taaatctaaa ccaaagattt ctttattttc taaaatttcc
     9421 tgtaccgcac aatgaatctt tgaaggatct tgttcaccta atttcaatac tgataattta
     9481 tcctgcaact ctaccaataa cggatcagga cttggcacaa aattttcccc ttgatcatcg
     9541 actgccagta aataacgtaa ccaagcagca atagcgatag gaataaatgt tagattttct
     9601 gcatttccgt ctttttcgac atacttttta attgtttcac catagcgaat cgctactttt
     9661 tgagaagtat ctgttgcaat tcgttgtggt gtatctggaa tatagggatt aggcaaacgt
     9721 ttattaatta cttcatcaat aaattgtttt ggatcaataa tgcctggatt ttcaactact
     9781 ggtaaacctt ctaaataacc tattcctttg attaaaccaa ccaaatcatc atcctgcatc
     9841 tctgctgaaa ttgattgata tcctagcaga caacctgtta ctgccaaagc agtatgaagt
     9901 ggattcaagc ttgtcgtaac cttcatgatg tctgctttat caaccgtctc tctatctgtc
     9961 ataatcacac cagccttttc caatttaggc cggccatttg gaaaactatc ttcaataact
    10021 aaataatgaa ctacctcagt attagtgaaa gcagcaatat tggtatgttt ttttgtgtga
    10081 atgatatcta aatcctcgag ccccatcatc aatagatctt cctttacatt ctctgaagga
    10141 tttggcgtaa ttcgatcaat catactccaa ggaaaagtca ctttttcttt atcctttaaa
    10201 taagcaataa atttttcaga aacatatcct tctttttgcc aagcttctgc aatcgtaaaa
    10261 atactatctt gaaaacgttg accattctgt gagaaattat cagtagaaac catcgcaatc
    10321 ggcaactctc cagcattaaa tctgctatat aacaaggatg ttacaatact catcgtatgt
    10381 tgaggattgc taggtccaga tttgatatca gctttgacta ccgaaaagaa ttgcccttta
    10441 gaatctttta aactgtaacc tttttcagta atagtaaacg ttgtaaactg taatttagga
    10501 tcttcaaaat atttaaccac tctttgatag tccgctatat tcttcggatt gcaatataaa
    10561 ctatcagccg ttactgccaa aagtcttttt ttgagttcac catctccact cataacaatt
    10621 tccaaaatgt cattgttata gtcatgataa gctttttcca ctacttcttc atcaaatgtt
    10681 tcacacacaa ctactcctgt ttctaattca ttttgatctg ctaagcattg agcaatttct
    10741 gcatgaaatc ctcgataaag atttcctcca ccaaaatgaa gccatactgg atgttgctgg
    10801 ccttcttgct taacttcttt gacatcaaaa cacggcagta gaatctgcat ttcattgaat
    10861 tcttcgatag aattttgcca atttttaatc gaaaccataa ttaacctcct caaactgata
    10921 tgttagtttt gatacatttt atattttaaa acccattgta accgttgtca atataaaaag
    10981 ggaataaact tgcttttttc taccatatca gaatgattgt attttttatt cagaaaaata
    11041 aaatactcct tctttttgga ctgattttat cgaaacttat tttttctttt tttcatgtat
    11101 tcttttattt ttataactag tgtattactt caaaatttga tattatatgg catgaacaga
    11161 attaaaatat cagttaaaat aaaagttaag gagcattgtg tatgacaatt aaaactagtc
    11221 tccaaaatca agcttaccaa tctattcgcc gacaaattat ctatgctgac ttagaacctg
    11281 gaaaaaaagt atcagaaaaa aaattagaag aaacactttc tattggtcgt acaccaatac
    11341 gtgaagcact gattcaactc cgacaacaag gtcttgttga tacaattcct caaagcggaa
    11401 attatatctc attaattgat ttagattcgg ccaaaaatgc tcgatttgtc agagaacatt
    11461 tggaacgaca aattatgtta gagtgttgtg ccaaaatgaa taaccaaaaa aaacggattt
    11521 tagaaactat aatttcagaa caagaaaaag ctgttagtca aaaaaatgct cgtagttttt
    11581 ttcataatga taatttattc cataaagctt gttttgaaat tgcagagcga gaagaagtat
    11641 ggcaatggtt agaaaataac aatacacact tagaacgatt tcgatggcta cgagtaaaaa
    11701 cggaaggatt aaagtgggaa aaaattatgg aacaacatta tcaactattt gaggcattaa
    11761 caaaacaaga tccagaagaa gctaactttc taacatcgtt gcatcttcat ttaatgctta
    11821 atgagcaaaa tattgtttta gctactcatc caaaatattt caaaaatata taacttttaa
    11881 ctctttttaa attaaatggt tgttctgatc agaaaaatat cgcttgtttt cttattatgt
    11941 aatatatttc ataaactatt ctgcataaca actattgttt gtacttttta cattggataa
    12001 ctaattatga ctgctgataa cttttgatat taaactagta tctccaatac aaataaaaaa
    12061 tagatatctt gttcatcaaa attagttcgt ggatacttac cttcatttac atcattcagc
    12121 ggtttcccat tttcttttat tctattattt cattttctaa tagacttggc ttcatttcgc
    12181 aatacttttt ttcaataggc atcaaattgg tgttgtttag atatttagtt gtagttttgt
    12241 gacatgataa gtatgctcct ttttctcttt tccactaata caacgatcaa agggtgcttt
    12301 tttcaaaaaa ctagaaaaat caaaataaga ttcgtatttt gattctatat atcctgtttc
    12361 aactacatct tatatttcac aatagaataa atagcctttt gcatagctgc ttaacttata
    12421 agaaattgca atttacttct tcaaagtgaa aacgaatatg agtaaaataa aattattctt
    12481 cttacagata attaaaaata gcgcgtaaca aaaatcggca ttcaatcaca taattaggat
    12541 tgatgccgat tacttatatt ctacgtatag ttttagtatt cttatttttt atcaccagta
    12601 accaattgag aacagcccta aagcagaata gtcttttatc tcaaaacgct taatttcagg
    12661 cttaggaata tgaataatct tttgagtata ttctttctct tttaatctta ctgaagaaat
    12721 accactgcct atctttttta caaatatttc atttggtgta cagactaata aaacaatatt
    12781 tgtaatcaat ccttgcacta aagaattaaa aggaagacta tttaaaacag ggtgtgcata
    12841 actataacat gtgaagtagt tattttgaac tttaactttt aaaaacttta aaaataatct
    12901 tatttgttct tctaaacaat catctatact catataatca ctccactaat taatctcccc
    12961 aaaaagacac agcattaaga gatataccaa cacaacagtg caaataactc tacatcttcc
    13021 ttcgcaacct tatttcaata aaccataaaa attatttttt aatagaaact gaaaattaaa
    13081 actagaaaaa gtagttttac cgaatgtaag agcatcatca ccatcaatat agaaatacat
    13141 tcttttccag ttacatttaa tttttaaaca aaattctccc caaaaaggaa ctttttctag
    13201 tgaaaacttg gtaatctctt tgtaattaat tcttgttaaa gaataattaa acacttcatt
    13261 tttacttgtt attttttcat tgactataac tagttcatct ggtaaaaaaa ttaaccaaca
    13321 aacatcgaca aacagtaaat gatataatcc atttccacct ccaagcatat tcaatactgg
    13381 tgaacatgcc ttagaaacac gaatatagtt atggtttaaa tagatatttt ctttaaacat
    13441 tgcttgttta aaagccatat gctcttgttc taaacttttc ataaactttt actctaatgc
    13501 acagctagca gcagctgctg caattcctgc tacaatattt accttagcta actctttagc
    13561 tgcagctttt cctaattgtt tttctgcaat ttttaataat aaatccgcag ctttttcaaa
    13621 attaaaagct tttaatgctt caataaaatc tccctgcgta cctatagccc aagccactcc
    13681 tcctccagga agagaattaa tggctacaca tccagcatat cgtttccaat caactttctc
    13741 cattctagga acaataatat gttcataaaa gactcttgct gctcttcctt gttcgttatc
    13801 ttgactgatt cgttcacgaa tagcaccaaa atcctttata tggtatacac catgttcgtc
    13861 taaaaaacca actgtatcaa aataaaaagt taattcatct actaatttat tctttatttc
    13921 taaatcaact gtattcactt tttctgtggc atacacactt gttccagtac taacaaaagt
    13981 acttaaacct aataagaaaa cacctaaaac accaaatatt ttaattattc ttttcataat
    14041 ttctcctcca taaaaaataa gttacttttt aaatatcttg tttatgaatt cattccccaa
    14101 aggcctttta agattgatac agcagtccgt tcacttcttt tagacttgtc atacaagtct
    14161 tttaaatgat cccatatcag actagtttgt ctatctagct tcaatccatt aaacgctaat
    14221 gaacggttca ttttttctat tactttagat aaagctacag aaatttttat accttcacaa
    14281 cgcgcatctt ggatttcaat aatagtatca tcaattagtt tttgaatttc ttgcctatca
    14341 acatattcaa tcttagaaag agaatctttt aaagctacta atgattcaac gatttctttt
    14401 ttctcttcag acattttctt cctccttcta gtgacccgta aagccatgta gagcagagtc
    14461 cattgaacca gtaattacac tatctacaac gccattccaa tttactctac attttccatt
    14521 tttcagattt gtcggtccat acggatagcc tttttgacat tcaatgttcg gattatacca
    14581 gataggatta taccattcag ccgcagaagc agattcagtc gatacaaaca atcccacacc
    14641 aacaaatcca atacacatca cactatagcc aattagtttt ttcatctcgt atccatctcc
    14701 taaaaaatag aatagttctt atagttattc ataagacata ttttttccgt ttttgtttta
    14761 tcctttctgt cctataacaa cttttttcaa gtaaagaatg acatagtttt tcttaaaaaa
    14821 acagtctgtt tttttctatt tcttcggtgt ataataaata tgagtgttca ttttttattt
    14881 taatacgcac tccgtacata ataaatcttg atcgcatcaa tcttttgagc ttcttgatct
    14941 actttcaatt gaagtaatac aaattgagta accttattca ttgtttcttc tccaaataac
    15001 aaatattgat ccggattctc tatatcttgt gtcacctggt aaagtttccc agttgttttc
    15061 atttgtacat gcgggtctac atcaatacta ttgtctttaa tacaacgatc tgtcatatag
    15121 tccctcacag cttgattgcg tttataaaca tctgtgaaat tactccattt tctagcaaaa
    15181 tcttttaaga aattttttgt catttcatct atttgcattt gttgcgctgt ctcgtcttct
    15241 aatgaaccaa tttgactgtt actttcagta ctttgaagag ttccacttgt ttcttttact
    15301 gcttcgattg tttcttctgt cgttctcaat tgtgtttttt gtttttcaga agaaaaccaa
    15361 tgacaaccag taagacctat caaacataac caactaaata ctaaaattat cccttttttc
    15421 acgtttctag tcactgcctt tcttatttca ccttacgaac cagactacga atttttgttt
    15481 gattgtacgt gcgttgatac cgagccataa tccgtccttg ctcggcattc tgttccacac
    15541 tagagaaatg ttgtccgcca tatgaaacat ctgttataat tccggtgtga ccatagattc
    15601 caggagacaa tgcaccacct gcttgccaat tcaccacatc tcctgcttgt aaatcacttg
    15661 gttttgggtt catgattact tgccaaccat aggttgtcca gttataatct tcccctatta
    15721 acatcgcaaa catgtgtcca gaacccatta actgtgggcc acctaattga gatacatacc
    15781 atgccgtacc accataacat tccccattat ttacggatcg tccaatgatc cgatccaaaa
    15841 ccttcgcatt gcctttactt tttcctgcaa taagcgaagt tttttttgtt ggtaggctat
    15901 tccaatgctt gatcgcaaaa gtatcatatt ccgttaagtt ataggacgtt atgatactca
    15961 ttgctcctcg ataatacgga ctcccttcgg taatacctgc tgccgcatag cctccacgac
    16021 ctagaatcaa taaacaactt ccaggatctt tattgcccac acattgatta aagttgcttt
    16081 ggctcgccac cataaagcca taatagtcat aacaagcttt taagttcgga aacttcatat
    16141 agaaaccacc ttcagaacca ccaattccac gtgcagaacc ttgtgggtag ggacaaccag
    16201 gaaaccaggt aatcccaaaa aagttcgtat cgtttcttcc agattgtgac tgtccataag
    16261 ctgattcata gcctaattga gaaagaatca cactcggtaa taactgatac tttacagctg
    16321 caccaactgc tgcttgcgca tgttcatctg tgattggacc acgtccttta atctctgaaa
    16381 aaatcggtaa tccttcggta tattccccat taaaagcgac agctagacct gtagcttctc
    16441 ctccatgctc agaaagttct cctgaaaaaa agaatggcaa tagaaaaaag ggaagaataa
    16501 agaaaagaag acaacctaga caccctttct tcatttcttc ctcatccttt cttcgataat
    16561 ggtttttgga ctgttcgtcc ttttggtaaa gtaaaatcag ttcctggttt tgcgtccaaa
    16621 atcggcagtg ttttaggatc cttttctatt ttttccgatt gctctgttgg cttatctaaa
    16681 gaagaaaatg caggttgtaa cgattttggt gcggaaatcg acggtttact ttcagacgaa
    16741 cgttgccccg gttgttgcac agaacgattt cctgatagag tggctaccga cgaattagga
    16801 acagagtatt ggttcaataa ctgctgcatt gctggataac tcccattttt cgcctgattt
    16861 ttcacttggc gaatctgttg tgaaagagaa ccagcagctg ttaattgtgg cacgggtact
    16921 tttccagaag gcaacggaat cgattgacca acaaaagcga tacctttatt taacaatggt
    16981 tttctttgat tattcccttg ttgcttactc aattgtgcca atgattgtac ctgttgtttt
    17041 ggtcttactg aattcatgga cgaatttgga atcaaaccat ttgaaagacc agaattccac
    17101 tctgttttcg atttggtaga agacatttca ggctctaccc catgataacg aacatgacga
    17161 ccactataag gcaaggcttg atttgaacgc ccacctagtt caaagggatt aaccacttgc
    17221 ctccctttta ccgattcttg tggtgtacgt ttttgttgaa acttttgaaa tccatgtatc
    17281 gctgcagaag cgagtggatt cgttgctcga tacacattcc ctgctaatcc tgcacctttg
    17341 attgccaaat tttgtccagc agttgatagt tgaccaggca gttgtttcat ttgagacaaa
    17401 gaatgacttg ctatgttttt cgtgttgttt atagtttgat ctgcagctcc taaccctagt
    17461 ttctttaata aatctttccg ttttacaatg agtaaaattg ataggagtgc tttgacaaac
    17521 atatttccta aaaaaccaaa aacagtattc attggaatta aatcgtctac tatgttatag
    17581 atcaaaaatg ccaccaaaat aatcacactg taaaaagatt tttgaaacat caagcccaaa
    17641 aaggacttta aggtattcat gagcatataa tcaaatactg gaacaaaaga agcgagtaat
    17701 gaaaaaggaa tcacaagtaa taaacacaac accaacattt gaaagataaa acgaatcatg
    17761 ccaatcacta caagtggtaa tccaatactt agattaagca atggcaccat agaaccaacg
    17821 actgctttat aaacagcttt agttggttga atatagacac gataagcctt ctttttccct
    17881 ctatcttctc ctgcagcagt ggtcactttt gtctcaatat cagataattc ttcacttgac
    17941 gcttccttgg ctagaaattc ttgtggttca atctctgctt gatacaattc ttctaaattt
    18001 gttgtcccat aatttaacaa tatatacgga tcaacaacag ccgctttata ataaagttgg
    18061 cgcacttttt gaatggcttc cttttgtgtc gttggcacta aaacaccatt gacatctttt
    18121 gtcgccaatt catctagact atttgtagca gaaaaaataa agccttctac ctccacggac
    18181 aaatcattta accctttggt aaaagcttct cctttactag gtacgttact accatagcca
    18241 aaccaaacca ttgaaaaaat gacaacgaag agaaatcgaa taaacaccat ttttgcgtaa
    18301 tgtttccctc taaatatacg aagagtaaat agatataaca catacaagac gacaatcccc
    18361 gcaccaatag gatcgtatat ttttgaataa atagtatccg aaaaagtgaa aaactggtga
    18421 attaactcgt tcattgcagc tccttcatag agcttctcaa tgacaaaatc aaggccttgc
    18481 caaatcaatt tacttaaact aaagaacata ttcgtcatca tttttagaaa atctgtgcca
    18541 tttgccccaa ataacatttt gcctaatgaa aattcactat cagataaata agaagaaaag
    18601 gtatcaatat gaaatttccc aatctcatag atcgattgat ccacctgctt ttctgccgca
    18661 tacaccaatc caccaacaaa aagcagtccg aatccaatcg ttaaaaaaaa caaaacgcac
    18721 catttctttt ccttatgctt tatataagcc attgtttcac ctcatttcta ttgcatgatt
    18781 aacgtatcct gttcttctac ttgagagtga cttgtttttt ccgttgtttg taatgcagcg
    18841 gtcatttctt caaacaaact gtgtacattg agttttccta cacgtccata gggatctaac
    18901 atccaacact gtcctttaat catgtggctc atttcagcta agttcgcttc atttacttcc
    18961 aaacgtaaat gattcaaaat cttttctcgc tcactgtctt catcaaaagc aaagacgaca
    19021 ccaaaattcc ctttttcttt atctgaacct aagtcaccaa taaattgtgt atctaacact
    19081 aattgattca tctgggaacg ccccacacgt gccattgctg caataatact acgtcctgcg
    19141 ttcgaattat taaataccca tgcttctgta aaataaatcg ctgttttctt actactatct
    19201 cgttttccaa acatttcaca aaaacgacct aaactaatca tcaaacacaa agactttcga
    19261 tccgcatctg tatatagttc tggtcggaca ttgtcatttg gtaatttcaa atcttggatc
    19321 tctaaaatcg ttgttttggc attaaagtct aatcccgggt tttctccata agaaaatcct
    19381 aaacgtaaaa tcgaatcttc taccgtcaag cgtaaaaact caccatattc tcgaacctct
    19441 ttttgttcca tttgttctaa atagtcgacc acatgcatca agccaacttg ttgtccggct
    19501 tctttttgaa ctaaaacttc ttggattccc tttaataccg ccccttttaa aaggtgattg
    19561 gtacctaacg gacttaactc atcaatcata tcctgggcta cttgtttcgc atctactcgg
    19621 gataaacaaa caattggatc taatacacca taattacggg gatttgtagc atctaacgtg
    19681 acataactca ttttttgcaa atgttctaca aacaaagggt aatgtttctg ataatacggg
    19741 tcttgaatga gtttcgtaaa ccatttgcgc ttttctcctt tgggatccac aaataaactt
    19801 tgtacattca taaacgaact atacaaaaag agcaagccaa ctaaaaaggt cttcccttta
    19861 ccggtttttc cagttactgc tacatgaggc gcatcaaaca acgcaccttt gattccttcc
    19921 gcaatggcta gaagattcaa aaagacaaaa cgatttgacg cataaattaa ttcttctaat
    19981 ggtgtttttt ctcctcgaga accaccatcc cctaatgtat cttgccgacc aatataccag
    20041 ccggattcca tacctaattc tgatactgct gaaaacaacc attcgccaac tgcttctaca
    20101 gttgttcggt gcttccaatg taactgccgt cccaatggtt gccctaataa acatttatag
    20161 aacaattctc gttgatcatt ttttgcacgg tggatatgga taatcgtatg aagttgttga
    20221 ataaccgttg cactattttg acgaacttct tcaaccgttt gaccgtatac aataaaacat
    20281 gcgatccaat cgacgacagg ttgcccatta tctactcgtt gctttaaatg ttttactaat
    20341 cctcgaacag ttaataagcg ttcactaggt tcttcatcat tttgaaccaa ttccttatgc
    20401 tctgttttga accgttccga tagccaattc agttttaaac caatacctcc ctgtcctttc
    20461 aagcgtggat agtgaatttt cattcgcaat tctgctggga aagaaagatc ctgagcaaat
    20521 tgaaatagat cacaatttct catattttca ggtgtttccc caataggcaa caatgctaaa
    20581 taactactcc ctaactcatc ttctaattga agaaggcctt tatgttcctt cggtatacgt
    20641 acatacgttc cttgattgtc tttcagtact tcccaattat tttgttcttc tactttgtga
    20701 gccattcctc gaatatattg cagacgattg agatacaaca gctctttttt tactaaggga
    20761 cgaatagaaa agctataaag taattgtgtc acttctttta cataaggatc actttcagaa
    20821 aacaaagttt ccaaatcatc tacttctaat ccaaataagc gtgctaaact tcctgctaaa
    20881 tctaaccaga ttagatttat tacatcatga aaactctcca ccgttgcttt ttctttgact
    20941 ttgattccta aaataaatga aggacgatag acttgacctt ctcgttccaa caatgtcact
    21001 gtttcttttg cataatacgc accaattgct tgactatcgg gagaaaatcc ctttcctaat
    21061 gtgtcaaact tcgtccgtaa attcattgtt cgtggataca tcaccaactc cacatcttca
    21121 taatctgcta aaagcaacag taaacgagcc atcatttctt ttatttcctg tgtctttttt
    21181 ggtgtgtttt ttgaaattgt tcgtggaaaa acatgatagt aggcccagat acaatcctct
    21241 ccatttaaca aacaattttt cttgaatgct tttactggtt cttttacaag caccaatgaa
    21301 tttcacctcc caataaaaaa ggaacaacca gttgattgtc cctttttcta atcctctaaa
    21361 taaacatact tattcacaaa aagtaattct tccaatgcat tgtttgatac cttgtcccag
    21421 ttataataca cacaatcacc attcatcata cgaatcatat aacaaaacca atcccataaa
    21481 taaaaatgca ctttttttcc atcaggtttt agttttgcca gtgctaacac acataaatag
    21541 gggagtccta tataaaaaac aactcctgct ggtggaaaaa aagaaatgac ccaaccaata
    21601 aatgaacgta aaaataaata ttcaaagatt acgaccaaca aaaaagttgc tgcattgact
    21661 aatgcaactg gaaatggaag acgccaattg cttgtaatct gttgtacgcg ataaggttcc
    21721 gcataaacaa tcgaataatc ataaggttcc caatccactt cactatcctc ctaatccata
    21781 aataattttt caatgatttt accaaacgca tcaaatacac gtgttggatc atttaagaag
    21841 aaataaactg cggcacctgc tgcgatagat attaatgcat ttcctacttt tgatttcata
    21901 aaatttcgca atcccagata aacaaccacc attattaaaa aatagccacc ttgcgttaat
    21961 ataaaatcta caattccctt cagtgtcatt tccgttcttc tcctttccta tccaaccaat
    22021 tatgtgttaa tttttcaaca taatactgat ttgttttttt cgtaatgaca atcgtcattt
    22081 gttctttttg taaaagtgac gtatcaccat ctcgaaagac gaccgttgct tttacaataa
    22141 aaggtttttt cgtttcttta taacgcaata ctttcatctc tacttgatca actttagctg
    22201 tttgattgag tccttcaggt tctttcatca tgtatgacat atcttttgca ttgtttttcg
    22261 catacttatc taagaaatct tccacaaatc cttcaacatc tttcgcttcc gacgcatcaa
    22321 ccgtttcgta taatgtgtca tcataagtaa tcattcgttg tttttctgta ttctttggta
    22381 gtgccgtaaa ataaggataa gcaataatac gacagccctt gtttgaaata gaaaagggaa
    22441 gattgagtac ttgtgtgatt gtcacacttg tttctttctt actctctgga ttcatcgagc
    22501 gaatatcata agttacttta taactagcag ttggaatggt ttcaatttct tttaatccaa
    22561 taaacgaagc agcagttaat tttcgaacac ctgaaacact tcctggttct tgaataaagt
    22621 tttgtgcata aaactctttt tttaatgttt cttgacgttg ttgttcttgt tcatgattat
    22681 cgaatgtatt catatacaaa gcaacaaaac gattcataaa ggattcaatt tcaggtgtgt
    22741 acgttaattc tgaccgactt tgtacttctt tcttttgtaa ttgttggatt tcatctttca
    22801 aaaacgacac ttgaaccttc gttttcatgg attgaaaaaa tgccaagccc cctgaaaaac
    22861 aaagaaataa aaccaaacac caaatccatt tcactgcttt ttttgaatgg attttctttt
    22921 gcttcggtac tttctctgta taaacttttt ctttccgccg tagttgtcgt tttttcataa
    22981 gctactcctt ctagtatgtt tttactagta cgtacgattg acaacgataa gcttgttttt
    23041 ctgaaaaata gtccattcaa ttaccctcat tttctattcc ttttctcttt cttttatatc
    23101 caacaaatcc agcaatactt gtcaacactc ctcctagaac agaaagtgca acatgtattt
    23161 cttcaccagt ctttggtaag acttttgttt ttccatctgc tgttttgatt tcaatattgc
    23221 cacttggaag tttctttaca ggaatcgaca aatcctttac caaattccct tcactatctt
    23281 ggattaatgg aataccatct tttacaccaa caattgtttg atcacctgct acttttaatg
    23341 gggtggttgg tgttggaata tgggtcaatt cctctacatt actagtgaca atcggtacac
    23401 tcattccttg agaagtattc gtcgtaattt caccgcttgg ggttaccgat actgtgactt
    23461 cttttgctgg aacaataggt ttattttctt ttggaattgc ttctgatttt tcaacaggtt
    23521 gtttcggttc ttctttttgt tcttcactgg tagacgacat cgttggctgt tccgtacttg
    23581 acgaatcagt attcttttca gaagaactgg ttgttcctga ttgttccgga gttgtgacta
    23641 tacttgaatc cgttgttgtt gaactatgca caccttcttc ttcgatcgaa tcagtcggta
    23701 aagttgattc aggaaactct ggttctggtg tcactggctc tttttcaggt ttctctgact
    23761 gcaattgttc aggttctgct ggtttttccg ttgttcctcc atttagctct gtctcaacat
    23821 ctggtaatcc ttcccctggc aatgtttcta caatttctga cttaggtgtt tctacagttt
    23881 catctgcata aaccaatgaa ctccctaatt gaaacgaaaa taatgaaatt cctagtgttg
    23941 ttacgactgc taatgttgtt tttttcatga ttattcctcc aattttttat gcaattcgtg
    24001 ttttgttcat agacgccgca ctaatattat ctgaacgata aaagaactcc cgtccgtttt
    24061 cttctaaccc aacatatgga ttatttttga ataattgaat caatagttca ctggtgttgt
    24121 attttggata gtttgcaaaa aaataatact gtgcttgtcg cccatccgaa aattcaacaa
    24181 gtaattcata acgataccgc ttcaatcctt ttcgttgttt taaaggatct ctataccaac
    24241 ttgtccatcg ttccattcgt ggatagagat agacacgata cacatagaac aatgccatac
    24301 cacataccac caaaaataat aatcgccaca taaaaattcc cccttttctt ctacctttct
    24361 tgaatcatcg aacattcata ccctctatag agatttgaaa aatccatcat caattgttca
    24421 tataaacgtt gttgcaaata gcgattgttt cgaatacata attcttcata gccatcaatc
    24481 acttgatctt ctttttcata gcatcttgta gctctatgac gctcagcttg caagacataa
    24541 ccaaactctg caccatatcg ttctactgtt aataactgtt gactacgcaa taatgcaata
    24601 taacaatcac aaaaatgttc aaccgacatt tgatttttct cacgtttgtg aaataggtat
    24661 tctttagaaa gcacattatt cgttaaacaa tctgataaat agcgataatc tggcggtcgg
    24721 ttattttcat ctgtgaattt ttcccataat aaactgattt ttattcgttc agcggctaga
    24781 tagtcttgtt cgcgtggata aaattcatca atcgcacaaa gttttttatc acctgaataa
    24841 acaaatccat ataatgcgaa acgaactctt ccttttcaat tggctctcct aaaaattcca
    24901 gtgacatacc atcttctcct tcctaaaaaa aataaaaaag cagaaaccga tttggcttct
    24961 acttttcttt ccttttatag ctctttttta cggaagaatc cgcaaatgac attttttcaa
    25021 aaaatcaatc ggcacaagtt cacgaaaact tggagcaatt ttggatagaa tcacttcccc
    25081 atcttgtaaa atacaatcat aaaaatcatc agttacttga tacttacgct tcttacaata
    25141 attgataaaa tagtagcgat cattttctat ttccattcgt tgttctacta agcgcatacg
    25201 aacatcatca tagaaataag ccacaaatcg cccttcaagt tcatgttttt caatgggata
    25261 ctcttctggt aacaatctat tttttcgtcg tttatacatt gctggatacc ttagaagaag
    25321 ttcatctaaa cgtctgtcag tatatggtaa ctgacgaatc aacgattcta atcgttcttt
    25381 atacagatag aataattggc gcaagcaata gtgtaccgcc tctggatttt ctaatactgt
    25441 tggatcacgt gaccaatacg caccaacata aatcataatt tttttcattt agacaatcac
    25501 accagcaata ctaatgaccg atccacaata ggtagaacaa gtggcatagc gaccaatttc
    25561 ctctaattct atctcaatct cttctaaaga aagatatgtc tgttcttctg ttggctggcg
    25621 actcatttcc caagtgacag tcaccaatga aatttcttcc ataagaggtt tttcgctgct
    25681 aagtgctgcc acacagtttt catatatctt cattttatcg cagccttttt taaccgctaa
    25741 aatcgcaggt attggcaatg aaaatcgata aaagcgaatg aattctagcc ttcctttcct
    25801 tcggctaaat tccaactctt cgagttcttg ttcgtatccc ttacgaactt ctaataagcg
    25861 tgcaatttct tgccagttct ctttttcctg ataacgtcca gcttttaccg cttgttcaat
    25921 ataaggaact cgaaaacgaa aataagacaa atcaaccatc ttttcattta atgcttcgat
    25981 tgcagccttt aaatccaaca ggcgcagcca ttctgttgtc gtatatgcat tcatgcaatt
    26041 ttccctcctg acgttcccat ccattctaga tagttttgtt gctcgtcatt tagttcggca
    26101 ttatcaatcc cttcttgtac aaagtctctt cctaaaatac gatctgcttc ttgtaacaac
    26161 tttaatgtcg gagctacttg tttcaaaaac cagcgttctg aacgatctaa tgagaatttt
    26221 tctggcttta ctgtaaaatc caattcttcc atcgaacgaa ataattttgc ccatcgttta
    26281 tcaacaatcc gtgcatcact ttccagtcta tcccaaacaa taagttttgc attaattaaa
    26341 ccaacgccaa tctctcctaa acgtttcggt gaatcaccta aaataaatgc ttctactgct
    26401 tgtgttgctt tctcattggc taaccgtaac tcatatcgat tataaatacc atatttcgtt
    26461 aatgcttcta attctgaaat tttttctcgg ttcgcaattt caaaacgttt ctcataaaaa
    26521 ttaaaaaaga gaggactctt tcgcgatcca aaatacaaag ataatccttc acttcgaaaa
    26581 tagccatcat ctaaaaaaca accgccaata ttctggaatc tcttaaagtc catttctaat
    26641 aaacctgctt tttgtttttc tagtaattca aagagatcga aatgttcttc cgtttccaat
    26701 ccccaaagtt catctaacgc aatatcgaat cggctacatt gcacacgtgt ataaccagct
    26761 tccaactttc cttgattttt ccaaatggaa tatagccatg ttcgccaatc tgtttgttgt
    26821 tcacgcatga cttcctcata ttcccggcaa ccttgtcctg aaaattgcac aagtacattt
    26881 tctgttacag ttcgttttga atgccagaac acccagatat tcccacgaac agaaagacag
    26941 tcaaaaagat acaagcccgt tggacgtgtt tcaaattctg tcagatccat tcgtaataca
    27001 cgttgaatca ctgttttgta gtctgtccca aaaaaggaaa gacgcaaata atcaatcatt
    27061 gctcgaagat ctattccgct tttcatatac aatcgaaagc gttccttgat tcgttgttca
    27121 aaatcctctg ggatttttct tttcccttgt tccatctttc taatgtaatc ttttgagcag
    27181 cccatcaatt gcgcaaatct tgcttgtgat agcggctttt tatctccact tatattatga
    27241 attgcactta acttctttct gtagcttttt agctcaatcg gtgtcatttt ctcgctcctt
    27301 ttataaaata acaaaatcga ttttttttaa ccctttagaa acaccgatat atcaactagt
    27361 ccccctcgtt ttttgggaaa agtagtacaa ctgctgacct tagataatca cttgatacaa
    27421 aagggtttat aaaacttttt tctatgtgtt atgttatttc tgccccccat attatatatc
    27481 ggggggcttt acacaaagag gccgtgcgca agcgcacgac ctctttgtga gctgcacacg
    27541 ctgctagcga gtgcgcatta taggcccatg cttcgcagcc ttaatgcgca ccgccaggca
    27601 gagtgcggct accagactac gtctagagcc ctcccgatag ataataacta caaaattaaa
    27661 tgatctaatt ttgttatttc actatatttt tcaggagaaa aaacgcgata aattgacaaa
    27721 gttaaatcct cttctaaatc tactcgataa tgatacaatc gagtcaatcg ttctatatct
    27781 tttttcgtta gcaatacttg attaataact tttcctgtaa aaacacgttc tttgcgcaaa
    27841 aagcggtaat cagttacttg ttcaatacga ttcaaccaat cataaaacgt tctggaagaa
    27901 agagaaggat taatcattcg tattgctgta gctactctat aataacaact ctctgccatt
    27961 taacttcacc tccttagttg attacaaaat atgcgcatca gaaaaacttg ttccttttgg
    28021 atcttttgct aaatacattt ggcgctctag ttgttcttgt aacaactgat tatcatctcc
    28081 catcgtttga tcttgactat cctcttttac tgtaaaatca tagacaatca tttcagtaaa
    28141 tttctcaaat tctttgataa agtgataatc tttgtaaaca aatggcgcaa aaaactctac
    28201 aggtacatca aatcctggaa aagcatatcc acgaccaggt tgatctttgt tgtaaaatgg
    28261 cttattttta aaatcttctc caaaagtcat taaataacca atgggagaca atcgaccaac
    28321 agaaatacgg aatgttaaat tatcccgaac accacttgga aaatattctg catctggtcg
    28381 ttgcattgct aaaataatgt acatccctgc ttgacgaccc tttaatacta atggctgaat
    28441 caatttatcg actctatttc tcgcttccat atccaacgaa ccataaaaag ctgcccattc
    28501 atcaaaaaag ataaaatgcg gtggtaaccc ataataagca taatttttcc ctggttcata
    28561 tttaggatct ttcatggttt tcatataggc ataccgttga ttcatttctt ttaatgcatt
    28621 tcgtaaacaa ataatcattt cttcatttat tttgtaaaac acatgtcctt tgaatacatc
    28681 gacgtcacct aatgctgcta aatctgccgc ttttccatcg caaatatcta ctgtcccaac
    28741 acttaaacaa gcttgaatta aagaatacaa taaataggtt ttcccaccac cgattgcacc
    28801 agcaatcaac atatttggtg attgatcata tacccaatcc aaagttttca ttaaatgaat
    28861 acgtccattt tctgctatac attgatcaat aggaatccga ccagaatctg aaaggaatac
    28921 ataattgatt cgggcttttt ctcgttcttc acgaattaaa tcacgcaaaa atacttcaga
    28981 taacaaatga cccattttta aaaatcgttc gtgaaaacgc ccaccatcta aaggaaaaga
    29041 aaccactaat tcttgtttct tttgataaaa ataaactttt ggtaatctca ttttttccct
    29101 tgtttgtttc tcactaactt gtttctttgt ataaacaaac cgattgtcaa ttaacattcg
    29161 aacaagtaac tgacgccaat aaacagaggc aaaatatcct tcttttagtc gcgaccaatg
    29221 catcaaccct aaaattaacc cactaaccag caacaaatac aacacaatac ttattccagg
    29281 aataagatac atttgccaat tcgaaaacgt acttaaacgt ggataaaata ctttccaact
    29341 aaaccaacct aacagaatca aaaatggaaa caaaaagaaa ccataatagc aaaaccataa
    29401 ataacgattg aaatagcgaa ttcgccgacc acgatacttg aaaaaatgag ctttcaattg
    29461 tcacattcct cctttctgtt tttacttttc ctgtgctaaa aacttttgac aaaaagcaac
    29521 taatacagga atatcacatt tagtaaaaaa acataatcga aaaagattta atcgattttt
    29581 ataagggtgt gcacacatat tacatattcg tactatacga atccaaatca cttcctgatg
    29641 atcttgtttc cactggtacg gtaatgaaaa acgaacaaga tcacgtaaaa acatacactg
    29701 cccaataacc gcacaaatat atgcatttgt ttgtacaaaa atcgttggat tgtctccaaa
    29761 atactcaatc aattgttgga tattttgata acaagcacaa tctctcaaag tatttgattg
    29821 gttttatctg aattcaaaat ctccccttcc ttctatctta gataaaaaga ataggaagac
    29881 tccttcctat tctttcaaaa aaaccttatt ttttctcttt ttccttagaa tcaacacttg
    29941 gttgtttttg atctaaacct ttttcttgtg attgtttcat attaggatta tttgttggag
    30001 cttctacttt ctctaatcct ttcgcataaa tcactaaatc tgaatattca cgattgccat
    30061 cttgtgctgg aatatatacc acatgatatt ctggatcaat taatttcaca ggatcacgtc
    30121 gtttaaaacc agtcaaatct acatctgctg gaaatttaac tcgtcgtgca atctttggtt
    30181 catctggatt tccaaaaact aattgtgctc gctgtgatcg aatttctccc gtataatcgc
    30241 ctgtttcatt atcaaataca cgatcagact cttctaatgc gccaaagcgt acggctccta
    30301 aacaagtttc atctaatgct tctgtaatgt cataattatt tggaaatttt aatcccatct
    30361 tacaaaacct ccccaatttt tacaccagtt aaaaagacac caacatcttg atagccagtt
    30421 gttcgacgct ctgtttgtcc catatcattt gtttcacgac tattcactcg ttctttacga
    30481 aaaacaaaat aagcttcttc aaatgaaata cgcacctctt tttctggtaa tcgtaatctt
    30541 ttatcctctt cagctgtgag ataaacaaaa aaagcaggct gttcttctcg cgaacactct
    30601 gcttgtaatt gaacatatcg cccagacaca ccattaattt cctttggtgg attaggttcc
    30661 cgtgaaccca ataaaaatac ttgacctaaa aactctttct tcatacgcaa tgctttttct
    30721 gccataaagt ttttcctcct cttaaaaacc aaaataaatt ctaaatattt ctacattaca
    30781 atcaaacaag cggttaaaaa tcctaaccgc ttgttcctca tgactaatct ttggctttac
    30841 gtactttata aagtgttata cctaaagcaa tgactaatac tactaatcca agaaccataa
    30901 gtatactact tgtttgttca cctgtttttg gcaacattgg tacaacagta gctggtttaa
    30961 cccgttgttc tggtttcact ggttgcggtg gttttggcgc ttccacaatt tgaaccgttt
    31021 gatctttgtt tgttagatct acattgtgtt tcgccacttc ttcaaacgtt tctttctcat
    31081 cttccgtttt cgcttggagc cattccgcaa aactcaagcc ttttcctgca agattgcgac
    31141 cgtccactaa gaattcaaat aagaattcca tcatttcttt atcggccgca aagacttttt
    31201 ccgcatgagt gccttcaaat ggtgtgccgt ctggtgttaa gtagccttga acaattaagc
    31261 gatagatttg accaatcgca agaccgtcta ctttgaccca ttcaagcaca gtttgatttg
    31321 gcaaggccaa gatctctttt ccgccatttt tattcgtcgc tttcgtcgta atggttggat
    31381 tactgatttt gatggtttgg tcattgtcgg taatatctgc gtgagaagcc aataatacgc
    31441 cttctctaaa cagatcttca aagaccacga cttctttgcc tcgcaacgca cgtgcgtcta
    31501 gaataaagtc tagattgact gtaccatccg ttgtttctgc cacaaacgtt aaggtacttg
    31561 tgacttcttt tccatctact agcactggtt tttccgttac tttgtccatt agaacaccgt
    31621 tgactgtgta tgtttttcca acgaccaaat cgtggtattt cacagcgtct gtaatggtga
    31681 ctttcgttaa tggattaacc tctttcaagc cagtgggttt atgtgtagcc gttgtacgta
    31741 cacttgggtt agttactcgt accgtttgcc ctttgtcgtt gatgtcttta tggtttgcta
    31801 gttcttcatc atttctaaaa agactttcaa acacgacgat ttcacgacca tttatacctg
    31861 tcaaatcaaa ggtaaatggt acgatcaccg tttcattttc tgctttggca ataaagccaa
    31921 cactcgtttc taccgtattt ccatgcacaa gcaagggttc accggttgct ttatccatta
    31981 agatcccttt gaccaagtat gcttttcctg gaagaatctc ggtaatttca acggtatcgt
    32041 ttaaggtaaa caatcctgtt gggtctgcga ctgtcaatcc gtcttcaaag acagccgtgg
    32101 tatgaacggt tggattattc actttcacac tttgggcttc atcgttgata tccgcatgtg
    32161 ctgcaacttc aatgccatca cggaaaagtt tttcaaaaac aacgatcgtt tgacctttca
    32221 gaacactagc attaaccaca aattcaaggt cttttgtgcc attgactttg tctgcaataa
    32281 aggccaaggt acttgtgatt tctttgccat cttgtaaaat tggcgcattc gttgccttgt
    32341 tcatcaatac tcctgaaatg gtgtattctt ttccgacaaa caagttggta taagaaacac
    32401 tgtctttaat gacgatcgtt tctaatggat caaccacttt ttcaccatcg gctttatttg
    32461 acgcttgtgt ttctagtttt ggtggaatca agtaattacg tacagaaacc actaacgttt
    32521 ccccatcatc tggcgcattt tgtttgaatg caaccgtgaa tgcttgttta tctgtatttg
    32581 gttggaaact ttctaatggg gcattttcca agaagtaata gtcatcggca actagacctt
    32641 tcactaaaat ttccccgttt tgatcagtgg tatattcacc aattgcttga tttttaccgt
    32701 tatacaaggt aaagttcaca cctgcgagcg gcgttttctt cttgttccat tcttcatact
    32761 tgaataattt tacacttttc cgtgcttgac ggttcgcaaa atggatcact ttgatcggtt
    32821 ctgtatcatt ggtaatcgag aacactaatg ggttttgatt caaaacgtaa tttacggggg
    32881 ctttgatttc ttccaaacga tagcgatctt ttccataagt aagtgtaccg ttagttagga
    32941 aaaagccttt ttcattggtt ttaaagatat ccgttgtttc tgtatcattt ggaatctcca
    33001 ttgtgacata acgattggct aaagtatcaa aaatcttgaa ttctgtatta gcaagtggaa
    33061 tcacttttcc tgtttcttga tccactttca ccactttaag acgttgttca attactttat
    33121 cttctaaaac ataatggaaa gtttgcccat tttcagaaat tgtgacttca agtggttcaa
    33181 atagtttata cccttctttt cctttggttt cagaaagaat gtacgtatca aagacaacgg
    33241 tatttttacc aaaagtagca taaccatcat tgtctgtcac aacggttttc accactttgc
    33301 cagttgtttt tgacgtcaaa gtgatttcaa tgccagctaa ttttggtttg ttatctggat
    33361 tcgttgaatc gactaaatct ttattagcaa ctttcactaa atcaatggtt cctttgatca
    33421 cttgatcttt tgcggtcgca ttgacagttt ttccaggttc aacaacaatt tcaattgctt
    33481 catcagaaag cacataacct tttggcgctt tgatttcttt taaaacatat ttgccaggat
    33541 caagatcttt aatttctgcc tgtactttgc cgttaatttt tttcaaggta atttctttaa
    33601 tctttttccc atctgcttga tacaaaccat agaccgcatt ttctaaagaa gctgcacctt
    33661 gtgctttcac accagtttcc gcatcttctt taaacacacg aatgtttcct tgttttagaa
    33721 tttgtaaatt aataacagac gcattaggtt ctgttggatg taacacacca attgtttgag
    33781 ctcctggacg acgataggct aatggcgcac cttgaacttt aattttattc aattgaattt
    33841 ttgctttatc cggtgcctct tttgtgactg taatccatac ttcattgccg tgaatagata
    33901 cattgacacc ttttggtttt tgaatgtctt tcacatattt caaaaaatca tttttattct
    33961 ttactttcaa cgtttcgcca atttttaccg tatgtgtttg attattaaaa gttgcttttt
    34021 caccaaagtt attaatcaaa cgttgaattt ctgcttttcg acgatcataa tcaacacgga
    34081 tatttttgat tgggattttt gtgcccaaag cttcccaaat cataaattgt gccgcaatgt
    34141 attgttcatc ggatttgtct ttatttgtga catatcctaa ataagagatc aagcttgttt
    34201 ttttccgtac atttgaattt ttcaaatagt ttttcaaagc agtagctgta taaacttgac
    34261 cttctgcggc tgagacacca ggctcaatac aaaacgccac ttgtccatta atctcaaaac
    34321 gaaccatata atttaaagtg aagtttagat tgttcggact agaagtaaca ccaatatttt
    34381 cgccccaatc aattttccga ccacctaaaa cagctgcatt ggttgcacgg cgaacacgaa
    34441 ccgaacgatt ggttggtact gttactaaca gtgtaggtgt acctgttttt ggaatgttct
    34501 gctctttttt cttttgattt tcaatactag ccgtagattc tttgtttggt ttcgttggtt
    34561 gattttgact agctgcggtt gaagagattg ttttttcaac gttttcctca ttttttcctt
    34621 ctttgtcagc agtagccgct ggttgttcca ctgtttcttc tattcgtttc ttttcttccg
    34681 cttgtttctc agaagactct ggctgcacag aaggcgttgc ttcggcagct ttttctcctt
    34741 ctagagtgga cgtttctgaa gcaggggttg taattgaggc agtttcttca actggttgtg
    34801 aagtaccagg actattccct gggtgttgtg tttccccaat cgtctgatcg agagtcgttt
    34861 tggaattgac cgttggcgct tctgtcacag gggcctgttc aacagtggct tcaccagctg
    34921 ggaccccggc ttctgctggt tggacttctg tcacttcaga agcgacttgg gcaatggctt
    34981 ccatcgtagg ttgtatagcc gtcgtttctt ctgcatgtgc ttgagcagtt cccaccaaga
    35041 aacagaattg agaaaaagcc accaatgcga gtgctttcaa ccaattcatt ttcgtttttg
    35101 catacacaag aattcctcct tttcctgaga attttatata ataaaacaaa acgccgttac
    35161 caaaagtgat aacgacgtga actgtctctt ctatttttat ctggcgctct tatctgaaca
    35221 catttcatca atgattttac cctcccacta taattacaga acaaaaaaag aacctgcttc
    35281 gtggaaatca actgtccatt tcccaattgg aataccagct tttttggcaa cttcaccatc
    35341 accaaatctc atgccatacc aattactacc ttcatcctta atttctttcc aaccatatga
    35401 catagcttca tctaatgaat caaaaatcat gacactattg ccaattgtta caggatctgg
    35461 cttaagatct tctggaagag aaatatcaat cataccataa tgatccgatt cctcagtatt
    35521 attgtcatta ctagctactg gtttggttgt tctactggct tattttgata caacaagtac
    35581 tcttattctt cttttacttc tccgttttca atttcccatt caaaccactc cgcaaagtct
    35641 tgcttaaaac catctactcg atacctattt tgtaaatagg catcttctga cgtcgtagga
    35701 tctaaatagg taggtttatt ctctggacga gcatagacac ctacccatgt ttcgtaatct
    35761 ccttcaaaat aactatctac caaatagcct ttttttctaa gaatctcccg aacttgattt
    35821 ttaattattg atacttgttc aaaaccatca ctcattctat cacctcaaat aactctagat
    35881 tctcataaat attcccgaca atttcaatcc tatcaatgat ctctaacaaa tcgctactta
    35941 tgcttcccca ttcgtataag aatttccctt ccgcaaaata aattttccat aaacttcttc
    36001 atgatcgtcc caaccaatat cactctcgaa aaattccacg ttgttcttat cttttagctc
    36061 agtaaatgcc ataagttcaa catgttttcc aacctcgaaa caatcacacc acccatcaac
    36121 cgttacacgt gtgccttcaa tacctaagaa actttgtcct cgtgtattaa acactaaaac
    36181 tttccgcatt ttttgctcat taattaatca cgcgcgaaat ctaggaatca caacttattc
    36241 gcttcttctt tataaataaa aaaactccaa taatcggaaa ttactatctt ttcctcattc
    36301 cttttttaaa tcttcatact tcttcttatc tttgtcctaa cctaataaca caaattttga
    36361 agaaaaactc agtaaaacct gattcttttt ttatcttcac aacaaccaac tttttcttca
    36421 gatcctttta ctagaacttg tatacaaaaa ttgttgaatg ctgatataat ttgcggctac
    36481 ttgaaaaaac gatagatgta aaaagataaa tagaatcatt ttttattcta tatcagtcta
    36541 tgattcattg cttatcaatc acccaaccca ttcgatgccg ttttttttag agaaatttaa
    36601 aaaagaccgt acgaatctcg cattatccga ttacttttcc agaaaagatc cccaattctg
    36661 tataaataac cctatcttct tgttggtttc attttctcat ataagaattc agtcaatcta
    36721 cccactatga ccattactac gtccaacaca actgacatat taaccacgta agtattccct
    36781 cacagatctc cgaatctcca tggtatggat tcccatcctg acgctgcaga ggacaacata
    36841 tttcatgtgg ctctgtaccc ttttgatttg gaaacactac aaatcaatac tcatctataa
    36901 cttatcaagc gaactttcgc taggcttcta gtgattacta aattgttgga taacatacat
    36961 agcccatttt atctagctgt tattcataac agttagttct tgtattactt cttccgcttg
    37021 tgttgccatt gagcttgtca aaaagttact tagaaaaaag ctgccagtaa agcaactttc
    37081 aacaaaccct ttttgtttct tatcatatca agaaacctcc ttttataaat tttttctata
    37141 ataaaaaacg tcgataactt aataagtatc gacgtaaact atttttatat cccgtaaatc
    37201 aaaaattcta aagaaagatt tcctatataa gcatattgga taattcgatt agtattgggt
    37261 atatctctac cattctcata cctatctatg gaccattttg aaattgaagg agaaaaaagc
    37321 tttccaaact cctccctttc tagataataa tctttcctaa ttttcctcat ccttaatccc
    37381 atactaaaag aatttatctt tttaaaatcg ctaactcttt catcttttgg aagtatattc
    37441 ttataatctt ctccgtacat aaggtaagga acagtgacct taccaagata ggcaatattc
    37501 attagttttt caatatctgg aatattaata cctttttccc atctacttat aacatttttg
    37561 cctgtataga tggtaaagtt tttaccaaat ttttcaagcg tctcttcccg gttctttcgg
    37621 acttctcgta ttctttttcc cataacaatt ttatcgtctt ttgataaact aaatatctca
    37681 ctatcacgat taatctcctt caaaatttct ttttcattac ttaatagaaa aatatcgatt
    37741 ttttttgcat ttcttttgac ggatttctct ttctatttaa cacataactg agtaatactt
    37801 cactaattcc tatattatca gctaactctt tgttaagtaa cttattcata tctctgtatg
    37861 caattagttt accgatgaga atctcaatct tatcttcctc atcttttatt agagtttcta
    37921 tattcagaat cttgcttaga gtattatcta cgtctttagg gatttttctt gacccttttt
    37981 catatttaac taaagtactt tgtgaaatac ctgctaaatc agctaacttt ttttgagata
    38041 gttttttctc ttttcttaga gatttaagaa cccttccact tgaattatca accatgaaaa
    38101 aagcacctcc tatgagatgc tttcatcata tactgacagc taaaaatctt caagaaaaat
    38161 attccaattt tgttaatttt agtatcgccg tgataaccaa atgacagttt aaaatctttt
    38221 atacagataa tcctcagtgt tgcatctact caaaaaggtt tatttaatag gtttttcgat
    38281 tgattataag ttatttcaca ctatcttgct catccatttt cagaacggcc atgaaggctt
    38341 cttgcggaac ttcgacggag ccgatttgtt tcatccgctt cttcccttct ttttgtttct
    38401 ctaagagttt acgtttacga gaaacatctc caccataaca tttagccaag acgtttttac
    38461 gcaaggcttt gatgtctgaa cgggcaacga ttttttgtcc aatagctgct tggattggca
    38521 cctcaaattg ttggcgtggg attagttttt tcagtttttc aacgattgct tttccacgtt
    38581 cataggcaaa gtctcggtga acgataaagc ttaatgcatc gactttttct ccattcagca
    38641 agatgtccat cttcactaac ttgctttttt gataaccaga catttcataa tccaatgagg
    38701 catagccttt cgtgcttgat ttcaatttgt cgaaaaagtc aaagacaatt tcagaaagcg
    38761 gaatattata gacgacattt actcggtaat catctaaata atccatcgta atgaattctc
    38821 cccgttttcg ttgagaaagt tccattactg caccgacaaa atcatttggg accatgatct
    38881 gtgctttgac gaatggttct tctacatcct gaatcgttac aggttcagga aaatctgccg
    38941 ggttatctac tgtagcagtc gtaccatccg ttttattaac atggtaaata acggatggtg
    39001 cagtcgtgat caattctaga ttgaattccc gttccaagcg ttcttggacg acatccatat
    39061 gaagaagtcc gaggaatcca cagcggaacc caaaacctaa tgcttgagag gtttctggtt
    39121 cgaattgtaa agcagcatca ttcaattgca gtttttctaa agcttcccgc aaatcgttgt
    39181 aacgagaagt atcaattgga taaagaccac aataaaccat cggattcatt tttcggtaac
    39241 ctggtaaagc ttcagcggca ggattgtctg ctaacgttac tgtatcccct actcgtgtat
    39301 cttggacagt tttgatactt gctgtgatat aaccgacatc accgaccatc aaaaagtctc
    39361 tagcaactgc ttttggcgag aagaccccga cctctgtaac atcaaatgtt ttgccattac
    39421 tcatcagttt gattttgtct ccgggtttga ccataccgtc cgtgatccgg acatttagaa
    39481 caacaccgcg gtaactatca taaatagagt caaagatcaa agcttttagc ggtgcatcta
    39541 agtctccact tggtgcagga acatattcca cgatctgctc gagaatatct tcaatcccaa
    39601 tccctgattt ggcactggct aatacagctt cactagcatc gattccgatt acgtcttcga
    39661 tttcttgacg gacacgttcg ggatctgctg cgggtaggtc gattttattg atgactggca
    39721 ggatctccaa atcattgtct aacgctaaat aaacattggc caatgtttgt gcttcgattc
    39781 cttgtgctgc atcgaccact aaaacggcac cctcacaggc agcaaggctt cgagagactt
    39841 cataggtgaa gtcgacgtgc cctggggtgt caatcaagtg aaagatatat gtttctccat
    39901 ttttcgctgt gtaattgagt tctacagcat ttaatttaat cgtgattcca cgttcacgtt
    39961 ccaaatccat cgagtctaac agctgatctt gcatttcgcg agacgtcaca gtgtgcgtca
    40021 tttctaaaat acgatcggcc aatgtagatt tcccatggtc gatatgagcg atgatcgaaa
    40081 aattacgaat ctgctcttgg cgttctttca ttttctttat atccatagcg tctcctcttt
    40141 tcatataatc agcactttcc attataccaa cgaaaagcag taatttaaag agtttttaat
    40201 tagtcagcta tagaagtttt ttttgtagaa ttttgctata ctgttatcaa gctaataaat
    40261 ggagatgaaa aaatggatca aaaagatttt agagaaaatc ttgaattaaa accggtcact
    40321 caagaacata tcgatcaatt caatgaattg ctttcctatg tgttccaagt gactgaagca
    40381 gacatcgagg aaagcgggtt tgagaataaa cgagctttta tccgttccaa aaaaccgatt
    40441 ttggaagtat cgaaagtgtt cggatggttc cacgaaaata aactgatctc tcaaatcgct
    40501 atctatcctt gtgaagtcaa tattcacggt gcacgttata aaatgggtgg tgtgactgga
    40561 gttggaactt atccagaata tgctaaccat ggattgatgc aagatctaat tatcgttgca
    40621 ttggataata tgcgcaagaa taagcaatgg atctcttatt tgtatcctta cagtatcccc
    40681 tactatcggc gtaaaggatg ggaaatcatg tctgataaac tttcctttaa aatcagagat
    40741 acacagctac ctaaacaaat cccagtaagt ggtatggttg agcgattacc agttgatcat
    40801 ccagacgtat tttccgttta tgacaaattt gcccaacaaa accatggtgc tttattccgc
    40861 agtgattttc attgggaaga gtattggcgt ttcgaaaatg aagatgagcg cacagccgct
    40921 gtctactacg atagcaacca tgaaccaaga ggtgttctgt tctactgggt agctgaagaa
    40981 atatttcacg taaaagaaat gttctatctt gatcaagaag ctcgaaatgg cttatggaac
    41041 tttatttccg cacatttttc catgatctac tgggtacatg gagatattta taaaaatgag
    41101 cctttagcat ttttgattga agatagtcag atcaaagagc agatcgaacc atattttatg
    41161 gctcggatcg ttgatgtaaa agaattcctt caacggtttc cgtttgttgg aacagctgat
    41221 gcttttcatt tcatcattga agatcctgtc gctccttgga ataatggtgt cttcgcttta
    41281 acatgggatg aacagggaca agtccgtgtc ttaaatgaac ctataggaaa atccgttcga
    41341 ctggatatcc aaacattgac ttgcttgatg atgaattatc gccgtgcttc ttatttggca
    41401 agaatcgaac ggttagaaac agatgaagaa acactgaagt cactagagcg tatcattcca
    41461 aacatggaag cttactttag cgattatttt tgataaaaag gatgatgttt agatgaaaat
    41521 ttattttgcc gcaccaatgt ttgctaaaag tgatttgtta tataaccaac agttagttaa
    41581 agaaatcaga gagctctctt ctgagctttc gatctatctt cctcaagaaa atgaagcaat
    41641 caatgacaaa actgcttatg cagacagtcg aatgattgct cttgctgaca cagaaaaagt
    41701 gttggctagt gatttaatga ttgctttact agatgggctg acgatcgatg ccggggtagc
    41761 atcggaaatc ggtgtggctt atgcgaaagg catcccagtg atcggcttat atactgatac
    41821 tcgacagcaa ggcggaaccc acccgaaaaa aatcgctgca ctacaagaaa cagctgaaaa
    41881 tcaatttcac tacctgaact tatatacaat aggtttgatc aaattgaacg gaaaagtggt
    41941 ttcttcagaa attgagttgc tttcagaagt aaaaagattt ttagatggag ggactttcag
    42001 tgattaaaga aatcaaaaag gtgcaaatag ctttacttgc ttttggtgta ttcgttgtct
    42061 gctataattt ttatgaattt atcacacaaa aatattcgac ttctcaagga atcacattta
    42121 tcgtggaatc tttattaggg attgcattga ttttcatgcc acaagtcatt ttgaaagttt
    42181 tcaaacttaa aataccagca gcaatcgttt tgttttactg gtttttcttg ttcatctctg
    42241 tctttttagg cacagggatg catttgatca gtatcatctc tttttgggac aaaatcttac
    42301 atgcggtgag tccaatggtc ctgacagctc ttggctatgg attgattggt tacttgatga
    42361 aagatgctga gatatcaaaa accagtcctt ggttgttcct cttattcggc tttgcgtttg
    42421 ctggactttg cggcgtgttt tgggagttct gggaattctt atgcgaccag ttcttaggca
    42481 tgaatcttca acgttttgct gcttctgatg gcacactgtt tgtcggacga gcagcattga
    42541 tggatacgat gggcgacttg ctgacaaata cgataggtgc tgccttaatg ggattgtttg
    42601 catggtctca aagtaaaaaa gatgagcgtt actttgaaag ttataaatta gaaaaagtga
    42661 aaaataccta ataaaagagg ttgtgacaga agcgggcagc ttcaagaaat ttcggcttat
    42721 ttttcgaaga aactacttct ggaacactgt ttatttgaaa aaaggaggtc tgacactagt
    42781 tgtgtcagac cccttttttc ttttatagtc tcaatggaag attagacgat ttcttctagc
    42841 tcttctgttt tgaaatgaag ttgtccatca agtaaagtaa tcgttacttt tgatttaggc
    42901 ataacatgtc ctgcaacgat ttctttagct agtggtgttt ctacttcctt agtgataaat
    42961 cgtttcaatg gtcttgcacc atatgctggt tcataagcat tttcagcaat ccacgttttg
    43021 gcttcatcac tgattgtcag caggatttct tgatgttcca gacgttgtgc caattgcgcc
    43081 accattttgt caacgattcc tttcacgttg tctaggctca atggtgtaaa taaaatcgtg
    43141 tcgtcgattc ggttcaagaa ttctggtttg aagtttccac gtaatagcgt gttgacttgt
    43201 tcagccactg cttctggaat cgttccatca gcagtcacgc cttccagcag taactgtgaa
    43261 ccgatattgc tggtcatgat cagaaccgta tttttgaaat ctactactcg cccttttgaa
    43321 tcagtcaagc gtccgtcatc taggacttgt aacaagatat tgaagacatc gggatgcgct
    43381 ttttcgattt catccaacaa gacgattgta taaggatttc gtctgacagc ttccgttaat
    43441 tgaccacctt cttcgtaacc tacatagcct ggaggagctc cgactagacg agacacagca
    43501 tgtttttcca tatattcact catatcgatc cgtaccatat gatcttctga gtcaaacaag
    43561 ttctcagcta acgctttcgc taattcggtt tttccgacac cagttggtcc taggaaaagg
    43621 aaagaaccta gaggacgatt tgggtcttgc aatccagccc gtgaacgaat taccgcgtca
    43681 ctgaccgcat caactgcttc atcttgacca atcactcgtt tatgaagtgt ttcattcaat
    43741 ttaattagtt tttctcgttc accttctaca agtttcgtta cggggatacc cgttaatctg
    43801 ccaacgactt gagcaatctc attttcggta acggactctt gaaccatctt aatctcgctg
    43861 tcttttgctt tagcttctaa ttccttcaat tctttttcta attgaggtat cgtaccatga
    43921 cgcaatacag cagcgcgttc taaatcatag ttattttctg catcttctaa ttcgtgtttt
    43981 gctttatcga tttcagcacg ttttgctgaa acagaattga cttcttcttt ttctgtttcc
    44041 cactgcatct tcatcgcatt tgcttcttca cgaagttcag ctaattcttc ttgcaaattt
    44101 ttcaagcgtt ttttacttgc atcatctgat tcttttttca gtgcagcttc ttcgatttcc
    44161 aactgcatca aacgtctagt aacttgatct aattccgttg gcatagagtt catttctacc
    44221 cgaatcgttg cactggcttc atcgatcaaa tcgattgctt tgtccggtaa gaaccgatca
    44281 gtaatataac ggtcagataa agtagctgct gctactaatg cgttgtcatg gatgttaaca
    44341 ccatggtgga tctcaaaacg ttcttttaat ccacgcagaa tactgatcgt atcttccact
    44401 gttggttctt tgactaatac cttttgaaag cgacgttcca acgctttgtc tttttccata
    44461 tattgacggt actcatctaa agttgtggca ccgatcaaat gtaattcacc gcgagcaagc
    44521 attggtttca acagatttcc ggcatccata cttccttctg tttttcctgc ccctacgata
    44581 ttgtggattt catcgatgaa caagaggata cgtccatcac tttttttgac ttctttcaag
    44641 actgctttta gtctttcttc aaattcacca cggaattttg ctccagcgat caatgcaccc
    44701 atatctaatg aaaaaatcgt tttatctttt aaattttcag gcacatcttt gcgtacgata
    44761 cgttgagcaa gcccttcaac gattgccgtt ttccctacac cgggttctcc tatcagaaca
    44821 ggattatttt ttgtttttcg tgaaagaata cggatgacat cacggatttc ttcatcacga
    44881 ccgatgattg gatccatttt tccgcttttg acttgctgta ctaaatcaac gccgtatttt
    44941 tctaatgctt tgtattgttc ttcttggttt tgtgaggtca ctctttctcc tcctctcatc
    45001 tcttcgatgt ttttacgcaa ttctttttca gataatccgt ttttattcaa ataaacagtt
    45061 aacggataat tttttaattt catcaacgct aaaataacga cttccgttga aagaaactcg
    45121 tcgccgaagc tttcacgtat ttggtctgct tcattcaata atcgaaagaa attctggctg
    45181 aggttttgtc catattggac gtttccacca gaaacaactg gatactcatc cagtagacga
    45241 tcaatttcat gttcaaaaga ttcgacatcc aatccggcat ccgtatagaa atttcgacca
    45301 aaatgattag attgtaaaaa gattttccat acatgggcaa tgtcgatatc ttgatgtttt
    45361 cgagtgaccg caatctgttg agcttcagca atcgcttctt gaagcgtcgt agtcattttc
    45421 tcaatattca tacaggtata ccctcctaat taaaggtaag atcacttatt tctttgatct
    45481 ttacaaaaac tattatatcg ctttggtcaa ttttggtcaa aatatacaca tagttttttg
    45541 actttttttc tcgacttata taaatcttaa aaaaacaaaa ttgattgtat gtatataaaa
    45601 aaagagccaa acaaacgtaa aattatctta tccataacgt ttttctttga tttgataaaa
    45661 agggtagatc ttataaaaga cctacccttg attttcttta ttctcttttt ttacttctat
    45721 tatttcttct ttgatcactc ttcgccgttc agcaatcaca tacacaaatc catagagaaa
    45781 tggcaagata aaggaactga aacgatacag taaaagcgaa gaaactgcgt caactgttcc
    45841 aacaactggt ctgaataata acaaatagac aaattcaaag gaaccaatac cagcaggcgt
    45901 aggaataacc cctgaaagca ctactgcaaa gctgataaac gaaatggtca gtagaaaatc
    45961 tattttagga tggttttcaa tcagaatcaa ataaggaagt acataccaaa atacaagttt
    46021 taacatattc catagataaa tccgcaatag cgcagtcctg tcttggataa tggtttggac
    46081 cgtttccctt aaagagtaga tctgctgatt gcatgtatcc acccatttcc gcaaacgctc
    46141 acttttaaat aacttattcg ataagctgac aaaaaatatt tgaacattca agctgacgga
    46201 catcgccaat aaaaaggcaa caatcacgat cgtcaaaagg ataccagcga tgataaacca
    46261 gatcattgat ggaccattag aataaaaaag agagaattgg atgaccaagc cagctaatgc
    46321 ataagtgatc actgccagtt tgtacataat catatggagt gctgtcaccc ctgctccctg
    46381 ggatagcttc attccttttt tgttataaaa ataaatctcc gagatcagcg ttcctgtacc
    46441 aaacgaaacg attcggtaaa acgcaatata gctagaggtc aagaacccat ctttcgttgt
    46501 aaaattcggc gcgaaaggtt cagcaatttc tttgattgag cgcccttcag cgatttggta
    46561 aactgtccct aatataacag ccgctgccaa aacaacaaca ctggtagaca gcaattcggc
    46621 aaagatatct gcaaatgatt gattgattaa ataataaata atggcaaaaa tcacaatcag
    46681 caaaagcaga ttcagaatga ttttagtttt cgttccttta gacgacatct cctgctcctt
    46741 aatggaaaaa ataaatgaga atcaaatcaa caagtacacc tgcagcgaat cctatagtaa
    46801 acttcttttt ccgagtttta tgatggaaaa cttttcgaga gatcaatcct cccaaaccac
    46861 cgcctaacag gctgacaaat atcaaattat tctcaggaac acgccagccg ctagttctag
    46921 cctgatgttt atcatacccc atcagacaaa ataagtaaaa attcacaatg aaaaggtaaa
    46981 accacaaagg attgtgtaac aatacatcca ttactcttct tccaactttc tgttaactac
    47041 tatttctaag ctttttcttc tttctttggt gaataaactg ttaatccttt tgatacaaca
    47101 gataattcaa ctggaagatc atctgtcgtg tctccatccg ttcgagtgcc cacagatttt
    47161 tcctgcgctt ggattttcat gcgtttggct gtgaaataag taatgccggg gatcgtatag
    47221 aatttgcctc tcatgattct aggcaaataa aaaataaatc ggaaaatatc taaggaaggt
    47281 acgatcgtta catgaaattt tccatcatct agggtcgctg agtcgtcaaa atttgtaaaa
    47341 ccgcccacgg agttagacat cgtgactgtc aacagttggg attttccttt ccaatgctcc
    47401 tcgtctgttt ctaaatccaa atgatatttt ttcttcttca gcaataactt aaaaaacttc
    47461 ttgataaaga tccacgagcc gtaacgctgt ttttcttctt gactgatcca aactgctgta
    47521 tctgctaaga ttccgattgt cagtgtagag ataatgactt catcattgac ttgaccatag
    47581 tctattttcc gtacattgcc ttccaggatc acgtcagcag cttcttcttt tttgagggga
    47641 atctcaagaa cacgtgcaag gttgttgaca gttccacctg gaagtaatcc gacatggtat
    47701 tgagataatg ttttttggaa cgcttggacg atatgatgaa tcgtgccgtc tccacctata
    47761 attactaaag tatcagcttc tatggcttct gctttcttga ctaattccgc atcatcaatc
    47821 gatgggccag tttcagctag ttctacatat aattctggct gcttttcttt tacataatct
    47881 tgaaaccagc gtgctaattt ctcaccctca tctttccctg aacttttgtt ataaaaaact
    47941 agcagctttt ccattcttta cctcctattt actcttcaaa aaagagggcg ggacaaccaa
    48001 ttccattgtc ctgcccttta gccttagaca gatgacattc catcattggg acgaacgcct
    48061 tgtcataagc tgttcttttt cgattttaac tctttgtgtt caattctgca atttttacaa
    48121 tcacgtctgt tgctttttcc attacttgta aagaaacaaa ttcgaatcgt ccgtgcatat
    48181 tttctcctcc ggcaaataga tttggcgtcg gaatacccat gtaagagatt tttgaaccat
    48241 ctgttcctcc acgaactggt tcgatcactg gagagatacc aagctcgatc attgcttgtt
    48301 tcgctaattc cacgatgctc atatcttttt caatgatttc tttcatgttg taatattgat
    48361 catacatatc tactttgatt cgttcttgat caaatcgctg attcaactct tcttggatat
    48421 gtgtgatttg tgctttgcgt gcttcgaatt tttcacgatc atgatcgcga atgatataac
    48481 tcatagaagc ttcttcagga ttcccatcca atgccatcaa atggaagaaa ccttcgtatc
    48541 cttccgtttt ttctggaact tcatcggctg gaagctgatt atgaaaatcg attgctaact
    48601 gtagagcatt gatcattgta tcttttgccg tccctggatg tacatttttc ccttggatcg
    48661 taatatttgc ttgagcagca ctaaacgttt catactgcaa ctcacctaaa ggaccaccat
    48721 cgactgtata agcaaaatct acatcgaatt gctcaacatc gaatttatcc gctccgacac
    48781 cgatttcttc atcaggacca aaagccactt tgatggtacc gtgagggata gaaggattat
    48841 tgatcaagat ctccattgca gtcatgattt ccgcaatccc tgatttgtca tctgctccca
    48901 gtaatgtact gccatctgtt gtgatcaatg tgtggccttc ataatttttc aaatttggaa
    48961 aatcttttgt attcaatgta tagcgttctt ccgcatctag tacgatcgta gactcgccat
    49021 catagttttc aatgatttgt ggattgactc ctactgcatt aaaatctgct gtatccatgt
    49081 gggaaataaa tccaatggaa cgcacttcat gatcaacatt gcttggtaat gttcccataa
    49141 cgaatccgtt atcttcatta tagaaaacat cagctaagcc taactcttct aattcttttt
    49201 tcaattcttg cgcaaaagca acttgtgtct gagtcgatgg agtcgttttg cttgttgcat
    49261 cggagcgtgt ttctgttttg acatatcgta aaaaacgtgg caaaagattt tcgtacatag
    49321 tattctctcc ttttaattaa attgaaatgg gtttgtattt gtttcagaaa cgaaaaagtt
    49381 aatatcccaa ttttcttctt gtttccaaga ttcaaatttc tcgataaatc gttgcttgca
    49441 taacgattca atataatgac cgggatcaat tgcaatcaac ccagcgcttt gcatatcatg
    49501 agccgtatga taatagatat ctcccgtgat atagacatct gctctttggg cgattgcttg
    49561 cggataaaat ttttcaccgc ttccaccgca aatcgcaatg cgcttcacag aggattttgc
    49621 attttttggc tggactattc tcagtccatc tagttggaac gcttctttta cttgttctac
    49681 aaatgcctct atagaaattt cttgcggcaa ttcacctact cgtcctaacc caaacatttc
    49741 gactggttca tctatagcga aaagatcata agcaggttcc tcataaggat gagctgaccg
    49801 catggcttga atcacttgtt tttcgatagt ttccggcaaa ataacctcaa cttttgcctc
    49861 ttgaacttgt tctgtcttcc ctactttccc aatcgctggt tgtgcaccag cttccggagt
    49921 aaatcgaccg tgtccaatcg aggtaaaact tgtaccggta taatcacctt gtgtaccagc
    49981 accagctgca gctaatactt cacgcatttt ctgtgcatga tccacaggta cataaacggc
    50041 cagtttttta taatgaatct catgagtctt tactaaataa ctctccactt caataccgag
    50101 aagttcacaa aaccagtcat tcagtccatc ccaaataata tccatgttcg tgtgtgctgc
    50161 atagacggca atatcatgtt tcaacaaatc tgcatacatt ttttcttgtg gctgatcagt
    50221 aaccagccgt tttacaggac gaaagattgg aggatgttta gcaatcagca aatcgatttt
    50281 tttcttgatt gcttcttcga ccacttctgg acgaacgtct aatgtcatca ttactcgttg
    50341 gattggctta tccaatgttc cgatatgcag tccgactggg tctccttctt cagctagcca
    50401 ctgaggacaa tagctttcaa acttttggat gaaagtgcgt ccgctgattg tcatggcttt
    50461 aaaacctcct caatcatttg gatttcctgc tcgatttgtt tttgacgtgc ctcttgatta
    50521 gctgcttgtt tgagctgttc acggatagct tttctttgtt gaagctctct tgtccatttt
    50581 gatttgaaga tctcactttt ctcttcaagc agaaatggcc cgaacatcag ctccatttca
    50641 ttgtaagtaa ctggtttttg ttctttttcg gctacaatga tttcatatat ttttttattt
    50701 tcttcaagta ttttttctga ttggatttta tactgatttt cttgcagcca agatcgtaat
    50761 gtacgctctc cgatgtttgg ctgaaggatc aaacgttctt gtccgcttaa gcgttgattc
    50821 aacttgccag cttctaggat atctcggatc agtgaacctc ccatacccgc aatcgtgaca
    50881 gctgtaatac catcttgtgg ctggatagca tctagaccat ttgcaaggcg tacggtgata
    50941 cggtcttcta atccatcttt tttgacttgc ttacgtgctg attcataagg accttgaacg
    51001 acttcaccag caactgcata ttcgattttt cctcttaata tcaatgcaac gggtaagtaa
    51061 gcgtgatctg atccaatgtc tgctaaacga gcggattcag ggacaaagtc acccactgcg
    51121 gctaagcgct gagataaatc taaatggttc atagcttcac tccttctaga taattatagc
    51181 attttccaaa taaaataagg agactaggaa taaaaaaatt cccatatctc cttaaaaaat
    51241 ataccttttc gttctataaa acaacatttt cttatttttg aaaaaatgtt attggttatt
    51301 tgttcaatga aacatcaata atcgaatctc caggaacttg cggtgggata gacatcgtca
    51361 tgatcggcat ctcaactaat gtaaattgga ctttgtcacc gattttcaat tcatttatgt
    51421 ccacgcttat tttttcagca gtagcattta agatcactcc gtcattgctg aatgacgttc
    51481 ccatattcgc tggatcttct ttggccatga catcgacgag tttcaactga agcgtttctt
    51541 cttctgcttc tacttgagtg atactttcaa tcgttccgac aaatatgctt tgtctctccg
    51601 ttttcgtact gcttgttttt actgtttgac ccgcatcaat cgaatcaaca gaacctgtgt
    51661 tgctatctgc gctaccgcag cctgctaaaa gaaaaaatag accaactaca gatatactag
    51721 aaaaaatagc cctcataaaa aatcctccgt ttaagtttct gcattacttg ttgcggtgat
    51781 tgtctccggt catttctgtc catataatga ttcgctgacc tgcttttact actaggtcaa
    51841 atgtcagttg gacttgtcaa ctgttcaacc attgcgtcgg ttgcgaccag tcatttcgat
    51901 ttcttttgtc aaataacgta tgcgttccat tatccgtttc gcttttagcg gctcttcatc
    51961 tccacgttga gtgacggaca aatgctgttc caattcatcc attgtaaaat tcgatgagaa
    52021 gaaggttggt aactgttcct gcatccgata ttgaaggata acaccgaata cttcgtctcg
    52081 tatccaacta ctcatcgcat ctgcaccaat gtcatcgatc atcaaaatag gtgaacgttt
    52141 cactgcatct aacttttctg ccacttgatc ttttccgatt gcctgtttca tctcaacggc
    52201 aaatgtcgga aaatggacta gcgtcgtggt gaatccagca atcgctaatt ctctcgctgt
    52261 tgctcctaat aaatatgttt ttccaatacc aaaacttcct actagataca gtcctttatg
    52321 ataccctttt ggatcagcag tatatttctc tacaaaatct agggcttcta agctcgcata
    52381 tcctcgtcca tctgtacgtt caaagttttc aaaagaagcc gattgaatat cttttggcat
    52441 atccattgct tttactcggc ttctgatttc ttcttgtctt tgccgtgcta acaatgcttc
    52501 cgttggtaca taagtgacat ccacataatg aaaattcaac gtcagcttcg gctcatagcc
    52561 gggagcgatc atcgttggat cgtttttttg atatttacgc ttttcttgca cgaattcata
    52621 caatttagcg taactttttt caatatccgc ttgtgtcaat tcttcttggt gtgcgcttag
    52681 aaaagcttga acatccgcat catttaagac ttcagcgatc atttcagcat acttttcttg
    52741 ataattgcgt ttgctgatga tcctcttcaa ttctttgcct acgtcttcca ctagatatca
    52801 ccctcctttt ttgccaggta ttctttaaaa cggcggtcaa tctctgcttt tttctcgctg
    52861 ctgatctgtt tttcatcttt tggctggttg acccaatcag gaagcttttc ccgtcgaaca
    52921 tttcgcttgc cagtttgata atttgtttgc ttcttttgtt ttgattgttt tgcttgatta
    52981 cttatttgcc gaatgtgctg gatcgcttct tctgctgtgg cgattttctt ttgtgcccat
    53041 tcatttgcca ctgtatttac ataactggca tttaagctag cattattctt gatcactagt
    53101 acataattca gcaaaacatt gatcacgcta ctggaaagac ctgattgaga aacaagatct
    53161 tgcagtaacc agttttcttg tttagaaaca tatccgcctt tttctgactt gattgcttcc
    53221 agatatttca tcggtggaat gctctgtgct tcttttatca gctgaagcgc tgcgtttgtc
    53281 aaatgttcgt ttgacgaggg ttcattactg ttttcagaaa ccgcaactgt ttcttttgtt
    53341 tgcttcaccg gacgtctctg cattgccaaa atggcttttt gcagttcttt ttcagatact
    53401 ttttgttcac taaagtcata agattgactg atcagttcgc caagtgtcaa ttcatcgaaa
    53461 ccgtaaagct gatgatacat gtcgacttgt ttgatgattg gatcatcaag acttgcaata
    53521 tgtttttttg ccagccaatc attcaaaaac tgccaatcga atgtcgaatc tgcttcaagt
    53581 aatgctactg attcagattc ttcaaaagat ttattcagcg attcgatgtt ttcttgatta
    53641 gcagcgtaca ctgcttcatt gaagcgataa acatctaaaa atttttttgt gattttttga
    53701 tatccctctg ctgtatgcct tttaggttca aagaattggg taagcttctg gaatcgtcgt
    53761 tcaccaactt tttccagaag aagaaaagcc agaacagagt ctttgaaaaa tgctttagga
    53821 atgagtggtt ctaacagctc ataaataaaa cgaggtccca gatcactatc ttctttaaaa
    53881 taaacatcca gtaagccgat tccttctagc ttttttcttg catcataaaa ttgcgggata
    53941 ccgcagccta gactactaag cagatctgca tgcatccctt caggaccttt gccagattct
    54001 tgagagattt ctgataacag ggtgaaatag atactcaagg cttctccgcc gattagtggc
    54061 tgataaagat acagcaaggc gttcttgctg tcttctctca gcggagccgc ttttcttcct
    54121 tggtaaatat tttttggttg aagctctttc caagcatttt ccaaggaaat gcctcctttt
    54181 tgtttcttaa ttgttttctt tattattctc tttattattt tcttttgctt tatccacgat
    54241 atcttgcaac tcttttaaga aaacagacat atctttgaac tggcgataaa cacttgcaaa
    54301 acgaatataa gcgatttcgt ctaaatcaac taaatcttcc atcacatatt caccaattag
    54361 attcgtcgat acttcgtttt ctccgagact gcgtacgcgg ttttcgacat ggttgacgat
    54421 ttgttccatt tgttccatag ctacaggtct tttttctgct gaacggatga gtcctcttaa
    54481 aattttatcg cgattgaact cttcgcgttc cccgtttttc ttgattacta ataacggagc
    54541 agcttcaatt cgttcaaatg tagtgaatcg gaacgaacaa ttctcacatt cgcgacggcg
    54601 acggatcgca cgtccatcat ctgcttgacg gctgtcgatt actcgtgaat tattatgttg
    54661 acatctggga catctcattt tgtctcacct cttgcatcgc attttatata aaggatgtgt
    54721 ctttctttac aactagttgt attataacac gaaacaaatc acaaacgcga ctgtcctacc
    54781 caaaaaacac ggatataaga acaatttttt ctactttcat gcgtaattgt gtcccctgtc
    54841 cttactaaat ttcaattttc caatactgat caccttgatt actgagaaat aacttacaca
    54901 aaagctgatt tagtcatcta gcacaaaaaa cttgaagcag atgaacacct tctcatctgc
    54961 ttcaagtcac atctcgattt tttactattt tataacttct cttcgattcc tgtatagtgt
    55021 ttcattcgct gttcctcgat tttttgctca tcgggaatgt ggtcactttc tgggagcggt
    55081 gttttactac gatcaggtgt cggatttttt cgttcttgag tcaaatcttg ccgcttcgct
    55141 tcttcttctg cctgctggtc ttctatttca tcgattcttg cttggtactg cttttctttt
    55201 tcttctgctg tttctgattg cgtacgacct tcatcgatta gattttcttt attgagcatc
    55261 tcgccgattt tttcttttgc gttacctacg actttatcct tttgattttt taatgatccc
    55321 atcgctatcc ctcactttct atatactcag gatagcaaaa ttgacacaga tactcaaaga
    55381 aagcgattag caaaaagcca attttcgatt tgtcccacaa gtatttcttt tgttccattg
    55441 ttgtcgaaca aaatatccgc acgctgcttt ttttcttcga ttggaagttg actactaatt
    55501 ctctgctgcg cttgttctag cgtcagttga ttacgtttca tcaaacgctg aagctgagtt
    55561 tctggcgtag tataaacgac agctactgca tccatatagt ggtcataatg accttcgtag
    55621 agcaatggga tatctacaat tactaaagga tgattggaac ttagagaggc gatttgatct
    55681 tttatcgctt ttcggataaa cggatctaat agctgatcaa gtttttgccg tttttccttt
    55741 gatggaaaaa caatcatccc aagtttccct cgatctagtt gcccatcagg ctgcaatacc
    55801 tcttggccaa acactgatac aattttcctc agagcaagcg ttccaggctc aacagtttct
    55861 ctggcaatca catcgccatc gatcaaagga aatccatgag actgaaagac tttggctgcc
    55921 gtacttttac cggtagctat tccacccgtc aaacctaaaa caaatcctac tttgcgattt
    55981 ttagcctttg acaattcgga caatagtgcg tccccctttg tgccactttt gttttcacga
    56041 tcggcgttcc acaacgtata catggtttgc cagtttgctg atagacatgc agtgctactt
    56101 gaaatccgcc tgattctcct aatgcattca aataactgcg aatcgtggta cctccggctt
    56161 ctattgcacg atccaaaaca tcaatgatcg atagacgtaa ttgttctacc tctttggggc
    56221 gcagtgtgtt cgccggttgt tctggatgga tcttcgcttc ccataatgct tcatctacat
    56281 aaatattacc tagaccagtc actagacgtt ggtctagcag caatggcttg attgctttgt
    56341 gggacttttt cagtccattt gcgaaatctg ctaataagaa gctatctggc aaaggctcag
    56401 gtcccaattt catgattcct cggtaagttg cacttgctcc tttttcgacg attgtcatac
    56461 gaccaaattt tcgtacatcg ttgtagcgaa gttggcttcc atcctcaaaa aagaaaagta
    56521 catgcgtatg tttatcgatt ggtgtatttt ctttcgtaaa ttgatatttt ccttccattc
    56581 gcaagtgtga gatcagttca caatgatcga gatgaaaaat taaaaacttc cctctacgtc
    56641 caatggattg gatggtttcg ccaacaagag aagcctcaaa gatgggtgtc tctggttgct
    56701 cgatgatctt gggccacaag acctgaactt tttgaatcgt ttttcctact actaaccgtt
    56761 ccaatccttt acgaacggtt tctacttctg gtaattctgg cattttttct tttcaccttc
    56821 attatattgc tctgtcttaa acaatgttta ttttgcttcg taccacgttt ttccccaact
    56881 gctgtcagtg atcagtggta catgaagaga aacagcttgt tccataactt ccttcaccaa
    56941 tttatctaat gattcaagtt ctttttccgg tacctcgaag acaagttcat catgaacttg
    57001 taacagcatc gtagcttgaa gacctgtttc ttttaatcgt ttatccaatt cgatcatcgc
    57061 gattttcaaa atatcagcag cacttccttg gattggtgta ttgatagctg ttcgttccgc
    57121 aaaagaacgg atattgtaat ttcttgaatt gatgtctggc agatatcgac ggcggtgata
    57181 cagcgtttcg acgtagcctt ggtcttttgc ttcgcgtacg attctttcca tatattcttt
    57241 gacacctggg tatttttcaa agtacgtatc gatgtattgc tgtgctgctt ttcggctgat
    57301 tcctagattt tgtgaaagtc cgtaatcaga gatgccatac acgataccaa aattcactgc
    57361 ttttgcctgc ctacgcatat ttggtgtgac atcctctgcc ttttcgattc caaatacacg
    57421 catcgctgtg ctggcatgga tatcttgacc ttctaggaag gcagctttca aatgttcatc
    57481 atttgagata tgcgcaagta cgcgtaactc gatttgtgaa tagtcagaag aataaatcag
    57541 ccagtctttt tctctaggaa caaatgcctg acgtatcttt ctcccttcat ctaatcgaat
    57601 cgggatgttc tgcaaattag gatcaacaga gcttaatcgt cctgtttggg tcaatgtctg
    57661 gacataacgg gtatgcactt ttccatctga ttggatcact ttcagcagtc cctcgacata
    57721 ggtagattga atttttgcaa tttgacgata ggtgaggata tcctctacga ttggtgcttg
    57781 ttcacgaagc tgttccagta catctacggc tgtggaatat ccagtttttg tttttttgat
    57841 aacgggtaat cccatttttt caaataagat cactcctaat tgctttggtg aattcaaatt
    57901 gaattcttcg ccggcttctt cgtagatttt ttgttcgatc tctcttaagc gagcagagaa
    57961 ctcgcccttc atttcttgta agcgagtcgc atctactttg atcccgctta tttccatctc
    58021 tgccaaaatg atagacaatg gcagttccat tttccggaaa agatcttctt ggtttttttc
    58081 tgccagttct tggctcaatt ttggtgtcaa cgcattgatt gcagctactt ttcgcgctaa
    58141 atgagcaaaa aagagttcct cttcttctgg taaacctttt ttcgcccctt tgccgtatac
    58201 agcttcatct gattggatat cgttgtatcc gtaatgagca gctattcctt cgatatctgt
    58261 gcttttttca ttcgtatcga gaaggtatgc acctagcaag acatcaaaat cgattccttt
    58321 cgtttttcca gtatagcggt ttaaagcaac ataagttcgt ttcgcatcat atactttttt
    58381 cagccgagtc ggatcagtga tccaagaatg gaacgctcgg ttttcgaata cagatagatc
    58441 gttcgtgaca taaattttct tttctgtccc ccacgctact ccgacgattt cctctgtatg
    58501 ataattgtcg cccatcattt ccacgtacaa cgccatatcc gtagtaaaca tttcctcttt
    58561 gaattcatga acgacttcaa acaaaatatc atccattttt acttcttctt ctacgatatt
    58621 caatttagaa aggaactgat tgaaatccat ttctttataa aacggaacga gtttatcgag
    58681 atttttccct tcatacttca atgagtcgat agagacatcc acaggcgctg aagtattgat
    58741 ggtcgccaat tttttcgata agaaagcctg ctctttgtca tttatcagat tttctttcat
    58801 tttgctttgc ttcatttcat cgatatgttc ataaattcct tcgactgagc catattgttt
    58861 caatagcttg atagctgttt tttcaccgat tttagtcaca ccggggatat tgtcagaggc
    58921 atctccggct agtcccttca tgtcaataat ctgttttggc gtcaacccat catatttttc
    58981 cgctacatgt tctggtgtat agctttcgat atcgctgaca ccttttacag tgatatccac
    59041 ttttacttct ttactagcta attgagtcaa atcccgatca cctgaaagca cgacgacatc
    59101 aaattgatct ttgtctactt tttctgccaa agtaccgata atatcatctg cttcataatt
    59161 gggcaattcg taatactgta cccctagtcc tgtcaacaaa tcacgtatat atggcatttg
    59221 ttctttgaat tcgccaggtg ttttggatct tccacctttg tactccgcat acatttctgt
    59281 ccgaaaagtc gtttttcctg catcgaacgc aaccagaaca tgagtcggtt gctctttttg
    59341 cataacattt tcaaacatcg tattgaatgc atagattgca tttgtatgaa gaccgtttct
    59401 atttttgaaa cgttcaagag aattgtgaag cgcaaagaat gcgcgaaaag ccacactgtt
    59461 cccatcaacg agtaataatt tattttttgt catcttctta actccttact gtaaagttct
    59521 tattcattct aacaaagaat cctgcggaat gcgaaaagaa aaagcgggac cataccaaat
    59581 aattcggtat agccccaact gatgaatttt tttctttttt agttgttccg tccaaagatt
    59641 ctcagaaacg ccaagaacaa gttgataaag tccaaataca gcttcaatgc catgaataca
    59701 gcaattccac tatgtgctgt tccgtttgtc tggacataga tattacggat gctttggtta
    59761 tcataagctg taatccctgc aaagatgacg actaacagta gggagatgaa cagctcaact
    59821 acgctacttc tcaaaatgaa gatgttcaag actagtgcaa tgatcactcc gattaaagct
    59881 gcctgtcctg ctcttccaac cccgctaaga tctctttttg ttgttactcc gacaacagac
    59941 atccccatga acatcaaagt agctgtcaag aaagcttgcg ttactgttcc aatatcgtag
    60001 tatgcaagag taaccgctaa tattatgcca ttcaaaagag agtaggcaat aaatccaccg
    60061 attgctaagc tcggattctt ttgtgctttt acgcctagaa ccattactaa aatcagttca
    60121 acgatccaca gacccacaaa gcctagtgga aaattattga taaaagttgc taattgcaaa
    60181 ggaaataccc aaagagccaa gtaagaagtg actgcactaa gggcaagtcc catacctaaa
    60241 aatccataaa cttttgcata aaaacgattg atacctgaca ttgatgtact tggattattc
    60301 attcaattca ccttcacttt cgattgctat ttccaattca ggaacttgtg gcggttggac
    60361 cataacgaca gcatccaaca cacgatcttc gttcgtattc tccgcttcta cagaaatcgt
    60421 caccacatcc ttcatcttat ctacttttat gacctcaaac tgaaaagtca gtgtttcata
    60481 atggaaaacc ggttcaataa aattgacaga aaaattgaca acatgtgatc ctggtccagg
    60541 aagatgcttt gaaattgcac ttgtgatgat ccccatcagc atcactgatg gaacgattgg
    60601 ctgttgatat tctgtttttt gtgcaaagtc atgttggata tacaaaggat ttgcatcatt
    60661 cgtcaatccc aaatacagca aaagctggtt atcttcaata gattctgtta aggataacga
    60721 gtcgccttcc tcgatttcat ttattgtttt tcctagtttt ctcggcttac ctatgttcaa
    60781 gatagaaacc ctccagttta tttttaatca tacattattg taccaaaagt agcgtaaaag
    60841 gcaagttctg ctcccttgat ttaacagatt cctatagttt acagaggtcg tgaaaaagct
    60901 gtcctgcatc aaataataag aacagccaag aaaaaacagc ttctcatgtt tttgatttga
    60961 ttgggcttat taccgcagat gcaagctttt gaacaccgtt tatcataagt tgcaaaaaag
    61021 ggggcttggc aagatttttg ccactccccc tctttctatt tttataagga cactgcagta
    61081 attgtattac agtacatttt tcgtcgtgct gcttaaaagt ttttcatacg cttgttcaaa
    61141 tttttgaaca tctccagcac ccatgaagat tactactgca tcatgataat ctaacaatgg
    61201 agatacatta ttttctttga tgacttctcc accttttttg attttcgctc caaggtcttc
    61261 aatcttaacg tttccttgtt cttcccgagc cgaaccaaaa atatcgcata agtaaacttt
    61321 atcagctaaa tcaagtgctt ctgcaaattc atccatcaat gcaatcgtac gcgtaaacgt
    61381 atggggttgg aaaactgcaa ttatttcttt atctggatat ttttggcgtg cgccatcaat
    61441 cgttgctttg atctctgcag ggtgatgcgc ataatcatcg actacggtca tgtctgctac
    61501 gatcttttca ctgaatcgac gttttactcc tgggaaagtc agcatttctt ctgcaacttc
    61561 tttcagatcc agtttttcga aataagctac tgcaataaca cctaaagcat ttaagatatt
    61621 gtgtttaccg aatgctggta cagtgaagtg cccaacaaat tcatccccat gatagacatc
    61681 aaaagcagaa ccagaagttg tgcgttcgat gtttcgtgct tggatatcat cgttttctgt
    61741 gacaccataa taataaatcg gcacatttgc ttttaatttg cgtaaataag catcgtcacc
    61801 atacgcaaaa atagcttttt tcacttgtcc agccattgtt tggaaagctg taaatacatc
    61861 gtcgatactt gtataataat ccggatgatc aaaatcgata ttggtcatga ttgcatagtc
    61921 tggtgaatag gcaaggaaat gacggcgata ttcacaggcc tcaaatgaaa agaattccgc
    61981 ttgcggatca ccatgtcctg ttccatctcc aattagataa cttgttggac ggacaccact
    62041 caatacatga gagagcagtc cagtcgtact tgtttttccg tgagagcctg ttacagcgat
    62101 actcgtataa ttttggataa aatgaccaat aaagtcgtga tagcgaatca cttccaaacc
    62161 taattctttt gctcgctgga tttcttcatg tgaatcagga aatgcatttc ctgcaatgat
    62221 cgtcatccct ggttttacat tatctgcgtt aaatggcaga atcgtgatat ttgctttttc
    62281 taaatctctt tgtgtaaaga aatatttttc aatgtctgat ccttggacat ttagaccttg
    62341 ttcatgtaaa acaagagcca aggagctcat tcctgaacct ttgataccaa caaaatgata
    62401 caatttattt tgattttcca tttgaatcct cttctcttat ctagcgtcca ttcttttagc
    62461 tattacattc aacacgctcc tcattatctt ataaacgatt gaaaatttca accaaattta
    62521 tttggaaagg aggattcgct tgctaaaatg gtcaagtacg agaaaaatcc gtttttattg
    62581 actctttaat tctggtgtaa gaagaccaaa cttcctctga tatatcaatg tgaggaataa
    62641 aatcttttcc tttcggacca tagccgttct catcgtcatg gagacgttcc atttctccta
    62701 atactagcgc atggaaatat tccttaggcc attgatgatt cagttctttt gctgtaaaga
    62761 tgatctcttc agaaaagtga aggatttccg gcacaaatgg cacagcattc gcgaaaatag
    62821 tttgttcatt ttgccatact ttctcaaaag ttgctcgagt cctgcgttgc agtgtcggat
    62881 cattcatcaa taagattttt tctggtacag ctcctaagga atgaagaatc tccagtgaaa
    62941 aagtggcgtt ctctccagaa tttgtagact tcgattctat cagaaaagcc ttatcgggca
    63001 aatcatagac ttcttttaga tactgacgac agatttcact ttcactcatg ccatcttcaa
    63061 aatgaaatcc ttgcttttca aaattctcat aaaggattct agtcgcatgc cccacccctc
    63121 cgaccaaaaa caattgatct acttggccat ttaaatacat ttgtgctgct ttatcagcta
    63181 agataggaag acagtttcca gctaaaataa gtgtaggtgc cgtcagttcc tcaaaatttc
    63241 cctcttcagg tgcggctaaa aaatttaata gctgattcca gtcttttaga ttcctctgct
    63301 cacttttttc caaaggcctt ctatcctttc atctgatttt ttgtgcttca ttaaagtctt
    63361 ctctttttgt ctcaatccat ttgatttctc catgacatct tccacaacga tatttgcgta
    63421 catcgattct tctcttgcgg cagatcgtgg cagaacaatc ttggcatcga taatactcca
    63481 tctttatctg tttcttcgtc aaggctggtg catagcgcaa ccctcctgtt tttttcaaaa
    63541 gatacttgaa atccatatct ttatgctgat accctcttcc agctagatga agatgataat
    63601 ggcaaagttc atgtttgatg attcctgcaa tcgtctcttc gtctgactct tcaaatagct
    63661 tcgcattaaa atctaaatga tgatcgttta aatgatagcg cccgccagtt gtacgtaagc
    63721 gtggattgaa cattgcttgg tgcttgaaag gaagctggaa gctttttaat gatatctctt
    63781 ctactaactg ctgcagttct tcttgtgtca atttttgtta ctcctcattg ttactcttca
    63841 taaggggaaa gcatcgtcaa actgattctg ccttttttcg tatcgacttg ttctatccaa
    63901 actgttacga tatctcctac tgacacgaca tctgtaggat gcttgacgaa ttttttgctg
    63961 agtttcgata tatggacaag tccgtcttgc ttcacaccga tatcaacaaa tgcgccgaag
    64021 tcaatgacat tacggaccgt tccagtcaat tccatccctg gtttcaagtc ttccatactc
    64081 aatacatctg tacgtaataa gggcgctggc atctcatcac gcatatctcg tccaggttgt
    64141 gtcagcccag ctaaaatatc ggctaacgtt tcttctccga ctgataggct ttcagccagt
    64201 ttctctacgg ataatcgtgt caatttttct actgcttctt ctgtaccaag ctctttttct
    64261 gaaagttgga ctgaagttaa tatttctttt gcaatagaat aactttcggg atggatacct
    64321 gtgttgtcca aaatgttttt cccaccaggg actcgcaaga atccgattgc ttgttcatat
    64381 gcttttggtc ctaagcgtgg cacttttttc aattgagttc gtgcggtgaa ttctccgttt
    64441 tcttcacgat aaatgacaat gttttgggca gttgttttat tcaatcctga tatatgctgc
    64501 aagagctgcg ggcttgctgt attcacatcc acacctactt ggttaaccgc tgtttccaca
    64561 acaaaatcca attgttcagc caaacgtttt tgagaaacgt catgttggta ctggcctact
    64621 ccgacagctt taggatcgat tttgactaat tcagctaaag gatcttgcag gcgacgggca
    64681 atagaaacag cacttctttc ttcaacttgt agatgcggaa attcttttcg tgcaatttcg
    64741 ctagcggagt aaacagaagc gcctgcttcg ttgacgatag cgtaataggt tttatggtcg
    64801 gcggatttca actgctcagc cacaaaaagt tcagattccc gactggctgt accatttccg
    64861 atagctacca tatctacttg atatttatta attaattgga taaaagctgg tccagcagct
    64921 tctctttttg cttgcgctgc aggtttatga ggataaataa cttcgattgc taaaactttc
    64981 cctgtcgcat ctacgactgc tagtttacat ccagtacgat aagccggatc aaatcccagg
    65041 acaactttac cttttagtgg cggttgcaac aaaagattac ggaggttttc gccgaaaata
    65101 gcgattgctt gctcatctgc cttttcagtc aattcattgc gcagttctcg ctcgattgct
    65161 ggctgaataa agcgtttata actatcctga taggcttctc tgacgaatga agaagaagga
    65221 gaggcaggat ttttgactat ttggcgatcc aagtaagcta aaattgctgc ttcatctact
    65281 tgaaagaata ctttcagaat atcttctttt tctccacgat tagtagctaa tattcgatga
    65341 gaaaccattt tatggacggg ttctgcaaag tcataataca tttcatatac gcctttttca
    65401 tctgcttgct catccttgac attgctgaca tacatacctt tgttatacgt ataagaccga
    65461 atccaagtcc gaaattttgc attatcgctg acttgttcag caataatctc atgagcaccg
    65521 tgcaacgctt cttcggcaga agagacttct ttttctttgt caatatattt ttctgcttca
    65581 gattgcacct ctccatctgt aagctgcatc agccacttcg cgagtggttc aagtcctttt
    65641 tctttagcaa tcgttgcttt tgtccgtcgt ttttgtttgt atggacgata caaatcttcc
    65701 acttgttgca ttttcacggc ttgggtgatt tctgcttcta actcgggagt cagtttccct
    65761 tgttcatcga ttagccgaat cacttcagtt ttacgttttt ctaagttttc aagataggca
    65821 taccgctctt cgatttcacg aatctggact tcatcaagac ttccagtcat ttcttttcgg
    65881 taacgcgcga taaaaggaac agtgtttcct tcatttaaca aattaagtac agtagtcaac
    65941 tgcttaggac gatagtctga aagttctttt tgtacaagct gaatgatcgt ctggttcaaa
    66001 ttttccgtca ttaaaatgcc tcttttctgc taaaaattgc ttctttattc tatcatactt
    66061 tttatcctgg gttaaactac tgaaagaaac aatattctct ataaaaataa aaagagccgc
    66121 aacaaagtca cagctccttc attctttcca ttagtcagat tccatgccaa ggtccttcgt
    66181 tgttctgata ttcaatatct tgaagaatac cttccttgtc aaaaacaacc ccatgcaatg
    66241 accctccgaa tacagcccca ccgtccattc cgattttatg atcctgaatc cagaggtctg
    66301 ttgtctgcat atctccatgg agcattggtg taatcgtatg tccaaataca attgtcttac
    66361 ctgtattgtt tttcccttca tgaaatggtt cccttatcca aataaagtct cttagacttg
    66421 tcttacgcca gtctttcttt gtcaaatcca caccggcatg gacaaaaaga taattttccc
    66481 attcataata caaggggcgc tggactaaaa atttaatcag ttctgaatat ctcgattgga
    66541 tcatcatcga gatttcagtt ggggagtatt cctccgatgc ccctgggtga atcaggcttt
    66601 caaacgtttc ttttccacca tttctcatat aaggcgcata ccagtcctcc ggtgattgca
    66661 gaaattgcaa aaaatattct tcatggtttc cccggaggta aatggctcct gtttcttcga
    66721 ctaattgctt tcctaataaa aaacattctt ttgtacgagg acctcgatca ttgagatccc
    66781 ctaataaaac aagctgatgg atctttggat cataatagtg aataagtttt tcaaaaagct
    66841 catgtttgcc atggacatcc ccaatagcat aaatcaatga tttcatgtgg atcaccatcc
    66901 tcaacgctag tatagcgcat attggaaatg gtcgacaatc aaaactattg ttttctattt
    66961 aattaaagct gtaaaccgca gttctgcttc ttctggagag attccatggt cttgaacata
    67021 gcgattgcgc ggatgtttcg cacactctat gctacatgct cctaaatgtt tttcttcatt
    67081 ttcaatggaa gcaagaatct gacgattgca ctcaggattg ctacaattga tatatcgttc
    67141 acatggtgtt ccgtcaaacc agtcgcgacc gacgatttgt ttatctactt ggttgatatc
    67201 gacagcgatc cgttcatcaa acacatacat cttgccgtcc cataattctc cttggacttc
    67261 aggatcctta ccataagtag caataccgcc atgcagctgt ccgacatctt tgaatccttc
    67321 acggacaagc caaccagaaa acttctcgca acgaatgcca ccagtacagt aggtcactac
    67381 ccgtttttcc ataaattctt ctttgtgctc gcggatccag tctggaagct ctcgaaaact
    67441 gcgtatatct gggcgtacag cccctcgaaa atgtcccaag tcatattcat aatcattccg
    67501 tgcatcaatc accactgtct gttcatctaa aatagcttct ttaaattctt gcggtgaaag
    67561 ataggcacct gtcacttggt ttggatcaat gtcctcttct agctttaaac ttacaagctc
    67621 tggacggtat cttacaaaca tcttcttaaa ggcatgtcct tcgcttggat cgatcttgaa
    67681 catcgtatca gcaaatcgag gatcagcttt cattgctttc atataggcag tcgtgttttc
    67741 aacggttcca gacacagtac catttattcc ttcttcagct actagaatac gacctttaag
    67801 atccaaagat ttgcaaaagg ctaaatgatt tttggcaaat tcctctggtt cttcgatttt
    67861 tgtataattg taataaagca gtacttgata atccatgtat ttcttccttc cttcttttcg
    67921 ttcctaaaca gtataaagaa ggcgttcgca tttgacgatt tatttgcttg tgtataatta
    67981 cgcatggaaa gttttttgtt tacataatat tattatttga attaaaaaga cttcgctttc
    68041 ctgtttcgca cagaaaaaca aagtctttat ttctattatt tacctgtaac cgcaaagtag
    68101 ttgccatcgg gatcagcaaa gttaaagaca tattcttctc caagctgtac catatcacct
    68161 aatgtgactg attgcgtctg cattttttta tatagtccaa agatatcttt actgtaaaac
    68221 atcaaagatg gggcactagt agctgtgcca ggtgaatggg actcaacaaa tgctcgatca
    68281 tataacagaa atgaggtttg actgtcctca actcctactt caattataag cgtcccatcc
    68341 atttcttgac gatctttttc cgcaaagcca actgctctcc aaaacgttgc atttttttct
    68401 acatcgtcca cataaagcat gatttttatt tcattcgtaa acatct
//
LOCUS       DADGKS010000006        66624 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.006, whole genome shotgun sequence.
ACCESSION   DADGKS010000006 DADGKS010000000
VERSION     DADGKS010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 66624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66624
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.006"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..164)
                     /locus_tag="JXV47_000387"
     CDS             complement(<1..164)
                     /locus_tag="JXV47_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAX1486456.1"
                     /translation="MTEEFYRWLLQLIREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRV"
     gene            complement(1041..1454)
                     /locus_tag="JXV47_000388"
     CDS             complement(1041..1454)
                     /locus_tag="JXV47_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HAX1486457.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            complement(1530..1826)
                     /locus_tag="JXV47_000389"
     CDS             complement(1530..1826)
                     /locus_tag="JXV47_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486458.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTREKPKFKVGDMVRCEA
                     EGFIYPFRGYVEKVLSNSAIIRIENTMECDKWLAKSKENLAVARLVDMEVIESK"
     gene            complement(1826..2032)
                     /locus_tag="JXV47_000390"
     CDS             complement(1826..2032)
                     /locus_tag="JXV47_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486459.1"
                     /translation="MKIYVVKFGNQFYRSDERSIGANTLSIVDILQSARWFDNLEEAN
                     QVSRRLGGLTQVYELVTVDHEGVE"
     gene            complement(2029..2226)
                     /locus_tag="JXV47_000391"
     CDS             complement(2029..2226)
                     /locus_tag="JXV47_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HAX1486460.1"
                     /translation="MNNRHRRVAKLRNQELNVAKVKFEREYGVSAEETYKVASQCVAD
                     ASDAIRKFGISILDIKWEDTE"
     gene            complement(2250..2555)
                     /locus_tag="JXV47_000392"
     CDS             complement(2250..2555)
                     /locus_tag="JXV47_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486461.1"
                     /translation="MNVQVYLKRDLARFPRSWDTNSHPSEAEEEGYLMSANMIEITRD
                     DADEFDKKRSWYSVPNPMYTAVIEDYHISDRFILIDLERPKKRIKQYRRCGFSTKKW"
     gene            complement(2722..3291)
                     /locus_tag="JXV47_000393"
     CDS             complement(2722..3291)
                     /locus_tag="JXV47_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HAX1486462.1"
                     /translation="MNKQEAIKKLESIKVIGNDALAACYNESINAGITLMKKIDEPKK
                     LVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLYSVIIAGEYLVKEISCSNEVKLVSTAYLPQYLAH
                     HYQLTEKQIKAIDERYWPFAVPVEEVAEG"
     gene            complement(3437..3772)
                     /locus_tag="JXV47_000394"
     CDS             complement(3437..3772)
                     /locus_tag="JXV47_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486463.1"
                     /translation="MIILATDYIDSLKDENGNVPALLNCGIKSKNRIILLRISADLAK
                     YLYLSKTAVYYTAATRYQYKGKTISQDYYDRLISPDIHGKSKSAIKLFGAIEIYADDF
                     PNLWLKEEQ"
     gene            complement(3769..4155)
                     /locus_tag="JXV47_000395"
     CDS             complement(3769..4155)
                     /locus_tag="JXV47_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486464.1"
                     /translation="MIPRFRSWYTPFKGKTIGQEMKYGQAGRLITHAEMAPDKYVLMQ
                     STGLKDKNGVEIFEGDVVLVNVSNGFDHLVNEKTVVQESEFHSGLVCKSLISGMEYRI
                     FSHQKMGYEYEVTGNIHENSELLEVE"
     gene            complement(4152..4469)
                     /locus_tag="JXV47_000396"
     CDS             complement(4152..4469)
                     /locus_tag="JXV47_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HAX1486465.1"
                     /translation="MNLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILDEYME
                     GSK"
     gene            complement(4469..4774)
                     /locus_tag="JXV47_000397"
     CDS             complement(4469..4774)
                     /locus_tag="JXV47_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486466.1"
                     /translation="MSVDKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWTEKTR
                     RRMPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRAKNMDIDSKGRQFRYVEEK"
     gene            complement(4771..4932)
                     /locus_tag="JXV47_000398"
     CDS             complement(4771..4932)
                     /locus_tag="JXV47_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAX1486467.1"
                     /translation="MTTEEVIQMRIRSIQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            complement(4947..5306)
                     /locus_tag="JXV47_000399"
     CDS             complement(4947..5306)
                     /locus_tag="JXV47_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HAX1486468.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            complement(5303..6154)
                     /locus_tag="JXV47_000400"
     CDS             complement(5303..6154)
                     /locus_tag="JXV47_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAX1486469.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALERAKSFVNDVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            complement(6171..7004)
                     /locus_tag="JXV47_000401"
     CDS             complement(6171..7004)
                     /locus_tag="JXV47_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer"
                     /protein_id="HAX1486470.1"
                     /translation="MSDNKRYYYLKLKENFFDSDEMVLLESMPDGYIYSNILLKLYLR
                     SLKHEGKLMFNDRIPFNSTMLATITRHSVGVVEKAVQIFRDLQLIDVLDNGAIYMSDI
                     QSFIGKSSTEADRKREYRKKIEEAKRNLITGGQVSDKCPDKTTPELEIEIEKDIDIDK
                     EEKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEY
                     VINWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKNNHKKQSQKLQYSNPSEYDDLP
                     I"
     gene            complement(7011..7697)
                     /locus_tag="JXV47_000402"
     CDS             complement(7011..7697)
                     /locus_tag="JXV47_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486471.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIDRLKTMYDGYDGD
                     RIIEVRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHNIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            complement(7703..8449)
                     /locus_tag="JXV47_000403"
     CDS             complement(7703..8449)
                     /locus_tag="JXV47_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HAX1486472.1"
                     /translation="MSEKEQPLKNRSDNTLFNTLYKINVKDVTEKRNNLTYLSWAWAW
                     AEVSKVCEAVDYEIYHDPETYLPYVFDKKTGYMVFTSITVNGVKRDMWLPVMDGANKA
                     MKDEPYTYEVNDYQWNNETKKKEIVGKIEKRVEAATMFDINKTIMRCLVKNLAMFGLG
                     LYIFAGEDMPEDVSMLEPATQRSKKLFLDALQLVANKYEKSIDEAIVALTDAASITAD
                     DSKWTKRDLGILKRGVNWIEDQYREETKEK"
     gene            complement(8442..8783)
                     /locus_tag="JXV47_000404"
     CDS             complement(8442..8783)
                     /locus_tag="JXV47_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486473.1"
                     /translation="MKKELSTLDQYLTDPSWGKSNIKETSNRKIRRNLLTDEELACDQ
                     DDLGNFVSIWDHVYLIHLSRKSKKTEYIYVIEDGLIDALEEYDRDNLIDISYYGSGKK
                     YIAEMEAEFDE"
     gene            complement(8962..9669)
                     /locus_tag="JXV47_000405"
     CDS             complement(8962..9669)
                     /locus_tag="JXV47_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HAX1486474.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFDKKHRHVLTAIDELKEGVAEN
                     WADLFWEDTYVHPQNKQSYRIIYMNRDGFSLLAMGFTGKKALSFKLQYIEAFNKMEKE
                     LKDQLPSIPATKREMALLALAANEETNERVDAIESDLNDLKNNQLLAEPDYRTISNMV
                     RNKIRVICNQQHLNSKAKAELFKDLNGGIKRITGAVARNRIKAKQFDDVIDFINNWMP
                     STATMTIIKQMELLEDE"
     gene            9714..10193
                     /locus_tag="JXV47_000406"
     CDS             9714..10193
                     /locus_tag="JXV47_000406"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486475.1"
                     /translation="MSRKIDNIILLTTIFYLVIGATLSLLSFLSNSSLIVLNQKSILT
                     EFAHIDYFSFFKTGLICLFLSSFILYIGTTFCLMVLNLKMFIIEKWIVIIAKIFSSIS
                     IIIPMTLTFSKEQFNVATTFVSFIALFSFAVPKTFQSKSSNAKVNVENTDRKNDESY"
     gene            complement(10422..10721)
                     /locus_tag="JXV47_000407"
     CDS             complement(10422..10721)
                     /locus_tag="JXV47_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486476.1"
                     /translation="MKKPTLSELIEAAEKAVKPDDWYRQSLILEKFHGMSKTTLVEYC
                     KEMETIPEFAEGILRPGHSTTFIHYHTFIWFLKWKDANKYRVKSLSPSDVLKEAS"
     gene            complement(10826..11029)
                     /locus_tag="JXV47_000408"
     CDS             complement(10826..11029)
                     /locus_tag="JXV47_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1486477.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            complement(11044..11790)
                     /locus_tag="JXV47_000409"
     CDS             complement(11044..11790)
                     /locus_tag="JXV47_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HAX1486478.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVADVLGYSNPQKAIR
                     DHVDLEDKTQNDSFTVNGTAVVLINESGLYSLILKSKLPSAKKFKRWVTSEVLPTIRK
                     TGSYSNVPQSFAQALRLAADLEEKNQLLEQQIAEYEPKISYLDTILSSTDTVATSQIA
                     ADYGMSAIALNKLLNELGVQHKVSGQWILYRKHMNQGYTKSHTSEIPKADGGTKVVMN
                     TKWTQKGRVFIYNLLIAEGYYPQMDLEEIG"
     gene            11868..12176
                     /locus_tag="JXV47_000410"
     CDS             11868..12176
                     /locus_tag="JXV47_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486479.1"
                     /translation="MKPEFVITMLDGEKIKIFADTLVVGYDDASNIEEKDGMFYSSQI
                     YVNTLQGDIGVSTLATSRPLVGLIGFLSKATFFSLGDDIDSDETVIYKTSAVKSIGFK
                     "
     gene            complement(12147..12404)
                     /locus_tag="JXV47_000411"
     CDS             complement(12147..12404)
                     /locus_tag="JXV47_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="HAX1486480.1"
                     /translation="MNKEMSQTIKVQKMIDDLTHGIDSQADKIIKELQGQKVKDAKML
                     LKTINFEMNPTKRKLADVLEEKLASAINEQELLFETDTFNS"
     gene            13136..13456
                     /locus_tag="JXV47_000412"
     CDS             13136..13456
                     /locus_tag="JXV47_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1486481.1"
                     /translation="MITFERIKELAKKQGKSLNKVEEDLGYGKNVLYRLKNSNPSTER
                     LQEIADYFDVSVDYLLGREEKETPKHVDLSENDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            13474..13905
                     /locus_tag="JXV47_000413"
     CDS             13474..13905
                     /locus_tag="JXV47_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAX1486482.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            14032..14616
                     /locus_tag="JXV47_000414"
     CDS             14032..14616
                     /locus_tag="JXV47_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HAX1486483.1"
                     /translation="MAKKVMGQDGKMYKVSKPFYKKVWFWVLAVILIIIIGSALNGGS
                     DSNKASDNGGEKVTKSSTSASSSKEEKSDTFYKIGDTVKVGDAEYTLNSVELTDERNQ
                     FEENQPAQVVKITYTVKNDGDSDIPVGTDVEVYGPDDKKSETYANENTMGSVAPGKQM
                     DVTAHFTLNQKGEIEIHFSPLVSFEKAAIFKATV"
     gene            14718..15866
                     /locus_tag="JXV47_000415"
     CDS             14718..15866
                     /locus_tag="JXV47_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAX1486484.1"
                     /translation="MLKVWVEQTKDGQFKFIERYVDPYTEKTRKKSTTLTSNSPQAWK
                     KAQKILDKKIKEALENYNKSDITFGELYKEWYEYYKQHVKRTSYLKVPMMMKHVSKHI
                     SDDTIVRNIDETLINKMIEDMYTFGDLSLNYTKQTKTTLSVMLNYAIDRKYIQRNPAL
                     AVKIHPKKVEEEKRKLSMDKKYLEKEEIDQILKQLYSNPRRKLHGIIAEFLYLTGLRY
                     GELLALQMKDYGEGKISINGTLDYTSVKMDNAIKTTPKNTYSQREVQLSNRAKELIES
                     VIADNILAGRPTNPDQYIFISTNGTPLTLHSFNAVLHKVEEELELEKNLSSHIFRHSH
                     VSLLSELGVPLKAIMERVGHSDANTTLSIYNHVTKKAKQQVIDKLNRL"
     gene            complement(15955..17580)
                     /gene="groL"
                     /locus_tag="JXV47_000416"
     CDS             complement(15955..17580)
                     /gene="groL"
                     /locus_tag="JXV47_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HAX1486485.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDATIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
     gene            complement(17631..17915)
                     /locus_tag="JXV47_000417"
     CDS             complement(17631..17915)
                     /locus_tag="JXV47_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HAX1486486.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            18140..18802
                     /locus_tag="JXV47_000418"
     CDS             18140..18802
                     /locus_tag="JXV47_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAX1486487.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            complement(18878..20170)
                     /locus_tag="JXV47_000419"
     CDS             complement(18878..20170)
                     /locus_tag="JXV47_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1486488.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQHLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            20340..20969
                     /locus_tag="JXV47_000420"
     CDS             20340..20969
                     /locus_tag="JXV47_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HAX1486489.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAASDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            complement(21072..21881)
                     /locus_tag="JXV47_000421"
     CDS             complement(21072..21881)
                     /locus_tag="JXV47_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAX1486490.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(21936..22805)
                     /locus_tag="JXV47_000422"
     CDS             complement(21936..22805)
                     /locus_tag="JXV47_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486491.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            complement(22806..24122)
                     /locus_tag="JXV47_000423"
     CDS             complement(22806..24122)
                     /locus_tag="JXV47_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486492.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            complement(24119..25954)
                     /gene="walK"
                     /locus_tag="JXV47_000424"
     CDS             complement(24119..25954)
                     /gene="walK"
                     /locus_tag="JXV47_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HAX1486493.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVILSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            complement(25959..26663)
                     /locus_tag="JXV47_000425"
     CDS             complement(25959..26663)
                     /locus_tag="JXV47_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1486494.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            complement(26853..27713)
                     /locus_tag="JXV47_000426"
     CDS             complement(26853..27713)
                     /locus_tag="JXV47_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAX1486495.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITPEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            complement(27700..28269)
                     /locus_tag="JXV47_000427"
     CDS             complement(27700..28269)
                     /locus_tag="JXV47_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HAX1486496.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            28650..28722
                     /locus_tag="JXV47_000428"
     tRNA            28650..28722
                     /locus_tag="JXV47_000428"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:28683..28685,aa:Lys,seq:ctt)
     gene            complement(29218..29604)
                     /locus_tag="JXV47_000429"
     CDS             complement(29218..29604)
                     /locus_tag="JXV47_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HAX1486497.1"
                     /translation="MNKRKTEFILILISGITGILCSLLALMGGMFLSSIDSTTLNTTE
                     LTSKDIDMLVNLSGNVVLFGGITLVFSIMIFIIGFLVRKNQKTVVYGISLLILSIIPF
                     FLLTLLWVIPGVLGIIAGLMLLIRKS"
     gene            complement(29601..30122)
                     /locus_tag="JXV47_000430"
     CDS             complement(29601..30122)
                     /locus_tag="JXV47_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HAX1486498.1"
                     /translation="MNKKSGIETLPNYVFAGFWLRFFAFLIDLICISIITHATIGLFY
                     KIMGLESDKSIITFYGIASLAIYLTYFVLLTKLNSGQTIGKMIFGIRVVSFEEKELSW
                     QTIFIRECICRFILKNFVFQIGYLVAAFTPKKQHIGDYFSNTSVVVIRSLEAINYGQK
                     ISNSKTLNLERIK"
     gene            complement(30124..31158)
                     /gene="sppA"
                     /locus_tag="JXV47_000431"
     CDS             complement(30124..31158)
                     /gene="sppA"
                     /locus_tag="JXV47_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HAX1486499.1"
                     /translation="MNKRRWIAVGVACGLLLLSIIVALIPGKDKEEASNTTLTGINKI
                     FYGSNEITEETLEEGASNKKIVKLSVNGVIADTGESNLFSREQYNHQNFLTQLKKIQE
                     DKAVKGVLLEVNSPGGGIYESAEIAKEMAKIKKLDIPIYTAFKNTAASGGYYISAGSD
                     KIFATEETTTGSIGVIISGLNYSGLLEKLGVTDATYKSGALKDMMSPQHKPSEEENKV
                     IQEFVMSAYDRFVNVVAKGRNMDTNAVKELADGRIYDGNQAVENGLVDQIGYSEDALD
                     SLKKEKKLTDATVIEYKNDTTGFASSWLGNKIAEWQGLKATTSDRVISVFEKLGFSDT
                     PKPMYYYGGL"
     gene            complement(31191..32606)
                     /locus_tag="JXV47_000432"
     CDS             complement(31191..32606)
                     /locus_tag="JXV47_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HAX1486500.1"
                     /translation="MVSIKNYGKSRRGKQFMQNNNWFEHSSIYTKQHHSFYRWVLYPV
                     ILFLCIIGLFLTFAKKEVVIRTTAQLNPEKIEKLQVPLEAKIMENFLKENQFVHKDDV
                     LVRLDCSLIENEKAQIEQENQRITQQIKMAQLFIESISKGKNLFSTDDSFGYSNQLKS
                     MLSEKESLRYALKQSELNDQKQLEVYEKTKRQLEKQIESSDSKLQEWQQVQVAWSNNQ
                     SLKDFSKEMMANYENWQEQLNNVSDDQKNQVKLTISASINEQIEQLKKEVEQYQSEKA
                     KLVKPTTSENDRISQTEKGKQELEQAITTVKQTVTELNEKQEKNQSVIKSLDDQLSKG
                     ILKAPVSGTVHLNEETKGQAELAKGTVLAEIYPIHEKSKMKFTALLPANESTYIKEGM
                     KVHFKLDQKGGAPITIDGTLDEISENSTATEKGVFYAVKGTLKTTQSFPFRYGLTGEL
                     SLIVGEKTYWQQIVDVFLNKK"
     gene            complement(32575..34728)
                     /locus_tag="JXV47_000433"
     CDS             complement(32575..34728)
                     /locus_tag="JXV47_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HAX1486501.1"
                     /translation="MIKSFPFVQQQDEKDCGVACLSMILKYFKTDIPIHKLRDLSGTD
                     LEGTSAFGLKKTFEKLSFDCMAIQADSEIWKERDLILPLIAHILVDNSYMHYVVIYKT
                     KGNVLWIADPANGKNRKTIEAFQKEWTGILLLPMPRETYIPIKEKVAGLSSFLPIIWK
                     QKGLVFHIVLASIFITFFGIGSSYYFQGILDFFIPNQARSTLNIISIGLIAVYLFRVL
                     FEYSRSYLLIILGQRMSMAIMLQYFKHVLTLPMNFFATRKSGEIISRFLDASKIIDAL
                     ASATLSIFLDIGMVLLVGVTLAIQNSTLFLITLCSLPFYVVAIFAFVKSYEKSNREEM
                     AAGAAVNSSIIESLKGIETIKAYSGEEKVYNRIDHEFVKLMKKSFRTVTLDNIQQGIK
                     HLIQLISSALILWLGSYFVMDNRISLGQLITYNALLVFLTDPLQNIINLQVKMQTAQV
                     ANNRLNEIFAIDSEKSNQSFEYMLSEQLFQQDITVKNVSFSYSMKAPTLNEISCTIPS
                     HSKTAIVGVSGSGKSTLAKLFVRFYEASEGSIHYGNINHLDIPFQILRDRVTYLPQES
                     FFFSGTIIENLIFGLDSPPSFEQIIEVCEIVQLNEFINQQPLRYETLLEEGGNNLSGG
                     QRQRLALARALLKNPDILILDEATSGLDTLLEHAIMNYLLNLKEKTIIFIAHHLPIAK
                     ACDQILVLHEGHLVEKGTHDELRFADGIYQKLWEI"
     gene            34986..35222
                     /locus_tag="JXV47_000434"
     CDS             34986..35222
                     /locus_tag="JXV47_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HAX1486502.1"
                     /translation="MFKHAKCKGTKYCGNAQTVGGGNNAWGKLGQVVGGLTTGAVGGA
                     GLGTAICGPACGVVGGLYGAVAGGAAAGWDARKK"
     gene            35241..35456
                     /locus_tag="JXV47_000435"
     CDS             35241..35456
                     /locus_tag="JXV47_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HAX1486503.1"
                     /translation="MHIKNTKTTFILSSEELKNIQGGSAVGVLGTTFSGATAGVKLCS
                     AGGPYAIAACGVGGALLGAGFSMWTGA"
     gene            complement(36159..36911)
                     /locus_tag="JXV47_000436"
     CDS             complement(36159..36911)
                     /locus_tag="JXV47_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1486504.1"
                     /translation="MSYPIILCEDQIIQLNQLERIIDNFILFHDKVFKIVLKTQSPLE
                     VKKYLKQFRPKQGIYFLDIDLNHEVNGIELAEVIRKYDVQAKIIFTTTHDEMLPVTIK
                     RRVETLGFVTKDQTLDEYRNEIVELLLLAQERIDATKQVTNQAFVFSIGSQTFTFDIN
                     DIYFVEASKLPHRLSLCTKDGQYEFYGRISELEKKYPMLTRISRACLVNIFNVKEIDF
                     KKRSLYFDSELARNFTLGKAQKIKEKLKESTV"
     gene            complement(36926..38173)
                     /locus_tag="JXV47_000437"
     CDS             complement(36926..38173)
                     /locus_tag="JXV47_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAX1486505.1"
                     /translation="MFVGNFFFFLLFYMTNTDLNKRKYLFVCLLIPLTFFVELFTDVS
                     AAIPIIGSYFILKEKKKTNIVLLNKLLLCMLIDDFRSIITSMVMTYMFSFEGIKGYGY
                     VVFQIMLDSLFLLMFIWLYRKLAINRIVEQSSSKLTAIFMIYLLTIGLFVSYVAHQYQ
                     VFDHFVFGVLIFLIIQMFVVLFLFIRITIRQREQYEQQLKRKELVYLKKYTDSLEKDQ
                     EKFARFRHDYKNLLLSLKEIANQNHDSILEKEIKELEIYSNSYLTNKFEYRYLKNIKN
                     EYLKSLLIAKLYQANNNKICCKFECPSTIIEVPVPIFDCIRVLGIILDNAIEASIESQ
                     DRELSLAIYRDDKQIEISISNSCREILLSIDTLMKKGITTKKGHQGLGLSSIEEINKK
                     NPNMFVNYQNDPYQFTTQVILLF"
     gene            complement(38249..38395)
                     /locus_tag="JXV47_000438"
     CDS             complement(38249..38395)
                     /locus_tag="JXV47_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HAX1486506.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFSLF
                     KKCN"
     gene            complement(38499..38810)
                     /locus_tag="JXV47_000439"
     CDS             complement(38499..38810)
                     /locus_tag="JXV47_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAX1486507.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPGPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(38812..39009)
                     /locus_tag="JXV47_000440"
     CDS             complement(38812..39009)
                     /locus_tag="JXV47_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterocin"
                     /protein_id="HAX1486508.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(39403..41130)
                     /locus_tag="JXV47_000441"
     CDS             complement(39403..41130)
                     /locus_tag="JXV47_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAX1486509.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(41123..42316)
                     /locus_tag="JXV47_000442"
     CDS             complement(41123..42316)
                     /locus_tag="JXV47_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HAX1486510.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(42503..43147)
                     /locus_tag="JXV47_000443"
     CDS             complement(42503..43147)
                     /locus_tag="JXV47_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAX1486511.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(43241..43375)
                     /locus_tag="JXV47_000444"
     CDS             complement(43241..43375)
                     /locus_tag="JXV47_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HAX1486512.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(43377..45509)
                     /gene="feoB"
                     /locus_tag="JXV47_000445"
     CDS             complement(43377..45509)
                     /gene="feoB"
                     /locus_tag="JXV47_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HAX1486513.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(45506..45979)
                     /locus_tag="JXV47_000446"
     CDS             complement(45506..45979)
                     /locus_tag="JXV47_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HAX1486514.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            46380..46604
                     /gene="nrdH"
                     /locus_tag="JXV47_000447"
     CDS             46380..46604
                     /gene="nrdH"
                     /locus_tag="JXV47_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HAX1486515.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            46763..48922
                     /gene="nrdE"
                     /locus_tag="JXV47_000448"
     CDS             46763..48922
                     /gene="nrdE"
                     /locus_tag="JXV47_000448"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HAX1486516.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFLSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYAMAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            48972..49937
                     /gene="nrdF"
                     /locus_tag="JXV47_000449"
     CDS             48972..49937
                     /gene="nrdF"
                     /locus_tag="JXV47_000449"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HAX1486517.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(50026..51165)
                     /locus_tag="JXV47_000450"
     CDS             complement(50026..51165)
                     /locus_tag="JXV47_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAX1486518.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAV
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(51474..52187)
                     /locus_tag="JXV47_000451"
     CDS             complement(51474..52187)
                     /locus_tag="JXV47_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HAX1486519.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(52441..53142)
                     /gene="nagB"
                     /locus_tag="JXV47_000452"
     CDS             complement(52441..53142)
                     /gene="nagB"
                     /locus_tag="JXV47_000452"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HAX1486520.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            53376..54908
                     /locus_tag="JXV47_000453"
     CDS             53376..54908
                     /locus_tag="JXV47_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAX1486521.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(55099..56301)
                     /locus_tag="JXV47_000454"
     CDS             complement(55099..56301)
                     /locus_tag="JXV47_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAX1486522.1"
                     /translation="MKSNEKKPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMAALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTVFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQTVVFKG
                     KRNLENKK"
     gene            complement(56383..57072)
                     /locus_tag="JXV47_000455"
     CDS             complement(56383..57072)
                     /locus_tag="JXV47_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAX1486523.1"
                     /translation="MKKKIIRLILISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(57178..57546)
                     /gene="rplL"
                     /locus_tag="JXV47_000456"
     CDS             complement(57178..57546)
                     /gene="rplL"
                     /locus_tag="JXV47_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HAX1486524.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(57599..58102)
                     /locus_tag="JXV47_000457"
     CDS             complement(57599..58102)
                     /locus_tag="JXV47_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HAX1486525.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     gene            complement(58512..59201)
                     /gene="rplA"
                     /locus_tag="JXV47_000458"
     CDS             complement(58512..59201)
                     /gene="rplA"
                     /locus_tag="JXV47_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HAX1486526.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(59305..59727)
                     /gene="rplK"
                     /locus_tag="JXV47_000459"
     CDS             complement(59305..59727)
                     /gene="rplK"
                     /locus_tag="JXV47_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HAX1486527.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            60070..60738
                     /gene="sdaAB"
                     /locus_tag="JXV47_000460"
     CDS             60070..60738
                     /gene="sdaAB"
                     /locus_tag="JXV47_000460"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit beta"
                     /protein_id="HAX1486528.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            60751..61623
                     /gene="sdaAA"
                     /locus_tag="JXV47_000461"
     CDS             60751..61623
                     /gene="sdaAA"
                     /locus_tag="JXV47_000461"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HAX1486529.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(61714..62733)
                     /locus_tag="JXV47_000462"
     CDS             complement(61714..62733)
                     /locus_tag="JXV47_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAX1486530.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(62906..63793)
                     /locus_tag="JXV47_000463"
     CDS             complement(62906..63793)
                     /locus_tag="JXV47_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAX1486531.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(63870..64415)
                     /gene="nusG"
                     /locus_tag="JXV47_000464"
     CDS             complement(63870..64415)
                     /gene="nusG"
                     /locus_tag="JXV47_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HAX1486532.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(64516..64686)
                     /gene="secE"
                     /locus_tag="JXV47_000465"
     CDS             complement(64516..64686)
                     /gene="secE"
                     /locus_tag="JXV47_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HAX1486533.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(64710..64862)
                     /gene="rpmG"
                     /locus_tag="JXV47_000466"
     CDS             complement(64710..64862)
                     /gene="rpmG"
                     /locus_tag="JXV47_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAX1486534.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            65024..65668
                     /locus_tag="JXV47_000467"
     CDS             65024..65668
                     /locus_tag="JXV47_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAX1486535.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(65724..66227)
                     /locus_tag="JXV47_000468"
     CDS             complement(65724..66227)
                     /locus_tag="JXV47_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAX1486536.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(66240..66286)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
BASE COUNT        19838 a        13539 c        11033 g        22214 t
ORIGIN      
        1 tctactctat gatacttacc tagtcttcta cactcttggc attcatagtg atctcgtttc
       61 atcgctttct ctctaagcct gcgccattta ggagactgat agaacttaac taaacgatct
      121 tctcttatca actgtaatag ccatctatag aattcctcgg tcatattccg tctcctttcg
      181 caatcttatt taatgcttag ctattctttt gccatacaat ggaataactt cattgctttc
      241 ctttcgtttg tatgtatcgc tctttattgg tcttctatac tttcgtacta tctcaccgtt
      301 accgttttgc acagtgatta cttcatactt ctgttctaag tattgtggtc tatacattct
      361 tgttacctcc tttgtgtaaa ataaaaagac cactcaaaga gtgatctaat ctgtaaaaac
      421 tacacctcat aaacgagatg cagttatagc tctatcaagc aacctacacc gattccatcg
      481 attactatcg acctcgcctt gctcgtgtac tttgagcgcc catttccaac cctcggttgc
      541 caaagtcact ggcaatgaat cgaacattgc atggtcaaat cataaaacgt taaggctatc
      601 cctcgacgta ttgaccttat ttttaagcgt ctaccctttc cgccacagtg acactataaa
      661 attattcttg gctgctacta ttttttattt tgcccatttt taaatccaat catatagaca
      721 ttaagacaga gcgcaaaaat tgaaattatt aatggaatca tttctcttca ctcaccttta
      781 gttatcgtgt gaataattaa aaaaacaata gacagcaacg gatgatagat aataagaaca
      841 atttagaagg agttgaaatt cacatcctta ttcttaatat ttccgttgct gtctatcgaa
      901 gcttaattgt gaaacaataa taaaacgatg ttccttttat tattattttg tctcagacct
      961 atcactaatc tttcgacact accataatat cactggtaaa tagctaaaaa ccgccatcat
     1021 tccgccaaaa aaccgccaaa ttatttataa gcaattattc ttccgtgttt atatgcttct
     1081 gcaaactcta ttagagcttc cgacttcatc cgttgtatac ttctttctga ataacccact
     1141 tcacggctaa ttctgtagtt tgagaagcta tctggcacac aaaagctgta gtagagtatc
     1201 tgacggctaa tcagactaag agccatcaaa gccgctaaaa tcgcatctct ctctgcttct
     1261 atatccatca tctgaatgat cgcgtcctct gccttattgc cgtgcttcgg cgccttcggc
     1321 atatccgtaa taattggaga cttaatatct atcaaagagc gacctgccat ccgctccaaa
     1381 cgccgaaagt tcttcagcac atctctcgca ttacatcttg tctgtttgaa atctacctct
     1441 cgtaacaatt gcatcaagtc aaaccgctcc tttatgtgat ataataaact tgtctgtttt
     1501 attatgttag tcggagcgat ccggcttttt tatttgctct cgattacttc catgtcaact
     1561 aatctcgcta cagctaaatt ctctttgctt ttcgctaacc acttgtcaca ttccatcgtg
     1621 ttttcaatac gaatgattgc tgagttcgac aatacctttt ctacatatcc acgaaatgga
     1681 tagataaatc cttctgcttc acagcgaacc atgtcaccga ctttgaattt tggtttctca
     1741 cgtgttttag ggttctttgt cggcatatct agcatcaaac cgccgatacc atgactacta
     1801 gcgtaaaatc cgtcttttag tttcattact ctaccccctc atgatcgaca gtgaccagtt
     1861 catatacttg cgttaatcca ccaagtcgtc gtgaaacttg gttagcttct tcgagattat
     1921 caaaccatct tgcgctttgg agtatgtcta caatggataa tgtgttagcc cctatagaac
     1981 gttcatcgct tctgtaaaat tgatttccaa actttactac ataaatcttc attctgtatc
     2041 ctcccattta atatctagta tcgaaattcc aaacttacga atagcatcac ttgcatcagc
     2101 aacacactga cttgccactt tatatgtttc ttctgcagaa acaccatact cccgttcgaa
     2161 ctttactttc gctacattca gttcttgatt tcttagtttt gctactctgc ggtgtctgtt
     2221 gttcattttt cttcacctct gttttgttat caccatttct ttgttgaaaa tccacaacgt
     2281 ctatactgtt taattcgttt cttaggcctt tctagatcaa tcagaataaa tctgtcggat
     2341 atatgataat cttctattac agccgtatac attggattcg gaaccgagta ccatgatctt
     2401 tttttatcaa actcatccgc atcatctctt gtaatttcta tcatgttagc agacattaga
     2461 tagccctctt cttctgcctc ggatgggtgg gaatttgtat cccagcttcg aggaaacctg
     2521 gccaaatctc tttttaaata aacttgaaca ttcattccgc ttcctcctca tcgatctcta
     2581 tctcgacatc tctgccttct aaaatctgtt tggtatcaat gctttttgtt ttcaacgcca
     2641 acccaccgtc tttttgtgca gcaacaatgg taatcgtcat tgcctttgtt ccgtctggta
     2701 tatggagcat tatctgtcta ctcatccttc cgccacctct tccactggca cagcaaatgg
     2761 ccagtatctt tcatcaattg ctttgatctg tttttcggtc agttggtagt ggtgtgcaag
     2821 gtattgtggc aggtaagctg ttgatactag tttaacttca ttactgcaac tgatctcctt
     2881 gacaaggtac tcgccagcaa ttattacact gtacaacggc tctttctcga cctcgtagcc
     2941 gttgtacaag ctcaatagtg tttcatatga ttgtctcgtt gcccaagcga gtaattcttc
     3001 tccttgttct tgcgtcacta tgccatctcg tacaaaccaa tcacagaaat aatatgaatc
     3061 accatcttta gatttgatta aatacgctat tttttcagct ttcgtaaaag ggtccgtaga
     3121 tttctcaagc caaccggcca cgagttgtgg aataactagc ttcttcggtt cgtctatttt
     3181 tttcattaac gtaatacctg catttatact ctcgttatag caagcagcta gtgcatcatt
     3241 tcctatcact ttaatacttt ctaacttttt gattgcttcc tgtttattca tcgctgttcc
     3301 tcctaaaaaa ttaactgcca aagcaatata atcactttca atgatacaaa tcccaccagt
     3361 gcaataatta cagatataaa cgcacagttt atgaaacagc caactaaggc gcttgcttct
     3421 tctaaccagt ctttcattac tgttcctcct tcaaccataa atttggaaaa tcatcggcat
     3481 atatctctat tgcgccaaat aacttgatcg ctgattttga ttttccatgt atgtcaggac
     3541 tgattaaacg atcataataa tcctgactga ttgtttttcc cttgtactga taacgtgtag
     3601 ccgcagtgta atatactgct gtcttgctca gataaagata ttttgctaaa tcagccgata
     3661 tccgtaacaa aatgattcta ttcttacttt taattccaca atttagcaat gctgggacat
     3721 tcccattttc atcttttaaa gaatcgatgt agtcagtagc taagataatc actctacctc
     3781 caataactcg ctattctcgt gtatatttcc ggtgacttca tattcgtatc ccatcttttg
     3841 gtggctgaat attctatatt ccattccact aattaatgat ttacaaacta atccggaatg
     3901 aaactcggat tcttgtacaa ccgttttttc attaactaaa tgatcaaaac cattacttac
     3961 attaaccaga actacatccc cttcaaatat ttctacgcca ttcttatctt tcagtcctgt
     4021 ggattgcata agcacatatt tatctggagc catttcagca tgagtgatca accttcctgc
     4081 ttgcccatat ttcatttctt gtccaattgt tttaccttta aatggtgtgt accacgatcg
     4141 aaatctcggt atcatttgct gccctccatg tattcgtcta atatctcttt atatttctct
     4201 acaaatttga aacgatcttg atgaagtttc ttgctccaat ttgtttgccg atccagctca
     4261 cgcatttgat cgaacccttt ttgaatttcg ttgtaataaa attcaatgtt tgctgctgcc
     4321 ttccaatgcc tgctacttcg cactcctgcc cctgtttcag ccatttccaa cttaactaat
     4381 tccgctcgtt cttttgattt tttgtctttc tgaatcttca tcatgatttt cttgaggatg
     4441 atatcactgt attgtgtaat gagattcatt atttctcctc cacataccta aactgtcttc
     4501 ctttagaatc aatatccata ttcttcgctc tatcccagat gatgtttttg ctcagaccag
     4561 taatttcaga taactgttca gcggtacctg ttactagaat tcggtcaccg tgccagattg
     4621 caatttttct cggcattctc cgtctggttt tttcagtcca cattgattta ccgagctttt
     4681 ggacttctgc aactatttct ttgtcttctt gccaattctc agaatgtgtc agttcgatga
     4741 ttcgtttcat tgctgctttc ttatccacgc tcattcctcc aatctacgaa tttcccttct
     4801 taagttctct atgtgcaaat cgattgcctt tctcgccgtt tcattgacca tcactgcctt
     4861 tgttcgttcc agatcgtcaa tctcacgttg aatgcttcga attcgcattt gaatcacttc
     4921 ttctgttgtc atgatagacc acctctttaa aaacgctctt ccttgaacgt attccgatat
     4981 tttttagcta atatcaacgg cacttgatat tgatgacaaa acagctttgc cttgatctta
     5041 aagtcttttg tctgcattcc tttaacatct acgactttga caagtttgcc gtttttataa
     5101 aatgtgaagt cgggaatata ctcgatcttg cgatacttct ttccgtctag ttcaaatttc
     5161 ggcatcagct caaatctttc ctgaagtttt actttccagc cattcgcttc agcttgccac
     5221 aaggctagat cgtaatactc tgcttctgcg atagaatcaa acttgatacc tcgatgaaca
     5281 gtttttttat tacggtattt attcatgcga tactaccttt cactggtttt atgcgcttgt
     5341 ctgctgtttg ctggaatttc agcgcataac cttctgaatt cttaaatatc ctagaaacaa
     5401 ttctttcacc gtaggcttct cttagttcag gaccagataa gtttgttgtg atgatcgttg
     5461 ccttgttctg tcttgcttct aagagcgtgt ttaacgtgtt gtttgtaaac tgcctactat
     5521 ttgatacccc actacctaat tcagctccaa tatcgtcaaa aaccaccaaa tcagttgttt
     5581 taatatcggc tataagcgat ccttcaattt cttttctcag ttcagcattg ttataagaaa
     5641 actttatttg ctctaataac tcttgatagc ttataaaaag tattttcttg tcataatttg
     5701 agcgctcaag tatttcccaa gctgtcgcca ttgacaagtg gctttttccg cttcctgatt
     5761 tccctgatag aatgaaatgt gcaggatggt tcagtaagac atcatttaca aagcttttag
     5821 ctctttctaa agcaattttc gtttcttggt ccactacgtg ataattctcc attttgcatt
     5881 taaacaaagt tttatctgtt aataccgaac cattttgaaa aaaactcaac gctcgtgctt
     5941 ttaagctgtc gttatatatc cgttcggtct gtatatcctc tttcacacgt aacgctttat
     6001 aaccacaact catgcatgtt ggtttacaac gttctgaacc atccttattt ttagctcgcc
     6061 aactatacaa aggttcgcta cattctggac atttcccgct ttgcactaat actcttctta
     6121 ttagtttctc catagcattt gctaggcttt ccatgtgatg catctccttt ttaaattggc
     6181 aagtcgtcat attcactagg attgctgtac tgtagttttt gactttgctt tttatgatta
     6241 ttcttgtctg ctttgatttc gaatttgagc ttctcaaatt tttctctcaa tttcttagca
     6301 cttctaatat ttccaaacca aaattcattt gtaggtagcc aattgatcac atactcaatc
     6361 gcttctatag acgctttatc tctttcttcc atcaacctga ttgtgtctgc ccatttttcg
     6421 atatctactt tgttcatttc ttttggaaaa tcttcagtta aattactttg caatttttta
     6481 gcaaggcgta agtgttcgtc agaatactta cctttctttt cttctttatc tatatctata
     6541 tctttctcta tctctatctc taactctggt gtagttttgt ctggacattt gtccgacact
     6601 tgtcctccag ttattaaatt ccgttttgcc tcttctattt tctttctgta ttctcttttt
     6661 ctatctgctt cagttgagga ttttccaatg aaactttgta tatcagacat ataaattgct
     6721 ccgttatcta atacgtcaat aagctgcaaa tcacggaaaa tttgtaccgc tttttctacg
     6781 actcctacag aatgtcttgt aatagttgcg agcattgtag agttaaatgg aatcctgtca
     6841 ttaaacatca acttaccttc gtgttttaga cttcttaaat aaagtttgag aagaatatta
     6901 gaataaatat agccatctgg catactttct aagagaacca tctcgtcact atcgaaaaaa
     6961 ttctctttta gttttaaata gtagtagcgt ttgttgtcag acaatatttt ttaccctcct
     7021 attctaagtt tcttaattgt ttcctggttt aacttgatcc ctttgatttg atatttattt
     7081 ttgaaattga tcacacctat attgtgtttc tccgtgtgat gaatcctgca gagtgctgca
     7141 aatgtgtact ctgaatgatc aacttctttg cgctttcgtc ttcctagcgc tttgtcaaag
     7201 tgatcgatgt cagctcctgt tttgccacag atgcagcaga ctctttttgt gatgcatttg
     7261 tagaagtaat attcttgatt cgctggtaaa atctcatagc cttctttgaa aggaatatga
     7321 tgttcaaaga tgaaatctaa gatgatattt gctaagacat tagcatcact cacagttgta
     7381 ttcgattcgt ctttgaggct tattttgcgc cctgtgacgc cttcaaaacg gaagtaaaag
     7441 aattccttcc agaagtccgt tggcatgcct gtatcgatga aaatatcgcc tatcagcgca
     7501 tagatgaagt ttcgttgctg cacagtaaat cgacgtggat caataaatcg aacttcaata
     7561 atccgatcgc catcatatcc gtcatacatc gtctttagtc gatcaatgtt cacttcttca
     7621 ttgatcgttg cacctatgtc ttttcctttg aactttttca gaaccgctga atatgaatcg
     7681 atcaatggtt taaacactca tatcacttct cttttgtttc ttctctgtac tgatcttcaa
     7741 tccagttaac gcctcgtttt agaatgccca agtctctctt ggtccattta ctgtcatcag
     7801 cggttataga agccgcatca gtcaatgcaa caattgcttc atcaattgat ttttcgtact
     7861 tgttagcaac cagttgtaaa gcatccaaga atagcttttt gcttctttga gtagctggtt
     7921 caagcatcga gacatcttct ggcatatctt cgccagcaaa tatatatagc cctagcccaa
     7981 acattgctag attttttaca agacagcgca tgatcgtttt gttgatatca aacatagttg
     8041 ctgcttcaac tcgcttttcg atttttccaa caatctcttt tttcttcgtt tcgttattcc
     8101 actgataatc attgacttcg taggtatatg gctcatcttt cattgccttg tttgcaccat
     8161 ccatgactgg taaccacatg tcacgcttta ctccgttgac tgtgatactg gtaaaaacca
     8221 tatagcctgt tttcttatca aagacatacg gcagatatgt ttctggatca tgatagattt
     8281 cataatctac tgcctcacac actttgctaa cttctgccca agcccatgcc cacgaaagat
     8341 aagtgaggtt atttcgtttt tcagtaacat ctttcacatt tattttgtat aaggtattaa
     8401 aaagcgtatt atcacttcta tttttcaaag gttgttcctt ttcactcatc aaattctgcc
     8461 tccatttcag caatgtattt cttacctgat ccgtaataag agatatcaat caagttatct
     8521 ctgtcatact cttctagcgc atcaatcaag ccatcttcga tgacatagat atattcagtt
     8581 tttttggact tcctcgataa atggataaga tagacatgat cccaaatact cacaaaattt
     8641 cccaaatcgt cttgatcaca tgctagttct tcatccgtca aaagattacg tctgattttt
     8701 cgattgcttg tttccttgat attcgatttg ccccaactag gatcagtcaa atattgatct
     8761 agagtggaaa gttctttttt catgtggtaa catctcctta gatgtatttt ctttgtgact
     8821 cattgctttg gtcggctgag tcactttttt atttgttgcc atgctttttg cttatcaata
     8881 tgttgttggc ttaggatgtt tggtttattg tgtctccacc agcgattagc aattattacg
     8941 cctattttta gcgcttcagc tctattcatc ctctaacaac tccatttgct taataattgt
     9001 catcgtcgct gtagaaggca tccaattgtt aataaaatcg ataacatcat cgaactgttt
     9061 tgccttgata cgatttctag ctactgctcc agtgattcgc ttaattccgc cattcaagtc
     9121 tttaaacaat tctgcttttg ctttgctatt taaatgctgc tgattacaaa taactctaat
     9181 tttgttgcga accatattag aaattgttcg gtaatctggt tcagctagaa gttgattgtt
     9241 cttcaaatcg tttaaatcag actcgatagc gtctactctt tcattcgttt cttcgtttgc
     9301 agctagagca agtaatgcca tttctcgttt agttgctgga attgatggca attggtcttt
     9361 taattctttt tccatcttgt tgaaggcctc aatatattga agtttaaaac ttaaagcttt
     9421 cttaccagtg aagcccattg ctaatagaga gaagccgtct ctattcatat aaataattcg
     9481 gtatgattgt ttattttgag gatgaacata agtatcttcc caaaataggt ctgcccaatt
     9541 ttcggcaacc ccctctttta gttcatcaat agccgtcaaa acatgtctgt gctttttatc
     9601 gaagctttct gcaacttgta agctcgtagt cacagcttct ttatttttca aaattactaa
     9661 ttcttgcatt atttcttctc tcctttttga tataattctg gtggggtgaa aacatgagca
     9721 gaaaaattga taatataata ttgttaacaa ctatttttta tttagtaatc ggagcaactc
     9781 tttccttact gtcatttttg tccaacagta gtttgattgt gttaaatcaa aaaagcatat
     9841 taacagaatt tgcccacata gattacttct ctttttttaa aactggacta atatgtttat
     9901 ttctatcttc atttatcctc tatataggaa ctacattttg tctaatggtg cttaatttaa
     9961 aaatgtttat aattgaaaaa tggatagtta ttatcgcaaa gattttctca tcgatatcaa
    10021 ttatcattcc aatgacattg acgttttcta aagagcaatt taacgtagct actacattcg
    10081 tatcttttat agctctattt tcgtttgctg ttcctaaaac ttttcaaagc aaatctagca
    10141 acgcaaaggt taatgtagaa aacactgata gaaaaaatga tgaaagttat taaaaaaaat
    10201 aattctttca tttattgtca aacctttctt atagacatta gactttttta gtcagtccct
    10261 cccgactggc ttttttgttt tgtactcagc ttcatccagc cctataaaaa tccaaaccat
    10321 gtacacaatc gtacctatca acgcttgtct gcttccccag aggcctaaag cgtagatgat
    10381 tagcggtgcg ctgaatacta gtgctctgtt gaatttgccc attaacttgc ctccttcaaa
    10441 acatctgaag gcgataaact ttttacacga tatttgtttg cgtctttcca ctttaaaaac
    10501 caaataaaag tatggtaatg aataaatgtg gttgagtgac ctggacgaag tattccttct
    10561 gcaaattcag gaattgtttc catttccttg cagtattcaa ctaaagtagt ttttgacatg
    10621 ccgtggaact tctccaagat taaactttgt cggtaccagt cgtctggttt tactgccttc
    10681 tcagcagctt ctatcagctc tgaaagtgtt ggttttttca cttattatcc ctcctaaaaa
    10741 ttatcgttcc atactcgatg tttaacattt cttgaagctc tgattttgta agaatgattt
    10801 tatcttccaa cgactttacc tccctctaca attcgtacat agtgataatc gaatctataa
    10861 ttctgtttgc ttctgcagaa gtctttttac cgtttaaaat taaagataag tagcttttgc
    10921 taattccaaa tctttcagca agcatggtgt aagttaagaa ctttgaactt tcgacatatt
    10981 ctttgatttt ttctctatct cgttgagtga tttctgcaat gtcagtcata ctaaaactcc
    11041 tttctaacca atttcctcta aatccatttg agggtaatag ccctctgcga ttaataagtt
    11101 gtaaataaac actcgccctt tctgtgtcca tttggtattc attacaactt tagtgccgcc
    11161 atcggctttc ggtatctcac ttgtgtgcga ttttgtgtat ccttggttca tatgttttcg
    11221 gtaaagtatc cattgtccgc taactttatg ctgaacacct aactcgttta gcaatttgtt
    11281 tagagcaatt gccgacattc cgtaatcagc tgcaatttga gaagtagcta ccgtatctgt
    11341 cgatgaaaga atcgtatcta agtagctaat ctttggttcg tactcggcaa tttgttgttc
    11401 gagtaattgg ttcttttctt ctaaatccgc tgctaaacgc aatgcttgtg caaaactttg
    11461 aggtacgttt gaatagctac ctgtttttct aattgttgga aggacttcac tcgttaccca
    11521 acgtttaaat tttttggcag agggaagttt tgattttaag attaaactgt aaaggcctga
    11581 ctcgttaatc aaaacaactg ctgttccatt gacggtgaac gaatcgttct gcgtcttatc
    11641 ctccaagtcc acatgatctc gaatagcttt ttgcggattc gaatatccta gaacgtctgc
    11701 tacatctttt cctacaaaat atggttcatc atttactaaa atagttcgaa cttcgttttg
    11761 ctcgaaatta aaaatttgtg gtgtattcat atttctcatt cctttctttg gtataatttc
    11821 cttatcagtg tgacaggctg aaataattgt taaggaggtg aaaatttatg aaaccagaat
    11881 ttgtaattac tatgcttgat ggagaaaaaa tcaaaatatt tgccgatact ttggtcgttg
    11941 gatacgatga tgcgtcaaat atcgaagaaa aagatggaat gttctattct tctcaaattt
    12001 acgtgaatac cttgcaaggt gatattgggg tatctactct tgcaacatca agaccgcttg
    12061 taggtcttat cggctttttg tcaaaagcaa cattcttttc tctcggcgat gatatagatt
    12121 cggatgaaac tgtcatctat aaaacatcag ctgttaaaag tatcggtttc aaatagtaat
    12181 tcttgctcgt tgatagcgga agccaacttt tcttccaaca catcggcgag ctttcttttt
    12241 gttggattca tttcaaagtt gatagtcttg agaagcattt ttgcatcctt aactttttgt
    12301 ccttgcaatt ccttgatgat tttatcggct tggctatcaa ttccatgtgt tagatcatct
    12361 atcatttttt gtaccttgat tgtttggctc atttccttgt tcattgttta gcctccttta
    12421 ataaatgatt ttttgtattt tttaatttcc ataaattcct caaattgctc tttggtatta
    12481 ttaccacgac catacatatt gtgaaattct ttatggcaac tgacacaaag tgtaacgccg
    12541 tttgaaatcg ctgcggattt agttgttgca tggctaaatc acgaatcaca agtatctact
    12601 aaaggcgaat caatttcgcc aaaagaaatt gttcaaactt atttagatat tcattatgct
    12661 gttatctatg gtcagcttcc agaagaccgt aaaaacgatg actaaacgtg agctaaaatc
    12721 tctgctatgg ctgcaaccat ggcagagtct tctttatcta ccgcgtgttc catcgccact
    12781 tttgcttgtt tcagtatgtc taatttcaaa tcttcgattt ttgccgagac tgttttttcc
    12841 atattcttct ctcctttctt ttatattcgt aaacaaattt aacaactttt taaaaaactg
    12901 cgttgactaa attaacatac agtgttaaaa tcagaacata gttaaataag acatataaac
    12961 attgatttta aaagctttct tggcggttgg catttattaa tcaatagtgt tttttgttgt
    13021 ctttttagtt gttaaacttg tttacaagaa tgatattaac accttttgtt aaaatagtca
    13081 acgaatttta acaaataaag ttaaatattt tttcttgaac gaaaggaata ttgatatgat
    13141 aacgtttgag agaataaaag agttagcgaa aaaacaggga aaatcattaa ataaagttga
    13201 agaagaccta ggctatggta aaaacgtctt atatagactt aagaactcaa acccctctac
    13261 agaacgtttg caagaaattg ctgactattt cgatgtctct gtagactatc ttctggggcg
    13321 cgaagaaaaa gaaaccccta aacatgtgga tttatcagaa aacgatactg ttttttcttt
    13381 tgatggaaaa gaaatatcta aggagacaat gcgtaaagcg attgcaatcg ctaaagcttt
    13441 agaggaaaat gaatagttgg agtgatgggt tgtatgtatt tgaaattgaa agaaatgttg
    13501 agcgaataca atttgaaagt agtttacatg gaaatgaaag agcctggctt ctattatccg
    13561 aagcctagaa tcattttttt gaatgaaaat ctatatggcg aaactgcaga agcctttcat
    13621 ttatctcatg aacttgcaca tttcagcgcc tctcattttg aattttcagt tttgtacgat
    13681 acttctacaa cttttcactc aaaatttgaa acagaagcag ataaaatagc tattctaatt
    13741 ttattaaata tctatattga gaacgaactg actgatgaat ctcagtttaa cctcgaaaaa
    13801 tttatggaat attattctat tcagaataag ctcagataca cttgttatgc tgtctgccaa
    13861 tgctatttta agaaaaaata ttcttacgca aggcaatatg tatgaataca tcaagaatta
    13921 ttaaaaaaac cgatttcagc aaaacattaa aaaagcccgt gctggcacac ggactcatac
    13981 ctcatttctg agatcgcaaa tatattataa caagaagtga ggaatattta aatggcaaaa
    14041 aaagttatgg gtcaagacgg aaaaatgtat aaagttagta aaccttttta caaaaaagta
    14101 tggttttggg tattagcagt aattttaatt ataattattg gttctgcttt aaatggtgga
    14161 tcagatagta ataaagcaag tgataatggt ggcgaaaaag taactaaatc ttcaacctct
    14221 gcttcatctt ctaaagaaga aaaaagcgat accttctata agattggtga cactgtaaaa
    14281 gttggtgatg ctgaatatac actaaatagt gtagaactaa ctgatgaaag aaatcaattt
    14341 gaagaaaacc aacctgcaca agtagtaaaa attacttata ccgtaaaaaa tgatggcgat
    14401 tcagatatcc ctgtaggtac agatgtggaa gtatatggac cagatgacaa aaaatcagag
    14461 acatatgcca acgaaaatac aatgggatct gttgctccag gaaaacaaat ggatgtaact
    14521 gctcatttca cgttaaacca aaagggagaa atagaaatcc acttctctcc tttagtatca
    14581 tttgaaaaag cagctatttt taaagcaact gtataataaa taaaaaacac gccccaccgt
    14641 ccagagtaag agcgtgcttt tagaaaacaa acctatatag gtctatttgt tatgcctatt
    14701 atagcaaatg ataggagatg ttaaaagtgt gggttgaaca aaccaaagat ggccaattca
    14761 agtttattga aagatatgta gatccttata cagaaaaaac acgaaaaaaa tctacaacac
    14821 ttacaagtaa ttcaccacaa gcgtggaaaa aagctcagaa aattctagat aaaaaaatta
    14881 aagaagcact cgaaaattac aataaatcag atatcacttt tggtgagctg tataaagaat
    14941 ggtatgaata ttataagcag catgttaaac gtactagcta tttgaaggtt ccaatgatga
    15001 tgaaacatgt ttctaagcac ataagcgatg atacaatcgt tagaaacatt gatgagacac
    15061 tcattaataa gatgattgaa gatatgtaca cttttggtga tctctcactg aactacacaa
    15121 agcaaacaaa aacaactcta tccgttatgc taaactatgc aattgataga aaatacattc
    15181 aaagaaaccc tgctctagca gttaaaatcc atcctaaaaa agtggaagaa gaaaaaagaa
    15241 agctttctat ggataaaaaa tatctggaga aagaagaaat tgatcaaata ctgaaacagt
    15301 tatattccaa tcctcgcaga aaactacacg gcataatagc tgaatttcta tatttgactg
    15361 gtttgagata tggggaattg ctggctttgc aaatgaagga ctatggagag ggtaaaattt
    15421 ccattaatgg gaccttagat tacacatctg taaaaatgga taacgccata aaaacaactc
    15481 caaaaaatac ttactcacaa cgtgaagtac aattatccaa tcgtgcaaaa gaattgattg
    15541 aaagtgtgat agctgacaat attcttgcag gtagacccac caatcccgat caatatatat
    15601 ttatatctac aaatggcact ccgcttacgc tgcactcatt taacgctgta ctccataaag
    15661 tagaagaaga gttggaatta gaaaaaaatc tatcatcgca tatatttaga catagccatg
    15721 tttcgctatt atctgaatta ggcgtacctc ttaaagccat tatggagcgt gtaggacatt
    15781 ctgatgcaaa tacaactctg tctatttaca atcacgtaac caaaaaagca aaacaacaag
    15841 taattgataa actaaatagg ctttgatatt tctgcccctt ttttgcccct tttacttaaa
    15901 ataaaacaaa aaaagaaaag agaaccctgt aatataaggg ttctctttta attcctacat
    15961 cataccgccc atcattgatg gatccattgc aggagctgct ggcgctgctg gttctggttt
    16021 atctgcaacg actgcttctg tcgttaataa caaggcagaa acggaagcgg cattttgcaa
    16081 ggcagaacgt gttactttag ttgggtctac gatacctgct tcaaccatgt ttacccattc
    16141 tccagtagca gcattgaaac cagtgcctag ttccacgttc ttcaatttat caacaatcac
    16201 tgatccttca taaccagcgt tttcagcgat ttgacgaatt ggttcttcta aagcacgaac
    16261 aacgatcttg atacctgttg ccacgtctcc ttctgcttct acagcagaaa ctttgctgat
    16321 aacgttcact agagctgtac caccacctga gaccattcct tcttctactg cggcacgtgt
    16381 agcattcaat gcatcttcaa tgcgtaattt taattctttc aattctgttt cagtagctgc
    16441 accaacttta acaacagcta caccacctgc taatttagct aagcgttctt gtaatttttc
    16501 gcggtcaaaa tcagaagttg tttcagcaat ttggtttttg atcaattgca cacgagcttc
    16561 gattgcttct ttttctccag aaccttctac gatcgttgta ttgtctttat ctacaacaac
    16621 tttagaagca tttcctaagt tttcgattgt tgcatctttc aattctaaac ctagatcgtc
    16681 agtaattact gtaccacctg tcaaaatagc gatatcttca agcattgctt tacgacgatc
    16741 gccgaaacca ggagctttta cagctactac gttgaatgtt ccacggattt tgttcaatac
    16801 aagagttggc aatgcttcac catctacatc gtcagcaata atcaacaatg gacgtgattg
    16861 ttgcaagatt tgttctaaca atggcagaat atcttggatg ttagagattt ttttgtctgt
    16921 gatcaagata tatgggtttt ctagaacagc ttccattttg tcgttatctg ttaccatata
    16981 ttgtgataag taaccacgat caaactgcat accttctaca acatctagtt ctgtttcgat
    17041 cccttttgat tcttcgattg tgatgacacc gtcgtttcca actttttcca ttgcatcagc
    17101 aatcaaatgt ccaactttat cagaacccga agaaacagct gctacttgtg caatggcttc
    17161 ttttgaatca acaacagttg agatattatg caattcttcg actgctgctt ttgttgccaa
    17221 ttcgatcccg cgacgaatgc ctagaggatt agcacctgca gttacgtttt ttaaaccttc
    17281 gcgaacgatt gcttgtgtca gaacagttgc tgtcgttgta ccgtctcctg caatatcatt
    17341 tgtttttgat gctacttctg atacaagttt tgcacccatg ttttcaaaat gatcttctaa
    17401 ttcgatttct tttgcgatcg tcacaccatc atttgtgatc aatggagagc cgtaagattt
    17461 ttctagtacg acatttcggc ctttaggtcc taatgttact ttcactgtat ctgctaattt
    17521 atctaccccg cgtaacatag ctgcgcgtgc gtcttctgca aatttcaatt cttttgccat
    17581 gattgattca cctcattgat tatttttgat tattttttta tcttccaaat ttactcaaca
    17641 atcgccatga tatcttttcc tgcgacgatc agatattctt ttccttcgta ttttacttct
    17701 gtaccggcgt atttttcgaa cataacttgg tcgcctgctt ttacagcggc aggaactttt
    17761 tcaccgtttt ctaacaaacg gccttcaccg actgcaacaa ctgtcccagt ttggggtttc
    17821 tctttagcag cagaagctaa aacgattcct ccgacagttt tttcttcttc ttttgcgact
    17881 tcgataatga cgcgatcacc taatggtttt aacacgataa atccctccga taactctttt
    17941 tttaatctgt tagcactctt aaccttcgag tgctaaccta catttttaat aatactcatt
    18001 ctccctcttt tttgcaagct tttaaatcaa agaaaagaaa ttttattctg acagctgctt
    18061 attgaaatta tgatataatt gaaatcaatc gatataagct tgccttgcat gcttgttatc
    18121 ccttaaaagg aggaattaca tgtctttaaa aaaatatagc ttcctcagca ttttttgcta
    18181 tggtctaatt tttatctcac ccttgatcct agcttcgata ggacttgtaa aatctacgtc
    18241 tgaattgatc acagcaactg cagtcatgta tatactaggc gccgttgtcc tagctatttt
    18301 ttattttaag caacgtgaac ccttagcgat cgaatcagcg gtaaaaaaag cttctgctcc
    18361 aaagattgtt atttatggat tggttggaat ctttgtcgca ttgattctgc aaagcatcgc
    18421 tgtcatgtta gaatctgtat tgtttggcaa agcaacccct tccgagaata cacaaaatat
    18481 catccagatg atcatggaag cacccgcttt tattttggcg acaactgttg ctggacccat
    18541 catggaagag ttcgtattcc gccgcagtat actggggatc atcagtcgat attcaaattt
    18601 ttgggtcgga gcagtgatca gctctttgct gtttgcgttt gctcataatg atggtcatct
    18661 gctaatctac tttttcctag gtttcttctt cagcctagag tacaaagcaa ctggtcggat
    18721 ctggacatcg atgatcacac acgtaggaat gaacacatta gttgttcttg ttcaattagc
    18781 tgtccaaaaa gggctagtat aaacatgact ataaatactc ctgtcatcct agattggtga
    18841 ttttcccaat ctaaagcgac aggagtattt ttgtttttta gtcgttcatc ttttctgctg
    18901 ctccatcatt ttttgtctgt ctttcctttt tgcagtttgc agaatctatt tttttcaaaa
    18961 atgggaaata aatgaaaaaa ctaattgaca acacgatacc ttgtaaaatc gctgcaggca
    19021 ctccgcctac taagaaaccc gagaggatcg gcggtgttgt ccaagggact tggactgctg
    19081 taaataaagg aacgaatcca aaatataaag cggaataggt aatcaatcct gaaacgaccg
    19141 gtgcgaaaat aaaaggaaca gccatcatcg ggttcatcac gatcggtgtg gaaaaaataa
    19201 ttgattcatt gatgttgaaa aaggctggta aaagagcaag atttcctaat tctctgtatt
    19261 tcttcgattt cgcaaaaacc gtcataaaaa atacagcccc taacgtcaat ccagcacccg
    19321 taaccgtcat gaactgatcg agaaattgct gagtaacgat atgtccgcca tttgccaccg
    19381 tcaactcttg tcctgaggct aagatttctg catttgctaa tgaattcgct tgcaagacgg
    19441 gactaaccaa cccattgacc atcgcagatc catgaagacc aaataaccat aaaaacggaa
    19501 caaaaaaacc taataaaagc acaccaaaca acgtgtctat gaacgattga atgggaagct
    19561 ggacatatgt ccatactcct tgaacaacag tcattctgaa caaatgttga aaaaccgctg
    19621 aaccgataag cgtaaaagtg actataacaa tgattggaat caatgaagta aaagactgcc
    19681 aaacattttc aggtatcttc tctctttgct tccacccttt cgcaagtctt actaaacgtg
    19741 catagcccca tccgatgatg agcccagttg taactgctcc tagtatccct tcagcacctg
    19801 tccagacagt atctatctga gtatttagtg gctgaataag cagtagataa gcagacaagg
    19861 ctgttatgcc gactggtaag cgatcgatgt cttcttcttt tgcataagcg tatgcaatgg
    19921 caaaaacgat ccaaaaggct atcacatcaa atgtagcctg gtatacttgt gtaaaataca
    19981 tagaaaatcc tgttttgtct atccactgag cgatgtaatc cacaggaaaa tgagcaaata
    20041 agaaaaacag cgagccaaca ataattattg ggatcgtgta agtcattcca ttacgcaaag
    20101 cagttaaggg tctaagattc acaacagatg ttatcattgg taaaaaggca cgatctaacc
    20161 actctttcat ttcttatctc cttcaacttc tatttttatc aatcagtttt cttaatttaa
    20221 ctatacccaa tgatcacgaa ccatgaaagg aatgcgcact gagcttttca aaaatcggat
    20281 tctttgacga atattcagca actgcttaca atggacagga ataaaaaagg aggtttttta
    20341 tgaaaattgc actcattgga gctactggcc atgcaggttc atttatttta gacgaagcat
    20401 tgtccagaga tttagacgtg acggcaatcg tgcgtcatcc agaaaaattg ccatcagatg
    20461 ttccgtttat acaaaaggat ttatttgagt tgacaactac tgatcttgca tcttttgatg
    20521 ttgtcgttga tgctttcaac gctcccaaag gaaaagaaga aatgcatcaa acttctttgt
    20581 cccatttgat tgagatgctt gaaggaaccg atacacgctt aattgtcgtt gggggtgcct
    20641 cttcgttatt cttagataca gaaaagacga ctcgtatgat tgaccaagta cctaaaaatg
    20701 cacccttcta tccaacagct ttcaatatgt acgaaggatt gttaaaattg aaacaatcta
    20761 aaaatctaca ttggacttat atcagtccag cttctttatt tgatccacat ggcaaacgta
    20821 caggtactta tttgttaagt gatgattatt tacaaagaaa cgctgctagc gacagtacga
    20881 tcagcatggc agattacgcg attgcattag tagatgagat actggatgag aaacatgaaa
    20941 agcagcacat cagtgtagtc agtcgataat acggttattt ttttaatatg ctaaaaaaat
    21001 aaaaatagaa gataaaacca accctgattg attttatctt ctgcttttta tatttttatt
    21061 gattgaactg tttaaatcga aaatagctca gttgcttcat ctggatctgt atcatagatt
    21121 tcaaaatcat gtccaacgcc aaaatctttt tctttcaaaa cattttccat tgttaaatga
    21181 gcaagttctt tcatattgtt ttccttgcta agatggccaa gatagattcg tttggtccga
    21241 ttaccgatca catcagtcat gacaagtgca ccgtcttcgt tggaaagatg tcctctatct
    21301 cctaaaatac gctgttttaa attccacgga taaggtccca tgcgtaacat ctcaagatca
    21361 tgattacttt ccatcaaata accatcggca ttttcaatga cacctcgcat ataatcactg
    21421 caatatccgg tgtccgtcaa catgacgaat gaccgatttt ctttatggaa acgataaaat
    21481 tgcggagccg ctgcgtcatg ggagacgccg aaactctcaa tatcgatatc gccgaatgtt
    21541 ctgactttcc ccatctcaaa tagatgtttt tgttccactg gtacatttcc aatcagtggt
    21601 tccatcgctt cccaagtctg ctgattggca aaaacatcca aatgatactt acgagccaag
    21661 acacccacgc catgtatatg atctcgatgt tcatgcgtca caagtattcc atctaattgg
    21721 tccggtgtcc gatcaatttg agccatcaag gaagtgattt ttttaccgct aagtcctgca
    21781 tcgaccaaaa gccgtttttt ttcactttcg atataaagtg aattacccga acttccactt
    21841 gctaggatac tgattttaaa agctggtttt tcttcagcca tttgactcct acttcccttc
    21901 ttactttgta aacttttttc attatactcg cttttttatt gatcttccac ttttggtaca
    21961 gtattgtttg tcacgatcgt attgctgaaa gcgttgacgc tctcaatttg gaccacttta
    22021 tcgcttgttt cgatcgctac atgccaaaca ggaacataca catttttttc ccggactttc
    22081 agaatacagg aataagctag ctgacgccat aaaatttttg atcctcttgg tattttgtta
    22141 ttgatgtaca atgtattgat tgcttcctct tccgtataca gttccgtctt ttcgcgcagc
    22201 tgctcgatat cagataaatg cgtctgcatg tatttcgtga tgctataatc attatcgttt
    22261 ttttctaaag aaagaacgat ttttgctgta tcatcattga atgggatgcc ttcatactct
    22321 tggcttgctt ggatttctag tggttcttct tctaaatgag aaaagttttt cgtgtacaca
    22381 taatcattac cgaataaaat attgtctttg ttagataaaa aatcttccaa ggaactacta
    22441 attttatctg gatcgatcac gttcttttca gcatctgaac tggataaaga tttcgtcaaa
    22501 acatcaccgt ctaaaaacac accacttgcc agcaagccgc ttttaccagc cttgcgataa
    22561 ttcgctaatg aagtgctaag attggtctgc tccgcgctaa gataatagcc ttgcttgttc
    22621 tcagacgaaa tcttccccgt gtaagtgata tcgtcgctag ccagacgttg ttggattgat
    22681 tcagtctgat tagagcgaat gacattgttt tcttggtata ccgcgtcatg ataactgctg
    22741 aataaaaaca cattcaaccc taaaaaagcg acgaaaaata tccattcgat ttttttgaaa
    22801 tccaattaat tcgcctccaa tccaggtaat ttttccagaa ggtcgttagc tgaataccag
    22861 ttatctttat atttcacata ccattcaggt aagagatcaa cgacacgatt cgtttctttg
    22921 acattttgcc atgtatagcc aacgatcact gaaccaatct tgttgctatc tgctccctta
    22981 gcttttaact gctggatgat ttcattcgta cttgcaagtt ctacttcttc gtctgaaggt
    23041 atcggcactt gaatcgtatt caaactggtt tggatattca cttgcacaga accattcgtt
    23101 tcaccgccaa cttccacacc aatctgtcct ctgctgtctg tcccaaaaac cgggaagcct
    23161 tccacgaata tccgataatc gatcgtattg tcactgcggt caaaatatct gaggttccct
    23221 aaagaactgc ctaatttgct aatatagggg aaactttcag aaaatacact agcattttct
    23281 tttttctctg gcagctctcc acgaaaatca actacttgcg tttccgaatg gatagacatt
    23341 gtttcattcc caccgtaaaa aatcaattca ttgctttcat cattattttt cacgctatct
    23401 ggtttctgga aaaaagcatt tctaaaaagt gtatagggtt gctgtgacag gatataacta
    23461 tacttcttca gtttgatcga atgtttcgta gcatattgcg tgtcgatcgt cgatggttct
    23521 gttgtcattt ctgtccattt tgtgtctttt gctgttaatt ctttattgat atctgtccaa
    23581 ttcaacgaaa tatttgcttc atatacgaga tggttcgaat aattcaaaaa tcggattttt
    23641 ttatttcctt gatcgaattg tattctagta aaatacatat tttcgctttc ttttgccaag
    23701 ttcgacacat ctaaatctaa atcaaatgct tccttgtatt ctcttagcaa aaaaggcgca
    23761 ttataggcca actcaaaacc agagttcaga tttttcacct gttcaaactg tgatttgtct
    23821 cctgaaacta cttcagaaag ctttccaaat cttgctttat cgatgatcaa ttgcaatcgg
    23881 tacacgagat tttcactgtt ggtttcttgg atcattcccg aatggtgcca tgtaacatga
    23941 agcggaagaa agacttcgga agtttttcga ttgctttgag actcgatcat ttgagtgttt
    24001 gtctcatcta cgttgattga actttttcct gctgggctca gccagattgc ataagagaag
    24061 tatatgctta acgcaaccat caaaatgagt cctatacgaa cgactttttc agagattctc
    24121 attcccacca ttcctcctca taaggttcat atggcagcga gatataaaaa gtcgaccctt
    24181 ttccttcctt gctctctgcc caaatagcgc ctcgatgcgc cttaatcact tctctagaaa
    24241 tagctaatcc aagtcctgtc ccaccttgtg ctcttgcacg tgctttatct actcgataga
    24301 accgctcgaa cactcggttc agatcttttt taggaatccc caatccttga tcggtgatac
    24361 ttaaaatcac gttattatgc gtttctaata agcgacaagt aatcgttccc ccatctggtg
    24421 aatacttgat cgcgttattc atgatattat cgactacttg gatgatttta tctgtatcta
    24481 cttcgaccca aagatctctt tgcgtaaatt cacgacggat cttataattt ttttcctgat
    24541 ttcccaccat catatcaaac cggtcaagaa caaaattcac taactcgttg aaattgacat
    24601 attctaattg aagctgggta ttacctgtat ccatgcgaga tagatttaag aggtcattga
    24661 tcattcgaat cattcggtct gtttcatcta gcgttacctt caaaaaattt ggtgctactt
    24721 cctcgtcttt ccacgcacct tcgctcaatg cttcgatata actacgcata cttgtcaacg
    24781 gtgtacgaag ttcatgggaa acattagaga cgaattcacg acgttcccgt tctgtttttt
    24841 cttgttctgt cacatcatgc aagacagcta ctaatccgct gataaaacct gattcgcgac
    24901 ggatcataga aaagtctact cgcaagatca tctgatcact ttccaatgta ctggttgaac
    24961 ggtcaagtac catttcgttt ggatcttcta ataatttccg caacgtatat tcttcttcga
    25021 tatctaaaag tgtcaaaatc gattgtccga ttgcttcctc gtttttgata tctagcaagg
    25081 aaacagccat atcattgatc gtaatgactt tacccctgcg atctgtcgca atgacgccgt
    25141 ctgtcatatg ggatagcacg ctatccaaac gattgcgttc agcttccatt gtatcttgag
    25201 cttcttcaat acgttcagct aactgattga aggtatcagc cagctgtcca agttcatctt
    25261 gtccatgcac tttgactttc cgactgtagt ctcctctagc gattcgaatg gcttgttctc
    25321 tcatttcacc gatcggctgt gtaatcgaac gagcaactaa aacagatacg atcattgaaa
    25381 taaatgccgc aattagtgag gcagtaaaga aaatgactgc tgtgttattg atttccgaat
    25441 atttttgttc gatattactt ttgacgtaaa gagccccgat aacggcatcg ccggtcgggg
    25501 acaggatcgg ttgaacattg atattcaccc gtttatcgtc gttatctaaa gcaacataac
    25561 gtttagtcgt gaaatcattg atatcaacat aatcattttt ctttcccaca gcgctttgtt
    25621 cattgacatc ggttgttcct cggatgatcc ctttttcgtc aacgacccgt atttcgatga
    25681 tatcgctagt cgcactgttt tcaataaatc ttttgatatt cgcatttacc tcttcatcat
    25741 ctgcattatc ttttcgattc aattccgggc tgattgttgt tgctaatgat tccaccgttt
    25801 gattcatatc tttaataaat gtattgatcg tggaacgttc taaaccacgt ataaagtagg
    25861 caccaataat ttcgatcgag atcaataaaa tcagaataaa ggtaatagcg atcttaaaat
    25921 tgactgatcg aaaaaagcgg acttttcttt tcatccaatt actcctgttc tgggttacgc
    25981 aaatagtaac cgacaccacg acgtgtcact aaataatttg gatggcttgg attatcttcg
    26041 atcttttcac gcaaacgacg tacagttaca tccactgttc gtacatctcc aaaataatca
    26101 taaccccaaa ccgtttgtaa taaatgttct cttgtcatca cttgtccaag gtgcttcgcc
    26161 aagtaaaaga gtagttcgaa ttcacgatgt gttaactcga ttgtttctcc tcgtttcgtc
    26221 accatgtaag cttctggatg gatcgtcaaa tcaccaatcg tcaattccgc aggtgctgcc
    26281 tcttctggtt ccttcgcagc cgtggcaccg cgacgaagat ttgctttgac acgtgcaact
    26341 aattctcggt tggaaaatgg cttggtcacg taatcatcgg cgcctaactc taagcctagg
    26401 actttatcaa tttcagaatc tttggctgtt accataatga tcggcatatc ataagttttg
    26461 cgtacctcac gagcaacttc taagccgtcc attttaggta gcatcaaatc aagtaaaatc
    26521 aaatcaggtt ctacctcagc aactttttcc aaggcttctt ccccatcata tgcagtataa
    26581 acgtcatagc cttctttggc taaattgaat ttgacgatat ccgaaatcgg cttctcatca
    26641 tcgacaacta aaactttttt cataaagagc cacctcttat atattattgt cataccttct
    26701 cattataccg tatttctgct tttgtttcat ctttgcctat aaaacaaaag agaaaattaa
    26761 aatgaaagtg caaaatactt tattattttt tgttctaact tcaataaaaa aggaaaacac
    26821 tgattttcac ctcagtgttt cctttttttg atttatcctt ctaaaacttg tacaccgaca
    26881 cccaataatc ccggaccagt gtggactact aatgccggag aaatctggcc aaagtagatt
    26941 tggtttgctt gtgggaactc tcttttaagt ctcgcttcca tttcaattgc ttcttctttc
    27001 gcatccccat gggcaacagc taagttgaag acctttgcat taccgatttt ttctttgacg
    27061 taagcaaccg ttttatccaa acttttttta cgtcccctag cttttcctac tgtgtaataa
    27121 atcccttctt cattacatga gatgattggg ttaagcttta aagcggttcc tacaatagaa
    27181 gcaactaaac cgatccgtcc acctttttga agatattcca atgtcgcaac attaaagaaa
    27241 acttttgttc tttcgactaa ctcattcaga ttactgatca gttgatccca ttctactcct
    27301 tcttccagcc attttgctgc ttggatcgca gaaaaacctg caccaatacc aatatttttc
    27361 gtatctagta catatgcttc caattcttct tgctgttgtg caattaaacg aaccacatta
    27421 tatgtcccgc tcaatccact ggaaattgtt accgcaagta ccttttcata accgtctttt
    27481 ttgatttgct caaagatttc tgtgatcgac tcaccatccg gcaaagatgt accagggatt
    27541 tcctctggca aacgttgata gatctcttca ggggtaatgt caattttatc tgtatatacc
    27601 tgatctttat aaataatttt caatgggatc atatacatct cgtatttttt tatcaattct
    27661 tctggaacat ccgtacctga atctactaaa attgcgattt tattgttttt catttgtttt
    27721 ctcctctttt aaatattcgg tttctagaac aatcgttttt tccgcaagaa gtttcattgc
    27781 aaacgataaa gttgccgctc ttacagcaat atattctaca ggggttgcct ggtcgaattt
    27841 ttgcggatga gatttacctt gtgctaattg gctgaccatc cacacagctg cttcttgttc
    27901 atcgcaaaat agattatagg cttcacgaat tcctactgtt tttccttgga acaatatccc
    27961 ttctttgatt tcaggaatag tcaatacttg tttcaacgta gtgattgcaa gtaaaaatgc
    28021 tacgtgttct ttgttatatc tttttttaac tggtgctggt atcaaaccta gtttaacgta
    28081 attgtttacc atagaagagg taagcaatgg atgcttttct ccttgtatca caggtgaaag
    28141 ataacgatca actaacgttc tgacttggtc catataaagt tctaagtcag ggagttcttc
    28201 ccagtgaggc agacggaatg tttctagttc cttcccccac tccattaatt gctgacgcat
    28261 tttttccatc ataaccgctc cttttttcat ttcataaaca tgatatcaga cttatgataa
    28321 acattcaatc tagttgcttt aactaggtga tttgattagc gggattccat gaaaacaaaa
    28381 aacaagaagg ctaagccttc ttgtctttta tcgttaagaa caggagaccc gccggggaga
    28441 cggcgggaaa ggagtaaaaa atgaaaaaag tgttagggtt tgttctcttg caagaacttt
    28501 gtttgttggt atgcttatat aatagcgagc aaatgtgaat aatctatgaa tgatttccta
    28561 taaggaagta aagatttttc tgattttctt taaatgtagt cttgcatttt aaaattctta
    28621 gtgctactat tattaagtac tttttgtacg ggccgttagc tcagttggta gagcagctga
    28681 ctcttaatca gcgggtcgcg ggttcgagcc cctcacggcc cattgggtgc caaacccacg
    28741 gaacaggtaa atgttggtgc gaaagcattt cgaaaacatt tacgctgttc tttttttatt
    28801 tttcaaaata actagggctt tttattttta actcaaagtc cactgtagcc ctttggactt
    28861 tgagttaaaa aagaagcata attatgaaca gtaaagtttc taatataaca ataattcgag
    28921 aagctttgca aaatcatgct gccaatgaac tctctaaaca tataggatta aatctaagta
    28981 ctataaaagg ttaaaaagtg aagaatattt aatagaaaaa ctaaatttac ttgctgcttt
    29041 ccccttttcc attaatacaa caatcagaga gtgtcttttt ttcgaaaaaa ttagaataaa
    29101 taaaagacac gtagtttttt tatctacatg tcttccatcg actacaagtt atcatttctc
    29161 aaaacgtatt tagcttttaa ttgattaatc gtttcacgtt gtctacacat tgcctaatta
    29221 agattttctt attagaagca tcaatcccgc aataatacct aaaactccag gaattaccca
    29281 caataatgtt aaaagaaaaa atggaataat agataaaatg agtaaactaa taccatagac
    29341 cactgttttt tgattttttc ttactaaaaa acctattatg aaaatcatta tcgaaaaaac
    29401 tagggtaatt cctccaaata aaacaacatt cccgcttaga ttgactaaca tatctatatc
    29461 cttactggtt agttctgtag tatttaaagt agttgaatca atagaagata gaaacatacc
    29521 acccatcaat gctaaaagac tacataaaat ccctgttatt ccactaatta aaatcaaaat
    29581 aaactctgtt tttctcttat tcatttaatt ctctccagat taagtgtttt agaattagaa
    29641 attttttgac catagttaat agcttctaat gaacgaataa caaccactga cgtgttagaa
    29701 aaataatccc caatatgttg tttcttgggc gtgaaagcag ccaccaaata cccaatttga
    29761 aatacaaaat tttttaatat aaacctacat atacactcac gaataaagat agtttgccaa
    29821 cttagctctt tttcctcaaa gctcactact cttatcccaa aaatcatttt cccaattgtt
    29881 tgtcctgaat tcagcttagt caaaagtaca aaataggtta aataaatagc taatgacgct
    29941 ataccataaa aagtaataat ggatttgtca gattccagtc ccatgatttt gtaaaagaga
    30001 cctatagtag catgggtgat gatgctaata caaattaaat caataagaaa agcaaaaaat
    30061 cgtaaccaaa atcccgcaaa tacataatta ggcaaagttt caatgccact cttcttattc
    30121 attttatagc cctccatagt aatacattgg ttttggagta tcagaaaatc caagtttttc
    30181 aaaaactgaa attacacgat ctgatgtagt tgcctttagc ccttgccatt cagcaatctt
    30241 attacctaac caagaagaag caaagccagt tgtgtcattt ttatattcta taaccgtcgc
    30301 atcagttaat ttcttctctt tttttaggga atctaatgca tcttcagagt aaccaatttg
    30361 atccaccaac ccattttcta ctgcttggtt accatcataa attcttccat ccgcaagttc
    30421 tttcactgca ttagtatcca tatttcttcc ttttgctaca acattgacaa aacgatcata
    30481 agcactcatc acaaattcct gtataacttt attctcttcc tctgaaggtt tgtgttgagg
    30541 tgacatcata tcttttaatg caccactttt atacgtcgca tcagttacgc caagtttttc
    30601 taataagcca gaataattta aaccagaaat aatgacacca attgatccag ttgttgtttc
    30661 ttccgtagca aatattttat ctgaaccagc agaaatgtag taccctccac ttgccgctgt
    30721 atttttaaat gcagtataga taggaatatc tagcttttta atttttgcca tttctttagc
    30781 aatctcagca ctttcatata ttcctccccc aggtgaattt acttctaata acactccctt
    30841 aaccgctttg tcttcttgaa ttttctttag ctgtgttaaa aaattctgat ggttatattg
    30901 ttccctacta aaaagattgc tttcacctgt atctgcaata actccattga cggatagttt
    30961 gacaatcttt ttatttgatg cgccttcttc taacgtttct tctgtgattt cgttagatcc
    31021 gtaaaaaatc ttatttattc ctgttagggt tgtatttgat gcttcctctt tatcttttcc
    31081 tggaattagc gcgacgataa tggatagtaa caataatccg cacgctactc ccacagcaat
    31141 ccatcttctt ttattcatat aaactcctcc tatattctta gtaaaaataa ttatttttta
    31201 tttagaaaca catcgacaat ttgttgccaa tatgtttttt ctcctacaat taaagacaac
    31261 tctccagtta atccataacg aaacggaaac gattgagttg tttttaacgt tcctttcact
    31321 gcataaaaaa cacctttctc agtggcagta gaattttctg aaatttcatc taaagttccg
    31381 tcgatcgtaa tcggagcccc acctttttga tccaatttaa aatgaacctt catcccttct
    31441 ttaatatagg tactttcatt cgcaggtaaa agtgctgtaa atttcatttt tgatttttcg
    31501 tggatcggat aaatttctgc aagcactgtt cctttggcta gttctgcttg tccctttgtt
    31561 tcttcattta aatgaaccgt tccagataca ggagctttta gtattccttt tgaaagttga
    31621 tcgtccaaac ttttgataac tgactggttc ttctcttgtt tttcatttag ctctgtaact
    31681 gtttgtttta cagttgttat tgcttgttct agctcttgct ttcctttttc cgtttgacta
    31741 attctgtcat tctcagaagt agttggttta actaatttag ctttttctga ctgatactgt
    31801 tctacttctt tttttagttg ctcaatttgt tcatttatgc ttgctgaaat tgtcagtttc
    31861 acttgatttt tttgatcatc agaaacatta tttagttgtt cttgccaatt ctcatagttt
    31921 gccatcattt cttttgaaaa atcttttaat gattgattat tactccaagc tacctgtact
    31981 tgttgccatt cttgtaattt actatctgaa ctctcaattt gtttttctag ttgtcttttt
    32041 gtcttttcgt atacttctaa ttgcttttga tcatttaatt cactttgctt caaagcgtag
    32101 cggagtgatt ctttttctga caacatgctc tttaattgat tactgtagcc aaaactgtca
    32161 tccgttgaaa acaaattttt tcctttactt atactttcaa taaatagctg agccatcttt
    32221 atttgttgag taatacgttg gttttcttgt tctatctgag ccttttcatt ctctattaaa
    32281 gaacaatcca atctaaccaa cacatcgtcc ttatgaacaa attgattttc ttttaggaag
    32341 ttttccatta ttttagcttc taatggcact tgtaacttct ctattttttc ggggttcaat
    32401 tgagccgttg tccgaataac aacctctttt ttagcaaagg ttaaaaacaa tccaataata
    32461 cataaaaaaa gaattacagg gtataacacc caacggtaga agctatgatg ttgtttagta
    32521 tagatactag aatgttcgaa ccaattatta ttctgcataa attgtttccc tctcctagat
    32581 ttcccataat ttttgataga taccatcggc aaaacgaagt tcatcgtgcg ttcctttttc
    32641 taccaaatgc ccttcatgga gaactaaaat ttgatcacat gcttttgcta ttggtaaatg
    32701 atgcgcaata aaaataatcg ttttttcttt taaattgagg agataattca taattgcatg
    32761 ttctaacaag gtatctaatc cactagttgc ttcatctaaa attaatatgt ccggattttt
    32821 taataaagcc cgtgctaagg ctaatcgttg tcgttgccct cctgaaagat tatttccacc
    32881 ttcttccaac aatgtctcgt aacgtaatgg ctgttgatta ataaattcat ttagttggac
    32941 tatctcacaa acttctatta tttgttcgaa acttggtggg ctatctaaac cgaatataag
    33001 attctcaatg attgttccac taaagaaaaa tgactcttga ggcaaatatg tcactcgatc
    33061 gcgtaatatc tgaaaaggaa tgtctaagtg attaatgttt ccataatgga tcgatccttc
    33121 tgatgcttca taaaaacgaa caaataactt tgcaagagtt gattttccag aaccactaac
    33181 tccaactata gccgttttac tgtgcgaagg aattgtacat gaaatttcgt tcaacgttgg
    33241 ggccttcatg ctatacgaga atgaaacgtt ttttacagtg atatcttgtt gaaataattg
    33301 ttcagaaagc atatattcaa aagactggtt cgatttttct gaatcaatcg cgaaaatttc
    33361 atttaaacga ttatttgcaa cttgagccgt ttgcattttc acttgtaaat taataatgtt
    33421 ttgtaaagga tctgtcaaaa atactagtaa agcattgtat gtgataagtt gacctagact
    33481 aattctatta tccataacaa aataagaacc tagccataaa attaatgcac tgctaattaa
    33541 ttgaatcaaa tgtttaattc cttgttgaat attatcaagc gtaaccgtac gaaatgattt
    33601 tttcattaat ttaacaaatt catggtctat acggttatat actttctctt caccgctata
    33661 tgctttaatt gtttctattc ctttaagact ttctatgata ctagaattta cagctgcacc
    33721 ggctgccatt tcttccctgt tcgatttttc atagcttttc acgaaagcga atattgcaac
    33781 tacataaaaa ggcaaagagc atagagtgat taaaaacaac gtactattct gaatagctaa
    33841 cgtaacccca acaagcaaca ccataccaat atctaaaaat attgataacg tagcacttgc
    33901 taaagcatca ataatcttac tggcatcaag aaaacgagaa ataatttccc ctgattttct
    33961 cgtagcaaaa aaattcattg gtaaagttaa cacatgtttg aaatactgaa gcataattgc
    34021 catactcatt cgctgtccta aaataataag aagataacta cgactatatt caaacaatac
    34081 ccgaaataaa tagacagcga tcaagccaat ggaaattata tttaaagttg aacgtgcttg
    34141 attagggatg aaaaaatcaa gaataccttg aaaataatat gagcttccta tgccaaaaaa
    34201 cgtaatgaaa atcgatgcta aaacgatgtg gaatactaat cctttttgtt tccaaattat
    34261 aggcaaaaaa gaacttaatc cagctacttt ttctttaata ggaatataag tttctctagg
    34321 cataggtaat aaaagaatac ctgtccattc tttttgaaac gcttcaatcg tttttctatt
    34381 ttttccatta gcgggatctg caatccatag tacgtttccc ttcgttttat aaattacaac
    34441 gtagtgcata tagctgttat caaccaatat atgtgcaatt aatggtaaga taagatctct
    34501 ttctttccag atctcactat ctgcttgaat agccatacaa tcaaaagaca atttttcaaa
    34561 tgtctttttc aatccaaatg ctgaagtacc ctctaaatca gtcccagata ggtcccgtaa
    34621 tttatgaatc gggatatcag ttttaaaata ttttaaaatc atcgaaaggc aagcaacacc
    34681 acaatctttt tcatcttgtt gctgcacaaa aggaaatgat tttatcactt atctaacaca
    34741 actccttcta aaaaattttt atagaaaaat tctcaatata gctttaatac agtgaaaata
    34801 ttgtctcata attccacaaa aactttgaaa acagttcttg aacactaact ttttcattcc
    34861 tgaatcaaat ttattttgga aattttacta ttcaagaata aacttgataa gtttcaggaa
    34921 gatttttact gttaatcaaa tacgtatgtt acagtagcac cgtaaaaaat attatttaaa
    34981 gaagcgtgtt taaacatgca aaatgtaaag gaactaagta ttgtggaaat gcacaaactg
    35041 ttggtggagg caataatgct tggggaaaat tggggcaagt tgtaggtgga cttaccacag
    35101 gggcagtagg tggtgcaggt ttaggaacag caatttgcgg accagcttgc ggtgttgttg
    35161 gagggttata tggagctgtc gctggaggtg ctgcagctgg ctgggatgct cgaaaaaaat
    35221 aaaaaaggag aataagtagt atgcatatta aaaacacaaa aacaacattt atattatctt
    35281 cagaagagtt gaaaaatatt caaggtggga gtgccgtggg agttttaggc actacttttt
    35341 ctggggcaac agcaggagta aaactttgtt cagccggagg accttatgca atagctgctt
    35401 gtggtgtagg tggagcttta ttaggtgctg gattcagcat gtggaccggt gcgtaaacaa
    35461 ttaaaaaata tcaaacctca agattggttt gtgtcgatta cgaacatagg tatgttcttt
    35521 atcttttcaa aagtttggaa tggacagaac tttttactaa agcttcttgt gctagttttt
    35581 ataattatat taaattttta tcttttatta aagtcagata aaaattcttt ggaaatgtaa
    35641 tggtagagat atttttacaa aaggacttgc agcgctgtag ttggtgctgc aggaggacct
    35701 atttcggccg ttacaggagg tattggtaat gtacttgtcg gatgtgcatt aaagcctgtt
    35761 cctgcaagtt aaatttataa aaacaggaaa gtaattatct caaatcctat caagtacaat
    35821 cataggattg cacttgacag gacaaatttt ttaactaaaa aatgaaaaac actttctaaa
    35881 aattagtaga atttgccaaa tctttcgcat cttccaccat acatttaatt ttaattcccc
    35941 tttatggtac ttaataaaaa caagaaaaga actattcatt tggccctttt ttggttccag
    36001 accatagaaa tattcctcca gtaactaata ttgctgttat gcacgtaact aataacagct
    36061 ataaaaattg gtacaacttt aataggattc agaaaaattt gcactagtga aggaatctat
    36121 tttattagaa aaatgcaatc tccctaaaga aaaaaccact aaacagtgct ttctttcaac
    36181 ttctccttaa ttttttgtgc tttccctaaa gtaaagtttc tggccaactc tgaatcaaaa
    36241 tatagtgaac gttttttaaa atctatttct ttaacgttaa agatatttac taaacacgct
    36301 cgactaattc ttgttaacat aggatatttc ttttcaagct cactaattct tccataaaat
    36361 tcgtactgcc catctttagt acacaatgat aatctatgtg gtaattttga agcttctaca
    36421 aaataaatgt catttatatc aaaagtaaat gtttgagaac ctatggaaaa aacaaatgct
    36481 tgattcgtaa cctgttttgt tgcatctatc ctttcttgcg ctaataacaa taactcaaca
    36541 atctcgtttc gatactcatc tagtgtttga tcttttgtta caaatcctaa cgtttcaact
    36601 cttcttttta ttgttacggg taacatctca tcatgagtag ttgtaaaaat gatttttgct
    36661 tgaacatcat attttctgat tacttctgct aattctatac cgttaacttc atgatttaaa
    36721 tcaatatcta agaaatatat tccttgcttt ggtcggaatt gtttgaggta ttttttaact
    36781 tctaacggac tttgtgtttt caatactatc ttaaatactt tatcgtgaaa aagaatgaaa
    36841 ttatcaataa ttcgttctaa ctgatttaat tgtataattt gatcttcaca taatattatt
    36901 ggataactca taaatcctcc ttccctcaaa acaacaaaat aacttgagta gtaaattgat
    36961 acggatcgtt ttgatagttc acaaacatat tgggattctt tttattgatt tcctctatac
    37021 tagataaacc taacccttga tgtccctttt ttgttgttat tccttttttc attagagtat
    37081 ctatagagag tagtatctct ctacaactat tcgatatcga aatttctatc tgtttatcat
    37141 ctcggtaaat agctagagac agttctctat cttgactctc tatagatgct tcaattgcat
    37201 tatcgagaat aattccaagc accctaatac agtcaaatat tggaacagga acttcaataa
    37261 tagtacttgg acattcgaat ttacaacaaa tcttattgtt atttgcttgg tatagcttcg
    37321 ctatcaacaa acttttcaaa tattcatttt ttatattttt taaataacga tattcaaact
    37381 tattggttag ataagaatta gaatagatct ctaattcttt tatttctttt tccaatatcg
    37441 aatcatggtt ttgattagcg atttctttta aactcagcaa taaattttta tagtcatgtc
    37501 taaatctggc aaatttttct tgatcttttt ccagtgaatc agtatatttt tttagataaa
    37561 ccaattcttt tcttttcaat tgctgttcat attgttctcg ttgcctaata gttattctaa
    37621 taaataaaaa tagaacaaca aacatttgaa tgattaaaaa tattaagaca ccaaacacaa
    37681 aatgatcaaa tacttgatat tgatgagcaa cataagaaac aaataaacca attgtaagta
    37741 aataaatcat gaatatagca gtaagtttag aactggactg ttcaacaatc ctatttatag
    37801 ctaattttct atataaccaa ataaacatca gcaaaaacaa agaatcaagc attatctgga
    37861 atactacata accataccct tttatccctt caaatgaaaa catatacgtc ataaccatgg
    37921 aagtaataat agatctgaaa tcatcaataa gcatacataa tagtaattta tttaaaagca
    37981 ctatattagt tttcttcttt tcctttaata taaaataact tccgattata ggtatagctg
    38041 cggaaacatc agtaaataat tcaacaaaaa aagtgagtgg tatcaataaa catacaaaaa
    38101 gatattttct tttgttaaga tcagtattag tcatataaaa taagagaaaa aagaaaaagt
    38161 ttcccacgaa cattcttaat agataagctt ttgtatcgat agtaatcaag agatcccctc
    38221 ctgattttag gatatcataa aaaaaatttt agttacactt tttaaataat gaaaaaacac
    38281 attccactaa atttgatgcc ggttttcctt gaggttttgt tccagcacct cctttaattt
    38341 ttttaagctc ttgatctgaa cattgtttag catttagtct atttttttct tccattacga
    38401 ttccccctac aaactataaa tacttttatg tcactgattc aatataccta tttttctaat
    38461 caaaaaattt tgagacatat ttaatattat aagtatcatt aaaattgaga tttatctcca
    38521 taatctgctc gatataaacc atttattcca gcagttcttc caatttcact caaatttctt
    38581 attaattcct cttgatattc agtgaatctt attttattag tataagcagt aaaatataga
    38641 taattcacca atctatttat taaaggaccg ggatctaatt catatttttg tttttctaat
    38701 tttaaatata ccttttgtaa aacctcaaga atatcagaat atttaggatc tttacttata
    38761 gatatatcat tatataattc atgaacaatt tgcttagcat tttttttcat tttagcactt
    38821 ccctggaatt gctccaccta aaaaaccacc tatagacatt cctgcaatac aagtagttgc
    38881 cttggcccaa tcgaccgtac atttattttt agtgcaatac actccatttc cataatattt
    38941 tccactatga gtggtacccc catagataag ttgtgtctct ttaatagaca aaatttttaa
    39001 atgtttcata atctaatcac ccctaaatta atgtttttag actattattc taacattcat
    39061 taaatttcaa aaaacaattc cttcttgaaa cgtagcaaaa taattcctga ataagaattt
    39121 aatcactttt aagtatataa actatgtata ttctttaata ttttttgaga atgcacttcg
    39181 tacataataa actttaatca cattagtctt tcatacctac gatcgatctc tttgactcgc
    39241 acccataaat tcataatagt ttgtcggcgt ctttggacgt ttcgaagatg agctacgcat
    39301 tctctttttt tatagacaaa aaagatagag acgaacatgg agcttccaaa tttggatatt
    39361 tgatccaatt ttggaagctc catttatttc gtgtctgtct ttttattttt tccagctttc
    39421 gactaattct tggttctctt tgatccagtc ttttgctgct tgctgtggat cttttccatt
    39481 gttgatttcc aacataactt tttccatatc tttttctgac caatggaaat tgtctaatac
    39541 tttgtaagct tctggctggt cttctttcaa tccttttcga accatcgtat ggatctgctc
    39601 ttcgcttccc attccgtttt caggatcttc taagtatttc agatcatatt tggcaaacat
    39661 ccaatgaggt gtccatcctg taactacaat tggttcgtgt tttttgatcg cttgacctag
    39721 tgcaacggtc attgctcctg aagaagatgt ctctactttc cagtctttca agttgtcata
    39781 tttttggatc gtgttttcag cagccgtaac tacaccagct cctggctcga ttcctatgat
    39841 tttcttacct gcctgatcgg ttaactcatc gatcgaattt acatccatgt aggctggcac
    39901 tgctaaacca acttttgctc ctgtcaaatt ggcacctagg tcttcgactt gatctttata
    39961 ttgtgcatat tgtgaaccat gagttttagg tagccaagct gaaaccatgg catctgactc
    40021 gccatttgaa acagatttcc acatgattga attatctaat ggcgtcatcg ttacatcata
    40081 gcccatttgt ttcaatactt caccgactac atttgttgaa gcaacttctg tatcccattc
    40141 aacataagat aagttgatac gttttgtttc tttggcagat gaaaaactcc ctataccaat
    40201 cgcacctaag atcactacta ctacagcacc aatgatcagt ccttgacgtt ttttactttt
    40261 ctgtgttgtt gctcctgcag cttttttatt gtttggctgg ttcaaatgct gtgtaaaacg
    40321 gtcaatgatg attgctaaga taactaatgc aaccccgttg acaaatccat tcccgacttg
    40381 tgctctttgc aatgctgata atacgccgcg tcctaagccg ggtgcaccga tcatagaggc
    40441 aataacgacc attgaaagtg acagcattgt tgtttgattg atccctgcca tgatcgtact
    40501 tttagctaaa ggcaattcta gtttgaatag tttttgacga cttgtgctcc cgaatgaatc
    40561 agaagcttct actaattctt taggaacttg tcgaatccct aaattcgtaa aacgaacggt
    40621 tggtggcaga gcaaagatga ctgaggcaaa tacccctgga accatcccga taccgaaaaa
    40681 tgcaactgct ggaatcaaat aaacgaatcc tggcattgtc tgcataaagt caaggatcgg
    40741 tttgataata ctttgggctt tactgctttt tgccatcaag atccctaatg gtaccccaat
    40801 gatgatcgag atcacactag ataaaagaac aagtgtgaca gtattcatca aatcattcca
    40861 tagaccttgg ttataaataa accatagacc gattaatgtg aacaacgtaa gtcctggacg
    40921 tttcttagaa ataaagaaag ctgctaccgt caataacaag ataaacaaag gagctggaat
    40981 cactaacagt aaatttgtaa tccccgacat cactgcctgt ccaatcgttt gtaaaaatga
    41041 aaataggcca gaaaaagttg tcgtaaacca ttctgtgata ttttctaccc agtttgccac
    41101 tggtaattga tagttcaata gattattcat gttcactcac ctcgcttgtt tctgctaatg
    41161 cttcaatcac actacctcgg atgacgacac cttttaattt tccatcctct acaactgcaa
    41221 gtggagtcgg tgagtcataa ataatattga aaatatcact taccaccatg tctttcccaa
    41281 tcaccgtcac attttcatct aggaagtcga tcaatggacg tttttgcttc ctagcttcta
    41341 acgcttgatc tgcagtgatg atccctttca ggtgtctctt tctgtcaaca gccatcagca
    41401 tgctgacttc ttcattacgc atccttgtca atgcaacgtt tggtccatca gattcgatat
    41461 tcgtcgtcaa tgcaggtacc atgatgtttt gagccgtaag cactttggaa cgatcgactt
    41521 cttccacaaa ttcacgtaca taatcatttg ctggattggt caatatttct tcacctgttc
    41581 cgatctgcat gatttcgccg tctttcatca aggcgattct gtccccaatc cgtaaagctt
    41641 cattcaaatc atgggtaatg aaaataatcg ttttttgaac attggcttgc aggtccagta
    41701 attcgtcttg catttctcgc cggatcagcg gatcaagagc cgagaacgct tcgtccatca
    41761 gcaagatctc aggatcattt gctaaagctc tggctaggcc aacccgttgt tgcatcccac
    41821 cagataactg actaggatat tggtctttaa atgaaagcaa actagaattt tctaatgctt
    41881 tttctgcttt ttcttgtcgt tcttctttag gtacaccacg gacttctaac ccgtattctg
    41941 tattttccaa gatcgttcga tgtggaaaca gaccgaagtt ttggaaaacc atattgattt
    42001 tatgacgacg gacttctcgc aattcttctt tgcttaactt cgatacatct tctccatcaa
    42061 tatagatact gcccgaagtt ggctcaatca gacgattcaa tagacggatc aatgtggatt
    42121 tcccactccc ggaaagcccc atgatcacga agatttctcc ttcttttacg tcaaaattca
    42181 cgtcatacac accaaccgtt gcaccggttt tctttaaaat ctccgttttc ggctggtgat
    42241 cattcatcat atctaaagcg gcttgtgtct ttttaccaaa tatctttgtt aaatgtttta
    42301 cttctacttt taccaaacaa attctccttt tttatgtaaa ttcatttttc tttctgaaaa
    42361 aagtgaccac actatgttaa catcatgtag tcactttgtc aaaaatgaaa gaaatttgct
    42421 tgtccaaact gaaaaaaact tggctaaatc tttgtaaata aaaggtttag ccaagttaat
    42481 atttttttaa tatttcacac aatcattctg caagctgatg ctccgggtaa aaaaagtttg
    42541 tcatacgctg tagtgtatat tcatttccaa taaaatgaac gatgtcccct gccgtaaatt
    42601 tagcataggg gccaggtgaa acaagcagtt cttcattatg agaaattgcg ataactgtgg
    42661 cgccagtcgc ctgccagata ttcaactcgc taattgaacg gtccagatgc attgcttttt
    42721 ctgataaaga taattcaaac ggaagtaaag gattcatctt atgtattcgc ttcgtttgat
    42781 tgaccagctg atccaataat tgagaaaaat gattcagctc atcttgttgc ttctccacac
    42841 ttgccatgat ttctgctttt gtatcttgga tggattgtac atcttgatat tgcaatagga
    42901 aatcttttgc tttttccttc gaagcaacaa atgccccact tccatgccgt acttccatga
    42961 ttccaagatc taccagcaca ttgatagcct tgcgggtagt ctcaggagaa gcattgtacg
    43021 tactggcaag tgttgagcgg gcatggatct tctcacccac tttatatcgg ttttcaacga
    43081 tacgttcggc taaatcaaca gcaatctgct ggtagcgcgg gcggacgatt tttttctttc
    43141 cagacatttt ctttcctctt tcttttttta ctttccctca tcttactatg ctctagcaaa
    43201 ataagcaaaa aaggggagaa tagcctcttg caacgactga tcatcgcttg atctgttcct
    43261 tttttactgg gcaagctgtt tgacagtcat cacaattctt accggatttt aaacgagtat
    43321 agacaattgc gcctgcactt ccaaagatta acacacttaa taagaatgtc gccatcctat
    43381 tcctctcctt ctaatgacaa tatagtataa aactggttct tggattttgg ctgacggaac
    43441 aaaacataaa cgagtcctat catcagtaaa atagcaagat acgtccctaa cgctacctgt
    43501 ccaccctcca ataagtgtcc caactgataa atcacaaaac taactaaata agctaaaccg
    43561 cattgatagc ctatggcgat ccaagtccat ttcttggcat tcatttcccg atggatagcc
    43621 ccaattgccg caaaacaagg cgcacaaagt aaattgaagg ctaacaatga ataagctgct
    43681 gcgggagtat atgtgtgttg tagcacttgc cagatttctc tgccattttc ggatacttcc
    43741 gcatgaccaa acaaaatacc aaatgtgcca ataatatttt ctttagcgac caatcctgta
    43801 atcgctgcga ctgttccttg ccagtttccc caaccaagcg gctgaaaaac aactgccagg
    43861 attcgcccga aaaaggctaa gatactttgg tcttcagaaa caggttgagc ataaaaatta
    43921 taagaagagc tgaaccagat cacgatacta gaaacaaaga taatcgttcc tgctttttta
    43981 acaaaagact tgctgcggtc ataggtttgt cttaggaccg ctgaccattg aggaaaatga
    44041 tatgcgggca attccatgat aaaaggagct gtatctccag caaacaaacg tgtttttttc
    44101 aagctgattc cagagaaaat aattgcagtc ataccaagaa aataggcaga aggagctacc
    44161 caagattgat gaggaaaaaa ggcccctgct actaaggcaa taatcggcaa ctttgcagaa
    44221 caaggcatga aggttgtgac catgatcgtc aaacgacgat cttgctcgtt ttcaatcgtg
    44281 cgactggcca tgacgcctgg cactccacat cctgtagcaa tcagcatagg aatgaaggat
    44341 tttcctgaaa gaccgaattt cctgaaaagt cgatccatga caaaagcgat cctcgccata
    44401 tatccgcagt cttccagaaa gctcaagcat aaaaacaata taatcaattg cggtagaaat
    44461 cctaacactg ctcccacgcc tgcgatgatg ccgttcaaga tcagctcctg catccatccc
    44521 gctacttgcc attcagctaa caatctgcca acatgttctg gtaaccatgt accaaacaat
    44581 gtgtcattga tccaatctgt ccccattgtt cctactgttt gaatagccag ataatagatc
    44641 agccacatca caaatgcgaa gatcggcaag gctaaccaac gattcgttgc aatctgatcg
    44701 attttgtcac tcatcgataa ttggaaagaa tcatttgaca caacacagag tgtacatagt
    44761 tgggtaataa attcataacg ttcattgacc agaatcgtct cactatcgtc gtccaatagt
    44821 ttctctgtta actggatcag ttgctcgatc tctttttgct gagaaactgc tatctcgtaa
    44881 tcctctctta ccttctgatc tcgttcaaaa tatttcattg cataccagcg tttcttgccg
    44941 ctttgttctc ctagtacatc ttcaatttca tgtaaagctg cttctaaacg tggatcatat
    45001 gtacagggaa caggaataga aggccgcttt tttgcagact cctgaatctt ttcgattagt
    45061 ttttcgattc cttgcttttt caatacgctg attggtaaaa ctggtacacc aagaccatag
    45121 gaaagctttt ctagattgat tttttttcct tcttttttga tgacatccat catattcaga
    45181 ccaatgatca taggaatgtc taaatccaat aactgcgtag ttaaataaag atttcgttct
    45241 aaattggtag catcaataat gttgatgatc agttcaggct gttcctgaac caaataatct
    45301 cttgcaatca cttcttctgg tgtataagga gacaaagaat agatgccggg taggtcctga
    45361 atatgaatgt tcggattttt tttcaacgat ccttcttttt tttctactgt tacgcccggc
    45421 caattcccta catattgatt cgaaccagtc aagagattga acaagctagt tttcccgctg
    45481 tttggatttc cgactaacgc gatattcatt ctttttcctc cctttgtatc aagattagtt
    45541 cggcctctga ctttcgtaac gtcagttcat accctcgcac tgtcagttcg attggatctc
    45601 ccagaggggc tagttttcgg ataactattt ttacatttcg cgtcaatccc atatccatta
    45661 accgtcgctt cactgcgcct tgtccgtgga ttgctacgac gatcccagtc tctcctgctt
    45721 ttaattgatc aagagaagtc cagctttcag aggaagcagt ctttttattg acaaagattt
    45781 gacctagtat ttcccgactt actgccactc gatgactttt taccagtaaa atggcattgt
    45841 tgcctgataa attgacgacg acgattttac ttccggcaac gatcccgata ttttgcaaat
    45901 ggcgttttgt tttttcttct gtttcgattc gttcgacttg ataaacgaaa ttctgctttg
    45961 cctgcgctaa ggtctgcata ttgattcctc tcttgtgaaa taaatcatgt attaaaatca
    46021 ttcattatat gttctaattt tcttacgtgt tacgcaaata aatgagaatc attctcacat
    46081 agaatactct cggtaattga gaatgtcaat tatacttgtg atattatgag cgaatcttta
    46141 gtattgatag ataaaaatga gaaaaaaata tttcttcata gttttccaca attttttctc
    46201 tattaaattt gctattttcc cacacgatac ttgttttcag ctcttttttc aaaaacacaa
    46261 aacttagtat tccacagttt ccacaacaca atatgtagtg tttgttgttt gactttttta
    46321 ctaagagttt tatactatct attatagata ataagaatgt gttagaggag gcactcacca
    46381 tgaacgtaaa aatcttttct aaaaataatt gtatgcaatg taagatggtc aaacggtttt
    46441 taacagaaaa tcaaattgct tttgaagaag tcaatatcga tgaacagcct gaagcagtag
    46501 actggttgaa agcacaagga ttccaaagtg ttcctgtcat tacttctgat gcagaaacag
    46561 ttatcggatt ccgtcctgat cagttgcgta aacttgccag ctaacatgac taaaagaatc
    46621 aaaacgtgat acatggattt gaagggcttg agacagcacc agtttttgtc gcaaacttcc
    46681 aaatcctttt ttaaagctta aaaacaatgc aatgatttgc aatcaagcat catcaaatac
    46741 gaaatgaagg ttgggcgtac gtatgagtct taaaaattta caagatgtca gttatttcaa
    46801 gctgaataat gaaatcaatc ggccagtcaa tggtcaaatc cctttgaata aggataaaga
    46861 agctttagtt gccttttttg aggaaaatgt caaaccaaat acgatgactt ttctatctat
    46921 tatggaaaaa atcaattact tgatcgatca agaatatata gaagcagaat tcattcaatt
    46981 gtattcacca tcatttattg aaaagctata tcaatttttg gacgagcaac atttttcttt
    47041 caaatctttt atggctgctt acaaatttta ttctcaatat gcgttgaaaa ccaacgacgg
    47101 ttccgcttat ctggaaactt atgaagatcg agtagccttc aatgcgcttt actttgcgaa
    47161 cggggatgaa gaattagcac ttgctcttgc agacgaaatg atccatcaac gatatcagcc
    47221 agctacacct tctttcttga atgctggacg taaacgtcgg ggcgaattgg tgtcttgttt
    47281 cttgactcaa gtcactgacg atatgaactc tatcgggcgc tcaatcaact ctgctttgca
    47341 attgtcccgt attggtggcg gcgtagggat tactttatca aatcttcgtg aagccggcgc
    47401 tcctatcaaa ggatatgagg gtgctgcaag tggtgtcgtt ccagtcatga aattattcga
    47461 agatagtttc agctattcta atcaattagg tcagcgtcaa ggagctggcg tggtttattt
    47521 gaacgttttc catccagaca ttattgcttt cctttcagca aaaaaagaaa atgcagatga
    47581 aaagattcgc gtaaaaactc tttctcttgg cgtgatcgta cctgataaat tttatgaatt
    47641 gacacgtaaa aacgaagata tgtatttatt tagtccatat agtgtcgaaa aagaatatgg
    47701 tgtcccattc tcttatgtaa atattacagc tgagtatgat catctagttg caaatccaaa
    47761 cattcgcaaa caaaaaatca aagcgcgtga tcttgaaaat gaaatctcaa aattacaaca
    47821 agaatctggc tatccttacg taatcaatat tgatacagcg aaccgcgaga atccaatcga
    47881 tggcaagatc atcatgagta atttatgttc agagatttta caagttcaaa cgccttctgt
    47941 gattaacggc aaacaggaat atgaagtatt aggaacggat atctcatgta acttaggctc
    48001 gacaaatatc gtgaatttga tgcaaagccc taactttggt caatctgtgc gtacgatgac
    48061 tcgtgcattg acatttatta cagatgcatc tgatatcgat gtcgtaccac cgatccaaaa
    48121 cggaaataag ctgaatcata cgattggatt aggtgccatg ggcttacaca cttatcttgc
    48181 aaaagaacaa atggaatatg gctcagagga ttcattagac tttacaaata tttacttcat
    48241 gctgttgaat tattggacac ttgttgaaag caacaatatc gctcgtgaaa gaaaacaagt
    48301 tttccataat tttgaaaaat cagcttatgc tgacggcact tatttcgaaa aatacgtaac
    48361 tggagaattc cagccaaaat cagaaaaagt caaagcattg tttgaaggca tttttatccc
    48421 aactgctgaa gattggaatg ctttgaaaca agcagtaatg aaagatggac tgtatcatca
    48481 aaatcgcttg gcagtagcac caaatggctc aatttcatat atcaacgata cgagtgcaag
    48541 tattcatcct atcactcgca tgatcgaaga acgccaagag aagaaaatcg gtaaaattta
    48601 ttacccagcg ccttatctat ccaatgagac gattccgtat tacacttctg cttatgatat
    48661 ggacatgcgt aaagtaatcg atgtttatgc aatggcacaa caacacgtcg atcaaggcat
    48721 gagtttgact ttattcatgc gttctgaaat cccagaaggc atttatgaat ggaagacaac
    48781 aacgaagcaa acgacacgtg atttgaatat tttaagacat tacgctttcc acaaaggaat
    48841 caaatccatt tattacgtac gtacctttac tgatgatgca gaagaaatcg gaagcaatca
    48901 atgtgaaagc tgcgtgatct aatatcatag atagattcgc ttattcatat tttaattaaa
    48961 ggagcattct catgtcagaa acatattatg aagcaataaa ctggaatgaa attgaagata
    49021 tcattgataa atccacttgg gagaagctga cagagcaatt ttggctagat acacgtatcc
    49081 cactttcaaa tgacctagat gattggcgta cattgtctca attggaaaaa gatacagtag
    49141 gacatgtatt tggcggtttg acactgctag atactgtcca atctgaaagt ggcatggatc
    49201 agttgcgtaa agatgtccgc actccccatg aagaagccgt tttgaacaat attcaattca
    49261 tggaatccgt tcatgccaaa agttattctt ctatttttag tacactgaat acgaaaaaag
    49321 aaatcgaaga aatttttgac tggacaaata cgaatcctta tctgcaaaaa aaagctgagc
    49381 gtatcaatga aatctacaaa cacggtacac cgctagaaaa gaaaattgcc agcgtctttt
    49441 tagaaacatt cttgttctat tcaggttttt atactcctct ttattattta ggaaacaaca
    49501 aattggctaa cgtagcagag atcatcaaac taatcatccg agatgaatct gtacatggaa
    49561 cctacatcgg ttacaaattc caattaggat tcaacgagtt acctgaagca gaacaagaaa
    49621 cgttaaaaga ctggatgtac aatcttcttt atgagcttta cgaaaacgaa gaacgttata
    49681 cagaagaatt atacgatcca atcggctgga cagaagaagt caagacattc ctacgctata
    49741 atgccaacaa agcattgatg aacctaggga tggatccact ctttccagat actgccaatg
    49801 atgtcaaccc aatcgtaatg aacgggattt caacaggcac aagcaaccat gacttcttct
    49861 cacaagtcgg aaacggctat ttgttaggtc atgtagaagc gatgaaagac gacgattatt
    49921 tgattggatt ggaataagga tttattttaa ttcaaaaatt tttcgaaaaa taaaaagagt
    49981 ttagcgtaca gatattttaa atgtacactg aactcttttt tatgcttatt cacttgtttc
    50041 ttccagcact tttggactgt ctaacttttc cgaaacatgt tccattcttc tcaataaata
    50101 gattttccgg atatttaata ttatcgtctt aatcactgca tagacaggta tgcaaatcag
    50161 catgcctaat attcctgcga cacttcctgc tccaatcaat accaagatga tcgtcaaagg
    50221 atggatattc attgatttcc caaataacaa cggcttgatc aaatttccat ctaattgttg
    50281 gatcactaaa atcgacaacg ccatatacaa agcttgaaat ggagagataa acaaaccgac
    50341 aatgattgct ggtaccgctc caataaaagg gccgacatac gggataatat tcgtgattcc
    50401 gcaaatgacc gcaagcaaca agctataagg ctgatcgaat attctcattg ccaaaaagct
    50461 cattacacca ataatcaaag catctaagat cgtactgctg atataggcag ataatgtttc
    50521 gtttaattct tttaccgttt ggcgtaactc tttacgaatc gctttcggaa agaagtgaga
    50581 caacgcatca ataaatttgt gcccatcctt gaacataaat agcaaaataa atggaacggt
    50641 aaataacaaa ataaaaaatt gcatcataaa tgaaatgatt tttgagacac ttgcagataa
    50701 actgactaat atgatattga acaaattact aagagataaa tttgctgatg ctaattgttc
    50761 ttccaaattg aaatttttaa actcttcccg ctgcgccaat tcatttaacc atttgcttgt
    50821 ttcatctgca tacattggca agctctgggt caattgaatt gtctgttcca ttaactgagg
    50881 cactacattc atgacagtta aaacaactaa aatgattacg accaaaaacg tcaataaaaa
    50941 accgaacact ctcgggatcc gatgcttttc gagaaaaaca acgattggat cgaacatata
    51001 atagataaaa ccagcaacaa gcaatggtaa aaaaactgcc gaaagcattt tcaatattgg
    51061 actaaaaata ttcggcattt gtaaaataaa gtacacgccg atgatcgtga gtactagctc
    51121 cactgtccag aaaaataatt ttgattgttt aaaacgtgat tgcatacatc tcctccaagg
    51181 tcctttgata cttctattct atcatttaac aaagagttac gcgctgagat tttcatttgc
    51241 ttaaaaaaaa caaaaaaaat aaacatattt taatgagtag acgagtactt aaacaaaaac
    51301 acggtttgga gtagtgacaa aaattatact gcagtccctt tttccaaata aacggtgttc
    51361 aaaagcttgc atcttcgtaa taagcccagc caaacgaaaa atataaggaa ctatttttat
    51421 ttggctgggc ttattacttg atgtaggaca tctattttac aacctcagat catttattgc
    51481 gcaatactga ctaaatgcaa ctttgtgata tttttgtgta cggacaactc ctcgatcaca
    51541 tcggcataag tgagcccttt tggaagatca atcgtataga tatttttgta cactcggtag
    51601 tcatcaacga attttacgtc aaaattcaca tcttcgatta cgatattttt ctcttcaaaa
    51661 taatcggtaa gaaaatcttt ggtttctttt ctatggataa attggatttc taacttttta
    51721 gtcgtaggta catggatcac gcgtttcact actgtgagtg caatagcaat cccgataaaa
    51781 ctgatgatcg caatggaata gtaacccatg ccgatggcga tccctaatcc agcaattgcc
    51841 cataaagaag cggcagtcgt aagtcccgtc accgattgtt tcgtgacgat gatcgttccc
    51901 gcgcctaaga aaccgacacc actcaccact tgagcaatca gccttgcttc atctgaacga
    51961 atcgttccag caagctgtgg atactctaaa gcatctctta atgcaccact agcgatctca
    52021 acttggatca atgcaatgat acatgctccc atacaaacta aaatatgcgt acgcatacct
    52081 gctggacgat ttttatattg tcgttcaaaa ccgattgctc cgccaaatag catagcgatc
    52141 cctaaacgta aaataatctc tggaattgtc aataccatat cattcatcta aacaccctcc
    52201 agtccaatat atcatgtctg aaaggagcag acaaaaaaag tgcaattttt acctcttacg
    52261 aaaaaaggac tgtgacaaaa tttttgtcat agtccttttt atgaataaac ggtgttcaat
    52321 cagctgaccc tcggtattac tcaacaaacg gcaaaatatg gggagctatt tttcctttgt
    52381 cttctctaat actcaggtca aaacgctgat ttcacaacct ctttagccta ctattgaaaa
    52441 ttacaactta cttgctgctt cttcatcgat gatcacaaca acattgtcgt gattttgcaa
    52501 tacacttgct ggcaaatgat tcgttacagg tccttcaatc atccctttga ttgcatcagc
    52561 tttgctttcg ccaaatgcca tcaagacgat ttctttactt ttcataattg aaccgattcc
    52621 cattgaaaca gcttttgttg gtacatcttc tgctttatcg aagaatcgtt tgtttgcatt
    52681 gattgttgat tctgttaagt caactactga agtcgttccg tcaaatgaag caccaggttc
    52741 attgaaaccg atatgtccat tttgcccgat tcctaagatt tggatatcga ttggatgtgc
    52801 atcgatgatt tgatcatact ttttgcatgc tgcttccaga tcttctgctt ttccatctgg
    52861 tacaaacgtt tctttgaatg gttttttatc aaataattgg acatccatga aatgacggta
    52921 gctttgttca tctgaaccgc ctagtccaac gtactcatct aagtttacag aagtcatttc
    52981 actgaaatcc aaatcgcttg aagtcatttc tttatataaa gtaactggtg tgcttcctgt
    53041 tgccaatcct aatacttttg cacctttgtt cataccttct ttgatgattt caaatgcttt
    53101 ttttccgcct tcttcagcgt tttttacacg aatgatttcc atagtgattg ctcctttata
    53161 ttttggtata gcccaattat agcattcttt ttttcttttt acaataatta gtatagacca
    53221 aattgcattt ttttcatttt cttgacaata aataggaatc cgtgttaggt ttcataagat
    53281 ggttcaatca aacaatccat gttgcatgaa aaccaagcaa gtgattcact gtggacgctt
    53341 tatgtctgca gtttttttat gaaaaaggag ttattatgag tatactgaca ttaaacaaca
    53401 ttacccagca atttggcgac aaaatcctct atgaaggtgt cgatctgcaa ttaaatgctg
    53461 gcgaacatct tgggctgatt ggacaaaacg gagccggtaa aagtacattg attaaaatca
    53521 tcactggtga gatcttacca gatgacggac agatccattg gcaaaaaaat attcacaaag
    53581 gttacctcga tcaatatgtg gaagtcgatg aaacattaac aatcgaagaa tttctaaaaa
    53641 ctgcgtacgc aaaagaatac gaaaaggaag aaaaaattgc ttttctttac caaacatata
    53701 gcgagacctt cgatgattcc ttgctggaaa aagctgggaa actccaaacg gaattagacc
    53761 aaggagtgtt ttatcaaatc gacaccttag ttgctgagat gagcagcggg ttggggatcg
    53821 atgtcttagg tttagattca ctgttgaaaa atctaagtgg tggacaacgt tcaaaggtga
    53881 ttttagcaaa actactttta gaaaacccag atgttctgat cttagatgaa ccaaccaatc
    53941 acttagatga tcagcatatc caatggctga cgcagtttct tcaggatttt gacggtgcgt
    54001 atatcgtgat ttcccatgac caagaatttc ttgatcagat caccacccat atcgcagaca
    54061 tcgagtttgg aaagattact aagtatactg gccatctaaa acaagcattg aaacaaaagg
    54121 aacaaaatcg cgaaagctat ttgcgccaat atcatgctca acaaaaacaa atcgaaaaga
    54181 ccgaagctta tattcgaaaa tacaaagccg gttcccgatc aacgatggca aaaagccgac
    54241 aaaaacaatt agataaaatc gaacggctga cgcctccagc ttcagcaagt aaagctgtct
    54301 ttgattttcc attctcgcct attgtcacga cattagcagt ggaaacaact gatttagtca
    54361 tcggatatga tcgaccgcta cttgcaccca tcaatttgac catccgcttt ggtgaaaata
    54421 ttgccattcg aggcttcaac gggattggaa aatctacttt attaaaaaca ctgatcggtg
    54481 agattgaaaa aataagtggc gatttccact tcccagataa cacaaaaatc aattactttt
    54541 cacaagatct gtactgggaa aatccattag aaacaccact acaatattta agcagtcaat
    54601 ttccaaaagc gactatcaaa gaattacgtc gccaactagc taaagcaggg ttagttaatc
    54661 aattagcaag tgaacctctc actacattaa gtggtgggga acaaactaag gtgaaacttg
    54721 cacagttgac aatgaaccaa ggtaatttac tgattctcga tgaaccgacg aaccatatcg
    54781 atcaagaaac gaaagaaagc ttacaagacg ggatacagaa atttccagga acagtaatca
    54841 tcgtctctca tgaacaagaa ttttatcaag atcttgtgca acgagtcatt gagattgaac
    54901 caaaataaac gtttgattga atagttgaaa aaaaggagct gtgacaaaag ttttgtcaca
    54961 actccttctt ctgaataaat ggtggccaat tagctgacct tcggtattag ctcaaaaaac
    55021 ggcaaaatat gaggagctat ttttatttgg ctattcttat tacttgatgc agaacagctt
    55081 ttcacaacct cttttcgtct attttttatt ttcgagattt ctctttcctt taaaaacaac
    55141 tgtttgaaag aagaacgcac atccttgaaa aacaagcccg ctaaccgtta cacctaacca
    55201 gccatactgc tgccacattg tcgtccctag caatgaacca gccgcacctc caataaagta
    55261 cataaacata aatacagtat tatttcggtt gcttgctgct tcacctagcc cttgtactcg
    55321 tgtttgattg gcgacttgac caaattgatt cccgacgtct aataaaataa tagctaaaag
    55381 caaaatggcc aaatggcttc cgccaaccaa taaagcaata aagcttattg tttgcataac
    55441 aagtcccata tacacgattt ttctttcaga ataagaatct gccagtcgtc ccacgatagg
    55501 tgcagcaact gctccagaca aaccaaaaat cgctaatatc cctgcttcga atgttcccca
    55561 attgtaggcg ggactgctga tataaaaaat caacgtagac caaaagatcg aaaatgttcc
    55621 aaacatgaaa aatccactga ctgccgcttc tcttaataga cgttgagaag caactaaatg
    55681 cggcaaactt ttaagtgaat caaggtatga aacagctgta ctactttgct ggacagaacg
    55741 cggcattttc cagtaaagca gaagtgtaag aattccgact gcacataaag caaataaata
    55801 gatcatccgc caagaaaaaa gactggcaac aataccagat accgtccgag aaagcaaaat
    55861 ccccacgagt aaaccgctaa gcaatgtacc catgaccttc cctcttgctt ttggtcccgc
    55921 tagtaccgca ccgtaaggaa tgatgatttg cggcacgatc gaaagtaatc ctattaaaaa
    55981 agaagcgcat gcaaataacg taaacgaagg cgcaaaaaaa gcggccaaca gagagacggc
    56041 agataacgct gccattcgaa tgatcaattt tggacgatcc accacgtccc ctaaaggaac
    56101 taaaaacagt aaccctaacg catagcctaa ttgggtcaac atcgtcaata tcccgactgc
    56161 acttgtgcta acagataaac tagctgctac ttttgttcca atcggctgga tgtaatacat
    56221 attggcaaca acaacgccac aagtgattga taatagtaaa ataagcgaag ttgttaaagg
    56281 ttttttttca ttactcttca ttgatttccc ccatttccta tcttagttta caacttatgg
    56341 aaaagattgg aaatagaaaa atacaactat tcgccacact tattatttgt gcttttgttt
    56401 tccttgtttt ttcttgcgat ctttataaat gaagacaact aaccctacta gcacagtaac
    56461 acttgcaacc aacgtgactg cagttttgtt atatccgtga aacagagctt ctccaccaca
    56521 cgcatacaac acagacgaag ggatgactcc aatcacgatc gacaatatga tttgctgtag
    56581 aggcaatttc atcgcatctg cagcaaaatt gaccatagaa gatggaataa ccggtatcat
    56641 atagcctaac attacaccta tttttggatg tttcatttgt cggattgctt gcacccaatg
    56701 attcgtttcg gttttcttat ctaaaaattt taagcgatgc ataaggaaaa ttgcagtgat
    56761 gttaccaaga gcattaccca aaatgttgat gatcgcacct gtcagtggtc caaagctcaa
    56821 accagcaatg actccaacta ctgaagtagg aatacctgga acagcacaca tcaccgctgt
    56881 caatacgatc aagagtatcg atgcaaaagt cccatgcgaa cgaatatgtg cgagtagctc
    56941 tgccttactc gctctcggat ttaaaaataa ttggatgtct gtctgatatt ctaaatacaa
    57001 ccgatagccc actaccagta tcagaatgat tcccaacgag atcaatatca atcggattat
    57061 tttctttttc atatttcctc ctgaaaaaaa tctatattca ttaaataata gtttaacata
    57121 aaaacaaaaa agcaccgaaa tccaacatag gatctcagtg cttttaaata gtaaaaatta
    57181 tttaacagtt acagatgcgc caacttcttc aagtttagct ttcaattctt cagcttcttc
    57241 tttagatacg ccttctttaa ctggtgcagg agcgccatca actacagctt tagcttcttt
    57301 caagcctaaa ccagttgctt cacgaactgc tttgataact ttaacttttt ggtctccagc
    57361 tgcagttaat tctacagtga attctgtttg ttcttcagca gcagcagcgc caccagcagc
    57421 agctacagct acaggagcag cagcagatac gccaaattct tcttcaatag ctttaactag
    57481 gtcgttaagt tctaggatag ttgcttcttt taactcagca acgatgtttt caatgttcaa
    57541 tgccattata atttcctccg tttaattgtt cttttttatt taatgcttta tgcggcaatt
    57601 aagctgcatc tccatcttct ttgtctgcca ctgctttgac agcgtaagcc acgttgcgga
    57661 ctggcgcttg tagtacagat agcaacatag atagaagtcc ttcgcgattt ggcaattttg
    57721 ccaatgctgt gatttcttcc aatgaagaga ctttaccttc gatgataccg cctttgattt
    57781 ctaatgcttt tgcttcttta gcaaattcgt ccatgatttt cgctggtgcg actacatctt
    57841 cgttactgaa tgcaacagct gtaggtccag tgaatacttc gtccatgcct tcaaggccag
    57901 cttttttagc tgcacgtgaa agaatagaat ttttgataac tttcatttct acgttagcat
    57961 cacgaagttg tttacgtaaa cgtgttactt catcaactgt taatccgcgg tagtcaacga
    58021 ctactactga tgcagctgct gtaaattttt cgcttacttc atcaacgatt gctgcttttt
    58081 ttgcgataat tgcttcactc atttttgagt ttcacctcct gaattttgat ggaagagttt
    58141 tttgcactga aaaggcaagt cacttttata gttactttgc tcaaccagta ttattcatca
    58201 cctattcact tcgttcatag tgattctact cgctttgctc gaaaggaaac tcctttcgct
    58261 ttgctcaacc agtattgttc atcatctctt cacttcgttc atagtgattc acaataaaaa
    58321 actctatgcc accgcagaca tagagggact attgaatata ttcaataaac gtcctcggta
    58381 ggaaattaag gcttgatgcc acctactgtc ttcggtacaa gttaattatt aacctcaact
    58441 agcttagcat gctaaactag ttgagtcaag aattattttt cagttggatc aatcaacatt
    58501 ctaatattta attagaaaga agcttggtca acatggatac caggtccaaa tgttgttgtg
    58561 atcgttacat ttttcatgta ttgaccttta gctgctgatg gtttagcttt tagcaataca
    58621 tcatggattg ctgcaaagtt ttcaactaat ttttcatcgt caaatgaaac ttttccgatt
    58681 ggtacatgga tatttccagc tttgtccaca cggtaagtta ctttaccagc tttcacttcg
    58741 tttactgctt ttgttacgtc cattgtaact gtaccagttt tagggtttgg cattaagcct
    58801 tttggtccta atactcgtcc tagacgacct acagtagcca tcatatcagg tgttgcaaca
    58861 actacatcaa agtcaaacca tccgttttgg attttttgaa ccatgtcgtc gtcacctacg
    58921 aaatctgcac cagctgcttc agcttctttt gctttgtctc ctttagcaaa aactaaaaca
    58981 gtttgtgttt taccagttcc gtttggtaat acaacagcac cacggatttg ttggtctgct
    59041 tttttagggt ctacgttcaa acggtatgca acttcaactg ttgcatcaaa ttttgcaatg
    59101 tttgtttctt ttgctaaagc tactgcttcg gcaacaggat aaactttact tgaatcaact
    59161 ttttttaatg catcttgcat ttttttgctc tttttagcca ttttggttcc tccttgattg
    59221 tggttataac ggttgtacct cccacgtgtt ctatatcttt caatatagag ccaactgaga
    59281 agctgctgtc ttagggtgta tagattattc tacagtgatc cccatgcttc gtgcagttcc
    59341 ttcaaccatg cgcattgctg cttcaacgtt agctgcgttt aggtcttcca tttttaattc
    59401 agcgatttct cttacttgat cgctagaaac tttcgcaact ttatttttgt ttggttcgcc
    59461 tgaacctttt tcgattttag ctgctttttt caatagaaca gcagctggcg gtgtttttgt
    59521 aacgaatgtg aatgaacggt cttcgtatac agaaataaca accggaatga tcaaacctgc
    59581 ttgatcagct gtacgagcgt tgaattcttt tgtgaatccc atgatattga tacccgcttg
    59641 acctagtgca ggacctactg gtggagctgg agttgcttta cctgcaggaa tttgcaattt
    59701 aacgattttt tctactttct ttgccacgag acatacctcc ttaagtccgt gatgtggtta
    59761 attggagatg catatttctc ctcccacgtt ttatctgatc tgaaaaaatc cagacaaata
    59821 atgtgcaaaa caatgcacac tggtacagta tagcaaattt atttgttttt tcaagatttt
    59881 tttctgctat ttttacattt tgcttgaata aacgctaaat ttattctaaa aaaacaacaa
    59941 tttttcgttc tcatttcttc ttttatgtta cacttgcgct agcatggttc aacagatgaa
    60001 agcaaacaat aacacggttt tttagaccct tgtacaaaga ttcctacata acaaaatgag
    60061 gtggagaaaa tgaaagattt aaggtataga agtgtctttg atattattgg acctgtgatg
    60121 attggtccaa gtagctctca cactgccgga gctgctagaa tcgggaaaat catacgtagt
    60181 atatttggcg aacagcctga ttctgtagat atttatctat atgaatcatt tgcaaaaacc
    60241 tatcgggggc acggaacaga tattgcatta gttggcggcc tgttagggat ggaacccgat
    60301 gatgaacgtt tagctgattc tttgaaattg gcatatgaag ccggtatgga agtcttgttt
    60361 gttcctaaga gtgaaaaagc cgaacatcca aactctgtaa agatgcttct aaaaaaagga
    60421 acacgaaagc tttcagtcac tggcatttcg atcggcggtg gcaatatcca gatttctgaa
    60481 ttgaatggat tcaaaatttc tttaagcatg ggtactccta ccttgatcgt tgtccaccaa
    60541 gatgttccag gtatgattgc taaagtgact agtatacttt ctgagaccaa tacgaatatc
    60601 ggcactatga cagtgacacg ggaatcaaaa ggtgaaaatg ccattatgat aattgaagta
    60661 gatgatcctc aagtagaaga aacggtaaaa agactcaaac agctgccaaa tatcgacagc
    60721 gtaaattatt tcgattaagg agctaaaaaa atgtttttat cgattgaaga attagtagat
    60781 caagcaaaag cttatccaag tgtagcagaa ttgatgattg cagttgaaat ggaaatgagt
    60841 ggccgttccc gtagtcacat catcgagatc atggaaaaaa acctctcagt aatggaacaa
    60901 tcaatcaacg agggaaaaga aggtgttacc tccgtcacag gaattaccgg tggtgatgca
    60961 aaaaaattag atgattattt aaatgaggca gactttttaa gtggagaaac aatcttaaaa
    61021 gctgtacgca atgctgtagc tgttaatgaa gtcaatgcaa aaatggggtt gatttgtgct
    61081 acaccgactg ccggaagcgc gggtgttgtt cctggtgtgc tgatggctgt ccgagatcgg
    61141 cttgatttga cacatgaaca gcaattggaa ttcttattta ccgctggcgc tttcgggtta
    61201 gtcatcgcaa acaacgcttc tatcagtggt gcagaagggg gatgtcaagc agaagttggt
    61261 tctgcaagtg caatggcagc agcagctttg gtttgtgcaa aaaatgggac tcctcatcaa
    61321 gcagcacaag cagtagccat tacattgaaa aatatgatgg gactgatttg cgatcccgtt
    61381 gcaggcttag ttgaagtccc gtgtgtcaaa cgtaatgctt taggctcttc tcaagctttt
    61441 atctctgctg atatggcatt agcgggtatc gaaagtgtca ttccgccgga tgaagtcgtt
    61501 gctgcaatgt accaagtcgg acgtcaaatg ccgtcgattt tcaaagaaac agcagaaggt
    61561 ggcttagctg ttacgccaac tgctaaacga cttgcggaag agattttaaa taagagggcg
    61621 tgataaagct ccttaatttc gagtattaag agattagtta tcttcataac aaaaaacgaa
    61681 gagaggacta attgcccttc tcttcgtttt ttattaatcc atcaatttcg tattttttac
    61741 ttcatcgatc gtttttgttc ctgcaagttg catcgtgatc gacaattctt tgttcaggtg
    61801 ttcaaaaaca gatgttactc cttctgcccc acctagattc aacccataaa tcactggtcg
    61861 gccaatcgca actaagtcag caccacttgc cagagctttg aagacatgct ctcctcgacg
    61921 gacaccagag tcgaaaatca ctggtacacg tttgttgact acttcggcaa tttttggcaa
    61981 tacttcaaag gacgcaggac ctccatctag ttgacgtcca ccatgattgg atacccagat
    62041 accatctgcc cctgcagaga tagcgattac tgcatcttct ggcgattgta ttccttttac
    62101 gataactgga agatgggtga tttctttgat tgttttgatg tcatctggtg tcaagccttg
    62161 ttttgcagct gcataaattt ctgcgattcc ttttccttcg ccattaccac ttgcactttg
    62221 ttcgctatac gcagctaagt taggcattgg taatggaaat tggaattgat tgatgacgtc
    62281 ttcttcacgg taaccaccga gcgttgaatc tgccgttaaa atgatagctt tagcccctgc
    62341 ttctactgct ttgttcaaaa tgaactcatt gaatctgtcg tctttactca tatataattg
    62401 gaaaaactgc ggtgcgcctg gcgctgcatc ggctgcgtct ttgattgtcg tatttgcata
    62461 agtgctgatg gaaaagattg atccagcagc agctactcct ttagctgtat cagcttcccc
    62521 tttttcatgt gccaatcctt gggccgctga tggcgcttgg ataatcggtg tatctaattc
    62581 aattccgaaa acagatgtat gcaaatcggc tgagtcgatt ccgcgtaata tccgtggcat
    62641 gattttcttt gtattaaaag aagtcgtatt ttctttcatc gtccactcat cttcagaacc
    62701 accgcgaata tagccaaaag ctcctgcttc catgcgctct tttacacgac cttctagtta
    62761 ggcaatgttt acaatatcga ttggatgttc ttcattactt gtatgataag tcatagtaga
    62821 tccttctttc atcttcttga ttacatataa atcatactaa acttacaaaa agtaagcaaa
    62881 catttactct cagatacttt tatcgctatt ctttccaaat aaatcgactt acaagctgat
    62941 ctacttcttg gttttcatga agcatactat gagaggcatt ttcacctgtc actacttttt
    63001 cctctatttc atttccgcgt tgcttcaaca acgcatagac cgctaatgca ctgtttaacg
    63061 gtactgttcc atcactcaag tctgtttcat ctagttgacc agcaatcaag aaaaatcgag
    63121 tggttatagg aatattaccg atcatttgct ggtaatcttg atagcggtta gaaacgacag
    63181 caggcccctt tgctaactca tctgtcagag actgcgcact atcatcgaca aaatcattaa
    63241 aaggcgcgcc aattgctgtt aatgtctgaa cttgtggcaa tgacgtatcc tgtccatacg
    63301 ttcctaaata gcgtagtgca ctaactcctc ccatggaatg ccccactatg ttgactttat
    63361 ctatgccgta gttttctttc agatacaaaa gacaagtttt gatccattct gcttgattcc
    63421 actcgttatt tttattatct tcaaacaata cttggaccat cggattgtct gcttttccag
    63481 acaaatctcc tgttgcttgt atttgtccat ctgttcctac tgttaaaacc aattctttta
    63541 ctgcttgctg atttttttcc aaacgccgca acatcccttt aaaggaattt tctgtcccgc
    63601 tgtagccgtg gaaaaaaagt gttggaatag tggttttttc tatcacttta ctggattctg
    63661 ccgttttttc tttatcagaa acttcagtag tatttatctt cgtcgtctgg caaccactta
    63721 acgcaaacaa actgataagg actaaagctg ctgcagttgc acgtttgcat aaatttttga
    63781 ttggttctgt catacacctc ttcctttcca tatagaaaaa agaaagactt gaaaggccaa
    63841 tcatatgatc gacatttcaa gtctctttat taatcgattt tatctacttg atcgaaatca
    63901 agttctgtac tggtttcacg tccaaacata tcgatgttga ctttcaattt ttctttttct
    63961 ccgtcaactt ctgttacttg tccttctaat ccagcaaatg cgccttcgat gattttcacg
    64021 acttcgccaa cttctacttc tagatcattt tgtcgcaggc tcataccgat agaacgcaag
    64081 atatgattga cttcttctgg aagtaatggt gctggtttgc ttccggctcc gtgtgaacca
    64141 acgaatcctg tcacaccagg tgtgttgcgg acaacatacc atgaagcgtc tgtcatgatc
    64201 atttcaacaa gtacgtatcc tgggaatgtt ttatgaacga tttctttttc tttcccattt
    64261 ttgacttcag tttctttttc ttcaggaaca acgacacgga aaataaagtc ggccattttc
    64321 atactttgcg cacgagattc gatatttgct tttactttgt tttcatatcc tgaatatgta
    64381 tgcaagacat accagttttt ttcaaaagat tccattgaag gctcctcatt tcattgtaaa
    64441 ataaaaaaac ctcagtacac ccgaagtttt tctttcgctt cattatagca ctaaaagtac
    64501 gttgtggcta gcgagttatt ttaaaatcca gccaaataag ctttggatgg ctgtatccat
    64561 tacgtaaaac atcaatccga aaataataga agtttcgatg actactaacg tatctttacg
    64621 gagttgtttt ctgcttggcc aagttacttg tttgatttca tcttttacgc tttttagaaa
    64681 tttcatgaga caacctccct tgctactgtt tatttcgttt ctttatgtaa tgtatattga
    64741 ttacaatatt tacaaaactt attgatttcc aaacgttcgc cgctttttcc ttcactgact
    64801 gattttgtgt agttgcgaga cccacaaacg gaacaagcga gtgctgcttt tttctttgcc
    64861 atttacttct gcccccttgc tgagaatcag acttatactt cataacagta tcacgtaact
    64921 ttttacttgt caatttgtga aataaactat ctattgtttt ggataaaatt atgatatgat
    64981 taatttgaaa ttaagctaaa atgagacaat tggaggtata gcgatgctat taaaaacact
    65041 tgtatataag aaaaaagatc tgacaaccgt tacagagact agtacattag aagaagcatt
    65101 aaaaatttta gaaacttccg gataccgttg tgtgccgatc ttagattctt caggtaatat
    65161 tttccgtgga aacatttaca aaatgcatat ctatcgtcat aaagcaaatg gcggtgatat
    65221 gacgcttcct gtcactcatc ttttgaaaaa cgctacaaag ttcatttacc tggatacttc
    65281 tttcttcaaa gtattcttta cgatcaaaga gcttccttat attgctgtcc ttgacagtga
    65341 aaatcatttt tatggtattt tgacacatag tacgttgctt aatatgctct ctcaatcttg
    65401 gagcgtagaa caaggaagct atgtactgac aattgcttcc acaggaaagc aaggagattt
    65461 ggctgctatt gcaaaaatca tttcaaaaca cagcagcatt gccagctgta ttactcttga
    65521 tatcgaaaaa gacgaataca ttcgacgtac attgatcacg ctaccggcta acactgaagc
    65581 gaaagtatgt gaaacgatcg tcaaccactt agagaaaaag aattataaag tggtagaaat
    65641 tgaaaatttg caaaaccaag aagcataatc aaaaagcgaa aaaagaaaac agctaatctg
    65701 ctttcttttt tcgcttttta taattagaca cgcttttcaa aatcaagcgc gcgatctaaa
    65761 taatacatca atggtgctga aacagccatg acgataaact cacttaatgc aagcgtgcca
    65821 taggttgtcc aaaatgcttg gccacctgtt ggaactaaca tataagcaat cagtcccatg
    65881 ctgatggtaa agaagatcgt gttcaatact aaacgcatct ttacattttt cactttgttt
    65941 tgcaataaag ctgtcaggcc taaagaaagc aatgtttggc cgccaccaaa aaccacatcc
    66001 atgataccaa aaccaaagaa ggcattatag acgatgaccc cgcctaaaac tccccaaagc
    66061 aatttacggt taaagacaac taaatgattc aaactttctg aaatacgaaa ctggatcggc
    66121 cctgaggata caggcgcaac taaaatagtt aacgctagat aaagagccat gatgatgcca
    66181 tttacaacga ttacggataa ccgttgtctg cttttcgttt tttgcatttt ctctcctctt
    66241 ttctcctagt ttttttaacg cgggatggtt gatgaaccgc ggttatgtga aacaaacaat
    66301 aattataaca gacttttcat ttatttcaat ccgtcttatc tgcttttaaa aaagcaaaag
    66361 cttaaacaat gtaaacgttt gctaaaaatc gtgggatatg gtataaagta agtgtaaggg
    66421 gtcataagaa ttcccagtaa agcagacgaa gtaggatctg caagaacaga attgttgtga
    66481 aacttaaata aataaaaaag gatgtgggaa tttgagcaac ctcttactag agaacggtct
    66541 agcaagcagc tgaagatcta agtggacatg ccgaaccttg gaacttctcc ttacgtaagt
    66601 aatggatcat gcgcttgcta ggct
//
LOCUS       DADGKS010000007        66058 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.007, whole genome shotgun sequence.
ACCESSION   DADGKS010000007 DADGKS010000000
VERSION     DADGKS010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 66058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66058
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.007"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(24..722)
                     /locus_tag="JXV47_000469"
     CDS             complement(24..722)
                     /locus_tag="JXV47_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobyric acid synthase"
                     /protein_id="HAX1486537.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(715..2067)
                     /locus_tag="JXV47_000470"
     CDS             complement(715..2067)
                     /locus_tag="JXV47_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HAX1486538.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(2290..3690)
                     /locus_tag="JXV47_000471"
     CDS             complement(2290..3690)
                     /locus_tag="JXV47_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HAX1486539.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            3851..4588
                     /locus_tag="JXV47_000472"
     CDS             3851..4588
                     /locus_tag="JXV47_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HAX1486540.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            4713..5192
                     /locus_tag="JXV47_000473"
     CDS             4713..5192
                     /locus_tag="JXV47_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HAX1486541.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            5189..5956
                     /locus_tag="JXV47_000474"
     CDS             5189..5956
                     /locus_tag="JXV47_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486542.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            6186..6755
                     /gene="lepB"
                     /locus_tag="JXV47_000475"
     CDS             6186..6755
                     /gene="lepB"
                     /locus_tag="JXV47_000475"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAX1486543.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(6859..7461)
                     /locus_tag="JXV47_000476"
     CDS             complement(6859..7461)
                     /locus_tag="JXV47_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAX1486544.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            7567..8036
                     /locus_tag="JXV47_000477"
                     /pseudo
     CDS             7567..8036
                     /locus_tag="JXV47_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            8142..8726
                     /locus_tag="JXV47_000478"
     CDS             8142..8726
                     /locus_tag="JXV47_000478"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HAX1486545.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            8729..9802
                     /gene="prfA"
                     /locus_tag="JXV47_000479"
     CDS             8729..9802
                     /gene="prfA"
                     /locus_tag="JXV47_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HAX1486546.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            9795..10634
                     /gene="prmC"
                     /locus_tag="JXV47_000480"
     CDS             9795..10634
                     /gene="prmC"
                     /locus_tag="JXV47_000480"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HAX1486547.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            10627..10806
                     /locus_tag="JXV47_000481"
     CDS             10627..10806
                     /locus_tag="JXV47_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486548.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            10828..11853
                     /locus_tag="JXV47_000482"
     CDS             10828..11853
                     /locus_tag="JXV47_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HAX1486549.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            12044..13288
                     /locus_tag="JXV47_000483"
     CDS             12044..13288
                     /locus_tag="JXV47_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HAX1486550.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            13441..14388
                     /locus_tag="JXV47_000484"
     CDS             13441..14388
                     /locus_tag="JXV47_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAX1486551.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            14522..15151
                     /gene="upp"
                     /locus_tag="JXV47_000485"
     CDS             14522..15151
                     /gene="upp"
                     /locus_tag="JXV47_000485"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HAX1486552.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(15290..15532)
                     /locus_tag="JXV47_000486"
     CDS             complement(15290..15532)
                     /locus_tag="JXV47_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486553.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            15653..15725
                     /locus_tag="JXV47_000487"
     tRNA            15653..15725
                     /locus_tag="JXV47_000487"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15686..15688,aa:Thr,seq:cgt)
     gene            complement(15844..16482)
                     /locus_tag="JXV47_000488"
     CDS             complement(15844..16482)
                     /locus_tag="JXV47_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAX1486554.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(16605..17237)
                     /locus_tag="JXV47_000489"
     CDS             complement(16605..17237)
                     /locus_tag="JXV47_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAX1486555.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            17588..17887
                     /locus_tag="JXV47_000490"
     CDS             17588..17887
                     /locus_tag="JXV47_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAX1486556.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            18382..20547
                     /gene="acm"
                     /locus_tag="JXV47_000491"
     CDS             18382..20547
                     /gene="acm"
                     /locus_tag="JXV47_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HAX1486557.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(20819..21304)
                     /locus_tag="JXV47_000492"
     CDS             complement(20819..21304)
                     /locus_tag="JXV47_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HAX1486558.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     gene            21784..22425
                     /locus_tag="JXV47_000493"
     CDS             21784..22425
                     /locus_tag="JXV47_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAX1486559.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            22444..23079
                     /locus_tag="JXV47_000494"
     CDS             22444..23079
                     /locus_tag="JXV47_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAX1486560.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            23097..23912
                     /locus_tag="JXV47_000495"
     CDS             23097..23912
                     /locus_tag="JXV47_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HAX1486561.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            24231..25667
                     /locus_tag="JXV47_000496"
     CDS             24231..25667
                     /locus_tag="JXV47_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAX1486562.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            25856..28303
                     /locus_tag="JXV47_000497"
     CDS             25856..28303
                     /locus_tag="JXV47_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAX1486563.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            28533..29600
                     /gene="rlmN"
                     /locus_tag="JXV47_000498"
     CDS             28533..29600
                     /gene="rlmN"
                     /locus_tag="JXV47_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HAX1486564.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(29793..30896)
                     /locus_tag="JXV47_000499"
     CDS             complement(29793..30896)
                     /locus_tag="JXV47_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAX1486565.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            31448..31996
                     /gene="aac(6')"
                     /locus_tag="JXV47_000500"
     CDS             31448..31996
                     /gene="aac(6')"
                     /locus_tag="JXV47_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAX1486566.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            32542..34203
                     /locus_tag="JXV47_000501"
     CDS             32542..34203
                     /locus_tag="JXV47_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAX1486567.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(34273..34620)
                     /locus_tag="JXV47_000502"
     CDS             complement(34273..34620)
                     /locus_tag="JXV47_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HAX1486568.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSTLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            34704..35645
                     /locus_tag="JXV47_000503"
     CDS             34704..35645
                     /locus_tag="JXV47_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1486569.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            35646..36689
                     /locus_tag="JXV47_000504"
     CDS             35646..36689
                     /locus_tag="JXV47_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1486570.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            36695..37765
                     /locus_tag="JXV47_000505"
     CDS             36695..37765
                     /locus_tag="JXV47_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1486571.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            37755..38708
                     /locus_tag="JXV47_000506"
     CDS             37755..38708
                     /locus_tag="JXV47_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAX1486572.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            38720..39730
                     /locus_tag="JXV47_000507"
     CDS             38720..39730
                     /locus_tag="JXV47_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAX1486573.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(40015..40836)
                     /locus_tag="JXV47_000508"
     CDS             complement(40015..40836)
                     /locus_tag="JXV47_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAX1486574.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(40933..41211)
                     /locus_tag="JXV47_000509"
     CDS             complement(40933..41211)
                     /locus_tag="JXV47_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486575.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            41479..43488
                     /gene="metG"
                     /locus_tag="JXV47_000510"
     CDS             41479..43488
                     /gene="metG"
                     /locus_tag="JXV47_000510"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HAX1486576.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(43967..44554)
                     /locus_tag="JXV47_000511"
     CDS             complement(43967..44554)
                     /locus_tag="JXV47_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486577.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            44729..46051
                     /locus_tag="JXV47_000512"
     CDS             44729..46051
                     /locus_tag="JXV47_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAX1486578.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            46206..46982
                     /locus_tag="JXV47_000513"
     CDS             46206..46982
                     /locus_tag="JXV47_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAX1486579.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            46975..47544
                     /gene="rnmV"
                     /locus_tag="JXV47_000514"
     CDS             46975..47544
                     /gene="rnmV"
                     /locus_tag="JXV47_000514"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HAX1486580.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            47537..48421
                     /gene="rsmA"
                     /locus_tag="JXV47_000515"
     CDS             47537..48421
                     /gene="rsmA"
                     /locus_tag="JXV47_000515"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HAX1486581.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            48872..49501
                     /locus_tag="JXV47_000516"
     CDS             48872..49501
                     /locus_tag="JXV47_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486582.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(49625..50734)
                     /gene="ugpC"
                     /locus_tag="JXV47_000517"
     CDS             complement(49625..50734)
                     /gene="ugpC"
                     /locus_tag="JXV47_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HAX1486583.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            50943..51365
                     /gene="mgsA"
                     /locus_tag="JXV47_000518"
     CDS             50943..51365
                     /gene="mgsA"
                     /locus_tag="JXV47_000518"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HAX1486584.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            51688..52224
                     /locus_tag="JXV47_000519"
     CDS             51688..52224
                     /locus_tag="JXV47_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAX1486585.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(52264..54027)
                     /locus_tag="JXV47_000520"
     CDS             complement(52264..54027)
                     /locus_tag="JXV47_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1486586.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(54030..55745)
                     /locus_tag="JXV47_000521"
     CDS             complement(54030..55745)
                     /locus_tag="JXV47_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1486587.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(56524..56748)
                     /locus_tag="JXV47_000522"
     CDS             complement(56524..56748)
                     /locus_tag="JXV47_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486588.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            56948..59716
                     /locus_tag="JXV47_000523"
     CDS             56948..59716
                     /locus_tag="JXV47_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAX1486589.1"
                     /translation="MLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNTVSH
                     YLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQPKDL
                     FSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLHDLL
                     EDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLDEVH
                     RLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRIPIR
                     IELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGELKNI
                     VKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLMEKQ
                     QPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHELLVY
                     WTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELEQQV
                     SQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIAAHG
                     YATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILVDMG
                     SLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPEWRL
                     LYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNSDPL
                     FSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQRII
                     RNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLIERL
                     IRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSEDTE
                     FLSIEEEF"
     gene            59797..60216
                     /locus_tag="JXV47_000524"
     CDS             59797..60216
                     /locus_tag="JXV47_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HAX1486590.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            60228..60698
                     /locus_tag="JXV47_000525"
     CDS             60228..60698
                     /locus_tag="JXV47_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAX1486591.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            60715..61494
                     /locus_tag="JXV47_000526"
     CDS             60715..61494
                     /locus_tag="JXV47_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1486592.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            61481..62302
                     /locus_tag="JXV47_000527"
     CDS             61481..62302
                     /locus_tag="JXV47_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAX1486593.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            62319..63368
                     /locus_tag="JXV47_000528"
     CDS             62319..63368
                     /locus_tag="JXV47_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAX1486594.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            63381..64385
                     /locus_tag="JXV47_000529"
     CDS             63381..64385
                     /locus_tag="JXV47_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAX1486595.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            65018..66037
                     /locus_tag="JXV47_000530"
     CDS             65018..66037
                     /locus_tag="JXV47_000530"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAX1486596.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT        22110 a        11477 c        13459 g        19012 t
ORIGIN      
        1 tcacattccc ctttttcgaa taactaggct gtttgtcctt caagataggg cagatccaat
       61 tctttaccgt aacgttgttc taaagctagg cggatcaaac gagctgccag gttctcattt
      121 cttgcaagga taggtccatg gaaataagaa ccgaagacat ttcggtaaat gacaccttca
      181 gattggtctt caccattatt tccttgacct tgtaccactt tccccaaagg tcgttcacct
      241 tcacctaaga aagtccgacc attgtggttt tcaaatccat aataagtttc attgaattct
      301 tcgttatgga taacgatatc accgataaac cggttatttt cctgacttaa cgtgtagtga
      361 tccagtgcac tgattccttg gatcttttct ccattagctc ccatgtagta gtgacctagc
      421 aattggtagc caccacaaat ggctaacatg acgccatcat tttcgatata gttgatcaaa
      481 gaatctttct ttttctggat gtcttttgaa atgattaatt gctcaaagtc ttgaccaccg
      541 ccaaagaaaa ccaagtcata tttatcagca tcaaaaggtt catgtatact aacgatctcc
      601 gtatggcaag aaacccccat tttttctgct atatatttca acatcaaaag gtttccgtta
      661 tcaccatatg tgttcatcaa atttccataa aggtgggcga tattgagttc ataattagcc
      721 acggttcatt cctcctttga taaatccttg agcagctagt tctttacgaa gctgcaatac
      781 agcagtgtaa gtagctaaaa tatagacatg ctcagttggc aattctttga ttttttcgat
      841 tacttctggt aattcttttg tttctgtcaa tttattttct ggaatcccgg caacttttag
      901 acgtaaagtc atatctgtat gacggtctcc tccagaaata acagctggga tatccatatc
      961 ggcaaagttt tcaaaattac catcccaaat ccagctgaca tcgattccgt ctgcgtaatt
     1021 ggcatttaat aaagccacta aagaaaatgg ataaggagct agaccaatca tatcgattac
     1081 ttgattgata cctacaggat ttttgacaag tactaatgta cattttttcc cattgatatt
     1141 gatgacttct tgtcggccga atactttctc gtcatatcct aaaccttgtt tgattttatc
     1201 aggatcgaca ttgaagtact ctgccactgc agtagctgct aaagcattgt agacattata
     1261 cataccgcca acttcgattc cgtattcatg accatcgatc acgaaatctg ctgacacatt
     1321 gtccatccgt accatatcag ttaatcgata atccaattca ggacgtttga agtcacaatt
     1381 tggacagtaa tatttcccta agtttgcata agtgatcatt ttataatgca agatgtgatg
     1441 acaatttgga cataagacac cgtctgtatt gtaatgagcc atttgttcac gatcttcttc
     1501 atggtcaaag ccataatatt ttctaggatt gactgtttcg atagaattga agattggtga
     1561 atcaccgtta ctgataatcg ttgcatttgg tgactttgcg gcaccgtcta caatcatttt
     1621 ataggtcgta tagatttctc cataccgatc catttgatca cggaaaatat ttgtaaataa
     1681 gaacagttct ggtttcatat attctgtgac tttgctcaaa cttgcttcat ctatttctag
     1741 gacagcaaac tttttctgtc ctttttttgg ttttgcctgc aagaaagtcg atacaattcc
     1801 ctgtaccata ttcgcaccag tagggttggt tagaacttca tcgaattgct ggcgcaaaat
     1861 attgactgtt aaagcggtag tcaatgtttt accgtttgtt ccggtgacaa cgacgacttg
     1921 gtagtctttt gccaaactat ctagtatatg tggatcgact ttcagcgcta gtttacctgg
     1981 taaacttgat ccgcctttaa aaaaagtttt taatgcccat tgcgacgttt ttccaactgc
     2041 aatcgcaaaa tgactgcgta ttcccattat gtaacctcca aaaacgattt gctgacgaat
     2101 aaattcaact aatcatacca tatgttgaaa aaaaggttaa attgcttttc ttattcttaa
     2161 gaaaaggtta cggctgaaag tgcatgaaat cggacaaaat cgcatgattt aacaaaaaaa
     2221 cagcttgaaa caaaatgatt gtttcaagct gctgtgattt tattattccc tcttacctat
     2281 attcccattt taaccgataa taattttctc gcttggatat tcatagccta gatctcgtgt
     2341 ttcttttggc acgaataaca tcaatgtata tagcattccg atccgcccaa taaacatcag
     2401 tgtagcaatc gtgattttgc ccacaacaga caagtctccg gtaatcccta aagataaacc
     2461 agttgttcca aacgcagaag ttacttcgat gatgatcgag atcagcgttt gttcttctgt
     2521 agcagataaa aaaacgatac aaaagaaaca cataccaaga gaaagcataa agacaacgac
     2581 tgattttcgc acatcatctt gatcgattct ccgtccaaaa atattgatgt tatcttcact
     2641 tttgaggaag gaatatagat acaaaccgat gattgctaca gtagttgttc gaatcccgcc
     2701 gcctacagaa ctaggactgc atccgataaa catcagtaaa gaaaaaatga tcagtgttgt
     2761 gatttgaaaa tcacccaaat cgtgaatctg cagaccagca ttacgagtcg taatcgaata
     2821 aaacatcgaa ttgatccatt tgacactcat attggaatct tggaataaat ggtccttttc
     2881 caatagataa atcaagacag ttcccgaaac aaacaagata acaaaagcta acacagctaa
     2941 tttggtaaac aaggaaaaac gaaacggaag cttcgcattg gaacgtttgt ataatagcca
     3001 ttcccggcac tccatcaata caggaaaacc aattcctccg acaaaaatca aaaacatgat
     3061 caggatcaag aaaaaatagt catgtgcaaa gggcttgatg gaatccccag tgacgtcaaa
     3121 cccagagttc gtgacagccg atatcgcctg ataaaaaccg taaaaaacgg catcacgcca
     3181 acgatcaaaa tagcctctgt aataaaaata aatagaaaag aatgtcccaa aaagtaattg
     3241 aaaccagatt aaaatagcaa aagtgatccg aatcagtcgg acgataccag acaaacgcgg
     3301 ttgattcata tccgtcatga tcagctgtcg ctgtttcagt gtgatccgtc gtttagaaaa
     3361 aatgacaaaa gcagtagaaa tcatcatgat ccccaaacca ccaacttgaa ataatatttc
     3421 cagcagtata ataccgttat cattgaacac agaattgata tcaaaagtcg atagtccagt
     3481 cacactcact gtactgattg ccatgaacag catgtccaca aaagaaacat ggctatctgg
     3541 ttcgcgaaaa atcggcatat aaaatagaac gagtgataag accgtcatca atatataata
     3601 aaaaacgatg atttggatcg atgagaaatg attggcagca aacttctgtc ctcgccgctg
     3661 cagccttcga aagaataaat caacatgcac agtactatcc tcctgacaat agtcgtttct
     3721 accagtatac aaggggaatt aggaatactc aaagaaatta tcaaacagat aacaatacag
     3781 ctttcgatta aaatagaaat ggcttataat aaggaaaatc ctagaaaaaa gaaggaggag
     3841 gaataacaaa ttgattaatg ctcaacaaat cgtagaaaaa atgaaaaatc aaaaaataaa
     3901 ttatgataca gttctgaaaa aaatgatcat gcaatgggag aaagaagaag taaagcctaa
     3961 gatattaata catacatgct gtgctccttg cagtacgcac acattggaat tcatgtctca
     4021 atatgcagag atcacgttat ttttttcaaa ttcgaatatt catcctaaaa gtgagtattt
     4081 gcgaagatta catgaacaaa aacgatttgt agaccaattt aatgagaaaa ctgaccatca
     4141 tgttgcgcta atcgttgatg aataccgtcc aaatgaattc accaaaatgg ttttaacaaa
     4201 ccatcttgaa aacgaaaaag aaggtggtgc tcgctgcagt gcatgcttca atatgcgatt
     4261 agatcttgtt gcgcaaaaag cgcaagaact aggatacgat tactttggaa gtgccctgac
     4321 catctcgcca aagaaaaatg cagctttgat caatcagatc ggaatggata tccaaaagat
     4381 ttacgggaca caatacttgc caagtgattt caagaaaaac aaaggctatg aacgctcttt
     4441 gcaaatgtgc aaagagtatg atatttatcg ccaatgttat tgtggttgcg tgttcgctgc
     4501 caagcagcaa ggatgcgatc tgaaagaaat caatcgggaa gcaaaagctt acttaaaaac
     4561 atcaaccgta gtttttgagg aaaattaaag aaatctttcg gaaaaacgta agaaaaaaat
     4621 aaagaattta tggtagaaat aaggtagact gtataatttg tccgtagtaa agtaaggaaa
     4681 caagaataaa tttcaatgaa ggaagagata agatgcgaaa agtagcacct attttgaagc
     4741 caatcgctgt attaacaatc tcgacgattg tcgcgactac tacaggtatt gtgaatagtt
     4801 ccagctaccg tgcaccaagt tcaagttcta gtactgtaga agaaacaaca ccaactactt
     4861 cagtctcgac atctgaacca acaacaacgg aaagtttgaa tgaaaccact acgacaagta
     4921 catgggacga tacaacaact agttcgtcgt atgatgagac atatacaact gacagctcaa
     4981 gcgaaacaag taatacggta ccagatggca ctccatcgga ttcaaccaat ccaagtacaa
     5041 gtccggatac aagtgctagc tccgaaacga taccaagcag tacgactgta gatgataaca
     5101 cgcaaaatga tgatgcagca cgtacagcac agcaaaacca agattcagga aatacccaaa
     5161 cgtataacca gcaagcaggt gattctcaat gacattttta ctagacctta tcaacggggt
     5221 gcataaattc cttggctatt tagacatcag tcctaaatat cttaaccgtg gatatacgat
     5281 tttaagtgtg attcccacgc tttatttatt gagaattgtt tatggacttt ggcaaaacca
     5341 aaactatctt caatttttct tatatggact tgcatttcta gtgcttgttt attttactgt
     5401 tttaaatgta ttttattact ttttagataa aaacacgaaa gccgatgtca ctcagctttt
     5461 tgtgaagtat ttacctgatg aagcgttcaa catccagaca gaagaatcga tagataatgg
     5521 aaattcgatc gataaagtga atacacaaga ggtcatggtt tcttatgacg aagattatca
     5581 attgaaatta gccgagaata tgcggtattt gattggaaat ggtgagatca aaacaaatga
     5641 actcggtcgc atggatggat ttctggtcga tagaaataca ttgtatcctt attactatgt
     5701 caagaaaaca ggagagaaag agtatgttct aaatattgga cgaagctact cggacatgga
     5761 aaaagtaggg accattcgac ttgactcaac agaagacaca ttggaacctg tcggattgtt
     5821 catcgtcggc ggtgattttg tcaaagacgg gttacgctat catgagcctt atcgtctgaa
     5881 attgattgca aaaaaggcac agtcgcagga agaaccagtg gtttatagtc gtagccaaag
     5941 aagaagacat tcataatgtg atgaaacgcc gtgtatcagt ggttgcgata aaaacgttta
     6001 ttcggaataa gggggatgtg acacgtcttt tgtcacgttc cttttttata taacgagaaa
     6061 gataagacga acacatcact tattctttcc tttcatttat aaacattgta gaataaagaa
     6121 agtacaacga agtattgtga aaaaacgtaa taaataacga ggaaaataca agtaggaggt
     6181 aagctgtgaa agaatttttg aaaaattggg ggattttgat ccttgtatta gcggctattt
     6241 tattagctag agtgtacgtg tttacaccag ttactgtaaa cgggcattcg atggacccta
     6301 cattaagtga tggacaacga ttgatttcat ctaagatctc aaactatgaa cgaatggata
     6361 ttattactac aaaggaaccg ggggatgaag aacggatgat tgttaaacgg atcatcggta
     6421 tgcctggaga tacagtcaag atggaaaatg accagttgac cattaatggc aaaaagtatg
     6481 atgaacctta tctggatgag ttcaaaaaag aattttcaga agataagtta caaggagaat
     6541 atgcttatag ctcaggattc caagcacaag cagaaagttc atccaccttt acgagtgact
     6601 ttgaatatac tgtgccaaaa ggaaagtatc ttgttctagg cgataaccgc ttgatttcaa
     6661 aagacagccg aatgtttggg ttagtcgaca aagatatgat ccaaggaaaa gttgttttcc
     6721 gttattggcc tctttcagaa attaaaatca tgtgatgaaa aaataaaaag aagctgtgac
     6781 atgttttttg tcacagcttc tttttccgaa aattccttct tatttcttgg agttgctcac
     6841 tttttttgca atctcatttt aagctttttg gctgatggat aagaaaagcg aagcgttttt
     6901 gttcataaat agcttttccc cacgatggaa ggtatgacta gtagcagaga caaagcccgt
     6961 tttttccaat cgattattca attcttcttg gctaaagcca ttatggactt tcggatgact
     7021 aatttgttca ttcttgtcaa agtctacgat gatcaattga ccgccaggag ctaaaatttc
     7081 ataaagtttt gtaagaatat tctccgtatc aggaatgtgt aaaagtacaa gtgatagaag
     7141 gatgagatta gcttggacag caggaaattc gacagaagca tcagcgtgga tcgttcggac
     7201 atttttcaga tctgctgctt ggatcttttc ttctgccatt ttcagcatag tttctgaagc
     7261 atcggcaatg atcagttctt tgaatctttc cgcaagcggt aaactaacaa gcccagttcc
     7321 gcctccgtaa tccagcagga ctttttggtg gctgtcgcgc ggtagataag tagttagttc
     7381 ttcgcgaata atcttggcta atgcttgacg gtcaggggaa tcataatggt tagcgatgga
     7441 atcaaaaata ttttttgtca tcaaatagct ccttacgtaa aactttgaaa ttttaactta
     7501 ttatagcacg tgaaaagaaa gaaagcatgc tatactcaat tcaaaaaggg agaatctaga
     7561 aagaatatgc cgatatcgtt tgtaaaagat agagaggaaa aaggaaagtg tgtccgagaa
     7621 atattactag acttgcctga gtggtttggg cttcctgaat caacggaaaa atatatcgag
     7681 gaatcaagta aactaccttt atggtgtgaa aaaagaaaag aagaatattt aggctttatc
     7741 actctttcac agacaagtga agatactgcc gaaatctatt ctattgtatg ggaataaaaa
     7801 aagactatca tcaccaagga ttaggaacaa aactttttaa agaagcagaa ggttacgcag
     7861 caaaacatta caaatatttg caagtgaaga ctgtagacga ggggcactac tctatatatg
     7921 atcaaactat ttgtttctac gaatcattag gattttcaag gttggaagtt tttccaaatt
     7981 tatgggatga atggaaccca tgtttagttc ttgtcaaaaa attggaacaa aagtgagcaa
     8041 tagatttaat actaatctgt gcttgatgaa aattctcact gtaaaaaatg ctgaaaatca
     8101 agtataatac cataggaaca aactggaagg tgaaaaagag catggcacaa ctatttttta
     8161 agtatggcgc aatgaatagc ggcaagacga tcgagatcct aaaagtcgca cataattatg
     8221 aagaacaaaa taagccagtt gtcttaatga caagcggtat tgatacaaga gatggtttag
     8281 gcgttgtttc aagccgaatc ggactgaaac gtaatgcgat gccgatattt gaagaaacag
     8341 acgtatttga cgtaattcag aaaatggaaa gcaaacccta ttgtgtgctg atcgatgaag
     8401 cgcaattctt aaaaaagaaa catgtcattg cttttacgag aattgtggac gaattggata
     8461 ttccggttat ggcatttggt ttgaaaaatg attttcgaaa cgagttattt gaaggatcaa
     8521 aatatttatt gctttatgca gacaaaatcg aagaaatgaa aacaatctgt tggttctgcc
     8581 acaaaaaagc aatcatgaat ttacattata ttgatggaaa ccctgtttat gaaggcgatc
     8641 aagtgcaaat tggcggaaat gaagcttatt accccgtttg tcgaaaacat tactttcacc
     8701 catcaatgat tacagaagga gaataagcat gtacgatcaa ttacaagcaa ttgaagaccg
     8761 ttatgaagag cttggagaac ttttaagtga cccagaagtg atttctgata caaagcgttt
     8821 tatgcagctt tcaaaagaag aagcaaacac gcgcgaaaca gtcgaagttt atcgtcgtta
     8881 taaagaagta gtacaaggaa tcaccgatac agaagaactg cttggtgaaa aactggatga
     8941 tgaaatggct gaactagcaa aagaagaatt atctgaatta aaaaaagaaa aagaagtctt
     9001 agaagaaaaa atcaagatct tgcttttacc aaaagatcca aatgacgata aaaatatcat
     9061 catggaaatc cgtggagcag caggcggaga cgaagcagca ttattcgctg gcgatctttt
     9121 caatatgtac caaaagtatg ctgaagcaca aggctggaaa acagaagtga tggaagctaa
     9181 cgttaccgga atcggtggat ataaagaagt gatcatgatg atcaccggag acaacgtata
     9241 ttcgaaatta aaatatgaaa gtggtgcgca ccgcgtccag cgtgttcctt caactgaatc
     9301 gcaagggcgt atccatactt ccaccgcaac agttgtcgtg atgccagaag ctgaagaagt
     9361 agagatcgat attgaagaca aagatatccg tacagatatc tatcatgctt caggtgctgg
     9421 cggacagcac gtcaataaaa cagcatctgc tgtacgtttg actcacttac caacagggat
     9481 cgttgttgct atgcaagatg aacgttctca aatcaagaac cgtgaaaaag caatgaaaat
     9541 cttgcgtgct cgtgtgtacg ataagatcca gcaagaagca caaagcgagt atgatgccaa
     9601 tcgaaaatca gcagtcggaa ctggggatcg ttcagaacgg atccggacgt ataatttccc
     9661 gcaaaatcgt gtgactgatc atcgtatcgg attaactatc caaaaattag atcagatttt
     9721 agcagggaaa ttagatgaga tcgttgatgc attgatcatg tatgatcaaa catcaaaact
     9781 ggaagctatg caaaatgggt aaaatgacct atcgagaagt cctgtcacgg gcttcttctt
     9841 ttttagagga tcatgggaaa gaagcatata gtatccaatt tttatttttg gaacgaaaac
     9901 aatggaaaaa acttgattgg ctccttcata tgaacgaaga gatttcagaa gaagaacagc
     9961 ggttgatcga aaccgatctg cgacttctgc ttgcagatca tccacctcag tatttgctag
    10021 gatatgcaga tttttatgat catcggttaa aggtaactga agcaacactg atccctcgac
    10081 cagaaacaga ggagttagtc gaatggtgtt tagacgagac gcctggtgta ccgttagaag
    10141 tgatagatat tgggacaggg actggagcaa ttgctattag tttgaaagca gcaagaaaaa
    10201 attggcatat atctgctgtg gatctttcag aagaagcatt agaagtagcg aaagaaaatg
    10261 ctcagaaaga aggaacgaaa atcagttttt atcatggaga tacattagga ccagtaatgg
    10321 atcagcaatt tgatgtgatt atttctaatc cgccgtacat cagtcggaat gaatgggaac
    10381 tgatggatga aagtgtccgg tcattcgaac ctaaaatggc cctttttgct gagaacgatg
    10441 gattagctat ttatgaaaaa atagcagttg aagcaccaag cgtactaaaa tcaaatggaa
    10501 agattttttt agaaatcgga tttcgccaag gtgaagcagt aaaaaaaata tttcagcaag
    10561 catttccaga taaaaaagtg gcgataaaaa aggatctttt tggcaatgaa cgaatgatcc
    10621 aagtttatgg ttgaagttgt ggatgaaaaa ttttttattt gtttttttat tataaaaaaa
    10681 cacttatttg acaaggatgt aaacgacttt ttggtttatc aacaagttta tccactattg
    10741 acaaatagat tatccacaaa cagtggaaaa cttgaggata aactcagaca aaataagaat
    10801 gtatgaaaaa ggggttgtgg ataaactgtg gaaacgaaac gatatgatga aacagaattg
    10861 caagaggcag ccgaagcact gaaagaagga gaacttgttg cttttcctac cgaaacagta
    10921 tacggattgg gcgccaacgc tcttttacca aacgctgtca agaaagtgtt ttctgtaaaa
    10981 gggagaccgc aagataatcc attaatcgtc catgtcgcct cttttgaaca agtaaaagag
    11041 tatgtggaca actttcatcc ggcagcagag aagattgtga agaacttctg gcctggacca
    11101 ttaactttga tatttaagat caaaaaagac actttgccct cagttgtgac gggaggatta
    11161 tccacagctg catttcgtat accggataac aaaaaaacac tagaagtaat cgaactttcc
    11221 ggtgttccgc ttgtcggtcc aagtgcaaat acgtcgggaa aaccaagtcc aacgactgca
    11281 gatcatgtat atcatgatct acaaggaaaa attaccggga ttattgatga tggagctacg
    11341 cgaattggtg tagaatccac tgttcttgat ttaagtgatc caacagccat gcctatgatt
    11401 ttacgaccag gtgcagtaac gaaagaacaa atcgaagcag tcatcgaatc tcctgttgct
    11461 attgatcagc atcttgtaaa agaaaatgaa acaccaaaag cccctgggat gaaatacaaa
    11521 cactactcac ccgatacacg tgttctgatg gtcagagatg gcgattggtc aactgcagtt
    11581 caatgggcaa aaaataagaa gatccgtgca ggtgtcatag caagccccga aattgcggat
    11641 caagtgcgga cagatactgc agctgtttat atgtataacg acaactcagt agaagcggcg
    11701 gctaaaggat tgtttgcagg tctaagagga ttagatgaac caacacttgg attagatttg
    11761 atttttgtac aagtgtatcc agaaactgga ttggggaatg cttacatgaa tcgcttgaaa
    11821 aaagcagcag gacaaaatta ttttgaaaaa tgatcaattg gttattgtcg cattctttta
    11881 gtatgataca atgctatcaa gtaaatcttc tatcagtgaa cgaaaaacta agcgtaacta
    11941 atcgtaatag aagagatacg aatatttggc aatttgtttt tgatgggaaa aataaaattg
    12001 taggaaaata aaattgtagg aaaataaaaa ggagctgttg tttgtggtag attacaaaac
    12061 gtttgaccct gatctttggg ctgcgatcgc caaagaagaa gaaagacaag aacataattt
    12121 ggagctgatt gcctctgaaa actttgtctc cgaagcagtg atggctgcac aaggaagtat
    12181 cttgacaaat aaatacgcag aaggttatcc agggcatcgc tattatggtg ggtgtgaatt
    12241 tgtcgatatc gttgaaaatt tagcgattga ccgtgcaaaa gaattattcg gagcgaaatt
    12301 tgcgaacgtc cagcctcact ccggctctca agccaacacg gctgcttatc tcgctttggt
    12361 agaaccaggg gacacgatct taggaatgga tctttccgca ggcggacatc taacacatgg
    12421 atcaccagtc aacttcagtg gcaaaaccta tcactttgtt gcttacggtg ttgatccgac
    12481 aacagaagtt attgattata atgtggtacg tattttagct agaaaacatc aaccaaaatt
    12541 gatcgtagca ggtgccagtg cttacggacg aacgatcgac tttgcgaaat tcagagaaat
    12601 cgcagatgaa gtaggcgcaa aactgatggt agatatggca catatcgcag gattagtagc
    12661 agcaggactt catcctaatc cagttcctta tgcagatatc acaacgacta ccactcataa
    12721 aacattgcgt ggccctcgag gcggcatgat tttgacaaac gatgaagcat tagcaaaaaa
    12781 aataaatagt gcggtatttc ctggtattca aggcggccct ctagagcatg tgattgcggg
    12841 taaagcagta gcattcaaag aagcattaga tcctgcattt aaagaatata gtgaacaaat
    12901 catcgccaat gcaaaagcaa tggtcaaagt tttcaatcaa gcaattggaa ccagagtcat
    12961 ttcaggggcg acagataatc atctgatgtt gatcgatgtt cgcgagttag gtataaatgg
    13021 aaaagaagca gagagcattt tggacagtgt gaatatcact gtaaataaaa actcgattcc
    13081 ttttgaaaca ctaagtccat tcaaaacaag cggtattcga atcggcacgc cagcaatcac
    13141 tactcgcggg ttcaaagaag aagatgctgt aaaagtggct gaactagttg tcaaagcatt
    13201 acaagcaaaa gatgataacg ctcaactaga cgaagtcaaa acaggtgtac gcgaattaac
    13261 tgaaaaattt ccgttgcata aaaaataaaa atttaaattc cattagtaaa cagaaaagtt
    13321 caatgttggg cttttctgtt tattttttgg gaaaacggat tctttgacaa tatcggtgat
    13381 gctctctagt atatgaggtg taattttagt cttcacacta aatctcaggg aggaaaagtc
    13441 atgactgatc gtatctcgtt agaaaaggaa gcagtagcat tcagtgatgc aaatgcgcct
    13501 catccgcgta tctatgaact agcaccggaa gaaggaagag ttttactaga agaagtacaa
    13561 gaatcacctg tgaacaaata ttccgtcgat attgaagact tgatggtgga tactggcgaa
    13621 tggggaaaac tcaatattcg tctcgtacga ccagaaggga atatggataa attaccagtt
    13681 attttttata ttcatggagc aggctgggtt tttggcagtg ctcaaaccca tgataaattg
    13741 atcagagaac ttgcggttcg tacgaattcc gtcgttgtct ttccagaata tagtcgatca
    13801 ccagaagcaa aatatccaac agcaattgaa caaaattatg ctgtgttgca acagctgaat
    13861 aaattagcca agtcaaaaaa tctggatctc gagaatctaa tcgttgcagg agattcagta
    13921 ggtggtaaca tggctacagt catgacgatc ttaacaaaag aacgaaaggg cctcccaata
    13981 tccaagcaat tgctgtatta tccagtcaca aacgctgatt ttgatacaga ttcctatcat
    14041 gaattcggag aaaactattt tttgacaaga gaaggaatga tgtggttttg ggaccaatat
    14101 acgacgaatg aagaagagcg tgctgaaatc acagcttcgc ctttgagagc aaatataaat
    14161 gaactaaatg atcttccttc agcaatgatt ttaacgggag aagcggatgt attaagagat
    14221 gaaggtgagg cttatgcgcg caaacttcgt gatgcagggg ttcctgttac acaagtacgc
    14281 ttccaaggaa tcatccatga ttttgtcatg gtaaatgcta tggatcagac aaaggcaacg
    14341 cgtgcagcaa tggcattatc tacttcttgg atcaagaaaa aagaataagc tttgcttgtc
    14401 cgcaggaaaa cttcttttca aaaacggatt ttcttaggaa aaatggcgag tttgactagt
    14461 caatcacttg attttgtttt acaattaaaa agaaacgaca gaacaaagga gagcttaaaa
    14521 aatgggcaaa tttcaagtga tcgatcatcc attgattcaa cacaaactaa ctattattcg
    14581 ggacaaaaac tgcggaacaa aggtttttcg tgaagtagtc gatgaaatcg ctatgttgat
    14641 ggcatatgaa gtatcacggg atatgccatt ggaagacatc gtgatcgaaa caccgatcac
    14701 tgaaacaaca caaaaaacgt tgtctggtaa aaaagtagcg attattccaa tcttgcgcgc
    14761 aggtattgga atggttgacg gtatcttgga attgattcca gctgctaaag tgggacatat
    14821 cggtctttat cgagatgaag aaacattgga accacatgaa tatttcgtca aacttccaga
    14881 agacattgat gcacgtcagt tgtttgtagt agatccaatg ttggcaacag gcggatcagc
    14941 aatcatggca atcgatgcat tgaaagaacg tggcgcgtcg aacattaaat ttgtttgttt
    15001 ggtagcagca cctgagggag taaaagcttt gcaagaagcg catcctgata ttgacatcta
    15061 tacagcttct ctagatgaaa aattgaatga acatggttat atcgttcctg gactagggga
    15121 tgcgggtgac cgtttgtttg gtacaaaata agtaaatacg aaaaagggtg tgacacaact
    15181 tttgtcacat ccttttttgg tcatttttaa cgtttgatgc agaacagctt tttcacagct
    15241 ttcgtttgca tataaaaaaa ccatcccaaa aatgcagaga tggtcaaatt caaatctttt
    15301 ttagttcttt gtagttaacg attactacac ccttactttg cgtcatcaag ttcgcatttt
    15361 ctgcagtttc atcaatctca acaacagcgg aatttttcaa ttgctttgaa atcgttccag
    15421 tttgcgactt gccgtgaatt gtgaacatta cgtgagtatt gatcttgaat ttttcaccaa
    15481 tttccgatgg tacgatagtt gtatcaaatt ttccaaaagt tgccattttc ataaaacctg
    15541 cctttcacat caattatacc acgttttatg aaaaatatca tgaaattaaa ctaattttcc
    15601 atcggactct ttacaatcag ccaaatagag tatataattt cttttggata aggccagctt
    15661 agctcagttg gtagagcaac gcactcgtaa cgcgtaggtc gtaggttcga tccctatagc
    15721 tggcattaaa agagaagaca gatatatcaa ggatttttaa tccattgata catctgtctt
    15781 tttgtttaaa ggaaataaag tatgctttct tagcaataga gcatgtatta tttctataaa
    15841 aatttaggag aataaaacga ctagcaatat agctgtgaaa tcaaatatca catgaactgc
    15901 ccaacttgta atgatcgagt tgcttttaat ggcagcttgg ttgaataaca atcttgccac
    15961 cccttgtatc aaaaggatgt gtgctacagt gtgtaaaata tttccattat cataagtact
    16021 gtaatggata aatccaaaga tgattgctga caagaaacta gcgacaggaa tgctgaactt
    16081 actagaaaaa atagcgagaa aatacactga gaacaattct tctccaagta tcatgatagg
    16141 caaaataata aataataacg ggctgaaagc ctcatttatt ggattgcctg ttaaacccca
    16201 tttcaaaatt tgttgcaaaa ataccgagac tgcggcactg attactacat tgataaaaaa
    16261 atatttggct atatttttga caggagcgac aggtttcgag aacatttttt tcgtatcttt
    16321 tttaccaaaa acaagtgtaa atgctataaa tccagtgata gttaaagaaa aaatgctaat
    16381 aatggatggc gcaaatagca accctaacaa accgagtaca acgacaatag tgcccaatat
    16441 ccctttttta agttctattt tttttcctaa aatgttattc atgataataa ctcctactat
    16501 tcagtttttg aagatagagt cagtatacat gaagagttaa aataggcaat gtttttttat
    16561 ggatatttgt attgctaaaa atttatctta tatattcatt ttgattatac tacttttatt
    16621 tgtaaaaatt ttctagcaaa accaagtgct tgcaactgat taagcgtaca attttttaga
    16681 tgttccgagc gtacttcaat catttcaaag gagttgctac ttaaatcgat attttttaaa
    16741 tcagtatcaa aaaagctagc attttctaaa tcattagtag aaaacattat tttagtgagg
    16801 gaacagtcta caaaatctgc gcttgataag acagagtgct caaaggtact ttcttttatg
    16861 tttgaaccag ataaatttac atagtccatt ttacaattct cgaataacgt gttcccaata
    16921 taactttcca tcaatttagt acctgttaat ttacaattga caaatttcac gcgatgcaac
    16981 atgctttttg tcaatataca gcctgaaaaa tcacagtttt cgaatataca gtcggtaatc
    17041 tccattcttt gaaaatcatt ggaagcaaaa aatgcatact tgaaaataga tttgtaaata
    17101 attggatggc agattatttg gttttcgatg acctcttttt gtgaaaggat attatacagt
    17161 tcaaaatctt cgttttcata gatatgaaaa aaggatcctt tattcaagct tgcttcatta
    17221 actttaggaa aaatcatatt taattacctc cattttcata aagtcatatt aacaaaagct
    17281 aaaccaactt acattagcag aaaatgagat aggttttcgc ctttttcgat aacgatagtg
    17341 tcgctatctc ttgaaacgtt cttagaattg ccctgagaga cacaaattag gcgtaattct
    17401 aataaaaatc ttagaataaa aatttttact gatttaattt agaatgtttt taaaataaaa
    17461 atcgttgcca taacagtgta ttgaaaggtt ttaacaatcc agtaatgatt taaaaaaatc
    17521 tagatgtagc gtatactttg tttatagaat gtagtgggaa gaaatatatt tttgggagga
    17581 aatcgtgatg tctaaaagtg aagaaataga aaacatggta ctaaaattat atgatctcgt
    17641 tttaaatcca gagatcaaag aaaaggaacg tatacttttg atagacgcaa agacaggctt
    17701 agaaaaaggt cagtattatc ctaaagtcat aaataatttg gaacgtagtt tacgtccgtt
    17761 agcaatcagg ggagaattgt ctaaaccagt atcaccgttt tatatggaga tatcaacaat
    17821 aggaaaattt gaaaaagaat taggtcgagg aatggcttcg gcaccgatta cttttgggca
    17881 tttataaaaa cgagttattc atctcaatga attaaaaagt atagtcaatc tcataatgca
    17941 ggctaggttc atttatttga acagagtctg tattttttta ttctaaataa agaaacagat
    18001 gtttctttat attgtatttt atcctttaat taacacaaaa acagctagta taaactaata
    18061 atgttaatta aaagtgtatt ttatgaaact atcgttattt attaatgttg catttttgta
    18121 agttaaaaat tggaaatata gattgaaaaa atgaaagcaa taagtaaaat aaaatgaata
    18181 tatgcgaaaa aataatttac attaggaaaa accttgtaaa aacagttttt tggcatattt
    18241 attttttata aatatttgta aaataactat caatttttta gttaaaagat tggaaatgag
    18301 tgggggagga attgaagaaa ggatttttga gagatgatat agtaggtttt atttttagtt
    18361 aaaatagggg agatagaaaa aatgaaaaag tgtagaaata ttattttatc aatgttattt
    18421 attattacta atataacatc actgattcct gttcatgtct atgcggatgc aggcagagat
    18481 atcagcagta atgtcacttc gttgaccgtg gacccaacga atattacaga tggaggaaac
    18541 ataaaagtaa aattctcgtt tgacgaaaaa aaacaaaata tccaaccagg tgattatctt
    18601 tggatcaatt ggccaagtga aggaaatatt cgcggtgaag gattccaaaa agaaatccca
    18661 ttaatgattg aaaataaaaa tgttggaact ttaacggtca gaaaagattc tgcgcaggtt
    18721 gtgtttaatg aaaatattaa aaacctagac tcagtagaag gttgggggca atttgagata
    18781 caggccagaa acgtaaccga taccggtgaa gaaaatacgg gaccattcac cgtgacgagc
    18841 ggtgataaaa cagctactgt aaatgtgaca aagccagctt ctggttcttc ttctagcgtt
    18901 ttttattata aaacaggaga catgctacct gaagatacta agcacattcg atggtttttg
    18961 aatattaaca ataacggcac ttatgttgaa caaccagtta aaatcagtga tgaaatccaa
    19021 agtggacaaa gattagatcc aagtacgttt gaaattaatc aaatacactt aggtgaacag
    19081 aaggtttata gaggagaaga gggaatccaa caatttttac aagatttccc cagcgctaca
    19141 tttaattttt cagtaactga taattacatt gaaataacta taccaaaaaa ctttgtcaat
    19201 cttaggaaaa taatggtgag ttataagacg atcatagaaa acccagaaca aataaatttt
    19261 gagaatcatt cggaagcttg gtttaaagaa tttaataaac ctgctgttga tggagaaagt
    19321 ttcaatcata cagttaaaaa tatttcagct tctggtggag tcaacggtac agttagaggc
    19381 gaattgaaga ttttcaaata tatcaatgac acagagattg gtatcccaaa tgtgactttc
    19441 gaattaagac gagcagatga acagcctatt caaggacagt ctagtatcct gttgacttcg
    19501 aatgaacagg gagaagctag tatcaaaggc ctgcaagtag gagactatgt tgtaaaagaa
    19561 aaagaagcac ccaattggat tgattttgat ccactaagtt caaatgaact caaattctcc
    19621 ataaacgaaa atgatacaga gggagtcagt ttacctattt ataacaagaa aaaggttacg
    19681 aacatcacag caactaaaat ttggaacggt ggaaccactc caagaccgag tatttatttt
    19741 aaattattca gagcaagtac aaacaattgg gaaccagttc ctgatgcaga aacaaaacga
    19801 ttagacaatg gaataacttc agtgacttgg gaagatatcc aacagtatga tgatagtgga
    19861 aacgaatata cgtttaaagt gcaagaagta gatcaaaacg gaaatgatta tgtcccttca
    19921 ggttatcaaa aaattgaaaa cgggctagtc gttacaaatg agaataaaga agtcatttca
    19981 gtctcaggac aaaaaacatg ggaagacaat gagaaccaag acggcaaacg accgacgacg
    20041 atcacagtaa atctattagc cgacggtcaa ccgatccaac acaaagaagt aagtgaaaaa
    20101 gatgattggc gctatcgttt cacaaatctg ccaaaataca gagacgggca agaaatcatc
    20161 tatactgtaa cggaagacaa cgtgcccgaa tacagtacga cgattgacgg gtataacatc
    20221 aaaaacagtt atacaccgga aaaaacaaat atatctatac caggtagcca tataacaccg
    20281 tggaaaaatt ttccagagaa gacagagaga gagaaaatta gaaatctatt ctctcaaaaa
    20341 ttgcaaatat ttgctcatac aggagaatcc agcgaacaaa gaagcaatta tattagtaag
    20401 agagctgtac ctaaacagat aacaaataaa tcaaaaagca ttcttcctaa aacaagtagt
    20461 aaaaaatcta gttttgctgt aatcattggt ttattgatag taactatctg tgctgggata
    20521 ttcttacaaa aatataaaaa agtttagtta gaatataata ttttttgtta aatatgactg
    20581 aaatcaaaag aataaaattc cgatttataa tcgaaaaaag aagcattttt atatatgctt
    20641 cttttttcgt agaatcaata aatatggatt tggctaacta tggaagaata ctcgtattag
    20701 ttttcagcgt tcatactagt tgttacattg tttgattggc caaaagaatt tctgatatat
    20761 tttgtgctaa ataaagaaaa agacgcttga attgggaaat aagaaaacta ctctatcatt
    20821 acaaattttc ataaactggc agatgttcta agtaaacaag tatcttttca aagtcggaaa
    20881 aatccataat caacgtagtg gtattgatat ttggatgaaa gcctacggta tcttgacgat
    20941 caatagcagc atcgatcacg acttggattt ttttctcttt gtcgtgcatc aatgctaatg
    21001 gagtcactgt acctgctgga acgcctagga ggtcaggaag ctgttcttca gaaacaaaag
    21061 ataagcgctt ttcttttaat tgttcagcta gttgttttaa atcggcgtgc ttttcatcag
    21121 gcaagatgac aagatagatt tgttttcctt ttcttgattt caataataga ttttttactt
    21181 gcggaccagg tagggaaaaa gggacatttt tgactgacgt aatcgcagga tgatcgactt
    21241 tttgaaaaga gatacccagt ttttttagta gttcataagc ttcttgttcg gttgcacgac
    21301 tcatcgcgca tcaccctcct ttttttatta gtgtatcata aaaaagagtt gacaaatgaa
    21361 aaataatcat gtaaattaca cgtaaagtta aaacaaatga catcgaaaag aagagtagcc
    21421 gttaggtgtt tttagagagt ctctggttgg tggaaagagg cagcagttaa ccgtgaaaca
    21481 catcttggag tcgattttct gaagcgtata gtaggaaaat ccggggagcc cgttacagct
    21541 gcggtcgttg ctagatgacc agataaggct ggcttttccg tgaggagtcg gtaaaaaaag
    21601 gtggaaccac gtgattaacg tcctttgatc ttcggatcaa aggacttttt gttttcatct
    21661 gaacggcaac gactgtgtga ggttttttct gcaaggaaaa aataaacaga ggtggaacca
    21721 cgtataatac gtcctcttgg catttgccaa gaggattttt ttattttaaa ggaggaaaag
    21781 aagatggagt atttgattga agttatgccg caattattag taggagcact cacaacattg
    21841 aaattatttt tatttacctt gattggctca ttaccattag ggattgtttt agcattagga
    21901 ttgtctttgc attttaagcc gctacgctac ttgcttcaaa catatgtatg ggttatgcgg
    21961 ggaacaccgc tgttgttgca actgattttt attttttatg ggttgccgac gattgggatc
    22021 gtttttgatc gtttcgaagc agcactcatt gcctttatct taaactatgc agcttatttt
    22081 gcagagatct ttcgtggagg gatacaatcg attcctcaag gtcaatatga agcagcgcaa
    22141 gttttgcaat taagtccctt tcaaacggtg acgaaaatcg tcatcccaca agtgacaaag
    22201 attgttttac cttctgtagg gaatgaagtt atcaacttgg tcaaagattc ttccttgatc
    22261 tatatattag gtttaggtga cgtaatgcgt gctgggaaaa tcgcgatgga acgcgacgcg
    22321 actttactgc ctttgctagg cgtggcaatc atctatctta cattgactgg tattctaaca
    22381 atcgtaatga aacaagttga aggaaaatta aattattacc gctaactgat aggaggaaga
    22441 aatatgattg aattgaagaa agtgaacaaa gcatttggtg aaaaaaaaat aatcaaagat
    22501 ttgaatctaa tcattccaga tgggaaaaca ttagctatcg taggtccttc cggtggcggt
    22561 aaaaccacgc ttttacgtat cttggctggc ttagaaagtt ctgacagcgg agaattttat
    22621 ttagacggtg taccgttcaa cccattcgag cttaaaatga aagaacaagt tgtaggagtc
    22681 gtattccaag acttccagct atttccacat ctgaatattt ttgaaaacat taccttagca
    22741 ccaaaaatgg tattgaaaca gacaaaagaa gaatacacca aaaaagcaga agaattagcg
    22801 gcttcattag ggattagtga tttattgaat atctatcctt atcagctttc tggcggacaa
    22861 aaacagcggg tagcgattgc cagagcattg gctatgaatc cacgggtatt ggcttatgat
    22921 gaaccaacaa gtgctttaga tcctgaatta cgccagcaag tcgagcgttt gatcctatca
    22981 ttgaaagaag atggggtaac ccaaattatt gtcacccatg atttagtatt tgcagaaaat
    23041 gtcggtgatc aattactaaa agtttcccca attcattaag aaaggagaag atagagatga
    23101 aaaaaaccag ttttctattc gctttgatcg caggtcttct tctttttgca ggctgttcga
    23161 acaaaaaaac ttcagcagat aattgggcga ctatcaacga agagaaaaaa atcgttatag
    23221 gtttagacga tacatttgtt cctatgggat ttagagataa agacgggaag ctcacaggat
    23281 ttgatattga tttagccaaa gcagtctttg aacaatatgg gattacggta gactttcagc
    23341 ccattgactg gtcaatgaag gaatttgaac tgaacaatgg aacgatcgat ttgatatgga
    23401 acggctattc caaaacgccg gcaagagaaa agaaagtgca atttacaaaa ccttatatgg
    23461 aaaacgatca agtgctgatc acacctaaag aatcaggaat cacaaacttt ggacaaatga
    23521 ataataagag attaggtgcg caaaatgggt catctggtta tgatgtattt acgaaacaac
    23581 cagaagtatt aaaagagata gtcaaaaacc aagatgctgt tttgtatgat agttttaatg
    23641 aagcattgat cgatctgaaa agcagacggg tcgatggtct gctgatggat aaagtatacg
    23701 cagactatta tttgaaacaa agaaacgaac tagaagactt caacataaca aaaggttctt
    23761 atgagagtga ggattttgca gttggtgcac gcaagtcaga tagtacatta gtgaaaaaaa
    23821 tcaatgaagc cctagatcaa ctagagaaaa caggtgaatt ccaaaaaata tccgataaat
    23881 ggtttggcga agatgttacg ccgagaaatt aacaaatagg ggactgtgac aaaagacgtg
    23941 tcacagtccc tttttccgaa taaacagtgt tctcctgcca actccttgtg actcggagct
    24001 gaatggcagg ctcacaacct cttggtaaac ggtgttcaaa agccagtttt tcggtattaa
    24061 gccaaattta tgcaaaaatg tagaaagcca ttttcacaaa atttttctta ctactcgaaa
    24121 ctaagcgact ttttcacaac ctcctttaca taattttatt ttgttgtgga aggggtttcg
    24181 tgttattcta aaagaggaac gattgaaggt tataggaaag gaagagatga atggaacaca
    24241 aagaacttac ctcatttcca aaagattttc tgtggggctc tgcttctgca gcgtatcaag
    24301 tagaaggagc ttggcaagaa gatgggaaag gagaatcagt ctgggatcga tttgtacgga
    24361 tacctggaaa gacatttaaa ggaacgaacg gtgatttggc agtagaccac tatcatcgtt
    24421 ataaagaaga tattgcttta atgaaagaac aaggtctgaa agcttaccgc ttctctgtag
    24481 cttggacacg gatttttcct aatggacgag gagaagtcaa tcaagctggg ctcgcttttt
    24541 atgagagatt gatcgacgaa ttgattgaaa acgatattga acctatgttg actttatatc
    24601 attgggatct tccacaagca ttgcaagatg aatataatgg ttgggaatca cgtcagatca
    24661 ttgaagattt cactcattat gcagaaacat tatttgaggc attccgcggg aaagtccatt
    24721 actggattag tttgaatgaa caaaatatct tcacttcatt aggttatttg ttagcagcac
    24781 atccgccagg tgtgacagac ccgaaacgaa tgtatgaagt taaccatatt gctaatttag
    24841 caaatgcatc tgtcatcaat aaatttcacg agttagaaat gcctggaaaa atcggaccaa
    24901 gctttgcgta tacgccaaat tatccaattg acagtaatcc tgaaaatgtt ctggctgctg
    24961 aaaatgcaga agacctgatg gccaattatt ggatggatgt ctatatgtgg ggaaaatatc
    25021 cgattgctgc catgaggttc ttagaagaaa aaggatgggc accaacgatt gaagctggcg
    25081 atgcagaatt gctagaatct gctaaaccag attttcttgg gatcaattac tatcaaacgg
    25141 cgacgaatgc attcaatcca ttaaacggag ttggtgctgg aaaaatgaat acgacaggaa
    25201 aaaaaggttc atcagaagaa actggagttc ctggaatgta taaaaaagtt gagaatccat
    25261 ttgtcgaacg aacaaattgg gactgggaga ttgacccaga aggattaagg atcggactgc
    25321 gtcgtatcac aagccgttac cgcatgccgg tactgattac ggaaaatggc ttaggagagt
    25381 atgacaagtt gacagaagat aaacaaatcc atgacgacta tcgaatcaat tacttacaaa
    25441 gccacgtcaa agccatcaaa gaagcaattt cggatggagc agaagtccta ggctattgca
    25501 cctggtctta tacagatttg cttagctggc tgaacggtta tcaaaagcga tatggatttg
    25561 tatatgttga tcaagacgaa acacaagaag gatctttgga acgatataag aaagacagtt
    25621 attactggta ccaaaaactg attgaagaaa atggagagaa cctttagttc acatacttaa
    25681 aacaagaagg tacggctgga tatggccgtg ccttttcttg ataaaatcat ttagaaatta
    25741 agaaaaactg taaaataagc tgaaaaatga aagaaagcgt cagttctttc aaacaaaact
    25801 ttagttccct tacttttttt tgtataatga aacttgatga aatgagggat aataaatggc
    25861 acaaaagaaa cggcctacta aaaaaaggaa aaagacgaaa aaaacgaaaa agcaaaaaca
    25921 gcagcaggaa caaatgctga cgattggtgt tgggtttgcc ttgattttat ttgctgtctt
    25981 cggcttttta aaattaggtt ttttaggaat attgattgca aacggctttc ggatcattgc
    26041 aggaaatact taccaaatcc tctgtctttt attagccgta ttaggatttt ggattgtcat
    26101 taagaataca gagttttcaa ttggtaaaaa ccgacgctgg tttggcggca tactctttta
    26161 tttcggtatc ttattattgt tacatgccca tttatttggc aaactccata ctggggaacc
    26221 aaatatcatg gggacgacat gggatttgtt agccagtgat ataaaacaaa gtcaagtaga
    26281 caataacgtt ggtggtggga tgattggagc aatcctttat cattttactt acttcttgat
    26341 tgcacagcct ggaagttatt tagcagcagt gctattactg gcaggaggag cattcctgtt
    26401 cagtaatctg gaaggctatc agctgttaaa tggtatccaa tcaattggag aacgagtaca
    26461 ggaattattg gaaggtgatc ctgccaagca agctcgaaag caagcggcaa aggaagagag
    26521 aatgaaacag cgcgcagaag cgaaagaagc aaggcgctta gctgcaaaag aagctgcaga
    26581 aaaagaagct gcagaatatg agaagaaaaa agcggtgagc cagcaaaggg aaaatactgc
    26641 tgatgaatgg caggaaccag aaaatacaga gccggagcag ctaagttttg ttccaatcga
    26701 cagttttcaa gaaaatatcc atcctgcgaa tctagagaaa ccagtaccag atacaccaaa
    26761 acagaccaat acagcagaag gtttttcaga tgagttgcca gaggatgacg gtacctcatt
    26821 agaatttgag attgaagcag aacaggaaaa tcaagactat gaattaccga cagttgattt
    26881 gcttgattct ataccaactg tggatcaaag tgatgagtat aaaaaaattg aaaaaaatat
    26941 cggcgtatta gaacaaactt tccaaagttt cggtgtcgat gccaaggtcg tcaaagccag
    27001 cttaggacca tccgtcacaa aattcgaagt ccagccggct gtaggggtaa aagtaagtaa
    27061 aattgtgaac ttaacagatg atatcgcgct tgctttagcg gcgaaagatg tccggatgga
    27121 agcaccgatt ccaggtaaat cactgattgg tattgaagta ccaaatggaa agatcagtat
    27181 ggtttccttt agagaaatca tcgaagcaca accaaaccac ccagataaat tactagaagt
    27241 acctttagga cgtgatgttt ctggacgggt acaaacggct gatctttcga agatgcctca
    27301 cttactcgtg gctggttcga ctggtagtgg gaagtcagta gcaattaatg ggattatcac
    27361 aagtatatta atgcgtgcta agccccatga agtaaaactg atgatgatcg atccgaaaat
    27421 ggttgaattg aatatgtaca acggcatacc tcatctgttg acgccggtcg tgacgaaccc
    27481 tagaaaagca gcgcaagcct tacaaaaagt agtacaagaa atggaagaac gatatgaaaa
    27541 attcgcggca accggagtaa gaaatatttc tggttacaat gaatttgttc aacagaaaaa
    27601 cttggaaaac ggaacgaaac atccaacctt accattcatc gtagtgatcg tagatgaatt
    27661 agctgatttg atgatggtag ccagcaatga agttgaagat gcgattattc gtttagcgca
    27721 aatggctcgg gcagcgggga ttcatatgat cctagctact caacgtccaa gtgtggatgt
    27781 tatcacagga atcatcaaag caaatgtacc ttccagaatg gcatttgcgg tatcaagcgg
    27841 tacagattct cggacgatca ttgattctaa tggggcagaa aagctcttag ggcgaggaga
    27901 tatgctattc ttgccaatgg gtgagaataa accgatccgt gtgcaaggag cattcatttc
    27961 tgaccacgaa gtagaacggg tcgttcaatt tgttacagat cagcaagaag ctcattatga
    28021 agagaaaatg atgccgacag atgaagttga aacgacaggt gctccagaac agccacaaga
    28081 tgagctgttt gaagaagcaa aagcacttgt cgttgaaatg caaacggcaa gtatttccct
    28141 tctccaaaga agatttcgga tcggttacaa ccgagcagca cgtttagtag atgaactgga
    28201 agctcatgga gttgttggcc cgtcagaagg aagcaagcct cggaaagtat tcattgagca
    28261 ggaagaaaca tcagaaacgt tgccggacga taatgacatg taaaacttgt gtgatgaagg
    28321 gttgaaaaac gaataaccaa taaaaagaca aggcatgatg ataccaaaag aaaaaatggt
    28381 ttttttccat cttttctaat acggtatgat gtcttgtctt tttagttttt gtgagattaa
    28441 agttctattc gatttatttg tgaagtattg cattaaggaa atgaatcatg tatagtatgt
    28501 agcgaaactt tgagaaaaag agggaaaata ctttggaaaa acagtccatt tatggcttga
    28561 cgaatgaaga attaatcaat tggtttatag aaaacggcga gaaaaaattc cgagctgccc
    28621 aagtttggga atggttgtat caaaaacgtg taagtaattt cacagaaatg acgaatctat
    28681 cgaaacaatt gatcgaaaaa ttatcggagc attttatcat caatcctcta aaacagatgg
    28741 tcgtccaaga agcttcggat ggtacagtaa aatatttgtt tgaactccct gataaaaaca
    28801 tgattgagac tgtactgatg agacaagaat atggcttgtc agtttgtgtg acgacacaag
    28861 taggatgtaa tatcggctgt acgttttgtg caagcgggct gctcaaaaag aaccgtgatc
    28921 tgactgctgg agaaattgtt gcacagatca tgatggtcca acattatttt gatgagcgca
    28981 atcttggcga acgcgtttca catgtcgttg taatggggat cggtgagcca tttgataatt
    29041 acgacaatgt aatggacttt ttgcatatca tcaatgatgc caaaggattg gcaattggtg
    29101 ctcggcacat tacagtttcc actagtggat tagcacacaa aatcaaggaa ttcgctaata
    29161 acggcttgca agtcaatctg gctatttcct tgcacgcgcc gaataatgag gtgcgaacat
    29221 cgatcatgcg gatcaaccga agtttcccaa ttgagaaatt gatggaagct gtggatgagt
    29281 atttagagaa aacaaaccgt cgaatcacgt ttgaatatat catgttgaat caagtaaatg
    29341 atagaccaga gcatgcgcaa caattagcag atctattaaa agataagaaa aaattagcat
    29401 atgtcaactt gattccatat aatccagtca gtgaacatga tcaatattct cgcagtccaa
    29461 aagctgatgt attgagattt tatgatgtat tgaagaaaaa cggcgtaaac tgtgtgatac
    29521 gtaaagaaca tggtacagat attgatgcag cttgcggaca attgcgaagc aagcaaatga
    29581 aaaaaacagt tgccaaataa tcgtatccta ctcgtttttt caattaccat aaaaggagca
    29641 gttttcttaa ttaaggaact gttcaactta aataagagaa aagattctat agcgaaagct
    29701 ataaagcttt ttttgacaag aaaaaccctc atcaagcaaa gaaatgtcct caatttgatg
    29761 acagcctgct tgatgggggt tttagcaatt atttaactga ttttcttata tccttgctgg
    29821 ctttcttgtg tagcatgata agtttctacg tcaagaatgg cctgtttaaa tttttctcgg
    29881 gtgatttcat aaggcacatg tttaatatca tttgttgcca tggctttatc taagattgct
    29941 tctaaatcgg tcgtgacatt gagattcatg tcggttaacg atactggaag ttggttcttt
    30001 ttcataaaca catagatttt atcaaacaaa tcgaactgct gatccatcat caataaggtc
    30061 agtacaccat aactgacaga tgctccgtga aggtatccct ccattttttc tagaacagtc
    30121 gtaccgtaat agaatgagtg tgccatagca gaattatagt tattgttaac taaaacagaa
    30181 accaatccgg tagtaacaat gatatccgaa acgacttgtt caattgcata tgagggacga
    30241 tcgtcggcac tatctttcaa tgcttgcgta ccataagtca agagacgatc aatgcacatt
    30301 tttccgattt ggattcctaa tctatccgtg tagcctagat catcgccacg agcagaaaaa
    30361 gtagattcga cttctttgga taaagcatcg ccaatacctg cccataagta tttatcaggt
    30421 gcttcggcaa taattgctgt atcaatgaag gtgtgtacag gtggttttga aggaaagaag
    30481 agtccgtcca ttacgccttc ttcgttatag atgacacata ccgcagtgac gggcgaacag
    30541 ttcgaaccaa tagtgggaaa ggtgaagact ggtttagcta gtttttcacc aatgactttt
    30601 acagtatcgc aagcacggcc accaccgact gcaaacagga cgtctgcttt ttggacactt
    30661 tcatgctgga tcaactgttc aatatttcca taagttgaat tacccccgta ccagagactg
    30721 gcgacaacct ctatttcctg tgtcaaagct acttttattt tgttttctgc ctttgaaagt
    30781 gcagtcttcc ctccaatcag cactactttt gtcccatatt ctttgacgat tccatttgct
    30841 ttttcatacg catctgttcc aatggtataa tttggtaaga aaacactttg actcatattc
    30901 atttccttct ttcttcgttg aaacgggtta aaattttaaa gagtgatcga tctgactgcg
    30961 gctgtagatg gagtagaggt gaacctaaga caggataagt gatgaataag gtggcatgaa
    31021 caccttgaaa tcatcaataa gtatcctaaa aacgaacaag tacaaaaaca ttgaaaacga
    31081 caataatgaa tttttgttcc tcttagtatt tctaccgatt ccctttgctt ttttgtaatt
    31141 atctaaaaat tctaaaaatt aagattatta tatgaaaaca ggttttattt gtcaattcat
    31201 aattggtttt ttttaaagca aaagataatc tatatcatga tgaacaaaca gagttttttc
    31261 ctccaattga tggctttcct gatctttcct attttgaata aagtgtttct gtataatttt
    31321 ttattttata agtaagataa ataatgaaag aatagagata ctgattggta gctaaagatt
    31381 tttgagcgag aacatttcgt tttttcaaaa ggactgttag aataagcaag aacaaggggg
    31441 aagacgtatg ataatcagtg aatttgaccg taataatcca gtattgaaag atcagctttc
    31501 tgatttactg agactgactt ggccggaaga atatggagac agctcggcag aagaagtaga
    31561 agaaatgatg aatccagaac gaatcgcggt agcagcggta gaccaagatg agttagtagg
    31621 atttattggt gcaatccctc aatacggtat cacaggttgg gaattgcatc cattagttgt
    31681 agaaagctcc cgacgaaaga accaaatagg tactcgatta gtcaattact tagaaaaaga
    31741 agtagcttcc agaggaggaa tcacgattta tttaggtacg gatgatttag accatggaac
    31801 aacgttaagt caaacggacc tgtatgagca tacatttgat aaagtggctt ccatccagaa
    31861 ccttcgtgaa catccgtatg aattctatga aaaattaggt tataaaatcg taggtgtctt
    31921 accaaatgca aatggctggg acaaaccgga tatttggatg gcaaaaacga ttattcctcg
    31981 accaaattct caataataaa aagaggttgt gacagaagta atcagcttca agaaataaga
    32041 aggaatttac gaaaattact tcttgaattt ttgtgaaatt ccaacttatt tccgaagaag
    32101 ctacttttgg aacaccgtgt accagaggtt gtgaaaaagt cgcttagttt cgagtagtaa
    32161 gaaaaatttt gtgaaaatgg ctttctacat ttttgcataa atttggctta ataccgagaa
    32221 actggctttt gaacaccgtt tattcagata agggactgtg acaagacttt tgtcacagtt
    32281 tctttttgtt tattcttttt tatctttgta tggcaataat agacaatata acgaaaatta
    32341 tttaatggct tttggaagac catggaaaac cttgtacaaa gctatttttt ctgaaaaatt
    32401 ccttgaaacc tcacgaaaaa atcattattt tatgaaaaag acaaaaaaaa gtgttgattt
    32461 tttaataatt attcattaaa ctcttaaaca acttcagaaa atattaatta ttctgaaaat
    32521 tccaataaag gggtacgtaa aatgaaaaag aaatttacat ttggtttggt tgcggtatgc
    32581 ggccttgtac ttgctggatg ttatggcggc agttcagcca caagcagtag ttcagcaaaa
    32641 agcggttcag cagatggagg aggcgtattt aacttagtcg tgcctcaaga aatgcctaca
    32701 gctgacttat cagttgcaac agatacaatc agttttacag cattgaataa cgtttatgaa
    32761 ggaatttacc gtcttgatga agacagcaaa ccacagccgg caggagctag cgagttggca
    32821 gaagtcagtg aagacggatt aacttacaaa atcaaattac gagaagacgc aaaatggtca
    32881 aatggtgatc ctgttacagc agcggattac gtttatggct ggcaacgaac agtagaccca
    32941 gctacagctt ctgaatatgc ttacctgtat gcgccagttg aaaatgcaga agacattaca
    33001 gctggaaaga aagataaatc agaactaggg atcaaagcag ttggtgacta tgaattagaa
    33061 atcaaattga cgaaacaaac accatatttc caatatctgc ttgctttccc atcatttttc
    33121 ccacaaaaac aatccgtagt ggaagaaaat ggggatgcct atgcatctgc aagtgataaa
    33181 gctgtttata atggaccatt cacattagaa gattttgatg gaccaggaac agatacagaa
    33241 tggacttata agaaaaatga tcattactgg gacaaagata cagtaaaact ttctgaaatc
    33301 aaagtcagtg tagtaaaaga atcttctact gcattgaact tattcaaaga tggccaagca
    33361 gatgacgtga tcttgtctgg tgagttagca cagcaaaacg caaacgatcc agcttatact
    33421 tctgttaaag aagcgcggac aagctatatc gaattcaatc aacgtgaaaa gaattcacca
    33481 ttcaacaatg tgaacctaag aaaagctatt tcttattcta tcgatcgtga agctttagta
    33541 aaacaagtac taggtgacgg atcagttgtc tctacaggat tgatcccatc agatatggta
    33601 aaaagtccaa caacgaacga agactttgca aaagaagctg gaaaattagt ttcttatgac
    33661 aaagataaag caaaagaata ttgggaaaaa gcgaaaaaag aattgggcgt tgattcttta
    33721 gaatttgatt tgatggcttc tgatgatgat tcatcgaaaa aagtaatcga atatgttcaa
    33781 aactcaatcc aagaaaactt ggatggcgta acagtcaaac caacacctgt tccattctct
    33841 gtacgtcttg accgctcaac ttcgggtgat tttgacgcag tactaggcgg atgggctgct
    33901 gactatgcag acccaagcag ctttactgat ttgtttgtca caggtaattc atacaaccgt
    33961 ggtcgctgga gcaatgcaga atatgacgaa gcagttaaag cagcttcatc aacagacgct
    34021 ggcgatgaac aagcccgttg ggatgatttc caaaaagcaa tcaagatcat ctctgatgat
    34081 atgggtgtcg ttccggtgta ccaaaaagca gaaggtcacc tagtgaatga aaaaatcaaa
    34141 ggtatcgttc accatgcggc aggcgcttca tgggattaca aatggacata cgttgaagaa
    34201 taatcgttaa taccgtgagc atgagaaaaa acgaggctgc ggcaaatgtc gcaacctcgt
    34261 tctcatattc acttatccta acaaagaaaa aagcatgaaa atagcagaaa gagcaattag
    34321 tattccggca atgatcagcc aaaagctgta cataccgtag ctggcagacg agagcgtgga
    34381 aaattctggt tttttctttc ggttccttgt tcgtgcaaga tggaccgatc gctgaaaatg
    34441 atcgaagaaa cccgaagaaa agacccataa aaaaccgccg ataatcagaa acggcaatga
    34501 ccataagaat agatcattag ataattgaat gagtgtaaag gaatggttga tgagattttt
    34561 tattaaaata accagaatca gtagaaaagc tactgcgtag gggatagatt tttttttcat
    34621 ttgattgctc ctttattttt ggttcattat ctaataatgt agcgaaacat ctgtcagaag
    34681 tcaaaagcta gggggaaaca ttagtgaata gttatatcaa atatgtatta aaacgtgtct
    34741 ttttcatgat catcacgctt tggttaattg caacaatcac ctttttcttg atgcaattgc
    34801 tgccgggcac gccatatacg aatcaggaac gtttgagtcc tgaaacaatc gagatgctaa
    34861 ataaacaagt cggtttggat aaaccagtta tcgtacaata tgggatttat ctttctaatt
    34921 tgcttcaagg agattttgga atttccttcc aatttaaaaa ccagccagtc gcacatttgt
    34981 tagctggaag aatcggacca tccttgcagt tagggttaca ggcaattatc tttggaacag
    35041 tcctagggac gattttagga acgatctctg ccatgaagca aaatacatgg gcagatacat
    35101 cttctacact cgtagcgata ttaggtcgtt ccattccaaa ctttgtattt gctgttttat
    35161 tacaatatat ctttgcaatc aaattacaag ttttgccaat cgcaaaatgg gatggctttg
    35221 tgtacacaat cttaccaaca attgcgttgg ccatgtcgcc gcttgctgac tctgctcggt
    35281 ttatccgtac ggaaatggtg gaagtactgc atagtgatta tgtggaatta gcaaaagcaa
    35341 aaggattgag ccgttgggaa atcgccttta aacatggtct tcgaaatagt ttgattccat
    35401 tgatgacttt attaggaccg ttagctgtag cattgatgac cggatcactg gtggtagaaa
    35461 atatctttgc tattcctggt atcggggaac aattcgttaa gtcaatcaca acaaatgatt
    35521 atcctacgat catggctgta acgatccttt actcatttat gctgattttt gttattttga
    35581 tcgtggatct attgtacggt ctagttgatc caagaattcg tgtttcagaa gggagccgag
    35641 gataaatgga aatgatacca aagcgttatg aaacagttgc agatatccct gcggatgaat
    35701 ttcttccatt acaaaaaaat accgaagaag aacgtgaaca gattactgca ccttctttga
    35761 attttatcca agattcatgg cgccgtttaa agaaaaacaa agctgccgtt atttcaatgg
    35821 ttttactatt ggtcatcatt ttgatctctg tgatcacaat ctttgtttct cctcatgatc
    35881 caactgccca aaacgtggct tatatcaatt tgcctcctcg tattccggga atcaatatcg
    35941 atggattgaa tggaaaagca atggttggtg gtgaacttgt tgataaatat gctcaagcaa
    36001 acgtcccttc aaacgtaaat ttctttttag gaacagacgg tttgggacgt gatgtattaa
    36061 gccgcttatt tatgggaatg agaatctcgt tgctgatcgc atttattgct gcattactag
    36121 atgtaacgat tggtgtagct tacgggttgg tttctggttt gttaggcgga cgtgtcgata
    36181 acgtgatgca acgttttttg gaaatcttat caggaattcc aaacctcgtt gtcatgattt
    36241 tgatgttggt cgtttttgaa ccaggaattt tttcaatcgt ggctgctatg gccatcacaa
    36301 actggatacc aatggcacgt atcgttcgtg cacaaacaat gaaattaaaa gatcaagaat
    36361 atgttttagc tggattgaca ttaggtgaat caagaatgaa aattgcattc aaacatattt
    36421 tgccgaatat ctctagtgtc attattattc aaatgatgtt tagtattcca tctgctattt
    36481 tcttcgaagc ctttttaagc tttatcggtt taggtcttac gcctccgtca gcttcattag
    36541 gaacgatgtt gagcgaaggg tacaagacat tcctgtatct gccttatcta ttatggattc
    36601 cggcagtaac tttatcggtt atcatgattg gctttaactt acttgctgat ggattgcgtg
    36661 atgcctttga tcctaaaatg aaagagtgaa gacgatgacg aaaattttag aagtgaaaga
    36721 cttagaaatc tcttttgata cgtatgctgg aaaggtacga gcgattcgcg gtgtcaattt
    36781 tcatttgaat aaaggagaaa cattggcgat cgttggggaa tctggaagtg gaaaatcagt
    36841 gacgaccaga agcatcatgc gcttgctgtc aagcaacgcc aatatagatg ctggtcaaat
    36901 cctctttaaa ggtaacgata tcgttggaaa atcagaaaga gagatgcaaa aaatccgtgg
    36961 taaagaaata gcgatgattt tccaagatcc aatgacctct ttagatccga cgatgcccat
    37021 tgggaagcaa gtcgctgagt cccttagaaa gcataataaa gtttcaaaaa aagagggaca
    37081 aaaagctgca ttagaattgc ttaaattagt tggaataccc gaagctgaga aacgtatcaa
    37141 cagttatccg catcagttct caggaggtca gcgtcaacgg atcgtgatcg cgattgcact
    37201 ggtatgttat ccggaaatcc tgattgctga tgaacctaca acagcgcttg atgtgactat
    37261 tcaagcacag attttggagc tgctgaaaga aattcagaca aaaatcgata catcaattat
    37321 ctttatcact catgaccttg gtgtagtagc gaatgtcgct gatcgtgtcg ctgtcatgta
    37381 tggaggaaga atcgttgaag ttggaacatc ggaagaaatt ttctacaacc cgcaacatcc
    37441 ctatacttgg ggactgcttg gttcaatgcc gacattagat agtgcgaacg atcgattgta
    37501 tgctattcct ggttctccac cggatttatt gaacccgcca aaaggagacg cattctatcc
    37561 aagaaatgaa ttcgcgatga aaatcgatgc agaacaagaa ccaccatttt ttgaactatc
    37621 aaaaacacac aaggcagcaa cttggctact tgctccgcag gcacccaaag tgacaccgcc
    37681 agaagaaatc caacgtcgct gggctatctt taaagagaaa caaaaacata cttacggtca
    37741 aggaggaatt gctgatgcca aataaactac ttgaagttaa aggattgaaa cagtatttca
    37801 atgtaggaaa aaagaatgaa gtacatgctg taaatgacat cagctttcac atttatgaag
    37861 gagaaacatt cggtttagtt ggagaatctg gaagcggaaa atccactact ggccgtacga
    37921 tcattcgctt gaatgaacct actgatggtg agatattatt cgacggtcaa gatataacga
    37981 agatcaaaga taaaaaaggt ttgacgaaat tccggcatga tgttcagatg atctttcaag
    38041 atccatacgc ttcgttgaat cctcgtatga aagtcagaga tatcattgcc gaaggaattg
    38101 atgttaatgg actagctaaa tcatctgaag agcgtgcaaa aaaagtcgat gatctattga
    38161 gaactgttgg attgaatcca agccacggta ctcgttatcc tcatgaattt tcaggtgggc
    38221 aacgccagcg tattggtatt gcacgagcat tggcagtaaa accgcgtttt atcatttgtg
    38281 atgaaccaat ttctgcacta gatgtgtcga tccaagccca agtggtcaat ttgttgcaag
    38341 atctccaaaa agaacatcaa ttgacctatc tatttattgc acatgatttg tcgatggtta
    38401 aacatattag tgaccgaatc ggtgtaatgc ataacggctt gttattagag atgggaacaa
    38461 gtgatgaaat ctataatcac ggtgttcatc cttatacaga aagtttgtta tctgctattc
    38521 ctctaccaga tccagaccat gagagaaaac gcagaagaat caaatatcaa cctgaaccag
    38581 atgacggaca agtacgtcaa cttcgtgaaa tcgcaccaga acattttgtc tatgcaactg
    38641 agcaggaagt cccatattac gcaaaaaaac taaaacgaca aaaggaatct cttctggttg
    38701 ctaactagga gggacataga tgctaaaagc ttttaaattc cgtatgtatc cgacagaaga
    38761 acaaaaacag caattgattc gtacttttgg atgtgctcga tttacctata accatttgct
    38821 gaaaaagcgg cagaaaagtt ggcaacaaac aggagtagcc aatttttcgc tcacacccgc
    38881 tacattaaaa aaagaatacc cattcttaaa agaagtagac agtcttgctt tagcaaatgc
    38941 acagcttaat ttggatcggg cttttcgcaa ttatttcaag ggacgtgcca gcttcccaaa
    39001 gcttaaaacg aaaaaaagta tgtggcaatc ttatacgacc aacaaccaaa cccgtacgat
    39061 ctatctggaa aatggctact taaagttacc aaaacaaaaa gaactaatca agataaatca
    39121 gcatcggcca gttgaaggat cgattcgctc cgctacgatt tctgctcgat ataatgaaga
    39181 attttatgtc gcactacttt gtgatgtttc gccagtaaaa aaagaatctt tagctaaatg
    39241 gatcgggatc gcctatcatc cgaagacatt gatccaaaca tctcgacctc tagaagtaac
    39301 tttaccaaaa tttcaccaga cagaagaaaa gctgcaacat gcacagcgga aattgaatgt
    39361 gaaagtccgc tccgctcacc atagaaagat caggttagat caggcaagca attatcagaa
    39421 acaaaagaga aaagtaatgg atctttatct gaaacaaaag aaccagcgag aagattatct
    39481 tgaacaatta tctgggaaat tggtcaaaca atatgactac ttatttgtag aatcttttcc
    39541 aaaagaagag gcacatgctg atttttctat tcacgactgg cataaattaa taacaaaatt
    39601 gcgttataag tcccaatggt ataataaaaa atttcttttg atcaataccg acggagcaga
    39661 agaaagcaat tccgtaagaa agagccaagt agtagaaaaa atgggcagac attcggttat
    39721 caagggataa aaaatgaatg aaactgatag gagcgttagg gttagccttg ttaataaaaa
    39781 gtcttaatga cttttgtttc taggaatttt tcttttgaag aaaagctcac taattatgac
    39841 aaaccaataa aacaatagca gaaaaagttc gtacgagctt tttctgctat tgttaatttt
    39901 ttattcagaa agtttacgaa tacatcaaaa ttctgaaaca aaaaacgtaa ctcacaaaga
    39961 gttgtttttg cgttttttct tgaatgatta ggtctgaatc ttttgctcac aaccttattc
    40021 atggtgcccc ggcttgagct gatagatttt tgaaggacgg ccgattccta caggacgttc
    40081 accgatctca tcgaaatatt ggagcatagc tttcttaaaa ttggaatgat cgatcgtttt
    40141 ataatcgatc cctaagaatt tagcaaatac ttttcgagct tccgtaatcg tgaaatcttt
    40201 acctaaaact tgtagaactt gcggctcgtg ttccatttta ttgactacac ggttgaatgc
    40261 tttcaagatg atttgactat ggtcaaaagc caaagtatct ttgccagaag actctccagt
    40321 gactaaatca agcgagatag ccacttctcc gctagataaa tggatcttgt tactatgacg
    40381 ttctagtgtg aaccagcgta cttccttggc atcatctccg gcgattagcg gttcttctcc
    40441 aataaaggct aagtagctga ctgtgacgac ccagcctcgc ggatctcgat taggcgtact
    40501 gaatgtatgc agttgctcaa tattttcttt tgaaataacc acaccagttt cttcctttgt
    40561 ttctcttaag acgctttctc cagttgactc atccttttgg acaaagccac caggcaatgc
    40621 ccatgaattt cgataaggat gcccttttct ttggatcaac aaaactttca gctgatcttc
    40681 ttctttgtta tagcacatca gtacgatatc gacagtcaaa gagggcttgt catattctgg
    40741 acgttcctgt ttttgatacc agttaagaaa ttcttcttca cttgctttat gttcataata
    40801 taatttttct tcttctttag aagcaaaacg gttcatctga ccacctccat tgacagtaaa
    40861 agtacttttt accttattgt agcagactct gaaaaaaaac caaggattta cttgaaaaat
    40921 ctaggttatc atttaaatat gaaaaataaa tggaagtatg agattgaata aaaagaaaag
    40981 cagataaaac ggcaatactt tataccgctc ttcacgaatg gcaaagaagc cacaaataac
    41041 gatatatacg tcaatgataa aacgcaaaat ccaagctgct gtcataaaac tgttcaaatg
    41101 cccatggagg ttaaaataac catacatacg aatataaaaa tagctgaata ttaaatgtgc
    41161 taatgaaaga aaagcaatac taagtgtaaa aaaaagatgt ttcttctgca tgattgttcc
    41221 agtcccttac taagatagat agtctttatt ataccacgtg tgaggggaga aataaaaagc
    41281 cgttttttag tagatatgaa acaaaacaaa aacccgcatt tattcaacct attcatcctt
    41341 ttaaaggata gattgaacgt agatagaagt cgtttatcca gtctttttca ttttgaaaaa
    41401 aagctaacag catgcttttt ttatggtata ctagcaagga aacgaattcg catcatgcga
    41461 taaaggagga agagccccgt ggcagaaaag gaaacttttt atatcactac gccaatctat
    41521 tatccaagcg gcaaacttca tatcggcaac tcgtatacta cgattgcatg tgacgcaatt
    41581 gctcgttata aacggttgat gggctttgat gtgttttatc tcactggagt ggatgaacat
    41641 ggtcaaaaaa tcgaaacaaa agcagaagaa ctaggtgtaa aaccgcaaga atatgtagat
    41701 aaaatggcgg ctgatgtcaa gaaattatgg aaaacgcttg atatcagtta tgataaattc
    41761 attcgcacga cagatgatta ccataaagca gctgttcaaa aaatatttga tcgtttatta
    41821 gaacagggag atatttactt aggtgaatat gaaggctggt actctgtttc tgacgaagaa
    41881 ttctttacag aaacacaact tgcagaagtg tacaaagatg acgaaggtaa cgtgatcggt
    41941 ggtaaagcgc caagtggaca cgaagtagaa ttggtaaaag aagaatcata cttcttccgc
    42001 atgagcaaat acgcagaccg tctattggaa tactatgaag aacatcccga attcatccag
    42061 ccagaatctc gtaaaaacga aatgatcaac aactttatca aaccaggatt agaggatctt
    42121 gcagtttcac gaacaacttt tacttgggga gtaccagtca agagtgatcc gaaacatgtg
    42181 gtgtatgtat ggatcgatgc attatccaat tatattactg cactaggata tggctccgaa
    42241 gatgaaagtc tattcgaaaa atactggcct gcagatgttc agatggtcgg taaagaaatc
    42301 gttcgctttc atacgatcta ttggccaatc atgctgatgg cccttgattt gcctctacct
    42361 aaaaaagtat ttgggcatgg ctggctattg atgaaagacg gaaaaatgtc taaatcaaaa
    42421 ggaaatgtcg tttatcctga aatgcttgtg gaacgttatg gtttagatgc actccgttat
    42481 tatttgcttc gtgctgttcc gtttgggtca gatggtgtct ttacgccaga agattttgtt
    42541 tcccgtgtca attatgatct ggcaaatgat ctagggaact tattgaatcg aacgattgct
    42601 atgatcaaca aatattgtga tggactcgtt cctgactatg cctcacttgt cactccattt
    42661 gatagtgaac tgtctacgac ggctgctaac gttgtcggac gttaccatga tgcaatggaa
    42721 aaaatggaat tcaatacagc attggctgaa atctgggtgc tgatttctcg tgcaaacaaa
    42781 tacattgatg aaacagaacc atgggtatta gcaaaagacg aagaaaagaa agctgaattg
    42841 aatagtgtca tgatccattt agctgaatct ttgcgtatcg cagcgatatt acttcagcca
    42901 atcatgacag aaacgccaga gaagatcttc aatcaactag gattggactc tgaaacaatg
    42961 aatcttgaag gattacactt tggcgaattt ccttcaggaa caaaagtagt tgcaaaaggt
    43021 acaccaatct tcccacgttt agatatggaa gaagaagttg cttttattca agaaaaaatg
    43081 tctgaaggta ctcaaacaaa cgaagataca gtcaaatggg atccagaaga aacagaactt
    43141 gtttcaacga aagaaaaaca aatcaaattt gatgtatttg aaaaagtaga actaaaagta
    43201 gcagaagtca tcaactgtca aaaagtagaa ggggcagata agttgctgca attccgacta
    43261 gatgctggag acagccaaga ccgtcaaatc ttgtcaggaa tcgctgaatt ttatcctgat
    43321 ccaagcgaat tgatcgggaa aaaagtcgtc attgtagcaa atctgaaacc acgaaagatg
    43381 cgtggacaaa tcagtcaagg aatgatcctt tctgcagaag caccagatgg ctctttacaa
    43441 gtaatcgaag caccaaaatc catgccaaat ggctcagaaa tcgcatagaa attcaaaggg
    43501 ggtatgacac tagttgtgtc ataccccctt tttccgaaat ttgagaagca attttcgtaa
    43561 attccttctt attacttgaa gccaatcata taatacagaa acagagaact atccaaaata
    43621 aatcctagaa aaagaagtac gagcttcgct gatttttgtt aatttagaat aatactaata
    43681 ggaatcgtaa aaacagaaaa aaagcataat gataaagggt cgggcagatt ttaattgatt
    43741 catctggtac tcttttttat tgtccttaca ttcataaagt ttgaatgcaa tgactttatt
    43801 acatctatat ttatatctaa cagtagcgtt gatgtgttaa ttataagttc tatcacttta
    43861 tgttcaatta gtttgtgctc ttatatgtgt gattgaaaat atagataaaa aaacaatcat
    43921 cggctttgac ttcgatgatt gttttcttta ttttgtaaaa atcctatcac ttgattttat
    43981 ggtaaccttt tatttttgtc ttcaaacggc ttggtaagag agcagtaagc agtgcaaatg
    44041 ggatcgaaaa gacataccag aaaatcgtac gtccgatacc ataatgttga tagagctttg
    44101 tcaacatcac gtgtaacaag atcaacccta aaagcaagga gccagctata aaccaatgat
    44161 tatcccaatg catgacttca ctaagtgcca tcactccaaa aggatagaaa taaaaataga
    44221 tcccgactaa ggtcatccgc cagttctttg taaatgttcc gatattcaat aaaaagaaaa
    44281 tcgctgaaag caaaataccg ataggcggaa aaagcccaac caaaaaggaa tacaacatcc
    44341 cccacaagat catcacagga cctttgatca atgcaacgat tgcgatgaac aaagtcagca
    44401 atattagttt ttgtgataac gttgcaacag tcattaatcc aaataaaatt aatgtgaacc
    44461 aatgccaatg ggactgctgt tgttctttac gggaaaaatc gacccggttg gataaataat
    44521 ctgctaattt cggataagaa cgcttaaaat ccataaactg ttcctccttc gtggaaaagg
    44581 taggtttagt atacgaaaaa taaaaaagaa atacatccgt cttaagaggg agtttttcac
    44641 tgaaagtgga gaaaaaagaa tggtaaatta aaatattctc agttatactg aaaattatac
    44701 caaatttcaa agaagaaaga ggatgggaat gaaaggcaaa ctaaaacgag aaatcaatct
    44761 gtttggcgca ttagctaccg ttatgggaac cgtgatcggt gcaggcgtct tcttcaaaac
    44821 tgctgctgtt actgctagta ctcagtctac aagtttgaca ttgctagctt ggcttttggg
    44881 tggtttctta acgatctgtg ctggattgac agtggctgaa ttagctacag caatcccgga
    44941 aactggtgga gctgtaaaat atattgaagc tgcgtatgga aaattgccca gctttttatt
    45001 aggatgggcg caaagcttga tttactttcc tgctaatatt gctgcattat cgattatctt
    45061 tgcgacacaa ttgacgaact tattacaatt atctaccgat tatcttttgt tgattgcagt
    45121 gatcaccgct gtttctgtga cagggttgaa tttgttaggg acaaaagtcg gtgcttctgt
    45181 acaatcagtg acgttgattg ttaaattaat accaattgct gtgattgtca tatggggatt
    45241 attgacccca ggacaaggaa ctgtccagtt atttccaatc gaagctggaa aagatgttac
    45301 ttttgtcgaa ggattgagca gtgcgttgtt agcaacgttg tttgcttatg acggctggtt
    45361 aggtgtcggt gcaatggcag gggaaatgaa acggccggaa aaagatttgc ctaaagcaat
    45421 tattcttggt ttgagttttg taacagtcgt ttatctattg atcaattttg tttttttgaa
    45481 aactttgccg attgatcatc ttgccggtaa tttgaatgca gcttctgaag catcagacgt
    45541 catttttgga ggaatcggtg gaaagctggt cactattggg atcttgatct cggtatacgg
    45601 tgcattgaac ggttatacac taactgggat ccgcgtgcct tatgcgatgg ctttagaaga
    45661 cgagctacct ttcagtaaac agctgacaaa gctttcaaag aagtttacgg ttccttatgt
    45721 tcctgcggtt ttccagttag cagtagcttg tattatgatg agccttggtt ctttcgactt
    45781 tttaacagac atgttgattt ttgtgatgtg gctattcagt ttactgattt ttatcggtgt
    45841 ctttatttta agaaaaaaag cgccggaatt gccacgtcca tataaagtac cactttatcc
    45901 aatcgttccg attattgcga ttctcggtgc tattttcatt ttaggtatga cgatgatgac
    45961 gcaaacgaaa ttagcattga tcggtatagg tgttaccttg ataggtatcc cagtctatta
    46021 tcaaaaaaag aaaaaacgct cagaagagta aaatatttca acaacagaca gaaaaagtac
    46081 gaactaggtc ctctagatct tcgtgctttt tctatttcaa taaaacaagt tcttctattt
    46141 tgatttttgc tacttctgca agtagtgctt atgtgctaaa gtaagaatga aaaggagaga
    46201 taaacatgat atttgattct catacccatt taaatgctga acagttcaat gaagatattc
    46261 cagaaacgat tcagcgagca caagaaatgg gggtaacgaa aatggcggtc gtgggcttcg
    46321 atacgccaac gattgaaaag tctttgcaat taagccatga ctatccaaat atatacagta
    46381 ttatcggctg gcatccgaca gaggctggca gttatacgaa agaaatcgaa aataaattac
    46441 aagaacaatt gactttacca aaggttgtag cattagggga aattggcttg gattatcatt
    46501 ggatggaaga cccgaaagaa gtccaagata aagtatttcg cagacagatt gctatcgcaa
    46561 aagaaatgaa cctaccaatc agtattcata ctagagaagc acttgaagac acgtatcaaa
    46621 tcctaaaaga agaagatgtt cgagatatcg gtggaatcat gcatagtttc agtggtgatt
    46681 atgaatgggc aaaacgattt cttgacttag ggatgcatat ttcatttagc ggtgtcgtca
    46741 ctttcaaaaa agcattagac gtccaagagg ctgcagcaaa tgtaccaatc gaacgattac
    46801 ttgtggaaac agatgcccct tatctggcac cagttccttt tagaggaaag cgaaatgaac
    46861 caggctatac tcgttataca gtagaaaaga ttgctgaact tcggaatctt ccgacagaag
    46921 aagtggctgc ccaaacatgg acaaatgcgc accgattatt tggtctaagc gaacatggat
    46981 aagatgaaga tccaagagat tatagtcgtt gaaggaaaag acgatacaag aaggctgcgg
    47041 gaagtagttg atgcagatac gatagaaaca atagggtctg caatcaatga agagatcctg
    47101 atgcaaattg aacatgccca agagactcgt ggagtgatcg tttttaccga tcctgatttt
    47161 tcaggagaaa aaataagaaa aatcattatg gaagctgttc ctcaggcaaa acatgctttt
    47221 ttgccgcgca cacaagctaa accaaagaaa aagggaagcc ttggtgtcga gcatgcaagt
    47281 gatgctgcta ttttagaagc attgaaaaag gtcgtgacgc cagacatttc ccaaacggct
    47341 gtttctgaaa tcactagaca agacctttta gactatggtt taatagctgg ggcacaagca
    47401 aaagaaaaac gagaaaaact aggtgacgag ttgcgcatcg gttacacgaa cggcaaacaa
    47461 ttggaaaaac gtttgaagat gtttcgtatt acgccgaaag aactcgccca agcaatgaaa
    47521 atagtggagg aacaacatga gtgaatatcg tgaaattgcg acaccctcta gaacaaaaga
    47581 gattttattg aaacatggtt tttcatttaa aaaaagttta ggacaaaatt ttctgactga
    47641 accaaatatt ttaaggaaaa tcgtagaaac tgcgcaaata gatgaacata cgaacgtgat
    47701 cgaagttgga ccaggaatcg gtgcattgac ggaacaatta gccaagcatg caaaacaagt
    47761 cgtagcattt gagatcgatg atcgtttgat ccctgtattg gctgatacga tgcaacccta
    47821 tgacaatgtg actattgtac atcaagatat tttaaagacc gatttgtcaa cagctgttag
    47881 agaaacattt catgaggagc ttccgttaaa agtcgtagcg aatttacctt actatattac
    47941 gacaccgatc atgatgcatt ttcttgaatc agatttggtt gtggatgaac tagtcgtcat
    48001 gatgcaaaaa gaagtagctg atcgtatctc tgctgaacca ggaacgaaag cttatggttc
    48061 attatcgatt gctgttcaat attatatgga agccagttta gcattcatcg taccaaaaac
    48121 agtatttgtc cctcagccaa atgtagattc agcgattttg aaactgacaa gaagagatat
    48181 accggcagtc gaagtgacag acgaaaaagc atttttccga ttgacaaaag cggcatttca
    48241 gcaaagaaga aaaacgcttt ggaataactt gcagcattcg tatggcaaag atgaccagac
    48301 aaaagcatgg ttagcaaaaa gcttggaaac agctggaatc gatccaaaac gtcgtgggga
    48361 gactttgtca ttacaagaat tcgccgcatt aagcaatgcg atgtcagaaa atatgcagta
    48421 aaaaaagagg ttgtgacaga agttgtgaaa aagctgtcct gcatcaagta ataagaacag
    48481 ccaaacaaaa atagttcctc atgtttttcg tttgtttggg cttattaccg cagatgcaag
    48541 cttttgaaca ccgtttaaga aagaggttgt gggcctgccg tttaactcta agtcacaagg
    48601 aacaatttca aaaaacagct tctcatgttt ttgagttagt tggtcttatt acttgatgca
    48661 agcttttgac cactattatg ccgaacaagg agatgtgaca caaattttgt cacatctcct
    48721 atttttgttt cttgatcaaa aaattcttat acttgatact cacactcatt ttgtatggat
    48781 ttagaaaaga atatgtgtct tgacagttat tagtaagtga gttatactaa gtcgacattt
    48841 atgtgtcaag acatattagg agagagaaaa aatgagaaaa aattcagttc gaaaactaac
    48901 gatttctgct ttattgattg ggatgggggt cattatccca atggtcatgc ctaaaatcat
    48961 gattccacca gcttccttta ctttggcgtc tcatgtgcca ttatttattg cgatgttttt
    49021 tacaccagga gttgcagtgg ctgttgcgct aggtacgaca tttggtttct ttttaacaac
    49081 gccggttatc atcgcattgc gagcattgtc acatcttgtg tttgcgttga ttggggcttg
    49141 gtacttgcaa aagcatccga gtatcgtttt aaaaaatgga cagtttactt ttgctaattg
    49201 gcgtttccaa gggttcaatt ttgtgatcgg tgtgattcat tctttagcag aaatgctagt
    49261 agtcagcatc ttttacttta ttggtaatat gcctgaaaca tattattctc aaggatattt
    49321 ttatacagta ttcatcttga tggggattgg tgggcttatc cacagtttag ttgattataa
    49381 tattgcttat tttatagcag gaacactcag caaatatttt gatatccccg tatttacggc
    49441 agcaaaaaaa gaaaatcgga aagagtcgat tcaagggtac gcgaagaaaa cgacatatta
    49501 gacatgatct ctcaaaaaaa aaactctcat ctagtaatgg ataataaatc ctctaagatg
    49561 agagtttttt gtcctaaaaa gagctgcacc aacatcttct ggcacagctc taacaggggg
    49621 caatttatgg aagtttgatg acttgttctg tttctttatc aaagaagtgg cctttgctga
    49681 tgttgaaggc aaggtcgact atttcgcctg gtttatggaa atctcttgca tctacttttg
    49741 agatgaactc agtagaacca gtttttgtgt aaagcatcgt ttcagctcca agtaattcgg
    49801 aaacgacaac ttctgatttc actacggctt caggtgaagc ttcaagggct acttgttcac
    49861 tgtggatgtc ttctggacga ataccgaaga taacttcttt tccttcataa cctttttcaa
    49921 ctaatacttt gttttttcct tcaggaatac gaagcttaag cccatgtcca tctgtgataa
    49981 caccattttt caatgtcaca ttaaagaagt tcatggcagg agatccaata aagccggcaa
    50041 cgaacatatt gacgggtgta tcataaactt ctttcggtgt accgatttgt tggataaatc
    50101 cgtctttcat gataacgatt cggtcagcca tagtcattgc ttctgtctga tcgtgagtaa
    50161 catagatggt cgttgtttca agacgctggt gaagtttggc aatctcagca cgcatggcta
    50221 cacgtaattt agcatctaaa tttgataatg gctcatccat taagaagact tttgcatccc
    50281 gaacgattgc ccgtcccaat gccacacgtt ggcgttgtcc accagataaa gcagctggtt
    50341 ttcgtttcaa gtattctgtc agacctaaga tctctgctgc attgtccaca cgttttttga
    50401 tgtctgcttt atcatattta cgtaatttca agccaaaagc catattatca aaaacagtca
    50461 tatgaggata caatgcgtag ttttggaaaa ccatggcaat atcacggtct ttaggtgcca
    50521 cgtcattcat gacttttccg ccgatattta gttctccttc agagatatct tccagtcccg
    50581 cgatcattcg caaagtagtt gactttccac aaccggaagg accaacaaaa acgataaatt
    50641 cacggtcttt gattgataga ttaaaatcag ttacagaata attttctgca ttgtcatatt
    50701 ttttatatac gtttttcaga gccatttcta ccataatacg ttccacactt tcttttttag
    50761 ttttattaac tatttaaagt ataaatgaaa gcgttaacta acttcaatgt catgttgaac
    50821 aagaattttt tctttttttt gtcaatgtgc tagttttaag ctttaataaa tatccataag
    50881 aaataaaaac tgatacactg gagtaaataa gtatgttaac aatatcaaaa ggagtgtctc
    50941 ttatgaaaat cgctttgatc gctcatgacc gaaaaaaacc tatgatggtg aaattagcaa
    51001 cagcgtataa aacaatattg gaaaaacatg aactttttgc taccgggacg actgggcaga
    51061 ggatcacgga agcaaccggc ttgccgatcc atcggtttaa atccggaccg ttaggcgggg
    51121 atcagcaaat tggagccatg atttcggagg atcagttaga tttggtgatt tttcttcgag
    51181 acccgctggc tgcacagccc catgaaccag atgtaacagc acttatccgt ttatctgatg
    51241 tctatgagat tccgttagct acgaatatcg gaacagctga ggtgctacta agaggactgg
    51301 aagccggctt cctagatttt cgaagaatcg tccatgaaat agacaagcat ccactttcat
    51361 tttgatggat aagcgtatgg aaaaataacg tttaatgttc gcctatatgt agctataaaa
    51421 gctaaacaaa ctgataatat gcgatataat acgaacgtat tggataatat aaacaataat
    51481 attagttttt cgtatttgca gtaaatgtga aaatatgcta tagtttctgt gggaaaagat
    51541 cccaaaaata atacagagta gaaaataaag cgttaagtgc taagaggatg ggatgttgcc
    51601 tcttggacga aggacgtaat gttcgcggtt ttattttcgc attcgctgca tgatacgatg
    51661 tagcagctct taaaggagat gctaaaaatg aagaaacacc ggttagacgc acgtatgatt
    51721 gctattatgg gcttattgat tgcattgatg gtcactttgt cccgactggt agcaatcgag
    51781 accccattta ttaaaatcag tgtcacattt attccacaag tgatcatggg cattcttttt
    51841 ggtccttttt ggtcagggat aggcgcagtt ttagctgatt tagtaggaat ggccctcttc
    51901 tcgaaatctg cattctttat tggatttaca ttgaatgcat ttattgaagg agcaatctac
    51961 ggattctttt tctatcgaaa agagatcact tggaaaaatg ccattctggc tacgcttagt
    52021 gtcacgctga tcatcaactt atttttgaca ccattatggc ttgcgttgat gtaccatgtg
    52081 ccattgttca gctgggtcgt ttgggcgccc cgcctgttaa aaacagtaat atggttaccg
    52141 attcaatcaa ttgccattta ttacgtagga cgtagtattc cttacaaaaa aattttaaga
    52201 agtttagcga tccacgctaa ataaaaaaca agcagtcttc ccatcccaga agactgcttg
    52261 tttttattgt gctgtgaatt gtgcttgata gagccgtcgg taataaccat ctttttgaag
    52321 cagctcatca tgggtgccca tttcgacaat agctccctga tccatcacta atatctggtc
    52381 cgcatttttg attgtggaca ggcgatgggc aatcacaaaa ctggtttttc cttccatcat
    52441 tgctaagaag gcttgttgga tttttttctc tgtcaatgta tcgactgagc tggtagcttc
    52501 atctaagatc aacatagggg gattactgat catcgttcga gcaatcgtca acagttggcg
    52561 ttgtccatct gatatcttta acccttgacc gccaatctta gtatctaatt tttccggcaa
    52621 acgttctaca aattcataca tataagaggc ttttagggca tcattgattt ctgcgtcact
    52681 tgcttccgga ttcccaaaac gaagattttc tcgcaatgta ctgtcaaata gccaagtatc
    52741 ttgtaacacc attccaaaac ttttacgtaa tgtatcacgt tggatagagc ggatgtcatg
    52801 gtcatcgact gtaattgttc cttttgttgt gtcataaaaa cgcatcagca aattaacaag
    52861 tgtggatttt ccggcccctg tttttcctac tatagcaatg gtttgacctg gataagcagt
    52921 aaaattgaaa tcttcgatca aacgctgctt ggggtcataa gaaaaagaaa catgatcaaa
    52981 agagactttt cctttgatat ttttgggttc caaggcatag gcatctggca aatcaggctt
    53041 ttcttctggc tgatcgatca aatcaaatgc tcgttctaga ccagaaaaag cggtttgcag
    53101 ttgtgtcgtg attccagaaa gttcgataaa tggtttagaa aactgacttg agtagatcgt
    53161 aaagctggaa atcacaccaa cagtgattga cgaaccactc ttcaatgcca ataggccgcc
    53221 aactaaacca atcgataaat aagcaaggtg atctacaaaa cgagaagacg ggtttgtcaa
    53281 ggaagaagaa aattgtgccc gttgtccttt ttcatataga tcagcattta gcagttcaaa
    53341 ttgctgttga ctagcttctt cttgctgaaa agctttcacg attttctggt taccgattcg
    53401 ttcggtcaca aagcccgaga tatccccaat aatcctttgc tgtctatcga aatttgtttg
    53461 tgaagcacga gcaacgatcc aactcacaag gaaaataatt ggtgtagaac aaagaacgac
    53521 caatgtcaga agtggactta gacgcatcat aaaaataaac gaaagaatga tgattgccac
    53581 tccagaaaat aattgattga aggccgcaga aattgcaatg gaaatattgt ccatatcatt
    53641 tgtaaatcga ctgacgatat ttccgtggga gttttgatca taataacgaa gtggcaatcg
    53701 attcagatga gcaaatgcat cttttcttaa ttttgcaacg gataagtaag ctaaccgatt
    53761 gcttaacact tggatgagcc attgactgac tacgttgatt aaaacgatac caccgaatag
    53821 aataagtaaa tggaacagtc gattgaagcg gacctgtcct tctccaatca tttgatcgat
    53881 actttgacca atttgtaacg tcatcacaac tgttgcaatc ccattgatga ttcctagtat
    53941 cacagctagc caaatgtctt ttgcataggc agtaaggtaa ggaatgaatc ggcggagcgt
    54001 ctgcaaggat aattttttta ctttcataac tattcttcct cctgtgatgc gacgatttcc
    54061 tgatattctg ctgattgagc aagtaattct tcatgggtac cctgagcagc aatcttacct
    54121 tgatccatca ctaagatatg atgtgcttct tgaatagagc ggacacgttg ggagataata
    54181 atcactgtac tgccaagata agtctgtagc gccttacgca aatccaagtc tgtttgataa
    54241 tccaacgcac ttaaagagtc atctaaaatc agtaatgctg gcttggcaat caaagctctt
    54301 gcaatcgtca gtcgctgttt ttgtccgcca gagaaatttt tcccattttc catgactttt
    54361 gtatctaaac catttggaag ctgacggaca aattcttctg cctgagcgat tttcagagct
    54421 tcccaacatt ctttttctgt ggcgtctttc ttaccccatt gaaggttttc acgaatagtc
    54481 ccggtaaata gtacagaagt ttggggaaca agagcaattt gctgacggag atgatccagc
    54541 tgccaagaac gaacatccat tccgtccatt ataactgtac cggaactgac atcatagaaa
    54601 cgcggaatca attgtgtcaa agtcgttttc ccgcttccgg ttggaccaat gattccaagg
    54661 actgtatttc gcttcagctg aaatgtaata ttttggagag aaagaccaga atcaggagta
    54721 taacggaagt caacatggtc aaaagcgata attgcttcag aagaaaaatc gggagtagta
    54781 ctgacctcag cttcaagaat cgaattttct gtgtctagca cctctttcac ccgatttcct
    54841 gaagcttcgg cacgtgtgaa gatcacgacg aggtttgaaa caacgatcag tgccaaaagc
    54901 atttgattca tataattgat caaagcaaga acttgtcctt gttgcaagct accaatattt
    54961 actttgatcc cgccaactgt cagcaaacag atgatcccga cattcatgat caaggttgta
    55021 gcaggtgata atagggcaga gatattggaa acacgtaaat aattgttcgc tagatcattt
    55081 gtgcttttat cgaacttctc tgtttctttt tttgtctgcg caaatgcgcg gatgacacga
    55141 acaccgctaa gattctgact aacgtgttca ttgagctgat ctagtttttc ttgcactttt
    55201 tggtagagag gaacggtttt tttgatgata aaaaataaaa tgattgagaa aataggcaat
    55261 aatgctaaga aaaacagacc tacttcccag tcgatcacaa aagccatgac cactgacccg
    55321 atacttaaaa acggtgctct gatcaataaa cgaatgacca ttgctaaagc tagctgaagc
    55381 tgattgatgt cgtttgtcat tcgggtgatc aaggtatctg ttccaaaatg attcaactcg
    55441 ttgtgagaga aagtattgat ttttttgatt agctgattac gtaactctgt accaaatcct
    55501 tgtgaagcta ctgaagcata gtattggcaa atgatagcac aaatcagacc aatcacagac
    55561 atagcgacca tccataagcc catttcaatg atttttcctc ggtcattcat ttttagtcca
    55621 ttatcgatca aggaagccat cattaaaggc aggacaagtt cgaagacagc ttcaagaaat
    55681 ttgaagaacg ggcccaaaat gatttgctta cgatagtctt ttgcataacg taataactga
    55741 atcatatgat tcctcctatt atttatttgt ccacaattga aaaaacaagt actaccacat
    55801 tgtagcttag gaaatttaga atgaaaagag aacaagcctt ttcataaatg aaagttttat
    55861 tatgaagaag ctttagaaat tgaatagact atttttttta aaaaaaagaa aatgagaaaa
    55921 catgccagtc tcttcattca taggaacgtc tattttactt aatttttcta taaatgaatt
    55981 ctgcataaaa aatatatcaa gtaaatgttt atagatgaaa ctctatttac ttctttttta
    56041 atttgttctt gcaatctttt ttgctacgta atttttgtaa aaaagtgggt tgagagaaat
    56101 ctaattgatt ttcaaagaag gagtatgaaa atgagaaaaa tatttattcg tttattgtgg
    56161 gtactatctt agaggaataa ataatagtgg agaaaactat ggtttggcgc agattctatc
    56221 aggtttgatg gaacgaagac aacctcccga catcaagtca aaagccactt gagattttga
    56281 tctgaaaata aaaaaagaaa acaaggtagg aacatcaatg tttctacctt gttttcgtaa
    56341 tcaatgggaa aaaactaaga gtggtgtacg taatcaataa aaaggatggt gacaacagta
    56401 cctctttact ctctgaaagc atcataactc gtttttcctc attatgccaa taaattgttg
    56461 ttataccaca tataaggatt tgtaatagct aaaaacagac aggaaagttg aaatctgtga
    56521 atcttatttt gtatggaagg atttatagaa cgcaaaaatc aagataaaga tgaataaaaa
    56581 tcctgtttcg gctatatatt gcgtatctac gccaataaaa cgagtttgtt ctgtcatagc
    56641 catataaagc aaaggcaaaa atacaactac agcgagataa gatccgatga tttctcgaaa
    56701 agttttccag gaagtatgtt tcctgttttt atatttatcc gatttcattg aatagtcata
    56761 gcctccttat tctttcatat gttgaaattc cagtataaaa actggaagga actgtacgtt
    56821 ttttagaata aaaattataa gggataagta ggctgctgtc tataataaga tatatttttc
    56881 aattctttat taaagatttt attgacaaaa tgaatccgtt ttctatgatg gaggaggggt
    56941 gaataagttg ttgaagaagg aaattttatg ttacttagag aaccagacag cctttttcga
    57001 tttagaacat atgaacgagg tctttacagc acaaaggtta gctgatcatt ttggggtaaa
    57061 aagaaacaca gtcagtcatt atttgaacca gttaaatgat gagcaactac tagtcaaaat
    57121 caattctcga ccagtgattt atttccacaa agaagctttt gaaaaacaat tttttaagtt
    57181 acgcacgaat ttttattttt ctatcgatga tctcaaagag gaacagcctt ttttcgcgca
    57241 accaaaagac ttattctctt ttatgatcgg atacgacgcc agtttgaaag aaagtatcga
    57301 acaaatcaaa acagctcttt actatccaga tggcggatta ccacttttga ttacaggcga
    57361 aagtggcaca ggtaaaagtt atttagttaa tttggtctat cagtattgtc tgcttcatga
    57421 tctgctagaa gattctgcac cattcatcac ttttaattgt gcacaatatg cagataatcc
    57481 tgaacttttg actagcaatt tgtttggaca tgttaaggga gcgtacactg gtgcagaaga
    57541 aaataaaaaa ggggcttttg aagcagcaga tggtgggatc ttgtttttag acgaggtaca
    57601 tcgcttaaca ccagaaggtc aggaaaaact gttcacctat cttgatcaag gtgtgattta
    57661 tcgtatggga gaacctaatt tgtcacgccg gatcaaaaca cgtctctttt ttgctacgac
    57721 tgaagagatt actagtcatt tcttaacaac tttcattcga agaataccta tccgaatcga
    57781 actacctgca cttaatcagc gtagtcgtaa tgaacggcta gaactgattt actctttttt
    57841 tctcgaagaa caaagaaaaa tggggagccc tttgtcagtc agtggaccag ctttgtcact
    57901 tttaacaagt cagaaattat ccggaaacat aggagagctg aaaaatatcg tcaaagtttc
    57961 agcagcaaaa gcatatgctg aacagcgtga acagcctgaa atccatgtca cgatccatca
    58021 tttgcaaaaa gaactacttg cgcagcctat tactaaaaat acagcacagc aaggaatcta
    58081 tattacgcaa gaccagacct tagagcaatt aatggagaag caacagcccg aacagcagcg
    58141 aatcgttaaa agttttgagc aaatcctaat tgatttcaag aaaaataact gtctgctata
    58201 ttcttgcgaa ggaaaattaa agcaagaagt gattcaatta tttgattttt tgctgtttga
    58261 gaccagtaga caagaaaaac acgagctgct ggtttattgg acacaatcta tccgagagac
    58321 ctttcgacaa atggaaactg cctatcaaat caaattcgat ggaaacagtg tctatgcctt
    58381 gagttactat ctctatcagc gaagcactat caaatggtta ccggaagaac atgatattat
    58441 ccaactaatc aaagaattag aacaacaagt ttctcagtct tatccatcta gttatcacta
    58501 tgtccaacga attctggaat taagtaagat caaattagat attgaagaca caagtatgga
    58561 tcggatttta ctgacgatct atctaaaaaa agcgaaatgg tcaaaagaaa aacgactgcc
    58621 aaaagcgatg attgctgctc acggttatgc aactgctagc agtatggcaa atgtagtaaa
    58681 tcgtttatta caagaggatc tatttgaatc atttgatatg ccactagatg tcacaccaca
    58741 gcagattgct tcagaaatcc ttgattattg cgaaaacagc gatgtttcaa atggattgat
    58801 catattagta gacatgggat ctctgaaaga aatccatcag ttttttaaaa aacagttatc
    58861 cgtaccgctt ttgattttga ataatgtgac gacaccttta gcaatcacag taggggaatg
    58921 cctgcaaaaa aatgtatcat tagaagagat agcagaagag actgttcgac agatccagcc
    58981 agaatggcga ctgctctatc cagaggaaaa caaacccaaa gcactcatta ctacttgctt
    59041 cactggaatc ggtacggcgg tccacttaag tgaactgcta gaaaaaagct tacctacggc
    59101 ttgtcagttg aaaatcatcc catatgaata tcagcaatta aaagataaga aaaacagtga
    59161 cccattattt tccatatacg aagtcgtagg aatgattggc accacagatc ctgatatcac
    59221 caatatcgac tatctttcat tagaagacct catctcgggg gaaaagatgt ctgtactagc
    59281 tgaatggttg gacactacta tgaatgcttc agagaaggaa atattcaatc agcgcatcat
    59341 tcgtaatttt tcattggaaa aagtactgga ttccgtgact attctagata cagagaaggt
    59401 gatgggagaa atcgatcatt ttatgagaga attagaggtg cagttgaatc gaagcatcag
    59461 caatcccaaa aaattagcgt tgtatgtcca tgtgagctgt ctcattgaac gattgatccg
    59521 acaaatgcca atcgaaacct atcaaggatt agagaaatgg aagcagtgtc aaaaagaagg
    59581 gttatctgct attaaatctg cgtttagtgt cattgaagag cattatagtg tcatgatccc
    59641 caattctgag attgcctata tctatgatat tttgagtgaa gatacagagt ttctctcgat
    59701 agaagaagaa ttttgaacat aagcaagttg ttgccactaa ttttggcatg caacttgctt
    59761 ttttagtatg tgtaagtgaa aagaggagat gaaaaagtgg atagagaaat tatcttagct
    59821 tcccatggaa aatttgcttc agggatatta gattcattag agctgatcta tgggaaaaat
    59881 cattctatta ctgtattcga ttgctatact gatgagaatt ttgatttagc ggaaacagta
    59941 aggcagcttt ttatgaggta caaagataaa gaaatcattg ttctgacgga tctttttggc
    60001 ggaagtgtca acaacgaatt cttacaatat atcaatcggg atcatgtcta tctcgttgcc
    60061 ggattgaatt tgccactatt gattgagcta gtatctcggt tggacgctga agtagagaca
    60121 actgttttga tccagcaggt gctaactgat tcaaaaaaaa tgatccagtt ttgtaacgag
    60181 cggctcaatc agaaaataga agaagacgaa ttttaggagg aagaaaaatg attgtattga
    60241 caagagtcga ccatcggtta ttacacggac aagtagcttt ttcatggaca caaacaatag
    60301 gcgcagactg tattttgatt gctaatgatg atgtacctac gaatgagata cgaaagacaa
    60361 cgatcaaatt agccaagcca caaggagtca aactagtgat caaatcaatt gatgactcga
    60421 ttgccgcgtt gaaaagcggg gtgacagata aatataagtt attcatcgta gtggaatcga
    60481 tcgaggatgc atataagctg gcagaagcgt atccagaaat caaaaccatc aacttaggag
    60541 ggatcaaggc aaaacctggt actcgcagca tcggaaaagc ggtaaatatt ttaccagaag
    60601 aggaggaacg cttgaaacga ttaattgaca aacaaataga agtagaaatc cgtcaagtac
    60661 cagcagataa aaaagtggat gtaagagaag ttttgtaaga aaggaagaac ctcaatgatt
    60721 gtacaagcag tcttattagg aattgttgca tttgtcgcac aatcagaata tgcactaggg
    60781 acatcgttgc tttctcgtcc gattgtgacg gggctgttta caggaatcgt gttaggtgat
    60841 gtaaaaactg ggatcattat gggcgcaact ttagagttag catttatcgg atcgttctca
    60901 gtaggtgctt cgattccacc tgatgttgtg accggtggga ttttagggac ggcttttgct
    60961 attacagctg gagccggtac agaaaccgcg cttttactag gtttgccgat tgctacgttg
    61021 acattgatat tgaaaaatat ttacttaggg cttttgattc caattatgaa ccataaagca
    61081 gacaattatg cagaagaagg aaattataaa ggagtcgagc atatgcactt gcttgccggt
    61141 atcggtcttt ccttgatgct tggtgttgtg gtaatggttt cttatatggt gggaagcaat
    61201 acgatcggaa atctattaaa tatgattcct gacttcgttc aaaaggggtt gtcagtagct
    61261 acagggttga ttccagctct tggttttgcg atgcttgctc gtttgctgat caacaaacaa
    61321 gttgcaccat attttttctt aggttttgct atagcttctt acttagagat tcctgtgacc
    61381 ggagtagcta tttttggtgc gattttagca gttgtggtag tcaatattat gaatgtccgt
    61441 caactaccac ttcaaacaac tgcaggggag gtagaagaag atgaagaatt ctgagatcaa
    61501 aaacagcaaa ataacgaaaa aagagctaaa tcacgtattt tggcgttctt ttcaaatgga
    61561 gttttcttgg aattatgaac gtcagatgaa tatggcttat gtttatgcaa tgattccgat
    61621 tttgaaaaag ttatatcagt cgaaagaaga aatggcagca gctttgaaac ggcatctaga
    61681 gttttttaac acgaccccac atatcgttac actgatttta ggaatcacgg ctgcaatgga
    61741 ggaagaaaat aaggatgatc ctgaatttga tgtgactgcg atcgatagta tcaaaacatc
    61801 tttgatggga cctcttgcag ggttaggaga ttctttcttt tggggaactt tgcgattgat
    61861 tgccacaggt gtgggtacct ctttagccat gcaaggaaat attttaggcc ctatcttgtt
    61921 cattttgatt ttcaatattc cgcacattct gtttcgctat ctagcaacag gttggggata
    61981 tcgcttagga acgggttttt tgaaaaagat ccaggcaaac ggtatgatgg aaagtttgac
    62041 attaggcgcg tctattattg gactgatggt cgttggagca atgactgcca cgatgatcac
    62101 catcaatatt cctttaaaaa tcggttcagg agaaaatgct gtgactgttc aaagtatttt
    62161 tgatgatatc gttccaaata tcttatgtct tggagcattt ggcatagtgt tttatctatt
    62221 gaagaaagaa gtgaaaccat taacgatctt gatcggacta gctttctttg gaatttttgg
    62281 ttcgtggata gggatttttt aaaaaaggag cagagaaaat gtttacgatg caagattata
    62341 tctatgaaga aaaggaagta ctaagtacga tcttgaaaaa gaatgatttt tcgacaagag
    62401 aacatatgaa aaaaacagtg aatttactga tcttagcaac gggttcatct tataacgctt
    62461 gtttagcagc gaagccagca ttggaatctt atggtgatct tactgtcgat attcaagaac
    62521 ctttttattt tttcaattat ggaaaacttt ctccttcaat cgatactgtg attgctgtgt
    62581 cacaaagcgg gaaaagtgct tctactgttg aagcagtaaa aatgatacaa aaacaagggt
    62641 tacctgttgt tgctatcaca aatgacgtgc aaagtccact tgctttagaa gctgcacaaa
    62701 ttattgattt aggtgccggg gtagaatcag taggcttcgt tacaaaaggc tattctgcga
    62761 ctgttttaca gttactactc ttagggatag gaattggaat aagtaaaaat aaaatcagca
    62821 aaaaaataga acaagactac atgcaacagt tgcgcaaaat aatcaaccat ttaccagcga
    62881 ttattcaaaa aacggaagaa ttttttgatg gatatcaaag tttatttcgt ttagcacagc
    62941 gtttcgtcac cattggatat ggtccaaact ggggaacagc taaagaagca gagacgaaat
    63001 tgactgaaac aatccgcgtt ccgtcacaag gatttgagtt agaagcttat atgcacggcc
    63061 catacctgga ggcagatgct tcgcatttgc tattctttat tgaaggggaa agtgtaaata
    63121 aggaacgttc gcaaaagttg caaagatata tgagtcggta cgttggagag actctcacca
    63181 ttaccacaaa aaaagcaaga aacgagaaaa cacttggatt agcaatagaa tgtgatgaat
    63241 atctgtctgt attagcgctt gtcgttccgt ttcaactatt cgcttataaa accgcagtag
    63301 ctaaaggtat tgacttgaac aaaaagattt ttgaagactt tgatacagtc ttgaaaagta
    63361 aattataaga ggtggaaatc atgctgaaat tcaatgaaga agaacaaatc aaagcaataa
    63421 aaggcgcact agctttacgt ccgcaagtag aagaaatcat cgataaactt tatgcggaaa
    63481 aatttgacgc tgtctattat ctaggaatcg gtggaacgta tgcttcctcg atgcaagctg
    63541 tcacttatat gaatgggaaa agcaacttgc ctgtctttgt acagcatgct gcagaatatt
    63601 acactactgg aaacaaaaga ttaacaaaag attctatcgt tattttgtcc tctgttaccg
    63661 gtacaactca agaagtagtg aaagcagtag aacaaatcaa gaaagtagga gcgacactga
    63721 ttggatttat cgataaagcg aacagtaagt tgtctcagct atgcgatttt gtggtcactt
    63781 atccagctcc tggaacagaa caaatcaaat tttttatggc agcagatcga ttgatgtatt
    63841 tgaatggaga attcgaagct tattcagaat actatgaaca gctcgaacgt tatttaccaa
    63901 cagggttagt ggaagcagag aaaaaagcag atgcatttgg cttatcattt gcagaaaaac
    63961 atcgacgtga tagtatgcat tattttattg gagcagggaa tcaatgggga gctgtttatt
    64021 catatgccat gtgttactgg gaagaacaaa gctggcttcc atcgaaatct atccatgctg
    64081 ccgagtttct tcacgggacg ttagagatcg tagaagaaac aaccccagtc acattatttt
    64141 taggcgaaga tgaacagaga gtgttatctg aacgtgtggc taaacttttg ccaaaaattt
    64201 gcagcaatta tacattgata gacacaaaag actatccagt agaaggtatc agtgaaaaat
    64261 atcgcggacg tgttttgtct ttcttattga tgcatgtagt gacacaacgc atcgatgctc
    64321 atgtggagca gttgaactgc catccattag agatacgccg ctactatcgt cagtttgatt
    64381 attaggatag actggataaa aagaatataa aaaataaaga gagcagcgat aactgctccc
    64441 tttatttttt taaaatattg gcatcaatta cgttataaaa cacatttttt gcattatcta
    64501 cagttcaact tataatctgt ttaatgggac atgtgggtgc caaccatttt ttgttatgca
    64561 atagtactat ttagttgttg catggatccg tagtaaaagt ccaagtacaa cgagttgcgc
    64621 cagtttacat agcgttttgt atccagaatg ttgactaaaa caaaagttcc tatgtcaacc
    64681 gtcaacagag acaatctgtc cgttgcagga cctgacagat ttagaaatgt tcaatctgtc
    64741 tcttatgtat tttaaatcaa tactcactag gagaagtttc ctaacctcct aatagtaatg
    64801 ctggtagtaa cattgtcaaa actgcttcct cttaggaaca agcaaagcat aacgagtgta
    64861 aaaataaaat gtagactatt gtaacatatc attgattatt tcaagtaaaa acgataaaag
    64921 aagtaaacaa acacttaaaa acaatggaaa ttagtcccaa ctttaagaaa tgtatactat
    64981 aatggaaatt atcaattatt tatttggagg aatatccatg aaacaaaaaa tcgcagttct
    65041 tggtcctgga tcttggggca ctgctttagc acaaacattg gcagaaaacg ggcatgatgt
    65101 ccgtatttgg ggaaatgtac ctgaacagat tgatgaaatc aataagtatc atacaaatca
    65161 gcatttttta cctgatttga cgatcccaga atcgattatc ggatataaag aattggcaga
    65221 agcagtggat aacgcagatg ctattttatt tgttgttcca acaaaagcga ttcgttcagt
    65281 cgcacaggaa cttattggta aaatgaatac taagccaatc attatacatg caagtaaagg
    65341 actagaacaa gatacgcata aacgaatctc agaagttttg gctgaagaaa ttccagaaga
    65401 aaaaagacag gcaattgttg tattatctgg tcctagccat gctgaggaag tggcagtaca
    65461 tgatatcaca acaattacag ctgcaagtat tgatcaaaaa gcagcagcct atgtacaaaa
    65521 actgttcatg aatgattatt tcaggattta tacaaataat gatgtgattg gcgtagaaac
    65581 tggtgcagca ctgaaaaata tcattgcaat tggtgccggc gctatccatg gattaggatt
    65641 cggagatgat gcaaaagcag caatcatgac tcgaggattg gcagaaatca gccgtcttgg
    65701 tgtcgcgatg ggtgccaatc ctctgacatt tatcggtttg agtggtgtgg gggacttgat
    65761 cgttacttgt acaagtgttc attctcgcaa ttggcgtgcc ggtaacttgt taggacaggg
    65821 acataagctg gaagaagttc tagaaaacat gggaatggtc gttgagggtg tggcaacgac
    65881 aaaagcagca gtagagctag ctcaacagct aggtgttgag atgccaatta ctcaaacaat
    65941 ctataatgtt ttgtataatg gagaagatat caaaaaagca gcaaaagaaa tcatgttacg
    66001 tgacggaaaa atggagaatg aattttctct tcgttaaata gatgatcaat agttaatc
//
LOCUS       DADGKS010000008        65952 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.008, whole genome shotgun sequence.
ACCESSION   DADGKS010000008 DADGKS010000000
VERSION     DADGKS010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 65952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65952
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.008"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            274..840
                     /gene="amaP"
                     /locus_tag="JXV47_000531"
     CDS             274..840
                     /gene="amaP"
                     /locus_tag="JXV47_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAX1486597.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            853..1041
                     /locus_tag="JXV47_000532"
     CDS             853..1041
                     /locus_tag="JXV47_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAX1486598.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            1054..1611
                     /locus_tag="JXV47_000533"
     CDS             1054..1611
                     /locus_tag="JXV47_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAX1486599.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            1643..1885
                     /locus_tag="JXV47_000534"
     CDS             1643..1885
                     /locus_tag="JXV47_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAX1486600.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            2226..3440
                     /locus_tag="JXV47_000535"
     CDS             2226..3440
                     /locus_tag="JXV47_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HAX1486601.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            3471..4898
                     /locus_tag="JXV47_000536"
     CDS             3471..4898
                     /locus_tag="JXV47_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAX1486602.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            4921..5847
                     /gene="glsA"
                     /locus_tag="JXV47_000537"
     CDS             4921..5847
                     /gene="glsA"
                     /locus_tag="JXV47_000537"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HAX1486603.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            6055..7515
                     /locus_tag="JXV47_000538"
     CDS             6055..7515
                     /locus_tag="JXV47_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486604.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            7736..9499
                     /locus_tag="JXV47_000539"
     CDS             7736..9499
                     /locus_tag="JXV47_000539"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HAX1486605.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            9583..10041
                     /locus_tag="JXV47_000540"
     CDS             9583..10041
                     /locus_tag="JXV47_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HAX1486606.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            10150..10833
                     /locus_tag="JXV47_000541"
     CDS             10150..10833
                     /locus_tag="JXV47_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAX1486607.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            10980..11594
                     /locus_tag="JXV47_000542"
     CDS             10980..11594
                     /locus_tag="JXV47_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HAX1486608.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            11610..11816
                     /locus_tag="JXV47_000543"
     CDS             11610..11816
                     /locus_tag="JXV47_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486609.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            12355..12912
                     /locus_tag="JXV47_000544"
                     /pseudo
     CDS             12355..12912
                     /locus_tag="JXV47_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     gene            12970..15009
                     /locus_tag="JXV47_000545"
     CDS             12970..15009
                     /locus_tag="JXV47_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HAX1486610.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKIAFDSLGGKAASTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(15118..16269)
                     /locus_tag="JXV47_000546"
     CDS             complement(15118..16269)
                     /locus_tag="JXV47_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAX1486611.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(16423..16953)
                     /locus_tag="JXV47_000547"
     CDS             complement(16423..16953)
                     /locus_tag="JXV47_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486612.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(17052..17402)
                     /locus_tag="JXV47_000548"
     CDS             complement(17052..17402)
                     /locus_tag="JXV47_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HAX1486613.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(17559..19088)
                     /gene="ahpF"
                     /locus_tag="JXV47_000549"
     CDS             complement(17559..19088)
                     /gene="ahpF"
                     /locus_tag="JXV47_000549"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HAX1486614.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(19098..19661)
                     /gene="ahpC"
                     /locus_tag="JXV47_000550"
     CDS             complement(19098..19661)
                     /gene="ahpC"
                     /locus_tag="JXV47_000550"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003756453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HAX1486615.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(19805..20467)
                     /locus_tag="JXV47_000551"
     CDS             complement(19805..20467)
                     /locus_tag="JXV47_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAX1486616.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            20651..22297
                     /locus_tag="JXV47_000552"
     CDS             20651..22297
                     /locus_tag="JXV47_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAX1486617.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            22288..23370
                     /gene="uxuA"
                     /locus_tag="JXV47_000553"
     CDS             22288..23370
                     /gene="uxuA"
                     /locus_tag="JXV47_000553"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAX1486618.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNEYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(23478..25031)
                     /locus_tag="JXV47_000554"
     CDS             complement(23478..25031)
                     /locus_tag="JXV47_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAX1486619.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGMIDKL
                     YFLLKICKENFPATSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVNILA
                     RLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYSLAF
                     ARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPVILE
                     KENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKIQND
                     FMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMDQ
                     SKKENQVTS"
     gene            25179..26467
                     /locus_tag="JXV47_000555"
                     /pseudo
     CDS             25179..26467
                     /locus_tag="JXV47_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(26593..27672)
                     /locus_tag="JXV47_000556"
     CDS             complement(26593..27672)
                     /locus_tag="JXV47_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAX1486620.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(27775..28215)
                     /locus_tag="JXV47_000557"
     CDS             complement(27775..28215)
                     /locus_tag="JXV47_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAX1486621.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(28272..28682)
                     /locus_tag="JXV47_000558"
     CDS             complement(28272..28682)
                     /locus_tag="JXV47_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAX1486622.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(28862..29296)
                     /locus_tag="JXV47_000559"
     CDS             complement(28862..29296)
                     /locus_tag="JXV47_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAX1486623.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(29396..30244)
                     /locus_tag="JXV47_000560"
     CDS             complement(29396..30244)
                     /locus_tag="JXV47_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAX1486624.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            30633..32399
                     /locus_tag="JXV47_000561"
     CDS             30633..32399
                     /locus_tag="JXV47_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HAX1486625.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            32501..33760
                     /locus_tag="JXV47_000562"
     CDS             32501..33760
                     /locus_tag="JXV47_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAX1486626.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            33907..35208
                     /locus_tag="JXV47_000563"
     CDS             33907..35208
                     /locus_tag="JXV47_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1486627.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            35211..36062
                     /locus_tag="JXV47_000564"
     CDS             35211..36062
                     /locus_tag="JXV47_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1486628.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            36075..36890
                     /locus_tag="JXV47_000565"
     CDS             36075..36890
                     /locus_tag="JXV47_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HAX1486629.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            37041..38207
                     /locus_tag="JXV47_000566"
     CDS             37041..38207
                     /locus_tag="JXV47_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAX1486630.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            38437..39084
                     /locus_tag="JXV47_000567"
     CDS             38437..39084
                     /locus_tag="JXV47_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HAX1486631.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            39168..40112
                     /locus_tag="JXV47_000568"
     CDS             39168..40112
                     /locus_tag="JXV47_000568"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HAX1486632.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            40247..41698
                     /locus_tag="JXV47_000569"
     CDS             40247..41698
                     /locus_tag="JXV47_000569"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HAX1486633.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            41719..42555
                     /locus_tag="JXV47_000570"
     CDS             41719..42555
                     /locus_tag="JXV47_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAX1486634.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            42555..43214
                     /locus_tag="JXV47_000571"
     CDS             42555..43214
                     /locus_tag="JXV47_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAX1486635.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            43340..44029
                     /locus_tag="JXV47_000572"
     CDS             43340..44029
                     /locus_tag="JXV47_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486636.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            44035..44991
                     /locus_tag="JXV47_000573"
     CDS             44035..44991
                     /locus_tag="JXV47_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HAX1486637.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            45035..45547
                     /locus_tag="JXV47_000574"
     CDS             45035..45547
                     /locus_tag="JXV47_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1486638.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(45803..46351)
                     /locus_tag="JXV47_000575"
     CDS             complement(45803..46351)
                     /locus_tag="JXV47_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAX1486639.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(46440..47621)
                     /locus_tag="JXV47_000576"
     CDS             complement(46440..47621)
                     /locus_tag="JXV47_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HAX1486640.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGLGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(47857..49365)
                     /locus_tag="JXV47_000577"
     CDS             complement(47857..49365)
                     /locus_tag="JXV47_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HAX1486641.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            49524..49715
                     /locus_tag="JXV47_000578"
     CDS             49524..49715
                     /locus_tag="JXV47_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486642.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            49918..50835
                     /locus_tag="JXV47_000579"
     CDS             49918..50835
                     /locus_tag="JXV47_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HAX1486643.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            50828..51901
                     /locus_tag="JXV47_000580"
     CDS             50828..51901
                     /locus_tag="JXV47_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486644.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            52049..52567
                     /locus_tag="JXV47_000581"
     CDS             52049..52567
                     /locus_tag="JXV47_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486645.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            52548..52940
                     /locus_tag="JXV47_000582"
     CDS             52548..52940
                     /locus_tag="JXV47_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HAX1486646.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            53016..53951
                     /locus_tag="JXV47_000583"
     CDS             53016..53951
                     /locus_tag="JXV47_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HAX1486647.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            54084..54863
                     /locus_tag="JXV47_000584"
     CDS             54084..54863
                     /locus_tag="JXV47_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HAX1486648.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            54856..55173
                     /locus_tag="JXV47_000585"
     CDS             54856..55173
                     /locus_tag="JXV47_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAX1486649.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            55417..57027
                     /locus_tag="JXV47_000586"
     CDS             55417..57027
                     /locus_tag="JXV47_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAX1486650.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            57184..58032
                     /locus_tag="JXV47_000587"
     CDS             57184..58032
                     /locus_tag="JXV47_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAX1486651.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            58263..58742
                     /locus_tag="JXV47_000588"
     CDS             58263..58742
                     /locus_tag="JXV47_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486652.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            58775..61003
                     /locus_tag="JXV47_000589"
     CDS             58775..61003
                     /locus_tag="JXV47_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAX1486653.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            61132..62775
                     /locus_tag="JXV47_000590"
     CDS             61132..62775
                     /locus_tag="JXV47_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAX1486654.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(62848..63393)
                     /locus_tag="JXV47_000591"
     CDS             complement(62848..63393)
                     /locus_tag="JXV47_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HAX1486655.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(63416..63901)
                     /locus_tag="JXV47_000592"
     CDS             complement(63416..63901)
                     /locus_tag="JXV47_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAX1486656.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(63891..64703)
                     /locus_tag="JXV47_000593"
     CDS             complement(63891..64703)
                     /locus_tag="JXV47_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HAX1486657.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(64842..>65952)
                     /locus_tag="JXV47_000594"
     CDS             complement(64842..>65952)
                     /locus_tag="JXV47_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HAX1486658.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT        22010 a        11768 c        12893 g        19281 t
ORIGIN      
        1 aaataaatag aatcttgtaa taataactga gcataatctt tgcaattttt aatcttgaat
       61 aatatccttt aagtatagcc agcaatcaaa agtaaataga gaataagtaa gcaattgtta
      121 tttcagtatc agactggcaa taaaacgccg ttatgatcca gcaatgtttg gtagcgcttt
      181 atttactgat gctatgctaa ctgttcgcta tctatactgt gattgtcggt agagttattt
      241 acagggtaaa aataagttta taggaggtgg aaaatgaata aggggttaaa aataatcggt
      301 gttatcatga gtttactgct actttcagta tttctagcga ttgcgttgat caatgcgccg
      361 tatattatgc ctgaacaatt ggaacgattt cgcttcttta ctttaacgaa ttactacatg
      421 caacaatata ttttctgggc agctgtagta tttgccgttc ttgctattat catcttgcta
      481 gtcgttcttt tctatccaaa gtcaagagga actttcgtta tgaaacggga agatggcaaa
      541 ctaacaatcg acaaaaaagc gatcgaaggg ttggtacgtt cccatttaca cgaagaagag
      601 ttcattcatt cacctaaagt acggatacgt tcaacgaaaa atcgaatcca tatccatgtc
      661 aacggagact tgaaacgaac ttcttcatta gtagggaaaa caggtgtatt gatgcaagat
      721 atcgaagaag aagtaactaa agtactcgga acaaaagaaa cggtcaaagt ggcagtcaca
      781 tacagcggtt atgaagaaca agaagataca agagactaca agcactctcg agtggaatag
      841 gagggccaaa taatgaaaga actattttca gcatacaagc tccctattat ctttgggggt
      901 cttggactac tgctagctgt tttatggtta acgattggat ttttcaagac attgttgatc
      961 ataatcatga cagcaattgg cgcaggaatc ggtttttatt tgaaacagtc aggaatagtt
     1021 gatcaatttt ttaaatcata ggaggaaaca aagatggaaa acaaaaacat gaatacaaca
     1081 aatggatcag ttttggcaaa tgaaaaagga gaaaaccgca tgatgaatgg tgaattgact
     1141 tatgaagaca aagtcatcca aaaaatcatc ggttatgcat tgaaagatgt agatggtcta
     1201 ttgacattag atggcggatt tttctcaaat atggctgaaa aattagtcaa cacagataac
     1261 gtaacagcag gtatcaatac agaagtaggt aagaaacaag tagctgtgga tctagatgtg
     1321 atcgtagaat acggtaaaga catcgaagat atttacaacc aaatcaaaga attgatcagt
     1381 actgaagtaa acaatatgac acatttagat gttatcgaag tgaatgtgaa tgttgcagac
     1441 atcaaaacac aagaagaata ccaaaaagat caagaaacag tacaagacaa agtaacagaa
     1501 gcagcaaaat ccacaggaca atttgcttca cgccaaacag ataaagcaaa atctgctgta
     1561 ggcaaaggtg cacaaaaagt caaagaaaat aacgaaccac gtgtacaata agaagtaaga
     1621 agtcagttag gaggaattta aaatgggatt tatttgggca ttaatcgtcg gcggtatcat
     1681 tggagcaatt gcaggagcaa tcacgaataa aggatcatca atggggatca tcgcaaacat
     1741 cattgctggt ttagtaggtt cagcaattgg acaagcttta ctaggaactt ggggaccaac
     1801 aattgcagga atggctatca ttccatcatt gatcggtgca atcattttag tattagtcgt
     1861 ttcattcttt gcacgtaaat tataagcaaa ttgaagaaaa acttatgttg aaatgaagaa
     1921 caaatttgag aaccgtagcg acactcgctg cggttctttt ttatatattt tatatgaagt
     1981 attctttatt ccttatgaaa aaatatcttt aaaaataaaa aaagacgaaa ataaacggtt
     2041 ttctataaaa agaagaccgt ttattttttg tctttatttg tgtgaaaaac gaaaaagagc
     2101 acaacacatc aagcttttat taattgtctg tcttttataa atgcaagtat taattcaaaa
     2161 aaacagaaga aaaaaacaac tacaccttct tttatactcg taatcgtaga aaggaggcga
     2221 aaaaaatgaa tacattacct atcaatacag gagatacagc attcatgatt ttatgtacag
     2281 caatggtttg cctgatgact cctggtctag ctttttttta cggcggatta gcacggaaga
     2341 ataatatact aacgatcatg tctcaatctt ttctctccgt tgggataaca acgattatgt
     2401 gggtatttgg tggattcgga ttggcctttg gacgggatat cggcggtgtt attggaaacc
     2461 cggcagattt ctttttgatg agacatgtta caagcttccc caacatgttt catggtgcaa
     2521 cgattccatt tttaatgttc tttctttacc aactgatgtt tatcgtgatt accgttcctt
     2581 tgatgacagg agcttttgca gggagattga atttaaaagg ctatattata cttgttattt
     2641 tttggaatct gctgatttat ttccctgttt gccactggat atggggtggc ggatttttgg
     2701 atcagatggg atttagagat ttcgctggtg gagcagtcat ccacacgaca gctggattcg
     2761 gctctttagc atgtatcctc acacttggtc aaagaaagat tcctttagga gaaagaagtc
     2821 agcatagcag tcttatggca gctgctatcg gtacaggact gctttggttt ggctggttcg
     2881 gttttaattc cggtggtgca cttcgagcag atgaacaagc agtcaatgca tttggttcaa
     2941 cattcatcgc tcttgcattt gcgatgatta cttggctgat cattgcaaaa gtaaaaggaa
     3001 atggctttga ttttgtcgac gtactaacag gatccgttgc tggattggca gccattacgc
     3061 cttgtgccgg ttatgtagaa gcaaaaagtg ccatgctgat tgggatcatt gcgggtatcg
     3121 tctgtcatgc tgctgttgat tttcgtaaaa agaaacaatg ggatgatgca cttgatgtgt
     3181 ggggtgttca tggcatgggc ggattcacag gtacgattct gatagggatc tttgcatcta
     3241 acagccattt actaacgaat ccaagcagct ggtacttctt agggattcaa gtgattggtg
     3301 tcatcattac tgccgtgtat gcctatgtgc tgacaacagt gattttaaaa tcggcgatgc
     3361 actttacaac gatcactact acaaaagaag aacaagaaga aggattggac tttttcttct
     3421 ttggcaacaa actcaattga aacaaattca aatagaaaag aggaagattc atgcaacaaa
     3481 gcaaaacgaa aattcctgca aaaaaattaa cgttctttgg ctttttggct atgaccatct
     3541 caatggtcgt ttcattatat gaatatccca cattcgcgac ctcaggcttc agcttagtat
     3601 ttttcttgtt attaggcggt ttgctatggt ttatccctgt ggcattgtgc gcagcagaga
     3661 tggcaacggt gaaaggatgg gaaaaaggcg gtgtctatac ttgggtcagt cgcacattgg
     3721 gaaaacgatt cggttttgcc gcaatctttt tccaatggtt tgagataaca gttggctact
     3781 tgaccatgct gtatttctta actggtgcat tatcctatgc aacgggtatt ggtgctatac
     3841 aaaacaataa atatctgaaa ttggcaatcc tattgattat tttctgggct attttactct
     3901 cacagttaaa aggaaccaaa tacacttcat tgattgctcg gatcggtttt gtagctggta
     3961 tcttgttgcc agcattagtc ttgtttggct tagggatcca ttatgtcgct tcaggcgctc
     4021 cactacaaac gatactgtct atgaaaacat tgattcctga tttttcgaaa ttgcctacgc
     4081 tggttgtttt tgtttccttt attttagcat atatgggcgt agaaacatct gccagtcatg
     4141 caaatgaaat ggaaaaccct aaaaaggatt atccattagc aatgtttgta ttggttattc
     4201 tggcaatcat tttagatact tttggcggat tgaccgtcgc tactacagta cctcaacatg
     4261 gtttgtctct taatacaggg gtgattcaat cgttagaatt cctattaaga cacattgatc
     4321 caaatcttgc atggattgcg aaaattcttg cgattcttgt ttgtttaggt gtcatcggag
     4381 aaattgcttc ttgggtaacc tctccttcaa aagcacttca cgtagcagca gaagaaggat
     4441 tacttcctga atattttgca aaagaaaaca cacacggtgt tcctgctcat ttgatgatcg
     4501 caaatgggat cgttgcaaca atctgggcag ccgtctttac attaagcggc ggggggaata
     4561 atctttcatt tcttgcagcg atgtcattga ctgttgtaat ctacctgatg ttgtacttta
     4621 tgtttttcgc gggctatttg aagctggttt ttaaagatga cagtcttgaa agagcctatc
     4681 aggttccagg cggaaaagtt gtaaaagtaa tcgttgcttg tttaggtctt ttgacttcac
     4741 tttttgcttt ttgtatctca tttgttccac ctgctagtat cgcagctgga cagcatggga
     4801 tttatgaaac gattctgatt gtttcttatc ttatcgtctt agttattcca tttacgatct
     4861 acgcatgccg tcataaattc cagcatgcag aaaaataaaa aatgaaagct ggttattcaa
     4921 atggaagtaa aagaattaga acaattgatt ggaaaaaatt tccactatta tcaaacagga
     4981 caagtggcgg attacattcc agcattagct gaagtggatc ccaaacaatt aggtatggcg
     5041 atttatgatt tggatacaaa acaactgatt gagggaggag acgccgatgt gcgctttgcc
     5101 atcgaaagca tgtcaaaagt tcccgtattg ttattagcaa tcaaagacaa cggaatagaa
     5161 aaagtctttc aaacaatcaa cacggaacca accggttttg ccttcaattc tatcatgaat
     5221 atggaaatca atcatcgcaa acatccaatg aatccttttg ttaatgcagg agcgattgca
     5281 acaacctcgt tgattgccgg taaagatgca gatgaaaaat ttgagcgaat cttgtcattt
     5341 atgaaagaga tctgtgatga tcctaatatc acattgaatg aagaaatcta tcattctgaa
     5401 tcaagaacag gtgatatcaa tcgctctctt gcttactata tgaaaggtaa tcaaatgatc
     5461 gaaggagacg taccggagat actcgatgct tatttcagac aatgctccct caatgtcacc
     5521 gctacaggca tagcaaaatt agctgctgtg ctggcaaata aaggaattgc tccttggaat
     5581 ggcaaacaaa tcattactga agaaagtgct acaatcgtca aatcaattat gacaactgct
     5641 ggtttgtatg atgaatcagg agagttttcc gtccatgttg gtgtacctgc aaaaagcggt
     5701 gtaggcggcg ggttgatggc agctgtgcca aatcgttacg gcataggtgt cttcagcccg
     5761 gcactagatc catttggtaa cagcgcagct ggtatccaat tgttgaaaga tgtagtcaaa
     5821 gaactagacg ctgacatctt tgaataacca ttcttgaaag aggctggggt aaaagtccaa
     5881 acggctcaaa gctacctaca atgaggctga aattgtgagc ttgtttgact tttgtcccag
     5941 tttctttttt tattggtttt tgaaagggct tttctaaata aaaaggaaac aaaaatacga
     6001 tttacagata tgattaaata aaatcataag aaaaactgga ggcgtgtatc aggaatgctg
     6061 gaaaattaca tcgagcgaaa tatatttaga aaagtgtatc tgtgtgaaca attatttgaa
     6121 ttccaagaaa tagacatcga acaaacagct atttctctaa gggtgactac accaacgatc
     6181 cttcacgatc tagaaagtct agccgagtgt ctagaatatt gtataaaaga acaagtaaga
     6241 gagaagcata agtataaact cgtattcaaa catggtattg ctctttctga gctcacacag
     6301 tttctgtacg gtcaatctta ttttttaaag tttttaagtt attattttaa tggtatattc
     6361 acgagtacag aactggctga tcttgaattt atttctttga gcaaagtata tacaatcaaa
     6421 aaaatcgtat tggatttttt taaagaaaat gattatttga aaaataaaga aatcattatc
     6481 ccagaatttg actcgcggaa catcttgcta gctttagtac gttatgtcaa ttgggaaggc
     6541 tatgaaaata aaaatccgta tgtagaagaa gcttgtaacg agttgattga ttatgtagag
     6601 actcattttt ttaaaagaag atattcggaa gatgaaaagt cctttatcat acgaggaata
     6661 gagatcgcaa tcggaagaaa ggcatttccc cttggactga aagaagaaga taagaaaagc
     6721 gcagaaacga agccgttatt tcaattagtc tgtcaaggat tggaagagca aaaaggaatt
     6781 ctagacttac aagaagaaga tgtctattat attttttctt tgttcaacag tagaaattat
     6841 accaatgaga acatggagct gttaagaaaa gatttcgaag ttgtttataa aaattttgtt
     6901 ctcaatgacc tatcactgaa tgaattgatt ttacagatta ttagtatcgc tgaaatcgac
     6961 gatgcagaaa attttatttt caagcaatcc tttttacaat ttgtccgtac gttgtgggca
     7021 gatggacaag tatttttacc ggaaaggatc tatcttctat cagaaaaaga acaacttctg
     7081 tacggaaaaa ttgtagaaat attggaagag tggaaaaaga aaaatcaaat ccaactaaga
     7141 tggaatgaaa atttcattcg aaaattcgtc aaaagtcttt ctttgatcaa cagtgaacaa
     7201 gcggggagac aggaaataga aatttttgtt gtttcagaaa gttcagtcaa acaatttttt
     7261 tatcgaaccc aatttcattt gtatgcggaa gaaggcatcg ctgaaataaa tcctatttta
     7321 tttcgttcat tagaagaatt gcctgatgaa tgtctatgtg cgaaaaaaag agtggttttg
     7381 tgcgatgctg ctagctatca aaatggatta gaaactgaaa agacaaagat ctatccaatc
     7441 tcattaaaag gtgcaaacat ccatttgtat catattgctc aggaacttca cctattaaaa
     7501 aaacatattt cttgatgaga ccttaattag gagaccttct acaaagcttt ttaattgtct
     7561 gtagaaggtt tttatttgag tcctgattcg tgcgaagatc tacttatata acaagctttc
     7621 tctgaaattt ttttaaaatg ctattgactt agagtcaact ctaagtagta gaatagataa
     7681 agtgtaacaa atctattttc attaaaagaa gatagtacgg aggagagaat gtattatgag
     7741 tacagtatta catgtattgg atgcaatcaa tagccccgca gatgtcaaaa aattatctgt
     7801 tgaggaaatg aaacagttgg cagaagagat gcgccaaaaa atcttgcaaa aggacagcga
     7861 tgtaggtggg cacgttggtc cgaatctagg tgtagtagaa ttaacgattg cgtttcatta
     7921 tgtatttgat tcaccaaagg ataaaatcgt ttgggatgtt tcccatcagt cttatggtca
     7981 taagctttta actggtcgaa aaaatggttt tgaaaaagga cattaccgtg aagtgagcgg
     8041 atattccaac caacatgaaa gtaaacatga ctattttaca gtggggcaca catctacatc
     8101 tatcagctta gcaacaggtt tagctaaagc gagagatctg aagaaagaat caggaaatgt
     8161 ggtagcattt atcggtgacg gctccctaag tggtggctta gcttttgaag gattgaacaa
     8221 tggtggtgtt ttacaatcca atctaatcgt attagtaaac gataatgaga tgtctattga
     8281 tgagaatcat ggcagtttat ataaaaactt agctgagctt cgtcaaacca acggtaaaag
     8341 cagcaataac ctatttaaag caatgggatt tgattatcgt tacgtggata atggaaacga
     8401 tctggaaacg gtgatccgtt tatttgaaga agtaaaagat attgatcatc cgattgtact
     8461 tcacgtccat acggaaaaag gtcgcggtta tcagccggca atcgataata aaatgaaata
     8521 tcattggcat gtaccatttg atctgtccac cggggaggca aagcaagtaa cttctggaga
     8581 aacatttaat atgatcatca tggattattt ggataagaaa atgcaaacaa gtacagctcc
     8641 tattgccgca gtcaatgcag cgataccagg cgcctttgga ctgaaaacat tccaagaaaa
     8701 acatccagat cattattttg acgtggggat cgctgaacag cactctatca ctttcgcttc
     8761 tgctttggct tctcagggag tacgtccagt cgtcttccaa tcaagtactt tcttgcaacg
     8821 ggcatatgat caattatcac atgatttagc gatcaacgag aatccagtga ttattttagt
     8881 cggtggcgga acgatctcag ctagtgaccg aacacaccaa ggaacatttg acattcctta
     8941 cttatcaagt atcccgaaca tcaaatatct tgctccagca acaaaagagg atatgatctc
     9001 tatgctagat tgggcgttcg aacaaacagc gcagcctgta gcaatccgaa ttcctacaca
     9061 tggtgtagaa catggtacag ctatcgcaaa tgattatagt attccagcct atcaaacagt
     9121 aaataatgga ggaaaagtag caattttagc tttaggcggt tttcttgaat taggaaaaga
     9181 aacagtaaaa gcttttagaa aaaaaggaat cgaagcaacg ttgatcaatc caggaacgat
     9241 cacagaaaat gacgtagaaa cattagataa attaaaagaa acacacgaat tagtcatcac
     9301 attagaagat ggtagtttgt caggaggatt tggcgaaaat atcagtcgtt attatggtga
     9361 ttcttcaatg aacgtattaa attttggtgc agagaaagaa ttcacggata gcgttcctgt
     9421 agggcagctt tatgaacgtt atcatttaac accaaaacaa atcgttgaag atagtctgcg
     9481 tgtcttgaat attcaataat tcattatgct caccatccag ataattgttt atactagtat
     9541 ctggatggtt ttttcattat aaaaagcaaa ggggtggatg ttatgtatca gcaagtagaa
     9601 gaatatgtca aaaagttcca agaaaaatat cctagttatc aatcagaaaa attaggtttc
     9661 ttttcatttg gggatacaga aaaaatggca gacgagttga gcgaactagt tgtaaaaaag
     9721 ataaagactg gtacatcaag tggttacgat ctgtataaac aagagaatga gcctttacca
     9781 aaagttggtc aattagacgt ggtcctgaat ggaaaaaatg aaccagtttg tatcatcaaa
     9841 aatataaatg tgaccatctt gccttttagt gaagtcacga aagagcatgc ttggaaagaa
     9901 ggagaagggg atcggacatt agcttattgg cggaaagtcc atgctgagtt ttttaaacat
     9961 gcttataaag aagcgttgaa catagaattt acagaagaga agctggtcgt atacgaagaa
    10021 tttgaagtaa ttttctttta gtaagaaagg tctgctgaaa gaaatagctc attattgtct
    10081 cctgaataga aaagggttac atttttatat gaagctgtat ttttatataa cattactgga
    10141 ggagatattg tggatacact ggaacaaatc aaaggcggag tcgtcgtttc ttgtcaagct
    10201 ttggaaaacg agccgctaca cagttctttt attatgggga gaatggcttt ggctgcaaaa
    10261 gaaggcggag cagttggtat tcgagcaaat acgacagaag atatcaatga aatcaagcga
    10321 atcgttgatt taccggtaat agggattatc aaaagagatt acgatgggtc agaagtgttt
    10381 attactgcga cagaaaaaga agtggaagaa cttttggaga cgcaagcaga aatcattgca
    10441 ctggatgcaa cttctcgtaa acgtccgaca gaaaaaacaa ctgctgaact tgtccaaatg
    10501 attcacgaac acggtcggtt agctatggca gatatttcga cttttgagga agcgcttcaa
    10561 gcgcaagaag atggttttga tcttttgtct acgactttag caggctatac agaatattca
    10621 cgaaagacgc agacacctga ttttgattta ttgaatcaaa tcatagaaca agtcgatatc
    10681 ccagtaatta tggaaggaca tactgactct cctgaacaag tagagaaagc atatgaatta
    10741 ggtgcttttt cagtcgtagt tggatctatt atcacccgtc cgcaattgat cactaaaaga
    10801 tatgtcgaag ccgcaagtaa agcaaataac taaaaaacac gcacggcaca gattcttgac
    10861 aaaaaagaaa aattgataga tagtttaaag cagattctaa gaagatgaaa aaagcattac
    10921 ttttcatttt gtcttcaaga tctgcttttt aacgaatttt atagaaagaa ggcgaaacca
    10981 tgtttgaacg gagtccttca gaattgacag aacgtgaaaa ttacaagttg ctgattggtt
    11041 cagtcatccc tagaccagta gcagtagtaa cgactaaatc agcaaaagat atagtgaata
    11101 tcgcaccctt cagttacttc aatatcgtca gttcgaatcg acccatctta tccttggcga
    11161 tccagagaaa acaagatgca gtaaaagaca cagcaaagaa tattcttgag acaagagaag
    11221 ctgttatcca tatccttgat gaggacaacg tagaagaagt aaataaaaca gcagccaatc
    11281 tgcctaatga ggaaagcgaa ctgtacctga ctgacttgac tttaactgat tcagtaatca
    11341 tttcagtacc agcattgaca gaagcaaaag ttcgttttga aacatcctta tatgaacatg
    11401 tcgagatacg gaataaaaat aaagtaacag ctgatttatt tttgctagaa gtacagaaat
    11461 atcatttaaa tgaaacagtc tatgatgata agacaggaag gatcgatcca agaaaattga
    11521 atgctgtaag ccgtttggca ggaaatgatt atgcagcaat aggagaaatt ttcacgattg
    11581 cacgtcccga ataaaaagga gcactagtta tgttaaaaat aagctataaa ccatcgacag
    11641 attcaaaaga aatgaaaaaa gaatatgaaa cagtgaatga ttttctgcaa gggcagtact
    11701 tagaagttcc gccattgcaa gaccattttg tcgttactac tgttacttta gatggtaagg
    11761 aaatagaaat gccagatcaa acgattagcg gattgtttaa ttactttaac aaataaatat
    11821 ttattccgaa aagtgaaaaa acatataaaa aaacacataa aactaaaaaa ttatcaaaga
    11881 atcctggtgc aactgaaaga atttgcaacg ggattctttc aacttatttg ttattttttt
    11941 ctaaaaaata ttaaagattg ttaaatttca ctatttcatt tcaaattcca ttgcctaatc
    12001 attaggaaaa gtctatcatg aactcgtaaa tagaatatag taataacctt gttaggtgag
    12061 gctcctatac aaacataggc tgttgcccag aaacgtcgaa agtcgccaat gggtaaaaca
    12121 gaaactgttg gattaaggct ttttccaata gctaagaatg ttttctttac gttgtatagt
    12181 gctaaaactc ggacgatgag atgatgctag gtcagaattc ttgttcgaaa aggtttctga
    12241 ccttttcttt atatttttgt gactgactta tttgatgaga caaactcgct cctcacctga
    12301 caagtggatt gctgtgtgag gaggagatgc ggtgaaaaaa gatcgattgg tggaggtcgc
    12361 tcggattcac ttctggttgc acaatacaac cagaaaacac aacaagcaaa actgatctct
    12421 atcatgagag attcatatgt cgatattcca ggttacggaa tgaataagat aaatgcagct
    12481 tactcttatg ggggagttga tttattaaat caaacattaa aggaaaattt caaatttgaa
    12541 gctccctatt atgcaagtat cacatttcaa gattttatcg attgcgttaa tgaactgttt
    12601 cctggtggag tcaagatcga tgcagaaaaa tctctagatt tagatggcgt atatataaac
    12661 aaaggagagc aagtgatgga tggtaatact ttactccagt atgctcgatt tcgggaagac
    12721 aaagaaggag acttcgggag gatcagaagg cagcagcaag tgatcaaagc tatctctcag
    12781 cagctgaaag acgtaacttc aatattcaag ctacccaaag cggttgggaa attacttggt
    12841 agtatccaaa cgaaccttcc agaaagtgtg cttctggatt gtggtatgga tttcctcaaa
    12901 gacatatgtt agaataaaca ggtataaata gtgaaataaa ggaatgacaa gcaagagaag
    12961 gaggaaaaaa tgaaaagaag tgacaagcac ggcaaaaatc gaacaggcgc ttatattgcc
    13021 ggcgcagtga tcttaatagc agctgcgggt ggcggttatt tttactacca gcactatcaa
    13081 gaaacccaag cagtagaagc tggagaaaag acagttgagc aatttgtcca agctttgaac
    13141 aagggagatt ataacaaagc tgcagaaatg acatcaaaaa aggcggcaaa taaaagtgca
    13201 ttatctgaaa aagagatctt agataaatac cagaatatat acggtgctgc tgatgtcaaa
    13261 ggacttcaga tatcgaatct aaaagtagat aaaaaagacg attctactta cagtttttca
    13321 tataaagcaa agatgaatac ctcattaggt gaattgaaag atctttctta taaaggaaca
    13381 ttagacagaa atgatggtca aaccacgatc aactggcaac ccaacttggt ttttccagaa
    13441 atggaaggaa atgacaaagt aagcctgacc acacaagaag cagcaagagg gaatattata
    13501 gatcgaaatg gtgaaccatt agcaacaaca ggcaaactaa aacaattagg agtcgttcca
    13561 agtaaacttg gagatggagg cgaaaaaaca gccaatatca aagcgattgc ttcctccttc
    13621 gacttaacag aagatgctat caatcaggcg atttcacaaa gctgggtaca acccgattac
    13681 tttgtcccat tgaaaatcat tgatggagca acgccagaac ttccagctgg agctaccatt
    13741 caagaagtag acggcagata ttatcctttg ggtgaagcag ctgctcagct gattggttac
    13801 gtgggagata tcacagcaga agatattgat aagaatccag aattaagcag taatggaaaa
    13861 atcggtcgct caggtttgga gatggctttt gataaggatc ttcgtgggac aacaggtggg
    13921 aaattaagca ttacagatgc agacggtgta gagaaaaaag ttctgatcga acatgaagtt
    13981 caaaatggca aagatatcaa attgacaatc gatgcgaagg cacaaaaaat agcttttgac
    14041 agtctaggag gaaaagctgc atcaactgtt gcgacaacgc caaaaaccgg tgatcttctt
    14101 gcgcttgcta gctctccaag ctatgatcca aacaaaatga caaacgggat ctcacaagaa
    14161 gattacaaag cttatgaaga aaatcctgaa catccattca tcagccgatt tgcgacaggt
    14221 tatgctcctg gatctacgtt taaaatgatt acagcagcaa tcggtctcga caacggcact
    14281 atcgatccaa atgaagtgtt gacgatcaac gggcttaaat ggcaaaaaga cagttcttgg
    14341 ggatctttta aaacaacgcg tgtcagtagt gatgtatcac aagtagactt aaaaactgct
    14401 ttgatctatt ccgataatat atatgcggca caagaaacgt tgaaaatggg tgagaaaaaa
    14461 tttcgtacag gcttagataa attcattttt ggtgaagacc ttgatttgcc aattagtatg
    14521 aatccagcac aaatttctaa tgaagatagc tttaactcag atatcttgct agctgatact
    14581 ggatatggac agggcgaact tctaattact cctatccagc aagcagcaat gtattctgtt
    14641 tttaccaaca atggcacact tgtctatcct aaattgattg cagataaaga gacaaaagat
    14701 aagaagaatg tcatcagcga aacagcagta caaacgatcg tgccagatct gagagaagtt
    14761 gtgcaagatg taaatggtac agcacattct ctttctgctt tagggattcc gttggcagcg
    14821 aaaactggta cagcggaaat caaagaaaaa caggatgtaa aggggcaaga gaacagtttc
    14881 ttgtttgctt tcaatcttga taaccaaggt tatatgatgg tcagcatgtt ggaaaataaa
    14941 gaagatgatg attcagcaac caaacgagca tcggaactat tgcaatacct caaccaaaat
    15001 tatcaataaa aaattgcttt ttaagtacag taaaaggact gtggcgttat cgtcacagtc
    15061 cttttttcaa ataaacggtt ttcacgatgt ctctttcaca acttcttttt gatttactca
    15121 cacttcataa actttttttg taaaatattt gagaacaagt ggagaaataa gtgtacttaa
    15181 taaaatcacg ataactaaag gtgaatagta ctgtggttcg atcaattgac tttgctgtcc
    15241 aatttgtaaa atgatcaaag ccatttctcc acgcgaaatc ataccagcac cgaccatcaa
    15301 tgaactatgt tgagaaaaac cggcaatctg agcaccaaaa taacctccaa gcaatttggt
    15361 caaaatcgct acaagcgtca atatagaaat aaagagtagt tgttcactaa agtcagaaaa
    15421 atcaacttct aatcctacac tgacaaaaaa tactggtata aatactgcat atcctaaagc
    15481 ctctacattg tggtatactt cttctttaac ctttgtctga ctgacagcta tcccagcaaa
    15541 aaaagcacca atgacagagc taagcccaac aagatccgct acgtaagaca ttcctaaaca
    15601 aataactagc gatacgatga taatagaaga atttgcgtac actttttctg caaatgaaag
    15661 taggaaaggc gcaatccatt tgactaataa gaaaataaaa acaaaataaa ttagctgttc
    15721 aatcaaaaca agcggtaaag aagcattgct agaagcttcc cccgttagaa aagataggct
    15781 gaaacttaga actaaaacga ctaaaatgtc atctaccaca gaagcaccca aaattgttga
    15841 tccttctttt gtattcacta cgtttagttc ttttaatact tctactgaaa tactgacaga
    15901 agttgccgca agaataatcc caaagaaaat cgcttcattt cccgaaactt ggaatgcttt
    15961 gcctgtcaac cagccaaaaa caaccgggaa gatgatccca agcaaagcaa cgaacatacc
    16021 aggtcggaaa tattttttca aaagagataa atcactttcc agaccagcta aaaacattaa
    16081 taagatcaca ccaatctccg aaaagtcatg gactagaata tcaggtttga cccaattcaa
    16141 tccagcttgg cctagcaaaa caccaacaag taattgtcca atcactgctg ggatacctaa
    16201 tctccgcgag atatgtgagc caatcgttgt tgaaatcaat atcaggcata aaataccaat
    16261 aaattccatt ctcatcattc ctttgtataa aatatagccc gaacttagca taacatacat
    16321 tattgaaaaa ataggaaaat atactcacaa aaaaaccaac aatccaaaag atttttttgg
    16381 attgttggtt tttatacggt ctattttaat aactaaaaat gattaacgta tagtcatttt
    16441 tcttattctg atgaaattga taatctcctg gatgcccatg aaaatcaaaa taaagccgaa
    16501 tatttggaat agaagcatca aacttttgaa tggattgaac aataagacga atccgccaat
    16561 caacaacaga atactactat aaacactcca acttttagct tttgtattca tgctgaagaa
    16621 caactggaac aagctgttga tgataacagc taatccaaga agaatcggca ggatagaaac
    16681 gattgcaggt gcaaaagcat agacgatcag agctaagatc aggaaaaaaa gaccactgaa
    16741 cagaccgata ctccaagaac ctgttttcct tttaaaacgg taagcctcaa aaagattcaa
    16801 caacccaagc aaaacaagat aggcggtgat cagataaccg ataaaatgaa aaacagcaga
    16861 agggtttagc acaatcgcaa tcccagaaat aatataaaca gcagctctta ataaggcgta
    16921 tttttgaata ttttgtttaa tcgtctcaaa catataagaa aacctccttt gacttatttt
    16981 aacgtgaact agtcatttta ccaaattaaa tgttacaaaa tgagcgaagg agaagaatat
    17041 ctctggaaaa atcaacttct gaggatcttt tccatttttt tgccttttgc tagctcatcg
    17101 atcattttat ctaaataacg aatttctttc atcaagttat cctcgatgtc ttctactcgt
    17161 acaccacaaa caacacctgt aatcaaggaa cgtgaaggat tggggacagg ggcttccgca
    17221 aaaaattgtt cgaaagtcac ttgtttttgt agttgatatt ctagttctgt ttgggaataa
    17281 cccgtcagcc aacaaatgat ttcatctact tcctctttta tacgatcttt tctctccgct
    17341 tttgctacat acataggata aacgcttgca aaacttgtcg taaaaatacg attttgcgcc
    17401 ataatcagtc acctttcttt ttttcaaatt atttactact tatagtatat aagaaaaaga
    17461 gaagaaaaag cgattattca aaaaaacaaa aaggattgtg acaaaattct tgtcaccatc
    17521 cttttttccg ctctctgact ttttacaatc ttcatagctc aagtgcgcat cagataatcg
    17581 aatgctccta aagctgcagt agctcctgaa cccattgaaa caatgatttg tttgtatgga
    17641 ctatctgtac aatcaccagc tgcgaaaacg ccggggatat tcgttgcgcc atttttctcg
    17701 gtcactattt catttcttgg attcatttcg atcgttccat ctagccaatc cgtattaggg
    17761 agtaagccga ctagaatgaa tactcctgaa acagctagtg tatgcatctc catcgtacgg
    17821 cgatcgatat aggagagaga ttctacctga ttcgtaccgc tgatttcttt cgtcgctgca
    17881 tgtttgataa cagtgacatt cgcaagagag actagtttat cctgtaagat ttgatctgct
    17941 tttaattctg gtaagaattc tagaacatat acatgttttg ctaacccagc caaatcgatt
    18001 gctgcttcaa caccagaatt accaccaccg ataacagcaa tctcttttcc tttaaataaa
    18061 gggccgtcac agtgtgggca ataagcaatt cctttatttt taaactcttt ttcgcctggt
    18121 acattgatag aacgccagtg cgcacctgtc gcgatgatgg cggtttttgc tttaagtgat
    18181 ataccgttag ctaagccaat attaataaaa tgttgctctt tatttaagga aacggcctgt
    18241 tgattcatca taatgtcgat agggtaacta cgcacatgac tttctacttg ctgcatcaat
    18301 tttggacctt ctgtgtaaga ggtaccaatc atattttcaa tccctagtgt ttcaacgact
    18361 tgtccgccga aagaatcagc gacaagtcct gtacggattc ctttacgtgc tgcatagata
    18421 gctgcactac tagctgctgg tccaccgcca attactaata catcataagg ttctttttca
    18481 aacaactctt cttcaatcaa agggccagtg attttttcaa caatttgttc gatcgtcatg
    18541 cgtccgctac taaattcttc tccatttaaa aacacagttg gcactgccat gattttttta
    18601 tcatcgattt ctttttggaa catcccacct tcaatcatcg tatgagtaat atttggattt
    18661 aatacagcta atatattcaa tgcctgtaca acgtcggggc aattatgaca agtcaagcta
    18721 acataactgt caaaatgcaa tgtttgtgtt atttttttga ttttaagact caaagattca
    18781 ctgattttcg gtgcccgtcc actaatttgt aacatagcca gtaaaaaaga ggaaaattca
    18841 tgaccgaggg ggataccagc aaaaacgatt ccactttctt tgccaactgg attgatagaa
    18901 aaactaggtg tgcgcatcga atctcttttt tcccaagaga ttttaggaga catttctgct
    18961 atttccttcg taaattcagc tagtttttga ctattttcac tattatccaa actaacagaa
    19021 aaaacaatag gagattcaat cagtgctaaa tattgttcga gattttgttt agtttctttg
    19081 tctaacatat ccaccaccta aatctttcca acaagatcaa aacttggttt caatgtttcg
    19141 ccactttctt tccattttgc cggacaaact tcacctgggt gggtacgtac atattgagca
    19201 gcgcgaatct tatcaatcag tgcactagcg tcacgaccga ttccatctgc attgatttcc
    19261 atagcttgaa cgattccgtc tggatcaata ataaatgttc ctcgctgagc taatccttgc
    19321 tcttcatcca aaacatcaaa aatacgagaa atctgatgag acggatcacc gatcatcacg
    19381 tattcgattt taccgatagc atctgatgta tcatgccatg ctttgtgagt aaagtgggta
    19441 tcggtagagc aagaaaagac ttcaacacct aaagatttca atgtactgta ttgttcttgt
    19501 aagtcttcta attcagtagg acaaacaaaa gtaaaatcag ctggatagaa gcaaagaata
    19561 ctccagttcc ccataagatc tttttcactg acttctaaaa attctccttg atgataagca
    19621 tgtgcattaa attcttcgat ttttttccca atcaatgaca tagtaaaacc tccaataata
    19681 attatttatt tataattatt gtaatttagt tggagttgca aagtcaatgg atattttgtt
    19741 atttaataaa gattactcaa aaacgaaggt taattataaa aatagaagag gtcgcaagaa
    19801 aatgctactg ctggaaatac tcgggataac gttgagtaac agtttcctgt tctttcagca
    19861 tcatgtgtaa gtgcaatccc gtttgaaatc gagcttcttc tggtttttta tcaactaaag
    19921 ccttgagtaa atcataatgt tgttccatga tcgtttccca tggaagcccc tgaatggtca
    19981 ctcgtaacca gcggaaacgt tctaaatggg tattatggtc atctaaccag ttccaaactt
    20041 cttttcttcc tgcaatttcg aaacaagctt catgaaataa attatctgca cggaaaaaag
    20101 cgcgttcgtc atttattttg actgcttttt cttgttcttc taaaatcgtt tctagcacta
    20161 ttcgtgtttg tgtgtccaat ttggaacaac attcaatcat gatttgctct tccaactgtt
    20221 ctcggacaaa gcgagcattt tctgcagaaa caagattaat tttggaaaca tacgtaccac
    20281 tttgaggtat cgtatacacg agttcttgct gacgtagttg aatcaatgct tcgcgaatgg
    20341 gagtccggcc gatagcaaga tgttcctcca gtgccttttc agatattttc cttccaggtt
    20401 ctaagtcagc atagataatt tgtttacgaa tcgcttgata agcttgtgat tgcaagctgc
    20461 ttttcatctt tattcctcca aaatcatttc tatgaacgta gtataacaga agaggtctga
    20521 aaaacaatct ggtatgtcac attaactagt aaatttgtat aaatagtaaa attttggttg
    20581 acatagcgat ttttattgta taaaattcac ttgaatacaa aaactaatat gttagtttag
    20641 gaggggaaaa atgattgatt taaacaactg gaggaacttt atccctgaat tatctcaaaa
    20701 agaagtagaa atacctcatt ttgaccgtgc atcattaaga gaaaatggac aaaaaaatcc
    20761 tgtctggatc catttcggtg gcggaaatct ttatcgagga tttcatgcag aaatcgctca
    20821 acgtttagcg gatctaggcg aattgtccac tggtgtcatt gtttgtgaaa cattcgatga
    20881 agaaataatt gaaagggctt accaagattt tgatgatttg attcttgaag tggtcatgcc
    20941 aagcagtgga gagttcgtca aacgtatatt agctgcgaca gctgacagtc tgtattgtca
    21001 tccagattgt tctgaacact ttgataagat gattcgacac tttgaaaatc ctagtttaca
    21061 attagttact tttgctatta ctgaaaaagg ttatcgattg aaagatacaa ataataaata
    21121 tataggaccg attgcagtcg atataaaaaa tggtccaaag aagccatcac atacaatgag
    21181 tattcttgct gcgctacttt ataaacgttt tttatctgga gcttggccga ttgcacttgt
    21241 ctctacagat aatttttcac aaaacggtag tcaattacgt acttctttgc taacgatcgc
    21301 aaaagaatgg caaaaggaag gttatgtaca aaatacattt atccaatact tatcgaatga
    21361 agaaattgtt gcgtttccat ggacgatgat tgatcgtatc accccgaatc cttccttgtc
    21421 agttagcaaa atgttggcaa aagagggctt ttcaaatatg tcgattttcc aaaccgcaaa
    21481 aggaaataat attgctccat ttgtcaatac agaggacatc cattatttaa tcatggaaga
    21541 tcattttccc aatggacgtc cgaaattcga aaaagctggg gtattcttga ctgatcgtgc
    21601 aacggtagat aaagcagata cgatgaaggt gacgacttgc cttaatcctt tgcatacgtc
    21661 tttagctatt atgggttgtt tactggggta taggagcata gctgaggaga tgaaagatcc
    21721 agatttatcg ctgctagttt ctgaaatcgg gtacaatgaa ggcctcccag ttgtggagtc
    21781 tccaggtatc attgatccaa agatctttct ggaagaagta attactgtgc gcttttctaa
    21841 tccaaatatt cctgatatgc ctcagcgaat cgccacggat acctctcaaa aggtggcgat
    21901 tcgttatggt gagacgatta aaaaatatat ggaaatagaa gttaaagacc cgcagacact
    21961 tgtattcata ccattgactc tcgctgcttg gcttcgatac cttattggca ttgatgatca
    22021 aggaaaacca ttcatcccga gtccagaccc actattgaca gactttcagc ataagctttc
    22081 cgatattcaa ctgggtacgc aagatacatc acatattcat gagaaaatgg ctcctatttt
    22141 gtcaaataaa gaaatttttg gtgtagatct ttaccaagca gagcttggca gaaaaataga
    22201 agaaatgttc atcaagatgg tagcaggacc gaatgccgta cgaaaaacat tacaggatta
    22261 cttacaagaa catggaggaa atttatcatg gaaatgactt ttagatggta cggatcacag
    22321 gaagaaaaga ttaccttaga tgaaatcaga cagattcctg cggtcaaagg gattgtaggc
    22381 acattgatgg atataccagt aggagaggta tggcccaggg agaggatcaa agaactaaaa
    22441 gaagaaattg agtctcgtgg gttaacacta aaagtaattg aaagcgtcaa tgtgcatgat
    22501 gccattaaaa ttggattacc ttcccgtgag cagtatatcg aaaactataa gcagacaatc
    22561 cgaaacttgg cagaatatgg aatagaagtc atctgctata attttatgcc tgtatttgac
    22621 tgggtgaaat ctgaccttga ctaccgctta gaagacggct catccacgtt agcttttata
    22681 tctgatgata ttccagatga tccaagagaa atcgtcgcgc gcatcgaaca ttccagcaat
    22741 gaatttgaat tgccgggatg ggaacctgag cgcttagctc atatcaaatc cttgcttgaa
    22801 gcctatgcat cagtagacga agaaaaactt cgagaaaatt ttgcctattt tctccaatca
    22861 atcatcccaa catgtgaaga ggtaggggtc aaaatggctg tacatccaga tgatccgcca
    22921 tactcgattt ttggattacc tcgaatcgta aagaatcgag aagatttaga ttggttgtgc
    22981 cgcatagtag acagccctta taacggaatc actctttgta cagggagtat tgcagaagat
    23041 ccagaaaatg atgtatatgg gattttagca gaattttgtc aaagagatcg aatcccattt
    23101 gcacatgttc gaaatattaa atttttagct aatcgagatt tctatgaggc accgcataaa
    23161 tccgaatacg gttcattaga catgtaccgc atactaaaaa caatgtatga caacggattt
    23221 aacgaataca tccgtcctga tcatggaaga atgatctgga atgagacagg aagaccagga
    23281 tacggcttat atgatcgagc attaggtgct gtttatctaa atggattatg ggaagcaatc
    23341 gaaaaaggaa acaaaagtaa agataattag tgaaaaaaac tgtaatttta ttatgtaaat
    23401 aagaaggatg ttcaaattct tgatacataa atccggaggt tgttaataag cattcggatt
    23461 tatgtatctt atttggtcta ggaagtaact tgattttctt ttttcgattg atccatgagt
    23521 gcttcttctt ttaattcaaa gatatattct gagatcctca taatcacttt tttccagtct
    23581 tctggtgtga tgattccttt taaaatatag atttttttga tatgagaagg caattgtttc
    23641 aaagggcagt cgctgataac gatgttgcag ttctccataa aatcattttg tattttgatc
    23701 gattcatttg aaaaaatttg ttctatctta acgatcagat ctttactgat ataaaaatca
    23761 cgcgtatagt tcacaccaat cacaattcgc ggctgttttt tgtagcgatc atacaaatgt
    23821 actaggtctt caaccatcca ttgcacattt tccttttcta aaataactgg taacaagtgt
    23881 tgattttgtt ctctgaaatc catataaaat tgttcaatgg cggtttggac ttctttcaac
    23941 acgctatgtt cttgataaag catgaaagta ggaaggggcg tatttggttg attgaagtta
    24001 agaaatccat tataaagttt atttcgtgcg aatgccaatg agtaaagaat cttttctttt
    24061 tcaggtataa acaaatcaaa tacagtacaa aaggactcca ccatttctct tgaataaaga
    24121 acatgaggaa cgtttgcttt ttttaaaagt ttgtattgct ccaagcttgt ttcttccgat
    24181 tcgattttcg tgatagaaag tcgagctaaa atattcacta agatgcgttg ttcgcgacaa
    24241 attggcagat taggtcgcaa aatatctaca gagggatcaa taaaaaagtc aatatattca
    24301 tactctgtga attctttttg tacgtctttc acagaagttg caggaaaatt ctctttacat
    24361 atttttaata gaaaatataa tttatctatc ataccgctat ttagtcggtc aagtacttct
    24421 tttttaaaaa aagtattcat cataaaagcc actacttgcg gatcttcatc ataaaattct
    24481 gtagcagtac ttgaaaagat gttccaataa atatctaatg ctgcatattg aatttgtacc
    24541 tcttttccag aaaaagactt tctgccatta ttagaaaagg agatagacaa accgtacaat
    24601 gctaaaaatg cattaatctt tttcattttc gtatacaaat aagaggcact atagtttgtt
    24661 tgctgactta aactgataat cgaatttgtc tgacagctga acaaagaagt caagatctga
    24721 taactgactg attcgttgca gtatcttcca aatagacgat aatagcagta agccggatca
    24781 attccttcaa aattcaactt taaaaaaggt ttttgcttat caatatgcag ttctgttaga
    24841 ttgagacgct caaagtcttg ttctaattct ttgatgtata gtaaaaaatt tgattcagac
    24901 atatggaaat gatctgctaa atattgtgta gtaataaaga aacgatgttc agataggaaa
    24961 agaaaaatat ctaattttgt attgcttttt ttcttcaaga gaaacgtttt aatcgcttct
    25021 tgagtttgca tgaaagaggc tcctttttac ttaaattgtt aaaacttgaa aatattactg
    25081 tttttttcat aaatttagac aaaaaaacag taaacatata ggtagaatct ctactatctt
    25141 atttcttgca tacaaaaaaa tcaaggagtg agagagttat gagatattca accatcttaa
    25201 tatcaacatt tgcagcctta agcttatcgc ttactataaa tcagacagtc cacacagagg
    25261 agatagaaac agccaaatgg acagaaacca agtgggccaa cgtcaatcga attacctttc
    25321 aggatgaatt ttcatccttc aattcaggag tcgcaaaatt aagaaaagga caaacagcga
    25381 ccatcaaagc aaaaattgac tattcaggag acttagcacc tatactacaa tcagctgtta
    25441 catttgagaa tgttgatccc gctttgtcga ttggctatga cgagaacact ttgactatcc
    25501 aacacaagca agcgatattt accttcaccg ttacattaaa tcaggacttg ttaaaaccag
    25561 cgctttttac tgtcaaggta tcagatggac taccgaacga tcatcatcat ttaacgccgt
    25621 atagtcagcg gcagacaatt gagcaagatt cagctatcga ctcaggagga gatcttgttg
    25681 aagaaccaac agataaacca gaaaatgaaa ataagccaga agtaccgcct acagaaaatc
    25741 cagacggaga acagaaaccg gaaatagaac ctggagaaga acccgataca gaaactcaac
    25801 cagagccaga caatgaatca aaacctgaaa taacccctgg agaaaaacca gatgtagacc
    25861 cagaagaaaa accagatgtg actccagaac cagatacgga ttctggaaac caaacagtac
    25921 cggaaacaaa tccagacaca gataatgaaa ctgaaaatcc agaaaaacca gaggtagccc
    25981 cagaagaaaa accagatgta actccagaac cagatacgga ttctggaaac caaacagtac
    26041 cggaaacaaa tccagacaca gataatgaaa ctgaaaatcc agaaaaacca gaggtagatc
    26101 cagaagaaaa accagatgtg actccagaac cagatacgga cgcaagagac caaggaatac
    26161 cagaaaaaat aaacaaaaaa acaattcaag aggatggaaa aaaagagagt aaaaaatcaa
    26221 atctagcaat tctaaaaata aatgaagagc agctgaataa aaaatcacga atatttgata
    26281 gcgcccaatc agctgaaacc ttaaaaagta gcaaggatac aacctttgct gtcctgaaac
    26341 gaaaaataaa cagctaccaa aatccggaga gtcacaaaac aaagttatac tgtggagcgg
    26401 aatcattcta ttaagtatag caacaatgct ttctgcaaaa agatttaaac aaaacagatc
    26461 tctctaacat ttgaataatg tctgtgaacg catttttcaa ataaaaagaa atatccagaa
    26521 aatgacccca aaataccaga ttgaaatctg atatttgggg tcgttcatac tttatctttc
    26581 ttcatattta ttttaaggga tatctgtttc ttttggaaga tggttcggga tctttttcac
    26641 tttcaataca tctaaaaaga aggtaaagat cggaatgccg acaatcaagc cccaaacgcc
    26701 aaagaaccgt tcgctaacaa gtaagaccac aaatgtataa aaaatcggca gttctgtttt
    26761 gctggacatc aacttcggat tcagcacata agactcaatt agatggacaa tcaaaatcgt
    26821 aatcaggata taaacaacat ctcggatgcc tccttgggaa taagctatga aagatagagg
    26881 aatacaagaa atgataacac ctgctactgg gatcagactt aaaatgaaaa tcatgatcgc
    26941 taaactcagc agctgatgaa agccaaatac agccaaggcg attgtagtga gcaacgtatt
    27001 taaaagagcg acaacaaatt gagcttctaa taccaaacca aatgtattga caaacttatc
    27061 ggcaaaatag taaatatctt gaaagaacca agaaaattca ctttttaaaa acaatcttga
    27121 gaatacaatt gtttttttct tttcaatcat aaaaaagaaa cttaagatga atgacatagc
    27181 aaacgccact gccatttttc ctatatcctg taaatagcca agcgcaatcg aagcgccatt
    27241 ttgaagctgt tcaaaaaaat cgtttcgctc aatataagta tggatatatt gtaaaacagg
    27301 atctgcatct tttggctgat gctcgtaaaa attaataacg gactggatca tgtcaaatgt
    27361 ttgatgaata agcatcggga tatactttgt gaatgccaga tagataaggt aaacgatcag
    27421 tgtataaatc atgatagcta aaacacctgt agggattcgg acaaatcgct gaatgatttg
    27481 aacaagatga atcatcaaat aagtaaagat aaatgtgagc aaaatggttg taatcatact
    27541 tctaactaag aaaagaacaa aaacgacaaa taataaaaca gtgagacggc gtattttttc
    27601 attcgccaaa aaacgctgat aaacggtcaa atcgacaacc tccaaataac aaaaaataaa
    27661 cacgttattc attatatgat ggaatatgaa aataagaaag agcaaaaaga aaaaccgcta
    27721 aatgacgtta tcttatgagt tggttttcct cataaaatcg ttcatctagc agtttcagcc
    27781 ctttttctgg tcttgatgaa aattatctag catttttcgg gtcagatgtt gcagtgtatc
    27841 caattcttcc tgttcaagtg gaagataaga cttgatcttt tgtggaatac cttctgcttg
    27901 tttttgcaac gcagcacctt gagcagtcag cgtaacattt acgattcttt catcacccgt
    27961 ttcacgctga cgattaatat aatttttttc tgctaacttt tttagtaagg gagtcagcgt
    28021 accagaatcc agacacaaat catttcctag ctctttcact gaagtctttt tcttttccca
    28081 taaaactaac atcacaagat actgggtata ggtaagattc agcggcttga ggaggggagt
    28141 gtagtgtcta atgatttctt tagaggcggc atataaagga aaacatactt gattaactaa
    28201 atatagatct tccatttttc cacctccgct gttttactat agtgtatcat agcggattta
    28261 cacaaaaaag tctattcact aactgctttc agagtaactt ctatatttcc agctgtagct
    28321 tttgaatacg gacacacttt atgcgctgcc tctaataatt cttgcgtttc ttccagagaa
    28381 agaccttcga tagatccttc aatctctaca cctaagacaa agctcgtttc actttctgaa
    28441 taaagggaaa cttgtgcact gacagtagaa gccccagaga tatttttttg ctgtttgatc
    28501 aattctaatg cactgttaaa acatgcactg aaaccagctg caaacaattg ttcagggttg
    28561 gttgcatttt cgacgcgttt accaggagct gcaatattca attcgaatgt acgatcggga
    28621 ttatgcactt ctccagagcg tccgcctgtg ttgatcattt tcgtagaata catttttttc
    28681 ataaaattac cacctttaat tatattttat acaattgaat tttacacaat ataattgtgg
    28741 aaagcaaaga aatggattgg cataagataa ataagagaaa gcacatgaaa cagacgcgct
    28801 ttctcgaata gcaaacatat acaaaaaata tcagagacaa aaaataatct catcataaac
    28861 attacatata tttctcaaaa agttgttttc tttcttcaaa aattacttca cgatggacct
    28921 gatgaagcat ccataaataa ccaaaaggat ctctgaacat tgagttagtc acaccaaagt
    28981 ccatcatttc tgtcatttct tgaatctcta cacagccatt tcgtaatgct ttattatgtg
    29041 tgtcctcgat atcagagacg atgatattga accagatcgt atttggatgt tcagcagtag
    29101 gagcagtcaa accaagagac gtgttttcat ccagcatatg gaatctcgta ccatacaagg
    29161 taaaaatgac ttcattattg cctctagggt aatctgttgc ctcaatcagt tgtatttcat
    29221 caaagattgt ttgatacagt tctagtgctt tcaaactatc atttaataca aaatcgattt
    29281 ccgttccttt atgcataaag atctcctctc cttttcagtc gaacagttac tagattcttt
    29341 tattatacca gctaaagaaa acgcattcaa aaaaatagcg gatttactta ccaactcatt
    29401 cgattggatg ataagtaaat ccgcgtccca ttacttctgc tacgctgctg acaatgacaa
    29461 aggcacttgg atcgatttct tctatcaatg gtttcattcg ggaaaattca tgatcagtca
    29521 caacgatcaa taaaacctct tttgactttc gattataccc gccttttgcc tctagcaggg
    29581 taaggccacg tccaatctca gcacttaagc gaaggcggat gtcttccaaa taatgttcac
    29641 tcatgaccat aacagatttc tttcgattga tacctgtttc gatataagtc atgacaattg
    29701 aagtgattgc aatagataaa atagcataaa gaaactcttc tattccaaaa ataaacagat
    29761 taagagaaac aacgaatgcg tctgtaaaaa ataagccaat cgaagtattc aagtggaaat
    29821 attttttaaa aatgagggga gggatcgtcg taccgccgct agaagagttg tttttatata
    29881 aaatcgcaac tcctaaagca aaaatcgcac ttccaaaaat gacagacaac aaccgatctg
    29941 aagtaatcat tgtttctgga actattgcaa tgattaaagg aaaaaccaag cttccgaaaa
    30001 gtactttaaa aaagggtttt ttacctaaaa atagaagagc tagtaccaac ataacgatat
    30061 tcaacactaa aataactata gctcggtcaa agcctaaagc agcttccagt aatattccta
    30121 gaccgctgac acctccagca gcaatatgat gaggccctaa aaacatattg atagcgactc
    30181 ctaatatgaa gagggcaaaa ataatcttaa tgtatgtcca tataaattgt ctcgtttctt
    30241 tcatttattc acttccttaa ttcattaata atactcttat cttattataa cttacttttc
    30301 accttaagtt aactttaatt aataaaaaaa ttaggctagt ctaaattatt atgtttcatt
    30361 cttctagaat atacttctac gccaaaaact gttaaaaaac ttttacttta gaaaattgga
    30421 gaaattgatc gcttaagata aattcaggac actaaatagt acaggaagta gactaaaact
    30481 tttaaaagtt ttaagtctat ctatttggca agtttaaaaa ataaaaattc ggtatcaaaa
    30541 aactgttacc gataacattt ttgaaagcgt tgtcttttgc ttctctatca cttatagtga
    30601 tgacgtcata ttaaaacaca aggaggaaat caatggatac agctgcaatt tatcatcgac
    30661 cggaaagtga atatgcattt ctatatacga atacaagatt tcgtattcgg cttcgtacta
    30721 ggaaaaatga tatcaaaaaa gtatatgtgc tatgtggaga tccatatacc ataacaactg
    30781 aaaaatggta tcaaaaacaa cgaccaatga aaaaatgtct aagtaccaat gttcatgatt
    30841 attgggaaat tgaagtgacg agcgaaacaa gtcgcttaca gtatgcgttc catgttgttg
    30901 gggaagataa cacggactgt ttttacggtg atcaaggaat ttttccttat cgagaaaatg
    30961 tgattactga accaaatttt tattttcgaa taccttattt tcatcaaatc gatcgattca
    31021 ctattccaga atgggtaaaa gaaacagtat ggtatcaaat ttttcccgaa agatttgcaa
    31081 acggggacaa agcaaatgac cccgaacaca ctttaccttg gggaagtaaa gatccagacc
    31141 gagaagactt tttcggggga gatttgcaag gtgtgatgga tcatttggat tacttgacgg
    31201 accttggcat caatggcatc tatttttgtc ccatatttaa agccacatcc aatcataaat
    31261 acgatacgat tgattattat gaggtggatc ccgcttttgg cgataaaaaa cttttaaaaa
    31321 acttgattga tgaagcacat aaaagaggga tacgtatcat gttcgatgct gtattcaatc
    31381 atatgggtgt ccattcacca cagtggcaag acgttctcaa aaacggagaa aaatcgatct
    31441 ataaagactg gttccacatc cgttttttcc cagtagattc ttatcagatg actgacttac
    31501 cagaaactgc tgaaaatatc ccatatgata cttttgcttt tactccattc atgccgaaac
    31561 taaatacagc aaatccagaa gtgcaaaaat atttgctgga tatcgcaact tattggataa
    31621 aagaattcga tattgatgga tggcgtcttg atgttgctaa tgaagtcgat catcattttt
    31681 ggaaaaaatt cagagaagca gttacagaaa tcaaaccaga catctatatc cttggagaga
    31741 tttggcattc ctctcaagct tggctgcaag gggatgaatt ccatgcagtg atgaattatg
    31801 catttacaga ttcgattaaa gattattttg caaaaaagaa aatcacagct tcacaaatgg
    31861 tcagtggaat gaatcatcag caaatgcttt acagagatca ggtgaacgaa ggaacattca
    31921 acttattaga ttctcatgat actgccagga tcttgaccct ttgccaaggt aacaaagaat
    31981 tgatgaagtc tgtgatggcc tttatgtttc ttcaaaaagg gtctccttgt atctattacg
    32041 ggacagaaat agggatgact ggtgaagatg acccggattg ccgcaaatgt atgatatggg
    32101 agaaggagga acaagatcta gagctattcg gttttataaa agaacttgtt tctctaagga
    32161 aacagttgtc taagattatt tctgaaggtt ctactcagtg gctaatagta aatgatcgtg
    32221 aagataagct ctatttcaca cggaaactag agggacagat catctatgtt tactttaatc
    32281 agtcaaaaga accttgggta gtagaacagg aaaatgaggt gattcttagt caaaattgtc
    32341 agttgttaga agacgggaaa gcagagatac gacaatacgg atttttgatc atgtgttgaa
    32401 aactgttacc ggtaacaaca agaaagcgtt tgcaaatgaa gatttgtgcc cattataata
    32461 agggtgtaac agcacgttga atacaaagga ggaaatgaag atgaaaaaaa gaagtgtgaa
    32521 acagttgggt ttagggttaa tctctttagg aatcttaggc ggattagcgg cttgtggcaa
    32581 tggtaactct tcagcagaag gggaagccga tgaaggaaaa acgttaacag tttccgttga
    32641 ttctggatat aaagattata taaacgaaat aaaaaacact ttcgaaaaag aaaacgatgt
    32701 gaaaatcaag ctagtagaaa aggacatgtt cgatcagttg gaatcattag cgttagatgg
    32761 gcctgctgga aagggacctg acgttatgat ggcagcatat gaccggatcg gtgcgttagg
    32821 acagcaagga catctggcgg aagtaaaact gggaaatgaa gcagcttacg atgaaacaga
    32881 caaagcccaa gtgacttatg atggaaaaat ctacggagaa cctgcagtaa tcgagaccct
    32941 tgttttgtac tataacaaag atttagtcga tacagcacca tcaacgttta aagatttgga
    33001 gaatctatcc aaagacagtc gttttgcttt tgagtcagaa gcaggaaaaa atacaggatt
    33061 tttagctaaa tggactgact tttattattc ctatggttta attgcaggtt acggtggcta
    33121 tgtatttggt gatgatggca caaatccttc agatatcggt ttgaataatg caggtgctgt
    33181 agaaggaatc tcttatgcaa cagattggtt caaaaatgtt tggccaaagg gaatgcaaga
    33241 cataaaaagt gcaggagact tcgccagcca gcaattcatg tccaataaaa ctgcagcaat
    33301 cattgacggt ccatggcaag cgcaaacata caaagaaaac aatatcaatt atggtgtagc
    33361 caaaattcct actctaaata atggacagcc ttatcaaccg tttggcggag gaaaaggatg
    33421 ggtagtcagc aattatgcta aaaacaaaga cctctctcaa aaatggcttg attatgtaac
    33481 gaatcaggaa aatcaagaaa aattctttga aatggtaaat gaaatccctg caaaccaaca
    33541 agctagggaa acagcaaagg ctaaaaacga tgaattaaca acagctgtga ttgaacaata
    33601 tgaaacagct caagcgatgc caaacatccc agaaatgggc gaagtttgga caggtgcaga
    33661 aaacttgatg ttcgatgcag catcaggttc aaaaacacca aaagaatccg cagatgaagc
    33721 agtaaaaaca atcagtgaag ccatagaaca aaaatactga ttaaaatgat aaccgtccat
    33781 ttttataaaa aatggaacag gtgcttcaga taaaagtggc aagagcgaga tggaaaatta
    33841 tcttgctctt gttgccatta tcttaaaagc agtttgcggt ttagcaagtt tagagggggc
    33901 attcagatgc agcaagataa aacaagcaat atcaacgaaa aaaaaatcac gctttgttca
    33961 cttattccag ggatggggca gtttgtaaat ggccaagctt ttaaaggtat cgtttttttc
    34021 gccatattcg tcctattcat tggtcagatg cttctgggcg gatttcatgc attggtagga
    34081 ttggttactt tgggaagtat accaatggaa gatcattcat tatttatttt gattgaaggc
    34141 actttgcaat tcatcattac aatcattttc ttgatttttt acggtttgaa tcttttagac
    34201 gcttatcgag tagcgaagat gcgtcaagag ggcaaaaaaa tcaatcggac gatgaaggaa
    34261 gtcatacata atataggtga tgaaggtttt ccttatctat tgacacttcc cgcttatctt
    34321 ctcatgattt ttacgatcat tttcccagtc ctagttacat tgttcactgc atttactaat
    34381 tatgacttca atcatattcc accagccagt ttaattgatt gggtaggggc taaaaacttt
    34441 tttagtatct tctttttaag ctcatatcgt aatacttttt ttgcagtctt ttcgtggacc
    34501 gtgatttgga ctttatgtgc aacaactttg caaatcaccc ttggtattct cacagcggtt
    34561 gttgctcacc agaaatttat taaattcaaa cgtattttcg gtatcatttt cttattacca
    34621 tgggcggtcc cagcttttat tactatcatg agtttttcga atatattcaa cgatagcgta
    34681 ggtgccatca atactcaagt gattcctttc ataaaccagc ttccttttgt agatatcagt
    34741 gcaatctctt ggaaaacgga cccgaactgg acgaaagtag caattatctt agtgcagggc
    34801 tggttaggat ttccctatat ctatgtgatg gttacaggaa tcttacaatc gatttcagaa
    34861 gacttatatg aagcagcaaa aatcgacgga gcaaatgcat ggcagcgctt ttcaaacatc
    34921 acgcttcctg ctgtcttcct agtggcagcg ccaacattta ttacacagta tacggggaat
    34981 ttcaataatt tctccatgat ctatctgttt aacaatggcg gtcccggaag cgtaggcgga
    35041 ggagctggtt ctactgatat tcttatttcc tggatctata aacttacgac tggaacttct
    35101 ccgcagtatt ctatggcttc agcaatcacg ttgattatct ccgtcatcgt tatctgtgtg
    35161 tcattgctgg tatttaaaaa gacaaatgcg ttcaatatgg gggattaaca atgaaaaaat
    35221 ttcattcgag tgctcgattc caaaaacgac tttctcactt ttttacttac ttttttcttt
    35281 taatactgtc agtcattatc atctatccgc ttttgatcac agcaagtact gccttcaagt
    35341 caggaaatat tgcagctttt agtttagatc tttcaagtga ctggacttta ggaaacttta
    35401 ctcggctatt cagtgaaaca ctttacggga cttggtataa aaatacattg atcatttctg
    35461 tcctaacaat gatcgtacaa gtgactgtag taactttggc gggctatact tatagtcgct
    35521 atcgttttat cggccgcaaa tcaagtttga tgttcttttt agtgattcag atggtaccga
    35581 ctatggcagc attgactgcc ttttatgtca tggctttctt attagaagcg ctcgataagt
    35641 actggttctt gacaatgatc tatataggcg gtggaattcc aatgaatact tggctgatga
    35701 aaggatactt tgacactgta ccaatagatt tagatgaatc tgctaaactt gatggggcag
    35761 ggcatttcag gatttttttc cagattgtat taccgcttgt caaaccgatg ctcgccgttc
    35821 aagcattatg ggcttttatg ggaccttttg gggatttcat gttagctaag ttcctgcttc
    35881 gaacacctga aaatcagact gttgctgtcg gcttacaaac atttatttct gatgtgacaa
    35941 accaaagagt ctctcttttt gctgctgggg caattttgat tgcactaccg atttgtctat
    36001 tattcttctt tttacaaaag aactttgtta ccggcctgac atctggcgga acaaaaggat
    36061 aggagcagag tatcatgcaa acatttccgt taaactattt ttccgcatta cgtacgccaa
    36121 ctcaagtgtt tgcgggacgc aaactattat catggcctaa atttttcttg atatttgtat
    36181 ttttagtttc cttgatggtc atgcctgtga ctctttttta tgccaatcag atccaagcga
    36241 ttccattaga acaatttcta tccgttcatt cgctgatcga tgaacaagga acccaaaaat
    36301 tttctgaact tgaattatct gaaactgggt tacaagcatc gcaacaaacg atagctgtga
    36361 cccctgaaat tttggtaggt gtgtctttat ctgagaaaca acaatccgat catggaactt
    36421 ttattgattt tgagaaggaa caatgggtga tccaacaaaa ggataaatct ggtatacgcc
    36481 gctatacgat gaattatagc ccatctttcc aaccagattc tgtacgtacg cccgaagatt
    36541 tccaacgatt tttagaaaga gaattttatg ccagtaatcg tccaacaatc attttatctt
    36601 atagtttaag tcttggtctt gtcctatttg tcatgacgag tctcatttta ttcggggctt
    36661 cctttttctt gtggatgaca agaaaaagcc aactttcatc cattcataca ttcaaagaga
    36721 gtgcaaattt gatgctgaat gttatgggaa taggttccat ggcagcagca gttgtagggt
    36781 ttatccactt tgactttatc ttgatgctaa gtgtccaaac aacgataact gtcttgctgc
    36841 ttttatgggt ttttgtcaaa acaagattca aagataagcg tgtcgaatga caagtttaag
    36901 cgatttatgc gacaatgaat gtgaaaaaaa tgaaaaataa agtagttttt gaaaaatttc
    36961 tgaaaaaatt aaacttctta gttgattctt ttctttttta gtattaacgt aatagggtag
    37021 tttttttaag gaggaaaatc atgttagaga aaactttata caatcaatta ttttcacgtt
    37081 ctttctcgct ccctgtcgaa gtaaattatt gggacggtac aacgaaacaa tacggagata
    37141 cggacactcc tccccaaatc aaaatcaata tccatgaaga aatcccaatg aaagagatta
    37201 caagtaacgc ttctttggca ctaggagaag cctatatgga tcatcgaatc gagatcgagg
    37261 gaagtatcca agcattgatc aacgatgctt atcagcaagc aaacagcttt ttacgaggaa
    37321 aagattatct aaaatggctg ccaaagaaag aaaaacatac gaaacaaaaa aacaaagaag
    37381 atatccatgc gcattatgac ttaggtaacg acttttataa actttggcta gatccaactt
    37441 tgacttattc ttgtgcttat ttcaatacac ctgaagatac gttggaacaa gcacaaatca
    37501 ataaagtcca tcatatctta gacaaactct ttatcaaaga aggcgaaacg ttgcttgata
    37561 tcggttgtgg ctggggaaca ttgatgttca ctgctaccaa agagtataat gtcaaggcaa
    37621 ctgggatcac actaagtgaa gaacaatacg atttgattac caaaagaata aaagaagaac
    37681 atttagaaga taaatgccgt gtattattaa tggattaccg cgaactaaaa ggcgaaacgt
    37741 ttgatcatat cacaagtgta ggtatgttcg aacatgtagg ttctgaaaat cttgaaggtt
    37801 atttcaaagt ggtaaaagat ttattgaaac caaaaggaac agctttgatc catggaatca
    37861 gccgacaaca aggcggtgcg acaaatgctt ggatcaataa atatattttc cctggcggtt
    37921 atgtccctgg tgttactgaa ttagttgata atattacaaa aaacgatttg caactgattg
    37981 atttggaaag cttacgtcgt gactaccaat tgacattaga acattggaca aagaattttc
    38041 atcaagtcca agatcaagtc acgaaagaaa tgggtgattc cttctatcga atgtgggatc
    38101 tatatttaca agcttgtgca gcttcatttg aatcaagtaa tatcgatgtg attcaatatt
    38161 tgcttgttca acctggaaac aatgacatcc caatgcatcg tgcataattg aggcaaaagt
    38221 actgtttaaa gactatttaa aaagaagcta agttttatga tgctccagaa gtgaactttt
    38281 ttgtctaact tctaggattg tctctaaagc ttagtttctt tttctttata ttttcataat
    38341 aaaagtttgg ttctttaatt tttaaacatg acagaaaatt ttttcttcgt tatacttgta
    38401 atagaatact attttataac aaaggggatc gaatcaatga aaaaaactgt tatttatact
    38461 agtttatttg cagctttgtt tttagctgct tgtcaatcaa ataccaatca aggcacatct
    38521 gggaatacgt cttccagtag cgaacagcgc tcttcacagg tatcggactc ctcaacaaaa
    38581 gcaagcacat cttcgtctag ccagacaaaa agttctagtg aagcaagtac tcagtcagat
    38641 atcaaagtgt ctgcagctcg tgcgatcgaa ttgttccaag ataaataccc agatactgca
    38701 attactagtt tggaattaga tagtgattgg ggatcttact tctacaagat agaaggtgtc
    38761 gatgatcaaa aagaatacga agcaagaatt gatgctcaaa atgaaaaaat ggagacagag
    38821 aatccagaaa ctctagatcg agatgaacaa aatggtcaaa agaaaaaaga agatggtctg
    38881 gatgttgata aattgatcac gattgaggaa gcagcaaaaa tcgccgtcga caaagtagga
    38941 agcggtacgg caacagattg ggatttggat aaagatttag gtactactta ttgggaagtc
    39001 aaagtaaaag acggcaatca aagtacatca gtcaagatca atagccaaac aggcgaagta
    39061 ctgtcaactg aacaagatga ttaagaattt cttcggaaaa caagagttga tttttctttt
    39121 agtcatgata cactagacaa aataacttgt ttgaaggagc gatttacttg agtttagaaa
    39181 cgacctttgc caatcatatc tttgccaatc ctttgatgaa tgcatctggt gtccactgca
    39241 tgactaccca ggaattagat gaactggctc attcagaagc aggagcattt atcactaaga
    39301 gctgtacgat caatgaacga aaaggaaatc ccgaaccacg ctattttgat gttcctttag
    39361 ggagtatcaa ttctatggga cttccaaact taggtttttc ttattatcta gagtatgctc
    39421 ttgcgtatga aaaagtgcag gaaaaccaaa atcaaccgtt atttttttcc attgccggga
    39481 tgagtgtcca ggaaaacttg gaaatgcttg agaaaataga aaaaagtggg tttaatggga
    39541 tcactgaatt aaatttatct tgtcccaatg tgcctggaaa accacaacta gcttacgatt
    39601 ttgaggccac ttatgaaaca ctgaaagaag tattcagcat cttttctaag ccgctaggaa
    39661 tcaaattgcc tccttatttt gattttgctc attttgatca gatggctgat atcttgaatc
    39721 agtttccatt gacctatgtc aatgctatca acagtgtggg caatggtttg tatatcgata
    39781 cagaacaaga agcagtagtc atcaaaccaa aagaagggtt cggcggcatt ggcggagagt
    39841 atatcaagcc gactgctttg gcgaatgttc gcgcttttta tacacgtttg aaaccagaaa
    39901 tccaaatcat tggtacaggt gggattcgga caggacaaga tgcatttgaa catctgctat
    39961 gtggcgcaag catgttacag attggtaccg agcttcataa agaagggccg gaaatttttt
    40021 ctagaatcat aaaagaatta acgcagatta tgtcagaaaa aggatatacg tcaattgacg
    40081 aatttaaagg caaattacgc accatttcat agcaaagaga cgaaggtcat gattgatctt
    40141 cgtctttttt tataaaaaac actcgtctgt tcattcctgt gcaagcgtac tcattgtatg
    40201 ttagacgaac ttgtgggaaa ataacagagg caaaaaggag gataatatga atgatgcaac
    40261 agaattagca aaagagctta aagaaaaaga atttagtttt caagaactag ttacggatat
    40321 acagaaaaaa ataaagaagc aaaatcatga attgaatgcg tttgtcgcgc ttgaaccatt
    40381 cgagagtaat tcccacgagc tattgattcc ccagtcagaa aaagggccat tggctggtat
    40441 cccatttcct ttaaaaatgc tcggtcaaga aaaaaaggga tggctagcta cttcaggatc
    40501 tcgtttattt gaaacacacc gagcttctca tacatctaat tatgtgcggc aagcagaagc
    40561 gataggtcta gttccttttg gacaaaccaa tgcgccagag tttggtttca aaaatattac
    40621 agacccagtc atctatggcc cagcaagaaa cccttggaac cttgaatgta caccgggcgg
    40681 atcaagtgga ggagctgctg ctgcagtttc atcaggaatc gttcctttag ctggtgctag
    40741 tgatggcggt ggttctatta gaatacccgc ttcgttttgc ggattgattg ggctgaaacc
    40801 ttcgcgaggg acgatgccag ttggtccata tgcttggaga ggatggcaag gagctgctat
    40861 tgatttcggc ttgacagttt ctatgagaga cacggaggct ttattttatg ggatgagaag
    40921 tatccattcc ggtgcgccat atcaagtatc gccagttgag tggcaaacac atccaagaaa
    40981 aaaacggttg aagatagctt tttgtgttga ttcaccgatc cactcacaga ttagtgaaga
    41041 ggcagtactt gctgtaaaaa aagctgtaga tttccttgga aaagaagggc atgatttgac
    41101 agagattcct tacccactag atggtcgtaa actgatcacg tcttattatc agatgaatgg
    41161 cgcagaaaca gcagcaatga tccgctcgat tgaaacaggc atccagcgag ctgtcagaaa
    41221 agaagaactt gaacccattt cttggacttt gttccaatat ggtcagaagc tctctgccgc
    41281 tacttacatc gattctctgc atgtatggga tgaagcagca attgtcatgg aaaacctaca
    41341 tcaagaatac gatctattcc tttcaccaac gactgcattt accgccccta aaatcagcga
    41401 agatttgcaa agtgatgcga taagagcaca gatggaacac atcagtgatt gttctgaagt
    41461 agaaggttta gacgttgttt cttccatgtt tgaggagagc ttgaagatca caccttatac
    41521 acagttggct aatctgactg gacaaccagc aatcagcttg cctactcatt tgacaaaaga
    41581 aaacatgcct ctaggaatcc aatttatggc tgccagagga agagaagatt tgctatttca
    41641 aatcggctat ctatttgaag caaatcatca gttccattta ccaaatccat ggaaatagca
    41701 gaaacaagga gaagaagaat gaagaaaaaa agattgtttg ctctaataac tagtgccttt
    41761 tttattttaa gcgcttgcgg tacagctgcc gctaatcagg aagataacag ctggagtaat
    41821 gtagaaaaaa agaaagaatt agtagtagcg acttctggca cactgtttcc cgcatcttat
    41881 tataatgatc aaaatgaatt agttggttat gatgtagatt tggcaaaaga ggtggctaaa
    41941 cggttaaatg tcaaaatctc ctttaaagaa tacaacgtgg atggacaaat cacttctgtt
    42001 tcaaaaagag aatcagattt tgctgcgaac gattttggta tcacaaaaga aagagaaaaa
    42061 aaattctccc tttcagagac tttcaaatat tcatttgaca gtatgatcgt acgaaaaaaa
    42121 gatgattcag gaatccactc acttgaagat cttaaaggga aaaaagcagc tggcgaaccc
    42181 aatactagct atatgcgttt agcggaaaaa cacggagcta aattagtcac atatgacaat
    42241 gccacgaatg atcagtattt aagcgatgta gcaaatggtc gaacagatgt tattctaaat
    42301 gattattatc tgcagaaaat ggccgtatct gctttaccag atatccctgt aaaaatactg
    42361 gagaacgttt atttcaatga aaacgaaagt ggttttttat tgaaagaagg aaatgatgct
    42421 ctgaaaaaga aaatcgatgg cgtattaaaa gagatgaaag aagatgggac gacaaagaaa
    42481 atatctgaaa aatattttca aactgatgtt tcagtcaaac cgaaagaaac gatggctgag
    42541 tcggtgagtg agtgatgtac tttcctctaa ttgatttttc cctcatgtgg acttcacttc
    42601 ctttcgtact gcaaggcttg gtatacacat tagggattgg cttcgtgtcg tttcttttag
    42661 gaaatctggt agggttgctt ttgacagttt taggtctttt ggattggctg cctctgaatg
    42721 tatttattcg tttttattta tcgttcttta gaggcattcc cgcactagtc ctgctgtttc
    42781 tgttatattt tgggttacct tatcaattaa gtgccttaac ggcttcagtc atctgcttta
    42841 cgattaccag cagtgcattt attggtgaaa tctatcgagg atcactagca ggcgtttctt
    42901 caggtcagtg ggacgctggt ttagcttctg gtttttcttt ctttggggta ttgaaatata
    42961 tcgttttgcc gcaagctttt cgaatctcag taccggcact cagtaacgta gctatggatc
    43021 tagtgaaagg tacttcgtta gcagcaacaa tcacagtgcc agaaatattt caaaaagcaa
    43081 agatcatagg cggtcggaca ttcgattatt tttctctcta tattttagtt gcactgattt
    43141 attgggtcat ttgtatcggg atcgaaaaag tgcaacagta tttagaaaaa cgttctatgc
    43201 atcagtcaat ctgaaaaata gaaatggtgc tagcgtggct ggcaccattt ctattttttg
    43261 tttcttgtat attctgccta gtattttaaa accatttcat gtaaaatgta aatcgaaaat
    43321 atgttcggag gtagaaaaca tgaagacccc gctaaccatc gaaatagaat cctcgttata
    43381 ccaatattgc atcgagcaag gcggcttggt tgtagaagaa gtcacgatgc ctgatgacca
    43441 aggaattgta gatacgctta gctgcttgac aaaatttgat ggaagccgag aatggcgatg
    43501 ctatgagctg aaagtgacaa aagcagattt tcgctctaca gccaaactgt catttgttgg
    43561 acattataat tattttgttt taccaagtaa actatatgaa gaagtaaaaa ctgaaatccc
    43621 tacaggaata ggtgttttag tgtatcgtcc gtacacggtt gaagaggaga tgcctgcctc
    43681 tggtacattt ctgattgcga aaaaagcagc aaagaaagag cttgctgtac cggaagaagc
    43741 tttgacaaac cgcttcatgg cttctttatt cagggaagta agaaaagcaa agcaaatgga
    43801 gcgaggcgta aaatattttc caacagatca attgtacaaa gaattgaaaa gacgttcaga
    43861 aaatcaagat ccattttcta acgaacgata ttatgaacgg tttttagagg aaatagctag
    43921 tcaggcaatc aatgagttgc aagaagaagt tatcgcgctt cagcatgatt atgaatattt
    43981 gaggcaacaa cagcagatcc gtcggttgcc tacagagcca ttggagtgaa aaatatgtac
    44041 tatccttatt taagaggaaa acaatttgac ctattagcat taaaagaagc actgtcgcga
    44101 ggattgctct ccaataaaat ccaaccagtg atcgaaccag tacgtgattc cgctacgctt
    44161 aaaaatgtga tcgaattatt tcaaaaaaag caccatccaa tcgctgtgat ccaaaatccc
    44221 caagtaggac aattcaaatt attcgatcag catgtgcaca gttggacagt caaagaaaat
    44281 agctctgtcg tccctgcaca gatcttaacg ccagaaaatc tcagtgaagt actggattca
    44341 cctccagcgt ttcttgtttt cgatggacag cactacccaa aagatacaga ggtgtggaaa
    44401 cagttggcag gagttgattc gaaatttttg ataccagata ctagtcgctt tcgcatctgg
    44461 ctgcccgaaa acaaaattgt gatccgtgac tcttttcaaa cgagaaagca tgttgaaagt
    44521 tatgcagata aaacagatga cttttttagt gatgactatc tttttttcca cgcagacgga
    44581 tatattggat tttctgattt cacgatcgaa ggtagccgtt atttcgataa agggttccct
    44641 agccgagcgc ttgctatcca tctaacgtat attgatgctt acggcaatat acgcgtgaaa
    44701 cattttgtct ctgacagtaa cgactctgct aaagaccaag cattgaagtt tcttgaagca
    44761 ggagataaaa tgaaaaaatg gatcatgcgt caccatcatc aactcttgat tacttcagga
    44821 atgattgaat tattggctct ttaccagcaa caaaaattcc ctggactggg agtgttgaaa
    44881 aagtggtcac ttatgcatca tttggaactt attagtcacc tgctagatca tccaaaagat
    44941 tggcttaaat attattcaaa agttcaggaa ctatatgaag tgatccaatg attagataat
    45001 gtaaatgaaa aaggaataga aaagaggaaa ctggatgtat attcggcaaa caaggaaaga
    45061 agaagtagaa gaagtggtag aaatcattaa tgccgcagcg gatttcattg cttcgcaagg
    45121 ctctcctcaa tggcaaaacg ggcagaaacc aacaaaagaa acgattttga acgatattga
    45181 aagaaaagaa agctatgtat taatagtgga agatcaaatt gctggaacag ctgcattagt
    45241 ctcaagcgtg gatcccgttt acacaaaaat agatggtagt tggaaagaat caactggtcc
    45301 ttatttatcg attcatcgtg tcgctttagc agaaagtact cgaggaaaaa aactagcaaa
    45361 accgttctta gaacatttgt tgacgattgc agccagcaaa aatatccaag atatccgtat
    45421 cgatacttat ccagctaatg aaccgatgga aaagaccatc tattctgctg gattcactta
    45481 tcaagggatg attgaatttc cttttgaaca cggcgaaaga aaagcatatc aaataatcat
    45541 caattgacta taaaatcatc tgagcaaaga taaagacatt aacactactg aaaaaaacaa
    45601 tcatatgata gccaagaggt tgtaacagaa gtggccagct tcaaaaaaca agaaagaatt
    45661 tccgaaaatg cttctcaaat ttttgtggaa ttttagcgta ttttacgaaa tagctgcttt
    45721 ctgaaactcc cttcatcgag aggtcgtgac atagcttttg tcacgacctc tcggcttatc
    45781 ctacgagtat tattcgatac atttatatca ataatccttt ttttatttta tctgcagctt
    45841 cttggaacgc tccatcgttt gacacgacta aaagtgaggg gatagctttc aaacgtttca
    45901 actgtgctaa atcttctaca taaaccgcca gtctggctga aatctgttca gatgaatctc
    45961 cacgtttttt caggcgcgat tgcaatgttt ctttagagat cgtaataaag ataggacgga
    46021 ctaccgtccc gaaatactca tataaatgcc aaaaaccatt tgctgtcaaa acggcgtaac
    46081 aatttcctac tgtcagtttc tttttaattt ctgctttact ggaaccatat ttatgttgag
    46141 catattggtc ccactctgca aactcatttc ccttgatcat ctgattgaat gtattgtcag
    46201 aaacaaaata ataatcctct tgatcttttt ccccaggtct tggtgatcga ttcgtgtaag
    46261 taatgatctt ttgttccggc tgaaaaatag cttctgcgag tgaagttttt ccagaaccag
    46321 aaggaccgat aaatacatag caataattca ttgtcatttc tcctttgatg attgaacaag
    46381 tgaaaaagct ttggaaaata tttccaaagc ttttaaaagt aactttgctt ttttgtatat
    46441 tataccagca agccagtcac aatagcactt aaaaagctga ctaaagtcgc tgttagcaaa
    46501 attttcaatc cgtgttttgc gacaagattt cctttttctt catttaatcc cttcatcgca
    46561 ccagaaatga tcccgataga agagaagttg gcaaatgaaa cgaggaagac agatataatt
    46621 gctgttgtac gctcagtaaa atggaaatta ccatttgcta attctgtcat agcaacaaat
    46681 tcatttgtaa ccagtttagt cgccatgata ctaccggcat ccactgcttc tttccatggg
    46741 attccgctga tgaaggcaag aggggcaaag atgtaaccta ggatctcttg gaaagtgatg
    46801 ccgaatatcc cgtggaagat agcattgatc atggcaatca aagcaacaaa accgataagc
    46861 atagcagcaa ccgtgatcgc cacatggaaa ccatcaagaa tgtattctcc caacatttgg
    46921 aaaaatgtct gttctttgtt ttcttcaatg atcagctcat cttctttttc ttctaataca
    46981 tagggattta caattgaagc cagaatataa ccgccaaata agttcaaaac aagggcagtg
    47041 atcacatatt tagaatcgat cagtgccata taagatccga cgatcgacat agaaactgta
    47101 gacatagccg atacactcat ggtgaacaaa cgtttctcag ataggaaggg taattccttt
    47161 tttatggaaa taaaaacttc cgattgtcct aaaatagcag aagctactcc attataagat
    47221 tccaatttgc ccaacccgtt gattttactt aatcctagac caacagcttt cataaataat
    47281 ggaagaatct tgatatagcg tagaataccg ataatagcag aaataaatac aattggcatc
    47341 aatacggaaa gaaagaaagg tgcacttcct ttatttgcta caccggcaaa aacaaagtca
    47401 acaccttgcc cagcaaaagc aagaagatga tcaaacattt ttgccaatac agaaacaacc
    47461 gctgtaccaa aagttgtacg taataatacg aaaccaagaa caagctgtaa aacgaacatc
    47521 acaattagtg gtttcaattt gattgctttt ttgttactgc tgatcaaaaa agcaagccct
    47581 aatgtgacaa ataaaccaat aatacctaat aaataactca aataatcact cctattccaa
    47641 attccgtttt attttacctg ttttgcaaat aaaatactaa tctttagtga aattttcatt
    47701 acttttttag agtgaaacgc attcattttc cattagaaaa taaagcgaac aaaataaaag
    47761 gtttaaaaag tgtaacgtct tagtaaagtc tataaaaaaa cgaaactatc gattaagcta
    47821 atagtttcgt tttcaacatt tataagtaaa ctttttctat tggtaatata gattttcgga
    47881 agggtagaca ggtgcgcagg taatatcgat tcctagtttt ttcaatgttt gttcatcatt
    47941 tttattgacc atcacagtag agtgggcttg tgctccctca agttcagcta gtttatcata
    48001 agcaacttga gcgattggat tcgttactgc actgattgat aaagcgatca agacttcatt
    48061 gatgcttagt gcatccaaag aggaatgaag tgtctttgat ttcaatcctt gtattgtttc
    48121 aagaactaat ggtgacaata aaggaatgtc atctgcgata tgggctaaat gttttactgc
    48181 atttaagata actgccgctg acgcatccat caatgaactt gtacgcccgg taatgatgac
    48241 ttcatctggt aattcgattg caatcacagc agaaggatct tttgtaggac tttgcgcttg
    48301 aatcttatct gcatagtcat gggcagggac taccacgttt cggtcttcag gacgtaaacc
    48361 gacttcttcc ataatcagtt tgattcgatt aactgcttct tcgtcgatca atcctttttt
    48421 gaagtcgcat tctgtttgga aataacgacg gatgatttct tgtttagagg cttcttggac
    48481 aacggtatca tccacgatcc caaatcctac acgattcaca cccatgtcag taggagattg
    48541 ataaacagat tctttaccag taattttttc aataatacgt ttgattacag gaaatgtctc
    48601 aacatcccga ttatagttca cagctacttt attgtaggca tcaaagtgga aggaatcgat
    48661 catattgaca tcttttagat cgactgtggc tgcttcataa gcaatgttca gcggatgttt
    48721 caacggaaca ttccatactg ggaaagtttc gaacttggag taaccagctg catgtccttt
    48781 ttggctttca tgatacagtt ggttcaagga agtagcgagc tttccacttc ctgggccagg
    48841 agctgtcact acaacgattg gtttagttgt ttcaatatac tcattttttc caaaaccatc
    48901 ttctgagacg attttttcta cgttgactgg atagtcttcg atttctgagt gtttatagac
    48961 cttgatgttt cgtctttcta gtttattgat aaagactttc gtggcaggct gtccactata
    49021 gcgagtgata acgacactgt tgattaataa gccataacca cgtaattcat cgattaaccg
    49081 caagatatcc atatcataag taatcccata atcaccacgg atcttattac gttcaatatc
    49141 tccagcatag acgcaaatca gtatttcagc ttgatctttc aatttttgca gcaatttgat
    49201 tttcgcatct tcttcaaatc ctggaagtac acgtttcgca tgcttgtcgt caactagctt
    49261 cccaccaaat tctaaatata atttgtcata gtggttcact cgttccaaaa tatacgctga
    49321 ctgctcttca atatattttt ctgaatcaaa accaattttt ttcactaggt tccctcctta
    49381 agtactaaag cattttttca tttttttgag gattcgtcaa ctggaagagc gaaattcctc
    49441 aaaaaaacaa agaaaatggt ttaaaccaac ttgtctagat agttattcat tggtatgata
    49501 gtttttgata aggaaggtgc tacatgaaaa aaagacagaa aaagaaaaac gcatataaac
    49561 actatatccg ttcgattttt accggttatg aaagaatgct tgaagatccc gaattggaac
    49621 aattgacgtt tacttatcta aacgaagaaa cgcagctaac tcgtgatgag catcagcgca
    49681 ttcatttcac aacaagagat ctgcctagta aataaaaaat aagataaagg tcatcggatt
    49741 cgattctgtc ctatcagatg gaaagactag ttgatcgaaa aaaaggctgt accaaatttt
    49801 ggtgcagcct gttttatgga gcattgcccg ctctttttta taacaatttt ttacagaaaa
    49861 tggtactatt gaagtattaa taagtgaaaa acagatgagt aagaggaggc aagtagtatg
    49921 aaagagccag atacaaatgc aaattatgag ccagacgaac tagaggagac gaatgcggat
    49981 caggatacag gacaagaatc gtcttctttt tacgatatca aagaaaaagc aagcatgaat
    50041 ctttcccaat tattagaaga cttacaggct tttgaaaaag ctgtccgcga agaagatatc
    50101 cctgagatct accgtttata caatggccga ttgaatgaag aattaaaaag aagctcaaat
    50161 gaaaatcacg agatcgatca attgctgatg cgtaagatcc atgatcgttt tttacaggaa
    50221 tttcctttta tggaacaagt agaaaacatc tcgccaacga tgagctatta caaaatcggc
    50281 acttattacc atgatcggcc cacggtcggt attgatgcaa gtctgccaga aatttttgtt
    50341 ttgcctaaga tcgatgaaga gtgggagaaa tattcccaac cggagtcaac ggactatgac
    50401 aaaaaaatca atgagctaga cgcaaaggtg atcactgctc agacagaaat tgaacgttta
    50461 gatgaacaaa taaaagaaat caatcgacaa atgactgatt tgaacgacaa taaaggattc
    50521 ttgaatcgta aaaaaatcga ggaagaaatt caagaattag agaagaagaa gcaagtacta
    50581 tctaatgaaa aattaggctg gcttccttat attgagacgc ctgaaacaat ccagcagcaa
    50641 aaagaagcat tgaagcaaga agcaagagca gaccagcttc gtgcagccat cgtagaaaaa
    50701 gaacaaaggc aaatcagacg ctatttcggt agcaaagagg gattcggtca agcaatccat
    50761 gaattcttga tgaattatct tggcaatgag aatcctaata atcaatctaa tgaaggaggt
    50821 tccgagtatg aatgaacacg atgaagcaga atggacaaaa aatgaagaac aaacagaaga
    50881 tcatgaagaa acgaacactt cattggaaga acaaacaagt aatcctctgg atgacacaga
    50941 agaaatccct atgctagagg aaacaaaaat acacgaaaaa gaaaaagtaa ctccgacgaa
    51001 tacgaatact gcagaaaaca cccatgctta cgaaataact gaaaatcccg ggtatttaga
    51061 aggaaaagag caagatcatc aagatatcgt cagtttgatt gaaacagcgg aagcagaatt
    51121 agcggattta cgtatgagaa aagatttgat cgaatcagat tttccacaat tattagaatc
    51181 atatgatcgt tttatattga atgaagaacc aatctccacg atcggaaaga caagcctgat
    51241 cgaatacttc acgtatgaat tactgaaacc gttgaatgat attggtctgg aacggtcaaa
    51301 ttcagcttat gacacatgga aaacaagaca tttttcgatc aattatacgt tgaatggaca
    51361 aaacgaatta gtcttttcct ttgtattacc gaccatcgat caacgatacc aagtggaatc
    51421 gatgagtctc ctaaacgtat caccagagac aatggaaatc aatgtccaag atgaccgggt
    51481 gctttctttg atccgacact ggtcagtgga tcgagtattc tctgcagggc agatcacgat
    51541 attcaatcac aaattgaatc aattattagc ccatgcaaga acacttggtt ttaccgttaa
    51601 tcagacatta ctagacaata cgaagccact tcgtttgaat cttcagagcg aatttgaatt
    51661 gacgaatgaa gtattggatg atatttttat cgtggcaatg aaaaatccat cctacgatat
    51721 ggaaaagatc aacgaaacta cttatcaagt acgattagat aaaggacagt ctttaacgat
    51781 aacaacaaac gaaaaagatc aaacagtctt gtcgatctca tctggagact acccacgatc
    51841 tgtcattgat ttctttatca attacgaatt cttggtccca ttaatggtga gaaagtcctg
    51901 attggataag ttggattacc agatgtcatt cagataattc tgttccaaag gacttgcggc
    51961 agttatccag aataattgtc acaagtcttt tctgtatgta ctaaatggac gtgaataact
    52021 tgctgatgaa ggagggattt cattaggaat gtccacaaat aaaatagcac agcttagctt
    52081 attgtctgct gcttgtgtag caggtaggat cgcttttcaa tttattccga atttccagcc
    52141 aatgactgct atttttttat ttatagtact ttacttaagc ttaaaagatg cgttaattgt
    52201 catgagtctt tctattgcga tcagcagttt ttattttggt gttggaccat gggtcatcgg
    52261 ccaatggatc agctatactg ttgttctgag tttgttttca atcgtctgct tgagaaaaac
    52321 agtgcaaagg aatctatggt taaagggagt ctgttttttt ctggcgggca tggtttacgg
    52381 aataggtatg accgtttttg atacgctgtt atatcgtttg cctcaacctt ggatctatta
    52441 ccttcaaggg gtgtcgtttg atttgatgca cagtataggc aatgttgtgt tctttcttgt
    52501 ttttctgcca gtcgtcaaac gtttttacaa tcattcagga ggaaaaaatg aaaaaaataa
    52561 tttatagttt gcttgcaatg agtgtcagta tactcatttt gacaagttgc agtacaacct
    52621 atacacaatc ggcttccaac caaaaggagg aagtaaaaac atcgcaaaaa gcaacaatca
    52681 cgttacaaga aaatggtcaa aacttttcgg aaaaagaagt gttcttcaaa aaaggcgatg
    52741 atttactgag tattttgaaa cgaaattttg aagtcaaaga agataacggc ttcatcactt
    52801 cgcttgaagg gcactcacag gatgagaaaa atcaactcta ttggatgttt actgtggacg
    52861 ggaaaagtgc tactactggt gccaaagaga tcaaattgaa tgatggacaa tcggtcattt
    52921 tcaatttgtc taaactataa gtttcataaa aaactgttaa agggcgaata ttgccataat
    52981 tcagtgagtt cagttgatga aagaaggaaa ataacatgga aaattttaaa aaaagcggaa
    53041 tgttttccgt aattgctgct ctaggggcta atattctagt tgctatcagc aaatttgtcg
    53101 gctatgcaat cagtggcagt gccgccatgc taaacgaaag catccacagt atcgttgatt
    53161 gcagcaatca gattttgctg ttattcggtg ataaacaagc caataaagga cagagcgagt
    53221 tgcatcaatt tggtgaagga cgagcaaaat actttttcag tacaatcgtc gcaatgatgc
    53281 ttttcttcgg cggtggggca cttggggtga tggaagcttt tgaaaagttg acgcatccat
    53341 cccatgaagt gggtaatccg atcattgtta tagcaatact gttatttggt ttggtaatcg
    53401 aaggaagttc gttacgcgtg gcaatgaaag aaatcaaaga attgaatact gaaaaacttt
    53461 ccacgatgcg ctttttgcgc gaaagtcgac acagtgaaat actgattatt tttacggaag
    53521 acttgtgtgc tgtaatcggt ttggtcttgg ctttagcagg aacaatattg acttatgcaa
    53581 ccgggattgc tgcatttgat gcgatcagcg gattgctgat cggtttcttg ctgatgggag
    53641 ccgccatttt cctagcaaaa gaattttata gtctgatcat cggtgaaagc gtgacagcaa
    53701 gcgatttatc aaaaatcaag ttagcttttg aacgtcctga gatcagtcgg ctgatcgata
    53761 taaaaacagt tcatttaagt ccaacggaga ttttagttgc agcaaaagca gatatcgttg
    53821 gtaacaaaga gaatgaagct tactcggtca tcaatgatat tgaaaaaaat atgcgtcagt
    53881 ctcttcctga caagaagatg tatatataca ttgaaacaga taaatatgac ccaaattatt
    53941 ctcgtaaata aaacgtttat tcatgaattg aagcaaaaat gagaaaaata taatcttgtt
    54001 tttaaataaa acggctacaa tttagcgaat ttatgttaca atgagtccgc tgtttatttg
    54061 ttgtaattaa aggagatatt ttaatgaaca aaaagaaaag tgcgccatgg cttcaagctt
    54121 tgcatgcagt gatgccactt tgtataagct atataccagt aggattagct tgcggagtat
    54181 tgttgcaaaa agttggattt gatcctctct tatcaggact gttatcgatt ctggtctttt
    54241 ccggtggcgc gcagttttta gttgcatcta tgcttacgac gcaagcatca tttgcaacga
    54301 cattattgat ggttttcttt ttagaattac gctatacatt attaggagca agtcttgccg
    54361 gttttatgaa aaaagaaaag cggacgtttt tggctgtctt ttctcaatca ctgaatgatg
    54421 aaaactatgc ggtgaactac ttaaagtttt caactgaccc ttcctggaat aaaagaaagg
    54481 ctttatatgt caattggttc tcaatgactg catgggccgg tagcaatatg atcggtaatt
    54541 ttttcggctc ggtgattcga gtagatgctg accttgtcca ttttgctttg acggccatgt
    54601 tcattttcat gtttatcatg cagatgaaaa gcgcactact gatctttaca ggtttattct
    54661 caggcgtatt aggggtcgta ttcatggtat tattccaaaa tactttcgga ttgattgcag
    54721 caacagtcat tgcttcattt gccggattta tgctggagaa ggcattcaaa aaagaaaaag
    54781 ctaagaaact aagagaccgc ggtaaagatg tcaatgagcc gctcttcaac ttcccggaac
    54841 aggaggccaa tcaccatgac taaactatat ttgctacttt tagttgcttg tctgttcatc
    54901 gtggcatata tcccgcgctt gttcccgatg ctttatttta ctcatcgaaa agtgccatcc
    54961 tggttcagtg actggatgaa atatgtaccg gtggcattat ttgcggcgtt agcttttaaa
    55021 gatgttttca ttactcatga acatctggat attgcttgga atatcaaaat agctgcaatg
    55081 attctagtag caggcgtggc ttacaaaaca cgttcgatgg cgttgtcagt tttgacagga
    55141 cttgcgtctg tctttttgct gtctatgctt taaactgttt tattttatta aaaacagaga
    55201 ttgcgacata agttgttcaa actgatctat ccgaactgca tttgcaacag tcaattctgg
    55261 atgcaagttt attcgtaggg ataaaaaaga ttagtgttgg cttatgatgc aagctctttt
    55321 ttattttagg aattagagag ggatttgtcc ttctatgatt ttttgctata atagggaaga
    55381 tgtttatttt atgaaagaat agttgaggga atttaaatga ataaaaaatt gatgcaagga
    55441 acattttggc taacctttgc taatcttcta tgtaaagttt taggggtagt ctatttgatt
    55501 ccctggctaa gtatgatggg gaacaatcaa gatggtatgc ttgctacgac attgtataat
    55561 gttggctatc ttccttatgg attgttcctg atgcttggta cagtcggatt tccaaatgcg
    55621 attgcaaaaa aagtagctgt agccacaaaa gaaggagata acgctgcttg tcggctgatt
    55681 tttagaagta cgatcaatat catgtttgtc atcggtatcg cctctgctgc actgatgtat
    55741 ttatttgctc ctttactagc cggaatcagt ccgattgcta acgttaataa tgggatacta
    55801 gctatcagaa gtttatgccc atctttgatt gctatcccaa ttcttagtgc aatgagagga
    55861 tatttccaag gaaaaaatga tctgcggcct tatggaactt ctttgattat cgaacaggct
    55921 gtgcgagtga tcgttatctt ggctggtact tattacttgc gcgtattgac tgacggaacc
    55981 atattagaag ctgtattgat cagtacagtc gcttctttct tcggtgggtt agctgcgatt
    56041 atccatatgt atatcgtcgg acgcagaaaa gacttcttcg aacttaaaga ttttttgatt
    56101 tccagccgtt atttcgaaag agaaaaccga tctgcctctg tctctatcat tcgggaaaca
    56161 ctaccgttta tttttgtcgg ctcagtcatt actatcgttc aaatgatcga ccaagtaacg
    56221 atgaaaccac tgcttcactt tttccgtcca gagatcgcag atcagcaact ggaattctta
    56281 ttcagccgtg cttctgtcaa tccaaataaa ttgacattga tcctgatctc catggtagga
    56341 acagtagcta taagcagctt gccaatatta agcacgatga agaaaaaaga tcggatacaa
    56401 atcgaaaaaa cagtaggaga tagtttttcg attgcgttat tgattcttct tccttcattg
    56461 actggaatgt ctttattagc tggaccacta tacacattgt tttttggcta tgatcctgaa
    56521 agtgtcggat atttccaaat ggctttgcta gcttctttgt ttttctcttt attcacgatc
    56581 ctatctacga tgcttcaatc tttgaatcac catcgttttg cgatccgatt aactgtagaa
    56641 gcaattatcc tgaaagtcat cttccaagta atcggattag gattagttgg cggatacggg
    56701 atgagcttat caaatggctt agcattcggt attgtctttg ttcgcggcta tcactttatg
    56761 tgcaaagaat accgaatagc acctttagca aagatcagca attttttctt aaaaactttc
    56821 cgctccaccc tgattatgct tgcagtatgt tttgccgttt tctttttgct gaatcagcga
    56881 ttgtcaatgg aatcaaaaag ctatgcaatg atttattgtg tggctgtagg aagtattggc
    56941 ggcttagtat ttttattttc tcaattcgga aaaaatgggt ttcgaatgtt gaaaaatgtt
    57001 aaacatcata gcagaagcaa agaataggtt aactaatcgt tttttgctgt cacttgaaaa
    57061 acggcaactc gtatgattac gcttgtcgtt tttctatttt ccaattttag tttcatatct
    57121 aatcttactt atgatatagt tataaggtct ggaaaaattc tttgaaacga ggaaattaaa
    57181 cacatgaaac ttgcagtagt tacagatagt tcggcatatc tgccggaacg tatcaagaac
    57241 catcccgact tattcgttat tccaatccct ttgattatgg atgggaaaat ttataacgaa
    57301 ggaatcgata tcgaagcgga tgaatattat ggacttttaa aaaacagtaa agattttcct
    57361 actacttcac aacctgtcgt aggggaagtt ttgggtttat atgaggaatt gaaagagaaa
    57421 gggtatgaca cgattttaag tatccatctt tcttcaggga tttctggctt tgtcaacaca
    57481 ttatttgcga tgaaagatga catcagcgga gtaacggtca ttccttatga ctctaagatc
    57541 actagtatgc cgatgggaca catggtagaa gctgccttag acttaaatga tgaaggtcag
    57601 tcccttgatg aaatacttgc acatatcgat cgaatccgag ataataccta cgcttatctg
    57661 attgtagatg atttgaacaa tttagtacga ggaggacgtt tgacaaatgg tgcagcgctg
    57721 attggcagct tattaaaaat caaaccgatc ctgacatttt ctgaagggaa aattgtttta
    57781 ttcgaaaaaa tccgttcaag taaaaaagca tttgctcgag ctgaagaaat tattggtaga
    57841 agaaataacg aaatacaacc gccagtcaaa ctttacgtga tacatgcaaa taatttagaa
    57901 gtagcgattg cggagaaaga gaaattgcag aaaaaatatc caaatgcaga aatcgaaatt
    57961 ggtcatttcg gaccagtcat tggtacacat ttaggtgaaa aagccatcgg cattgccatt
    58021 tcagcgcaat aattcctttt attcaaaaaa cataccaaaa atattccaac atcatcttgg
    58081 actttctaca tgttactaat gagcgtgtaa aagaacgaga tggtgttttt atttctatca
    58141 atgaagctct ttttctttgc aatcctcact tcaatcctct ataatgtcgc atatagttta
    58201 gtaaatgagt aaactactaa tttacttatt tactaaaaat aaaaggatga ggagttaaaa
    58261 taatggaaat accaacaaat ttaaaacata aaccagtaat cgttgtagaa gactatgata
    58321 aagttgatgg aagaaatgca ttaaatacgg atgcaaaagg gctttcactg ggccttgctc
    58381 agtggaatga tcgtggaaaa gtcgatatct caggcaaggt atggcgacat actggagaaa
    58441 aatggtcacg acagtcggaa gaattaccaa tcacacgtat tttagattta gcgatcttag
    58501 ctgcacaagg aagtttatac ttccaagatg cttatcgtta tgaaaaattt tatgatccag
    58561 aaaatccagt cgtagacatc attggattac aagggaaccg aatgacggta gaagtagata
    58621 ccaaaaatcc aaagatcgat gaagacatca ttttgtatta cgatacacta caaaaagacg
    58681 gagaactgat tggggaacga ttccgtattt taaaacgtct tttagatgag ctaggatatt
    58741 aatagacaga gatgatcaaa aggggaagag aagcatggag aatttctcac taacagaaaa
    58801 ccgaaccttt tcacggctag aaaagcaaat gatctggaag aaaccgaaaa gccatcggac
    58861 aagtgcagaa gaatggcgga tcgcctccga aatcaaaggg aattggcaag atcctgaaat
    58921 gaaaatcagt aacgtacttt tggaaggaga tgccgggtcg gggaagacac aattagccaa
    58981 agcactatct gctgatctgc aacttcccta tacaaaagtg acctgttttg cagatatgga
    59041 caaatcagat gttttcggag ccttattacc tgtagtagat tctaataagg aacaagacca
    59101 agaattacta gaagctattt accaaacaga tacacttgaa gctgtactga cactgatcca
    59161 gaaccattac ggcattgatc ctttttctgc taaagaaaaa ttagcagagc tagttcaaag
    59221 gatcgaagct gattatccag atgcaatcca ttacagctat tacccttctg aaatcgttcg
    59281 agcgattgaa aaaggatatt tattagagat tcaagagccg actgtcatcc gagatgcctc
    59341 tgttcttgtg gcacttaact cagcgctcga accaaatggg atgttgaatt taccgacagg
    59401 aatcattcgt cgccatccag attgcgtcat tgtgatcact acaaatcgaa attaccaagg
    59461 aaatcgccca ttaaatgaat ctttaagaga tcggatgcaa catgcggaaa aaatggatct
    59521 tcctgcctta gaagtcatgg cagaacgtgc gatggcgaaa actatgatcc aaaaacaaga
    59581 acttctctta aagatggcag agattatccg tttgttggat gaaactgcaa aagctaacgc
    59641 catcaaaggt gtagcaggaa tgcgttctta tttttattgg gcaaatacct ataagcaagg
    59701 acaagattta ctccagtcga tttatccaaa agttttgtat aaattatcca ctgattcaga
    59761 tgaattggca attcttgaac aagctttgtc tgacagtgga ttgctactgg aacttcagga
    59821 catattgaga aaagaaaaat ggggtcatcc tcaatctgag catacaaaag gaagaaccat
    59881 tagcgccgaa gaagcaaatg aacgaaacat cactgaaaat gctgaagaaa ttctgcgctt
    59941 agatgaaaag aaatcgttgt ctgctgaaga accaaatgag ggagaagaga aacaagaaga
    60001 aacaatagaa aaaaacgaga ttcctcctca aatgcaaaaa gaacgcagta gcgatatcga
    60061 aggaaaaaat caaaaagaac aacaaacagg agatgattct caagaaatgt ctgcttctga
    60121 catggaagca catgataagg aaatcaagaa gcaactgaat aaagaagcgc gacaaatcat
    60181 gaaggaaacg attcatgaaa aagaaggtct catcgttcac cgaccagctt tccaaggaaa
    60241 aacgccggaa gcacgtgagc tacacatgca agtaatgcca atagtagaat cacttagccg
    60301 gcaaatttta gagttactgg ataatgaaca aacagagacg taccaaaaag gaaaatacga
    60361 aggtcagcgg ttcaatgcaa gcaaagtagc atatggtgat ttgagaaatt ttgacaaaaa
    60421 gaacccgcca catgagcaac cttctttagc ggtagctgta cggatcgatg aatctgggtc
    60481 aatgatacgg gatgatcgga tcgaagcggc aaaaaaagca gcgattgcca ttgccgaatt
    60541 ttctaagaaa gtcgatatcc cattgttgat ttacggagat acagcagacc gttcgtcaag
    60601 agaaaagact tctttgtttt cttataaaga atttgaagac ggatttcaat ggttaaatga
    60661 aaaattagtc actatgaaac caaggcaaaa caatcgtgat ggtgctgcac ttcgtttagc
    60721 agcagaaaaa ttaaacagac aatccgcaac aaccaaactg ttgcttaata ttagtgacgg
    60781 tcagccaaaa gcgttgccgg attatacagg caaaaaagca aaagaagata tccagtctgt
    60841 tttgaaagaa tatgaacgtc aaggaatcct atttgtctcc gcagctattg gccaagacaa
    60901 agaagaaatc aagtcgatct acggtgaaag tcgttttgta gatattactg acttgaatga
    60961 atttcccaag caaatgattc aactgattgc ccgctatcta tgataaaata aagctcaacg
    61021 aacgcactta gcagattcgt tgagcttttc gtttctagtt accggtaaca aggatacttc
    61081 taaaatagaa tcggttataa tcaagaggga ccgttaaagg agtgaaacga tatgatacaa
    61141 gaacaaaaat ggtggaaaga agcagtaggc tatcaaatct atcctgctag tttcaaagat
    61201 agcaatggcg atggtcaagg agacatcaat gggatccgtg aaaaacttaa ttatttgaaa
    61261 gatcttggta tcggctttat ctggatcaat ccgatctatc aatctccatt tgtcgataat
    61321 ggttatgacg taagtgacta tcaagatata gaagagagat tcggaacgat ggaagatttt
    61381 gatttattgc taaaagaagc acatgaatta gggatcaaag tgattatgga tcttgtcatc
    61441 aaccatagtt cggatcagca tcaatggttt gaagaatcga aaaaatctaa agaaagcccg
    61501 tatcgcgatt attacatttg ggtcgacggg gtagatggca aagaaccgaa taattggaca
    61561 tcgattttcg gcggttctgc ttgggagtat tctcatgaaa ctggacagta ttatctgcat
    61621 gtttttgcaa aagaacaacc agacttaaat tgggaaagcg agaaattgaa agaagaacta
    61681 ttcaatatga tccgatggtg gttggataaa gggatagatg gatttcgttt agatgcgatt
    61741 tctcatgtaa aaaaagatga atattcagta aaagccacag agaacccttt ctcacccttt
    61801 caaaatgtct caggaatcga agaacatttg accgatttga aacatgtttt tgaagagtac
    61861 gatatcatga ctgtcggaga agcaagtggt gtcactgcag aagaaggacc acaatgggta
    61921 gggaaagacg gttatttcga tatgatattc gaatttgatc atatccatat ctggcagcaa
    61981 gaaaaagaag ggcaattaga tgtccttaaa ttgaaacttg cattaagcgc ttggcaaact
    62041 tcattggatg gtatcggatg gaacgcttta tatatggaaa accatgatgt tcctcgtgcc
    62101 gtttcagtgt ttggagatac tcgtcccgat ttttgggcta tgtctgcaaa agcaatcgct
    62161 atgatgtatt tctttttgca aggtacgcca tttatttatc aaggacagga aatcggaatg
    62221 acgaatatgc cctttgaatc gatcgatcaa gttgatgcag tagattcgaa aagactttat
    62281 aaaaggctgc ttgcggaagg taagacaaga gaagaagcat tggatatcat tcgtgaaaca
    62341 acgagagaca acagcaggac acccatgcaa tggacttcgg aacaatatgc tggtttttct
    62401 acacatgaac cttggctgat cactaatcca aataccaaaa cgatcaatgt agaacaacaa
    62461 gaatatgaac cagagtcggt cctgcaattc tataagaaca tgatccgcat tagacaaacc
    62521 aataaaggtc tgatatacgg ttcttataaa gaatatcttc atgaacatcc acaactttat
    62581 gtctatgaaa gatatttaga agatgaacaa tatcttatta tggtaaactt aacagaatca
    62641 cttgctgact atgaacttcc aaaagaagca gatcagtcct ggacattact cttgtcaaat
    62701 tcctctagcg gagaatttga agctaaaggc atactagcac cttatgaagc tcggttatat
    62761 aaaacaaaca agtaaaactt cctcgttaaa gttcattagt tggactttgc gaggaagttt
    62821 ttcagattgc tctgtcaatt actcatttca ataattcgct ctaggaccac cgatatattt
    62881 aggacgagag cgaagggctg tcacgtgagc ttgtccaagg gttttcaaac gaggtctgac
    62941 aggtacttgg acatgtttga tatgcatacc gattgatgtg tcaccgatat cgataccggc
    63001 ttgtccaact acgtgttcca cttcgacagg atcattgaac tggtcaaaag cagcaacaga
    63061 acaagcacct ccagcatgta gtgcaggaac aacagagaca atttcgaaat tttttgcttc
    63121 tgccactgtt cgttctacta ctaatgctcg gttcaaatgt tcacaacctt ggacagctag
    63181 cgcaatttct ttaggatcca acaactcttt taacgtacgg atgatccatt gaccaacttc
    63241 cgcactggaa ttttttccaa tatgtcctcc aacgacttcg cttgtgctgc atcctaaaac
    63301 aaaaagatca ccttttttca agtgtgcctc agccaatatg tcattaacta tttcagtcaa
    63361 ttggtctttt aattcttttt ctgacaactt cattttctaa aaccttcttt ttcaattaat
    63421 attgcttccg tgcttgaata cgttgaagac ttgcagttat aggaaaggca agtcccattc
    63481 caatcagatt ttggaagatg tttcctggta tagaagccac tccagccggc caatcatata
    63541 aaatccaacc ggcgatacca tagccgatga tcataactaa gcttcctaat aaaagcccta
    63601 atccccacat acgagtagaa gatttgctga aagaaccagc aacatatcct tgtaacccgt
    63661 ggatcactaa tgaaaaaact gcccactgcg gatatcctga aatcaaatcg atcaatagac
    63721 cactggaagc accaacaact aatccacccg ttggaccata aagaaaagca gcggtataga
    63781 tcccggcctc gcataatgtc acaaatccat tcgtagccgg tacagggatc aaaattgtta
    63841 atgaaagggc aactgtcaac gcaatcagca tagcatagat cgttaattgc ttagttttca
    63901 tttctcattc ctcctttttg aataccgcca gaccagacac ttccggtatg atcgttcatc
    63961 agcacgccat tagaaataca atgggcaaca aattttttac tttctgctac tgctttggta
    64021 aaatctgccc ctaacacaag attcgctgtt attgcagaag aaaaggcaca accggccccg
    64081 tttactgttg tagtgtcgat ttttttatga gaaaatacct cataatgatc aattgaatag
    64141 agaagatcca cagcttcatc tccagccatc cttgtgccgc ctttgatcac aatgtttttt
    64201 gttcctgaag cagtgagttc tttagcgaga tggatcattt ctgttaacga agagggaaga
    64261 gcttgaccag aaagtaaagc agcttctgcc aaattaggcg taatcatcgt aacaagtgga
    64321 aaaagttctt cgatgagctg cgaaatatac aattgattga tcacagcttc agtttctttg
    64381 aatgccaaaa cagggtctaa aatgattggg atattttgtt ttgtttttat gaagtctcga
    64441 acaaccatga ttgcttcact tgaattcaat aacccaattt tgataccatc taatgaagtc
    64501 attttatcaa tcgaaactaa ctgtcgttta agcaattcca aagatataga ttccagcata
    64561 aatcgctcat taatatctag tgcccctata gaagtcaagg cgcttagtcc gaatagacca
    64621 aaattctcaa aagtttttaa atctgtttgg attcctccac cagcaaatgg atcagaaccg
    64681 ccaattgtca agattctttt cataacattt tcctccatga ataagagtat aacgaaattt
    64741 tcaaaaaaga aaaacagcca attggcatat ttttatctca tccaatttaa aaaaacaaaa
    64801 agaaaagaaa gaccaaaatg gatctttctt tccttaaata gttaggactt ttgtgatttt
    64861 aattctttct cgatttgaag ccgttgcact ttcattgtag ctgttcgcgg gattgcatca
    64921 aaatcacgga tgatagggac gttcaagcga ggaagttcat ggacttgctc ccaccatcga
    64981 ttccaatcca tttctttatc aggagctaaa gcaataatcg gttgtggaga atgattttta
    65041 tcccttacaa tcactacttc tgccaaaaaa tctaacgaat ctaataaaaa gtcttcaata
    65101 gctaatgtac tattgatcgt ttcgatcaaa tccacttgcc gatctttcaa aaataggtgg
    65161 ccatgcttat ccataaaacc gtaatctccg ctatcccacc aatcgccata aacattttcc
    65221 tggaaccgtg catcttcctt gtaataagtc aaagcccgtc ctttagacag taattgtata
    65281 tgaccatctg tgttttcagg taggacattc ccaactgaat ctgtaatccg agcgcttgtc
    65341 atgtcttcca gtccaacgcc catatctctt gcatcacttg ttttcaaact ctctagtgta
    65401 tgagccttaa gaatcattgg tccgcattca ctttggccat atacttgaag aaataccgca
    65461 tcctgtgcca tcgacgttcg caaaaatgtc ttcattgtct ggttgtttat agcatcaaaa
    65521 gtggagtgat agtatcggat acccgaaaaa gcttctggat gctccttagc agtaaaacgc
    65581 cactgaacaa agttattcgg atgggtctct agtgcaattg gccggtgagc ttccaacata
    65641 tgaacaactt ttgaactttg tgcgtttgct aaaggcatca taggaaatcc catggacatc
    65701 aaagaagaga taccaatatt gaatctggaa tgcactggag agatgtgaaa agcgattaat
    65761 ttcttttccg aaatttttgt gaaaactgtt ttttgccatt tcgtccgcca tcccatagaa
    65821 tgagcagaat gacaaataag tttagggata ccagttgtac cagaagtatg ggtcatataa
    65881 gaaatttcat ttttgtctaa aaatgattga gaaacagaca aagcaggttg ttccattaaa
    65941 taaagaatag ga
//
LOCUS       DADGKS010000009        65794 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.009, whole genome shotgun sequence.
ACCESSION   DADGKS010000009 DADGKS010000000
VERSION     DADGKS010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 65794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65794
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.009"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            476..1339
                     /locus_tag="JXV47_000595"
     CDS             476..1339
                     /locus_tag="JXV47_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAX1486659.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1468..3090)
                     /locus_tag="JXV47_000596"
     CDS             complement(1468..3090)
                     /locus_tag="JXV47_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAX1486660.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3339..3860
                     /locus_tag="JXV47_000597"
     CDS             3339..3860
                     /locus_tag="JXV47_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486661.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="JXV47_000598"
     CDS             complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="JXV47_000598"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HAX1486662.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5941..6759
                     /locus_tag="JXV47_000599"
     CDS             5941..6759
                     /locus_tag="JXV47_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005232914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HAX1486663.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKHHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6862..7059)
                     /locus_tag="JXV47_000600"
     CDS             complement(6862..7059)
                     /locus_tag="JXV47_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486664.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7228..7806
                     /locus_tag="JXV47_000601"
     CDS             7228..7806
                     /locus_tag="JXV47_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAX1486665.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            complement(8851..9354)
                     /locus_tag="JXV47_000602"
     CDS             complement(8851..9354)
                     /locus_tag="JXV47_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAX1486666.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9713..10738
                     /locus_tag="JXV47_000603"
     CDS             9713..10738
                     /locus_tag="JXV47_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAX1486667.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            11061..11939
                     /locus_tag="JXV47_000604"
     CDS             11061..11939
                     /locus_tag="JXV47_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486668.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            12415..12531
                     /locus_tag="JXV47_000605"
     CDS             12415..12531
                     /locus_tag="JXV47_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAX1486669.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13459..13797
                     /locus_tag="JXV47_000606"
     CDS             13459..13797
                     /locus_tag="JXV47_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486670.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            13891..14121
                     /locus_tag="JXV47_000607"
     CDS             13891..14121
                     /locus_tag="JXV47_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486671.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            14521..14892
                     /locus_tag="JXV47_000608"
     CDS             14521..14892
                     /locus_tag="JXV47_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HAX1486672.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(15166..15858)
                     /locus_tag="JXV47_000609"
     CDS             complement(15166..15858)
                     /locus_tag="JXV47_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAX1486673.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(15861..16646)
                     /locus_tag="JXV47_000610"
     CDS             complement(15861..16646)
                     /locus_tag="JXV47_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAX1486674.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            16883..18283
                     /gene="lacG"
                     /locus_tag="JXV47_000611"
     CDS             16883..18283
                     /gene="lacG"
                     /locus_tag="JXV47_000611"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HAX1486675.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            18308..18625
                     /locus_tag="JXV47_000612"
     CDS             18308..18625
                     /locus_tag="JXV47_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAX1486676.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            18638..20311
                     /locus_tag="JXV47_000613"
     CDS             18638..20311
                     /locus_tag="JXV47_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1486677.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            20325..21956
                     /locus_tag="JXV47_000614"
     CDS             20325..21956
                     /locus_tag="JXV47_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-1,4-beta-galactosidase"
                     /protein_id="HAX1486678.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(22447..24012)
                     /gene="guaA"
                     /locus_tag="JXV47_000615"
     CDS             complement(22447..24012)
                     /gene="guaA"
                     /locus_tag="JXV47_000615"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAX1486679.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(24071..24994)
                     /locus_tag="JXV47_000616"
     CDS             complement(24071..24994)
                     /locus_tag="JXV47_000616"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HAX1486680.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            25190..25795
                     /locus_tag="JXV47_000617"
     CDS             25190..25795
                     /locus_tag="JXV47_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAX1486681.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            26103..27119
                     /locus_tag="JXV47_000618"
     CDS             26103..27119
                     /locus_tag="JXV47_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAX1486682.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            27260..28561
                     /locus_tag="JXV47_000619"
     CDS             27260..28561
                     /locus_tag="JXV47_000619"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HAX1486683.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            28607..29269
                     /gene="deoC"
                     /locus_tag="JXV47_000620"
     CDS             28607..29269
                     /gene="deoC"
                     /locus_tag="JXV47_000620"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HAX1486684.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            29290..29688
                     /locus_tag="JXV47_000621"
     CDS             29290..29688
                     /locus_tag="JXV47_000621"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HAX1486685.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            29754..30836
                     /locus_tag="JXV47_000622"
     CDS             29754..30836
                     /locus_tag="JXV47_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HAX1486686.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            31048..32610
                     /locus_tag="JXV47_000623"
     CDS             31048..32610
                     /locus_tag="JXV47_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1486687.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            32603..33736
                     /locus_tag="JXV47_000624"
     CDS             32603..33736
                     /locus_tag="JXV47_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1486688.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            33736..34692
                     /locus_tag="JXV47_000625"
     CDS             33736..34692
                     /locus_tag="JXV47_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1486689.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            34791..35957
                     /gene="deoB"
                     /locus_tag="JXV47_000626"
     CDS             34791..35957
                     /gene="deoB"
                     /locus_tag="JXV47_000626"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HAX1486690.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            35981..36799
                     /locus_tag="JXV47_000627"
     CDS             35981..36799
                     /locus_tag="JXV47_000627"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAX1486691.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            36816..37523
                     /gene="deoD"
                     /locus_tag="JXV47_000628"
     CDS             36816..37523
                     /gene="deoD"
                     /locus_tag="JXV47_000628"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAX1486692.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(37821..38507)
                     /gene="gpmA"
                     /locus_tag="JXV47_000629"
     CDS             complement(37821..38507)
                     /gene="gpmA"
                     /locus_tag="JXV47_000629"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAX1486693.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(38679..39260)
                     /locus_tag="JXV47_000630"
     CDS             complement(38679..39260)
                     /locus_tag="JXV47_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAX1486694.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(39393..40076)
                     /gene="rpiA"
                     /locus_tag="JXV47_000631"
     CDS             complement(39393..40076)
                     /gene="rpiA"
                     /locus_tag="JXV47_000631"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HAX1486695.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            40395..40808
                     /gene="rpsL"
                     /locus_tag="JXV47_000632"
     CDS             40395..40808
                     /gene="rpsL"
                     /locus_tag="JXV47_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007085295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HAX1486696.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            40892..41362
                     /gene="rpsG"
                     /locus_tag="JXV47_000633"
     CDS             40892..41362
                     /gene="rpsG"
                     /locus_tag="JXV47_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HAX1486697.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            41456..43543
                     /gene="fusA"
                     /locus_tag="JXV47_000634"
     CDS             41456..43543
                     /gene="fusA"
                     /locus_tag="JXV47_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAX1486698.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            43715..44902
                     /gene="tuf"
                     /locus_tag="JXV47_000635"
     CDS             43715..44902
                     /gene="tuf"
                     /locus_tag="JXV47_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAX1486699.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            45309..45617
                     /gene="rpsJ"
                     /locus_tag="JXV47_000636"
     CDS             45309..45617
                     /gene="rpsJ"
                     /locus_tag="JXV47_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HAX1486700.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            45648..46277
                     /gene="rplC"
                     /locus_tag="JXV47_000637"
     CDS             45648..46277
                     /gene="rplC"
                     /locus_tag="JXV47_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HAX1486701.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            46305..46928
                     /gene="rplD"
                     /locus_tag="JXV47_000638"
     CDS             46305..46928
                     /gene="rplD"
                     /locus_tag="JXV47_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HAX1486702.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            46928..47218
                     /gene="rplW"
                     /locus_tag="JXV47_000639"
     CDS             46928..47218
                     /gene="rplW"
                     /locus_tag="JXV47_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HAX1486703.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            47257..48090
                     /gene="rplB"
                     /locus_tag="JXV47_000640"
     CDS             47257..48090
                     /gene="rplB"
                     /locus_tag="JXV47_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010747214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HAX1486704.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            48133..48411
                     /gene="rpsS"
                     /locus_tag="JXV47_000641"
     CDS             48133..48411
                     /gene="rpsS"
                     /locus_tag="JXV47_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HAX1486705.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            48434..48781
                     /gene="rplV"
                     /locus_tag="JXV47_000642"
     CDS             48434..48781
                     /gene="rplV"
                     /locus_tag="JXV47_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HAX1486706.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            48795..49451
                     /gene="rpsC"
                     /locus_tag="JXV47_000643"
     CDS             48795..49451
                     /gene="rpsC"
                     /locus_tag="JXV47_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HAX1486707.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            49454..49888
                     /gene="rplP"
                     /locus_tag="JXV47_000644"
     CDS             49454..49888
                     /gene="rplP"
                     /locus_tag="JXV47_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HAX1486708.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            49878..50066
                     /gene="rpmC"
                     /locus_tag="JXV47_000645"
     CDS             49878..50066
                     /gene="rpmC"
                     /locus_tag="JXV47_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HAX1486709.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            50091..50357
                     /gene="rpsQ"
                     /locus_tag="JXV47_000646"
     CDS             50091..50357
                     /gene="rpsQ"
                     /locus_tag="JXV47_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HAX1486710.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            50415..50783
                     /gene="rplN"
                     /locus_tag="JXV47_000647"
     CDS             50415..50783
                     /gene="rplN"
                     /locus_tag="JXV47_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002460061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HAX1486711.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            50820..51128
                     /gene="rplX"
                     /locus_tag="JXV47_000648"
     CDS             50820..51128
                     /gene="rplX"
                     /locus_tag="JXV47_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HAX1486712.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            51156..51695
                     /gene="rplE"
                     /locus_tag="JXV47_000649"
     CDS             51156..51695
                     /gene="rplE"
                     /locus_tag="JXV47_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HAX1486713.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            51714..51899
                     /locus_tag="JXV47_000650"
     CDS             51714..51899
                     /locus_tag="JXV47_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HAX1486714.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            51935..52333
                     /gene="rpsH"
                     /locus_tag="JXV47_000651"
     CDS             51935..52333
                     /gene="rpsH"
                     /locus_tag="JXV47_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HAX1486715.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            52365..52901
                     /gene="rplF"
                     /locus_tag="JXV47_000652"
     CDS             52365..52901
                     /gene="rplF"
                     /locus_tag="JXV47_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HAX1486716.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            53062..53418
                     /gene="rplR"
                     /locus_tag="JXV47_000653"
     CDS             53062..53418
                     /gene="rplR"
                     /locus_tag="JXV47_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HAX1486717.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            53439..53939
                     /gene="rpsE"
                     /locus_tag="JXV47_000654"
     CDS             53439..53939
                     /gene="rpsE"
                     /locus_tag="JXV47_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HAX1486718.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            53954..54133
                     /gene="rpmD"
                     /locus_tag="JXV47_000655"
     CDS             53954..54133
                     /gene="rpmD"
                     /locus_tag="JXV47_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HAX1486719.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            54177..54617
                     /gene="rplO"
                     /locus_tag="JXV47_000656"
     CDS             54177..54617
                     /gene="rplO"
                     /locus_tag="JXV47_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HAX1486720.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            54617..55912
                     /gene="secY"
                     /locus_tag="JXV47_000657"
     CDS             54617..55912
                     /gene="secY"
                     /locus_tag="JXV47_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HAX1486721.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            55974..56621
                     /locus_tag="JXV47_000658"
     CDS             55974..56621
                     /locus_tag="JXV47_000658"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HAX1486722.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            56812..57030
                     /gene="infA"
                     /locus_tag="JXV47_000659"
     CDS             56812..57030
                     /gene="infA"
                     /locus_tag="JXV47_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HAX1486723.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            57063..57179
                     /gene="rpmJ"
                     /locus_tag="JXV47_000660"
     CDS             57063..57179
                     /gene="rpmJ"
                     /locus_tag="JXV47_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HAX1486724.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            57197..57562
                     /gene="rpsM"
                     /locus_tag="JXV47_000661"
     CDS             57197..57562
                     /gene="rpsM"
                     /locus_tag="JXV47_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HAX1486725.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            57590..57979
                     /gene="rpsK"
                     /locus_tag="JXV47_000662"
     CDS             57590..57979
                     /gene="rpsK"
                     /locus_tag="JXV47_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HAX1486726.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            58059..58997
                     /locus_tag="JXV47_000663"
     CDS             58059..58997
                     /locus_tag="JXV47_000663"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HAX1486727.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            59025..59405
                     /gene="rplQ"
                     /locus_tag="JXV47_000664"
     CDS             59025..59405
                     /gene="rplQ"
                     /locus_tag="JXV47_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HAX1486728.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            59677..60516
                     /locus_tag="JXV47_000665"
     CDS             59677..60516
                     /locus_tag="JXV47_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAX1486729.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            60492..61361
                     /locus_tag="JXV47_000666"
     CDS             60492..61361
                     /locus_tag="JXV47_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAX1486730.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            61351..62148
                     /locus_tag="JXV47_000667"
     CDS             61351..62148
                     /locus_tag="JXV47_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAX1486731.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            62351..63097
                     /gene="truA"
                     /locus_tag="JXV47_000668"
     CDS             62351..63097
                     /gene="truA"
                     /locus_tag="JXV47_000668"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAX1486732.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKVRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            63762..63999
                     /locus_tag="JXV47_000669"
                     /pseudo
     CDS             63762..63999
                     /locus_tag="JXV47_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299509.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(64143..64919)
                     /locus_tag="JXV47_000670"
     CDS             complement(64143..64919)
                     /locus_tag="JXV47_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAX1486733.1"
                     /translation="MNIHHIRNATAILDYGGKKFLIDPMLAEKGTLPPFISKGPFPSP
                     RKDQMNPLVDLPMPVEDIINGIDAVIVTHLHLDHWDDIAKEVLPKEIKLFVQDENDAN
                     EIRLYGFKNVEVLREDTVFESIQLVKTKGKHGRGEILNYVGNVCGIVFKHSTEKTLYF
                     TGDTVWYEAVKQTIDQYNPEIIVANAGDNHFLVGESLIMGKDDLYELHKAIPDSTIIA
                     VHMEAVNHWGLSREELKSFNKEKGISEKVLVPEDGDNIFI"
     gene            65042..65449
                     /locus_tag="JXV47_000671"
     CDS             65042..65449
                     /locus_tag="JXV47_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HAX1486734.1"
                     /translation="MLDQTDINIIEELSKNSRITMKELGEKVHLTGPAVSARVTKLEE
                     SGVIENYTVKLNMEKLGFSIHAFLIIITQNLNHKPYLSFIKNHEKFLIRNYKISGGGC
                     YLLECRFTSKKSMNSFLEQLNEYANYKLSIVID"
BASE COUNT        20925 a        11726 c        13856 g        19287 t
ORIGIN      
        1 ccactaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
       61 gagaagctgt tttttgaaat tgttccttgt gactcggagc taaacggcag gctcacaacc
      121 tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
      181 tgaggaacta ttttttccgt ttttttctct aatactcagg tcaaaacgct gatttcacaa
      241 cctctgattc acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttat tttgattaga acttgcgaaa ataaaccggt taaagtgtgt ctagcgcaag
      421 agatttgcta taatagacga taagggtaaa atgtaacgag aaggggttga aaaatgtgta
      481 tcaaattgta acagattctt gttgtgatct gccataccat gtattagcaa aagaaaaagt
      541 tgatttttta tcaatgaatc tccaattgaa tgatcaagag ttagtagatg acctcggaaa
      601 gacattcaat tatgaccgct acatgaatca gctgaaaaat ggtgcgatgc ctacgacatc
      661 acaaatcaat gttggccgat atttagaatt tttccgttct tatgcggaaa aacagattcc
      721 tgttttatat gtggcttttt ccagtggatt aagcggctct tacagtagtg cgcttcaagc
      781 ggttgaattg ctgaaggaag aatatgaaga ccctgagatc tatgtttttg atacaaaagc
      841 tgcaagtatt ggggaagggc ttttagtatt ggaagctgta agattgaaaa aagaaggtaa
      901 aagcatcgaa gaaaccctag agtggctgga aagtaattat ttgaaagtcc attcatgggt
      961 aacagtagac gatctgaaat atctagaacg aggcggtagg atttccaaag caagtgctac
     1021 tcttggcagt ctattgagtg taaagcctat tattacggtg gataaagaag gaaggctgac
     1081 gaatgttgac aaagttcgag gaagaaacaa gtcgatccag acaatcgtca atgagacggt
     1141 aaaaacaatc gttgcaccac ttgatcaaat cgtttatgtg gcttacgctg gggatctaga
     1201 gagcgcggag aaggcaaaac ggcttttgga agagcagata aagatgaaag atgtgaagct
     1261 ttatccctta ggaccaacga tcgccagtca cacaggctat ggctgtatcg cgattttttc
     1321 gatgggaatc agtcgataaa agcagtaact cattctgtaa aaaagcccag aaattgattg
     1381 taacaaaaac agcgactctt aaaagataga tgagcatcct atctcttaga ggtcgctgtt
     1441 tttttatttt ttaagctaaa taggccatta tgcccataac tcgttcaatt gtttttgaat
     1501 atctgcattt tccaaaaatt catcatatgt cgtatcagct cgatcgatca cacctttatc
     1561 cgaaacggca atgatgcggt ttgccaatgt ttggataaat tgatggtcat gtgacgcaaa
     1621 taagattgag ccagtaaatg ccatcaagcc gtcattcaat gctgtgattg attctaagtc
     1681 taaatggttc gttggatcat ctaatacaag tacgttagct ttcgaaagca tcatttttga
     1741 aagcatgcaa cggactttct ctccaccaga taaaacattc actggtttca atacttcttc
     1801 accagaaaac aacattcttc ctaagaagct tcttaagaag gtgttatcat cttcttcttt
     1861 acttgcatat tgacgcaacc agtctaaaat cgttagatca gtatcgaatt ctttcgttgt
     1921 atcctttggt aaataagaat tacttgttgt cacaccccaa cgtactgttc cagtatctgg
     1981 cgtaatttca cccatgataa ctttgaatag cgttgttgtt gttatatcat tttctgcgac
     2041 gaaagcgacc ttgtcttctt tgctcaaatt aaaagatata tcatctaaaa ttttctttcc
     2101 atcaatcgtt acacttacat tttctacctg caataagtcg tttccaatct cacgttcagg
     2161 tttgaatcca acgaatggat aacgtctaga agaaggttgg atatcgtcta aagtaatttt
     2221 ttcaagcatt tttttacgtg aagttgcttg ttttgatttt gatgcattcg cactaaagcg
     2281 ggcaataaat tcttggagtt ctttgatttg ttcttctttt ttggcatttg cgtttgcttg
     2341 aagtttagcc gctagttgac tagattccaa ccaaaaatca taatttccta cataaagttt
     2401 gattttacca aaatctagat ccgccatatg tgtacatact ttgttcaaaa agtgacggtc
     2461 atgggataca acgatcacag tattttcaaa attgatcaaa aattcttcca gccaattgat
     2521 cgattggata tccagaccgt ttgttggttc gtctagcaaa agaacatcag gtttaccaaa
     2581 tagtgtttgt gctaataaca cttttacctt ttgtccacca gttaattcac tcatttgctg
     2641 atggtgcaat tcttcaggga tgttcagacc ttgcagtaaa acagctgctt ctggttcagc
     2701 ttcccatcca ttaagctcag caaattctcc ttctaattca gctgctcgaa taccatcttc
     2761 gtcagtgaaa tcctctttca tgtaaatcgc atctttttct ttcagcactt catacagacg
     2821 cttgtgtccc atgatgactg tttcaagtac agtatagtct tcatagtcgt aatggttctg
     2881 tttcaatacg gccatccgtt catctggtcc catagtaacg gaacctgtgg aaggctgcag
     2941 atcccctgat aacactttaa ggaacgttga tttacctgca ccatttgcac caatcaagcc
     3001 atagcagttt ccgggggtaa atttaatatt cacatcatca aatagtttgc ggtctgaaaa
     3061 gtgcaaactc acatcattta cagtaatcaa tttttttcct cacttttatc attattagtt
     3121 ttgacaagtc ttatagaatt atatagggga aaggtaaaag attcaaggca atcgaacatt
     3181 ctttgtgttt cacgtgaaac agaatgaaaa aaataaaaat aaaagcggag cgaaaatagc
     3241 tactatagga tttattagtt tgcaacagca taatttttga cgttatttat aagagggagt
     3301 actataaaac tgtaaaagaa atgaaagaag gattgaaaat ggatgaaaaa agaaccatcg
     3361 actggggctc attgattttg ggaattttat ttgtacttgt ctcattgtta tcatttcaag
     3421 accctgtcgg aaatttagtt gcaattgtag tagtctttgc gatttttgcc tttattaaag
     3481 ggatatttga actgtttgta cggaacagat taaaagagct aacaggatat aaaggaaaga
     3541 tgcccttaat aatcgggatc atcgatattc tagttggcgt ctttttctta ttcaatattg
     3601 gtgcaggagt cgcagcattg ccttttgttt ttgcagtatg gtttattgct gattcagttt
     3661 tagcgttatt tactgctgac ttggcaagag gagtaagtga aggatattat tggtttacga
     3721 tcatcgtcaa tattttagga attttattag gaattttctt attgtttaat ccaatttctt
     3781 ctgcgttgac attaagcttt ttagttggat tctattttat gttatttggt atcacacata
     3841 tcgtctatgc atttagataa gtaaaatcaa acaaataaaa aagccggctt ccgattacag
     3901 ttttactgtt gtaattggaa gccggctttt ttatcatgga caaatatgca cgaggtgatt
     3961 tttaggtgtc gagacaaatt tatgcaaaaa tgtgagaagc tatatacaca aattttatct
     4021 taatactcga agcatagcgc agttgtcaca acctcttttc atataattca ttcaatactg
     4081 gcaaatcatg gacttcatat ttttctttga atgcttggat ttcttcttca gaatattttc
     4141 ttggatctaa atgcagatct tctactggca atgggcgctt gttattgatc ttcacatcga
     4201 ttactacagg acgatctgat tttgcagctg catcaaaggc aaatcgaagt tgcgagtatt
     4261 ctgtgactgt aaagctattt gccccgagcg cttctccaac tttaccgaaa tctgcatctt
     4321 ctaaaaatac accaaatttc ttttgttccg tatcttcttg ttctgcttcg atgaaaccaa
     4381 aagaatcatt cgaaaagaca acattaataa ttggaagctg atatttgact tgtgtaatga
     4441 tatcttgcat gaccatagca aacccgccat caccacttaa ggtaaatact tgtttttctg
     4501 ggtagcttag ttgtgcggca attcctcctg gcacaccatt acccatagtt gcgaaccatc
     4561 cagatgtcgt atgtttttgt ttaccgttca tattcaataa acgaatagaa tggatagtcg
     4621 tgttaccgac atctgtgacg aaaatcgcat cgtcttcagc aatacgattg atttctttat
     4681 agacagcctc tggacgaatc ggttcttcct ctcgatcttc aaaagatttc aaccaattta
     4741 cccatttttc tttattttct tgatttgcta ggtaccagct atcagcaggg cgagcatccc
     4801 ctaactcgac aagtctttgc aaagctgtgt ttgcatcacc gaggatcgac aaagatgttt
     4861 catggcgtcg tccaaatttt gacgcatcga tatcgatttg gataaattca gcagttggat
     4921 taaaaaatgc acgtccaaat gggaagtcgc taccgacaaa taagatcaga tcggcttctg
     4981 ccaatgcttc atttccgggt ttagtagcga cacgtccagc aaaaccaaga aagttttcat
     5041 aatcatcagg aataattcct tttgctagaa cggaagcgac aacaggaact gaaaaatgtt
     5101 ctgagaattc tttgatttgc ggaaatccgt ttcgcgttcc ttgaccaaca taaagaactg
     5161 gtttttttgc tttttcaaga taaggcaaag cagctagcaa atctttttct tctggtaata
     5221 tcacacttgt tttgtgagtg tgagcggtgg agaaaggttg ttcgtcaatt tcttcaaaac
     5281 caagatcaac agggatagtc acgatagcca cgcctttatg ctcataggcg gctttaatgg
     5341 cttcatctac tacatgcgga agactttgtg gtgtcatgac tgtacgattg tatacgctaa
     5401 catctgcgaa aataggattt tcatttagtt cctggaaaga gttatagttc atggatgtag
     5461 aagcaacttg tcctaagaac gctactagag gcacatggtc catctgtgca tcatacaaac
     5521 cattgatcaa atgtgtcgca ccaggtcctg cagagccgaa gacagcgccg actttccccg
     5581 ttaattttgc atctgcagcg gctgcgagtg cgccgacttc ttcatgacga acttgaatgt
     5641 agttgatttc ggttttttct tgatatagcg catccataat tgaattgaaa gatcctccgg
     5701 gaatgccgta aatatggtcg ataccccagc tttcaagaac ttttaccatt gcgattcctg
     5761 cattgatttt tgacatggtg tttcactcct ttagcaatga tgatacataa attttttgta
     5821 tctagagtat agaacttttt atcgaaaatc ccaactaatt cgtcttttca caaaaatgta
     5881 gtcatgtttt tgggaatatg ctagagtagt acatagatag attcaagaga ggggaatggc
     5941 atggttgaat ggctattgag acttgaacct tggcagcaag cacttgctgg gacagctttt
     6001 acttatttta tgacagctct tggtgccggg ttggtttttt tctttaaaga aatcaaaaaa
     6061 gaagtgctaa acttgatgtt aggatttgct tctggtgtca tgattgctgc aagtttttgg
     6121 tctttgttag atccggctat tacaaaagca gaagaaaatg gagatattgc ttggctagtt
     6181 gtaagtattg ggtttggttt aggcggtgtg tttttatata tggcagataa aacactgccc
     6241 catatgcatt ttggaccaca acatgaagca gaaggattgc ctacccattt aaaacggacg
     6301 atcttgcttg ttttttctat tacattgcat aacattcctg aaggtttagc cgtgggggta
     6361 gcattcggtg cagcagcaac tgcggataat ccgacagccg ctatattagc cgctgtttcg
     6421 gtggcgctag gtattggtat ccaaaacttc ccagaaggag cagctgtatc aatcccgttg
     6481 cgacaagaag gtctgagtcg taaaaaggcc tttgtttacg gacaagcttc tggaatcgtt
     6541 gaaccaattg ctggagtgat tggagcgcta ctagtaacga aagtggagct gctgcttcct
     6601 tatgcacttg cttttgccgc aggagcaatg atttatgtcg tggtggaaga attgatccct
     6661 gaagcacagc agacattgtc cagcaaacat cattttgcag tttttggcgt catgagtgga
     6721 tttatcatta tgatgatttt ggatgtggca ttaggataaa taaaaaaaat atatatgata
     6781 tatcaaatag ggccgcgaac ttatatcgcg accctatttt tttagtaagt tatatcataa
     6841 tgaagtgaat ggtatcatac attaataata gttttttcta tgtgtatttc ctttgatcca
     6901 gcgaacaagc cagatgataa gtgcgattgg gattagaact ttgaccgcaa accataaaag
     6961 cccgcttagg acactgacaa aaagactgat gacgaagcta gctgcaatta gcactaaaag
     7021 aaccatgaag atatttaaga acatattttt ttgacgcata caaaaccctc ctcttgttca
     7081 ttctttacta tagaaaaagt ataacaggga ttgtttaaaa acacctccaa ctgaagactg
     7141 atttttactt catctactta aatgatcaaa caattgcttt ttctctggtt tatcatctaa
     7201 aatagagcgg aaaaggagga gaatatcatg cctaaaaatc gtcttgaagc atttacagat
     7261 gctgtaatcg cgattatcat gactatttta gttttagaac ttcatgaacc taacggagac
     7321 acgtgggagg cgctcgctgc attaggttac cgatttttta tctatattgt cagttttatc
     7381 attttagcga tttattggaa caatcatcat catttatttc aagttgtaca taagataaat
     7441 ggacgggtct tatgggcgaa cagtttcttt gtttttgcgc tttcgctttt tccgtttgca
     7501 acttcatgga tcagtgagta catcaatagc ctggctccag aaatgactta tggttttgtt
     7561 accttgaccg ctaatattgc gtattatatc ttggcaaaag aacttgtcaa agcaaataaa
     7621 ggccacgaga aagcattgaa ggcgatgttg aataattaca agaaatcgta tctatcgatt
     7681 ggtttgaatg tgttaggaat tgtcttaggg tatttagtag cgccagtagc cgtgctgatc
     7741 gcaaacatcg tgattctagc tgcttggatc atcccaagtc gtaccatcga atcacaatat
     7801 cggtaaaatg atccgtgttt aaaatttaag agaaaaatat agaaaaaata aataaacgat
     7861 caaatatccg agtgatacta gtattcaaag agggatgcag atggatcaaa aaagaattca
     7921 tgtaggactg attactagtt ttgtcacgat gcttatttat ttggatcaag gtcatttgac
     7981 ttggacagta gttggtgtcg taggattttt gacattattc acagcaataa aaaaataaac
     8041 atctttatgt aatctgatgt tctatctatt taagaaaagc atgtttacag cagtatgatt
     8101 ctgttgtaaa cgtgttttta tttgtggaaa atttaatttt tagaaaagtg tatcgaaaaa
     8161 tagatagtta gtttttccac agtggataac ttcgtaagag ataaaaataa aaaattagtc
     8221 aaagaagggc gtatagattt cttttgatag gagatataca acagaaatga ataaatatta
     8281 acgtgttttc aaacagtata aaacggtgtg gtttttggaa taaaaaaata acatatctca
     8341 ttttacactt ttgttatttt atacttaaaa aataacgaca cagaaaatac cgtgtctcag
     8401 atttctctac tacttctaaa aactactgtt tttttccttt gaaatgcctt caaaaagtag
     8461 gatcaggcag aatatactgg cagaatcaag gagaagggag cctaaataag gagaaaaacc
     8521 atagaaaata taaagtaatt acttataaaa caagcttttt atagaaaaat aatatacctg
     8581 agtagggtat aaattaagac ggaattcctt tctagattga gatattgact aggaagaatg
     8641 ttaagatttt aagcctttaa gctaaaaaaa aacccttttt gttaaataag gggaatatag
     8701 cctgtcagtt tcaaactgca agtcgtcctg ctgcaataat atagtagatt agagatgaaa
     8761 atagattttt ttaaaccaat gactgaataa aaagaccgtc atagatacac attggaatgt
     8821 gtctattacg gtcttttttt acgaacgatt ttattgaaga cggacagttc gggtcaaaaa
     8881 taaaaaagct acgatcagaa ataagaataa aatgtatccc aaaataatgg ctagacggtc
     8941 taacttattt gtcgatagat gtttgtttag aagttgatag gcccataaac ctatcagtcc
     9001 tcctgttgta ttagttatca aatcagtgat gtccgctacg ccaataccga ataggaattg
     9061 aatcaattct gccaagaagc ttacaaggaa aataatccct aattttttag aaaaagaaag
     9121 tctcttgaaa ttgacattca aaagcacccc aaaaggaaaa aagacaatca agttataagt
     9181 ggtctcacgt aataccgtcg tattttcaaa agaaaaagta gaaaaaggga cgagattgac
     9241 attgctgtaa gaataagtga gaaattgtgg aagattaaat gatagcttga ataaaatcaa
     9301 ccataataga aagaataaat aaatccctaa taaaaatttt gatacatacc gcatagacat
     9361 ctcctccatt taaaaagtat accatcgaaa accgctgaaa aatcataaaa aagtatgaag
     9421 tttaaggacc aacgtagtta tcgtacgaaa attagaagct tttttttgtt gggaatccgg
     9481 tttctttaac aaagctaaga tagcgagttg cttggaaaag ttgctatctt ttttctgtca
     9541 aaacgactcg gaatgttcgt tttttgttct aatttctcca agttgtttac tttttgatac
     9601 taagtttatg aaaaatcaag aaatagttgt tatactaggt aatgctgaca aacgggattg
     9661 gcatttcatc ttggttcagc tttttttcca attactagga aggagggata gattgttcaa
     9721 gacttatttt cgtttcaata aaatacaaga taatcctttt cgtatcatga atctgatgct
     9781 acttatcttt attgtattat ggttaggtta cataaatcat gattttttga tttcaagttt
     9841 ttcatcatta gggatcttta cttttttcta ttatcaaaac ataccgatga aatatttgct
     9901 gaaacgtatg tttctgatcg gttgcggact gttggttgct ttcgttttgg ggatcttatc
     9961 gacttatgtt ttatggcttg aaccatttgc cgtagctttg gttgcttttt ccagcagatt
    10021 cgtgttgcga ttattccata tttctaaacc aggtggcttg ttttttgcga tgctttctgc
    10081 catgggaacg agcatgcagc tgccaatcgc tcaattaccg atcgtctcac tttatttttt
    10141 tatgggtgtc gtttttgccc tgattgcggc agtgattaca aaattactgg attcacggcc
    10201 tgagcagaca attgaaaaag caactttaaa agaaagattt cacgaagagc ctttagtgat
    10261 cattgattct gttttctaca gcgctgcctt atttctttcc gtttatgtca gtcacggctt
    10321 gaatctgcat aatccttatt ggttgacctt gtcatgtgca tcgattttgc tagcagaaaa
    10381 cttggatgcg atgaagcatc gacaagtcca atatctgatt ggatcgatgg gtgggttatg
    10441 tgtgtcggca ttcttgtcat ttgtgccgtt tacgcagttg cagaccattt ttctgatcac
    10501 ttttctatat ggaatcgcac aatttctagt tgctagaaat tatgcagttg ctaatatttt
    10561 tcttaatccg atggcgttga tgctatctac acttattcgt ggagcatact tgatttcttt
    10621 gatcgaatat cgttttttag ggatcgtcat aggaagtttc atcggtttag gtgttgcgtg
    10681 ggtaatgacg gttggtttgc aacattattt aacggttgtt cgtcaaaaat tagaatagaa
    10741 ggacaaatat atgtgccaaa agaggttatg acaagatttt tgtcacaacc tctaattcaa
    10801 ggtgttcaaa agccagattc tcagcattaa gtcaaattca cacaaaaatg tggaaaggaa
    10861 ctttcaaaaa aattttatat ttattctatc aaaaaatttt gtttatgatg gtaactgaat
    10921 aaactttcct gagatggtca atgctttcct tgaaagtctt acagatattc tttcttcata
    10981 gaaagtttaa gttttatagt tagtgtacaa taaaagtatg tttataccat atggtgtccg
    11041 gataatcagt catttaaaca atgaggttca aagatatgaa aaggggaaat ttgatgaaga
    11101 aaataagcaa tgaaatccaa attctggcag aaactttaac tcttcccaaa gtcgttatag
    11161 agcaaatgat tgtacaagca aaaaacatcc ttgatgaggt gtttgagcaa tatagtcatg
    11221 aactaatgga tcctaataaa gcaaaggcga ctgcaaagaa aatagacaaa gtctatgaag
    11281 aggaaccttt tgcagcatta gctatttatc tatatgcagc ttctcaaagt tggaaaaaaa
    11341 tttatcaacc attgaagatt ccaagaacta tctatttggc aacaatgaat gcttttacta
    11401 gatttattca tgaacatttc caagtaacag gaagctatcg ctttgaccgt ggtttttgga
    11461 tttggcatta cactagtggc ttgatctttc ggattggtga attggagtac gaaatgacat
    11521 attttccgaa agggtacacg gatctaagat tagaaggaaa gcagtgcctt tctcttcata
    11581 ttccttccga tgcagattta tctcagaata agataagaga tagttacgaa agtgccattc
    11641 gtttttttga actttatttt cctgattacc attaccaagt gatgtacaca gatacttggt
    11701 tactatcacc caatcttact aaatggttga aaaaagagtc aaaaatctgt ctttttgcag
    11761 ccgattatcg attattatca gttgatgaac aggacgatag tggagtccct tggatctttg
    11821 gacgagtaga tgcccaaata catgattatc cagaaagtac gagtttacag cgacaagcaa
    11881 aagagcaatt gcttgcaggc gagcacattg gctctggctt aggtattctt acttcataag
    11941 tttagtactt cgaaatagtt taaaagagcg tgagacaaaa gtaaagaaca cttttgtctc
    12001 acgctctaaa cacgtataaa cggcggaagc agaagcaact ccttcggaaa taagctgaaa
    12061 ttcacaaaaa tttgaaaagc aattttcgtg aatttcttct tatttcttgg agttaaacgc
    12121 ttctgtccca gcctcttttt tagtgttcta tcgaacacac agtacgttca ataggtaaac
    12181 tagctataac aatagatatt aaagttaacg gacaagaggg ccttttttag gtagctaaaa
    12241 cgtaataatg aaaatttatt tccagagata ggagtcaatc agctagtctg atcgactgtt
    12301 ttaacaagtt gactttcatt ttaacttttg ataccattta aaacacaaat cgtaattgtt
    12361 tcgatttgtg ttttttagca tgactacaat caaagaagaa agtgggtcgt ccatatggaa
    12421 aaaacagata tctcaagtgc ataccgccgc ttgaaaagcc caaatatcaa aacacgaaaa
    12481 cgtgcgctga agatcatcaa agatgtgaaa cggaatagtg ggaaaaggta agaagaagga
    12541 aacttaatta aaaaaatagc cgaaaaacgt ttttcggcta ttttcaataa tcggtttttg
    12601 tgtaaggttt ccgaaagaac tgctgttgat tttccatttt taacatatga taaattggta
    12661 gaatctttct tttcaaattg ataccattcc ctaattccag ttatatagtt aactacagaa
    12721 ccacaaagca cgtacgttta taaaagtatt atctgtagtt atttttcaat tccctttcaa
    12781 cctcttattt tgaccagtag tattgatcac tttacctttt aacacctttg ttcgtttttg
    12841 aaacattttt agtcaagaat ggaaacgtaa ctacataatc aaaggttttg cgaaatattt
    12901 catgaaatat ttcatgtaga agcgagcaat acggttgcaa ataaccatta tcgtttaata
    12961 agcagttacg aaagctccca atatctctaa cgttcagctc actccatttc ttttcttcaa
    13021 aaaaatcagt gattcgtatc tctttctatt tgtcgaaaaa gttaacttta aaaagtaacg
    13081 ccgaaaaaat atgcaaaaaa ataaaaaagc agttactatt gctagaataa catcaaggaa
    13141 taataagttt tggttttcag ataatagtcg ataagttgtg tattggaatt ttagatacag
    13201 taataaagta tttttcatga aattttgtga gaatcactat tacaagtatc tttaataaaa
    13261 ttaatggtta aggaggaact taaagtagaa tgtaaatgaa tagttgtagt cagtcgattg
    13321 tgatactaga ctcaaagttg caggaataag tttttcaatt tgtgattgga agataaaaaa
    13381 tgaaaaagaa gggctttttt ttatactttg ttgattgtag tgtttatttt ccctctgttt
    13441 agccaagtaa cattttctat gactcaacca gtttcaagtg aggaacatga taaccttttt
    13501 cgtgctacag aagagtttaa gaaatatcag gaaaatattg ttccggagac tccattagct
    13561 agtgagccaa ttactgatat tgatggaaac caaataggat ggtatataca gtacgaagtt
    13621 atggtggtaa ataatgactc aatagtaaaa aatacagtag gcttagagct aacaccgatt
    13681 gaaaaggtga gttcattgtt aacgtatatt tatactgatg aaagtgacga gactgagatc
    13741 attttaacgg attactcaaa aattgctact gataaaaagt atatattgtg gatgtagaca
    13801 ctagtgaaat actttatgat atagaaattg atgaaaattt actagatgta gcacaagaaa
    13861 tcgatcatca aaagcaggaa gctattcgat atgctggtag aaaagggaaa agaaaatatt
    13921 tattacgtga atgtagcaaa agttagagaa gatgaaaatg agtggaaaga attcaagagt
    13981 cgctactcaa ttaactcgac tccgacattt acagtttaca gagaaggatc gatagaaaaa
    14041 actgtttttt ggactaaaga aagtggaatg tctttagctg aagtagaaga gtttttggat
    14101 tatgttagta tgcaacagta agggagttct tattatgaaa aattttgaca catattatgt
    14161 tattgttttt tcgatatctt tgctgttaat attactaact ttaatgcagt ataaagagta
    14221 tccagagtat tttattttaa cttttgtata tttagtaagt agctacacac ttctatataa
    14281 attcagaagt tcttctagag tttctaaagt ttgtttctta attagcttat tgattctata
    14341 atatttttga tttatatagg aaattaaaaa tattatagaa tcaacactca gagaacgggt
    14401 tggtttttaa tagatttaat aagtactgat aatgaaattt ctcctggttg ggaaaacgaa
    14461 gttggttacc ctgtagaaga attttttcaa gattactttg cggagtatgc cgataggata
    14521 atgagagatt acgtaacaga taaaactcaa gaagtcatca atcaatccca gtcattaaat
    14581 gaattatctg ataaggcgaa agaagaagca gttgccatta tttcttcagg gattagtgac
    14641 tatattgata tgagtggtga aatcaattat ggcgataaag acaaaattgt acgcatgata
    14701 aaagctttta tcaaaacttt tgatgtgaag gcagatctta agtttaatga tacttaccta
    14761 gtaggaaaat taattaatat ccttgggaca gagaaagata cggaaacgtt tatttcctct
    14821 ttgtctatgt tgtttacaga taagcatttt tcaactcagc ttggtggaga ggaactagtg
    14881 gaaatctttt aaccattacg cccagcatta ataaaagtat atcaaaaaag tactcctgat
    14941 gatttttaag attggtttga gaaataatgt gaaaacacta tttttaatgt taattataga
    15001 tagagatgaa cgcgtcatat ggttaaaaga atgaaaaagt caaagataca ctgctatatt
    15061 tcactaagga tatagcagtg tatctttcat gtcgtttcac tggcagtttt ttataaaagg
    15121 aggtgtgcat ttcagttgct tttctttggt agttagttga atcgtttaag aattaacgga
    15181 tgtggcagac aggtgctctg tccaaaaacc agtaaaatct ttgatggttc catctttatt
    15241 tagctgtgcc tgttcaaata ctgttttgtt tttaccgaat ggatcaattg caataattgt
    15301 tccgatcccc gcacgtttgg cagcaagtaa tcctgagtaa gcatcttcga taacaagaca
    15361 atcagccgga gctaagctca gtttgtctgc cgctttaaga aaaatatccg gttgcggttt
    15421 cccagggaaa gagccgtcgt catagacaat cttgtcccag tcaaaccagc gggctaaatc
    15481 gaaaatatca aaataaaaag caacattctc tttgacagta gccgtggcaa tcgttaatgg
    15541 aatctgttgg tcagtcagct ggtcaagagt cgcttcaagc ccttttgtca actgaagctc
    15601 gttttcattt tgcaagcaaa gcatacgata atagctttct ttttcttctg acaatacggc
    15661 gatctcagag gcggtcaaat gctctgaaat gaaatgtttc aaaatctccg tattcgtccg
    15721 accatgaata ttttttaaaa tatcctcgtc tgataaacca tcttttgtat gatcatgtat
    15781 catatgcagc caagcagctt catgcagatg agagtccaaa aacattgttc cgttgaaatc
    15841 aaatataatc cctttcatag ttacgctcct atagtggtat tttcggttga atcagcaatt
    15901 tgcagatcga catattgtgc atagtgctct tgaacctccc gcgagatctg gcgatccgta
    15961 atgagcagat cgaaatcatg caaattataa aacacataaa aatcatctcg attgaatttt
    16021 ttattatcaa cgagtagata tttcttacgg gaattattta gagcgatctg ctgtgcttct
    16081 ccttcttcgg tactgtaagt agagatcgct tcgttgtgaa cgccatttga actgataaat
    16141 gcttttgtaa actttagtct tcttaaattg tcgttggtga tcggtccgac aaatgcgccg
    16201 gtatttttcc ggaaatcacc gccaatcagt agaatttctg gtccatctgc ttgagcaaga
    16261 atatcaaaaa ctggataatt atttgtaatg atccgaattt tcttgttcag taaatgcgtc
    16321 gccaatagtt cgattgttgt acctggtcct aagaaaatcg tttctccctc gtgaatcaag
    16381 gaggctgctg tggcagcaat ttcttttttt tcttgaatct gcagagtggc tttttcagtg
    16441 tgagaaagtt cttgatctaa agtgtaggaa agactttgag cccctccatg gacacgcagc
    16501 agcttgcccg atttttctaa ttcatctaaa tctctgcgaa cggtcatatc agaaacatct
    16561 aattgattga tgatttcatt aacggtaagg attccttttt tattgaccat ttctacgata
    16621 gtaagcaatc tttctttttt caacattgtc ttcacctcta atttaaggat aatctatcat
    16681 ataaacggac aacagtcaat ctaattcgaa caaaagtaaa catttagggt ggtttttatg
    16741 tttgttacaa tagattttat tgctgttttc tggtttttat gattatttgt gtttgttttt
    16801 gttgacaaat gttttggatg cgtttacaat gcaatcagtt agaaagagcg aaaactgatt
    16861 atagatttga ggagagatgt acatgcttaa attaccagaa gattttattt ttggcggagc
    16921 cacagcagcc tatcaggttg aaggagccac taaggaaggt ggcaaaggcg ctgttgcttg
    16981 ggatgacttt ttagaggaac aagggcgatt cagtcccgat ccggcaagtg atttttatca
    17041 tcaatatgca aaggacattg aattgtgtga acgttttggt gtaaatggtc taagattatc
    17101 cattgcttgg agccgcattt ttcctgatgg agctgggaaa ccaaatccag aaggaatcgc
    17161 tttttatcat cgtgtgttcg aagaatgtaa gaaaagaaac gtaacgccgt ttgtgacgtt
    17221 gcatcatttt gataccccta aacgtttgtt tgaccatgga gattttttga atcgagaaac
    17281 aatagaagca tttgtttcct atgccatttt ttgttttcat gaattcaaag aagtcaaggt
    17341 gtggagtacc tttaatgaaa tctatccagt tgcaaccaat caatatttgt taggtgtttt
    17401 cccaccagga atcaaatatg attttacaaa gatcgtcgcc tgtcttcata atatgatggt
    17461 tgctcatgcc cgtgtagtga actatttcaa agaaaacgaa cttccgggtg aaattggtgt
    17521 agttcactca ttagagacga aatatgcggc aacagacgcg ccggaagata agcatgctgc
    17581 ctttttagac gatgcattgt cgatccgttt cttattagat gctacctatt taggctatta
    17641 ttcaactgaa accttgactg ctcttgatga gatatgtgaa gcaaatcagg ccagctatca
    17701 ttttcctgaa gaagatttcg ttgaattgaa aaaagcatcc acgcgtaatg actacttagg
    17761 gatcaatcac taccaatgcc attttgtcaa agcttacgat ggagaaaatg caatccatca
    17821 taacggtacg ggtgaaaaag ggacctctgt ttataaagtg aagggaatcg gagaacgtat
    17881 ttataaagaa ggaattcctc gaactgattg ggactggctg atttatccag aaggtctata
    17941 tgacttgttg ctgcgaatta aaagcgatta cccacattac aacaaaatct atatcactga
    18001 gaacgggatg gggtataaag atcagtttga agatggcatt attatggatc agccgagaat
    18061 cgactatttg agagtctatt tggaatcctt aagcaaggcg ataacagccg gggtaaatgt
    18121 gaaggggtat tttttgtggt cgcttatgga tcttttctca tggacaaatg ggtataacaa
    18181 aaggtatggc ttgttttatg ttgattttga aacccagaag cgttacccaa aagaatcagc
    18241 ttactggtac aagttggtca gtgaaaccaa aacgattatt taataagtga taatggagga
    18301 agaaaagatg aataaagagg aattacaaat gcttggtttt gagatcgttg catattcagg
    18361 cgacgctcgc agtacattat tgaaattatt gaaagaagta agacaaggaa actttgaaca
    18421 tgttgattcg gcgttgaaag aagccgacga aaatttaacc cttgcacata attcgcaaac
    18481 aaaaatttta gcggaagaag catctgggaa agagatggag atgggattca tttttatcca
    18541 tgggcaggat catttaatga ccactttatt gctgagagat ctgattcaag actttattgt
    18601 actgtacaga cagaatcaag gataggagaa gaacgctatg gatggaatca ttaaacaaat
    18661 cgaaaaaggg aaaccatttt ttgaaaaaat ctcacgtaat agttatttag gagccgttcg
    18721 tgacggattt ttaacagcga tgccagctat tttattttca agcattttca ttttgattgc
    18781 tgcggttcct gagatttttg gttaccaatg gcctgaatct gtctccacat ggctatggaa
    18841 agtctataat tattcgatgg gtgttgtagg gttactcgtt tcagcaacca ctgctcgctg
    18901 cttggctgat tcgatgaatc gtcgcttacc gaaaaacaaa gtaatcaaca ccacctctgt
    18961 gatgctggcc tctgtggtaa gtttcctgtt gttaagcgtc tctccgattg aaggtggatt
    19021 ttcaacggaa tatatgggga caaagggact actggcttcc tttgtcgctg catttttaac
    19081 agttaattta tataagtttt gtgtgctgaa agatattacc attaaaatgc ctaaagaagt
    19141 tcctggaacg atttcgcaaa ccttccgaga tatttttcct ttctcttttt cagtatttgc
    19201 ggccgtttta attgatttag gcattcgaca aatcttccaa atctcatttg cagaagcaat
    19261 cattacggtg ctgcagccgc tatttacagc agctgacggg tacttaggaa tcgctattat
    19321 ctggggagcg atggcgctgt tttggtttgt cggtgttcat ggaccgtcga tcgtggagcc
    19381 ggcaattgcg gcaattatct atgccaatgt ggaaaccaat ctgcaattgt tcaattccgg
    19441 tgaacaagct tctaaagtac tgacggtggg tttagggaat tttgtaggaa ctatgggagg
    19501 aactggggca acattggttg ttccttttat cttcctactc tttgctaagt ctaagcagtt
    19561 gaaggcagtt gggaaagctt cctttattcc agtaagtttc gctgtcaacg aaccattgct
    19621 atttgcggca cccatgattt tgaaccctta tttttttatt ccatttttgt taacacctgt
    19681 tgtaaacgtt tgcctgttca agttttttgt cgatgtattg ggcatgaaca gctttatgta
    19741 cgttttgcct tgggcaactc cagcaccgat cggtttggtt ctaggaacgg gcatgggtat
    19801 cttagctttt gttctagcag cggttctaat cgtcgttgac ttcctgatct atctaccatt
    19861 ttgcaaagca tacgatgctg tcttagtaga gaaagaagca caaaaagcag aggtgatcgc
    19921 aaccgaggaa ggtgcttctg ccgatgtacg tgaggaagta cctgtggcag cgagtcaagt
    19981 tatcagcgat gcaaataaag aaatcaatgt gttggtactt tgtgctggcg cagggacaag
    20041 tgcgatgtta gctaatgctt taaaaaaagg tgcatctgaa tcgaaagcac cgatcagtgc
    20101 aatggcgggt gcttatggtt ctcattacga aatgctgcag gattttgata tggtggtctt
    20161 agcaccgcaa gtcaattctt actatgatga tatcaaagaa gacaccgatc gcttaggaat
    20221 caagctggtt gcgacaaaag gagcagaata tatcggatta acgagagatc ctgaaaaagc
    20281 tgttcagttt attctgaacc aatttcaata aaggaggagc cataatgaaa atgggaattt
    20341 ggttgcgtaa agctgtttta tttgcagctg tgttaggggc tttgggggct gtttcaaaaa
    20401 ctgttgaagc atctgccagc gaatttattc gcggagcaga tatttcgatc ctgtcagata
    20461 tggaaaaatc tggtgcaaaa tattatgaag acgatatttc aaaagatgcc ttagagattt
    20521 taaaaaataa tggtgtcaac tatgttcgac tgcgtttgtg gcaggatcct tataatagta
    20581 atggagaaag ttatggagca gggacaaatg atctggaaac gacgattgac cttgcaaaac
    20641 gagcaaaaaa tctgggactt aaggtgctgc tggattttca ctacagtgat ttttgggttg
    20701 atcctgggaa acagaatctt cctaaagcat ggcaaggtct gacctttgaa gaaatgaata
    20761 cggcattgta cgactataca aagaacgttc tgtcggaaat gaagcagctg gacgtttatc
    20821 ctgatatggt tcagatcggc aatgaactga atagcggaat gctctggcct tatggcaagt
    20881 cttggggaga aggcggggga gaatttgatc gattggctgc ttttttgaag tctggtatcc
    20941 aagctgttcg agacactcaa cctaaaacaa ctccagtaat gctccactta gctgatggtg
    21001 gcgatacagg agcatttact tggtggtttg atgaaatcac gagtcgaggt gtgtcatttg
    21061 atttaattgg agtgtcgtat tatccgtatt ggcacggttc aatgaatgaa cttcaaacca
    21121 atatgaatgc gatcagccaa cggtatggta aagaagtgat cgtagttgaa acagcttatg
    21181 ggcatacaac agcgaatgcc gatactatgc caaatgcttt tggtgaagcc gaagcagctg
    21241 cggggggata tgaaccaaca ccgacaggac aagcagagta tttgctggat cttgccgatc
    21301 ggattcaggc agtaccgaat aatcgcgggg cgggcttctt ctattgggaa cctctttggt
    21361 acaacggaaa tgtgagttgg gcaacacaag caggtatgaa ttatctcagt gttcaatcca
    21421 ctatgggaaa cgaatgggac aaccaagcga tgtttgattt tgctggaaac gccttgccaa
    21481 gcttgcgtgc gtttaaacaa gcaggggcgc aaataaatct agttaaaaat gcaagtttcg
    21541 aaagcgatgg accaacgacc agtccttcca attggcaaac ctggtttcaa caaggaaccg
    21601 ctaagggtac gatcaaaacg gaagcgggca ctttttttgg ggactacaaa ctaacttttt
    21661 ggcaggatca agcatacgag gcatcagctt atcaaaatgt tagtggcata agcaaaggaa
    21721 cttacacatt gagtgcctat gtaatgtctg ggggagagtt tgatactaat cagttatata
    21781 tcaaaaatta tggtggagcg gaactaaata ctgcggttgt taaaacaagt gaatggacaa
    21841 aaattacaat caaagacatt ccaattacaa caggtgtttg tgaaattggg gtttatagca
    21901 aggcttcagg aaatgcttgg acgaacgttg attttgtttc attggtgaaa caatagactg
    21961 cggatcgttt cgattcaaga tcggaggttc ccttcagcca catcgttagc gtagaaggca
    22021 ggaatcgaac ctgcacctcg cctttgccaa aaataaccag aaacgatttc cagtcatttt
    22081 taccaaaacg agtaaagcac cagacttcat ctacactttg tattatgcta aagagagttc
    22141 aacgatttcg taagaagcaa tgaaaaaatt gcaaaaagtt gtgcagataa cataaagttt
    22201 gtttaagaaa gggtaacctt agaattccgt cgtgaatatg atttgagcac ttagatggat
    22261 agaaaaaagt tctcggaaaa cagttcgttt ttcgagaact tctttttatg ataagaatga
    22321 aacaaattaa cttatattat agtctctttt ggtagggaac catcttattt ttaatgaaaa
    22381 tcaagcattt tagctattga agaatgttga tttataggga ttccccctcc atattatgtt
    22441 ggctctttat tcccactcca ctgttgctgg tggtttagaa gtgatgtcat acacgatacg
    22501 gttgacgtgg gctacttcgt ttacgatacg tacagagatt ttttgcaaga cttcccatgg
    22561 gatacgggca aagtcagcgg tcattccgtc gattgaagtt acagcacgga taccgactgt
    22621 gtagtcgtaa gtacgtccgt cacccataac accgacagag cggatccctg gaagaacagt
    22681 gaaatattgc cagatatcac ggtcaagtcc agcagctgcg atttcttcac gcaagatagc
    22741 atcagattcg cgtacgattt ctagcttgtc ttcagtgatt tcgccaagaa cacgaatacc
    22801 aagaccagga ccagggaatg gctgacgcca aacgattgaa tcaggcatgc ctaactgagt
    22861 ccctaattca cggacttcgt ctttgaataa tgtgtttaat ggttcgatca attcaaattg
    22921 catatcttct ggcagtccac ctacattatg gtgagatttg atcgtctgtg ctgtttctgt
    22981 accagattcg ataacgtcag tatacaacgt tccttgtgct aggaaagaga cgccttcttc
    23041 accagcaagt tttgttgctt cgtcatcaaa aacatatacg aattcattcc caatgatttt
    23101 acgtttttgt tctgggtcag atacaccttt caacttgtct aagaagcgat ctcttgcatt
    23161 gactttgatg atgttcaagc cgaattttcc gcctagactt tccattactt gttccgcttc
    23221 gcctttgcgt agcagaccgt ggtcaacaaa gatagatgtc aattggtcac cgatcgcttt
    23281 ttgtaaaaga accccaacga cactagaatc aacgccacct gaaagaccaa gcaagacttt
    23341 tttgtcacca acttgttcac ggattttttc tacttgcata tcgataaagt tatccattgt
    23401 ccagttacct tcacagtgac aaacatcaaa ggcaaagtgg cgcagcaatt cgattccgta
    23461 ttcggaatga cgtacttctg catggaattg gataccataa aaattacgtg ttgtgtcttg
    23521 gatagaagca atcggacaat ctttgcttgt tccgactgtt tcaaagcctt caggaacttt
    23581 agttaccaag tcaccatggc tcatccatac tgtttgttgt tttggtgttt ctttaaacaa
    23641 gacagcttga tcgcttgtta cttctaacaa ggctttccca tattcgcggt ttttagcagg
    23701 ctctacggaa ccgccaagtt tgtacgtgat caattgcata ccatagcaaa tccctaatac
    23761 aggaatacct aaattgaaga tctcaggatc gatcccaaat gcattctcat catatacact
    23821 gtttggtccg ccagaaagaa tgattccctt tggattcatc gcttttactt cttctgcagt
    23881 aatgcggtgg ctcaataatt cggaaaagac tccaagatca cgaatacgtc ttgtgatcaa
    23941 ttggttatac tgactaccgt agtctaatac gataatcttt tcaacgttcg tcatatcggc
    24001 aacgtttgtc aaatttatta cccctatccc tttaaatttt atctcaaaat agtcaaacta
    24061 ttttaaaatg ctaatatttt cgcatgaaaa tcgaatcgat gatatgattt tcagttttat
    24121 ggagaattat atcggctctt cctcgtgtag gcaagatata ttcctgtaaa tttttcaaat
    24181 tcacattttt ccatacatct tttgccattt taaaggcttc ttcacgatct ccgatagcaa
    24241 aacgataata ataattctct ggattttgga aagccgtatc cagtaacgca ccaaaacgat
    24301 ccaaatacca tttttcgatc agcacgggat cggcatcgac atagacagaa aaatcaaaaa
    24361 agtcgctgac gtagatttgc tgattcgcag gtaattgaag cgtattgatc ccctcaacga
    24421 tcaagatatc aggctgctgg atcaattcgt acttgtctgg aatgatatca tacacatcat
    24481 gtgagtaaac aggtactttt atctcttcct gaccagattt tacacggttc aagaaatcga
    24541 tcagcatctc catatcataa ctttcaggaa atcctttacg gtccatgatt ccacgctctt
    24601 ttaatatacg atttggataa agaaatccgt cagtcgtgat cagctgaacg tttcttcgtt
    24661 tgaaggtacg agacaaaatc gtctgcagca gtctggctgt tgtacttttt ccaacggcta
    24721 cacttccggc gatcccgata ataaaaggcg gtacttctac gtatttatga agaaataaac
    24781 ctttactcaa gaacaaagat tcaaattctt tcatataaag ataaatcaga tgagcaagag
    24841 gtacatagat atctcgaaca tcctgcatgg aaatgcggtc attcaaactt ttgatattat
    24901 ctagttcatc ttgtgtcaaa ggtgcttgcc cattacgata aaattctcgc cattcttctc
    24961 ttgccacacg gtagtagttc attggatcat tcatattagc ctcctgcgtt ctcccatcaa
    25021 tggaactatt ttaacacaaa ataaacgcaa accccaccac ttaagagaga ttgccgatct
    25081 ttttgtataa tctttataat agaaagaaac ggagtcttat tcttgacttg cgcacggata
    25141 cataaaagga tagactgttg tcatgaaaga aatgagaagg atggaagaca tgacaaatca
    25201 ttactattct gaacgcccag atacggcgca cgattttgaa caatgggctt ttgagttaaa
    25261 aggcagaacc tttcaatttg taacagattc tggtgtattt tcacgtgaaa cagtggatta
    25321 tggttcacgt gtcctgattg atgctttcga ttgggaagag ttacctgatg aaggaaagat
    25381 cttagatgtg ggatgcgggt atggaccgat tgggttagct ttggcatttg cgacacagcg
    25441 gtttgttgaa atggtcgaca ttaatgaacg agcggtaagt ctagcgcaag gaaacgcaaa
    25501 gcgtaaccaa atcgaacatg ttgatatcca tcaatcgaat atctatgaag cagttcatga
    25561 agaaacctat gcagctatcg taagcaatcc gccgatccgt gctggaaaaa aagttgtaca
    25621 tgaaattttg acaggcgcat atcctcggtt gaagaagggc ggtacactga caattgtgat
    25681 ccagaagaaa caaggagcgc cgagtgcgca aaagaaaatg gaagaaacat ttggtaatgc
    25741 agaaatcgtc acaaaagata aaggatatta tatcatcaaa agtgtgaaag aataactagc
    25801 tgaaaaatag tggagcgacg aaagagtgga actgggcgtg catgtacggg tacgtatcag
    25861 ttcttttttt gttgagaagt ttttaaaaac aaagaactat tttttcttca aaaagaaata
    25921 gtaggaacag agtcgttgtt ttttacgata aaataaataa gatacagaac ttgtatagaa
    25981 gactgccaag tcggtagata aaggaggttt ttatcaaaaa acatactttc cttttttctc
    26041 tattcttttc ttgggggttt tggtacactg atagggaatt tagatagaag ggagccaata
    26101 ggatgaagct gaccatcaga gatatcgcag aaatggcagg cgtatcagta acaactgtct
    26161 cacagatttt gaataacaaa ggaagcagat ttagtgataa gacaagaaaa aaagtgttgt
    26221 cgatcgtgaa tgaacatcat tataagcccg attatttcgc ttcaaatgtg atcaatcgac
    26281 attcaaagac catcggaatg atcgtccctg atgtcactga tttcttcttc tccaaactga
    26341 tcgaaggtgt agagagctat ttgaatcctt tgggctatgt gatcatgtta tgcaattctc
    26401 gtcatagcca agaaaatgag atcaagtatt tacaagagct ttcccaccgc tcagtggacg
    26461 gaatcttgct ggccacacca aatattttac ctgagaaata tgcattagac agcggttttt
    26521 atcaaaaaat gccaatcatt ttaatcgatc gcggattgaa tcgtcgggat aacggacggc
    26581 ttatcgtaaa ggaatatgag ggcgcctatc aagctgtttc gctgtttatt gaaaatggcc
    26641 atacgaagat cggcatgctg aaggaaacca ctggatacta tcaattagaa gaacgtttca
    26701 acggatatcg tcatgcgctg aaagatcatg gcctgccttt taatgggaaa tttgttgaac
    26761 atggagagtt gactgtccaa ggtggatata ctgcatcaaa aaaattactc aaacataaag
    26821 atatcacggc tattttttgc gggaatgatg ccatggcgat cggatgctat caggcgatcg
    26881 atgaattggg caaaaaaatc ccagaagata tctcagtcat aggattcgat ggattaaagc
    26941 tgtcagaata catgattccg caattgacga cagtgcagca gccaagtttt gatattggat
    27001 tttatgctgc acgtttcctg atcgatacga tcgaatttcc tcaaagaaaa gttccgaaca
    27061 aagtgttcga aacaaaatta attattcgtg agagcgtaaa agtattgaca aagggctaac
    27121 tcggcggtat attgcttatg taagcattta caaaggctag ttagtgcttt ttttattttt
    27181 agtaaaccag tttactaaag tggtttacct ttcctaaaaa taatgtataa taccgaatga
    27241 agacaaggag gatcaggcaa tgcgaatggt ggatctgatt gaaaaaaaga gggatggaaa
    27301 cgagctgtcg aaagaggaaa tcgagtacat cgtcacgaac tatacgaatg gaaagattcc
    27361 agattatcaa gtcagtgcat tattgatggc aattttttat caagacatga caaatgaaga
    27421 aatcacgaac ttaacattgg cgattgctaa ttctggtgat gtcatcgatt tgagttctct
    27481 tgaaggaata aaggtagata agcattcgac aggtggcgtt ggtgacacga ccacattgat
    27541 tttagccccc ctagtagcta gtgtcggagt gacagtggct aaaatgtctg gacgcggtct
    27601 aggttacaca ggtggtacac tagacaagct agaagcaatt cccggatttc agatcgagct
    27661 ttcggatgaa gaatttgtac gcattgttaa tgaaagtaaa gtagcggtaa ttggtcaatc
    27721 aggaaacttg gcaccggcgg acaaaaaatt gtatgccttg cgtgacgtca cagcgaccgt
    27781 tgattctctt ccgctgattg ccagttcgat tatgagtaaa aaaatcgcgg caggagcaga
    27841 tgcaatcgtt ttggatgtga ccactggaga cggtgctttc atgaagaaca tcgaagatgc
    27901 aagacgtctg gcaaagacca tgacgagcat tgggaaactg gctaaccgag aaacagtggc
    27961 ggttatctca gatatgtcag aacctcttgg cgaagctatc ggaaatagtc tagaagttgt
    28021 cgaggcaatc gaaacattac aaggaaatgg tccagaagat ctagtagaaa tgtgctacgc
    28081 cttaggaagc caaatggttg ttcttgctgg caaagctaag acaaccgatg aagcaagaac
    28141 gttgcttcaa gaagctctgg aatcaggtaa agcgttagca aaattcaaag aaatgatcca
    28201 aaatcaaggg ggagacccag cgatcgtgga acatccagaa cgaattttga ctgcacgcta
    28261 cacaatggag cttcctgcta aacaaagcgg agttgtgtca aaaatcgtgg caaatgaatt
    28321 aggaattgct gcaatgatgc taggtgctgg gcgtaaaacc aaagaagaag atattgatca
    28381 cgctgttgga ttgaaactgc ataaaaaaat tggtgacact gtgacaaaag gtgagtcact
    28441 attgacgatc tatagtaacg acgaagaaat cacttctgtc attgaattat tatataaaaa
    28501 tattgaaatt ggtgaatcgg caatgaagcc aacgttgatt catgacatca tcacagaata
    28561 aaggaaaaaa gcggacttta ccgttttaaa gaaaagggga aaagaaatgg aactaaaccg
    28621 aatgatcgac catactattt tgaaagcaga cgcatctaaa gaagctgtga tgcaaattat
    28681 cgaagaagca aaaaaatacc atttttattc tgtctgcatc aatccagcat gggttgcgct
    28741 agcgaaagaa caattacaag gtgagccagt agccgtatgt acagtaatcg ggtttcctct
    28801 aggagcaaac acacccgaga caaaagcatt tgaaacaaca gatgccatca ataacggtgc
    28861 agatgaagtc gatatggtca tcaatatcgg tgctttgaaa tcaaaggatg atcaacaagt
    28921 ccaaaaagat atcgaagcag ttgttgaagc agcaaaagat cgtgcgcttg tcaaagttat
    28981 tattgaaaca tcgttattag atagagaaga aatcatccga gcttgcgaaa tagcaaaagc
    29041 tgcaggcgct gattttgtca aaacatcaac tggtttctca acaggcggag caaaggtaga
    29101 ggatgtccgt ttgatgcgtg aaactgtagg accagaaatg ggtgtcaaag cttccggcgg
    29161 tatccataac gaagaagaag caatggcaat gatcgaagct ggtgctacaa gaatcggaac
    29221 aagcgcagga gtagcaatcg tatctggttc aactggtgaa ggctattaat tttttcaaag
    29281 gagaagctca tggcagaact caaacaagaa tggatcaaca cagctattga agcgttagat
    29341 aaagcctatg ttccttattc ccattttccg gtaggcgctt gtctcgtaac ggaatcaggc
    29401 aagatttatc aaggcatcaa cattgagaat gcatcatttg gattaacgaa ttgtgccgag
    29461 cgcacagctt ttttcaaagc agtatctgaa ggagaaaaaa catttacgca tctagtcgta
    29521 gcggggcaca cccccgatcc tatctctcct tgtggtgcat gtcgacaagt aatggcagaa
    29581 ttctgttccc ctgatatgcc ggttacgcta gtaggagaca atggtgtgac gaaggcaacg
    29641 accgttcgtg cactgctgcc ttatgcattt actgaaaaag atctataact catgttcatt
    29701 cagtcagctg actgttgaaa aataaaacaa ttattttagg aggctttaca gaaatgaaaa
    29761 aagcaaaatt atttggttta ggtgctgtcg cactagcagc agggttattt ttaggtgcat
    29821 gcggcaacaa cggctctact gattcatccg gtggcaaaag ctcatcagac acaacaactg
    29881 cagcattgat cacagacaca ggtggtgtag acgaccgttc attcaaccag tcagcttggg
    29941 aaggactaga aaaatggggg aaagatcaag gactttcacg aggaaatgat ggcttccaat
    30001 atttccaatc ttcaaatgaa tcagattaca tcccaaatat tgaccaagca ttgaatgctg
    30061 gattcaaaac gatttttggt attggttata aactaaaacc agcgatccaa gaacaagcaa
    30121 caaacaatac aggtacgaac tttgttatta tcgatgatgt catcgatgga ttagataacg
    30181 ttgtatctgc aactttcaaa gacaacgaag cttcttatct tgcaggtgtt gcagcagctt
    30241 atacgactga aacaaacgta gtcggcttta tcggcggtgt aaaaggtgaa gtaatcgatc
    30301 gttttgatgc tggattcaaa gccggtgttg atgcaggtgc gaaagaatta ggaaaagaaa
    30361 tcaaagtatt gaatcaatat gctggtgact tctctgctcc agataaagga cgttcaattg
    30421 ctcaaggtat gtatgcacaa aacgcagata tcatcttcca tgcttcaggc ggtacaggta
    30481 acggtgtatt ccaagaagca aaatcattga acgaatcagg cgacaaaaaa gtttgggtta
    30541 tcggtgttga ccgcgaccaa tcagacgaag gcgaatacac attaaacggc gaaaagaaaa
    30601 acttcacatt gacatctaca ctgaaagcag ttggaacagt agtagaagat ttggcacaaa
    30661 aatcagcgga cggtaaattc cctggcggcg aacacactgt ttatggattg aaagaagacg
    30721 gtgttggtct aacagaagga caactttctg acgaagcgaa aaaagcagtt gatgaagcaa
    30781 aagaaaaaat catttcaggt gacgtaaaag ttccagaaac tcctgaagaa aactaaaacc
    30841 atttctatag ccttgttaga cacatgtttg acaaggctat ggtttgatta gaacaagaat
    30901 tgttcattta tccaagctgc cttgtgacag tttggataag ggaacaactc cctgaagtaa
    30961 tgtttgtttc aaaagaagaa cgctcactaa gcgtgaatct tagtcaatcg ttgccctaga
    31021 tagaaatcgt taggatgtga aaaaaaggtg gttcaagaaa atattgtcat agaaatgcag
    31081 aatattacca aagaatttgg aacattcaag gcaaatgaca acatcaattt acaagtaaag
    31141 gcaggagaaa ttcatgcgtt gcttggagaa aacggtgctg gcaaatctac attgatgaac
    31201 gtgctttccg gattattaga gccgacatca gggaaaattt tgatgcgtgg gaaagaagta
    31261 aagatcacaa gtccgaccaa agccaaccaa ttagggattg ggatggtcca tcagcacttt
    31321 atgcttgttg atgcctttac tgtaacagaa aacatcgtgt tgggaagcga gcctagtcgc
    31381 gcagggatgc ttgaccataa aaaagcacga aaagagatcc aaaaagtttc tgaacagtat
    31441 ggattgtcag tcaacccaga tgcttacgtt cgtgatattt cagttggaat ggaacaacgg
    31501 gtagaaattt taaaaacact ttaccgagga gcagatgtac tgatttttga tgagccgaca
    31561 gctgtattga cccctcaaga aattgatgaa ttaatcgtga tcatgaagga attagtcaaa
    31621 gaaggcaagt cgatcatttt gattacgcat aagttagatg aaatcaaagc agtagctgac
    31681 cgctgtacag ttatccgccg tggaaaagga atcggtacag tcaacgttaa agacgtaacc
    31741 tcacaacaat tagccgatat gatggttgga agaacggttt cattcaaaac gatgaaaaaa
    31801 gaagcgaagc ctcaagaagt cgttttgtct attgaaaatc tagtggtgaa agaaaatcgt
    31861 ggattagaag ccgtgaaaaa cttgaactta gaggttcgtg ctggcgaagt acttggtatc
    31921 gctggaatcg atggaaacgg gcagtcggag ttgatccaag ctttgactgg tttgcgaaag
    31981 gcagaaagcg gacatatcaa gctaaaaggg gaagacatca ctaataaaaa accccgaaaa
    32041 atcactgaac atggtgtagg acacgtgcca gaagaccgtc ataaatacgg gttagtccta
    32101 gatatgacat tatctgaaaa tatcgcacta caaacctatc atcaaaaacc ttacagtaaa
    32161 aacggcatgc tgaattattc agtaatgaat gaacatgcca gagaattgat cgaagaatat
    32221 gatgttcgaa caacgaatga acttgttccc gcaaaagctt tatcaggcgg aaatcagcaa
    32281 aaagcaatta tcgctcgtga agtcgaccga gatcctgatc tgttgattgt tgcaaatcca
    32341 actcgtggac tggatgtagg tgcgatcgaa tttattcata aacgtctgat cgaacaaagg
    32401 gacaaataca aagcagtgtt actgatcagt ttcgaattag aagaaatttt aaatgtttcg
    32461 gatcgtattg ctgttatcca tgaaggagaa attgtcggta tcgttgatcc gaaagaaaca
    32521 tctgaaaatg aattaggtct attgatggcg ggctatacct tagaagaagc acgaaaagag
    32581 ttagaaaagg gggctggcgc acatgaatga tcgcagcgaa aaattccgta atttattagt
    32641 gcctgtactt tcagttgttt taggattgat cttaggcgcg atattgatgg ctgcttttgg
    32701 ttttcagccc atccaaggtt attcttctat gctagatgca gcccttggtt cgcaaagagg
    32761 gataggtgaa acgttaaggc aagcaacgcc gttgattttt acagcattag gtttttctgt
    32821 agctaactca gctgggtttt tcaatattgg gctttctgga caagcacttt gcgggtggat
    32881 cgtcagtgtc tgggtggcac ttgcgtttcc agatctgcca aaagttgttt tgcttccgtt
    32941 atgcgtgatc ttaggtgcct tagctggtgc gatggcagcg gctgttccag gtttacttcg
    33001 agcatttttt ggaacaagtg aagtgatcgt aacaatcatg atgaactata tcttattata
    33061 cgtaagcaca tttgctttac atgaagtgat gcctgaaagc tatcgctcaa gtttggactc
    33121 ttccaatatg atcagtcaaa atgcctcact gcggttacca tggttaacac aagcttttgg
    33181 cggctctcgc gtaaactcag gattattttt agcaatcatc gcgcttattt tcgtttggct
    33241 gctgatgaag aaaacgactt taggatttga aatccgttct gttggattga atccttttgc
    33301 ttctgagtat gcaggaatga gtagtaaacg tacgatcgtt ttgtcgatgg tcatttctgg
    33361 cgctttggca gggcttggcg gtgtggttga aggattagga acgtatcaaa acttctttgt
    33421 tcaaacgact tcgctatcta ttggatttga cggaatggct gtttccttgc ttggttctgg
    33481 atcagcaatc ggtattcttt tatcagcgat cttgttcagt attttgaaga tcggtggact
    33541 tggcatgcag acaggagcag gtgttccgtt tgagatcgtc aatgtatcga ttgctttgat
    33601 tatcttcttt gtcgggatca acttcctgat tcgtttcgtc atggctaaag tcttccaagg
    33661 gaaaaaacaa gaagagatcg ttgcgacaat agaatcgaaa ccaacgaatc aaaaccatga
    33721 agggggcgaa ctataatgtc gactatcgaa ttaattgcct tgatccttac ttctacactg
    33781 gtttattcaa caccgctaat tctaacgtca ctaggcggaa ctttttctga acgaagcggg
    33841 atcgtaaacg tagggctaga gggaatcatg gtcatgggtg cttttagttc catcgttttc
    33901 aacttgacga tgagtccatc acttggttct atgacaccat ggatcgctat tttagtgggt
    33961 ggcgtcgtag gtatcctatt ttctctgatt cacgcagtag caacagtcag tttgcgtgct
    34021 gaccatatta tcagcgggac agtaattaat ctgatggcac ctgctttagg tgttttcttg
    34081 atcaaagcat ggtatggtaa aggtcaaact gataacatca cgcagaatct ggggtatttt
    34141 tctttcccag gattagcaga tattccggtc attggaccaa ttttctttaa aaatacattc
    34201 ttacctgctt attgtgctat tttgattgct gtcctagctt gggtgatcat cttcaagacg
    34261 aaattcggct tgcgcctccg ttcagttggt gaaaatcctc aagctgccga cacattaggt
    34321 atcaatgtat atgctatgcg ttattcaggc gtactgattt ctggcttgtt aggcggtatg
    34381 ggcggtgctg tttttgctca gtcgatttcc ggtaactttt cagctggtac gatcgttgga
    34441 caagggttca tctccatggc tgctatgatc tttggtaagt ggaatccttt aggggcaatg
    34501 ggtgcctcat tgttctttgg ttttgctcaa agcttgagta tcattggcgc acaattacca
    34561 gttatttctt cgattccgcc agtattgctg caaattgctc catatttgct gacaatcatt
    34621 gtgctggttg ttttcttagg gaaagcttct ggtccaaaag caaacgggaa gaactatatc
    34681 aaatcaaaat aatcttttag cgaataaaaa gggtgggtta cgggaagtgt ttttcgtctc
    34741 gccctttttg ttttaaaggc aataaaaata aaaagaaaga aggaataatc atgtttaaac
    34801 gcgtacatct gatcgtcatg gattcagtag gaattggaga agcaccagat gccgataagt
    34861 tcggtgatgt tggttctgat acattaggac acattgcgaa agaagcagga ttgaacgttc
    34921 cacatttaga gcagcttggt ttaggaacga tccgtcctct tgaaggtgtg gaatcagtga
    34981 aagatcatca aggctatgcg acgaaattag aagaagtttc tgtagggaaa gatacgatga
    35041 caggccactg ggaaatcatg ggattgaata tcaaaactcc atttcgtgtg tttcctaatg
    35101 gattccctga tgatctgatc aaacaaatcg aagaattttc tggccgtaaa gtcgtatgta
    35161 acaaacctta tagcggaaca gctgttattg acgattacgg tgaacaccaa atgaaaacag
    35221 gcgatttaat tgtatatact tctgccgatc ctgtccttca gatcgcggca catgaagaaa
    35281 tcattccttt agaagaatta tatcggattt gccaattcgt tcgtgatata acaaaagatg
    35341 atccgtatat gattggccga atcattgcac gtccgtacgt gggtgaacca ggagacttca
    35401 cacgaacaag caatcgccat gattatgcgt tgaatccatt cggacacaca gtccttgatt
    35461 ctttgaaaga agcaggaaag gacgtgattg ctgttggaaa gatcaacgat attttcaacg
    35521 gacaaggaat cactgaatct gtccgcacga aaagcaatat ggatggcgtt gaccagctgc
    35581 tgaaagttat gaaaaacgat ttttcaggaa tcagctttac caatttagta gattttgatg
    35641 cattatacgg tcatcgtcgg gatgtagtcg gctatgcgca tgcgattgaa gaatttgact
    35701 tacgaattcc agaattgctt gaagcgatgg aagaagacga cttgctaatg attacagccg
    35761 atcacggaaa cgatccgacg tttactggta ccgatcatac gcgagaatat gtaccgttat
    35821 tggtttacag taaaaaaatg aaagaacaag gggcattgcc tcaaggatat tattcagata
    35881 tttcagcaac gattgctgag aactttagtg tttcttcgac tgaaaatggc gaaagcttct
    35941 tgaaattatt aaaataatct ttttaaatag gagaaagcaa atgaccaagt taagcgagat
    36001 gttacaagaa acgacccagt ttatccttga taaaggagta aaagaaattg attttggttt
    36061 gattctaggt tcaggattag gtgaattagc agatgaaatc gaagatgctg taatgatttc
    36121 ttatgatgag atcccgttct ttcctgtttc gacagtagtt gggcatgcag gaaagctagt
    36181 ttatgggtct ctggcaggca agaaagtgtt agccatgcaa gggagattcc actactatga
    36241 aggtcattcc atgcaaacag tgacctatcc agtacgtgtg atggccggac taggggccca
    36301 ttcagtcatt gtgactaatg catgtggtgg tgtcaacgaa tcatttgtac caggagattt
    36361 gatgctgatt accgatcata tcaattttac tggtgaaaat cctttgatcg gtccgaatga
    36421 agatgcaatg ggccctagat ttccagatat gagtcaagct tatacgcctg actatcaagc
    36481 aacagcaaaa gcagcagcag aaaaactagg tttggatctt aaagaaggcg tatatatggg
    36541 ctattctgga ccaacttatg aaacgcctgc ggagatccga atgtctcgga caataggagc
    36601 cgatgcagta gggatgtcga ctgttccaga agtcatcgta gcagctcaca gcggattaaa
    36661 agtgttagga atctcttgta ttaccaactt agcagcaggt atgcaagcga atctgagcca
    36721 tgaagaagtt gtagaaacaa ctcagagagt caaacaatct tttaaagcat tggttaaaga
    36781 aacattgaca ttattgtaat aggaggaaca ataaaatgag tgtgcatatt gaagcgaaag
    36841 aaggcgagat cgccgataag attttacttc cgggagatcc tttgcgagct aaatatattg
    36901 cggagacttt tttggaagat ccagtttgtt acaatcaggt acgcggtatg ttaggcttta
    36961 ccggcaaata taaaggagaa cgtatttctg ttcaaggaac aggaatggga atgccatcag
    37021 ccaccatcta tgcccatgaa ttgatccagt cgtatggtgt aaagaaattg attcgagtag
    37081 gtacatgcgg tgcattgtca aaagacgtcc atgttcgtga tttagtacta gcacaaggtg
    37141 cagcgaccag ttcttcgatg atcgaaaaaa atttccaagc ctttcatttt cctccaatca
    37201 gtgatttcaa tctattactg aaagcatatg agatagctaa agaaaagggc tatacggttc
    37261 atgtaggaaa tgttctttcg gaagattctt tctacaaaga tgatttgaca gagacgttcc
    37321 aattagctga acttggcgtt ttaggagtgg aaatggaagc agcggctctt tattacttag
    37381 gcgcgaaata ccatgtgcag acattaagtt tgatgaccgt tagcgaccat ttgatcaccg
    37441 gtgaagaaac aacagctgca gaacgtcaat ctacgttcaa tgaaatgatc gaagtaggat
    37501 tggaaacagc gatagcagaa taagaaggaa atgaaaaagc tgccctgcat taagtaataa
    37561 gaacatccaa gcaaaaatag ctcctcatgt ttttgacttg gctggactta ttattgcaaa
    37621 tgtaagcttt tgaacaccgt ttaccaagag gttgtgaatc tgccgtttaa ctctgagtca
    37681 caaggaacaa tttcaaaaaa cagcttttca tgtttgatga atattgtgac ttgtgaccga
    37741 gaagttggca ggagaaaacc gtttatacga aaaaagggac tgtgacaaat cgtgtcacag
    37801 tccctttttt atagtgtttt ttataggtag tattttttag caactgttaa gtcatcattt
    37861 aattcataaa caagtggttg acctgttgga atttcaagat ccatgatgtc ttcgtcagag
    37921 ataccttcga tatgtttagc tagggcgcgt aatgagttac catgtgcagc tactaaaaca
    37981 gttttgttgt ctagtaatgc tggagcaatt tcatcttgcc agaatggcaa agcgcgttct
    38041 aatgtcactt tcaagttttc tccaccagga atatcgcgtt tgtctaacat tgcgtaacga
    38101 cggtcatttg ctgcagaacc ttcgtcagtt tcttccatta atggaggaag agtatcgtaa
    38161 gaacgacgcc agatgtgcac ttgttcgtcg ccgtattttt cagctgtttc ttttttgttc
    38221 aaaccttgta atttaccata gtgacgttcg tttaagcgcc atgatttgat ttgtggtacc
    38281 caaagttgat ctgaatattc taagatcaag ttacatgttt tgattgcacg agttaaaaca
    38341 gaagtgtaag caacatcaaa ttcgattcca gcttctttga ttttgcgtcc gccttctttt
    38401 gcttcttcga ttccttctgg tgctagattt acatcagccc aaccagtaaa ttggttcaat
    38461 gcattccatt cactaagacc gtgacgagaa aaaactaatt ttggcatgtt tagctctcct
    38521 tttaagatag gtttatattt ctgaaatttt cagttctgtt ttattgtaca attttttgga
    38581 agagatttcc atcgaaaaat tagataagat tctatgagaa aacaagtaga gaatataaaa
    38641 aaacgaacag tgcccacgca actgttcgtt tttaggtatt agatgcataa ttgctcgatt
    38701 tctttttcag gtaaattgat atatttataa catgttccaa ctgaaacacc gcattttgaa
    38761 gaaataaatt ggatcgtttc ttttttttca taatagagac gtcggatttt tttgatcgtt
    38821 tttgcatcga tttttggtct tccgccgatt tttccttttt tacgagcttc atctaatcca
    38881 actaatgtac gttctttgat caatgcgcac tccatgtttg ctaggttttc cattaattgg
    38941 aaatagattt ttcccatttc gcgcgtatcg attccttcat caagactaat caagtgcagc
    39001 ccgcgatctt tgaataattg cgtgagttct gttaattgcc gcgtagattt gcctaatcga
    39061 tgaagttggc aaatgactag tgcatcgcct tgttgcatgt cagcgatcac tgactccaaa
    39121 tgaacagcag tagaatcatt ttgttccact tcatatgtct catggaaaat ttcttgacaa
    39181 ccaaagtcag ataattgatc aacctgagtt gttaaatcaa cgtcatttat ggttgtgcgt
    39241 gcataaccaa taattttcat ggtgattcct ttctagcagt gattttctaa ctggatataa
    39301 cagtaaaaat gtagcataaa gtacgtcaaa aagatagttt tttcgcaaat tttccgctgt
    39361 ctttttttat tggatgatca agcagttttt ctttatttac gacggattgc gtcaagaatc
    39421 tcaacgcctt tttctgagcc gacaactact ttagaaacca tgtttaggaa aagcccatgt
    39481 tctactaccc caacaagttc atctaaatag gtagctaagc tttctggctg ttcgatgact
    39541 tctagatgca gatcaatgat gtaatgacca ccatctgtgg ttaagacttc tccgttttcg
    39601 tctgtacgca agacgggttg gaatcttttt tcttcaaaaa tatgaagtag ctgttgggag
    39661 ccataaggga tcacttcaac tgggagtggg aacttcccaa gtttatcgac taatttagaa
    39721 gaatcaacga tccaaatcgt ttcttttgag tacgtagcga ctattttctc gaaaagcaaa
    39781 gcagcgccgc cgcctttgat cccttgaaaa tcagcactga tttcatcagc accgtctatt
    39841 gtcaaatcga ctacggggac ttcatcaata ctctttaacg gtattcctaa tttttccgct
    39901 tgttcttttg tcgcatttga agtagtaact cctgtgatac gtaaaccttc ttcacgcata
    39961 cggcgaccaa tctcttctac catataatag gcggttgaac cggtcccgag acctacgatc
    40021 atcccgtcct ttacgaattt cgcggcttca atgccagcta attgttttaa attcatcttt
    40081 gcgtccacct ttttttagtt tgagcatcgt gctttcctca ctattttagc gtgatttacg
    40141 gtaaaaagat accattcttt tttattccaa taaagctttt tcaaaaaaaa ttgcatctct
    40201 tgttgacatg ttttttcatt cgtgatattc taacaaaggt gctttatcta caggtttctg
    40261 tgaagaaacg tgctgactgt ttatcaaagc atatttgata aggatgcaga cattgcattt
    40321 attttttatc acaaaaaaag aaccacctgg atgtgtggaa ctagacgcaa atcgtgggaa
    40381 ggaggaaaca aggaatgcct acaattaacc aattagtacg taaacctcgt aaatcaaagg
    40441 tggaaaaatc taattcacct gctttgaaca aaggatataa cagctttaag aaaactcaaa
    40501 ctaacgtaaa ctcacctcaa aaacgtgggg tagcaactcg tgtgggtaca atgacaccta
    40561 aaaaaccgaa ctcagcttta cgtaaatatg cacgtgttcg tttgtcaaac ttaattgaag
    40621 ttactgctta tatcccaggg attggtcata acttacaaga acacagtgtt gtattattac
    40681 gcggtggtcg tgtaaaagac ttaccagggg tacgttacca tatcgttcgc ggtgctttag
    40741 atactgctgg tgttaacgac cgtaaacaaa gccgttctaa atacggaact aaaaaaccta
    40801 aagcttaatt ttaattatta aacaaatgaa acttgcttct actatataga agtaattact
    40861 atgaacaata tttcggaagg aggagttacg gatgccacgt aaaggtcctg ttgcaaaacg
    40921 tgatgtttta ccagatccta tttataactc aaaattagta actcgcttga tcaaccgtgt
    40981 aatggttgac ggaaaacgcg ggattgcagc taacattatc tataatgcct ttgacttgat
    41041 caaagaatct acaggtaacg atccattaga agtgtttgaa caagcaatga aaaacgttca
    41101 acctgttctt gaagttaaag cacgtcgtgt tgggggttca aactaccaag taccagttga
    41161 agttcgccct gaacgccgcg ttactctagg tcttcgttgg gtagtaaact acgctcgctt
    41221 gcgcggtgaa cacacaatgg aagaacgctt agcaaaagaa atcatggatg ctgcaaacaa
    41281 cacaggtgct tctgttaaaa aacgtgaaga cactcataaa atggctgatg ccaaccgtgc
    41341 gtttgctcac tatcgctggt aagattctct ctgtttggtc ggcttttata agtcgacctc
    41401 agatagtgtc cttattttta gcaactagat agtaaagaga ggagaaacaa ggagaatgac
    41461 cagagaattt tctttacaaa acactcgtaa tatcggtatc atggcccaca tcgatgctgg
    41521 taaaacgact gctactgaac gtatcttgta ctatactggt aaaatccata aaattggtga
    41581 aactcatgaa ggagcttcac aaatggactg gatggaacaa gaacaagaac gtggtattac
    41641 gatcacttct gctgctacta cagcacaatg gaagggtcac cgaatcaaca tcatcgacac
    41701 accaggacac gtagacttca cagttgaagt tgaacgttca ttgcgtgtac ttgatggtgc
    41761 tgtaactgtt cttgatgcac aatcaggtgt tgaacctcaa actgaaacag tttggcgtca
    41821 agcaacaact tatggtgtac ctcgtatcgt atttgcaaac aaaatggaca agatcggtgc
    41881 tgacttctta tattcagtat caactttaca tgaccgtttg caagcaaacg ctcacccaat
    41941 ccaattacca attggtgcgg aagacgactt cacaggaatt atcgaccttg taacaatgaa
    42001 ggctgaaatg tatacaaacg atcttggaac agagatcgaa gaaacagaaa ttcctgaaga
    42061 ataccgcgaa ttagctgaag aatggcgcga aaaattggtt gaagctgtag ctgaaactga
    42121 tgaagaactt actttgaaat acttagaagg tgaagaaatc actgaagctg agttaaaaga
    42181 aggtatccgc cgcgcaacag ttaacgtaga attctaccca gtactatgtg gttcagcatt
    42241 taagaacaaa ggggttcaat tactattgga cgctgttctt gattacttgc catcaccgtt
    42301 agatatccca gctatcaaag ggattgaccc taaaactgat gaagaagtag aacgtcctgc
    42361 agacgacagc gctcctttct cagctttagc atttaaagtt atgactgacc cattcgtagg
    42421 tcgtttaact ttcttccgtg tgtactctgg tgttttacaa tcaggttcat acgtacaaaa
    42481 cgcaacaaaa ggcaaacgtg aacgtgttgg tcgtatccta cagatgcatg ccaactctcg
    42541 ttcagaaatc tctgaagttt acgctggaga tatcgctgct gctgttggtt tgaaagacac
    42601 aactactggg gacacactat gtgatgaaaa gagtctagtt attcttgaat ccatggaatt
    42661 cccagaacca gttatccaag tcgctattga acctaaatca aaagctgacc aagataaaat
    42721 gggtgtggct ttacaaaaac tatctgaaga agatcctact ttccgtgctg aaacaaacgt
    42781 ggaaacaggc gaaacaatca tcgctggtat gggtgaactt cacttagata tcatcgttga
    42841 ccgtatgcgt cgtgaattca aagttgaagc taacgtaggt gcgcctcaag tatcttaccg
    42901 tgaaactttc cgtgctggca ctcaagccga aggtaagttt gtacgtcagt ctggtggtaa
    42961 aggtcaatac ggtcacgtat ggattgaatt tacaccaaat gaagaaggtg ctggtttcga
    43021 atttgaaaat gcgatcgtcg gtggggttgt tcctcgtgaa tacattccag ctgttgaaac
    43081 tggtttgaaa gatgctatgg aaaatggtgt cttagctggc tatccattag tagatatcaa
    43141 agctaaactt tacgatggtt cataccatga tgtcgattca aatgaaactg ccttccgtgt
    43201 tgctgcttct atggcattac gtgcagcagc taagaaagct aatccagtaa tccttgaacc
    43261 aatcatggct gtagaagttg ttatccctga agattattta ggtgatgtta tgggtcacgt
    43321 aactgctcgt cgtggacgtg ttgaaggtat ggaagctcgc gctggcggcc aacaagttgt
    43381 tcgtgcgatg gttccacttg ctgaaatgtt tggttatgct acaactcttc gttctgctac
    43441 tcaaggtcgt ggtacattta caatgacatt tgaccactac gaagatgtac caaaatcagt
    43501 acaagaagaa atcattaaga aaaacggcgg aaaagctgaa taatttctta aaaccggata
    43561 gtcctgcaaa gagattatcc aaagagacta tatttttaat atagtttcgt gtaaaataat
    43621 tatcgatgat atgggcatgt ggtgtacctt gtgtacatca tatacctatc agacaaataa
    43681 aaaatatatt gtatttttag gaggacattt taaaatggca aaagaaaaat ttgaccgttc
    43741 taaaccacac gttaacattg gtactatcgg acacgttgac catggtaaaa ctacattaac
    43801 agctgcaatc acaactgtac tatctaagaa aaacggcggc caagctatgg cttacgatca
    43861 aatcgatggt gctccagaag aacgcgaacg cggaatcaca atctcaacag ctcacgttga
    43921 gtatgaaaca gatacacgcc actacgctca cgttgactgc ccaggacacg cggattacgt
    43981 taaaaacatg atcactggtg ctgctcaaat ggacggagct atcttggtag tttctgctgc
    44041 tgacggccca atgcctcaaa ctcgtgaaca catcctattg tctcgtcaag ttggtgttcc
    44101 ttacatcgtt gtattcttga acaaagtaga catggttgat gacgaagaat tactagaatt
    44161 agttgaaatg gaagttcgtg acctattaac agaatacgaa ttccctggtg acgatgttcc
    44221 tgtagttgct ggatcagctt tgaaagctct agaaggcgac gcttcatacg aagaaaaaat
    44281 tcttgaatta atggctgcag ttgacgaata catcccaact ccagaacgtg acaacgacaa
    44341 accattcatg atgccagttg aagacgtgtt ctcaattact ggacgtggta ctgttgctac
    44401 aggtcgtgtt gaacgtggac aagttcgcgt tggtgacgaa gttgaagttg ttggtattgc
    44461 tgaagaaact tcaaaaacaa cagttactgg tgttgaaatg ttccgtaaat tgttagacta
    44521 cgctgaagct ggagacaaca ttggtgcttt actacgtggt gttgcacgtg aagacatcca
    44581 acgtggacaa gttttagcta aaccaggtac aatcacacct catacaaaat tctctgcaga
    44641 agtatacgtg ttgacaaaag aagaaggtgg acgtcatact ccattcttca ctaactaccg
    44701 tccacaattc tacttccgta caactgacgt aacaggtgtt gttgaattac cagaaggaac
    44761 tgaaatggtt atgcctggcg acaacgtaac aatggaagtt gaattaatcc acccaatcgc
    44821 tatcgaaaac ggtactaaat tctcaatccg tgaaggcgga cgtacagttg gtgccggtgt
    44881 cgttacagaa atcaaagctt aattcactta agttttaaag taaagcaaca tttattcgga
    44941 cgtaatcgct cggaacgaag gtcttaggat ctttgttccg agctttttta tttattgcag
    45001 gatcaggaaa aaagacagga gtattataaa tagaagaaac acgaaataaa agagtcagta
    45061 ttttctaaat gaaactttat gaaaacaaaa tgttttttac aagaaaaagc cttgctttgt
    45121 gagtttatat atattataat gacaaaggtg cgtttacttt agtgaattgc acagacgtaa
    45181 tcagaatgat ttcgtcggct aagaaacgag aggttgcgac acgcccggac gctttgccac
    45241 gaacgagcgt gacggaaatt ttcgtggagc tatgtctact tttcaaaata ggcgaaggag
    45301 ggaacaagat ggcaaaacaa aaaattcgta tccgtttaaa agcgtatgaa caccgtattt
    45361 tagatcaatc agcggataaa atcgtggaaa ctgcaaaaag aactggagct agcgtgtctg
    45421 gtccaattcc attaccaact gaacgcagtc tttacacaat catccgtgcg actcataaat
    45481 acaaagattc acgcgaacaa ttcgaaatgc gtacacacaa acgtcttatc gacattgtga
    45541 acccaacacc aaaaactgtt gatgctttga tgaagctaga cttaccatct ggtgtaaaca
    45601 tcgaaatcaa attataaaac taaaacaaaa ataatggagg tgtactcatg accaaaggaa
    45661 tcttagggaa aaaagtggga atgacacaaa tcttcactga atctggtgaa ttaattccag
    45721 taactgttgt agaagctact ccaaacgtag tactacaagt gaaaacaatg gaaacggatg
    45781 gctacgaagc tattcaagtt ggttaccaag atatgcgtga agttttatca aacaaacctg
    45841 cgaaaggtca tgttgcaaaa gcaaacacgg ctcctaagcg cttcattcgt gaattcaaaa
    45901 atgttgagct aggagaatat gaagtaggaa aagaaattac agtagatgtt ttccaagcag
    45961 gagacattat tgatgtaaca ggtactacga aaggtaaagg attccaaggg gttatcaaac
    46021 gccacggaca aagccgcgga ccaatggctc acggttctcg ttaccatcgt cgtcctgggt
    46081 caatgggtcc agttgcacct aaccgtgtat ttaaaaacaa acgtcttgct ggccgtatgg
    46141 gtggcaaccg cgtaactatc caaaacttgg aagttgtacg tgtcgatgca gaaagaaatg
    46201 ttatcttgat caaaggtaat gttcctggag ctaaaaaatc tttaattact atcaaatcag
    46261 ctgtgaaagc taaataattg taggaagaaa ggaggaacta aggaatgccg aatgtagcat
    46321 tattcaaaca agatggaagc caaaacggtg aaatcacact taacgaagaa atcttcggaa
    46381 ttgaacctaa tgaaagtgtt gtttacgatg caatcgtaat gcaacgtgcg tcattaagac
    46441 aaggaacaca cgcggttaaa aaccgtagcg ctgttcgcgg cggcggacgt aaaccatggc
    46501 gtcaaaaagg aacaggtcgt gcacgtcaag gatctatccg ctcaccacaa tggcgtggag
    46561 gtggcgtagt ctttggacca acaccacgtt cttacagcta caaacttcct aaaaaagttc
    46621 gtcgtttagc aatgaaatct gtattgtcag aaaaagttgc tgaaaacaac ttggtagcaa
    46681 tcgaaggctt gaacttcgac gcaccaaaaa caaaagaatt caaacaagtt cttgctaact
    46741 tatctatcga ctctaaagta ttggttgttc tagaaaaagg taacgacttt gctgctttat
    46801 cagcacgtaa cttaccaaac gtttctgtag taacttctga taatgtgagt gtgctagacg
    46861 ttgtatcaaa tacaaaagtg ttagcaacac aaactgctct tactcaaatt gaggaggtgc
    46921 ttgcataatg aacttactag acgtaatcaa acgcccagtg atcactgaaa aatcaatgct
    46981 tgccatggat gacaagaaat acacttttga agtggacact cgcgcaaaca aaactttagt
    47041 aaaacaagcg gtagaagctg cttttgacgt taaagtcaaa aacgtgaaca tcgtgaacgt
    47101 acgtgcgaaa ttcaaacgta tgggcaaata tgcaggatat acaaaaaaac gtcgcaaagc
    47161 gatcgttaca ttgactgaag attcaaaaga aatccaatta ttcgaagctg ctgaataagc
    47221 actaatagat aactcattaa attaggaggg aaaaacgtgg cgattaaaaa gtacaaacct
    47281 acctcaaatg gtcgtcgtaa catgacaggt tctgattttg ctgaaatcac aacatcaaca
    47341 cctgaaaaat cattgttaca accattgaaa aaccatgctg gacgtaacaa caacggccgc
    47401 atcactgtac gtcatcaagg tggcggacac aaacgccaat atcgcgtgat cgacttcaaa
    47461 cgtaacaaag ataacgttgt tgcaactgtt caaacgatcg aatatgatcc aaaccgttca
    47521 gctaacatcg cgttagtaca ctatgaagat ggagtgaaag cttacatctt agcacctaaa
    47581 ggactagaag tgggtatgaa acttgtttca ggtccagaag cagatatcaa agtcggaaat
    47641 gctcttccat tagaaaacat tccagttggt actgttatcc acaacattga aatgaaacct
    47701 ggtaaaggtg gacaattgat ccgttctgct ggtacaagtg ctcaagtact tggtaaagaa
    47761 ggcaaatacg tattgatccg cttgaactct ggtgaagttc gtatgatctt agctgcatgc
    47821 cgtgctacaa tcggttctgt aggtaacgaa caacacgaat taatcaacat cggtaaagct
    47881 ggacgctctc gttggatgcg taaacgccca actgtacgtg gtagcgtaat gaaccctaat
    47941 gatcacccac acggtggtgg tgaaggtaaa gctcctatcg gacgtaaagc accagtttct
    48001 ccttggggtc aaccagctct tggttacaaa actcgtaaca aaaaagctaa atcagacaaa
    48061 cttattgttc gtcgtcgcaa aaataaataa ttactttgac catgtgtcgc acattttgag
    48121 aggaggttca ccatgggtcg tagtttaaag aaaggacctt ttgtcgatga gcatttaatg
    48181 aaaaaagttg aagctcaagc aggggttgaa aagaaaaaag ttatcaaaac ttggtcacgc
    48241 cgttcaacag ttttcccaag ttttgttgga tataccatcg cagtttatga tggacgtaaa
    48301 catgtaccag tttacatcca agaagacatg gtaggacaca aattaggtga atttgcacct
    48361 acaagaactt atcgtggaca tgctgctgac gataagaaaa cgaaacgcta atttgagggg
    48421 aggataaatc caaatggcag aacaaatcac atcagctaaa gcaactgcaa aaacagttcg
    48481 cacttcacct cgaaaagccc gtttagtaat tgaccttatc agaggtaaaa gtgtcgcaga
    48541 tgcaatttca atcttgaaat tcacaccaaa caaatctgct ggaatcattg aaaaagtatt
    48601 gatgtcagca gttgcgaatg cagaaaataa ctttgactta gatgttgaaa acttggtagt
    48661 aagcgaagct tttgttaacg aaggacctac aatgaaacgt ttccgtcctc gtgcaaaagg
    48721 atcagcttct ccaatcaaca aacgtacaag tcatatcacg gtagtcgtat cagaaaaata
    48781 aggagggata atcagtgggt caaaaagtac atccaattgg aatgcgtgta ggcatcatcc
    48841 gcgactggga tgctaaatgg tatgctgaaa aagagtatgc tgagttctta cacgaagatt
    48901 taagaatccg taaatttatt tcaactaaac ttgctgatgc tgctgtatca acagttgaaa
    48961 tcgaacgcgc aacaggtcgc gtaaacattt caattcacac agctaaacca ggtatggtta
    49021 ttggtaaagg cggttctgaa gtcgaaagcc taagaaaaga attaaacaaa ttaactggta
    49081 aaagaatcca tatcaatatc gtggaaatca aaaaaccaga tctagatgca aaattagtag
    49141 gtgaaggaat cgcacgtcaa ttagaaaacc gtgttgcttt ccgtcgcgct caaaaacaag
    49201 ccatccaacg ctcaatgcgt gctggcgctc aagggatcaa aactcaagta tctggtcgtc
    49261 taaacggagc agatatcgct cgttcagaag gatactcaga aggaactgtt cctcttcata
    49321 ctttacgtgc ggacattgat tacgcatggg aagaagcaga tacaacatac ggaaaactag
    49381 gagttaaagt gtggatctat cgtggagaaa ttcttccaac taaaaaaaac actgagaaag
    49441 gagggaaata atcatgttag tacctaaacg tgtaaaacac cgtcgtgaat tccgcggaaa
    49501 aatgcgcggg gaagctaaag gcggaaaaga agtagcattc ggtgaatacg gtttgcaagc
    49561 tgttgattca cattggatca caaaccgcca aatcgaagct gctcgtatcg caatgactcg
    49621 ttacatgaaa cgtggtggga aagtatggat taaaattttc cctcacaaat cttatactgc
    49681 caaagcaatt ggggtacgta tgggttctgg taaaggggca cctgaaggat gggttgcacc
    49741 agtaaaacgt ggtaaaatca tgtttgaaat cgcaggcgtt cctgaagaag tagctcgtga
    49801 agcgttacgt ctagcttctc acaaattacc aatgaaaact aagatcgtaa aacgtgagga
    49861 aatgggtggt gaatcgaatg aaggttaaag aaatcagaga attaaccact gccgaaatgc
    49921 ttgatcaaga aaaacaatta aaagaagaat tgtttaatct tagattccaa ttagcaacag
    49981 gtcaattaga aaacactgca cgtattaaag aagtacgtaa atcgattgca cgcatcaaaa
    50041 ctgtgttgcg tgaacaagct aagtaattat ggaaggaggc cattaagcgt atgactgaag
    50101 gaagaaatca acgcaaagtt tatcaaggtc gcgtggtttc agacaaaatg gataaaacaa
    50161 ttaccgttgc tgtcgaaaca aagaaaaacc accctatcta tggcaaacgc atgaactatt
    50221 ctaagaaata caaagtgcat gatgaaaaca acacagcaaa agttggcgac atcgtgagaa
    50281 ttatggaaac tcgtccatta tcagctacaa aacgtttccg tttgttggaa gtagtcgaag
    50341 aagcagttat tatctaataa cacgagattt tcctatatag attgaatgca aaatctgaaa
    50401 ggaggataca caacgtgatc caagcagaaa gtcgtttaaa agtcgctgat aactcaggcg
    50461 cacgtgaaat tttgacgatc aaagtccttg gtggatctgg tcgtaaaact gctaacatcg
    50521 gtgatgtgat cgttgctacg gttaaacaag caacgccagg tggggttgtc aaaaaaggtg
    50581 acgtcgttaa agccgttatc gttcgaacaa aatcaggagc tcgtcgtaca gacggttcat
    50641 atattaaatt tgatgaaaat gctgcagtga ttattcgtga tgataaaagc cctcgtggaa
    50701 cacgtatctt tgggccagtt gcacgtgaac tacgtgaaaa caacttcatg aagatcgttt
    50761 cactagcacc agaagtttta taatcttgag acacttatca aaggaggtgc gaaacagtta
    50821 tgtttgttaa aaaaggcgat aaagttaaag ttatcactgg aaaagacaaa aacaaagaag
    50881 gcgttgtact agcagcgttc ccgaaaaaag ataaagttat tgtcgaaggt gtaaatgtcg
    50941 ttaaaaaaca ccaaaaacct tctcaagctg ctcctcaagg tggaattgtt gagatggaag
    51001 cgccaattca tgtttctaac gtgatggtgg ttgactctac tggtgtagct ggccgagttg
    51061 gctacaaaga agtagacggc aaaaaagtcc gtgtttctaa aaaaaccggt gaagttttag
    51121 ataaataaaa gtttaaggaa ggagggtctt actgaatgaa ccgcctaaaa gaaaaatatc
    51181 ttaaagaagt aactccatca ttgatggaaa aatttaacta tagctctgtt atgcaaacac
    51241 ctaaagttga aaaaatcgtc atcaacatgg gtgttggtga tgcggtatca aacgctaaaa
    51301 acttagataa agcagttgaa gaattaactt tgatcactgg tcaaaaacca atgattacaa
    51361 aagctaaaaa atcaatcgct ggattccgtt tacgtgaagg aatgccaatt ggtgcaaaag
    51421 ttacattgcg cggagaaaga atgtacgaat tcttagacaa attggtttct gtttcactac
    51481 cacgtgtacg tgacttccat ggtgtaagta aaaaagcctt tgacggtcgt ggaaactata
    51541 ctttaggtat taaagaacaa ttgatcttcc cagaagtaga ttatgattta gtagataaag
    51601 tacgtggtat ggacatcgtt attgtaacaa cagcaaactc tgatgaagaa tctcgtgagt
    51661 tgttgacaca attaggcatg ccattccaaa aataattaaa ggaggcgaac tacgtggcta
    51721 aaaaatcaat gattgctaaa aacaaacgtc ctgcaaaatt ttcaacacaa gcttatactc
    51781 gttgcgaacg ttgcggacgt ccacattcag tttatcgtaa gttccatctt tgccgtattt
    51841 gcttccgcga acttgcctat aaaggtcaaa ttcccggcgt gaagaaagct agctggtaaa
    51901 aagtaaattc gcataagaag gaggtaaaag atcaatggtc atgacagatc caattgcaga
    51961 ttttctaact cgtatccgta acgcaaacat ggttaaacat gagtctttag aagtacctgc
    52021 atcaaaaatt aaacgtgaca tcgctgaaat cttgaaacgt gaaggtttcg ttcgtgatgt
    52081 tgaatacatc gaagatgaca aacaaggcgt gatccgtgtt ttcctaaaat ttggtaaaaa
    52141 cggcgaacgt gttatcacaa acttaaaacg tatctctaaa ccaggtttgc gtgcttatgt
    52201 caaagctgac gaagtaccaa aagtattgaa cggtttaggt atcgcaatca tttcgacttc
    52261 tgaaggtgtt gtcactgata aagaagctcg tgaaaaaaat atcggcggcg aagttatcgc
    52321 ttacgtatgg taatcaagta gaatctacaa ggaggtgtct ttaagtgagc cgtatcggaa
    52381 ataaagtcgt tgttatccct gaaggagtaa cagttactca agacggaaac aacgttacag
    52441 ttaaaggacc aaaaggtgaa ttgactcgta ctttttcagc agatatcaaa atgaatatcg
    52501 aaggaaacga agtaactttc actcgtccaa acgacagtaa agaaatgaaa acaattcatg
    52561 gaacaactcg tgcgaacttc aacaacatgg ttgtaggtgt cagcgaaggt ttccaaaaag
    52621 cgttagaact aatcggggtt gggtaccgtg cacaattaca aggatcaaaa cttgtattga
    52681 acgttggtta ctcacatcca gtagaaatca caccaccagc tggagtaact gttgaagtac
    52741 cagctaacac acaagtaatt gttaaaggtg cgaacaaaga agaagttggc gaattagctg
    52801 caaacattcg tggaactcgt cctccagaac cttataaagg taaaggtatt cgttatgttg
    52861 gcgaatatgt acgccgtaaa gaaggtaaaa ctggtaaata atcgtttaga aaaattgcat
    52921 agaagccagc agcaggaaaa aggcatttgg ctgaagttta ccttcaaaaa aatacatttt
    52981 tacttgtgcc gcagcttcta tttttcgaaa cgtatttact gcttgaaata gtagtacaat
    53041 aaaaataaag aggtgacaat tgtgattaca aaaccagata agaacaaaac acgtcaaaag
    53101 agacatcgtc gtgtacgtaa caatatctct ggtactgctg agcgcccacg cttgaacgtt
    53161 tttcgttcta acaaaaacat ctacgctcaa attattgatg acgtagcggg tgtaacgcta
    53221 gcaagtgcct ctaccttgga taaagaaatt tcaggtggaa caaaaacaga agcagcacaa
    53281 gctgtcggta aactagttgc tgaacgtgca gctgaaaaag gcattaaagt agtagtcttt
    53341 gaccgtggtg gataccttta ccatggccgt gtgcaagctt tagctgaagc tgctcgcgaa
    53401 aatggactag aattttagaa gaaggaggaa taccattcat ggtttatatc gatccaaaac
    53461 atttggaatt agaagaccgc gttgttgcaa ttaaccgtgt aacaaaagtt gttaaaggtg
    53521 gacgtcgtct acgttttgct gctttagttg ttgtcggtga caaaaacgga cacgtagggt
    53581 ttggtacagg taaagctcaa gaagttcctg aagcaatccg taaagcaatt gaagatgcga
    53641 agaaaaactt agttgaagta cctatggttg gttcaacaat cccacacgaa gtaatcggtg
    53701 cttttagtgg tggtagaatc ctaatgaaac ctgctgtaga aggttctggg gttgctgctg
    53761 gtggaccagt tcgtgccgta ttagaattag ctggggtagc agatatcact tctaaatctt
    53821 taggctcaaa tacaccaatc aacgttgttc gcgcaacagt tgaaggtttg aaacaattga
    53881 aacgtgcaga agaagttgca gaacttcgcg gcaaatcagt tgaagaatta atcggataag
    53941 gaggacaaca ataatggctg aattaaaagt tactttaaaa cgcagtatta tcggacgtcc
    54001 tcaaaaccaa cgcgatacag ttaaagcgtt aggtcttaca aagattaaca gttcagtggt
    54061 taagccttct aatgaagcaa ttaaaggcat gatcaatact gtttctcacc tagtggacgt
    54121 tgaagaaatt taatttagaa aaatcataac tagaacatta aggaggtgcc aaacctatga
    54181 aacttcatga attaaaacct gctgaaggtt cacgccaagt acgtaaccgt gttggtcgtg
    54241 gtacttcatc tggtaacgga aaaactgccg gacgcggaca aaaaggacaa aaagctcgtt
    54301 caggcggcgg tgtgcgttta ggatttgaag ggggacaaac accattgttc cgtcgtttac
    54361 caaaacgagg attcacaaac gtgaaccgta aagactatgc agtcattaat cttgatgtat
    54421 tgaaccgctt tgaagacgga gctgaagtaa ctcctgttgc tttagttgaa gctggaatcg
    54481 tgaaaaacga aaaagctgga atcaaagtat tagctaatgg ggaactaaac aagaaattaa
    54541 ctgtgaaagc agcaaaattc tctaaagcag ctcaagaagc aattgaagcg gctggtggat
    54601 caatcgaggt gatctaatgt ttagactatt aaaagatgct tttaaagtaa aagacattag
    54661 atcgaaaatc ctatttactg tatttgtgtt gtttgtattt cgcctaggtg cacatattac
    54721 tgtaccaggc gtaaatgctg cttcattgca aaacctttct tctttgccat ttttcaacat
    54781 gttgaacttg gtaagtggta gtgcgatgca aaacttttcc attttctcaa tgggggtttc
    54841 accatacatt actgcttcta tcgtcattca gcttcttcaa atggacatcg tgcctcgatt
    54901 tgttgaatgg tcgaaacaag gggaagttgg tcgtaaaaaa ctgaatcaag cgactcgata
    54961 tctgacatta gtattggcat ttatccaatc tgtcggtatc actgctggat tcaatcaata
    55021 cgctcaatta ggtttcgtga ataatcctaa cgtagcaact tacgtaacga tcggtttgat
    55081 tctaacagcc ggtacgatgt ttgttacttg gctaggagaa cagatcacag aaaaaggtat
    55141 cggaaatggc gtatcaatga tcatttttgc aggtatcatt tctagattgc ctgaaagtat
    55201 cagagaaatt tatgaagatt actttataaa tattgatcct tcagacatat ggaaatctgc
    55261 tatttttgtg gccattttac tagtagcggt cttgttgatc gtgacattcg taacattttt
    55321 ccaacaagct gaacgcaaga tcccgatcca atatacgaaa cgcgtagctg gcgcgcctac
    55381 aagcagctat ctgccgttga aagtaaatgc agctggagtt attccagtta tctttgctag
    55441 ttcgtttatt gctacgccaa atgctgtttt acaagcattg agcggtagat tcggttctga
    55501 aaactggtac aaagtgatga tggagatctt taactataat acagcacctg gtgctacgat
    55561 ttatacgatt ctgatcgttg ccttcacttt cttctacgcc tttgttcaag taaaccctga
    55621 gaaattagcg gaaaacttgc aaaagcaagg aagttatata ccaagcgtac gccctggtaa
    55681 ggggactgaa gagtatgtct caagattact gatgcgttta agtacagttg gtgcagtctt
    55741 ccttggttta gtggcattgc ttccaatcat tgctcaaatg gtttgggatc ttccacaatc
    55801 aatcggatta ggcggtacaa gcttactgat cgttatcggt gtagctttag aaactgcgaa
    55861 acagttagaa ggcttaatgc tgaaacgtaa atatgttgga ttcattgagt aagaaagcgt
    55921 gttgaggttt cccctcaaca cacgttctca cacatttatt aggagggaaa acaatgaacc
    55981 tcattttaat ggggctgcca ggcgcaggta aaggaacaca agctgaaaaa atcattgatg
    56041 cttatggtat tccgcacatc tcaacaggag atatgttccg cgcagcgatg caaaacgaaa
    56101 cagctcttgg cctggaagca aagtcttata tggataaagg tgcattagtt cctgatgaag
    56161 taacaaatgg aatcgtgaaa gagcgactag ctgaaccaga tacagagaaa ggcttcttat
    56221 tagatggctt tccacgtacg ctagatcaag caaaagctct ggacgcaatg ctaaaagatt
    56281 tgaataaaaa aattgatgct gtcatcgata tccatgttgg tgaagaaatc ttggtcgaac
    56341 gtctagccgg ccgatttatc tgcagcaatt gtggagcaac ttaccataaa attttcaacc
    56401 ctacaaaagt tgaagacaca tgtgatcgtt gcggtgggca tgaattctat caaagagaag
    56461 atgataaacc tgagacggtt aaaaatcgtc tggctatcaa catcaaaaat agtgaaccaa
    56521 tcttggctta ttataaagaa caaggtttgc taaacactat tgatggtgct cgtgaaatcg
    56581 atgctgtatt tgcagatgta caaaaaatca ttgaaaaata gcacgattgc ccgtagccga
    56641 cttgcattat gcagttactc ttgtcaagtt caataaatta tgatagaata tgtcagtccg
    56701 acttctagag aatcctctag atgatccatt ttgagaattt tgaggtggga actgcagttt
    56761 ccgccatttt atcgtgtgaa aatgcgaaac aagtacaagg aggtactgtg cgtggcaaaa
    56821 gaagatatga ttgaagtcga aggtacagtc gtcgaaactt tgccgaatgc aatgtttaaa
    56881 gttgaactag aaaacggaca ccaagttctt gctactgttt caggtaaaat tcgtatgcat
    56941 tacatccgta tcttacctgg tgacaaagta acggttgaat tgtctccata cgatcttaac
    57001 cgtggccgta ttacttatcg ctttaaataa ttgtactccg taaaactaca ggaggtatta
    57061 tcatgaaagt aagaccatca gtaaaaccaa tgtgcgaaca ttgtaaagta attcgtcgta
    57121 aaggacgcgt tatggtgatt tgcccagcaa atccaaaaca taaacaacgt caaggataat
    57181 tggaggtgct ataaatatgg ctcgtattgc aggagtagat attcctcgtg ataaacgtgt
    57241 agtagtttca cttacttata tctatggtat tggtaacact actgctaaaa agatcttagc
    57301 tgatgctggt gtatctgaag atgttcgcgt tcgtgaatta acgaatgaac aaacagatgc
    57361 tatccgtgca gaagtagata aattaaaagt tgaaggggat cttcgtcgtg aagtgaactt
    57421 gaacatcaaa cgtttgatgg aaatcggttc ttaccgtgga atccgtcatc gccgtggatt
    57481 gcctgttcgt ggacaaaaca cgaaaaacaa tgcacgtact cgtaaaggcc cagctcgcgc
    57541 tatcgctggc aagaaaaaat aattcttaag tgaaggaggt taaaacttca tggcagcaaa
    57601 aaaagtgaat cgtaaacgcc gtgtgaagaa gaatatagaa gcaggtattg cacatatcca
    57661 ttctacattc aataacacta tcatcatgat cactgatact cacggaaatg cattagcgtg
    57721 gtcatcagct ggttcattag gtttcaaagg aagcaaaaaa tcaactcctt ttgccgctca
    57781 aatggcagca gaaactgcta caaaagcagc aatggaacac ggattaaaga ctgttgaagt
    57841 aacagttaaa ggacctggtt ctggacgtga agcagcaatt cgttcattac aagctacagg
    57901 tttagaagtg actgcaattc gtgacgtgac tccagttcct cataatggtg cccgccctcc
    57961 aaaacgccgt cgtgtttaat gagtgccgct cattttgagt tttatcagta acgtcattga
    58021 acaagacact tttcgttttg aaaggggtaa agataagaat gattgagttc gaaaaaccaa
    58081 gaatcgcaaa aattgatgaa gaaaaagatt atggcaagtt catcgttgaa cctcttgaaa
    58141 gagggtatgg gactacttta gggaattccc tacgtcgtat tttattatct tctttgccag
    58201 gtgctgccat cactaatatt caaatcgatg gtgtactgca tgaattctct accatcaaag
    58261 gtgttagaga agacgtcact caaatcatct tgaacattaa aggcttagcg ctgaaaatgt
    58321 atggccaaga agaaaaaacc cttgaaatcg atattaccgg acctgctaca gtaactgctg
    58381 gcgatattat cgttgatagt gatgtagaaa ttcttaacaa agatatgtac atctgtagtg
    58441 tctctgaagg agctacgttc catgctcgct taacagtgaa acctggacgt ggttatgttc
    58501 aagcagatga aaataaaaaa gaagatatgc caattggcgt tcttccagtc gattcaatct
    58561 acacacctgt tcgtcgtgtg aactatcaag ttgagaacac acgtgttgga caccgtgaag
    58621 attttgataa attgacgatg gagatttgga cagatggttc aattgaaccg ttggaagcaa
    58681 tgagtttgtc tgcgaaaatc atgactgaac atttggatat ttttgtgaac ttaactgatg
    58741 aagcaaaaaa tgctgaaatc atggtcgaaa aagaagaaac acaaaaagaa aaaatgttgg
    58801 aaatgacgat cgaagagtta gacttgtctg ttcgctctta caattgtttg aaacgtgcag
    58861 gaatcaatac tgtacaagaa cttacaaata aatctgagcc tgaaatgatc aaagtccgta
    58921 acttaggacg taaatcatta gaagaagtta aagcaaaatt gcacgactta ggtttaggtt
    58981 tacgtaaaga agattaaaac cttttacgaa ggagggaaac caacgtgagt tatcgtaaac
    59041 taggacgcac atctagccaa cgtaaagcga tgttgcgtga tttaacaact gatttattaa
    59101 tcaacgaacg tattgtgact actgaagctc gtgcgaaaga agttcgctca actgcagaaa
    59161 aaatgatcac tttaggtaaa cgcggagatt tgcatgcacg tcgtcaagct gcggctttcg
    59221 tacgtaatga agttgccagc gtgcgtgaag aaaatgagga catcgtcatt gaatcagctt
    59281 tacaaaaact gttcaacgat attgcacctc gttacgcaga acgtcaaggc ggatacacac
    59341 gcattttgaa gacagaacca agacgcggtg atggtgcacc aatggttgtc ttagaacttg
    59401 tctaaaatca cactaataac atcactttat agatgattct tttagagtgt tatgatgttg
    59461 gaagatattt ttccgagtct agctcagcgc tgctcctcaa gcgaatatcg cttggggagt
    59521 aagcactcat cataaagtgt ttttttatac cttcaattac ctgtcatgac agatatgttt
    59581 gaaggcataa aaaaacattt taagcgagaa ataattgaaa attttgtctt tttttgatag
    59641 tgttagtagg aactttagga tgaagaagga gtaatcatgg agccaattat tgaattagaa
    59701 aagataaatt ataaatacca gccagatgat cttcgccccg cattgaaaga tgtctccttt
    59761 acaattgata aaggtgagtg gatcgctatt attggacaca atggttcagg aaaatcgaca
    59821 cttgccaaaa cgatcaatgg attgcttctg ccagaatcag ggatcgtgaa agtgggaaat
    59881 caaatattgg atgaagaaaa tatttggacg atccgacaga tggttggaat ggtttttcaa
    59941 aatccagaca atcagtttgt tggttcgaca gtagaagatg acgttgcttt tggtcttgaa
    60001 aatcaaggga ttcccagaga agaaatgcta gtgcgtgtga aagatgcact tgagaaagtt
    60061 agaatggctg agtttgcttc acgcgagcct gctcgtttat caggagggca aaaacaacgt
    60121 gttgccattg ccggcgtggt tgccttacga cctgatatca ttattttaga tgaagcaacc
    60181 agtatgctag atccagaagg tcgtgaagaa gtgatctcta cgatcaagaa gatcaaagaa
    60241 gaaagtcaat tgaccgttat atctatcact catgatattg atgaagcagc taatgccaat
    60301 cggatactag tgatgagaca aggcgaactt gtccgtgaag gtacaccaaa agaaattttt
    60361 tctgctggtc ctgaactgat cgacttaggt ctagatctac catttcctga aaaactgaag
    60421 agcgcactga aagaacgtgg ggttgatgtg cccagtgaat atatgacaga agaaaggatg
    60481 gtggattggt tatggacatc cgttttgaac aagtagactt cacttatcag ccgaatacac
    60541 catttgaaca aagagcctta tttgacatca atatgacgat caaagaaaac agttatactg
    60601 cattagtagg gcataccgga agcgggaaat caaccttact tcagcatttg aatgcgcttg
    60661 ttaagccaac aagcggtaca gtccatattg gagaacgaga tattcagccg gatacggata
    60721 ataagaattt aaagcccatc cgaaaaaaag ttggcatcgt ctttcagttt ccagaagcac
    60781 agctattcga agaaacggta gcaaaagaca ttgctttcgg tcctaaaaac tttggtgtca
    60841 gcgaagaaga agcactagtc ctagcaaaag aaacattaga acaagttggg ctggatgaaa
    60901 gctatttgga acgttcgcca tttgaacttt caggagggca aatgcgtaga gtagcaatcg
    60961 ctggtgtgct tgccatgagg ccggaagtac ttgtattgga tgaaccaacg gcaggacttg
    61021 atccccaggg tagaaaagaa atgatggaga tgttttggcg tcttcataag gaacagcaga
    61081 tcactattgt attagttacg catttaatgg atgatgtagc caattttgca gattatgtct
    61141 atgtgttgga aaagggacga atcgttaata gcggggagcc gcaagaggtc tttcaaaaca
    61201 ttgaatggct aaaagaaaaa caactaggcg tacctactgc caccgagttt gcagaagaat
    61261 taatggctaa agggatgaac tttgctacct tgcctttgac agctgaagaa ttagcagacg
    61321 ctatcgtcca ttatgctgga ggaaatgccc atgatgaata aattgatatt tggtcgttat
    61381 atgcctggag attccttgat ccatcgattg gatccccgag ctaaattatt agccagtttt
    61441 tattttatcg gaatcatttt tttagcaaat aattgggaaa cgtacctttt gttggcattt
    61501 ttcacattac tttctgtctt cttgtcaaaa gtagatttga aattttttat ccgaggcatt
    61561 cgcccattga tctggctaat cctcttcact gtagctttgc aggtcttgtt tacaagtggc
    61621 ggagaaactt attggagttg gggtgttttc catatcactg aatttggtgt gatgaacggc
    61681 ctctttattt tctgtcgatt cgtgttgatc atttttatgt cgactctact cacgcttact
    61741 acaccgcctt tggaattatc ggatgcgatt gagtacttgc ttcgtccatt gaaagccgta
    61801 cggttcccag tccacgaaat ttcattgatg ctgtcgattg ctcttcgttt tgtgcctaca
    61861 ttgatggacg aaacagaaaa gatcatgaac gctcagcgcg ctcgcggtgt tgattttggt
    61921 gaaggaaacc tagttcagaa aatgaaagca gtcattcctt tgctgattcc tttatttgtc
    61981 agcagcttca accgtgcgga agatcttgcg actgctatgg aagcaagagg ctacaaaggt
    62041 ggggaaggaa gaacgaaata tcgtgtattg cattggcata atagagacac gatggttatc
    62101 attgcttttg tattattaac tgtgctactg atctttttga gaggataaac gttcagtggg
    62161 ccgctatcta ttcttttctt gctgatctgt ttgcaagaaa ggatgcgagc agtgtatgac
    62221 aagaaatatt agggtctgtg gcagactaag gtcacaggcc tctttctttt atctgaaaag
    62281 aaagaacgaa aaaattttat aaaaaaatca ttattccaga taacctttta ggaacaaagg
    62341 agagaaaaac atggtacgtt acaaagcaat cattgcatac gacggaacaa attttaatgg
    62401 attccaaaaa cagccaaatg ggcgtactgt tcaagaagaa gtagaaaaaa cattacaaaa
    62461 aatggcaaat ggaaaagaaa tcacggtctt tggttcggga aggacagatg ccggagtaca
    62521 tgcgattggg caagtaatcc attttgatta tccagaggag cgtccgttag aacgaatgcg
    62581 tttcgcgcta gatacccagt caccagagga tattgctgta agacaagtag aaattgtttc
    62641 agaagacttc cacgcaagat atttggtcaa agaaaagacg tatcaatttc gagtggatat
    62701 agggaaacca cgcagtcctt ttcgacgcca ttatgcaagt tattttcctt accctcttga
    62761 tttggaaaaa attcagcggg cgcttcctga tttattaggg actcacgatt tcacctcttt
    62821 ttgtgcatca ggaagctcga tagaggataa agtacgtacg atctacgagg ctaagatgga
    62881 ggtaaatgaa acaaaagacg aattgttgtt tacatttagg ggaaatggct tcttgtataa
    62941 gatgatacgg atcttagtag gaacgctttt gaaaattggc aatggccgat tgcctgaaga
    63001 tagtatccca gatattattg cgaaaaaaga tcgtaatgca gcaggaccta cagcacatcc
    63061 tgaaggactt tatttgtatg aagtgaaata tgaataagag gttgtgacag aagtggtcag
    63121 cttcaagaaa taagaaggaa tttacgaaaa ttacttctca aaattttgca aaatttcggc
    63181 ttattttcga aggagctact tctggaacac cgtgaatcag aggttgtgaa aaagctgccc
    63241 tgcatcaagt aataagaaca accaaacaaa aatagctcgt catatttttc gtttggttgg
    63301 gcttattacc gcagatgcaa gcttttgaac accgtttaag gaagaggttg tgaaatcagc
    63361 gttttgacct gagtattaga gaaacaaacg gaaaaatagt tcctcatatt ttgccgtttg
    63421 ttgagctaat accgaaggtc agctgattga acaccgttta agaaagaggt cgtgagcctg
    63481 tcatttaact ctgagtcaca agtaacaatt tcaaaaaaca gcttctcatc tttgatgaat
    63541 atcgtgactt gtggacgagg cgttgataag tgaatcatct ttttgttacc tattttttct
    63601 gtaaccaaaa aacgatggaa cgttgttttg attgccctta atgaggacag tcggaacagg
    63661 tttgtcattt ttatatttaa atggcacaaa tttttctaat tatttgtcat ttagcgctga
    63721 aaatttttgc tatttatcta aaaaagtgat aactacttaa gatgaagcag aatatttacg
    63781 ccatacggca tacaaccgcg aaaaatataa aaaaaagaaa acgattgaac gcgtttttgc
    63841 agtcgcaaag gaaaagcatg gaatgcgcta catcaagtat cgagacttgg aaaacaatca
    63901 ggtgtatacg ctgattgttt ttgctgcaat gaatctgaaa aagttgtcca cttggcagtt
    63961 ggaacatatg tcttcatatc ttttattata caaaaatagc aaaagcacca gtctacactc
    64021 ttagtaaaga ggaaactgat ccttttgtct acattcttaa agtacttaaa ctaagtactt
    64081 tattttactc tttaggattg atacagtagc atctatccct ttattaataa tcttttattt
    64141 ttttaaataa agatgttgtc tccatcttca ggcactaaaa ctttttcgga aattcctttt
    64201 tctttattga aagactttaa ttcttctctt gacagtcccc aatggtttac agcttccata
    64261 tgaacggcaa taattgtgga atctggtatt gctttatgca attcatataa atcgtctttc
    64321 cccataataa gagattctcc aactaaaaaa tgattatctc cagcatttgc tactatgatt
    64381 tctggattat actgatcaat agtttgttta acagcttcat accaaactgt atctcctgta
    64441 aagtatagtg tcttctcagt cgaatgtttg aaaacaatac cgcaaacatt acctacataa
    64501 ttcaagattt ctcctctgcc atgtttgcct tttgttttaa ccaattgtat agattcaaaa
    64561 actgtgtctt ctcgtagtac ctccacattt ttaaaaccat atagtcgaat ttcattcgca
    64621 tcattttcat cttgcacaaa taattttatt tctttaggta ggacctcttt cgctatatcg
    64681 tcccaatgat ctagatgtaa atgtgttaca ataacagcat caataccgtt gataatatct
    64741 tcgactggca ttggcaaatc aactagagga ttcatttgat cttttcttgg tgatggaaaa
    64801 ggacctttcg aaataaatgg tggaagtgtt cctttttccg ctaacattgg atcaattaaa
    64861 aattttttac ctccatagtc taagatagct gttgcattac gaatgtgatg tatattcata
    64921 aacgttgtct cctttttgtt gatatgaaat atttttagta taattcaatt ccatacaata
    64981 aataaaccga acaaaaaaag tcttttacta tttttactta atttatgaaa ggttgtttac
    65041 catgttagac caaacagata taaatatcat tgaggaacta tcaaaaaata gtcgaatcac
    65101 aatgaaagaa cttggagaaa aagtacattt gactggaccc gctgtctcgg cgagagtgac
    65161 aaaactagag gaaagtggag ttattgaaaa ttatacagta aaattaaata tggaaaagct
    65221 agggttttcg attcacgctt ttttaattat aattacgcaa aatttaaatc ataaacccta
    65281 tttatcattt attaaaaatc atgaaaaatt cttgattaga aattataaga ttagtggagg
    65341 gggctgttat cttttggaat gtagatttac ttcaaaaaaa tcaatgaaca gctttttgga
    65401 acagcttaat gaatatgcga attataaatt atctattgtt atagattaat aataaaacta
    65461 gcagatggta aaaatactaa tatgcgagac acacattcaa ccataactat ataacttatc
    65521 aatttaaaac taaactgatg gaaacaagta aggcaaaaac atttatattt tgccctactt
    65581 atttttttaa ttaaattcat tgatgattca tatttagaaa attctatgaa ggccaaatga
    65641 gtatcctgtc acttttttag ataaatagca aaaattttca gcgttaaatg acaaataatt
    65701 agaaatattt gtgccattta aatataaaaa tgacaccaag tatatcatga acgcacaaaa
    65761 agaccaacag ggtataccct gttggtctaa ataa
//
LOCUS       DADGKS010000010        61701 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.010, whole genome shotgun sequence.
ACCESSION   DADGKS010000010 DADGKS010000000
VERSION     DADGKS010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61701
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.010"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(132..509)
                     /locus_tag="JXV47_000672"
     CDS             complement(132..509)
                     /locus_tag="JXV47_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486735.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            765..1493
                     /locus_tag="JXV47_000673"
     CDS             765..1493
                     /locus_tag="JXV47_000673"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HAX1486736.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            1493..1747
                     /gene="purS"
                     /locus_tag="JXV47_000674"
     CDS             1493..1747
                     /gene="purS"
                     /locus_tag="JXV47_000674"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HAX1486737.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1749..2420
                     /gene="purQ"
                     /locus_tag="JXV47_000675"
     CDS             1749..2420
                     /gene="purQ"
                     /locus_tag="JXV47_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HAX1486738.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            2421..4643
                     /gene="purL"
                     /locus_tag="JXV47_000676"
     CDS             2421..4643
                     /gene="purL"
                     /locus_tag="JXV47_000676"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HAX1486739.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            4628..6067
                     /locus_tag="JXV47_000677"
     CDS             4628..6067
                     /locus_tag="JXV47_000677"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010768528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HAX1486740.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            6099..7142
                     /locus_tag="JXV47_000678"
     CDS             6099..7142
                     /locus_tag="JXV47_000678"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HAX1486741.1"
                     /translation="MANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGFGGC
                     FDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEPLYF
                     LDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFAVGI
                     AEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKKTLG
                     EELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSWPIL
                     PIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVQESKVKEIVHEIEQAGEKVYEIGKVIA
                     KEKHRVVFIGEER"
     gene            7139..7717
                     /gene="purN"
                     /locus_tag="JXV47_000679"
     CDS             7139..7717
                     /gene="purN"
                     /locus_tag="JXV47_000679"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HAX1486742.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7714..9249
                     /gene="purH"
                     /locus_tag="JXV47_000680"
     CDS             7714..9249
                     /gene="purH"
                     /locus_tag="JXV47_000680"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HAX1486743.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            9265..10539
                     /gene="purD"
                     /locus_tag="JXV47_000681"
     CDS             9265..10539
                     /gene="purD"
                     /locus_tag="JXV47_000681"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HAX1486744.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            10661..11575
                     /locus_tag="JXV47_000682"
     CDS             10661..11575
                     /locus_tag="JXV47_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HAX1486745.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11708..13273)
                     /locus_tag="JXV47_000683"
     CDS             complement(11708..13273)
                     /locus_tag="JXV47_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAX1486746.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(13266..14717)
                     /locus_tag="JXV47_000684"
     CDS             complement(13266..14717)
                     /locus_tag="JXV47_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAX1486747.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14731..15747)
                     /locus_tag="JXV47_000685"
     CDS             complement(14731..15747)
                     /locus_tag="JXV47_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAX1486748.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15967..17055
                     /locus_tag="JXV47_000686"
     CDS             15967..17055
                     /locus_tag="JXV47_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAX1486749.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            17109..18635
                     /locus_tag="JXV47_000687"
     CDS             17109..18635
                     /locus_tag="JXV47_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HAX1486750.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            18637..19831
                     /locus_tag="JXV47_000688"
                     /pseudo
     CDS             18637..19831
                     /locus_tag="JXV47_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            20088..21065
                     /gene="guaC"
                     /locus_tag="JXV47_000689"
     CDS             20088..21065
                     /gene="guaC"
                     /locus_tag="JXV47_000689"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HAX1486751.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            21329..22753
                     /locus_tag="JXV47_000690"
     CDS             21329..22753
                     /locus_tag="JXV47_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAX1486752.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            23214..24323
                     /gene="pdhA"
                     /locus_tag="JXV47_000691"
     CDS             23214..24323
                     /gene="pdhA"
                     /locus_tag="JXV47_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HAX1486753.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            24326..25303
                     /locus_tag="JXV47_000692"
     CDS             24326..25303
                     /locus_tag="JXV47_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HAX1486754.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            25328..26971
                     /locus_tag="JXV47_000693"
     CDS             25328..26971
                     /locus_tag="JXV47_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005236379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HAX1486755.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            26979..28385
                     /gene="lpdA"
                     /locus_tag="JXV47_000694"
     CDS             26979..28385
                     /gene="lpdA"
                     /locus_tag="JXV47_000694"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HAX1486756.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            28547..28822
                     /locus_tag="JXV47_000695"
     CDS             28547..28822
                     /locus_tag="JXV47_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HAX1486757.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            28828..29595
                     /locus_tag="JXV47_000696"
     CDS             28828..29595
                     /locus_tag="JXV47_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HAX1486758.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            29763..31592
                     /gene="typA"
                     /locus_tag="JXV47_000697"
     CDS             29763..31592
                     /gene="typA"
                     /locus_tag="JXV47_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HAX1486759.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            31853..33625
                     /gene="recQ"
                     /locus_tag="JXV47_000698"
     CDS             31853..33625
                     /gene="recQ"
                     /locus_tag="JXV47_000698"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HAX1486760.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            33739..34041
                     /locus_tag="JXV47_000699"
     CDS             33739..34041
                     /locus_tag="JXV47_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HAX1486761.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            34044..35207
                     /locus_tag="JXV47_000700"
     CDS             34044..35207
                     /locus_tag="JXV47_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAX1486762.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            35233..38661
                     /locus_tag="JXV47_000701"
     CDS             35233..38661
                     /locus_tag="JXV47_000701"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HAX1486763.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            38682..39806
                     /locus_tag="JXV47_000702"
     CDS             38682..39806
                     /locus_tag="JXV47_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486764.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            39796..40233
                     /locus_tag="JXV47_000703"
     CDS             39796..40233
                     /locus_tag="JXV47_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAX1486765.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            40217..40555
                     /locus_tag="JXV47_000704"
     CDS             40217..40555
                     /locus_tag="JXV47_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HAX1486766.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            40674..41234
                     /gene="rsmD"
                     /locus_tag="JXV47_000705"
     CDS             40674..41234
                     /gene="rsmD"
                     /locus_tag="JXV47_000705"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HAX1486767.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            41231..41722
                     /gene="coaD"
                     /locus_tag="JXV47_000706"
     CDS             41231..41722
                     /gene="coaD"
                     /locus_tag="JXV47_000706"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HAX1486768.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            41712..42755
                     /locus_tag="JXV47_000707"
     CDS             41712..42755
                     /locus_tag="JXV47_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAX1486769.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            42914..43642
                     /locus_tag="JXV47_000708"
     CDS             42914..43642
                     /locus_tag="JXV47_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComEA"
                     /protein_id="HAX1486770.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            43758..44003
                     /locus_tag="JXV47_000709"
     CDS             43758..44003
                     /locus_tag="JXV47_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAX1486771.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            44000..44218
                     /locus_tag="JXV47_000710"
     CDS             44000..44218
                     /locus_tag="JXV47_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HAX1486772.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            44354..44893
                     /locus_tag="JXV47_000711"
     CDS             44354..44893
                     /locus_tag="JXV47_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HAX1486773.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            44886..47159
                     /locus_tag="JXV47_000712"
     CDS             44886..47159
                     /locus_tag="JXV47_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HAX1486774.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            47197..48243
                     /gene="holA"
                     /locus_tag="JXV47_000713"
     CDS             47197..48243
                     /gene="holA"
                     /locus_tag="JXV47_000713"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HAX1486775.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(48332..48586)
                     /locus_tag="JXV47_000714"
     CDS             complement(48332..48586)
                     /locus_tag="JXV47_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HAX1486776.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(48986..49255)
                     /locus_tag="JXV47_000715"
     CDS             complement(48986..49255)
                     /locus_tag="JXV47_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486777.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(49725..50180)
                     /locus_tag="JXV47_000716"
     CDS             complement(49725..50180)
                     /locus_tag="JXV47_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HAX1486778.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(50318..52246)
                     /locus_tag="JXV47_000717"
     CDS             complement(50318..52246)
                     /locus_tag="JXV47_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAX1486779.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(52443..53276)
                     /locus_tag="JXV47_000718"
     CDS             complement(52443..53276)
                     /locus_tag="JXV47_000718"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HAX1486780.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(53468..54172)
                     /locus_tag="JXV47_000719"
     CDS             complement(53468..54172)
                     /locus_tag="JXV47_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAX1486781.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(54195..54821)
                     /locus_tag="JXV47_000720"
     CDS             complement(54195..54821)
                     /locus_tag="JXV47_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAX1486782.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            55147..57522
                     /locus_tag="JXV47_000721"
     CDS             55147..57522
                     /locus_tag="JXV47_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HAX1486783.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(57546..58037)
                     /locus_tag="JXV47_000722"
     CDS             complement(57546..58037)
                     /locus_tag="JXV47_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HAX1486784.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            58224..59144
                     /locus_tag="JXV47_000723"
     CDS             58224..59144
                     /locus_tag="JXV47_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAX1486785.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            59298..59642
                     /locus_tag="JXV47_000724"
     CDS             59298..59642
                     /locus_tag="JXV47_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HAX1486786.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(59832..60332)
                     /locus_tag="JXV47_000725"
     CDS             complement(59832..60332)
                     /locus_tag="JXV47_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1486787.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            60860..60943
                     /locus_tag="JXV47_000726"
     tRNA            60860..60943
                     /locus_tag="JXV47_000726"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:60894..60896,aa:Leu,seq:cag)
     gene            complement(61267..>61701)
                     /locus_tag="JXV47_000727"
     CDS             complement(61267..>61701)
                     /locus_tag="JXV47_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HAX1486788.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT        20234 a        10662 c        13216 g        17589 t
ORIGIN      
        1 caaaaaagaa gcagatccgt tagcggttct gcttctttta gtttattata ttttcttatc
       61 aataatagga acctgatttt aaaagcggct acctctttac cgtgcctctt tacatacaaa
      121 aaatagagga attaagcgta aatggcttgg ctattataac taaaatgctg gttatggaga
      181 tgttgcagca agttttcgag aaaagcgtat tccatctctt gtccattgaa taagatctgg
      241 atacgataat gatttttgaa acgcttctgt tcatgaatct gactgattga aagttcgcct
      301 ttgtgttctg tctgataaag aaaagtcctt ttacggcatt cagcacagcg cttggttgct
      361 cggcggattt ttcggaatgt ataaaaacta gtatctttat tgcataaata aacgtctttg
      421 atcgacagca aatcattata tagacaggaa cgttcttcag ctgttaattc tgataaaaaa
      481 agctgacctt gttttattgc atcttccatc ggcaagtgcc tcctcgaacc cattatccaa
      541 atttttagtt aattctaata taccatcatt aagtataaat gtaaacgctt gttgatggta
      601 taagattttc gtttctgata aaacacgaac attaaaagaa tctaatgcct taaatgtaca
      661 tatttttgtt gatttataaa aagatgattg ctaaaattta aagtgaaaaa acgaacaaaa
      721 aacgatgtat ttgcttttaa tgtaaataaa aaggagagac gtacatggag aagaaagaac
      781 ttttgtatga aggaaaagcc aaaaaaatat atcttacttc tgatgagaac ttgatttgga
      841 tagaatattt agatcaagca actgcgttga atggcgcgag gaaagaccag ataagtggaa
      901 aaggagaatt gaataatcaa atcacaagtg caattttccg ttatctgact caaagaggaa
      961 taaaaaatca ttttattgaa caattgtcta aaaccgaaca attagcaaaa aaagtacaaa
     1021 ttatccctct ggaagtggtt atccgaaata ttgcagcagg aagtttctca aaacgtctag
     1081 gtgttcccga aggtaaagaa ttcatcaaac caatcattga attctactat aaggatgacc
     1141 agttggatga tccatttatc aatgaagagc atatctattt cttacaactt gcaaagccgg
     1201 aagaaatcag tgagctgaaa gcccaagcgt tggctattaa tgaaattttg accgaattat
     1261 ttgctaaggt cggtttggtt ttagtagatt tcaagctaga atttggccgg tcgaatggac
     1321 aaattttgct tgcggatgaa gtaacaccgg atacttgccg attatgggat gaacgtacga
     1381 atgaacatat ggacaaagac gtttaccgca gagatctagg tgatttgatc ccagtctatc
     1441 aagaagtata taaccgtcta tcggaactaa ctgaagaaaa ggagcgagta tgatgtattt
     1501 cgtaaaagta tatgtaacct ataaagattc agtgttagat cctcaagggg aggcagtaaa
     1561 aaaagcagtc catcgtatgg gatatgaaac aatcgaagat atccgaatag gaaaatactt
     1621 tgagatacaa cttgctgatg cagaagaacc aatcgataca gtgattgaaa cgatttgtga
     1681 caagctgctt gcaaatgtaa atatggaaac ataccgatat gaaatcaaaa aaatggagga
     1741 agtataacat gaaatttgcg gtcatcgttt ttccaggttc aaattgtgac gcagatatgt
     1801 tatgggcagt tcgcgagatc atgggcgctg atgccgaatt tgtacggcat gatgagtcct
     1861 ctttagaagg atttgatggg gttttactgc cgggaggatt ctcctatggt gactatttga
     1921 gatgcggtgc gattgctcgg ttttctacaa tcatggaaga agtgattcgt tttgctgaag
     1981 aagggaaacc agtattcggt acatgcaatg gattccagat attgacagaa gcaggacttt
     2041 tgccaggtgt actgagacga aatgagtctt tgcattttat ttgcaaaact gtaccattga
     2101 aagtcaaccc caagacggcc tttacttcag agtatgaagc cgacgaaata atctatcttc
     2161 cagttgctca tggggaagga aattatttct gtgacgaaga aacacttcaa gaactaaaaa
     2221 aaaataatca gattgccttt acttataatg acaacatcaa cggcagcgtg gaaaacattg
     2281 cagggattac gaacaaagca gggaatgtgt taggaatgat gcctcatcca gaacgtgcag
     2341 tagaagactt gctaggatca gaagatggga aacggttctt tgcttccatt ttaaaaaact
     2401 tcggaaaggt gaccgtatag atgaaaacat tgaaagaacc gacagctgaa gagatcaaga
     2461 aaaaaagaat ctatgccgaa tggggattga ctgatgaaga atatcgaatg atcgaagaag
     2521 atatcttagg aagaatgcct aattatacgg aaactggact gttttctgtt atgtggagcg
     2581 aacattgttc ctataaaaat tctaaaccgg ttctacgcaa atttcctact agtggacctc
     2641 atgtgttgca aggccctgga gaaggcgcag gcatcgtcga catcggtgat ggactagcag
     2701 ttgtcttcaa agcagaaagt cacaatcatc cttcagccgt ggagccttat gaaggagctg
     2761 cgacaggagt tggcggaatc atcagagata ttttcagcat gggggctcgt ccaattgcgt
     2821 tgctagattc attgaggttc ggcgaattag ataatccaag aacgaaatat ttactagaag
     2881 aagtagttgc aggtatcggc ggatacggca attgtatcgg cataccgact gtaggcggcg
     2941 aaattgcatt tgatccttgt tatgaaggaa acccattagt caatgcaatg tgcgtaggtt
     3001 tgattgaaca caaacatatc cagaaagggc aagccgctgg cgtcggtaat tcgatcatgt
     3061 atgtaggtgc aaaaacaggt cgcgacggta tccacggagc aacttttgcc tcagaagaat
     3121 ttaatcaaga agaagaacag caacgttctg ctgtacaagt aggcgatcct tttatggaaa
     3181 agctgctgct tgaagcgtgt ttggaattaa tcttgcatca ttcggattct ctaataggta
     3241 tacaggatat gggagcagca ggacttgttt catctagtgc ggaaatggct tcaaaagctg
     3301 gctcaggact tatattgaca ttagatgaag tcccacaaag agaaactggg atgacacctt
     3361 atgaaatgat gttatcggaa tcacaagaac ggatgttgat ttgtgttaaa tcaggagagg
     3421 aagaaaaaat ccaagaacta tttcagaagt atgatctaga tgcagtcact atcggtaaag
     3481 taacagacga cgggcaatat cggctatatc atcaaggaga agaagtagca aatctgccag
     3541 tcgatgcatt agctgaagat gcaccagttt atcataaaga aatgaaagaa ccagctcgaa
     3601 tcgtagaatt tcagcagtta gctccttatc agccagttat cgaagaacct ggacaagtat
     3661 tgcttgatct gctgcagcaa ccgacgattg cttcaaaacg ttcaatctac gaaacttatg
     3721 attcacaagt acaaaccaat acagttgtcc gtccaggaag cgatgctgct gtgatgaggg
     3781 ttagagggac gaataaagcg ttagctatga ccacagactg caacgcgcgc tatctgtatt
     3841 tggatccaaa aatcggagga caaatagcag tggcagaagc tgctagaaat attattgcta
     3901 gcggtggtaa gcccttggcg atcaccgact gcctgaacta tggttctcct gataaaccag
     3961 aagttttttg ggaattatcg acttcagctg acggaattgc tgctgcgtgt gaaacgttag
     4021 gaactcctgt tatttcagga aatgtctctt tatataatga aacggatggt caagcaatct
     4081 atccaacacc aatgattggt atggtcggat tgattgagga tcataaacat atcactactc
     4141 aggaattcaa aaaatcaggg gatctaatct atatattagg taagacgttt gcagattttg
     4201 atggcagtga attacaaaag atgcagcttg gaagaatcga aggtgtgatc cgaaactttg
     4261 atctatccat tgaaaagaga aaccaagagt tagtattgac agccatccaa aacggattga
     4321 ttgaaagtgc tcatgactgt tcagaaggtg gcttggcaat tgcactggca gaatcagctt
     4381 tcaaacatca gctagggata tctgtacagt ttgaattgtc ctctgctcaa ttatttgcag
     4441 aaactcaatc aagatttgtg ttgacagtcg caccggaaaa taagacacga ttcgaagaaa
     4501 tgatgggaga tgctgctgtt ttagcaggta aggtgacgga tgaagcgata atcgaaattt
     4561 cagcaactga cggtcagatc aaaatagaaa ctgcagtagc aagaaagtgc tgggaggatg
     4621 caatcgtatg tcttatgaag tgaagagttt aaatgaagaa tgcgggatct tcggtgtttg
     4681 gggtcatcca gacgccgcta gtgtggcata cttcgggctc catagtcttc agcatcgagg
     4741 acaagaaggt gcaggtatcg tgtccaatga tcgaggaaag cttaaggggc atcgagattt
     4801 ggggctgctt tctgaggtat tcaaagatca aagaaaattg cagcagttaa caggagaagc
     4861 tgcaatcgga catgtacgtt atgcaacagc aggcaatgga agtgtggaca atattcagcc
     4921 ttttctattc aaatttcatg atcagtcgat cggcttagcg cataatggta acttgatcaa
     4981 tgctcgttcc cttagaaaag agttagagga aaatggggcg atcttccatt ctaactccga
     5041 tacggagata ttgatgcatt tgatccgacg aagtgaagaa acagattttt taaataaatt
     5101 aaaaagtgct ttgaatgaag tcaaaggtgg ctttgcctat ttattaatga cagaaacggc
     5161 aatgattgcc gctttggacc caaatggttt tcgtccatta gcaatcggac aaatgaaaaa
     5221 cggagcatac gtgattgcct cggaaacttg tgcattagaa gttattgggg cacgttttat
     5281 aagagatgtc cagcctggtg agatagtgat catcaatgac gaaggaatcc agattgattg
     5341 ctttacgaag gacacgcagc tttctatttg ttcgatggaa tatatctatt ttgccagacc
     5401 agattcaaac atcgcaggga tcaatgtgca tactgcacgg aaaaatatgg gacggaattt
     5461 agcgaaagaa tcgccagtaa aagcagatat ggtcgttggc gtacctaatt cttctttgtc
     5521 agccgcaagc ggttatgcgg aagctagtgg aatcccttat gaaatcggat tagtaaaaaa
     5581 tcaatacatt gcccgaacat ttatccagcc aacgcctgag ctaagagagc aaggtgttcg
     5641 aatgaaatta tctgctgtac gaggagtagt ggaaggtaaa aaggtgatta tggtcgatga
     5701 ttcaattgtt cggggtacga caagcagacg gatcgtccat cttttgaaag aagcaggggc
     5761 aaaagaagtc catgtgagga ttgcttctcc tcctttgaaa tatccatgtt tttacgggat
     5821 tgatattcaa acgcgtaaag aactcattgc ggcaaatcac acgattgatg aaatcaaaga
     5881 atgtatcggt gcagattctt taggtttttt aagtgaagag ggtctgatcg aatcgatcgg
     5941 tctggaaaaa gatgctccgt attcaggatt gtgtatggct tatttcaacg gagattatcc
     6001 gacgccgtta tatgactatg aagaaaaata tcaggaatca ctaaaagaaa aagtatcgtt
     6061 cttttaaaag cagaccaaga agggagtata tgaattcaat ggcaaatgca tacgcaaaag
     6121 ctggcgtaga tgtcgaagct ggatatgaag tagtagaacg gatcaagaag catgtcaaaa
     6181 aaacggaacg tttaggtatg atgggcgcta taggaggatt cggcggttgt tttgatttat
     6241 cggtctttca attaaaagag ccagtccttg tctcggggac cgatggcgtg gggacgaaat
     6301 tagcagtggc aatcgaagca gacaaacacg atacaatcgg gatcgactgc gtagcgatgt
     6361 gtgtcaatga tatcttagca caaggcgcag agccgttata tttcttagac tacttagcaa
     6421 cggggaaaaa tgatccgtta cgtttggaaa atgtagtaaa aggtgtagca gatggatgtg
     6481 ttcaaggaaa tatggcgctg attggcggag aaacagctga aatgcctggt atgtactcag
     6541 gtaatgatta tgatctagcc ggatttgctg tagggatagc tgaaaaatct caattattga
     6601 caggagaaac gatcaaccca ggagatgtgt tgcttggaat agcatctagc gggattcatt
     6661 caaatgggta ctctcttgtt cgcaaaattt tctttgagca gcagcagttt tctttatcat
     6721 caaaactgcc agaattgaaa aaaacacttg gcgaagaatt gcttgagcca acgaaaatct
     6781 atgtttcttc cttgcttccg ctgatcaaag aaaagaaaat aaaaggagct gcacatatca
     6841 ctggtggagg gtttgtagaa aatatcccgc gaatgttacc agaatctatg gctgcacaaa
     6901 tcaaacttgg ctcatggccg attcttccaa tattcggctg tttacaaaaa tatggtgaaa
     6961 ttcctgagat ggagatgtat gaaatcttca atatgggcat cggtatggtc ctggcagtcc
     7021 aagaatcgaa agtaaaagaa atagtacacg aaattgagca agctggcgaa aaagtttatg
     7081 aaatcgggaa agtgatcgcc aaagaaaaac atcgtgtggt gtttatagga gaagaacgat
     7141 gagaatcgct gtttttgctt ctggaaacgg aagcaacttt caagcgctag ccgattatct
     7201 atcgaaaaaa ggattggaat cttcgattga ctggttgttt tgtgatcagc ctgaagcata
     7261 tgttttgaaa cgtgcaactg cgttgagtgt accggcagat tgtttttcac ctaaagaatt
     7321 tgattcaaaa aaagagtatg aagaagcaat tttgcataaa ttgaaagaaa aaaagatcga
     7381 tttgatcgta ttagctggat atatgcgaat cattggaccg gtattgctga aaaattatga
     7441 taaaagaatc atcaatatcc atccgtctct tttacctgcc ttccctggtt tgcatggcat
     7501 acgtgatgcc tttgaagctg gagtaaaaga aacgggtgtc acaattcatt atatcgacca
     7561 aggtgtagat actggaccaa tcatccggca ggaaaaagtg agaattgaac aggaggacac
     7621 gttcgattct ttagaagaaa aaatccatag agtagagcat cgaatctatc cagaagtgat
     7681 tagtgaaatt attgaaaatg gaggctatct gaaatgacaa gagcattgat cagtgtatca
     7741 gataaaactg ggattgtagc attcgcccaa ggtttgattg aacaaggagt agaaatcatt
     7801 tcaacaggag gaacaaagca tgcgttggat aaagctggga tcaaaacgct ttcgatcgaa
     7861 gaagtgacag ggtttcctga aatgatggat ggccgtgtca aaacacttca tcctaaaatc
     7921 catggtggtc ttttaggaag acgcgatctc cctagccata tggaggcaat ggaaacggaa
     7981 aatatccaac caatcgactt tgtttgtgtc aatttatatc ctttcaaaga aacgattatg
     8041 aaaccagatg tcgaaatagc agaagctatt gaaaacattg atatcggtgg tcctagtatg
     8101 ctccgtagtg cagcaaaaaa ccatgaattt gtcacctctg ttgttgatcc atctgactat
     8161 gaagaagtac tttcagaatt acgtcagtat gggcatactt cactttcttt cagacaaaaa
     8221 ctagcggcaa aagtctttcg tcatactgcg gcatatgatg cactgatcgc tcaatactta
     8281 acggattggg tggaagaaaa agaaccggaa aaattgacac ttacgtatga acgaaaacaa
     8341 acgcttcgtt acggtgaaaa tagccatcaa gccgctgcct tttatcagtc cgctcttctg
     8401 gaaaaatatt cgatcgcagc agcaaaacaa ctccatggga aagaactttc ttataataat
     8461 atccgagatg cagatgctgc gctacggatc atgaaggaat atgacgagcc aacggtagtc
     8521 gccttgaaac acatgaatcc ttgtggtatt gggacagcat ctacgatttt agaagcgtgg
     8581 gaagcagcgt atgaagcaga tcctgtttca atctttggtg ggatcatcgt tttgaatcga
     8641 gaagtagatc tgccaacagc agaacagatg cataagctgt ttctagaaat catcattgcc
     8701 ccttcttata cacaagaagc tttggaatta ctgcaaaaaa agaaaaacat ccgattactg
     8761 acagtagact ttgcgcagga agaaaatcaa aatcgagaag aaacggtctc agtcttaggt
     8821 ggacttcttg tacaagatca agatctggca atagaaaatg aagaagagtg gaaagtcgtg
     8881 acaaaacgta agccgactcc agcagaagca aaagcattag cgtttgcttg gagagctgtc
     8941 aaacatgtga aatctaatgc gatcgtactg gcaaacgaac gtcagacagt aggaatcgga
     9001 gccgggcaga tgaatcgagt cggttcagta aaaattgcga ttgaacaagc gcaagagaaa
     9061 atggaaggtg cagttttagc tagcgatgct tattttccaa tggatgattc ggttgaatat
     9121 gcagccaaac atggtataaa agcaatcatt cagccaggag gaagcatcaa agaccaagat
     9181 tctattgata tggcgaataa atacgatcta gcaatggtct ttactgatgt tcggcatttt
     9241 agacattaga gaggagtcgg ataaatgaac attttggtga tcggtgcagg tggtcgtgaa
     9301 catgcaataa gtaaaaaact tttagccagt ccgaaggtgg atacggtgta ttgtgcgcca
     9361 ggaaatccgg ggatgacaaa agatggtatc aattgtgtcg ctatcagtga gcgagatcat
     9421 tcagcgttaa tccattttgt taagaaagag gctattgatt ggagtatcgt tggtcctgaa
     9481 gttcctttgt taaatgggat cgtcgatgat tttatggcgg aaggattgaa aatcttcggt
     9541 ccgacaaaag cagcagctct gatcgaaggt tcgaaaagtt ttgctaaaca attaatggat
     9601 acttatcaaa tcccgacagc taaatccaga agttttgaat gttacgaaaa agcagcagcg
     9661 tatatcaaag aaaatggtgc gccaatcgta gtgaaagcgg acggcttagc agctgggaaa
     9721 ggtgtagtcg tggctaccac agtgaaggaa gcgctggatg cggcagaaca aatgttgaac
     9781 cagcatcgat ttggggatag tagcaaaaaa atcgtcgtag aagagttttt ggcaggagaa
     9841 gaattctccc ttttggcgtt tgtccgtaat accaaggtgt atccgatggt catttcgcaa
     9901 gatcataagc gggcatttga taacgataaa gggccaaata caggcggaat gggtgcttat
     9961 tcaccagtac cgcaaatttc aaaaaagatg attgaaaaag ctgtggaaga agttttaaaa
    10021 ccagcggctt tgggaatgaa agaactagga cgctctttca cgggtgtttt atatgcgggt
    10081 ttgattgcta cgaaggaagg accaaaagtg atcgaattca atgcgcgttt cggtgatcct
    10141 gaaacgcaag tcgttctttc tcggttgaag agtgactttg cgcaagtaat cgatgattta
    10201 ttagagaatc gtacagtaga gttaaagtgg cagcaagaag gatacaatgt aggcgttgtg
    10261 gttgcagctg ccggttaccc cgaagaatat gagacaggaa tggttctacc agattttctg
    10321 gaagaagagc tttctgttta ctatgctgga gtttcctcaa ataacggcaa actagttgga
    10381 gcaggaggac gtctttattt agtagaagca tacggtgaga cgatcaaaga agcacagaaa
    10441 aaaatttaca ccgcgttaat ggataaaacg acagatggaa cattttatcg tacagatatt
    10501 ggagaaaaag ctgccaatag cgaactgatc gtgaagtaaa tcagctgctt ccatttataa
    10561 aaaatacaac aaacataatc ggaagcgccg attttagtga agccttttca taaagagtgt
    10621 ggtacacttt tgttgtgtat ataaataagg aggagttcag atgaaaaaaa ttcaattagg
    10681 tacttctgat cagaaagcag ctgcagtgat cttaggctgt atgcgtatca acaatgcgga
    10741 agatccagta aaagtgattg agacagctta tgaaaacggc attgattttt ttgaccatgc
    10801 agatatttat ggaaacggtg aatgtgaaga aatctttgca gatgctctag caaaaacatc
    10861 aatcaaacga gaagatcttt ttattcaaac aaaatgtgga atcgttccag gtgtgatgtt
    10921 tgatttttct aaaaaacata tcattgaatc tgtagaaaaa agtttgaccc gtctgaaaat
    10981 ggattatgtg gatgctttac ttcttcatcg tccagataca ttggtagaac cagaggaagt
    11041 agctgaagcg tttgatgaat tggaacggtc aggaaaagtt cgttattttg gcgtcagcaa
    11101 tcaaaaacca atgcaaatcg aattgctgaa aaaatatgtt cgtcaaccat tagtagctaa
    11161 tcagctgcaa tttggcttga aacatactgg aatgatcgat caagggattc atgtcaatat
    11221 gacagatgaa gcaagtatcg atcatgacgg tagtgtactt gattattccc gattgcatga
    11281 tatgacgatc caagcatggt caccatacca gtatggattt tttgaaggtg tatttatcgg
    11341 gaacgaaaaa ttccctgaat taaaccaaac attagaagaa ctagcagcta aatatcaaac
    11401 gacaccaact ggcttggctt ctgcttggat tttacgccat ccagccaata tgcaagtgat
    11461 cgccggtacg atgaacgtag ggcgaatcaa ggaaatcgct caagcttcag aaattaatat
    11521 gtctcgggaa gattggtacg aattgtaccg tgctgctgga aacattttac cttaaagatt
    11581 gtcataagca ggtcaaaagg gctataaatt aaaaagacag aataacttga aagctgtttt
    11641 cagcttcgag atattctgtc tttttttatt gcaaatggaa agagtatcat tgtacggatt
    11701 tcgtttatta gttatttttg tttttaagga aaagctgtgt ccgatattct tttggagaaa
    11761 tcccttgttt tttcttaaat aaataactga aatagttagg gtcattataa ccaatttcaa
    11821 aagcaatatc tgaaatacga tagtctgatt gctgcaataa tttttttgct aattcgattc
    11881 tttgttctgt cagataatcg atgaatgttt ggttaaacga ttgagaaaaa atcgtactga
    11941 aatgagaggg acttaatgca acttgttgag cgacccaagt taaggacata tctggatcgg
    12001 taaaattttc tttgataaaa tccaatgcat ggttcaaaat tggctgatat ttgttccttg
    12061 aaggctgtga gggcagagca gttaagaaag aaatgaacat ataaactgtc gaacggtaaa
    12121 gcgagtcgtc ggcgctgatt gctaagcgtt gactggtgga tgtgcaatga accatttctt
    12181 gcgggatttt cttttctttc aggcagacat gctggagtag cttagtcaag acaaataaac
    12241 gatataatcg tgttcgagtt ggtgtgcctt gtggtttcgt caagtgttcg atgtacttag
    12301 atacttcgtt tttcgataat gaagacaaat caagtgagag gtcaaagtaa aagacagaat
    12361 caactggaag tttcgcttct tgaatcaaat cctcatagct gataatttgt tctttaaggg
    12421 aactggcggt ttcaagtatc atctgcgtga tctcaaaaga tgcaggtaat tcgctgattc
    12481 tttctgcgac aggaccaatg gcgacagaaa aattattttt ttgtcccttt tctaattcat
    12541 ggaccaacgt ttgggctacc tgataactgg tctcgatcac attttcttca agagaatcaa
    12601 ctattaaaaa tttgatgaat cgagaggaaa cagcagagaa gatcacttgt tgattctccc
    12661 taaataaaaa cttcaaataa tcactgagat gagcgtaatc ttcaaagtct gtactgactt
    12721 ggtttgctgc taataatacg gtcatttttt tccctgctaa agagcgattg aaagattcag
    12781 caagtttcaa tgtttcactg atcgtaagtg agcctttgaa caaaccgttc aagaaatgat
    12841 tttttttcaa ttcgaaaaca agatcagaag aagtgtgcgt ttctttttgc tgcaaatcta
    12901 aagcagttac tgctttttct attgcttgtt tcaattcgct acttttaatc ggtttaagca
    12961 gataatcatc tgcctgtacc tggattgctc ctttcatata atcgaaatcg tcgaatccac
    13021 taataaatat gagacgagtc caaggaagta gtttccttgc ttcttttgaa aaagtcaacc
    13081 cgtccatgaa aggcatttgg atatcagtca gaatgatgtc gggctgtaag tcgataattg
    13141 aagacagtgc catctcacca tctccagctt cgccgacata agtgattgga taataagaac
    13201 caaggacagt tatttgttcc cgcaagttat tgcgaatgag gtattcgtct tcgatgataa
    13261 aaactttata catgtttgtt tcctccaatt gttttgggag atagagggat catcagtgtg
    13321 acagttgttc cttctcggta tttgctgtca atcgtgatag gtttttgatc atttccgtaa
    13381 taaagaagga gacgcttgtt tacgttgtaa agtccgtagc cgatactgaa atctgaatcg
    13441 atccctttgg ctaactcttt acgtatttct gccagttttt ctgcagggat gccaatcccg
    13501 ttgtctataa ctttgaattg gatcatctca tcaattttgc atgtggtaat acgaataaat
    13561 cctttgtgac ggacgtactt cgttccatgg tatacagcat tttcaatcaa tggctgcaag
    13621 atcattttta aaatagaaac aggaaaaagt gtttctggta tatcgatctt atagtcaagc
    13681 atatggccgt atcttatttt taagatgact agataatcat tgatatggct aatttctttt
    13741 tcaagaggaa tccagtcttg tcctttgctt aaagacgtac gaaaaaagcc ggaaagtgca
    13801 tgggtcatag tcagagcttc ttcaaagcag tcttgttcga tcaaagaaat aatggcatcc
    13861 aaactgttat aaataaaatg gggagtaatc tgagcttgca atacacgaac ttcactttgt
    13921 gctaaatggt attgtttcaa agcgttctcc cgtaaagact ggtttagatc ttccgccatt
    13981 ttattcatgc tagcggtaag tgtttgtaat tccagtgttt ccggcagggt taaacgaaag
    14041 ccaaggttcc ctgaagaaag ttgttctgac atctcgatca gctgattgat cggttcttgg
    14101 acctttctct ctaaaaagcg acgattcttt ttcgcataga aaaaaatggt actaagaact
    14161 ccaagttcca ctattgttaa tagaatgagc gagcggacaa gtgtcgtatt ttttttgctt
    14221 gctaagtcga tctccacacg aacaaaatct tgtaagatat ctgacagcag ttgagtgaca
    14281 gaatctacct gattgatgat ctcttcattg gtatccataa aatcttttgc caagatatta
    14341 ttgatcagct cgttttgata atcttccagt gtatcgatcg tacgtagcga tacatctaac
    14401 gtactaattt ctttaagtgt atttgtatta tttttgatct ctcgaatatc attcctaagt
    14461 tcttctagga tattttcctc attgaactca tctacggtta cttggccaga aatcaagtcc
    14521 cacatacttt ccaaaacttt ttgatcaacc ttcaaagcaa ttgcatctgc tttttggata
    14581 tttgcgatcg tctgttgata aatcaaaagc tgttgcgaat ataacagtat gctcagtagc
    14641 aaagggataa cagcaaatag aagcatggct ttgtttgctt gggcaaaaat ctgttttatg
    14701 cttaaatttt ttgtcatgat acttctccag tcaataattt ctggttggga tgttagctat
    14761 attctgctgg gaaaagacag tctcggaaat aaaaatatct ttaggtaatg tttttcctgt
    14821 ttgaatattt ccaaaataac gagtaacggt attggctaca taccagccga catcaggttt
    14881 acactcgact acacaattga cgattcctga gcgtagcttc tcgatcatat cttcttgtcc
    14941 atcaatagtt acaatgatca aatcttctcc aggtttgatt gatgtttctt ttatcgcagc
    15001 taaagcaccg tgagtcattt catcactatg gctgtataat acatcgattt cggataaatc
    15061 atttgtttct aaatatcgtt tcatctggtc ttttcctttc atccgaataa aatcaccgac
    15121 aattcggtga acaatagtca tcggaggttt atggtcgatg gttccatctt tttttagggt
    15181 tggtttacga ttgattgatt ccaaaaatcc ttcggagcgt agcttggtcg gtgtggagtt
    15241 ctctgaacca gcaagttcta ggattctgat ttcctgtttc tttgaatttg tgaagtgatt
    15301 gctgacaaat aaacccgccc gatttccttc tgctttgaaa ctggggccaa tgtgggtgac
    15361 gaaaagctcg ggatcattcg tttgaatatg tctgtcgaca agtatgacag ggatccctgc
    15421 tcgctttgct tcttttaata cagagtccca cccggattct tgcaaaggag taaaaatgat
    15481 catatccact ttataggcaa tgaacgtccg tatatcttgg atttgccgtt cctgattcat
    15541 gtagccattt cggtagagaa cttggtaatc ttctttttca agcgcagtga taattgattc
    15601 agtatgcttt ttccgccagc tactctccgt tcctgattgc gaaaaaccaa cgactagtgg
    15661 gtcaggtgct tcctttgtat taggtgtaca ccccatcatt tggtaagcga ttacaacaag
    15721 ggctaaaaaa aataaaacac gtttcacttt aaatcactcc atctggattt gttagtacta
    15781 tcttatcaga taaaagggaa aatcaaagtc aaaaggaatc aatcgaaaaa aatccaagaa
    15841 acttaaaaaa atccaagaca aaaaaagtac acctaaaaaa tttaaagtaa atcccataaa
    15901 aaaatcaatg ttaacgcttt ctttattagc tatactcggt gtatcaattg aaatggggga
    15961 taaaaaatga aaaacaaatt tagaaagatt gttgggacta tcgctatttt gaccgcaagc
    16021 attctattaa gtgcgtgtgg caattcagga tctgcagatg atagtacggg gtatgtagga
    16081 atcgctatgc cgaccaaatc agcagaaaga tggatcgctg atgggaacaa catggtctcg
    16141 gaattagaaa aactgggtta taaaacagat cttcaatatg gagaagataa agtagaaaat
    16201 caagtagcac aaatagaaaa tatgattaca aaaggggtag atacacttgt gattgcttct
    16261 atcgatggtt cggctttaac tgatgtgtta gctaaagcaa aagaagcaga tatcaaggtg
    16321 atcgcctatg atcgtttact gatgaattca gaaaatgtcg attattacgc gacttttgat
    16381 aattttggag taggtgtatc gcaagcagct tatattgaag agcacttagg attgaaagaa
    16441 ggaaaaggac cattcacgat tgaattattt ggtggctcgc ctgacgacaa caacgcacta
    16501 atcaattaca acggagtgat gtctgtttta caaccatata tggacaacgg tcagttggtc
    16561 gtgccatctg gacagacgag tttcagtcaa atcgctacgc ttcgctggga tggttctacg
    16621 gcgcaagcaa ggatggataa tctgttaagc gcaaattata ctgaccaaac attggatgct
    16681 gttttgtcgc catatgatcc aataagttta ggaatcattt cgtcattaaa aggcgtgggg
    16741 tatgggagtg aaagtaaacc tttacctgtg attactggac aagatgcgac agttgctggc
    16801 gttaaatcga tcattgccgg ggaacaaaca caaacgatct ttaaagacac acgtatctta
    16861 gcaaaaaata cgattgaaat gatcaaagca atcagtgatg gagaagaggt tccggtcaat
    16921 gatactgaaa cttatgataa tggggtgaaa actgtcccta cgtatttagc aaatacagta
    16981 tctgtcgata aagataatta tcaagcagag ctgatcgaca ccgattatta taaagaatcc
    17041 gatctgaaaa attaagagga accaaacaag gaactaaaga gatctaagtc agagagagga
    17101 taagaattat ggcggattgt attttaaaaa tggcagatat caccaaaaaa ttttctggaa
    17161 tccgagcgtt agattgcgtg aatctgatga ttgaacgtgg ggaaatccat gcattgtgcg
    17221 gagaaaacgg agcgggaaaa tcaacattga tgaatgtctt gagcggcttg tatccatatg
    17281 gctcctatga cggggaaatc ttttatgatg gaaagctgtg tcaatttaaa gatttgaaag
    17341 atagtgaaga aaaaggcatc gtcatcattc atcaagaatt agcactaagt ccttatcttt
    17401 caataaaaga gaatattttt ctcggaaatg aacaagcaga aagaggcgtg attgattggg
    17461 aactgacaga aaagaaaaca tatgaactgc tgaataaagt cggtttgtct atcgacccga
    17521 atcttctagt atcccagatt ggcgtagggc aacagcaact agttgaaata gctaaagcat
    17581 tatcaaaatc cgtccgtctg ttgattttgg atgagcctac cgctgcattg aatgaagaag
    17641 aaagcgcgaa tttgctgaga ttgatccgag agttgaaaga gcaaggtgta acctccatca
    17701 ttatttcaca taagctgaat gaaatcgtgg atatcgcaga tcgaatcacc attttacggg
    17761 atggacagac gattgagaca ctagaaaatg aaatgatcag cgaagagcat attattcgcg
    17821 gaatggtggg cagagattta gttgatcgtt atcctgaaag aaaaccggat attggagaag
    17881 tttattttaa agtagaagac tggacggtct atcaccctct tgatcacgag cgaatcataa
    17941 acgaccacat caacttgcat ttgaaaaaag gagagattgt aggaatagct ggactgatgg
    18001 gagcgggcag aactgaattc gctatgagtc tatttggaca ttcttatgga agcaagatat
    18061 ccggacgtat attaaaggaa ggggcagaga tatcagttaa gaccgttcct tcagccattg
    18121 caaacggact cgcttatgtc tcggaggacc gaaaatcttt aggactgaat ctgctgatgg
    18181 atattcggga aaacgtgacg ctgagcagtt tggataaaat aagtcaaaaa ggagtattag
    18241 ataaagaaaa agaagtaact gaggcagaaa atttccggaa aaagatgcgt ataaaaacaa
    18301 actccatcca tcaaattgtc agtagtctta gtggtgggaa tcaacaaaaa gtcgttttat
    18361 ccaagtggct gatgacacaa cccgatattc tttttttgga tgagccaacc cgtgggatag
    18421 atgttggggc aaaatatgag atctacacga ttatcgaaga aatggcagca aatggcaaag
    18481 ctgtctgtct tatctcttct gaacttcctg aaatattagg gatgtgtgat cgaatctata
    18541 cgatgaacga aggacgtatt acaggagaag tctcgcgaga agatgcagat caggaagtct
    18601 tgatgaaatt aatgacgaaa gaagaggtgg gttaagttgg aacaggcaaa aaatcttacg
    18661 gataaaaaag agaaaaaact aaatttgaaa agtagagcag ctgatctttt tggtcgctac
    18721 agcatggtga tcattttagc gggactactt attgcgtttc aattgatgac ggatggtatt
    18781 ttctggcgtc cattgaatat aactaacctt gttctgcaaa atagccatat attagtacta
    18841 gctgcaggga tgttattagt tgtgctctta ggtcatgtgg atttgtcggt agggtcagtg
    18901 atggcgtttg ttggtgcaat tgcgggcatg atgatggtca atcgccaaat gaacccgtgg
    18961 atgacagtta tcgcatgtct tgcagtaggc gggctgatcg gcgcatggca aggtttttgg
    19021 gtagcttatg cagggatacc ggcgtttatc gtgactttag caggattgct gatgtttcgt
    19081 ggactgacac aagttgttct aggaggccaa tctctagcac cttttccagc tgttttccaa
    19141 aaaatgtcta cgggttattt accagactta agcgaaggaa gcagccttca cttcttgaca
    19201 ttgattttag gaatgatcat cacgatcgtg ttagttgttg gtcaatggcg aacaagaaat
    19261 cgtcggaaaa atcatttatt tgaagtggaa tctccaacag ctttcttggt aaaggcggta
    19321 tttacagcag tcgttgtact aggaataact tatatctttg cctcttatca agggtatccg
    19381 attattttga tcattcttgg tttgatcgtt gcagcatatg ggtttttgac aagcaggtcg
    19441 acagatttat gcgacgggcg gaaatcgaaa agcggctgaa ctatcaggga tcaaaacaaa
    19501 gcgaatcacg ttctgggtat tcgtcaacat gggagtcatg gcagctttag ctggattagt
    19561 tttagctgct cgattgaatg cggcaacacc tcaagcaggt acatcgatgg aactggatgc
    19621 aatggcggca gtatattttg gtggtgcttc gacttccggc ggcattggaa caatcatggg
    19681 tgcgattgtc ggtggcttgg tcatgggtgt attgaacaat ggcatgtcga ttttaggcgt
    19741 cggggtagac tggcagcagg caatcaaagg attgatcttg cttttagccg ttgtgctaga
    19801 cttgtataat aagaaaaaac gaacaacgta ggagaacgcc ggttattcag aaaaaagact
    19861 gtgacaagac atttgtcaca gtcttttttt cgctaaaagc gaacattcat tgtttcgttt
    19921 gtatagacta aaaataatat atgttttttt accattcgta taaattctct ttttgctctt
    19981 gatttttttg cttaattgag ttaaattaca tagggcgcta aaaaaagcct tgattaaatt
    20041 aataatgttc gtgttttgct ggatgtgaac atcaggagga taatgtaatg aaagtatttg
    20101 attacgaaga tattcaatta attcctaata aatgtatcgt aaatagccgt tctgaatgtg
    20161 atacaacggt cacattaggt aaacatacat tcaaaatgcc agtagtgcct gccaacatgc
    20221 agacgattat tgatgaaaca atcgcagaat tcttagcgga aaatggttat ttctatatca
    20281 tgcatcggtt tgatgaagca gctcgaattc cgtttatcaa aaaaatgaaa aagcgtggat
    20341 tgattacctc gatcagtgtt ggcgtcaaga aagaggaata ttcctttata gagaagttgg
    20401 cagaagaatc gctaaatcct gattatatca ctatcgacat cgcgcatgga catgctaact
    20461 cagttattga tatgattcag catattaaaa aatatttgcc tgaaactttt gtgattgccg
    20521 gtaatgttgg tacaccggaa gccgtccgtg aattggaaaa tgcgggcgca gatgcaacaa
    20581 aagtcgggat tggtccagga aaagtatgta ttacaaaaat caagacaggc tttgggactg
    20641 gaggctggca actggcagct cttagatggt gtgcgaaagc agctcgcaag ccgatcatcg
    20701 ctgacggtgg gatcagaaca catggcgata ttgcaaaatc tgtccgtttt ggtgcgacaa
    20761 tggtcatgat tggttcattg tttgccggtc acgaggaatc tcctggcgaa acaaaagtcg
    20821 aaaatggaat cgtgtataaa gaatactttg gttctgcttc agaattccaa aaaggcgaaa
    20881 aacgaaatgt tgaaggaaag aaaatctgga tccaacacaa aggatctttg aaagatacac
    20941 tagtggaaat gcaacaagac cttcaatcat ctatttctta tgctggagga agagatctgg
    21001 aagccattcg aaaagttgac tatgtcatcg tgaaaaattc gatttttaat ggagacacaa
    21061 tctaaaaaat aaataaaata ttaggatgtt gtgaaaaagt tgtcctgcat taagtaataa
    21121 gaacagccaa acaaaaatag ttctttatat gttttgtttg gctggaatta ttatcgcaga
    21181 tacaagcttt tgaacatcat tattcagaat aagggactgt gataagattt ttgtcacagt
    21241 cccttatgtt ttgcaaaaaa agtttttctt ttttctcgta aattcggtaa aatcaaaaga
    21301 aaaaatagac aatagaaaag agaagcttat gtgggaaaaa gtagagaaaa aacaaggacc
    21361 gatttatcgt caaattatgg aacagattat gagagaaatc gaaaacggaa ggatcaatcc
    21421 tggaagtcaa cttgaatcag aacgaaaact agggcaactt tttggtgtga atcgttccac
    21481 cgttgtccat gcattggaag agcttaggga gcttggggta ctaacgagca aacgtggcag
    21541 cggatggttt gttaatcaga ctgaatgggg gaaattcgct gttccaagaa tcgattggcg
    21601 gcaaatgatc tctcctcgtt atgagcagac ggactggtat gagcaaaaaa taagagaagc
    21661 aaagcagatc caaaaaacat cgtttcttga tttatacgct agcgagatgc cagatgagct
    21721 tttgccgaat tttgagtttc cttcttattc tcttgaagaa atcttagcgg aagaaaaaga
    21781 aatggatctt ttaggctata ctccgttacg taacaaaatc aaacggtatt tggaaagtaa
    21841 atttgaattg gcattttccc ccaaccagct tcttgtgact ggtggcggtc agcaagcaat
    21901 ctttttgatt ttacaaacga ttctttcagc tggagagggg atagctgtag agtcaccttc
    21961 ttttttttac cgattacctc ttttcaaagc ttcaggaacg cgtttatttg ggataccgat
    22021 ggatgaagaa gggatcgact tagaaaaact gaaagaatcg atccataaaa ataaattgaa
    22081 agcagtgctt atcaacccga attttcaaaa ccctacagga aaagtgatga gtcaaaaacg
    22141 acgagaaaag ctagtagaat tgtgtcgaca gtatcggctt ccaattattg aagacgatgt
    22201 atttacggat ctttcatttc taaaccaaga agaagtcctt cctatacgaa cgattgatcc
    22261 ggataatgtg ttatacgtcg gttcgttatc tagggtttta ggaaaaacaa cgaaaatcgg
    22321 ttgggtgata ggacctgaga cttttatctc gcaactagct caagcgcaag aaatgatgga
    22381 gttttcgatg aatatcctta cacaaatcac agtggctaat gtatttaatg aagcaattga
    22441 tttgaaaatg caagatgtaa gaaaaaagtt gaaagaaaaa agccgactga taagcgcttg
    22501 gggagattca caatcgtttt tcaagcttca ttcaatttta ggtggttact atgcctggat
    22561 tacttgggat gggaaaaaac tagaccccga actagcagaa aaagtagtag atatgggtct
    22621 tggaattgca ccaagtctac tttttgggca agatataaat ggaatcagaa tcaattacag
    22681 taggctggat gaaaaccaaa taccgttgtt ttattcaaag atgaaaattc tagaaaagtg
    22741 gttaacagaa taatttcaca aagtaaatag attaaagaat ataacagctt ggatttaaat
    22801 ttcaagctgt ttcttttttt tcggaaaaag aatacgatat aaagaaacta agaaaaaacc
    22861 attatttgta cgtccgttca cgatgtgtaa ataaaataaa tgtttgcaac aaaactgtat
    22921 aacaccaacg tttttaaata gaaacagatg gttgtaagtt tgattagaaa atagaaaaaa
    22981 tgcagatgaa atataaaacg ctttccttat tgtgatttta ttcactaatg ctgttaatat
    23041 gcggattggc ataatttcct ttcatcgtga aaatttgtgc ttttagcttg tatttctcat
    23101 aaatccatga taatttatta atgaagacgg ttaaatagtg atacagtttt attcactgtt
    23161 tcaatcgcag aatgaagaga ttttcttata gatgagagag gaatgtgtga caaatggcaa
    23221 acaaaaaagc accgatcgac ttccaagcac tgctagatga agtcaatgca gatttcccag
    23281 tatatcaagc acttgatcaa gatggaaacg tagttaacaa agatttagta cctgatttat
    23341 ccgatgatga actcgttgaa ttaatgactc atatggtatg gtctcgtgta ttagaccaac
    23401 gttcaacagc gctgaaccgc caaggacgcc taggcttttt tgcaccaact gctggacaag
    23461 aggcaagtca gctggctagt gcttacgcat ttgataaaga agatgttctt cttccaggtt
    23521 atcgggatgt acctcaacta gtaaaacatg gtttaccttt atctcaagct tttttatggt
    23581 ctcgaggaca tgctgcaggt aattcttatc cggaagaatt gaaagctcta ccaccacaaa
    23641 ttatcatcgg tgcacaatat gtacaagcag ccggtgttgc attaggtttg aagaaacgaa
    23701 acaagaaaaa tgtcgtcttc acttatactg gtgatggcgg ttcatcacaa ggtgattttt
    23761 acgaagcaat caatttcgct ggcgcttacc atgcaaatgc cgtattttat atccaaaaca
    23821 acgggtatgc gatctctaca cctcgtgaaa aacaaactgc agcaaaaaca cttgcacaaa
    23881 aagctgtcgc agctgggatt cctggtattc aagtcgatgg aatggatccg cttgcagtat
    23941 atactgtatc taaaatggca cgggaatggg cgatcagtgg aaatggacca gtcctaatcg
    24001 aaacactgac ttatcgttat ggaccacata cactatctgg tgacgatcca acccgctacc
    24061 gtacaaaaga cacagatgac gattggcaga aaaaagatcc attgatccgc ttccgtaaat
    24121 atttgacgga aaaaggactt tggtctgaag aaaaagaaga acaagtcatc gaagcaacta
    24181 aagaagaaat caaagcagct attgctgaag ccgacaaagt accaaaacaa aaggtttcag
    24241 atttcttgaa aaacatgttc gaagtatctc cacaatcaat caaagaacaa attgcaattt
    24301 atgaagcgaa ggagtcgaaa taatcatggc acaaaaaaca atgatccaag caatcacaga
    24361 tgccttagca cttgaactag aaaatgacga gaatgtcgtt gtttttggtg aagatgttgg
    24421 gaaaaacgga ggagttttcc gggcaactga aggattgcag gaaaagttcg gagaagaccg
    24481 agtattcgat actcctttag ctgaatctgg aatcgcagga ttgagtttcg gtcttgcgtt
    24541 agaaggattt cgtccagttc ctgaaatcca attctttggt tttattttcg aagcaatgga
    24601 cgaagtagta gctcaaatgg ctcgtacaag atatcgaatg agcggcacta gaaatctacc
    24661 catcacaatt cgttcgccat ttggtggcgg tgttcataca ccagaattgc attcggataa
    24721 tttagaaggt ttgatcgctc agtctcctgg tattcgagta gtgattcctt ccaaccctta
    24781 tgatgcaaaa ggactattga tttcttctat tagaagtaac gatccggttg ttttcctaga
    24841 acacatgaaa ctatatcgct cattccgaga agaagtgccg gatgaagctt acgaagttcc
    24901 tttggataaa gcagcagtta ctcgtgaggg aacagatgta tctattatca catacggagc
    24961 aatggtgcgt gaagcaatca aagcagcaga caatcttgca aaagaaaata tatctgttga
    25021 aatcattgat cttcgtacag ttgcgccatt agatgtagaa acgatcattc aatccgtgga
    25081 aaaaactggt cgcgtagttg ttgtccaaga agcacaacga caagcgggcg ttgccgcgca
    25141 agtagtttct gagatctcag aacgcgctat cctttcatta gaagccccaa tcggacgagt
    25201 ttctgcacct gatacagtct tcccatttgg acaagcagaa aatgtctggt tgccaaatgc
    25261 aaaagatatc gaagacaaag taaaagaaat cgcggaattt taagaaaaga agggacgaaa
    25321 caaagtcatg gcttatcaat ttaaattgcc ggatatcggt gaaggaatcg cagaaggtga
    25381 aatcgtcaaa tggttcgtca aaccaggaga tacgatcaat gaagatgata cattactaga
    25441 agttcaaaat gacaaatcag tagaagaaat cccgtcacct gttacaggaa cggttaaaaa
    25501 tgtgattgtt ccagaaggta ccgtagcaaa tgttggggat gtattagtag aaatcgatgc
    25561 accaggacac gaagacaatg aaggggacag tggtgtagcc gcagaatccc aaactccagc
    25621 taaaccggct gctgaaccca ctgttgatac agaatcagct ggatcgtcaa gcgaaggagt
    25681 cttccaattt aagttaccgg atatcggtga aggaatcgca gaaggtgaaa tcgtcaaatg
    25741 gttcgtcaaa ccaggagata cgatcaatga agatgataca ttactagaag ttcaaaatga
    25801 caaatcagta gaagaaattc cgtcacctgt cacagggaca gttaaaaacg tgattgttcc
    25861 agaaggcact gtagcaaatg ttggggatgt attagtagaa atcgatgctc ctggacacaa
    25921 tagtgcaccg tcaactagtg cgccatcagc tgaagcacca aaagaaaaag tggaaacatc
    25981 aggttcagca agtgtcgttg aagctgccga tccaaataaa cgtgtattgg ctatgccatc
    26041 tgttcgtcaa tttgcccgtg aaaaagatgt agatatctca caagtaactg caactggaaa
    26101 aggtggcaga gtaacaaaag aggacatcga aaacttcttg gcaggtggtc caagcagtgc
    26161 accagcgaaa tcagaagcgc cagaagcggc agcaccgaaa gaagcagctc ctgcagcaga
    26221 aagcaaacca gctgcaccag caaaaccatt caagtccaac ttaggagact tggaagaacg
    26281 tgtagcaatg acgccaacac gtaaagctat cgctaaagca atggtcaaca gtaagcatac
    26341 agctccacac gtgacattgc atgatgaagt agaagtgtct aaactatggg ataatcggaa
    26401 acgatttaaa gaagttgctg ctgcaaatgg tacgaaactt actttcttgc catatgtcgt
    26461 gaaagcttta acagcgactg ttaagaaata cccagtattg aatgcatcta tcgacgatgc
    26521 aaaccaagaa atcgtttata aacattacta caatatcggt attgcaactg atacggatca
    26581 cggactatat gtaccaaatg tgaaagatgc agaccgcaaa ggaatgtttg ctattgcaga
    26641 cgaaatcaat gagaaagcaa aattagctca tgacggcaaa ctatctgcag aagatatgcg
    26701 caatggaaca attacgatca gcaatatcgg atctgtaggt ggcggttggt ttacaccagt
    26761 catcaactat ccagaagtag ctattttagg tgtaggaacg attgcacaac aaccaatcgt
    26821 aaatgctgaa ggcgaaatcg ttgtcggtcg tgtgatgaaa ctgtcattaa gtttcgatca
    26881 ccgtatcgta gatggagcaa ctgcgcaaca agcaatgaat aatatcaaac gtcttttagc
    26941 tgatccagag ctattaatga tggaaggatg ataaacaaat ggtagttgga gattttgctg
    27001 tagaattaga tacagttgta attggtgcgg gacctggtgg ctatgtagct gccatccgcg
    27061 ctgctgaaat gggacaaaaa gtagcaatca ttgaaagaga gtatattggc ggtgtttgtt
    27121 tgaatgtcgg ctgtattcct tcaaaagcac tgatagctgc aggacaccat tatcaagagt
    27181 cactagattc tgaaatgttt ggagtaacta gtgaaaacgt caaactagat tttgcaaaaa
    27241 cacaagaatg gaaagaaaac aaagttgtcc atacgttgac ttctggtgtt ggtttcctat
    27301 taaaaaaaca taaggttgaa acaatcgaag gagaagcgtt cttcgtagat gatcacacac
    27361 tacgcgtcat tcatccagat tcagctcaaa cttattcgtt caataacgca atcatcgcaa
    27421 caggttcccg tccaatcgag attccaggat ttaaattcgg aggacgtgtg ttagattcta
    27481 ctggcggatt agcattgaaa gaagtaccta agaaatttgt gatcatcggt ggcggtgtga
    27541 ttggtgccga attgggcgga gcgtacgcaa acttaggagc agaagtaacg attcttgaag
    27601 gctcaccaca aattttacca acttacgaaa aagatctagt aaaattagta gaagatgatt
    27661 tcaagaaaaa aggcgtaaca gtcgtaacga atgcaatggc gaaagaagca gtcgataacg
    27721 gtgacagcgt gacagtgaaa tatgcagtgg acgggaaaga agaatccgtt actgctgatt
    27781 atgtgatggt cactgtaggt cgtcgtccga atacagatga tatgggctta gaacaagcgg
    27841 gtgtcgaagt aggagaacga ggattgatca cggtggataa acaaggacgt acgaacgtac
    27901 ctaacatcta tgccatcggt gatatcgttc caggggcggc attagcacac aaagccagtt
    27961 atgaagcaaa aatcgctgct gaagcaatct ctggcaaaaa agtagctgta gattataaag
    28021 caatgccggc agtagccttc actgatcctg aattggcttc tgtaggtatg acgatcaaag
    28081 aagcaaaaga tgctggtatc gaagcaaaag catataaatt cccattttca gggaacggtc
    28141 gggcattatc gcttggtaaa acagaaggat tcatccgtct agttacgacg atcgaagata
    28201 acgtgcttat tggcgcgcaa atcggtggag tcggcgcaag tgatatggtc tctgaattag
    28261 ctttagcaat cgaatcagga atgaatgctg aagatatcgc cttgacgatt catcctcatc
    28321 catctcttgg cgaaatcgtc atggatgctt cggaattagc attaggttta ccaatccata
    28381 tttgatttga ataatacagg cgaaacgcaa ctgaaaaatc agttgcgttt tgttttttag
    28441 aattatcaat aatattatta tgtaaactta aaaatatgac aacttcttgg tttattacca
    28501 cttcctatgc tacactgaag aggaatatga aataggagag ttgaagatgc aagaatatca
    28561 gtatccactt gatttagatt ggacaacaga cgaaatggtc attgtaatga agatgtggga
    28621 agatctggaa cgtgcgaatg aaaaagggat aaacaatgaa gcttttttga agacttatca
    28681 gcagtttaaa actgttgtca aatccattgg tgaggaaaaa cgattgggac gggaatttga
    28741 aaaagcttcc ggttattctt tatatcgtac agtgcagcaa gcaaaaaaaa atccaaacaa
    28801 aactttgaga atgaacgggt gagataaatg gaacagatga ttgatcatat caagtcctgg
    28861 cttgaagaag ctggtgagaa aatcaaatct tctcaacaaa cattaacaat ctcgcaaaaa
    28921 tcaaatcgaa cggatctagt aacaaatgtc gatcgaaaca tccagaattt tctaatcgaa
    28981 aaaatccatt cctttgatcc agaggcgaaa atattggcag aagaagaagg gtgtaatcaa
    29041 ttatcggatc tcgatggaag agtctttatc atcgatccta ttgatggcac cttgaatttt
    29101 gtgattgaag gggaaaattt ttgtattatg ctcgctgttt atgaatccgg cgttggaaag
    29161 cttggtttca tttatgacgt gatgagaaat gaactttttt ggggtggaaa aggaataggc
    29221 gtgtataaaa atgatgagcc attgcctaga ccagcaaata aatccttatc ggaaggctta
    29281 cttggtgtga atagttatct tttcggtcat aataaatatg gaatccgaga aattgcggaa
    29341 agcagcatgg ggacacgtat gtacggatgc gctggtcttg aactagtggc aatcttgaaa
    29401 ggaaaccaca ttgcttatat ttcaaacctt agcccttggg attatgcagc gggaaatgtc
    29461 ttattggaag agtttggtat ggtaacaagc ggtctttttg gtactccttt gacatttgaa
    29521 aaaagggaat actatttagc agggacttct tgtgcatatg cagaaatcgc agaccttttg
    29581 aaaaaagaag gctgaaaaaa aggtagaaat cattcacaaa aatgataaaa acgagcaaaa
    29641 gattaatttt ctcgaaaaaa tgaaaacatt ttactatatt tcatgaaaaa agtctgctat
    29701 aattagcagt cgagtaaaat ttgccctgtc ataaagaacc aataaaaaag gagttagtta
    29761 cattgaatta tagaaacgat atccgtaacg tcgcaattat tgcccacgtt gaccacggaa
    29821 aaacaacatt agttgatgaa ctattaaaac aatcagatac attagacgca catacgcaat
    29881 tgcaagaacg tgcgatggac tcaaatgcgc tagaaaaaga acgtggtatc acgattttag
    29941 ccaaaaacac agctgtagac tataaaggta ttcgcgtaaa catcatggat actccaggac
    30001 acgcggactt cggtggcgaa gtagaacgga tcatgaaaat ggttgacggc gttgtgttgg
    30061 tcgtagatgc gtatgaagga acaatgcctc aaacacgttt tgtattgaaa aaagcactgg
    30121 aacaacatat cacaccaatc gttgtcgtaa acaagattga caaaccttct gctcgtcctg
    30181 agcatgtcgt agatgaagtt cttgaactat tcatcgaatt aggagcagat gatgatcagt
    30241 tagactttcc tgtgatttat gcatctgcac taaatggtac gtcaagcttg tcagatgatc
    30301 cagcagatca agaaccaacc atggcaccta tttttgatac aattattgaa aaaatccctg
    30361 ctcctgtcga taacagcgac gaaccattac aattccaagt ttcattactt gactacaacg
    30421 attatgtagg tcgtatcgga atcggacgtg tatttagagg aacaatcaaa gtaggagacc
    30481 aagtagcatt aattaaatta gacggaacag ttaagaaatt ccgtgtaacg aaattatttg
    30541 gtttctttgg actaaaacgt ctagagattc aagaagcaaa agctggagac ttgattgctg
    30601 tctcaggtat ggaagatatc tttgtcggtg aaacagttac tcctgtggat catcaagatg
    30661 cgttacctat ccttcacatt gacgaaccaa cattgcaaat gactttctta gttaataatt
    30721 caccatttgc cggtcgagaa ggtaaattcg taaccgctcg taagattgaa gaacgtttga
    30781 tggcagaact tcaaacagat gtatccttac gagttgaacc aacaaactct ccagatgcat
    30841 ggacagtttc tggtcgtgga gaattgcatt tgtctatctt gattgaaaac atgcgccgtg
    30901 agggatacga attgcaagta tctcgtccag aagttattga aaaagaaatc gacggtgtaa
    30961 aatgcgaacc gtttgaacgc gtgcaaatcg atacaccaga agaatatatg ggtagtgtta
    31021 tcgagtcctt gagcttacgt aaaggtgaaa tgcaagatat ggtccataca ggaaacggac
    31081 aaatccgttt gacattctta acacctgccc gcggtttgat tggttattca actgaattcc
    31141 tttcaatgac acgtggttac ggaatcatga accatacttt tgaccaatat ctgccaatgc
    31201 ttcctggtca aattggcgga cgtcaccaag gggcgcttgt ttcgatcgat acaggaaaag
    31261 caacgactta ttctatcatg agtatcgaag aacgcggtac agtcttcgta gaaccaggta
    31321 cagaagtata tgaaggaatg attatcgggg aaaacagccg tgataatgat ttgactgtca
    31381 acatcacgaa agcaaaacaa atgacaaacg tacggtctgc tactaaagac caaacatctg
    31441 tcatcaaaaa accaaaacaa ttgacgttgg aagaatcttt ggaattcttg aatgatgatg
    31501 aatattgcga agtaacacca gaaagcattc gcttgagaaa acaaatttta gagaaaaatg
    31561 ctcgtgaaaa agcatctaaa aagaaaaaat aatctgtaaa aggatgaaga gagaaaccag
    31621 cttgttataa aaaatagctg gtttcttttt ttgtccaact cttttctgtg gagaagtcat
    31681 ctttgtcaat ggacataaat tcagaaaata cgccgaaaga cgtttaaaag acttttaaaa
    31741 aacttatttc tagagagttt ttgtttcata ataagataat gtttcacgaa aggagatcaa
    31801 cttgtccttc gaagaaaatc gaagtaaaat ggcaagagaa aggagcggga agatgaacga
    31861 cttattaaaa caatactttg gctatgatga gtttagacct ggtcaaaaag aaattatcca
    31921 gaaagtcatt gatcaggaaa atgtattagg aatcatgcct accggaagtg ggaaatcaat
    31981 ctgttaccag cttccagctt tactattaga tgggcttact gtggttgtgt cccctttaat
    32041 ctctttgatg aaggatcagg tggacgcggc gaatcaatta ggtatacccg ccacttttat
    32101 caatagctcg ttagatggtt acgaaacagc tagacgcttc caagaaatcg atagacagca
    32161 gtaccgttta ctttatatcg ctcctgaacg ttttatcatg ccggatttta tccaagcaat
    32221 gaagcgatgg aacgtccgta tgatcgctat tgacgaggca cattgtatct ctcagtgggg
    32281 gcatgatttc cgcccaagtt atttacagat ggcgaaccag ctagatcaac tgccaaatcg
    32341 tcctgtaatt gttgctttga cagctacagc gactgtgcaa gtagctgctg acataaaaag
    32401 acttttaaaa attccagaaa acaaccatat tcagactggt tttgaacgag aaaatctacg
    32461 atttcaagta attaaagatc aaaaaaaaga acaatatcta atcgaatatt taaagatcaa
    32521 caaaaatcaa tctggtatca tttatgcagc aacgagaaaa gaagtagacc gtctctatca
    32581 tttgcttaaa aaattcgatt tttccgtggg tagatatcat ggtggtctaa atgagaatga
    32641 gcgaacagaa atgcaagaag cctttttata cgatcgcttg cagctgattg tagcgacaaa
    32701 tgcatttggt atgggtataa ataaaagcaa tgtccgtttt gttatccatt atcaaattcc
    32761 tggctctcta gaagcatact atcaggaagc tggtcgggcg ggaagagatg gtctttccag
    32821 tgaagccatc ctgcttttct ctcctcaaga tatccaagtc caaaagtttt ttatccagca
    32881 gtcccaaaga gaagaagggc aaaagcaaaa agaatatgaa aaattaaaag cgatgacaga
    32941 atacgtgtat attgagtcct gtcttcagca atacatccta aactattttg gcgagacaag
    33001 cagtccgtgc aaccgttgtg gtaactgttt agatgacaga gaaatagtag aagtaacgac
    33061 agaagcacag atggttcttt cttgcttaaa acgtatgggt gagaactatg gtaaacaaat
    33121 gctgatgaaa gtcttagcag gatcgaaaga acaaaagctg caagctttag gttttggaca
    33181 tttatctacc tatggactga tgaaaaacca atcgcaaaaa gaaacgatgc agttaattga
    33241 atatttgata tcgaatggct atcttctgac catcaatggt gagtatcctg ttttgaaagt
    33301 aacagaaaga gggatacaag tattgaaagg acaagaatct gtttatcgaa aggaacccaa
    33361 gaaagtccag cagctatcgg atgaagaaac cgatacacta tttgaagtgc tgcgggaact
    33421 gcgaacggat ctagcatcag aagcaggcgt tcccccgtat gtcgtatttt cagattccac
    33481 attgaaagaa atgagccgaa tacgtccatc aagcagattg gagatgcttc agataaaagg
    33541 agttggccaa agcaagcttg ataaatatgg cgaagccttt ttatctcgga taaaaaatgc
    33601 ggactctaac gttctggata agtagaaaga acgaatacgt aaaaatgaat aaaaacaact
    33661 ggttaaatct gttttttttg ctccttatga aaatcaaata tgttataatt aaggaattag
    33721 aatgggaggt aagcacagat ggattctttg tcgaaaaaac ttgcgatcca agtattaaat
    33781 gatgaagcag aacggatcaa acgattaatc cgaaatcaaa acaacagtct ctgtatctca
    33841 caatgcaaag ccttcgaaga agtggtagat acacagatgt acggcttttc ccggcaagtc
    33901 ggttttgctg tccgtatagg agtaatcgga aagaacgagg gccagctgat gttaagtgag
    33961 ctagaacgag aattgaatca gttatatagt gaggtttacc aagaaattta tgataaaaaa
    34021 gaagttggca aggaggaata gacttgccta agaaagtgaa aaaaaggcat ctattagact
    34081 atagcatctt gattccctat ttaattttat gtgtattggg attgatcatg gtatatagtt
    34141 ctacgtcgta tctattatta gaaaacggac aaaatccgtc cgcatcagtc attaaccaga
    34201 gtattttttg ggtgcttagc ttgattgcta tcgcactact ttataaaatg aaaacagatg
    34261 ttttgaaaaa ccagcgtttg atcatggcag ccatcgcagt tttgacgatt ttgctgctga
    34321 ttgttgtgtt ttttggtaag gagatcaatg gggcgaaagg ttggctgcaa attgcaggat
    34381 tctcgatcca acctgccgaa tacctaaaaa tcatttctat ctggtacctg tctctgactt
    34441 tatctaaaag acaaaacagt gtacaaaaag attttcttgg gactgtgaaa cgtccacttg
    34501 caatggttat cggacttact gcattagtcg ctattcttcc cgattttggt aatgcggcag
    34561 ttatcttttt gattattttg gttctgcttt tagccagcgg agtcaattat gtgtatactt
    34621 tgattgtagg agtaggaggc ttttgtctaa gtacttttac gatctggctg atcaatatca
    34681 caaacggaaa gatcttaccc ggacgtttac agtatatcta taatcgattt gctatttacc
    34741 aaaatccttt ctcagacgaa ttaaataaag ggcatcaact agtcaacggc tactatgcca
    34801 tgttcaacgg aggactattt ggcaggggat taggtaacag tatccagaaa aaaggatttt
    34861 tacaagaagc acaaaccgat tttatttatg caatcgtagt ggaagaactg ggagtgatta
    34921 tggggatttt gatattagcg ttgctattct ttatgattgt gcgcattgtc cttgtaggta
    34981 tccgttcaaa agatccgttc aattcgcttt tgtgcattgg gatcggcgca atgtttttga
    35041 tccaagtatt tgtcaatctt ggaggaatta ctggcgttat tcctttgaca gggatcacgt
    35101 tcccattttt aagtcaagga ggctccagtt tgctgatgct ttcgatttgt gtcggctttg
    35161 tcctcaacat cagtgcggat gaaaaacgca agagcttagg tttataataa aaaaagatgt
    35221 aggagtggtt cgatgaaaaa agttttagtt gctaacaggg gtgaaatcgc tgtacgtgta
    35281 tttcgtgctt gtacagaatt aggaattaaa actgttggaa tctatgcaga agaagatgaa
    35341 tattccgtac accgtttcaa agcggatgaa gcatatttag taggacaagg aaaaaaaccg
    35401 attgatgcgt atctagatat tgaagggatc atttctatcg cgaaagaatg cggagctgac
    35461 gctattcatc cgggttacgg tcttttgtcg gaaaacttga attttgcgca acggtgcgaa
    35521 gaagaaggca tcatttttgt tggacccaaa ctgcatcatt tagatatttt tggagataaa
    35581 atcaaagcaa aagctgcagc tatcgaagcg gggattgctt cgattccagg cacagatgga
    35641 ccaatcgctt ctatagacga tgccttggag tttgcgaaac aatacggtta tccgattatg
    35701 atcaaggcag ctctaggcgg cggcggacgc ggcatgcgtg tagctcacga tgaaaagagt
    35761 gcaagagagg gctacgaacg tgcgaaaagc gaagcaaaag cagcctttgg tagtgatgaa
    35821 gtgtatgttg aaaaatacat cgctaatcct aagcatatcg aagtacagat tctcggggat
    35881 acgcatggaa acgtcatcca tctttttgaa agagattgtt ctgttcagcg ccgtcaccaa
    35941 aaagtagtag aagtagcgcc ttgtgtctct atgaatgaac agcaacgtca aaaaatctgc
    36001 caggcagctg tccaattgat gaaatatgtc gggtatgtca acgcaggtac agtagaattt
    36061 cttgttgaag gagatgattt ttactttatc gaagtcaacc ctcgcgtcca agtggaacat
    36121 acgatcacag aaatgattac agatattgat atcgtaacaa cgcaactgtt gattgctcaa
    36181 ggtttggatc tgcataaaga aatcggattg cctcagcaag aaggaattaa attaaatggt
    36241 tcagccattc aatgccgaat cactacagaa gacccgttga ataacttttt accagacaca
    36301 gggaaaatcg atacgtatcg ttcacctggt ggttttggcg tacgtctgga tgtcggaaat
    36361 gcttacgcgg gctatgtagt gacaccgtat tttgattcat tgctagtaaa agtatgtacg
    36421 catggtgcta cctttgaaac agccattcag aaaatggaac gttgcttgaa agaatttaga
    36481 atccgtggag tgaaaacaaa cattccattt atgctcaatg tcatcacaca tcctgaattc
    36541 caatcaggaa atgcaaaaac aaccttcatt gatagtacag caacattatt tgaatttcct
    36601 cgactacgag accgcggaaa caaaacgatg aaatatatcg gtgaaattac tgtgaatggt
    36661 tttccaggta tcgaaagtgg cgaaaaacca ttttatgaag aaccacgtat gcctaaagat
    36721 ctaatcacaa gaactgatta cgtaacggct aagaatgtat tagatgcgaa gggtgccgat
    36781 gctttggtcg aatggatcaa aggacaggaa aatttgttgt tgacggatac gacatttaga
    36841 gacgcccatc aaagtctgct agcaactcgt gttcggacaa aggatttcaa gcagattgca
    36901 cgtttgactg gagaaggtct tcctgaactc ttttcaagtg agatgtgggg gggagcaaca
    36961 tttgatgtgg cttaccgctt tttgaatgaa gatccttggc aacggttgag aaaaattcgt
    37021 tctttaatgc ctaatacgtt gctgcaaatg cttttcagag gttcaaatgc cgttgggtat
    37081 tctaattatc ctgacaatgt attggtggaa tttgtcaaag aagcagcagc gcaaggaatc
    37141 gatgtatttc gaatctttga tagtttgaac tggactccac aaatggaaaa aagtatccaa
    37201 gctgtacggg atactggtaa aatcgcagag gcagctattt gctatactgg cgatatcaac
    37261 gatccaagtc gggcaaaata caatgttcag tattataaag acatggcaaa ggaactagaa
    37321 caactgggtg cgcatatcat tgcaatcaaa gatatggctg ggctgcttaa accgcaggca
    37381 gcttatcgtt tgattagtga attgaaagaa acgacagatc tgccaatcca tctgcatact
    37441 catgatacca gcgggaatgg aatcatcact tattctgctg cttcaaaagc aggagtagac
    37501 atcgttgacg tggcaatgag tgcaatgagt gggaatacta gtcagcctag catgagcagc
    37561 ttgtattatg cactggtcaa tggtccacgg ctgccagaaa tcacgattga aaatgcacag
    37621 aaattaaacc attattggga agatgtgcgc atgtattaca aaccgtttga aaacggcttg
    37681 aatgctcctg aaacagaagt atatatgcat gaaatgccag gaggacagta ttcgaatcta
    37741 cagcaacagg caaaagctgt cggattaggt catcgctggg atgaaatcaa acaaatgtat
    37801 catactgtca acttgatgtt tggcgatatc gttaaagtaa ctccatcatc taaagtagtt
    37861 ggagatatgg cactatttat ggtccaaaat gatcttacag aagaagatat ttatgaaaaa
    37921 ggcgaaacac taagtttccc tgaatctgtt gtgactttct tccaaggaga actagggcaa
    37981 cccgttggcg gatttcctaa aaaattgcaa aagattattc ttaaaggcag acctgcattg
    38041 aatgaacgtc caggtctttt ggctgaatca gtcgacttca acgaagtaaa aaaagaattg
    38101 gcagaaaaaa ttggctatga accaaaacaa gacgaagtat taagctattt gatgtatccg
    38161 caagtctttt tggactatca aaaagcatat aatcaatttg gcgatgttac attactggac
    38221 acaccaacat ttttccaagg tatacgtttg ggtgaaacaa tcaatgtaca aatcgaacgc
    38281 ggaaaaacgc ttatcattcg tttagatgaa atcggagaac ccgatatcga agggaatcgc
    38341 gtactgttct tcaatttgaa tggacaaaga cgtgaaatca ctatcaaaga taattcgatc
    38401 atcagtacgg tccaaacccg attgaaagct gaaccgacaa accgagaaca aattggagca
    38461 acgatgtctg gttctgtttt ggatgtatta gtgaaaaaag gcgataacgt taaaaaaggt
    38521 gatacgttga tgattactga agcgatgaaa atggaaacgg ccatcgaagc acgttttgac
    38581 ggagaagtcg cacatgtata tgtgtcttca ggagacacta tttcgtctgg tgaccttttg
    38641 attgaagtga ctgagaaata ataagcgaaa ggtggggaaa catgaaaaga ctgggtttgt
    38701 tttggctgat tctgctatta gttattgtgg cattctacat ggaaccagtc ttgtttccgc
    38761 caaaacttga agtgaaggaa aactctgatc aacaaatatc aaaccaaatg acaacgtgga
    38821 aataccagga gcttaaagca actggttttt ctacttatat cggaaaaccg atcgatcagc
    38881 tggaaaagga ttttggccaa gcctatgatc gattaactag cggatttggt tttgaaacaa
    38941 gatattatga aaataaagct agtcatctca catttgaagc gaacatccaa gacagcagag
    39001 tcacaactgt taaagtactg caaacagggc ctgctgatat cgcgccgttt tatttaggga
    39061 tgacgatgca agatcttacg aaaatcacta ctatctatac taatttcact tttgagtacc
    39121 atgatacaga agttggaatc gaactaatgg aagaggatat gaattatcgt ccgctaattg
    39181 cttttgataa cgacactttt gctattttat tttttgatca aacaacaaac ggcctatttt
    39241 cagttgtgta tttagataaa gatagtcttt tgaaactatt gccatatcaa gtgtttggtg
    39301 aaggccttcc acattatcaa gcagataaat cggctgattg ggaatcaatc aatcgcgtta
    39361 aagaacgaaa aagtacgact ttattaaata tgcttagaag agaagacgaa cttcccatat
    39421 acaatcaaac acttgccttt caaaaccaca gtcagctgct actacatgat tttttgacaa
    39481 ggcctgagga aatattgtca gaggaacgta tggctgattg gcaaaaatcg ctaggcagtg
    39541 ctcaaacgac agtgaaattc tcactgacga atgatgaatt ggagaagtta atcagtaaac
    39601 aaaaattaga aaatactagt gggctattta ttcatccggc gattgacgct actttttcgt
    39661 ttttatattg gtacagcgat ccttacaacc atgaccgttt catggacccg ggaacggatt
    39721 ctgtaggcat tgctttttct aaagaaaata tgttagtctt attgcaagaa gaaaacggag
    39781 aaagtagtga tagcagtgat cgttaacgaa gagctgtttc aactggagga tcaatgcctc
    39841 caagtcgctg aaatgataaa aaagagtaaa acgatggctt cttatcttga acataaacag
    39901 tcaatggaag aatctgcaaa agtttgccag ttgaaagaag cgttcttgtc taagaaagaa
    39961 gcatttgaaa atgtagcggc atatggtgag tatgcacctg attatcgtga aaaaaaacga
    40021 gctgttcgaa aagcaaaaag acagcttgat atggatgagc atgttgcagc tttccgatat
    40081 agtgaaacac agctgcaaag tctgttggat caaattgtcc aagtacttgc cgaagaagtt
    40141 tctaatgaaa tcaaagtaga tgcaggtagc ccgttttttg aaacgaaaaa acactttgga
    40201 tgcggaggta attgtcatgc aattagacaa tagtgaattt gaaataacaa aacgacgcgg
    40261 gctgatcgta tgggtctaca gcttaaaaca attaaagaat ctgaaaaagt tcggcttgtt
    40321 gcattatgtc tcaagaagaa tgaaatatgt cgtgctttac ttaaatgaag agacattgga
    40381 agaaacagaa gaacgaatcc gtaaattaca ttttgttcga aacgtagaac gttcttaccg
    40441 accggatatc gaaatgaatt ttgccgaaaa aataggaaac aaaacagtat taaaagacga
    40501 aggtttcgaa attgaagagc taaatacaga aatccgatta gctgaacatc tttaaaaatc
    40561 tcttatgagc agtttttaaa taaaaaataa cttggataac gatcgatttt tgatcattgt
    40621 ccaagtattt ttttggtata ctagtaccag taccatttct aaggagtgag tagatgcgga
    40681 taatatcagg aaattatggc gggcgccgtt taaaaagttt agcaggggcg aacaccagac
    40741 caactacaga taaagtaaaa gaatccatat tcaatatgat tggaccatat tttgatggag
    40801 agacagtatt ggatctgttt gcaggaagcg gtggtttagc tatcgaagca gtatctagag
    40861 gctgcagtca tgcggtatgc gtagacaaaa attaccaagc gctaaaaatc atcaaagaaa
    40921 acatcgaaat tacgaaagaa ccagagaaat ttaccacaat aaaacttgat gcggacaaag
    40981 caatcgaacg gctagcagcg gagaaacaac aattcgacta cttgtttctt gatccgccat
    41041 atgcaaaaca aaaaataatc gatcaaatcc ataaaatgga agaactggga cttttttcta
    41101 aaaccgcagt tatcgtatgc gaaacggata aaacagtcga attgccagaa actgtggctg
    41161 gattccatca aataagaaaa cagatttatg gcataacggc cgtaactatc tatagaaaag
    41221 agggaaatca atgaaacgtg cattattccc aggaagtttt gatcctttta caaaaggtca
    41281 cttagatacg gtggaacgtg cggctaaatt attcgatgag gtagtaattg gtgtttttat
    41341 caatacttca aagaaaagtt tgtttccccc agaagaaaga atgacattga tcacaaaagc
    41401 tgtttctcat cttcctaatg taaaagtcat gcatcaagaa aatcaattga cggtagaaac
    41461 agcaaaagag attggtgcag atgcgttgat cagaggcata cgaagtatca aagactttga
    41521 atatgaacga gagattgctc agatgaatca tcatctatat gatgaattgg aaactgtctt
    41581 cttattagca aaaccagaat atagtcacgt gagttccagt attttaaaag aagtactgca
    41641 ctttggcgga gatgtgagca gctacttacc gccagtgatc aacgaagctt tagctggaaa
    41701 gcgtgaatca aatgaaagct aaacaatggt tgaaaacagt actgattatc atatttggaa
    41761 tgttgatcat tggatttgta gtagttccct tgccgtatta tgtagaatca ccgggagcca
    41821 cgatcgatct gaaagaacta attacggtca atgataagga agataaaggt tctgggtctt
    41881 tctctcttac ctctgttggt atcaggcaag ctacaggttt cttagcttta aaagctaaaa
    41941 tgaccccttt tgaagaattg atcagtgaag aagaattgac tggtggggcg acaaatgaag
    42001 aatataatca aatgcaacag tattatatgg attcttccca aaatgcagca atcgaacaag
    42061 cgttaaaact tgcagacaag ccttataaaa tggaattcaa aggcgtatat gtcatgagtg
    42121 tagagaaaac atcgaatttc tttggcaagc tttcagttgg agatacagta acaaaagtag
    42181 acgggaaaag ctttcaaagt acagaagcat ttatggatta tgtaaaaagc caaaaagttg
    42241 gacaaacaat cgaaatcagt tatttgcata atggtgaaga aaaaacagct tctggtgatc
    42301 tgatcgagtt accaacagat aaaaaggcag gaataggtat cacgcttact gaccataccg
    42361 agatcgaatc agatacagat gttcgtatta attctggctc tatcggtggg ccatcagcgg
    42421 gattgatgtt cactttagaa atctatgaac aagtcactgg taaaaacttg cgacatggta
    42481 agcaaattgc aggaactgga acgatcaaca gtgaaggaga agttggccga atcggaggaa
    42541 tcgataaaaa agtggcaagt gcggataaag ctggcgtaga gattttcttt gcaccagatg
    42601 atacgatttc agacgatgtt aagaaagaat atcctgaaat aaaaaccaac tacgaagaag
    42661 caaaagctgc cgctaaaaaa ttgaattcct caatgaaaat cgtaccagta aaaacagtac
    42721 aagaagcgct tgactatcta gagaaaatga aatgaaacta aataattaaa gaggggttgt
    42781 gacacgagtt ctgtcacaac ccctcttttt cgtcaaaaat cttcacgata aaaataaaaa
    42841 caaaagaaaa aattgacgta attagatgtt gaagggacga ttttgccaga gctcactgtt
    42901 tcttcaattt taaatgaaag gagtaatgaa tgatttttac tggtcattct ttgaaaaaag
    42961 aacaatgata gaaaaaatca gcaagaaaat actagcttca cccaaattga tcatttggat
    43021 gtctatgata gttcttatct tttgtatcgc aagtggtttt ttattatcaa atttgctatt
    43081 ttatagagaa acagaagaga ctgctgcaaa agaaatactt tcttcgttta gttccagtgg
    43141 agaagatcca tcagctgaag gaaacgatgt agaagaggat gctcgtccaa aggtcatgta
    43201 caccgatatc aaaggaagtg tgaaggagcc tggtatctat tccttttctt cagaagaacg
    43261 ggtctatgat gtactaaagc gtgcaggtgg attattagaa gaagcggata gcgatcgaat
    43321 caacttttct gcgaagatag aagatcagca agtcctatat atccctgctg taggtgaaga
    43381 gctgccagaa catcttgatc agttggcatc ctcggaagga aaacagccta cagcagattc
    43441 cgagcctccc aaaataaata tcaatacagc cactccatca gaacttcagc agattcctgg
    43501 gatcggatca gtcaaagcgc aagaaatcat tcgatttaga gaagaaaacg gatccttcca
    43561 gaaagtggaa gacctgcagg agatttctgg tatcggtgaa aagacagttg aaaaactaaa
    43621 aaacttcgtt acaattaaat agaatgattc aaaatcgact ggcacgagca ataaatggac
    43681 gctaatggat actaagaata atccaattct aagagcttgg caggacgagg aggtagtatt
    43741 tttggatagg aaatagcttg attgttcgca aagaaacatt aaaaaaacca atgctgaatg
    43801 tctatctcca aaataaaata tctgggattc atattatgaa tacggctgtc agcggcaata
    43861 acagtcaagc tctacgagaa cgctttgcca aagatgtact tagctataca gcagataaag
    43921 tatttattct cattgggacg aatgatctag cagagcataa acaactttct aaagaaacgt
    43981 accaaaaaat ctgcagtgga tgatagttca gctgaaaaaa gactatagtt ctgatcatgc
    44041 tttctttatc acgccaccag cagtcgatga gacaaaacaa aaatatcgga ataacaagtt
    44101 gatcaaagaa tatatctctg ttctcacaga agtagcaaaa cgccatgatt gtgaagtatc
    44161 gatttttata cggaatttct tgaacaaatg gattcgaaga atttttataa tgggctaatg
    44221 gatgacggac ttcatttcgg cagtgaaggg taggatcttt tgtcagacag gatgattcgt
    44281 tatatttaaa gaatattttg tttaagcaat gagtactttt taatcaactt gaaaaaacgg
    44341 aggaatataa aacatgttag aaaaatcttc aaaagcatgc gatacgaata aagaaaaagt
    44401 tactgataag tcacataatg aacgcattcc ttgggaccag tactttatgg ctcaggcagt
    44461 actgttatct ttacgtagta cgtgtacacg tttagaagta ggagcgacac tcgttcgaga
    44521 aaaaaggatc attgctggcg gctataatgg agcagtcagt ggagatgtcc actgcataga
    44581 tgaagggtgt tacgtcgtgg atggacactg cttgcgaacg atccatgcag agatgaatgc
    44641 actcctacag tgtgcaaaac ttggtatccc gacggaaggt tcagaaatct atgtcacaca
    44701 ttttccatgt ttggcctgta caaaggcttt gttgcaagct ggtgtgaaag ggatcaatta
    44761 tctccatgac tatcgaaatg atccttatgc ccaagcgttg atcgaacaat taggtgtatc
    44821 tgtacaccaa gttgctttag actcacagca tttttcaaaa cttcaaaatg aattaacagg
    44881 aaaacatgtc tagcgtttta gaaaggcatg ttcgaaatcg gttgattttt ccggcaatta
    44941 cgtcgatgat tatctgtttg ttgtattaca ctgacaattg gggttatcgt ttgcttcttg
    45001 ccggaatttt tttatggttt tcgctaaaag aaggacgttt tatcgcgtac ttgtgtattt
    45061 tgtgtagcat aacggtatcc atttcttata ggctacaaga gtattcattt ttagaggaaa
    45121 aaacaacatc tgcgcaaatt actgtattta cagatacgat tcgtgcaaat ggtaattttt
    45181 tgacaatgga aggaaggtta tcagagaata aacaaaagct ccagctttct tatcaagtaa
    45241 acacagaagc agaattgaaa acatggctta acttccgagg aaagggaata gaattgactg
    45301 ctgaaggcga gttcatctct ccagcaaaaa agcggaatct ttataatttt gaccaagaag
    45361 cttacttcag gaaccataga atttctggac ggttccaaat tcaaaagatt gaacagatca
    45421 ccatgcaaaa tcactggcga aactggcttc agagaaaaag aggatctttt atctcctttg
    45481 tccaatctga atttccgcaa aaaacaagtg tatatattaa ttctttatta tggggctata
    45541 aagatgcagg attcagagaa ccagaagaaa tttttaggga gagtggtttg ctgcatctgt
    45601 tcagtctatc gggtctacac atccaatttt atttagggtg gctgtattat ttgtttcgac
    45661 gtatcggatg gccactacac gtcagtatta ttccgttgag tctactaact atctgttatg
    45721 tttctattgc aggaagttct atttctgttt tgcgtgctag tttgctgttt ttattgcgat
    45781 tgctagtcaa attgctgaat aagcattatt ccaccatgga cttatttgca gttgtctttt
    45841 ggcttctttt actatttgat cctcgatttc tttttcatgc gggtggacag cttagttttt
    45901 tcatgagttt tttgtttatc ctgatttctt ttgatggaga ttggttgaaa aaaacggcct
    45961 ctcacgtcct gtttactatg atcacgatgc cgttgattgt atggcatttt tatgagtggc
    46021 ctattttagg tagtcttttt acattactga ttgcaccggt attcaagttt ctttttcttc
    46081 ctggtgtgtt atttctcaca ctcttcaatc gctggctgcc ggaaacttta cttttgctga
    46141 tagaagaggg attaatctta tttgagcgaa taatcgattt ttcttcaggg tcgtctctca
    46201 ttataggacg tttgcccctt gtgctatctg ggatgtatat tttcggatta ctgatttgta
    46261 tggataggtt gaaagaacaa cctgtgaaac acttgtttta tgttggtctt ttttctttta
    46321 tttttttgac tttgccattt ttacgctttt cttcaacgat cgcttttatc gatgtcggtc
    46381 aaggagacag tatctttttg caaagtcctt ttcgaaaaga aacgattttg atcgatactg
    46441 gaggtcagtt acactttgaa agagaaaagt gggcgcaagg tatgatacgt cctcctgctg
    46501 aaagaaatat cgttccatat ctaaaaggtc aggggataag tgtaatcgat aaactcatct
    46561 tgacacacga cgatacggat catgtgggag aattacccac gttatctcag cattttacta
    46621 tcaaaaaaat ttatatcggt tggggcgctg gacgaaatga gccattacaa aggcatttat
    46681 ctgaagctca aaaaaatggt actgagatca ttgaaatcaa acatggggac aggatcagcg
    46741 gttattatga tctttatgta ttgactcctt ttgaaaaggg agagggaaga aatgaagatt
    46801 cgattggtct atggatggaa tataacaata ggcgcttttt atttttagga gatttgaatc
    46861 aagcaatgga aaaacaattg cttttgattt atcctaatct gaaagccgat gtagtcaaat
    46921 taggtcatca cggtagccgt acgtcaagta acacagattt tctttcccat attgaagcaa
    46981 aacatgggat tatatcctgc ggcgtaaata atcgttatgg tcacccgcac agcgaagtat
    47041 tggagacact agaagaaaat cagataaaaa catggcgaac ggatcaacaa ggaatgatca
    47101 cctatcgctg gcatccagtt tttcatcctc atgggctagt ggaaacaatg atagactagt
    47161 aattctcatc tgctcatggt aggataattt ttgaaagtgg tgagtaattt gagtatacaa
    47221 gcagagttac aaaaaatacg taaagaaaaa cttgcatctt gttacttgat tttaggaaca
    47281 gaaaagtttc tccaagatca agttcggaca gaaattgtca aaaaaatcca attagagggc
    47341 gaagatgact taaatttttt aagttttgac atggaaaatg caagtttaga tgaggtagta
    47401 gctgaagcag agacgttgcc gtttttcgga gatcaacggt tagtattcgt agagaatcct
    47461 tattttttaa caggtgaaaa agtaaacaat ggaatcgaac aaaatactga tttattgacg
    47521 gcttatttga aagaaccatt agaatcgact gtattagtat tctttgcgcc atatgaaaag
    47581 ttggatgaac ggaaaaaagt aacgaaacaa ttgaaaaaaa cagcaattat catcaatgtc
    47641 caacagttga atgaaaaaga agtacgtcaa tatctgatga ataccttaga gaattcctca
    47701 atcaaaatgg aacgaagtgc aattgattta ttcttgaggt tgaccgactt agatttatcc
    47761 aaaatgatga gagagttaca gaaattggtc ctttatggac aaaatcaaca gcaaatcacg
    47821 gtaagagaag tagaagaatt agttcctaaa acgttagaac ataatatttt tgacatgacc
    47881 caatatattt taaaagggaa gacggaacaa gctttgcgtt tatacgaaga tttagttatg
    47941 caaggggaag aaacaatcaa aattaatgcg attttgcttt ctcaattacg tttattttta
    48001 cagacaaaat ttcttgtaaa gattggttat cagcaggcaa atattgctga aacattgaaa
    48061 atccatccat atcgtgtaaa acttgccatg caggaagtaa aaaaattcga tgaacatttg
    48121 ctggtacagt tgtttgatca attagttgag atggattatc aaatcaaaac gggacaaatc
    48181 gaaaaagaat taagttttca actattcgtt ttgcgcacag ggcagttgtt aagaaatcga
    48241 taagaagaaa gacgagggca aagcatgcgg gaaggtcgtt tgtttttgtc ctttttttga
    48301 caaataaaaa aatcggccga agccgattct tttatttagc gatttttttg cttaaacgag
    48361 atttgtcgcg gttagctttg tttttgtgga ttagaccttt tgattcagcc atatcaatag
    48421 ctttaacagc ttctttatat aacgcatcta cgttgtcagc acctgaagct acagcatctt
    48481 caaatttttt gattgcagta cgcatagcgc ttgtttgaga tgaatttttc acattagcgt
    48541 tttcgcttgt acgaacacgt ttgattgcag attcaatgtt tggcattagt ttcacctccg
    48601 ataacttaag ttcttacgcg tgttaccgca taattcaaca ttcattatta tacctaaagg
    48661 cagcgtgctt tgcaatatga acatgacaag tttttttcct taacagtctt ttattaggat
    48721 tttttttcag taaaaacgga tagtacaagc tgaaaaaaat caaaaagacg ctattgtggg
    48781 aggcaatagc gtcaaaccaa actagatttt tatttatcta tttaaacaaa gtttgaatgg
    48841 gaatgtttgg tactaagtta ttatataaca aagagaaccg tttgcaaagt tttttttgaa
    48901 aagggatacg attccctgtt gttctttgtt tttctattaa gaaactgcag ttattttata
    48961 accagtatcc tttgatcagt aaaggctatt ctggtgtacc gattatttta atgtattcat
    49021 cgatattttt tatcaacatt ttttttatga ccaactggtt ccgacggttc catttgccac
    49081 ttacttccag cacatattta tttaggggca aacgtaagat atattttgcc aaatagcgat
    49141 ctttaagcag gccattgatc acacggtcct caagctgcaa gttgatccca gtcagcatca
    49201 ttggctgttc ttgtaaaacg tacgtatcaa ttaaaagacc ttcaaaagtt tccacaagcg
    49261 tcttcctttc ttttcaaagt aacctgaaaa caggcactaa ttcttccatt ttgatattcg
    49321 ttgaagtgga tgcgatcatt ctttcttttg tccactgtaa tctagtataa caaaaaagag
    49381 cagaagagcc aaaaagaaaa aagagcatcg aattctatag gaagtctcat tggcacggcc
    49441 taaattatta caaaacattg attaaaaaaa gcccctgcat cgcaggagca tcccctatat
    49501 cgttttaata ggtcaatcaa aaagcagtat caaacacatt ttgtatcaaa tcaggaaata
    49561 atagataagc taagcccaga atcaaaagta ccgctagaag aaaccagccg attgttccta
    49621 tgaaatactt taatttttcg aacattgtat cacctcgttg tcagtatatc acggatcagt
    49681 aaattggggg tgttaagaat ctcctaaaat agacaaaatt tgttctattt tcctaaagca
    49741 aatacttgta agatacagta agtgatacca gaagcaatga ccggtccggc ggcgattcct
    49801 cttaagaaga caacacctaa aatcgtgccg aaaacaagtg caacagtgat ttgtggatca
    49861 gaagcaatca atcctacacc cttggaagat aagacagcca ctagcccacc gcaaaaaaca
    49921 gctacccagc caatagggga tttaaaggct tctaatagat cacgtagacc gatttctcct
    49981 gttgcgatag ggattagaat agccgctgtg atgatcgtca ccccaatatt gattcctttg
    50041 ccttgaagcc aagggaaaaa ggaacgggag gctggtatga gcttcataat caaaacaaaa
    50101 gctgccgcta tcatcagact ttgattttta gctaaaattg ctacaagtaa aataattcct
    50161 aaaaaaagcc aactttccat gaaatatatt cctcactttc ttcgaaacaa tcataacatg
    50221 tttttagaaa gttacaaaag taggaattca tccttcaaga cctattcata agctgttttt
    50281 ttcataaaat aaacaaaatc ataaaaaaac actttgctta tttgacagaa gacagccgcg
    50341 ctttgtatag tggacaagac ttacattttt ttgaagaatc agaaagatca ggtaaaggtc
    50401 ttagtaaacg caagccattc agaataacca atattgtgct tccttcgtgt cctacaactc
    50461 caagaggtag atttaaaaat tgcaggaagt tagaagcaat caacaagaga ataacaagaa
    50521 tcgaaaaaat aatattttgt ttgatgatcc gccgcatttt taaagatagc cgatgactgt
    50581 agacaaattt atttaagtcg cttttcatta agacgatgtc tgcgatatcc atagcggcat
    50641 ctgtcccttg ccccatagcg acacctaaag aagcggctgc taaagcaggc gcatcattga
    50701 ctccatcacc aaccatcgca tttacttggt aaagttcatt ctcttttttg actagttgtg
    50761 ttttttcttc cggagtacag cttgcatagt aatgttcaat ccctacttgt tcagcaatgg
    50821 cctttgctgt gccagaatgg tcgccggtta tcatacttgt atggatgttt tgggatttaa
    50881 agtaggaaat tacttgttgg gtatttgctt ttggaatatc tagcagacct aaaacagcaa
    50941 ttaactgctg atctttagaa agataaatca cggttttgcc ttgattttcc aaacgttcga
    51001 tcatttccgc aatctctttg ctgattatca tcgtctcagg atcatatgcg tgcttgccaa
    51061 ctttccattg cgcacctaaa taggtagttt gtaatccaaa accagtaatt tcttctattg
    51121 gtaagtattg gatttcttca ggtattgtgc aatcgaaata ttgcaaaatc gcatgagcaa
    51181 gtggatgcgt cgttttttgt tccatagcaa caagaagttg ttgtgccaaa tccttttcat
    51241 caaagaaaaa gctgtcagtt acaactggtt ttcctttagt gagcgttcct gttttatcaa
    51301 aggcaatcgc ttttaattca gaaagctttt ctaaatggat accgcctttg attaaaatcc
    51361 cattttttgc agaatttgaa agagcagcta gagaagctgg tgtagcagat gcgacaagcg
    51421 cacaaggaga agccacaact aataatacca ttcctcgata aaagctttca tcccaactcc
    51481 aacctaggaa aaagtggggg agaaggatca ttagaggaac agcaagcaaa atcaatttta
    51541 cataattatt ttcgattcgt tcgataaatg aagctgtttg agttggcgta ttctgcgctt
    51601 cttctactaa ttggataatc ttagcaaaga cagtttcgga actcgttttt gttactcgaa
    51661 tcgtgatggg atttccttga ttcagcgttc ctgcatacat ctcatcgcct aaatattttt
    51721 ctacaggcac agattcaccg cttaatgcag actcatcgat cgttgcctgt gtgctttcta
    51781 aaaagccatc tatcggaaca gctgctcctt tagcgacaaa taccaagtta tccaccttta
    51841 gttgagaaac atctacttct tgcatttgtc cattttcttt taataattgg gctttttgtg
    51901 gttgaagatt catcaaagca gtaatttctt tttgactttt attagttgtg tattcctcta
    51961 atgcaccgct taaacaaaag atgaatgtca acattgctcc ttcaaagtaa ttaccgatca
    52021 aacaggcacc aatagcagct aaagccatca ataaatccac attcagtgtc cgatcattcc
    52081 acaattcttt caagccttcc gatgtttgtt tatatccacc gatgataatg gcactgatat
    52141 aaaaaagtgg ggtgatggta agagagaatc ggtcgaagat aaaaccgaag atcataaata
    52201 aaaggcagcc gattgttgct gcaaaagctt ttttctgatt agtcatcgtt attagacctc
    52261 cttgtcaaaa caaggatagc ataataaaaa tgtaattgat aataataaca gctaaatgag
    52321 aacgataatg gttatcattt ggtgattaag cttgatgttg tttttattat ttataatgat
    52381 tattattaaa gaaaataaaa aaccagaaca tttctcaaat aagagaagtg ttctggtttt
    52441 ttctacattg caataaacca ataaccaatc aaaatgatac caaggataat acgataccag
    52501 ccaaaagcgg taaagtcgtt tttcttcaaa tagcttagta agaatttgat agctaagacg
    52561 gaaaccacaa aagatacgaa tgttcctaca agaagaacaa cagtttcttc cattttgaat
    52621 gaattccctt cagctaaata tttgacgatc ttcaagccgc ttgcgccaaa catgacagga
    52681 atccctaaga aaaatgaaaa ctctgtagcg acaaaacgcg aagcaccaat caagatagat
    52741 cctaggatcg ttgcgccaga acgggatgtt ccgggaacaa gtgccaagac ttggaataac
    52801 ccaacaagaa gagctgcttg gtacgtaaag tcattcagag aagtccaacg aggtgttttg
    52861 tttttgttgc gtttttcgac aataataaag gcaataccgt aaacgatcaa aacaatggca
    52921 actggtaaga acttgtggaa atttgcttct aaccaatcat ccaaaggcaa accaatgatg
    52981 atggctggta tgcaagcaac gatcacttta aaccaaagtg tccacgtatc ttttttttct
    53041 accgttgatt tacttggaga aaatgggttt aacttgtgaa aataaagaac gacgacagcc
    53101 aagatcgccc ctaattggat aacgacattg aacatcgaca taaattgtga actggcatcc
    53161 agtttgatga attcatctgc taggatcaaa tgaccagtac tactgatggg cagccattcc
    53221 gttattcctt caataatacc gagaatcact gctttgataa tatttgcaaa aaacataaat
    53281 tccttccttc ccaattaaga tacatcttat agtataccgt tattttttga gaaacccaat
    53341 ctgtttttta atattaagaa aaacttgaga aataaagcag ataagtacac gaagagaaaa
    53401 aagaagacaa agccctcgtt cagactttgc cttttatgat tctctggtaa aaattaaaat
    53461 atccccatta tagaaacgag tcgcgactat gtgttttccc gttatcgata taagacgtat
    53521 cattgatgcc gtggatagaa aatcgaccgt ttgcataagt gacctttgtt acgctgccat
    53581 ttaaaagccc agcacgaaca ggctgtttag gatcgatcag attaagcaaa aaggcgatcg
    53641 tcaaaccatg agatacgact aaaacatttc caccaccatt tttttcgcag tgatgggcga
    53701 tatcttcaaa tcctgtccat acacggtctc gcaatgtttc ataagtttcc gcccacccag
    53761 cggtatctaa gttgtataca gcattagcaa tttgttcaaa agaaacttct gtggtaaaca
    53821 tttcatcata tgttttaaaa ttcaatacac gagggatcac accccacatt tccatgtcat
    53881 atccaccttc aagagacccg aaacaccatt ctctaatcct tttttcaata aaataaggaa
    53941 tttcttttcc cttagaatgt tctcctagaa taatacgggc agtttcgatt gcacgaccac
    54001 tgtcactaga ataagcaaat gaaaagtcga cattttttaa cccgcgacct aaataatgaa
    54061 tgccttcttg tccttgcttt gtgaggggtg tatcacacca gccttgtact cgttcaattg
    54121 tattgaacat cgtttttccg tgtcgtacga tataaagtgt agtttctgtc attttattct
    54181 cctcctaagt cgttttaacg attgaaaaaa ggatttgtcc ttttttcctg ttcaatcgtc
    54241 gttgcatcgc catgtcctgg atagactgca aattcatcag gtaatacaaa cagctgggtc
    54301 cgaatactat gaagtaattg ttctaaattc cctgtataca gatcggttct accgatactt
    54361 cctctaaaca gggcgtcgcc agaaacgaca aaatcatcaa aaataaagct gacgcttcct
    54421 atagaatgcc ctggggtagg gacgacgcga aaagacatgt ttcctaaagt ataagttttc
    54481 atttcaaatt catattctgc aggcgagaca ataacatcag caatatcatc atgtctaccg
    54541 agtccagaaa gattcaaaat cggatcacct agccattttt gctctagtgg gctgacataa
    54601 actgggattt gataatacgc gcgtaaaggt tccactgcac cgatatgatc gtagtgagta
    54661 tgggtaagca aaatcgctac cggctgttgg tttgtttttt tgatttcttg tttgattcgt
    54721 tccgcatctt ctccagggtc aatgatcaaa agtgcttctt cgttgtagac caaataacag
    54781 ttttcttcaa tcattcctgt ttttaatctt tcgatatgca tgtgcattcc tccttgatag
    54841 ccaaaacttc tttcatccat tagtataacg cattcattgc taggaaacaa aaacaggtac
    54901 ttatttctct ttacttatct gaattatcag actatatgaa aagtatttgg atattctaaa
    54961 gagaaggaaa gtaagttttc atagcatttt aatatgtcct tgttacatta gattcatcca
    55021 aaaatccaaa ttctatatcc tatatccctg cctaatcagc agggtgtttt tttatgtttg
    55081 gaaagagagc tctttttgct aaactaggtt ttttcaggta atcttagaga gaaagaggtg
    55141 gtggaaatga tcaaacagtc aaaaatatct gtgcggcact tagtagaatt tattttgcga
    55201 cgtggaagta tcgacaatcg taaaaaaagt aaccatactg cattagaagg agcgagaatc
    55261 caccgcaagc tccaaaaaga tgcgggagaa aactatgaaa aagaagtctt tttaaaaaca
    55321 acagttcaat tagatgaata ttacctgatc gttgaaggcc gtgcagacgg tattttcaaa
    55381 agagacggta tttattatat agatgaaatc aaaacctccg aaccacgatt tgaagattta
    55441 gaaccagaac aagtggaact tttctttcat caagcaaggg tgtatgccta tatctatagt
    55501 caagaacatg atttacaaga aataaatctg caattgactt acttccagac ggcagaagaa
    55561 gtgatcacga gaaaggttga acatcagaca agagagcagt tagaaacttt ttttaaaaag
    55621 ctgactgaag attataaaga atggcttgtt tttcaagaaa actggcgcac tgtacgcaat
    55681 gcctctttga tggctttgaa attcccccat gatgagtata ggaaaggtca gcgtgaacta
    55741 gcggtagctg cttataaaac gatccgtacg aaacagaaat tgtttgtaga agcacctacc
    55801 ggaacaggaa aaacaatctc tacgttattc cccgctttga aagctgtagg ggaagaagag
    55861 ggagaaaaga tcttttatct aacggctaaa acaataacta gacaagtagc tgaagatgct
    55921 atgacagcat taaaagatac aggagctgaa gtaaaaagtg tcactttgac ggcgaaagac
    55981 aagatctgct ttttagatga gacgacctgt aatccagatc agtgcccata tgccaatggt
    56041 tattacaatc ggattaatga aggtttatgg gatcttttga atcatgagaa tcagatcact
    56101 cgtgaagtca tcgaaactta tgcaagaaag catacacttt gtcctttcga actatcatta
    56161 gatgtcagta tctggtgtga cgtaatcatt ggggattaca attatttatt tgatccaact
    56221 gtttatttaa gacgtttttt tgaagatgaa aaaaacgagg actatctgtt tttgattgac
    56281 gaagcacata atttggtgaa tcgttcccga gagatgtatt cggcagaact atcttatgaa
    56341 aaaacgaaac gaagtaagga agctatacca aaggaattca aaaaacttca tcgccgtttc
    56401 aacaaactat taaaagaatt tgattcgatc cgagaaatag caaaagaaga tcattgggat
    56461 tatcatcatc aaaaagcacc ggctgaatct ttagtaaagg caggttatca attaagcgaa
    56521 aaaattaaag aatggctggc agaatttcct gagcacccat cacaagaaca attgcttcct
    56581 tattattttg atttgcttca ttttttgaag gtcagtgaat tttatgatga tcactacgaa
    56641 acaacagtcg aaaaaacgta tcgcgatctg atagtaaaag agttttgtat tgatccaagc
    56701 ttgtttcttg agcagtcgtt ggataaagga aaaagcagta ttcttttttc tgctagtttt
    56761 tcaccactct cttattatca ggaaacactg gggggacaaa aaagtctggc ttacaaactg
    56821 ccgagtcctt tcccagaagg aaaccagcaa gttttcatcg caaattacct agagacgact
    56881 tatcgaaaaa gggaacacag tctggcaaaa ttagtagaga cgattcatgc ttttgctgat
    56941 ggaaaggtcg ggaattattt cgttttcttt ccttcttatc aatatttaga tcttgcggtg
    57001 gaagcattca gacagcaata tcccgacagc aatgtgctaa tccaagaaac ggacatgaat
    57061 gaggaagaac gcgaacgatt tttaacaaaa tttcaaacaa atcccgctga aacattgatt
    57121 ggattttgcg tacttggcgg gattttttca gaaggaatcg atttgagagg ggaccgattg
    57181 atcggcagta tgatcgtagg tgtaggtttg ccgcagatga atcatgagca ggaactgatc
    57241 aaatcatatt atgatgagaa ggaacacctt ggatttgctt acgcttatca gcttcctgga
    57301 atgaacaaag tcttgcaagc tggtggtcga gtgattcgtg gcatggcgga tcaaggaatc
    57361 gttgtattgg cagatcaacg attttctagt ttttcttatc gacgtttatt cccacaacat
    57421 tggcaaacag caagagaagt acgaagtgtt ggggaattgg aagaaggaat acagcgtttt
    57481 tggttatcaa aagaagcagt aaatcaaaaa aacgaggaat gacagacgtc agcctcgttt
    57541 tttgattaac gatagttagt gaattgcaac tcgattggta agtcaagttt acgtaataaa
    57601 gcaatcacag cttgtagatc atcacggttc ttacctgtca ctctaatctg atcttcttgg
    57661 atttgtgctt ttactttcag tttttcattt ttgatagctg tagtgatttt cttcgcgttt
    57721 tcacgatcga ttccgttgac caaatcggca gtttgtcgag ctttgccacc tagagcgtgt
    57781 tctgattcgg aaaaatggat atttttgatt ggcacatttc ttttgatcag cttaccaaat
    57841 aatacatctt tgatctgttc gattttgaaa tcatcatcgc tcaatacaac tagattgctg
    57901 ttctctaatt tgatttctac tgtagaatcc ttgaagtcaa agcgattgga caattctttt
    57961 gttgtttgct gaatcgcatt ttttacttct tctgtattga cttctgatac aatgtcgaag
    58021 ctagcatctt ttgccatagg aaccctcctg atatacatat aaatatttac catacatcta
    58081 tcttatcata ggattagggc agattcttac ctgtttgcta aaattcttct catttgagtt
    58141 cgaagtattt tattttaata gataaactgt tattcttaca tttggaatac caaagtaggg
    58201 gagaggtgct tgtgagtaaa attatgactg cgtatcataa aaatgaaaga ttaaagaaaa
    58261 tagtggttat tttgataacc ggattgaccg ctgcggtcgc tttaaattat tttttgattc
    58321 cagccaatgt cttttctgca gggatgaatg ggatcgctca aatcatttcc tcgcttttat
    58381 atgaatggtt tcatatcaag atagacacag gaacatttat ttttcttttg aatatccctg
    58441 tgtttgtatt agggtttctc aaagtaggaa aacgagcaac gatccttagt tttgtgaatg
    58501 ttgtatgtgt atcggtgatg acgatgctgc ttccagtcgg acagatcact gataatattt
    58561 tgatgaatgc cctagtaggc ggtgttttat taggtcttgg cgtaggatta tctttaaaaa
    58621 tgggctttac aactggtggg atggatatca tctctcttgt actttcacaa acaactggaa
    58681 aaacagtcgg aaactacatg ctgattctaa atggtatcat tgtagtcatc gcaggcttct
    58741 tctttaactg ggaaagtgcc ttgtatacga ttatttccat ttatgcaatg actcaagtaa
    58801 ttgatgccat ccacacgagt catcaaaaag taacagcaat gatcgttacc gtcaagccag
    58861 aagaggtaac agaagaacta gcaaaacgga tggtacgtgg aatgacatta ctgccgtctg
    58921 tcggtggcta ttcaaaaaaa caagggaaca tgatcatgat ggtcatcacc cgctacgaaa
    58981 tgtatgatct tgatcagatc gttcatgaaa tcgacgacga tgcatttatc aatattttac
    59041 caactcattc agtatttggc cggtttgcaa atgaaaacga acaaaaaatg tatcgaacaa
    59101 ctggcgtatt gccagaaata aaaaatcgtt cacaaaaaaa atgaggaatc aggtttattt
    59161 tagaataaat ttaatctatt acatctaata agaacatttt tataaattta aacgagaatc
    59221 ttacttctaa attctcattt acaagcagct aaaaaaagag tatgataaat aaaaatcgtg
    59281 ttaaggagtg tcgtacgatg agcgaagcaa accaagaacg gtctggacaa gaaatagaac
    59341 taatcaaaga acgtattctt gctgccttgg aaatggtgat tgatcctgaa ttaggaatcg
    59401 acatcgtcaa tttaggcttg atttatgata tagaattcaa tcctgaaaat ggagaaacag
    59461 tcattaagat gactctaaca actatgggct gtccattagc agatatttta acagaatcta
    59521 tccatgacgc attaaaagaa gtgccagaag taacgaaagc agaagtcaaa ctagtctggt
    59581 atccagcatg gacgacagat aagatgagcc gttatgcacg gattgcgttg gggatacgat
    59641 agaaatcttg gctgactagc tatgagaagc aaataggaaa aacaaaaaag ccttttatcc
    59701 tttctagaag aaaagagata aaaggtttct ttgtttataa aattttgtct gctatattat
    59761 aagttaatta aataaatgtg ttctattgat aaaggacatt caaatccctt tccttttgga
    59821 atccttcttt tttacatcag tttgattttc gtatagtatt ctttctcatc ttcacgataa
    59881 atcgcagccc catttttttg ttgtgcttta agactgccaa gatttttttt atttacagac
    59941 aaaagtgcct catcaatgcc gatttttttt gcctcttgta gtactaatgc taatccttgt
    60001 gtggcatatc cttttttacg ataattaggg gagatgccgt aaccaatatg gccagcgccg
    60061 tttcttaatg tttcgttcag tttatggcgc aaattaaaaa ttcctacata ctcatgttca
    60121 tcactttcta aaataaagac ggttgcggga acgtaactct caggaagatc gattcctaaa
    60181 gacgtttttt cgcatttttt tacataatct aaaaattcag caaatgtata gccataagca
    60241 ttgttgataa atccactctc atttggtcca aagctagttt gtagctgata agctttcttt
    60301 aaatctgctt cccatagttt gatcagtttc atcgtattca cctctttaag taaccttatt
    60361 catttgtttt ctactatagc actattgttg taaatagcca tgcctatttt tatttattgt
    60421 gtcatatcgt attaagaatc atcgaacaat acaaatatga attacaataa aaaaattatt
    60481 tgaagttcgt tcattcgtta cttatgatct ctagaagaaa gaaaacgtga attacttcag
    60541 cgtctagaat tccagaagga tagtaatcaa cagaagaaat aatcaatatc caaatgaaag
    60601 aagatagctg aatcgagaaa aagaggaaaa aagaaatgaa gaaaaaaata aaatagttac
    60661 taatcccaga gtcgttcgtt taacattgaa atcgatcata tggataaaac agattttttc
    60721 accaaccctc aatagatgat ggagttgctc ggatgaatta tttgtgtaga tggcataagg
    60781 gagggcgtac agaaatgaaa aagaacaaaa atatgttctt gacaaaaaac acatgtaatc
    60841 ctaaactaaa agatgtgatg cggctatggc ggaattggca gacgcgctag cttcaggcgc
    60901 tagtgagggt gacctcgtgg aagttcgagt cttcttagcc gcataatttg tttttttata
    60961 aagagaaggt acacctggag cgatgagaaa gaaaataaca tattatctaa aagaatatag
    61021 gaaaaatttt aaacaacgga accagattca aataaatcaa aaaaaatttg tgtgaaggtg
    61081 ggacagttta aaacctaata gattgattca aatagtagat ttatagattc tgatacaaga
    61141 aatactggca aacgatagtt aaggaataaa gactaaactt aaactcaaaa agaggtcatg
    61201 cgaaagaata aatcgcatga cctcttacta tattttgaat gtgtttaaac gttcaaataa
    61261 tgaatcttag taccaaccgt ttgcttccca gaatgctttc gccgcttccc aagaaccata
    61321 acgtgaagta acatattgtt ctgctactct ttcttggttt gcagcagagt agtcaccatt
    61381 taagtaagaa gaatctaatt ggtaacggcc gatgtaacgt ccgttcgttg ctgtgtaaga
    61441 accgcttgat tctttttgtg cgatccattc ttttgcagag cttgtacttg ctggagtagc
    61501 agcagtttct gttacagcag gagcaggttg tgtttcagca acaggcgctg cttgtgtttc
    61561 cgtttgaacc gtttcttgta caacaggttg ttcagcttga acaggttcag cttggactgg
    61621 tgcttcttga acggctgctt gaggttcagc agctgcttgt gcagagcctt ctgttgggat
    61681 tgttaattgt tgtcctgagt a
//
LOCUS       DADGKS010000011        57537 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.011, whole genome shotgun sequence.
ACCESSION   DADGKS010000011 DADGKS010000000
VERSION     DADGKS010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 57537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57537
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.011"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            212..604
                     /locus_tag="JXV47_000728"
     CDS             212..604
                     /locus_tag="JXV47_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAX1486789.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="JXV47_000729"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="JXV47_000729"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HAX1486790.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="JXV47_000730"
     CDS             3165..4775
                     /locus_tag="JXV47_000730"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HAX1486791.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="JXV47_000731"
     CDS             5067..5936
                     /locus_tag="JXV47_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HAX1486792.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="JXV47_000732"
     CDS             6101..7372
                     /locus_tag="JXV47_000732"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAX1486793.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /locus_tag="JXV47_000733"
     CDS             7369..8664
                     /locus_tag="JXV47_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HAX1486794.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="JXV47_000734"
     CDS             8763..9026
                     /locus_tag="JXV47_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HAX1486795.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="JXV47_000735"
     CDS             9471..9920
                     /locus_tag="JXV47_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAX1486796.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="JXV47_000736"
     CDS             9977..11395
                     /locus_tag="JXV47_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1486797.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="JXV47_000737"
     CDS             11395..12255
                     /locus_tag="JXV47_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HAX1486798.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="JXV47_000738"
     CDS             12429..13202
                     /locus_tag="JXV47_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAX1486799.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="JXV47_000739"
     CDS             13349..13714
                     /locus_tag="JXV47_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HAX1486800.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="JXV47_000740"
     CDS             complement(13862..15070)
                     /locus_tag="JXV47_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAX1486801.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="JXV47_000741"
     CDS             complement(15089..15367)
                     /locus_tag="JXV47_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486802.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15560..16216
                     /locus_tag="JXV47_000742"
     CDS             15560..16216
                     /locus_tag="JXV47_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAX1486803.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            complement(16658..17455)
                     /locus_tag="JXV47_000743"
     CDS             complement(16658..17455)
                     /locus_tag="JXV47_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HAX1486804.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="JXV47_000744"
     CDS             complement(17452..18636)
                     /locus_tag="JXV47_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAX1486805.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="JXV47_000745"
     CDS             complement(18661..19908)
                     /locus_tag="JXV47_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virion core protein"
                     /protein_id="HAX1486806.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="JXV47_000746"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="JXV47_000746"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HAX1486807.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="JXV47_000747"
     CDS             21888..22202
                     /locus_tag="JXV47_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HAX1486808.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="JXV47_000748"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="JXV47_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HAX1486809.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="JXV47_000749"
     CDS             22887..23531
                     /locus_tag="JXV47_000749"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HAX1486810.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="JXV47_000750"
     CDS             23546..23875
                     /locus_tag="JXV47_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486811.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="JXV47_000751"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="JXV47_000751"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HAX1486812.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="JXV47_000752"
     CDS             24863..25687
                     /locus_tag="JXV47_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HAX1486813.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="JXV47_000753"
     CDS             25680..26027
                     /locus_tag="JXV47_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HAX1486814.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="JXV47_000754"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="JXV47_000754"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HAX1486815.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="JXV47_000755"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="JXV47_000755"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HAX1486816.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="JXV47_000756"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="JXV47_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HAX1486817.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="JXV47_000757"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="JXV47_000757"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HAX1486818.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31684..32451
                     /locus_tag="JXV47_000758"
     CDS             31684..32451
                     /locus_tag="JXV47_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1486819.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="JXV47_000759"
     CDS             32441..34483
                     /locus_tag="JXV47_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1486820.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="JXV47_000760"
     CDS             34764..34913
                     /locus_tag="JXV47_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HAX1486821.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="JXV47_000761"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="JXV47_000761"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HAX1486822.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="JXV47_000762"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="JXV47_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HAX1486823.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="JXV47_000763"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="JXV47_000763"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HAX1486824.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            37921..39189
                     /gene="dltD"
                     /locus_tag="JXV47_000764"
     CDS             37921..39189
                     /gene="dltD"
                     /locus_tag="JXV47_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HAX1486825.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39330..40412
                     /locus_tag="JXV47_000765"
     CDS             39330..40412
                     /locus_tag="JXV47_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HAX1486826.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40412..41215
                     /locus_tag="JXV47_000766"
     CDS             40412..41215
                     /locus_tag="JXV47_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAX1486827.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41285..42025
                     /locus_tag="JXV47_000767"
     CDS             41285..42025
                     /locus_tag="JXV47_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAX1486828.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42036..43040
                     /locus_tag="JXV47_000768"
     CDS             42036..43040
                     /locus_tag="JXV47_000768"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HAX1486829.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43085..44929)
                     /locus_tag="JXV47_000769"
     CDS             complement(43085..44929)
                     /locus_tag="JXV47_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486830.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
     gene            45140..45658
                     /locus_tag="JXV47_000770"
     CDS             45140..45658
                     /locus_tag="JXV47_000770"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAX1486831.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            45786..46469
                     /locus_tag="JXV47_000771"
     CDS             45786..46469
                     /locus_tag="JXV47_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HAX1486832.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            46778..46851
                     /locus_tag="JXV47_000772"
     tRNA            46778..46851
                     /locus_tag="JXV47_000772"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:46812..46814,aa:Arg,seq:tct)
     gene            47010..47369
                     /locus_tag="JXV47_000773"
     CDS             47010..47369
                     /locus_tag="JXV47_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HAX1486833.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            47492..49123
                     /locus_tag="JXV47_000774"
     CDS             47492..49123
                     /locus_tag="JXV47_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HAX1486834.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(49185..49826)
                     /locus_tag="JXV47_000775"
     CDS             complement(49185..49826)
                     /locus_tag="JXV47_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAX1486835.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     gene            50108..50416
                     /gene="rplU"
                     /locus_tag="JXV47_000776"
     CDS             50108..50416
                     /gene="rplU"
                     /locus_tag="JXV47_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HAX1486836.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            50443..50787
                     /locus_tag="JXV47_000777"
     CDS             50443..50787
                     /locus_tag="JXV47_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HAX1486837.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            50800..51093
                     /gene="rpmA"
                     /locus_tag="JXV47_000778"
     CDS             50800..51093
                     /gene="rpmA"
                     /locus_tag="JXV47_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HAX1486838.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            51500..54334
                     /locus_tag="JXV47_000779"
     CDS             51500..54334
                     /locus_tag="JXV47_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAX1486839.1"
                     /translation="MAKRIDRIYMYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNS
                     SKDLNQLVREGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDT
                     KDIFAKIIGANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAH
                     HVIDEETELIVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLD
                     EIHRLPPEGQEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRI
                     PINIKLPAFEKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQL
                     KSNIQLVCARGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKIT
                     VAPNDTIMKIQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFY
                     KDHGFSFNADSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKK
                     INLGEERHTNDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLR
                     ANQASGRIGVVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNV
                     QEVDEGSGVILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDL
                     DMLHESLKNFRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNK
                     RQETELEVLALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVI
                     LDQLLMESELEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTT
                     GIGDEEYGFKINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLED
                     QIKVKVPIEEMYYLLRLVHNQLDKKEYTVP"
     gene            54525..55016
                     /locus_tag="JXV47_000780"
     CDS             54525..55016
                     /locus_tag="JXV47_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIB"
                     /protein_id="HAX1486840.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            55119..56108
                     /gene="manX"
                     /locus_tag="JXV47_000781"
     CDS             55119..56108
                     /gene="manX"
                     /locus_tag="JXV47_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HAX1486841.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            56141..56944
                     /locus_tag="JXV47_000782"
     CDS             56141..56944
                     /locus_tag="JXV47_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HAX1486842.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            56965..>57537
                     /locus_tag="JXV47_000783"
     CDS             56965..>57537
                     /locus_tag="JXV47_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HAX1486843.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGM"
BASE COUNT        18484 a         9934 c        12076 g        17043 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtag ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcgaaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg tgcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    39241 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    39301 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    39361 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    39421 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    39481 aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt
    39541 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    39601 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    39661 acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt
    39721 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    39781 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    39841 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    39901 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    39961 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    40021 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    40081 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    40141 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    40201 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    40261 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    40321 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    40381 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    40441 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    40501 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    40561 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    40621 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    40681 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    40741 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    40801 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    40861 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    40921 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    40981 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    41041 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    41101 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    41161 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    41221 aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg
    41281 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    41341 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    41401 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    41461 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    41521 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    41581 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    41641 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    41701 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    41761 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    41821 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    41881 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    41941 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    42001 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    42061 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    42121 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    42181 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    42241 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    42301 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    42361 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    42421 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    42481 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    42541 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    42601 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    42661 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    42721 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    42781 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    42841 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    42901 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    42961 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    43021 tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta
    43081 ttttttatac aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag
    43141 tatctttttc ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc atcatcatta
    43201 agtcaaaacg ttcctgatca tctaattctt ctgtgatgcc tcgactaaat aggtttgtat
    43261 cgtaatgtgc actatgttcg caacaaatga cgaaatgttc ctcttgttcg tgtatcgaca
    43321 aataaatttt tcgatacagt ggattttcga tggcatgagt ttctctaaag gaatgctcta
    43381 aagcgtggat caaaagttga gccagatcgt catcgttgat aggaagttct tcgggaagat
    43441 ctgcttggaa ggttatctga atattccgtt tggcagctaa cttctggtaa cgcgctaaga
    43501 taagatttgt cacctggtgg ttgcaaaaag aacacagcat ttcgaaattt tttgcttctt
    43561 ctaatatctt ttccacatag tttttagctt ttgtttggtc cgtatgcatt aaatcttgca
    43621 gattctccat ctcttggaca aattccaggc gaagtgtatt tacttcttgg atatgctgtc
    43681 gaagctgctc ataatgttgc tccaacaaat catttttgat ttttaagaaa tctacttgtc
    43741 tccgatcttt gtcggtattt aagatgtgat cgattagatt gtagctgata ataacgatta
    43801 gaatgataat atataaaatc gtagaccaat tgatcgttgt ttgatagata cctaatgccg
    43861 tttggatgta aatcaagcaa tggataatgg ctaccaagac gatccaaggt gtacaagcta
    43921 cataaaaacg gttattctta tatgcttcgc caatgcatgc aagtgaagtg actaaagtgc
    43981 ttataacact agcaatatta gcaatcggca ttaattcagg aagttctgca ggagtaaaag
    44041 ttgcataaag cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa attccgtacc
    44101 attttttata gtaaaacatt cggctccaat agtagcagat gatgaaagct gacgttaaga
    44161 taataaataa atgagataaa aaagaatgaa cgaatggttc aaaaagaata ccacttaaaa
    44221 tatcttctga tacagcttca aatcctaatg ccaaagcaaa gcaacttaag agaataagtg
    44281 agtattcaag acgtttttgt ttatacatca agtagatcgt atagaaaaag gtccctatag
    44341 cgataaaaac agcgattatc atcgtcaata cttgcggcac tgattgtgaa taaataaaac
    44401 taatcaatgg tccagttgtt cctagataaa ctttcggtgg cagtccagca tagttctgat
    44461 aaggagatga gactgtaagg gtcaattttt ttccgatata atttgctggt aaatctatca
    44521 cagccaatga gagtccggga ttgctttctt cctgataatc tttccgttgg tataaaatct
    44581 tttcgcctag atatacagta atccattgat ggtttccttt gattagtaaa tttgcttcgt
    44641 ccaacggttt ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc acggtaggaa
    44701 tcgtacgagt gtacttgctg tcaaacttaa aatcaggatc atcttttgta tagaaaaccc
    44761 acgaatcttt tatttctttc atttgattgc tgtccgcagg agaaaaaata aaataaaaga
    44821 aataagcaat tcctgttaaa aataacaatg ataatataat gattatgctc cactttatac
    44881 gtaaataaaa agattctttt ttattatata tgttattaaa aaaagacata aaggtattcc
    44941 tttctaaaac ttgtaatgtt agggtaaacg ttttttaaac taacgtcaat tatttataat
    45001 aaaaaatgag ataaagatga ggaaatagaa ttagaaacat ataattatta aagggaaaca
    45061 tttttacagc tataatttga aaaaatttat cgttattata tgattaagaa ggattgaata
    45121 aagaaagaag ttgaaaacga tacctgatta caaaaaaata acttttataa gttctataac
    45181 gttgattata tttttaattc ttattcttct cgtcgtcttg gttccccgaa tttttggttt
    45241 gactccttat attattgagg acaaagaaat gagtccatat tatgcacaag gaaatctgat
    45301 atatgtacga ccgaaaaata caaatgagat tttagtcgga gatattatta catattatga
    45361 aaattcagga aaaaaaatct cgacgcgtcg cgtaatagcc gttgaaaaca accacgaaga
    45421 tttttataca aaagctgata caaagactta tattgagcct ggagtagtaa aaaagagaaa
    45481 tattatcggt agtcccatct ttcagattcc atatattgga ctagtccttt caaaaacggc
    45541 atttgcatgg attcaggggt tattctttac gattgctttt tgcctaacag gaatcacagc
    45601 atggaatacc tttgtagagt tgaaaaagaa gcggagacga acacagaaat ttttgtaaga
    45661 atgttaaaaa cataaatgta ttccagagat ccaacgactc ttctgaacat gaaacacgag
    45721 aaaacactca tgcagcttgt agatttagtc agttgttcgt ataatgtgtg aagaggagga
    45781 gtagtatgcg caatgaaatg atgcatcgtc ctgtagtcaa agaagaacta ttggatttta
    45841 tgcgtaccca gcaaaaaaaa ttaccgggtg agctaggcaa actggaagaa gaagctcatg
    45901 tagcagaagt accagttatt ccccatgaaa cagttgtatt tttgaaattt ttacttggac
    45961 agcttcagcc tgaacgaatc ttggagatcg gagcagctat cggtttttca tcaagtgtca
    46021 tggccacgac aatcggagaa aacgctcatg ttacgacaat tgatcgtttc gatgtcatga
    46081 tcgagaaagc taaaaaaaac tatgaacgtc taggactgac agataaagtg actttgcttg
    46141 aaggtcaagc agcagatatc ttgccggagt tgtctggtcc gtatgacttt atttttatgg
    46201 atagtgcaaa atcaaaatat attgaatttt tacctgaatg cttacgtttg ttaagaaaag
    46261 gtggcgtttt gatggtagat gacatcttcc aaggaggaac gatcttgctc ccagatgaag
    46321 agattccccg tggcaaacga gctatccatc gtaaattaaa tgaatttctt cgtgttgtga
    46381 tggatcatcc cgatttgaca tcgacaatct tgccattagg tgatggtgtg atcttaatga
    46441 caaaggaatc agaaacaatc gagttgtgat acatgattat ggcagcctgt agataatcga
    46501 ttgaatcgag ggctcaattc gaacttgatg taaaagtttc tatatttgta agtcaattaa
    46561 aggatacagg aaatctaaat aaacaggagt agcatgaagt caatgtagct cctgttttca
    46621 attgataacc ttagaacagc tgaaggagaa tgtctcgttt taaaagattg atttagtagt
    46681 tgggccaaaa taattcatta tttgctaatt aaataactat ttcgtattga cagaagcaat
    46741 ttaattatct ataattattg atgttccgct gattcttgtc atagtagctc agctggatag
    46801 agcatccgcc ttctaagcgg acggtcgggg gttcgaatcc ctcctgtgac gctaaaaaac
    46861 cgttagaaac tgaggtttct aacggttttt ctttgttttt tgtgccaata ttgtttgttt
    46921 tcaaaggcaa ataaaataaa aaaacatcct tatcgagtac aattataagg agcaaaaaaa
    46981 taaaactcat cagaaaagag gaagaagata tgacgatact atctagaatt ttagtgactc
    47041 tagttgcaat tgaatttttt tatatcatgt atatcgaaac ggtgagaact gattctgaca
    47101 cgacaagtag ggtttttaaa atgagtaaag aagagttaag cagaaaatct gttcaaacat
    47161 tgtttaagaa ccaaggagtg tacaatggac tattaggagt gggactactt tatggagctt
    47221 atctttcttc cgcatctaaa gaaatcacaa gtatgctatt aatatctatt ttttttgttg
    47281 cattatatgg cagtttgact agcgatcgtt ggattttact caaacaaggt gggctagctc
    47341 tgttggcatt gctttctatt ttcttataaa tatagaaaaa ataagaattt atctaacagg
    47401 aaactttgtg aaaaatatta ctttatctca tgaaatatga tattctaatg aatggtattt
    47461 tagaaaattt catgaaaaag gagttagata ggtgttcaaa aattatgttt cctcactaaa
    47521 aaaagaattt tcaggttatg atctttcaag atttcagaaa gatcttttgg ctgggatcac
    47581 agtagctgct gtagcattgc ctttagcctt ggcttttggg gtatcaagcg gagctgatgc
    47641 ggccgcaggt ttgattacgg ctatcattgc cggtatcgtt attggcggtt tatcaggcgg
    47701 tttttatcaa atatcaggtc cgacaggtgc gatggcagct atcttgatgt ctattgcggc
    47761 aacaaaggga atgcaaggtg tattgcttgc tactttttta gcgggtctat ttttacttgc
    47821 agcaggactt ttccgattag gaacactgac ttcttttatc ccagcacccg taattacggg
    47881 gtttacttca ggtattgcta tcattattgc attaggtcag atcgataatt tatttggtgt
    47941 tcactcggaa ggtacaaacg ttattgaaaa actaagtagt tatcaaacga taggatttcc
    48001 gataaacaca gcctctttga tcatgggagg gctagtcatt ttagggatgt ttatctatcc
    48061 aaaaaaatgg gcgaaacgaa tgcctagttc gctgctggct atcattttgg caacagcagt
    48121 tatgctattg ttccatttac cagtagcaac tgtgggtaag attccacaaa cattgatcag
    48181 tagtaatcgt ttgaatatgg gagattttag cttttctgcc ttgcaacaag tggcagttcc
    48241 agctattagc attgctttat taggaatgat tgaaagcttg ctatgtggtg cttcggctgg
    48301 ccgaatggca aataagccct tagatagcaa tcaagaatta atggcgcaag gaattggaaa
    48361 tctgttgctt cctttctttg gcgggattcc tgctactgcg gccatcgccc gtacaagcgt
    48421 ggccatcaaa tctggtgcac aaactagatt agctggtatg atacatgcag ttgtcttact
    48481 gctctccatg cttgtttttg cgccagtgat gtcacagatt ccaatgccag cacttgcagg
    48541 tgttttgatt gtgacggctt ggcgtatgaa tgaatgggaa acgatcaagg agctatttac
    48601 taataaatat tggtcagcag ttctattgtt tatccttacg atgatttgta cagttatctt
    48661 tgatttaagt attgctatcg tgatcggggt gatcggcggc tgtgtatttt ttgttgtcaa
    48721 aagcgctgct atcacgattt cattagaaac gatcgattgg caaagaatgg ggctgccaga
    48781 aacggaaaag ctgaataact ggacagtagt gtatattagt ggtccactgt tttttatgtc
    48841 ttcagaaaaa ctcaaaaata aattggaaga actaaatcat cacgatggtg tcattttctc
    48901 catgcgaggc gtaccaagta ttgatttgac ggcacgtgca gtttttgatg aatttcaaga
    48961 aaaagcagag caaagaggac aaacgattat ctatacttcc ttgcagccag aagtagaaaa
    49021 acaactttct cacttgtggg aacatacatt cacgcatcaa catcaaacag ttgctcatgc
    49081 gttgacagct ttacatgcga aatatactgc aattagccat taaaacaatg aaaaagaaca
    49141 gacaagactg taaactgaag attttatggt cttgtctgtt ctttttaata ttgctgtaaa
    49201 agtgaagcta gtacttgcca gtcttgatgg ataacaggta caagggagcg attgtagaaa
    49261 atagctgctg gatgaaaaag tggaagaatt cgatagtttt tttctgacca ttcgtaggca
    49321 tccttttgtt ctgttaattg taagacaggc cctgtataga gttgaccatg atttttggta
    49381 accgtatatt ctttgccaag taaacgttga agaccaatgt ttccaagtgt cgcaattaat
    49441 tttggctgga ccttcatcag ttcgtaatcc aatattggtg catgcgcaaa tacttcggaa
    49501 cgagtaggtg tccgatttgg ataaacagtt tctgactgtt gtgtccgttt attgatccga
    49561 tgagtcacgc gatacgggcg gctccttaca gcactggtga tatacacctc ttctcgtgtt
    49621 aagccagttg aagaaagtgc ctgcatcaat tcttttccag cttgaccgct aaaaggaaca
    49681 tgcgtatcaa tctctgtttt ccctggggct tctcccacga gcatcagttt aggatgaaga
    49741 ggtccttgcc cagcgataaa tccttctaca ggacggccgt tcattcttaa agaagcttct
    49801 tgtatcagtt cttttgggta ttccatttat gctcctcctt tttcttttat tataagaata
    49861 aaagaaacac aatgcgacta ttttatttgg tagaactgtg aggatagaaa agcagaagta
    49921 ttgcttgaat ttttgtttta ctttttgatt ttaaatttag ttgactaacg gttgctgttc
    49981 tggtaagcta gtactgttgt aattgtggac tccacagcta caaccgctca gaacaagtaa
    50041 taagcacagc atatgctgtc acttcggatg gcgagtctaa gtatatcaga aggaggtgct
    50101 ttatagcatg tacgcaatta ttaaaactgg tggtaaacaa gtaaaagttg aagtgggaca
    50161 agcaatctat gttgaaaaac ttgacgttga agcaggagaa aaagttgttt ttgacgaagt
    50221 tatcttagta ggcggagaat ctacaaaagt aggcgctcca actgttgcag gtgcaactgt
    50281 tgaaggtact gttgaaaaac acggcaaaca aaagaaagtc gttactttca aatacaaacc
    50341 taaaaaacat tcacaccgta aacaaggtca tcgtcaacca tatacaaaag tggttatcga
    50401 cgcgatcaac gcttaatagc gtttgagaaa gaaggcctat atatgatcaa aggaacattt
    50461 aagcgaaatg acgcaggtca gatcgtttca ttcactttga ccgggcatgc tgatgctggt
    50521 ccttatggaa gtgatatcgt ttgtgcgggt gtttctgcgt tagcgatcag cactgtcaac
    50581 gggattgcct cattagccgg ttttgagccg attgttgaaa tgaatgaaga agaaggcggt
    50641 tatctttata ccgaagtcac ttcaggaatg acacaagaac aaaacaatat tgctgagatt
    50701 ctattagaaa atcttttatt aggattacaa tcgatagaag ctgaaaactc agaatatatc
    50761 caaattaaaa caattaatga taaataggag gtgcagacca tgttgttatc tatgaatcta
    50821 caattatttg cccacaaaaa aggtggcggt tctacatcta acggccgtga ctcagaatca
    50881 aaacgtctag gtgctaaacg tgctgatgga caaacagtta caggtggatc aattctttac
    50941 cgtcaacgcg gtacaaaaat ctatccaggt gtaaacgtgg gtatcggtgg agacgacact
    51001 ttatttgcaa aagttgatgg cgtagtacgt ttcgaacgta aaggccgtaa caaaaaacaa
    51061 gtgtctgttt atccagtagc tcaagaagct taattgaatc ttatgattaa agaggttgtg
    51121 acaagacttt tgtcacagcc ttttttgttt ataaaaataa aagttgtagt ggaggctacg
    51181 aagtttactt tgtcttttta cacttaatat ttttttgcca atttggaatc aggatgtttt
    51241 gataactatc gttttcaatt gatggaagct atattgtttg ctatcagtga aataattata
    51301 tggtaaacag tgttcttttt cttgtttcca ttataaaaat cgtatcggga tttttcgttc
    51361 ttttaaattg aacatttcta tctatccgcg tgttatcaac aaaacaaaat caggtaaata
    51421 gttgacgaaa cagaaataaa tacatagtat tatgttttga agcctaagta caatagtcta
    51481 tagaaaagga gcgataccat tggcaaaacg cattgaccga atttatatgt atgtcaaaga
    51541 aaaaaccgct catttaacaa aggcagaata tgatcaagga gtaacaacac aggaaattgc
    51601 tgaagtgtta gggattcagc gaacaaatag cagtaaagat ctgaatcagc tagtgcgcga
    51661 aggaaaactg ataaagacag acggacgacc agtacgttac atatatcaaa cactcgttac
    51721 gcacgtaaag ccagttacaa aacatgtagt cagttacaaa gaaacgccgg tctctgaaga
    51781 aaaaaataca ctccaaatag atactaagga tatctttgca aaaatcattg gagctaacgg
    51841 cagcatgaaa aattcagtgg aacaggcaaa agctgcgatt ttgtatccgc caagaggatt
    51901 aaattgtttg attacaggac ctaccggatc aggaaagact tattttgcac acgcgatgta
    51961 tcattttgca aaagcgcatc atgtaataga tgaggaaacg gaactgattg ttttcaattg
    52021 tgctgattat gccaataacc ctgagctttt gatgagtcat ttatttgggt acgcaaaagg
    52081 tgcttttaca ggcgcagatg aagaaaaaat ggggattatc gatcaagcgg atggcggtat
    52141 gctgtttttg gatgagattc accggttgcc gcctgaaggt caagaaatga tcttttactt
    52201 tatggatcat ggaacttaca gtcgtcttgg ggaaacaacg aaatcccatg aagcaaatgt
    52261 acggatcgta ggtgcgacca cagaagaccc aggttcttct ctattagaaa cttttgttcg
    52321 gcgtatccca atcaatatca aacttccggc ttttgaaaaa cgtcctgcaa atgagaaagt
    52381 cgatttagta aaaatcatga ttgcccacga agcaaaccgc acgcagcgaa agatttcttt
    52441 gacagaagat gtagcaaaag cattgatcgg cagtgtgacc tatggaaata taggacaatt
    52501 gaagtcaaat atccagttag tatgtgcacg aggatttcta aatcatatgc aatcacccga
    52561 aatctcgatc acaatcgatg atttgacaga agggattcgt agcggattga ttcaattagc
    52621 aagcaaccgc agtgcaatgg cagagctttc taaaatattg gagccaaaga taactgtagc
    52681 accaaatgat acgatcatga aaatccaatc ggactcctat gagttacctt ataatctata
    52741 tgatatcatc ggagataaag cagctttact gaagtcggat ggtttggatc aagaagcaat
    52801 caatcatttc atttctacag atatcaacat ccatctgaag tctttctata aagaccatgg
    52861 tttttctttt aatgcagaca gcaaattagc agaatttgta gatccgaaaa tcatagaagt
    52921 gaccaatcag atttatgtaa tggtcaaaag atctttacca tatgagtttc agcaaaactt
    52981 tatttatgct atgagcttgc atatcagttc ttttttgaaa aaaatcaact taggagaaga
    53041 acggcatacg aatgataaca tccgtgagat ggcttttgat tttccagatg aatatgctgt
    53101 tgcgaaagaa gtgcgtagtt atatcgaaac gtattttcaa gtggagattc cagaaagtga
    53161 agactattac ttgaccgttc tactcgtctc gttacgggca aatcaagcaa gcggcagaat
    53221 cggtgtagtc gttgcagctc acggaaacag cacagcaagc agtatggtcc aagttgtcca
    53281 acagttgtta gatgcagaga acgtacgagc agtagacatg cctttggata tggatccgaa
    53341 aacagcattg gaccgaattg aacgcaatgt acaagaagta gatgaaggaa gcggggtcat
    53401 actcttagta gatatggggt cccttgcgtc gtttaattcg caaattcaaa gagacactgg
    53461 aattccagta cgtactgttg atatggtaac aacttctcta gttttggaaa ctgtacgaaa
    53521 ggtctcagta ttagggacag atctagatat gttgcatgaa tcattgaaaa attttcgagg
    53581 ttacgcagaa atatcttctg tagaatctgt tcaggaagca aaacctattc ataagaaaaa
    53641 agctgttttg gctatctgcg catctggcga aggtacagca caaagaatca aagaattgat
    53701 cgaacgagcg gtaaacaagc gtcaagaaac agaattagaa gttctagctt tgtcgattgt
    53761 ggaagtgaaa gaagaactgc cagttatcca aaaagaatat cagatcatag ctactactgg
    53821 gattactgat ttgaatatcc aagccccatt tattccttta gaacgtttta ttgatcaaaa
    53881 tatcgaagtc attttggatc agttgctgat ggaatcagaa ttggaggaaa ctgaattcat
    53941 ctccctagat gaagagtcag ctaaaaatac gtgtgttgag tttatctctg ataacttcat
    54001 ctttattaat ggtagtaagt taatcgatcc aatgtggcaa ttttctacac aaatctctca
    54061 gacgacggga atcggcgatg aagaatatgg attcaaaatc aacctagtga tgcacacagc
    54121 aggaatgatc gaacgtatta ttcggaatga accattgact gtggaagaaa acgaattgac
    54181 aaatacaacg aatgatcctc tttatagcca attggcagcc tcagttgttc tgttggaaga
    54241 tcagataaaa gtaaaagtgc cgatagaaga aatgtattat ctgctacgtc tagtccataa
    54301 tcagttagat aaaaaagaat acactgtgcc atgaatacac aaaaacgata cacttttata
    54361 gtgtatcgtt tttgtgtatt ggttaagaat cctttaaatt caattagtgt atcgtaaaaa
    54421 agttggcacg ctttttgctt atagtagtgt gtgctaggag gtggttgttc acacagaaat
    54481 gataggggtt tctgtgaagt agtgaggaag aaggagtttt gcagatggat attcgattgg
    54541 cacgtataga tgatcgttta atccacgggc aagtcgcaac agtttggtcg aagcaaacag
    54601 gtgttgaacg tatcattgtg atcagcgatg tagtcgctca agataaattg agaaagtttc
    54661 tactaaaaga agctgcaccg ccggggatca cagcaaatgt aataaccgtg cagaaaatga
    54721 ttcaaatcta tcatagtgga ttattatcac gagcaaaagt gatgctttta ttcaccaatc
    54781 cccaagatgt tgaagcggtt gtccgctgcg gtgtacagtt gaagtcgttg aatatcggcg
    54841 gtatgagttt tactgaaggc aaatcaatga ttaccaattt tgtttcagta aatcaacaag
    54901 atattgattc ctttcgttac ttgaacagtc aagaagtgga gttagagatt cgaaaagtac
    54961 ctgctgacag gaaaatcctt ttgatggaac tactagcgaa aatcaaaaag gtgtagcaag
    55021 aatggttgtt ggaaaaggtc aaataattct gttgtaatgg ttagcaatta ttaatatttt
    55081 tgaatttgtt acaacaaaag taaataggag gtataaatat ggtagggatt atcctagcaa
    55141 gtcatggaca atttgctgaa ggaatcttac aatccggttc aatgatcttt ggcgaacaag
    55201 aaaacgtcaa agccgtgatt ttgaaaccaa gtgaaggtcc agatgacttg agagccaaat
    55261 tggaagaagc ggttgcttct tttgataatc aagacgaagt gttattctta gttgatttat
    55321 ggggcggaac accgttcaat caatcaaaca cattattcga agagcacaaa gataaatggg
    55381 caatcgtcag cggtttgaat ttaccaatgt tgattgaagc ctacgcatca cgcttttcaa
    55441 tggaatctgc tcatgaaatt gcagcacaca tcattgaaac agcaaaagac ggtgtaaaag
    55501 taaaaccgga agaattagaa ccggcagaag caccgaaagc agcagttgaa gacgcacaac
    55561 ctaaaggagc acttccagaa ggaactgtgg tcggagacgg aaaaatcaaa tatgtattag
    55621 cacgtgttga ctcacgtctg ttacatggac aagttgcgac agcttggaca aaagcagtgc
    55681 aaccaaaccg tattatcgtt gtttcagatg cagtatcaaa ggatgatctg cgtaagagac
    55741 taatcgaaca agctgctcct ccaggtgtaa aagcaaatgt tattcctatt agcaaaatga
    55801 tcgaagtagc aaaagaccct cgttttggaa ataccaaagc attgctttta tttgaaaatc
    55861 ctgaagacgt attgacagct gttgaaggtg gcgtagacat caaagaatta aatgttgggt
    55921 caatggcgca ttcggtcggt aaagtcgttg taagtaaagt attgtctatg ggacaagaag
    55981 acgttgaagc gtttgagaag cttgaacaaa aaggtgtgaa attcgatgta cgtaaagtac
    56041 ctaatgattc acgcgataac atggatgata ttttgaaaaa agcaaaagct gaattagcaa
    56101 aagcgtaata aataatatta aaatttatag gaggcttatc atgtctatta tttcaataat
    56161 tttagtcgta ttagttgcct ttctagctgg tatggaaggt attcttgatg aatttcaatt
    56221 tcatcaacca ctagtggcat gtacattgat cggtttagtt accggtaacc tcgaagctgg
    56281 tatcgtactt ggcggtacgc ttcagatgat cgctttaggt tgggcaaata tcggtgccgc
    56341 tgtagcacca gatgctgcat tagcatcagt agcatcagca attattttag ttttaggtgg
    56401 acaaggtgtt aaaggtgttc cttctgcgat cgcgattgcc gttcctttgg ctgttgcagg
    56461 gttgttctta acaatgatcg tacgtacaat cgctgttcca atcgttcatt tgatggatgc
    56521 ggctgctgaa gaaggaaaca tccgtaaggt tgaaatgtgg cacatcattg ctgtatgttt
    56581 acaaggggtt cgtatcgcgg tcccagcagc agcgttgcta tttatcccag cacaaactgt
    56641 gcaatcattc cttgaatcaa tgccagcatg gttaacagat ggtatggcta tcggtggggg
    56701 aatggtcgta gctgtaggtt acgctttggt aatcaacatg atggctacaa aagaagtatg
    56761 gccattcttc gttattggtt tcgttgtagc tgcaatttct caattaacat tgattgctct
    56821 aggtgcttta ggtgttgcat tagctcttat ttacttgaac ctttctaaaa tgggtggttc
    56881 atcaaataat ggaggcggaa gcaattctgg tgacccttta ggcgacattt tgaatgacta
    56941 ttaatcttga aggaggaaaa taaaatggca gaagaaaaaa tcaaattatc aaaaaaagat
    57001 cgtttagctg ttgcgtggcg ctctaccttc attcaaggtt catggaacta cgaacgtatg
    57061 caaaacggtg gctgggcatt ttctatgatt ccagcaatca aaaaattata caaaacaaaa
    57121 gaagaacgtt ctgcagcatt aaaacgtcac ttggaattct ttaatacaca cccatacatt
    57181 gcttctccaa ttttaggggt tacattggct ctggaagaag aacgtgcgaa tggcgcgcct
    57241 gttgatgatg tagcgattca aggggttaaa gtaggtatga tgggtccttt agctggtgtt
    57301 ggtgacccag tgttctggtt tacagtacgt ccaatgctag gtgcactagg tgcttcatta
    57361 gctatgggag gaaatatcct tggaccaatc atcttcttct taggttggaa cattattcgt
    57421 tgggcattca tgtggtatac acaagaattt ggctacaaag ctggttctaa aattactgat
    57481 gacctttctg gcggattgtt acaagacgta acaaaaggtg cttcaatttt agggatg
//
LOCUS       DADGKS010000012        54012 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.012, whole genome shotgun sequence.
ACCESSION   DADGKS010000012 DADGKS010000000
VERSION     DADGKS010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 54012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54012
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.012"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(334..942)
                     /locus_tag="JXV47_000784"
     CDS             complement(334..942)
                     /locus_tag="JXV47_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HAX1486844.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(948..1976)
                     /gene="vanB"
                     /locus_tag="JXV47_000785"
     CDS             complement(948..1976)
                     /gene="vanB"
                     /locus_tag="JXV47_000785"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HAX1486845.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKSAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGTFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            complement(1969..2940)
                     /locus_tag="JXV47_000786"
     CDS             complement(1969..2940)
                     /locus_tag="JXV47_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HAX1486846.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVGHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            complement(2937..3764)
                     /gene="vanW"
                     /locus_tag="JXV47_000787"
     CDS             complement(2937..3764)
                     /gene="vanW"
                     /locus_tag="JXV47_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance accessory protein
                     VanW-B"
                     /protein_id="HAX1486847.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGEPFSFWWLVRHA
                     DKDTPYKDGLTVTNGKLTTMSGGGMCQMSNLLFWMFLHTPLTIIQRRGHEVKEFPEPN
                     SDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKIIGQVSADKEPQALYKITNG
                     SIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKCKICYPLPESVDIQEENQ"
     gene            complement(3782..4588)
                     /gene="vanY"
                     /locus_tag="JXV47_000788"
     CDS             complement(3782..4588)
                     /gene="vanY"
                     /locus_tag="JXV47_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-B/VanY-G family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HAX1486848.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGRR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            complement(4759..6102)
                     /gene="vanS"
                     /locus_tag="JXV47_000789"
     CDS             complement(4759..6102)
                     /gene="vanS"
                     /locus_tag="JXV47_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HAX1486849.1"
                     /translation="MERKGIFIKVFSYTIIALLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPDFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQAQSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLTSTL"
     gene            complement(6105..6764)
                     /locus_tag="JXV47_000790"
     CDS             complement(6105..6764)
                     /locus_tag="JXV47_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance response
                     regulator transcription factor VanR"
                     /protein_id="HAX1486850.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            complement(7707..7892)
                     /locus_tag="JXV47_000791"
     CDS             complement(7707..7892)
                     /locus_tag="JXV47_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAX1486851.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            8037..8408
                     /locus_tag="JXV47_000792"
     CDS             8037..8408
                     /locus_tag="JXV47_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1486852.1"
                     /translation="MANIEDCPGFETFGADVKAARQAKRVSRKAMAEKINIDWRYLAN
                     IENDGAIPSLPVVIQLIKACGLPVERYFNPEIMREESELRQRVSHKLKLCPEEYLPII
                     EGAIDSAILIEKPKKNETEDV"
     gene            8666..8995
                     /locus_tag="JXV47_000793"
     CDS             8666..8995
                     /locus_tag="JXV47_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HAX1486853.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            8956..10284
                     /locus_tag="JXV47_000794"
     CDS             8956..10284
                     /locus_tag="JXV47_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAX1486854.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            10281..10652
                     /locus_tag="JXV47_000795"
     CDS             10281..10652
                     /locus_tag="JXV47_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486855.1"
                     /translation="MSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECICVQSI
                     SYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAACSKRM
                     RRRKEAERQRKRYWKPTHLEL"
     gene            10835..11071
                     /locus_tag="JXV47_000796"
     CDS             10835..11071
                     /locus_tag="JXV47_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1486856.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(11371..11574)
                     /locus_tag="JXV47_000797"
     CDS             complement(11371..11574)
                     /locus_tag="JXV47_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486857.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMLVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(11578..12522)
                     /locus_tag="JXV47_000798"
     CDS             complement(11578..12522)
                     /locus_tag="JXV47_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486858.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            complement(12523..16443)
                     /locus_tag="JXV47_000799"
     CDS             complement(12523..16443)
                     /locus_tag="JXV47_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HAX1486859.1"
                     /translation="MNEVFSIQVHNRQFLEQGKQGVWLDLPTTTETLQAALRDVGITA
                     DNPQDFFINGYSCPEDRHLAIPYDMVLAADVDELNFLAARLGQLDAAEIAELNAALQN
                     PRGGFENIGQIIDYTENVDYYVHLPDVRGDGQLGDYYLNRSGMVDMPEEWKAGIDTAQ
                     FGRHIAQQEQGVFTQYGYLVRSGDEWQRVHEGQPVPEEYRVMHYPQPEADREEPQAQQ
                     PEASESPDKAPPPVIPIMLDGMNSKERMKVITDRLETGVQELFESSRYMAYLSAMSKM
                     HDYSLNNTLLIAMQGGSIVAGYNRWQDEFDRHVKRGEKGIKILAPAPFKVKQQMEKID
                     PATQQPVIGADGKPVTEEQEVTVPAFKVVTVFDISQTEGKDFPMPYISELTGDVQQYQ
                     DFFAALERTSPYPISIEPISDGAKGRCFYAKQRIAINEGMSELQTLKTAIHEIAHAKL
                     HAIDREAPAEEQAARPDRSTREVQAESVAYTVCQYYGLDTSDYSFGYVADWSSGRELS
                     ELKASLETIRATASELITEIDGHFAQLQQEREARQEQEAVTVDVTPEAAAPAQAEEEQ
                     APALDPAAEPLVTVLWSESPQLKDGQQMPLHEADALFARLDAAYPAEAGYDKTAFRID
                     CIFQGEPDSYEGRQDFGDRDGSLIEHIQSYHQFYAQDENWKKHVIATTGIEGWEQDKA
                     HRDMLLGEFVPYMKLHCSLAQMEQTAQGRLQSGETLTPEETAYLGALLSYVQECRPML
                     NQGQYQLPEPPKLADFDQSLQDYKAQVQAEIAQEAAAAGMTVEEYAAAGYEAPQQDTF
                     SIYQLRGGEETRDYRFEPYERLQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNID
                     HPADFRGHSLSVSDVVVLHQNGQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNEN
                     MIDGIINNTPPEPQPEEPEQLSFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAAR
                     RAKEAMSFSDYRPGSATAEYRHYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLA
                     ENMNKGYEITARVPSVLIAGPSNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGM
                     GGISADDPQAVSKLEKKLEKLEASQELMKAVNAYYRKHGTLDGCPHLTERGIENLKAD
                     MASGWHYEKKPFQSWQLSNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVA
                     NRLQIFFEGKPDAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEK
                     PSALQLAARREKEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            complement(16592..18673)
                     /gene="topB"
                     /locus_tag="JXV47_000800"
     CDS             complement(16592..18673)
                     /gene="topB"
                     /locus_tag="JXV47_000800"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAX1486860.1"
                     /translation="MTYKLVIAEKPSVARSIAGVIGATEKHDGYLEGNGYLVSWCIGH
                     LVSFADAGRYDERFKKWRYEDLPILPETWQYIVPDDKKQQFDVLCSLMQRPDVTGLVC
                     ATDAGREGELIFRFVYQMAGCQKPFERLWISSMEDSAIKDGFAHLKPGGDYDPLYQSA
                     LCRAKADWLIGINATRLFSVLYHKNLTVGRVQTPTLKMLVDRDAKITDFKKEKYHIVH
                     ITAGGADAVSSRFSDAAEANTVKAACAKAQAVCVSVTREKKTEQPPKLYDLTTLQREA
                     NRLFGYTAKQTLDYAQALYLKKLLTYPRTDSQYLTDDMLPAVESLVSGLWELVPFAKG
                     LNLSPQFDRILNSKKVSDHHAIIPTAEFVKQGFGTLAESEKKLLSLICCKLLCAVAGP
                     HIYEAVTATFTCAGQEFTAKGKTVLSPGWKEIERRFRSSLKTDADEDAEAVRELPELC
                     EGQTFADVAASVTEHFTTPPKPYTEDTLLSAMERAGAEDMPEDAERKGLGTPATRAAI
                     LEKLVQMGFVQRKGKQLIPTKDGINLAVVLPEALTSPQLTAEWENRLTEIAKGQADPD
                     EFMDGIETQARELVQTYSCISEEKQKLFQAERVPIGTCPRCGEAVYEGKKNYYCGNRA
                     CQFVMWKNDRFFEERKKAFTPKIAAALLKTGKVKVKGLYSVKTGKTYDGTVLLADTGG
                     KYVNYRIEHRS"
     gene            complement(18670..19899)
                     /locus_tag="JXV47_000801"
     CDS             complement(18670..19899)
                     /locus_tag="JXV47_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HAX1486861.1"
                     /translation="MKNKTRRISRILPALLAVMLCVTAFPVTALAGGNDPAPAPLPEA
                     TTEPATGGLEPETDETGTATDGTETEAEKDTGPLTGKDITDLFSALFGSKVSIAATDD
                     GIQITTGTDKKEPEQTGTVTTNGGRLNVRTGAGLDKTAFTQLPNGTTVEVVGTDGDWI
                     KILLPERIGYVHSDYMTVSEKEVAATGEGGFSLSIDPEEIASLLELFNGGGASAALSP
                     DGNLSLIDDIGSAAKNGKQFITVETKNGNVFYLIIDRDDEGKETVHFLNQVDEADLLT
                     LMEDGETVTPAAVCSCTTKCKAGAVNTNCPVCKTNLTECSGPEPQEPQPEEPEAPEEE
                     PKGGAGGLIVFLLVALAGGGAALYYFKFKKPKAETTGSDDLGEYDFGEDEDLEDEEPE
                     TEFDPEADFVSEQEDEE"
     gene            complement(19889..20140)
                     /locus_tag="JXV47_000802"
     CDS             complement(19889..20140)
                     /locus_tag="JXV47_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HAX1486862.1"
                     /translation="MATKLDRIEKDIQKTKSKIAEFQKQLRELETQKTEQENLQIIQL
                     VRGMNMKPEEFAAFLRSGAMQAAPAATPYHEQEDNAHEE"
     gene            complement(20163..22154)
                     /locus_tag="JXV47_000803"
     CDS             complement(20163..22154)
                     /locus_tag="JXV47_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006060479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HAX1486863.1"
                     /translation="MKELKAKAKVTQAMTRDGLTLENQATGEVENISSREAEQDLSAP
                     GPGGTADKLLERADAIHDGHKAKKAAKQAGAVAAEGDAALHRPSARLQLSEEERADPD
                     LQPYIRKSDKRADKLDKARAAIPKKRVPVKETVFDEASGKAKTVLHFDKQDKGPPSLK
                     PNPAGRPVSEVFLFGHGKIHEVEHENVGVEGGHKGEELAERQAGKAIRSTIRHHRLKP
                     YWDAEKAERRLLSANAEYFYQKSLRDNPEIAQAASNPISRFWQKQQIKRQYAKAARTA
                     GQTAGAAAQGAAKTAGASTKAAKAAAKESERAASFVARHWKGALAVLVLGLLMLLIIG
                     GLQSCTAMFGSAGSGITASSYFSEDSDMLAAEDAYAELEAELQDYLDNYEATHDYDEY
                     HFDLDEISHDPYVLISILSALHDGIFTIGEVQGDLSMLFDKQYILTENVVVETRYRTE
                     TDTWTDAEGNTHTDTYQVPYDYYICYVTLENFDLSHVPVYIMDEETLSFYSLYMSTLG
                     NRPDLFSGSQYPNASTLTPPTYYDVPPEALEDATFAAMLKEAEKYIGYPYVWGGSSPS
                     TSFDCSGFISWVINHSGWNVGRLGAQGLYNICTPVSSSQAKPGDLVFFKGTYDTPGVS
                     HVGLYVGNNVMLHCGNPISYTNLTSNYWQSHFYSYGRLP"
     gene            complement(22186..24585)
                     /locus_tag="JXV47_000804"
     CDS             complement(22186..24585)
                     /locus_tag="JXV47_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HAX1486864.1"
                     /translation="MSKKEIPRETEKTKLTRAQRKEIDAVIRKYKGDGRPHTAQQSIP
                     YEVMYPDGVCRVSPGVFSKCIEFADISYQLAQPDTQTAIFEKLCDLYNYVDASIHIQF
                     SFLNRKVDPVQYAKSFEIAPQGDDFDDIRAEYTGILQKQLANGNNGMVKTKYLTFTIE
                     AESVKAARARLKRIGFDLLGYFKSMGAVAHVMDGWERLNLLHGVYHPDGEIFNFDWKW
                     LAPSGLSTKDFIAPSSLCFGNAKTFGMGGKYGAVSFLQILSPELSDDMLADFLNTESG
                     VLVNLHVQAIEQTKAIKTIKRKITDLDAMKIAEQKKAVRSGYDMDILPSDLATYGEDA
                     KKLLTKLQTRNERLFQLTFLVLNVADTKQKLNNDVFQAAGVAQKHNCPLVRLDYQQEQ
                     GLASSLPLGVNQIKIQRSLTTSSVAVFVPFVTQELFQGGAAMYYGINAKSRNMIMLDR
                     KQARCPNALKLGTPGSGKSMSCKSEIVSVFLTTPDDIFISDPEAEYYPLVKRLHGQVI
                     RLSPTSKDFVNPLDINLNYSEDDNPLALKSDFVLSFCELVMGGKNGLEAIEKTVIDRA
                     VRVIYRPYLADPRPENMPILSDLHKALLDQHVPEADRVAQALDLYVSGSLNVFNHRTN
                     VDIGNRLVSFDIKELGKQLKKLGMLIVQDQIWGRVTANRSQGKATWYFADEFHLLLKE
                     EQTAAYSAEIWKRFRKWGGIPTGATQNVKDLLSSPEIENILENSDFITLLNQASGDRK
                     ILAERLNLSTEQQKYIDNSEPGEGLLIFENVVLPFTNPIPHNTQLYKIMTTRLNEVAG
                     V"
     gene            complement(24515..24937)
                     /locus_tag="JXV47_000805"
     CDS             complement(24515..24937)
                     /locus_tag="JXV47_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HAX1486865.1"
                     /translation="MAYVTVPKDLTHVKSKVVFGLTKRQLICFSGALVIGVPLYFLTR
                     DYLTNSAAALLMVFAMLPGFLLAMYERHGQPLEVVIMQIIQCCFIQPKERPYQTDNTY
                     TALVRQYQMEQEVKAIVQKGNPKRNRKNKADPRPAKRN"
     gene            complement(24951..25493)
                     /locus_tag="JXV47_000806"
     CDS             complement(24951..25493)
                     /locus_tag="JXV47_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methyltransferase"
                     /protein_id="HAX1486866.1"
                     /translation="MLISTYNIIYADPPWRYDCKNVQGAAENHYSTMSIDELCALPVE
                     RLASKDCLLFLWATFPMLPEALRLIKAWGFSFKTVAFVWLKQNRKSLTWFYGLGRWTR
                     GNAEICLLATHGKPKRRSASVHQFIISPIEQHSKKPDVTREKIVELAGDLPRVELFAR
                     QKTPGWDVWGNEVECDLILT"
     gene            complement(25524..26387)
                     /locus_tag="JXV47_000807"
     CDS             complement(25524..26387)
                     /locus_tag="JXV47_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486867.1"
                     /translation="MISEIIEEWIKGILMDGITGNLSGLFDTVNAKVGEIAADVGRTP
                     QAWNSGIFNMLHSLSETVIVPIAGAILALVMCYELIQMITEKNNMHDFDSSMFFRWIF
                     KSAFAILIVTNTWNIVMGVFDATQSVVNQSAGVIIGQTSIDFNTLIPDLESQLEAMSV
                     GALLGLWFQTLVVGLTMNILSICIFLVTYGRMVEIYVVTSLGPIPLATMGNAEWRGMG
                     QGYLKSLLALGFQAFLIMVVVGIYAVLIQNIGSASDISGAIWGCMGYTVLLCFCLFKT
                     GSISKAVFGAH"
     gene            complement(26479..26694)
                     /locus_tag="JXV47_000808"
     CDS             complement(26479..26694)
                     /locus_tag="JXV47_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugative transfer protein"
                     /protein_id="HAX1486868.1"
                     /translation="MAFFNSAVTTLQTIVIGLGGALCVWGGINLLEGYGQDNPGAKSQ
                     GVKQLVAGGGVALIGVTLVPLLSGLLG"
     gene            complement(26771..28579)
                     /locus_tag="JXV47_000809"
     CDS             complement(26771..28579)
                     /locus_tag="JXV47_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003819036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HAX1486869.1"
                     /translation="MKPDVKKLLILNLPYLIFVYLFAKCGEAYRLAAGADLSGKLLHF
                     ADGFAAAFANPLPSLHLFDLCIGIAGAVIVRLVVYCKSKNVKKYRKGMEYGSARWGTA
                     KDIAPYIDPKFENNILLTQTERLTMTGRPKDPKTARNKNVLVIGGSGSGKTRFFVKPN
                     LMQCFPTTDYPTSFVVTDPKGTLVLETGRMFQQAGYRIKILNTINFSKSMKYNPFVYI
                     HSEKDVLKLVNTLISNTKGEGEKSAEDFWVKSERLFYSALIGYIWYEAPAEEMNFSTL
                     LEMINASEAREDDPEFQSPVDLMFERLEQKDPDHFAVRQYKKFLLSAGKTRSSILISC
                     GARLAPFDIREVRELMEDDEMELDTIGDEKTVLYLIMSDTDTTFNFILAMLQSQLINL
                     LCDRADDVYGGRLPVHVRLILDEFANIGQIPNFDKLIATIRSREISASIILQSQSQLK
                     AIYKDAAEIISDNCDSVLFLSGRGKNAKEISDALGKETIDSFNTSENRGSQTSHGLNY
                     QKLGKELMSQDEIAVMDGGKCILQLRGVRPFLSEKFDITKHPRYKYLADADKKNTFDV
                     DRFLTITRRKRQQVVTQDEVFDLYEIDLSDEDAAAE"
     gene            complement(28576..29052)
                     /locus_tag="JXV47_000810"
     CDS             complement(28576..29052)
                     /locus_tag="JXV47_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HAX1486870.1"
                     /translation="MQEEVTQKTIALSMKTGKLTAQVLQAALKKYLQHRAKGKNTLHH
                     GQQSLKQLKKHGADLSNIEITEANIGAFKPCAKKYGVDFTLRKDKTTQPPHYVVIFKA
                     KDADNLDLAFREFTAKTLSKEQRPSIRKVLSAVKQKAAAQTKQRAKEKIKERGLEL"
     gene            complement(29127..29339)
                     /locus_tag="JXV47_000811"
     CDS             complement(29127..29339)
                     /locus_tag="JXV47_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HAX1486871.1"
                     /translation="MKQGALIFDERTDRYDIRFDLADYYGGLHCGECFDVMIGGKWRP
                     TRIEMAENWYLVGIRADDLSGLRVRI"
     gene            complement(29361..30560)
                     /locus_tag="JXV47_000812"
     CDS             complement(29361..30560)
                     /locus_tag="JXV47_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1486872.1"
                     /translation="MLFTSGPDRAFERLMQEKPGFDHYDGGGADAPEDCGTCRFYRPD
                     WKYQFCQFAECPYQPGKLTDYAAVKFTVKGANNAMAVFRVEKNKGYTVMSNHHLRNKN
                     LTLKAKGLLSQMLSLPEDWDYTLKGLSYINRESIDAIRTAVWELEKAGYIRREQGRDA
                     KGKMADMVYTIYEQPVLENPVLENPTSDNPVLENPTSDNPASENPTQLNKEVQRTDLS
                     KKEKIITDGQSTHSIPIPSPTPAPMEGEAAATPPERKRTGKDEAVRIYREIILENIEY
                     AYLIQDRSIDREQLDEIVDLMLETVCTARKTIRVAGDDYPAELVKSKYMKLTGEHIRF
                     VLDCLRENTTKVRNIKQYLRAMLFNAPSTISNYYTALVAHDMAQPDWGKPKSGLPDYS
                     CGEGESL"
     gene            complement(30817..31338)
                     /locus_tag="JXV47_000813"
                     /pseudo
     CDS             complement(30817..31338)
                     /locus_tag="JXV47_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
     gene            complement(31354..32052)
                     /locus_tag="JXV47_000814"
     CDS             complement(31354..32052)
                     /locus_tag="JXV47_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAX1486873.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(32009..33670)
                     /locus_tag="JXV47_000815"
     CDS             complement(32009..33670)
                     /locus_tag="JXV47_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HAX1486874.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKR
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            33888..35288
                     /locus_tag="JXV47_000816"
     CDS             33888..35288
                     /locus_tag="JXV47_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HAX1486875.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKVLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIIGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(35540..36619)
                     /locus_tag="JXV47_000817"
     CDS             complement(35540..36619)
                     /locus_tag="JXV47_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAX1486876.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(36705..37664)
                     /locus_tag="JXV47_000818"
     CDS             complement(36705..37664)
                     /locus_tag="JXV47_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HAX1486877.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(37676..39199)
                     /locus_tag="JXV47_000819"
     CDS             complement(37676..39199)
                     /locus_tag="JXV47_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAX1486878.1"
                     /translation="MDEEVKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHE
                     TADGDGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIE
                     PNSFGLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQ
                     KKPFGVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPR
                     LPSYPEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFD
                     RQIEEIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMED
                     TLLFGSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAK
                     GQVLKQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLL
                     DQGEHYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(39209..39772)
                     /locus_tag="JXV47_000820"
     CDS             complement(39209..39772)
                     /locus_tag="JXV47_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HAX1486879.1"
                     /translation="MKIVETKFYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(39778..40641)
                     /locus_tag="JXV47_000821"
     CDS             complement(39778..40641)
                     /locus_tag="JXV47_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAX1486880.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(40655..41551)
                     /locus_tag="JXV47_000822"
     CDS             complement(40655..41551)
                     /locus_tag="JXV47_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1486881.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(41726..42997)
                     /locus_tag="JXV47_000823"
     CDS             complement(41726..42997)
                     /locus_tag="JXV47_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAX1486882.1"
                     /translation="MKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTLTFWNGF
                     TASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFIALNYPD
                     FAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMYMYWNND
                     LFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLANGGKLV
                     NDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIEINGPWL
                     NNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFLKYWNTT
                     EIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQISAINNDI
                     INPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(42987..44504)
                     /locus_tag="JXV47_000824"
     CDS             complement(42987..44504)
                     /locus_tag="JXV47_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAX1486883.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            44702..45592
                     /locus_tag="JXV47_000825"
     CDS             44702..45592
                     /locus_tag="JXV47_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HAX1486884.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(45665..46489)
                     /gene="nadE"
                     /locus_tag="JXV47_000826"
     CDS             complement(45665..46489)
                     /gene="nadE"
                     /locus_tag="JXV47_000826"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HAX1486885.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(46501..47973)
                     /locus_tag="JXV47_000827"
     CDS             complement(46501..47973)
                     /locus_tag="JXV47_000827"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HAX1486886.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(48610..48972)
                     /locus_tag="JXV47_000828"
     CDS             complement(48610..48972)
                     /locus_tag="JXV47_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAX1486887.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            49195..49947
                     /locus_tag="JXV47_000829"
     CDS             49195..49947
                     /locus_tag="JXV47_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAX1486888.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWLSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(50087..51010)
                     /locus_tag="JXV47_000830"
     CDS             complement(50087..51010)
                     /locus_tag="JXV47_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAX1486889.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYQKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(51025..51297)
                     /locus_tag="JXV47_000831"
     CDS             complement(51025..51297)
                     /locus_tag="JXV47_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486890.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
     gene            51974..52204
                     /locus_tag="JXV47_000832"
     CDS             51974..52204
                     /locus_tag="JXV47_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486891.1"
                     /translation="MMEDFIRKNISDEYADFYEQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            52210..52509
                     /locus_tag="JXV47_000833"
     CDS             52210..52509
                     /locus_tag="JXV47_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486892.1"
                     /translation="MLFNETQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(52545..52916)
                     /locus_tag="JXV47_000834"
     CDS             complement(52545..52916)
                     /locus_tag="JXV47_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486893.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(52918..53319)
                     /locus_tag="JXV47_000835"
     CDS             complement(52918..53319)
                     /locus_tag="JXV47_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486894.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            complement(53333..53740)
                     /locus_tag="JXV47_000836"
     CDS             complement(53333..53740)
                     /locus_tag="JXV47_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486895.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
BASE COUNT        13668 a        13133 c        11789 g        15422 t
ORIGIN      
        1 gaggggcaag gctttttttg agtggtggaa gtggattaga gcatggcaat agcaaaacag
       61 catagcggca tcctcctatg ggccgccaca ccttttgctg ccagaaaaga acggcggcct
      121 tgatttctca aaaccgccgc cagcaaaata caaaatgggc gtgggaaagg tctgcccaac
      181 agcggttttt ttcttttctg ccgctgggca gattgaatac tataatttgc aatgtattac
      241 aaaagatgct ttaaccactt tccagtaaaa gattgtccat gaccagcata gattttatca
      301 aatccaaaat ctgatacaaa accaatactt tcattatgaa acggcaaaat taaaataggt
      361 atcggggtat ggctcatcaa tcaacttata gtgccaccat tcaaagcgat aagactgaaa
      421 tccgctgctt tccatgattt tacgcaagca tcttcgattt tgtgcctctg catcccctat
      481 cccttttgct gtatgatgcg accgttcgtc cataaaatcg aagttacttc ccattgaaac
      541 aagttcccct gtatccaggt ggtagagcgt aagatcaatt gcgcttccac ggctatggct
      601 ggattgtgag gccacataac cctttgtaat caactcggct cgctctatat tggggtaaaa
      661 tttttctttt gtgagattgt cctccggttg cgctgcccaa cgcaggaagc agtccaccgc
      721 agttcttggc cgatatccat cccataaaag caagccatag ccaagcgcag ccgcatggat
      781 ttgtgcctcg cgcagagcaa acgccacggc ctttgtgccg atgatgcgat tcacctcata
      841 cccatccacc ggttttcctg tgaagttatc ccatgtggcg tacttggcat cccaacggac
      901 gccatgcaac atttcatcta aaaacaaaaa accattttcc atacttatca cctctttaac
      961 gccaatgtaa tcaggctgtc aatcagtgca ggaagcgtga ttcctgcggc ggccatcata
     1021 cgtgggtagc ggctgtacga tgtaaaaccg ggcagggtat tgacctcatt tagaacgatg
     1081 ccgccatcct cctgcaaaaa aagatcaaca cgggcaagcc ctctgcatcc aagcacccga
     1141 tatactttct ttgccgtttc ctgcacccga tttcgttcct cgaccggaat gtctgcggga
     1201 actgtaatca tcgcattttc tgagcctttt tccggctcgt tttcctgatg gatgcggaag
     1261 gtaccgtggc tcagccggat ttgatccact tcgccgacaa tcaaatcatc ctcgttcccc
     1321 atgaccgcac acccgacctc acagcccgaa atcgcttgct caattaagat ttttccatca
     1381 tattgtcctg ccgcttctat cgcagcgtta agttcttccg taccgtttac tttggttacg
     1441 ccaaaggacg aacctgaccg tgccggcttc acaaagacag ggtaggtaag cgcacccgcc
     1501 tccggcttgt cacctttatc aatcatttga aattcgggaa cggcgatgcc cgcatttttt
     1561 gtaagaatgt aggccagtga tttgtccatg caagctgcgg agctttgaat atcacagccc
     1621 acatagggga taccagacaa tacaaacagc ccctgtatcg caccatcctc cccgcatttg
     1681 ccatgcaaaa ccgggaaagc cacatcaata cgccgtgttt cgtattcgct ttctttcatg
     1741 acaagcagcc catgcgtttt cctatccggg gagagtatgg cggggagact gtcggcttcc
     1801 cattccgtac atggcttctt gcatagcttc catacaccgt tttttgtaat tccgatgtag
     1861 tgcggatcga atttttccgt atcaatgttc gcagcaattt ctattgcgga ttttaccgac
     1921 acatcatgtt cctccgagca accgccgaag atgattgcga cttttattct attcatgctg
     1981 taaactcctt tcaaaattga gacaattcct gattgttttt tctgtagtat cctgcagcac
     2041 acgctcagtg tagtacgccg tatggggtgt gatgatcaca ttcggcatcc ttaaaagctg
     2101 cgacaaaaag ggatggtcaa gcactttctg cgagcaatcg gtataaacaa actgatcctc
     2161 gccctccaac acatccagtg ccgcaccacc cagctttccg ctttccaacg cctccaccag
     2221 cgccccggta tcgacaagcg ctccgcgccc ggtgttgatt aaaaatgcgc cttgcttcat
     2281 ctctccaatt tgcttctgac cgatcagatg gcgggtatcc gcacaaagcg gcacatggag
     2341 cgtaacaata tcgctgtttt ttagaagctc atcaagctgg acataatctg catccatttt
     2401 tcggctgtta tcataggcca gcacatggca tccaaatccc cgcagccttt tgacgaccgc
     2461 ttgcccgata tggccggttc caataactcc cacagtcata tcccccagtt ctttcccccg
     2521 gatacgatcc aatctgaaat cttgttgcgc cacggcgtgc atggtgggtt ttgcaccccg
     2581 tatggccatc agcatcagca tcaaagcata atccgcaacg ctgtccggcg aatacgcaac
     2641 cgtgccaacc gagattccca ttctctcggc ggcagtcgta tcaatgtgat cgcagccgat
     2701 gctgcgggta gaaatgtatt ttaccccgac ctttctcagc gcaagaattg tcgcctcgga
     2761 aacctcggac ttatggccta cgctaacgca ttgattgcca gcggccaatt ttgcgttgtc
     2821 tgccgatatc gcatcgctaa tcagcgtagg gataatatga aaatccggcg ataaagcgcg
     2881 gaaagcattt gcctcatcct gttcgcatcc aaaaacagta atgcccacac tttttctcat
     2941 tggttctcct cctgaatatc cacactttcc gggaggggat aacagatttt gcatttgttt
     3001 gtataaagca gcttgcaatc tattatttcc ccggtaccta aggcaacttg catccgttta
     3061 acctgggcat attcataaat cccgccactt tcacggacat actggatact gccatttgta
     3121 attttgtata atgcttgggg ctctttgtcg gcggacacct gaccgatgat tttctcatca
     3181 tctaaggtca cccatatttg gtaggtgcag tcggtatcgt ttcgcacttt taaatcaatc
     3241 cagccctctg aaatggttgc atccacccct ttaatctcgt cactgtttgg ctctggaaac
     3301 tcctttactt cgtgacctct gcgctggata attgtcaatg gcgtatgcag gaacatccaa
     3361 aatagtaaat tgctcatctg gcacataccg ccgcccgaca tggtggtgag tttaccattg
     3421 gtcaccgtaa ggccgtcttt atagggggta tctttgtccg catggcgtac cagccaccag
     3481 aaagaaaagg gttcccccgg tcttatcaat aagccgttta aggtctttgc tgccagcttt
     3541 aagttgaaca ccttgttttc ctggtatatc atgtcaaatc cggtattgtg gttgtataat
     3601 gcgcaatccg tttcaaagag caaatgggaa agcgattttt cccctatcgt ctgcgcatag
     3661 cgacagccgt caaatctcat tcccgcataa aagcacattt ttctctgcgc ccgtctcatt
     3721 ggaagcagga acgggaaacg ctgtgtcaat ctttttctgt ccataacata acatcctttt
     3781 ctcatttttc tggttttaaa tattcctcaa ggcaaacccc ttggttgtac atctctgtgg
     3841 cagcttcgat gccaacatat cggtaatgcc acggctcgtt gctcacaccg gttatctctg
     3901 tcttgtctgg tgggtagcga cgaataaaac caaaacgata gctgttttca tccagccatc
     3961 tataaacctc gttgcctgtt gaatgaattc cgtccgcatt gatatccaca gcaagaccaa
     4021 gctgatgctc gctcgttccc ggcacggcca cccaagtttc tgcttccgct ttagcctgtg
     4081 cagaggtgta gcctttcgcc ttatattcgg caattttttc atccataatt tcttgctgtt
     4141 tttctgttgt tcggtatccg gatgcgacaa tcgggtaaac tccatcagtt cttgcggcat
     4201 caaacaaatc ttgaagatag ggagaaatcc gaatatctat ccgctcacca tttgatagtt
     4261 gctcaagctc cacatcgtac tgtgcgggga tggggttctg cctgttcact aaaatcaggc
     4321 tccattcctg ttcatctccc tgttctttgg cggtggcaag agcgttttcc tccaaattct
     4381 ccactacgtc agtgctgctg cctgtatgag ttgcagggat gggcggtatc tgtgttgcct
     4441 ccaatacgga agccagtctc cgccccaaaa acagcgtgca gactgtgaac gaaataatga
     4501 acgcacatag aaaagcccgc ttttccacgg attgtttcat atgccgtttg tgatgatccg
     4561 cattggaatg atagttgctt ttttccattt gatcgaatgc ctcctttgca ataaaactac
     4621 gatttgtggc tggtacgatt gttattatgg caagcgcatc tgtactttcc ctgtagccag
     4681 tctgtagttt tcctgtagca gcaaaaaaag accggcaggg ttatacctgt cggtcaaaat
     4741 catttaagtt ttaaatattt acaatgttga tgtgagcggt aaatccagcc agaacaaaac
     4801 gccatccgag gtgttttcca gcgcatactg gaggctcatg gcatccagcg ttttttgtac
     4861 gatggcaagt cctaaaccgc ttcgcccact ttttctgctt tgcgcctgat caatgcgata
     4921 gaatggggtg aacagccttg gaagcgcagt atcatcaatg tgaacgccca tgttcaaaac
     4981 aaaaaggcgg catttttcag caccaggctc actccatatc cgtacctcgc ctccctgcgg
     5041 cgtgttctga actgcattca atatgacatt ggatagtgcc ttttggagca gcctcggatc
     5101 ggacaggaca atttgcccgg ctggaatatc tgtgacgaac cgctggttgt ttgcctctgc
     5161 caaggtttga aaatcgggca gcaactcggc aaccgtgcgc cctatgtcca acggttcagc
     5221 tatgggtacg attctcccat cattcaggct gacaagctcc agtatttcgg aaatgatttt
     5281 gccctgccta tccatcattt tgatgcattc gcgcagatac ttagaatgat ctttgtagtc
     5341 accgatattt tcaagcattc cctccaacag aacgcttgta gccgcgatgg gcgtttttag
     5401 ctcatgagaa gctgccgcaa agaaatatcg ctgtgtttcc tccaactcat gttcccttgc
     5461 gatttcatcc tccagccttg cgatggtttc tttcagcctg acatacatgg aatgcatatc
     5521 atgagccagt gcgccaagct catcctttcg ctccagcggc ggcggtacat ctttcaggtt
     5581 tgccatttta ttcgcactgt ccgctaaggc tttgatcggc gttgtcattt gccgcgcaaa
     5641 gatatacgcg cataaaaggc tgaatacaac cattatcgca atcataacaa ttccccgaat
     5701 tgtcagccct tgataaagca atcccacacc tgccttgctt tgagcaacaa tcgaaatatt
     5761 atcatctcta tgtaccacat aaagaaagtc gggtctaaaa ctatttgatg tattggcatt
     5821 tggtgtggca tagagtacgc ttccctcttt atcttcaata taaaactcaa aggattggtt
     5881 attgtagtga aacagccctg ccacctcttg aatatcaagc ctatcgctat tctgaatcag
     5941 ttccaccaat ggctgatagg attttactgt ttgctgtaat tccatcactc tgaaataaga
     6001 cacaaattgc tgtgcaaaca gtgttgctgt tacaccgaca agcagtagca gggcaatgat
     6061 cgtataggaa aaaaccttaa tgaaaatccc ttttctttcc attattatga ttcctccaat
     6121 cggtatccta caccgcgaat ggttttgatg atattttccg gcagcttggc ccgcaaattt
     6181 ttgatatgag tgtggactgt gctgccatca ccctcaaagt catatcccca tatacgtgac
     6241 aaaatgattt catgcgttaa ggttctgcct ttgttctgca ccagcagcaa aaggatttca
     6301 aattcttttc gtgtcagggg cagctctgta ccgtcacaaa gtaccgtgaa atcctccggc
     6361 agaagtgtca gcctgccgac acggatttcc tttgccagcg caccgctgcg ccgcagcagg
     6421 gcttccaccc gctttagtaa aatctgcatc ttgaatggct ttgttacata gtcgtctgcc
     6481 tctgcatcaa acgcccggat ttggttttcg tcatccgaca gggctgtcat catcagaatg
     6541 ggagtatcat ttttcgcacg aaattcacgc aaaagttcat gcccgttcat accgggcagc
     6601 ataatatcaa gaataaccag ttgataagtg ttttcgtaaa acttggtgta tgcctcattt
     6661 ccatctgtgc aggcatccac ctgatatcct gcctcagcca gaaacgccct tactgtatta
     6721 cagatatgat catcatcctc gacaagtaga attcgtatcg acataaaaat ccctccattt
     6781 taagaagata acataacagt ctgtagtttc cctgtagttt caaagcgatt tcttttcgga
     6841 ttttaatcat ccgtcattgg gatactcgct tcttttcatg gtgtatgtat ctatattatt
     6901 ggtttaaacg aattaaatca agataataat aattaacacc ttcttaatgt ttgggatgtt
     6961 tcgattacag cggttgtcaa aacatcccga taatactggc aagcaatgga tcagaatatc
     7021 ctttacggat attctgatcc accacttgcc cgcctgcggc gttctcgttt tgcttgttgg
     7081 ggacacccca agcctcagca aaatgcgcgg cctctttttt gcgaatgcac cttgcggtat
     7141 ggcttttcac acaggcaggg cctgtgtgta ctccctccgg tcgctcttgc cgcactccgc
     7201 gcagcagatt cagtcctaat accgttcaag acagtagaaa atcagcaagt ctatattcct
     7261 catatcttca tcatccgtgt ccttgcagtt acaggaaatg taataatcgc caaatgtaaa
     7321 tcccagaata ttttcctcaa aaagccgtac ctccccggta ttaaaatcaa tcaccccata
     7381 ctcaaaggcg cattagacca gcagttatcc aatgtctgga gacttcacca taaagaatcc
     7441 agatgccggc cttttcaatt ctaccatata cggctgatac agcagcagct tcctcgtctt
     7501 tgtttcgggc attttccatt tctgtcatga taaagtttcg cttcttcata catccatgtg
     7561 taaatctttt ctttctgttt cagatgagaa tactttttat cggtctggag cagcctgcca
     7621 tctatcatct tatagttttt ccgtgacaaa ataccatgct ttctctctct tcaaaaccat
     7681 atccaaaatg cgccggtttc attatactat tcagtaaccg cctttccttt ctttgtacgc
     7741 ctgtcaatcg gcttttccgc agttttggga atgagccaga tcgtcgccat ctttacagcg
     7801 ccggggatgc gtcccgcagc acaatagtag tttatccatc gtgggggcac accccatttc
     7861 tcgcctgcct ctttcaacgt catgtagtcc atagtacacc tccacagggt acattataat
     7921 tcttttgctc gaagaataaa agaaacaaaa tgtgaaatat aaactttaag aaaggtgcat
     7981 ataccaacat tccacgggca gagtatgaaa tatacaatgt aagtgggagg tgcgatatgg
     8041 cgaatattga agattgtccc ggctttgaaa ctttcggcgc ggatgtgaaa gcggcccggc
     8101 aagcaaagcg cgtttcgcgc aaagcaatgg cagagaaaat aaatattgac tggcgctatc
     8161 ttgccaacat cgaaaacgac ggggccattc ccagtctgcc ggttgtcata cagcttatta
     8221 aagcctgcgg gcttcctgtg gaacgctact ttaacccgga gatcatgcgg gaggaaagcg
     8281 aactgcggca aagggtcagc cacaagctga aactctgccc cgaagaatac ctgccgatca
     8341 tcgagggcgc gattgacagc gccatactaa ttgaaaagcc gaagaagaat gaaacggagg
     8401 atgtgtaact ggcatcctct gttttacttt tagcgggagc tgcacagcgt agcttctatt
     8461 tttttgcact tttttctttc cagagggcta ttttgcgggt agtttggggc tttggaaacg
     8521 tcttgttagt ggagaaacag taacgtagca agcataggga gtgtagccac tcccggaaaa
     8581 acggcctgcc ccgtccctgc cgggccgcgt ccgttttgct tgttggggaa atccccaaac
     8641 ccctgaatgg aaaggacggt gaagcatggc aaacagaaag cgaaaaatcg tgctgcgcgt
     8701 ccctgtgacg ccggaggaac gggctatgat tgaacagaaa atggcgctgc tgcatacgaa
     8761 gaacttttca gcctacgccc ggaagatgct cattgacggc tatatcgtca acatggacac
     8821 cagcgacatc cgggcgcaga ccgccgagat acagaagatc ggcgtcaacg tcaatcagat
     8881 tgcaaagagg ctgaacggta tggggccggt gtacgcacag gacatcgagg atataaaggg
     8941 ggcgctggcg cagatatggc agttacaaag atacatccta tcaagtcaac gctgaaaaaa
     9001 gcccttgact acatcgagaa cccggacaaa actgacggca agctgctggt ggcctccttt
     9061 gcctgctctt atgaaacagc ggacattgaa tttgaaatgc tgctggcgca ggcataccaa
     9121 aagggcaata atctgggcca ccacctgata caatcctttg cccccggcga agccacgccg
     9181 gaacaggccc atgagatcgg gaagcagctt gccgaggaag tgctgcaagg gaaatatccc
     9241 tatgtgctga ctacccatat tgataagggc cacgtccaca atcacattat tttctgtgcc
     9301 gtggatatgg taaatcagcg caagtacatt tccaacaaac agagctatgc ctatatccgg
     9361 cgcaccagcg acaggctgtg caaggaaaac ggattgtccg tggtgaagcc cggccagagt
     9421 aagggcaaga gctatgccga gtgggacgcc cagcggaaag ggacgagctg gaaagcgaag
     9481 ctcaaagcag ccattgacgc cgctatcccg caggcaaaag attttgatga tttcctgcgg
     9541 ctcatgcagg cgcaaggcta tgagatcaag ccgggaaagt ttatttcttt ccgcgctccc
     9601 ggacaggaac gctttacccg ctgcaagaca ttgggggaag cctacaccga ggaagccatc
     9661 aaagagcgta tcaaaggccg cgttatcacc agagcgccca aagagcgcaa ggggatttct
     9721 ttgcggattg atctggaaaa caacattaag gcccagcagt cggcaggcta tgagaggtgg
     9781 gcgaagctcc acaatttgaa gcaggccgca aagactttga atttcctgac tgaacatggg
     9841 atagacacct acccggattt ggaaagcaaa gtggccgaga tcaccgccgc cagcgacgag
     9901 gccgccgcta ccctcaaagc tatggaacac cggcttgcgg atatggcggt gctgataaag
     9961 aatatttcta cctacaagca gctctggccc gtggctatgg aataccgcaa tgcagcggat
    10021 aaggcaaaat tccggcgtga gcatgaaagc acgttgattt tgtatgaagc tgcggcaaag
    10081 gccctaaagg gacagggtgt gaaaaagctc cccgatctgt acgccctgaa agccgagtac
    10141 aagcgattgg ccgaggaaaa ggaacggctg tatgagaagt acggcgaagc gaaaaagcag
    10201 atgcaggaat acggcatcat caagcagaat gtggacggca ttttgcgtat gacgccggga
    10261 aaggaatgga cgcaagagct atgagtattc cacgaatgaa ttaccctcaa tatcgcaagg
    10321 cccggaagct gacgcatgag tgctgcaact attgtgacgg caactgcctg ttgctggacg
    10381 acggcgaaga atgtatttgc gtacagagca tttcctattc gcttctgtgc cgctggttta
    10441 aggccgctgt cctcccgctg gatgcggccc tgtatgccga gatcaccaaa gaccgggacg
    10501 aagtgaaacg ctgctgtgag tgcggggcca cgttcacgcc gaagtctaac cgggccaaat
    10561 actgcgcggc ctgctccaaa cggatgcgcc gccgcaaaga ggccgagcgc cagcggaaaa
    10621 gatactggaa acctacgcac ttagagctgt aaaagccctt atatttcaag gcttttccgg
    10681 catggtcagc ggggtatgtg ggtgttttat cctatccccg ccgaagtgct gttctaaatg
    10741 cgtagaattt accagcagaa aagcgccgtt ttctctggtt ccatgcttcc gaatatggta
    10801 tcatagaaaa aatcagtctg acgggggtat caggatggac ggacaagaaa agctgctgga
    10861 ctatgaaacg atcaaagccg ccgttgccgg tgagaggtgg gccacggaaa aagtgttggc
    10921 ccattatgct gactacatca acgagctttc cacggtggag atcagacagg caaacggcaa
    10981 aaagaagaaa gtcattgacg aagatatacg gcagcgcatt tccctgaaac tgctggaagc
    11041 attgccgagc ttcccgctgg aacagagata gacggcaaga gggctgcacc ctcttacgcc
    11101 gctttgcggc tatcacctgc acacccctga aacagataca cccgctgcgc ggctatatct
    11161 gtttcagggg tctaattata gctgcaacct acgcatttaa gggattgaaa accgcccgct
    11221 gcaaggcttc tcccgcatgt ttgcaggggc aagcgaatac ttcatcctat ccccgacaat
    11281 accgggttct aaatgcgtag gaataggcaa aaagaaaaga cgccggacgc aagcgaccac
    11341 atggccgccg cgcccggcgt ctgctgttcg ttattcgtct gtgaagtgga acttctggcc
    11401 gtcatagtcg gcatccgtca tgcgttccag cttggaaagg gtctgctggg cctgcgcccg
    11461 catatcccca tccataacca gcatgacggc ggtgagcctg tttatcgttc tgcgccggtc
    11521 tgcattgtgg tacatacaga tcaggttttc ttcctccacg gtaaagtgca tcattcctta
    11581 tacctccaat tcattctttt tggttctggc cgccgccttt tttgggctgg cggcctgttt
    11641 gctgtcggat agctgcttgc ggatagaggg ccggggcctg cgaatactca catcccggcg
    11701 ctcgtcccgg ttaatcacgg catacacgcc atgcctgcct ttcatcccgg taaaacacag
    11761 ggatttatag ggcagcatgg caaagagccg gtcattatcc ttggtggaag caatcgccgc
    11821 aaagtgcggg gagatctcca ccatgaaatg cgttttattg gggctgttag gcgcggacag
    11881 atctttcagg ctgtccacaa tacgccgggc ctcggtttca atccggctgt catgcaaagc
    11941 ggtgacgtgg actttgaaat cgccggggac ggcccgcccc cggctgtgct gctccgtccg
    12001 tagcgcctcc tgcagcacag ccgggtcatg gggctgggcc tcatagtaca aaaagtttcc
    12061 caatacccgg tcagggcttc cgtcaaaacg ctggctctcc gggatgtcac gggtgccatg
    12121 ctcataaaag agccggttca cactcaccgg ctgggcggtt tcaatgacgt gccggaaatg
    12181 ctgcggatag tccagctcat agagattgcc ccggatagtg ccgccctgtg tgccggtcag
    12241 ctccaccgcg taggccagta tcttgtcacg ggtctgctcc ccgtaaaatt tccatgtgtt
    12301 gtactgtcgg gtgtctttca ggaaaacatc acgttcccgg aaacagtacg tcccggaggg
    12361 ccgggacatc cagagcaggg tcttgtctgc ggcctgatcg ctggcggcat cccgcctgat
    12421 aatgtctttg tcaatgccaa agtcactttg ataaaacgcg gtgttctgcc gcatgatctg
    12481 ttccagcgcg gccagaacgt ccacattttc aaacttctgc atttactcta cctccaatcc
    12541 ctttgatttt tcccgcgccg gtggctgctt ggcctgttcg gtcttggccg cgttgagctg
    12601 cgcccggata gagggctttt ctttctccct gcgggccgca agctgtaagg cgctgggctt
    12661 ttcgccggaa aggggctgga tgcacttgat acggtcagcg acgcggattg tggtgtcgtt
    12721 taactgccgc tgccatgccc cggccttggg cgaccagcgg aaaccgttgc ttttcagctc
    12781 gtcgcgtaca gcagcatccg gcttcccctc aaagaagatt tgcaggcggt tggccacccg
    12841 gttgatctcc acagtgccgc cgtcaaactc ccatcccaca taggccgcct ccttttggcg
    12901 ggtcaattcc tcaatgcggc cctttaaccg gcgtatctcg gcgttattgt tggagagctg
    12961 ccaggactgg aacggttttt tctcatagtg ccagcccgac gccatatccg ctttcaggtt
    13021 ttcaatgcct ctttcggtca gatgggggca tccgtccagc gtcccatgct tgcggtagta
    13081 ggcattgacg gccttcatca actcctgcga cgcttccagc ttttccagtt tcttttccag
    13141 cttggaaacg gcctgcggat cgtcggcgct gataccaccc atgccggtgc tgcggatttt
    13201 gtcaagcaag ccctgaatgt actgaaattc ctccatgttg cggtcactgg cggcgttctg
    13261 cttttctttc gcccgtaccg ggaaattgga cggcccggca atcaggacag aggggacgcg
    13321 ggcggtaatc tcatagccct tattcatgtt ctcggccagc ttgcgggcgt aggtgtcaag
    13381 gaggctgtct atcttttcgt gatactctgg ctccacacgc tttttctggc gctccgcaat
    13441 ttccacggcc tgatcgacat agtgccggta ttccgccgtg gcgctgccgg gccggtagtc
    13501 agaaaagctc atggcttcct tggcgcggcg ggcggctccc tcattgatgg gataatagcg
    13561 gacagccgtt tgcgggggcg cagcctccgg gggttcctcc tgtgtctggc cggaagcaac
    13621 tgccacatcc tcaaaagata gctgttcggg ttcctccggc tgcggttcgg gcggcgtatt
    13681 gttgataatg ccgtcaatca tgttttcgtt ctgctccgta gacagttcgg cggtacgcag
    13741 gggattttcc cgcaaaaact ccggcacttc catatagccg aagctgtcta catagtgggc
    13801 ggtgtcctgt ccattctggt gcagcaccac cacgtcggaa acggaaaggc tgtgtcccct
    13861 aaaatctgcc gggtggtcga tgttgaatgt gcggtaaata tcctccaaag acgtgctttt
    13921 atccagcggt gccgtataaa caaggtcata gttggcactg tccacggcca gccctgcggc
    13981 ctgtaaacgc tcgtatggct caaaccgata gtcgcgggtt tcctccccgc ctcgaagctg
    14041 gtagatggaa aaggtgtcct gttggggtgc ttcatagcca gccgccgcgt attcctccac
    14101 ggtcataccg gctgcggcgg cctcctgcgc gatctcggcc tgtacctgtg ctttgtagtc
    14161 ctgcaagctc tggtcgaagt cagccagttt cggcggctcc ggcaactgat actggccctg
    14221 attgagcatg gggcggcact cctgcacata agagagaagc gcccccaaat aggccgtttc
    14281 ctccggcgtc agggtttccc cggactgtaa gcggccctgc gccgtctgtt ccatttgggc
    14341 aaggctgcaa tgcagcttca tataggggac aaactcgcct aacagcatat cccgatgggc
    14401 cttgtcctgc tcccagccct ctatgccggt tgtagcgatt acatgctttt tccagttttc
    14461 gtcctgcgcg taaaattggt ggtagctctg gatatgttcg atcagggaac cgtccctatc
    14521 tccaaaatcc tgccgcccct cgtagctgtc cggctcgccc tgaaagatac agtcaatgcg
    14581 gaacgcggtt ttgtcatagc ctgcctctgc cggatatgct gcatccagac gggcaaacag
    14641 cgcgtcggcc tcatgcaacg gcatttgctg gccgtccttt agctgggggc tttcgctcca
    14701 tagcacagtc acaagcggct cggctgccgg atcaagggcc ggggcctgtt cttcctcggc
    14761 ctgcgccggg gccgctgcct ccggggtaac gtcaaccgtg acggcctcct gttcctgccg
    14821 ggcctcgcgc tcctgctgaa gctgggcaaa atggccgtcg atctcggtta tcaattcgct
    14881 ggccgtggcc cggatggttt caagggaggc tttcagctcg gataactccc tgccgctgct
    14941 ccaatcggcc acatagccaa aagaatagtc cgacgtgtcc agcccgtaat actggcagac
    15001 ggtataggcc acgctttcgg cctgtacctc gcgggtgctg cggtctggcc gggccgcctg
    15061 ttcctcggcg ggggcctccc ggtcaatggc gtggagcttg gcatgggcaa tctcatggat
    15121 ggcggtcttt agggtctgca attcgctcat gccctcgttg atggcaatgc gctgttttgc
    15181 gtagaagcag cggcccttgg ccccgtctga aatcggctca atgcttatgg gatagggtga
    15241 tgtccgttcc agcgcggcaa agaaatcctg atactgctgc acgtcgccgg taagttcact
    15301 gatatagggc atgggaaaat ccttgccctc ggtctggctg atgtcaaaga ctgtcaccac
    15361 cttaaaggcc ggaaccgtca cttcctgttc ttcggtcacg ggcttgccgt ccgcgccgat
    15421 cacgggctgc tgggtggccg ggtcgatttt ctccatctgc tgcttaacct tgaacggggc
    15481 cggggccagt atcttaatgc ctttctcgcc ccgcttcaca tggcggtcaa attcatcctg
    15541 ccacctgtta tagcccgcca caatcgaacc gccctgcatg gcgatcagca gcgtattgtt
    15601 cagactgtaa tcgtgcatct tggacatagc ggataagtaa gccatatagc ggctactttc
    15661 aaaaagctcc tgtacgccgg tttccagacg gtcagtaatc actttcatgc gttctttgct
    15721 gttcatgccg tccagcatga tcgggataac cgggggcggc gctttgtcgg ggctttcgga
    15781 tgcctccggc tgctgggcct gcggttcctc ccggtcagct tccggctggg ggtagtgcat
    15841 cacccggtat tcctccggca ccggctggcc ctcatggacg cgctgccatt cgtcgccgct
    15901 tctcaccaga tagccgtact gggtaaaaac gccttgttcc tgctgggcaa tgtggcgtcc
    15961 aaactgcgcc gtatcaatcc cggctttcca ttcctccggc atatccacca tgccggaacg
    16021 gttcaggtag tagtcgccca actgtccatc ccccctaacg tcgggaagat gcacatagta
    16081 atccacattt tcggtgtagt cgatgatctg gccgatattc tcaaagccgc cacggggatt
    16141 ttgcagggcg gcgttcagct ctgcgatctc ggcggcgtca agctggccca gccgggcggc
    16201 aaggaaattc agctcgtcca cgtcggcggc cagcaccatg tcatagggaa tggcaaggtg
    16261 tctgtcctcc gggcaggaat acccgttgat aaaaaaatcc tgcggattgt cggcagtaat
    16321 gccaacatcc cgcagggcgg cttgcagcgt ttcggttgtg gtgggcaaat ccagccagac
    16381 gccttgtttg ccctgttcca aaaactgccg gttatggact tggatagaaa atacttcgtt
    16441 cacgcggtca ctcctttctc tgttctgttt caaaaaatag ggggttgggg acttccccaa
    16501 caagcaaaaa tccccggccc ggcagggacg cggccggggg attttaccgg gagtgtagcc
    16561 acactcccta tgcttgctgt gttactgtcc tttagctcct gtgttcaatg cggtagttga
    16621 cgtacttgcc cccggtatca gccaaaagca ccgtcccgtc gtaggttttg ccggtcttta
    16681 cggaatagag gccctttacc ttgactttgc cggttttgag cagcgcagcg gcgatcttcg
    16741 gggtgaacgc tttcttgcgt tcctcaaaaa atcggtcatt cttccacatg acgaactggc
    16801 aggcccggtt tccgcagtag tagtttttct tgccctcata gacagcctca ccacagcggg
    16861 gacacgtccc gataggaaca cgctcggcct gaaacaattt ctgcttttcc tcactgatac
    16921 aggaataggt ctgcaccagc tcccgcgcct gcgtctcgat gccgtccata aattcgtcag
    16981 gatcggcctg ccccttggcg atctcggtca gccggttttc ccattcggca gtaagctggg
    17041 gagaagtaag cgcctccggc agcaccacag ccagattgat gccgtccttg gtgggaatga
    17101 gctgcttgcc ttttctctgg acaaagccca tctgcaccag cttttccaga atggcggcgc
    17161 gggtggccgg tgtgcctaat cccttgcgct cggcatcctc cggcatatcc tcggccccgg
    17221 cccgttccat agcggacaaa agcgtatctt cggtgtaggg cttgggcggc gtggtgaaat
    17281 gctcggtgac agaggcggcc acgtctgcaa aggtctggcc ctcgcaaagc tccggcagct
    17341 cccgcaccgc ctcggcgtcc tcgtcggcgt cggtctttaa ggaagaacgg aaccggcgtt
    17401 caatctcttt ccagccgggg gaaaggacgg tcttgccctt ggcggtaaac tcctgcccgg
    17461 cacaggtaaa tgtggcggtg acggcctcat agatatgcgg cccggccacg gcacataaga
    17521 gcttgcagca gatcagggac agcagctttt tttcactctc ggccagagtg ccaaagccct
    17581 gcttcacaaa ttcagcggtg gggataatgg cgtggtggtc ggacaccttt ttgctgttca
    17641 ggatgcggtc aaactgcggg gaaaggttca ggcccttggc aaacggcacc agctcccaca
    17701 ggccggacac aaggctttcc acggcgggca gcatatcgtc ggtaagatat tgactatccg
    17761 ttctcggata ggtcagcagc ttctttagat acagtgcctg ggcatagtca agggtctgct
    17821 tggcggtata gccgaaaagc cggttagcct cccgctgcaa ggtggtaagg tcatagagct
    17881 tgggcggctg ttccgtcttt ttctcccgcg tcacggaaac gcaaacggcc tgcgcttttg
    17941 cacaagccgc cttgacggtg tttgcctcgg cagcgtcgga aaagcggctg cttaccgcgt
    18001 ccgcgccgcc cgccgtgata tggacgatgt gatatttctc tttcttgaaa tcggtaatct
    18061 tggcgtccct gtccaccagc atttttaagg tcggcgtctg gacgcggccc acagtcaggt
    18121 tcttgtggta caggacggaa aaaagccggg tggcgttaat gccgatcagc cagtcggcct
    18181 tggcccggca cagggccgat tgatacagcg gatcatagtc gccgcccggt ttcaggtggg
    18241 caaagccgtc cttaatagca ctgtcctcca tagaggaaat ccaaaggcgc tcaaagggct
    18301 tttggcatcc cgccatctgg tagacgaaac ggaaaatcaa ttccccctcg cgcccggcgt
    18361 cggtggcgca cacaaggccg gtcacgtcgg ggcgctgcat cagcgaacag agaacgtcaa
    18421 actgctgttt cttgtcgtcg gggacgatgt actgccatgt ttccgggaga atgggcaaat
    18481 cctcatagcg ccattttttg aaacgctcgt catagcgtcc ggcgtcggca aaggacacca
    18541 gatgtccgat gcaccagctc accagatagc cgttcccctc caaatagccg tcgtgtttct
    18601 ccgtggcccc gatcacgccc gcaatgctgc gggccacgct gggtttttcc gcgattacaa
    18661 gtttatatgt cattcctcgt cctcctgttc actcacaaaa tcagcttccg ggtcaaactc
    18721 ggtttcgggt tcctcgtcct ccaaatcctc gtcctcccca aaatcatact cgcccaaatc
    18781 gtcgctgccg gtggtttcag ccttgggctt tttgaacttg aaatagtaaa gggccgcacc
    18841 gccgcccgcc agcgccacca gcaggaacac gatcaggccg cccgcgccgc ccttgggttc
    18901 ttcctccggg gcttcgggtt cctccggctg gggttcctgc ggctccgggc cgctgcactc
    18961 ggtcaggttg gttttacata ccgggcaatt cgtgttcaca gccccggcct tgcatttcgt
    19021 ggtacaggag cagacagcag cgggggtgac ggtttccccg tcctccatca gcgtcagcag
    19081 atcggcttca tccacctgat ttaagaaatg gacagtttct tttccctcgt cgtcccggtc
    19141 aataatcaga taaaacacat tgccgttttt ggtttccacg gtgataaact gcttgccatt
    19201 tttcgcggcg ctgccgatgt cgtcaatcag tgacaggttc ccgtccgggg acagggcggc
    19261 gctggccccg ccgccattga acagttccag cagagaagca atttcctccg ggtcaatgga
    19321 gagggaaaaa ccgccctcgc cggtagccgc tacttccttt tcgctgacgg tcatatagtc
    19381 ggaatggaca tagccgatgc gctccggcaa gagaatttta atccagtcgc cgtctgtgcc
    19441 gactacctca accgtcgtcc cattgggaag ctgggtgaac gcggtcttgt caagccccgc
    19501 gccggtgcgg acattcagcc tgccgccgtt ggtggtgacg gtgccggtct gttcaggttc
    19561 ttttttgtcg gtgccggtgg tgatctggat gccgtcgtcc gtggcggcaa tgctcacctt
    19621 ggaaccgaac agcgcggaaa acaggtcggt gatgtccttg ccggtcagag ggccggtatc
    19681 tttttcggcc tcggtttctg tcccgtccgt ggcggtgccg gtttcgtctg tttcaggctc
    19741 caaaccgccc gtagcgggtt cggttgtagc ctccggcagc ggggccggtg ccgggtcatt
    19801 gccgcctgca agggcggtaa cgggaaaggc cgtgacgcag agcatcacgg ccagaagtgc
    19861 ggggagaata cgggaaatcc gtctggtctt attcttcatg ggcattgtcc tcctgttcat
    19921 ggtaaggggt tgcggcaggg gcggcctgca ttgcgccgct gcgtaagaac gcggcaaatt
    19981 cctccggctt catgttcatg ccgcgcacaa gctggatgat ctgcaaattc tcctgttcgg
    20041 ttttctgcgt ttccagctcc cgaagctgtt tctgaaactc cgcgatctta gacttggttt
    20101 tctggatgtc cttttcgatg cggtcaagtt tggttgccat aattgaaagc tcctttctgg
    20161 cgttaaggta aacgcccgta actgtaaaaa tgggattgcc agtagtttga agtaaggttc
    20221 gtgtaggaaa tcgggttccc gcaatgcagc atcacattgt tgcccacata caggccgacg
    20281 tgggacacgc cgggggtgtc gtaggttccc ttgaaaaata caaggtcgcc gggcttggcc
    20341 tgcgaactgg aaacaggggt gcagatgtta tataggccct gcgcccccag ccgtcccacg
    20401 ttccatccac tatgattgat tacccacgaa atgaagccgc tgcaatcaaa gctggtgctg
    20461 ggagagctgc cgccccacac atagggataa ccgatatatt tttccgcctc tttgagcatg
    20521 gcggcaaagg tggcatcctc caaagcctcc gggggtacgt cgtagtaggt cggcggcgtc
    20581 agggtggagg cgttggggta ctggctgccg gaaaacagat caggccggtt tcctagcgtg
    20641 gacatataca gggaatagaa acttagcgtt tcctcgtcca tgatatagac tggcacatgg
    20701 gacaggtcga agttttccag cgtgacgtag cagatgtaat agtcatacgg cacttggtag
    20761 gtgtctgtat gggtgttgcc ctccgcgtcc gtccatgtat cggtttcggt gcggtaacgg
    20821 gtttctacca cgacgttttc tgtcaggata tattgcttgt caaagagcat ggacaaatca
    20881 ccctgtacct ccccgatggt aaatatcccg tcatggagcg ccgacagaat ggaaatcagc
    20941 acataggggt catggctgat ctcgtcaagg tcaaaatggt attcgtcata gtcatgggtg
    21001 gcctcgtagt tgtccagata gtcttgcagc tcggcttcca gctccgcgta ggcgtcctcg
    21061 gcggccaaca tatcgctatc ctcggaaaag taagaggacg ccgtgatgcc gcttccggcg
    21121 ctgccgaaca tggcggtgca ggactgtaag ccgccgatga taagcagcat caaaagcccc
    21181 aacacaagga cggccagcgc ccctttccag tggcgggcca caaaggaggc cgcccgttca
    21241 ctttctttgg ctgcggcctt ggccgctttc gtggaggccc cggctgtctt ggccgcgccc
    21301 tgtgccgccg cgcctgcggt ctggcccgct gtccgggcgg ccttggcgta ctggcgcttg
    21361 atctgctgtt tctgccagaa ccgggaaatg gggttgctgg ccgcctgtgc gatctccggg
    21421 ttatcccgca aagatttctg gtagaaatac tccgcgttgg cagacaatag cctgcgctcg
    21481 gccttttccg cgtcccagta gggtttcagc ctgtggtgcc ggatggtgct gcggatggct
    21541 tttccggcct gccgctcggc aagttcctcc cccttatggc cgccctccac acccacgttt
    21601 tcatgctcga cttcatggat tttcccgtgg ccgaatagaa aaacctcgga aacaggacgg
    21661 cctgccggat tgggtttcag ggagggaggc cccttgtcct gtttgtcaaa gtgcaggacg
    21721 gtctttgctt tgccgcttgc ctcgtcaaag acggtttcct tgaccgggac gcgcttcttg
    21781 gggatggcgg cgcgggcctt atccagctta tcggcccgtt tgtccgattt tcggatatag
    21841 ggctgtaaat ccgggtcggc ccgttcttcc tccgacagtt ggagccgggc ggatggccgg
    21901 tgcagggcag cgtccccctc ggcggccaca gccccggcct gcttcgcggc tttcttggcc
    21961 ttatggccgt catggatggc gtcggcccgt tccagcagct tatcggcggt gccgcccggc
    22021 cccggcgcgg acaaatcctg ttcggcctcc cggctggaaa tgttctccac ctcgccggtg
    22081 gcctgatttt ccagcgtcag cccgtcgcgg gtcatggcct gcgtcacttt cgccttggct
    22141 ttcagctctt tcatggtggt tcacctcctt tgtggcgtcg ccgggtcata ctcccgccac
    22201 ctcgtttaag cgggtcgtca taatcttgta aagctgggtg ttgtgcggga tggggttggt
    22261 aaagggcagc accacgtttt caaagatcaa aaggccctcg ccgggttcgg aattgtcgat
    22321 gtacttctgc tgttcggtgg acaaattcaa gcgttccgca aggatttttc tatccccgga
    22381 cgcctgattg agcagcgtaa tgaagtcgct gttttcaagg atattttcaa tttccgggga
    22441 ggaaagcagg tctttgacgt tctgggtggc acctgttgga atgccgcccc atttcctaaa
    22501 ccgcttccaa atctccgcag aataggccgc cgtctgttcc tctttcaaaa gcaaatggaa
    22561 ctcgtcggca aaataccatg tggcctttcc ttggcttcgg ttggccgtga cgcgccccca
    22621 tatctggtct tggacaatga gcatccccag ctttttgagc tgcttgccca gctccttaat
    22681 gtcaaaggac acaagccggt tgccgatgtc cacgttggta cggtggttaa atacgttcag
    22741 ggagccggac acatacaggt caagggcctg cgccacccgg tcagcctccg ggacatgctg
    22801 atctaacaac gctttgtgga ggtcggacag gatcggcata ttctccgggc gggggtctgc
    22861 cagatagggc cggtagatca cgcgcacagc ccggtctatc acggtctttt caatggcttc
    22921 cagcccgttc ttgccgccca tgacaagctc acagaacgac agcacaaagt cggatttcag
    22981 ggccagcggg ttatcgtcct ccgaataatt caggttgatg tccagcgggt tcacaaagtc
    23041 cttgctggta ggcgacagcc ggattacctg tccgtggagc cgtttgacaa gggggtaata
    23101 ttcggcctcc gggtctgaaa taaaaatatc gtcaggcgtc gttaagaaca cactgacgat
    23161 ctcggattta cagctcatgg atttgccgct gccgggggtg ccgagcttca aggcattggg
    23221 gcaacgggcc tgcttcctgt ccagcataat catgttgcgg gacttggcgt tgatgccgta
    23281 atacatggcc gcgccgccct gaaaaagctc ctgcgtcaca aaggggacga acacggccac
    23341 gctggaagtc gtaaggctgc gctgtatctt gatctgattg acgcccagcg gcaggctgct
    23401 tgcaaggccc tgttcctgct ggtagtccag ccggacaagg ggacagttat gcttttgggc
    23461 cacgcctgcg gcttggaaca cgtcgttatt cagcttttgc ttggtgtcgg ccacgttgag
    23521 gacaaggaac gtcaactgga acagccgttc attgcgggtc tgcaactttg tcagcagctt
    23581 cttggcgtcc tcgccgtagg tggcaaggtc gctgggaaga atgtccatat cgtaaccgct
    23641 gcggacggcc tttttctgct ccgcaatctt catagcgtca aggtcggtaa ttttgcgctt
    23701 gatggtcttg atcgccttgg tctgttcaat ggcctgcaca tggagattga ctaaaacacc
    23761 gctttccgta ttgaggaagt cggccagcat atcgtccgac agctccgggg acaggatttg
    23821 caggaaactt accgcgccgt atttgccgcc catgccgaat gtctttgcat tgccgaagca
    23881 cagggaggac ggggcaataa aatccttggt ggagaggccg gacggggcca gccacttcca
    23941 gtcaaaattg aatatctcgc cgtccgggtg gtacacgcca tgcagcaggt tcagccgttc
    24001 ccagccgtcc atcacatggg ctacggcccc catgctcttg aaatagccta acaggtcaaa
    24061 gccgatgcgc ttcaatctgg ctcgcgccgc tttcacgctt tcggcctcga tggtgaatgt
    24121 caggtatttg gtctttacca tgccgttgtt gccgtttgca agctgctttt gcagaatgcc
    24181 ggtgtactcg gcccggatgt cgtcgaagtc gtccccctgc ggcgcgatct caaagctctt
    24241 ggcgtactgc accgggtcaa ctttccgatt gaggaaagaa aactggatat gaatggaggc
    24301 gtccacatag ttatacaggt cgcacagttt ttcaaagata gccgtctgcg tgtccggctg
    24361 ggcaagctga tagctgatgt ccgcaaactc aatgcacttg gaaaagacgc cgggcgatac
    24421 ccggcacacg ccgtccgggt acatgacctc gtaggggatg ctctgctgcg ccgtgtgggg
    24481 cctgccgtcg cccttatatt tacggattac cgcgtcaatt tcttttcgct gggcgcgggt
    24541 cagctttgtt ttttcggttt ctcttgggat ttcctttttg gacaatggcc tttacctcct
    24601 gttccatctg gtattgccgc acaagggcgg tgtaggtgtt gtcggtctga tagggacgct
    24661 cctttggctg gatgaagcag cactggatga tctgcataat caccacttca aggggctggc
    24721 cgtgacgctc gtacatggca agcaaaaagc ccggcagcat ggcaaatacc atgagcaggg
    24781 ccgccgcgct gttggtaaga tagtcacggg tgagaaaata taaggggacg ccgatcacca
    24841 gcgccccgga aaaacagatc agttgccgtt tggtaagccc aaacacaacc ttgcttttca
    24901 catgggttaa gtccttgggg acggttacat aagccatttg gcacctcctt tcacgtcagg
    24961 ataaggtcac attccacctc gttcccccac acgtcccagc cgggggtttt ctgtctggca
    25021 aacagctcca cgcggggcaa atcgcccgcc agctctacga ttttttcacg ggtcacatcc
    25081 ggctttttgc tgtgttgttc aatcgggctg ataataaact gatggacaga ggcagaacga
    25141 cgcttcggct tgccgtgtgt tgccagcagg cagatttccg cgtttcccct tgtccagcgg
    25201 cccagcccgt aaaaccatgt aaggctttta cggttctgtt tcagccatac aaaagccacg
    25261 gtcttgaatg aaaagcccca cgctttgatt aaccgcagag cttccggcag catggggaat
    25321 gtggcccaca aaaacagcag gcagtctttg gacgccagcc gttccaccgg cagggcgcac
    25381 agctcgtcaa tgctcatggt ggaatagtga ttttccgctg cgccctgtac gtttttgcag
    25441 tcataccgcc acggcgggtc agcgtaaatg atgttgtacg ttgaaataag caagttcctc
    25501 ctgtgtatgc ttggattttg ggatcaatgc gccccgaata cggcctttga tatactgccg
    25561 gtcttgaaca ggcagaagca cagcagcacc gtatagccca tacagcccca gattgcgccg
    25621 gatatgtcgg aagcggaacc gatattctgt atcagcaccg cgtagatacc caccacaacc
    25681 atgattaaaa aggcttggaa gcccagcgcc agcagggatt tcagataccc ttggcccatg
    25741 ccgcgccatt ccgcgttgcc cattgtggca agggggatag gccccagcga cgtgacaaca
    25801 tagatttcca ccatgcggcc ataggtcaca aggaaaatgc agatggaaag gatattcatg
    25861 gtgaggccca caacaagggt ttggaaccac agccccaaaa gagcgcccac gctcatagcc
    25921 tccaattggc tttcaaggtc tggtatcagg gtgttaaaat caatggatgt ctgcccgata
    25981 atcacaccgg cgctttgatt gacgacgctt tgggtggcgt cgaatacgcc catgacgatg
    26041 ttccatgtgt tcgttacgat caggattgca aacgcggatt tgaatatcca gcggaagaac
    26101 atggagctgt caaagtcgtg catattgttc ttttccgtta tcatctggat aagctcatag
    26161 cacatgacaa gggcgagtat ggccccggct atggggacga tcacggtttc cgacaggctg
    26221 tgcagcatat tgaaaatacc gctgttccat gcctgcgggg ttcgtcccac gtcggcggcg
    26281 atttctccga ctttggcatt taccgtatcg aacagcccgg acaggttgcc cgtgataccg
    26341 tccatgagga tgccttttat ccattcttca atgatttcac taatcacggg tagcacctcc
    26401 tttcccgcgc cctcccggtc tggccgggag gacgcggagg cgattagtta agggtttgga
    26461 cagggacaaa ggccaggatc agcccagcag cccggacagc aggggaacca gagtgacacc
    26521 gatcagggcc acgccgccgc cagcgacaag ctgcttgaca ccctgcgatt ttgcccccgg
    26581 attgtcctgc ccgtatccct ccaacagatt gatgccgccc catacgcaca gagcgccgcc
    26641 cagtccgatc acgatagtct gcaaagtagt aactgcggaa ttaaaaaatg ccataaattt
    26701 acctctttct gccggtttcc ggctcataat gattttttga ttttgttgtt ggaatgaaaa
    26761 aagccgctgt ttattcagcg gcggcgtcct cgtccgacag gtcgatttca tacaggtcga
    26821 atacttcatc ctgcgttacc acttgctgcc gtttccggcg cgtgatagtc aaaaatctgt
    26881 ccacgtcaaa ggtattcttc ttgtcggcgt cggcaaggta tttgtaccgg ggatgcttgg
    26941 taatatcgaa tttctccgat aaaaacgggc gcacaccccg tagctgcaag atacacttgc
    27001 cgccgtccat cacggcaatt tcgtcttggg acatcaactc ctttcctaat ttttgatagt
    27061 tcaatccgtg ggacgtttgg cttccccggt tctcgctggt gttgaaactg tcaatcgttt
    27121 ctttccccag cgcatcggaa atctccttgg catttttgcc gcgcccacta aggaaaagca
    27181 cactatcgca gttatccgaa atgatctcgg cggcgtcctt gtaaatcgct tttagctgcg
    27241 actggctctg caaaataata gaggccgata tttcacggct tcgaatggtg gcaatgagtt
    27301 tatcgaaatt gggtatttgg ccaatgttgg caaattcatc caaaatcagg cgtacatgga
    27361 caggcagccg cccgccgtac acatcatcag cccggtcaca aagcaggttg attagctggc
    27421 tttggagcat agccagaatg aaattaaagg tcgtgtccgt atcgctcata atgagataca
    27481 gcaccgtctt ttcgtccccg atggtgtcca gctccatttc gtcgtcctcc atcagctcgc
    27541 gtacctcccg gatgtcaaag ggcgcaagtc tggcaccgca tgaaatcagg atggaagaac
    27601 gggtcttgcc tgcggacagc aggaatttct tgtactggcg caccgcaaaa tggtcggggt
    27661 ctttctgctc caaacgctca aacatgagat cgacggggct ttgaaactcc gggtcgtcct
    27721 cgcgggcttc actggcgttt atcatttcca gcagcgttga gaagttcatt tcctccgctg
    27781 gggcctcgta ccagatatag ccgatcaggg ccgaataaaa caaccgttcc gacttcaccc
    27841 aaaaatcctc cgctgacttt tccccctcgc ccttggtgtt ggaaatcagg gtatttacca
    27901 gctttagcac gtccttttcc gaatggatgt agacaaaggg gttgtacttc atggacttgg
    27961 aaaagttaat ggtattcagg attttaatgc ggtagcccgc ctgctggaac atcctgccgg
    28021 tttccagaac caaagtgcct ttcggatctg tcaccacaaa cgaagtcgga tagtccgtgg
    28081 tcggaaagca ttgcatcagg ttgggtttca cgaaaaatct cgttttccct gaaccgctgc
    28141 caccgatcac cagcacgttt ttattccgcg ctgtcttggg gtctttgggc ctgccggtca
    28201 tggtaagccg ttccgtttgg gtgagcagga tattattttc aaacttgggg tcgatgtaag
    28261 gcgctatgtc tttggccgtc ccccagcggg cgctgccata ctccatgcct ttgcggtatt
    28321 tcttcacgtt cttgctcttg cagtacacca ccagccgcac gatcacggca ccggcgatac
    28381 cgatacacag gtcaaacagg tgcaggcttg gcagcgggtt ggcaaaagcc gccgcaaaac
    28441 catccgcaaa atgcaggagc ttccccgaca ggtcagcacc agcggccagc cggtacgcct
    28501 ccccgcattt cgcaaacagg tacacaaaaa tcagatacgg gaggttcagg atcagcaatt
    28561 tctttacgtc aggcttcaca gttccagccc cctttccttg attttctcct tggcccgctg
    28621 cttggtctgg gccgccgcct tttgcttcac agcggacaaa accttgcgga tagagggccg
    28681 ctgctccttg gaaagcgtct tggcggtaaa ctcccgaaac gccagatcaa ggttatctgc
    28741 atccttggcc ttgaaaatca caacgtagtg gggcggctgg gtggtcttat cttttcgtaa
    28801 ggtaaaatcc acgccgtatt tcttggcgca tggcttgaac gctccaatgt tggcctcggt
    28861 gatctcaatg ttggagagat cagccccatg ctttttaagc tgctttaggc tctgctggcc
    28921 gtggtgcagc gtgtttttgc ccttggcccg gtgttgcagg tactttttca gcgccgcttg
    28981 cagcacttga gccgtgagct tgcccgtttt catggacagg gcaatggtct tttgagtaac
    29041 ttcttcctgc aatcgcatcc ctccttgtca gaaagtcaaa agcggcgtct aaggcggaac
    29101 caccagacgc cgcaggtaga tataggtcaa atccgcaccc gcaggccgga aaggtcgtcg
    29161 gcccggatgc cgacaagata ccagttttcg gccatttcaa tgcgggtggg cctccatttg
    29221 ccgccgatca tcacgtcgaa acactccccg caatgcaggc cgccgtaata gtcggccaga
    29281 tcaaagcgga tgtcgtaacg gtctgttcgc tcgtcaaaaa tcaatgcgcc ctgcttcata
    29341 gggtcgtcct ccttttctcg ttacaggctt tcgccctcgc cgcaggaata gtccggcagg
    29401 ccggatttag gctttcccca atcgggctgt gccatgtcgt gcgcgacaag ggccgtgtag
    29461 tagttggaaa tggtgctggg ggcgttgaac agcatagccc gcaggtattg tttgatattg
    29521 cggactttcg ttgtgttctc ccgcagacag tcaaggacaa agcggatatg ttcgccggtc
    29581 agcttcatgt acttggattt caccagctcg gcagggtagt cgtccccggc gacacggatt
    29641 gtctttcggg cggtgcagac ggtttccagc atcaggtcta cgatttcgtc aagctgttca
    29701 cggtcaatgc tcctgtcctg aatgagatag gcatactcga tgttctccaa aatgatttcc
    29761 cgataaatcc gtacagcctc atcctttcct gtccttttcc gttccggcgg cgtagccgct
    29821 gcctcgccct ccataggggc aggggtcggg gatgggatag gaatggaatg ggtactttgt
    29881 ccatctgtaa ttattttttc tttttttgat aagtcagttc tttgtacttc tttatttaat
    29941 tgcgttggat tttccgacgc cggattatcc gatgtcggat tttccaacac cgggttatcc
    30001 gatgttggat tttccaatac cgggttttcc aataccggct gttcgtagat ggtatagacc
    30061 atatcggcca ttttgccttt tgcgtcacgg ccctgctcac gccggatata tccagctttt
    30121 tcaagctccc ataccgctgt cctgatcgcg tcgatgcttt cccggttgat ataggacagt
    30181 ccttttaggg tatagtccca atcctccggc aaggacaaca tctgcgacag caggcccttg
    30241 gcctttaagg tcaggttctt attccgcagg tggtgatttg acatcaccgt atagcctttg
    30301 ttcttttcca cacggaaaac tgccatagcg ttgttcgctc ctttcactgt gaatttgacc
    30361 gctgcatagt cggtcagctt gcccggctga tagggacact ctgcaaactg gcagaattga
    30421 tatttccaat ccgggcggta aaatcggcag gtgccgcaat cctccggcgc gtccgccccg
    30481 ccgccgtcgt agtgatcgaa accgggcttt tcctgcatca gccgttcaaa cgcccggtca
    30541 gggccggaag taaatagcat ggcgtcgcct cctttctcta tttgggcata aaaaagcggc
    30601 gtcctgttct cccatgacgg gaaagaggaa cgccgcgttt acggtgtcgt attcaattta
    30661 tgatgtgccg tatttggggt ggcgggtatt agcagtatgg ttcagcatat atgcggctca
    30721 atccgaaagt agtaaattgg tagtaaattg agttctcata tcctgcgaaa tgcccgtatt
    30781 tccggggctt tcagcgataa cctaaatttt tggaataaaa ctttcattat aggctactgc
    30841 aacatccatc caatcagcaa tctctttttg gatctcaggt cgtttccagt agccaacgac
    30901 gattttattt tgtttattta atcgagcatt gatgaaccca tattcgcggt caccatgagc
    30961 ggattgattt aaattcatga aatccatatc gatcgttttc caaggaatgc tttcgttata
    31021 ttgcgtagct aaatgaagca atggtttttg tagaagcttt gtcccgcgga tccacatttt
    31081 tgctggtgag aaagtatgca tccaagtgat cacacctgct acttcttctc gataattgac
    31141 ctctttcatg atttttgtga tcgtatcagc agtaactgct aattcttgaa ggcggattgg
    31201 ataaggcaat tggccatttt cattcagttc atcgaccatt tcttgtgcat gtttctttac
    31261 ttctcgcagt gcttcttccc catataaatg ctgtgatcct acaacaaacc aaaattcttt
    31321 ttctccaata ttcaacataa ttagccactc cttttatttg ttttgtccgt aatacgcatt
    31381 ttttccgtgt tttcgtaaat aatgtttatc taaaatccgt tgaggcagct cttctgaaaa
    31441 tgaattgagc tgtctggtaa ataaattcat cttgcatact tcatctagta cgactgcgtt
    31501 cattaccgca ctttgcgcat ctttccccca agtaaatgga ccgtgtccgt gtaaaagtac
    31561 ccctggaatt gctaagggat caattttgcg ttctttgaat gtttctatga taacttttcc
    31621 tgtttcatat tcgtacccgc tgtcgatttc ctgttgtgtc aaaaatcgag cacaaggtac
    31681 cgatccataa aaagtatctg catgcgtcgt ccccatcgca ggaacatcca atcctgcttg
    31741 tgcccagatc gtcgcccatg tcgagtgagt atggacgatt cctccgattt gaggaaatga
    31801 acgatataaa acagcatgag taggcgtatc cgaagaggga ttgagtttac cttcaatgat
    31861 atgattgtcc aagtccacaa cgaccatgtc gtctgctgtc atctcttcat aactgactcc
    31921 gctaggtttg ataacgaaat atcgtgtttc aggatcaaaa gcgctcacat ttccccatgt
    31981 atatttgacg agtccgtgtt taggcaagtc aagatttgct tggtatactt cttctttcag
    32041 ttgttccagc attttctatc actccttttt cttgcaattg atgaatcgct gttttttcaa
    32101 tgtcgatccc ctcacggtaa cgtctcataa atatctgata gcctgctatt tcttctgctg
    32161 aaggtgtgat ggtgattcct tggtcttgtc caaacacgtc ttctgccaag aagttttcta
    32221 aagacttccc atgtcgatcc atcatatagg ctgctaataa cgcgattccc cacgctccac
    32281 cttctccggc tgtgtccatc actgtaactg gtgcctccat agcagatgct agaatccgct
    32341 gtccaacttc tggtgtttta aaaatccccc catgccccac taaacgatca atttggacat
    32401 tctcagattt caatatatcc attccgattc tcattgcacc aaaagcactg gctaaatgga
    32461 tccgcatgaa attcgctaaa tcaaaacggc tacctggtgt acgtacaaat aatggccttc
    32521 cttcatttac tcctgtaatg ttttcaccgg aaaaataacc ataagaaagt aatcccccgc
    32581 aatccgtatc gccttctagc gctttgttga ataataccgt gaataattta tctctgctta
    32641 tctccatacc caaagaattg gtaaattctt caaaaatact gacccaagca ttgatatccg
    32701 aagagcagtt attcgtatga accatgccta ctagttctcc tgaaggtgta gtgaccatgt
    32761 cgatttccgg atggacattt tctagttctt tttctaatac gatcatagcg aaggcggaag
    32821 taccagccga aatgttccct gtccgtttgg ctacactgtt cgtagcgacc ataccggttc
    32881 ctgcatcccc ttctggcgga caaaccggga ttcctggtct caaatttccc gtagggtcga
    32941 tcagataagc ccctgattcg cttaacttgc cagcttcttc tcctgctact agaactttag
    33001 gcaaaatgtg atccaagtca atcgctacgt gcgctttttc gattaactga ccaaaaatat
    33061 ttttcatttc ttgatggtag gttttcgttg aaggatcgat aggaaacatg cctgatgcat
    33121 ctcctacgcc tagtactttc tcaccagtaa gctgccaatg gacataacct gcaagcgttg
    33181 tcaaaaaatt aatttctttc acatgttctt ctttattcaa aatagattga tacaaatgag
    33241 cgatactcca tctctgcgga atattgtatt gaaatttttc cgttaatatt cgttctgctt
    33301 cttcagtgat tgtatttcgc caagtacgaa atggtactag taactgttcc ttgctatcaa
    33361 atgctagata accgtgcatc attgcactga acccaatcga cccgattgtc gtaagattct
    33421 cgccatagat ttcgaatact tctgctgcca tttttcggta actgacgcgc agtcctttcc
    33481 aaatatcttc taatgaatag gtccagatac cattttctag tttgttttcc cactcataac
    33541 taccagcggc aataggagta aaagatgaat caatcaatac agctttgatc ctagttgatc
    33601 caaactcaat ccctaaagat gtacgaccat ctatgacatc taacatactt tgcgcattta
    33661 cttccttcat aatgatttaa ctccctcctt ctcgtcaaac ctgatcaaac cgtcttttta
    33721 gtagcgctta caatgattat tgtatacttt tgtacgtaca tgtcaagcgg ttatttacaa
    33781 gaatacaata aaaaacactt gttttgtacg tacataagtt ataaaatgaa attgcttaca
    33841 aaatctgatc aaccgccttc tcgaaattct agaaggagag aatacttatg aaaaaagaaa
    33901 aaaaagtttc ctcatcgttt atttattttt ttggcgcatt tggcggcatt ctatttggat
    33961 atgatattgg tgttatgacc ggcgccttac cttttttaca gcatgattgg ggtttggcag
    34021 gtaaagcttc tttgatagga tggatcacgt cttcggtcat gttaggtgcg atccttggcg
    34081 gctctttatc tggtcttctt tctgataagc ttggacgacg aaaaatgatt cttctttctg
    34141 cacttatttt tatggctggt tctgtccttt ctgcatctgc ccctcacaat ggttcttatt
    34201 ttctgattgc agcaaggatt cttctaggtt tagctgttgg cgctgcatct gccctagttc
    34261 ctgcttatat gtctgaaatg gctcctgcta gactaagggg aagattgtca gggatcaatc
    34321 aagtgatgat tgcttctggc atgctccttt cctatgttgc agattatttg ctaaaagtgt
    34381 tgcctgaaac gatggcttgg cgcgtgatgt tagggctcgc tgctgtcccc gcgctgattt
    34441 tatttttcgg tgttttagct ctaccagagt caccgcgttt tcttatgcaa tctggccgct
    34501 tggaagaggc aaaaagagta ttgaactata ttcggacacc aaaagaagct gaacaggaat
    34561 tcgaacaaat ccagctgaat gtcaaacaag aaaagacaac cggaacttct tggcatactt
    34621 tgtttttaga aaaatatcgt tccttagtca ttgccggtat tggtgtagca gtattccagc
    34681 aatttcaagg agctaatgct attttttact atattccgct gatcgtagaa aaagcgactg
    34741 ggcatgcagc gagcgatgca ttgatgtggc cgatcatcca aggaatcatt ttagttgctg
    34801 gttctttgct ctttttggtt attgcagaca agttcaatcg gcgaacttta ttgaaaatag
    34861 gcggtagcgt gatgggactt tcattcatcc taccagctgt tttaggaact gtactggatg
    34921 ctcatacaaa ttcgttgttg attctcttgt ttttatgtat ttatgtcgca ttttattctt
    34981 gcacatgggc tccactgaca tgggtaatca taggcgaaat attcccacta gctgtccgcg
    35041 ggcgagcatc tggcctagcc tcttctttta attggattgg ttctttccta gttggcttgc
    35101 tttttcctgt gatgactgct tctatgtctc aagaaatcgt tttcggcatt tttgggatca
    35161 tctgcttttt aggggtttta tttattcaag agatcgtacc agaaactcgt gggaaatctt
    35221 tagaggaaat cgaacaaagt gcatctaaaa aaacttatcc taaacgtatt tctatccatc
    35281 attcttaaag aggttgtgac agaagtggtc agcttcaaga aataagaagg aaccgcttag
    35341 tttccagtca caaggaacaa tttcaaaaaa cagcttctca tgtttgatga atattgtgac
    35401 ttgtgaccag ttggtaggag aacaccgttt agtggagagg tggtgaaaga aacgttcagc
    35461 cttgagcgat gacaaaagct ctcacaaaca ttgcgacgag taaccgtagg agcaataaga
    35521 ggcggtaaaa acccgtctct tatttttcgt tttctttcac tgtttcccgt tcaactagta
    35581 caggttcata gagaatattt ggctgtgcct gtcctttttc aatcgttgtg acgatccacc
    35641 gtgcggcatc ttgtcccaac ttttcttttg gatgcgtcaa tgttgtcaat tttttattcc
    35701 ctaaatggct taaagaagaa tcgtctgttc ctacgatcga taggtcatct ggaatatgat
    35761 agccattttc tgtcaactta tctagcatta aactagctat ttgatcgtta tagcaaatga
    35821 tgccatctaa agcttgttct tctttcaacc gttgtactgt tttttcagcg attgtttctc
    35881 gtgtttccgt ggtgaaagta atgatatctt ccgtcaaaaa acgcacatta tactgttcac
    35941 acgcgctgat aaaacctttc atcctgtatt ttccttgaag atcgtcgatt tttgtgatga
    36001 acaacagacg ctgatgtcct ttttttatca aatattctgc tgccataaaa ccgactttca
    36061 catcatctaa acaaatataa gaggcattta actcttcata agcagcattg atcatcacca
    36121 tcggaatgcc ttgttctctc aaagcaacat aaagtgctaa gtttgggtta tactgattac
    36181 ttttcgtagg ctcaacgatc aaaccatcta ccccataagc aatcattttc ttcaaacact
    36241 ctttctccaa ttcgtgatcg ttattcgtac tggctaaaag caatgaatac ccagattctc
    36301 gtaattcatt ttcgattcct cggataatcg acggaaaaat ataatcagag agatatgtgg
    36361 tgatgacacc gatcgttttt gttctgttca atggtgtttt ttctttctta tagctgtcat
    36421 ctacatatgt gcccgaccct ttttctttac gcagatagcc ctcatttacc aacacagcga
    36481 ttgcttgccg aatcgtatgt ctgctgacgt catatatttc ttgcagcttg aattctgagg
    36541 gaatggttgt atttacttcg tattcctcac gaaggatctt ttgttttatc tcttctgcaa
    36601 tatcttgata ttttgccatt tgccttgccc ctttttattt gtacgtacat atatcataac
    36661 gagtctgcaa ggtttattca agcaaaaatc aaggtttctt gtgctcataa ggcatacgga
    36721 acaggttcac caaattctgg aaatccttgc tcattccacg taaagcattg cgcgttcgcg
    36781 tgccgattag gattgtctaa cggatcccct ttttggttct tctctggtcg agcatgatag
    36841 atcaaaatat caaagcaccc gtcttctgaa accgtaaacg agttgtgacc aggaccaaat
    36901 tgcttatttt tttcagaaga aacgaatact ggctccgata atttatgcca tgattctttt
    36961 aataaaagat tcttgtgctc atcagcccac agcaggccca tggcatagtt ttcatctgtt
    37021 gcactaccag aatacgtaat gaatattttc ccattgcgag taaggactgc tggaccttca
    37081 tttactgaaa aaccccgttt ttcccattca tactcaggta tagaaaggag gatctgcttc
    37141 ccctttaacg tccaaggatt atccatttcg gatagataaa gattagaatt cccagtaatt
    37201 tcaggatctt gttgggccca cacataatat agctttcctt gagaagagaa agttgttccg
    37261 tctaaactga aagtttccct tttcgttttt atttgtccct tttctatcca atctgtattc
    37321 attggatcta tatgctgatt ttcaagtacg aacatgcggt gatgatgaga ttcatcacgt
    37381 atagttttat gattgcttgc agcaaagtaa atataccatt ttccattgat ataatggact
    37441 tcaggtgccc agatcaattc actcatcggt ccttcttcat gagcctgcca tacaatcagg
    37501 cttgcagcat gttctaattc attcagtgac tttgcccttc ttaattcaat cacttggtag
    37561 cctggaaccg atcctgtaaa ataataataa ccatctgtat gtttatatac ccaaggatct
    37621 gcccgttgcc gaacgatagg attattataa agtgtcttca tcataacaaa tttcctcaca
    37681 ttttctttat tctaattaca ttccaagagt atttttctat ccctacattt aattcgtcat
    37741 gtttttctat tgaaaaatag tttatttcag gttttatttt ttctggttct tcacgtgtat
    37801 ttttgtccaa cagatcgcta ctggttaatg tgtagtgctc tccttgatct agcaaattga
    37861 aatcatgttc aatcgttatc ttttgttgtt catttgtgcg attgatcaag aaaatagtca
    37921 gctgattgcc gttatctacg atcacactgt ccacataagg aacatttttt atcttttcac
    37981 aatcataaac agggcaaatg atttgttgtt tcaatacttg acctttagca tatttcgata
    38041 agtgttgcat cacataataa gttggattcc tccatgcttg tcctttagca tctgtcagta
    38101 ttaaaggtat tgtgtttact aacaatgatt gacaactaat ctttacgcga tctgcgtgtc
    38161 gtaaaatagc cagccctaat gaaccaaata ataatgtatc ttccatagta aagtaacacc
    38221 aatcgatggg actaccgact tcaaaatccc tatgtctttt ttccggttgg gcatgtacat
    38281 tccattcatc aaacgctaga tacattgttt tctcacttct caaatatcct tttacataat
    38341 cacaagtagc aacgatttct tcaatttgac gatcgaatcg ataagctttt gcaaggtatg
    38401 tcgctgtatc atcacgctca tttttaggag gtttagtcaa gtcttcttca tcatacttat
    38461 caatatagtt atgcaaagct aaataatcta cattctcata agcttcttct aatgcgatac
    38521 gatcccattc agggtacgat ggtaaacgtg gcgtagagct tccaactaag attgtttcaa
    38581 ttgaatcatc cactaacttc atgacttttg aggcttcatt tgctaaccta ccatattcat
    38641 aagcactctt agcccccact tgccatggac cgtctagctc attccctaaa caccataatt
    38701 taacgccaaa aggctttttt tgcccatttt ttattcttaa atcactccag aaggttcctt
    38761 ttggaaaatt acaatattct actaaatttt ttgcttcatc aattcctttt gttcctaaat
    38821 tcaccgtgaa tatcggtttc gcttgtacat gactgatcca tttaaaaaat tcgtggagtc
    38881 caaaagaatt tggttctata cctcgccatg ctaaatcaat tttttttggt cgttgttctt
    38941 tcctacctac agtatccacc caatcataac cagatgtaaa gtttcctcca ggatagcgaa
    39001 tgacacctaa ttctaattcc tttacataag agaggacatc ttgtctaaac ccgtcaccat
    39061 cagctgtttc atggcccggt tcataaatcc ctgtatagac gacacttccc atatgctcaa
    39121 caaatgagcc aaacagccga gaactgatct ctcctaccgt aaaatcctct ctgattttta
    39181 ctttcacttc ttcgtccaac agctttccct acctttcatt tcctatagtc aagataatag
    39241 atacaagttt ccatacgcca ccagcaaaga taaaaataaa aggagggaaa agaaatatga
    39301 gcagtacaaa tcctaataac aatacgcaac aaagaatatt tctcaaaaaa tcaaaaaata
    39361 ctttccatgc actttgttca aaaatttgta aaaatgtgat atctttgttt tcagaaatca
    39421 catatatcca ggataaaaga aacatggaat aaataagtaa aactacatat ccactaattg
    39481 aaagtacgat tgtctgttct tctaataatt gattaacaag aaaataaata atgatcgtta
    39541 acagactaag gaacaagttc ttaccaaaat gttgctttat tccttgaaag aaaaaataaa
    39601 tgatatttcc tgatccctca cctttccatt gcgccattac ataaaaaaca gcacatgtag
    39661 caggcacgat agtaataaca ggcaaacaca cgattaccca gagaatacct aataagatgt
    39721 aatcagaaac cacaatcaac tgtccataaa atttagtctc aactattttc atcttcctca
    39781 ctctttcatt ccagacatag ctgttccttg aacaaaatat ttctgtgcaa aaatataaac
    39841 cactagtaat ggcagcattg aaataaccgt tccagccatt acaggtccat aaaaagaaat
    39901 gttctgccct gtaaataaag ctaaccctgc tggtaaagtt ctcatttttg aactacttgt
    39961 caatatcaat ggataaagca agtcattcca actattcatc agcgtgaaaa tccctaatga
    40021 taaaagagta ggtttgctca atggcaacat gattttcaaa aaaatattaa actcacttaa
    40081 tccatcaatg cgtgctgcct cttccaaaga atctggtaaa gtaataaaaa aggaacgcat
    40141 catgaagata ccaaatgcag ttgtcatacg aggaatgatc aaacctgcat aagtatcaag
    40201 catgccaagc aaattgactt caataaatag aggaatcatg aagacttgga atgggatcat
    40261 cattgtcagc aaaacgaaat agaacaaaac tgattttcct ttgaaacgca tacgagcaaa
    40321 tgcatacccc gcaagagaat caaagaatac agaagtgatc actgtccctc cagcaaaaat
    40381 cactgtattt ttgatgtaat ctaataaagg gatcgttgtc caaaccttaa tatagttatc
    40441 tagggtatag ctatctgcaa atattctagg cggaaatgag ataatgtctt tttcgtgttt
    40501 aaaagaagaa ataatcagcc acaaaaaagg aaacgcaata accaacaata taactagcat
    40561 actaatcgtt cgaatgattt ttttaccact aactgctttt cgactattca cagtaactgt
    40621 aatcgagctt tctggtgcca tacaggtttc cctcctattt catttgtttt tctttccgtg
    40681 acatgtacac attagtggag atagctatag ttgcaacaat gataaacaaa accgaagaca
    40741 gtgctgatgc atagcccaat tcataaggtg ctgtaaatcc tcgactgtaa atatattgaa
    40801 cagctgtttc tgtcttaaat tgtgggccac cagcggttgc aacatatact tggtcaaaca
    40861 cttgcatcga accaatcaga ttcgttaaaa tacaaaaacc taaggaggga acgatctgag
    40921 gtagcgtaat gttaaaaaac tgctgtcgat ttgttgcacc atccatttga gcagattcat
    40981 acaaagaggg agagattccc tgaatagcag tcaagagaat cgtcatagta acaccaaaat
    41041 tcttccaaac agtcatgatg gctaccgtcg gcatagcaag ggttggatcg cgaaaaaatt
    41101 gagggatcgg caagccgact tgtgaaaaca agtaaggaat cgcccctaca ttcggatcaa
    41161 gcaacataga aaaaataatc gcaattgacg tcaatgaaca aataactgga atgtaaaatg
    41221 tcgaacgaca aaaacgattg aatctggtat ttttagataa tgctactgct gctaataaac
    41281 caacgataat ttgtgttggc gtttcgagta cggtgaaata taaagaatga atcaacgaat
    41341 taactgctcg ttcatcacta aatatacgtg tgaaattttc aaaacttaca aaatttcttg
    41401 atgtaaagaa aatattcaaa tctgtaaaac taatagcaaa tgttcctaaa agcggtatga
    41461 cagtaaataa taataaaact aaaaaagatg gagttaaaaa caaatacgca gcacgatcag
    41521 gacgattcca atatttggtg aatccgttca tatagtccac ctcatctttc attttgataa
    41581 aatatacaat cttggtttaa acgaatctga ataagatatc cgaacaatcg ctgtgatttt
    41641 tgcaataaca cctatctgca aatactaggt cgatcattca gatatctgta tcttgccaac
    41701 agtctatcct gtataaagtt ctgtactatt tttgcagtaa ttgattgatg gcatcatctg
    41761 catcgttcat gagtgtctca ggatcttctc ctgctaataa tttttcaatc agtggattga
    41821 tgatatcgtt attgatcgca gagatttggg taaaacctgg taaatatggc tctgcatagt
    41881 ccatttgttt cgataattca gatacaatag gatcattttt tacttcttca tcttttgcta
    41941 ctgaatccaa gtaggcagga aaaccatttt cgatactcca ttttttacca atttcagttg
    42001 tattccaata tttcaaaaac tcatagacag cttctttttt attattatct gtacttgccg
    42061 gaatggcata tcctacgcca tctaaaatag ctgttttttt gtctgaatca ctcccttgtg
    42121 gtaaggtagt cacattataa tcaatctcgt ttgctttcaa tccgttattt aaccatggcc
    42181 cattgatttc aatggctagt tgaccagcat tcattaaatt gtccatttcg gcgccagaaa
    42241 tcgattctgg accagtcttg tctacatgga tcattttttg gatcgctttt aacgttttaa
    42301 ggttctcagg agacgcaaat tcagacttag tataatcatc gttcactaat ttaccgccat
    42361 ttgctaacat ccagttatat aacggtgcag ttccatcctt attgaagaca aaacctgata
    42421 catttttact actatcagtt aattttggtg ccatttctgt caattcttcc caagtagtag
    42481 gtggttgttc agtatctaat ccagcttgtt taaacaaatc attattccaa tacatataca
    42541 tgccttgtac ctgcatgggg acaaaatact gtttaccttc tacttcacct aattcaatag
    42601 ccgtttcttt aaaatcagat ttatctactc catcatattc ccagaaatcg tctaatggtt
    42661 gtaccgctcc gttttctaca tactgtgcaa aatctggata atttaatgca ataaagtcag
    42721 gtgctttttt agaagaaatc gctgtaggaa gtttttcatt caaattggcc caagtcatga
    42781 tatccatttc aattttgatg tttttatcat ttgttttatt aaattcatta acgatttctt
    42841 gcaatatttc accatcagat gcagtaaacc cattccaaaa agtcaaagtc acttctttat
    42901 cagaatcaga ttctgctgaa cttccgccac cgcaagctcc taaaatacct gttgcagcta
    42961 ccaacaaaga gccaattaac cattttttac ctttcatttt ttgttcctcc ttcatctgat
    43021 aaacgacatc tgaccacatt ccaagatagc ggtttcaata aacaattgat tttcccatct
    43081 tcagctttta catttgttga atgacttggt tttacttgtt cacttttagg aagattagtt
    43141 gcttttgtat caaatccact catttcagaa aaatcaatca ctccctctaa tgataattca
    43201 gacaagtgaa cagttagatt catttcttct tctccacggt taactgcaaa tatgacaagt
    43261 tctttgtcat ttattacggc tatactttct aaatacggca cttcttcaaa atcttccgtc
    43321 gcatagtttg ctgaacgaat ttgtgggctt aacacctctc cttgtccata cacagcagct
    43381 tgcataaatg gataatagat cgtctgtctc caagcttctc cgtttgtttc tgtcctgatt
    43441 ggtgcaataa cgtttaccaa ttgagcaaga caagcaatct ttactctatc tgcatgtttc
    43501 aataaagtga ttaatagaca gcctaatagt aatgcatctt caaaattata gttatcttct
    43561 agtaaaggag gagcaatctg ccaaggcgct gcttgctcat cttgttccgc tgaatgatac
    43621 caaatattcc attcatcaaa ggacaggttg atctgcttct tactatgttt cttcgccttg
    43681 actgtatcgc acatcgctgt cacttcagaa atgaaccgat ccatgtctaa ggaacgtgca
    43741 agataatgag aaagatcatt tttttggttg ccataatatt gatgcagaga caaataatct
    43801 atttgatcgt acgcttgatc aagaactgtt aactcccaat caccaaatgt aggcatttgc
    43861 cgattcgaac ttccgcataa aaccacctca attgaatcat ctacgagttt catcgcctta
    43921 gccgtttcct ctgctaaccg tccatattct tccgctgttt tatgtccaat ctgccaagga
    43981 ccgtccattt cattccctaa acaccatgtc ttaattccaa aagggctctc ttgaccattc
    44041 gaacgcctta aatcactcca ataagttcct ttaggaaaat tacaatattc gactaaatta
    44101 cgagctgcat ctactccacg agtacccaga ttgacagcca tattgatttc ggcccccaca
    44161 tgctgacacc agttataaaa ttcatgaatc ccaacttcat tcgtttcaat tgtccgccaa
    44221 gctaaatcca accttctagg tctatttgct atgggcccaa tactgtcttc ccaacgaaat
    44281 cctgacacaa aatttccacc aggatatcta atcatgggaa tgttcaattc ttttaccaag
    44341 tgaatgacgt cttggcgaaa tccactttta ttagctgatg gatgatctgg ctgataaatc
    44401 ccttcatata ctgctcgtcc catatgttca ataaatgaac tgtacaaccg cggatcaact
    44461 ttgcctacac gcttgacact actaatcaac attgtggctt ccataactga cctcctttaa
    44521 tttatacatg aataatacac ctcgttgaaa gcgttgtcaa taatataaat gttaaactta
    44581 cttatttttt atcgatttta attaaccaaa atattaataa tgattaaaac aaataattta
    44641 atataacttt tattaacaaa tatgttaata tataagaaaa accttttaag aggtgatata
    44701 tatgcaacta caaataaacg aagaatcctt accggtatat gaagcattag ctagtaaaac
    44761 aaggatcaag atcatccagc tactttccaa aaaaaagatg aatgtcaaag atttggcaaa
    44821 agaacttgga gtgagcagtg ctatcacgac gatgcacgtg aaaaagctag aggaagcaaa
    44881 catcatcaaa acagaaaaag taggacaaca aaaaatttcg agccttcgtg tcgataaaat
    44941 cgatattagt tttccagaaa aaatattcaa tgcttttgat acgaaagaaa catcgatacc
    45001 tattggtcac tatacaaatt atgcaattga accaacatgc ggtttagcta cgatccatga
    45061 ttttatcggg aaagtggatg aaccacgcta ttttatggat cctcgaagga tggatgcccg
    45121 cattctctgg tttaccagcg gatttgtcga gtatcaggca cctaattttt taaatacaga
    45181 ggatacattg gagatgttgg aagtttctgt ggaaatttct tctgaatttc ctttttcaaa
    45241 tgacaattgg ccttcagata tcactttcag cctaaatggt gtggagctag gaacatggac
    45301 gagccctgga gattttgctg atatccgcgg taaatatacg cctgattggt atccagataa
    45361 tcttaatcaa tacggcttgc tgaagacgat ccgaattacc aaacacttga cgaatatgaa
    45421 tggagaaccc ttgtcaaaca tcacgatcaa cgacatccct aaagagcaag acacttggca
    45481 tttgcgaatc gaagtgaaag acgatgccaa acatgtgggg ggctgtactt tatttggtaa
    45541 aggattcggt aattacgatc aggatatcaa attaaaagtt tactacagct gatatttttc
    45601 ttttctattt tataaaacaa aaacagccaa tccctatgaa gggacggctg tttttgcttt
    45661 attgttattt ccagaaatca tccaaaacgg aaattggcaa atgtcgttta tgttgtgtct
    45721 tgttccacca tgcttcgatt ttttcttgtg cttgagcggg aacttctttt ccttctagat
    45781 aatcatcaat ttcattatat gtgacaccta gtgcgacttc atctgcaatc attggtttcc
    45841 catcttcaag atctgcagtc ggaatttttg tgtataattt ttccggtgca ttcaatgctt
    45901 gaagcaattg tttcccttgt cgtttgtcca aacggaataa tggcaaaatg tcggctccac
    45961 catcaccaaa tttcgtgaag aatccagtaa tgttttctgc agcatgatct gtccctaata
    46021 cggctcctgc tctttctcca gctacggcat attgcgtaat catacgttga cgtgctttga
    46081 tatttccttt gttaaaatcg ctgattccca cacctgcttc gcttaatact tgtacttgtg
    46141 catcaacagc tggtttgata tttactcgca gactaacatc gggctggata aagtcaagag
    46201 cagcttttgc atcttcttca tctgcttgtt caccataagg aagacgaaca gcgataaatt
    46261 gatagttttc atcttttgtt tcttcacgca tttcttccat cgttagttgc gccaaacggc
    46321 ctgctaaagt agaatcttgg ccgccgctga tacctagtac aaaagtttta agaaacggat
    46381 attttttcaa atatgctttc ataaagtcaa tacttttacg tatttcttct tttggatcaa
    46441 ttgttggttt gacacctaat tcattgataa tttctgtctg caggctcatt tattctcctc
    46501 ctatgcttct gtatgaagtt ctgctacgct ttttttcatt cgttccatga tagccatttt
    46561 atggttccag cattcagtag acagatcgac tgggtatttt tgcggattca agtctcgttt
    46621 atactcttcc catagtgaat ctagattttc ttttgtatat tctttgattt cgtttagtgc
    46681 aggtaattcg taaactcttt ttccttcgat aaagatatct tgtaaaactg ggcgagctgt
    46741 aaagtctcga acagttttat tgataaacgt atgcactgga tggaacatga agatagcttc
    46801 ttcttctcga gggtcttcat cccataatgt cacgtagtct ccttcagatt tcccatcaaa
    46861 atttcgagtg atgcgccaca cttgtttttt ccctggagta gttacttttt ctgcattgct
    46921 tgataacttg atcgtatcca tcatttttcc ttcatcatct tcgatcgata ctagcttgaa
    46981 tactgcacca agggctggct gatcataggc tgtgatcaat tttgtcccaa caccccatac
    47041 atcaatttta gctttttgca tctttaaatt caaaatcgtt gcttcatcca agtcattcga
    47101 agcatagatt tttgcttccg taaatccggc tgcatctaat tgttcccgaa cacgcttaga
    47161 tatataggcc atatctccac tgtcgatgcg tacgccttgg aagttgattt tgtcacctaa
    47221 ttctttcgcc acgcgaatcg cacttggcac acctgatttc aacgtatcat aagtgtcgac
    47281 taagaacacg cagtctttat gggttttagc gtaggccata aatgcttcat aatcatttcc
    47341 ataagattgg actaacgaat gagcatgggt cccgctagct ggtatcccaa atatcttccc
    47401 agcacgtaca ttgcttgttg catctgctcc gccgatatat gccgctctag ttccccagac
    47461 tgctgcatcc agttcttgtg cccgtctagt tccaaattcc aatagtggat cttctccgat
    47521 gacagatttg atacgagctg cttttgtcgc gatcaacgtt tggaaattga ccatattcaa
    47581 cagtgctgtt tctactaatt ggcagtgcgc taaaggccct tccacttgga tcaatggttc
    47641 atttgcaaaa actagttctc cttcacgagc agaacgaact gttgctttaa attcaaaatt
    47701 ttgtaaatac tccaaaaaac cttcaggata gacttctaat ccacgcaagt aagcaatatc
    47761 ggaatcattg aacgtcagat tctctaaata attgactaac cgttccaatc ctgcaaaaac
    47821 cgcgtatccg tggttaaaag gcatttctcg aaagtaacat tcaaaaacag catgtaaatc
    47881 agctcgacct aattcccagt atgtctgcat catattgatt tgatatagat ccgtatgcag
    47941 cgtcaaactg tcgtctgggt aagtattatt catcttgtat tactcctctt ggcaagtttt
    48001 catttcctac ccattataac aaaaaaaatt aataggaaaa gaaatcttcc attttttctg
    48061 aaaaagcaca tgttttacgg atatttcttg ctaaaaatga actccatctg ctaaaactat
    48121 cctttcttat tggtatttaa cctaaacgag aaagaatact tattttattc aatgtatccg
    48181 agacacgaag aaattagcgt tttctatttt tcttacttga taaaataagt agattttcct
    48241 actacaatcg tagccgttaa gataccgatg attgaacaaa tataaccaaa tgtctctaca
    48301 acataatcaa tggcaaaagt ttttgaagca ataatacgtc tttccttttt tgcttcttat
    48361 ccccaaagaa acggatataa cttattatgt attgaatttt tttggaaagg cgaattatga
    48421 caagatatac cttgcgttga aaaaactcgc ggaaaaaata tcacacgttt ttaaaaagat
    48481 acaaagtaag aaagcagctg tcaatagaat ggaaacaaaa atggcgagac atcaatcagt
    48541 ctcgccttgt tttttattgt atacattaga tatggagcag gttaccataa agatgattat
    48601 tagtcgttat taaatagaat ccttcgtatt tttttgttct atcactacaa tatctttatt
    48661 tggacgtttg aattgtattc cggcacgttc tagctcctgt ttcactccta catggacttt
    48721 gacatcttct cgtgtcattt ttaaaacgtg atgaatcgca tagtcgattt cttgccttgt
    48781 gatttttttc ttcgtattga tcatcacgac ttgcttttta tcatatgtgt ctaccaatag
    48841 cagttgtgtt cgatctaacg aaaataattt gtaataatta atagccgtat tcccaaaaaa
    48901 gaattccact actttaggat aaaatgtctt aatatttaaa ttactattca caggtgtttc
    48961 gattagcttc atctcattcc tcttttctat atagtcgatt tagatccaat cttaagttat
    49021 gttaccatct ttcctagcat taaggaatcg gttacaattg aacctttaaa gacaaaagga
    49081 tttacctttt atcacttaat agtataacat aatttcatga gaaaaaaata caattttttc
    49141 ttgaccatct cgttacgtaa aggattatgc ttacatttgt caggaggaaa aataatggag
    49201 tacacaataa agaaaatgtc agagatatca ggagtcagtc cgagaacctt gcgcttttat
    49261 gatgagattg gactgctaaa accagctagg atcaattctt caggttatcg gatttatggc
    49321 aaaaaagaag tcgatcgtct gcaacacatc ttattttatc gaacaatggc attcaagttg
    49381 gatgatatcc aagaggtctt agacaatcca tcttttgacc accagaaagc tttaatcaag
    49441 catcagcaaa tgttgctgga aaaacgggca caaatcgata ccctcttgac aactgtccaa
    49501 cagacacttg atatgtacga aggaggaaga aaaatgagtg acaaagaaaa atttgaaggg
    49561 tttaaacaac aaaagttgaa agaaaatgaa gaatcctatg gacaagagat tcgacaaaaa
    49621 tacggaaaaa aaaaggttac agcatccaat gaaaaatgga tgaatatgga taaagaaacg
    49681 tatgaagaaa tgcaaactgt tgaaaagcag atgttatttg atctcactct ttacttaaaa
    49741 gaaccagaag atgaaagctt agcagaccgt atcttccaag ctcataagaa gtggttatct
    49801 tacagctggc ctgaatatca gccaaaagcg cataaaggac taggaatgat gtacgaagcc
    49861 gatgaacggt tcactgcata ttatgacgag cgaagtggtc atggtgcagc aaaagcttta
    49921 aatgaaatta tccaaaaaaa ggcgtaatct tttacatgat ccaacaaaaa agtacacgta
    49981 aaatgaccta ataacaaaac agcagacacc caagttagat ttttatgcta acttttggtg
    50041 tctgctccat tctttcacaa gttttttcat cctactttaa atatattcat cgttgaataa
    50101 acgtataagg tattttcact ttatcctttt tttctgtaag aaacaattga aatgccattt
    50161 ctccgcaagc ttccagatgg tggtcgatgg ttgggaaacc aagaagctcg ctgatcagca
    50221 aattatcgcg tccaatcacc actggtgtct tatcttgcag atagctttgc aagatgcctg
    50281 ctgcaaccat atccgaattt gtaaagacac catcaactcc aagctcttta aaaaagaagc
    50341 ctgcttgttt tcctttctct gcatctatac aatcccaaaa aacaagtgat tcatcaaaag
    50401 atggaaaaag ttgatgacat agctgcaaag tgatttttga gttataactt agcctgccac
    50461 ttcgccccaa cgtgatgccc aattgcttta taccttgctg cttcaaataa gtaagacctt
    50521 ctgtaattga ttgttctcga tcaataaaga cacagcttgc ctgttttccc ttgatttctt
    50581 cacaaaaaac tagaggtcca tatttttgat atgccaataa atcatctagt gtattggcac
    50641 gagacgtaat gatcaatcca tcgaaagctt tagctgcaaa ttcttcaaga taccttcgct
    50701 ctttttcttt ctgatagccc gtcggtaaaa gtgtcacttt gtaatcataa tcaaacgctg
    50761 cttcaatgat cccactgatc aactgatcaa aatacggatg attggtataa ggcagaatca
    50821 ctccaatgct tttcgttttt ccataactta actgtctggc atttgcatta gggatataat
    50881 cgacttcttt catgaccgca agtatttctt tccttttttc ctcatctaca tatggatgtc
    50941 cattgattac acgtgaaata gtagaaactg aataacctgt gagctttgcg atatctcgaa
    51001 tgtttgccac tgctgcttcg ccacctatac aaaaagattt tcttgtaaat agtctaccac
    51061 agctggaccg cattcaaaaa actgatacat ttttccttca tgcgaaaaac tgatccgctg
    51121 cccgccccaa tatatatctt ttgtcaaatt ttcgatttca ttcattggta tttcttttac
    51181 tatattccta ttcaaccctt gaaaactgta caacgttaat acggatccct tgaactcgac
    51241 aaacgcataa aaataattgt tcgttgtgcc atctgttatc tctacataag tattcattgc
    51301 aagccctcct tttgatactt tgagtatagt gtatgaaacg cgtctcatag caaggagttt
    51361 gttttgccaa agaaaagttt tattcctctt tcattattac caaagtctct tattttaaat
    51421 tgaatacatt ataatgatac tgtaaatata tctttattat tagtgaatgg atatttactt
    51481 ttaatagata aaatattata actattaaaa ataactattt tcattataat tacacacaaa
    51541 aaagagcgtg agacaaaagt aaagaacact tttgtctcac gctctaaaca cgtataaaca
    51601 gcggaagcag aagcaactcc ttcggaaata agctgaaatt cacaaaaatt tgaaaagcaa
    51661 tttccgtgaa tttcttctta tttcttggag ttaaacgctt ctgttccagc ctctttttat
    51721 ctgtctttca ctaatgatca gttgtagata agcaagttgc tttttcttac atcataccgc
    51781 ccatcaagac aaacgttttt agcttgtacg tactggacaa aaatcccatt atatcaagaa
    51841 aaaacaacgt tgataatact taaaattatt aggctagaac ggactagtaa gagttttttg
    51901 cccctttttt gcccctcaaa tatcgcttta cagccagaac ataagttcgt ataatcgttt
    51961 tgaggtgatt tttatgatgg aagactttat tagaaaaaat atcagtgatg aatatgcaga
    52021 cttttatgag caaagcagca aaaaagataa attccagatg gatgtttcaa ttttagctat
    52081 attagctttt tccgaaaata aacaacctgt aactgcaaaa aaagaaacag tattctctga
    52141 aggcaaaata aaaactcgat atatattaga ggtagaaact aagtttaaaa atagatcgga
    52201 gtaatggcta tgctttttaa tgagacgcaa ttatggttta aattcgatcc ttcgaataga
    52261 tttgtcaaag atttttataa ggtgtgggat tcagaagttt tctttttagc aatcgaagat
    52321 agcttattaa tcaatctcta ctattctaat aagaactatt tcaaaattcc tgctgcgaaa
    52381 actagaatga agaaggatgt atactttttg tttgatatcg tgactgacgt gccggacgca
    52441 cgtagcgatc atcggcgtta tgactatata aagtatactt tcgttgatcc agaaagatac
    52501 aaagattaaa taaaaaaata acaaacaaac tcgcttgaaa ttcattaggt gagtttgttt
    52561 attatttttt ctgcttctcg attcatcagc gccatatctg ttttcgtaat ggtttcatta
    52621 ggaatatagt cagcacattt tcttttctct aacattctat acccactatt atgtattcct
    52681 aaggtattca attccttaac tgttgaaaac aaattccaaa cggtttggtg gcttcctttt
    52741 ccgctacttc cattataaat aatatcataa ttttctttca aatactcatc agatttttta
    52801 aaagcactgt agtatgctct tgaaacagca gttcttctat aagattcttt agaattatat
    52861 ttatcatctg attcaatttg tttggaaata gataaatatt cattaaagtc aaacatttta
    52921 ttcccccaaa gttgctacta cagatttccc catatattta tagtcagata atacattatc
    52981 gagagtatcc aaaacatcgt aatctgagga aaacaattca gatgttgttt tgataacaaa
    53041 gaaatacaag tttaaatctt catcatattt tatattgatt tcagcttttc tttttaaaac
    53101 cgtatttatc acatcaaaaa ttttgccatc attacttgaa attgtgttaa tctcattttt
    53161 tgtagtaatt acaagttgat tatcattttt agttttcgga gtagaacttg catccacaac
    53221 aactggagat gctagaatta ccgatgcgca agcaaaaatc gcagcaaaat ttattaagct
    53281 accactccga tgtgtatttg atggtactat atcaagcatc cgtatcgtct ccttaatttt
    53341 tttccactgg tttgttgacc ttgatatcaa agatttgcct tccaatctca gttccattaa
    53401 atttaacaac agcataatgc tctcctgctt cttcaaccaa gacatttctg gcgtttatat
    53461 taaagtttat atcgttaact tgaggaggca agcttaccga tacttcaccc gtagaaaaaa
    53521 tttgtttttc attcttgttt aaaacttcaa tttctactat ttttatcttt tctgtatcct
    53581 ctatctcaga caccacagct gttacagaaa atgataaagc agtaggaatt aaaggcgcat
    53641 taatagaaag agctggatta attactttat taataacatt agtgccaaat tgctgacttt
    53701 ctacatcttc tgaaattatt aattgtactc tataagacat tgatttctcc taatttttac
    53761 atttatttaa taaatttatg tttcactttt gctagtcaat ttagtttaac aatagtaaca
    53821 aagctttgtc aacggaaata ttagctaatt ttgtaagcat atttataagt atatttgtaa
    53881 gcatatctga catttaatca gtagtaaaag tgcctctata taaggaacaa actgtttttt
    53941 tactatctaa attcgtatac agttttacta acaaattagc taacaatatt agcaactata
    54001 tcaacaacta ta
//
LOCUS       DADGKS010000013        53103 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.013, whole genome shotgun sequence.
ACCESSION   DADGKS010000013 DADGKS010000000
VERSION     DADGKS010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 53103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53103
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.013"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(32..907)
                     /locus_tag="JXV47_000837"
     CDS             complement(32..907)
                     /locus_tag="JXV47_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAX1486896.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            1055..1387
                     /locus_tag="JXV47_000838"
     CDS             1055..1387
                     /locus_tag="JXV47_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAX1486897.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            1499..2707
                     /locus_tag="JXV47_000839"
     CDS             1499..2707
                     /locus_tag="JXV47_000839"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HAX1486898.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            2861..3316
                     /locus_tag="JXV47_000840"
     CDS             2861..3316
                     /locus_tag="JXV47_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486899.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            3678..3953
                     /locus_tag="JXV47_000841"
     CDS             3678..3953
                     /locus_tag="JXV47_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486900.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            3966..6044
                     /locus_tag="JXV47_000842"
     CDS             3966..6044
                     /locus_tag="JXV47_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAX1486901.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            6204..8090
                     /locus_tag="JXV47_000843"
     CDS             6204..8090
                     /locus_tag="JXV47_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAX1486902.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            8102..9049
                     /locus_tag="JXV47_000844"
     CDS             8102..9049
                     /locus_tag="JXV47_000844"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAX1486903.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            9069..9596
                     /locus_tag="JXV47_000845"
     CDS             9069..9596
                     /locus_tag="JXV47_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAX1486904.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(9659..10312)
                     /locus_tag="JXV47_000846"
     CDS             complement(9659..10312)
                     /locus_tag="JXV47_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAX1486905.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            10444..11286
                     /locus_tag="JXV47_000847"
     CDS             10444..11286
                     /locus_tag="JXV47_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAX1486906.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            11444..12340
                     /locus_tag="JXV47_000848"
     CDS             11444..12340
                     /locus_tag="JXV47_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAX1486907.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            12343..13056
                     /locus_tag="JXV47_000849"
     CDS             12343..13056
                     /locus_tag="JXV47_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HAX1486908.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            13076..13594
                     /gene="msrA"
                     /locus_tag="JXV47_000850"
     CDS             13076..13594
                     /gene="msrA"
                     /locus_tag="JXV47_000850"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAX1486909.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            13591..13818
                     /locus_tag="JXV47_000851"
     CDS             13591..13818
                     /locus_tag="JXV47_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HAX1486910.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            13970..14521
                     /gene="lepB"
                     /locus_tag="JXV47_000852"
     CDS             13970..14521
                     /gene="lepB"
                     /locus_tag="JXV47_000852"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAX1486911.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(14604..15146)
                     /locus_tag="JXV47_000853"
     CDS             complement(14604..15146)
                     /locus_tag="JXV47_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAX1486912.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(15383..15781)
                     /locus_tag="JXV47_000854"
     CDS             complement(15383..15781)
                     /locus_tag="JXV47_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAX1486913.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            16041..16901
                     /gene="ylqF"
                     /locus_tag="JXV47_000855"
     CDS             16041..16901
                     /gene="ylqF"
                     /locus_tag="JXV47_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HAX1486914.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            16894..17661
                     /locus_tag="JXV47_000856"
     CDS             16894..17661
                     /locus_tag="JXV47_000856"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HAX1486915.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            17717..18574
                     /gene="dprA"
                     /locus_tag="JXV47_000857"
     CDS             17717..18574
                     /gene="dprA"
                     /locus_tag="JXV47_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HAX1486916.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            18696..20774
                     /gene="topA"
                     /locus_tag="JXV47_000858"
     CDS             18696..20774
                     /gene="topA"
                     /locus_tag="JXV47_000858"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HAX1486917.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            20743..22119
                     /gene="trmFO"
                     /locus_tag="JXV47_000859"
     CDS             20743..22119
                     /gene="trmFO"
                     /locus_tag="JXV47_000859"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HAX1486918.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            22317..23222
                     /gene="xerC"
                     /locus_tag="JXV47_000860"
     CDS             22317..23222
                     /gene="xerC"
                     /locus_tag="JXV47_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HAX1486919.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            23259..23807
                     /gene="hslV"
                     /locus_tag="JXV47_000861"
     CDS             23259..23807
                     /gene="hslV"
                     /locus_tag="JXV47_000861"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HAX1486920.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            23821..25221
                     /gene="hslU"
                     /locus_tag="JXV47_000862"
     CDS             23821..25221
                     /gene="hslU"
                     /locus_tag="JXV47_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HAX1486921.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            25239..26030
                     /gene="codY"
                     /locus_tag="JXV47_000863"
     CDS             25239..26030
                     /gene="codY"
                     /locus_tag="JXV47_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HAX1486922.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            26112..26987
                     /locus_tag="JXV47_000864"
     CDS             26112..26987
                     /locus_tag="JXV47_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HAX1486923.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(27119..27757)
                     /gene="plsY"
                     /locus_tag="JXV47_000865"
     CDS             complement(27119..27757)
                     /gene="plsY"
                     /locus_tag="JXV47_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HAX1486924.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            27884..28318
                     /locus_tag="JXV47_000866"
     CDS             27884..28318
                     /locus_tag="JXV47_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HAX1486925.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            28484..30529
                     /gene="parE"
                     /locus_tag="JXV47_000867"
     CDS             28484..30529
                     /gene="parE"
                     /locus_tag="JXV47_000867"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HAX1486926.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            30541..32991
                     /gene="parC"
                     /locus_tag="JXV47_000868"
     CDS             30541..32991
                     /gene="parC"
                     /locus_tag="JXV47_000868"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HAX1486927.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            33268..35499
                     /gene="pflB"
                     /locus_tag="JXV47_000869"
     CDS             33268..35499
                     /gene="pflB"
                     /locus_tag="JXV47_000869"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HAX1486928.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            35743..36504
                     /gene="pflA"
                     /locus_tag="JXV47_000870"
     CDS             35743..36504
                     /gene="pflA"
                     /locus_tag="JXV47_000870"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HAX1486929.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            36589..37515
                     /locus_tag="JXV47_000871"
     CDS             36589..37515
                     /locus_tag="JXV47_000871"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HAX1486930.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            37697..38590
                     /locus_tag="JXV47_000872"
     CDS             37697..38590
                     /locus_tag="JXV47_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HAX1486931.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            38724..38849
                     /locus_tag="JXV47_000873"
     CDS             38724..38849
                     /locus_tag="JXV47_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1486932.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(38983..39615)
                     /locus_tag="JXV47_000874"
     CDS             complement(38983..39615)
                     /locus_tag="JXV47_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486933.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(39763..40305)
                     /locus_tag="JXV47_000875"
     CDS             complement(39763..40305)
                     /locus_tag="JXV47_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HAX1486934.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            40440..40829
                     /locus_tag="JXV47_000876"
     CDS             40440..40829
                     /locus_tag="JXV47_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486935.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            40833..41597
                     /locus_tag="JXV47_000877"
     CDS             40833..41597
                     /locus_tag="JXV47_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAX1486936.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            41726..42673
                     /locus_tag="JXV47_000878"
     CDS             41726..42673
                     /locus_tag="JXV47_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAX1486937.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            42803..43543
                     /locus_tag="JXV47_000879"
     CDS             42803..43543
                     /locus_tag="JXV47_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486938.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(43834..44502)
                     /locus_tag="JXV47_000880"
     CDS             complement(43834..44502)
                     /locus_tag="JXV47_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAX1486939.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            44636..44923
                     /locus_tag="JXV47_000881"
     CDS             44636..44923
                     /locus_tag="JXV47_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486940.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            45339..46877
                     /locus_tag="JXV47_000882"
     CDS             45339..46877
                     /locus_tag="JXV47_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HAX1486941.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            46874..47839
                     /locus_tag="JXV47_000883"
     CDS             46874..47839
                     /locus_tag="JXV47_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1486942.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            47826..49148
                     /locus_tag="JXV47_000884"
     CDS             47826..49148
                     /locus_tag="JXV47_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAX1486943.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      49211..49315
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            49389..50132
                     /locus_tag="JXV47_000885"
     CDS             49389..50132
                     /locus_tag="JXV47_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1486944.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            50147..51139
                     /locus_tag="JXV47_000886"
     CDS             50147..51139
                     /locus_tag="JXV47_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAX1486945.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            51151..51888
                     /locus_tag="JXV47_000887"
     CDS             51151..51888
                     /locus_tag="JXV47_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1486946.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            51878..52600
                     /locus_tag="JXV47_000888"
     CDS             51878..52600
                     /locus_tag="JXV47_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAX1486947.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(52684..>53103)
                     /locus_tag="JXV47_000889"
     CDS             complement(52684..>53103)
                     /locus_tag="JXV47_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HAX1486948.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT        18306 a         9116 c        11118 g        14563 t
ORIGIN      
        1 ctttcctcat agcctatctt tgtctttttt cttatagttt tttcagtaat cttgtctgtg
       61 gcttcaaata agtaaagcct tgcccttcca cttcatgcac attgatgatt gaaaggaaag
      121 ctttttcgtc aatctcgtgg acgatcctct tagcttcagt taattcacta gagctaacga
      181 ccatatagat gatttttttt gaattaccag agaatgcgcc ttctccagaa aggaaagtca
      241 cacctctttg cagaccggtc atcagtagtg gtgcaatctc ttcgcttttg ttggagacga
      301 caagtagacc ttttgcagaa tatccgccat ctaagatcga atcaatcaca cgactgaaaa
      361 catacgaaac aatcaacgta tacatcatac gtttcaagtc gatataggtt aatgaagcaa
      421 gtaagacgat gatatcaaat gccaataggg aacgccccat agtgatgccg taattttgtt
      481 ctaaaatccg agcgataata tcactgccgc ctgttgttcc acccatgcgg tagacgatcc
      541 cgcttcctac acctgcaact aaacccgcaa gtagagaaac gatcagtaga tcatgctgta
      601 aattgatttc tagtggaacc ctttgccaga tccataaaaa gaatgacaaa gaaagtgtac
      661 ctagaacagt ataggccaag gaacgtttac cgaggatctt tcctcctagt aaaatcaatg
      721 ggatgttgat taataaagtc gtataagctg gatcaatacc aaataaagct cttaagatca
      781 aggtgatccc tgagactccc ccttctgcta aatgattagc gatgttcaag taaacaagac
      841 caaatgcata aatacttgtt cctataatga taaaaagaac ttcttttact gtttttcgtt
      901 tgaccatatg aattccagct ttcaattatg tattttcaca gaatttccat ttagaaattc
      961 cttcctaaat gtagcatgga aattcgattt tctcaattgc tcttatctag gatttgcgtt
     1021 aaagttttgg taagatagtt ttggagggaa aaagatggat aaaaagcgtt ctttatacag
     1081 tatgcagcag gaagtggatg aatatatcca gcaattcaag gtggggtatt tctctccatt
     1141 agctcagatg gctcgattaa ctgaagaagt aggtgaattg gcaagagaag tcaaccacac
     1201 ttatggagaa aaaagcaaaa aggcttctga accagttaac tcggtagcag aagaacttgg
     1261 tgatgtttta ttcgttacga tgatcatggc taattcattg aatatcgact taactgaagt
     1321 ttttgaaaaa aacatggaaa aattcaatca aagagaccat aatcgctttg agcgtaagga
     1381 cgagtaaaca agatgaagtg gtcctggcct tgaagactct gaaacggact tgtcaaacag
     1441 tcaccatgca actgagtctt tatctcagga caagaaacac gcaggaaagg ttggaaaaat
     1501 gaaattaaaa caattacctc tggaatacca aaaggcaatt ccagttctga aaaaattaga
     1561 gaatgcagga tatgaagctt attttgtagg tggaagtgtt cgtgatatct tgctgaacca
     1621 gccaatccat gatgtggata tcgcaacaag cgcatttcca gaagaaatca aacagctttt
     1681 tccaaaaacg atagatattg ggatcgaaca tggaactgtg ttggtattag aaaatgatga
     1741 acaatatgag atcaccacat ttcggacgga atcaacttat caggactacc gtagaccaga
     1801 tcatgtcgaa ttcgttcgtt cgttggcaga agatttgaaa agaagagatt ttacgatcaa
     1861 tgcgtttgct ttgaaagaag atggagaaat catcgatttg ttcgatggtc tgcaagatct
     1921 agaagaacag atcttgcgag ctgtaggcaa tcctcatgag cggttccatg aagatgcctt
     1981 acgaatgatg cgcgggttgc gttttgtcag tcaactaggg ttcaaattag aggaagaaac
     2041 cttctacgcc atcaaagaaa accacgagct attaggtaaa atatctgtag aacgtataaa
     2101 tgtggaattc atcaagatgc tcttgggaaa tgaacgggcc gcgggaatcc atgcatttat
     2161 tgaaacagag tgctacattt gctgtcccgg tttgaaagaa gaaggcgaag cacttttacg
     2221 ttttgctgaa ttaccatccg tcccattgaa agaagagagc caagcatggg cattattgat
     2281 cagccaactg gatctaaaag aaaatgagat tcgttccttt ttgaaatcgt ggaagtgttc
     2341 taaccaaatg attaaagacg ttcaagcact tgtccaagga ctacgacaac gagaaactgg
     2401 agctttggaa ccattcgaat tgtacttctt aggcaaaaaa catgcactgc aagtagaaga
     2461 attgatgatc tattttgacg aaacacctca gatggatgcc gtaggagaat cctatgatcg
     2521 tttacctatc aagtcattaa gcgaattagc agtagatggt aaaatcttgc tagaagaaac
     2581 tggaaaaaaa cctggtaagt gggttagtga agctttgcaa ttagctgaaa aagccgtcgt
     2641 agaacaaaga ataaaaaatg ataaaaaaca ggttttggat tttttatcga aagaaaaatt
     2701 gatttaaaaa acactagact gtatctgctc agctttgttg gctacttaaa gtgggcagat
     2761 acgtcattag aagaaaaaac ataagatgtg accacttaca taaatttgtg ctaaactgag
     2821 gtagtacaag aataaattac atcataaagg agtcttttta atgagtaaag aaatgacagc
     2881 gctaaaattt tattttagaa atggagaaac ctggacgatc aaccgccgtc atatcggcga
     2941 tctttggatc aaacaaatca caacaagttt tggacgaatc aatggcagtg aatttgttga
     3001 aatccatccg tgtgctggat ttaaaatcga aatcttccat gaaggggacg cagttgcgac
     3061 acatgatatc aacctaggcg gactggaaat gggcatgttt aatcgcgcat tgaaatacga
     3121 agatatcgag cgaatggaaa tcctttaccg aaatggcaca cctgatcttg tgtacttccc
     3181 atatctagat aaaggaacag aaggattaga caatcaatat caatcaacaa aaatcagcga
     3241 aaaaacaggt aacttgtata tcgtgatcaa tccagatcaa cgtgtagaag atgtatacgg
     3301 ggaatttttc gaataaatcg atttttacgc aaaaatgagg ctgtgaaaga gatgtgtctt
     3361 attactactg ataggctgtc tcttccacac cgtttattca gaataaggga ctgtgacaag
     3421 atttttgtcg cagccccatt tttttgttgt gataaaagaa caagaaaggc aggaatggga
     3481 aagtaaacat ccttttgtca gaaactttta tctttcttaa gttttacttg atatctgata
     3541 ctatttggaa tagaatgagg cgttgaaaaa tttatggaaa tttctaacta gcaataaacg
     3601 atgaaacaat gaaatatttt tcatccaaaa agaactttgc tataatgatg gaagtttgtg
     3661 tataggagat ctggaaaatg agagagagtt ttgaacaaca aaaaaaactg ttgcatgatc
     3721 gctatggcgc cctttcgatg gatgaccgcc gtcaaatact ttgtaagttg cgtaaaagaa
     3781 atatattgat gtatcgtcag ttggaacgtc tgaaacatga tctgcttcgt ttggagtcaa
     3841 aacgtgtaca gtgtgaatta gaggggaacc aaacacaggt tgaagtagtc gaaaccaaaa
     3901 ttttaaagaa aaaagaacaa tttttaaaaa tgcttacaca aaataaaaaa taaaggggat
     3961 ggacgatgga atttgctgag ttagttattg tatttgcagt aacgatcacc ttatcgaaca
     4021 tagctagccg cattttgcca atgattccag ctccactgat ccaaattttc cttggagtgg
     4081 tattaggtct gacagagtgg ggacaatcaa tcgattttga acctgaattg ttcttagtta
     4141 tgattattgc accattgtta tttagagaag gagaaaaagc agatatttct tcgattctca
     4201 aaaatttcgg gacaattttg ttcttggcat ttggaggagt cattttgacc cttgtcgggg
     4261 taggtgcgac gttatcattc ctgttgccaa gtgtcccact tgctgcctgc tttgcttttg
     4321 gagcagcgtt aggtccgaca gatgcggtag cagtcagttc tctttctgga cgagtgaata
     4381 tccctaaaaa ggcgatgcat attttggaag gagaaggtct tttgaatgat gcatctggtg
     4441 ttactgcctt ccagtttgct cttggtgcgc tgatcaccgg atctttttca gcagtaaacg
     4501 cggggatgag tctagtagtt tctagtattg ggggagcttt gatcggcttt ttgcttgtct
     4561 ggttcaaaca aaaaataatt catttgatcg aaaaagcatc agcacaagat gtcacagggt
     4621 atctgctgat cgaacttttg cttccttttc tagcctatgt attggcagag gcatttgatg
     4681 tatctggaat cattgctgca gtggcagcag gtattctcca agcttctggt tttaggaaaa
     4741 tctctgtgtt tgatgcagaa ttgtcgagct tgtcccacag tacatggaca actattgctt
     4801 ttacactgaa tgcattagta tttatatttt taggaatcga attgacgcaa gtgttctcgc
     4861 cagtatgggg agacggttta tatccaaacg gtcttttatt agcgattatc gtattaatct
     4921 ctgtcatgct ttttgtgatc agattcattt ctatcagtct tttttatgta ttcaaagatg
     4981 gcagtaaaaa gttcaaaaaa cagttgaacg agatcttgat cttaacattt ggcggtgtaa
     5041 agggaacagt cagtttggct acgattttta ttttgccatt ttcaatcaat aatatgatgt
     5101 tttaccagcg gtctttgctt ttgtttctga cggcgggtgt catcttagtg actttggtca
     5161 tagggatcat tgtcttgcct atgctgacgg aaacagagga agcgaaaagc acggatttga
     5221 atgctttgat gattttagaa gaggtcgttg aagttttgcg aaaagaaata aaggaaattg
     5281 atcgtaatac aaaagaattt ttagccactg aagcagtgat agaaaattat caagaacgga
     5341 tacgtgatct gtacttggaa gatttaaccg atgatgaaaa gcaagaagta caagaaatac
     5401 aagcactgat tttgtcgatc gaacgggatg gattggatga aagttatcgt tcgggcaagc
     5461 tttcttctaa tggttatcgt ttttactccc gttttctttc tcgattcgaa cattctatca
     5521 caagccagat tttgtctttt atcggctttt ggttcattgt tgtccgtagg ttaatgcgaa
     5581 tcgttctcca tccgaaaatg ttttggcaaa gaagatatgc tgatcgtcag acatttatta
     5641 gtgatgaaga tatccaagaa atcagagaga catatcaaaa aaatactcag ttgattattg
     5701 aaagtttaga taacttgact gatatttatg atgaaacgat ggttcaattt tttatccagc
     5761 aacgcaaact tgaaggaata aaaatgaact cggggaattt gatttcttcg tggatgatcc
     5821 agcaagatag tctgtttacg aaaaaaatgc taagaggtta ttatcttgaa agaaaaatca
     5881 ttgatgaata cgaagttgct gaaaaaatca cgacgttttc tgcgaacagc tatcgcagga
     5941 atatcaattt gttagaatct tatacgatga acaaaccatc tgataacttt tctttccgat
     6001 ttgcgtttcg agcaaagtca aaaaaaacga gtccaataaa ataaaaaggt aaaaattttc
     6061 aagttttata aaaaacaaaa catatcagaa caggatcgaa tcggtcctgt tctttttttg
     6121 agaacacaaa aagaacaaat accaaaaaaa ttttcctgaa gttcactatt tttatgatac
     6181 aatatccaag ataaggaggg aacatgttga aagaattaaa agtaactgac ctcaaaaaaa
     6241 cttatggtga aaaagatttg tttgaccaga tttctttttt ggtccacgaa aaagaccgta
     6301 tcgggttgat tgggacgaac gggacgggta aaacaagtct cttaaatatt attgccggta
     6361 tcgatagcag cgacggtgat cggcaaacag tgttttatcc aactgattac cgtattggtt
     6421 atctttctca agcagctgaa ttttccgatg aattaactgt tctccaagca gtctttcaag
     6481 gaaacagccc cttgatccaa actgttcgag catatgagga agcattgatc gaactagggg
     6541 aaaacggaga agaccctgat gtgcaaaaac gttatgctaa agcagaagaa caaatgaata
     6601 aagaagatgc ttggactaca gataccaacg caaagattat tttgcaaaaa ttaggaatca
     6661 gtgaattaga taaaaaaatc agtactttat caggtggtca gaaaaaacga gttagtctgg
     6721 cgcaagtgtt gattgatgaa cccgatttac tattactaga cgaaccaaca aaccatttag
     6781 attatgaagc gatcgagtgg ttggaaaact atttgaaaca ataccgtggc gcactattga
     6841 tggttaccca cgatcgttat tttctagata gagtagcaaa ccgaatcttc gaactttcat
     6901 ttggaaaatt atacgagtat aaaggaaatt atgaagctta cgtcttagaa aaagcagaac
     6961 gtgatcgtgt agaagtagaa caagaagaaa agcgcaagcg gctttataaa caggaattag
     7021 cttggatgag ggctggcgta caggcacgtg gcaccaagca gcaagcacgg atcaaccgtt
     7081 tcgaagatct aaaggagaac ttgtaccaag taaaccaaga agatgattta gagctgaacc
     7141 tagcgacaca acgtttaggg aaaaaagtac tggaaatcaa agatggcagt taccgtataa
     7201 atgaccaaac actgctagaa catttagatt tattgattca atctcgggaa agactaggta
     7261 ttactggtaa aaatggtgcg ggaaaatcga cattgcttaa tattctagct ggcagaattc
     7321 ccctggatag cggtacaatg tctatcggtg aaacggttca tcttgcgtat tatacacaag
     7381 aaaatgaaga aatggcacca gataaacgga tgattgctta cttacaagaa gctgctgaag
     7441 aagcaaaaac agcagatggc agtcaaatcg gagtagcaga attacttgaa cgatttttat
     7501 ttccaagatt tatgcatggg acactgatag gcaaactttc aggcggagaa aaacgccggt
     7561 tatttttgtt gaaactgctg attcagcaac ctaatgtttt attattggat gaaccgacca
     7621 atgatttgga catagcaaca ttgacgattt tggaagatta ttttagaagt tttccaggtg
     7681 ctgtgatcac tgtttcccat gaccgttatt tcttggacaa ggtagcagat aagttattag
     7741 tattccaagg aaacggaaaa caagaacttt attacggaaa catgtccagt tatttactga
     7801 agcaaaaaga gacccagcag cctgctgaaa aagcgaaacc aaaaatacag agcaaggaac
     7861 ctgctgaaaa gaagaaatta tcttacatgg aacaaaaaga atgggaaacg attgaagatg
     7921 agattgcaga acttgaagaa aaaatctcat tgctccaaga agagatgaat catcaaggag
     7981 ataatttcac tcgattacaa gaattgcaaa acgacgtatc tgaaacagaa gcacaacttg
     8041 aagaaaaaat ggcacggtgg gaatacttga gtgaatgggt agaagattag gaggaaaaag
     8101 gatggaacaa gcgtatcttg acttaggaag aaaattgttg gaagaagggc atcgtaaaga
     8161 agacagaaca ggcacaggca cattaagctt attcggatac caaatgcggt ttgatctgca
     8221 aaaagggttt cctttgttaa caacgaaacg agtacctttt ggattgatca aaagcgaatt
     8281 gctttggttt ttaaaaggag atacgaatat ccgctatcta ttacaaaata aaaaccatat
     8341 ttgggatgaa tgggcatttg aacgctacat caaaagtcca gactataatg gaccagatat
     8401 gactgatttt ggccatagat gtttgacaga tcctgaattc aatgaagaat ataaaaagca
     8461 gagcaagctt ttttgcgaga agatcctaac cgatgattcc tttgctgaaa catacggcga
     8521 tcttggacac atctacggct atcaatggcg tcactgggaa acaaaagacg gtggctttat
     8581 cgatcaaatc aaacaagtga tcgaagcaat caaaaagact cctgattcta gaagattgat
     8641 cgtttctgca tggaatccgg aagatgttcc tagcatggct ttgcctcctt gtcatacgat
     8701 gtttcaattt tatgttcaag agggacggct aagctgccaa ttgtatcaac gcagtgggga
     8761 tgtgtttcta ggcgttccgt tcaacattgc aagttatgcg ttgctgactc acctaattgc
     8821 acatgaaaca ggtttagcgg ttggcgaatt tgttcacaca ttaggagatg ctcatcttta
     8881 tatcaatcat atcgaacaaa tgaaagaaca attgagccga gaaatacgcg catttccgac
     8941 tttagttttg aatcaggaaa agcagtcagt atttgatttt gagatggaag atatccaatt
     9001 agaaggatat gacccacatc cggcgatcaa agctcctatc gctgtttaga atcagaaagg
     9061 atgagaaaat gttagctgca atttgggcac aggatgaaaa cggattgatt ggaaaagaag
     9121 accgtcttcc ttggcgtttg ccaaatgatc tgaaattctt caaacaaatg acagaagcaa
     9181 atacactagt gatgggacga aaaacattcg aagggatggg tagccgtccg ttgccgaatc
     9241 gtcagacgat tgttttgacg agagattctt cctataaagc agaaggcgtg catgtcatgc
     9301 atagtgtgga agacgtgctt gctctggaaa aagaaacaga cggtatcttt ttcatcgctg
     9361 gagggtcagc tgtttatcaa gaatttctgc cattttgtac gatattatac cgtacagtca
     9421 tccatcatgt attcgatgga gatgcttatt ttccacctgt tgactggtct gattggtcac
     9481 tgatcaatac tagtcaagga gaaatggatg aaaaaaatcg ttatccgcat caatttgaaa
     9541 cgtatcagcg taatgagaat cctgtaaaaa gcgggacagg cgaattgacg atataaaaaa
     9601 gctatggata gactagctgt tatttagagc tgtcccatcc atagctttat tttttttatt
     9661 aagtaaagaa taaaacagag aagtacataa aacctgcacc taacataaca aacaaatgcc
     9721 aaacaacatg catatagcgg atagaattca agctataaaa gaatgcgcct atcgtgtaag
     9781 aaagcccgcc tgctaccatc aaaataacac cagtcattcc aagagagtga taaagaggaa
     9841 cagcagccac gacacagagc caccccataa aaatatagat gatcgtagat acttttgata
     9901 ctctctcccg tttatgcaac gtcaacgctt tatatataat gccaagaatc gcaaacaacc
     9961 agattaatac aaataaagtc caacctagcc atcctcggat actcagcaaa caaaaaggag
    10021 tataacttcc tgcaatcaaa agaaaaatcg aactatgatc gaatacttgg aacacctttt
    10081 ttgcttttgt aaaaatcaat gaatgaaaca aagtagacgt taaaaataaa agaatcatca
    10141 tcgatccata gatagcataa gagacaatat ggagggagga atgcaagtgg gcacctttta
    10201 ctaaaagaac cactagtccc gcgatactca atccagtccc aattccatgg gtgactgcat
    10261 taaacacttc atttaatatt tcatacgttc gattaaattt cgttttttcc atgaaaacgg
    10321 ctcctttact aggtgtaatt aatgaaaaat cattatttgt ctgttatact aaaaatagaa
    10381 attgtcttac atgtagttta acatgaataa ggcatcttgt taaagaaaga gagagagaaa
    10441 ataatgacaa atgtaaaaat cgtaacagat tcttcatgta cgatggaaaa aaatgtacgc
    10501 gatgctttag gcattcgtgt catgccgcta tccatcatga tcgacggaac agtatatccc
    10561 gatgatgacc aactagacgg cgaaagattt atggaaatga tggcgaaagc aaaaaatctg
    10621 cccaaaacaa gccaaccacc aattggagaa ttcatctcga tgtatgatga gctaggagaa
    10681 gacggcagtg aagtgatttc gatccatatg acaaaaggct tgagtggaac agtagaagca
    10741 gcaagacaag ccagtaatct aacaaaaacg aaagtaacgg ttatcgacag tgataccact
    10801 gaccaaggat tatcttttca ggtaattcga gcagctgaat tagcaaaaga aggtaaaaca
    10861 gtagagaaaa tccttgaaga agtcaaaaaa gtacaagaca atacaaaatt atacatcgga
    10921 atatccacac tagataactt ggtaaaaggt ggaagaatca gccgaacaac tggtttgctg
    10981 tctagtgttt tgaacatacg cgtggtgatg aatttcgccc attctgaatt aatccctgta
    11041 actaaggggc gaggaaagaa aacgttcgat aaatggttta ataatttgaa aaatgaactg
    11101 aaagaattgc caaatgtgcg acaaatcggt atttcacatg cggatgcaaa agaattggcg
    11161 caagaattca aagagggttt gcaagaatta ttcccggaca tgcatatccc tgtactgcat
    11221 acgaatccgg ttatcgctac gcatactggt aaagacgcgt ttgcaatcat gtattatgta
    11281 gattagtcga aaagaggata agccctcagc ctgaaaggct tgcagcttat tctctttttc
    11341 tttataaaat taggaaaata attgttttct tttttcataa agactacctt tttgataaaa
    11401 tttttgataa cattagaacc aatcgaatac aagaggtgaa aaaatgaaat taacgaaacg
    11461 acatttgatc ctcgttttgt tcccattatt aattgcgatc atcatctatg caggtttagc
    11521 tgcttctata ccgaaagctg gcccactaat gaaaccagta actactgtga gagaagatcc
    11581 aaataaaaaa gaaaaacttc actacatagc tatcggagat tcgctgactg aaggagtagg
    11641 agatcaaacc aagcaaggag gattcgttcc ccttgtcgca aatgatctaa aagaccgtta
    11701 taatttgacc gcggttgaaa cagaaaacta tggtgtaaat ggtgaacgaa gtgaccagat
    11761 cttaaagcga gtaaaaacaa aagaagaaat tcgaaacaat atcaaaacag ctgattttat
    11821 cacactgact gttggcggta atgatttgat gaaagttatc caaaataatt tattcgggtt
    11881 aacggtcaat tcctttaaaa agccactgaa aaactatcag gaaaatgtca cagaactatt
    11941 ggaagaattt cgatccctca ataaaaccgc acctatttac attttaggca tctacaatcc
    12001 attttatttg aactttcctg agatcactga catgcagaca attgttaaca attggaacaa
    12061 aggaacagaa acggtgacaa aaaaaatgcc gaactgctac tttatcccaa tcaatgattt
    12121 gctttatcaa ggattgaatc aggaagtagg tgtcacagaa gaaggaacag atcaaacaac
    12181 tagcacgaca gaaaatctaa atggcatcaa aaataatgtg ctctatgaag aagatcattt
    12241 ccatccaaat aatttaggtt atcaattgat ggcaaatgca gtgagagatc agctgatcga
    12301 gacacaaaac caatggttag agaaggagga tgatcaataa acatgaaaac aagatctgac
    12361 gtatcttcaa acaaaacaaa gaaaacaaat tactggaaat tcgccttcct tatccttctt
    12421 ggggtagtac ttggttcgac cgtattttta ggcagccgta tttttgctaa tcgggaacca
    12481 gaactcccag aaataccagc tcttacggaa agacaaggag atcctgtctt aacgatcaat
    12541 tcaaataaag aaaaagtcaa tcaaatcatc agctttttcc ttagtgagta tcaaaaagat
    12601 agtgatattg aatataaatt ttatttggaa aatgaagcac tactcaatgg tactttcgaa
    12661 gtactaggtt ttcctatcga tttctattta tattttgatc cgtatgtgat ggaaaacgga
    12721 aatgtccaac taaaagctag aagtctttct atcggaacat tgagtttgcc aatcaaagat
    12781 gtgatgaata tgatcaagag aaactataaa ttaccagatt ggatcgaagt caatacagat
    12841 gatctgacta tcatgcttag gttggatcaa ttccgaatgc aaaacgggat gtatattaaa
    12901 gcagataaaa tcgacttagt aaatgatgac attcggttta gtctatattt gccaaaagat
    12961 acctctgatg cttcaaacaa ctcaaatacc aacaaaacta gcaccagcag tactgaaagc
    13021 aagacaaaag aaaataaaaa atcatcggat gagtagtatt agagggggaa tcataatgga
    13081 acgagcaata tttgcaggag gctgcttctg gtgtatgatc cagcctttcg acacgcttcc
    13141 tggtatccat acagtgatgt caggatatac tggagggcat gtaccagatc cgacttatga
    13201 acaagtaaaa agccaaacga ctggacatac agaagcagtg gagattatct atgatccaac
    13261 attgatttca tatgaacaat tagtagaact ttactggcag caaactgatc caactgacgc
    13321 tttcggacaa ttcgaggatc gcggtgacaa ttatcgcccg gtgatctttt atttgacaga
    13381 agaacagcgg atcattgctg aaaaaagtaa gaaacagtta gctgaaagtg gacgtttcga
    13441 acagccaatc gttacaaaaa tcgaaccagc ccaaccattt tatctagcag aagaagacca
    13501 tcaagagtat tataaaaagc atcctgaaaa ttttaaaaga aaccatgcac gccgggctgc
    13561 ctttatcgaa gaaaattgga ggaacgaagg gtgaatcgaa gcttttttca ttatttaatg
    13621 acactgcgag gcggtggcac acatgatgct ttatctgttt tcgctacaga agccggtaaa
    13681 gacatccaat ttcctaagca cagctctagc tacgaagaaa tttctaatta tctggaactg
    13741 aatgtcgact atttgccgtc catggatatc tttgacgaag catgggaaaa atatttagaa
    13801 aataatcatg acatataaga gatagttttg tactttatga tcaaaaaagt tttttgtcca
    13861 atagcctaat tgaaagaatt atttttattt cagctatcta gtcgcatttt tttgatattt
    13921 ttcttataat aaagaaagaa tgaaaaaaag agggatggat tgatagagat tgacaaaaaa
    13981 acaacgctat attaatcgct tctggcttgt attcaaatac ttacttgttt ctgtattcct
    14041 tgcgttcatg ttgcggggat ttttattcat cccggtacca gtggaaggca attcaatgga
    14101 aaacgtgttg aagcaaggtg atatggttgt gatggaaaaa ttttcggaga tcagacgatt
    14161 tgatattgtt gtttttcaat tagcagatgg cacgatttat atcaaacgag taatcggtct
    14221 tccaggagaa aatgtcagct accaaaatga tcaattgaag atcaatggga aagtagttaa
    14281 ggaaccttat ctaactaaaa acctgaaatc agatcatgca aatgcatcct atacgacgga
    14341 ctttacacta caagagctaa cgggacaatc caagcttccg gaagataatt attttgtact
    14401 tggagataat cgaagagttt caaaagatag tcgttcgttt ggcacgatca ataaaactga
    14461 tattctaggt aaagcaagat ttgtctatta tccacttgat gaaataaaat ggatccagtg
    14521 agaaacaata aagcgtgcag tctgttgaga ctgcacgctt tattgtttaa tccaaaatca
    14581 gtttactacc ttagtacgta aaatcaaaca gctcgtttaa acacttttct agcctctaaa
    14641 gttttgataa atgaataaac aaccattatt tgaataggga tttggatcat attcctgatg
    14701 aatctaccta gaaaaattac tttgaaatct gcaccaaaca aaacagacat cagccaagaa
    14761 ttgataaaaa ggctgactgg gatcataatc aataattggg cagcgatgac ggaaggcagg
    14821 tttatctttt tatgatataa aaataagcca ttaataaatc caccaaggaa agccgtgata
    14881 agaaaagcag cttgaaacgt tcctgaacca aatatcgtga aatttaaagt gttcgacaac
    14941 atttcaagca aaccagccca gatcggtcca tatagataac ccataagcgc catacttaaa
    15001 aatccgaatg tgatttgaaa ataagcagga ccaatcgcta tcttgtataa gatgacatca
    15061 agggctaata aaagagcaga ggtcgacaac aatcttgcat tcatttcggg caatctaaaa
    15121 acgtcttttg caatcaaagt gttcaaaata ttctctcctt tgtcagttaa taataaaagg
    15181 ataccataaa atcaccaatg tgtcatgaca cattggtgat ttacatacac tggcatctaa
    15241 caattaaaaa aagggtgaga agactgcttt tataaactgt aaaaaagaga ttgtacgaat
    15301 aaaaaaaata gaggcggaga atacttatcg tatcatccgc ctttgttttt ttgttataaa
    15361 aaacgtcaga ttagttatct gcttacatct tcatccatac gggttctaat gtatttccgt
    15421 ctagatcttg gacttctaat gaaaacattt cttcttcagg cattcccata tctacttcgt
    15481 ggaaagtacc accattttct tttgcaattt gagcaaattt ttttacttca tccgcatttt
    15541 caacactaaa cgaaatcaaa gcaccacttg tttttttatt atcagctatt tctttatctt
    15601 ttataaattt tttataaaaa tcatgagaga gaagcattat ccaaaaagtg tcatcccata
    15661 ccattgaacc agcttcttca gtagaaaatt cttcattttt tttaaaaccc agcttttcat
    15721 aaaaagcaac ggaacgattg acatcagcaa caggaaaatt aacaaaaacc atactattca
    15781 tttgtttcgt ctcctttctg ttttgttcgt ctatcatctc ttatttagga aacgctgtca
    15841 aaaatttaga ttcatatata gaaaccaaaa taaaaatttg catcatcaaa aaagtgaaga
    15901 tgtgatagaa tgaggactgg ttcactttca cttaactaat agatggaatt tctttataat
    15961 aaaaaagtga atttatattg aaaaagaaaa aaacaagtaa agccggggaa tattccggta
    16021 tgaaaggaat ggagagaaca atgaccatcc aatggtttcc gggacatatg gcaaaagccc
    16081 gacgagaagt ttctgaaaaa atgaaatatg tggacatcgt atttgaattg gtagacgcac
    16141 gattaccttt atcttctcgt aatccaatgc tagatcagat cattcagcaa aaacctcgcc
    16201 ttgttttatt gaataaagcg gatctggcag atccacaaca gacaaagctg tggcaagaat
    16261 attttcgtaa acaaggccat cttgcattag ctatcacggc acaagaaagt aaaggaatta
    16321 aaggtctagt acctgcggct aaagaagcat tgaaagaaaa acgggcaaga gatgctgctc
    16381 gggggatcaa gcctcgcgct attcgggcaa tggtcttagg tattccaaat gttgggaaat
    16441 ctacgttgat gaatcgacta gtaggcaaga aaattgcaca gacaggaaat aagcctggcg
    16501 taacaaaagg tcagcagtgg cttcgtttag gtaatgagtt ggaattgtta gacacaccag
    16561 ggattttatg gcccaaattt gaagatgaag aaatcggcaa aaaactagcg ctgacaggcg
    16621 cgatcaaaga ccagcttgtc catttagatg atttagcgat ttacggatta gacttttttg
    16681 cccgatatta ttcaggaaga atcagcgatc gttatggttt atcaatcgag caagaagaaa
    16741 aattggcacc ggaattactg atggatatta cagcaaaacg tgggtataaa gaagactatg
    16801 atcgtggcag cgaattagtc gtgcatgata ttcgtcaagg aaaacttgga cgatacacac
    16861 tggatcgttg cgaagaaatg gagcaaaaaa gtgatgactg aatccatcca aagtatcaaa
    16921 gaacgattga aaagcataca gagaatagat gatcctacac tagaatcatt aagaaatgat
    16981 ccacgcaaag gcgtgcagca agcactggct tcttttgaac gacgattgaa aaaggaagca
    17041 ttaattaagg aaaaatatga agaaatgttt tgctttgaaa agcaagggta cgcacaaggt
    17101 caccaatgga ttgccggcat tgatgaagta ggaagaggac cattagctgg acctgtcgtg
    17161 gcagctgcag ttatcttgcc gaaaaatgag atcatattag ggctgaatga ctccaaacaa
    17221 ttatcagaga aaaagcgaga acttctttat caacaagttc aagaaaaagc cctggcaatc
    17281 gggatcggga tcgttgatca gcagacaatc gatgatgtga atatttatga agcaagtaaa
    17341 ttagcgatga tccaagcagt agaaaaattg tccattgtac caagctattt gttgatcgat
    17401 gcgatgacct tggatttgcc tattcagcag gaaaaaataa tcaaagggga tgcacgatct
    17461 gtgtcgattg ctgctgcaag tatcattgct aaagtatatc gagaccaatt gatgaaagaa
    17521 tatgacgtgc tttatcctgg atatggtttc tcgcataatg caggttatgg aacaaaggaa
    17581 cacttagaag gacttgaacg acaaggaatt acgccaatcc atcgtaaaag ttttgcacct
    17641 gtaaaaaaat atttacaata aaaaacagcc gcttttacgt atcttattag aaagagagac
    17701 gaaaggcggt tttatgatgt atcaaataga agaaaattta ttgaaacttg cttatacaaa
    17761 aggaatcagt agtcaaggaa aatgggcact tgctaactgg atgatgcagt atccttataa
    17821 agaaatcgga tttgaagaca tcattaagat aggtaaaata accaaacacc gggagctgtt
    17881 tcgcaaaagt tggcaggaaa ttcacgctaa ctggggcaaa atccaatcga aacagtcgtt
    17941 tatcacttgc tttgatccca aatatccccc tcagctgctt cacttgacct atccgccaat
    18001 tgtactgttt tataatggtg atctatcttt actttcttgt aacatgttaa gcgttgttgg
    18061 tggaagacac acttctgctt tagccaaaaa aacagtttat tatttactaa aaccagtgat
    18121 agaagctgga tatgtgatcg tcagtggctg cgcgaaaggg atagatacat acggtcacca
    18181 agcagcaatc tctcatggtg gacggacaat cgcagtcatt ggaacaggga tagagcaagt
    18241 ctatcctgct gaaaatcgtg acttgcaaga ggtgattgca aatgatcatc ttcttttgag
    18301 tgaatatcct cctcaatccg gcccgaaaaa gcattgtttt ccaatgagaa atcggattat
    18361 cgcagctttg tctaaaggaa catgtgtctt tgaagccaag aaaaaaagcg gctctctgat
    18421 aacagcacag caagcattgg atcttggaag aacagttttt tctgttccag gaaatatttt
    18481 aacagaacat tctaccggat gtcatcattt gatccaagac ggtgcagttt gcacggtttc
    18541 gggtgaagat atcttggcag aatttaaaga ataacaccat acttttcatt tgcttttctt
    18601 gacaaacgtt ttctgaatgg atatgattag ctacgatttg tatgaatcct cttttaatag
    18661 taggaacacg acaatggaaa ggagtccatt cagtaatggc gtataaatat ttagtgattg
    18721 tagaatcacc tgcaaaagcc aagacaattg agaaatatct tggacgaaac tataaagtaa
    18781 tggccagtgt tggccatata agagatttac cgaaaagtaa aatgggtatc gattttgaaa
    18841 acaattatga accccattat atttctatac gcggaaaagg cgatgtcatc aaaagcctga
    18901 aagccgcagc aaaaaaagct caaaaagttt acttggcaag tgacccggat agagaaggag
    18961 aagcgattgc ttggcattta gcgtacctac ttgggttgga tctgaaagaa aaaaatcggg
    19021 tggtcttcaa tgaaatcaca aaagacgcag tcaaagcagc ttttaaggaa ccaagaacga
    19081 tcgatgtaga tttagtagat gcacagcaag ctcgtcgtac cttagacaga atcgttggtt
    19141 attcgatcag tcctattctc tggcgtaagg tcaagaaagg gttaagtgca ggacgtgtcc
    19201 aatctgtcgc tttaaaaatt attattgacc gtgaaaaaga gatccgagaa tttgttccag
    19261 aagaatattg gagcatcgac ggtaatttta aaaaagctcg caagaaattc aaagcaaatt
    19321 tctggggaat cgacggtaag aaaaagaaat taccagatgc acaaagtgta aaagaagtca
    19381 ctgctagaat tgatggaaca gacttcgaag ttaaaaaagt agaaaagaaa gagcgcaaaa
    19441 gaaaccctgc gaatcctttc actacaagta gcctgcaaca agaagctgcc cgtaagttaa
    19501 actttcgaac aagaaaaacc atgatggtag cacagcaatt atatgaagga atcactttgg
    19561 gtaaacaagg aacagtcggc ttgattacat acatgcgtac tgattctacc cggattgccg
    19621 atacagcaaa agcagaggcc gcagcattta ttgaagatac gtatggaaaa gaattttcta
    19681 gacatgatca ccgaaagatc aaaaatgctc aaggcgcaca agatgcccat gaagctgtgc
    19741 gtccaacgag tgtgcttcgt acaccagatg aactcaaaca atatttagat aaagatcaat
    19801 tgaaacttta tacattgatc tggtcacgtt ttgtggctag tcagatgaca ccagctattt
    19861 tagatacaat gaaagtgaca ttagaacaaa atggtgtcat cttcattgcg aacggttcaa
    19921 aaatcaaatt caaaggattc atgcaagtgt atgtggaagg tagagatgac ggcaaagaag
    19981 agaaagaaaa tattcttcca gaacttgaag aaggcgatgt agtccaatct gttgatattg
    20041 aaccaaaaca acattttact caaccaccag cacgttttag tgaggctacg ttgattcgtg
    20101 cactagaaga aaacggggta gggcgacctt ccacttatgc accaacactt gatacgatcc
    20161 aaagacgcta ctatgtaaaa ttgacacaaa aaagatttga gccgactgaa ctaggagaaa
    20221 ttgtcaattc attaatctgt gaattcttcc ctcaaatcgt cgatatccat ttcacagcag
    20281 aaatggaagg agatttggat aaaattgaag aaggcacgga agcgtgggtc aaagtggttg
    20341 atcgtttcta taaaccgttt gaaaaagaac tgacgaatgc ggaagaaaaa atcgaaaaaa
    20401 ttcaaatcaa agatgaacca gcaggattcg attgtgatgt ctgtggacat ccgatggtga
    20461 taaaattagg gaaatatggg aagttttatg cttgcagtaa ttttcctgat tgtcggaata
    20521 cgaaaccaat cgtaaaagaa atcggtgtga cttgcccagt atgtcatgaa ggacaagtca
    20581 ttgaacgaaa atctaagaaa aacagactat tctatggttg ttcccgtttc ccagaatgtg
    20641 aattcacttc ttgggataaa ccagtgggca gaaattgtcc aaaatgtgac ggatatctgg
    20701 tcgagaagaa agtcaaaggc ggtaaacaag tagtctgtgt aaatggagat tacgaagaag
    20761 acatccaaaa ataatagaaa agaggttctt tcattgaaaa tggtaaatgt tgttggagca
    20821 gggcttgccg gaagtgaagc tgcttggcag atcgcacaag caggagtccc tgtccgttta
    20881 tatgaaatgc gtccagtcaa atcgactgag gcgcatcaca caagtaattt tgctgaacta
    20941 gtatgttcca attcattaag aggaaacagt ttggctaatg cagtagggtt attgaaagaa
    21001 gaaatgcgcc gattgaattc ggtagtaatc acttcggcag atgaaacagc agtgccagct
    21061 ggtggtgcct tagctgttga ccgcgattct ttttctgaaa caattacccg aaaagtcaaa
    21121 gagcatccat tagtaacagt gataaacgaa gaaattactg aaataccgga aggaatcacc
    21181 gtagtagcaa caggaccttt gacttctcat ccattagcag aaagcatcaa agcattcaat
    21241 ggttcagatg gtttttattt ctatgatgca gctgcaccaa tcgtagacaa agctacgatc
    21301 gatatggata aagtatattt gaagtcccgc tatgacaaag gagaagcagc ttacttgaac
    21361 tgtccgatga cagaagagga attcaaagct ttccatgagg cactaatcaa tgccgaagtg
    21421 gcagaactta aatcttttga gaaagaaaaa tattttgaag gatgtatgcc aattgaagta
    21481 atggcacagc gaggattcaa aacgatgctt ttcggaccta tgaaaccagt tggattggaa
    21541 gatcctaaaa ctggcaaacg tccttatgct gttatccagc tgcgtcaaga caatgctgca
    21601 gcttctttat acaacatcgt gggctttcag actcacttga aatggggcga gcaaaaacgt
    21661 gttttccgga tgattcctgg gttagaaaat gctgaattcg ttcgctatgg tgtgatgcac
    21721 cgaaacagct ttatgaattc gccagaattg ctgaaaccga cttaccaatc aacgaaacgc
    21781 gaagatctgt tctttgcagg tcagatgact ggtgtagaag gctatgttga aagtgcagcg
    21841 agcggactac ttgctggaat caacgccgca cgcttagcaa aagaaatgga accagtcgag
    21901 tttccacaag aaacagctat tggaagtatg gcttactaca ttactcatgc ggaaggaaaa
    21961 catttccaac cgatgaatgc caactatggt ctgtttcctg aactgccaga gcgcattcga
    22021 gacaaaaaag caagatatga agcaattgca caacgagctt taaaagctaa tgaggcaata
    22081 aaaacagaat tagaaaaaac tgcaatccca aatgagtaag gaaactccat gaagagggtg
    22141 agacggatag tctcgctctt tttcttgcgt ttttcttaag aatttctcaa acaaaatgtg
    22201 aggaattgcg ccaattgtga acaaacttag aaatattggt taaattctga caatttattt
    22261 gtctttttat aaacgctgtg ctaaattatt ctctgggaca aaaggaaggt gagaaaatga
    22321 cagaagccac gtgggaacaa aaatttttgc gttatttgat tgtcgaaaga ggatattcag
    22381 aaaaaacgaa agaagcatat gaagaagaca ttctccattt caaacatttt ttggaggaat
    22441 ctggagacgc tgatctgctg aaggcggaat attttacggt tcgtgtctat ttgagtgcat
    22501 tagctgatca tcgtcctagc tatagcagaa attctatcag tcgcaagata gccagcctac
    22561 gttcgtttta tcagtatctt ctcaaagaag aagtgataaa agaaaatcca ttttcttacg
    22621 ttcatctcaa aaagaaaaat ttgagactgc cacgtttttt ttatgaaaat gaaatgcaag
    22681 cactttttga cagcgtagca ggagatagtc ctttggattt gaggaaccgc gctttactgg
    22741 aagtccttta cgggtcaggc atccgtttaa gtgagtgtag cagtttgtcg gtatcagaca
    22801 ttgattttga ttcagaggtc atgttgatcc atggtaaagg gaacaaagag agatatgctc
    22861 ctctaggttc ttttgctcaa gatgctctgc aagaatattt cagggaaggc cgccaggtat
    22921 tgatgacaaa atatcacgaa gagcatgata tcgtttttgt gaatcatcat ggaaaaccaa
    22981 tcacgcctac tggaattgaa tatgtcttga atcaaatgat caaaaaaagc agtttggata
    23041 gtgatatcca tcctcacatg ctgcgccata catttgctac tcatttatta aataatgggg
    23101 cagatttgcg gacagtccaa gaattgctag gacatgccaa tttatcgact acccagatct
    23161 atgcccatgt aacaaaagaa agtttacaaa aaaactatcg ttctttccat ccaagagcgt
    23221 aaaaataagg aaaagaacaa atttaggagg aaacaaacat ggtcgaatca ccatttcatt
    23281 caaccactat ctgtgccgtc gaaaaagacg ggaaatttgc tatggctgga gatggccaag
    23341 taacaatggg tgaatctgtt gtcatgaaag gcactgcaaa gaaagtacga cgtatctaca
    23401 atggagaagt tgttgtaggt ttcgccggaa gtgttgcaga tgcgtttact ttagaagaaa
    23461 aatttgaagg caaactaaac gaatataacg ggaatctaca acgcgcagct gtcgaattag
    23521 ctcaagaatg gcggacacag caatctatgc aaaaacttga agcgatgctg atcgtaatga
    23581 atgataaaga aatgcttctt gtttcaggta caggagaagt tatcacacca gatgatggta
    23641 tcttagctat cggatcagga gggaattttg cgttggctgc agcccgagca atgaaaaact
    23701 atgctcaaaa cgacatgagt gcgaaagaaa ttgcagaaaa tgcgttaaat attgccgcag
    23761 atatctgtat ctttactaat cataatatta tcgtagaaga actgtaagag gtgagtagat
    23821 atgtatgaat taaaacaaac accaagacaa atcgtaagtg aattagatga atatatcgta
    23881 ggacagcacg cagcaaaaaa atctgttgcc gttgctttgc gtaaccgcta tcgccgtttg
    23941 cagttagatg aaaaaatgca acaagatatt acaccaaaaa atatgctgat gatcggacct
    24001 acaggggtcg gtaaaacaga aatcgcacga cgtttggcaa aaatcgtcaa tgcaccattt
    24061 gtcaaagtcg aagcaacaaa atttactgaa gtcggttatg tcggaagaga tgtagaatca
    24121 atggttcggg atttagtaga aaatgcgatc caaatcgtag aaaaagagca gtacagccgt
    24181 gtatacacaa gtgctaaaaa aaatgcagaa aaacgtttgg taaaaatctt ggtacctggt
    24241 atcaaaaaag aacagaaaca atccactaat caatttgaac aaatgatgaa tctttttaat
    24301 gctagtcagc aaaataccgc tgaaccgcaa gaagaagtga cagaagatat tcgaatcaat
    24361 cgccgtacag tcttggaaca actacaaaag ggtttactgg atagtcgtga agtaaccatt
    24421 gaagttgaag accaaaagaa acctgcacca atgatgaaca atggattgga gcaaatgggg
    24481 atcgacctaa atgaaactct aggtgctttg acaccgaaga aaaaagtgga acggacggta
    24541 acagtcaaag aagctttaga gttattgatc aaggaagaat cagcaaaatt agtcaaggat
    24601 gctgatatcc atagtgaggc aatcaaatta gcggaagaaa gtggaattat ttttatcgat
    24661 gaaatcgata agatcacttc taaatcacag caatctggag aagtatccag agaaggcgtc
    24721 caaagagaca tattgccaat tgtcgaaggt tcacaagtaa acacaaaata cgggatcatc
    24781 caaacagatc acgtcctatt cattgcttca ggagctttcc atttgtctaa accaagtgat
    24841 ctaattccag aacttcaagg acgcttcccg atacgggtag aattagatga tttgacagct
    24901 gaagattttg tgaagattct gaccgaacca aataatgctt tagtaaaaca atacgtcgcg
    24961 ttgatcggta cagaaaatgt gtcagttacg tttacaaaag aagcaattga acggatcgct
    25021 caaatcgctt tcgatgtcaa ccgtgacaca gataatatcg gcgcacgcag actgcatacc
    25081 attttggaaa aactactaga agatctatta tttgaagcac cagatatgca aatgggagaa
    25141 ataacgatca cagaagcata tgtggatgac aaacttggct caattgcggc aaatgaagat
    25201 ttaagtcgct atattttata aaaaatcgga ggacgacaat gacagacttg ctaacgaaaa
    25261 cccgcaagat aaacacactt ttgcagcaaa agaatacttt tgacatgcaa gcagatttgc
    25321 cttacgataa aatggctgtc acactaggtg gtattcttga cagcaacacc tatatcatag
    25381 gaagtgacgg agtattacta ggttataatg aacgtcacga tgtgaacaat gaacgaatca
    25441 aaacaatgtt tgttgagaaa caatttcctg aatcttatac tgatacagtg gcacagttga
    25501 tgaaaactga agctaatatc ccaattacta gtgatattac tgcatttccg gtagagtcaa
    25561 gagagaaata tccatttggt ctgacgactg tcgttccgat ctttggagct ggcgaacgtt
    25621 tgggtacgat tatcttatct cgtatggaac aatcgtttgc agatgacgat ctagtcttag
    25681 cagaatatgg agctacggtt gtcggtatgc agatccttta tcagaagtct cgaagcatcg
    25741 aagcagatgt acggagtgca acggctgtcc aaatggcaat caacacatta tcttatagcg
    25801 aattgaaggc tgtacaagct atctttgaag cattggatgg agatgaaggt cgtctgactg
    25861 cttctaatat tgccgatagt atcggcatca ctcgttctgt gatcgtcaat gctttacgaa
    25921 aattggaatc agctggaatc attgaatctc gttcgttagg catgaaggga acttatttaa
    25981 aagtattgaa ttcccgtttt aaagacgagt tagcaaaaca cagttattag aagtaagggg
    26041 actggggcag atagaaatgt ttgttccagc cttcccattt taaaaagtaa gtcgaagttg
    26101 gaggaatggc aatgactgtt attattcaaa atgaccagct gatcgccgaa atcgctgaac
    26161 acggtgcgga attgatcagt ctgaaatcaa aagaacatgg tttagagtat atctggcaag
    26221 gtgatccagc gtattggggc agacatgcac cggttttatt cccttttgtt ggacgtttaa
    26281 aagatgatca gtatgtttat caagggaaaa catatcaaat ggggcaacac ggatttgctc
    26341 gggatatgga ttttgaagtc attgaacatg gacaagaaat ggctagtttc atcttaagga
    26401 gtacgccgga gacattagaa aagtatccat ttgattttga attagtgatc agctatgaat
    26461 taggaggaga cggcatcacg gttcattatc aagtggcaaa taccggtgaa aaagaaatgt
    26521 tcttttctat cggtggacat cctgctttca atgtacctct tgaagaagga ttgtcatttg
    26581 aagatttcta tctggcattt tctccattga aatcaagatt acgcctacca ttgaaaggcc
    26641 cattcatcga tatggatcaa aagacgttag gtcagacaaa tacgaatctg gctttgaatc
    26701 gtgaactttt tgagcaagat gccttggttt ttgaaacaag gggtctaaat gcgtacgcca
    26761 ttcgaagtga aaaatcttcc catagcgtaa ctttaagcta taaagatatg ccttatgtag
    26821 ggatctggtc tccttatcca aaagaagcgc ctttcgtttg tatcgaaccg tggtgcggaa
    26881 tcgctgacac ggtgaacagt agtggaaact tgatggaaaa agtagggatc aatcaactag
    26941 gtgcccatga aatcttcaag acaaaatatt ccatcacagt gaagtaagag gttgtgaccg
    27001 agaagttagc agggaacacc gtttaccaag gtgtgtaaaa aagctatcct gtaagtaata
    27061 agggagtgtg acatcgattt gtcacactcc cgttttatct ctttggaatg aaaaagtatc
    27121 aggatttttt cttgctgcta ttcaaaccaa acgggattcg actttcagta tggtttctga
    27181 tacgcttgat attgtcttta tgccgataaa agataaagga agaaactaaa aaggcaatga
    27241 tcgtcagtaa ccaattgggc ttagccaaaa tcacaggagc tacataagga aggacgatcg
    27301 tagataaagt gatcaatact gcactgatca tactgctcaa actcaccata cttgtacaaa
    27361 ataaactaac gataaagatg atacaagaat aaacaaaaaa tacaggatta aatcctaaaa
    27421 gcattcctgc acttgtcgca acagcttttc ctcctttgaa cccagcaaaa atcggaaatg
    27481 tatggccaag aatggcgcat accccaaacc aaagagggtt aatcccagaa aggtggaaga
    27541 tcatcggcaa acaagtagcc aatgtacctt ttaaaatatc cataagcagg acaacaatcc
    27601 cggctgtttt gcctaataca cgaaatgtat tggtcgttcc agtattaccg ctcccgtgtt
    27661 gtcggatatc ttttttgaaa aacaatttgc caatccagac accggaagga atagaaccta
    27721 aaagatatgc taaaataagt aataagatca atttcatttt ttaccctctt tcaagttgaa
    27781 aactatcctt tattttagca tgaataggta acaggaacaa ttgaaaaaat gaaagataca
    27841 agtataatag atggaataaa aagaaaagca aggggtggca gaaatgtctg taaaaaatcc
    27901 aacacaagaa acgattttca actatttgga agaagcaaaa aatattgccg tcgtaggctt
    27961 gagcaataaa ccagaacgaa caagttacat ggttgcacag gtattgcaag acaatggata
    28021 taaaatcata ccagtaaatc cattattggc tggtgaagaa attctaggcg agaaagtcta
    28081 tgcgaatttg acagaaatcg atgatccaat cgatatcgta gatgtattta gacggagtga
    28141 atttttacct gaaatagcag gtgatttttt gaaaactgat gctaaagtgt tctgggcaca
    28201 attagggatt gaaaacaaag aagcagctga gatgctaaga aaagcaggac gtacagatat
    28261 cgtaatggat cgttgtatta agattgaact tggtaagttg aaagaaaacc aaaaataaaa
    28321 atgaccacaa agaagagatg atcgatagag gggaatgtcg aaaaagcggt taggagataa
    28381 ttaaaattga tttctcgtct accctctttt ttttcacgac cttttctagt atgataatcg
    28441 tggtgcggtt ttgccgcaaa gtattattga aggagcgttt gccttggcaa aaaaagtaaa
    28501 caacgaatac aatgactcgt ccatccaagt attggaagga ttagaggcag ttagaaaaag
    28561 accagggatg tacattggat ccactgacag ccgaggcttg catcatttag tctatgaaat
    28621 cgtcgataat gcagttgacg aagcattatc aggttatggc agtgagattg atgtgaccat
    28681 ccatgaagac aatagtataa ctgttgcaga tagcggacgt gggatgcctg taggaatgca
    28741 tgcttccgga ataccaacag ttgaagtgat ttttactgtg ctgcatgctg gcggaaagtt
    28801 tggtcaagga gggtacaaaa cttctggtgg actgcacggt gtaggagcca gtgtggtaaa
    28861 tgccttatcg aaatggctaa ttgtaacgat cgttagagat ggcgtagagt atcagcagaa
    28921 atttaaaaac ggcggtaaac ctgacggtac tttgaaaaag ataggaaaaa caaaaaaagc
    28981 aaacgggacg actgtccatt ttttaccaga tgatacaata ttcagtacaa cgaaattttc
    29041 atatgaaatt ttagccgaac ggttaagaga atctgccttt cttctaaaag gcgttaaaat
    29101 ctctctttct gatcttcgtg gagaagaacc agtcaaggaa atttttcatt acgaagaagg
    29161 aatcaaagaa tttgttgatt atctgaatga agaaaaagat acattgacac cagttgttta
    29221 tttttcagga gaaaaagaag gtatcgaagt agaggtcgct tatcaataca atgacggtta
    29281 ttcagaaaat gttttatctt ttgtcaataa cgttcggaca aaagatgggg gaacccatga
    29341 agctggtatg aaagcggcga tgacgaaatc ttataatgaa tatgcgagaa aagttggttt
    29401 gctgaaagaa cgggacaaga atctggaagg tagtgatttc agagaagggt tagctgctgt
    29461 actttctatc cgtgtacctg aaaatcttct gcaatttgaa gggcaaacaa aagaaaaact
    29521 tggtacgcca gttgctcgta ccgtagtaga taacgtcatc agtgaacaaa tgggctttta
    29581 tttgcaggaa aatagcgaaa tgagccagat gttggtccgt aaagcaatca aagccagaga
    29641 agcgagagaa gcagcacgta aagccagaga agaaagccga aatgggaaga agcgtaaaaa
    29701 aggcgaatct cttctttcag gaaaattgac acccgcacaa tcccgaaacc ctaagaaaaa
    29761 tgaattgtat ttagtcgaag gggattctgc tggcggatct gctaaacaag gaagagacag
    29821 aaagttccaa gcaattctac ctttacgagg aaaagtcatc aataccgaaa aagctaaaat
    29881 gcaagatatc ttgaaaaatg aagaaatcaa tacgatgatc tatacgattg gtgcaggagt
    29941 cggtcctgag ttttctatcg aagactgtaa ttacgacaaa gtaatcatca tgaccgatgc
    30001 ggatacagac ggcgcccata ttcaagtatt actgcttact ttcttttatc gttatatgaa
    30061 accgctgatt gaagctggga aagtatatat cgcgttaccg cctttatata aagtatccaa
    30121 aggacaagga aagaagcaag tcattgaata tgcgtggaca gatgacgaat tggcagcaat
    30181 gattaaaaaa gtcggcaaag gatatatgct gcagcgatat aaaggacttg gagagatgaa
    30241 tgcggaacaa ttgtgggaaa caacgatgga tccgacttcc cgtacgttga tccgcgtccg
    30301 tatcgatgat gctgcgcaag ctgaacgtcg agtaaccaca ctgatgggtg acaaagtaga
    30361 acctcgaaga aaatggatcg aaaatcacgt gcaatttacg ctcgaagaag atggcagtat
    30421 cttagataaa aaagaggata ctgaaatctc tccttcagtt tctaatgatt tattagatga
    30481 agaacgagca gataaaaatg aaaacaatca gttatttgaa gtagaatagg aggtcacctg
    30541 atggaaaatc gacaagaagt acaagaatta actttagaag aagtgatggg tgaccgcttc
    30601 ggacgttatt ccaaatatat tatccaagaa cgtgcactgc ctgatatccg tgatggattg
    30661 aagccagtgc aacgccggat attatttgcc atgaacaaag atggcaatac gtatgacaaa
    30721 ggattccgta aatcagcaaa atctgtcgga aatatcatgg ggaattatca tcctcatggt
    30781 gacatcagta tttatgaagc gatggtccgc atgagccaag actggaagtt gcgggaagta
    30841 ctgatcgaaa tgcacgggaa taacgggagt atggacggtg atccacctgc tgcgatgcgt
    30901 tatactgaag ccagattatc caagttaagt ggagagatgc tagcagatat cgagaaagaa
    30961 acagtcgatc tcgtgtggaa ttttgatgat acagaaaaag aaccaacagt ccttccagct
    31021 cgatacccaa accttctcgt caatggatcg acaggtatat ctgctggata tgcaacagaa
    31081 atcccgactc ataacttagc tgaagtgatc gatggcacaa tctatatgat cgatcatcca
    31141 caagcgagcc ttgaaaaatt gatggaatat attcctggac ctgactttcc aacaggaggg
    31201 atcttgcaag gaaaagatga aatcaaaaaa gcttatgaaa caggacgagg aaaagttatt
    31261 cttcgttcga aaacaaagat agaggcaatg aagggtaata aacagcaaat cgtgatcaca
    31321 gaaatcccat atgaagtaaa taaagcgacc ttggtgaaaa aaatggatga gatccgtttg
    31381 aataagaaaa tcgatggaat agctgaagta cgagatgaaa gtgatagaac aggtctgcaa
    31441 attgtcgtcg aattgaaaaa agacgccaat gctcaaggaa ttttgaatta tttgttcaaa
    31501 aacactgagc tacagatcaa ttacaatttc aatatggtcg ctatcgacca tatgactccg
    31561 catcaagttg gactgaaaga cattttaaga agttatatcg agcatcgaaa gcaagtcata
    31621 acaaaacgta gtcaattcga tttagccaaa gctcaaaaaa gacagcatat cgtagaagga
    31681 ttgatgaaag ctttatcgat tctggatgaa gtaatcgcaa cgattcgtga aagtaaagac
    31741 aaaaaagacg ccaaaaagaa tttagtcgac gtctttcaat ttacagaaga acaagcagaa
    31801 gcaattgtca cattgcaatt ataccgtttg acgaacacgg atatcacaga gcttcaaaag
    31861 gaatccgaaa gcttgattgc gcaaatcaca gagttgaata aaatcctttc aaatgacaaa
    31921 gagcttttct ctgttatgaa aaaagaattg cgagaagtga aaaaaaatta ttcttccgct
    31981 cgtctaacga caatcgaaga cgaaatcgaa gaaatcaaaa ttgatacgca agtcttagtg
    32041 gcacaagaag acgtaattgt cagtgtgacg cgagaaggct atgtgaagcg aacaagcctt
    32101 cgttcttata gtgcttccaa accagaagaa atcgggatgc gagaaggcga ctacttgcta
    32161 tactcaggtg aattgagtac attggaccat gttcttctga tcacaaataa agcaaatgtg
    32221 atctaccgcc ctgtccatga actacccgat ttgaaatgga aagatgctgg tgagcacatt
    32281 tctcaaacaa tctccaatct gtctgtagac gaatcgattt tagctgtttt cccatatcaa
    32341 aaaattcaag cagagaaaac atttgtattc atcagcaaga atggattgat caagcaaaca
    32401 cgaatgacag agttcgaacc atggcgcacc tataagagcc gtccgctcag ctgtatgaag
    32461 ctaaaggcgg aagaagatga actgattgct gtgtatctga aagaagatca gccaggctta
    32521 gatgttttct tagtaacgca tcaaggaatg ggtttgcgct atcctttaac agatgttccc
    32581 gttgttggag caaaggcagc tggagtgaag tctatgaatt tgaaagatgg agataggatt
    32641 atcaacgggc tgcttgtgtt agcagaaggt gatacgccga tcgtaatcgt tactcagcga
    32701 ggagctgtta aacgcatgct tgctcaagaa atcagccaaa cttcacgtgc gaagcgggga
    32761 gtgacggtca tgcgtgagct gaaaaaaaat ccgcaccgta ttatctatat gtcggaagga
    32821 agatcaaaag aaataacctt gatgaatcaa aaagggcagc agttaacgat tgacccaact
    32881 gatttcccta taggtgatcg aacatcgaat ggatcatttg cgatggatga gaaaaaaggt
    32941 ggagaagtca tcgaagttat cgatgctcct gagattttca tcgagtcgta actgttgtag
    33001 tattttaatg aagagacgcc atctgtatta atacaggtgg cgtctctttt tcattcattt
    33061 ttaataaatc cttatacgtt tgcaaaaaaa gatgaaagtg ttcacaatgc ttaaatgttg
    33121 gtatgtcaac gttgatttaa atatatgtaa ataaaacata aaaattgtta aataaaaaac
    33181 aagaaaaccc ttgcaaagat agggtgctgt gttatactaa tcacgtaaaa actgttacat
    33241 aaaacagaaa tttaggaggt ccatacaatg gagcaatgga atggatttaa aggtaccaaa
    33301 tggaaagaag gcgtagacac tagagacttt attcaaaata actacactga atatcgcggt
    33361 gatgacagct ttttggaagg cccaacagaa gcaacagaaa aattatggga tgaattgcaa
    33421 aagttaaatg atatccaatt cgagcgtaac ggtgtctatg atatggacac agaaatcgta
    33481 tcaactatta cttcacacga tgcaggctat ttggataaag atttggaaaa aatcgtcggt
    33541 ctacagacag acaaaccttt gaaacaagca ttcatgccgt tcggcggaat caatatggct
    33601 aacaatgcgc taaaaagcaa tggctataca ccaaacgatg aattgacaca tattttcact
    33661 gactggcgca aaacacataa tcaaggtgta tttgacgctt atactgctga aatgcgtgct
    33721 gctcgtaaaa acaaaatcat tacagggctt ccagacgctt acggtcgcgg acgtatcatc
    33781 ggtgactatc gtcgtgtggc attgtatgga atcgactatt tgatggaaca aaagaaaaaa
    33841 gatcatgata tgactggtta tcatacaatg agtgaagaag tgattcgttt acgtgaagaa
    33901 atcactgaac aatatcgtgc attagcgcaa atgaaagaaa tggctgcgaa atatggctat
    33961 gatatttcta aaccagctgc aaatgcaaaa gaagctgtcc aatggctata cttcggatat
    34021 ttagcagcaa tcaaatcaca aaatggtgct gcgatgtcaa tcggacgtat ctcagcattc
    34081 cttgatatct atatccaacg tgatttggat aatggagtaa tcacagaaaa agaagcacaa
    34141 gaattgatcg accacttagt aatgaaatta cgtatggtca aattcgcgcg tacacctgaa
    34201 tataaccaat tattctcagg attccctatc tgggctactt tatccattgc aggtatggga
    34261 ttagatggtc gttcattagt tacaaagaat gatttccgtc tgcttcatac attaacaaat
    34321 atgggacctt caccagaacc aaacttgact gttttgtatt ctgaacacct tccagaagga
    34381 ttcagaacat atgctagcag aatcgctatc gaaagttctt cgattcaatt cgaaaatgat
    34441 aatcagcttc gtgaacaatg gggttctgat gattgtgcga ttgcttgctg tgtatcagga
    34501 acagttgtcg gaaaagacat gcaattcttt ggcgctcgtg ctaacttggc taaaacacta
    34561 ttatatgcca tcaatggcgg agtcgatgaa gtgactggcg cccaagttgg accagaatat
    34621 cgtccaatca catcagaaat actagacttt gaagaagtga aacataactt catgaatatg
    34681 atggattggt tagcagaact atatgtcaat acgttgaaca tcattcatta tatgcatgat
    34741 aaatattctt atgaagcagc tcagctggct ttgatggatt ctgacttgca acgcacattt
    34801 gctacaggta ttgctgggat ctctcatgcg gcagacagct tgtcagcgat caaatatgca
    34861 aaagtaaaag caatccgtaa tgaaaaagga atagcagttg attttgaagt ggatggcgac
    34921 ttccctaaat acggaaatga tgatgaccgt gcagatgaat tagtttcatg gatcttggaa
    34981 tacttcatgg gacaaatcaa acgtcataaa acttaccgca actcaaaacc aacaacttca
    35041 ttattgacga ttacttcaaa tgttgtttac ggtaaaaata caggaaatac tcctgatggc
    35101 cgtgaagctg gaaaaccact tgcgccagga gcaaatccaa gttacaatgc ggaacaaagt
    35161 gggttattag ctagcctgaa ctcaacagct aaaatgaatt acggctgtgc attggatgga
    35221 atttcaaata cccaaacaat caatccttca ggtcttggaa aagaacaaga tacaagaatc
    35281 gaaaacttgc gtaatgtctt agatggatac ttctcaaaag gagcttatca tttgaatgtc
    35341 aatgtattca gtaatgattt attgcgtgat gcaatggaaa atccaatgaa atatccgaac
    35401 ttgacgatcc gggtatctgg ttatgcagtt aaattccgtg acttgacaag agaacaacaa
    35461 ttagatgtct tgatgagaac ttcacacgac agaatgtaaa aagttcgtga aaaaagtttt
    35521 tcgacttagc gtcgaaagga cgttgaatag ccatcgcatc aaaatcgaat aatcagtatg
    35581 cttatttgaa agaaacgatt tacaggggca ggacttgtat gttccgtccc tgtaaatttt
    35641 acacataacg aagcggcaat tgcgaaaaat tttgttcaga aagcttcgct tcgacagcta
    35701 acttgtactt aaaatgaaat caaagaaaag atgtgaactt aaatggaaga aaaaacaatc
    35761 ggctatgttc attctatcga aactttcggt tcagtagacg gacctggact gcgctttgtc
    35821 gtgtttatgc aaggatgccg catgcgttgc caattttgtc acaatccaga tacttggaat
    35881 attggcggag ggaaagaata cacagcagat gaacttttag ataaagcaga acgcttcaga
    35941 ccttactggg gagataaagg tggtattact gttagtggtg gagaacctct attgcagatc
    36001 gattttttga tcgaactatt taaaaaagca aaagagcgga agatgcatac tacattggat
    36061 acatgcggaa aaccttttac gtatgaagaa cctttctttt cacgttttca agaattgatg
    36121 aagtatacag atttactgtt atttgacatc aaacacatcg ataatgaaga gcataaaaaa
    36181 ctaacgcatt gggacaatga aaatatttta gaaatggctc aatatttgtc aaaaatcaac
    36241 aaaccggttt ggattcgcca tgtactagtt cctgagcgaa gtgattatga tgaatatttg
    36301 atccgactag acaactttat tcaaaccttg tcaaatgtag acagagtaga gattcttcct
    36361 tatcatacga tgggaaaata caagtgggaa acacttggtt tgaaatatcc attagaaggg
    36421 atcgaaccac ctacaaaaga acgtgtcgaa aatgctaaac gattgcttca tacagaagag
    36481 tatacaaaat atttaacgcg ataggtcgca tcggaaagaa gataagtatt gcttctttcc
    36541 gtttttttgc tattattaaa taggagaaat cacaaaggag cgaatgacat gtcaaaaatt
    36601 ttagtttttg gtcaccaaaa tccagataca gatgcaatcg gggcagccat tgcgttttca
    36661 cacttgcaaa atgaattagg taaagaaaca gaagcagttg ctctaggtac acctaatgaa
    36721 gaaacacaat acgcattaga ccactttcag ctatctgcac cacgagtagt agagtcagct
    36781 aaagcagaaa atgcagatgt catgcttgtg gatcataatg aattccaaca aagtatttca
    36841 gatatcagcg aagtaaatat tttagctgta gtagaccacc atcgtattgc aaactttgaa
    36901 acagctaatc cattgtacta tcgtgcagaa ccagttggat gtacaagtac gattatttta
    36961 aaactatata aagaaaacca agtaacaatt cctaaagaaa tcgcaggaat catgctctca
    37021 gctatcattt cagatacatt gttgttcaaa tcaccaacat gtacgcctga agatgaagca
    37081 gctgcaaaag aacttgcagc aatcgctgaa gtcgatctaa acacttatgg acttgaaatg
    37141 ttgaaagcag gaacaaatct aagtgataaa tcagctgcgg ttcttcttga tttggatgca
    37201 aaaagtttcc caatgggcag ttccaacgtt cgtatcgctc aagtcaatac agtggacctt
    37261 aatgaagtga tggatcgaca agcagagcta gaagcagcaa tggaagatga aatgaaagca
    37321 aatggctacg atctgttcgt attagttgtc acaaacatct tagacagtga ttcagaatta
    37381 cttgttgctg gtaaaggaaa agaaaaagta gaagaagctt tccaaacaac tttgaccaac
    37441 aaccgtgctt tgcttaaagg tgtcgtttca cgtaaaaaac aagtcgtacc tcaattgacg
    37501 gctgtattta gctaatcaaa tggtagtatg aagcattcaa aatgaatgga taagcgattg
    37561 atataaaaag aaacatagaa catactaaag gccgaagaaa tggaggagaa taacagtcaa
    37621 ttatgactct tgttcttcct cctttttacg taaaagcctt ttaagtaaaa taaaacggat
    37681 agaaaagaga acatatatga actattattc aaaaaataag gaaaactttt atcaaaaact
    37741 gaccgatgat ccgctttttt cttcattgac cgattatcta tatgaacatc gagaacaaga
    37801 aacgattcta agagaattga aaaaagaatt ttcgcaaaat aaattttccc attttcttga
    37861 tttattgatc gatgcaggat taatcaagag ggaagaacga agatatcatt tgaactttcc
    37921 aatatttgat cctaaagatt acttgcaaca agccacttcg gctgctgaaa ccatagctga
    37981 acaattgaag agactctctg ttgatgaaca aaaattagcg atgggagaag ttatttgggc
    38041 gtattgtttc gaagatgaac ggaaagaagc gtatttttat ggagtaagaa acagccgaga
    38101 gacagaattg ctgaggacaa ctgcaggaaa tgagaagtac cgttttatca cactttcctc
    38161 tatagaacac ttcccgctta ctttggctaa ttactttttt gtacagaaga atcagcttcc
    38221 tgtaacgaag gcattcaaag aattagccga acttattgga gacgtaaatg aatcgtactt
    38281 ttttgatcaa atagaagtta tcgttgacag gatacgtaag aataaatata aaaatcgccg
    38341 gcctagtatt ttccatcagt ctctacttgt gacgaatact ataaaggaag aagaatcatt
    38401 cacattagaa ttacctattg tcgaaaaaaa caattttgag attgaattac caacattgga
    38461 tccttcattg acaatggagg aaatggcctt tcttaaacga caaatctttt ctgagctgag
    38521 caagaaattt ataccgcatg cattttctta tatcaaagaa tatggaacag ttttagtgag
    38581 taaaacctaa gagagcagta agcaaaaatt atactgactc ttgcaggagg agcctttctc
    38641 ttcctttatg gttaaaagaa ttatttgagt attttgccta tctaccacct attagattca
    38701 ctacatggtc tggaaacaaa ggaatgcaaa aaaatggtga gaaatgtgga atgacaaagg
    38761 aagtagtgat aagaaaagtt agatttttaa ataatcaata ttatgattca gtcaagtatg
    38821 gcattttatg ggaagaacta gctgattaga ttaggaagtc catttgataa tccagaatca
    38881 ctaagaaacg aatggcgagt cattaataat ttatccaatc ttgggttatt cttttagatt
    38941 gaagtgttta aaactaaaaa agcatttatg aagtcgtaat agtcaggctt caaaatgctt
    39001 tttattttgt ttgttttttc tttgccacat aaatacacct agactgacga tgaagagcat
    39061 atccaacaga tttcctgcga cttggatcgt cgaagggttg gtcagtggca ttaaagcaag
    39121 gacaaaaaag gaaaacaagc tgtaaataaa acaggtgaca ggaactaatc gaaagaagag
    39181 cggacatttc aattggctaa aaatgagtga aaaaataaaa taagtaaaaa tggataaaat
    39241 cacgactaaa ccattcatga taaagaagaa aagcgtattg tgattaaacg aataaaaaag
    39301 aattgctaaa aaagaaaacg ttttaaatgc aatcaatacg cttgaagctt cgtttaacgt
    39361 accaggatgt cgatgaaaaa aataggcacc gaaataaaca gaaaacagta agccgcaaag
    39421 agaagacaaa atcaaaaaaa acggattttc ttcggcttct gtgatatcag aatgatccaa
    39481 aagcaaccag cctaatgcac tagaaggcgc atgtgaggtc ttaaggtatg aataacatag
    39541 aaaaaataag atcgtcaaag ttgcaaaaaa agagcctaaa tgtaaaaaat tagtggttct
    39601 acgttgaatt tccataatat ctccaaatta aattgataag tatataaagt ataataacaa
    39661 attgatgagt atatgtcgat gttttttaat caaaataata aataaaaact gtctaacatt
    39721 taaaatttaa tttagatatt agacagtttt taagtttgtg agttattttc cttgtcgttt
    39781 tctcactttt ttagtccaga aaccacctga aatatatttt ggctcataag aaatgataaa
    39841 agcacgctct tcgatttctt tgatcaggcg atacagttca cgttcgcttt ttctaggaga
    39901 aagtatttcg agaactagcc gctcaccttc cagccccatt gcagaagtct gtgtcacacc
    39961 ataaccgtgt tctctcagta tacccggcaa acttttatct tctgcgctat ttgctggcaa
    40021 aatcgttgtg accatgatgt atcctaatgc caatttgtct tcaatcaaaa ttccgacact
    40081 gatacctact gcgtaaccta acgcatagac aaataaattc agtggattat ctaaacgatc
    40141 taaaacaagg gataagccga cgatataaat cgtgatctcg accatactga caagtggagc
    40201 aatcagtcga tagcctttca ttgtcaacat gaaacgtaac gtgttcagag tgatataagc
    40261 aaaattaatg aggaagatca tccccaacat ttttggatca atcatttgta aaactccttt
    40321 catttatata acaacaatat caaaaaaaat cgtaagtgaa gaaaaattga aactttatac
    40381 atacaaaaaa atgataaaat gattataata gaattataaa gataggttag gtgattaaaa
    40441 tgaaaacggt caatcgtgtg ttttgtgcca gccacgtgct aagtctcctt ctcagtatat
    40501 acttaggtgt ctattcgatt caacagccaa ttgaggtaga gaacattgtt tttcagatgt
    40561 cgctgacaga tggtttaatt ttaagcgttt ttttcttttt gatactgttt attggtaata
    40621 ttttcggtag cgttgccagt tttttgaatt tttctattta tccactcctt tcgctagcat
    40681 taggagtggt gggactttgt tctctgtgct tatttcccga gccattcagt cctgcattta
    40741 tattatttgg tacactgaac ctgttccaga caactgttgg agcatggttg ctatggcgat
    40801 caggaaattt aatgaaaata ggtgagtaac aattgaatcc aattatattg aaacgttctg
    40861 tccatcatat tccagtgtta gaagttgttc tgaaagaatt aagagaggaa cgtattcccg
    40921 ttgtcatcta ttatcacgga tggcagacaa gtaaggagtt agttttgacg caaggaagaa
    40981 aaattgcgca gcagggcatt cgtgtgatcc tgccagatgc gatgaatcat ggggagcgca
    41041 aacagccggt ttcttctatt ccatcctata cattttggga tagtatctac ggaaatctgt
    41101 ttgaatttga cacacttatc aagcatttag aaaaaagagg tcttctacat gatcagcttg
    41161 cagttggcgg ggtttcgatg gggggaatga caacatgcgc cttgttggct aaacatcctc
    41221 atatagtagc gggcgtgtgt ttgatgggtt cccctgcacc tttggaatat ggaaaagaaa
    41281 tcgtaaggcg cgcatcggaa tataattatg tcgtaccaaa agactatttt gatttgattt
    41341 catgggttaa gagctatgat ttgtcattgc agccggaaaa gttagctgga cgtcctctgt
    41401 tcttttggca tggacaagct gacgaaaaaa tcccttatat acaaacggaa cgatttgtag
    41461 aaaaaaatcg gcataagtct tacggaaaag aaattgtttt tcgttcctca aaaacacagc
    41521 gacatatggt acaaatacca ctaatggaag aagcttccac ttttttagca aaaaatttga
    41581 taaaaaagta taaataattg aaacggaaaa tcactcatga cgatagagga ttttccgttt
    41641 tttattttgg gctataataa actctgttag gaaaatttgg tataattgat agtaagaatg
    41701 acaacatgtt agaaaggaag agagcatgcc cactttagca gatgttgcaa aacgtgccaa
    41761 tgtttcaaaa atgacggtct ctcgagtcat caatcatccg gaacaggtga ctgacgaatt
    41821 gaaagagtta gttttctcag caatggctga actggattac cgtccaaata ttgctgcaaa
    41881 agcacttgtc acgaatcggt cgcagatcat caaattattt atactggaag aaatcgacac
    41941 aactgagccc tattacatga atttgctgat gggaatcgct aaacggatcg gtaaagcgca
    42001 ttattctctc caattagtta caaatgatgc cttcgacgtc ggttcttgtg atggatacat
    42061 catcacaggt gtcagaaaaa aagacttcga ttggatcgac cgtttggaaa aaccagttgt
    42121 cttgtttggg gaaaattctg aaggatatga ttatgtagac agcgataatg aatatggtac
    42181 agcaaaagca acgcaatatg ccttagaaag agattatcaa acgattattt atatcggtat
    42241 cgaagtggac gagccttttg aaatttcaag ggaaactggt tatttatctg tgatgaagga
    42301 agttgatctt cctagtaaaa tcttgcggtt tccaaatcat tcgacagaag tagaaagata
    42361 tatgacagaa aactgggcag attttacaga taaaacttgt tttgtatgta gttcagatcg
    42421 gctagcacta ggagcagtaa gagggattat aaatgctgga ggacacttgc ccgaagaatt
    42481 tggtgtgatt ggatttgatg gggtattttt agaccaaatc agttcaccta aattgacaac
    42541 gatcaagcaa gatattatac gtatgggtga agtatgtgga gaaatgttgt taaaaaaaat
    42601 agaagaaaaa ggggcgagtc aaggttatcg tcgttttttt cctgaactag ttatcagaga
    42661 gacaacgaat taagtcttat tactatatat atatttatga aattcatcgc tattttctta
    42721 aaataatcag cgcattgcta ctgaaaacaa tgaatctgtg ctattattga gaaaagttcc
    42781 atttttgaga aggatggttt gaatgaaaga aatcagacga aaacatttcc gttttcctgc
    42841 gtacgatgat gagttaggcg taaaattaac caacgacaag aagcgagtat tatttgacgg
    42901 acaagaagat cttttgactg aacagaatca gtccccgttt gaacagatga aagaatttca
    42961 tttcacgaac acgaacaccg agaaaatccg tcgcaagcgt cgtgcaacaa atggattgaa
    43021 gtcagctccg cgtaaggaaa atttggaaaa gcataaagga aaattaccgg attataccgg
    43081 ccattaccaa tcagaaatca catcgacagg acgaaaaaaa ctttttggtg attcctctcg
    43141 ttctgtcaga caaagtgaaa caaggacaga gtccaagcat actacacgaa acgcatctgt
    43201 tgacacgaag gtgcgggagc gttcttattt tgttcctaaa tatgtacccg catcgattat
    43261 cccagaccct agagaaagca aaatttctga ggatcattta atcgaatcga tgaaaaaaac
    43321 ggatgactct tatctgttgt tcgatacaga accgacgccg tatcaagaaa aaagaaatgg
    43381 tgagccgtct gtacgaacat tcaatcgaac aaaaacgtta gaggaaacaa agcagtcaga
    43441 agaaaaaaaa tcgaaaaaaa gccatggtat cttagaacgc tcattacaag gattgatcga
    43501 tgatcaagga aactctttgg gagaaaatag ctattttaaa taagtgatat acaaatttat
    43561 attcggctac agttggaaag gaaacgctgc ggcgtttcct tattttatac tctatccgaa
    43621 agtttatatc gtatcctcaa atttttttga gtttaagcga attttttctc ccaataagta
    43681 agaaaataat ggcaaaataa aaaaacaaac tattttcgca gatcgtttgc aaaaatagtt
    43741 tattttttta taaagaagat tttactgaat aatatcattt tagtttacat aatgatattt
    43801 ctgtaaatta aataaagtag tgaaaaataa gaatcagtgc tctaactgtt caagaggatc
    43861 aagtggttca aatgtttctg tagtctgttt tgcttccaat tggggcaaaa cagatccaat
    43921 ttccagatac ttcactttat tcaatgtata agatagaata gaacagctaa gtaatgtata
    43981 cagaaaatgt gtgagatcca aataaagcaa ggagacaact aaaataccaa aagtaatcaa
    44041 gaaaagactt ttgccaatct taatatgaaa atatttttca atggcttgat aaatgatatc
    44101 tgttccgcct gtgcttccgc cgaatcgaaa gacgagaccg caaccaatgc cagaaagaat
    44161 acctgtcatc aaactattga tcagtagact atctacagca aaatgtatat gaaggctctc
    44221 ccataaatgt aaaaagaaaa ctagcgcaaa tgttccgacg atcgtccgga gaaaagcgtg
    44281 ttttccaaaa agaaacaatg agataagcaa taaaggtaaa ttaaaaagca gtgaagtgac
    44341 agaaggagcg aatccaaaaa gattatgcaa aagcaaagca ataccagtaa ccccaccatc
    44401 tgccagctta gatggaatat tgattcctgt cacagctaat ccgtagattc ctgcgcctaa
    44461 aatgattccg cacaattctg taaataaatt taattttttc atttctagcc tcttttcttt
    44521 tgaaaatttt cagcaacttc tttattatac tgacttatac tcttacttca agaggaaaat
    44581 gaaaaaaaat tatttttggc tgtttctttt tatttatcaa ataaggagtg gaaaaatgcg
    44641 agcagcagac ttattgacaa ttcttacaaa atcacccaaa aaaacagagt atcaaggagt
    44701 ttttttggct caagaacaaa aactggtgcc tgtgacaatg gtccagataa ataaagcaaa
    44761 tcaatttatc tttttatttg aacacggcaa agcaccactt gctatgaaag acatctttct
    44821 ttttttgatg aagaaccgtg agaaagctgt ttattatcag tcaaaagaag aactcattcc
    44881 tctttatgga gtgaaagaga tagaaaataa agtggtgata taagtaaaaa taagaaaaca
    44941 agacgtttat gatgtcaaaa caaccatttt ttacattttt ggcaaaaaag tgtcatgata
    45001 cagtataata ttcgttgaac aggccaataa aggtgttctc ccccacgaga tttctacttt
    45061 attggctgtt tctttttatt aaaataaaag ttgtgtgtgt aaaaaagata tagctgattc
    45121 caagtgacaa tttcgtatag atttttatgg tattcgtagt gaaaaaacga gaaccaaaaa
    45181 gttgatccga ctttgttgct tggattcttt ttttgtcagc atatttagag gtattttttt
    45241 cttttttttg ttcgtgctgt aaggttaagg caagacaagt tagttgggaa aaaggaaaga
    45301 aatgtttata cttaaagaat aacagaaagg aaggtcgcat gaataatttt atacaaacat
    45361 taagtgaaag aaaaggcgag ttgctggaag ctgcatttca acatctgtcc atttctctca
    45421 tttctttgct gattgcagca ctgattgcta ttcctttagc gatttgggca gccaatcata
    45481 aaaaaatggc agaagtctta ttgcagatca cgggtgtgct ccaaacgatt ccttcacttg
    45541 ccttattagg tttacttatc ccatttgtag ggatcggaac tgttccagca ttgattgcac
    45601 ttgttattta cgctttgctt ccgattttcc aaaacacgta tattggtcta gctgaaattg
    45661 acccgtctat tgaagaagca gcggtagcat ttggtatgtc cagaatgaga cgcttgctga
    45721 aagtagagct tcccatcgca ttacctgtca ttatctcagg tatccgaact gccttagttt
    45781 taatcatcgg tacggctact ttggcagcat tgatcggagc aggtggatta gggacattta
    45841 ttttgttagg tattgaccga aatacacctg ttttgacatt gattggtgcg atcagttctg
    45901 ccttgcttgc aattatattc agcggactga ttcgctggtt gcagcataag aaacctcgat
    45961 attccatcat tactttagca gcagtggtgt gtttatttgg cggcgtttct ttatatcagt
    46021 ctgccttgtt taaaaatgaa accatcacga ttgctggaaa attaggagcg gaacctgaaa
    46081 tcctgatcca aatgtataaa gaattgattg aagacaacac aaaaacagaa gttgaattaa
    46141 aaccgaattt tggcaagacg agttttttgt tcaatgcact ggatcaaggt caaatcgata
    46201 tctatcctga gttcacaggt actgtcctag aaagcttggt gaaggtacct gaagcaatga
    46261 aaagtgctga tttgacaaaa gaaaaaacat atgacgaagc agaagaatta ttgaataagc
    46321 aattcgatat gacattatta aaaccaatgg cttaccaaaa tacgtatgcc ttggcagtca
    46381 agagatcttt tgcgaacgaa catcaactta aaaagatttc cgatttggca gctatctctg
    46441 atcagatcaa agcgggattc acactggaat ttattgatcg ttcagatgga tataaaggaa
    46501 tccaagaagc atatggcttg aatttttcaa gtgtacaaag catggagcca agtttgcgtt
    46561 accaagcaat caataatgga gatgtcaata ttgtggatgc ctattccaca gatagccagc
    46621 tcaaggagta cgatctagtg actctagaag atgatcgagg gttattccca gcttatcaag
    46681 gcgcaccgct gatgaaaaaa gattttgcta aagaacatcc tgaaatcgtt aaagcactga
    46741 ataaattaag cggaaaaata acagaggatc aaatgattga tatgaattac caagtcaatg
    46801 tcgaaaagaa aaagccgaca gaagtagcac gaatcttcct gaaaaatgaa ggattagtaa
    46861 aggaggaaga tcagtgacta aattaatcga gttcaaacat gtgcaaaaaa agtatgatgg
    46921 aaagtatgtc atcgatgacc taaatctggc aatcaaaaaa ggagaaatct ttgttttggt
    46981 tggtccttcc ggtagtggaa aaacaactac tttgaaaatg atcaatggat tatctaaacc
    47041 atcagcagga gacatctact tcaaaggaaa atcgttaaat gaatataatc tgcagaaaat
    47101 gcggtggaat atgggatatg tgctgcagca aatcgctttg ttcccgacca tgacagtcaa
    47161 gcaaaatatt gaagtcatcc ctgaaatgtt aggttgggaa aagcagaaaa gagcagaccg
    47221 tgtagatgaa cttcttcaaa aagttggctt atctcctgat atttatcgag atcgtatgcc
    47281 tagagagttg tctggaggag aacagcaacg gatcgggatc atccgagcta ttgctgcaag
    47341 cccagatgtg attttgatgg acgagccatt tagcgcatta gatccgattt caagaaactc
    47401 attacaagaa ttggttttgt ccttacacga agaattgggc acgaccatcg ttttcgttac
    47461 gcacaatatg gaagaagcaa tcaagctagg tgatcgtatt gcatttatga aggatggaga
    47521 aattatccaa tgtgacacac cagagcagtt attgatgaat cctaaaaacg actacgttcg
    47581 gcatttcttt gatgaaccga aacagacgaa agagtggcga gtagaagatt tagtcgtcaa
    47641 tggatatttc ttaaatgaaa taccagaaaa tgctcgtcaa caagtttgct ttgatacgcc
    47701 tatgaaagaa gtatattcgc ttctttcggt gtatccaagc attgtgatag tagaaaagca
    47761 aagaagtatt gggtcgctga caagtaaaga aatctttgct tttttaagtc gagaggagga
    47821 aggaaatgaa aacatatgat gcaatcatca tcggttcagg tgtgagcggc ttaagtgctg
    47881 cttatggatt gaaagaagca ggtaaaacag tactagtggt cgaagaagat ctatggggcg
    47941 ggacttgtcc taaccgtgga tgtgatccta aaaaagtctt gttaagtgca gtagaggcac
    48001 gtaatcgggt aaaacaattg agtggaaaag gttttaacga gatcccaact gccaactggg
    48061 aagaacttca aaaattcaaa cgaacattta cggatccagt cccagaaagc cgaaaaaaac
    48121 aattagcaga agctgaaatc gatcatcttt caggaaccgc tcgttttttg gatgattcat
    48181 ctattgaagt caacgaagaa gtcttccatg cggattactt agttttggca accgggcaaa
    48241 gacctacgat cttaccagtg gagggaaagg aatacttgaa aactagtgca gactttttat
    48301 cattgcctgt actgcctaaa gaaatcattt ttatcggtgg tggttatatt gcttttgagc
    48361 tagctacgat tgccaatgct gcagggagca aagtaaccat tgtccatcat aatcaacggc
    48421 cattaaaaga atttgaggcg tctttggtag aggaagccgt ccatcaaatg gaagcatctg
    48481 gcattcagtt tgcttttggt gttgaaaccc aaaagatcat ttcagaaggt actcgctatc
    48541 gtttagtcgg aaaagagacg gaattagtag cagatatgat tttttgtgcg actgggagac
    48601 agccgaatac agaatcttta gcacttgagc aagcgaatat cgtctttgat aaacacggaa
    48661 ttgcagtcaa tgattatctg caaacgagca atccaaaaat ttttgcgtgt ggagatattg
    48721 tttcaaggaa aaccccaaaa ttgacaccag tcgccacttt tgaaggaaat tatgtagcta
    48781 agcggataac ggatgcaaca agcgaaccta tcaaatatcc gattatacct acgatcgtct
    48841 acgccagtcc taaacttgct gaagtaggag ttacaaaaag tcacgcctct tcgtcagatc
    48901 aagtggtaga gatggatctt accagttggt tcacctatca tcgtgtcaat gaaccagttg
    48961 ctaaggctga attgaccttt gaccagcaaa attatttgat tggtgctgca gtgattagcg
    49021 agcaagcaga cgaattgatc gatgatttga cactcgtcat caatcaaaaa ttgactaaaa
    49081 aagagttgga tagctatatc atggggtatc cgacattggc aagtgatctc tcctatttat
    49141 tgaaataatc agcatgataa ctaaagcgct tgttgctttt tccttcttgt gctacacttt
    49201 aaaaaatgaa tacctgtttc tggggatgtc gtagacgaca tgagagtaag ttgtgaactt
    49261 agacccattg aacctgtcag ttaatactgg tgaagggaga aacatagcag acgcttgaag
    49321 cgggttacta tgtcgtgccc atttcaagcg ttttttgtta ttcatattag aagaaaggag
    49381 gtaacaaaat gaagaaaaat ctttatccag cagtcagtat ggcattcatt ttaattattt
    49441 ggcagattgt tgtcatagtt tggaaaatac ctgcctttat tttacccgga cctgctgctg
    49501 tattttctgc attagcggca gatgcacaag tattactttc ccattctgtc acgacattaa
    49561 atgaagcagt gcttggtttg gtaatagcta gcgttctttc ttttattact gccttggcaa
    49621 tggattattg gaagttttta gaaatgtctt tttatccgtt actagtgatt tcacaaatgt
    49681 tgccaatcat ggtgttaggg ccattactta ccctatggtt tggtttcggt atgcttccaa
    49741 aagtgatcct tgttgtcttg ataagctatt ttccgatcgt agtttctttt tcggatacat
    49801 tgaggaaagt atcaaaagag caaatcatct ttttgaaaac gatgggggca gatacaggga
    49861 agatttatcg aatatataaa ataccagcgg gtttatccgg cttcttttcc ggtttaaaag
    49921 tggctgctac ttattgtgtc agcggagcag tcgttggaga atggctaagc gctcaagcag
    49981 gcttagggta ttacatgata cgcgtaaaaa acagctacca gatcgataaa gtttttgctg
    50041 cgatcatttg tgtcattcta ttgagtttat tgctgaatgg cgcttgttca ttattgaaaa
    50101 aagggtatta tcgtatgctt tatatttttt aagagaaggg gatcaaatga aaaaattatg
    50161 gcttttatta ccgctactgt tgcttttatc cgcttgtggc actgcaaaag aaacaagtag
    50221 caaacaagaa ataaaggatt tgaaaaaagt gacacttgtt ttggattatg taccgaatac
    50281 taatcatact ggcatctacc tagcaaaaga aaaaggctat tataaagagg ctggtttaaa
    50341 tgtccaaatc atcgaaccag gagataattc gacaagtatt ggtctagtag gtgcggacaa
    50401 agcacaattt ggtgtaagtt atcaagaaga tgtcacttat gctcacgcag atggacagaa
    50461 tataccagtc aaagcaattg ctacagtgat caaacataat acttctggat tcgccaccct
    50521 atcagacagt aacatccatt caccaaaaga ttttgaagga aaaacatatg caggttggca
    50581 aagtccaagt gaagaagctg tcttaaaagc tgtgatggaa aaagacggcg gggacttttc
    50641 aaaactgaca atggtaggaa gcaatggaga agggccagaa agcttaggaa aatcctcaga
    50701 tatccaatgg tactttgaag gttgggatat gatcaaagca aaagaagcgg gtattgaact
    50761 aaactatatc ccattgaaag aattagatga acggttagat tactatactc cggtaattat
    50821 tacgaatgat caactgatca aaagtgatcc agaattggta cagtctttta tggatgccac
    50881 gaaaaaaggc tatcaggaag ctattaagga tccaaatgac agtgctaaac tgttgcaaaa
    50941 atatgcaaaa gaaaatgatc ggacgttttt agaagaatca caagcattct tgtcaaaaaa
    51001 ttatacggat gatcctgaga attggggatt gatggaagaa aaagtttggc gcaattatac
    51061 agcttttatg caggaaaacg gattgatcaa gcaagatgta ccttcgcaag aactattcac
    51121 taatcagttt ataaaatagg agtgatagat atgtcaatcc aaatcagcca cttgaatgta
    51181 gtcattgaaa acctgaaaat attagaagac atccatttca ctatccctaa agataccttt
    51241 acatcgattg tcgcgccaag cggagccggt aagtcaacat tgctgaaaac tttaacagga
    51301 gtccagccta tgacttctgg aacgatcaaa gtagacgatc aaaaagtaac tggtctccat
    51361 acagcattta gttatatgcc gcaagaagat atgttacttc cttggctgag cgtctatcaa
    51421 aacgttacgt tatatcaaaa aatcaatcat ctaacaatca atgaagaaca agtaagggat
    51481 tatctggata tctttgggtt aaacggctat gaacattttt tgccggaaca attatctggc
    51541 gggatgaagc agcgaacggc cttgttacga acaatcatga atccttcttc ttacttgctt
    51601 cttgatgaac catttggagc gttagatgct atgaccagag ggcagatgca agactggatg
    51661 ttgaagctgc ctaaaaaagc aaagcggact actttacttg tgacgcatga tatcgaagaa
    51721 gcaatttatt tatcagacag gattcttgtg ctttccgccc gtccggcaca tgtgattgct
    51781 gagattcaag tgcctgaaaa acgacggtca cgtgaatggc tactgcagca atcagagttg
    51841 aagcaaacga tttatcagtt attggcaggt gaattagatg ttaagtgatg ctcattgtca
    51901 tttagatggg agtcagagtt tagcactcct tcagcaggaa cacacgattt tgacgatcat
    51961 caattgtgat tcgccagaag aatggaagga aaacagacag cttgcagcaa gtaagactca
    52021 agccttaagt tacggtatcc atccttggaa agcagatagc tatacgtttg aacaagttga
    52081 gccttttttg aaaaaagcaa ggatcatcgg tgaaataggg ttagataata tttggacgaa
    52141 tgtaccgatg actacacaaa aaaaagtatt tgagcgacag cttgcttttg cagccataaa
    52201 tgagaaacct gttgtactgc acacaaaagg atgcgaaaaa gagatcttaa attatatcca
    52261 agcttaccct aatcactatt tgatccattg gtattcttct ttggactatc aacaagacta
    52321 tattgattta ggctgttatt tcagcattgg tcttgatttg aaaaagaatc cagcagtctg
    52381 gcaactagct aaagcagtcc caatcgacca cttacttatt gaaacggatg gactacatgc
    52441 agcagagtgg gctttagggg ggattttttc agaaaaagat tatgtctcac tgcttgaaga
    52501 acagttaaag acaatcgctg agatcaaaga gctatcagtt gaagaagtta aaaaaaatac
    52561 ttatcaaaac ttggaacgtt tcattagatt aggtaaataa aaaagagatg tgacacaact
    52621 agtgtcgcac ctctttttgg ctttctttgt ataaaagtaa actgtttgat taataaatga
    52681 atcttagtac caaccgtttg cttcccagaa tgctttcgcc gcttcccaag aaccataacg
    52741 tgaagtaaca tattgttctg ctactctttc ttggtttgca gcagagtagt caccatttaa
    52801 gtaagaagaa tctaattggt aacgtccgat gtaacgtccg ttcgttgctg tgtaagaacc
    52861 gcttgattct ttttgtgcga tccattcttt tgcagagctt gtgcttgctg gagtagcagc
    52921 agtttctgtt acagcaggag caggttgtgt ttcagcaaca ggcgctgctt gtttttccgt
    52981 ttgaaccgtt tcttgtacaa caggttgttc agcttggact ggtgcttctt gaacggctgc
    53041 ttgaggttca gcagctgctt gtgcagagcc ttctgttggg attgttaatt gttgtcctga
    53101 gta
//
LOCUS       DADGKS010000014        51594 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.014, whole genome shotgun sequence.
ACCESSION   DADGKS010000014 DADGKS010000000
VERSION     DADGKS010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51594
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.014"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(22..1722)
                     /locus_tag="JXV47_000890"
     CDS             complement(22..1722)
                     /locus_tag="JXV47_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486949.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            2229..3389
                     /locus_tag="JXV47_000891"
     CDS             2229..3389
                     /locus_tag="JXV47_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAX1486950.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            3405..3848
                     /locus_tag="JXV47_000892"
     CDS             3405..3848
                     /locus_tag="JXV47_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1486951.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(4331..4861)
                     /locus_tag="JXV47_000893"
     CDS             complement(4331..4861)
                     /locus_tag="JXV47_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HAX1486952.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            4966..5517
                     /locus_tag="JXV47_000894"
     CDS             4966..5517
                     /locus_tag="JXV47_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAX1486953.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(5670..6143)
                     /locus_tag="JXV47_000895"
     CDS             complement(5670..6143)
                     /locus_tag="JXV47_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAX1486954.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            6281..7753
                     /locus_tag="JXV47_000896"
     CDS             6281..7753
                     /locus_tag="JXV47_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAX1486955.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            7750..8460
                     /locus_tag="JXV47_000897"
     CDS             7750..8460
                     /locus_tag="JXV47_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HAX1486956.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            8812..9096
                     /locus_tag="JXV47_000898"
     CDS             8812..9096
                     /locus_tag="JXV47_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HAX1486957.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(9413..9796)
                     /locus_tag="JXV47_000899"
     CDS             complement(9413..9796)
                     /locus_tag="JXV47_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HAX1486958.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIK"
     gene            complement(9798..10382)
                     /locus_tag="JXV47_000900"
     CDS             complement(9798..10382)
                     /locus_tag="JXV47_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HAX1486959.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(10429..11904)
                     /locus_tag="JXV47_000901"
     CDS             complement(10429..11904)
                     /locus_tag="JXV47_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HAX1486960.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            12085..12396
                     /locus_tag="JXV47_000902"
     CDS             12085..12396
                     /locus_tag="JXV47_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486961.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(12511..14847)
                     /locus_tag="JXV47_000903"
     CDS             complement(12511..14847)
                     /locus_tag="JXV47_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAX1486962.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            14989..15657
                     /locus_tag="JXV47_000904"
     CDS             14989..15657
                     /locus_tag="JXV47_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1486963.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            15660..16703
                     /locus_tag="JXV47_000905"
     CDS             15660..16703
                     /locus_tag="JXV47_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAX1486964.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(16940..17821)
                     /locus_tag="JXV47_000906"
     CDS             complement(16940..17821)
                     /locus_tag="JXV47_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAX1486965.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            17980..18708
                     /locus_tag="JXV47_000907"
     CDS             17980..18708
                     /locus_tag="JXV47_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HAX1486966.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            18864..19181
                     /locus_tag="JXV47_000908"
     CDS             18864..19181
                     /locus_tag="JXV47_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAX1486967.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            19174..19782
                     /locus_tag="JXV47_000909"
     CDS             19174..19782
                     /locus_tag="JXV47_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HAX1486968.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            19798..20628
                     /locus_tag="JXV47_000910"
     CDS             19798..20628
                     /locus_tag="JXV47_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HAX1486969.1"
                     /translation="MRLKHFLITGIGLMLTGGLLAGATYTLGAQKSLTWDNGPRLIDM
                     VTETKKIKDANKIVIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKK
                     STGAIISLEDTSAQITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSF
                     NEFTGGTITAKDELGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSL
                     HEMENSGYTIQTSGESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD
                     "
     gene            20766..21254
                     /locus_tag="JXV47_000911"
     CDS             20766..21254
                     /locus_tag="JXV47_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HAX1486970.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            21305..22177
                     /locus_tag="JXV47_000912"
     CDS             21305..22177
                     /locus_tag="JXV47_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HAX1486971.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            22353..22715
                     /locus_tag="JXV47_000913"
     CDS             22353..22715
                     /locus_tag="JXV47_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAX1486972.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            22724..23476
                     /locus_tag="JXV47_000914"
     CDS             22724..23476
                     /locus_tag="JXV47_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1486973.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            23490..25292
                     /locus_tag="JXV47_000915"
     CDS             23490..25292
                     /locus_tag="JXV47_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1486974.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            25569..26609
                     /locus_tag="JXV47_000916"
     CDS             25569..26609
                     /locus_tag="JXV47_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAX1486975.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(26661..28805)
                     /locus_tag="JXV47_000917"
     CDS             complement(26661..28805)
                     /locus_tag="JXV47_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAX1486976.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(29162..30535)
                     /locus_tag="JXV47_000918"
     CDS             complement(29162..30535)
                     /locus_tag="JXV47_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1486977.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(30535..30930)
                     /gene="rbsD"
                     /locus_tag="JXV47_000919"
     CDS             complement(30535..30930)
                     /gene="rbsD"
                     /locus_tag="JXV47_000919"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002829567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HAX1486978.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(30958..31875)
                     /gene="rbsK"
                     /locus_tag="JXV47_000920"
     CDS             complement(30958..31875)
                     /gene="rbsK"
                     /locus_tag="JXV47_000920"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HAX1486979.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(31983..32996)
                     /locus_tag="JXV47_000921"
     CDS             complement(31983..32996)
                     /locus_tag="JXV47_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAX1486980.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(33077..33676)
                     /locus_tag="JXV47_000922"
     CDS             complement(33077..33676)
                     /locus_tag="JXV47_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAX1486981.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            33862..34563
                     /locus_tag="JXV47_000923"
     CDS             33862..34563
                     /locus_tag="JXV47_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1486982.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            34573..37284
                     /locus_tag="JXV47_000924"
     CDS             34573..37284
                     /locus_tag="JXV47_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAX1486983.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            37735..39363
                     /gene="treC"
                     /locus_tag="JXV47_000925"
     CDS             37735..39363
                     /gene="treC"
                     /locus_tag="JXV47_000925"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HAX1486984.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(39423..40604)
                     /locus_tag="JXV47_000926"
     CDS             complement(39423..40604)
                     /locus_tag="JXV47_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAX1486985.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            40856..42379
                     /locus_tag="JXV47_000927"
     CDS             40856..42379
                     /locus_tag="JXV47_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAX1486986.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(42448..43176)
                     /locus_tag="JXV47_000928"
     CDS             complement(42448..43176)
                     /locus_tag="JXV47_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1486987.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(43189..44469)
                     /locus_tag="JXV47_000929"
     CDS             complement(43189..44469)
                     /locus_tag="JXV47_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAX1486988.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(44610..45212)
                     /locus_tag="JXV47_000930"
     CDS             complement(44610..45212)
                     /locus_tag="JXV47_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory regulator AgrB"
                     /protein_id="HAX1486989.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            45457..45663
                     /locus_tag="JXV47_000931"
     CDS             45457..45663
                     /locus_tag="JXV47_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1486990.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            45975..46694
                     /locus_tag="JXV47_000932"
     CDS             45975..46694
                     /locus_tag="JXV47_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAX1486991.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(46775..47458)
                     /locus_tag="JXV47_000933"
     CDS             complement(46775..47458)
                     /locus_tag="JXV47_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HAX1486992.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            47677..49863
                     /locus_tag="JXV47_000934"
     CDS             47677..49863
                     /locus_tag="JXV47_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAX1486993.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            50209..50619
                     /locus_tag="JXV47_000935"
     CDS             50209..50619
                     /locus_tag="JXV47_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAX1486994.1"
                     /translation="MIKVYTSPSCTSCRKARAWLKANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            50633..50989
                     /locus_tag="JXV47_000936"
     CDS             50633..50989
                     /locus_tag="JXV47_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HAX1486995.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT        16852 a         9073 c        10262 g        15407 t
ORIGIN      
        1 ggatgtattt atcccttttg cctaagcacg taaaagcttg tatctatgat aaataaataa
       61 acatagcaag gtaaaccagc caatcaaagt aagagaaaga atgaaataga aatagattgg
      121 cgtttgataa tgaagcgtga gctcgttgat tcctttttgc tgcttcacga ttggggtccc
      181 gatatctgtt acttcataat cagtcaatgt ttttccattt tgctgtagca cagtccgatc
      241 gtagacgata acagggatat gaacagtttt gtccccagtg tttttccact tgattgtcaa
      301 aagaccgcct ggatgtgttt ttataaaagt tgtttcgttt tctagtattt cttcgttata
      361 ccggtcgtat ttattgtctt ttgtctcctt atagattggc agatagtcag gtgtggtttt
      421 ttggaaaacg aacaagctgg tagacatatc tttgctgaag aatgttttcc ttgcttcttc
      481 cggcgtatcg aatagataag tatgtcgact gacaaatgtt tcattttccc acttttccag
      541 atgctggtat aagttctgga tcgtctgtgc tgaaaaaata agaatgccaa atatacttaa
      601 aagacggaac cacttttgtt cagaccactg gttcagtgaa agggcaaggt aaagtagaag
      661 caatagcgta aatggcacga aaaatcgaaa tggaaactgg atcaaactaa taaaaggcac
      721 atttttttcg atcaatgtcg tccatggaat caagctagta gaaagaaaaa agaaaacaag
      781 acttgtgtac aacacgattt tttggaataa ggtgttcttt tgttgaaaga aaataaaaag
      841 caaaaaacct gataatatca atataggaaa ggccttaggg taatggagcc aataactgcc
      901 atccagatct atcgcctttt gactcatttc tctgttaaca aagggaggaa gaatcttatt
      961 cccactgtaa acaatagcta atcctgccca aatatttgct gtcagaacaa aataaagcaa
     1021 gaccgactta atcagttgaa gcagtgcttt tcctttttca gtctggttaa aaaagtaata
     1081 aagataaaaa gggatataca tcaaagctaa catgatcgaa gacagtaaat ggatctgtgt
     1141 cataagtccc actgagacag cgactttgat aacagggaac tttttatgaa ggacgaaatc
     1201 agcaataggg atcatacata aaggataaaa acaagtcccc cagctagtga atccttggtt
     1261 gatagaccag tattgaatag aatacgtact catgaataaa acggctactg gtacacttac
     1321 ccaatttcga acattgacat atctcagtaa aatcagcata gaaaatcctg aaataagata
     1381 aagaatgaaa tttgaaagaa tctgataatg aaaccagcta cctgcaagca acacgatcaa
     1441 tccttgtaaa taagcgaaaa atgggccgta aacggcattc acgatcctgc cactttgctg
     1501 gaatccataa agggaaggaa aataatggaa atccccatat ttaatttgtt gcgcggcatc
     1561 atagaaccga ttgtaatgga atggggcatc agcacccaaa attagtttat gtgtgaataa
     1621 atgaggcatg agaaatgcca aagcaatgaa aaaaattgct aaaaatgggc catatttttt
     1681 caattgtcga actcctttgc aaactttaga taaattcatc atatatccta tgcgagaggt
     1741 aggcaagaaa ttagaaaatt catgaaaata tttatgaatt ttacaagaaa aacataagtg
     1801 aaagttctaa ggagagagga tgcgacataa gttttgttgc atctccttgt tttgaaacag
     1861 aatttttctt aatactcgaa acaaagtagc tttttcatga cctctcggta aacggtgttc
     1921 aatcagctgc ttctcggtaa taagctcact agcctagaaa atatgagaag ctattttctg
     1981 actagcgctc ttattactca aagcataacg cagttttcac aacctcttcc ttaaacggtg
     2041 ttcaaaagct tgcatctgcg gtaataagcc caacccaaca aaaaatatga gtagctattt
     2101 ttttgggctg tacttattac ttgatgcagg acagcttttt cacaacctca tcggctttca
     2161 ttttctattt ttttcctgaa cccatataat aaaagaaaga acaaaaaaac ttgcaaggga
     2221 ggacacatgt gaagcagagt aagcaaaaac agtctcgtcg acttttgttt cgtttgtttt
     2281 tattaatatg tatcgtcgta gggttactga tcgctttata tccattttat gtggattctt
     2341 taaatagttt tattgatcaa aaacgtatcg aacaagtaca aaaacggacc gcagctgaaa
     2401 ttgaagtgca gcgaaagaaa atggaggaga aaaaccaacg attaactgac caaggattca
     2461 atcctggtac tgatcctttc aatgaaaaga acagaaatga aagtacaaca tccagccaat
     2521 tagaggaatg gctgatcgga agtatcaata tacctaagat ccaattaaat atttcacttt
     2581 atgatcggct caatggtagg atccttgaaa atggagcagg cgtcttgcaa ggaacctctt
     2641 tcccgcttgg tggaaattcg acgcattcag tgatctctgc tcacagcggt ttacctaatc
     2701 gacggttatt taccgaatta gatcgtttag aaaacggaga cacgtttatt ttgactgttt
     2761 tgggggagaa attggcttat caagttaaaa atatacaagt ggtactgcca gatgacacgt
     2821 ctgttctaac gatttcagaa ggagaagact tagttacctt gcttacatgt acgccgtata
     2881 tgatcaacac gcatcgtttg ctagtgacag gacatcggat tccttataac gaatcggtaa
     2941 aaaaagaaga aggaaaagga aatcaggaaa gaaccatgcg gcaatggttt attcttgcag
     3001 gaacgataat agctgtagtc atactgttag tgtttatcgg acgactaatc tatcagtata
     3061 gattaagtaa aaaagtgctt gatttttcat ttattattag tgattcgtca gggaaaccgg
     3121 taaatggtag ttcattcatt ttgaaacata agaaaaaaac acttactaga aatggtgtgc
     3181 cgttttcagt acaaagcgac catcatggga aagtcaagct ggatcaattg cctggtggaa
     3241 cttatcgaat cgtttcagct gatgatccta aagttgctgt ttcttttggt attagaaaag
     3301 taaaacaaga gaagatatac ttttttgagg ggcgaaaact tgtaaaagag cttcaaaaaa
     3361 atggttttta ttttaaaatc aatgaataag taaggagaga aaaaatgatc cgcacaacaa
     3421 caaaattgtc tgccaaagaa ctggaatctg ttctatcgat ttggctgcat gctaacttgg
     3481 attctcatga attcattcca tcaacttatt gggagaatca agtagaatct gttaggaaag
     3541 ctttaccaga tgcagtgatt tacttagcag aaatagatca agaaattatt ggttttgctg
     3601 gggtgattga tcagtttatc gcaggaatct ttgtgaaaag ggaataccgg caacaaagaa
     3661 tcggtacgca actaatgaaa aaaataaaag aaaccaataa aacactgact ttgacagtct
     3721 atcaaaaaaa tcaatcagct attcatttct atctttcaca aggttttaca attcaaacac
     3781 agcaaaaaga tgaagcagta aatgaggagg aacttgtgat gaaatggaat caaaacgctg
     3841 atttttgatg aacagaataa cgaaataatg ctcccagcct aattttttgc tgggagcatt
     3901 atttcatttt gaagtcacta atttaactgt gtgaatatgc agttgttaca atctttgata
     3961 aacggtgttc aatcagctga ccctcggtat tagctcaaaa aacggcaaaa tatgaggaac
     4021 tatttttcca tttgtttctc taatactcag gtcaaaacgc tgatttcaca acctcttgat
     4081 aaacggtgtt caaacggctg cttctcggta ataagcccac tagcctagaa aatatgaaaa
     4141 gctattttct aactagcgtt cttattactc aaagcataac gctgatttca caacctcttg
     4201 ataaacggtg ttcaatcagc tgaccctcgg tattagctca aaaaacggca aaacatgagg
     4261 aactattttt ccgtttcttt ctctaatact caggtcagaa cgctgatttc acaacctctc
     4321 tttcacaacc ttattttact cgtttataat tttcatcgaa gtattttccg ctacggatat
     4381 catctggcat tccatcgtat ggttcttcgc taataacatc ttcattgtct atacctgcat
     4441 cacccatata agtgatcgta gcaaattcag gaacaagtaa ttttggataa gtttcatatt
     4501 tttcacgagc tgcttccatt tctgcgatat gttcgttttg gaaagtaaca gtgatttctg
     4561 gatgttcttc aacccattta gggaaaaaga tcattccgtg aagtttcttt tcatttggca
     4621 taaagtccaa tgccacgtct gtccctgttg gctctgtcca agtgattttg aatacgccgt
     4681 ccgtcaattt aacgatatca gcttcttggt cttttaccca acggcctttg accattccgc
     4741 catggatacg gtaatcaaca gtatggtcat ttttggcata ccattcatat tcccaaccat
     4801 tgtcatacgt atagataaag tgagttccaa taaaatcttc caattcttta aattctttca
     4861 tgtttaagca tctccttata aattaaaaca tgtaataaac tacatgtttt cgattactca
     4921 tttatgatag aatggattta aagatttgtc aaggagggaa aactgatggc aagaaaaaat
     4981 acacttcgat atattttgtt agggttatta agtaagaaga agatgacagg atatgaattg
     5041 aatcaatcgt tcaaaaatga aataggagaa ttttggcaag caaaacatag tcagatttat
     5101 cctgaacttg caaaaatgga agagcaagga atcattcagc atcaagtaga gatcacaggt
     5161 gaaaaattgg aaaagaaagt ttatgaatta acagaagaag ggaaggaaca attggcagag
     5221 tggattcata cacccaccaa tgaactaccg gttaatcgag acgaatttgt tctgaaattg
     5281 tatttcgtca aagacgtgaa tgatccggca ttagtagaaa ttattcagca gcagcgtgac
     5341 cttcatgaag aaaaacgact tcatctatta gagcgaaaaa aaacgatctt tcctactgaa
     5401 aaagaaaaac atgaaaatta cggacactac ctgattttag cgcatgcgat caatcgggaa
     5461 acagaatatg caaattggct aacagatgta ttagaagaaa gtaaccgaaa aaaataaaaa
     5521 aatatccgaa cagtgatgga gaattccttt ctatatgaaa gaaacgcaga tcaccgttcg
     5581 gatattctta tgttcaaaca ggcctttttt caagtattta tgtagcatct acttattaaa
     5641 aagcttggta cttaggagat tagtggcgtt tagagttctt ttaacaactg ttcgtagtca
     5701 gctttttcat cgacaggaag gagcttgtaa gttaattcgt ctgtctcgtt gtcatgaatg
     5761 atgtacatct tagcattctc ttctttgaag ttaccgattt gtaaaatcgt atagcgttcg
     5821 tcgatcaatt cgatatcttt gattgctttt gaaaaaactt tacggacatg gtgcattttc
     5881 ttttggcgga tttctgcctt ttctgcagct tttgacaaag taaatccgtc atctaaatat
     5941 tttttgatca gttctacttt tatgactgta ggtaaacgat attttctagg acaattcgca
     6001 tcagcttcga tcgaacgaat gaatcccttt tgttcccaat accttaattg acgtggagac
     6061 acacctacga tatcacttaa ttcactgatg ccaacaacca attgatcatt ttccaacaaa
     6121 cgtttaaggg aagccccaac catttttgtc actccttttg tcctcttgct tcccttaatt
     6181 atatccgtat taacttatgt gtcaagtagg ttgacaaata gcgaatttag gactaaagta
     6241 ttctagtagt ttcagaaaaa attcagaaag aaggagaaat atgagtaaca accaacccgt
     6301 agatatttac ggaaaaccat ataatcggac acttttagtt gttgtcttat taattggtac
     6361 attttgtacc gttttgaatc agaccttatt gacgacagct tttcctacat tgatgaaagc
     6421 tttcgatatt tcagcgtctg atgtgcaatg gttaacgact ggtttcttgc tagtcaacgg
     6481 gatcatgatc ccaataacag catggctgat caataaattc agttcaagaa atttatatct
     6541 ttctgccatg acgatctttt tgatcggaac gattacttgc tttacagcac ctaattttag
     6601 tacattacta atcggtcgtt tgatccaagc ttgcggtgtg ggagtatcga tgccattatt
     6661 gcaaaatatc atgctatcta ttttcccgcc agaaaaaaga ggatcagcaa tggggatgtc
     6721 agggatcgtt attggacttg ctcctgcttt aggccctaca ttatctggtt atatcattga
     6781 taactaccat tggcgtgact tgtttggtat ggtactgcca atcgttgttc ttgtcttggt
     6841 tttagcattc ttcctaatga aaagtgttat tccattgtca aatcctagca ttgatatttt
     6901 atccgctatt ttatcaacga ttggattcgg tagtttactt tacggatttt ctagtgtagg
     6961 agatgacggc tggggaagct tgaaagtaat tggtttctta gttgttggtg tgattttcat
     7021 cgccttgttc tcatggcgtc aattacattt ggaacatcca ttcttggaac ttcgtgtatt
     7081 caaatcatct acattcacga ttgcagctgt tttagctggt gtaacaaata tggcgatggt
     7141 aggggcagaa atggtcgtac cattgtatat tcaaaatatt cgtggagaat cagcattcca
     7201 ttctggcttg atgttgttgc cgggtgcatt gatcatgggg gctatgatgc ctgtgacggg
     7261 tgcgattttc gataaatacg gcgcgaaacg tttagccatc acagggatgt tcattttgac
     7321 agcggcaact gcaccatttg ctttcttgac aaaaacgact ccagttttat atatcgtgat
     7381 cctttatgcg atccgtatgt ttgggatctc catggtcatg atgccggtaa cgacttctgg
     7441 tatgaatgca ttgccaaata acttgatcag tcatgggaca gcggtaaata atacattccg
     7501 tcaaatcgca agctcgattg gtacagctat tttgatcagt gtgttgacga atgtgacaaa
     7561 agcaaatatc ccaagcaaat ctgtattgga taatacgcca ttagcttata aagatcaggc
     7621 aatcaatgcc acactgtcag gttaccatgc cgcgtttatc gtagcgatca tctttgggat
     7681 tcttggcttt attattgcct ttttattgaa gaaaaaagaa cctgttctaa tgaaagcggg
     7741 ggataatgca tgattattgg agttttgatt gtcagcttgc ttgcttttgc tttaacgaac
     7801 gtgttcgcta aaaaaacatg gcaaaccttt ttatctttga ttttcggact aatcttcgtc
     7861 gcttcactaa gtttgatcgt cgctaatttg tccaatcact ttggaatgga aaaagtaacg
     7921 gaaacaaaaa cagaaaaaat tgtttccagt gctgattccc aaggagcaga tatgcttttg
     7981 tataaagctt tagggaatgg aaaagaaaaa gtgtatcttt accgaacaaa tgaaaaacaa
     8041 gaaaaaccaa aagcaactgg tacggataac gaaacaaata aagtagaaaa gacagacggc
     8101 gatgctgaaa aagtgacgaa aactacttat tgggaataca aaaacgacat gtataaattc
     8161 tggttcaata ttgctgataa caatcacgaa tatgacagcc gagtgaatac attcaaaatc
     8221 ccagagacat gggtagaatt aagtacggac caagcagcca agttagctga attagtgaag
     8281 aaacagcaaa gtacgatgga aagtgaagca aaagcttatg ttcaagacgg tatggtaaaa
     8341 gcaatgactg aaaatccaaa aatgagcaaa gcagagcaag aacaacgtac gaaagcctta
     8401 gctgctgaat tccaacaaca agcattcgca aaattagtga aagaagcaaa aggcgaataa
     8461 tattttgaac accatgtagg aggttgtgaa aaagctgctc tgcatcaagc agtaagaaca
     8521 atcagataaa aatagcactc catatttttc atctgattgg gcttagtgcc gtagatgcaa
     8581 gcttttgaac accgtttaag gaagaggttg tgagcctgcc gtttaactct gagtcacaag
     8641 gagcaatttc aaaaaacagc ttctcatgtt tgttgactat tgtgacttgt gaccgaggag
     8701 ttggcaggag aacaccgttt attcgaaaaa aggaactgcg acaagacttt tgtcacagtt
     8761 ccttcttttt tttgctatgc tatactagat gtaaaaaata ggagaaataa aatgagggaa
     8821 atttattctt ttgaatcaaa aatctatgct tccgaagtcg gcaagggcgg ggcatatatt
     8881 atttttccgt atgatataag aaaagaattc ggtgctggaa gagttaaagt ccaagcaact
     8941 tttgacaatg tgccgtatga aggcagtatc gtgaatatgg gcgtgaaaaa tccagatggt
     9001 tcagtctgct acatccttgg actacgaaaa gatattcgta aaaacatcgg aaaagaaatc
     9061 ggtgatattg tagcagttac agtgaagcaa aaataaaaga ggttgtgaca aaagacgtgt
     9121 cacaacctct tgataaacgg tgttcaaaag ccagtttctc ggtagtaagt caaatttatg
     9181 caaaaatgtg gaaacccatg tttacaaaat ttttcttact actcgaaacg aagcggcttt
     9241 atcacaacct cttgataaac ggcgttcaat cagctgtccc tcggtattag ctcaaaaacg
     9301 gcaaaatatg agaagctatt tttccatttt tttctctcat actcaggtca taacgctgat
     9361 ttcacaacct cttctttcat aatggttttt caccatcttt ataataaact ggttatttga
     9421 tatggaaatc tattttttcc aaccaatcta aaatcttgta acctaactct tctgacatcg
     9481 gaaaagaggc gttgatttgt gcattggaga tatggtcaac atggataccg gaagtgatcg
     9541 tacaacttcc cggaacggca gttttgatga tcacagctat tttttcggct aagacatcgt
     9601 ctttatggaa ccgaccatcg tggctaggga aacgtacagt ttgcatctct gtatcacgag
     9661 aaaatgtagt gactgttccg atatgtggtg tatctccgcc tgttaaagtg atcaataagt
     9721 ctttaccgat tactttaaca gcagcttgga tcgtgaaacc tagtttggtt acttcaacta
     9781 tcgtttcttt ttccatatta atcaccctgc caacgttttg aatgctcatt tacaatttca
     9841 aattgatcca aaagtttcat tgtatggtga ttaacaagat cttggatcgt ttgaggctga
     9901 ttataaaaag caggaattgg tggtatgatt tgcacaccta gtcgtgctaa tttagtcaag
     9961 ttttccaagt gaatggcatt taatggcgtt tcacgaggaa caatgactaa ctttcgttgc
    10021 tccttcattg ttacatcagc agcacgtgca atcaggttgt cgcctaaacc aacagagata
    10081 cctgcgactg ttttcatact tgccggtacg atgatcattc catcggtcaa aaatgatccg
    10141 ctggcgacag cagcacctaa atctttgttt gaataatggt aatcaaacag gctttcgaat
    10201 tcagttagtg ataagtcgga ttccagcttt aagttctgtt ttgcccatgg actgatgatt
    10261 ccgtgtgttt ctatcatcgg atattctttt agtttcttca ctaggttgat ggcataaatg
    10321 gtgcctgaag cgccacttac accaatcacg atttttttct tccgttgtgc caattgttcc
    10381 attttccgca ctccttttta tgatgtcaaa acagttgcag atcattcatt atttcaaata
    10441 tttttcccaa tcttctactt cttggaattt tgcacgtaca aaatgttctt tcatatcgaa
    10501 aggaactgta ccgtcaaaga tagtttttgc acttatccca cggaaacgaa tagagccagg
    10561 attatattct ggtaattctg atgggtccaa tggatggttc ctcattcctg ggatcacgat
    10621 gatatcttta tctccttgga aacgagtgtt gaaagtccaa actacatcgt tcatgtcgaa
    10681 aatatcaaca tcttcatcga ctaaaatgac tgtcttcaat tctttgaagg ctgataaagc
    10741 aagaatagct gcttgacgct gaataccttc atccgcttcg ttttctttac ggatttgcat
    10801 gatggtcatc aatttaccac cacctgcagg aggattgtag acatttacta cttttcctgg
    10861 aatagcttta tcgaccaagg caagaatact tgcttctgta ggaataccgg ccatagatac
    10921 gtgttcttca ctgggaccaa tcgttgtttg catgattgga ttgtcttttc ggtgagtaac
    10981 tgctttgact ttcactactt gtacagctgg attagcatcc ccagtatagc caggaaattc
    11041 tggcattgct tttcctgagt tcgtgttgat atcttcttgc attgtttcat ttggcatgat
    11101 ttctgcttca atgatgaatt cagcacgagc aatacccact tcatcgactg ctataccatc
    11161 aacgatttga ataggttcgt tacgcaaagc tcctgcacac catagttcat tgtagccaag
    11221 tggagtggta ggtggttcga aagtcgtgcc aatggcaatt gctggatcta aaccaatatt
    11281 gatagtgata ggcattggtt tattcaaggc ttcgaattgt ttttggaagt gaccaatgtg
    11341 gcgtccgcca ggcatgatgt acataccgat cgtatcttta tcttctagaa ccatacgatg
    11401 gatcgttaca tcgctcattg ttttttctgg atctgatcct aagactacac ccattgtgat
    11461 gtatggacca gcatcttcag gagtatttgt aggtgcaggc aaaatgttgc gaatatcgaa
    11521 gtctgcatcg gtagctagat gaacgacttc ttgtgctgga gcgtctgctt tgtctacttt
    11581 cacaggtttg attggatttt ctacagcgtc tttcaagaaa cgaccaagtg ttcgataatc
    11641 atggtgcaaa atttcaccta cacgtttacg actagccatt gttccgatgt tcacacgtgt
    11701 gccggggaaa cctttgatat tgttgaaagt catagctggt ccttcttgag tcggacgttt
    11761 tactgtaccg ccagcaccga tataacggta aacaccagat aattctgctt caggatcgat
    11821 ttcaatatct gtttcgtgat attgacctgg aagtgttttt agttcttcga tgacttttct
    11881 taaatcatac ggttgatctg tcatgagaga ttcctcctta gttgtcttta cctatctata
    11941 gtaaaaggtg aaaaagagga aaacaattca acttgttcgg taaagtattc tacaatggaa
    12001 tggatgcgtt tttttgataa tagaataaac tatgatatac ttatcactaa aagaaagcgc
    12061 atacttagtg ttggaggaag gaaagtgaaa aaaatggagg agtcatttcc taaagcagta
    12121 aaagtggaaa atatagcgaa tattttgaaa gttacatttg aaaacggaga agtaaaatac
    12181 gtgaaatctc attggacaga agagataacc gatgccttgc aatttggaaa aaaaggaaga
    12241 ggaaaaagaa aaaatcttct cgcactttct cgtaatatgt ggattgggac tgaagtaacg
    12301 attgaagcag atggaacagt attcataaat ggaaaagaca ggtatacgcc agaagagttg
    12361 tggtacaaag gaaagaaaag tataccagaa ttataaaaaa taattaaaaa aaacagcgcg
    12421 aaacaaggaa catattactt cctcgtttct tgctgttttc tactatttca gcgctcttat
    12481 gactcaaatc taaatgtggt tgtcacaacc ttattctgca cgcaaagcga tagcggcgtc
    12541 ttttttcgct gccattcgtg caggaagatg accgccaagc atcgtcaata tagtagagac
    12601 gatcactaga ataatcgcat ggacaggatt tagttgagca acatttttta gatccgtcat
    12661 gttgtataag atgctattga tagggaacgt agctagccat gcaataaaca cacctaatat
    12721 cccagaagaa atacctaaaa tacacgtttc tgcgtcaaat acgcgagtga tgtctttttt
    12781 acgtgcacct aaagctttta gtacaccgat ttcttttgtc cgttcaatca cagatgtata
    12841 agtaatgata ctgatcatga tcatacttgt tactaaagag atccctgcaa aagcaataag
    12901 gacataagtg atagcatcca tcaatccgcc agtcagttca gtcatcgttc cagctaaatc
    12961 agtataaatg attttatctt catctgattt gcctttattg taatcatcta gataatccaa
    13021 gatcttttct ttgtcttcaa aattgttcgg ataaatcatg atacttgaag gcaagctgtc
    13081 tccacctaaa taactaagca atgtttgttt ggcattttcg tcaacttttt cagtagttaa
    13141 gacatttaca ccactgtctc tttgagcttt gacgatttct gattctttgt tttcgttgac
    13201 gatttgagtc gttaattgat cgctataagc gattcctgga gataagagat tcattgtaga
    13261 agaagatttc acgcgtagga tccccgagat cttcaattca tcagaagcat tctgatacat
    13321 cgcatcataa tctgtattag ggataaaatt cccagttgga agttttgtat agtaagtatt
    13381 gttgtttact aatttgaatg ttgtaccaac gatatcatca aaatcaagtt tttcgtcttc
    13441 tttcacatca aatccaagat tcttcaatgc gttgatatta gtattattat tgccgtctac
    13501 gatcagcacg acatctgttg ctgaggctgg ataacttccg gcaagtaaag aataattgtc
    13561 ttttaaaaag ttttctttgc tagtgtcaag ctgtgtaggg aaacttgaca ctcccacacc
    13621 tgtcattgct gacatcgtac tagataaaga aagagattcc gtatcaggat tttgattcga
    13681 gaagctgaca ggctgtactt tgccatttac atcacgtaaa agattgattc ctgtagtacg
    13741 ggtaaatccg atattattac ttaagttagg atcgatgtct gttacgtaat cgacgtatgt
    13801 ttgatcaatc ttattcgtgt gctgtgcttt atcttcttcg ctgacttttg cagtaatcgt
    13861 tttgctgtct ggataatccg ctttgcttgc acccaatccg gcatcgtcac gagtctggtt
    13921 agtcgttacc ttagaaatag taatcggaaa tttcgccatc gtttcagctt gcgtgttatc
    13981 gatttgtttt tggaatccag aagaaaggga cagaacgatc gcgattccga tgatcccaat
    14041 actggaagca aaggaggtca agaaagtacg tccttttttt gttcggatat tgttgaagga
    14101 aagctttaac gctgtccaaa aactcatctt tgttctgcgt aagttaaatt gatcatcttt
    14161 tggtcgttcg atgtgaggat gggaatctgt taagatctta ccatcagaaa attcaatgat
    14221 tcgatctgcg tattgatggg ccagttcagg attatgtgtg accatgatca ctaatttttc
    14281 tttcgataac tcttggatca attccatgat ctggatactt gtttctgtat ctaacgctcc
    14341 ggttggttca tcgcacaaaa ggatatctgg gtcattggct agtgctcgag cgatggccac
    14401 tcgctgcatt tgtccaccag ataactgatt tggcttttta tgcatatgat ttgtcaagcc
    14461 gactcggtgc aatgcatctt ctgcccgttt tcgtttttcg tctttagaaa caccacttaa
    14521 tgtcatccca agttcaacgt tttcaataat gcctagatga ccaatcaagt tgtaactttg
    14581 aaaaatgaaa ccgatagagt tgtttcggta ggcatcccag tcactgtcct taaagtcttt
    14641 agtagacttt ccgttgatta ccatatcacc ggaatcataa ttatctagtc caccaatcac
    14701 attcagcata gtcgttttac cagaaccact aggacctaaa atcgctacga attctttttg
    14761 tctgaaagcg acagacacac catccaatgc tttggtggtg gtttcgccga ctttataata
    14821 tttttttata tcttttaatt gaagcataat cacccttctc ccgtattgaa atattcggta
    14881 tactaataag tatatcagaa caatgatcgt agtatacgaa ataaatgtta actgaagatg
    14941 aactacaaga aaaaatctag aaatttttca aaaaacagag ggagatcaat gaatcgtatt
    15001 ttagtagtag aagatgatcc gcaattacag ttgctttacc gttctgtgtt ggaacgagcg
    15061 ggcttttcag tcatcaccgc attgaatgga gaggatgcgc tgaaaaaact agaagcgaca
    15121 cgtatagaat taatcattac agatatcatg atgccgaaaa tggatggcta tgacttgcta
    15181 gactcattac gtagcaccag atttgacaca cctgttctaa tgattacggc aaaggccgat
    15241 tttgaggata agaaacgcgg gttcaaatta ggagcagatg attatatgac aaaacccatc
    15301 gatgtcaatg agatgatcct acgtgtggaa gcattgcttc gacgttcaaa gatcaattac
    15361 agcagtagct tgataatcgg acaaacaaaa ttagagctag atgcttatac agtgttacaa
    15421 gatcagcatt cgttgattct gcctcaaaaa gaatttctgc ttctgtataa attactgtct
    15481 tatcccaaca agatcttcac tcgccaacag ttgatggatg atatttgggg attagatacg
    15541 aatacagaag aacgaacgat cgatgtacat atcaaacgtt taaggacccg ttttgaaaag
    15601 acggaagatt ttcaaatcat cacagtacgg ggactaggct ataaggcggt tatttaaaga
    15661 tgaaaaaaaa gctattttca caattatgga tctattttgc tagtattgtc ttcatttcga
    15721 tcttagtgac actgctgtgt tttctcggtt ttattttctt attgtctcga cattctatct
    15781 cgcctgctga atcggctgga aaaccaacgt tatacccgtt attcgtcttt gcggggttca
    15841 gtatggtcgt gggtacagga atatcgattt ttgttgggcg gcgtatcctg catccaatca
    15901 gtgcgctagg gacaaatatg agtctggtag caacgggaga tttttcgatt cgaatggatg
    15961 aacagcagaa agtagcagaa gtacagcaac tgtataaaga tttcaacgtt atggtccaag
    16021 aactcaatag tatcgagaca ctgaggaatg actttgtgtc cagtgtatcc catgaattca
    16081 aaacaccact agcaacaatc caaggatatg ttcaattgtt acaagcccca aatctctctg
    16141 acgaagaacg ccaaatattt ttatatcgga ttatcgaaag tatcacgcag ctttcacaat
    16201 taacagagaa catcttaaaa ttgaacaaac tggaaaacca gcgtatccaa ctggaaaaga
    16261 aagagtatcg attagatgaa caaatcagag aagtaatcgt tttttttcag cctaaatggg
    16321 agaaagaaca gctagaattg gatatcgaac ttgctgcagt aaattacaca ggcaatgaag
    16381 agtttttgta ccaagtgtgg ctgaatatca tggataacgc cataaagtac aatcaaatca
    16441 atggacagat tcatatcaaa ctatttgaga cagccacaga gattgtactg gaagtgaccg
    16501 attcaggtgt aggaatgaat gaagagacca gagatcgaat gtttgaaaaa ttttatcaag
    16561 gagatacaag tcgtcaaatt tctgggaatg ggctaggact ttcactggtt aaaaaaattc
    16621 tagaactgca tgatggacgt attgattata gcagtatcga aggagtagga acgacagcaa
    16681 tgatacggtt aagtaaacaa taggaaaaag aataaaaccc ctaaaaattc tattgaaggt
    16741 ttttaggggt ttttagtcgt ttttttgtga ttagggaaat gttcttacgg ttcttttggc
    16801 ataaaaatcg ctgctttctt attgaactac gagaaatgtt agaggtgtca ttgaaacaag
    16861 gacatgatgc aagaaagaga gcgaaagtca tgcgtcgctc tctttttttg ggtggataga
    16921 tggacagaaa atgtagggct tagttttctt cttgatttaa atactcccaa aatgtatctg
    16981 aagccaaaga atgctcaccg actttacgag taaatgcaag ataactctct gttgttggag
    17041 aaatagggag aatcacagta ttttctttta atagattctt gactgttttt tccataacaa
    17101 tagcaatccc catgtcattt gcaatcatat tgatgatcaa gtcgattctt gctcctttat
    17161 aagagatttt tggttcaaat ccagcttcgc gacacagatc tagtacaggt tgatacaagt
    17221 tcgtagtggg gccaaggagc aaaaagttct cctttttcag ttcgcttaga tccaatttct
    17281 ttttactagc taaaggatga tttttaggta gaactgctac aaaatcgtct gtttcagtag
    17341 gcaaccactc aatcgaactt ggtggggcct ggaaacttct agcaaagtgg atcgtgtcac
    17401 tatgttcatt ggcgtcattg taagttaatt cgacactttc cacttctttc aactggactg
    17461 taaattcagg atggcgtttc aaaaactcgg tgattttgga aaaaccttta taattgatca
    17521 ttgtcggtat cgttaagata tttaatgaaa gattgttgtc tttcgtatag gtttcaagca
    17581 cttcttgcat agcatggtat tgttctacga cattttttac atatgggagc aataagcttc
    17641 cagcttcggt caattcgatt tttctatggg cgcgttcgaa taatttgacg tctaattctg
    17701 tttctaacga aagaatctgt ttagaaatat ttccttgggt ggtgaattgt cgatcagcag
    17761 ttttggtgaa attcattgtt tcggctaaat caagaaaaac ttcgaattta tggatatcca
    17821 tcatattcct cctacttatt ccaataaaga atactttaac acaaaaaatg aattggtgta
    17881 atcttctctg tctgttacaa tctttcttgc agcgaaagca ataattacag aaatttttct
    17941 gatttttttc gcttcgtaga aaaagagagg agttttttga tgccaactgg agttttgatc
    18001 aatgtaggtt ccgttttgtt tggcggacta attggcggat tagtaggaaa taaattaagt
    18061 gaacatttta aagcacagct gacgatggtt tttggtgtgt gttcgatggg gatgggaatc
    18121 tattccattg cgccgatgaa aaatatgccg gctgttattt ttgctttagt gataggaaca
    18181 gcgattggtt tgattgttca tttaggtaat gggataaata agggggctgc gctgatgcaa
    18241 gtacctattt ctaaaatctt ccctagtgaa aagcttggta tgacccacga tgaatttatc
    18301 agcacattag tgacggtcat tgttctattt tgtgcaagtg gtacggggat ctatggaagt
    18361 ttagattctg ggatgacagg agacagtacg attttgattt ctaaatctgt ccttgatttt
    18421 ttcacagcag ctatttttgc gtgtaattta gggtatgtcg tttctgtgat agcaattccc
    18481 caattcatta ttttttatat tttgttctta ttggcaaaat ttatttatcc attgactaca
    18541 ccagacatga tcttagattt taaagcttgc ggcggattct tgatggtcgc taccggtttt
    18601 agaatgatca acgtgaaaat gttcccagta gctgacatga tacctgcaat gatcgttatc
    18661 atgccactga gctggatgtg gacaaattgg attatgccac tgttataata aaaatcaaag
    18721 agaagccatt ttttgctgac taaaaaggat caaatctttt agtcagtttt tttgtatttg
    18781 acaaactgat tttgaaacta tattatatgt tgtataatat agattgaaat aaaatattac
    18841 acttgagaat agaaggtgac gtaatgcaca tccagattcc aactgttctt cttgatggta
    18901 ctgtgctagc agcattaagc aaggaagata tgtatgggta tgccttaaca aaaatcgtac
    18961 aagaaagtct ctctgtcagt gaatctacac tatatccggt tttgagaaga ttgaaaaaag
    19021 aaggatatct tgagacctat gatgaacctt ttgaaggcag aaaccgtcga tattactcgt
    19081 tgacaccaat gggaagtcgt catttagaag aaattattga tgaatggatt gtttttcgag
    19141 attctttaga ccggttattg gaggagagca caaatgaatg aatatttgaa tgaagttgtg
    19201 gatcatcttc aagaaattcc tgaagacgat cgttttgatt tgatccagta ttatgaggaa
    19261 tattttttag attctggaaa aacattagat cagatcattg atgaatatgg tacaccaaag
    19321 cagtttgcct taaaattaaa aatcagttac ttttcagaag aagaacaagc agaaaacgag
    19381 ttagtgaaaa atccaaaaag acaaattcgc ctgatttggt taatcattat cggtttattt
    19441 gcttctcctg tcctcattcc actagcactg gggtttatat tggttattgg gggactattg
    19501 gttgctttac tagcgctcat ttttagtatc tatgttttat gtatcagtat cttaggtgtt
    19561 ggcctattca tgatcatctc aggaatcagt gtgtttggac aatcgattct gagtggatta
    19621 ttctttatcg gtgtcggtct gttcgccaca ggaagcgcag tatttatttc gccactgttg
    19681 ctgaaaggaa caaaagggct tttttatgtc atgatgaact ttgttaaatg gatgggacga
    19741 cgttttatta caaaaagaga tctgcattca gcgggcgttt gaaggaggac acataaattg
    19801 agattgaaac attttttgat taccggtatt ggtctgatgc ttactggtgg cctcctagca
    19861 ggtgcaactt atacattagg cgctcaaaag agtctgactt gggataatgg tcctcggttg
    19921 atcgatatgg ttactgagac aaaaaaaatc aaggatgcaa acaaaatcgt catccatgca
    19981 gaaaatcaaa cagtttcggt catacgcgga ttggattttg agataaaaac gacttatgat
    20041 aagacagaaa agccagaaat aaaggagaaa aatggcgtgt tgactgtgaa tgcagtcaaa
    20101 aaatcaacag gtgcaatcat tagtttagaa gacacaagtg cacaaatcac tattgttgtc
    20161 cctgcagatc atgaattatc tgaattgaca atcgaaggga ataatagtgc aattgatatc
    20221 aacgaagtat caatcaaaaa agtgaatact aagacacatg atggctgggt atcgttcaat
    20281 gaatttacag gaggaacaat aactgcgaaa gatgaattag gctcacttcg attagatgag
    20341 gccaatgtgg ataacttgat cgtcacaggt gaaaacagca acttccatct agaagacagt
    20401 ttgatcagca aagaaggaaa agtcatccta aacggtggca atttatcttt gcatgagatg
    20461 gaaaacagtg gctatactat ccaaacgtct ggtgaatctt atattgaaaa agactaccag
    20521 ccaataacaa atactttgtt agaacaagga cagaaaaagc taaagatcac tgctaaagac
    20581 acatcgatca atattacgac ggatcaagag gacaatgaaa cagattgatc ctgtactcaa
    20641 ctggatattt taagaaaaaa cagcaaagat ccttccaatc tttgctgttt ttcatcgctt
    20701 aacgcacata actatagtaa aataagaaag aaaatatcta aaaagaaaac agggtgaaag
    20761 agtatatgaa ggtagaagaa ggtcaaagag aaaagttaaa aacagaaatg gaaagattac
    20821 atacttatat cactcaacta agccaaacct tctatgatcc agacaaagaa aaagtgatgg
    20881 ttaattaccc gaacaattca gaaggtcgcc aattagagca agtgtaccat gaagttttca
    20941 aacatttatt gacggtgaag aaagagctgg attattattc tttaccgatt atcgatacag
    21001 gaatattgaa gtatgatggg aagaaggaac gatttatctt taaatctgtt cgggaagatt
    21061 tgcctctttc agcagggatg gatctagagg tcttggtaga agactatttt acagaagaaa
    21121 agcactgggt tcgaacaaaa ttggattatt taccgcaggc agccggaggg acacaggcaa
    21181 gcggttggta catcactgaa gacaaagagt tagaactaga aggtgtaatg gcgcgtattc
    21241 gaaaaaaaaa ttaaaaaagt aacattagat atttattgaa ggataaagga gcgcaggaag
    21301 tagcatgaga gaaaaaagag cattttatat caatggttat gcagggattg tcggattggt
    21361 cgtattagct ttagttggat tgtttttctt ctatttaggt atgtggcaag cgaaagtttg
    21421 ggcacttttt ttaagtattt ttctttggtt gatcacgtta ttgttgttaa gttcggcaac
    21481 tgtagtcagt cctaatcaag caaaagtaat tttgtttttt ggacaatatt taggtacgat
    21541 tcgagaaaat ggctttttcc ttacgatacc tttggcacaa aaaatgactg tttcgttgaa
    21601 agttcggaat ttcaatagtt ctgttttaaa agtcaatgat ttggatggaa accccatcga
    21661 aatctcagca gtagtagtct ttaaagtcgt tgatacagca aaggcattat tcgatgtagc
    21721 gtattatcaa gattttgtag aaatccaaag tgagacagcc attcggcata tcgctagcca
    21781 atacccgtat gatacattca atgagaatga tttgacgctt cgaggaaaca cgacggcagt
    21841 gtctgacgag ttgcaaaaag agctgcaaga gcgtttagca gtagcaggtg tcgaagtaat
    21901 cgaaacacgc ttgaaccatt tagcctatgc aacagaaatc gctagtgcca tgctccaacg
    21961 tcaacaagca aaagccattt tgtctgctcg acaaaccatt gttgaaggag ctgtcacaat
    22021 cactcaaatg gccttagagc aaatcgaaga tggacaagaa atcaatttca ccgatgatcg
    22081 gaaagtccaa ttgatcaata atttacttgt ctcaatcatt acagacaaag gaacgcaacc
    22141 tgttatcaat acaggcgaca tgaaagaccg taagtgacat actttttgta agataggaag
    22201 aaggagttta ggacggatta ttgtcttgaa ctcttttttt agttgtttta aagaaaatga
    22261 caaaattgaa agaagaatga tagttgattc gaaggcagaa ttgttcgctt ttttctataa
    22321 tcagtatata aagtaagaga gaaggggaaa aagtgaaaaa acttctgatc ggtctacttg
    22381 ttttcatcgt tgtggtactt gcaggggtga aaatcgcaga ttacgtagtt atgggtggag
    22441 aagaatacta tgtacaaatt acgacagatg gtacaaaaac agtttcaaaa tcagactctg
    22501 gacaagaaac agtcaactat agatatatcc tgcctggcta tacgaaagag ggtaaggaaa
    22561 aagaactgga cttcaaggga caattgactc gaccgcttcg taaaggagca tatttaaaaa
    22621 tcacctggaa caaaaataaa ggtgtcactt cgtatgaaga agtcgaaaaa aaagacgtgc
    22681 cgaaaacagc actggaaaaa ctaattaaag ggtagggaaa gaaatgaaca aaatagtcga
    22741 agtacagaat gtaacaaaag tatacggaaa aaacaatgag aaaaagacgc aagcattaag
    22801 cggcatcagc ttcgatgtag aaaaaggcga atttattggg atcatgggcg cttctggttc
    22861 tggtaagtcg acacttttga atattttatc cacattagat aaaccaacag atgggcatat
    22921 ccgaatcaat caaaaagatg tgaccacatt aaaaggaaat caactagcag attttcgtgc
    22981 gaatgagatt ggctttattt tccaagattt caatttatta gaaagcttga cagcacaaga
    23041 aaatatcgct gttcctcttt ctttacaagg cgtcagacca aaagaaatca agcaacgtgt
    23101 ccaaaaaatt gcagaacgtt tatccatctc tcatattttg gaaagctatc cttctgagat
    23161 ttccggtgga caaaaacaac gggtcgccgc cgcacgtgca ttgatcacac aaccaacgat
    23221 tctattaggg gatgagccta caggtgcgct ggattccaaa agtgcccggg atcttttaga
    23281 tacgatggac gaattgaata caaaagatca tgtatcgatt cttcttgtga cgcatgatcc
    23341 gttttctgca agttattgcc aacgtatttt attcatcaag gatggcggta tccatcaaga
    23401 agtgaaacgt ggagatcaaa gccgtgattc cttctatcga gaaatactat ctattcttgg
    23461 aaacttggaa cagtaggggg agattgacta tgctttggaa attatcactt actgggatca
    23521 agagccgttt aagagactac ttggtgttat tctcaggatt agttatggca tctgctattt
    23581 tttacatgtt tgaatcaatg gcaagcaacg aagctttttt gaaaagtaat acgatcgttg
    23641 cggctacagt tatcattttc cgattcggtt ctgttttact agggatcatc acattcgttt
    23701 atattttata tgcaaattcc tttttgatga cgatgcggca aaaagactat gcaatgttta
    23761 tgatgctggg agcaaaaggc agaaaaatcg cacagatgat tttttctgaa acattcttag
    23821 tagggatcgc agctacttta gtgggttcag ctgtcggtgt aggattgaca agtatcgtcc
    23881 accgattatt agtggatcag ttagatctca atatttcgca ttttacacct tttagtattc
    23941 acgggttgtt gatcactgtt ttgttttttg ctgttttgtt tttattagct gctgttgtca
    24001 atgctttttc gattgtcaaa aaaccgattt tagcattgat tcgtgcggat cagacaccaa
    24061 caagaatcaa gcagcataaa ttcttgtttt tccttgaagt agtactggga attgcttttc
    24121 taggctgcgg ttactatatg atgaaacacg tggggaccta tcaagtcttt ggtatagggg
    24181 tagccttagt tacgatcgta ttaggaactt atttcatttt ccattctgtg atcattttct
    24241 ttttatcatt actaaagaaa tcagaacaga tttcattgaa aaaattgaac aatttcacat
    24301 tgtcacagtt aaactttcgt attcgtgaat atacacaaat gctctcaatg gtcgctatgc
    24361 tgtttgcctt ggcactgggc gctttgacgg taggattagg ttttaaaaat gaaattgcag
    24421 acttgacaga aaacaattct ggatatgatc tagtgatgaa taatcctcgg gcagaagatc
    24481 agcaaaaaat caaagaactt tcaccaacac tttctgcttc ttatactcaa aaagaagatg
    24541 cgggaacgat ttactataat gcaagtgaat ttgcggctca accattgatc atgataaaac
    24601 atgaagatgg aacaccgccg aagatcacga aagaaaaagt tcctgctaaa aaaatgaatg
    24661 aactgactgt acaagaggaa cttcgaagct atgaattgcc ggaacagcaa gaaaaagaaa
    24721 tcaaggtagt cagtcaatca gaatttgatc aactgaactt gccacaatcc actttacagc
    24781 tagttcaggt aaaagacttc caagcaaacc tgaaaccaat cgaaacactt gttgctcaaa
    24841 ataaaatgaa caatccatct ttgcaaaaag tagagtacag caaccagaaa tatgaaatgt
    24901 atgaagtgta taatggtcta ttctctggtt ttgaatttat gggattcttc ctaggtttag
    24961 ctttcttgac catgcttgct agctgtttga tgttcaagat cttgtcagga agcaagagtg
    25021 acattgctcg ttatgaaatg cttgaaaaga taggaacacg acgcgggttg cttaaacaat
    25081 cgatccgtag agaagtaggc gtgttattct tagcaccagg aatcttaggt gtagtccatg
    25141 tcttattcgg attacaaatg tttggtctat tcatgcaaaa tccatacaaa gatatttggg
    25201 ttccgtttac gatattcttc gtattgtatt tcatctacta tgtactgacg acatggttat
    25261 atactggaat cgtattgaaa aagagattgt gaaaaagctg tcctgcatca agtaataaga
    25321 acagccaagc aaaaatagct cctcatattt ttcgtttggt tgggcttatt accgcagatg
    25381 caagcttttg aacaccgttt gttcggaaaa agaggttgtg acaatatttt tgtcacaacc
    25441 tttttttcac ggtcttttat tagaatatag taaatttttt ctcgttactc acggaataag
    25501 ctgttaagaa aacggtttcc atgtatactg gaatcagtgc aaatgaaaga aaagagggtg
    25561 caaggaacat ggaaatcaat gaacaaaatt ttggcgaaaa ctatcacttg attacgatca
    25621 cgaatcaaaa tgggacatct ttgtctgtca gtgatcttgg ggcacgggtt gttcattttc
    25681 aaacaataat cgataatgaa aaacgagagt tgatcttagg ttttgatgaa gcaaaagaat
    25741 atctagaaaa agacccttat atcggtgctt caatcggacg tatggctgga cggattacga
    25801 atggcacatt caaattagat gatgaaacgt tcgaagtaaa aacagacccg gacactggtc
    25861 attgtttaca tggtggtgca cctagctttg aagccaagca gtggcattat acagtcatca
    25921 atggtgaaaa cgaagcatcg gtcattttct atcagactag cccagatatg gaaaacggat
    25981 ttcctggaac tttagatgta gaagtacggt atacgctgac gaacgatgat acatggcgag
    26041 tgacggtcca agggatcagt gaccgcaaaa cagtattcaa tcctacaaat catgtctatt
    26101 tcaatttaac cggtgatcca gcacagtcaa tcgacgaaca tatactttgg ttgaatagcc
    26161 gattatttgc tacgctcaat aaagatacaa cgcctacagg agaagtagtt tcagtaagtg
    26221 gcacagcatt tgacttccaa cgtcctaaaa aattaggtga ggtctttgcc agtgattttc
    26281 gccaatcaat gatagtgggc ggcatcgatc atccattttt gttgaaaaaa caatctggtt
    26341 tactaaatgc tgcggaattg acaagcccag atgaaaaagt atcgatccaa gtaaaaacag
    26401 atgcttcagg aatcgtgatt tttacagcaa attttggaga agatggaccg gaaatgcgcg
    26461 ggaataaatt agtaaatcat ggcggtatca catttgagac tcaagaactg ccaggagcgg
    26521 agcgacttga aagttttgga gatgtcactc tggaacctaa ccaagtacgc gagtttgtaa
    26581 cggaatacaa aataaatata aagaaataga ataaattaaa aagggagtgt gacagtgtca
    26641 catccccttt ttaatttatt ctatttcttt aaaggcagat caagccagaa tgatttgtct
    26701 aaacttaaca aggttagtac aggaacagtt gcagctttaa ctgtacgagt agttgtttct
    26761 ggtatctgtc ttgccgtaaa attgttccac aaatcccaga ttgaagcgac acggaagatg
    26821 gaagaagcgt tgttgacgcg ttttatcgtt gaaaattcta atcctgtgat tggcacgcca
    26881 tctgttgtcc atttgattgg cacatcgaat cgcttagaca tattgaggat ttcagcgttt
    26941 gcttcttcag ttgttgctgc ttcttttttc ggttcatcat attttgtcag gtcgtacgct
    27001 tcgatgatcg cgttcaattt ttgtgaatat tggcgatctg tagcataacg tccttccaaa
    27061 tatttggttg cttctttgta gtcttttgtt tccgacttcc aagttggttt gtagaaatca
    27121 ggattgccag tcagtccatt tttgatcaag tcggcatagt cttccaaact ttccttgtaa
    27181 gaaggatatt tacggaattg tgcgcggatt tggtagcttt gtccggaact atcttgttca
    27241 agtgtattga aggtcacgct gcttccttta tatgatcctt tgataccaaa aaggttatga
    27301 tttggttcgc ttgataataa gctgtttcca gatccacttt caaggatagc ttgagccatc
    27361 atgactgatg cgtagattcc ttctttttgc ccgatttcct gtgcatcatc tgcaatcttt
    27421 ttcaagaact gatcagttgt ttggttttga ctgaaatgga acgagccatc taatccatct
    27481 aaaatagatg agccgcctgt cagcgaacct gaagcagcag gtaaacctgc taagtttact
    27541 cggacagcaa aatcaggcgt gaaatctgaa atagaagtta ctcgaacttt atctcctggt
    27601 tgaggcgcat ggataaattg tccgttccca atatagatac ctacatggtg agtaacaccg
    27661 gaagaaggtc cccagaagac gaggtcgcca ggttgggcct gacttactgg aatctgcgta
    27721 cctgcatatt gctgttcgcc tgtccagcca ccgatataat gaccggttgc tttcatatat
    27781 acgtaataag tcaaaccaga acagtcaaaa gtatttggac cttttgctcc ccatacatat
    27841 ggttttccaa gatgcttgaa tgcttctcga acgattgctt gttggacatt cgttgtattt
    27901 gtaggcaata cagcatcaat tggtgatttt acaacaaaat cagaagaagc agaagatgga
    27961 ttctctatac cgctttgatt tgctgtattt ggacgagatg aagcattgtt cgttccgcca
    28021 ttcgatgaac cattgtttgg atggtttggt tctctctgag tatttccatt gttattcgat
    28081 ccagatgggt ttgtttgatt cgaagaattc ccgctgttcg aattattgtt attattgttt
    28141 gaattatttg aaccattatt attgttgtta ttacccacat ctggtttgtt tggcgtttcc
    28201 ggatctggtg tactagggac ttcttcacta ggatcagttg gtttctctgt tgaagtatcc
    28261 ggtccagctt taaattctgc agtaatagat aaattgttcg tacctactgt aaaggtcttt
    28321 gcatcataat ttacttcttt ggcaccatta acagcgactg aagcaatttg ttcaccttca
    28381 gctggcgtaa tagtgtaagt taccttcgtt tccgctaata aaccttctac cgttccactt
    28441 tccgtaatat ccaaaggttg ctgttcaggg gaatccgctg tcgaagcagt cagttggatc
    28501 ttaccaatca aagaaggagc aattgtaagg gaatatgtct cggctggctt ttcattttct
    28561 gatggatcag ccggatcaat ttcagttggc tcggtcgatc ctgttgttga gttagttgtt
    28621 ccagttgggt cttctgtaaa agaatccgtt gtttcactag tagctgagct ggatgtagtc
    28681 gtatctgttg tgactgtttg atcagctatt tgattatcta cggcaaatac ggtattggtc
    28741 gacaaaacag acggagcaat cagccaagta gcagctagca aacgtatcgt ttttttattt
    28801 ttcataataa actagtcctt ttcctttcat tgattttctg tcttattcag cattcattag
    28861 acattttttg gaacagataa tcgtgtcgaa aagctttttc ttttcataaa tctgtctgtg
    28921 tattctaaat aaaacaattt gtaaataagc aacgagcatt cattcgtttt tctttgacgt
    28981 tcattttatt gcatagacca cctttgtttg gggataaaca agtggggata aaaatggtta
    29041 tgcatatgta aattatacca aagtttggaa agtatcacaa aaatttataa aaataatgat
    29101 cctaaaaaga aaaagactga aatatgtgat aaacatctca tacttcagtc tttttcatta
    29161 actattcata agacattagg tcttcatcaa acccgctaac gagagtagtg atcattgcta
    29221 cgactagact aacagccagt cctgctaagt accagaaaaa agtaccggaa atgaatgcag
    29281 gcaatgtggt cagactacca aatacaaaag cgatcgcttt cacttgggca aatcccatta
    29341 cagctccacc agcagctgca ccaatgcaag cagcaacaaa tggttttttc aatgggatcg
    29401 caattccgta aacagttggt tcggtcactc ccgcaagtaa aatcgaagca aaagcagaac
    29461 cggagatcga acgggttttt gaacgtttac ttcgcagaaa tacacctaaa gctgcaccag
    29521 ccattccaaa attggctgct cctgtcaacg gaacgattcg gtcgaaccca taagcagaga
    29581 tattactgat catgacaggg tttacagccc attggatacc aaatattacc aaaatattcc
    29641 aaccaccagc gatgattgcg ccactgatcg gtccgttaat atccatcatc caagtaattg
    29701 cggcagctaa accttcgcca aggtaaacac ccgcaggccc gaataccatt aacgtcaaag
    29761 gaaccgtgat aactaatgaa agtaaaggta caaatactaa ttgcatattt tcgcgaatat
    29821 attttttgag gaatttttca acaaaagaat aaaagaaaat acctaaaatc gccggcatga
    29881 cagtagacgt atactgcatc agtactacag gaatccccag aaaatcagta gctgctttgc
    29941 cactgtctga aagtaaagag gtcagattcg gttcaatcag tgctgcagca atgacagccg
    30001 caatatatcc attcacttta aacgttttgg cagcagaaaa agcaagaaag attggcagaa
    30061 aataaaagac ggcattcgac gcagcagaca aaatatgata agttccgctt gtttcactaa
    30121 gccagccaat cgtagtcgct aaaacaacca gaccttttaa tataccagaa ccggcaaaca
    30181 gcggaatgat cggcgtaaag atttccgata tcaaaccaaa tagtttttcg atcggattta
    30241 gcttttcttt cggagctgaa tgatcgattt gacgcgtcaa ttccttgtaa gcaggagcca
    30301 atccctgatc catgattatt tctgcatatc tatcgagtaa aatgaaatac ttaatggaag
    30361 ggatttgctg ttttaatttt tctgcattgg ctactggctg ttttttcaat ttgatacgaa
    30421 gccgagtcgc acatggaagg acagaatcaa tattgtcttt tcctcccaac tgttcaatca
    30481 gcatatgaat ctgctcggac agtaccatct gttcaggatt cattgtcgtt tccattagaa
    30541 gaccactcca ctcactaata taatattggc gtaaggtgtc atttcgcctg tacgaataaa
    30601 tgcatgacag ttattcaact cttttttcat ttcttcatgt gggataaagc taatcggtgt
    30661 atctggtaac aataatttga ttttttccaa tatttccggg ttcattgtct ttatttcttc
    30721 cgccaattca atcgattgta cctcaagttc ttctaaaacg ttttctaaaa cagataaaaa
    30781 acttggaaga ccgtttgaga cagccaaatc tattttttca gtaccaaagg ggacaggcat
    30841 gcctgcatcc ccgatactta atttatcaaa gtgccccatt tgtgcgatta ctcgtgaaat
    30901 atctgaattg attacttttc cttttttcat gtttgtttct tcctctcatt gttaatttta
    30961 gactgctgat tgttctaaag cttcgcggta agggatagaa ggttgcgcac cataagactg
    31021 cacagcaaca gaagaggcta gatttccata aaggatcgct tctttcaagt tactaaggtc
    31081 tggctgaagt gtgctgctta atgcgccaat aaatgtatca cctgcggctg ttgtgtcaac
    31141 ggcatccact ttaaaagcag ggacgatacc gtgttctttt tctgtatgat agaaagcgcc
    31201 ggcactgcct agtgtaatga ttactgttcc aatacctaat tcatggagtt tttcggctgc
    31261 tgcgaccaaa ctgttatgat ctgtcactct gattcctgta atgatttctg tttctgtttc
    31321 atttggtata atgatatctg tcttttcaag tagttcagta ggaatcgttt cacgagctgg
    31381 tgcaggattc aggatcgttg tttttcctgc gtcttttgca atagaaaaag ctaggatcgt
    31441 cgcatctaag ctactttcaa actgagcaat aataaagtca ctgtttgtaa tcagttgctt
    31501 gttttttagg acttcttgtt catggaaagc attatttgcc cctgcatgga tcaagatact
    31561 attttctcct gctgcgtcta ccataatcat tgcttgtccg gttgtggcgc cttggatttc
    31621 agctatccca gatgtatcga tgttttcttt tgtcagtaga tctaataact gttgtccttc
    31681 gctgtcagcc ccaacgcctc caataaaaga tgtccgtgcg cctgaacgtt tggctgccac
    31741 tgcttggttg gcacctttac ctccgccagc gtgaaaaatc tcatgcgcat gcatcgtttc
    31801 gcctggcttg ggcatgttgg ttaaacgaag ggtagtgtcc atattaatac ttccaattac
    31861 tgtaaccgtg ttcattttac aaacctccaa ctatctcatt tattttgatg ggaaaattat
    31921 tttttaaaac gttttagtaa aacgttttaa tagttcgata aaaatatagc acaccttgaa
    31981 agctatttca agggtgcagt tgaaaatctt ttttctaatc gtacaggtaa tcttttttct
    32041 tcccattctt tttctgggaa ttggatccga tctaacaata acttggcaga tgtttgtccc
    32101 aattcgaaga ttggttgtgc gatcgttgtc agtttcggct tgatatactc gcacatatct
    32161 atattatcat agccaataat gctgtagtct tcagggatgc tttttccagc ttcctctaat
    32221 ccgcgatata atccaaaagc taattcatca tttaaagcaa acacaccagt tgcagcagaa
    32281 tcaagaagtt ctgctgtgat ctggtagcca ccttgttttg agaactgtgt aggtaagagg
    32341 atcagttggt cgtgagggat ttggtaaaca tcaagagcag atttaaaccc ctcaatccga
    32401 gcgtggacat tttccggtgg attttcagga tagacaaggg cgatcgtttg atgtcctaga
    32461 ctaagcaagt gcatgcccgc taggtaacca ccgcgaaaat cgtctgttcg tacggcatca
    32521 ctaaatcctt cagatttttt ctgatccaaa acaatgaagg gccggccttg ttttttcaaa
    32581 ttttcgttga ttgcatctgt agagacagca gaagtcgcga taatgaatcc atccacacct
    32641 cgacgtgtga gctcggctag atattcgatt tctttttgat gatcagaatc agcattacat
    32701 aatatcgtga cgaaattctg cttatacaag atatcctcaa ttcctcgcat cagtgtactg
    32761 aagaatggat tcgtgatatc aggaacgagt acaccaattg ttttcgtttc cttggtaatc
    32821 atttgtctag caaaatagtc aggctgatag cctaattctt ctttggcagc taaaactttc
    32881 tgaacagttt tcggactgaa tttctccgta tttccattta atatcaagga gacagttgtg
    32941 attgaaacgc cggaaagttt agcgacttct ttgattgtga tctttttttt caccatgttc
    33001 atactcctat ctaaatcctg tggttatttt cccatgaaat caaaaagaag taaatgaaaa
    33061 tcacgtgtgc cagtacttat ttgctttgtt ggatagcttc gattatttgt ttcgttgagc
    33121 gtactcgtgc agttttcgga aatatctttt ttatgaacaa ttgatgggat tctttgtcac
    33181 gatcactgca agcatcttca gcaagcacga tatggtaccc gtgttgaaag gcatctaatg
    33241 cagtagcata tacaccgttt gttgtcgcta caccgcttaa aatgatagtt tcgattccac
    33301 gccggcgaag ttgaagatca agagaagtac caaaaaaagc acttggattg tattttgtga
    33361 tagtcaacat attatctgta tctttcaaag aatccttcaa aagtaaatca gtgaattctg
    33421 gaggtacaga agcagtcatt ccacccatat cagtttgttg actcaaataa gggaaagtgg
    33481 agatgtctac gttcactaaa actttcaagg cagcggtacg tttcaatgtt cttactaaca
    33541 aatcattgtt tgtcagaata gatgctgcag tgtgtggaga gagtgtaccg ttatttacga
    33601 tctctttttg catgtcgatc gcgacaaaag cagtttttga taaatcaaaa atcatatttt
    33661 cctttaaatc attcatgatg ttccttcttt caaataacaa tgttttttat gtaagtaaat
    33721 cataaatcgt ttatttgtca actaaattaa aggattcctt tctttagtct agagaaattc
    33781 agtggtaaaa taaataagtg tgagaaaacg cattcgatgc atagatatag cgagaaatat
    33841 cgtgaaaatg gaggaatcag agtgaagtat gtcgaagtaa aaaatgaata caaacgatac
    33901 aaaatgggag aaacgaccat tacagcaaat gacgatattt ctttttcaat tgaaaaaggc
    33961 gaattagtga ttatacttgg tccaagtgga gcaggaaagt caacgattct taatatttta
    34021 ggtgggatgg atacacctga tgaaggtcag atcattattg atgacacaga tattgcgcaa
    34081 ttttcagata aacagcttac tgcttaccga cgaacagatg tagggttcgt tttccaattc
    34141 tacaatctcg ttcctaatct aacagcaaaa gaaaatgtgg aattggcaac ggaagtttct
    34201 cctgatgcgc ttgatcctgt agaggtattg aggcaagtgg gcctagctca tcgattgaat
    34261 aactttccgt cccaattatc aggaggcgaa cagcagaggg tttcaattgc tcgtgcacta
    34321 gctaaaaatc ccaaacttct tttatgtgat gaaccgacag gcgcgctgga ttttgaaacg
    34381 ggcaagcaag tattgaaatt attgcaaaac gctagcagac aacacggcaa taccgttttg
    34441 atcattacac ataattctgc tttagcgccc atcgctgata gagtcattca cattaatgat
    34501 gctaaagtaa ggtctgttga attaaatgat catccttcat ccattgatga gattgtatgg
    34561 tagggggatt ttatgaaaac aagaacatat cttaaagcag gttttcgcga aattcggcaa
    34621 tctaaaggac gattcattgc aatcatcctt attgtcatgc taggaacact tttatttgta
    34681 ggtgtcaaaa ctgctggacc tgtcatgcaa aaaacgatgg atcactatgt tggtacagca
    34741 ggactttctg atttgcaaat cgtttctact ggtggcttga cacaaaaaga tattgctcaa
    34801 gcagaaaaga tcccagatgc aaaagtagaa acaggaaaac agatctatta ttccaatact
    34861 ggcaaaaacg aagtgattca aatattttct tataacaaaa ataacaagca gaacaagcta
    34921 caattaactg atggaaaact cccggaaaaa ccaaaccagc ttgtattgga tgaaaaagcg
    34981 gaagatgaag ggtataaaat cggtgatatt tatcagattg attcagatga attgaaagaa
    35041 aaagagtata ccatcacggg ctttgtccgt tctccattgt tcatcaacaa tttggagaga
    35101 ggatacgcga acgtcggaaa tggtagcgtc gattattttg tctatttacc tgaatccgtt
    35161 tttaaaacag atatttattc tgtcttatat cttgatttta caaacgtaaa gaatttgaat
    35221 acgtacagca aagcttacaa agataaaatg gagcaaaatc aagaaaaggc agaaaagtat
    35281 ttacaagatc gacccgaaga acgcttagaa gagctgaaaa aatcggccaa cgaagaatta
    35341 gaaccggcac agcaaaaaat agcggatggc aaagcacaaa caacgcaagc aagaacacgg
    35401 ttagaagatg ctaaaaaaca gttagcgcaa cagtcagcaa ctatccagca gcttcctgaa
    35461 gcgcaacgaa caatcgctgt tcaaacatta tctcaacaag aagctcaact tgctgaacaa
    35521 gaaaggcaat tagttgagaa agaacgtgaa ctggcctctg cagaggaaga attgaatcga
    35581 aatgcagaaa aaattgaaaa tttaactaaa ccatcatacc tatacaatga acgttcagaa
    35641 aatgtcggtt ttcaagaatt tggtgatctg tctgatcgta tcgctgcgat tgccaatgtt
    35701 tttcctgttt tctttttctt tattgccgca ttgatcacct ttacgacaat gacacgtatg
    35761 gtagaagaaa accgcaggga aatcgggaca ttaaaggcgt taggttatac gaaagttgaa
    35821 atcgcaaaaa aatatgcaat ctatgcaagt ctagcctcag ggataggtat tgttttagga
    35881 acgatattag gaacgaatct tttgccaagg atcatttttg agctgtctaa cgagcggtat
    35941 gatattggga gtgcgcttat tttttatgac tggccgccga ttttacaagc agctgccgca
    36001 ttcttcattg ccgcatttgg cgctgcaatg atcgttttat tcaaagattt aagagaacgg
    36061 cctgctgcat tgcttcaacc gaaagcaccg aagccaggga aacgcatttt tcttgaatac
    36121 atcactccgc tgtggtcacg ccttagcttt aatcaaaaaa tcagttaccg aaatctcttc
    36181 cgatataagt caagaatgct tatggcgatt atcggaattg ctggatgtgc cgggctgatg
    36241 gttgcaggcg tgggattgaa agattctcta agttctgttt cagccaaaca atttggaccg
    36301 atcattgact atcaagcaat cgttacattg gattcatcca cggaagatag tcgtcaaaaa
    36361 gcagcggata tgctgcagaa gcaagaaaaa gtaaatgaga tcctagctat tcatactcaa
    36421 accgtagaat tgagaaaaaa aggacatgct tcgcaaagtc tgacagtgat cgtaccaagt
    36481 aaaacagctg atttggatcg ttttatccat ttaactgatc ttgaagagaa cccacgctcc
    36541 ttgcctaaaa caggaatcgc tattacgcaa aaagtagcag aactatttga cttatctaca
    36601 ggagatcata tttcgcttta tgatgaagat caaaaagaat ggaaagtcga agtaaaagaa
    36661 atcgtgaaaa actatctagg tagctttatt tatatgtccc ctgaatatta tgcttcagtt
    36721 actgatcaat cgatgatgga taatgcattt ttgctgcgta cagataagat gacaacaaaa
    36781 gaagaagaaa tgctttccga gaaactgctt gccacagacg ctgtgacaaa tacgtctttc
    36841 atgtccaaac aaatcgaaac gcaagaagaa tcaatggcga acttagactc ggttgtctta
    36901 atctttgtcg tattatcagg actgctggct tttatcgtct tgtataatct aactaatatc
    36961 aatatttccg agcgtgtacg cgaattatct acaataaaag tccttggatt ttttgataaa
    37021 gaagtcacga tgtacattgt tcgagaaaat atcatcttta ctcttttagg aatcatcgga
    37081 ggatttggtg taggatatat attgactgac ttcatcttgc aacaagcgtc tatggagaat
    37141 gtcatctttc cattagtgat cacatggtgg gcttatgtct tatcagcagg attaactatc
    37201 gtatttacgg ttattgtgat gattgttacc catttcaaat taaagcatat cgatatgatt
    37261 gatgcgttga aatcgaatga ataaaaacag aggttgtgaa atcagcggtt tgacctgagt
    37321 attagagaaa caaacggcaa aatagttttt catattttgc cgttttttga gctaataccg
    37381 aaggacagct gattgaacac catgaatcag aggttgtaaa aaagccgtcc tgcatcgagc
    37441 aaaaagaata ctcaaataaa attagctcct catgttttac atttgagaag actgattgcc
    37501 gtagataaaa gcttttgaac accatttata gaagaaacaa gaatattttg ctattttaaa
    37561 caagaggata gacaaataca tgtctgatct cttgtttttt attgggcaac agacctctta
    37621 gaatgtataa agataaattt tacaaacgct ttcggttcag ttataataat aaatgataac
    37681 ttgtatatat aagttgtggt aggtaataaa tcagttgaat ggaggtaaat atccatgaca
    37741 tttaaagaca aagtcattta ccaaatctat cccaaatctt acaaagacag taatggtgat
    37801 ggaattggag atttaaaagg aatcaaagaa aaactcccgt atctgaatga tctaggcatc
    37861 gacatgattt ggctaaaccc tatttatcca agccctcaaa aagacaacgg ttatgatatc
    37921 tctgattaca cagccatcga tcctatcttt ggtacgatgg aggaattcga acagctaata
    37981 gccgaagcaa agaaataccg gatagaaatc atgctcgata tggtgctgaa tcacgtttcg
    38041 acagaacatg aatggttcaa aaaagcacta gcaggggacc agcattatca ggacttcttc
    38101 attttaagag aagagccaac ggattgggta tcaaaatttg gtggaagtgc ttggtcgcca
    38161 tttggagata cggggaaata ttatttgcac ttatatgatc ggacacaagc tgacttgaac
    38221 tggcggaacc aagcagtaag agaggaacta ttcaaagttg ttcgtttttg gatggaaaaa
    38281 ggggtaaaag gattccgttt cgatgttatc aatgttatcg gtaaagacga acaattgaaa
    38341 aataataaag aaaatgatgg caaacctgaa tatacggaca aaccaatcac ccatacgtat
    38401 ctaaaagaat tgaaccaagc aacgtttggg acggattcca ctatcatcac agtcggtgaa
    38461 atgagctcta cgacgatcga aaattgtatc ttgtatacag aacctagtag agaagaatta
    38521 tcaatggtct ttaatttcca tcatttgaaa gtcgattatg aaaatgggaa taaatggtct
    38581 actcctccat ttgattttgc agaattaaag cgactatttc atacatgggg agaaaagatg
    38641 agtgagggta acggctggaa tgctctattt tttaataatc atgatcagcc acgtgcgctc
    38701 aatcgatttg tagctatcga tcagtatcga aaacaaggag cagagatgct agcaaccatg
    38761 atccatttga accgtgggac gccctatatt tatatgggag aagaaatcgg catgatcgac
    38821 ccagactatt catcgatttc cgactatatt gacgtagaaa gtttgaatgc ttataagtta
    38881 ctccttgaac aaggattcac agaaaaagaa gcgtttcgtc ggatcaaagc aaaatctcgc
    38941 gataactctc gaacacccat gcaatggtca gacacagaac aagcaggatt tactacaggg
    39001 aaaccttggt taaaagttgg aggcaagcta gaagagatta atgtagaaaa agaactatct
    39061 tctgaagatt ctattttgtc ctattacaag aaattgattc ggctgagaaa aacatatcca
    39121 atcgttgcac aaggagatta tcatgcttat gaagcaaatc atccggaagt ttatggcttt
    39181 cttcgccaat ttgaaggaca gcagctgctt gtattaacaa atttctatga taaagataca
    39241 aggatcgcca tcccagaagg attcacagaa gccaatattc ttatcgataa ttattccgat
    39301 actgttcttc atcaaagtct ggagctaaaa ccataccagg caattgcttt gctgaaaaat
    39361 taaaacaaaa acacaaaacg tcgttcctac gagctattct cgtaagatcg acgttttgtg
    39421 ttttatttaa aataatcttc ttcagaaaat gaagagtttt catactctcc tttatcgcca
    39481 taaaatttat tgtagcgttg tttgaattta cggaaaataa aagtaacgag taatttgact
    39541 aacgtataga taggaatacc aaaaataacg cccacaattc ccattagatc acccatgaca
    39601 agtaaaacga ttaagatcgt aatcggatgg atctgtaaac gatcacccat tactcgagga
    39661 atcaccaagt caccgtggag aagttgtacg gcaaaccaga caatgacaaa tttgacagcc
    39721 ataaaagtag agtcttggaa tgcaatgatc aaacctggaa agaaggcgat aaacggccca
    39781 atatatggaa tgatacataa caacccagca gaaatagcta aaacactagc aaattctaat
    39841 ccgatcagta agaaacaaac ccagtagact gctccaagga taaatgaagc aatgatttgc
    39901 ccctttagaa atgaacccaa ttgttgatta gcaatctttg tcaaattttt aaaatctgta
    39961 cgaaatgctg gtgggacaat cgctaaaact gactgataaa atttttgagg atctctcaaa
    40021 aggaaaaaag cgacaattgg accagtaaat aaagtaataa aaatagctgt aacagttgaa
    40081 aaaatgttgc tgatccgttg tgcgccactt tcccaataat ttccaataaa tccagctata
    40141 tcagacgtca cgtcgtcaat agaagcgaaa aattgattaa atgaatcggc aaaaggtgtt
    40201 ttctccaaaa attgtcggag actctcttga aaatcttgaa acaaatctgg caaactactg
    40261 atcaatgtct ttgcctgttc ttcaagaaaa ggaataagcc atatgcttcc aagccccaat
    40321 aaaaataaaa taatcacata aacgataatg actgacaagt tcctcgaaag gtgcttgctc
    40381 aaacgtttga tgactggttc caaaagataa tacaagatca gtgcaaacaa taatgggggc
    40441 aagatagtag cgataatgat tccgacaggc ttgaatataa acgagatctg atggaaaaaa
    40501 taaatgatca gcgcaagtaa gataactatt cctaaaacat agtaagaggt ttttcctcct
    40561 aaaaagcgga tcaaacgatt cgttgtatct gtttcttttt tcactctttt tcctccttta
    40621 tctataactt cattatagac aaaagcgggt ataaaaggaa aatgatagag gttgattgca
    40681 aaaatatcgt caatcattca tataaacttt ctcatcaatt aaaataagaa aacgcttgac
    40741 agttctttta accatatgat aaattaaatc ctgttgctaa aacgtaacta ttacggtttg
    40801 cgaaaagcga atcggaacat tcaaatgaaa gaagatgaga agaggagtgt cataaatgaa
    40861 acgattgata ggtatattgg ccatgctggt tttagcaggt atgttaactg cttgcggggc
    40921 aagtgggaaa gccgaggaca gtaaagaaaa attgagcgtg atgacgacct tttatcccat
    40981 gtatgatttt acaaaagcaa tcgtcgggga tgaaggagaa gtagagttat tgattccagc
    41041 agggactgat tcccacgatt atgaaccttc tgctaaagac atggcaaaga tccaagatac
    41101 agatatcttt gtttataatg atgaaaacat ggaaacatgg gtccccgcaa tccaaaaaac
    41161 attacaagaa ggcaatgtcc atacgataaa agcgacagaa ggtatgcttt tacttccggg
    41221 aagtgaagaa ggacatgatc atgaccatga acacggggaa gaaggccata cacatgagct
    41281 agacccacat gtatggctag ctccaagttt agcaatcaag caggtagcaa acatacgtga
    41341 tcagctgatt gaagcttacc cagaaaaaca ggaagtatgg acaaaaaatg cagcagccta
    41401 taccgagaaa cttcaagcac tccatcagct ttatcaagaa acctttaagc aagcaaaaca
    41461 aagatctttt gtcacgcaac atgctgcatt caactatcta gcgttagaat atggattgaa
    41521 tcaagtatcg attgctggtc tttcttctag tgaagaaccg tctgcggcga gaattgctga
    41581 actgaaacac tttgttaaag aacatggaat caactatatt tattttgaag aaaacgccaa
    41641 agatagtatt gccagaacgt tagcaaacga agcaggtgta tctttagaag tattgaatcc
    41701 tttggaagga ttgacgaatg aacaaataga aaatggagaa aactatcttt ctatcatgga
    41761 agcaaacctc gaagcgttga aaaaaacgac agagacagaa aacccgctag aagatacttt
    41821 gacccccaaa aaagaaaaga gcgtctacaa cggttatttt gaagacgagg atgtacaaga
    41881 tcgctctctt tcagattggg caggaacttg gcaaacagta gatacgtatg tagaagatgg
    41941 gacttttgat cctgtttttg aatataaaga aaaattgaat caggataaga cagcacaaga
    42001 atataaagaa tattatacga agggctatca aacagatatt gcttcaatca agatcagtga
    42061 gaaagagatg gcatttacgt ttaagaatgg aacaacgaaa cgttcaaatt atcgttatgt
    42121 agggaaagaa atcttgacct acgaggcagg aaaccgtggc gtaaggtatc tattcgaagc
    42181 agaagataag gaaagtggcg cttttagata tattcaattc agtgatcaca cgattgcacc
    42241 ggctgactcc gaacattttc atttatatgc aggaaatgaa agtcaagaag tattgctgaa
    42301 agaaatggag aattggccaa cattttatcc agatacaatg gatggacgtg aaattgcaca
    42361 ggaaatgctt ttgcactgat aggcaaaaaa gaaccgaagg gtttggatcg gctggtcatt
    42421 tagtcggtcc aaactattcg gttcttttta tgaaatcaat ttctttaatc cacggataga
    42481 ggctgggatg gtctcgccgt ttgccaacgt gacttctctg gtttttttat taatcgaccg
    42541 cacattttgt gtattgataa cataggattt atgacaacgg ataaaattcc gatgcatttt
    42601 ctcgatttct ttgatcttct catagaattg taattgggca tgagtcaaat ggacttccag
    42661 tttatgtggc gctcctagcg aagtagaaaa atattggatg tctttgatcg gtaaaaattt
    42721 gatctcatca ttaaactcta ttttgaagat atctttttgg atttgggaca tttgaaaatc
    42781 ttcgaaaatt ttgctcagga tatgctcgac attttctttt aaatcataaa gatcttcttt
    42841 gacgatataa tcagtcggtt cgatgttgct ttttaagatt ttcatcgaca tttccgtatg
    42901 ggaagtcaca tagattattt ttcctaaagg atctaattca cggatcaatt taccgatcgc
    42961 tacaccatcc atttcactgt cttctagttc gatatctaaa aagtaaatac caaaagaaga
    43021 agttctgatc ttggctgcat tgagaagttc ttccggatca gaggtagaaa tatggacata
    43081 actgtctaag ttttcaatca tgattctatt tttgatcacc gttgataaaa cttctaattg
    43141 ttttggatcg tcttcacaaa tataaatggg aatcatatca ttactccttt attttatttg
    43201 tatataaatc gtttgagaaa aacgctggtt ttcaattgat gtttcaagga aaagataagg
    43261 attggtcttt gtcaattcat ccaagataaa caagccaagg ccttcgtttt ttggatttgt
    43321 ttttgttgag aacccttttt gtttcaactg gtttaacggt aatgtatttg ttgttgtatt
    43381 gatcacacga atcatcacgg aatgattctt cttgagtatg gtcaattcga tttttttctt
    43441 ctttgcagca ctagctcctt caatcgcatt gtccaagata ataccaagca tacgtacaag
    43501 gtttaccgta tgtttcgtat ccagttcgat tggctcagga aaatgaagct ggacgatcaa
    43561 ccctttttcc tgtgccatca tgagttttaa tgacagtaaa ctacggatct caggaacttt
    43621 catattatcc aacatactta gattggccgg aaaaaggttc atcatctggc gtgtaggtaa
    43681 tatcgtttga tcataataag accgtaatcc ttctaagtcg ccttctgaaa tatagctgtg
    43741 aagagaaaaa agcagatttt ggtaatcatg tttgaattct ctcaagtctt gatagttttt
    43801 ttctagatct ttgatataat cctgttgcat cctgacttgt tgctctaata actgatcagc
    43861 taatttctta ttagagattt tccaataata aaccaagatg atcaggccaa cacacagata
    43921 tagaatgaaa aaactcgtat tcaaagctaa gacatcaggt gtttcaccag aaaaacgggt
    43981 ataaaaaata atgatatagt atgtaaataa tatcaatgtc ccgatcgtac cgatcatacg
    44041 gcggtccaca gtgtgaaacc aagtctctaa cgattttttt aaacaaaaag ctaataaagc
    44101 agataaaaaa gcggataaga caatgtgaaa atactgcaat gaatctcctg gttcaataac
    44161 cgaagatttc aaaacaaaaa aatcgccgat gcttgttaag tgatctccta aaagcgacgt
    44221 caataaccca aaaggaagcg cgtaaaccaa ttgttgacgc gaagtcgaaa agaagaaaaa
    44281 agtaagcatc agcattccta tagcaattag agcagtaaaa atccctaaaa tcgaatagac
    44341 ccatccaatc aaaatacaag aaatcagaat gactcccgca aacagatatt tgtatcggat
    44401 gtgatggtca atcaataaga tacaaattgt gtaaatcaaa tattgcaacg ctatggacca
    44461 taaaaacata aagtacagct cccattgatt tttaccaaat tatagcacaa ttggcgtatt
    44521 atttttttaa tttttcaggg attttgaatt cagaactcat accaaagcag cagccagata
    44581 caaaaaagtc agataagtta gttaattgtt taatgattgt ttttttcatg aaagattcct
    44641 ccaaaattca tcaagtagtt tgtaatagga agcaacgtag ctatttctaa aacaatccca
    44701 agtagcaaat aggtagaaaa gtaagaagct gagaaaaata acgtaatgag agaaaaaatt
    44761 agaaacatgc tgatcgcctt ctttaataat gggggacgtt tctcgggttc aatgggattg
    44821 attgctgtac ctcttgatcc atagcgaagc agtaacaaaa agcagctgat taacaaaaag
    44881 accatcattg ggaaggagat agtcaattgc agatgtttca tcaccaaggg aacgccccat
    44941 aaataaagta gtgtccacag cagacaaacg aattcagagt cggaatgcaa tccataagca
    45001 tatctgcgga tgcagatata agaaagaaag gtgattcctg tttccgccca tgagcctgtc
    45061 accagagaaa agactagaac gaccgctagt tttccaagat tattcaataa aacttctaag
    45121 acaaatttta cttggacata caccatatct tcttccgatt tgtctccgct gaataaggct
    45181 tctaataatt tgttcacaac tttatctttc atctcatacg tacctccacc acaaatttta
    45241 tgctaaaaaa aataaaaaac gtcttttgtt tcataaaaag tggttttgac atcaaaaccg
    45301 tcatgatctc ctaaaaaaat cttcgttttc caagaacctt accaaaaaaa gtgacagttt
    45361 tgatacgaaa agtacttttt atgacaagtt tgtgcttttt cgagtgattt atgttaaaaa
    45421 attactgacc ttataaaagg tgatggaggg attcttatgg aaaatgaaca attgtttgaa
    45481 gtcggcgaaa catatgcatt taaatctgat ttatttgaat caccaataaa aggaaaaata
    45541 gaaaaaatct atgaaaatag tgtgatgata cgtgtcatga aatgcgcagt agaagacaat
    45601 gataccgctc ataatctgca ctggcagtta gttgtacgca aatcaagtac aatagaagaa
    45661 taaaaacaga taaaatgttg agagcataaa gaggttgtga gtctcccgtt tagctctgag
    45721 ttacaaggaa taatgttaaa aaacagcttt tcatgtttta tgaatattgc cttgtgaccg
    45781 aggtgttggc aggagaatac tgtttatttg aaaaaagggc tgcgacaaga cttttgtcac
    45841 agcctttatt ttcatgaata ggagttactt ttggctactt ttagagaagt agcttttaag
    45901 gagcagataa agtcaaggct tttatttcta taaatgaagt agtaaaatga agaacagatt
    45961 ttattacagg aaggatgccg ataattgtga tcattgttgc aggaacgatc ggtgcaggga
    46021 aaagcacact aactgaaatg cttgcccaag atttagaaac aaaacctttt tatgagaacg
    46081 tggaagataa tgaagtattg ccgctatttt attctaatcc agaaaagtat acttttttat
    46141 tacagatttt ctttttgaac aaacgctttt tggcaatcaa agatgctttc agccatgatg
    46201 acaacgtact agaccgctcc atctacgaag atagtatgct gtttcatttg aatgcagatt
    46261 tagggcgtgt ttctgaagta gaagtaaagc agtatgaagg tcttttagaa acgatgctga
    46321 aggagttaga agaaatttcg ccacaaaaga aaccagatct actggtttat attcgtgtat
    46381 cctttgaaac tatgttagcg agaatcaaaa aaagaggccg ggaatatgaa cagctagaac
    46441 aagatcctga actctattcc tactataaag aactcaatcg acgatacgaa gagtggtatg
    46501 aacagtttga tatatgtccc aaaatagtga tcgatgggga caaatatgat ttcgtagccg
    46561 atccggcatg tggagaacaa atcgtacaag aaatcaagat gcgggcaaag aaaatgacag
    46621 aagaggcaga tgcccagtcg atccgctaca ctacaaataa cccgaaagca aagggaatct
    46681 ttacaactaa ataatataaa aactaagcaa attgctcact cgcagatatt tctctgtgag
    46741 cagcatcttg cttagttttt ttgattcatt gagatcaaat agtgaaccga ttcgtatgat
    46801 aaaattgcca taaatgaaat gtctgagtga gggccatgat caaaaataaa atggaaacga
    46861 tcaaaatcga atgggcgcca aacagatgat gacagaaaac aaggacaata gctcctgcga
    46921 taaaggcaag aacgacactt agatagtgga aaaatcgatc aaaatctgct ttttctttag
    46981 aaatacaata atcatataag ttcgttgcta ccccttttaa atttccagtt gtaaataaat
    47041 tagtgtaggc acgcccgttg attttatcaa aagctaccca ctggatcgat gcagtaaaag
    47101 caatcaaaat cgttactaat gcgggatgct catggacggg tgtcaaacta acaaagaaaa
    47161 aaatcactgc ttcataatat agaacaaaca agcgccagaa atgtttttct ttttttctaa
    47221 aataatcaat tagatacttt gttagaagaa tccctaagaa aaagaaaagg gtagacaata
    47281 cttttttacc aacacttagc cattctccgt caaatgcttg gatgatcgat agaatgatat
    47341 tgccagtttg agcagaggca aaagcaccat attggatata agtataactg tccatggctc
    47401 ctccgataaa tgtcagcaaa agtcctattg tacgcccctc gtgaaaggaa gtctgcattt
    47461 ttttcatcac cttttatgaa tatttttgtc ttccttatct tagcataaac gattgaaaaa
    47521 aaaggaaaaa ttttcagaaa actaaaatca tatcgcttcc cattttcatt tttagaaagg
    47581 tctgttagta taaagaaaaa atagacaacg aaactttaaa taaccaactt gaaataaaca
    47641 aattcaaaga agaaagatgg gaaggaaatc aatcagttga atgaaaaaga aattctccga
    47701 ttacaaaaag aattgaaacg ctgggagaac aagtataaaa agcttcaaca agtctttcgg
    47761 ctacaagaag aaatcattgc tacctatgaa gcggcttatg gcgaagcacc cggacttatt
    47821 gaggaagaag tacaagtaaa agaaagtgaa ggaaacagct ctttctttaa aatgatggag
    47881 aaacgttcct ataatcgctt caatcaagaa caaaaagcag ctatcacata tgatatgaag
    47941 aaacatcttc gaatcatagc aggagctggg agcggcaaaa cgcaaacaat ctgtgcaaaa
    48001 gctgtttatc tgatgacgca aaaacaagta gacgaagaac gcatactaat gatcactttt
    48061 acaaggaacg ctgcaaatga actaaaaaaa cgagtagata atttcagcca gagaaaaacc
    48121 gctgtccata tcggaacatt ccatagtatc ttttttagga tatacaatga aatttgtcga
    48181 aaatttcctg aagtagcaat gcaaggaata caaggagact tttcaaagga tactgcacaa
    48241 aaagtgaatg ctgttttgca acagctgata cgtaaatata atctttatat atttgatcaa
    48301 tatggagaaa aaacgattgc ttctcggtta gactattggc agaatatgaa cctttcagta
    48361 gaagaaatgg ttcagttagt taaagaaaaa tatgattcca ttgataagaa tgcacgacag
    48421 ccgatatcag aacgactgta tggattgctc acggaactcc aagaacaaaa aagaagccag
    48481 caattgctag agttcaatga tgtactccaa aatctgaaaa gcgctttgga gaatgaggag
    48541 atccagcatt atatcggcca aaaatatgat tatctattca ttgatgaatt tcaagatact
    48601 aatccacttc aatgggaaat cgtgaaacgg atgacaaagg aaaacaggat caagttgatt
    48661 gttgttggag atgatgatca gagtatctat ggattcagag gatcagagcc agcatacatc
    48721 aagaactttg aaaaagaata tcctaccaaa actcttttct tattaactaa ttatcgttct
    48781 cgggcagcta ttgtccaagg agcaaataga ttgatcagct ataataaaaa tgatcggata
    48841 ccaaaggcga tgattccagc acaaaaagaa gcaggtgtta tggaagccta tttgttttct
    48901 gatactaaag cagaaagtca gtggctaatc aaacaaattc agacatttat tcaaaaaaat
    48961 gggaaatata aggaatcaat catattatac cgatcagctt cacaaacgca gcagcttgtc
    49021 caatctctgc tgaaaacgaa tattcctttt gtactggaag cagatagtcc atatgaaggt
    49081 atctttggta tcaagtcttt ccaacatttc tatcaaaaaa ttgttcattg gcaaacagca
    49141 ctgaatctgc aaaagaaaaa tcaggcctac cagcaattgc tccggcagct gatggcagac
    49201 tgctacctga aaaaaagtga atgcgatcaa tacttttctc ctaaatatca aaatatagcc
    49261 gttgcagatt atattttgtc gataagcccc aatttaaaat cgaaatctgc agaaatccga
    49321 gagtttgagg aagcgttgcg taaaacagac cagcatcaag aaatctattc gcttgttcaa
    49381 agctatcttc atctgccacg tatagctaag gaaatcgacc agagtgatca agaatggata
    49441 cgagaagaag taaagcagca tgctactttc agaagactcc aagccttatc gcaagaaacc
    49501 caagcgacag ctaaagaatt aaaaacccgc ttgattgctt acagacaagg aaaacttgat
    49561 gcactatgta tccagagcat tcacaaaagt aaaggtctta gttaccgaaa tgtctttttg
    49621 attggttgta acgaaggaag tttgccttat aacggagcga cagaaaagaa agtaatcgac
    49681 tttaatgaaa taaaagcaga accagtaacg acgatagaag aagaacgaag actattttat
    49741 gttgcgatga ctagagcaag aaatcgtctg tatctatgtg tacctcaaat gaaaaattca
    49801 agaaaattga aagtatcgag atttatcaaa gaaaccggga gtcgtgtgaa aaaaggaaag
    49861 tgatagaaga gagggtgtga cagaagtggt cagtttcaag aaagaagaag gaatgtacga
    49921 aaattgcttc tcaaattttt gtgaaatttc agcttatttt cgaagaagct atttctggaa
    49981 cacagtttat tcggaaaagg gaggtgtgac aagaattttg tcacacctcc cttatttatt
    50041 ttgaaaatga gaatactatt atcaaaatag agaatatata gaaaaattct cattattcaa
    50101 acgtaaataa tcagttattt tgattttttt tatattttat tagctaataa ttggtatttt
    50161 aaaagaaatt actgtagaat tggattataa ttaaaaagga gtgagaaaat gataaaagta
    50221 tatacttcgc ctagctgtac ttcctgtaga aaagcaagag catggttgaa agcgaatcaa
    50281 cttgaatttg aagagaagaa tatttttgcc gaaccgttaa cagaaagtga gatcaaaaag
    50341 atcttggcag cgactgaagg aggagttcaa gatattattt ccactcggtc gaaaatttac
    50401 gaaaagctgg gcatagattt taacgaatta actttaaagc aaatgatcgt cttattcaaa
    50461 gaatatcctt cattattgag acgacctatt ttgattgatg aaaaaagaat actaatcgga
    50521 tttaatgaag atgagatccg gtcatttgtc cctcgtgaaa ttcgatgtgt tgccagaaat
    50581 ctgatctatt tacaaaacaa taacatctta aattcatagg gagggagcct tcgtggaagt
    50641 gaaagtctat ggatcagcgc actgtgtaac aagtctgaag gcgaaacaat ggttagaaca
    50701 ccatcaattg ccttatcaat ttgttgactt agaagaacgc gatttaagta cagaagaagc
    50761 agaagaatta tgcagttttg aagaagtgca agcagaacag ctatttgcga cttggtctga
    50821 ggcttttcac aacattgcga ttgacctttc ctgtgtagga aaaaaacaac tgattttttt
    50881 atgcacacaa cataccaatc tcctcagacg tcctttgatt attatcgatg aagttctatt
    50941 tattggatac aatgagcagt tgatggaaca gcttatctta aataaataga ctttaactgt
    51001 tttaatcaag tcactgagca tttcatacag ttgtaacagt cgaacactta gcatcaagcg
    51061 tgttatgtgt tctttttttg actttatttt tctactatag agacatgctc aatttatgtg
    51121 gtcaaaattc aaatctaggt ggggatatag agttaaaaat atattgacat gtgtaaattt
    51181 acatgatata ttcatttctg ttgttttaag tagcaaagca ataaaatagt attttaaaaa
    51241 acatataaaa tagttgttga catgttagaa atgacatgat aagataactg agttgttaaa
    51301 aaagaaccac ttgtgaagct tgattctatc gaaaaaaact tcaaaaaagt tcttgacaaa
    51361 taacaaatga taagttatga taaatgagtt gctgtaagat ttcgaaaaac gaaatcaaaa
    51421 aaacttttaa aaaagagttg acaattactt gtctctctga tatgatataa aagttgctac
    51481 ggcagccaaa aacgaatcgg ggaacactcc tgatgaagta gacctttgaa aactgaacaa
    51541 agtaagacaa accaaatgtg tagggcgtct tgattcaatt caagacaaca aaca
//
LOCUS       DADGKS010000015        51099 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.015, whole genome shotgun sequence.
ACCESSION   DADGKS010000015 DADGKS010000000
VERSION     DADGKS010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51099
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.015"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(372..1958)
                     /locus_tag="JXV47_000937"
     CDS             complement(372..1958)
                     /locus_tag="JXV47_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HAX1486996.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
     gene            2209..2433
                     /locus_tag="JXV47_000938"
     CDS             2209..2433
                     /locus_tag="JXV47_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HAX1486997.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            2575..4326
                     /locus_tag="JXV47_000939"
     CDS             2575..4326
                     /locus_tag="JXV47_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAX1486998.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLAPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAALLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGCSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQKLEAKIEGGEA"
     gene            4326..6110
                     /locus_tag="JXV47_000940"
     CDS             4326..6110
                     /locus_tag="JXV47_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1486999.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPTITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLTKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            6568..7419
                     /locus_tag="JXV47_000941"
     CDS             6568..7419
                     /locus_tag="JXV47_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAX1487000.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELYQVIQKKYKDTFGCVEKIADFLAEIFNYQMSTDEKMYLTIHIARL
                     VHENRCK"
     gene            7516..9402
                     /locus_tag="JXV47_000942"
     CDS             7516..9402
                     /locus_tag="JXV47_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1487001.1"
                     /translation="MGKYQELASKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGVVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTALLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPAFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNPGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSEAGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEEEGYSLETPVIVTNYTDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(9443..10345)
                     /locus_tag="JXV47_000943"
     CDS             complement(9443..10345)
                     /locus_tag="JXV47_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAX1487002.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            10575..11978
                     /locus_tag="JXV47_000944"
     CDS             10575..11978
                     /locus_tag="JXV47_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAX1487003.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPTMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMNELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            11978..13411
                     /gene="ascB"
                     /locus_tag="JXV47_000945"
     CDS             11978..13411
                     /gene="ascB"
                     /locus_tag="JXV47_000945"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAX1487004.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFPV
                     ITGKKKMFEFDENHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            13556..14482
                     /gene="trxB"
                     /locus_tag="JXV47_000946"
     CDS             13556..14482
                     /gene="trxB"
                     /locus_tag="JXV47_000946"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HAX1487005.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            14695..16422
                     /locus_tag="JXV47_000947"
     CDS             14695..16422
                     /locus_tag="JXV47_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HAX1487006.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     TIIQKMTEE"
     gene            16495..16788
                     /locus_tag="JXV47_000948"
     CDS             16495..16788
                     /locus_tag="JXV47_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAX1487007.1"
                     /translation="MPDTQKTKVEKVSQLFKMLSDPTRLKILLYLKDGEQNVTAIIQA
                     VEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHVLDILNQTLKHVEHQ"
     gene            complement(16872..17732)
                     /locus_tag="JXV47_000949"
     CDS             complement(16872..17732)
                     /locus_tag="JXV47_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HAX1487008.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPSVEFNLFRRT
                     FVTDEKTLMQALQDALEEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            17824..18252
                     /locus_tag="JXV47_000950"
     CDS             17824..18252
                     /locus_tag="JXV47_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAX1487009.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            18414..18590
                     /locus_tag="JXV47_000951"
     CDS             18414..18590
                     /locus_tag="JXV47_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HAX1487010.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            18617..19063
                     /locus_tag="JXV47_000952"
     CDS             18617..19063
                     /locus_tag="JXV47_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HAX1487011.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(19219..20598)
                     /gene="brnQ"
                     /locus_tag="JXV47_000953"
     CDS             complement(19219..20598)
                     /gene="brnQ"
                     /locus_tag="JXV47_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAX1487012.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            21304..22275
                     /locus_tag="JXV47_000954"
     CDS             21304..22275
                     /locus_tag="JXV47_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HAX1487013.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            22299..24491
                     /locus_tag="JXV47_000955"
     CDS             22299..24491
                     /locus_tag="JXV47_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HAX1487014.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            24508..24984
                     /gene="ybeY"
                     /locus_tag="JXV47_000956"
     CDS             24508..24984
                     /gene="ybeY"
                     /locus_tag="JXV47_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HAX1487015.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            24962..25363
                     /locus_tag="JXV47_000957"
     CDS             24962..25363
                     /locus_tag="JXV47_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HAX1487016.1"
                     /translation="MPMDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFG
                     ILALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKD
                     MAAGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            25378..26277
                     /locus_tag="JXV47_000958"
     CDS             25378..26277
                     /locus_tag="JXV47_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HAX1487017.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            26420..27232
                     /gene="recO"
                     /locus_tag="JXV47_000959"
     CDS             26420..27232
                     /gene="recO"
                     /locus_tag="JXV47_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HAX1487018.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKSGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            27616..28533
                     /gene="glyQ"
                     /locus_tag="JXV47_000960"
     CDS             27616..28533
                     /gene="glyQ"
                     /locus_tag="JXV47_000960"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HAX1487019.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            28535..30610
                     /locus_tag="JXV47_000961"
     CDS             28535..30610
                     /locus_tag="JXV47_000961"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HAX1487020.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEIIPFEILDVKTDRASRGHRFLGEDVTFTHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKNHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            31000..31779
                     /locus_tag="JXV47_000962"
     CDS             31000..31779
                     /locus_tag="JXV47_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487021.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKNFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISAAYATKAQTVAQQMGYSNISY"
     gene            31825..32769
                     /locus_tag="JXV47_000963"
     CDS             31825..32769
                     /locus_tag="JXV47_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAX1487022.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTLQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            32785..33564
                     /locus_tag="JXV47_000964"
     CDS             32785..33564
                     /locus_tag="JXV47_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HAX1487023.1"
                     /translation="MEETISLKEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDALGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            33576..34274
                     /locus_tag="JXV47_000965"
     CDS             33576..34274
                     /locus_tag="JXV47_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HAX1487024.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAR
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILDEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLNKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            34302..35066
                     /locus_tag="JXV47_000966"
     CDS             34302..35066
                     /locus_tag="JXV47_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HAX1487025.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMTASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPDYEEVKKKKFGLF"
     gene            35080..36897
                     /locus_tag="JXV47_000967"
     CDS             35080..36897
                     /locus_tag="JXV47_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008378780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAX1487026.1"
                     /translation="MFILTRRRKIATLVFVDSLLLIAANIAAAKFMKPFVSIPMDLIL
                     ISIGLSIGFYLFYGSLFKVFTRINRYTNLREIIAIFSSLSASAASSILILLFINRRYS
                     LRLVIFAYLLSLLLIIGSRLIWRIYIETKNMRYVSADSAKNTLIVGAGEGGRILYNSF
                     LGSKTAQDIHVVGFVDDDPNKRNTYLSGKKVLGALKDIPELIEKYDIQMVTIAIPSLS
                     RKKLRRIFELVESARVKVNTMPSIEELASGKISVSKLKTIDVVDLLGRDEVKLDIESI
                     KDQITDKVILVTGAGGSIGSEICRQIIQFNPAKLLLLGHGENSIYLIDRELRTHHQNC
                     PTEIVPIIADIQDREKINEIMEQYHPDIVYHAAAHKHVPLMEYNPKEAVKNNIFGTKN
                     VAEAAKAAKVKNFVMVSTDKANNPPNVMGSTKRIAEMIVTGLNEEGCTKFSAVRFGNV
                     LGSRGSVIPVFREQIAQGGPITVTDFRMTRYFMTIPEASRLVIQSGALAKGGEIFILD
                     MSEPVKIVDLAKNMIRLSGYSEDEIEIIETGIRPGEKLYEELLLDKERNDEAVYEKIF
                     VGNIKGYSIQKVMDFVKSLPQDDEQLAKDIVTFANASNR"
     gene            36951..37874
                     /locus_tag="JXV47_000968"
     CDS             36951..37874
                     /locus_tag="JXV47_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HAX1487027.1"
                     /translation="MNAFKTALNNNEMEGKIIGADCSELAPALYMCDEKIVLPKVSES
                     NYIEELIKVIKFFEIKLIVPTIDTELSTLSRNKKYIENETDSVVLVSSEKVIDICENK
                     ILTSAFFEQNGFKTPEILNSSEITKFPVFIKPLNGSSSVNTFIVNNEKELLFFSEYID
                     NPLIQEYILGEEYTIDVCLNFDSTPVSIVPRKRIATRGGEILKGQIIKDRELIETTKK
                     MLEKLNAIGHITIQCIKNEKGIFYLEINARYGGGAPISIKSGANSPEYIIKMIDSKKN
                     LRYRENYLDKMIALRYDQAIYLDEKGNVYND"
     gene            37846..38562
                     /locus_tag="JXV47_000969"
     CDS             37846..38562
                     /locus_tag="JXV47_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HAX1487028.1"
                     /translation="MKKEMYIMIKAVIFDLDDTLVSEYDYVKSGYKCVARRLAVQKIF
                     PATFDEIYRVLLDLFAEDSKNVFNRLYDYFEIPYSKKEIKELVNVYREHKPDINFLEN
                     ADTLLTELRSRGYKLGIITDGYAITQRNKLDALKVDYLVDYICITDELGRELWKPHPI
                     SYLLLLEKFNLKAQECIYIGDNELKDFITAKSIGMQTIKIERVNGIYRESSLKFKRFY
                     QADKKIRSLWEIKNFLGVIS"
     gene            38559..39677
                     /locus_tag="JXV47_000970"
     CDS             38559..39677
                     /locus_tag="JXV47_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HAX1487029.1"
                     /translation="MKSKRILLASPHMSEEGYEKEYVKEAFDTNWVAPLGANVNGFEK
                     ELAEYVGASHAAALSSGTAAIHLALKAAGVGKDDIVICQSLTFSATANPILYQGAIPV
                     FVDSDYETWNMKPEHLRTALEKYPNTKAVLVVHLYGLSANLDEITKICKEYDVTLIED
                     AAESLGTTYKGKYTGTFGDYGIYSFNGNKIITTSGGGMLVSNDKEKVEKVRFWATQSR
                     EKARHYQHNEIGYNYRMSNIVAGIGRGQLKVLNERIEKKRYIHSFYKKELSKLSNIQF
                     MPENNWNEPNYWLSVITIKGINANHLIDELDKNNIEARPVWKPMHLQPVFKNYDYIGD
                     DVAETLFDLGVCLPSDTKMTDEDLKYVVSTIKRVINDA"
     gene            39670..40287
                     /locus_tag="JXV47_000971"
     CDS             39670..40287
                     /locus_tag="JXV47_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAX1487030.1"
                     /translation="MRKKTFYQLFGKRILDILLSGIALIVLSPIILIVGFLVRIKLGS
                     PIIFKQERPGKSEKIFSMYKFRTMTDERDHNGEYLPDEIRLTKFGKMLRATSLDELPE
                     LWNILKGDMSIVGPRPLLVEYLPLYSEKQRKRHNVRPGLTGLAQVNGRNAISWEEKFD
                     LDVYYVDKISFFNDLIIIIQTCKKVIKKENINTINNNIPEKFKGS"
     gene            40414..41583
                     /locus_tag="JXV47_000972"
     CDS             40414..41583
                     /locus_tag="JXV47_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAX1487031.1"
                     /translation="MCRVLNILFQYEKIIKKYKEKRVMAKYYNKKILIMANNDDGLYR
                     FRGMLIKNLVDQGNEVIVSLPKGKNIPKLIELGCQIIETPIDRRGINPKTDFKLFFNY
                     CNILKKIKPDMVIAYTIKPNIYGGLACRLRKVSYALNITGLGTAFQKKGVLKSLIVFL
                     YRLAAKKSKVIFFENFENMKTFQTLQIAKQSKYKLLNGAGVDVEHFSYLEYPKDEQVH
                     FLFIGRIMKEKGVDELFEAMKNLYSEEKNCVLDVLGYFEEDYGIKIEKYEKEGWLKYH
                     GYQSDIRPFVERAHCFVLPSWHEGMANTNLESAASGRPIITSDIPGCKEAVIESKSGY
                     LCERKNSCSLYNSMNKFLKLSYEQRINMGKMGRNYMIKKFNKKKVVDETIKSLFS"
     gene            41590..41985
                     /locus_tag="JXV47_000973"
     CDS             41590..41985
                     /locus_tag="JXV47_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAX1487032.1"
                     /translation="MFCKVCDRKEGFCGFRIDIKELAKVSDIFLFTTLQEGMPRSMME
                     AMASGLPCIASKIRGNVDLLVEGKGGYLVPAKDAELVAECLRELINNKSLRKYMGNEN
                     LSRIKEFEVSIVKKRIKEIYEEVIGESVK"
     gene            41982..42983
                     /locus_tag="JXV47_000974"
     CDS             41982..42983
                     /locus_tag="JXV47_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAX1487033.1"
                     /translation="MKNPMFSIIVPIYCVEKYLKDCLDSIRNQTFKNFEAILVDDGSP
                     DECPEICDYYSQIDGRLKVIHKKNGGIIDARKTGVTSAMGEYIVFLDGDDWLANTYLE
                     KYAEVITKYNPDIICSGYFASRSNKIRKRELSCSFGYYDKDKIINLIYPKLIEDEHGE
                     YFRPQLWAKAFRTTLYKEQQQVSGQVSVGEDHACTKPCIYHANSIYMMEKCLYYYRIN
                     ENSITKKPQPYYWEGPKAIGEHFEKQIDMNKYDFQDQVYRNVTHNLFNVAVSQFNKQD
                     KYLNIKKDIIQNLSDEYYTRAICKCKYKDNWKGISAKFALKNKWVFLIYIYNKLIKR"
     gene            42989..44035
                     /locus_tag="JXV47_000975"
     CDS             42989..44035
                     /locus_tag="JXV47_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAX1487034.1"
                     /translation="MSVKISVIVPCYNVEKYIDECINSLINQTLKDIEIILLNDGSTD
                     NTLAILKKYEKLDSRIKVYEHKNMGLGPTRNRGIKIANGEFLAFVDSDDFVSNTMFES
                     LYNCAIAENADIAIGEVGIFSDREIERVKIRKSLTNLKTIELATYNKKEFFKQFYFNR
                     LYSHNAWDKIYRRSLVLEFNLSFGDNKIIFAEDNWFQLQVFMTNTRICFVDKLCYYYR
                     QQNNSIMHKPKSNLVFRHGNMIADYEKLIRQNGNNIIDKKACMLVAFDVLIMEIFNQK
                     NVGGTCEDYKNALVSLKHHKILRENISNIVRMKAYELEPNMRKKLALVTISIMFNFKM
                     YKTAYNMLWRIYNR"
     gene            44049..45128
                     /locus_tag="JXV47_000976"
     CDS             44049..45128
                     /locus_tag="JXV47_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAX1487035.1"
                     /translation="MRKLTFVIGIMGKGGAERVIANLANNFIQDNWEIDIITIYGNRQ
                     DYELNRKIQVHPIICKSSFRAFRPLERFKELRKKIREIQPDLVISFLADVNIHVIISL
                     LGVKQKLIVSERNDPQRNPEEPWIRKIRDFLYKNVDGIVFQTPDAKKYFSKINDKKVK
                     TIIIPNPIKENLPYYNKTTSSKKFITACRLDKQKNLPLMIDAIGKLIHEGYECELDIY
                     GEGGLKTELESYINHNGLTEFVHLKEFTNKIHEKMQNAAGFVISSDYEGISNSMLEAL
                     AIGVPVIATDCPVGGARMYLGDRNEIGHLVECNNLDKLTDAMRRVLLDRESVVRKAQK
                     GIKLRKELTSKNISNIWYEYLNQFF"
     gene            45171..46571
                     /locus_tag="JXV47_000977"
     CDS             45171..46571
                     /locus_tag="JXV47_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy"
                     /protein_id="HAX1487036.1"
                     /translation="MFSLTLVAFTIFCAFSLNQNYWLNWLGILIYLYAICTWHWRKGD
                     SIFSLYTIFFTLFLLFSYGQCIMWAFGIGTDRGIGTTVVAYGTGIIPSESDMIMVKWY
                     SCISMFVFHIGALLFTRKTTLRKVSWYESGDADADRKFLFKIGCIISIIVVPIVFVSK
                     LLEVRIALVHGYNALYYGDYATQSGYLQIILYLFFPALICLLIGSNFSKVITRFVFII
                     FALYSLLGIMSGDRGSWLYSSIILIWAYTQYKGTFNYKKLIKWLILAVIGIYILNVIT
                     KARDGGGLSKLTLKDFTSVFDSDDSPLVDSFFEMGGTMSIITFFLISGNGIYPFANTY
                     LTSLLGSISTRMLSMFGIKFVLLADWFSQDYLGITWGTGFSMIAEAYVNGGYIGGIVY
                     IFIIGIVIGKILSNSIDNQDIENHPMKMFLAITTANIIMGFPRAASYLIVKNFVYGVL
                     IILLINFFLQQFNKRL"
     gene            46617..48122
                     /locus_tag="JXV47_000978"
     CDS             46617..48122
                     /locus_tag="JXV47_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar isomerase"
                     /protein_id="HAX1487037.1"
                     /translation="MERTARLKKNTIWALVFQITSIVCGMILLRLILTKYGSEVNGMI
                     SSINQFLQIISFLQLGVGAVMQSTLYKPLAEKDNLMISQILASGGKFYRQIAYILLVY
                     VGLLLAVYYVLVPNEFGRSYTMAMIATLSINSFAQYYFGIVNTLLLSADQKIYITYIA
                     QTIAFISNTVACALLISLNTEILMVKLITAIIYLACPIYYRWYVDRNYNIKRNVSYDK
                     EPIPQKWNGVAQHVASVVLDSTDVVVLSIFSNLIYVSIYNVYNLVIYGVKQLFMAMTN
                     GVQALLGELWVRKEIEVLYKTFAWFEWIVHTLTVFIFGCTGILIVPFIQVYTRGVTDA
                     NYNQLSFAALLVTANALHCLRTPYHVMIKAAGKYKETQNSFIIASLLNLGLSLILVKP
                     LGLVGVALGSLISITYHTLWSANYNSKYLLKWPMKKFYKQLFVNILTVVLSFGATSQL
                     KMMSITYLDWIVLAIKCAVIVFICIILVNVLFYRRYVVKIISKIIVKIKKI"
     gene            48419..49510
                     /locus_tag="JXV47_000979"
     CDS             48419..49510
                     /locus_tag="JXV47_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAX1487038.1"
                     /translation="MLELNTSLSNRTILITGAAGFIGSNLVLELLRTQSSIKIIGIDN
                     MNDYYDVSIKNYRLSEIETEAKNHPGSTWNFIKGSIADKATIDFIFDNYKPSIVVNLA
                     AQAGVRYSITNPDMYIESNIIGFYNILEACRHSYDNGESGVEHLVYASSSSVYGTNKK
                     IPYSTEDKVDNQVSLYAATKKSNESMAHAYSKLYNIPSTGLRFFTVYGPAGRPDMAYF
                     GFTDKLRAGDNIQIFNYGNCKRDFTYIDDIVEGVKRVMQCAPEKIDGEDGLPIPPYHI
                     YNIGNNTPENLLDFVDILQQELIAAGVLPEDYDFESHTELVPMQPGDVPVTYADTSAL
                     ERDFEFKPSTSLRDGLRKFAQWYKSFYEV"
     gene            complement(49578..51056)
                     /locus_tag="JXV47_000980"
     CDS             complement(49578..51056)
                     /locus_tag="JXV47_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HAX1487039.1"
                     /translation="MKKLSQKRLAQIIIDSRKSLKMTQQQLAVATGINRALISRLESL
                     DFIPSIQQLESLAEVLNFEPTDLFINESNKSNRTKHQSKNIAVAGTGYVGLSIATLLA
                     QHNQVTAVDILPEKVKQINNKKSPIQDDYIEKYLAEKNLNLIATTDGAAAYREADFVV
                     IAAPTNYDSKQNYFDTSAVESVIKLVLEVNPKAIMVIKSTVPVGYTESIRKKYNTKNI
                     LFSPEFLRESKALYDNLYPSRIIVGTDQTDKTLREASHTFADLLQEGAIKKDIETLFM
                     GFTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLNTQEIIHGVCLDPRIGTHYNNPS
                     FGYGGYCLPKDTKQLLTNYNDVPQNMISAIVDSNRTRKDFIADRVLELAGTYEANSSW
                     NAEKEKEVVIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGATIVIYEPTLENNTTFFG
                     SKVINNLDDFKNISHSIIANRYDSNLDDVKEKVYTRDLFQRD"
BASE COUNT        17375 a         8378 c        10465 g        14881 t
ORIGIN      
        1 ttgattttgt cgctttcgtt tatgagctat ttttcttaca ccttttactt gactaatcgt
       61 aggaaaggga actgtgacaa aagtcttgtc gcagttcctt tttccgaata aacggtgctc
      121 aaaagcttgc atctgcggta ataagtccaa ccaagttaaa aacataaaaa gctgttttta
      181 cttggctgtt cttattactt gatgcaaggc agctttttca caacctctga tacacggtgt
      241 tccagaagta acttcttcgg aaataagccg aaatttcaca aaaatttgaa aagcaatttt
      301 cttaaattcc ttcttatttc ttgaagctgc ccacttctga cacaacctcc tttgtgtaaa
      361 agaatcagtt tctactcgat ttcttctatc gtttcctgca aacgctgttc atattttttg
      421 tttcctttat ataaatcacc aatcgtccat gccaacagga gaaggacaag aacaatgatt
      481 acataagcga tttgatcagc caatgctagt tgagctgagg tggcttgctc gccgaagaaa
      541 ctttcgattt gacctggtaa tcctcgtaaa ttcaagtaag tcagactaat cacagagaac
      601 cagccaagta gttttacaac aaatgaattt ttgaatcggc tccccatctc cgcttggcta
      661 ttggtcatca tcagtaaagg aatcatcgag aatggcaatg caaaagccag aaaaacttgg
      721 gattcattca tcaagttatt caaagcggta tgttcttcga tcgttccttt tgtacttgta
      781 aacaaaacac aaatcaatac aggaatcaca gaaagcaatc gtgtgactag tcttcttagc
      841 caaattggga tacgcatatg gatgaagcct tccatgatga cttgaccggt caacgtacca
      901 gtaatagtag agttctggcc agaagcaaga agtgctacag caaataaagt agacaagata
      961 ccagattttg ctacagcaat caagatacca ttgctcatag ctgatggatc agataaagct
     1021 tcatacagac caaaaaagga aggatcttgg acagaaccgg ttttgaatac agccacaccc
     1081 atgatcaata gcagtgcatt gactagaaaa gccattgaca actggatatt agaatcccaa
     1141 gtagaaaagc gtaccgcttg tgctacatct tcttcgtctt ggtgatcgat cttccgagtt
     1201 tgagaaactg ctgaatgaag atataagtta tgcggcatga ctgttgcacc aataatccct
     1261 aaagctccag tcagcggagt ttcgccgccg atgaccggtg agtctgagaa tgtgtgactg
     1321 ttagggataa atccggcaaa caaactgtgc caatcagggt tagacaagcc aacttgatag
     1381 acgaaaacga ataaaatgac gaaaatcaag cagacaacca aagcttcgat tttacgaaac
     1441 ccgacttttg tcagcaataa aaggacgaaa acatctaaca cagtgataaa tacggcaatt
     1501 accaatggaa tatcaaaaag caggtagagg gcgattgctg caccaatgac ttctgcgatg
     1561 tctgttgcca taatggctaa ttcagtcaag atccataaaa tgacacccaa tgtcttactt
     1621 gtccgtgctc ggattgcttg ggccaaatcc atttgggtca cgattcctaa ttttgctgcc
     1681 atatattgta aaagcatagc aatcagacta gacatcaaaa taactgacat caataaatat
     1741 tggaaatttt gtccaccagt gatcgaagtg gaccagttac ctggatccat ataaccaact
     1801 gctactaatg cacctggtcc agagtaagca agaagtgttt taaaaaaact ttttcccttg
     1861 ggtacatcca ctgttccatt tacttcagct aaagataaac catttgtatg ttcaataagt
     1921 cgatgcttat gaaattgttt gttggattga ttattcaaga aaaaaccacc tttcctattt
     1981 atctacgatt acattctaca cctcagaaag aaaaaattaa agaaaaagat ttggtatgcc
     2041 taattttttt tcgtggcgtg tcttgctggt taatgaaaga aattttgttc ttctctaaaa
     2101 aaaccactat tttttgcatg aaactaaaga atacgccttt cttttttcaa taaactttag
     2161 taaaataaat cattgagagc aattcggaaa tagaaaggag agatttatat ggtatcaaca
     2221 ggtattgtcg tacttattgc tattattgct ttgctaatcg gcgcagtagg tggctttttc
     2281 ctagcgcgta aatatatgaa agactattta gaaaaaaatc ctcccgttaa tgaggacatg
     2341 ttgcgatcaa tgatgatgtc aatggggcaa aaaccatctg agaagaaaat tcgccagatg
     2401 atgcagcaaa tgaagaacca agggaaaaaa taggttctga cccaaagact ttttgcgggc
     2461 tgattttttc agtccgtttt ttatttcgta atttgttaga ctattcagac tattcagcaa
     2521 aaaagacaag cacagacaat cctatgctct tgataaagac aaaggaggag taaaatgtcg
     2581 atttttagaa aattaggttg gttttttcga caggaaaaga aacattattt aattgggatt
     2641 ttctccctat tcgcagtggc cttggtacag ttagctcctc caaaagtgat tgggatcatc
     2701 attgatgaga tcgccgataa aaatttatca ataaagatca tttcctggtg gatcttatta
     2761 ttgatccttg cagctctctt acaatatctt tttcgttata tctggcggac gaatatttgg
     2821 ggaagtgcag ctcggttgga gaaagaactt cggcagcagc tattcaaaca ttttacagaa
     2881 atggacaatc tcttttacca aaaatatcgg actggagatt tgatggctca tgcaacgaat
     2941 gatttgaatg caatccaaaa tgtagcagga gctggtatct tgacctttgc agattcagtg
     3001 atcacgggcg gaacaacgat cattgcgatg attttgttta ttgattggcg cttaacactg
     3061 attgcgctga ttcctctgcc tttactagcc gttacttcac gagtgctggg gtcaaaactc
     3121 cacgatgctt ttcgtgattc gcaagaagct ttttctagta tcaatgataa gacacaagaa
     3181 agtattactg ggatcaaagt cattaaaaca tttggacaag aaaaagaaga tctcgcggat
     3241 tttgaagaaa agattgaaga tgcaattatt aaaaacaaac gagtcaattt tttagactcc
     3301 ttatttgatc cattcattac cttgattatc ggtctgtctt atgttgcaac aattatttta
     3361 ggtggaaagt atgtcttgga aggcacgatc tcaatcgggc agatggtctc atttattagc
     3421 tatatcggta tgcttgtttg gccgatgttt gcgattggtc gattgttcaa cgtattggaa
     3481 agaggaaatg cttcttatga tcgcgtcaat gaacttttgc atgaaaagac gcatatcgtg
     3541 gaacaactgg gtgcagtgca gactccggca aaaggcgagc tgaatgtagc tatttcctct
     3601 tttaactatc cgaaagaaga atcaccagca ttagaacaaa tcaaatttgc gatccaagaa
     3661 ggagaaacat taggtattgt tgggaaaact ggtgcgggaa aaacgacaat catcaaatta
     3721 ctgatgcgtg aatacgatga ttatcaagga aaaattcaat ttggcggatg ttcgatcaaa
     3781 gaatattcat tgaatgcttt attaggatca atcggctatg tgcctcaaga tcacttcttg
     3841 ttttcgatga ccattcgaga taatatccgt ttttctaatc caaaactttc agaagaagaa
     3901 gtagagcatg cggcttcttt agcatttatc aacaatgaaa tcaaggaatt accaaaaggt
     3961 tatgatacct tagttggaga acgtggagtc tctttatctg gcggacagaa acaaaggatt
     4021 tcgattgctc gagcattgat caaaaatcct gaattgctga tcttagatga tgcactttct
     4081 gcagtagatg ccaaaacaga agaagctatc ttgcataatt taaaagaaat aagaaaagag
     4141 aaaacaacca tcattgcagc tcaccgttta agcagcgtga tgcatgcaaa agaaatcatt
     4201 gttgtcgatc aagggaaaat cattgaacga ggaacccatc atgagctgct tgcattaggc
     4261 ggctggtatg aacgaatgtg ggagaaacag aaattagaag cgaagataga aggaggcgag
     4321 gcctgatgga tgaaaattat caatcggaat ggacaaaatc gattccactt aaagaacaga
     4381 agaagatcat caaacgactg atgaagttcg ccaaaccttt tagaagaacg ttcatcgttg
     4441 ctatcttatt tgcgtttgcc ctgtctgtga tcaatgtcct attgccaagg atcatccaaa
     4501 cttttatgga tgatcatctg gctaaacagt cggctacgac acaagttatt ttgttttttg
     4561 ctggtatgta cttgtttgga gtcatagtca aaagtatcat ttggtttttc caatggtatt
     4621 tgtattccat ggcttcattg aagacctatc agtatgttcg ggtaagatta tttgaaaagc
     4681 tgcatacact aggtatgcgt tattttgatc agacaccggc aggatcgact gtttctcgag
     4741 tgacaaatga cacagaaacg ctatttgaat tttggtatgt ctttttgatg gtattgactg
     4801 ggatctttgc agtcgtttct tccttcattg ccatgtttca aatcaatgga gaaattgcct
     4861 tgtggacttt ggtgttcttg ccgattttag gaatcgtcat ctggtattac cagaaattca
     4921 gttctcgtat ttaccggaat atgcgggaaa aattaagtca gctgaacacg aaattgaatg
     4981 aatcgatttc cggcatgcgt attatccagc agtttcgcca agaagctcgt ttagctaaag
     5041 aatttgaaca agtgaacaac gagtatttag acacgcgcta tgcgatgatc aaaacaaatt
     5101 cgattctgtt aagtccgatc atcaattttc tatatgcatt ggcgattgcg ttggcgttga
     5161 ctttgtttgg gatcgatgcg ctgcattctc ccgtagaagt tggactgatc tatgcattta
     5221 cgacctatgt ccagggattt tttaatccaa tgtctcaaat gatggacttt ttgagcacct
     5281 ttacagatgg aatggttgcc ggtagtcgta ttttgaaaat catggataca gaagaatatg
     5341 caccgcaaca aaatcctgga gcagatcaag cgattacttc aggtaagatc gagtttcgca
     5401 atgtaagctt ttcttatgat ggagagcaca atgtattgaa caatatctct tttgtcgcta
     5461 atccgggaga gaccgttgca ttagtggggc acaccggaag cggaaaaagc tcgatcatca
     5521 acgtattgat gcggttttac gaattttatg aaggccagat cttgattgat gatcatgaca
     5581 ttcgagaata tccaatggaa gagttacgta agaaaatggg attggtcttg caagatgcct
     5641 tcttgtttta tggagatatc gcaggaaata tccggatgat gaatccaact atcacagacg
     5701 aacagattcg ccatgcagct gagtttgttc aagcaaacaa gttcatcgat gaattaccaa
     5761 aaggatatca ctcaaaagtg atcgaacacg gtgccagcta ttctagcgga caacgacagc
     5821 tgatcacttt tgcgcgaaca atcgtgacag atcctaaaat actagtattg gatgaagcga
     5881 cagcaaatat cgatactgaa acagaaggat tgatccaaga aggattgaca aaaatgcgac
     5941 aaggacggac aacgattgcg attgcccatc ggctgtccac gattcgggat gcagaattga
     6001 ttttagtttt agacaaaggt catatagtag aacgtgggaa tcatgaaaca cttctagcgc
     6061 aaaatggttt gtatgcagat atgtacaaac tgcaaagcag tggtgtgtaa aaagtggttg
     6121 tgacagggct ccgttcagct ttaggtgata agaaaaaaat tgtaaaaaag gctttccaga
     6181 tttttgcata aatttggctt atcaccgata agctggtact ggaacaccgt atattagaag
     6241 ttgggacagt agcatagtag cattttgacc taagcgctag agtgaaaata aaacagagct
     6301 tcccagattc ttcatctgtg agcgttagtg tcgtaattac cagatttaaa aaaaatcacg
     6361 acagctagtc agaagtgccc aatagccgct aagaaagcgt tgacaaaagt gcttgctttc
     6421 gataatataa agaaaacgat acaacttgga tagtgattgc ctgatgcaag ctaaacctga
     6481 tgagtctccc atggttccat ggacggcttt ttgggttttt ctttttgttt tggatacagc
     6541 cctatatatc atggaaagga gtaaaacatg ctgattgaga aagtactgaa taacaacgtc
     6601 gtaataacca gggatgaaag aaatcaggaa atgatcgtga tgggaaaagg tttggcattc
     6661 aaaaagaaag tgggtgaccc gatttttgac tcatgcatcg acaaaaaatt tcagttgaca
     6721 aatgacggac tttcacaaca gttccaagaa ttggcacaag cgattcctct tgagtactta
     6781 gaaatttctt gtgaaatcat tgaatataca aaagaggctc tacaagtcca gttgaatgat
     6841 tcggtgtata ttgcattgac ggatcatttg tatacggcta tcgaacgtca caaaatggga
     6901 atatttgtac caaatgtatt gctgtatgat atcaaacaac tatttcctaa agagtatgcc
     6961 atcgggaaaa aaacagtgaa gaaaatctcg gataaatacc acatcaagtt atcagaagat
     7021 gaagccggat ttatcgcatt gcatttagtc aatgcacaag gcattcaaag ccaacaagac
     7081 aatacctacc tgtttactac aacaatacag gatattctaa atatcgtccg ctattactat
     7141 aagattacat ttgatgaaga ttcagtccat ttttttcgat tcgtcacaca cctacgtttt
     7201 tttctgacac gcgtcctaga tggagaaaaa tcagaagtgg gagaagtttc tgaggaattg
     7261 taccaggtta ttcaaaaaaa atataaggat acgtttggtt gcgttgagaa aatagcagac
     7321 tttttagccg agatattcaa ctaccagatg tccacggacg aaaaaatgta tttaacgatc
     7381 catattgcgc gtttagtgca tgagaatcgt tgtaaataaa taaaaaaagg aggataaatt
     7441 aacaagaacg catgaaataa gggtagtgac attcagttgg ctaaaccttc cactaataaa
     7501 ttggagggaa tagaaatggg aaaatatcaa gaattagcga gcaaaattgt agaaaatgtc
     7561 ggcgggaagg aaaatatcaa tggtttgaca cattgtatca caaggcttcg tttcaaatta
     7621 aaaaacgaag aaaaagcaaa tgatgagatc ttgaaaaata tggacggtgt tgtgacggta
     7681 atgcgagcgg gaggacagta ccaagttgtc atcgggaatc atgtgccagt cgtgtttgaa
     7741 gaggttataa aagcaggaaa ccttactttt gatgaggctg tttcaacaga aaaaatgaga
     7801 ccgtttgata tgcttattga tggaatatcg ggctgtttcc agccattcct tgctattcta
     7861 gctgctggtg ggatgattcg tggactgaca gcattacttg tcttcttagg cgcatttgac
     7921 cgcggttctg gcacatttgt tatgtttgat aatatcggtg attctgtatt ccaatttatg
     7981 cctgttatta tcggtttaac agctgcccgt aaatttaaag taaatgaatt cgtagggatg
     8041 ttgcttgggg cagcattaat gaatcctagc ttgtcgctgg aagctttgag tggtgcagca
     8101 gaagcaccac tgactaccat attttctggc actatttttg aagcacctat ttatcaaaca
     8161 gtattcggca ttccctggat tgcgcgtaac tacgcttctt ctgtcattcc cattatcttt
     8221 attgtgttgt tagctagcca aattcagaaa ccaattaaaa agttagtacc tgagatgatc
     8281 gcgaatttct tcgttccatt cttcaccgtt cttattacaa tgcccttagg ttttttactc
     8341 gttggaccag cattcacatt cgcaactgat attttaatgg ctggatttga aacactttta
     8401 gcactttcgc cagttattta tggagcaatc gtaggcttct tctggcaaat tctagtgatg
     8461 tttggtctcc attgggcaat cgtaccaatg ggattgatgc aattttctgt gaatggttgg
     8521 caaaatatca tgacacctgt tgcagtagtg tcttttggac aaactgcagc acttactgca
     8581 ctctacttta agcttagaaa cccaaaagac aaagcaatcg caataccagc cattgtttct
     8641 ggtattgtgg ggattacaga gccagctatt tatgggttta cattgccacg taaaaaaata
     8701 tttattttta cctgtgtcgg tggtgcgtta gggggcgcgt atagtggatt aatgaattta
     8761 acttcttgga atccaggtgg attaggcatc tttacaattc ccaactatat tagaccagat
     8821 ggtgatttaa cggatgtgat taatgtattg attggaatcg ccattgcgat ggtggtatcc
     8881 tttgcgctga cttttttctt ttggaaggag gaagcaggtg aaacagatga tagacagaaa
     8941 agatcaggta aagaaattgt aaaaacaccg atacaaggac aaatcgctcc actgaatgca
     9001 gcaaaggatg cagcttttgc acaaggaaca ctaggtcgag gaatcttgat ctaccctgaa
     9061 aaaggagaag tacgtgcccc ttttgacgga acagtcatga ccctgttccc gacgaaacat
     9121 gcaatcggaa tggtttctga agcaggtctg gaattgctga ttcatgtcgg attggatact
     9181 gttcagttgg aagggaaata ttttgaaagc ttggtgcagc aaggagaaag agtgaaacaa
     9241 ggcgatctgt tgctccgctt cgacaaaaag aaaatcgaag aggaaggata cagtttagaa
     9301 acacctgtga tcgtcaccaa ttacacggat tatttggata ttttggaaaa tcaaggggag
     9361 acggtcgggc cagacgatgc acttatcacc gcactgacct gaacggttag gtgaaagaat
     9421 ggactaggct taattattct ttttagtcca cttctttatt ttcaaaattg aaaggctctt
     9481 tcatgatggc tgagctgata gggcgtttat caaatttttg tcctacagaa attagatgga
     9541 ctaaattctg ttgataattt tctgcaaaaa cacaactata taacacgtct agaagataac
     9601 aaatcgatgt attgatcgta aaattaccaa ttttcgaata cagtcgttcg cgtgtcgtaa
     9661 gtcgcaaagc ggctgtactc attgaagata gcgttgaatc accgatactg gtcaaagcta
     9721 aaattggaac atgattttgt ttcaatattt ctgcggtacg aaggatcaca ttgttttcac
     9781 ccgtataaga aatcagaatc ccgcacatat cactcgtgca attgtacgct tcatagaacg
     9841 attcaccaaa agtggtgaca atcgtgacat ccattttgat gcgcttcatt ttcagcatga
     9901 aatcttgaga aatcaaagta ttcgagttac tggcgaaaat cacgattttt tttgcttgaa
     9961 gcattagttg tttggctttt tgcagttggt catgatgaat gagagaaagt gtatcttgaa
    10021 tcgtcatctg ttctaaagaa gccattttat ttgcgatcgt cataataccg tctgtggtgg
    10081 aaaaaggaag attcgcatct acgtcttgaa aattcccttc aagataggct gtttcagcta
    10141 aaaaagcatt acgaaaactg acccagccat caaaacccat tttttttgct acacggatga
    10201 gtgtggacgg gtggacataa catcgctcag caatctcttg gatggtcatt tcgccaagtg
    10261 ctggagaatc gcttaagaga aactgaatca cttcattttc tgaaggagaa aaggagattt
    10321 ctttgatttt ttcacgtaat aacatgtaga taccttcttc ttgttttttt acgtaaatta
    10381 taactttttt gaaaatgatt tgtaaacgga tttatgttat atagcttaat aaagacattt
    10441 tttgacaaga tatttacaaa aatccagtag aaaacactaa cttttgtaaa tgttactgga
    10501 aagaaacgaa tttctattgt ttgttttgtt tacaaaaaag ataataaaag tgtaaaaagt
    10561 aaaggagtga gaacatggca aaaggaatca aaatcgctac gattggtgga ggcagcagtt
    10621 acacccccga gttgatggaa ggatttatca aaagatatga ggaattaccg atacgagaaa
    10681 tctggctcgt agatgtagaa gaaggaaaag aaaagcttga gatcgtcagt cagatgtctc
    10741 agcgtatgtg ggatgcttct ccgtatgaag tcaaaatcta tgcaactctg gatcgggaag
    10801 aagcattgaa agatgcggat tttgttacga ctcagtttcg tgtcggtcaa ttagatgcac
    10861 gaatcaaaga cgagcggatc cctagttatt atgggatgat tgggcaagaa acaaatggtg
    10921 ctggcgggat attcaaagct tttcgtaccg ttccagtggt tttggcaatc gttgaagaca
    10981 tgaagcgttt atgtccaaat gcttggctga tcaatttcgc gaacccaagc gggatggtga
    11041 cagaagcagt tatcagatat ggcaaatggg ataaagtgat aggattatgc aatgtgccag
    11101 taatggcgat gatgacagaa ccaacaatgc ttggcaagaa aaaagaagag ctgatctaca
    11161 agtttgccgg tctaaatcac ttccattggc acaaagtagc agataataaa ggaaatgacc
    11221 gcacggcaga attgattgat cgtttatacg atgaagacaa tggattgccg aaaaatatct
    11281 ttgatatccc gtttttcaaa gaacaattaa aacaaatgaa catgatccct tgtggctacc
    11341 accgctatta ctaccgtgaa gaagaaatgc tggaacatgc tttagaagaa tatcaaacga
    11401 ttggtacaag agcgcagcaa gtgaaagaaa cagaagcaga gctgtttgaa ttatacaaag
    11461 atccagaatt ggatcataaa cctgaacaat tgcaaaaacg aggtggtgct tattattcag
    11521 atgctgcctg tgaaacgatt gcttcgatct atggaaataa agaaacacag atcgtggtat
    11581 ctacaaagaa tgatggagct gttcctgatc tgccggcaga ttgtgtagta gaagtcactg
    11641 cctatgttgg cgcacaaggc gcacgaaatg tagcgtttgg ttcccttcct gctgctgaaa
    11701 gaggctggtt gcaagtaatg aagaatatgg aattgctgac gatcgaagca gctgtgactg
    11761 gtgattatgg aacagcttta caagcgttta cgatcaatcc gcttatacga tcaggaaaga
    11821 cagcaaaacg gatcatgaat gagttgttta ttgcacatca gcagtattta ccgcaattca
    11881 aggaaacaat cagccggtta aaagcagaag gaatcgaagt ccaagatgaa ctggcaagag
    11941 aattatcaag caatacacat gtaatggagg aagtatgatg ggattcagaa aagatttttt
    12001 atggggcgga gctacagcag ccaatcaatg cgagggcggt tatgatgaag gcggacgtgg
    12061 gttagcgaac gtagatgttg tgccaatcgg agaagaccgt tttcctgtca ttactggaaa
    12121 aaagaaaatg tttgaatttg atgaaaatca tttttatcca gcaaaaattg cgatcgatat
    12181 gtatcatcat tataaggaag atattgcttt atttgcagaa atggggttca agacttatcg
    12241 gatgtccatt gcttggagtc gtatttttcc aatgggcgat gaaaaagagc caaatgaatc
    12301 tggtttgaaa ttttatgagg atgtctttaa agaatgtcaa aagtacggga tcgagccgct
    12361 tgtgacgatt acacattttg attgtccgat gcatttgatc aaagaatatg gtgcgtggcg
    12421 ttccagagaa ctcgttggtt tttatgaaaa tctgtgccga gtcatcttca atcgctataa
    12481 aggacttgtc aaatattggt tgacattcaa tgagatcaat atgatccttc atgcaccatt
    12541 catgggcgca gggctgtatt ttgaagaagg agaaaatgaa gaacaaatca aatatcaagc
    12601 ggcacatcat gagttggttg caagtgccat cgcaacgaag attgctcatg aagtagatcc
    12661 ggagaacaaa gtaggctgta tgctggcagc aggagcatat tatccataca cttgcaatcc
    12721 tgaagatgtt tgggcttcta gaaaatcaga tcgagaaaat tatttcttca ttgatgtcca
    12781 gtcacgagga gaatatcctg cttatgcatt gaaagaaatg gaacgaaatg gcattcagat
    12841 caaaatggaa cctggggatg ccgcattgct gaaagaacat actgttgatt ttatctcctt
    12901 ttcttattat tcttctcgag tttcgactac tgacaacgaa ctcttggaac agactgcagg
    12961 aaatatcttt gcttctgtca aaaatccata tctggaagca agtgaatggg gttggcaaat
    13021 tgatccatta ggcttgagaa taacgatgaa tgatatttat gatcgttatc aaaaaccact
    13081 atttattgta gaaaacggct taggtgcagt cgatacgccc gatgagaatg gttatgtgga
    13141 agatgactat cgaatcgact atctggcagc acatatccag gcaatgaaag atgcagtaga
    13201 attagatgga gtcgatctat taggctatac gacttgggga tgtattgatt tagtatcagc
    13261 tggtacaggt gagatgaaga aaaggtacgg attcatttat gtcgatcgtg acaacgaagg
    13321 aaatggcaca ttagcccgtt cgaagaagaa atcattcaac tggtataaaa aagtaattga
    13381 ttcaaatgga gaaaatcttt cgaatgattg atcaatgatt tataaaagtc tattgttttt
    13441 cagcggattt ttcgagtata ataaagctat tcgagaaacg caagcagaac aatagacttt
    13501 ttttcgcatt ggctgtaaag tatgcttact tgattaagta aaggagaatc tacatatgta
    13561 tgatgtaatc gttattggcg caggtcctgc tgggatgact gctgctttat atgcttcacg
    13621 ttcaaactta tccgtattga tgatcgaaca aggcgcccct ggcggccaaa tgaacaatac
    13681 ggcagaaatc gaaaactatc ctggtttcga ttcaataatg ggtcctgatc tagcttataa
    13741 gatgtatgaa ggtgtttcaa gatttgggac agaaaatgct tatggaatcg tgcaagatat
    13801 caaggatcac ggcagccaca aagaagttat ttgtgaagat aaaacttacg aaggaaaaac
    13861 agtcattatc gcaacaggct gtatccaccg taaattaggc gtacctggcg aggaagaatt
    13921 tgctggacgt ggcgtttctt actgtgcagt ttgtgatggt gcgtttttcc gtaacaaacg
    13981 tctagtagtg atcggaggag gagactcagc agtagaagaa gccatctatt tgacacaatt
    14041 tgcttctgaa gtagtcatcg tccaccgtag agatgaatta cgtgcacaaa agatcatcca
    14101 agaccgtgca tttgcgaatg aaaaaatttc ctttatgtgg gatacagtcg ttgacgaaat
    14161 cgttgggaat gaaatggtag tgacaggtgt gaaagcacgt aatgtcaaaa ccggcaatga
    14221 gtttgatttg gcagcagacg gagtattcat ctatgttgga ctggatccat taactgcacc
    14281 atttagagaa gcagggttga cgaacgaagc tggctggatt ccaacagaca acgaaatgaa
    14341 gacgaatata ccaggcgttt ttgccatcgg agatgttcgt gaaaaagatt tgcgacaaat
    14401 cactactgct gttggtgatg gtgggatcgc tggacaacaa gtgtataaat acttggaatc
    14461 tttagaagaa acaactgcat aagtttaaaa agagtggaag aacggtttaa ttgttctttt
    14521 actctttttt ttcgcgtgaa atctactgaa tccgatttat gcgaatactt gcaaccgtgc
    14581 ttgataaaag aatcctttct tgatttaagc gttttttggt cctcatactt tcatatctaa
    14641 taagtgaatg ctatacttat taagaaccat atttcagaaa gaggtgttat tttcatgtct
    14701 tgggaacaag tgtatgaaca atgggtacat gaagaaaatt tagaagaaaa cttaaaaaaa
    14761 caattaaatg atctgggtga agatcctgaa aaacttgaag atgcttttta tgcaccgttg
    14821 gaattcggta ctgcaggcat gcggggaatc ttagggcctg ggatcaatcg aatgaacatc
    14881 tatacggtaa gacaagcaac agaaggactt gcacgtttca tggatacaca aggcgaagaa
    14941 acaaaacgcc gaggtgtcgc tatcgcttat gactcacgcc atcaatcacc agaatttgcc
    15001 atggaagcag ccaaaacatt agcacatcac aatatcccat cttatgtatt cgaaagtcta
    15061 cgtccaacac cagagctttc ttttgcagtc cgtcatttga agacgtttgc gggaatcatg
    15121 gtaaccgcat cccacaatcc agcagcttac aacggatata aagtctacgg agaagatggg
    15181 ggacaaatgc ctcctgcaga cgcagatgca ttgacgaaat atgtccgtga agtcagcaat
    15241 ccgttaaaag ttgaagtatt atctgacgaa gaagctgaac atagcggatt gatcacgatc
    15301 atcggagaag aagtggatgc cgcttatcta gaagaaatca aagcagtaac gattgatcat
    15361 gaattggtgg aaacaatggg gaaagatttg aaacttgtgt acacaccact tcacggaaca
    15421 ggaaaaatgt tgggcgaacg tgcgttgaaa caagctggat tcgaacaatt cgtactagtt
    15481 ccagaacaag ctgtcgcaga cccagatttc actacagtca aatcaccaaa tccagaagaa
    15541 cactctgctt ttgagtatgc gatacgactt ggcgagaaag aaggcgctga tttgctgatt
    15601 gcaacagatc ctgatgcaga ccgtttaggt gcagccgttc gtttgccaaa tggctcctat
    15661 gaagtattga ccggaaacca aatcggagca ctgtttgctc aatatatttt ggaagcacac
    15721 caatcgcgag gcactttacc tgaaaacgca gcggtattga aatcgatcgt ttctagcgaa
    15781 ttacctacag caattgcgga acactatggg gctaccatgt tcaatgtatt gacaggattc
    15841 aaattcattg ctgaaaaaat tcaacaattt gaagaagatc attcccatac ttttatgttc
    15901 ggattcgaag aaagttacgg ttatttagtt aaacctttcg ttcgcgacaa agacgcgatc
    15961 caagcattgc tcttattagc agaagtagca gcttactata aaaaacaagg caaaacgttg
    16021 tatgatggct tgcaaacgat ttttgaaacc tatggctact acgcagaaaa aacgatttct
    16081 gtgacaatga gcggacaaga aggttctgcg aaaatctctg ctttgatgga aaaattccgt
    16141 gaagaagcac caacagaatt tgccggagca aaagtcatcc aaacagaaga cttcaaagag
    16201 ttgacgagaa cagaccgtga aggaaacgta gaaaaactaa cgacaccgcc atctgacgta
    16261 ttgaagtata cgctggaaga aaatggctgg atcgctatcc gtccttcagg aactgagccg
    16321 aaaatcaaat tttatatcgg tgtaaaagga aactcttcag aagacgcagc tgaaaaagta
    16381 gccgcttatg aaacgattat ccaaaagatg acagaagaat aaaaaaactt gagactgatg
    16441 gaaaaagtgg taaactttag aagtcagtct tttttcaagt tggaggtgaa tggattgcca
    16501 gacacgcaaa aaacaaaagt agagaaagtc agccaactat tcaaaatgtt gagtgacccc
    16561 actcgtctca aaattctgct gtatctgaaa gacggggaac aaaatgtgac agcaatcatc
    16621 caagcagtgg aaatggaaca atctgctgta tcgcatcaac tgcgtttatt aagagaaaac
    16681 catgtcgtca agtcccatcg tgagggaaaa gcgattttgt atagtcttga tgattctcac
    16741 gtactggata ttttgaacca gacactcaaa catgtggaac atcaataacg ataggtgcaa
    16801 atagagacaa actggactgt gtcaacgaat cttcttcgct gacacagtcc agttttttta
    16861 aagaaaaatt gttagtctgt ttcttcggtg gtttcagttc cataataact atggtcttct
    16921 aggtctaaag cattcaaaat aagcgaagct gtttcttcaa tagataaaga agcgacattg
    16981 attactacgc agcccaattt ttcataaaga tcattcgcaa aatcgagttc agctcgtatt
    17041 ttttcgatat cggaataagc agtatcagga tttaatccgt aagagcgcat ccgttcttta
    17101 cggatattgt ttaaaatatc tgggttattc gtcagtccca cgattttttt aggatcgatc
    17161 tcccaaagct gtttgggaat atgtgcttgt gggatcaaag gtagattggc aacttttaaa
    17221 tttttgttag ctaaaaacaa gctcaaaggc gttttggaag ttcgggatac gcctagcaaa
    17281 acgacatctg cttctagaaa cccacgagga tctttcccgt catcgtattt tacagcaaat
    17341 tccattgctt tgatccgttt gaaatagttc tcattcaata aatgaagggc gccaggttgc
    17401 cgaatgggct tgataccagt taagcgctcg atttctgata tcggcggagt catcacatca
    17461 aaactaaata attgatgttc ttcacaaaaa gaacgcgtca tctcgatcaa ttcttgattg
    17521 atcaatgtgt gcaggacaag agctttttct tctagtgcat cttgcagtgc ctgcatcaat
    17581 gttttctcat ctgtcacaaa tgttctgcgg aataaattga actcaacgct aggatattgg
    17641 gccatagtgg cttgcgctag ttttgtcgca gtttctccag cagagtcgga gatgacaaaa
    17701 aaagtaacga tttctgtaga atcggaagac atggataaaa cctcacttgc atttttttta
    17761 tgtttattat accatactct agaatgtgta cttcgtaatc attttgattt ggaggaataa
    17821 gtcatgaaaa aacagacgtt gatcgaacaa tcactagaaa cattgaaaaa taacggtttt
    17881 aaatatacta aaaaaagaga agcattgtta acttatttag tgaagcgcaa tcgctacgta
    17941 tccgctaaag aagtttttga ctatatgaat caggaattca aaggagtaag ttacgatacg
    18001 atttatcgaa atctccatga ttttgcagaa atcgatttac tggaagaaac cgatttaaat
    18061 ggagagatga agtttcgttt tcattgctgt caaggggaaa tcggccatca ccatcacttt
    18121 atctgtacgg tgtgcggaac aacgaaagaa atccatatgt gtccaatgaa ttatttcgaa
    18181 gaacagctcg gtggatgtac gatcgaaggg catagattcg agattttcgg aagatgtgaa
    18241 aattgtcaat aaggatttaa ataaaataac atttgataat tttaaaaaaa agcaagattt
    18301 ccttgacggt caaaacagca ttagatataa tatttacagg acagtcttgt tttttgagat
    18361 atatttcaat aacaattacg gttacttttt aagctcggag ggagggaatt aacatgtcaa
    18421 aaacagtcgt tcgcaaaaac gaatcacttg acgatgctct tcgtcgcttc aaacgttccg
    18481 tgtcaaaagc gggtacttta caagaatctc gtaaacgtga attctacgaa aaaccaagtg
    18541 taagacgcaa gaaaaaatct gaagcagcta gaaaacgcaa aaaattctag ttctgtgatg
    18601 aattggagtt ggtagtgtgt cactactaag tagattaaac gatgacatga aaacagcgat
    18661 gaaagcgaaa gataaggaat ctttacaagt catccgaatg atcaagtcat ctatacaaaa
    18721 cgagcagatt aaagaaggtc acgacttgac agaagaagaa gaattaacgg tgttgtctcg
    18781 cgaaatgaaa cagcgacgtg attctttgca tgagtttgaa gaagcaggac gtgacgattt
    18841 agctgaaaaa gtaaaaagtg aaattgtgat agtcgaaaaa tacatgccgg aacaactttc
    18901 cgacgaagaa attcgacaac ttgttcaaga agcaatcacg caaactggtg cttcatcaat
    18961 gaaagaattt ggcaaagtca tgggtgcgat catgcctaaa gtcaaaggaa aagcagatgg
    19021 aaaccaagta aatgccattg tgaaagaact attacaatct taattttatc atttaaactg
    19081 cggacaatca ttgtccgcag tttttttgtg ctcgtaaaaa agagatctaa aaaatagcta
    19141 gacgaaagaa taggattctt tcatctagct gtttttttcc tgtttaatat ttcttatgtt
    19201 aaattgtgtt tgatctggtt attcttctgg tagttcattt gcttcttgtt tataccctga
    19261 taggcgatag gcgtaataga agagtaagct gccagcatac ccaagtaacg ttgggaccat
    19321 ccagccaagt cccaatgcag caaaaggaac gtgatgatga taaaattcga gcatgcttgc
    19381 tacaactctt tgttgactca ctaaagcagg cgaatttgcc agcatatcca atacggcggg
    19441 aacagcagca aacaacatcg ttacttgata gacaaatggt gtcttttgga aaaattttgc
    19501 tgttaaggaa agcaaaatca acgcaagcga caatggatac aaaagcatca atactggtaa
    19561 agaccattgg atgatattgt ccaaaccagc atttgcaacg acaaaagaga cgaaagtcgt
    19621 taaccgcagc catgtcatat aactgacttt agggaacagt ttatggaaat cttgtgcaaa
    19681 agaaacaacg agtcccatag cggtagtgaa gacacctaat gtgaccatca ctcctaagaa
    19741 gctagcgccg aagttaccta aataaaaatt agtgatctga gaaagtgcag ttccgccatt
    19801 ttctgataaa gacatcttat tcaaactcat cgcaccgaga agaacaagac caaaatagat
    19861 catgacttct agcgcaacgc tcaggctacc agcttttgct gttaattctg tgactttttt
    19921 atctttgaaa ccaaggtcac ggactgcatg gacaaaagtg acacttaagg caagcaaggc
    19981 tactgcatca accgtgttat aaccttctag gacaccattt gttaaagcgt ttgtttggta
    20041 agtatctgca gcagattgat ttagatttcc cattgggtgg aataaagaaa cgacaaaaat
    20101 gattgctaat aatgcaagaa acaaggagtt tagatacttt ccgacgtatt tgaccaaccg
    20161 tgtgggatgg acagtaagga aataagcaag taaaaagaaa agagcagaga ataaaaacat
    20221 acctaatgaa ttatattttt caggcaaaaa tggtttagca gccatttcaa aagcagtagc
    20281 agctgtccgt ggtgtaccga aaaatggtcc gatcgtcaaa tgaacaagga ttaagaacaa
    20341 ggcagcatac cattttccga caggtttagc taagtcatac agaccatcac tttttgtcac
    20401 tactacagct aagatagcta gtaatgggaa aagagcgcct gagatggcaa atcctacgcc
    20461 agcactgacc cagtttgcgc cagccatttg acctaagtgg acaggaaaga ttagattacc
    20521 tgacccgaaa aacatcccga agataagtga actgaccatc aatagttgtt tccatgaata
    20581 agtttttgtt tcttccataa atttttcctc caataattat cattttgatt gacgatataa
    20641 acgttgcagc aattagtaat gccactaata tcagattcca tgaaaaccac caccttaaaa
    20701 tataaaaaaa agcccttttc cacttgggaa aagggctcta gattctagaa cggtaccacc
    20761 ttttttcgct taaaaaagct tcttcattca cggacgcttt ttgataaagt tatccgctag
    20821 cctgataatg gaggcagcca caatgatcta cgttttcgac attgactcgg aaatgatgtt
    20881 cgtctattcg atttattgtc atttctcact tacatgactc actgggaata aatcgttgaa
    20941 tagcctactg ttttcctcga cgctttgctg tatgtttatt tgttgacgta ataatacacc
    21001 tgtttttttt gaaatgcaag aatattttaa ctattttgtt ttcttttttt gaaacaagaa
    21061 aaatacctag agaatacctc tgaatgaaac ggaatatttt gttctccact ttcatataac
    21121 ttacattctc agattctttt tatcaaaacg agacctttag cgaatggaaa cagctatttt
    21181 ttaacgtttc ttggtacgta tggttaaacg actcttttac aaccttttct tatttgctat
    21241 atagtttctt ctgagtatgg taaaatagga aagaatgaat cgaaaaaaag gggatgtcta
    21301 tttttgacgg aagagtctag ttctttagag attagattga cagctgctga tgatgtcagc
    21361 atgcttttag gtgcacacga caagcatata aaactgatcg aggaaacaac ggaaacaacc
    21421 atccatacac gtggagaaat cattcagatc attggtgaac aatcccagat ttccttggct
    21481 gcctcagtca ttcggacatt acaggaattg atcaaacgag gaatccacgt aagtacacca
    21541 gatgtcgtga cggcattgaa aatggggcaa aaaggtacat tagattattt tgttgagatg
    21601 tatgaggaag agatcgtcaa agaccgtaat ggaaaaccta tacgggtaaa aaacagcggt
    21661 caaaagaaat acgttgaatc ggtagccaaa catgacatcg tatttggtgt agggccagcc
    21721 ggaacaggga aaacgtttct tgccgtagta ttagcaattg ctgccctaaa aaaaggcgaa
    21781 gtgcaaaaaa tcattttgac gcggcccgct gtagaggcag gggaaaacct aggctttcta
    21841 cccggggatc tgaaagaaaa agtggatcct tatctgcggc ctgtttatga tgctttatac
    21901 caaatttttg gattggatca tacgaaccga ttgatggaac gaggcgtaat cgaaatcgca
    21961 ccattagctt acatgcgggg gcggacattg gatgatgcat tcgttatctt ggacgaagca
    22021 caaaacacga cagtcgctca gatgaaaatg ttcttgaccc gtctcggtta tcaatcaaaa
    22081 atgattgtca atggggatac aagtcagata gacttgcctc gagggacgac aagtggtctt
    22141 gttcatgcag aacgaacact aaagcaaatc aaaaaaatcg attttgttaa ttttgaagca
    22201 agtgacgttg ttcggcaccc tgtagttgcc gaaatcatca aagcttatga aaaggcggat
    22261 cttcatcaag aataagcttt gcttaggagg ataagcacat gttgaataaa acactgcaga
    22321 aactacaaga aaaactcgga aaggcagcat tgcctttcct tctgttcttg ttttttatca
    22381 ttgtctgcgg cgttacattt agtagtgtca aacaaaaggc caatgatttc agagaaggcc
    22441 aagtagcaga agagagtatc cgtgcgaata aaacgatcga gaacacggaa gaaaccgaac
    22501 aaagaagaaa actggcagca gaagcagtga ctccagaata tacttatcaa aaagatctgg
    22561 cagatgacca gaacaatcgg atcaagcaat tattcgaatt gatcgataag acgaatgata
    22621 ccatcaacaa atcttataat gacaaggtag ataaggcgaa ggaagatgaa aatatcccga
    22681 aacctactac agaagagcgg attgctacac tgaagaaaaa ttttgaaaac gtgaatgcag
    22741 aaaacgttgc gttttaccaa aaactgccga acaattttta ttcgacgata tttgaaatga
    22801 ctgaaacgga aattcacacg gttagggatg aaagtttgaa gctcattgac gaacagatga
    22861 gtaaacaagt tcgtgaaagc gaattggaag cttttaaaca agaagcagaa gatcagattc
    22921 agtatttgaa tgtcacaaca gagcagcaac aaatgattcg ctacttagtg gatcaaggca
    22981 ttgtagtcaa tgatgtattg aatgagaaaa agacagaaga attaaaacaa tctgcacgag
    23041 aagctgtaca accagtgatg atcttccaag gagaaatcat tgttcgcgaa ggaaatcaaa
    23101 ttgatgcttc agcgatgaaa aaattggaat tactaggatt gacgaatcaa acgacttcga
    23161 ttttcccact cattgccatg gttttagctg ttttgcttca aatcggcgta ctgatttata
    23221 attcacttca attccaaaat gcaggagaaa gaacaaaata cgtgcttttc tatgtgacag
    23281 ctatgtcagt cagcatagtg ctgatgaaat ttttccaatt attccaaacg gaacaagcta
    23341 cttatatccc gctgttttat cccgctgctt ttgcaccact tgttttaagc tttttcttga
    23401 accgaagagc agggatcatg gctggtattt tccaagcagt atctgcactt ttcatttttt
    23461 atgattcgat tggcacgaac tttctaacga ttatcttgat gtcttatgtt ttctctgggc
    23521 tcatggcaac gattgtcaga cgcaaacgga tctcagaaca aggattatct gctgccatgt
    23581 gggtcattat ttttcctgtg atgatggatg tcattttgat cgtctatcaa ggaatgagct
    23641 ttggtgatgc aacgacttgg ttaatgcttg tctgcgggtt cactggtgca ctcttctcat
    23701 tcttgctgac gatcggtcta cacccatata ttgaattgat ggtcaatgat gacagtgtaa
    23761 ttgtattaaa tgaactcagc aatccaaatc atcctttatt gaaacagttg ctggaagaag
    23821 cgccaggtac ttatcatcat agtatgatgg tagctaatct aagtgctaac gctgtagcag
    23881 aaatcggcgg acgttctttg ctaactcgag tagcttgcta ttatcatgat atcggcaaga
    23941 tcaaacatgc tagctttttc gttgagaact tgccttcagg agcggaaaac ccgcacaatt
    24001 tcttattgcc agaagacagt aaacatatta tctttggaca tgtgacagat ggagccaaaa
    24061 tattggaaga ttataatatg ccgcaaatgg tgatcgatat ttgcaaacag catcatggaa
    24121 ccacgctaat gcgttatttc tacatcaaag cgaaagaacg caatccggaa gtaacagaag
    24181 agcaattccg ttatcctgga ccaaaaccgc aaagtcgtga agcagggatc gtcaatattg
    24241 ctgacagttg tgaggctgca gtacgggcaa tggatcatcc gacgagcgaa aaaatcgaaa
    24301 gttttgtcca taatcttatc gaagagcgta tttccgatgg tcaattagac gatagtggac
    24361 tgaccttgaa agaaatccga aaagtggaaa aatcattgat cagcggttta agtagcacct
    24421 tccattctcg gatcaaatat cctaaaatga aaacagaagt tgagaagata aaggaagaac
    24481 aagaagaata gaaagaagcg atgtataatg gatattacct ttatggatga aacaaaccaa
    24541 gtctcagaag agaaaatgaa agaaatcgat gacttgctgc aatttgcagc atcttattta
    24601 aagctgccag aggaaacaga aatgtctgtt actttcatgg acaatgcggc aatccaagta
    24661 atcaatcgtg attaccgtgg aaaagatgca ccgacagacg tcatcagttt tgctctggaa
    24721 gaagaaggcg aagacgaaat cccagtgatt tttgaagatg gagagaatcc tttgcctcgt
    24781 gtactaggag acatcatgat ttctattgaa cgtgctgctg aacaagcaga agcttacggc
    24841 cattcatatg atcgggaact tggcttttta gcggtacatg gattcttgca tatcaacggg
    24901 tatgaccata tgacaccaga agatgagaaa gaaatgtttg gtttacagaa agagatcttg
    24961 gatgcctatg gactcaaaag ataaaaacgt agagaaaaac aaacatttcc tgatgtctgt
    25021 ggaatttgct gtccaaggag tcaaaaccgt ttttgaggaa gaacgcaata tgaggaaaca
    25081 tgttgcgttc ggtatccttg ctttatttat gggcgtgatt ttccagcttg atcggataga
    25141 gtggttatgg ctgcttttag ctgtttttct cgtttggata gtagagatca tcaatactgt
    25201 ttttgaaaat gtagtggaca tgtttacgga ttttcatttt catccgattg ggaaaaaaat
    25261 caaagatatg gcagctggag cagttttagt gaccgcttgt tttgctgtca tcattgggtt
    25321 gattttattt gtccctaaaa tatatcattt gttgtttaat taaaaaggag aacgtatatg
    25381 ccagaacata aatcagggtt tgtcgcaatc gtcggccgcc cgaatgtagg aaaatccaca
    25441 ttattgaacc gaatcgtggg tcaaaaaatt gccattatga gtgacaaggc acagacaact
    25501 agaaataaaa tccaaggagt atatactaca ccagaagctc agctgatttt tatcgataca
    25561 ccaggaatcc ataaaccaaa gcatcgtcta ggagatttta tggtagaagc agcttacagt
    25621 gcgttgaaag aagtggatgc agtcttattt atgatcagtg ctgatcaaaa acgcggccgg
    25681 ggagacgatt ttattattga acgtctaaaa aacgtgcatt ctccagttta tctgattatc
    25741 aataaaatcg ataagatcca tccagacgag ttgctgggaa tcatcgaaga ttattcgacg
    25801 cagatgcctt ttgcacaagt gattccgatc tctgctacag aaggaaacaa tgtcgaacgc
    25861 ttaatggatg tattagtcag tgaaatgcca gagggcccac aatattttcc agatgatcaa
    25921 gtgactgatc atcctgaata ctttatcgtt tctgaattga tccgtgagaa agtcttgttt
    25981 ttaacacgag acgaagtgcc tcattctgtc gcagtcgttg ttgattcgat gaagcgaaac
    26041 gagaatgata aaatccatat ccaggccacg atcatcgtcg aaagagatag ccaaaaagga
    26101 atcattatcg gcaaaggcgg aaaaatgctg aagcaagtag gaacgaaagc aagaaaggat
    26161 atcgaaaatc ttttaggaga caaagtattt ctagaacttt gggtcaaagt ccaaaaagac
    26221 tggcgagaca aaaaagtcta tctgcaagac tttggctacc gaaaagacga atactgatat
    26281 tctgaacttc ttataggtta agtatagaaa taaactggat aaaaatccgc acgttgagaa
    26341 aaacggcgga agatcgaaac ataaataatc tggatcggca gaatctgctt ttccagattt
    26401 attttttagg agggagaata tgagccagct tgcagaatcg aaaggcttga ttttatctag
    26461 ccgtaattac aaagaaaaag ataaattagt caaaatcttt acggaatctt ctggcaaaat
    26521 gatgttttat atcaaaggaa tccatcggca aaatcagcca ttagctccgg ctttgctccc
    26581 ctttaccgaa gcagtctata tcggtaattt tcgaagtgaa ggtttgtcgt ttttaagcag
    26641 tgtcaaagac gtccatgcgt ttcggaacat ccaagaagat atctttttga gcggttatgg
    26701 tacctatttg ctaaatctag tagatgcagc aatcgaagat catcaatatg acccgcattt
    26761 attccaattt acgcaacaag ctctgcagcg gatggatcaa ggagatgatg cagaaatcat
    26821 cacgaatatc tttgaagttc aaatactgca acgcttcgga atcgcgccaa tttggacgca
    26881 ctgtgtcgta tgcggggaaa caaaaggaaa atttgactat tcttccaaat ctggcggtgt
    26941 gatatgcgag aaacactggc caatggacga acaccgttat catgcagatc ctcgcgctgt
    27001 ttatttcgtt cgaatgtttt cggctatttc ttatgataag atcagtggaa tccacttgaa
    27061 agaagaaacg aagcaggcaa tccgtgacct cattgaccag ttgtatgatg aatatgtcgg
    27121 tattcatcta aaaagcaaaa agttcattga tcaaatgaag tcttgggcac acgtattaaa
    27181 gacgccagag aaaaatatgc ctgaaaaaga gatacctgaa aaagaagaat aaatgaaaga
    27241 tacaacaaaa aaatcaaaac tatttgacaa atacagggac ttccgtctat tattaaccgt
    27301 agattaaata gatcgttcac tgagaggatc tattatataa acaagaaaac tgcaaaatga
    27361 atacgtacat tgaccaagat cagtaaaaaa cacgtggttt agcgagttcg ggagagtgga
    27421 agccggaccc aaacgatttt tgaagaggca cttgcgagta cgataaatga agctgccgaa
    27481 tctttattcg gaagtagggt ggaaccgcga aattattcgt ccctatgtct gtaatcagac
    27541 atagggactt tttgtcgttt tctttcctgt attcttattg acagcaacgc ttaaaaattg
    27601 aaaggggcaa aacagatgag taaaaaattg accgtccaag atatgatttt aacattacaa
    27661 aaattttggt catcaaacgg ctgcatgctg atgcaagctt atgacacaga aaaaggagca
    27721 ggtacgatga gcccatatac attcttacgg gcaatcggac cggaaccatg gaatgctgct
    27781 tatgtagagc catcccgccg accagctgac gggcgttatg gagaaaaccc aaaccgtttg
    27841 tatcagcatc atcaatttca agtcgtaatg aaaccttcac ctgaaaatat ccaagagctt
    27901 tatttagaaa gcttgcgtct tttaggaatt gatccattag aacacgatat tcgttttgtt
    27961 gaagacaact gggagaaccc atcgatgggg tgtgccggtg tgggttggga agtatggctt
    28021 gatgggatgg agatcacaca attcacgtac ttccagcaag tcggaggact accttgtaaa
    28081 ccagttactt ctgagatcac ttatggacta gaacgtcttg cttcatatat tcaagaagtt
    28141 gaaagtgtct atgatctgga atgggctgat ggtgtgaaat atggcgagat cttcaaacaa
    28201 ccagaatatg aacattccaa atattctttt gaagtaagtg accaagactt gctactaagc
    28261 aactttgacc gttttgaaaa agaagctaaa cgctgtatcg atgaaaatct tgttcatcca
    28321 gcgtatgatt atattttgaa atgcagccat acattcaatt tattagatgc tcgcggtgca
    28381 gtatccgtaa cagaacgagc aggttatctt tcccgtatcc gcaacatggc tcgtgctgta
    28441 gccaaaatct ttgtggcaga acgcgaaaaa ttaggattcc ctttattgaa taaaaacaca
    28501 gcaaatccag aaaacatgaa ggaggctgaa taagatggca aaagacttat tacttgaaat
    28561 cgggctggaa gaaatgcctg ctcatgttgt cacaccaagc atgaaacaat tagaagaaaa
    28621 aacagcaaaa tttttagatg aaaaccaatt gacttatgat acgatcgaaa cgttttctac
    28681 accgcgccgc ttagcaatca aagtaacaaa cattccagaa cgtcaagcag acagcgaaga
    28741 agaagtcaaa ggaccagcca aaaaaattgc tttggacgca gatggaaact ggacgaaagc
    28801 agctgaagga tttgtccgcg gacaaggtct gacgacagat gctatcactt ttagagaatt
    28861 aaaaggcgtg gaatatgtct atgtaacgaa atacactcac ggcaaagaag caaaagaagt
    28921 attgacaggt ttagcagatg tcattaaaag cctcactttc ccagtaacga tgcactgggc
    28981 agaatacgat tttgaatata ttcgccctat tcactggatc gtggcattgt tagatgacga
    29041 aataatcccg tttgagatct tggatgtcaa aacagacaga gcttcaagag gtcatcgttt
    29101 cttaggcgaa gatgtgacat ttacgcatgc aaaagaatac gaagaaaaat tgaatgaaca
    29161 atttgttatt gcttcaccgc aaaaaagaaa agaaatgatc atcacacaag caaacgaatt
    29221 agccgaaaaa aatcactgga tcattgatct agatgaagat ttactagaag aagtcaacaa
    29281 tttagtcgaa tatccaactg tcttttctgg cgacttcgaa gaaaaatatc tatctgttcc
    29341 tgaagaagta ctagtcactt ctatgaaaga acatcaacgt tatttcgaag tacggaacga
    29401 tcaaggtatg ttgcttcctc attttatttc tgctcgtaat ggcgatcggg taaaattgga
    29461 aaatgtggta cgaggcaatc aaaaagtatt gacggctcgt ttagaagatg cggaattctt
    29521 ttataatgaa gacaagaaag cttcaatcga ccaatacgtt gaaaaattaa aaactgttac
    29581 tttccatgaa aaaatcggta gcatctatga gaaaatgcaa cgggtacaag tcatcgctcg
    29641 catcataggc gaacaagtag gactatctga ggaagaattg atggatctgc aacgcgctgc
    29701 tgaaatctat aaatttgatc tagtaaccaa catggtagga gaattccctg aactacaagg
    29761 gatcatggga gaaaaatatg ctctgctgaa aggcgagaaa ccagccgtag caacagcgat
    29821 ccgtgaacat tacatgccta tatccagtga aggagattta cctgagacta cagtaggttc
    29881 tgttttagcg attgctgata aattagatag tatcttttct ttctttgcag ttgggatgat
    29941 cccaagtggc tcaaacgatc catatgcttt gcgccgtcaa gcatatggtg tcgttcgaat
    30001 catcgaatcg aaaaaatggg cctttccttt gtctgttctg caagaaacga ttagtgaagt
    30061 tatcagtaaa gatacggatc gttttggcat tggcttgtca gcgggacaac aacaggtgat
    30121 cgactttatc aaaggccgtc tgcgccaatt attgacaacg aagaatatcc gtcatgatgt
    30181 catcgaagct gttttgaatg cagaacaaaa agatctgaca aaagtatttg cagcagcaca
    30241 attgttcaag cagcatcttg cagatgaaga cttcaaacca tcgatggaag ctttgacacg
    30301 tgtcgtgaac ttagcgaaaa aagcggagct tgaaaaacaa tcagaagtag accctgaact
    30361 gttcgaaaac gaagcggaga aagaactgca caaagcagta gaggcaatga aaacaagctt
    30421 tgctgaccaa acgatcaacg aaaattatga tcagcttgta agccttcgcc cactgatcga
    30481 aaattatttt gatcagacga tggtcatggc agaagaacca gcagtacgta agaaccgatt
    30541 aacgcaatta agtcaaattg ctgccatggc tttgtcacta gcaagtttag atcaaatcat
    30601 cacaaaataa tttctaatat gtaaataaac cagagaacag gcacaaaata ggctatttct
    30661 ctggtttatt tgttataaat ataaataact attattaatt caatgttaat ttttttgtta
    30721 ttttattttt tgtgtaactt ttaaaaacac ctatgaaaat taaggaaata aaaatgaaat
    30781 cgattaattg ttatcttatt aatgttttat ttacttttaa atcgtaaatt gccctagtca
    30841 agaaaatagt ttgtggtatg attatatagg gaaaacttgt ttacaaatat ttctgtgaat
    30901 atattaattt aattatgttt tttaaaataa aaagctgtca tttttatgta tgtgaattat
    30961 atcttaattt atctatcatc aatacttagg agtgaatcta tggaaaagcc attcgtcaag
    31021 tcattgactg ctgtggcggt aggtgcaggt gctattgcga tctgtttgtt tggttaccat
    31081 atcaataatc agcggcaaca tcagcaacgg atcaattatg cagaatctgc catcaccaat
    31141 caaaaagaca ccttgacttc tttatcaaaa gaagtagaca agctgtatag tacaaaagaa
    31201 aaaaattttc taaaccctga aataacagaa gaaacaatca caagtttgtc aaataagcta
    31261 tcctctgtca aactttcagc agatgattac gacatcaaag aatcagaatt gcctaaagaa
    31321 gctgttgcaa tccaagatga gaagaaagca atcgtgacac agttagatag tgcagaatca
    31381 aaactgaaga tccagacagc tgtcaacgat ttatttacta aaaatgtatc aaactggcag
    31441 caagctgtag acgatgtcgt catcaaagaa aaggtgacaa gtgcagatgt cgctcgtgta
    31501 cgtgaaaata tgagcttttt taaagatagt ccttggaaaa cggttgttat gcaatatcta
    31561 ggattcgctg atactcagat cgcgcaagtc acgcaactag atcagttatt cgatacgatg
    31621 ttgaaggatg gtcaagtgac tgccaccgct acttacgatc aatatttgac ggcgctcagt
    31681 caaatagagc agatccggaa tgaaaaaata agcgcagcat acgcaacaaa agcacaaact
    31741 gttgctcagc aaatgggcta tagcaatata agttattgac agttaaaacg ttgattcaag
    31801 caaggttagc aaacggagga aactatggca agacgaagaa gaaaatcaag agggaaaaaa
    31861 atatttctga ttattttagc agttcttatc gtattagtat tagcaattgt aggagtagga
    31921 gcaaaattat atctggatct ctcacattct attgagaaaa cttacgaatc agtggaacga
    31981 acccaaggag aacgaacgaa accagttgat ctggacaaac aagaatcttt ctctgttcta
    32041 ttgatgggca ttgatactgg agatttaggt cgggtcgatc aaggaagatc agatacgatg
    32101 atggttgcca cagtcagtcc tgaagacaaa cagacaacga tcgtcagcat tcctcgagat
    32161 acgtatgtcg acatcgtagg tcgtgacaca aaagacaaga tcaaccacgc ttacgcattc
    32221 ggcggagctg ccatggcgat ggatacccta caaaaatatg tagacatccc aatcgatcac
    32281 tatgtctcta tcaatatgaa agggctaaag gaactcgttg atgcagttgg tggtatcgaa
    32341 gtcaataatg acctcacttt ctcacaagat ggctatgact ttccaatcgg taaaattaca
    32401 ttgaacgggg atcaggcatt atcttattct cgtatgcgtt atgaagatcc aaatggtgac
    32461 tatggtagac aagagcgtca aagaaagatc gtagaaggtg tagcaaaaaa agtattgagt
    32521 ttaaacggtg tcagcaacta tcaatccgtt ttgaatgctc tagagtcgaa tatgaaaaca
    32581 gacatgagct ttgatgaaat gaaaaaaatc gctttagatt atcgggaggc atttggtacg
    32641 atcaagcaag atcagctgca aggagaaggc ttcatgcaag ataatatctc ctatcaaaaa
    32701 gtcagcgatc aagaacttga tcgtgtgaaa aaagaattaa aagatcaaat gaatctagag
    32761 aataaatagg aaagtggaga aaaaatggaa gagacaatca gcttgaaaga aatttttgaa
    32821 acattacgca aacacttggt aacaatcatc atctcaatgt ttgctggctt ggccatctca
    32881 ggaatcgtaa catttttcat cttgacacca aaatacagtt cacaagcaca attgatcgtg
    32941 acactgccac aatcagacac agcaaatgtc aatgatgtca atacgaacct gcaaatgatc
    33001 aatacgtata aagatatgat cgtcagtgat ttagtactaa atgaagtcaa agatcgttta
    33061 gaaacagaag acaatgtgaa aatgactgct ggacaaatca aagatgcgat ctccgtcaat
    33121 cagtcacaaa attcacaaat gttctcgatc caggcaataa gcacgaatgc agtgactgct
    33181 caacagatcg ctaacacaac ttcacaagtt ttccaagaga acgcaaaaga cgtgatgaat
    33241 gtcgataaaa tctcgattat ttcaggtgca gttgccaata cgacacctgt ttcgccaaat
    33301 aataaattga atctagtgat tggcttagta ttaggaatga tggtaggcgt aggtctggca
    33361 ttcttattcg aattacttga tcggacagtg aaagatgaaa aatatgtgac ggatgcatta
    33421 ggattcccaa tcttaggaac agttccagaa atgtcagcga aagaattgaa cgctggtatc
    33481 cgtaaaaaag gaacagctcc tgcacgacca aaagctacaa acgataaaac agccccatca
    33541 cgcagaagcc gctcaagagt ctaggaggaa gaaaaatggc acgaacacag aaacaaaaag
    33601 cagcacaaac tcatgcagtc agtttgatca cattaacaaa cccatcttca ccaatcgccg
    33661 aacaatatcg tacgatccgg acgaatatcc agtttgcctc cgcagctggt cagcaaatca
    33721 aaacgattgt cgtgacttca tcaggtcctg gagaaggaaa atccaccact gcagcaaaca
    33781 ttgcagtcgt ttttgctaaa tccggtcaac gagttctact agtcgatgca gatttacgta
    33841 aacccgtcgt ctataagaca ttccagctga acaatgccag gggattaagt acagcactta
    33901 gttcatcagg aagtgtagca gatgtaatcc aacgaacgcc agtcgagaac ttgtcgattt
    33961 tgcctagtgg acctaagcca cccaacccat cagaattgtt aagttcgcca agaatggatc
    34021 agatcctaga cgaagcaaga cagttatttg acgtggtgat attcgatatg ccaccagtag
    34081 tagccgtaac agatgcacag atcatgtctt caaaaacgga tggcacttta ttggtcgtac
    34141 gtgaaaatac atcacgtaaa gaatcattga ataaagcaaa agaactgcta gagatggtac
    34201 aagcacgagt tttaggtgtt gtatacaacg gagcagaaca tagcaaagat gctggttatt
    34261 actacggaaa ttaaggaata agaagagagg agacaagaga aatgatcgat ctacattgcc
    34321 atatcctacc aggaatcgat gacggggcag aaaacttaga agcaagtatt gcaatggctg
    34381 aaaaagcgat tcagcaaggc atcacgcata ttttatgcac accacaccac aataatggaa
    34441 aatacagcaa tgaaaaatca caagtcattt ctctagtcgc ttcgttacaa gccgaattag
    34501 agaaaagaca gttgcctttg acgttattgg aaggacaaga agtacgtatt accggaacgc
    34561 tcatcgaaga catccaccga gatgaaattt tatttacaga tttagatgat acatatcttc
    34621 tgatcgaatt tccgacactg gaagtgccgt tatatgcaga acggcttttt tttgagttgt
    34681 tagaactagg aaagacacca gtgatcgtcc atccagaacg caacgcgcat tttcgcgaag
    34741 acccgaatca tttgcttccg ttcctagata tggggtgttt ggcccaactt actgcgccaa
    34801 gttatgttgg ggtatttggc aaagatattc agaaaacagc taaaacaatg gtcaaacata
    34861 atctcgtgca gatgactgct tctgatgcac acggagtctc taagcgcacc ttttacttaa
    34921 aagagtgcta tgagcagatt gccaaggact ttggtaagga aaaagtagta cagatgaagc
    34981 aagttgcaaa ggatctgatc aacggggatg aaatcagtta tccagactat gaagaggtaa
    35041 aaaagaagaa gtttggttta ttttaggggg aattaaaaag tgtttatatt aacaagaaga
    35101 agaaaaattg ccacattggt ttttgtggac agcttgttat taattgctgc aaatattgca
    35161 gcagctaaat tcatgaagcc gtttgtatct ataccaatgg atcttatttt aatctctatc
    35221 ggtttgtcga ttggttttta tttattttat ggtagtttat tcaaagtttt cactcggatc
    35281 aatcgctata caaatttaag agagatcatt gcaattttta gttcactatc tgcaagtgct
    35341 gcctcaagta tcctcatact gctgttcatt aatcggcgat acagtttacg gttagttatc
    35401 tttgcttatc tgctttcgct cttattgatc atcggtagcc gattgatctg gcgtatctac
    35461 atcgaaacaa aaaatatgag atacgtatca gcagattctg ctaaaaatac attgattgtt
    35521 ggtgctggcg aaggcgggcg tattttatac aacagctttc ttggatccaa aacggctcaa
    35581 gatatccacg ttgtcgggtt tgtagatgat gatccaaata aaagaaatac gtatctttca
    35641 ggaaaaaaag tattaggtgc attaaaagat attccggaat tgattgaaaa atatgacatt
    35701 caaatggtaa cgatcgctat cccttcctta tcaagaaaaa aattacgacg aatcttcgag
    35761 ttagtcgaat ccgctcgtgt gaaagtcaac acgatgcctt ctatagaaga acttgcttca
    35821 gggaaaatta gcgtatcaaa attaaaaaca attgacgtag tggatttact gggaagagat
    35881 gaggtaaagc tggatattga atccatcaaa gatcagatca cagacaaagt cattcttgtc
    35941 accggcgcag gaggatcgat cggttcagaa atctgtcggc aaatcattca attcaatcct
    36001 gcaaagctat tgcttttagg acatggggag aactcgatct acttgattga ccgtgagtta
    36061 cgcacgcatc atcaaaattg tcctacagaa atcgtaccga tcatcgcaga tatccaagat
    36121 cgcgagaaaa tcaatgagat catggaacaa tatcatccag atatcgtcta ccatgcagct
    36181 gctcataaac atgtaccact gatggaatat aatccaaaag aagcagtcaa aaacaatatt
    36241 ttcggtacaa aaaatgtagc agaagcagct aaagcagcaa aagtgaaaaa cttcgtcatg
    36301 gtatcgacag ataaagctaa caatcctcca aatgtcatgg gttcaacaaa acgaatcgct
    36361 gaaatgattg tgactggatt gaatgaagaa ggctgtacga aattctcagc tgtcagattt
    36421 gggaatgtcc ttggttctcg cggtagtgtg attccagtat tcagagaaca aattgctcaa
    36481 ggtggtccaa tcactgtaac agactttcgt atgactcgat actttatgac gattcctgaa
    36541 gctagtcgtt tagttattca atctggcgca ttagcaaaag gtggcgaaat ttttattcta
    36601 gatatgagtg aaccagtgaa gattgtagac ctagcgaaaa acatgatccg attgagcggg
    36661 tatagcgaag acgaaatcga aatcattgaa acaggtatcc gtccagggga aaaactatat
    36721 gaagaactat tgttggataa ggaaagaaat gatgaagcag tttatgagaa aatctttgta
    36781 ggaaacatca aaggttactc aatacaaaaa gtgatggatt ttgtcaagag cctgccgcaa
    36841 gacgatgaac aattggctaa agacattgtc acttttgcaa atgcttcgaa tagataggag
    36901 attaaaaatt gaatatttta atattaagtt gtggacgtcg ttgtgaacta gtgaatgcat
    36961 ttaaaacagc attaaacaat aatgaaatgg aaggaaaaat cattggagca gattgctctg
    37021 aactagcacc cgcactatat atgtgtgacg aaaaaatagt attacctaaa gtttcagaaa
    37081 gtaattatat tgaggaatta ataaaagtaa taaagttttt tgaaattaaa ttaattgttc
    37141 ctactattga tactgaatta tcaacattat caagaaataa aaaatatatt gaaaatgaaa
    37201 cagactcagt tgtattagtt tcttcagaaa aagtcatcga catttgtgag aacaaaattt
    37261 taacttctgc tttttttgaa caaaatggtt ttaaaactcc tgaaatttta aactcttctg
    37321 aaattacaaa atttcctgta tttataaaac ctctgaatgg tagttcatct gttaacacat
    37381 ttattgtaaa taatgaaaaa gaattgttgt tttttagtga atatatagat aatcctctta
    37441 ttcaagagta tattttaggt gaagaatata ctatagatgt ttgcttaaac tttgattcga
    37501 caccagtaag tattgttcct agaaaaagaa tagcaactag aggtggggaa atactgaagg
    37561 gtcagattat taaagataga gaactaattg agactacgaa aaagatgttg gaaaaattaa
    37621 atgcaatcgg acatattact attcaatgta taaaaaacga aaagggaata ttttatttag
    37681 aaataaatgc aagatacggt ggaggagccc ccattagcat taaatcagga gctaattccc
    37741 ctgaatatat tataaagatg atagattcaa aaaaaaattt gagatacaga gaaaattatt
    37801 tagataaaat gatagcactg agatatgatc aagcgattta tttagatgaa aaaggaaatg
    37861 tatataatga ttaaagcggt gatctttgat ttagatgaca ctcttgtgtc tgaatatgat
    37921 tatgtaaaaa gtggatacaa atgtgtagct agaagattag cagtgcaaaa aattttcccg
    37981 gctacttttg acgaaatata tagagtcctt ttagatcttt ttgctgaaga tagtaaaaat
    38041 gtatttaatc gtctatatga ctattttgaa attccttata gtaaaaaaga aattaaagaa
    38101 ctggtaaatg tatatcgaga acacaaacca gacataaatt ttttagaaaa tgcagatact
    38161 ttattaacgg aattaagaag tagaggatac aagctgggga ttattacaga tgggtatgct
    38221 ataacccaac gaaacaaatt ggatgctttg aaagtagact atttggtaga ttatatttgt
    38281 attactgacg aattaggccg tgaattgtgg aaaccacacc ctatctcata tcttttattg
    38341 ttagaaaagt ttaatttaaa ggcacaagag tgtatatata ttggcgataa tgagttgaaa
    38401 gattttataa ctgccaaatc aataggaatg caaacaatta aaatagaaag agtaaatggt
    38461 atttacagag aaagcagttt gaagttcaaa agattttacc aagctgataa aaaaatacgt
    38521 tcgttatggg agataaaaaa ttttttggga gtgatttcat gaaaagtaaa agaattctat
    38581 tagcttctcc acatatgagt gaagaaggat atgaaaaaga gtatgtaaaa gaagcatttg
    38641 atacaaattg ggttgctcct ttaggtgcga atgtgaatgg atttgagaaa gaattagcag
    38701 aatacgtggg agctagtcat gctgccgcat tatcttctgg aacagcagct atacatttag
    38761 ctttgaaagc ggctggggtc ggtaaagatg acatagtgat ttgtcagtcc ttgacgttct
    38821 cagctactgc taatccaatt ctctatcaag gagctatacc tgtatttgtt gatagtgatt
    38881 acgaaacttg gaatatgaaa cctgaacatt tgcgaacagc actagaaaaa tatcctaaca
    38941 caaaggctgt attagtagta catttgtacg gtttatcagc taatttagac gaaattacta
    39001 aaatatgcaa agaatacgat gttactctaa ttgaagatgc tgcagaatca ttaggaacaa
    39061 catataaagg aaaatatact ggtacatttg gcgactatgg aatttattct tttaatggaa
    39121 ataagataat cacaacttca ggtggcggaa tgcttgtatc caatgacaaa gaaaaggtgg
    39181 aaaaagtgag attttgggct acgcaatctc gtgagaaggc acgccattat caacacaatg
    39241 aaattggcta taattatcga atgagcaata tcgttgctgg tatcggtcga ggacaattga
    39301 aagtattaaa tgaaagaatt gagaaaaaac gatatattca tagtttttat aaaaaagaat
    39361 tgtctaaatt gtcaaatata caattcatgc cagaaaataa ttggaatgaa ccgaattatt
    39421 ggttaagtgt cataacaata aagggaataa atgcgaatca tcttattgat gagttagaca
    39481 aaaataatat agaagcccgc ccagtatgga aacctatgca tttacaacct gtttttaaaa
    39541 attatgatta tattggcgat gatgtagcag aaactttatt tgacttagga gtatgtttac
    39601 catcagatac aaagatgaca gatgaagatt taaaatatgt agtatctacg attaaaagag
    39661 tgatcaatga tgcgtaaaaa aactttctat cagctttttg ggaaaagaat tttagatatc
    39721 ctattgtcag gaattgctct catcgtttta tcgccgataa tcttaattgt aggtttttta
    39781 gtaagaatta aacttggttc tccaattatc ttcaaacaag aacgaccagg aaaaagtgaa
    39841 aaaatttttt ccatgtataa atttcgtaca atgactgacg aaagagacca caatggagaa
    39901 tatttacctg atgaaattcg actaactaaa tttgggaaaa tgcttagagc aacaagtctg
    39961 gatgagctac ccgaactttg gaatattttg aaaggtgata tgtcgatcgt aggacctcgt
    40021 ccattattag tggagtattt gccactatat agtgagaagc aacggaaaag acacaacgta
    40081 agaccaggat taactggact ggctcaggtc aatggaagaa atgctattag ttgggaagaa
    40141 aagtttgatt tagatgttta ttatgttgat aaaattagtt tctttaatga tcttattatt
    40201 ataattcaga catgtaaaaa agtaatcaag aaagagaata ttaatacaat caataacaat
    40261 atcccagaaa aatttaaagg gagttaaata cagcagctta atgcaagttt tgtgacttgc
    40321 attatattta ggtataaatc aaagcgagta tattagaatt atataacata tgttaaaaaa
    40381 acgtatagct aataaaagta tgattttaaa aatttgtgta gagttttaaa tatactgttt
    40441 caatacgaga aaattataaa aaagtataag gaaaagagag ttatggcaaa gtattataat
    40501 aaaaaaattc ttataatggc aaacaacgat gatggtcttt accgttttcg aggaatgctc
    40561 ataaaaaact tagtagatca aggtaatgaa gttattgtat ctcttccaaa gggcaagaat
    40621 attcctaaat taattgaact tggatgtcaa attattgaaa ctccaataga tagaagagga
    40681 attaatccaa aaactgactt taaactattt tttaactatt gtaatatttt gaaaaaaata
    40741 aagccagata tggtcattgc ttatactatc aaaccaaata tatacggtgg attggcatgt
    40801 cggttaagaa aggtttctta tgcattaaat ataaccggat taggaacggc atttcaaaaa
    40861 aagggggttt tgaaaagtct tattgtattt ttgtatagat tagcagctaa aaaatctaag
    40921 gtcatatttt tcgaaaattt tgaaaatatg aaaacatttc agactttaca aattgctaaa
    40981 caaagtaaat acaagctatt aaacggtgca ggagtagatg tagaacactt tagttattta
    41041 gaatatccta aagatgagca agttcatttt ttatttattg gaagaattat gaaagagaaa
    41101 ggtgtagatg aactttttga agcaatgaaa aacttatata gtgaagagaa aaattgtgta
    41161 cttgatgtcc ttgggtattt tgaagaagat tacggcataa aaattgaaaa atacgaaaaa
    41221 gagggatggt taaaatatca tggatatcaa tctgatattc gtccctttgt agaaagagca
    41281 cattgctttg ttttgcctag ttggcacgaa ggaatggcaa atactaacct tgaatcagca
    41341 gcatcaggga gaccaattat tacaagtgat atcccagggt gtaaagaagc agttattgaa
    41401 tcgaagtctg gttatttatg tgaaagaaaa aatagttgta gtctctataa ttcgatgaat
    41461 aaatttctaa aattatcata tgagcagcgc attaacatgg gaaaaatggg gagaaattat
    41521 atgattaaaa aatttaataa gaagaaagtt gtcgatgaaa caattaaatc attatttagt
    41581 taaaaagata tgttttgcaa agtatgtgat agaaaagagg gattctgtgg cttcagaata
    41641 gatatcaaag aattggcaaa agtttctgat atttttttat ttactacatt acaagaagga
    41701 atgccaagat ctatgatgga agctatggca agtggattgc catgtatagc aagtaaaatc
    41761 cgaggtaatg tagacctttt agtggaagga aaaggtggat atcttgttcc agctaaagat
    41821 gcagaattag tagcagagtg tttgagagaa ctaatcaata ataaatctct tagaaagtat
    41881 atgggaaatg agaacctttc cagaattaaa gaattcgagg ttagtatcgt aaaaaaaaga
    41941 atcaaagaaa tatatgaaga agttataggt gagagtgtaa aatgaaaaat ccaatgtttt
    42001 caataatagt acctatctat tgcgttgaaa aatatttgaa agattgctta gattcaataa
    42061 gaaatcagac atttaaaaat tttgaagcaa tactagttga tgacggtagt cctgacgaat
    42121 gcccagaaat atgtgactat tattcccaaa tagatggacg tttaaaagta attcataaga
    42181 aaaacggtgg aataatagat gcacggaaaa caggagtcac tagtgctatg ggagagtata
    42241 tagtttttct agatggtgat gattggcttg caaatactta tttagaaaaa tatgcggaag
    42301 taattactaa gtacaatcca gatataatat gtagtgggta ttttgcatca cgttccaaca
    42361 aaattagaaa aagagaattg tcttgctcgt ttggatatta tgacaaagat aaaattataa
    42421 atttgattta tcctaaatta attgaggatg aacatggaga gtattttaga ccacaattat
    42481 gggcaaaagc ttttagaact actctgtaca aggaacaaca acaagtatct gggcaagtta
    42541 gtgttggtga agatcatgca tgtacaaaac catgtattta ccatgcaaat tcgatatata
    42601 tgatggaaaa atgtttatat tattacagaa taaacgaaaa ttctataaca aaaaaaccac
    42661 aaccatatta ttgggaagga ccaaaggcta ttggagagca ttttgaaaag cagattgata
    42721 tgaataagta tgattttcaa gatcaagtat atagaaatgt tacacacaat ttatttaatg
    42781 ttgctgtttc acaatttaat aaacaggaca aatatttaaa tataaaaaaa gatattatac
    42841 aaaatctaag tgacgaatac tatactagag ctatttgtaa atgcaaatat aaagataatt
    42901 ggaaaggaat tagtgctaag tttgcattga aaaacaaatg ggtattttta atttatattt
    42961 ataacaaatt gataaagagg taataataat gtcagttaag attagtgtaa ttgtaccttg
    43021 ttataatgtt gaaaaatata ttgatgagtg tataaatagt ttgataaatc aaacattgaa
    43081 agatattgag attattttgt taaacgatgg ttcaacagat aatacgttgg cgatattaaa
    43141 gaaatatgaa aagcttgatt ctagaataaa agtttacgaa cataaaaata tggggttagg
    43201 gccaactaga aatcgaggga tcaaaatagc taatggagaa tttttggctt ttgtggattc
    43261 tgatgatttt gtttccaata ctatgtttga aagtttatat aattgtgcaa ttgcagagaa
    43321 tgcggacatt gcaattggag aagtaggcat tttttctgat agagaaatag aaagagtaaa
    43381 aataagaaaa agtctaacga acttaaaaac aattgaatta gcaacatata acaagaaaga
    43441 attttttaag caattctatt tcaatcgttt atattcacat aatgcttggg ataagatata
    43501 tagacgtagt ttagtattag agtttaattt atcatttggt gataacaaaa taatttttgc
    43561 agaagataat tggtttcaat tacaagtatt tatgacaaat acaagaatct gtttcgtaga
    43621 taaattgtgt tattattatc gccaacaaaa taattctata atgcataagc caaaaagtaa
    43681 tttggttttt agacatggaa atatgattgc tgattatgaa aagttgataa ggcaaaatgg
    43741 aaacaacata atagataaaa aagcttgtat gttggttgca tttgatgtac taattatgga
    43801 gatttttaat caaaaaaacg ttggtggaac atgtgaagat tataagaatg cattagtttc
    43861 tttgaaacat cataaaatat tgagagaaaa tatttcaaat atagttagaa tgaaagcata
    43921 tgaacttgaa cctaatatga gaaagaagtt agcccttgtg accattagta taatgtttaa
    43981 ttttaaaatg tataaaacag cgtataatat gctctggaga atatataatc gataaagagg
    44041 taggaaatat gaggaaattg acctttgtga taggaattat gggaaaagga ggggcagaac
    44101 gagtaattgc gaatttggca aataatttta ttcaagataa ctgggaaatt gatattataa
    44161 ctatatatgg gaatcggcaa gactatgaac tgaatagaaa aatacaggta catccaataa
    44221 tatgtaaaag ttcgtttcgt gcatttagac ctttggaacg ctttaaggaa cttaggaaaa
    44281 aaataaggga aatacagcct gatctggtta tttcgttcct tgctgatgta aatatccatg
    44341 tcattatttc attgttagga gtaaaacaaa aattaattgt ttctgaacga aatgatccac
    44401 aacggaatcc agaagaacca tggattagga aaattagaga ttttctttat aaaaatgtag
    44461 atggaattgt ttttcaaaca ccagacgcaa aaaaatattt tagtaagatc aatgataaaa
    44521 aagtaaaaac aattataatt cccaacccaa taaaggaaaa tttaccttat tataataaaa
    44581 ctacaagtag taaaaaattt attactgcat gtagattgga taaacaaaaa aatttgccct
    44641 taatgattga tgcaatagga aaacttattc atgaaggata tgagtgtgaa ctggatattt
    44701 atggagaagg gggattaaaa accgagcttg aaagttatat caaccataat ggattaacag
    44761 aatttgttca tctaaaagaa tttacaaata aaatacatga aaagatgcaa aatgcggcag
    44821 gatttgtaat ttcttctgat tatgaaggta tatctaattc tatgttagaa gcactggcta
    44881 ttggagtgcc agttatcgct acagattgtc cagtaggtgg cgcaagaatg tatttaggtg
    44941 atagaaatga aataggtcat cttgttgaat gtaataatct agataagtta acagatgcaa
    45001 tgcgtagggt acttttggat agagaaagtg tggtaagaaa agcgcaaaaa ggaattaaac
    45061 taagaaaaga actgacatct aaaaatattt caaatatatg gtacgaatat ttaaaccagt
    45121 tcttttaacc aaaaggagga tattgtgtga aagaaaaaat aaatatattg atgttttcgt
    45181 taacgttagt cgcgtttaca atattttgcg ctttttcatt aaatcagaac tattggctaa
    45241 attggcttgg aatattgatt tacttatatg caatctgtac atggcattgg agaaaaggag
    45301 attcaatatt ttcattatac acgatttttt tcactctttt tttattattt agttatgggc
    45361 aatgcattat gtgggcattc ggtattggaa cagatcgtgg aatcggtaca acagtagtag
    45421 cttatggtac ggggattatt cctagtgaat cagatatgat aatggtaaaa tggtattctt
    45481 gtatttctat gtttgtattt cacataggag cactcttatt tacgagaaaa accacactaa
    45541 gaaaagttag ttggtatgaa tctggagatg ctgatgccga tagaaagttt ttatttaaaa
    45601 tagggtgtat catttctata atagtagtac cgatagtttt tgtttctaaa ttactagagg
    45661 tacgtatagc attagtccat ggttataatg cattatatta tggtgattat gctacacaaa
    45721 gtggatattt acaaattatt ctatatcttt tttttccagc cttaatatgt ttattaattg
    45781 gtagcaactt ttcaaaagta ataacgagat ttgtttttat tatttttgct ttatattctt
    45841 tattaggaat tatgtcagga gacagaggaa gttggttgta tagctctatt atactcatat
    45901 gggcatacac tcaatataaa ggaaccttta attataaaaa attaataaag tggcttattt
    45961 tagctgttat aggaatatat attctaaacg taataacgaa agcacgtgat ggtggaggac
    46021 taagtaaact tactttaaaa gattttacat ctgtatttga ttcagatgat tctcctttag
    46081 ttgattcttt ttttgaaatg ggggggacta tgagtattat aacttttttc ctaataagtg
    46141 gtaatggaat atatcccttt gctaatactt atttgacctc actcttaggc tctatatcaa
    46201 caagaatgct atcaatgttt ggaataaagt ttgttttatt agctgattgg ttttctcagg
    46261 attatttagg aatcacttgg gggactggat tctcaatgat tgcagaagcc tatgtcaatg
    46321 gtggatacat tgggggtata gtctatattt ttattattgg tatagtcatc ggtaaaatcc
    46381 tttctaatag tatagacaac caagatattg aaaatcatcc tatgaagatg tttttggcta
    46441 taactacagc aaatattata atgggttttc ctagagctgc ttcatattta attgtgaaaa
    46501 attttgtgta tggtgtttta attatattgt tgataaactt tttcctacag caatttaata
    46561 aacgtcttta atatttaagc ttaataaaaa gataaaacaa gtcaggagtt gcaaaaatgg
    46621 aaagaactgc tcggctcaaa aaaaacacta tttgggctct ggtgtttcaa ataacttcta
    46681 ttgtctgtgg tatgatcttg ctacgtttga tattaacaaa gtacggatcc gaggttaatg
    46741 gaatgattag ctctattaac caatttctac aaattatttc ttttttacaa ttaggagtag
    46801 gcgctgtaat gcaatcaact ctatacaaac cactagcaga aaaggataat ttaatgataa
    46861 gtcaaatctt agcttctgga gggaagtttt atcggcaaat tgcatatatt ctactagtat
    46921 acgtgggttt gttacttgca gtctattatg ttctcgttcc taatgaattt gggagatcat
    46981 atacaatggc aatgattgca acattaagta ttaattcatt tgctcaatat tattttggta
    47041 ttgttaatac tttgttatta agtgctgacc agaaaattta tattacgtat attgcacaga
    47101 caatagcatt tatttctaat acagttgcat gtgctttatt aattagtctg aacacagaga
    47161 tccttatggt aaaacttatt actgctataa tttatcttgc ttgtccaata tattatagat
    47221 ggtatgtgga tcgaaactat aatataaaga ggaatgtgtc atatgataag gaaccgatcc
    47281 ctcaaaaatg gaatggggtt gcacaacacg tagcttctgt tgtactagat agtactgatg
    47341 ttgtagtgtt atctatattt tctaacctga tatatgtatc tatatataat gtgtacaatt
    47401 tagtaatata cggagtaaaa cagctattca tggctatgac aaatggcgtt caggccttac
    47461 taggggaact ttgggtcaga aaagaaatag aagttcttta caaaacattt gcatggttcg
    47521 aatggattgt acatactttg acagttttta tttttggctg taccggtata ctaatcgttc
    47581 catttattca agtatataca agaggagtaa cagatgctaa ttataatcaa ttatcattcg
    47641 cagctttact tgtaactgct aacgcacttc actgtctgcg tacaccttat catgtaatga
    47701 taaaagcagc tggtaaatat aaagaaactc aaaatagttt tataattgct tctttgttaa
    47761 atttaggttt atcattaatt ttggttaaac cactagggct agttggagta gcattaggat
    47821 ctctaatttc aatcacatat catacacttt ggagtgcaaa ttataattca aaatatttgc
    47881 ttaaatggcc gatgaaaaaa ttctataaac agttatttgt aaacatctta actgtagttc
    47941 tttcttttgg ggcgacatca caattgaaaa tgatgtcaat cacatatttg gattggattg
    48001 ttctcgcaat taaatgtgca gttattgtat ttatatgtat aatcctagtt aatgttttat
    48061 tttatagaag atatgtagta aaaataatta gtaaaatcat cgtaaaaata aagaaaattt
    48121 aatacacaat aaatgtttta ataaacttaa taaaattata tttgccaaaa ttagacacat
    48181 atattaaatt ttttctttta aggttactta tgtgatcaag aataatttct attcgtttta
    48241 gaataagtta atagataata gaaagaagtg ggttgcttag caatttccta tctgtataat
    48301 tattctacta cgtgcaaaga ttagaatgat aaaagtgaca atagataagt ctaaataaga
    48361 ttttttaata tataacaaat atgtattcat aagaaaaaaa gaaagtgagt gctaaaaaat
    48421 gctggaatta aacacgtcct tatcaaatag aacaatatta ataactggcg cagccggttt
    48481 tattggatca aatttggttc ttgagttatt acgtactcag tcatcaataa aaatcattgg
    48541 cattgacaat atgaatgatt actatgatgt ctctattaag aactatagat tatcagagat
    48601 agaaacggag gcaaagaacc atccaggatc tacttggaat tttatcaaag gttctattgc
    48661 tgataaagca acaattgatt tcatctttga taattataaa ccaagtatcg tggtgaattt
    48721 agcagctcag gcaggagtcc gttattcaat tactaatcca gatatgtata tcgaatctaa
    48781 cataatagga ttctataata ttcttgaagc ttgtcgtcat tcatatgata atggagaatc
    48841 tggtgtggaa catttagtgt atgcctcatc gtcttccgtt tatggtacta ataagaaaat
    48901 tccttattct acagaggata aagtagacaa tcaagtatcg ttgtatgcag caactaagaa
    48961 aagtaatgaa tcaatggcac atgcatattc taaactttac aatattccgt ctacagggtt
    49021 acgtttcttt acagtatatg gtcctgctgg gcgtccagat atggcttatt ttggttttac
    49081 tgataaactt cgtgctggtg ataatatcca aatattcaat tatgggaatt gcaagcgtga
    49141 ctttacctat atagatgata ttgttgaagg agtaaagagg gttatgcagt gcgctccaga
    49201 gaaaattgat ggggaagatg ggctaccaat cccaccatat catatttata atattggtaa
    49261 caatacgccg gaaaacctac tagattttgt agatattcta caacaagagc taattgcagc
    49321 aggggtgcta ccagaagatt acgactttga atctcatacc gaactagttc caatgcaacc
    49381 aggagatgtg ccagttactt atgcagatac tagtgcgtta gaacgagatt ttgaatttaa
    49441 accaagtaca agtttgcgtg acgggcttcg taaatttgcg cagtggtata agtcttttta
    49501 tgaagtataa ttgtattttt ttacttataa aagtttatag aaacacctca gacactacaa
    49561 atctgaggtg ttatttttta atctcgttga aataaatctc tggtatatac tttttctttt
    49621 acatcatcaa gattactatc gtaacgatta gcaataatac tgtgactgat atttttaaaa
    49681 tcatctaaat tatttattac ttttgaacca aaaaatgtag tgttattttc aagtgttggt
    49741 tcataaatta caatagttgc cccctttgct ttaattcgct tcataactcc ttgaatagat
    49801 gactgacgga agttgtctga attactcttc attgtaagac ggtatacacc tatgactacc
    49861 tctttttctt tttctgcatt ccacgaactg ttagcctcat acgtgccagc aagttctaac
    49921 actcgatctg ctataaagtc ttttcttgta cgattactat cgacaattgc acttatcata
    49981 ttctgaggaa catcgttata gttagtgaga agttgttttg tatctttcgg taaacaatag
    50041 cctccatatc caaaagatgg attattataa tgtgtgccaa ttcttggatc taagcaaacc
    50101 ccgtgaatga tttcttgtgt atttagtcct ttcatttctg cataagtatc cagctcattg
    50161 aagtaagata ctcgaagtgc aaggtaagta ttagcgaata atttaactgc ttcagcttct
    50221 gtgaatccca tgaaaagagt ttcgatatct tttttgattg ctccttcttg gagtaaatct
    50281 gcaaaagtgt gagaggcttc tcgtaaagtt ttgtcagttt ggtccgtgcc gacaataatt
    50341 cgcgaaggat atagattgtc atataatgcc ttagattctc tgagaaattc tgggctgaat
    50401 agaatatttt tagtattgta ttttttacga atactttcgg tatagcctac gggtaccgtc
    50461 gacttgatga ccattattgc ctttggattg acttctaaca ccaatttgat tactgactct
    50521 acagcagaag tatcaaaata attttgttta ctatcataat ttgttggagc agcaatgaca
    50581 acaaaatcgg cttctctata ggcggctgca ccatcagtcg ttgcaattaa attaagattt
    50641 ttttcagcta gatatttttc aatgtaatcg tcttgtattg gagatttctt attgttaatt
    50701 tgttttactt tttcaggaag aatgtctact gctgttacct gattgtgctg ggcaagaaga
    50761 gtagcaatgg aaagacctac gtaaccagta ccggctacag caatattctt cgactgatgt
    50821 tttgttctgt ttgatttatt tgattcattt ataaatagat ctgttggttc aaaatttaga
    50881 acttctgcta atgattctaa ttgttgtatt gacgggataa aatcgagaga ttctaatcga
    50941 ctaattaagg cacggttgat accagtagct actgcaagtt gttgttgtgt cattttcaga
    51001 gattttctag aatcaataat gatttgagct aaacgttttt gagataactt tttcatgatg
    51061 cactcctttt tttgttgcta ataataacaa acaattttt
//
LOCUS       DADGKS010000016        45748 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.016, whole genome shotgun sequence.
ACCESSION   DADGKS010000016 DADGKS010000000
VERSION     DADGKS010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 45748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45748
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.016"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..1008)
                     /locus_tag="JXV47_000981"
     CDS             complement(<1..1008)
                     /locus_tag="JXV47_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAX1487040.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(1188..1532)
                     /locus_tag="JXV47_000982"
     CDS             complement(1188..1532)
                     /locus_tag="JXV47_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAX1487041.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(1525..1959)
                     /locus_tag="JXV47_000983"
     CDS             complement(1525..1959)
                     /locus_tag="JXV47_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HAX1487042.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            2097..2834
                     /locus_tag="JXV47_000984"
     CDS             2097..2834
                     /locus_tag="JXV47_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1487043.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            2827..4038
                     /locus_tag="JXV47_000985"
     CDS             2827..4038
                     /locus_tag="JXV47_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1487044.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            4245..5024
                     /locus_tag="JXV47_000986"
     CDS             4245..5024
                     /locus_tag="JXV47_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HAX1487045.1"
                     /translation="MEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAAL
                     SREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLKT
                     MLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHGD
                     VNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDEM
                     LEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            5094..5756
                     /gene="trmB"
                     /locus_tag="JXV47_000987"
     CDS             5094..5756
                     /gene="trmB"
                     /locus_tag="JXV47_000987"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HAX1487046.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(5854..7608)
                     /gene="ade"
                     /locus_tag="JXV47_000988"
     CDS             complement(5854..7608)
                     /gene="ade"
                     /locus_tag="JXV47_000988"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HAX1487047.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNNQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            7740..8669
                     /gene="cpaF"
                     /locus_tag="JXV47_000989"
     CDS             7740..8669
                     /gene="cpaF"
                     /locus_tag="JXV47_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component"
                     /protein_id="HAX1487048.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            8626..9675
                     /locus_tag="JXV47_000990"
     CDS             8626..9675
                     /locus_tag="JXV47_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HAX1487049.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            9672..9950
                     /locus_tag="JXV47_000991"
     CDS             9672..9950
                     /locus_tag="JXV47_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HAX1487050.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            9925..10395
                     /locus_tag="JXV47_000992"
     CDS             9925..10395
                     /locus_tag="JXV47_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HAX1487051.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            10412..10714
                     /locus_tag="JXV47_000993"
     CDS             10412..10714
                     /locus_tag="JXV47_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487052.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            10731..11102
                     /locus_tag="JXV47_000994"
     CDS             10731..11102
                     /locus_tag="JXV47_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HAX1487053.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            11074..11433
                     /locus_tag="JXV47_000995"
     CDS             11074..11433
                     /locus_tag="JXV47_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487054.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            11605..12612
                     /locus_tag="JXV47_000996"
     CDS             11605..12612
                     /locus_tag="JXV47_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAX1487055.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            12637..13821
                     /locus_tag="JXV47_000997"
     CDS             12637..13821
                     /locus_tag="JXV47_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HAX1487056.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(14258..15841)
                     /locus_tag="JXV47_000998"
     CDS             complement(14258..15841)
                     /locus_tag="JXV47_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAX1487057.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(16419..16562)
                     /locus_tag="JXV47_000999"
     CDS             complement(16419..16562)
                     /locus_tag="JXV47_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HAX1487058.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(16785..17264)
                     /locus_tag="JXV47_001000"
     CDS             complement(16785..17264)
                     /locus_tag="JXV47_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAX1487059.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(17337..17621)
                     /locus_tag="JXV47_001001"
     CDS             complement(17337..17621)
                     /locus_tag="JXV47_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487060.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(17699..17893)
                     /gene="ssrS"
                     /locus_tag="JXV47_001002"
     ncRNA           complement(17699..17893)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="JXV47_001002"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(17965..19251)
                     /locus_tag="JXV47_001003"
     CDS             complement(17965..19251)
                     /locus_tag="JXV47_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HAX1487061.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            19389..20060
                     /locus_tag="JXV47_001004"
     CDS             19389..20060
                     /locus_tag="JXV47_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HAX1487062.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            20026..20514
                     /locus_tag="JXV47_001005"
     CDS             20026..20514
                     /locus_tag="JXV47_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HAX1487063.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            20527..21474
                     /gene="prmA"
                     /locus_tag="JXV47_001006"
     CDS             20527..21474
                     /gene="prmA"
                     /locus_tag="JXV47_001006"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HAX1487064.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            21475..22239
                     /locus_tag="JXV47_001007"
     CDS             21475..22239
                     /locus_tag="JXV47_001007"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HAX1487065.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            22472..24685
                     /locus_tag="JXV47_001008"
     CDS             22472..24685
                     /locus_tag="JXV47_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HAX1487066.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            24696..25142
                     /locus_tag="JXV47_001009"
     CDS             24696..25142
                     /locus_tag="JXV47_001009"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HAX1487067.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            25313..26572
                     /locus_tag="JXV47_001010"
     CDS             25313..26572
                     /locus_tag="JXV47_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HAX1487068.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(26661..27608)
                     /locus_tag="JXV47_001011"
     CDS             complement(26661..27608)
                     /locus_tag="JXV47_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAX1487069.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            28002..29294
                     /locus_tag="JXV47_001012"
     CDS             28002..29294
                     /locus_tag="JXV47_001012"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HAX1487070.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            29309..31078
                     /gene="aspS"
                     /locus_tag="JXV47_001013"
     CDS             29309..31078
                     /gene="aspS"
                     /locus_tag="JXV47_001013"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HAX1487071.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            31187..32062
                     /locus_tag="JXV47_001014"
     CDS             31187..32062
                     /locus_tag="JXV47_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAX1487072.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            32328..34211
                     /locus_tag="JXV47_001015"
     CDS             32328..34211
                     /locus_tag="JXV47_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAX1487073.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(34286..34570)
                     /locus_tag="JXV47_001016"
     CDS             complement(34286..34570)
                     /locus_tag="JXV47_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAX1487074.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(34560..35294)
                     /locus_tag="JXV47_001017"
     CDS             complement(34560..35294)
                     /locus_tag="JXV47_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HAX1487075.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            35423..36046
                     /locus_tag="JXV47_001018"
     CDS             35423..36046
                     /locus_tag="JXV47_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HAX1487076.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            36238..37359
                     /locus_tag="JXV47_001019"
     CDS             36238..37359
                     /locus_tag="JXV47_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HAX1487077.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            37366..40494
                     /locus_tag="JXV47_001020"
     CDS             37366..40494
                     /locus_tag="JXV47_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HAX1487078.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            40513..43707
                     /locus_tag="JXV47_001021"
     CDS             40513..43707
                     /locus_tag="JXV47_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAX1487079.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(43853..44560)
                     /locus_tag="JXV47_001022"
     CDS             complement(43853..44560)
                     /locus_tag="JXV47_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAX1487080.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            45325..45723
                     /gene="spxA"
                     /locus_tag="JXV47_001023"
     CDS             45325..45723
                     /gene="spxA"
                     /locus_tag="JXV47_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HAX1487081.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT        14730 a         8081 c         9559 g        13378 t
ORIGIN      
        1 ttttgatgaa tcagttgttt cttcagttga agattctttt gttgaatcag ttgattttgt
       61 gtcagaactc tttgttgaag ctgtagtttc acttgagtct ttcgtacttg atgaagttgt
      121 tgtgaatgca ctcaacacat tttcaaaggc atcatctttg atttttacat ttgcatcttt
      181 taattcttca ccgattactt tagttgtgaa tgcattgtca cttagtttag tttcagtagc
      241 gatatctttt agttgatctt tgtatttatc catgtcattg cctttatttt ggtttttcac
      301 cattttgaca acgtagtatt ctgtcgcata agaagtagga tttgttgtag taataacatc
      361 ggagatctca ccgtctttca atttgaaagc tgcttctttt acttctgcag gaatagttgt
      421 tgtcgttgag tcgaatttaa ctttaccgcc atcttctttt gtctctgtat cagttgattt
      481 gtctttggct aatttagaga aatcatctcc atcatccgct gattttttca catcttttgc
      541 ttcatcttca cttgataatt tgatgatttg tgcttctact tctggatgga aagatttcca
      601 agcagttttc aaatcgtcat ctgtaatatc tacgtgagct ttcaagccag cttcaaaagc
      661 taaattgtta cgaatatatt ctttataagt atctttcgta tatccagcag cttctaattg
      721 tgattcaaaa gtatcaccta atgatttcgc ttgtttgtcg tattctgcat ccacttgctt
      781 atcggttact ttatcgccat atttgttatt gaatacttta taaatgatca tccgttgtac
      841 taaggattgg ttcgatgatt caagttttgc ttcatcatag aaatcagata cagtgatcgt
      901 tccgcctttc atcgttgcga tatctttatt agtatcgcct gaacaagctg ctagagttaa
      961 aacagccaac gcactagtag ctgccaaaat aattgatttt tttttcatta aaatttgcac
     1021 tcctgtaatt agttattatt tttatatatt aactatacca tatcccattt cctttaaaaa
     1081 cgttgtcgtg gtagtttcaa acaaaattca aaatttcatc acattcctag gaaatacgca
     1141 aacttttctc acttatatag ttaaatctgt tgagaaaata atcattatta tatttgttca
     1201 ggatactctg gcagatcagc ttttagtttt tctacttgtt cattgatttg tgtgatacgt
     1261 ggttcggctt ggaatttaaa atcttcgata tcttttttga ttgcttcttg gaaagcagga
     1321 atcacagatt cagctgtttc ttttgtttcg atcaatgcgc ttttaaaatg attcaggctg
     1381 ttatttaaat catttgtcag agttgttgct tcttccaatt cttcgatcag tttctttctt
     1441 gtttcattcc cgctcctggg cgccaataac agacctccga cagtgccagc agcagctcca
     1501 aataacagtc ctttgaaaaa gtttttaatc atcgcaggac acctgcttta cgattgtttc
     1561 ttgaatagct tttagttctt ccgatccata actatcttga tgattgacaa agtgaataga
     1621 aaaatcatcc tctttgctgt agcgagggac taaatggata tgtgaatgaa aaacagattg
     1681 ataggctagt tcacggttgt tattcaagat attaagacct ttcatttctg gaaaagcttt
     1741 ttccaatgct tgagcaatct taggcacacg cgaaaaaacc tctcctgcaa gttcgggatc
     1801 atattcaaaa atatctgcta catgacgttt aggcacaact aatgtgtgtc ctttcgttgc
     1861 ttgagagatg tctaaaaaag catagacctt gtcgtcttca tatattttat agcttgggat
     1921 ttcttgattg atgattttgc aaaaaataca gttttccata taaaacatcc tttctataaa
     1981 gaataaatac ttcagcttaa ctttaccata agttaaagct attgtaagga aaaaaacaaa
     2041 ataccgtcat tttcttcgtg gtataataaa taaaaataaa tggcggagga aaaagaatga
     2101 gtttaattat cgatcatgtc acaggggggt acggacatct ccctgtgtta aaagatatca
     2161 gtttcgatgt acagcctgga gagatagtag ggttgattgg actgaacgga gcagggaaaa
     2221 gtacgaccat caagcacatt atcggtctgc tggaagcttc aaaaggaacg atagaaatca
     2281 atcatctatc cttaaagaaa aatacggaag aatatcgcaa acaaattggg tatattccag
     2341 agactccttc tttatatgaa gaattgacat tgagagaaca tatcgaagtc actgcgatgg
     2401 cctacgatat acctatggat atagcaatga aaagagcaga aaagttgttg gagacttttc
     2461 ggttatctaa tcgtcttgac tggttcccag ctaatttttc aaagggaatg aaacagaaag
     2521 tgatgatctt atgcgccttt ttgatcgagc cttctttata tatcatcgac gaaccatttt
     2581 taggcttgga tccactagct atcaatgcat tgcttgaatt gatggtagaa atgaaaaaag
     2641 aaggagccgg tattttgatg tctacgcata ttttagctac tgcagaaaaa tattgtgatc
     2701 gttttgtggt cttacataac ggagagatac gagcagacgg ttctcttgag atgttgagaa
     2761 aagaatttca gctgccggat tcttctttgg acgaaatcta tattgcttta acaaaggagc
     2821 aggcacatga gtagtttttt tcaaaaacgt ttagcaagac atcaaaagaa aatgatgaaa
     2881 tatatgcgtt atgtattgaa cgatcatttt gttttagttt gtcttttctt gattggcggt
     2941 gtgggattat attattctaa ttggttgaaa accctgcagc caccgtttgc aattggaggg
     3001 ctcataatct ctgtattttg gatgctctgt ttattcgtgg gtaagatggc tacttttgca
     3061 gaggcagcag atattgtttt tttacttcct aaagaaaaag aaatgcaaac ctatttggaa
     3121 cgagcttttc gctattcttg catttttccg ttgatctttt tgatattggc atgcggattg
     3181 gccatgccat tagtggtggt tagtacggag caatcctttt cgatgttttt cgtctatctg
     3241 atcatattat ggagtttgaa attcagtcat ctgcaaatca agagagcaga attgtttcga
     3301 ctagatcaac aagttattcg ttattggaaa ttaggctggt ttttttcttc tctgatcttt
     3361 ttgtttctat cattttattg gctaatatgg gcaggaatag caggtgcatt agtacaggca
     3421 agtctatatt actggttttt gtggaagcaa caagaaaaag gattggattg ggagaaaatg
     3481 gtgcatgtag aagaacatag gttgcatcag atctatcaat ttatcaattt attcacagat
     3541 gttcctgaaa ttacggcaaa gatcaaaaga agacgctatt tggatcctat attgactcat
     3601 attaaaagag aatcaaaaaa cacttatctt tacttgtttg caagaagatt ggcaagaggt
     3661 tctgatttta gtggtcttta tttccgatta gtaattatag gtgggttatt gattgccgga
     3721 gtagtcgact tttattttag tctgattatc ggtttcttat ttttatattt gatcggtttc
     3781 caactgttac ctttagcgaa ccagttccgc tatatggttc tcgttcagct ttatccaatc
     3841 cataagaatc agaagaagca ggcgattcag tatctactca catgggtatt aattatcgcg
     3901 tcggttattt ttggtttgat tgctgcagtc gtattagatg ggcagcagcg atgggttccg
     3961 ctagcggctt atttgattgt tactatgctc tttgttaaac tatatgtacc aactcgtttg
     4021 aagaagatgt cagactgaaa acaaagctgt gtagggtaaa aatgagaatg aaaaatagag
     4081 cgttgacagt aagaatgctg ttcgttctat tttttttgag aaaagctggt tttttgaatg
     4141 gcaattaaat gaaaaagaac gtatatgtgc ttgacgtgta gtgttcaggc gactagaata
     4201 ataagtactg caaaacaaag agtaagagga cgggagaatg catgatggag tttcagttag
     4261 accaagagtg gcggttacgt cccatcaaag gcgacacagg aaaaacatac ataggcatgc
     4321 gtgatgagga caaagtcttt attaaacgaa acacgactcc gatgttggct gctctttcaa
     4381 gggaaggaat tacaccaaaa cttgtttgga caaaacgaac ggggaatggc gatactttga
     4441 cagcacaaga gtggctggaa ggtcgcttgc tgactcctaa tgagattggt caaagaaacg
     4501 acgtgattga tgttttgtac catttacatc attcaaattc tcttaaaacc atgctgaccc
     4561 gtatcggtgg tcgtgtcatg acgccggaga agatgctgca aaaatatgaa aaagaattac
     4621 cggaagaact ccagaaaaat caatttctgc aaattgtcca tcgttttctt cgtgagcaga
     4681 tcccgtcaat agataaggaa aacttatcag tagtacacgg agatgtaaac catcgtaatt
     4741 ggttagtatg taaaaattat ttatatctag tcgattggga ttcaatcatg tttgcagacc
     4801 ctgcggtgga tattgcaacg attttaggaa attatgtgcc actgtctagc tggaatcagt
     4861 ggctgatcag ttatggcata cgcccgactg acgaaatgct tgaaaaattt cattggtatg
     4921 cggccatgaa tttgctccaa gaaatcacca gatattgcaa acgtgaagat catcgacgga
     4981 tgaacgaaga aattttacaa ttaaaacgaa ttttcagtgg ctgaggtttg gcccaaactc
     5041 tgcggagatt tggccagacc tttttaatta gaggaaagga atggagataa ataatgcgtg
     5101 tccgaaatcg tccgggagca gcggaaatgt tagcggctca cccgaatttt gtaattagtg
     5161 atccaacatt gtggaaggga aaatggaatg aattgtttga aaacgatcat ccaatccaca
     5221 ttgagattgg tatggggaaa ggccagttca tcactggaat ggcaaaagcc catcctgaaa
     5281 tcaattatat tggagtagaa atgcaggtca gtgttgtttc gattgcacta gacaagttga
     5341 tcgaacaacc gcttcctaac ctgaaacttc tacatgtgga tggatcagcg ttgacagagt
     5401 atttcgctga cagcgaagta gatcaaatct atctgaattt ttccgatcca tggccaaaaa
     5461 aacgtcatga aaaacggcga ttgacatata agacttttct tgctgtagat gaacagattc
     5521 ttcgtccaaa tggagaaatc catttcaaaa cagataatca aggattgttt gagtattctc
     5581 tggcaagttt ttctcaatat ggcatgatcc tcaaacaggt atggttagat ttacatcaaa
     5641 gtcaatttga aggcaatatt atgacggagt atgaagaaaa attttcttca aaaggtcaac
     5701 gtatttatcg agtagaagct caatttcaag ataagaccaa aaagaaaagt ctgtgaaact
     5761 aactttctgc tttcataaaa acattaatat ccataaataa atcccagaaa atgaacatta
     5821 cagatgtaat gtattttctg ggatttattt gatttaaaat gtatttattt catcggtttt
     5881 tccacaaggt ggaatcaatt ggaagcgaga aaatgaaaat aatcctttgt cggtgatctt
     5941 caattcgggt atgacagata atgttaagaa agaaagtgtc aaaaaaggat caaaggtttt
     6001 agctgctcct agttgatgtg ctttagttat taattcattc aactgttcat agacgatcga
     6061 aaaaggttcc tgtgtcatga ttccgcctat aggaagagaa acacaagcta tttcctgctg
     6121 attgttgaca acggtcatcc cgccaccttt ttgaatcaaa agattagcag catacagcat
     6181 atcctcgtcg tttgtcccaa cgacaactag attatgcgag tcatgggcaa tcgttgtcgc
     6241 tatcgctcct tgtttcagct gaaatccttt cactatgcct aatccaatgt ttcccgtttg
     6301 atggtgacgc tcgatcaccg caatctttaa ttggtctttt tcgattgaag gaatgaatcg
     6361 ttcgccttgt cggtccactt tttctaccaa atctttagtc actagactat tcgggataat
     6421 ttcgatcaca tgggcttgtg aagaagaaag aagcagctct aacgaatgtg gatttaatgg
     6481 ttgagcgttt agttttggca gacaacacgt atatgaattt gaatgatcag caaataaatg
     6541 gtcttggagt tgcccagatt gaacaactaa tgttccctta tagaaaactt catgaattgg
     6601 cagcttggta agatcgtctg ttaagaagaa atcagcttga tacccagggg caatcgcacc
     6661 tagtgttttc aaatcaaaac attctgctgc attcaatgtt gccatctgaa tggcttgtaa
     6721 tggatcgatt ccaagtgcaa tagcttgacg gacgatatga tcgattgatc cttcttttac
     6781 taaatcattg atcagtttat catcggtgac aaagaagcat cttcttgaat tttcaggtgt
     6841 gatcgccggt agtagcgatg ccagatcttt tgcaacggtc ccttctcgaa ccattaaata
     6901 cataccaaga tccaaacgtt ctttagcttc ttttgcagtt gtagcttcat gatccgtccg
     6961 aatacctgct gcaggataaa catttaactc ttccatgccg ataccagctg catgcccgtc
     7021 aatttttttc ttatgctggt gcatcaattg gatcttttct aggatgtctg tttcattatt
     7081 tgctactgct tgatagttca tgacttcagc taagcctaaa acttcgggtt tttgtaaaaa
     7141 aggggctaat ttttttgcat ttaaatttgc accattggtc tcaaaagggg ttacaggtac
     7201 acaagaaggt agcataaaaa agatattcat gagtgtttgt cttgcatctt ctatcataaa
     7261 ctcaagacct gtactcccag caatgtttcc tatttcatgg ggatctgtca ctacagtagt
     7321 aactccatga agcaaggata cttttgaaaa ttcgcttggt gataaaagtg agctttcgat
     7381 atgcacatgg ccatcgatga atcctggcac tagatattgc ccattagcat tatgtacgct
     7441 ttttccttcg tattcaccga ttcctacgat cattccttcg cagattgcta catctttttc
     7501 catgatttct ttcgtaaaga cgttgacgat cttagcatgc ttgatcacta ggtcagcagg
     7561 ctttttttta cttgctactt cgatatattt ccttaatgtt gtttccaatg gagtgcctcc
     7621 caagataaat ttttataagt ataacataaa ttcggttttt gccaatattt ttttgtaaat
     7681 tcattttatt tgaaacaaaa agatcaaaaa gacgtatgtt ttttgtggag gggagaataa
     7741 tggaaataaa acgattatcg gatcaaatga taagtgaaag ttttgccaaa catgcccaag
     7801 acgtatatat attgccagct tcagaagtat tttacatcta ttttcgctat ggaaaaaaac
     7861 gaacattctg gaagaaagtc tcttcggcag atggacagca actgatctca agatttaagt
     7921 atttgggaca gatggatatc ggagaaaaaa gaaaagctca gttaggtgca tttacttatt
     7981 ctttagaaaa acaggaagtt cgtctgcggt tgtcttctgt aggagattac cttcaacgag
     8041 agagtttagt gattcggcta ttatacggta cttttgaaac accccatcgt tgctttagtt
     8101 ctcgagattt tgcaactatt ttacagaaaa ccgtcagacg tggattatac cttttcagcg
     8161 gaccagtcgg atcaggcaag acttctctaa tgtatcggtt ggctttggaa gaaaaattgc
     8221 aagtgattac tatcgaagat cctgtagaga tagaagaacc gttttttctg cagctacaga
     8281 tcaatccgaa aatagcacag acttatgata cacttttgag actcgcatta cggcatcgtc
     8341 cagacttgct aatcattggc gagataagag atgaatcaac tgcacatgct gcggtaagag
     8401 cagcactaac agggcaccgg gtttttgcaa ccgtacatgc acgcaatctt gaaggtacat
     8461 tggtcagaat ccatgaactg acaaagaaaa aagaagagct atctgaatgt ttagctggtg
     8521 tcatttatca agaacttttg gaagatgcca atcaccatcc ttctgtttta tggagttatc
     8581 aatttatgga ggaagaatca gtaaaaaaat catgggagga aagttatgaa gaagctcagg
     8641 aaaatatttg gcagtcagaa ctattctaaa ggattaacaa gaagccagca aaaccagttt
     8701 gcacaaacca tgggagaact gcttttatct ggttttagtc tgcaagaatc cctttattta
     8761 ttactcacga tccgttcgtt tccacctgtt attttggcaa atatccaaca tcagctaaag
     8821 gaagggcaag cgtttagtga ggtactttcg caaataggat atggagcaga gcaactggta
     8881 cagatcgagt tagctgaacg tcatgggaat ctgccgacaa ctttgttgga aattgccaaa
     8941 cagtttcggc ttgttgaagg atttcgcaat gatttgaaaa agctgcttgc atatccgatg
     9001 ctattgctca cctttttgct aggtatcttg tttagtatgc ggttgttcgt tttgcctcag
     9061 cttattggtt caggaatggt catgcaagag cattggggta ttcagctgat acaagtcttt
     9121 cattggtatg ttctactatt catcctagcg gttactctat tggctttact agtaaggtat
     9181 cgtctgatga agttgtctcc tgttgatcag agtgaatgga taagcagaca attattgatt
     9241 ggaccgatat attccttgta tcaatcggct tatttgtcac tagagattgg aaagcttttt
     9301 catgaaggtt tcgaattaag gcaaatcata gtctgcttaa aggaaacgaa acaagaaagt
     9361 ctgattcagc atcttgcctc taagttgatt caaggattgg aggcaggtat gtcattggct
     9421 gagcagttcc agaattatcg ttttctatca gaagaattca gtaaaattgt tttacaggga
     9481 gaggcaaagg gaagtttagg taaagaactg attttttaca gcgaatggac aagaaaacag
     9541 cttttcaaac gtcttcatca ctggatgcat tttattcagc caatcatttt tttgggcgta
     9601 gcggctttga ttttattagt ttatgccgct gttttattac ctgtttacgg aagcatagag
     9661 gaggttttgc catgaaaaag agaaaaatat cttattatag cggttttaca ttgatcgaaa
     9721 tgctaatcgt cttactgatc atcagtgtat tagtgttgtt gttcgtccct aatttgtcgc
     9781 gttataggaa tcatgtagac caagaaagtc gtgaagcgat catccagttg gtagacacac
     9841 aaaaagagct ctatgcgctt caaaataatg gaagagttcc tactgtggag gaattgttga
     9901 atgaaggcta tatcaaacga gaacatgcag aaatctatca gcggccttga aggtaaggtt
     9961 ttagcatcag gatatacgtt gtttgaatca ctcttactga ttttattact tacaacgatc
    10021 ctttcttttc cagttctcgc attttctgca tggaagaatg aattggcagt ctatcaattt
    10081 ttcggccaat ttgaaaaacg aatctattct acgcaaaaaa tcgctattgt gaatcagatc
    10141 caaacaggct tttattggaa tagtgaagag aatcaaatca tttttcatgt tccgaatcca
    10201 gataaaataa attgggaagt attagatatt cctgatgaga ttaccttgaa acgccatgct
    10261 tctattactt ttgctgctag aaccgggaat gaaagttcac taaaagctta tcaattttat
    10321 tgggaagaaa aagagcggac gattacgtat caattccaga tagggagtgg tcgctataca
    10381 aaaagaattg aataaaacag gatttgtttt gttggagtcc cttacagcgc ttatgatcgc
    10441 ttctgtctgt gtctacttag tgagctttgg ccagctgttt ttgcttcagg cagaaaagaa
    10501 aagtggggag gaactgctat ttattcgaat gatttatgaa gatatcaaga cgcagcggat
    10561 gtatcacaaa agaccagagc gaagggaaga aatgatccca tacgatatcc aaattgtcga
    10621 taataatgga gtaatcgaaa aagtgtttgt caatatggag aaagaagcga tcagtattga
    10681 aaaaacaagt aattccagca tttacgctga ttgaatgtct aattggactg atgatattga
    10741 gcagtctatt gctcacattc aatcttttga ttcagcaaac catccaagta agtgaatttt
    10801 tgcagcgtaa agatcaaaaa gagtggctaa tatttttagc acaattagaa gaagaactca
    10861 agagcagtca caatgtctct gtgaaaaatc agcaactgca ctacacgatc gaggataaac
    10921 agtatatcat cgaaagatat caggcaatga tacgtaaaag aagaacttcc ggcggacatc
    10981 aacctatgtt aacaagtatc actgagcttc aattattgga aaaagaacac acaatttctt
    11041 tttatgtaca ctttgaaaat ggagaagatg gatatgccat atggacaaaa aacgatcagt
    11101 agaaaatgtt ataagggctc tattttattt tctgtcttgc ttttatttct tttatgtacg
    11161 tttttattga tggcagcatt agaaagctac cgtttgtcaa tggatcttaa tatacgaatc
    11221 aaaaattatt atatagcaaa aataatgaag cagatggctt tatcggaaca gtctacgctt
    11281 gccgaaagtt cggaaggagt tttttactac acaactggat ctgtaacata tcagtgggta
    11341 caacagtccc tattcttaga ggtggaagtc tcaccgttta tctttcggtt cacagaagaa
    11401 gtaaaaaatg atacagatac tagtacagaa tgatggaatg ttcgtgaaaa cgccctcttt
    11461 tctgttataa cactgttttt aataaaaaaa tgtttgccgt ttcacaaata aaaaacagtg
    11521 aaaacgattg aaattttgtc aattgttcga tagaattaaa caggtgaaaa aattgttata
    11581 atatatctag aaatgaggtg caccatgtta ccagaaaaaa tggaacaagg gtttaatcaa
    11641 aacctggaag ctattcagct tttacagaat gcattgggaa cttccttttt agaagcctat
    11701 gtcgaaaatg cagaaaattt aatagatgat tatcaagtac gtgtggtgga tggagtgccg
    11761 acaaaagaga caacgcaacg gatcacagct ctttatgaag agttgaagaa actttctttc
    11821 gagccagaag aatggcgcag actgtctcaa ttacttttat tgaagggcag ccagacagaa
    11881 catttgcagg cgaaccatca actcactcct gatagtatcg gttttttatt tgtttttctt
    11941 attgaacaac tatacacaaa taaaaaagca ccggttaaga ttctggatat tgcggcagga
    12001 atgggcaact tgttattaac agttctttta aacctatcga atgcggggta ccaaacagaa
    12061 ggaattggtg tggatattga tgatacattg ttggctgtcg cagcttctac aagtgatttg
    12121 acacaagcaa atgttcaata ctttcatcaa gacgggttgc aggaattatt aatagatcct
    12181 gtcgattttg caatcagcga tttgccaatc ggttattatc cgaatgacga aaaagcaaaa
    12241 gagtttttaa caagtaccga agaaggccat agttatgcac atcatttatt gctagagcaa
    12301 tcaatgaaat atgtgaagcc ggatggtttt ggtttgtttt tgatgccgag tggattttta
    12361 gaaacggatc aaagtgaaga aatcaaaaaa tggtttaaag aagaaggtta tcttcaagga
    12421 atgattcaat tgccagatga attgttccgt aataaacaat cgcaaaaaag tattttgatc
    12481 ttacagaaaa aaggaccaca agcacaacaa gtaaaagaag tcttgcttgt gaaacttgct
    12541 tcattaaaag aaccagagaa ggtgacggaa tttttcaacg agtttaaaaa ctggaaatca
    12601 tctgctctgt aatcattcaa cgagaaggag agtcatatgt ctaaaacaat tgcaatcaat
    12661 gctgggagtt caagtttgaa atggcaatta tatcaaatgc cagaagaaac cgtagttgcg
    12721 aaagggatcg tcgaacgtat cggtttacaa gattctattt ttaccatcaa gtacggcgat
    12781 aatcaaaaat tcgaacaaat catggatatc gaaaaccacg aagtagcagt aaaaatgctg
    12841 ttagatcagt tgattgaact gcaaatttta agctcttatg atgaaatcac cggagtaggg
    12901 caccgtgttg ttcacggagg agaaacttat ggggattcag tagtgatcga tgagaaagta
    12961 atggaccgca ttgctgaatt agcagaattt gctcctttgc ataatcctgc aaacttaatg
    13021 gggatcaaag cgtttaaaaa gattttacct gacattttga gtgtggctgt attcgataca
    13081 tctttccact caacaatgcc aaagcaaaat tatttatata gcttaccggt gtcttattat
    13141 gaagatttca aagtaagaaa atatggcttc catggcacaa gtcatcgtta tgtgtcggaa
    13201 cgtgcggcaa aattattgaa caaaccgatc gaagaactaa aaatcatcac ttgccactta
    13261 ggaaatggtg tatcgatcac agcagtcgat ggaggtaaat ccatggatac ttctatggga
    13321 ttcacaccat tagctggggt gacaatgggt acacgttcag gtgatatcga tccagctgtt
    13381 ctcccatatt taatggaaaa attagagatt gatattgatg aaatgatcaa tgttttgaac
    13441 aagaaatctg gtctgctagg cctaacagga ttgtctagtg atatgcgtga tcttgaaaag
    13501 aactatgaaa aagaacatat tcgtttagct tatgacattt tcgtggaccg catccgaaaa
    13561 tacatcggcg gttatgtgac aacgatgaat ggtgttgatg caattgtctt tactgctggt
    13621 atcggcgaga atgacggaca tgtacgtagt gaaatcatca aaggtatgtc ttggtttggt
    13681 tgtgaaatcg atccagcgtt gaatgaattg cgtggtgaag aagtagatat ctctacaaaa
    13741 gaatcaaaag taagagtatt agtgatccca acagatgagg aactaatgat tgcccgtgat
    13801 gtggagcgtc tgcgcggcta agccaaagca ttcgttagga taaaagatga aacgcatgca
    13861 agagggaatt cttgcatgtg ttttttttgc ggagaagacc gcaaaatggt aatttaactt
    13921 caatttccct tcttttttac aggatcttct tagggaattt tgcttggaaa agtggtcaaa
    13981 agggaaaaga ctggcatttt atttattgat tttcaggaaa atcccaatat tttattttca
    14041 ttcatcttta taagggacat tacatatgta aaaagaaaaa acatttttag atcagcctcg
    14101 tgggctgtcg actttattct tcgctttatg tttagctaga aaaccgatcc gaaacattca
    14161 ttgatcgaat aataaaaact tgattttcca cctgtacttt gcctgaatcg tgaaagcaca
    14221 ggtatgaaaa tcaagttttt tgttgcgaaa aaacgtccta gtcaatcagt tggccgagcg
    14281 gctggcggct gatctgctcc tgatcaataa cgagtgcttc ttggaagtgt tgctgcaaaa
    14341 agtagcggtc atggctgact gctaggagcg ttccttgata gtcttgcagc atttcttcaa
    14401 tttcttctcg agcatagctg tcgaggtgat tggttggttc atccaaaatc aggacgttga
    14461 ttttttctaa aaagagtttc agcaacgcca aacggatttt ttcaccaccg gataaatctt
    14521 tgatccgttt acccacatcg ctttgataaa agccactttt ggctaattgc cgtcgagcga
    14581 cttcttcgtt tccagtcaat gtgatggcgt aagccagcaa acggctatcg ggatcggcaa
    14641 actgcagctg ctgcggcaaa taaccgattt gcaagctact acctaatttg atggtgccac
    14701 cgtaaggctt ttcctcaccg agtaataatt tgagtaaggt tgattttcct gcaccattgt
    14761 cgccgatgat ggctaaatga tctccacgat agactgcaaa actgctgtct ttgaatagta
    14821 cttgatcagc gtactgctgg tgcaagtttt gaatgatgaa aacttctttg ccagattttc
    14881 caccattaga caagctttgc agccgatttt tcgggggagg tggcggtttg acgagtgtca
    14941 gtttcgccag gcggcgttcc agttctttgg cttttttgaa gaaggactca ttgtctcctt
    15001 catgtgccca ctgacgaaaa cgacgaatca tgactttcaa ccgctggact tctttttgct
    15061 gcagttcgta attttttgtc agctcagcca agcgagcttc tttcaagact cgaaaacggc
    15121 tgtagtttcc gggatactca atcaatgcac cttcttccag ttcccatgtt tttgtggtga
    15181 cttgatcgag aaattgccga tcatgagaaa cgaccagaac cgattttttt gtattctgta
    15241 aatagttttc caaccagcga atactgttaa gatctaaatg attggtcggt tcatcgagta
    15301 aaagtaaatc ggcatcggct gctaaaattt tggctaaagc gactttaact cgttcgcctc
    15361 cgctaagttc tgttaaccgt gcttcctgac ggtgtggaat ccctaagcct tgcaagatcg
    15421 ctgcaatccg gtcttctaat acgtaaccgc ctagttcttc aaagcgatgc tgcagctcac
    15481 cgtaacgggc cagacacttc tctaagtttg tatctggttc tgtcatcaat gcttcgtagc
    15541 gactcatttg ctgtttgagg tcctgtatct cagcggcaga atggagcaag tagtggttga
    15601 cggtcgcttc ggaaactgta agttcttgtt cgaccgtccc gatctttaag ccttttttgc
    15661 gactgataac accgctgtcg acaccttctc tgccggtcaa gatttgtaaa aaggttgatt
    15721 tgccagttcc gttgataccg actaaggcaa ttttttcacc agcttcaatt tgacaggata
    15781 aatcctcaaa taatggattc ccgccgattg tttttttaat agaaattgct tgtatgatca
    15841 tgatctctct ccttgagacc actcaaaaag gccatggtta tccatggcct gtgttattta
    15901 aactcagatt atcatgagaa aaataccttg agatggccat tgattttacg tgaattcaac
    15961 tgttttggac aaacttgtcc cgtcaacagc aactgtaaaa ccaattgcat ggctaaatgc
    16021 gatatggtat cgttggtaat tttcattact tgttatttta gtcatgcgca tcatagtatt
    16081 ttccctcctt cgtgtagttg tcttttccag tgtacctgaa agtgtcagaa agttcaacta
    16141 gcgctgacat ttacttaata tttatcgatg tgtaattctg tcagagagct ttttttatct
    16201 gactgagggt aatgtctcgt ggaccacatc attgtattct gagctaaacc agcgttcagg
    16261 cgaaatcata tggtgtttga taaaaaactt tgtctacatg acttcctttt gccatttgct
    16321 taataccgtt gcattaaaca gctcttctct ttggaaatct caccaacatc gcgttcagga
    16381 gtatcgttgt ggttgcaatg gcaagcggta gcctttcatc aattcttgaa tgatttaccg
    16441 aatgtagcac ttgccttctc gcggtacccg aacccgaaat aaaattttag tttggcgata
    16501 aaatcggtat ccgccatcga tacttcatat tttttcgtat cagattcatc ggaaacttcc
    16561 acattgacga accaataagc tttggcatgc ttaggtcgtt ttaaaccaca ccagggcgac
    16621 taatcgccct ggtgttcact tttttttatt ttacttgaac tcattgactg ttttcccttt
    16681 attttaaaca ttataaagac cgatgagtgc ttgccgcgtc ttttgttttt atcacggttt
    16741 tttgtgcaaa aaaacctgcc gatagttggc aggtcgtcta cgtgttaagc tttggtgtgg
    16801 tctttagctg gcaattggtt ttctaaatca gttcggacaa caagcacatc gcaagctgcg
    16861 tttctaataa catattcaga aacagaacca ataaataaac gttctacagc attcaatcct
    16921 gtggctccta acataatcaa atctacttga ttatcttctg ggatttctct ggcaataatt
    16981 tgttttggtg agccatattc tacgacagag gttacattat tcaagccagc tttcttcgca
    17041 ttgctttcat aatctgccaa tgtttgcttt gccatttcag tagcttgttc tgcaagcatt
    17101 ccatcaaagg atgaaacggt ttggaaagaa cgtgtgtcaa tgacatgtgc taatagaagt
    17161 tctccgttat ttcggatagc tacattgacc gcctttttaa aagctaattc agcttcatca
    17221 gaaccatcta cggcaaccat gatttttttg tattgttgta acataagcat tcactcctca
    17281 agtcaatcgt attgtactct tttattgtag aacactttag ggaaaaagag aattatttac
    17341 tgctttggtt cagcaatttt ttttgcaaat cggatactga aggtggcaga aacaataatt
    17401 acgatcagta aaaagaccaa ggcaataaag cgttgattga aaaaagctgt taaaataccc
    17461 attacgccta aaacagcata tgcagctccg taaaattgta ggaatccttg atttttatca
    17521 tttttgttga tcaatacaaa aaagatatcc tgtttattaa ataaataata gctaacgaat
    17581 aataatacta aagtggcgat aatcattaaa atcctaatca tgaacaaatc ctccaaaata
    17641 agcaacaaat agaaaaagca atttgccaag agcaaattgc tttattcttt aaaagatggt
    17701 aatctccgtt aatgccgttg tttgtcctgt agtattgatc ccgcgaattc aagcaggtgg
    17761 gtcccatggt cgtagcttcg aactaccaaa tgataaggca tgttaccagc agtgacacaa
    17821 gacgggtccc aagatatcaa taaaaatgtt cggtcaacac acaaagagga caattcgaac
    17881 atcacagatt tcccacctct atagtagcat atgaatttaa aaagagcaat gagagagctc
    17941 gcagaaacag aaccgttttc ttgtctagtt ttttggagga tgctttttcc actcttttat
    18001 acggtaatac tgttgaccca gagcctgttc atatttccct gtatcttttg gctgataata
    18061 ctgagcattc ttcagtttat ctggtaaata ttgctgattg acccaagcct gatcaaaatg
    18121 atgaggatac tgataaccca cgccacggtt gagtgatttc gcacctttgt aatggctatc
    18181 tctcaaatga tcaggaacat ctccagcttt gccctctcga atatcagcaa gtgctgcatc
    18241 taatgccatg taggcagaat tggattttgg cgacaagcaa agatcgacga cgacgtctgc
    18301 tagtgggata cgtgcctcag gcaatcccaa tttttcagca gctaatacag cgttcactgt
    18361 acgagccgca gcagcaggat tacctaaacc tatatcttca taaccgataa ccatcagacg
    18421 ccggcaaata cttgccagat cacctgcctc aactaaacgg gcgagataat gaagtgcagc
    18481 atccacatca cttccacgaa tcgatttttg aaaagccgaa ataacgtcat aatgagcatc
    18541 tccatttttg tcatgggtaa gagcttttct ttggacacat tcttcaatga tcgacagtgt
    18601 aagatgaatc cttccttctt tatctgaagg agtcgatagt gtagccagtt ccagcccatt
    18661 caatgcactc cgcaaatcgc cgttcgttgc acgcgaaagg tgaagaagag catcttcgtc
    18721 taactggatt gcttgttgtc caaggccgcg ttctttatcc cttaaagcat gttcgactgc
    18781 caactggatg tcttgttctg ttaatggttt gacttcaaag atctgtgtac ggctgcggat
    18841 cgctggattg atggtaatat aaggattctc agtagtcgct ccgatcaaga tgattcggcc
    18901 actttctaaa tgaggaagca gaaaatcctg ttttgtttta tctaatcggt gtacttcatc
    18961 caataagagg atcactgtac cactcatttt tgcttcttcc gctacaactt gtagatcctt
    19021 ttttgaatct gtagcggcgt ttagcatgcg aaatgcataa ttagtagagc cggcgatcgc
    19081 acttgcgata ctcgtttttc cagtaccagg aggtccatat agaatcatgg aagagagcat
    19141 gcgagcatcg accatgcggc gtatgatttt tccttccccg actagatgct gctgaccaac
    19201 gacttcatcg atcgttcgag gtctcatgcg ataagccaat ggctgttgca taggattttc
    19261 ctccttcttg tttttacgtc ccttaattat atcatattta gcaagatgcc tagaaagaac
    19321 agccttctgt tgttttgttt tcatagctta tccaactaat attgtgtatg ataaagtagg
    19381 tgagaaaaat gacggataaa caaaagatag atgaattttt ttggaataaa acgacgccag
    19441 aagtggcacg ggatttattg gggatgtatt tggagcatga cacaccagaa ggaagattag
    19501 ctggatatat tgtagacgcg gaagcatacc taggtccaga agacgaggcc gcccatagct
    19561 atggtttaag aagaacaccg cgtgtgcggg caatgtatga aaaaccaggt acgatctacc
    19621 tttacacgat gcatactcat cggattttga acatcattac tcagccagaa gggattcctc
    19681 aaggagtaat gatacgtgca atcgaacccg ccgcaatgat tgatcaaatg agtaaaaatc
    19741 gtggcggaaa aactggtcca gatatcagca acggtccggg aaaattagtg gaagcattag
    19801 caattcctca agaactttat ggtcagtcta tagcagatag ttcgttacgc ttagtttttg
    19861 agaaaaaaaa gacaccaaaa aagatcaatg ctttgcctag aatcggtatc ccaaacaaag
    19921 gtgtatggac agaaaagccg ttgcgttttg ttgtgtcggg aaatccttat atctctttac
    19981 aaagaaaaaa ccaaatcgag aaagattggg gttggaggaa agaaaatgaa aaagaaggat
    20041 ctattaacat atttagatga aataattgaa aaacaagtga cagactatga tgtagcttta
    20101 gattgggata caaaaaatca tacgatcgag atcgttgttc gcttgtttgc agaaaataaa
    20161 gcacaatttg agattgatga tgcagaaggg atcgtttcgc aagaaccaat tatcgaattt
    20221 gaagacggcg tacttctttt taatcctcag aaatctgttt ttgatgaacg caattatcta
    20281 gcagtaatcc cttatgaagg aaaaaaaggg ttggcaaaat cagtagctga ttctttagtg
    20341 gaatatctaa atgaagtatt agctcaaggg caaagcgatt tgcttgattt tttggatgaa
    20401 gacgatgacg aagctgtatt cgagcttcac tgggataatc agcaactagc agaattagta
    20461 gaagtaaaac agcaaaatga agcagatact tatttaccgt acccaagtta ttaaggagtg
    20521 acagatatga aatggaatga agtaaaagta gaaactgaaa gtgaagcagt cgaagcagtt
    20581 gctaatattt tgatggaggc aggggcgagt ggtgtcgcga ttgaagattc tttagatgtt
    20641 gaacattttc agtcggatca atatggtgag attttagata aaaatgattt tacatcgctg
    20701 aaagaaggcg cactagtcat ggcttatttt ccggaaacga ctttcttacc ggaaatcttg
    20761 ccttttatca aagatcgtat cacacaatta cctgagtttg gtctagctat tggaaaaaat
    20821 aaagtaacag ttagtgaagt agaggaaagc aactgggcaa cagcctggaa gaaatactat
    20881 catccggtgc gtattacgcg aatgctgacg gttgcgccaa gctgggaaaa ctaccagaca
    20941 gaagatcctc tagaaaaaat tatcacacta gatcctggta tggcatttgg cacaggcact
    21001 catcccacga cttccttgac attgacagca ctagaaacag tcttgcgtgg tggtgaaaca
    21061 ttgctagatg tgggaactgg gtcgggcgtg ctaagtattg cagcaaaata tcttggtgca
    21121 aaagatgtct atgcctttga tttagacgaa gtagccgttc gttcggcgaa agaaaatatg
    21181 gatatgaatg aaatagccaa agatgtccat gtatcagcta acgatctttt gacaggaatc
    21241 gagattgaaa gtgatgtaat cgttgcgaac attttagcag atatcatctt attgatgatc
    21301 ccagatgctt ggcgtttact gaagcaaaca ggcacgctga tcgtttcagg aatcattgaa
    21361 gagaagaagc aaatggttct ggatgccatg ttagaacaag ggtttatcgt ggatcaaatt
    21421 ttccagcaaa aagactggta tgcaattatt ttgaaaaaac cagaggtgga atagatgcag
    21481 cggtattttt taaaagaatc atatgaatca aaagactatt ttgttttaga aggggaaaac
    21541 tatcaccaca ttgtacgggt tatgaggatg gaacccgagg atgaagtttt tttggcattc
    21601 aatgatcaaa tagccattgt tgcagaaatc acggagatta ctgaagaggc tgtttatctg
    21661 aaagaaatta aaaaagaaga aaatcaaaag gaactgccaa gttcgattac catagcgagt
    21721 ggctatccta aaggggaaaa gctggattgg atcgttcaga aatccactga attaggagcg
    21781 caagcttttc ttggtttccc ggcatcagcc tctgtcgtta aatgggatgc aaaaaaacgt
    21841 atgaaacgac aacaacggct tgaaaagatt gctcaagagg cagcggaaca atcccatcgg
    21901 cagatcgtgc catcagtaga gttattggaa acgaaacaag atttatttga gcggctagat
    21961 gattatgacg tggtcttggt tgcttatgag gaatcagcaa agcaaggcga aaaatcaaat
    22021 gcagccaaaa ttcttagtga aacaaaacca gatagtcgaa tcttagctgt ctttggacca
    22081 gaaggtggat tatcccgcga tgaagtcgat tattttgtag aacacaaagg gatactttgt
    22141 ggattaggac caagaatcct tcgtacagaa acagcacctc tttatttatt aagtgctgct
    22201 agctatcaat gggaattaat gaatccttct ttcagctaac gttcttcatt aataaaagag
    22261 tatcgacaga aagaattgaa aaaatagtca acaatttgta taatagaaac aattatttat
    22321 acaatggata cgaaaaatcg tttgaaaaag cttttaaaaa gcgaacattt ccgtaaaaaa
    22381 acgtataact gcacggattt tgggacaatt atcaaacaga tatttgtccc gattcccgtt
    22441 ttaccgaaaa aagaaagggg gatcgattcc tgtgacaaaa gaagaaattt taacgggacc
    22501 cggtgtcata aagctcgtta gtcaatacat gggtcccgaa catgtagcat ttgttgagaa
    22561 agcatgcgaa tacgcgactg ctgcacatga cggacagttt agaaaatcag gcgaacccta
    22621 cattattcat cctatccaag tcgcaggtat attagcagat ttaaaaatgg atccccatac
    22681 agtggctaca ggcttcttac atgatgttgt tgaagataca gaaatcactt tagaagatct
    22741 gagagaagaa tttggcgatg acgttgctat gttagtggac ggcgtaacca aattagggaa
    22801 aataaaatat aaatcccacg aagagcagct agcagaaaac caccgaaaga tgctgctagc
    22861 aatggctcaa gatttacgag ttatcatggt caaattagct gatagactac ataacatgcg
    22921 tacgttgaag cacctgcgag aagataagca aagaaggatc gctcaggaaa ctttagaaat
    22981 ctatgcgcct cttgcacatc gtctagggat cagccggatc aaatgggaat tagaagatac
    23041 agcacttcgt tatctaaatc caaaacagta ttaccgtatc gtccacttga tgcagacgaa
    23101 gagagaagaa cgtgaaaaat acgtaagtgg tactgttgaa gatattcgaa tagcgacaga
    23161 agagctgggg atttttgcag aaatctatgg acggccaaaa cacatttatt caatctatcg
    23221 taaaatgaaa gatcagaaaa agcagttcaa cgaaatttat gacttgctag ctattcgagt
    23281 gatcgtagat tcaatcaagg attgttatgc tgtattagga gcaatccaca caaaatggaa
    23341 accaatgccc ggcagattta aggattatat tgccatgcca aaagctaata tgtaccaatc
    23401 tttgcatact accgtgatcg gtccggcagg aaatccggta gaaattcaaa tccgaacaca
    23461 ggaaatgcat gaaatcgctg aattcggggt tgctgcacac tgggcctata aagaaggaaa
    23521 aaatgaaaaa gtagaaccag atggtatgac gaaacaatta agctggttcc atgagatact
    23581 cgaacttcaa gacgaaagct atgatgcttc tgaatttatg gaaggcgtaa aaggagatat
    23641 ctttagtgat aaagtctacg tcttcacacc aaaaggagac gttactgagt taccaaaagg
    23701 atccggacca ttggactttg catacagtat ccatacagat atcggtaaca aaaccactgg
    23761 tgcaaaagta aatggcaaaa tggtgcagct tgattacaaa ttgaaaaacg gagatatcat
    23821 tgagatcatg acttctccaa attcatttgg cccaagtcgc gactggttga aattagttgc
    23881 tactagcaaa gcaagaaata agatcaaacg tttcttcaaa gcccaagatc gagaagaaaa
    23941 tgtgatcaaa ggccacgaat ccgtggtcaa atgtattaca gatctaggat ttacgcctaa
    24001 agatattttg acgaagaaca aactgcaaga agcactcgat cgttttaatt atcaaacaga
    24061 agatgatctc tatgcagctg tagggtatgg agaagttagc cccttgacga tggccaatcg
    24121 tctgactgaa aaagaacgta aagaacaaaa aatcgagcag caaaagcaag aagcagaaga
    24181 aatcatgaat cagccgaaaa aagaacctga caaaatgaaa gtacgtcatg aaggtggcgt
    24241 tgtcattcaa ggggtagaaa acttactaat tcgtatcagt cgctgctgta atccgattcc
    24301 tggtgatgat atcgttggtt atatcactaa aggcagaggg atatccattc atcgtcgaga
    24361 ttgtccgaat gttcagcctg acaaaccaaa tgtagcagaa cgtttgattg aagtcgaatg
    24421 ggaagataca tcgaatacac gaaaagagta tgatgcagat ttggaaattt acggctataa
    24481 tcgttcaggc ttattgaatg atgtacttca aacagtcaat gcgctaacga aaaatctcaa
    24541 cagcgttgaa gcacggacga ataaagataa aatggcgacg atccatttga cggttggtat
    24601 ccagaattta tcccacctaa agagtatcgt ggataaaatc aaagcagtac ctgatgtcta
    24661 cagtgtacgc cggacgaatg gataggagga cagatatgag agcagttgtt caacgggtaa
    24721 gtaaagctgc tgtgtcagtc gatcagcaag aaattggaaa aattggctac ggcctacttg
    24781 ttttattagg cattcatgaa accgatacgc aaaaagatgt ggactatctg gtaaaaaaaa
    24841 ttgcacaaat gcgtattttt gaagatgaac aaggaaaaat gaatattagt gtagaagatg
    24901 tgggaggaca aattttaagt atctctcaat tcacactgtt tgcggatacg aaaaaaggaa
    24961 atcgaccaag ctttgtggaa gccgcacgac cagaaacagc tattccttta tacgaatcat
    25021 tcaatgaagg aatcagaagt cgcggcatca cagtcgctac cggacaattc ggagcagata
    25081 tgtcggtttc tctcgtcaat gatggacctg taacgatcat tattgattct aaaaacaaat
    25141 aaagtaatct ggttttcact agtaaaaact atgaaacacg tcgcttaagt tagactgata
    25201 aactctaact taagtggctt ttttgtctgc aaaaagcgct tcttttgtca gcagtcggaa
    25261 aaaaagttaa gcttaaatta tacaagttat tttttatagg aggttgctga agatgaaaga
    25321 agtaccagta gtagatatca aaatcacaga tttaaaaaaa ttgtatcaaa aaggatacaa
    25381 catgttggag gagttacgcc atgaagcgga cgctcccgtc gtcaaagcaa agattttcaa
    25441 taaagaagct atcacgatct acggatcatc agcagcaaaa gtattttatg atccaaggaa
    25501 tttcaaacga aaaggtgcta tgccaaaatt agtattgaag acactttttg gtcaaggtgg
    25561 agtacagact ttggatggag ctgctcatca ccatcggaaa aatattttta tggatctaat
    25621 gacaccggaa agaatggaag attatcatcg tatcttagat aagaatctga cacaagcact
    25681 tgaagcacag catggtcaat ttgaactatt tgatttaagt aagatggttt tctttacatc
    25741 tatttgcgag tgggcaggta tcaatttatc agcgatttct aaagatgagg tcgaaaaatt
    25801 agcagaatat caaatctcta tgatcagcgg aacgtttact tctccgattg atcacataaa
    25861 aggtgtcgag aatcgcaaaa aatcagaaaa atgggcgcaa ggcttgattg aagaagctcg
    25921 acaaaatcct gtggctggaa aagaaaatgt ggcattatat gcttttgcca atgccacaga
    25981 tttagatggt cagcttttac ctctggaagt ggcagctgtt gaattattga acatcatccg
    26041 tccaacggtt gctctaactg tgtgggcggc attgatggga catgcacttt tcagtagacc
    26101 agatttgtat cagcaattaa aaaatgactt ttcgacgtta caagatccgt ttattcaaga
    26161 aatgagacgc tattatcctt tcttcccaat gctacctgcg atttcgctga aagaagtaga
    26221 agtagatggt tatcgtatac cagaaggcag ttgggttatt ttagatttat atggaacaga
    26281 ccatgatgaa cgaacagttg aagcgccaga ttcctttatg atcaaacggt atgtagggaa
    26341 agcaaaagat atttcctata aagaagaata tgagatgatt gcacaaggcg ggggaaattt
    26401 tcgacaaatg catcgctgtg caggagaatg gatcactctt catagtctac gtgtgttttc
    26461 cgatcagcta gtaaataagt ttgagttctc tgtacctgaa caagattgga cgattccatt
    26521 caatcagttt ccgacttatc cgaatagccg agcgctactt tacaagaatt agattagcat
    26581 aaacttatcg aaaaaaagga agatcaaaca gtgctgatct tccttttttc atattactat
    26641 aaattgataa ggtcaattga tcaaaatcca cgaaatgctt catcaatggt ttgataatct
    26701 tcattggata aatgcaaatc taaagcttgg acattgtcag atacttgctc tggacgctta
    26761 gctccaggta taactacaga cactcgtgga ttcttcatgt accaagctaa aacaagttgc
    26821 gcaggagtgg cttggtatct tttagcaatg gggcgaagta catcgacagc ggttaaaatt
    26881 tctctgaaac gttctccttg gaaatctgga tttctttttc gaggatctcc ttcaccaaat
    26941 tgtttttcct caccaagttc atattttcct gtcagcaaac cggaagcaag aggaaaatag
    27001 ggaacaaaac tgattttgtt tttttcaaga taagggaata attctttttc agcctgccga
    27061 tggatcaaac tgtatttatc ttctactaca tcgacatatc catctgcatt cgcttctttc
    27121 aattgttcta acgtgaagtt tgacacaccg actgctcgga tttttcctgc ttcttttaat
    27181 tcgtgcaatg tagcaactga ttcatttttt ggtgtgcttt catccggaaa gtggatataa
    27241 aaaatgtcga tgtaatcagt ttgcagacgt tttagtgcat cttccaccga ttgtttgaga
    27301 aactcaggag aattatcaaa tgttcgccct ttatttggta catgagcagc ttttgtagcg
    27361 atgacgacac gtgagcgatc atattctttt tccttcagta cctcgccaat cagttcttcg
    27421 gaacggccgt ttccgtaagc ataagcggta tcgatcaaat tgatcccgct attcaaagct
    27481 gtacgaacta cttgttttcc tgtctcatct tccaaaccgt caaaaagatt atgtcctcca
    27541 acggcatttg ctcctaatcc aagctgttct gcgtagactt gtgaatgtcc gattcttatt
    27601 tctgccatag ctgattcctc ctttttgtct agtctaaaac aaaataccaa aaagctgaac
    27661 taaaacgttt ttgtgagggg aaatagtcag atatctcttg actttgagac tggtttttag
    27721 taggttataa gtaatatcga atgtcaatga aagagcgagt aagtttttga aactttacaa
    27781 gagaggatca tcgaggctga aaatgatcta aagtttcatt agcctaaaga cactctggag
    27841 atggacgagt gaaaagccgt cccgcgtacg agcgttattc gtaagaggaa agagaaatct
    27901 ttcaaaatta ggtggtaccg tgtatgaatt tcattcaccc ttgttcatga tgaacaaggg
    27961 tgattttttt atttacatag ctaagaaagg gagagaaaac tatgagtttc caaagaccaa
    28021 aaggaacaaa tgatattttg ccaggcgaat cagaaaaatg gcagtttgtc gaagaaacag
    28081 cacgtttatt attcagagat tatcagtata atgaaatgcg tacaccgatt tttgaacact
    28141 atgaagtgat atcccgaagt gtaggggata caacggatat cgtttcaaaa gagatgtatg
    28201 atttttatga caaaggggaa cgccatgtga cgcttcgacc agaaggtaca gcaccaatcg
    28261 ttcgttcttt tgttgagcat aaattgttcg gcccagagta tgcgaaaccg ttcaaaactt
    28321 tttatatggg accaatgttt cgctacgaac gccctcaaaa aggacggtta cgtcaattcc
    28381 atcaaatcgg agtagaagca tttggatcag aaaaccctgc aactgatgtg gagagcatgg
    28441 tgatggcact tgatttcttc aaacagttgg ggatcacgca aatccggcta gtcatcaatt
    28501 cattaggtga taaagaaacg cgtcaagcct atcgtcaagc attgatcgac tatcttttac
    28561 cttttgaatc agagctgagt gaagactcta aacgccgcct tcatgaaaat ccattacgcg
    28621 tattggacag taaagacaaa cgagatcaaa aatttgtggc agaagctcca tctatcttag
    28681 attatctaag cgagcctgct caaaaacatt ttgataccgt tgtttccatg ctggatgcat
    28741 tggctgttcc ttatgaaatc gacagtaata tggttcgcgg actagattat tacacacata
    28801 cgatttttga aatcatgagt gacgcaccaa aaatgggggc acaagcaacg atttgcgcag
    28861 gcggacgtta tgacaatcta gtggaagaac taggtggtcc ttcaacacct ggcttcggat
    28921 ttgcaatggg tatcgagcga ttactcttga ctatggaggc agaggaagta gttatccctg
    28981 catttaatga gttggatgct tacgtggtcg cactcggaga cgaaacaaat atcgaagcat
    29041 tgaaagtggt ccaagcgatt cgaaactttg gtttttcagc tgaccgcgac ttcatgaacc
    29101 gtaaagcaaa agcgcaattt aagacagcag ataaagcgaa tgccaaatta gtattggtga
    29161 tcggtgaaga tgagcttgct agtcaaacga ttaatgtcaa agcaatggca agccgaaaag
    29221 aaaaaagttt tccattagaa gagatatatg aacattttga tgaagtctat gatgaaatga
    29281 ctttattcga gtaggaggaa aaaaataaat ggcacaaaga acgatctatt gcggattagt
    29341 ttccgaacaa caattagaac aaacagttac attaaaagga tgggtacaaa aaagacgaga
    29401 ccttggggga gtaatcttta tcgacctacg tgatcgtgaa ggaatcgttc aaatcgtctt
    29461 taatcctgaa atcaacaaag aagcatggga aatcgcggat aaatgtcgca gtgaatacgt
    29521 gatcgaagtg actggggaag ttagaagacg cggagaaaat gcagtaaatc ctaaaatggc
    29581 cactggtgaa ttcgaagtga ttgcaagtga aatcgtgatt ttgaatcaag caaaaacccc
    29641 gccatttcaa attgaagatg atcaagcaat cagtgacgaa atacgtttga aatatcgtta
    29701 tttggatctg cgtcgtccaa aaatgactaa aaacatcaaa ttaagaaatg cgacaacaaa
    29761 agcgattcgt cattatttag atgataatga ctttctcgat atcgaaacac cttacctagg
    29821 gaaatctaca ccagaaggcg caagagacta cctagttcct tcacgtgtcc atgctggaca
    29881 tttctatgcg ttgccgcaat ctcctcaatt gtttaaacaa ttgctgatga atgctggatt
    29941 cgaccgttat tatcaaatcg ttcgttgttt ccgcgatgaa gatttacgtg gagaccgtca
    30001 gcctgaattt acgcaagtag atattgaaac aacgttctta acagcagaag aaatccaaac
    30061 ttacacagag ggattgattg cgaaggtaat gaaagaagtt cgcggtatcg aagtcacatt
    30121 gccatttcct cgtatgacct atgatgaagc aatggctcgc tacggcagcg acaaaccgga
    30181 tacacgtttt gatatggaat tgatcgatct aagcgataca gtcaaagaag tagaattcaa
    30241 agtcttccaa atggctcttg aaaacggcgg tgtcgtgaaa gcattgaatg ctaaaggcgc
    30301 tgcagatcgc tactcacgaa aagacatgga tcagttaggt caatatgtag gacaattcgg
    30361 agctaagggg cttgcatggc tgaaagtaga agaagacgga ttgaaaggtc caattgctaa
    30421 attcatggga gaagcaacag aagcaatcat taaagcaaca gatgcaaaac caggtgactt
    30481 gctgatgttt ggcgcagata aaagtgaaat cgtcgctgct gcattaggtg ctatccggac
    30541 acgtttagga aaagaattag gactaattga tgaatcgaaa ttcaatttct tatgggtaac
    30601 tgattggcca caatttgaat tttcagaaga agaaggtcga tatgtctctg ctcaccatcc
    30661 attcacgatg ccaaaagaag aagatatccc gttattggct gaagaccctg caaaagtcta
    30721 tgcagaagct tatgatatcg tcttgaacgg ttatgaatta ggcggaggtt ctatccgtat
    30781 tcatactcgt gagcttcaag aaaaagtact agaaactcta ggctttacaa aagaacaaat
    30841 ggaagaacaa tttggtttct tgttaacagc tttagattac ggattccctc cacatggcgg
    30901 tattgcatta ggattggacc gttttgcaat gttattagcc ggagaagata atattcgtga
    30961 agtcattgcc tttcctaaaa acggaaaagc agcagatgtg atgagtgatg caccaagtat
    31021 ggtttcgcct ttacaattgt tcgaattgaa tattgatgta acgaatatag aagaatagcc
    31081 gataaaaagg taaaaaggat ttgtcgaata cgcttctttt gacaaccttg atttaattga
    31141 aaaacacttt ataatgaagc cataacatat aaagcggggc ttttccatga aaaaaacatt
    31201 cgaaaattgg gcttatcatg attacacgac caagctttcg gtatctatcg tttatgcgtt
    31261 gatcgcatca gtcgcattga atttctttta tcagccagga catatttatt caagtggtat
    31321 tactggtcta gctcagattt tgacgacttt gtcaaaatca ctgataggat tcgaagtacc
    31381 ggtatcaaca actttgtatt tactgaatat acctttgttt gtattggcgt ggttaaaaat
    31441 cgggaagaag tttacaattt tcacttttat cacagtcact ttgacctccc tttgtatcca
    31501 tattttaccg gaaacagtcc tatctaccga tccaatcatc tgtgcgttgt ttgggggggc
    31561 tgtgatggga ctaggtattg ggctagcgtt gagaaacggc ctatcatcgg gcggtctaga
    31621 tatcgtgagt atcacgattc gtaaaaaaac aggaaagtcg attggttcta tttcgatcta
    31681 cttcaatgca ttgatcgttt ttgttgccgg aattctattt ggctggcaat atatgtttta
    31741 cagtacgttg tctattttcg tcagtggaaa agtaactgat gtcgtttata ctaaacaaaa
    31801 gaagatgcag gtaatgatcg taacgaaaca tccagaaaaa gtagtaaatg aaatccaaaa
    31861 ctgtatgcgt agagggatca cgatcatcaa tgaagcagaa ggtgcttata agcatgataa
    31921 gcagacagta ttgatgacga tcgttacacg atacgaactg cctctactta gagaagcaat
    31981 gaaagcttct gatccacaag cttttgtaag tattgcagaa aacgtccaga tacttggtcg
    32041 tttctatgag gatggcattt agatcgagtt tgacaaaaat tcatgaaata ctgctgtaga
    32101 cagacgttcg tttgtctgca gtttttttct accatagtag aatcagcaaa gaaaaactgc
    32161 ttttttattt gaaattttct taaagttgaa aaaaagcatg tttatttttt taaatttatg
    32221 ggatgataga aaaaaatagt agagaaagga cacgattcta cttgctattt tcacttaata
    32281 cccgtatatt acgaatgaaa aaagtttatg aaaagttgga atattgaatg gaaaaacaaa
    32341 aaaggttaaa aaacagccgc tacatcactg ggtttgatgg gctccgttca ttagctgtgg
    32401 tgggtgttat cttctatcac cttctgccaa ctagtatgaa aggcggctat ttgggcgttc
    32461 cgattttttt cgtcgtatct ggttatttga tcacggatct gctgcggcag gaatgggaac
    32521 aaaatggaaa aatcaatatt tggcaatttt atgtcagaag aatgaagaga ctctatccgg
    32581 cacttgtttt tatgcttgtg acagcttcgg cttatatcac tttgtttcag cgagggctgt
    32641 taaacaatct tcgaggagtt gtggtcagca gcttactgta tgtcaacaac tggtggcaaa
    32701 tcaataacgg tttatcttat ttcgatcgat ttgctaatga gtcaccgttt acgcatatct
    32761 ggtctttagc agtagaaggt caaaactatt tggtttggcc gatcttgttt gtattgttga
    32821 tggtatttgt tcgtaaaaga aaatggatct tttatactgt gttaggtaca tccttcctct
    32881 ccgccatctt gatgatgatc ttgtatacac caggaggcga tccaacccgt gtttattacg
    32941 gtaccgacac tcgtctgttt tctatatggt tgggaagtgc gcttgcgttt gtttggccaa
    33001 gtacgcgttt aaagaaaaac atcccgaaac aagcgaaaaa tattctgaat atcgctggag
    33061 gaatctcgct tttggcactg attctttgct tcttcttttt agatgatcat tacaatttca
    33121 tctattacgg aggaatgctc ctagtgagtc tgttatgcgt agtgctagtt gcagtgacag
    33181 cacaccccgg agcaagtttg aatcgatggc tgacaaatcc agtatttact tggattggca
    33241 aacgaagcta tggcatttat ctgtatcagt ttccagttat gattttttat gaagcaaagg
    33301 tgactgatat tgccgatcat gttttgttgc atactttagt ggaaatcaca ttgattctaa
    33361 tcatcagtga actttcttat cgatatgtgg agcgtccgct agcacgtttt gattatggtc
    33421 gtacattcca agtgatgaaa ggatggttca gcaaaccgat catcagtaag agcaaaccat
    33481 gggttgttcc aggcacatta cttgtagcaa ttgcactcgt tggtttcgtt acggcaccga
    33541 aaaacgctgt aacagccgat caaaaacaac tgcaggcaaa aatcgctgaa agtaaaaaat
    33601 tagcagaaga aaccagaaac aattcagaaa acaccactag ttcggttgac caagcgatcc
    33661 ttgataagta cgagttgtcc aaggcacaag ggaataaggc acaaaaatta gaactaacgg
    33721 catttggtga ttcagttatg ttggatgctg caacggatct acaagaactt tatccaaaag
    33781 tagtggtaga tggagatgtc ggacgacaat tatatgccag tgtaccgtac attgaaaaat
    33841 taaaggaaca agatttgttg aaagacactg ttctgattgg actaggaacg aatggctcat
    33901 tctcggaagc tcagtttgat agtgtgatgg atgcaatcgg tgatcgaaaa gtatactggg
    33961 tcaatgtccg agtaccgacg aagcgctggc aaaatgacgt gaatgcgatg cttgaacaga
    34021 tgacgaaaaa atacgacaat atgacgctga ttgattggta cagctacagt aatgaccata
    34081 gtgactggtt ttatgatgat caagtccatc caaatcctga agggatgaca cattacattc
    34141 acttagtcag cgaagccttg ctaggaggaa gttcaagtac gaacagcagt gagacaaacg
    34201 tgacagaatg atagctacaa aaaacttcag gcaaaaacat ttgtttttgc ctgaagtttt
    34261 tttatattta ccgtgttttt aacattcata tagattcagg aagcaaaacg gttgagtgtg
    34321 tctgtaaata acgttctttt tgttttcggg tgagtttttt gaatgcagct tctgcttttg
    34381 ttgcttcgct tcttgaagaa aatacttctg catggatcat cttaacaggt cttctttttt
    34441 gaagacgagt atatttagca ccagtaccat tgttatgttc ctctaatcgt ctagaaagat
    34501 cggttgtata tccaccataa aatgtctgat ctttacagaa taatacgtaa aaataatgtt
    34561 catttgccat agagcatctc acgaatctct gcagtgtatt ctccatccat attgtaagtg
    34621 atcaatggtg gagcgacttt gaatccgtct aatttgcctt ctttgattcc ttcaactaac
    34681 aaaatatttg cctcttttcc aggttttggg taaacaaatt ggatcctttt aggtgcaatt
    34741 cgatagtctt ccatgacctg aatgatttct aagaaccgat caggacgatg gaccatagta
    34801 aagcgtccat ttgtttttag tagcttactt gaaatatcga tcacttcttc taacgtcgta
    34861 tgaatctcat gacgggcgat tgccaggtgt ttattagggt tcgttttatt tgttggcagc
    34921 cctttgaaat aaggtggatt acagacgact aagtcacaag aattatgtcg aacgacagat
    34981 aagctgtctt tcagatcgat ggtgtggaca gtcatttgtt catttaaatg gttaagcgcg
    35041 atactacgtc ttgccatgtc tgctagacga ggttgaagtt cgatagcgtc gatagccgcc
    35101 tgggttcgtt tacttaaaaa aagtccaact gcgccatttc ctgcacaaag gtcaacaatc
    35161 ttcccttttt taggtacacg ggaaaagtga gcaagcagca cagcatctaa agaaaaagaa
    35221 aacactttgg aactttggat aatcttgata tcttctgcgt ataattggtc gattcgttcg
    35281 tcttcgtgaa gcatggattc cctccaaaat gaaaaaaata gtcgtctgta ttatactatt
    35341 tttattaaaa agaaccaagg tggcttgtca aacctctatt ttttatgcat actatgacca
    35401 taagaaggga aaggaagaga ctatgtttta tcgatttatg cgcggggtag ttcgagtact
    35461 attagcctta gttaatggaa atgcccgcta tgagaataaa gaagttttac cgcaagatga
    35521 gaattacata ctagttgctc cccatcgtac ttggtgggac ccattatatc tggcggtagc
    35581 tgcagcaccc aaggaattca gctttatggc aaaagaagaa ctgttcaaaa atccagttct
    35641 gcgatttata ttaactcgat ccaatgcttt tccagttaaa agagaaaatc caggaccaag
    35701 cgtcattaaa acacctgtaa agattttgaa atcgacaaat ttgagtttga tcatgtttcc
    35761 cagtgggaca agacatgcta cagaacttaa aggcggaatg gcattgattt ccagaatgtc
    35821 taaagcgaaa atcgtgccag ctgtatatca aggtccgttg acacttgggg atctgttcaa
    35881 gcgtcagaga gtgacagtgc gtttcggcga accaatcgac ttatcagata tcaagaaaac
    35941 ggataaagaa ggtatggcgg agatcgaacg acgaacacaa gcagcttttg acaaattgga
    36001 caaagaagtg aaccctgatt tcaaatatga agtcaaaaaa aaataaaatg ataagtttat
    36061 gcgtgggcgg tcttttgaat ctactgtcct gttcagttca gactttttca atgaaaacga
    36121 gggagagacg tcaagtctgc cctctttttg cgttccaata tgtaaaatag aagacaggtg
    36181 tcatgtaatg gatcaaagtg ttataataat tagaaggaca ttttttgagg tgattgaatg
    36241 cgttttttac atacagccga ttggcatatc ggaaaaaaac tacaaggtta tgacttgatt
    36301 gaagaccagc gtcatgtact atcttctata ctagatatcg cgaaagaaga aaaagtagag
    36361 gcaatcgtga ttgccggaga cttatatgat aggagtgtcc cagctgttga tgccgtagaa
    36421 ttatacaatg aattgatggt cgattggaat ttaaaggaaa agatcccgat ttttgctata
    36481 tcaggaaatc acgatagcag tacgagactt tcagcgggta cgccatggtt cagttattcg
    36541 aactattttt tgcgaacaca gctagcagaa gcatttgaac cagtcgagtt taaaaacgta
    36601 caatttttct ttcttcctta ctttgaacca attgcagcga gattatattt tgaagatgac
    36661 aatatccgaa cgatcaagca agcggtagcc aaggtgatag ataaaatgca ggagctattt
    36721 gattcagaaa aaaaacaagt attgattagc catttttttg taatgggaag tgtaaaatct
    36781 gattcggaaa cgaaaatcga agtaggcggg ttggattcga tccctggtga actacttaca
    36841 ccgtttgatt atgtagcact aggacatttg cataatcaag ctgctttgag acaggataat
    36901 gctcgctata gcggttcccc attgaaattc tctttatctg agatcaacca aaaaaaaggc
    36961 gtatggatcg ttgacctgac aacaggcctg gagttgaatt ttagggagat cgaacccctg
    37021 catgatattg aagaaataac agcgagtttc aaagaattgc tggatcctgc cttttatcag
    37081 tccgtcaatc gggagaatta catctatatc tatctcactg atagaacgat catcccgaat
    37141 atgatgaacc agcttcggca aatatatcct cgtattttgg ggattgaacg ggcaaacggt
    37201 cgagcagaac aaacaaagcg caaacgaaaa gtactagaaa tgaaagatcc tcaaaaatta
    37261 gcagaagcat tttttagtga aatgacggaa gagcagctaa ctgcaaacca agaaaaatgg
    37321 ctcggagaaa cgttgcaaga aatcatggaa atggaatgat caagaatgaa accgaaaaaa
    37381 ttacaactta aaaattttgg tccttttatc aatgagaccg tagatttttc acgtttgaca
    37441 gaagcaccgc tttttttgat cagcgggaag acaggagctg gcaaaacgac gatttttgat
    37501 gggatcacct tcgcactttt tggtgaaact tccggaagac ttcgctctgg aaaagagatg
    37561 cgttctttgt ttgctacacc agacgaagaa acaagcgtga ctttttcttt tgaacatcag
    37621 cagatgagct atgaaatcga acgaaaacca gaacaagttt tagcaaaacg aaaaggaaac
    37681 ggaacaaaaa aacaggcagc caaagtaacg ttgaccattt ttgatgggaa aggaaaagaa
    37741 ataaaacaaa tcacaaaacg tacagaagca gatcagttga tcagagaact gatgaatctc
    37801 gatgcgaaac agttttctca aatcgtttta ctaccccaag gagaattccg taattttttg
    37861 gtttcatcaa gcagtgataa agagactgtt ttacgtcatt tattcggtac tcaatttttc
    37921 caacagttca atgagcgatt aaaagaaaaa gcaaaacaac agcaacaaaa attggatcat
    37981 ttagagcaag agctgcatct tctgcaaaaa aggtttgttt tagtcaaaga agaggaacca
    38041 gcagcagggt ttgaagccgt tttagcccaa tggacaaacc atcaggcaat actcgaaaaa
    38101 caaatcacgg aagaaaaaga agctctaacg gaacttcagg aaaaacaaaa gcaactagaa
    38161 aattcctact atcgttttga aagcttgaaa aaaagttatg aagaaaaaac gatattaata
    38221 aacaagcaaa aggaattagc tgctcaaaaa gacgaaatag aggaaaagaa acgatggatt
    38281 gggtattatg aatttacgca acgattagtc gaaccaatcc agcgcctaca agaaataaaa
    38341 gttgaaaaaa tagaactgtc acaaaaaagt agtgagcaaa caaagaaact agcgatgact
    38401 acgcagaatt atgaagagtg gcaaaaaaat gaagcaaacc gcgtacgccg acaaacaaaa
    38461 atcaaagaag ctgctcaaaa actgcaaaac aaacagatga tggtgccaat tgtcgaatcc
    38521 ttacgtagta aaaaacaaga cgcagaacaa ttaacaattt cattggataa agaagaattg
    38581 aatgccgaga agctgtatca aaatctcgct atctatcagg aaagaactcg aattcttcaa
    38641 gaaaatttac tggatcagga aaaactgcaa gaagatcgtc ttgcttttgg acagttaaaa
    38701 tatctagatg aaaagcagca agaaatagaa aaacaaaaag caaaagacac tgggtcgctc
    38761 gcacagataa gagaagaact caaaaaagca actgaagaaa taacaaaaaa tagtcagcta
    38821 ttgaaagaac agacagaaca agcagaacag ctgaaaagcc aatgggcaaa gcagcaaatt
    38881 gctcgtcttc agcttttttt gcgtccaggg gagccatgtc ttgtttgtgg atcaacggaa
    38941 caccccatac aacaattaaa acacgaacag ccaaataagg aagatatctt aaaagtagaa
    39001 caacaactgg cagaagctga gtctgctgta gaaagaactc agcaaatcat tgccaaaagt
    39061 gaagcacatg aaaataatct tcaacaacaa ttatcagatt tagaacaaaa aatcatggca
    39121 acgaatatac aattggctga acaagaagaa cacttgcaac aggctttgaa aaaggcattt
    39181 cctgagataa cagaacaaaa aacaaaaaca actcttgtag taatcgaaca atctttagat
    39241 agacgaaaaa gcaagatggc caatgcaaga atagagctgg aagaaataag acaacaagca
    39301 gaaaagctcg aacaacaatt agctgtctac aaacagcagc agacagaaaa aaataatcag
    39361 ctccagcaac tgcaaggaga aatcaaaagt ttagaacaac aattgcaaga tacggatagt
    39421 aactgtttag aagaggagat acgacgactt gaaaaacagt tagaagaaga ctcgaatcaa
    39481 ctagctgttg agcagaaagc aggagtgcaa ttgttgcaag atcttcatac gcttcggaca
    39541 cagcttgatc ttcaacatga acaaatagaa aaaatagatg aaaaaataga aaaggaacaa
    39601 gaaagaatag ctaaaaagtt agaaagccag tcgtattttt caacaattga agaaatctgt
    39661 gcatttgcac aacagcaagc acaatataaa gaaaaccaac gtacagttac ttcttatcat
    39721 gaagagcaat tagtgacagc tgaccggctg cgtcaattag aaaatatcca gctaactgag
    39781 acattcccag atacagaaga gatcagccaa cagttagaag aaataagacg tatgatcgaa
    39841 ataaagcaag aaaagatata cggtttacaa gaacaaaaaa ttagtaatca aaaaatctac
    39901 gatgaatgtc tttcgattta tcacacaagc cagacgaaat tagatgagct tacgcaatta
    39961 cagcagcttt cgcaaacatt caacggagaa aatcctaaga agactagttt ggaacggtat
    40021 gtgcttcagg tttatcttca agaagtgtta caagtagcaa atgatcatct ccaacgttta
    40081 acgaaaaatc gttatcaatt tgagctagcg gataccattg gcagttatcg agggaaaacc
    40141 ggattagaaa tcaatatcta tgatgatcag gcaggtatgt ctcgaagtgc gcataccctg
    40201 tctggcggtg agagttttat tgcagcactt tctttagcat tagctcttgc cgatgtgatc
    40261 cagacacaag ctggtggtgt agcaatcgat gcattgttta ttgatgaagg atttgggtca
    40321 ttagatgaag aagctttgga aatggcaatg gaagctttag aaacgatcga aagtgaagga
    40381 agaatgatcg gcatcattag tcatgtaaga gaattgaaag aacgagtatt acaacaaata
    40441 agaattgata cagaaggtag cggacaaagc aaaatacgct atcaacttgg ataaaaaggg
    40501 agattggtaa ctatgaaatg gagtattcca gaaaaagtca ttgcacgtgg acgtcaatac
    40561 ttgcaagaag gccgagtgtt atcggttgtc cctgaccaag aagaaaacgt gtggcatgca
    40621 gaagtcttgg gcagtgaatt gtatatggtt gatttggatg gtacagcaaa agagatagat
    40681 tactgccaat gtccctattg ggaggaacat aaatattgta agcatacagt tgctgtggaa
    40741 ctttatttac ggtcgaaaaa tctatctcgt atcatgaaaa aagaccagcc aatgctagaa
    40801 ccggtaaaag caacaagtga gggagaaatc attgcaaaag gtttttctcg tctaaaaaca
    40861 caaaacaatc ctcaagcggt gcaacctttg attattgaat accaagtaga aacgattgag
    40921 actaatcagt atcacccaga gctttctatt ttggcacttt acttgcgtat cggttcattg
    40981 gcatcaccga aaaaaacata tatcgtaaaa aacatctatg attttttaca agcttacaca
    41041 gaaaaagaaa cttacactgt taataaacag taccagtttc gtctagataa acgggcgttt
    41101 caaaaagaag atcaaaaaat actcacgcat cttgcaggaa gtgctcagac gcatcaatta
    41161 ttaggtacga acggcttaca agtcaaagga aaactagata aaagatatct gcttctccca
    41221 gtagaacaag cccgcttcct gttagagcag atgaatcaga ctacacgttt gcatctgcag
    41281 ataaatgaac aaaacgatca aggaatacaa ttttccgatc aaaacaaacc tttatcattc
    41341 aaagtggaaa aatttggaga agattatttg ctgcaagcat tgaatgattt tgattttttc
    41401 tttatgcatt atcagtgggg agttatccaa gggacatttt attctctgac gaaatatcaa
    41461 caaacggttt atcaaacttg gaaacaattg attcgccgat tggagaaacc agaagtagtg
    41521 ttcaagaaaa aagaattacc gtctttgttt aaagagatta tccctctgct gtcagagatc
    41581 ggcgacgtag ctattgcccc tgcagtagaa gaggaagtag cagatatccc cgtcgaattt
    41641 attttctttt tccgaaaagc aaaaggaaaa atccaagctc gagtcgattt cgtctatggt
    41701 gaagtcatct attcgactga cccgaagcat gaggtctcga cagaacaggc ttttcaggtg
    41761 ttacgtgaca cagtagaaga gaaacgagta cttgatctat tcagaatgta tcgctaccag
    41821 aaaaatgaaa ctggttatga acgtccattg ccaagcgggg aagaactata tgcctttttc
    41881 cgcacagaac tatctgtctt ccgtcagttt ggtgaagtca gacttggaag aaaattgcga
    41941 gagttgtatt tagatgcgca taaacatcaa ccgaaaatcg aagtaaccga gaccggttca
    42001 tggctcgata ttcgattcga tgtgacaggg atagaggagc aagaaatcga tcatgtcctg
    42061 caaagcttgc tgagaaatga tgctttttat acattagaaa atggtcaggt tctttctttt
    42121 gattcagaag aatttcaaca aacaagccaa gtgttgcaac aattacggga atcgatacgt
    42181 acagaagaag gaacgatcca tgtacctaaa aatcaaggat tgatcattca aaatcaattg
    42241 gaaaaaagca atgctacttt tagtgaatcg ttccaaacga tggtacaaga tctcattcat
    42301 ccagaaagat accaggcaca gcttcccaaa ggattgaatg caacgatgag agattatcaa
    42361 aagcaaggtt ttcgatggtt gaagatgtta ggtcattatc agtttggcgg tattttagcc
    42421 gatgaaatgg gacttgggaa aacactacag acaattgcct ttttactttc ggaaaaagaa
    42481 gaacggaaaa gcttctctgc tttgatcgta gcgcctgcga gcttaattta caactggcag
    42541 gcagaggtga gaaaattcgc cccttcttta agtatccaag taatcaatgg gaataaaaaa
    42601 gaacgtgaag aattactggc taaagacaca gatatccgag tgacttctta tgccagctta
    42661 agacaggatc tagctaatta tcagtcgcaa aaaattgatt atttgattct tgatgaggca
    42721 caaatggtca aaaatagcag tacgaaaact gcacaagcat tgagagaatt agctgtacct
    42781 cagcggtttg cactgagtgg gacaccaatc gagaataatt tagaagaatt gtggtcattg
    42841 tttgcaacga ttatgccagg atttttcccg actaaaacaa aattcaggga acttgccgca
    42901 gaagaaattg cgcaaatgat tcgaccgttt attttacggc gagataaaca aactgtgttg
    42961 aaagacttgc cggaaaaaac agagatgaat ctatattctg cacttacaga agaacaaaaa
    43021 actgtttatt tagcttactt gcgtcaaatg cgtgaagaaa tcacatcaat ggattctgaa
    43081 gcattcaaga aaaaccggat cgggatactt gctggtctga caagactgcg acaaatttgc
    43141 tgcgatcctc gtctgtttat tgaagattac caaggcggtt ccggcaagct cgaacaagta
    43201 aaagatctac tggtagctgc caaagagaac aaacgaagag ttttgctgtt ttctcaattt
    43261 acagggatgc tgactatctt gcaagaagag ttagccgagc tagggatctc gacattttat
    43321 ttaagaggca gtacgaaacc acaagatcgg ttaagtatgg tagacgcatt taatgctggc
    43381 gaaaaagatg tttttctgat ttccttaaag gctgggggaa ctggattgaa tctcacggga
    43441 gcagatacgg tcatcttgta tgacctttgg tggaatcctg ccattgaaga acaagctgct
    43501 ggacgtgcac atcggatcgg acaaaaaaat gtggtagaag tgtggcgtat gatctctgaa
    43561 ggaacgattg aggaacgcat ggattcactc cagcaagaaa aacgcgaact gttccaaaaa
    43621 gtgatccaag gtaatgaaga acagttgacg aaactgactg aagaagacat ccgcatgatt
    43681 ttaagtgtag gagaaatcga ggagtaagag actcgaaaaa gcgttcagta atgggtaaga
    43741 aagcctttct aaagaagcga ttgtttattt gatttaaaaa atagcaagga ggctgggatt
    43801 ccattttatc ccagcttcct tgctatcatt tttttatttc tatttttaaa ggttatacaa
    43861 agattgtctt cattgtctct aacagctgat caaaagaaga aatctcgata tcgcaaattg
    43921 gagtctgttc aattttgcgt tctcgatggt tgaaccaaag cgcttgccag ttagcacttt
    43981 ttgcacctag aacatcattg tcgtaattat cgccaacgta taaggtctct tctggaagca
    44041 tatgaaattc tttctcagcc agctgaaaaa tctctttttc tggtttttgg aaacctgttg
    44101 cttgagaaat gagcatattg cgggaaggaa tccaattgtt caattgaagt tgcttcagtt
    44161 tttttgtctg atggtcagtc ggcccatttg tgataattcc taatgggaca ttcttttcct
    44221 tcaagaaatc gagggttttt ttgacctcct catgcaagca gatattatca agttcttcct
    44281 cgtaaatttt ttgaaataag aggccatctt cttccgtaat atgagggtag tctaaatctt
    44341 ttagtgattg gctgatccga tgtgctcgca tatattctag tgtccaatct cctgccatta
    44401 cttttgggaa gttttcatca ctatgatggc ggaaccggat atatagtgga tgcatatctg
    44461 catctgaaac aagcggaacg actcttttga ccgcgtttcg aaatggctgc tgctgatcat
    44521 acatcgtatc atcaacatca aacacaactg atttaatcaa aattttacac gcctttcggt
    44581 tttcattgat tttttcacaa atccttgact attgtaacag aaaaaattgt ctaaaaaagc
    44641 tgataaataa aggtttttct tactatattt ctatttcctt gacagaataa ggtttttata
    44701 tttcagtttt tttcactaaa aatcgtgaaa cacgtcaata agtttgatga acaaattaat
    44761 cattatggta gaagtcgatt gatttatttt aatgcaatct ctgtggaatt ttcgaaagat
    44821 ttattttttt aatacagtct caatataact attcaaacat aaaataacgt tatttgattt
    44881 atttgtttat agtaaatttt atttagtaat cattgcttta aaatactacg cttatataac
    44941 agagaaaata agcgttataa taaagaacag tattatttaa aatgacagaa aacattacta
    45001 ttaaagaaat aaaaaacata aaaaatctta agaaatcggt ttcatttagc ttttgagata
    45061 aaataatagt acagttttat acgctgtttc atatgtttag aaaatttgaa ttagatttga
    45121 aaactctaat ttttaaatga taaaaaaagc gagaatgctg gttttactgt atattaacct
    45181 tagataactt tcattttttt aaaaaaatta tgaaaaaaag gtagctattt aaaagttgat
    45241 tatgtataat agaaacagat gggagattat tatgatcttc tgttacaaaa aagtgattct
    45301 tatcacgaaa aggagtggtg cacgttgtta acattatata cttccccaag ttgtacttcc
    45361 tgcagaaagg ctcgtgcgtg gttgcaagaa catcagattc catttgttga acgtaatatt
    45421 ttttcagaac cattgaacag ttctgaatta aaagcgattt tacaaatgac agaagacgga
    45481 acagaagaaa tcatctcgac acgttccaaa gtattccaaa aactgaacat ggatttagat
    45541 gatctgccgt tacaagaatt attggaactt gtgcaaaaca atcctggatt gcttcgccgt
    45601 ccaatcatga ttgatgataa acgtctgcaa gttggtttta atgaagatga aattcgtcgg
    45661 ttcctaccgc gcgatgtacg acaattagaa ttacgtcaag cacaattgat ggctggatta
    45721 tagaaggata atacgaaact tggaaaag
//
LOCUS       DADGKS010000017        40034 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.017, whole genome shotgun sequence.
ACCESSION   DADGKS010000017 DADGKS010000000
VERSION     DADGKS010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40034
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.017"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(51..632)
                     /locus_tag="JXV47_001024"
     CDS             complement(51..632)
                     /locus_tag="JXV47_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IDEAL domain-containing protein"
                     /protein_id="HAX1487082.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(638..1897)
                     /locus_tag="JXV47_001025"
     CDS             complement(638..1897)
                     /locus_tag="JXV47_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAX1487083.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(1899..2945)
                     /locus_tag="JXV47_001026"
     CDS             complement(1899..2945)
                     /locus_tag="JXV47_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487084.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(3180..3455)
                     /locus_tag="JXV47_001027"
     CDS             complement(3180..3455)
                     /locus_tag="JXV47_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008214712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HAX1487085.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(3698..5008)
                     /locus_tag="JXV47_001028"
     CDS             complement(3698..5008)
                     /locus_tag="JXV47_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HAX1487086.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(5190..6419)
                     /gene="rpsA"
                     /locus_tag="JXV47_001029"
     CDS             complement(5190..6419)
                     /gene="rpsA"
                     /locus_tag="JXV47_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HAX1487087.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(6554..7234)
                     /locus_tag="JXV47_001030"
     CDS             complement(6554..7234)
                     /locus_tag="JXV47_001030"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HAX1487088.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(7283..7918)
                     /locus_tag="JXV47_001031"
     CDS             complement(7283..7918)
                     /locus_tag="JXV47_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAX1487089.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(7984..9387)
                     /locus_tag="JXV47_001032"
     CDS             complement(7984..9387)
                     /locus_tag="JXV47_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HAX1487090.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWGTILLNLFKKNMEH"
     gene            complement(9374..10405)
                     /locus_tag="JXV47_001033"
     CDS             complement(9374..10405)
                     /locus_tag="JXV47_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487091.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            10436..10657
                     /locus_tag="JXV47_001034"
     CDS             10436..10657
                     /locus_tag="JXV47_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HAX1487092.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(10822..11559)
                     /locus_tag="JXV47_001035"
     CDS             complement(10822..11559)
                     /locus_tag="JXV47_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HAX1487093.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(11712..13052)
                     /locus_tag="JXV47_001036"
     CDS             complement(11712..13052)
                     /locus_tag="JXV47_001036"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HAX1487094.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(13289..14812)
                     /locus_tag="JXV47_001037"
     CDS             complement(13289..14812)
                     /locus_tag="JXV47_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HAX1487095.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(15190..15801)
                     /locus_tag="JXV47_001038"
     CDS             complement(15190..15801)
                     /locus_tag="JXV47_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAX1487096.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(15924..16049)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(16131..16847)
                     /locus_tag="JXV47_001039"
     CDS             complement(16131..16847)
                     /locus_tag="JXV47_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAX1487097.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(16853..17422)
                     /gene="scpB"
                     /locus_tag="JXV47_001040"
     CDS             complement(16853..17422)
                     /gene="scpB"
                     /locus_tag="JXV47_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HAX1487098.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(17406..18203)
                     /locus_tag="JXV47_001041"
     CDS             complement(17406..18203)
                     /locus_tag="JXV47_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HAX1487099.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(18173..18544)
                     /locus_tag="JXV47_001042"
     CDS             complement(18173..18544)
                     /locus_tag="JXV47_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAX1487100.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(18563..19450)
                     /gene="xerD"
                     /locus_tag="JXV47_001043"
     CDS             complement(18563..19450)
                     /gene="xerD"
                     /locus_tag="JXV47_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HAX1487101.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(19546..20019)
                     /locus_tag="JXV47_001044"
     CDS             complement(19546..20019)
                     /locus_tag="JXV47_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAX1487102.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(20124..20987)
                     /locus_tag="JXV47_001045"
     CDS             complement(20124..20987)
                     /locus_tag="JXV47_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAX1487103.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(21183..23282)
                     /locus_tag="JXV47_001046"
     CDS             complement(21183..23282)
                     /locus_tag="JXV47_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAX1487104.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(23502..24611)
                     /gene="rpoD"
                     /locus_tag="JXV47_001047"
     CDS             complement(23502..24611)
                     /gene="rpoD"
                     /locus_tag="JXV47_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HAX1487105.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(24635..26476)
                     /locus_tag="JXV47_001048"
     CDS             complement(24635..26476)
                     /locus_tag="JXV47_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HAX1487106.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(26658..29051)
                     /locus_tag="JXV47_001049"
     CDS             complement(26658..29051)
                     /locus_tag="JXV47_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAX1487107.1"
                     /translation="MFLILEHARLKHVIIFESWRKMEKKKMNGLTQQEVVQKMASGQQ
                     NDYQEDASKSTKQIFSDNILTLFNFLNFGIGICLLFVGAYSNMAYLAIIVVNIVIGIY
                     QEIHARNLVRKLSIVSQSEVLVIRDGKEQSISTKELVLGDLVKIGAGEQIPADLQVIS
                     GRAEANEALLTGESDLIVKETGAELLSGSFLTSGSVMAEVIRVGADNYAVRLTSEAKT
                     HKAIRSELVDSIRKVSKFTSFVIIPLGIILFLEALFIRDASIKISVIASAAALLGMLP
                     KGLVLLISIALTTGVTKLAKKRILVQDMYSIETLAHVDTLCLDKTGTITEGKMSIQRV
                     EALHPLYEKAIPEIMGTYLAESSDNNITMRAMRDYFELSNRYDVTNKVAFSSDRKWGA
                     MEFPELGVVYVGAPERLVEEDRLPDSLKTAQANGYRVLMLGIAPNQQLNEEKPAFVEP
                     VALFEIDDPIRKNAQETLAYLHEEGVDLKVISGDNPFTVSNIARRAGLPNYDAYVDLS
                     QITEEMEVREAAHRYTVFGRVSPQQKKLLVNELKESGRTVAMTGDGVNDVLALREADC
                     SIAMAEGDGATRQIANLVLLDSDFTTLPEVLFEGRRVVNNVTKVSGIFFIKTIYSFIL
                     SIICAVTAIGFPFIPIQITLIDLAIEGYPSFFLSFEQDKRKITYRYLPTALINALPNA
                     LLVVVNIIAVYLLGKTFAWGNAETTTLMYYLLIGISCMAVVKACYPFNPLRIFLAVTT
                     IVGIYVAAMLFHGILEVNLGLGESVGYFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(29158..30018)
                     /locus_tag="JXV47_001050"
     CDS             complement(29158..30018)
                     /locus_tag="JXV47_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HAX1487108.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(30077..30598)
                     /locus_tag="JXV47_001051"
     CDS             complement(30077..30598)
                     /locus_tag="JXV47_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HAX1487109.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            30918..31637
                     /locus_tag="JXV47_001052"
     CDS             30918..31637
                     /locus_tag="JXV47_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAX1487110.1"
                     /translation="MKKEKKYAKMPDGSEIYYEKSGQGFPLFLLHGNDGSGRFFSEQV
                     PVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEKIDQADFLGFSDGAN
                     LALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVWLLSLFRPSLRKNLL
                     VIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKTIPKASFVLVKEQGH
                     ELARKDPERFNREVLQFLSET"
     gene            31663..34254
                     /gene="mprF"
                     /locus_tag="JXV47_001053"
     CDS             31663..34254
                     /gene="mprF"
                     /locus_tag="JXV47_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAX1487111.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(34442..35629)
                     /gene="tuf"
                     /locus_tag="JXV47_001054"
     CDS             complement(34442..35629)
                     /gene="tuf"
                     /locus_tag="JXV47_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAX1487112.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            35997..36353
                     /locus_tag="JXV47_001055"
     CDS             35997..36353
                     /locus_tag="JXV47_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAX1487113.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            complement(36594..37598)
                     /locus_tag="JXV47_001056"
     CDS             complement(36594..37598)
                     /locus_tag="JXV47_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HAX1487114.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            37764..38615
                     /locus_tag="JXV47_001057"
     CDS             37764..38615
                     /locus_tag="JXV47_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAX1487115.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            38632..38877
                     /locus_tag="JXV47_001058"
     CDS             38632..38877
                     /locus_tag="JXV47_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487116.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            39064..39768
                     /locus_tag="JXV47_001059"
     CDS             39064..39768
                     /locus_tag="JXV47_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487117.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
BASE COUNT        11302 a         8403 c         6864 g        13465 t
ORIGIN      
        1 attccacatc cagctgacct ttgtcttttt tagtactata ctatttttaa ctaattgtta
       61 tgttcactta cccggttact tttcttttgt gtctgcaaaa ggatctttcg gttaacttca
      121 tcagataatt tcaaaaaagc atccctatct ccatcttcta gtgcttgatc gatttgagca
      181 taaagcattt ttagttttgc ctcttcttct ttttcttgaa aatatcgttc aattaattca
      241 gtatcttctt cactgactga agaatcccaa gaagaaaatg gattgtcttc taagatagat
      301 agatattctc ttgtctgcca agcattttcg aatatacatt ccacatataa aggctttttc
      361 caattcaaac ggatttcatg aaaaatctgg tctgtgtccg taaattcttt tccctgcaaa
      421 aacaatttca tgggttcccc ttcaacagat agatcactga tctgcagtcc tcgatccgca
      481 aaattcgccc cttcaacaaa gtggacattg cttaaaatcg cttcatgatt ggcaagataa
      541 ttcaagatcc aaaaaacttc tcttcggcta aaagatacat gattgaccat ccacgttaaa
      601 aaattcttct tttcccgtac atcaattagc atttttctca cctctctgtt aggtcatcta
      661 ataatgacag tgcctccata tctcctggtt caagtgttaa ataataagtc aataattctt
      721 gcgctctttt cagctgccct tcttctctta agaaaaaggc atactctttc aagaaatctg
      781 gttcatgtga tagttcatga taagcctgtt catagtgtac agctgcaacg gtaaagtctt
      841 ctaattcatt ataagcatgg gctaggttcc attctgcata aggattagca gtttcttcca
      901 tctgattgat cacttgtatc acatcttcat atctttcatc atccaagtaa agattactta
      961 aagtaagtaa tgtttcatct tgtttgtctc ctacttctaa agctttcagt aaaagttctt
     1021 ctgctcgctg tctatcatgc agacggaaag cattttccga ggccaggtga taaagttcga
     1081 cttggtaagg attttctttg attccttctt ctaacactgt ttgtgcttct tcaatcattt
     1141 cttcttcttg aagagcttgt cctagatata gatataacga ttgataatgc ggattaactt
     1201 ctcgaagttc ttccagatag ttgattgcct gctgattttc tttcaattga agattcgtaa
     1261 aagctagctg gaacagtcga tcatctgtcc tttcttcttt cagtgcttct tctaaaggta
     1321 cgatagctgc ttcgaattct ccttgcatac ttaaggattg tcctaaacgt tcctgcatcg
     1381 agattcctga aatttcattt atcccgcttg ccaacaatgt ttcataaacc actgctgcct
     1441 ctttgaaacg atcaactgaa aaatacaatt cagctagcgc aaactggatc aatggttcat
     1501 caggaagcaa cccagctgct tctttcaatt ttgcttcact cacttcaggg attccgataa
     1561 cttggtacaa atcagctatc gccaataagc tttgcggata gtaatcactt tgcttatcca
     1621 ctttttccag gtattcaaaa gctaagtcga tctcattatc ttcgattgca atttctgcta
     1681 acgggatgtt cagtccgtca ttttctgggt attggttgat cagttgttca aaaatctgtt
     1741 ttgcttcgat caaaaagcca atagccagca attcttcgcc tagttcagct aatatatctg
     1801 ctgggtcttc ttttaatgct ttttctaaaa agatttgtgc ttgtgacaag tcttcatctg
     1861 ataaagcttg caacattttt tcgctatttg tattcatttc aattccctct tatctcactg
     1921 acgatttgtt gaaataccgt cattgttctc aataattctt tttcgtttgg atgttggtat
     1981 ccgtctatta tacctatttt ttctaaaaca agtatttttt tgcttttttc tgccaaaaaa
     2041 agaacttttt ccaaatactc catctttgaa atctgttcca gccagtggat tggatagcca
     2101 agcaagtcca gccacacaaa aaagtttttt agttggaaat caaaaggata tgcttggaga
     2161 ttccacacga aatgaaacat cattcctaaa aattttttca tactagcaga aagtagatgg
     2221 ccattttcgg tcagataaaa agcttgttca aacagtttac cataatttga caggttttct
     2281 gcctctaatt gataaaaata gatcatttct tcgatcatcc cggcaaacgg ccgagtcgtt
     2341 aattgctttt tatttggata gtttttatac agattttgca aaaaacgatg atcacaaatc
     2401 attccgcaac agataaaagt caaaaagtca atctgctttc cgtccacctg ccgctcgctg
     2461 attgtttgat cataaacgat gcgttctggc agattgatgg tttgcagcac tacacgattt
     2521 ggtagctgca aaatcgtccg ctgcggtgtt aatgctcggc ttagagaacg gatcgataca
     2581 gggatcatcc atagtgatga atcaagggtt gtatgttttt gaaaaaaacc tgccagatcc
     2641 atgatccctt catttccaaa tccgatgata aacatggatt gattttcggg atagcgtttg
     2701 acgaaatcaa gcaggttctt taattctgtt aaatgattgc attgagtgtt ggcacaaata
     2761 taccagtcat tgtttgcttg atttgcaaat aacgggttga tcttatctgc aaacaaatca
     2821 taatagcgct gattcgttaa aaataagatt ggctgatcaa tggaaagttc tcttagctga
     2881 ctgactagcg tttctccgta aaacactttc gtcaacgcat cttctacttg ataatcaagt
     2941 tccatacgca tccctcctct tcttattttt attttaccat tagtaagcaa attctagaaa
     3001 agataagagc aaagctcacc tcataacttg caaataaata aaaattaaat aaaatacatg
     3061 tgttttctat gtatgacata cggattcgga atctctgtct cttatttatt ccttttctgc
     3121 taggaaataa aaagaaaagc acttgtagcc ctagagccac aagcgctttt tcaactgtct
     3181 tatttaacag cgtcttttaa tgctttacct ggtttgaatg caggtacttt gctagctgga
     3241 atttcgattt cttcaccagt ttgtgggtta cgacctttgc gagctgcgcg ttcgcgaact
     3301 tcaaagttac caaaaccgat taattgaact ttttcgccgt tagctaaagc atcttgaata
     3361 gttgaaaata cagcatctac tgctgcagtt gcatcttttt tagttaaatc agtagctgaa
     3421 gcaacttttt cgattaattc tgctttgttt gccatggata gattcacctc ctccacaaga
     3481 gatatgatag aaatatcatt tagttaaaac tttctgagtg gtccagaagt ttaaaaagaa
     3541 atattgatta acttcaatat tctgttatca cgatatcata tgaaccgctt aatagcaagg
     3601 tttttaccaa ttttcacatg ctttttttag tcatagaaac gtaacaaacg aaactgtctt
     3661 tttcttttga aaaaaaaacg tcgatatggt aaaatgccta ttttctccta cgagggataa
     3721 ttcggatgga cgtcccttca aaagtaaatg cttttctgat ttgattttct aagaaacgtt
     3781 cataagaaaa atgcatcaat tcctcttcat tgacaaaaac gacaaatgta ggtggtttga
     3841 cagcgacttg tgtagcataa aaaatcttca ggcgttttcc tttatctgtt ggtgttggat
     3901 tgattgctac agcatccata atgatatcat tcaacacagc cgaagagata cgaagattct
     3961 ggttcatact tacttgttcg atcatttcag gcagacgttc caaccgttgt ttagtcactg
     4021 cagaaacaaa aacgattgga gcgtaatcaa gataccggaa ttcatcacga atctcttgtt
     4081 cgaaatcacg cattgtattg gtttctttct ttacaagatc ccatttattc acgacgataa
     4141 taattccacg accagcttca tgggcgtaac ccgctactcg cttgtcttgt tcccgaatcc
     4201 cttcttcagc attcagtacc atcaaaacga tatcagaacg gtcaatggca cgcattgcac
     4261 gcatcacgct gtatttttca gtattttcgt atacttttcc gcgtttacgc ataccagctg
     4321 tatctatcat taagaatttc tgaccacttt cagaaacgaa gtgggtgtcg attgcgtctc
     4381 gggtcgttcc ttcaatatcc gaaacaatta cacgttcttc tcctaaaatc gcattgatca
     4441 aagaggattt accaacattt gggcgaccaa tcaaactaaa cttaatcgtg tcgtcgtcct
     4501 cttcttcagt ctcttcagag aaatacttca ctgcttcatc taaaatatca ccaatcccta
     4561 gtccatggct tcctgaaaca ggataaggat cgcctagccc taaggaataa aattcataga
     4621 tatcgtttct catttctgga ttatctactt tattgactgc taaaatcact ggtttattac
     4681 ttctgtataa aattttcgca accatctcat ctgcgtctgt cacgccttcg cgtccgctga
     4741 ctacacaaat gattacatct gcttcttcaa tcgcgatttc tgcttgatgc ttgatctgat
     4801 ccataaaagg ttcatcgcca agatcaattc cgcctgtgtc gatcacgctg aattctcgac
     4861 ctaaccattc accttttgca taaatacgat cacgagttac tccaggagta tcttcgacaa
     4921 tcgagatacg ctcaccagcg atgcggttaa aaatcgtaga cttaccgacg ttcgggcggc
     4981 caacgattgc aattgttgga tttgccatat tatttcctcc tcacaagttt ccaatctcac
     5041 ttagtttaac gaatgcattg ccaactttca agcatagatt gtcaattaaa cgaagtattt
     5101 ttattcctta ttgaaatact aatcgctttt caaaagaaaa actgagacaa aagcagctgc
     5161 tttcatctca gtcacagata caaaatcaat tatttttcag aatcatcggt tgctttttct
     5221 tctacttctt ctttcaacgc atcacctaaa atgtctccca tagtaaatcc agtattttct
     5281 tctggtaatt cataagactc aacatttttt ggttcttctt ctgaagctgg tttttcttct
     5341 aaagctttga tactcaatgc aatacgatgt tcttctggat ggatctctaa tactttcact
     5401 ttcacttcgt caccttcatg aagcacttca tgtggtgtcg caatatgttt atgtgaaatt
     5461 tgagagatat ggactagccc ttctactcca gggaacactt caacaaaggc accgaagctt
     5521 gtcaaacgtt taactgttcc gtctaatact gtgccaactg gagcttttgt atcgatttct
     5581 gaccaaggtc caggctgtgt gtctttgatt gacaaggaaa cacgttcttg ttcaggattg
     5641 atagacaaca ctttgacatt tacatcatca ttgacagcca atacatcact tggttttgct
     5701 acatgactat gtgaaatctc tgagacatgg actagaccgt caattccgcc taggtcgaca
     5761 aatgcgccaa aatcagtaag acgtgcaaca cgtccactga gaacatctcc ctcatggata
     5821 gttgaaagaa tttctttttt cttttcttct ctttcgtttt ccactaccgc tttatgcgat
     5881 aagatcaaac gattttctga tggttcgatt tcgatgattt taaagctcaa tgttttgcct
     5941 ttatagtctg aaaagtctgc aacaaaatga tcttccacca ttgatgcagg gacaaaacca
     6001 cgtacaccga cgtcaacgac taaaccgcct ttgacaacat ttgtaacagg tgcttcgatg
     6061 accttgccct cttggaaatc tctttcgata tcttcccaaa cttttttagc atctaaacgg
     6121 cgttttgaaa gtagatagct gccgttttct ttatctttgc cgatcgtact gataacgact
     6181 aaatctaata catcaccgac ttttactact tcgctgatat cttctaccgg caaagttgat
     6241 aattcttttg ccggaacgac tccttcaact ccagcccctt cgattccgac aatcacttgt
     6301 ttgtcttcaa tgactaaaac ttcgccctta acaacatcgc caacttttac ttcttgtacg
     6361 cttttcattg cgtcttccat tgactggttg ttctcttgat tttgatcaaa ttctgtcata
     6421 acacttgtcc tcctaaccaa cattctgccg taagtacggt actgttttta gtttaattga
     6481 ttattcaaaa aaaataaagc gatttcgttc gttttccttg aaaaaacaat tgtttttcat
     6541 tttttttctt aatttaaaaa agaagataac cttttttcaa aacaacagct tttattgctg
     6601 caacgacttc tggaatcgat ttgccagtcg tatcgatacg aacagcatcc tctgcttgct
     6661 tcagcggaga gacgtccctt gttgaatcat aatggtctct ttcctgtatc tctttcgtca
     6721 gtgtttcaag atcagtcgga attccttttt cttggttctc tttgaaacgt ctttctgcac
     6781 gctcacttac gcttgctact aaaaagattt tcacttctgc attcggtaat acagctgtcc
     6841 cgatgtctct tccgtccatg acaacgccac cgcgttcccc tatttttcgt tggacagcaa
     6901 ctaattcttc tctgactttt ccatgtgcag agacttcaga aacagctttt gtgacatctg
     6961 gttgacggat ttctaaagtc acatcttttg atgctatgaa tacatgctgt ccatcttctt
     7021 gttgcgaaaa agagatagga tactttttga tcagcgaaac tagcccttct tcatctgaaa
     7081 aagatacatt gttcgtaata gctaaataag ttactgcgcg atacatggca ccggtatctg
     7141 tataaatata attcaattct tttgctaata tcttggcaac ggtacttttc ccagatgaag
     7201 caggcccgtc gattgcaata ctgatttgtg tcatgatata actccttttt ctcagaaaaa
     7261 aagccgcaaa gcgcggctat tattatttaa ttcttaattc ttgaccaggg taaagcataa
     7321 agttgtttgg atctaagcca ttcaattcaa acaattgatc agtggtgatc cctgcacgct
     7381 cagccacttg ttttggacct tcgcctgctt gaacagtcgt tgttgaaccg gctgcagctg
     7441 atgaagaagg tgttgtttct gctgcattgc tgcttgaatc ccctgcttga taagttgcct
     7501 cacttgagga agtcggtgtt gtctctgctg caatactgct ttctgacgtt acacctgtat
     7561 cttgagacac agtagattct tccgcgattg tactagattc tactgttgaa gtctcagttg
     7621 actcctcttt tgttgtactt gtagaacttt ctactactga tgtcgaagtt tcagaagaag
     7681 ttgctgctgt tgcattgttg cttgatccat ttctgatcca gaaataagca cctgctggaa
     7741 tagcgataca taagaccagt aaaatcaaaa atagcgaaag aaataatgta tttcctttct
     7801 tttgttgtct ctgagaactt cttgatgaaa cttcatcatc tgtatcgtag attggttgtt
     7861 cccatggttc ttgtgtttcg ttattttctg tagattgatg tctatctttt ctgctcactg
     7921 ttttacctcc taaactctat cgtgtgtatt ataccatagg aaaaagtgtc ttgtcctaaa
     7981 aaatcaatgt tccatgtttt ttttaaataa atttagtaaa atcgttcccc aatgaagttg
     8041 ttcagtctta gaaaaaagct tcctctttgg cagaagttct gcttttgctc catcaatatc
     8101 acaacaattc tgcggctttt cggagagttt ttcgccaaaa taagctaaga tgaattttct
     8161 gcggcagttt tcttcattaa tatagcgaag catctgctgc aggcggaatt ctttttcttt
     8221 ttcctgacgt ttgagccgtt ccacccaatt ttctggtttt tcagactgct ggatcagctc
     8281 catccatttt ttttgcagct catcaaaggg agcttgctct gtggcatatt ccaaataaag
     8341 ctcaaaactt tgtcgctgtt ctctagaaag ttgattaaag aaataatgga tacgttcatc
     8401 cccactttga taaaaaagaa ttgctgcact ttcttcctga tctctgcctg ctcgaccgat
     8461 ttcttgtaca tagttttcta gactgtctgg caaatcataa tggaccacat aacggatatc
     8521 agatttatcg atccccatac caaatgcatt cgtagcaatg agaaactgca gctgattttt
     8581 tacaaactgc tgttgaagtt gtcttctttg agctgcatca agaccaccgt gatagtatcc
     8641 aactgtaaaa cgttccctga ataaatgata caatcgttcg acttcttttt ttgttgcaca
     8701 ataaatgatt gccgctcctt gtgctctttc catgaagtgt tcaagttctt gttctttttg
     8761 ctgcgttttc cgaacaaaaa gcgagatatt ttgccgattg actgattgtc tgatctcttt
     8821 tggtggtcga tcaaatagta catgacgtat atctcttgct actaaatctg ttgctgtcgc
     8881 cgttagtgcc agtgtgaccg ggtttcctaa aagctttcgg atttttccta actgttgata
     8941 ttctggacgg aaatcaactc cccattgaga cacgcaatga gcctcatcta ctacatataa
     9001 cgcaatattt tgttttttca gatgctctaa aagagaagga ttagtcaaca tttcgggact
     9061 caaaaacaaa aatttatatt gcgatagatg acggaggacg tatcttcttt cagattgcga
     9121 aagtaaacta ttgaaagcag ctactcgttt ctcccctcgt ttttgtaatt gcgtcacttg
     9181 atcttccatt agagaaagca gcggtgacac gatgatgacc agaccttcca ttaaataccc
     9241 cgtcaattga tagcaaaggc tttttcccgt tcctgtaggc aaaatagcga gagtatcttc
     9301 tccatcaagc aacgcctgaa taatttcttc ttggccggga cgaaatgaat caaatccaaa
     9361 atattttttt aattcattta ttaacattct gtatcgcttc ctttctcaat agatagattt
     9421 gatacaaacg aaattctcca taatctaatt gtccatctac attccattcg ctaaagcgcc
     9481 actctcgcac ggaatcctta tttggttcca aacgttcgat tgtttctgca gagagaatcc
     9541 actcgtatgg aaaatcatca aaaaacaagg cccactcaat aagatgatct gttactgttc
     9601 ctctttttaa atgacggatt gccatgatct ggtcaattgt ctgaccattc ataaacatct
     9661 gcttggtgat catcatgctt tgattgaaat tttgctgtaa taatgaatcg atcaaagcgt
     9721 gccaaagcga atctggccgt ttttcgattt gtgctaacaa aaggtggata catctgcttt
     9781 gttgcagata aaccgctgac tcatcattgt tttttgccag ctgataagga agcagccctg
     9841 ttcgctcatt tccagataat tggttagcta aaaaatctgc tgcttcttct ggtatctccg
     9901 aaaacagctg caccaaactc tcatacgcag tatcaatcaa aatttcacgt ggcaattggc
     9961 tttcactaag ccattttttt agttggaaag tataaaaagg acttgtctct gctggaagat
    10021 agtcttgaat acccgttgcc agattagaaa ttacttgaac agcaaattta atgagccgcc
    10081 aactagtttc ccctgttctg ccatagcggt caaaacgcaa accagtatgt tctatttgat
    10141 gttcggacaa catatcagcc cctgcaggcg ttagctttgc ttcattttca tttatttcga
    10201 tccaaccttg ctgcgcaatt ttttgcaaaa tttgataaaa cttatcctgc ttcaattctg
    10261 gaaaactgtt atggataaac aaaagttcgt gggtaaatcc ataaataagt actgaagtcg
    10321 ttcgttttcc cacaaggagt tggtaaagag aactaatccg cagcttgtgt cctgatgaaa
    10381 atagcgataa aataaaaaca atcatattat tctccttaag ttaggatggt tagaaatgtc
    10441 actactatgt aaacttgtac ctgaacgctg tattgcatgc ggtctttgtc aaatcgaagc
    10501 gccagatatt ttcgattatg atgaagaagg aatcgtttta tttgcccaag aaccagaggc
    10561 tcatcaacag ttcgtgatgc cggaagaaga aacatatgta aaaaaagcgt atcaaaaatg
    10621 tccagttcga gcgattttat tagaaaataa aatataaata taaacgaaac tttaaaaacg
    10681 tacactaagt tctctaaact tgaaaataag ccgggatctg tttctcttgt tccgtgaaat
    10741 cccgacttat tttgaaagat tcatttgcta tctatagtta attgactagt tttttcacgg
    10801 accctatagg acccatttat attatttcaa ctttttcagc cagttttcca atgtattgac
    10861 gatcacagtt tgctggtctg cgttagaaat ttctgcctct ccatctcctt tttgctcacc
    10921 atagctgcca aaacctccat gatttccgcc attgattgat acatactctg ttctttccgg
    10981 taaatactgc ttagcttctt gataagcttc ctgattcaat actttatctt ttgtcgccgt
    11041 gatcgataaa acaggaacag ctgattctgt caatgttcct tttttgtcgg gataacttgc
    11101 catgaagaat acccctttta aatgtttgtc tgaatgattc ttattgacat aacgacttgc
    11161 cattacgcca cctaatgaat ggccaccgat cacataatcg gaatttggaa aatcttcttt
    11221 gaccttatcc gctttgtttc cgcccatcac tgctagatca agtggcattt tgacaatagc
    11281 gactgaaaag ccgttttttg ctaaatcttg cgcccaaata ctataacttt ctggctctac
    11341 gagagcacca ggataaaaaa taagtaatgg agactttcca tgattctttt tctctccttc
    11401 aaaaaataag taatcttctt tgttttttcc ttcttttacc aacacttgcg cttctgacga
    11461 tggttcgtac gtattttgct gtatatagta ataaccggct ccaccgagta atcctaaaat
    11521 gatgactaag ccaattagta ttcgtctaaa tattttcact ttctcccacc ttttctatct
    11581 gagtgacccc tttttcttaa tcaagtatga ttatacctta aaaaaataag agagaaatgc
    11641 aaactttcca gcatcaaata aaaaaagacg gaatatccat ttgaatatcc gccctttttg
    11701 tatgtttatt tttatttagc acataaacga tacacagctt ctgcataaat ttccattgct
    11761 ttatacatac tacttaattc ccatcgttca ttcgcctggt gcataaagtc aggagtatca
    11821 gggaacatcg caccgaatgc cacacactgg ttcatcgtac gagcaaaagt agcgccgcct
    11881 gatacaaacg gttcagtcat gtctccagta atatcgcgat atgtccccaa tagatttttc
    11941 actaactcac tgtctagtgg cacgtataat gaatcaagga agtcaaattc ttcataagtc
    12001 aacccatatt tttctgctgt tttagttaat ttagctacta aatcatcttt cttgaatgta
    12061 acagggattc tcatatctac accgattttt gtttgttctg gtgtgatttc caaacttgca
    12121 aagttcatcg ttagctcgcc ggattgttca tcttctgttt tgcccacgac agcttcacca
    12181 gttgcatttt cttgaactaa ttttcctaag aaattgattg ggccaaaatc aaatacttct
    12241 gaaagagcaa ttgccagacg agaaatagca ttcactcctt gtgctgcatc tttcgcgtgg
    12301 atacttttac caagaacgac gatgccttca ccttgttctt cgaaatcgaa ttcgtgtttt
    12361 ttcaatgctt cttttacttc agaaagcttt tctccagagt aaggagctgc atcaggaaca
    12421 acattcaacg ctcctccagc ttttacagaa aactcgttcg ttcctggtcc tgtcaagtaa
    12481 gcttgcaata agcctttttc tgcataaatt aaaggaaatt cagcatctgg cgcaaatcct
    12541 tgcgtaattc cttcttcttt ttcgttatat ttttctaaac aacgccataa attttcttca
    12601 tctgtaccaa agataaaacg aatacgtgtc ttgaattcca cgccagcatc aatcaaagct
    12661 ttgacggcat acattgccgc aatagaagga cctttgtcat cttgggatcc gcgaccaact
    12721 aaccagccgt cttttatagt tggatcgaat ggttttgttt cccaattatt ttcgtcccct
    12781 gctggaacaa cgtccatatg acacaagata ccgaataatt catctccaga gccaatctct
    12841 gaataaccgt aatagccttc tggatcttta aatgttctaa atcctagctt ttcactgatt
    12901 tccaatactt tatccaaagc ttcaatcact tttttaccga agggatgtcc ttgtcctgaa
    12961 tctgcttcat ctagtacgga aggaattcgg atcaattcgc tcaatgattc taatgcttgt
    13021 tcatgatgtt gttctgtcac aaattttttc atgatattat cctcctaata tgttaaaaag
    13081 ggtcatgtca aattcctccg acacaacctc ttcttctcaa ataatgacgt tttaagcctg
    13141 ctccatcagc aagcagaatg ttcttaacaa atgatgaaag aaaaaacact cactgaatgg
    13201 agctattgac ttatccacgt gcttatcgat agccgtttat cggtttcttc attcttatga
    13261 tagaccttgt acctgtattt gtctaggttt agaacattgc tgctacacct aggatcacac
    13321 agatggctac aaataatatc gcaattaatt taccggtaaa tttccaccac actgaaacat
    13381 cgaaacgagc aattgctaca gcacccatta cgatagcaga tgttggtgta attaagttta
    13441 ctaaaccaga tgcagattga taagcagtga ttactaaatc cttaccgacg ccggcaaatt
    13501 cacccatagg tcccatgatt cccattgttg cagcagctaa gccggaagtt gaaggaatca
    13561 agaatgacat agggatatag aaaataaatg taataatgat gaatacactt gaagataatg
    13621 aacttaatcc ttgttcgccc caatgtaaga tggtgtctgt gattaatcca ttgttcataa
    13681 ccacttggat accacgagca acagctacta cgattgctac accgatcaaa tcagaagcac
    13741 cagctaaaaa ttcagagaca aattcagact ctttcatgcc ataagtgatt gctactacga
    13801 tggacattac taagaataac atagtaattt ctgggaagta ccagtcacct aatggaagca
    13861 tgcttttacc tagaaccgta cctagtaccg gaaggtttgt taaccagttt gtcaatgatt
    13921 caaaaatcgt gaaattcgca ttcaaggttg tccaaggaat caaactgatg atcatgatac
    13981 caaaagtaat aaagaacaat acattaacat gtttttgttt tttcgtgatt acttcttgac
    14041 gaccgattgc ttcaatatcg aaatgcttca tatcttcttt acgttggttg tatactaatg
    14101 attttgttgg atctttttcg atctttgatg cataacgata cacatataca atagaaatag
    14161 ctaacaaaat aacgaacatc aagaatcgaa gaccaatacc ttcacccatc gaaatcccaa
    14221 cagcttgtga agctacgcct gttgcaaaag gatttaccgt tgaagctaga cagcctactt
    14281 gagaccctac taatacgatt gctacagcta ctactgtatc aaagcctaca gccatcatga
    14341 ctgggatcag taaagcatag aatggaatcg tttcttctgc cattccgtaa gtagagccgc
    14401 ctaatgcaaa taacagcatc aatactggaa taagcatttt ttcttttcct ttgaatttct
    14461 tcacaactga agcaatcccg gcatctagtg cccctgtttt gttgataata cctaaaaatc
    14521 caccaacaac caaaatgaag aaagagattg ggattgcagc aggtgtttct ttagttagct
    14581 cccccgctgg tacacctagc atcccattga ttggcgccat gaaaatatcc cacagccctt
    14641 gaggattttg ttgtactcgt tcatatgatc cagcgacgat gttgcctgca tcgtctacac
    14701 tatagtgccc agctggtata aaccaagtaa gtacagcgat tactgcaata ataataaata
    14761 agaccgtata cgctgaaggc atttgaaatt ttttcttttt tgtttgttcc atcttcttct
    14821 tcctttcttt tccgttagag acaacaattt tggctctaat gttattttat caaaaagagt
    14881 atcagaacaa aaataataac acgcattttg taaaactttt gttcaaaaag ttcgtttttc
    14941 cctattccct cctctttttt caggttttta aagctttctt ctttttcatt gtagcgtttc
    15001 ctttttttta taaacaaaca ttttcgtctt ttaaaaggag aagaatttca catttgcaaa
    15061 gaattgattg atttttatgc ataaatcaaa aaaatactca aaacaaacaa ataaaacgtt
    15121 tacattattg catgtcttgt atttttttcc aaaaaaaaag accaagaaat ttcttgatct
    15181 ttttgatatt tatttgactg ctgtatgacg ttgttcgaac tgatgttgtt ttcgacttaa
    15241 ccatggaaga agttgcgcat gcagcactaa aaagacagca ctcacgatga atcctttgat
    15301 caagttgaaa ggaacgatcc caatcagtac atagtttgct aaagacatgc ccagcatctg
    15361 tgttgcgttc agccctaaaa acattaagta aagaggcgta ataacgaaat aatttgcgat
    15421 actcataaaa atagttagag cgatggttcc tgtaatgaca cctaaaaatt tgtttcttcc
    15481 tttatgctgt ttctttacac taaagaaata ataaatcggg aatgtaaaga tcgttgttga
    15541 taagaaacta gcagtgtctc ctaccaaatt atccggagaa aaacctgtag tcagcagatg
    15601 taatactgaa cgcaagaacg ctgttgcaac tccggccgct ggaccgaata agaacatgct
    15661 gatcaatacc gagatatcac taaaatcgat cttcaaaaaa ctaaaagccg gcatgatcgg
    15721 aaaagcaaaa tactgtaaaa ctaatgcgat cgcagcaaac atcgctactg caaccatttt
    15781 ctgtacacgg gtgttcttca tttgaaatcc tcctgttagg actcctcttc agcgaacttt
    15841 ttgacgtttc tctccaaatg aaaaaactct attttccagg gaaaatagag ttagagttat
    15901 ttgatcaagc gtcgtcaaat aagctctatc ttctttatcc agactatact gtcggtatcg
    15961 gaatttcacc gattcagcta tttttttgca aaataggtcg tggactataa ccaccggtcg
    16021 ggaatttcac cctgcccctg aagacgaacc ttatataatt tttgtttaca tattcattat
    16081 acatatctat tcaaaaaacg caacatctaa cacttataaa aagtaagtgt tcattttgag
    16141 tggttcagca aactgctgac ttcttttttg ttcagttcac ggtaatcccc aggacgtagg
    16201 ccttgtaaag tcagatctcc gtatttttca cgttttagtt tttgcacagg aagaccaact
    16261 gcttgaagca tatttttcac ttgatgatta cgtccttcgt ggatcgtcaa ttccacgata
    16321 ctgtggtttg tcttaggatc cactgataaa atttggaatt tagctggaga tgtttttcgt
    16381 ccttcgatct ttattccttt tgtcaaaggt gcaagcatcg attttgtagc gatccctttt
    16441 acctttgcaa cgtaaacttt atccacttca tgttttggat gtgtcaggcg ctgagcaaaa
    16501 tctccatcat ttgtcagtag caagatcccc gaagtatcgt aatccagtcg acctacagga
    16561 tagatacgtt cttttaccat cggcaaaaga tccgtaacaa cttttcttcc tttgtcatct
    16621 gcaacagcag aaataactcc tttaggtttg tacaataaat agtaaccgta ttcttcttga
    16681 taaattggga cttcatccac ttccacagtg tcatgtttcc caacttttat ccctaattcc
    16741 cttacaactt gtccgtttac ttttacacgt cctgcaagga tgaattcttc tgcttttcga
    16801 cgagaagtga tgccagcgtg ggcaattact ttctgcaatc tctccattac aattattctc
    16861 ctttattcat tccatcaaag aatagatctg gtgacacgtc ttcttcaagt gaaatttcca
    16921 tttcttgtgt atcaggcagt tcttctaatg atttcaaacc aaaataatct aagaagtagc
    16981 cagttgttcc atataatatc ggccgacctg gtccttctac tctacctttt tcttcaatca
    17041 gtttatgggc agctagacgc tgtaccgctc ctgaaacctg aactcctcga atctgctcga
    17101 tttcagctct tgtgattggc tgtttataag cgatgattgc taaggtttcg acggcggctt
    17161 gagataatgt gtttgatgtc ccttgcgcat atcgcttaag taagggagcc agctcttttt
    17221 tagtcgttaa tacataatgg ctttccgttt caaaaatatg caaagctgag tgcgagtttt
    17281 gagtgtaaga ttcttttaat tctttcacta aacttgtgac ttctgcttcg ctgagattta
    17341 acagtccgct taattcttca ttactgatcc cttcctcgcc aacaataaaa agaagggctt
    17401 caagttcact taatttcgtc atgttcggta tctcctactg ctggataaag cataattgat
    17461 tcatagtttt ctttttgttg cgcaatgatc tgcccttttt tcatcaattc tagcaaagcc
    17521 ataaaagtag tgacaacttc acttttagaa ggtgactcaa aaaaagaatc gaaagtacag
    17581 ccatgcgcat ttctttttat acgctcttcg ataaatacca ttcgttcttc gatcgttgtg
    17641 tcatcgggcg tgatcgtttt ttccactttt tgagaaaatt tcttacgttc taagattttc
    17701 tgcatggcac ggatcaaatc gatttttttg acttgtcctc gcttcaacgg cttttcagca
    17761 tccgctaacc catcgatgtt cataggttct tttgtgtaat aaagacttcg ttcctctgct
    17821 ttttctgtca gtctttcagc tgcatattta tatttacggt attctaaaag ctgagtgacc
    17881 aattcttctc gaggatcttc ttcccataat tcttcatcgt ctgtgacgaa ttcttggaca
    17941 ggaagcaatg tcttgctttt gattgccatc aatgtagcag ccatcactaa gtattctcct
    18001 gcaacagcta gctcgagtgt tttcattgta tggatataat tcatatattg ctccgtgatc
    18061 gtagcgatcg gtatatcata tatatcgatt tccatttgct gaatcagatg aagcagcaga
    18121 tcgagaggac cctcgaatac atctaattta atattgatct ccgtcaactc attcactctt
    18181 tcttcttttt ctttgctagc cattttccaa tgtaaggctc tgtgatttca gttgcacgga
    18241 tggagacatc cgggtacttt tcctgtaatt catctaacat ttgaaagccc atattctcac
    18301 cgcgataaga cggattcaaa gaaatgtcat ggatgatcag ctgatcgttc gttgcccagt
    18361 aaataccaat aatcccttga atgttggttg aaccttctgg cgtaaagaaa aaaagttcat
    18421 aatcgtcttc agattcgtac gtatcaatct ccttcaacaa agaagtttta cctgtcagtt
    18481 tcttatggaa actcaatagt cccatagcaa ttttacggtt ttctttccgg taatgtgtta
    18541 acatcttctc accttcctat gactaagccc ttggaaaatg ctgcttataa acatccgtca
    18601 ttcttttctt cgtgatatgt gtataaatct gagtcgtaga gatatccgcg tgacctaaca
    18661 attcctgtac tgtccgcaaa tcagctccat tttctagcag atgtgtggca aagctatgcc
    18721 gcagcgtatg tggtgttact tctttgtaaa tcccagcctc tcgtactaac tgcttcagat
    18781 ttttccagat tccttgccga gaaagacctt tcccatgatt attgacaaat acatgcattt
    18841 cagatgcgtc ctttacaagt aatggacgtg cttcgtctaa gtagcgttcc agccattgga
    18901 tcgcataatc acctaaagga atgatccgct ctttatctcc ttttccaact gtctgtacca
    18961 gtccaagaga aagatgaaga tctcccaatt tcaatccaat caattcactg acgcgcatcc
    19021 cagtagcata catgacttcc aagattgcac gatctcttat ccctaacgtt tttgtcgtat
    19081 caggtgcttc aatcagcttt tctacttctg tcagagtcaa tgtacttggt aatttctgtg
    19141 ctttcttcgg cgtatcgata tgttgcatcg gatcatgatc agtgatacgc tcttgccgta
    19201 aaaactgatg gaatcttctg agacttgaga tcatccgagt aacagttgct gtcgcttttt
    19261 tttcttcatg caacttctcc agaaaacgga tgactaaaaa gcgatcgaca tcctgccatg
    19321 aagcaatttt ctgctcctgt agaaaatgca agtactgttc caaatcacgt tcatagcttt
    19381 gtcgtgtatt ggcggacaat ccccgttcaa tattcaagta gtggagataa tcgttgattt
    19441 gctctttcat aataatcccc ctcatgcctc tctatcatat cagataccgc ttcattctga
    19501 tagtcttttt ccataatctg agcaaagaaa aagccgtcta gacactcaga cggactggtt
    19561 tcttttttct ttttcatagc attcctgaca gattccatgg aacgttagcc gatgatcttt
    19621 tactaaaaaa tgataacgtt cttctactac ttgctccact tcaagtaaaa gatcctcttc
    19681 tacttcctcg atcgtgccgc agttcaagca tagtaaatga tgatggaaat gtttggcgcc
    19741 ttcttttctc aaatcataac gggctaatcc atcattaaaa cttactttat cgacaatttt
    19801 caattctgtc aagatttcaa gggttcgata aacagtagca agtccaattt ccggactctt
    19861 ttttttcact aaaaagaaga tttcttctgc agataaatgc tctttctcat tttccaaaag
    19921 cacaagcaga gtagcttctc tttgcggtgt cagcttaaac cccgcttcat gtagctgctg
    19981 ttttgttttt ttcatcgccg aaatagcatt catgaccatt tactcaaccc caacaattta
    20041 taataattac aaataaaaaa agatataaca ctatgttaat taaaattatt ataagctagt
    20101 taagaaaaac atgcaaggga ttctcaatta gattttttga ctagttttgt cacaccgttt
    20161 tcttgtgtaa tcaatccttg tttcaaaaga ttacctaatg cgcgcttaaa tgctcctttg
    20221 ctgataccaa aagctttcat gatttcttct ggatccgatt tatctgtaaa gttgatttgc
    20281 tgatctgcag aacgttctaa aatggttaaa atcatttgtg catcatctga tatagcttca
    20341 tatgctcttg gcttcaatga aagattcagt acaccgtctg gtcggacacc aatcactcga
    20401 ccttttatct gctcgcctag acgaggttca ttatatcgtt cagaaggatg gataaaccca
    20461 agatagaaat cttccgttaa aacgtacgta cctgttaatt tcaagcggta tgctgttcct
    20521 atcacatctt tgtttttcat ttcttctgtt ccatatttgc ttaaagattt gaatattttt
    20581 tcatctgcta aactgcccca aatacggtct tttgcatcaa ctctaaggga aatcatcaag
    20641 cgatcccctt ttttaggcca tagctctgtc attgtcggca attcatcaag agatacgaca
    20701 aagtctttat ctggaagacc gatatcgaca aacgcaccta aatcttttcg tgtagcagta
    20761 acgattccaa aagcgtaatg accgatacgg cttttaggaa tttgtgtagt gatccgattt
    20821 tcatgttttt gattttggta accgaatcct tcaactgctt caccgatttt gtgttcacct
    20881 tctgatttgc ttaagccaaa ggtttgtccg tttttttgga caaagtagtt tttttcattt
    20941 tcatcaataa taatacctgt aaatatagtt gctaataaat cgttcatttt tttctccctc
    21001 tatagtgaaa ggttttctta atacatttct ttgctatcat aacataatgt tatctacttg
    21061 aatagctgag ccttggtttg gaaaggtgaa aaaaggagta tgacaacagt tgtgtcatac
    21121 tccccttttt cgaataaacg gtgttaaacg gcaggctcac agcctctttc atttgcctaa
    21181 aattaattgc tcccatttcc tccgaaccat ccagttttac agttgatggt tacgatgtaa
    21241 aatggcaaag cactttctcc aatgcctttc atcaatgcag attttgttga agtggcatat
    21301 agattataat agccttcccc attttcgatt ctggcttttt ctaatctgta acctccttca
    21361 acgatatatc cacgttggat acatgtagca atcactttgc tttggacacc tggtgcccac
    21421 gtccatgctg gattagatgc atcggcaata tcacttgctc tggcagattt gattggctga
    21481 ttcgctgagt ttgaagagga aggggtcgag gatgccgctt cttgctgtgc tgcttgtgcg
    21541 accgcagctt gttgagcggc ttgagctgca gctgctgctt gagcggcttg ttttgcttgt
    21601 tcttcagctg cttttttcgc ttcttctgct tttttctttt cctcttcttc ttttttctct
    21661 ttatcagtga gcatcttatc tacttgtttc aattgttcat tcaactgagc agatagatct
    21721 gtatttttca ctttttctac tgcttctttt gccgtcttgt attggtcgcg tgttgctgaa
    21781 tccactactt ttccgtcttt aaagactata gctgtttttt ctttagctgt ttgcaattca
    21841 gcatattgat ttttagcttc tgtttgtgct tgttgaatca attttccaaa atctgtgtta
    21901 tccgtttcga ttgcttggat ctctttatct gctttcaact tgatgtcatc tgctagatga
    21961 tcatcgacga tggcaggtgc tatgaaccac tcattcactt tttggatatc tcggatctta
    22021 gattggatat cttggtaagt tgtttctaac tctgaatatc ctttttcatt cttaagactg
    22081 gataaatcat tttttagttt tgataaatct tgatgaatca tatctgcacg aataaattga
    22141 tggtgatcat ctgtataaaa ggcagcaagt ttctcatgaa gttcttccat ttgttgctgt
    22201 ctttttgctt ctgctgctac ttcggcttct actttttgat gatggtcata ataagcccag
    22261 cttcctccac cgagtagaag tactgctgct aaaacgagat aaggtacttt ttttgatttt
    22321 ttcttttgcg ctttatctgg atctgttttt tctaagtttg attcttgatg tgttttttca
    22381 gtatctggca cgattgttat tgatttcgct tctgcttcaa acagcttagg ctggttctct
    22441 tctttttcta tttttgcttc aagatcagta ccctctttgc ttacagattg attttcagca
    22501 tcggattcac tatttatttc atcgggctct gttgactttt tgtctgtgtt ttcgagtatt
    22561 tcttttttct ctgcttccgg cagtttattc gttttttcct tttctaattg tttttcagta
    22621 aatacttcag ttttttctgt gatatccgtt tttacgtctt ttatttttac tgtttcttta
    22681 cctgtggcgt tttctctatc agagtctttt tcagtttctt gttccttttc tggctctact
    22741 ttgttttcct gtgcaatttt ttcactgatc attttgagca gctctttcgc gtgctcttct
    22801 tttgtatctt cacgatgtgc tttgatataa gcggatagta tcgaattttc ttcctcatta
    22861 tcgacgattt ctttcagttc agctactctt cttttttgtt ttgattcaag cgtttcttct
    22921 tgattctttc ctgattcttc cgaagtctca tgaacagttg ctttcttctg ttcatttttc
    22981 tctatattag ttacttgatc gtgagcaggt ggttcttcgt cttctggttc tgctttttcg
    23041 aataattcca ttacagattc tagaggtaaa tctttcaatt ccgaccattc gattggatcg
    23101 tttaattctg tatcaggaaa gactgcatct tcagttgatt tatcctgcat agctgcatct
    23161 gtatttgttt cttcaattga ttcttttatt tgctgatctt ctgcagttat ttgatgaccg
    23221 cagtctggac agatagtatt ctgctccatt tttttcgatc cgcaatttgg acattttttc
    23281 atcacttagc gatcggctcc tttactaggt ttacgctacc atttaatcta tcatattcta
    23341 tacgtcacgc caatagctta tttttaggat ttacttaaaa ataatgaatg aatttccttc
    23401 ctatagaaaa aaaagcttga gactgcgtag tctcaagctt tttttctttt aaaataaacc
    23461 aaacagtttt actgatttct cttctggtca atagtccacg cttattctaa gaaatctttt
    23521 aattgttttg aacgagaagg atggcgcaat tttcttaatg ctttagcctc gatctgacga
    23581 atacgttccc gagtaacacc aaatactttc cctacttctt ccaatgttct cgtccggcca
    23641 tcatctaaac caaaacgtaa gcgaaggaca ttctcttccc gatcagtcaa tgtatctagt
    23701 acatcttcca attgttcttt tagtaactca taagctgcgt gttctgctgg acttgttgct
    23761 tcctggtctt ctatgaaatc acctaagtga gagtcatctt cttcaccgat tggcgtttca
    23821 agggaaacag gttcttgcgc gattttcaag atttctcgga ctttttctgt tggaagatcc
    23881 atttccgcac cgatttcttc tggcgtaggt tctcttccaa ggtcttgcag caattgacgt
    23941 tggatacgta tcaatttatt aattgtttca accatatgaa ctggaatacg gatcgtacgt
    24001 gcttggtcag cgattgctcg agtgatggct tgacgaatcc accatgtagc ataggttgaa
    24061 aacttaaatc ctttgcggta gtcaaatttt tcaactgcct tcatcagtcc catgtttcct
    24121 tcttggatca agtcaaggaa ctgcatgcct cgtcctacat aacgtttagc gatacttact
    24181 actaaacgaa ggtttgcttc tgccagacgc tgtttcgctt cttggtcgcc ttcttcgatt
    24241 ttcaatgcta acgctacttc ttcttccgca gttaaaaggg agacacggcc aatttctttc
    24301 agatacatac gaaccgggtc attgattttt acaccggttg gcgcagaaag atcttctgtt
    24361 tttgcttgtt cagctttttt ctcagcactc ttcaagctgt gaattgatgg atcaccattt
    24421 tcatccacca cactgatacc tgcgtcttca atcttttgga tcaatttgtc catttcatct
    24481 gcattcaaag tgaatggtgt agcaagctga ttggataaat catcatatac aacttgtcgt
    24541 ttgggtttgt tttctttgat gaaagctgct actgctgctt catacgtttt tttatctgtt
    24601 ccatttgcca taaaagaagg ccccccttga gtagctattt ggcttgtttt aactgtttcg
    24661 ttaaattgat gatttcaatc gtcaattcaa gctcaagctg tttgtttcca gttcgtctgg
    24721 cttcttgctg catttgtttt tttaatgtta tttcatcagc taagccagat ttgctgatca
    24781 catctagcaa gtcttggatt tctcgtggcg aactttcttc tgccaccggt aaatattcga
    24841 tttccaccac caaccgcctt aaattttcat cttgcaaaaa gtctaaaaac tctgcaaggt
    24901 tgaattcata atgttgtgag acatatgcat cgaataaaaa ataaacttct gcatatgcat
    24961 catgaataaa ctgaaattct cgttctttta aaatattacg gacagaaact tctttaaatg
    25021 cacgatataa tagaatctgc tctgcctttt ctacttgcgt caaaggtctc tttttccgtg
    25081 cagtttcttg tctcgtaacc tgagtgtgtt gactttcctg aggttcttga cgattttgct
    25141 gatttgtcct tcgaagatcg cgcagttgtt tttgtatcgt ctctctgccg atctgaaact
    25201 ctgttgacag ttgagataga tacatatctt gttcgattgg tgaaacaact cggctaagtt
    25261 caactagtaa ttcttcgagg tattcgatct tgtctttttc attatctaaa tttttccctt
    25321 gttttaaata acgtgattta aaagtaaaga ctgtttcgcg cccatgagcc actaattctt
    25381 ggaaagatgc ttctccatac ttacggagat attcatcagg atcaagcttt tctggaacga
    25441 ctacgacaga aagtgctaat cgactgtttt gccgaagcaa ttcaatccct cgattggttg
    25501 cttcaaaacc tgcgttgtct ccgtcatagc aaaagaccaa ttctttcgtc agcttttcca
    25561 tttgttggat ctgttgagct gttagacttg tccccataga agctaatcca gttttgatac
    25621 cagcctgcca tgcagcaatc acatccataa acccttcgaa caacaaaatt tctccgtttt
    25681 tccggatatc gcttcttgct ttatcaagat taaataaaac ttgtctttta ttgaacagtt
    25741 ctgtttctgg actattcaag tatttgggct gatctttttc ctgccctttt tcaggtgcaa
    25801 gccagcgtcc tgaaaaaccg atcgtctggc cttgagaatt acgaagtgga aacatcactc
    25861 tttgataaaa acgatcagac atacggccat catcatgcgt gacaaacaat ccagagcgtt
    25921 ctaacaattc atttgaaatt gattcattct tgaatacttg ctgaagaaaa gaacgctcat
    25981 taggtgcaaa acctatgttg aattcttcaa ttaattctaa agacaaccca cgactttgca
    26041 aatattctaa agctggctgt ccagcttttg tatgcaatag catgtgatga tagatttccg
    26101 ctgctttttc atgagcagca atcagtttcc ccgtagcaga ttcaggattt tggacagcta
    26161 tagtacgctg acgccattga tcttctaacg gtatctgttc gaagtctgcc acttttacca
    26221 ctgcttctgg aaaacttaga ccttctagtt cttgaagaaa agtaaacacg tttccgcctt
    26281 taccacaacc aaagcaatga aaaatctgct tgtcttctgc aacagaaaaa gacggtgtac
    26341 gttcttcatg aaaaggacac agccccaagt aatttttacc agactttttc aactggacat
    26401 attgtccaat cacctcaacg atattcgttt gactgcgtac tgtttcgata acctcttgag
    26461 gaatccgttg agccattttt tcaccccctg ctctattgat atcttttggg tttaacagaa
    26521 gatatttcag gagaataacc ggtaaaaaat cgcactaact gaaatcagtg cgattttaaa
    26581 ggacacaatt atacatgttt gattgtatca tatttcattg ctttttcaag tataacacat
    26641 ttctatctca ttaagcatca atttgctact cttttcagta actgattttg aatatcagcc
    26701 ttccagtaca atactcgaag aacaatattt acgagcatga atacaaagaa gtatcctacg
    26761 ctctctccca accctaagtt tacttccaaa attccatgga acagcattgc agctacatat
    26821 atccctacga tcgtcgttac tgctaggaag atgcgcaatg ggttgaaggg ataacaagct
    26881 tttacaactg ccatgcaact gatcccaatc agcaagtaat acatcaaagt agtagtttca
    26941 gcatttcccc atgcgaatgt ttttccaagt agatacaccg caatgatatt cactactaca
    27001 agcaaggcat ttggtaaagc attaataagt gctgtaggca aataacggta agtgattttt
    27061 cttttatctt gttcaaaaga taaaaagaag gaaggatacc cttcaatcgc taaatcaatc
    27121 agcgtgattt ggatagggat aaacggaaat ccaattgctg taacggcaca tataatcgat
    27181 aaaataaatg aataaatcgt tttgataaaa aagatgcctg agactttcgt cacattgttg
    27241 accactcggc gtccttcaaa caggacttct ggcaatgtag taaaatcaga gtccaacaat
    27301 accagattcg caatctgacg tgttgctcca tcaccttctg ccatagcaat gctgcaatct
    27361 gcttctctta acgccaaaac atcattcaca ccgtcgcctg tcattgcaac cgttctgccg
    27421 ctttctttca attcatttac cagcaatttc ttttgctgcg gactcactcg tccaaaaacc
    27481 gtatagcgat gagcagcttc tcgcacttcc atttcttcag taatttgaga aagatcgaca
    27541 tacgcatcat aattcggtaa tcctgcacgt ctagcgatat tggagacagt aaaaggattg
    27601 tctccagaaa tcactttcag atccacacct tcctcatgaa gataagctag tgtttcttga
    27661 gcgttttttc ggattggatc atcgatttca aacagagcaa ccggctcaac aaatgctggt
    27721 ttttcttcgt tcaattgctg atttggagcg atccccaaca taagtacgcg atagccattc
    27781 gcttgggctg tttttagact gtccggaagc cgatcttctt ccaccaaacg ttcaggcgct
    27841 cctacgtaca cgactcccag ttctggaaat tccatcgcgc cccatttgcg atcagaagaa
    27901 aatgcgactt tgtttgtcac atcataccga ttagaaagct caaaataatc tctcatagcc
    27961 cgcatagtga tgttgttatc actgctttct gccagatacg tccccataat ttctgggatg
    28021 gctttctcgt acagcggatg tagtgcttct acccgctgga tactcatttt cccttcagta
    28081 atggtccctg ttttatccaa gcataatgta tcgacatggg ccagcgtttc aattgaatac
    28141 atgtcttgaa caaggattcg tttttttgcc agtttggtta cccctgtcgt taatgcaata
    28201 cttattagca ataccaaacc ctttggaagc atgcctaaca aagctgctgc agatgcaata
    28261 acagaaattt tgatagaagc atcgcggatg aacagtgctt ccaaaaatag tatgatcccc
    28321 aaaggaataa tcacgaaact agtgaatttg gatactttgc gaatcgaatc tacaagttca
    28381 gaacgaatag ctttgtgagt ctttgcctcg ctagtcaagc ggacagcata attatctgca
    28441 cctactcgga taacttcagc catgacagaa ccgcttgtca aaaagcttcc agaaagcaat
    28501 tcagctccag tttctttgac aatcaaatca gattcgcctg tcaaaagagc ttcatttgct
    28561 tctgcccgtc cagatataac ctgtaaatcg gctggtatct gttctcctgc tccgattttt
    28621 accaaatctc ctaataccag ctctttagta gaaatcgatt gttctttacc gtcccggatc
    28681 actagtactt ctgattggga aacaatcgat aatttccgta caagatttct tgcatgtatt
    28741 tcttgataaa ttccaataac gatattgacg acaataattg ctaaatacgc catgttggaa
    28801 tacgcaccta caaataacag acaaatccca ataccaaagt tcagaaaatt gaataacgtc
    28861 aatatattat cgctgaatat ttgttttgta ctttttgatg catcttcctg gtagtcattt
    28921 tgctggccag aagccatttt ctgaactacc tcttgctgtg taagtccatt cattttcttt
    28981 ttctccattt tccgccaact ttcaaaaata atcacgtgtt taagtctagc gtgttccaag
    29041 attaaaaaca acttgttttt ataaaattta tagaaaaaca cacgaatgat tttacaaaaa
    29101 agatgccaac ctttttgttt gaatcacccg tgtgctgttt ttattatcaa tctatcttta
    29161 cttatattgt tcctccaaac ggctcatcca ccaacctagt gctgtaccgg ctataaaaag
    29221 aacaggacaa gctagtaccc cagcaactcc caatcccgcg taatcggtag gaatgatcat
    29281 aatcgttgaa gcaaaaacta cacctaaaat gaaatggaat agcttgctat atgcctttga
    29341 gaaaatgtaa tccatgattt ttgacaatcc aagaacacaa agaatcccac caattccgat
    29401 cggcacaatc acttcaagtc gtacttcttt aaatccgtca gccatcgctt tatacaatcc
    29461 catatacacc aaaaaattag aagggctcaa tcctgggacg atcataccca aaccaatcaa
    29521 tccgccggca atcagccatg ttccaaaatt ctgatcgact tgcccgtcaa ataattgagc
    29581 gccgtataat aaaaacaaat aagccagaac aaaagtaaca accatgatga tcacatcaga
    29641 agtatctctt ccttttttcc ctgcttcttt ccataacgca ggaacagttc cagcgataca
    29701 tccgacaaaa aaccataata tcgttgtttc atacgcacct aataaaaaac tgactaaaaa
    29761 agaaagtaga aagatgcctg tcactccgcc tagaccaaca ggcagaaaaa acaaaacatt
    29821 ttctttgaaa ttttttgtaa ggtgggctaa aaaagaaatc agccgctcat acatgccaaa
    29881 gacagctgct aatgcaccac cgctgactcc tggcaagata aatcctgaac cgataaacat
    29941 tcccttcaca aaccgtaaca tccagtcttt ggttgtgtac cccacttctt gattttccat
    30001 tttttgcctt ttttccacta tttgcgtact ccttctttca tttaatttta ttcatgattg
    30061 aacatttcct gctattttac ttaaagactt tttcataggt ctctattatt ttttcattca
    30121 ttttgacaat atcaggataa aacatgttac ctccattatg atagagatag ccgccattgt
    30181 aaagcaagga ctggatccgc caatatcggt attgtttccc ttcctcattt cctaaaagtg
    30241 ggctcagcac atctttagaa tacgcttctg ctaattctac tgtgttttct ccgccatgat
    30301 tttttacata ggcaatataa tctttcccaa aattatatgc ttggacagct gtccataaat
    30361 cgcatccttg tttctttgct tctactatca tttccgccaa atatttgaca ccttgatcaa
    30421 tactgtcagc tggattatca atgatctcag cttctccatg cagactttcc gagctctgca
    30481 tgagatctgt cccttttcct tttgattcgg tcaatattat cgccttgatc aaattctcgt
    30541 agttttccat atgataattt tttgcagctg ttgttatttc tatttgatag ctttccactc
    30601 gttttaccga acgataagtt cttcctcata aaaacaacac cgcaccaata accgtcagaa
    30661 tgatcatgta aaaaagaata cggataatag ataatcgttt tcgcttcatt tcatcaccta
    30721 gttattttga catctttttt tatcttacta tttctttatc ttcttggcta tttcttcctt
    30781 gatttctgtg tacgccttaa gaaaaaatga attttcctgt attttttgac atcttacgaa
    30841 aatgatcgtt gtttttcagt aaaaacaatt gcccaatgac tgatataatc gttatacttt
    30901 acacagtagg tgattatgtg aaaaaagaaa agaaatatgc aaaaatgcca gatgggagcg
    30961 aaatttacta tgaaaagagc ggtcaaggct tccctctctt tttactgcat ggcaatgacg
    31021 gcagcggccg ctttttttca gaacaggtcc ctgtactcga acgctactat accgtgtatc
    31081 tagtagatag ccgaggacat ggtcgttcga caaacgaagc atctatgttg aattttcagt
    31141 taatggccga ggatctgaat acgatcatgt tgctggaaaa aatcgatcag gcagattttc
    31201 ttggatttag tgatggagca aatctagcac tggtatttgc cagcagcttc cctaaaaaag
    31261 ttcatcgatt gattttaaat tctggaaaca cgcttgttaa aggcgttcgt ttttctgcca
    31321 gagtcatcag taatattcat tatgcatggg tatggttact ctctttattt cgcccaagtc
    31381 ttcgcaaaaa tcttttagtt atcaaacttt tgctgcatga catcgggctt acagaaaatg
    31441 atttaaaaaa aatcaactcc cccactttga tcatcgtggg aaaaaaagat gtaatcaagc
    31501 taaaacattc tttgtatata gctaaaacta taccaaaagc ttcctttgtg cttgtgaaag
    31561 aacaaggaca tgaattagct agaaaagatc ctgaacgctt caatcgagaa gttcttcaat
    31621 ttctttctga aacataacta ttaggaatag aaggtgattt atttgttaaa aaataccata
    31681 caatggctga aaaaccacct aggactgttc aaaacaatct ttttgatttc tgtcattgtc
    31741 attattgtcg gtgaattgat gtccatcggt aaaactctat ctatccagca attaggagaa
    31801 acgtttgcca ctatacctgt atggaaaagc ggactaatgc tattgattgg tcttatctct
    31861 gtgttaccta tggttggtta tgatattatt ttgaatcgga tgcttgaaca aaagcagaat
    31921 cctcgttacc tgtttgagac aagctggctg atcaatacga tcaacaatat tgccggtttc
    31981 ggcgggtttg ttagtgtggg gcttcgctct gaactatatg gacaaaagaa agagagcaga
    32041 aacgtgatcc aagcattatc gaaagttttc ttgtttttga tggctggact ttctatttac
    32101 agtctgcttt cttttttact tgtagtcttc acgccagttg ctcctttttt gaagcaatat
    32161 tggatatggt tgatcggcgg cggtctatat tttcctgtcg tctttttatt tactactttc
    32221 aaaaagaaag gattccttgg tggtacctca cttaaaactc aaggacagct attgctagtt
    32281 tcattgttgg aatggaccgg tgtcctgttt agtttccttt ctgttggtta tttaatggaa
    32341 atccggattg atctgtggca aacaattcca ttattcattg ctgcttcagt gataggaatc
    32401 gtgtctatga ttccaggaga aattgggagt ttcgatgtaa tgatgattat cgggttgtcc
    32461 gctattggtg tgccaagaga aatagtcgtt gtgtggatct tgctctatcg cctgttctac
    32521 tacatcattc cgtttttgat tggaatcgtc tttttcttca aaaatatcgg ttccactttt
    32581 gatcagcgtt attctggtat ccctaaacaa ttagcaacag aaattgcgca taaaatcgtg
    32641 gttgtcttat tatacttttc tggaatcatg ctagtacttt ctgccactat cccgcaagct
    32701 tttacagagt ttcgctggct tcatagtttg aacccattga aatttcattt tattatccaa
    32761 tttcctagta tactattggg atttctttta atcattatgg gcagagggat cgcagcacgt
    32821 gtgaaacgag catatttgcc tacaatcttc ttgattgttc tagctttact ttatgtttta
    32881 ttaagtgatt ttagtttcac accggtggtt ttcttgtcta ttctgcttct gatcattctt
    32941 gcttctaaaa acgaattatt tcgggaacaa ttgatctatt catgggagtg gcgtacgatc
    33001 gatggaatca ttattggtgc actgtccttg ctttacatcg ttattggggt atacaatctg
    33061 ccggatttcc ctcatcggcg tcaccatttt atttcctttt tcttatttcc ttctgaaaag
    33121 atttggtttt cgggattgtt ggccatcatc gctgttagtt tcatgatcgt tctatttgtt
    33181 catttccttc aaggagaaaa gaaacagatt ggcgaagcct ttaatgaaga aaaggccctg
    33241 aagatcctta caacttatgg aggaaactcc gatagtcaat tgatcttctt aaaagataag
    33301 cggatgtttg cctatgaaaa agacggtgaa ccaactgttc ttctccaatt cgcttgcttc
    33361 aataataaat gtattgtaat gggtgatcct tctggtaaga aagaagattt tccagaagca
    33421 atcgaagctt ttatcgaaga aacagatcga ctatgctatt taccagtttt ctacgaaaca
    33481 agcgaagaga ttgttatgat tttgcatgaa ttcggctacg atttcattaa gatgggggaa
    33541 gaagcttatg tagacctgaa tagttttaca acttcaggga aaaaaatgaa gggcactcgt
    33601 gctgtcttga atcggatcga acgagaagga tttacatttg atgtcttaca accaccattt
    33661 tctactgagc aaatgagtac tttcaaaaat atctctgata attggttggg ttcacgaaag
    33721 gaaaaagggt tttctttagg ctttttctct gaagattatc tacaaagagc gcctattgca
    33781 gttgtcaaaa atacccaaga agaaattgtc gcttttgcaa cgatcatgcc tacttacacg
    33841 aacaataaag taggaacgat tgatctgatg cgatatgatt ctaaaaaagc accttctggc
    33901 agtatggatt tcttgttctt gcatttgttt gcctatatga aagaagaaca tatccaatgg
    33961 ttcaatttag ggatggcccc tctttcaaat gtcggaactt ccagaaagag ttttttacag
    34021 gaaaggattg catacttggt ttacgagttt ggttctcatt tttattcttt ccatggatta
    34081 agagaatata aaagcaagta cgctacaaac tgggtctcac gttatactct atattctaga
    34141 gatagttgga ttgcatatgt tatgattgct ttgctgatta ttgataatgc gccagttgag
    34201 cagacacaag gtagaataag tggtttgaaa aaatggatac gaagaaagta ttaaaaactg
    34261 cataccgata gatgaacact ctcatgatga ataaaagaga ctgaagtaaa acgaaagttc
    34321 atgcttctac aatctcttct tatacaattg aagaacaaag agcggtccaa acagaaatcc
    34381 tgtttggacc gctcttttat tttaaacatt tttcattacc aaaatattcg agtcgcgttt
    34441 cttatgcttc gatctctgta acgatacctg aacctactgt ccgtccgcct tcacgaattg
    34501 agaatgtcgt tccgttttca acagcgattg gatggatcaa gtcaacatca atcgtcacgt
    34561 tgtcaccagg catgaccatt tctgtatctt ctggcaatgt gattgttcct gtaacatcag
    34621 ttgtgcggaa gtagaactgt ggacgatagt tgttgaagaa tggagtatga cgtccacctt
    34681 cttcttttgt caacacgtac acttctgctt tgaattttgt atgtggagta atggaacctg
    34741 gtttagcaag tacttgtcca cgttcgatat cgtcacgttg gatcccccgt aacaacacgc
    34801 ctacgttatc cccagcttcc ccgtaatcta acgttttacg gaacatttct acacctgtta
    34861 caactgcttt ttgtgtttca ggtttgatcc ctacgatctc tacctcatca ccgacacgaa
    34921 cagcaccacg atcaatacga cctgaggcaa cagttcctcg acctgtaatt gagaagacgt
    34981 cttccactgg caatagtaat ggtttatctg tatcacgttc tggtgttggg atatattcat
    35041 ctactgtatc catcaattcc ataatagcag cttcagcatc tggatcgcct tgcaatgctt
    35101 ttaatgcgga acctttgatc acaggagtgt catcgcctgg gaaaccatat tcgctcaata
    35161 actcgcgaac ttccatttct accaaatcga tcaattcttc atcatcgact aaatcaactt
    35221 tgttcaagaa aacaatcagg tattttacac caacttggcg tgacaataaa atgtgttcac
    35281 gtgtttgagg catcggaccg tcagttgcag aaacaactaa gattgcacca tccatttgtg
    35341 ctgcccctgt aatcatgttt ttcacatagt ccgcgtgtcc tggtgcatca atatgcgcgt
    35401 agtggcgttt ttctgtttca tattctacgt gtgcggtatt gatcgtaatc ccacgttcac
    35461 gttcttctgg agctgcatca atactagcat agtcttgagg atttgctagg ccttttttgc
    35521 ctaatactgt agtgatcgca gcagttaaag tagttttccc atggtcaacg tgtccaatcg
    35581 taccaatgtt aacgtgtggt ttacttctgt cataatgttc ttttgccata atttacaaac
    35641 ctcctaaata atatagatca ctgaaaaatt tcagctctca cctttttatt atagtctttt
    35701 tttgactaaa tcaaaaagaa tacgtccgac ttactttttg taagattcga actaagctta
    35761 ttatacgtca atattggtca aagtcaacta agagcactcg tctgtcttat acgcgaaaaa
    35821 agtacctttt ataaataaaa aaatgtgttt tttgagaaaa acttcaagat agtccttaac
    35881 tttcttttga agcaataaga acaaaatgag gaaaagttta aaattcagct gttgccaaca
    35941 actttcaata gacgaaatct tctatttcgt taataataag gaaagaggtg aagtacatga
    36001 aaaaattaat tggcgtactt gtcgttttag gcatatttct cggcggaagt tttgcagctt
    36061 atcattattt ttacggcggc gaagcttatt atacaaaaat cacgacgaat ggcgaaatgt
    36121 cagctaccca agcagataac ggagagaaat tcacgactta tacctacaag caagcggctt
    36181 ataataaaga tggtgaaaaa aaacaggtga cgcttcgcga agaaagagaa catccattaa
    36241 agatgaatgc gtatcttaaa ctcaaagtca atcctcgtaa aggtgtatta agctgggaag
    36301 aaataaaggc ttctgaagtg cctaaaaatg cggcagaaaa aatcgataat tagtaaatgg
    36361 tcttaaaatt ttattagata aaaagaggct gggacagaag cgtttaactc caagaaataa
    36421 gaaggagttg cttctgcttc cgccgtttat acgtgtttag agcgtgagac aaaagtgttc
    36481 tttacttttg tctcacgctc tttttttgtt atattcgtct tttccgatcc ttctcttgac
    36541 acaattcatt taactgatca ctggtacttg aacacctaat attctagtca tttttataaa
    36601 cgattcaata cttcatccac atttttgatc atcacggata tcgtaccatc cggattattc
    36661 acaaattcaa tcaaatctgg gttgcgatat acatctactg gtacgatcag ttcgatcccg
    36721 tttgatagct tgaatttttg ttttccaaat tttttctcag aaatttcttg tacttctttt
    36781 acaggaggtg cttctgggac aaatccttgc tcttgtactt cttctttaaa agccattttt
    36841 gccgtgatgt tttccttgaa gactttttcc gcaatcatct catgatccaa ccgacctttt
    36901 tcttctatcg tatcatagac agcttctttc aaatcagcca tgatatcaaa ttcttctgtc
    36961 tcaaattttt ttccaagatg cttggctact ttttggatca cttttacatt ttcttctaaa
    37021 gaaggtgcag gaacactttc gatcactctt ccagaaaaat aaagctcttt tttgccagaa
    37081 aactcatatt ttttttcaat taattcgtag gtccaatcag tcaaattcac agcgaatgct
    37141 tcatctgctt tttgtgtttt cgcccctaga attgctcgat tcaaaatcaa gcggttgtcg
    37201 atccctgctt cgtctgcttc aacaaagtga gtgtaagcct cacgataatt gactttcaat
    37261 aaagataagt acatcactgt atctaattca tacaagacaa caaatacatc tgcactaggt
    37321 gcttcttcac tttcttggta gatatcgaac caccgctgaa cgattgcttc acttgcttcc
    37381 acaaaatttt cttgagcgat tttaagtgat tcaacgatca tgctttcttc tgctagttgt
    37441 ccagtttttg tttgagcaga agagattttt tggatcttct tttgaagaaa atcacgaata
    37501 tattcttttg tcagatccag ctctttttgt gaaaagactg gagaaccagt ttctctgtca
    37561 ataatatgca gaattgcttt ttttaaatag atatccattt tctcattccc ttctgtctta
    37621 gtttacggaa aaaaaatcaa aaataccaga atcaaaatca ttttctttta aacaaaaatt
    37681 tcaagagtag aaacaaaatg gattcttttt ttcgaaaaat gcgctacact tatagttgaa
    37741 cgaataaaaa aggagctgaa agtatgaatt cattaacaag cacttatcgt ctatcaaatg
    37801 gttacgaaat cccggtagta ggattcggca catggcaaac acctgatggg gatgtcgctg
    37861 tttcctctgt taaagaagcg ctggctgcag gttatcgcca tatcgatact gcccaaggat
    37921 acaagaatga agaaagcgtc ggccaagcga ttaaggaaag tggaattcct agagaagaga
    37981 tattcttgac aacaaaatta tggaatgcaa accacagcta tgaacttgtg atgtcttctt
    38041 ttgaagaatc attgaagaag ctccaaacag attatttaga tctgtttttg atccactggc
    38101 caaaccctgt tgcttttcgt gataattggg aacaagcaaa tgcagataca tggcgagcat
    38161 ttgaagaact gtatgaagca ggtaaaatca aagcaatcgg tgtgagcaat ttcttacccc
    38221 accatctaga tacactagca aaaacagcaa aaattatgcc gatggtcaat caagttttcc
    38281 ttgcaccagg cgaattacag acaactgtag ttgagtatgc aaaaaaacat gatatgatcc
    38341 tcgaagcata tagtccatta ggcactggta aaatcttcga tgtgcctgaa atgaaacaaa
    38401 tcgctgaagc acatgacaag acgattgcac aagttgcttt gcgttggtcg ctgcaacacg
    38461 aattccttcc tcttcctaag tcagtgacac caagcagaat caaagaaaat actgaattat
    38521 ttgattttga attaacagaa gaagaaatga aacaaatcga tcagttagat ggtgtagtcg
    38581 gcaaagcaaa agacccagat actacccaat tttaagtcga aaggtgattt tatggatcca
    38641 atcgaacgct tgaattctct ctcggaagaa gttacccaga cttttcattc cgattttgtc
    38701 tttttgatcg atgcagagaa aatccaacat tttcctgcaa gaaactggac acatgatcaa
    38761 atcatcgaag aactgaaaaa acggttcgat cattcgctaa tggtcaaacc ctggcacgaa
    38821 catgaagtca tttattcacc tgaactacct gtttttgcct tgataccgaa aaaatagaaa
    38881 gaatggaacg gattatgtat atatacataa tccgttccat tttttatttt tctttcaaaa
    38941 aacgggaaaa tacgcaaatt tttctgttgt aatttgcgta tacgcaagtt tttttgcatt
    39001 actccttttc atttggctgt ttttttctta taatcgaaag ggtatgagcg aaggagagaa
    39061 catatgaaga aaaaacagaa acaaaaatta ttaaatcaat tccgtccttc attggatggt
    39121 gtaagaggac aattattccg ttctctagaa gaagagagct tgcgacgtta tggtttgccg
    39181 ttacaagtca tgcttgatcc caaaaaccgt caaatcttaa cgatcggatt agctgggaaa
    39241 acaaatgaag atacacggat caacgtgcca atcgatgaca acttcaatac tgtattaaag
    39301 agaattcgtt caggagaaaa cgggattttc gaacgattcc gtgacaatct tcttattgaa
    39361 atcgtgtctt actggaatga tcaacgattg aaaaacgatg aaccaactgc gcaagctgtt
    39421 gcgacaccag ttacagaaga aacagtcagt gtgccagaag aaaaaacgga aaaaccaaaa
    39481 gcggacacaa ctgaaaatac acgctcaact gatacgaatg ccgctttaag ttttgctgat
    39541 ttttcaaaag ccgttgctga gtatcctaaa ttttacacag aacaaaatga acatgaagta
    39601 gttattaatg aaaaaaatgc tgatgaacct cgtaaattag caactatttc tatgactact
    39661 gaaaatgagt tcgttatcga aaaagcactc gaacggaaat acaaagtcaa attgactttg
    39721 attcctttga tcgaacaatt tgcagcgaca gcgattactg atcgataaaa attctatttg
    39781 tcataaaagg ctgggattta aaatcccagc ctttttagtc atataataat ttctacagca
    39841 agtaaaaaga aattccttct aacatcaggc tcaaatatca gcttgacctg tccaacaaat
    39901 cacctatgat cctacaatgt taggcgactt ctcttctacc tgaagatatc ttggagttgc
    39961 ctgatttctt aagatgccta accttaacta taaaaaattc taataataaa catattttct
    40021 gatagagaaa aaag
//
LOCUS       DADGKS010000018        39035 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.018, whole genome shotgun sequence.
ACCESSION   DADGKS010000018 DADGKS010000000
VERSION     DADGKS010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.018"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(111..629)
                     /locus_tag="JXV47_001060"
     CDS             complement(111..629)
                     /locus_tag="JXV47_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAX1487118.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(631..1248)
                     /locus_tag="JXV47_001061"
     CDS             complement(631..1248)
                     /locus_tag="JXV47_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HAX1487119.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(1245..2099)
                     /locus_tag="JXV47_001062"
     CDS             complement(1245..2099)
                     /locus_tag="JXV47_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAX1487120.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(2096..3007)
                     /locus_tag="JXV47_001063"
     CDS             complement(2096..3007)
                     /locus_tag="JXV47_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1487121.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(3048..4382)
                     /locus_tag="JXV47_001064"
     CDS             complement(3048..4382)
                     /locus_tag="JXV47_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAX1487122.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            4590..5420
                     /locus_tag="JXV47_001065"
     CDS             4590..5420
                     /locus_tag="JXV47_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HAX1487123.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(5664..5913)
                     /locus_tag="JXV47_001066"
                     /pseudo
     CDS             complement(5664..5913)
                     /locus_tag="JXV47_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6104..6298)
                     /locus_tag="JXV47_001067"
     CDS             complement(6104..6298)
                     /locus_tag="JXV47_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487124.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(6803..6988)
                     /locus_tag="JXV47_001068"
     CDS             complement(6803..6988)
                     /locus_tag="JXV47_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487125.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(7838..8179)
                     /locus_tag="JXV47_001069"
     CDS             complement(7838..8179)
                     /locus_tag="JXV47_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAX1487126.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(8179..8409)
                     /locus_tag="JXV47_001070"
     CDS             complement(8179..8409)
                     /locus_tag="JXV47_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAX1487127.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            8696..9034
                     /locus_tag="JXV47_001071"
     CDS             8696..9034
                     /locus_tag="JXV47_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487128.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(9239..9478)
                     /locus_tag="JXV47_001072"
     CDS             complement(9239..9478)
                     /locus_tag="JXV47_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
                     /protein_id="HAX1487129.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(9454..9801)
                     /locus_tag="JXV47_001073"
     CDS             complement(9454..9801)
                     /locus_tag="JXV47_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF159 family protein"
                     /protein_id="HAX1487130.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(10533..11114)
                     /locus_tag="JXV47_001074"
     CDS             complement(10533..11114)
                     /locus_tag="JXV47_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAX1487131.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(11297..11923)
                     /locus_tag="JXV47_001075"
     CDS             complement(11297..11923)
                     /locus_tag="JXV47_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAX1487132.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(11945..13276)
                     /locus_tag="JXV47_001076"
     CDS             complement(11945..13276)
                     /locus_tag="JXV47_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HAX1487133.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(13431..13832)
                     /locus_tag="JXV47_001077"
     CDS             complement(13431..13832)
                     /locus_tag="JXV47_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAX1487134.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(13918..14124)
                     /locus_tag="JXV47_001078"
     CDS             complement(13918..14124)
                     /locus_tag="JXV47_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487135.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(14219..15721)
                     /locus_tag="JXV47_001079"
     CDS             complement(14219..15721)
                     /locus_tag="JXV47_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HAX1487136.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(15739..16194)
                     /gene="argR"
                     /locus_tag="JXV47_001080"
     CDS             complement(15739..16194)
                     /gene="argR"
                     /locus_tag="JXV47_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAX1487137.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(16292..16909)
                     /locus_tag="JXV47_001081"
     CDS             complement(16292..16909)
                     /locus_tag="JXV47_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487138.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            17130..18503
                     /locus_tag="JXV47_001082"
     CDS             17130..18503
                     /locus_tag="JXV47_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAX1487139.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            18578..19690
                     /locus_tag="JXV47_001083"
     CDS             18578..19690
                     /locus_tag="JXV47_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HAX1487140.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(19762..21399)
                     /locus_tag="JXV47_001084"
     CDS             complement(19762..21399)
                     /locus_tag="JXV47_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HAX1487141.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(21567..22175)
                     /locus_tag="JXV47_001085"
     CDS             complement(21567..22175)
                     /locus_tag="JXV47_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAX1487142.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(22559..23710)
                     /gene="queG"
                     /locus_tag="JXV47_001086"
     CDS             complement(22559..23710)
                     /gene="queG"
                     /locus_tag="JXV47_001086"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HAX1487143.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(23729..24481)
                     /locus_tag="JXV47_001087"
     CDS             complement(23729..24481)
                     /locus_tag="JXV47_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487144.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(24622..25572)
                     /locus_tag="JXV47_001088"
     CDS             complement(24622..25572)
                     /locus_tag="JXV47_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAX1487145.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(25573..26412)
                     /locus_tag="JXV47_001089"
     CDS             complement(25573..26412)
                     /locus_tag="JXV47_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAX1487146.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(26409..27155)
                     /locus_tag="JXV47_001090"
     CDS             complement(26409..27155)
                     /locus_tag="JXV47_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAX1487147.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            27393..28763
                     /locus_tag="JXV47_001091"
     CDS             27393..28763
                     /locus_tag="JXV47_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAX1487148.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(28818..29714)
                     /locus_tag="JXV47_001092"
     CDS             complement(28818..29714)
                     /locus_tag="JXV47_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAX1487149.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(29995..30672)
                     /locus_tag="JXV47_001093"
     CDS             complement(29995..30672)
                     /locus_tag="JXV47_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAX1487150.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(30763..31668)
                     /locus_tag="JXV47_001094"
     CDS             complement(30763..31668)
                     /locus_tag="JXV47_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAX1487151.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            31843..33267
                     /locus_tag="JXV47_001095"
     CDS             31843..33267
                     /locus_tag="JXV47_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAX1487152.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMED"
     gene            33313..34344
                     /locus_tag="JXV47_001096"
     CDS             33313..34344
                     /locus_tag="JXV47_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAX1487153.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            34351..35538
                     /locus_tag="JXV47_001097"
     CDS             34351..35538
                     /locus_tag="JXV47_001097"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HAX1487154.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            35694..37076
                     /locus_tag="JXV47_001098"
     CDS             35694..37076
                     /locus_tag="JXV47_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAX1487155.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            37203..37433
                     /locus_tag="JXV47_001099"
     CDS             37203..37433
                     /locus_tag="JXV47_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487156.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(37633..38301)
                     /locus_tag="JXV47_001100"
     CDS             complement(37633..38301)
                     /locus_tag="JXV47_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HAX1487157.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(38490..>39035)
                     /locus_tag="JXV47_001101"
     CDS             complement(38490..>39035)
                     /locus_tag="JXV47_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HAX1487158.1"
                     /translation="IHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLDPFMD
                     MFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGWAYQMKAYRNKLK
                     EYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYYYNNER
                     IKQKLNWQSLVQFRKTTVTVV"
BASE COUNT        11346 a         7887 c         6987 g        12815 t
ORIGIN      
        1 caaaacttaa gttattaaga caaatgaata aacaactacg ctttcctcga aacaaaaaaa
       61 taaagcacaa atgcgcattt acgcactcat gctttattcg tacaattaat tcagataacg
      121 gcagcgcata ggatgccaat aacacttcct aaaatagctc ctcctaaaat gtcagtagga
      181 taatgtaaaa gtaaaaaaat cctcgaataa gcgatcaaac aagcaaataa aaaggctaat
      241 attcctgcaa ctggacttaa ttcgaacaac gcagctactg ataaaaaggc tagcgctgta
      301 tgtcctgaag gaaaagaaga agtcttcggt ttacttgtgt aaaggacaag ccgacgattt
      361 ttttcataag gtcttttccg tcttgtcgtt tttttgataa aaagcaaacc aacaaaaaaa
      421 tagatcaaac tgccgataag aatggctaga ccatattctc tagtatcagg tatcaagact
      481 aaaacagcag caaggagcaa ccaaataaaa ccaccattag agatattact gataaatttc
      541 aaaaaattga tttttcgact atccgttttc cgttgcttgg cgaacttgtt gataatacta
      601 tcatcgattt tagcaatcaa acgcaacatg ttattcctcc tttttaagaa ccttttcttg
      661 cgtacgatgg ataaaaagca ggacttgaaa ataaaacaag aaactgaaac ctaataaagc
      721 aaaatagatt ggtcctgcaa accagaatgc gacaagaagg atcaacgtgc ctgccaaata
      781 gaaaagcgcg cttttgaaat cattaaaaaa caagaaaaat gcagtaatcc aagaagcttc
      841 tttttgttcc agttgaagca agattttgta actaaagaga agcgcgctta atagaagcaa
      901 aaacaacgta gtatacatca atgtatagcc aattccccca ccccaatagc ggaaaatctg
      961 ataatcgatc aatagaagaa gaaaataaac acttgctaaa ctatcttgct ttccataaag
     1021 agagaagttc tcacgaaact ttttccagaa tagtgaaccg agctttttct cttcattttt
     1081 tttgtaatga taaatcatat acagaactgt tcgacttgca gttcctaatg tgaaaacagg
     1141 caagacgcac aggaaccata gtagctgtaa atggataaga cgtggaatcc attcaatgat
     1201 ttctaagaaa taatcattgg cttttttacc aatcgatcga ttcatcatcc ttttgaacct
     1261 cctgtcaaat ccatcccttc aatgaaataa cgttgtgcaa aaaagaacag caaaatcgtc
     1321 gggatcaaga caagtgttgc tcctgccatc agataattcc attgtgtcgt tgcttggttc
     1381 tgaaaaactt gcaagccaat ctgtaacgtg tatttttctt gatcttggat atataacaga
     1441 ggacctaaga aatcattcca agctgcgttg aaggaattga tcgcaatggt aatcaaggca
     1501 ggtttcgtca atggaagcat caaatgactc caaatataca aatgattcgc tccgtcgatt
     1561 tcagcagctt cgatcaattc attattgatc gataagtaaa attgacgcat cagaaatata
     1621 ttgaacgcat tgccgaagaa cgatggaacg atcaggggca aataagtacc tacccagccg
     1681 atcttggaga ataatacata ttgagggatc atcgttacaa accccgggat catcatcgta
     1741 gaaagaacca aagcaaacat cagctttttc ccaggaaaat caagcttcgc aaatccataa
     1801 gcaataaaag aatttgaaag gacattaccg atcactacta gcacagtgat gaataatgta
     1861 tttcttgcat agcgccaaaa aggaaaggcg gcaatcgtat ccagatagtt ttcccatacg
     1921 attttttctg ggaaaaaggt cggaggataa cgaacgattt cttccattgg tttcaatgaa
     1981 gtaaacacca tccaaagcaa tggaatgatc aaaatgattc ctattactgt catgaggaca
     2041 taacttagta ttttttttgt ttgccgattc acactggtct ttttgaaata atccatcatt
     2101 tgccgtcacc tccagaataa tagacccact taggtgcaag cttcaaattg acaaacgtca
     2161 gaaccaacac gatcagaaac aggatcattg acatagccat cgcataaccc atatcaaaag
     2221 ctacgaacgc cttgttccac atatgcagat tataaaaaag caaagaattt gcaggtccgc
     2281 ctgttccatt tttcgtcatg acataagctt cttgaaaaat ttggaaagaa ccgatcgtag
     2341 aggtgatcac atcgtaaaaa ataataggag tgattaatgg caaagtaata cttttgaact
     2401 ttccccaaac gcctgctcca tcgatttctg ctgattcata taaagatcta ggaacatttt
     2461 gtaatgtagc taagtaaagt agcattgctc ctccagaact ccatattttc atcaaaatca
     2521 acgcaggttt cgtccattgt ggatcaaaca gccaagctgg tccagggata tggaaccagc
     2581 ccagaaatgt gttgatcaat cctgcagatg gagaaagcag ctgcatccat aagatgtaga
     2641 ctgctactcc tgataagact gccggtaaat agaaagctgt acggaataca ctgattcctt
     2701 tgattttttg attgagtact gtggctaaaa acacactgaa aatcgtcgtc agcggtacat
     2761 tgaagatgac gaaataaacg gtgttgtata acgatttcca aaataaatca tcgtgaacga
     2821 acattctttt gaaatttgct agaccaatga aattcatctt ggatgtcaaa ttataatcgg
     2881 tgaaactacc aataactgaa aaaagcatag gccctagcat aaataccaag aacccgataa
     2941 taaaaggcga gataaataaa taggcccatc ttgcttcttt tttctttcgg atagataaac
     3001 gcttcaaatt ttcttgcctc ctctgtacct agacagtcaa aaatggatta ttgattttgc
     3061 ttgactaagt tttctactgc tttttgtgca tctgccaatc cttcttttgg tgattttgtt
     3121 cctaaaagaa tctggtcaat ctgttcattc actaatgtcg tgtaatccgg agcatctaaa
     3181 ggaactggtg tgatcaccgt atttttaaag ttttcgtccg ccatttgata gatcattttt
     3241 cctttatccg ttaggttgtc attattcact aaattctcat tggctgtctt gctcgccatg
     3301 atatcaaaac ttttttcgcc gaatttttct tgtacttctg gagaagaaag atatttgatg
     3361 aattcataag aggcctcagg atcttttgct ccgtatggta cttccaagac gaatccgcca
     3421 ccccacgacc aatggcctga accttcttct ttttctggga gctgcatcac gccaaaatca
     3481 aaatcatccg gtgcattttc catcaaacta gagtaataat tgatattttg ggcacgcatg
     3541 gctactaatc cggaaataaa tggatcagat acaccagacc caaattcggc ttctaattta
     3601 ttgatcgtat ttttcccata ataatcttgc cagtcttgga tccactccaa ggcttccact
     3661 ttatttttag tatcaatctt gactttttca tctttgtcaa accaactagt cccgttatct
     3721 gcgtttagcg cccatacatc agcccctaaa ttccataatg gataaaaacc gatgcgtgta
     3781 aattcttttc cttctttttt atctagttta cgtgctgttt cttctaattc atcccaagtt
     3841 gtcggtagat cttgttcact gattccagct tctttaaata actttttatt ataaaaaatg
     3901 acttgtgtat ctgtattgaa tgggatcgca taaggatcac cttcatattc tactgtatcc
     3961 caaagctgcg gataaaaatc cttagaagtg tctttttcta catatttgga gagattagtt
     4021 gcttgctgtg cttctgctct ttgggcaacg gaatttatgt cctgtacaat aacatcgggt
     4081 gcatttccag ctgttattgc agataaagat ttagtccaga tgtcacccca tggctgatac
     4141 ttataattta catggatctc gttttgtgat tgattgaaat cctcaatgat ttcttcgata
     4201 gcttcttttc gtgcaccgga tccccaaaag gaccagaaat caatattttt tcttccatca
     4261 cttgtttttt cagaagaatt tgctgcactt gaactggcat cgcttgcatt acttgatccg
     4321 catcctccta ataaaaacaa tgctgaactt gccagcaacc ctgtaaacaa taattttttc
     4381 atattttacc tccaaatttt aatgtaaccg atgccggttt taatataacg atatcatttt
     4441 gttctgaaaa taacaattta taaggtatga ttctaaaaaa attattaatg ataccaatac
     4501 tttatataat tcgcgagcgc tttctttgaa ttttttaatc tttcgtagca gaatgagaat
     4561 gtattaaaaa tagattagga ggaattttga tgtttagaca ccagaaagaa ttgcagtttg
     4621 aagcaaaacc agatcgtccg aatccattaa tcgcgaaata tctgcaggag ctgatcggcg
     4681 gccaatatgg cgagatgagt gtagctatgc agtacctgtt ccaaggctgg agctgccgag
     4741 gagaagaaaa atataaagat atgctgatgg acattgcaac agaagaaatc ggccacgtgg
     4801 aaatgttggc gacaatggtt gctcgtttat tagagggtgc gcctgttgaa gatcaagaag
     4861 cagcgatgca aaaagatcca acaatcggtg ccattatctc tggaatgaat ccacagcacg
     4921 cgatcgtagc tggcttagga cctcgtcctg ctgacagcgt gggcaatcca tggagcggtg
     4981 cctatatcat tgcgagtggc aacttgttag cagactttag agctaattta aatgccgaat
     5041 cacaaggaag acttcaagta gcacgtattt acgaaatgat cgatgatcgt ggcgtaaaag
     5101 atatgctgtc tgttctcctt gcaagagata gctatcatca aaatctatgg gaatgtgcag
     5161 tgaaagaatt agaagaaaaa gaaggttcaa tcttagtccc aagtactttc ccgcgtgaca
     5221 aagaacgaaa agacattgct tatgacttct ataacttctc agagggagac caaagtagtg
     5281 aaggttcttg ggctagtggc aaagcactgg atggcgaagg cgaatatcaa tggttgaaag
     5341 aacctaagat cgaaggcgct gcaccaaaat tagaaccagt aacaccaaaa atgtatggga
     5401 cacctccatt caagaaataa atatctaccc gtagaaacac ccgttttttg ttccacacgc
     5461 tttgtgagca aaactgacta aagtcattaa tcataaccac ccttcaaaag ggtggttttc
     5521 tctagagcta taagctcaaa tcaccggcca gcgcctaaag acgctggctt tcatatttta
     5581 tgttcaagcc atattgcctt tgccagtttt gcccacctct taaaaggttt atgtactact
     5641 ccttagccct taaaaggatc gtcttactct cgtacactca gcttatctaa cgcactatca
     5701 tgtttttctt gttcttgaat gtactttttg atggtcgctt cattttgtcc tacttttgtc
     5761 acatagtatc cttccaccca aaagtgtcga tacccaaatt tatattttag atttgcacaa
     5821 tctcttgatg atctcctgaa tattggctcg atattgatta taaattattt ttcttctata
     5881 ctttggtgtg aatacaatgt ggtatttaca catctacttt gtacgggcta aactatttcc
     5941 ctttattgct ccacccgcat agcaagtggt tttgtatttc aatcgctcgg cgcgctcaat
     6001 taggtctaaa gacaataaat ctaaaaaccc gctgcttcac tgacagaaac aacgggtttt
     6061 cagaaaaaaa tgaaatgaaa aagatctctt acggcaatct attttatttt tttgattttt
     6121 tataaatgga aaatgcttca agaagtccaa gaaataaagc cgtataaaaa caagaaccta
     6181 tgaaatcttt atttattaga tattcaacag aaatcccgat aacactagcc aacaatatat
     6241 ttatcagaag tgtaaaataa ggatgctttt tatagaatag aactagtgtt gttttcatag
     6301 actctccttt cttcatattt ccaattaatc acaaattcac ggcattacta gaaaaattaa
     6361 aggggcgcag aagtggaaaa atactcttcg actttcccta caaaccaggc catcttgtgt
     6421 ttaataacta taccaaatct aaggtacctc taaatctaaa ttccatttgt ggcggtgacc
     6481 tccaattttt aactcttcta tctcccatcc agtatacata accttgatac ttcgaccact
     6541 tatatatcga acacacaaat acctatccat tgcaggagta ctacctaact tagttgctac
     6601 ttgcatctaa ataacagctg aaaagatagg acttactctt agtaaagtat ctgaactatt
     6661 aatttttaaa ctatcatttt tatcctcaac tacatgcaca tctgttgcaa cttcactttc
     6721 tgtctcatcc agataaatga ttaaggaatc gggaattgca atatcttcag ctgacgctgg
     6781 aatagttgag ctaaattagt catcatatct ttattataaa ataaccaaca gcaaaaaata
     6841 caatgaaaaa caaacttgga actaatgtat cattaataaa tgttgaaaaa ttcagcaact
     6901 cattactgta tgattttagc agcccaacca acatataccc tataaaagct aataagatgg
     6961 ttaggaatcc tttagaattt ttactcattc atagacactt ccttaaataa cttttattat
     7021 agaaggtatt gtaaataata atattgacaa aaagtgactc aaaataaaaa aaaccttaca
     7081 ttatactgga atgaactgta ttgatagtgt acctaaaagc tctactgaca taagatcgtg
     7141 taatcggtaa agtaatttta ttaattatac gggatgtaat caattagaga ataaactaat
     7201 cataaaaggt acttttacat tcataattgt cgctttgaga ttctactttg gttcactatc
     7261 tgacccaatt gcacattttc gatcattaca agtattggtg tcgttagaac aactaaataa
     7321 aaactagcgg tagatttttc agaatctatg ctaatttctg tatggatgtt ccagtgatgg
     7381 caaatttctc ttttcattgt ttttcttgtc gcatgatatg cctttttgtg ttattcagtt
     7441 aaactataga aattctttcc tagacagatc ttgatcccaa attttacgtt tttgagcatc
     7501 gatatagttt aaaatgacat tactcatatc taaagagttt agatttttta ggactaaaac
     7561 tgtcagttgt tctttttctt ctttctgtta aagtattgtc gcgacttttc gtatacgtta
     7621 agatatgtcg tgaaaaaaca agttttgtga cacaaaaaaa cgaatgactt gaggaaatca
     7681 cctcaatcat tcgtttaaaa tgctatatat tctttagttt aagatacgga aattaatgcc
     7741 atcgaccaca ctagtagaat gaacgacatt tacttggcct ttttttaatt tcgttatgtt
     7801 tagcatataa aaatattata gagtttactt acaatgctta aaacatatac tgtataatct
     7861 gatcaatttt agccatgtct tgcaatggta agttttctat ttttttgagt tttcgttcct
     7921 taaaatcaag agattttaat tgtgtaataa ttacttgtcc ttttatatct agctcttcag
     7981 gtaatgagta acgtgtcggt aaattcttta tagtggaagt aattggacat atgaccgaaa
     8041 acattgtttt acggttaaat tcataacgag agacgactag tcctggtcgt cttttttgaa
     8101 tttcttttcc tacggaggga tcaaaatcaa tccatacaat atcacctttt ttaggaatat
     8161 aaattctttc ttctgacact ataaaatttc tctcccttca ggagttaaat cttcccattc
     8221 gtctttctca taatactcgg cctcttcccc accactaaat ggatcttcaa tttttggaac
     8281 taacgtaatt gttccatcat cagaatacac aacgatatat tcttggtttt ctgaaggttt
     8341 ctttccgtta tcagaaggta aagttaccac tacagaactt ccttgtaatc tagattttgt
     8401 aacaagcatt atcatcactc ccttaataaa agtatactat ataacactaa gtaacgcaaa
     8461 attccccttt gtaaactatc tagaaaattg ttttgtttaa agtatatctt attggatata
     8521 aatagaaata aattgtagcc agttcatttt ttctttaact aaaaaaataa tccaagaaac
     8581 attgaaccta tggatccaaa agctacccaa atactatagc taaccccccg ctaccttcaa
     8641 ttttgcagat aaaacgcttt gggagaaaat ttcaaagaca acaggccatc ctatcatgcc
     8701 cgattataaa caaaaagctg gctattcctt ttgctctgac aaatttcaat tgggaaagtt
     8761 cacgaaacta gcaggtgaag aagtttcaac tgttcggatc aaagaatgcc cgcttcaaat
     8821 agaaacattg gttcaacgaa tttcaactag acaagacttt gctattgtag aacgtgagat
     8881 cgtagctatt tttgtagaag aagggatttt acatgatcca actcatatca atgtggataa
     8941 atggcaacct cttatctata aattcagaga atatacaact gccaaccagt cgttaacttt
     9001 gaattttaga ttccaagaat tcaaagagtc ataatgataa acatcgttag gtataaataa
     9061 aaaagactcg cagcacgagt aaaaaacaaa tagaagctat acattagaaa ggtcgactgt
     9121 gaccctatag atgcagtata tgcagcttat gagcatttct tctgttctct ttgtttttgg
     9181 gatctgtgct gaagtctttt tcgttttttg ccgctctttc tttgaaaaat cgattatgtt
     9241 ataccttctc cattactaat tcaggcatct gctgagtaat gatttttcgc gcaaaagaaa
     9301 tatctgttac ccaaggttcg atttgttctt cagtcaagac aagcggcatt cggtcatgga
     9361 ttggtgcgac tgtgcggtta ggttcagtag tcattatgat tgattctgcc attttttcat
     9421 cctgatggct acgataaaaa ccgccaatat acactatttt ttccttattt gaaaacataa
     9481 atttgtcttt ttcttcattc cactcattgg gaaaacacaa cgattttgca aaaatggttg
     9541 atgaaaggtc tttttttctt ctactgtctc tgcacgggca ttaatcatca attgtccttt
     9601 tttaaatccg gtaaatcccc acttcatgat ttccggagtg aggatgtttt cttcctcttt
     9661 tcttaacgtc acaacaagat ttgacggaaa aacttctcca gctgctaatt ctgctgcctg
     9721 cttcggttgt ttcgtctggg cttctcgata ataattctga aggagctctg actctagatc
     9781 aaaaaaataa cgaccacaca tcctaatccc tcccaatctt tttttctatc atacactgca
     9841 acaagaagtt cgcaccaaca aaacgctttc aatttttgta gaactaaaaa agttgtgaca
     9901 agtgacaaac tctccagtga atggtattct cctgccaact cctcggtcac aagtcacaat
     9961 attcaacaaa catgagaagc tgctttttga aattgttcct tgtgactcgg agtgaaacgg
    10021 caggcttacg acctctgggt aaacggtgtt caaaagccag tttctcggta ttaagccaaa
    10081 tttatgcaaa aatgtagaaa gctattttca caaaattttt cttaatactc gaaactaagc
    10141 gactttttca caacctcttc cttaaacggt gttcaaaagc ttgcatctgc ggtaataagc
    10201 ccaaccaaac gaaaaatatg agcagctatt tttatttggc tgttcttatt acttgatgca
    10261 gggcagcttt ttcacaacct ctccactaaa cggtgttcaa tcagctaacc ttcggtatta
    10321 gctcaaaaaa cggcaaaata tgaggaacta ttttgccgtt tgtttctcta atactcaggt
    10381 caaagcgctg atttcacaac ctctaataca cggtgttcca gaagtagctt cttcgaaaaa
    10441 taagccgaaa tttcacaaaa atttgagaag caattttcgt aaattccttc ttatttcttg
    10501 aagctgacca cttctgtcac aacctctaat tattaaagaa ccttttgcga agttaacaat
    10561 ctttctttga tcaattgaaa attctgccta agtagtgata gatcctgtgt gactttcaac
    10621 aataagatac ttccctggat ttcagcaatc aacgctttgg cttgacggtc tgcttcttca
    10681 tcggacagtt tttcttcaga aagtgccagg atattttgtt tcgtatactt gacccattga
    10741 ttgactaatt ctagtagcaa cagacggtat tcttcatcca ctgtactcaa ctcaataatc
    10801 aaattaccta caggacagcc atgataagtg atctgtgtct catgatcagc gaaaatccag
    10861 tccaacattt cttctaatgc ttcttctggc tgttttccag catttaagat gtcttcgaac
    10921 aattctgtct gccatacgtc catatgcgca tggatcaccg ctagacaaac ttcttttttt
    10981 gaagaaaagt aataataaaa ttgacctttt cctgtatcag aagctgctag aatatctcgg
    11041 attgacgttt catgatagcc ttttttataa ataagatctt tggtcgcttc caagatcttt
    11101 tcctttgttt tcaatgatat tctccttttt catttctcat agtcctatat tatacagtaa
    11161 attcatcatt ttttcttctt aatcgtttaa aaaagactgt gccaaattat ctgacacagc
    11221 cctcactata aaactgttct catatagcta gatgttcatt gattcaagaa ctgcgaggac
    11281 aaaagcaatt cctatcttat gatagttgct ctaatacttc ctctgttgtc atcacttgat
    11341 ctgcaataaa gccaaagttc gtcaacgctg catccattgc ttcttggcca ggagcaccaa
    11401 ttgcatctgt cgctaccaca acattgaatc cactctctac caattcacgc atatgggaat
    11461 cgctacacaa gtttccgttc attccaccaa gaattactgt gtcgattcca ttttttctca
    11521 attggagcgc caaatcattg ctttctggtc caaagatttt atgaggagag ctgatgatcg
    11581 tattttcatc caaataaggt ttcaattctt cgataaaatc ggctcctgaa ccttcttcca
    11641 ctgattcata ttgacttttt ctagcaaaca tctgctgctc aagcatcata tgttctcctg
    11701 caccgccaaa ttgccattta tggtcatgtg ggtaaaaata atgaggagaa ataaagagtt
    11761 tgtatccttt ttcttttgct tgttttacca tttcaatcat attttcgatc gtattgtatt
    11821 tttctaagat atcttttgtc aaaccaaagc caccgcctgc tggtttcaag aactcgactt
    11881 gcgggtcagt gagaactact gctgtatttt tattattgaa catggtggat tctccattcg
    11941 ttatttattt taatacatca tttagagctt cactcattgt cggatgagaa tagatttgat
    12001 ctctcaataa cgtataagga agttttccat tcatagctag cgaaatcaag ttgatgactt
    12061 catgagaatc ttccgcatag atacttgccc ctagaatcaa gtcagtttca gggtcgacta
    12121 aaactttgaa tacaccttta ggatcttcta atacttgtgc tttagggaca ccgcttgtca
    12181 tatacttgaa taatttgtaa ttgacgcctt gtgctttggc ttgtttttct gttaaaccta
    12241 cattggataa agtcggagtg ataaatacac tgtaaggcac agctttccgg ttattcgttg
    12301 ttcgtttatt ctcgcccttc aactgatcca taatgattcg ataatcatct agagagatat
    12361 aagtgaactg caatccgcct ttgacgtctc caatcgccca aatgttgtct gcatctgtac
    12421 gaaggtattc atccacagcg attgctccgc gatctgttag tttaacatct gtattttcta
    12481 atccaagtga tgctgtactt ggttttcttc cagttgcagc caaaactttt gacgcttgga
    12541 ttgttacttc ttggccatct tctgtaaagg tgacggcagc tgttgattct tggtctgcta
    12601 cttgatctac agatacacct agatggaatt cgattcccgc atttgtcatg tcttctaaaa
    12661 tcatttgcgc gatatcttca tcttcacgtg gaagaaattc agaatgggca tcaagaacga
    12721 caactttaga tccgtattca ttgaacattg atgcaaattc caagccaata tatccagccc
    12781 cgatgatcac taatttttcc ggtaattgtt cctgatccat cgcttgcgta gaatcaatca
    12841 agtagcgact tgtattcaat cctttgattg gtaaaatgat tggttcagaa ccagtattga
    12901 tgaaaatccg ttcgccttca acaatcactt tttcaccatt attcgtcact tcgatttgat
    12961 ggttagaaag aaaacgtgct gtaccgtcca tcactgtccc agttgcctca tcgctgatca
    13021 tatgataatt tttggcgcga agcatgcccg tcaatttttc tttccgagca acagcctctg
    13081 taaagtcgat tcctctttct ccattgaaaa tcaatgattt agaaggaata cagccgatgt
    13141 tgatacatgt tccgccatac atacgtgttg acttttcaac gactaaaacc gattcacctt
    13201 ttgaagctaa cgccttcgct aaagtcttac cgccctttcc aaaaccgatc acaatatttt
    13261 gatatttttc catcattttt ccctcgcttc ttttttacct accgattggt acaaaaatat
    13321 gataaccgat aattgtctat tctccaaatc atctgcttta tttgtcaaaa aaaaccagac
    13381 aaaaagcggt cctttcacgt ttttagtctg gttcgatttc ctttattctt ctaaacaatc
    13441 gttacttcta catcgatatt tcctctagtt gctttggagt aagggcagaa ttcatgcgca
    13501 tcttctgcaa ttttttgggc ttcttcttcg ctgatgccat cgatatgcac ttctaatact
    13561 acaccgatct gatagccgcc atcatctaaa ttataaagag agacacgtgc ttttactgtg
    13621 gactctgctg tcattcctgc ttctttgatc atatgttgta ccgccccatt gaaacaagaa
    13681 gcataacctg ctgcaaataa ttgttctgga tttgttcctt ctgcatggat tcctggagga
    13741 gtgattttca tatgcatcga gccatttggt gcctcgactt ctccattgcg cccgccatgg
    13801 ttgatcattg ctgtttcgta tgcttttttc attgtactgc tcctttcgat tgaccatttg
    13861 ctacttggct ataattatag tgtatgacaa gtaaggcgct ttctacaaaa attctgctta
    13921 ttcgaatacc agaatgccgt cttctactat ttttccaaaa aacaaaaaaa tactactcgt
    13981 gaacaacagc gtcatatttg ttccaaaata aatagcaatc ttttctacat aatcttttat
    14041 atgattgatt ttaagataca tatataccag aaagttgacc ccataaacca atactgttaa
    14101 aaaaataacc atattcgtta ccattttttc ctccttttgc tggtctccct accagcactc
    14161 gatttaacca taccactttt tttgccgtcc aagcaactag cctttcaaaa agactggttt
    14221 attctgctgt taatgattca agatcagaaa aatgtccgaa taattttgct aattttacta
    14281 acgccaactt gttctttccg aattcatcat tttctatctg taatactagt aacggctcat
    14341 gtaagcttaa acggatcaaa aaccagccgt ttccgtatgg ctcttctaga tcatatcgaa
    14401 taccttcttc attttccggg tcgaagttca tccctttttc ttcttccaac agtcgcttca
    14461 tttcttctaa tatcttgttt ccttgttcgc gtggttcatc gctgaacaat tttaatcgga
    14521 tttcttgtac ttctacgggc tgtttcaact ctttgatttg ttcatctaat gtgatacctt
    14581 ttctttttaa ttctggcaaa agcatcagga tctttgcgat gacatatgca ccatcatcca
    14641 gaaaatagtt ttccttgaat gcagcgtgtc cgcttgtttc gatggctagc tgtgtatctt
    14701 tcccaagacg gttaagttct aatgctttat tgattacatt tcgatagccg gaaatataac
    14761 gaacttggat gcctcctttt tcttcaatga atctttgtag atgagaagaa gtaggggaat
    14821 tcgtcacgat tcttgttcct ggatgctctt ttaatacgat tgtacttaat actgcgatca
    14881 aattatttcg attgatcact gttccagaag cactgacaac tgcagaacga tccacatctg
    14941 tatcgaaaat gatcccaaga tctgcttcat ttgctaaaac agcctgcttg atactttcca
    15001 tcgcttcttt attatcagga tttgggatat gattaggaaa tcggccatct ggttccaaaa
    15061 attgggaacc tgttgaatcc gcacctaagc tattcaatac tttttcagca aagaatccac
    15121 cagcaccatt tccggcatca acaatgattt tccaaccatt tagtggtttg ctttctagtg
    15181 ttccaatccc ctttttaatt tttgtgacta aatcttgcgc ataaggtgtc aaaaggtctg
    15241 ctttttctac gcttccagtt tgttcgcttt ttattttttg ctgctgtgat aggataaaag
    15301 caatatcttc tttttctgct cctccttctg aggtaaagaa ttttattcca ttataataat
    15361 agggaagatg gctagcagtc agcataaccg cagcatcgca cgagaactgt tcaaattgag
    15421 tggacataaa catagcaggc gtagtagcta attcgaaatc gatgacatgt atcccttgtt
    15481 ctttcagact ttggatcaac gcctctttca gtgctggtcc gcttatccta ctgtcatgac
    15541 caatcccaat cgtccatttt ttatttggat cggttgattt cttctttttc tttatccagt
    15601 ttgctagtcc ccagccgatc ttttttacca tgtctgtcgt caagtttact tcatatcctt
    15661 caactggtaa tgcgattcct cgaatatccg atccattttg cagcgctttc atatctttca
    15721 tataaaagtc ctcctcattt attccctcat tttttccagc ttttctgcaa atcgctgtgc
    15781 ttcttcttct gagcggcaaa taataatgaa tgtatctaca ccggccatcg ttccgacaac
    15841 ttcagggtaa gccacttcat ctagccaatt cgttaccaca tcggcaccat ttcgttcagt
    15901 caatacgata accatgaact gaacagactg gatacgcaaa acctcgcgtc taattgctgt
    15961 acgcaaacgt tcttcattta aagaaacaga tggctggtta aataatgtat agcgtactat
    16021 tttgttttca ttttgacttt ttactaactt catttctcga atgtctcgag aaatcgttgc
    16081 ttgagtcaca tcggcgcctg cttcatgcag ccgcgcaagc agctcttcct gtgtcccaat
    16141 aggttgttct gtaatgatct ggcggatcag tgcttgtcgc tgtttctttt tcatattaga
    16201 cacctctcaa tgttgattat agcaaaagat aagtaatatt tcttcatatt ttggtatttt
    16261 ttacttttat tttttgtttt cattcaggtt gctaaccttt ttctatttta acacgcaaaa
    16321 tcgtcttcat tttttcaggt gctgattttc ttggatcgct gatgtaaatc tctttgtgtt
    16381 ctttagaagc tctttcatag ccttcttttg cgatgaatgc ttctaatttc tcaaacgttg
    16441 ctggttcttc ggcatagggc ccgacgtgta agatttgggc acaaagacct tcttccatct
    16501 ttttgaatac tacttgttct ttcaagtctt ccggaagttt gctagaacgc tgaatggctt
    16561 cttgtgctat cgcttctgta acaaagtcag gctgtcggat catcaattga taagaaaaat
    16621 gttctttttt catcactggt tcatgcaaat acttttcttg cagtccccat tgtccttcca
    16681 gtggatagac agtatacatc tgataatcag gaatcagcca atttttttta ggcgacatgc
    16741 gtattgcata gctgactgca tatagacagg ctactcttcg tttaaagtct tcctgattcg
    16801 ggtcgccgat ccctctgatg ctaaagaatg attttttagg aacctctagt atttgcgggc
    16861 tttttttcat actatagctc ttgtctttac gccattcaat tttttccatt tttcttcctc
    16921 cgcgaaattc catttagtta tttattatca tacctctttt tgagtgactt ggctaatcgt
    16981 gttgacacta tttttcagtt tgtgctagaa taagtgaagt aaataaatcg tacagataac
    17041 acgtttcggc gtgtcgagag agaggcggtt tctattttta taatagaaat cactctcttt
    17101 ttttacgaaa ttttttagag gtgatgtaaa tgacaaaaca aaaacagctg cttttagtac
    17161 ctgcagtaat tgcaacaggg atgatgtctt ttgcgggcgt attgatcgag acggccatga
    17221 atgtaacttt cccaactctt atcagacagt ttgatttaac gactgcacaa gtccaatggg
    17281 taacaacgat ttatcttttg atgatttcga tcattgttcc gctgtctact tatttgaatc
    17341 gcaattttag tctcaaaaaa ctctttttag cttcaaatct gcttttcttg gcaggtataa
    17401 tgatcgattt cttctctcct accttcatgg tcctattgtt tggtcgattg ctccaaggtg
    17461 cagcgacagg tatcgctctt ccgttgatgt tccatattat cttgacattt gcccccctca
    17521 atcgacgagg cgcgatgatg ggtgtcggta ctttgacaac ggccattgct ccagcaattg
    17581 gccccactta tggaggcatt atgacttcac attttacatg gaatcatatc ttcctgtttc
    17641 ttgtgcccgt tttgtttctt tctttgatta tcggctggtt tgctattccc gagatggcag
    17701 tacaaaaaag tggttatttg gattggataa gcgttttagg aatttgtctt ttgtttagtg
    17761 gaagtctaac atttttgagt acgttgggaa cagtttccag ctggattgct ttaatcatcg
    17821 gcggtattgg ctggttcctt ttttactatc gaagtaaaaa agtggagcat ccactgatcc
    17881 gactgtctat tctttcaaat aaaacattcc gcttgttttt gattggcttc ttagtttatc
    17941 agtttttatt acttggtgta tcttttgtct tgccgaattt ccttcagatc gttcaaggaa
    18001 gtagtccttt tgtcgctgga ttagcgatgc ttcccggcgc agcggttggt gctttgcttt
    18061 ctcctttttc cgggaaaatg ctggatcaat atggtccgaa gaagccaatt tttgctgggc
    18121 tgattctttc tttgattggt tggctagcat tattcctact cataggacac gcttcagtgg
    18181 gtgtattgat tgcttgtcat gtgttttata tgatcggtat cggattatct tacagcaata
    18241 tgatgaccac cggaatgaat gcactgaatg aagaactaca aggagacggg aacgcaatgt
    18301 tcaatacctt gcagcagttt tctggcgctg tggctacttc attagtagcg gtcattatca
    18361 attacgtcca gcatcatact tcccataact atgaagtgtc tactacatta ggatcaaaag
    18421 cagcattagg cgtcttgttg ctgttgcttc tcgtaagctt tgctcgattc gcctattatc
    18481 tgttctttgc taaaaaagcg tagattccat atacggcagg tgttgcatct gccgtttttt
    18541 tgtgtgaaaa tggttgtttg taaaaggagg cttttttatg gaaaaaattg ccattatcgg
    18601 tggcgggatc attggtatga ccctagccag ttacttagat acatcaaaat tcaatgttgc
    18661 tttatttgat gaagggacag gacaggcaac taaagctagc gctgggatta tctccccttg
    18721 gttgtcgaaa cgcagaaaca aacaatggta tcgtctggct aaagacggcg ctgctttttt
    18781 ccctaaactt ataaaagatt tccaacttga tcaaacgatt tacgcacaat cagggacact
    18841 tttgcttcga cctgaaaaag atttagctga attggctgtt cttgccgaga aacgaaaaga
    18901 agaagcgcca gaaattggaa acatcgaatg gctttcacct gaacagacat ctcaagcact
    18961 tccgttattg aaaccagcag tttcactgcg tatcagtggt ggtggtcgtc tggatggaaa
    19021 agcatattta gaacatcttg gtcagcgttt agcacaaaaa caaatggagc agatccaggc
    19081 aaaagtcact ttgcataaga agagcgattc ttggctcatc aagggaccgt ttggagaata
    19141 cacagctgat cgtgtaattt tgacacctgg cccggcactt aagcctttat tacaagaatt
    19201 aggctatgct gcagatatac gtccgcaaaa agggcagctc ttagcatttc agacatctta
    19261 taagatgagt caagactggc ctgttgctat gcttgacgga gaagctgatt tcattccttt
    19321 catggatgga aagatccttt taggtgctac ccatgaaaac gatcaaggct gggatttggc
    19381 tcctactagc gaagcttata agggattgac taagagtaca gaacagttct tgactgatcc
    19441 agatcagata aaaaactggc catacgagtt ccgtgtaggt acccgtgctt atacgtcaga
    19501 tttttcccca tttttcggcg tactgccaga tgatccaagc ttactggctg ctagcggtct
    19561 aggctcttct ggcttgacca caggtcctta tatcggctat ctattagcca acttcttaaa
    19621 tactggtcat tggcctacgg aagattatca aaaggacatc tccacctata ttacgaaaaa
    19681 tccatcatag aaaaacagct ttttcaagta aggatcccga gcgatattgc gcatggatta
    19741 cttcttgaaa aagctgttat tttagttcaa tttctgaatc aaattctcca aactttcttt
    19801 tgcttcatct ggcaagagat cttttcctat ctgagcttca atgaatcgta aacgaatatc
    19861 aagtcgttgt ttcaccagat ttttatagga cgtatcctca aaagaaacag gaaaatctgg
    19921 tataggtaaa tagtggatgt cttcaaatgg accaaacgac ttgaattctg ccgtttgttg
    19981 cacgattctt tcaacgattg acaatgtcgt ttcaggtttg atttttttat catcgaaata
    20041 tccagtattc aggacatagc aggctgtttg ctgtttcaaa aacaactctc gaaaagcttg
    20101 atagtcttcc ctaagaggat agacacggaa aggattagca aatggttcaa tgactagctc
    20161 atctagctgt ctttttgtag tgatattttc cgcgtctgat cgttttgttg ctaatgttgc
    20221 accaaaagac gctgctaaaa ctgggtcatt gatcttgata attggcggaa gcgaatcatc
    20281 tttcatgatc caaaaaacag catcgatctt ttcgctaaga tgatcgactc ggtcgggtgt
    20341 cgcataacgt gatttgactg tccgcccatt tccgtttcgt atatctcctg ttactaggac
    20401 tttttctcct ttacttgtac atgtcacgcc cacattctga caagtaagga aagaagaaat
    20461 ggccggatca tcagacggat agtcttgtgt tttatcaaag taagaaggtt ccaaggcagt
    20521 agcaaaacca ttttttcgag aaataacgaa agcatcgtca tgcaagatcg aaacagagtg
    20581 accttccgta tgttttgcta aggtaatcgt tgattttcca gaaccggaca acccaaatac
    20641 agccatcgta taggtctggt cattactagc atattgtttc atcccaccgt ggcaggcaat
    20701 aaagccattg cgatttccca atgcccaagc aagcgtcaaa gtcgcttttt ttaattctcc
    20761 aaagtaacgt aatcctagca cagccgctgt attatggaga gcatcaaaca aaatgagtcc
    20821 atttggaaat gtttcatgtg tccattcggg atcacaaaag atataaagat ctccctcatc
    20881 aaaggaaaca gacttttgat aagtctctaa gatcttcgaa ttcgctggct gaaaattcag
    20941 caaataagaa tacaaattgt tctcaaatcc ttctggaatc agcaaatgac tttgcacaga
    21001 aaattcttca gataggccaa cgattacttt tgtatggtaa aactggcgct tgcgactttg
    21061 atacacagct tctcttaaaa ttttctcgta tttgctttgt tccttgtcta agtcctcaaa
    21121 gatccgccga gcacttgctg ttcttcccac aatgcttcca tcattgaata ctagtgtcct
    21181 aacatcagct ggtaaatcta gttcttcagc atgtgagatt gttaaatctg tgatgatcgt
    21241 tcctggactc ccttttgcta gttgataagc tgtcttccta tcaaaaactt catgaacatt
    21301 attaccgtaa aatgtcgttt ctacaatcga tcgaatactg gataacagtg gatttccact
    21361 tgtgatttcg tttaattcga gactctcttt tgtactcatg gctcctcctc attccctaaa
    21421 caaaaaaacg ttttctttat tatacattat tcgagttttt atttgtactg ctgcgctgtg
    21481 ggaagcaaac gagttatttt tcacacaaaa aaaccgagaa cttgaataaa caagtttctc
    21541 ggtttcatca ttttcctttt atcggcttag taccagccgt ttgctaacca gaatgtttta
    21601 gcagcatccc atgaaccata acgagatgtt acatattgtt ctgctacacg ttcttgattg
    21661 gcagctgaat agtcgccgtt taagtatgaa gcatctaatt gataacggcc gatgtaacgt
    21721 ccgttagtag ctgtgtatga accgcctgat tctttttgtg cgatccattc ttttgcagag
    21781 cttgaagttg gcgctgttgc agcagctggg gcagcaggag ctacttcaac tgtttcaaca
    21841 ggtgcaacgt atgtatgttc ttgcgttgct gtttcagttg tagatgctgt attttctgtt
    21901 gttttgtttt ctgttgttgc tgaagaatca tttgaagttg ggattgttaa ttgttcacca
    21961 acataaatgc ggttgatgtt tgcgatcgaa tttttttcag caattgcatc gatcattgag
    22021 ttgtctcctg caaatttttg tgagatctta gataatgaat cacctgattt tactgtataa
    22081 acttcatcag cgtgagcatt tgtagttcct acaaacattg cagtagcacc agcagcaaaa
    22141 gttgtaccta aaacaatttt cttaaatgaa ttcatattaa actccttttt ttctccgttt
    22201 tttattcttt cgacgctatt aactttatca tttagaaata tttcataggt aaaagaaaca
    22261 tgacatttaa tgacaaaata acgaattatt taatatttgt aacatttaaa caaatatttt
    22321 tttgatacaa aaccataaaa gccttgttgt ataagcaaag taatcgtttt tctatgtttt
    22381 tttatttttg aatgaaaaac gcagattctg taacattcac tgcaataatc cataaaaaaa
    22441 agcaaaaaaa tttttgattt ttatcaaatt ctcttaaaaa aatgtaaaaa atacaaaaaa
    22501 accagtaatt gttacaacaa ttactggaca aaaactttga ataatgttaa ctattttttt
    22561 attttaactt tctccgcaat aatttctggg catgttccaa ttcgtttata acgacttctt
    22621 ctgtttcttt agctaatatt tcatctaata catcaagcca tttttccggt tcttttgttc
    22681 ctagacgtcc aatagcccaa gctgctgttc ctctgatgac agggcggaca tctgttaaac
    22741 attctgaaat ctcaggcaat gccgttcgat cacctagatt agctaaagca atcaatgcgt
    22801 ttctctgcaa aggtttcttc ccacgccatg aaccagctaa atgcccaaat tgctgtttga
    22861 agtctttatt agacatcgaa agcattggct ttaattttgg atatatttcg tctacttttg
    22921 gttccatctc ttcatgaaaa tgaaaatctt ttccttgatt gtaagggcag actaactggc
    22981 agatatcaca tccataaatg acatttcgca tttttttacg atattcttcc ggcatcatcc
    23041 cttttgtctg agtttgataa gacaaacatc gctgggcatt cattcttccg tcaccaagca
    23101 atgcttttgt cggacaagca gtcacgcagc gcatacagtc accgcaacca aattctcctg
    23161 gtttatcagg ctcaaataca atattagtaa cgatctcacc aagatagaca aatgaaccga
    23221 actcttcagt gatcaacaat ccgtttcgtc caataaatcc taaaccagct cgctgtgcta
    23281 cagcgacatc gatcagttct ccagtatcta cttgcggagc tagacgccat tcctcttctt
    23341 tttgccattt ttctgctctt gtttggatga attcgatcaa tcggttcaaa cggtctctga
    23401 gtatatcatg gtaatcgatc ccccaagaag cacgagcaaa ctgcccgcgt ttttcatccc
    23461 taggcacttc ttcatggatc ctagtaggat acgcaagtgc aatggaaatg atcgatttcg
    23521 gctgatcaaa tgtcatttct ggataaagac gctcatcgat atttggatgt tcaaagccag
    23581 aagtatggcc agctgctttt tgttcttcca acgattcttt taatgaatca aaaggttccg
    23641 ccgtggtgaa cccgattttg tcaattccta atcgtttgct ttcttgtatg atttcttctt
    23701 ttaatgtcat ggtcttcctc gcttgctgtt aacggctgta taacccataa tatagttttt
    23761 cttttttcag ctggacaaac tggatctgct gatcggcaat cttcttttct tccatccatt
    23821 tttttcttgc agcaaatact tcccaataat ttgttgaaat taattttctt ttgttatcta
    23881 atgcattaaa aaaattcaat gaaactggtt ttgtacttaa cagttcatgg agccttacct
    23941 cttcccatgg cgaaaactca gacagatcgc gggaatacaa tacttcttca tagagatttt
    24001 tttgctgtgt gtacgtgaat gtttgcggga ttttcccagg cctagcaatt tctactagac
    24061 gattataaaa catattcatt aatttgctgt tggcaataaa ttgactttta taataggccg
    24121 actggatctt tttgattact ccttctgctt tgatgactga aaataatgca ggccatgctt
    24181 tgacggttat ttcgtcgttt tgtttaacta atacgccagg tgtgaagccg actggagaaa
    24241 ggaacacaaa ataaccgata ccggtatttt catctaaagg ctgaaattca tcaaacaacc
    24301 atttgcctat gtacagctct tcatctggtt ctgttgtctc attttgattt gctatgaata
    24361 atttagctaa ttctgcttca agaaattgaa ggtcttgatc cttgtcggta ttttcctgct
    24421 ggctgatcaa tcgaaagact tcttctttaa tcgtatattt atctttacgt gtaaaattca
    24481 tagccacacc ttccttcctt actctaacta taacggaatt tcttcaaaaa aggtatctgt
    24541 acgacgaaaa acagcataat tttttttcat atctcttata aaaaatgcaa ggtctgctcc
    24601 tcaagctaga ccttgcactt ttcagctttc ttttgtttgt gacaaacctt catggatcgt
    24661 ttcaatattc catttcatca tctgatagta agaatctcct tgttctcctt cttttgctat
    24721 ggaatcagtg aacagtttat catagatttt caaacccgtt tcttttgcta cccgttccat
    24781 gcttcttgag tctacactgg tttccacgaa taaaaccggt acttcttttg ctcttatctg
    24841 atcaatgatc gctttcattt gatcaggcgt accttgactt tctgtattga tctcccatat
    24901 ataagctgct ggcaaatcat atgctcgtga aaaatacttg aatgcccctt cacttgttac
    24961 taataatttt ttgttctctt cgatagaagc aaaactttcc ttcgcttgtg tatctaattc
    25021 ttttagtttt tccacatatg cttctgcatt ttttttatag agtgtcgcat tttctgcatc
    25081 tttttcagag aatatacgtg cgatttcctc cacatatttt attccgttag ataggtctag
    25141 ccaagcatgg ggatctgctt ttgtatgttc ttcaccgcta gttaaataaa gaggttctac
    25201 atttttgcta actgcaaaat aatcttttcc ttcttctttt ttagccgttt ccatcaagtt
    25261 atcgaaccag ctgttacctg tttcaagatt caaaccgttg tataaaataa catctgcatc
    25321 gcttgccttt ttgatgtctt ctggtagtac ttcatattca tgcggatctg ttccgactgg
    25381 tacgatactg tggatatcta tttgatctgt tccgacctct tttgccatgt ccgccaagat
    25441 cgaattggta gccacgactg acaacttttc tttacttcct tcatccgctt ggtcagaagc
    25501 ctgctttccg caaccggcta ataccaagaa actaactgcc aagattaaaa agagtgattt
    25561 ttttgttttc atctatctgc ttcctttctg aaataaaatt ccttttgttg gagaaaataa
    25621 aaaagcaagg ataaaaaatg cggtacatgc taacacgatc gtagctcctg atggccaatt
    25681 gtaactataa ctgaaaaaca caccgacaac tgcacttagc ataccgattc ctgcagctgt
    25741 aatgatcatt ttcagtaaat ggttcgttag caagtaagcc gtggcggctg gtgtgatcaa
    25801 catggcaatc accaagattg ttcctactgt ctgtaaactg actacagcca ctaatgtcaa
    25861 aaagaacatc aaaagataat ggatcagcga tgtgttcagc ccataagctt ttgccattgt
    25921 cggatcgaat gatgtgatct tcaattcttt ataaaagaaa aagacaaata tcaagacgat
    25981 tccactaacg agtgctgtca gcaacaaatc gctttcccta acagctaaga cattcccaaa
    26041 taaaatatga tacaaatctg tcgcactctg ggcatatgaa atcaagataa tccctaatgc
    26101 aaaaaaggag ctaaagacaa ttccaatcgc tgtatcattt ttcaatcggc tccgctgagt
    26161 cacgaaacca atcactgctg ctgttagcat cccaaaagca gtggctccaa agatgtaact
    26221 aaaaccaaac atataagaaa tggctacacc tggaagaact gcgtgagaga tagcgtctcc
    26281 catcaaagac atccctcgta aaataataaa agaaccgatg actccagaag caagtcctac
    26341 aagcatggaa gtgaccaaag cgtattgcag gaattgataa ttcattaatc catcaataaa
    26401 ggattggatc attttttctc tcctcctttt actaaatgtc tgatgatctc accataggcc
    26461 aattgaaggt tcttcgatgt aaagacttct tgtactggac cggaagcgat cagctgttta
    26521 tttaaaagaa taacctcatc gaaatattct tctactttat gaagatcatg atggacgatc
    26581 aaaatcgttt ttcctgaatt cttcaattcc tgcaagatgt caaagatctt tcgttcactt
    26641 aacgcatcaa tccctacgaa tggttcatct aaaaagatcc attctgctcc ttgggctaga
    26701 gctcttgcaa taaaaactct ctgaagctgt ccacccgata gttcgctgat ctgtcttttg
    26761 gcatattctt ccatccctac ttttttcaaa gcttgtcttg cacgttcttt ttcttttttc
    26821 ccaggtcttt gtccaattcg taaagatgga tatgttccta aaagtacaac gcctaataca
    26881 tcaattggaa aggaaagatc caattcactt cgctgttcca cgtaggctat ttttttacgg
    26941 actgagttta ccgactgtcc agaaaaggtg actttaccag tagtagctgg tatcaactct
    27001 agcaaagatt tcataaatgt tgattttcct gcaccgtttg gtccgataat accggtaatt
    27061 ttttgtggat ttatcgtcaa gttgatagtt ttcaaaacag ttttcccttg ataagcggct
    27121 gaaaggtctt gaattacaat ggccgtacgt tccaaatctt acactccttt ttaggtttac
    27181 ctaacttttt atttaaatat agtttaacta aaatggaaag cattttcaag tagaatgatg
    27241 aaaaagtttt tttcgaattt tcctcgcatt ttatgaaaat tttctgtaga atcacatcaa
    27301 gagttcaata aggctaacct aataatgaaa aacatgtgtt gaaacgtttg attatttttt
    27361 cttgttgact caacaacgaa aggagttttt gtatggaaga agaaaagtta actcgaagtc
    27421 ttagtgcccg tcatatccaa atgatcgcac taggtggaac gatcggtgtc ggtctgttta
    27481 tgggtgcctc ctcaaccata cgttggacag ggccctcagt gatgggagcc tatgcgattg
    27541 caggattctt tttgtatttg attatgcgtg ctttaggcga aatgctttac gttgatcctt
    27601 cgactggttc ttttgcaaat tacgcgagcg agtacatcca tcctgtggct ggctacttga
    27661 ccgcttggag taatattttt caatatattg tcgtaggaat aagtgaagtg attgctgtag
    27721 gatcttatat gaattattgg tggcctgatt tgccggcaat tattcccgga atcattgtcg
    27781 tcttgtttct tatgctggca aatcttattt ctgtcaaggc gtttggcgaa ttagaatttt
    27841 ggttttcgat catcaaagtc ataacgatca ttttgatgat cattgcaggt cttggggtaa
    27901 tcttatttgg atttggtaat catggtcagg cagtagggat ttcaaatctt tggaaaaatg
    27961 gtggattctt cactggaggc gtcaaaggat ttttctttgc attatcgatc gttgttgctt
    28021 cctatcaagg aatcgaactg atcggaatga ctgctggtga agcagagaat cctaaaaaga
    28081 cgatcattga agctgtccag tccactatcg gtcgaatctt gattttttat attggtgcta
    28141 tttttatcat tgtgagtatc tatccgtgga atcaattgag tgagattggt tcaccttttg
    28201 tacaaacttt ttctaaagtc ggcattacat ttgctgcagg actgattaat tttgtcgtga
    28261 ttacagcggc attatcaggt tgcaattcag ggattttcag cgcaagtcgt atggtctata
    28321 cacttgccat aaatggaaag atgtctaaaa aatttctgaa actatctcgt cacggtgcgc
    28381 ctttttatcc tgtcgtagca atctcaggtg gaatcttaat tggtctgatc ttaaattatc
    28441 ttctaccaat gttcatcaac cagtcagaaa atattttcgt tttcgtatac agctcaagta
    28501 ttttgcctgg tatggttcct tgggtagtga ttttgatcag cgagattcgc ttcaaaaaga
    28561 agcacgcaga taaaatgcat gatcatcctt ttaaaatgcc actatctcct tatacgaatt
    28621 atgtgacact tgctttttta gctatcgtat tgattttcat gtttatcaat cctgaaacga
    28681 gaatctcatt gattattgga ctcgttttct tgctttacat gacgatccat tactttgtac
    28741 gcgaaaaaag aaccggaaaa taaaaaaaga acgaagcttc accttagtgg aagcttcgtt
    28801 cttttttatt gcttttatca attcaatttt agcgtctcac cgggagtcag gaaataattc
    28861 tccatgctca tcccattcag cgacaagatc gtttctactg gtacgccagt tcgttcggct
    28921 atttgatttg gaccttctcc ttccaaaact acggttgtcg cagcctgtga agtcgcgctg
    28981 ttggtattag tttcagagga atctgttgtg tcttgtgttg ttcgagcttg catttcagaa
    29041 gcttctaccg actctgctgt ctcagaatca gaagatgttg tgtcttgtgt gcttgttgac
    29101 tctgcttgaa gagaggcgct agtctgcaaa taaatatcgg aaatcttagc gacatgattc
    29161 gtataattag ccgataattg attgatcaaa gtatctaagt ctacaccgtc tttattttct
    29221 gctgcctgat acgctgcacg taattttctg atcccttcgt cggagattgc ttgaagctca
    29281 cgtgcttttt ggttagcaac tgctgataaa ccagctattc cctcttgatt tccctgaatt
    29341 tctgtctggt attcttcaat caatgcaggc gtcttttctt cgatcttttt cgaataatca
    29401 tttacgattg cttgaagttg ctctggcaaa ccatttgctg ttttttcttc agaagtttgt
    29461 gtctcttttg ttttagttga tgactcactt gtttgtttcg tctctgtttt ctttgtcgtt
    29521 gtttccgtta tggtcgtact tttcgcttct gacgaatttt ttccatgaaa atatagaccc
    29581 gcaactcctc ctgctatgat caaaaacacg gcaactgctg ccccaatcat gatcatccgc
    29641 ttacgagctg cctgtttttg ctgtcttctt cgggtcatcc gaacattttc tccccactca
    29701 ttttcatcat acattttttt caccaccaat ttttatgtat aatagcgtta tcaaacgctt
    29761 catattctta ttgtagcaaa taattgtcgc tgtgcacatt tttatctttg ttatttataa
    29821 gaaaatttca ccagttgaga tgattccaag attgtccgtc gatttctcct tgcagctgca
    29881 ttgttcgttc gtctatctca gccatcagtt tctttatttc atataagagc gcacggtctt
    29941 gatattctga tttttcgctt aattcatcta attgttggat cagccaatca tttgtcataa
    30001 tgaagttcct ttcatttctt gcagtgtaaa ggtcaagtct tcgatctgct cttttgcctc
    30061 agtcagtgct tctacgatat atgcttgttt ttcagattct tcttcctgca ttttctgatt
    30121 ttcctgtact ctttgaataa accagtcaat ccgctgagtc agcgatggtt tgccttccaa
    30181 tgagagatac tgctgataag caattagctt ctcccaacgt ttttcctggg ataaatacat
    30241 aaattgtgct aaaacgaatg gcggaagata ggtcatatgg aatttatttg cgattcgctg
    30301 atacggcctc aaaaattcgg aaatcgtata ttcttctttt cctccagctt ggtattcttt
    30361 ttccgccaca cctgttgtca atacgattcc tagttctttc ccttttaata catgtgctgc
    30421 tcgttccaag acattatctt gccaaatttt taaatgagca ggagaactat accagtaaaa
    30481 cggaaactgg aaaatgatcc gatcatgctg ggccaagagc tgtagttcag tctctatatc
    30541 tatttttccg tctggataac ttgattccaa atgatgccaa gtagctggta aaccagcaga
    30601 agcttctttg aaaaattgct gatttaaaga ttcttcgatc gttggatggc taatgatgat
    30661 aagtgtacgc atcccttttc ctccttttta gtcttcgctt tacagtgtag cataaccgcc
    30721 acaagtttct tttgccgatg cttgtcattt taaccagact aatcaggttg tccaagaaac
    30781 tgcggtttgt ttttccaact gttttttcaa ggtatccaaa gcaatattct taaaattttc
    30841 gtttttcata cgtttacgat agttcgtagc cgtttctccg gtactctttt tgaacattcg
    30901 gctaaatacg actagactat tgaaccctac ttgataggca atactttcca cggattcatc
    30961 cgtcagagaa agaagaaacg cccctcgatt gatccgtacc ccgatcaaat attccttgat
    31021 actggtaccc atatgatttt tgaatactcg cgacaaatgg ctccgattga ccgctaaatg
    31081 ctgggcgatt tcctcaacag acaatttttc agcataatgt gcctcgatgt atttgactgt
    31141 ttcaacagct aaagaggaat gaaccttttg tacaccaccg ctgacctttc cgccatcttt
    31201 taaaaggact gataaaaaac ggtaggttaa tgctgttaac tgtaattcat tttccaaggt
    31261 ttcttccgta tctttcatgc attctaaaat aatgtcgata tatttttgta tgtcagaaga
    31321 gaccatcgtg tattggtctt ctctgaaaag cgactgccga atgatttctt ctgcagcact
    31381 cccaccaaat gaaagccagc aatacatcca cggatcttct ccatctgata agtaaaacgt
    31441 cgagtctcct ggacgaatca agaacagatc accttttttc aattggaatt gttgattttt
    31501 cacatgataa gatcctttgc cttccatcac gacatgcagg atgtaatcat tgcgaatagc
    31561 aggaccaaaa gaatgaaacg gcatcgtttt agagaaacca caaaaatcaa aatacaattc
    31621 tttttctact tgttgatgtt ccttttttaa aaaaatcgat tgctccacgt ctatccctcc
    31681 ttactccttt agtataatgc aacaaaaagt taaataaaag tcacagaaat atattaaaaa
    31741 ggaagcgatt tcttgttaag tttaagtcat taaaagatct ttgttattcg ttgtaaccgg
    31801 tttacttagt attatatatt gaacaggaga ggaatacaga ttatgaaaag caaaatgatc
    31861 caacgtgtgt cctacgcttt aggcgctttt ggacacgaca cattctatgt tacattaagc
    31921 acttatttta tggtattcgt gacaagccag atgttcgcag gaacagataa ggcaacgaat
    31981 gcaaaaatga ttgctacagt tacaagctta gttgtaggta tccgcttagt tgaaattatt
    32041 tttgatcctt tgattggtgg catcatcgat aatactcgta caaaatacgg taaattcaaa
    32101 ccatggttag ttatcggcgg cgttgttagt tccgtactct tggtagcaat ctttaccaat
    32161 ttctttggct tagctactca taatacgact ttatttatca tattatttgc aatcgttttc
    32221 atcttattgg atagttttta ttcatttaag gatatcgctt tttggtcaat gattccagct
    32281 ttgagtacgg aaacaaagga acgtgaaaaa tttgctacgt ttgctcgttt cggctcttct
    32341 ctaggtgcaa atggtactac tctagtcgtt gtccctatcg ttactttctt tacctatctt
    32401 gttactcata aacatattga aggcgcttca ggctggttct ggttcggtgt gattgctgct
    32461 gttatttcag gcggtactgc gattatcact gccttgggca caaaagaagt cgatactgcg
    32521 atccgtcagc aaaatgaaaa agctgggatc aaagatgtgt tcaaagcagt tgctcaaaat
    32581 gatcagttga tgtggcttgc ccttgcttat atcgcttatg cgattgccaa tgcagcaaca
    32641 actgccgtat tattctactt cttcaaatat gtacttggcc aaccaactga attttggatc
    32701 gttggtctag ttgctgcctt acttggttta gtagctgttc cactattccc aatgcttaca
    32761 cgcgtcatct ctcgtcgcta cgtttacctt ggagggatcg caatgatgat ttcttcttac
    32821 tttttcttta cgatcgcagg ttcaagtttg ccaatcgtta tcatcgggct agtattgttc
    32881 tacttccctc aacaattgat tttcttatcc gctttgatga cgatcacaga ctctgttgaa
    32941 tatggtcaat ggaaaaatgg tatccgtaac gaagctgtta ctctatcaat tcgcccttta
    33001 ctagataaaa tcgctggtgc tttgtctaac gggatcgtag ggtttgtcgc tatcgcttct
    33061 gggatgactg gtaatgctac tgctgctgat atcactgctc atggcgtaac gactttcaaa
    33121 gcttatgcat tctatgctcc tgctgctttg atgattttct ccgctattat ttttgcttgg
    33181 aagattacat tgacagagaa aaaacatgca caaatcgttg agaaattgga aaacaaattg
    33241 gctccagctg atacaatgga agattaactt cacgatgcag tagttccttc ccattaagaa
    33301 aggatcttga aaatgaagat tacagaaaaa gattttggcc aaggttatca cttgataacc
    33361 ttggagaaca aaaacaagct agcactttct atctctgatt taggtgctag aatcgtcagt
    33421 ttaaaatcaa atgatcgaga attagttttg ggatttgaca ccgctgaaga atatatcgaa
    33481 aaagatccgt atatcggtgc ttctatcggt cgcaccgcag ggagaatcga aaatggccgc
    33541 ttttctctca atggaaaaac ttaccaatta gccacagatc caaaaactgg acataatctg
    33601 catggtggtg ctcctggatt tgaattaaaa aaatggtctt atgtcatttt gaatggcgaa
    33661 aatgaagctt ctgtcatttt tactactaca agtcccgacg gagaacatgg ttttccaggt
    33721 acaatggatg tggaaatccg ctatactttg acaaaagata atatctggcg agtgacctct
    33781 cgcggcacca gtgaccaaga tactttattc aatccgacaa atcatgttta cttcaacttg
    33841 acgggagatg cttctcagtc aatcgatcaa catgagcttt ggctcaatag cgaagcttat
    33901 gctcctttgc gaacagatag tattcctata ggggtaaaag aaaatgctgc aggaagtgct
    33961 ttcgattttc aaatacctaa aaaattagcg tccgtttttg ctagtgattt ggatcaaaaa
    34021 aatcttgttg acggaatcga tcatccattt ttcttaaaag aaaccggctt gggtaaagaa
    34081 gccgctcgct tgactagccc cgataaaaga atccaagtag atattgctac agatgcttct
    34141 agtgtggtta ttttcactgc aaatttcggc acagaaacac cagaaatgcg caaccgaaaa
    34201 ctggcacatc acggtggcat cacatttgag actcaaacag ctccaggtgc agagcgcttc
    34261 tcagcatttg gttcgattca tttaaaagcc ggatcagtat ttgaaacagt aacagaattc
    34321 aaaatcaaaa caagaaagga ataactcatc atggaaatca aaagaagctt aaacacaaaa
    34381 tttgccgaaa cattcggacc taaaaaaact acacaatact tctcaccagg acgcatcaat
    34441 ttgattggtg aacacacaga ttacaatgga ggccatgtct tccccgcttc catcacttat
    34501 ggaacgcaag gtgtagcagc acctcgagac gataataaaa tattagttta ttccacaaac
    34561 tttgacgata tcggtgtcat tagttttact ttagatgagc tagaatatga taaaaaagca
    34621 aactgggcaa attacgtaaa aggaatggtc cttaaattaa aagaagctgg acactcaatc
    34681 gatcatgggt ttgagttatt agtggaagga acaatcccta atggtgcagg actttccagt
    34741 agcgcttcat tagaattatt agtaggtgtt gtattagaag atctgtttga tttaaaaaca
    34801 gatcgcttgg aactagtcca aacaggtaaa aaagtagaaa atgaattcat cggtgtcaat
    34861 tcaggtatca tggatcagtt tgccatcggc ttcggtgagc tagatcatgc aatcttatta
    34921 gatacaaata cgctgaaata cgaaatggtt ccagtgaaac tagatggtta tgcaatcgtc
    34981 atcatgaata cgaataagcg gcgggaattg gcagattcaa aatacaatga acgccgtagc
    35041 gaatgcgaag aagccttggc acgtttgcaa aaaactttgc ctatctcttc tttaggagac
    35101 ttagatgaag aagaatttga atcaactatt gaccaaatcg gcgatgatac attgatacgc
    35161 agagctcgcc atgccgtttc tgaaaatcag cggactttga aggcaaaagc tgaattagaa
    35221 gctgggaact tagaagcatt tggtcaactg ttaaatgatt ctcaccactc tcttcgctat
    35281 gattatgaag taactgggat cgaattagat acactagtag atgctgctca aaaacaagaa
    35341 ggtgtcttag gtgcacgaat gacaggagct ggatttggtg gctgtgcgat tgctcttgtc
    35401 aaagaagaaa atatacctgc cttcaaaaac aatgtctatg atgaatacat gaaagttgtc
    35461 ggctatgctc cggaatttta tgttgcacac attggaaatg ggacaacaaa gatcgatcca
    35521 gaagctgttc atgtttgata aaaaaatcaa cgatctcagc taaaaacaaa tagataaaaa
    35581 taacctctca gcaatttcca aatgtgagcc ttttgctcgt atttgaaaat tgctgttttt
    35641 tattgacacg gaaagagaac gtgtgttcta attgtgttga agaggtgatt gttatgtggg
    35701 cgaatcaaaa tccggtattt gtttatgaaa aagaaccttc aagagatatt ttatgtattg
    35761 actgcaaatc tttttacgcc tccgtagagt gcgttgaaaa ggatcttgat ccccttacaa
    35821 ctaaattagt agtcatgtcc tatccgtccg attcgacaga aacacggggt agcggattaa
    35881 tcttggcttc cagtcctgca gcaaaaaaag cttacggcat caccaatatc agccgtgcca
    35941 gagatcttcc cttcccctat ccaagtgatt tatatattgt tgccccaagg atggcctatt
    36001 atatggaaaa gaacagagaa atcaattcta tctataaaaa atatgcagac gaagcgaacc
    36061 atcatgtcta ttccgtcgat gaaagcttcc ttgatgtaac aaatagcatg gcactctttg
    36121 gtaaaacaaa tgcgtacgac atggctaaac tgatccataa agatgtgttt gagcagaccg
    36181 gaatctacac gactatagga attggcgata acccgctact tgctaaacta gccttagaca
    36241 atggctcaaa agacggaaag caaatgtttg ctgaatggcg ttatgaagat gtaccagaaa
    36301 agttatggaa aatctcagat atcactgact tttggggaat cggcaaacga acagcaaaac
    36361 gtctgaaaca aatgggtata cattctgttt atgatttagc tcacgcggat tattatcact
    36421 tgaaaagcaa gctaggggtc atcggtactc agctttatgc ccatgcttgg ggcatcgatc
    36481 gaagtttttt gggacaagaa tatacaccaa aatcaaaaag tatcggaaat agtcaaatcc
    36541 tagatagaga ttatacaaga cgagaagaaa tcgagatcgt tatcaaagaa atggccgacc
    36601 aagtcggcac tcgcttgaga cgatctgcag caaaaacaca agtagtcagc ttatgggtag
    36661 gatactcttt aggctatctt gatccaaatg gcaagaccgg gtttcaccag caaatgaaaa
    36721 tcgaagcgac aaatgctagc agagatcttg cagatgcttt attgaccatt ttccaccagc
    36781 attaccacta ccaggatatt cggcgtgtag gcgtgaactg ttccgacctc gtatacgcga
    36841 caggtttaca gcttaacctt tttgaagatc ctgaaaagca gataaatgaa gcgaaagttg
    36901 attttgttgt cgatacgatt agaaaaaaat acggctttca atcaatcatc catgcgcata
    36961 gtctcttgca aggaggacgc gccatcgcac gtagttctct cgttggcggg catgcaggtg
    37021 gtatgagtgg attagaaggt ggaaaagatg agacggacag caaaaaaatt cattgactat
    37081 aacgagtatc gagatcggcc atttggatta aaatggggga ctgcttttgc gatggaagaa
    37141 ctagtcaacg gtatcaaaaa aatgaagaag aagcacgcaa acagcctctt cctaaacaac
    37201 aaatgacatt gcaagaaatc gatagtatac tgacagaagc ctttttatct cgtaaagcag
    37261 taatcattca gctcaattta aaagatgaat ttggaagact cttggatgag gtcgaagggc
    37321 acttcattgg tgaagcctat gaagattact ttatgattga ccatcagccg atattgtggg
    37381 aagacgtacg gtatattgag ttaaaggaaa caaaaaaatg gtttgtgaca tgagaggttg
    37441 tgacagaagt gatcaacttc aaaaaataag aaaggatttt tcgaaaattg cttcttaaat
    37501 ttttgtggaa ttttggctta tttttcgaag aagcaacttc tggaacaacg tatattagat
    37561 atcagaggtt gtgaaaaagt cgcttagttt tgagtaacaa gccaaggcgc tgatttcaca
    37621 acctctgtct atctatccat ctattcggta agattcatgc atgacgtctt ctttatttag
    37681 tatgtagagc cctttttctt ctgaccattc aacataaatc agctgtttta catctgcata
    37741 gccttctttc ttcaagttct ccataagcca tgcttcagtc aattgattgg actgaagcac
    37801 tttatgctga atttgccctt catctacaag caggatcgat aaagctttgt cttcatctga
    37861 ttttttcaat acactcattt gaccggcatt ctctaggata acatgtttgg cattttcaag
    37921 aaaaaagcat tcttgctgtc ttaagattgc tcgcaactgc tccatctcga tatggttatt
    37981 tgtcaactct gtcatgttga tgacgccgtc tttgattaga acagatggct cgcctttgac
    38041 ccaacgattg accttttcat ttttttggac gatacgttcg ataccataaa tcattactgc
    38101 ccaaagcgca atggcaaata ggacatgccc tacatggaca ttgtcatcat aggttgattc
    38161 ttctaagatc ccacctaaaa caagcgtata gactaaatca aacggtgtga tttctgacat
    38221 ggatttcttc ccaagcaaac gtaccactaa taataaaccg atcaacccga acaccagttt
    38281 cattgtaatt gaaaaaatca ttttttctcc ccctaactat ctgttaatta aattatatat
    38341 gctttctcac gaacacgcat ggaatataca aggaagaaat gtatcctttt actaaaaaaa
    38401 ggactgtgac actgtagtga cccccaaaag ttagactttt ttggagtgga gaaatccact
    38461 cctttttttt atgctctaaa atgatatttt tacacaaccg ttacggttgt tttacgaaat
    38521 tggacgagac tttgccagtt taatttctgt tttatccgtt cattattgta gtaatagata
    38581 tagctatcga tggctgattt taattcctcg aaacagttat aaactttccc gtgaaaaatc
    38641 tcttgtttta ataagccaaa aaaattctcc ataagtgaat tatctaagca gttccctttc
    38701 cgagacatgc tttgaaagat tttgtactcc ttcaatttgt ttctataagc tttcatttga
    38761 tacgcccaac cttgatctga gtgaaacgta cgacgatagg gacaatcgtt agtggtctgg
    38821 atagcttcct ccaaaccttc cattaccgct aatgcattgg gcttttcaga gatacgatag
    38881 gataaaatct cactattgaa catatccata aaaggatcta gatacaattt cttttgacgg
    38941 ataatgcctt tggcatccac ttcatggtat ttaaattcag ttgtatccgt cgtgattttc
    39001 tgatggcaga tactggtgta gaaacgacga tggat
//
LOCUS       DADGKS010000019        37244 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.019, whole genome shotgun sequence.
ACCESSION   DADGKS010000019 DADGKS010000000
VERSION     DADGKS010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37244
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.019"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..839
                     /locus_tag="JXV47_001102"
     CDS             <1..839
                     /locus_tag="JXV47_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAX1487159.1"
                     /translation="YQLVETQAPTGYELDATPIEFEIERSQTAVVELTKANRLTPGGV
                     VLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGVYQLVETQAP
                     TGYELDATPIEFEIERSQTAVVELTKENRLTPGGVVLTKIDDQSGEVLQGAVFELQDA
                     NGTVLQSGLTTGADGKLAIDGLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIF
                     LTKENRKVADSSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKR
                     NI"
     gene            complement(1263..1433)
                     /locus_tag="JXV47_001103"
     CDS             complement(1263..1433)
                     /locus_tag="JXV47_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAX1487160.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(1627..1806)
                     /locus_tag="JXV47_001104"
     CDS             complement(1627..1806)
                     /locus_tag="JXV47_001104"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487161.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            complement(1816..2040)
                     /locus_tag="JXV47_001105"
     CDS             complement(1816..2040)
                     /locus_tag="JXV47_001105"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487162.1"
                     /translation="MNGSIKKILRSIDKNLMITEVSYETLQKKKTLIVAAVLFPAPCV
                     CRNCGSAVVDGNRKLMVVKNKKKETIVHFE"
     gene            2193..3305
                     /locus_tag="JXV47_001106"
     CDS             2193..3305
                     /locus_tag="JXV47_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAX1487163.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(3383..3676)
                     /locus_tag="JXV47_001107"
     CDS             complement(3383..3676)
                     /locus_tag="JXV47_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HAX1487164.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3844..4158
                     /locus_tag="JXV47_001108"
     CDS             3844..4158
                     /locus_tag="JXV47_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HAX1487165.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            4179..6158
                     /locus_tag="JXV47_001109"
     CDS             4179..6158
                     /locus_tag="JXV47_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAX1487166.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            6171..6497
                     /locus_tag="JXV47_001110"
     CDS             6171..6497
                     /locus_tag="JXV47_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HAX1487167.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            6513..7031
                     /locus_tag="JXV47_001111"
     CDS             6513..7031
                     /locus_tag="JXV47_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487168.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            7031..8383
                     /gene="celB"
                     /locus_tag="JXV47_001112"
     CDS             7031..8383
                     /gene="celB"
                     /locus_tag="JXV47_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAX1487169.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(8467..9972)
                     /locus_tag="JXV47_001113"
     CDS             complement(8467..9972)
                     /locus_tag="JXV47_001113"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HAX1487170.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(10064..10654)
                     /locus_tag="JXV47_001114"
     CDS             complement(10064..10654)
                     /locus_tag="JXV47_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAX1487171.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10833..12479
                     /locus_tag="JXV47_001115"
     CDS             10833..12479
                     /locus_tag="JXV47_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAX1487172.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            12528..13247
                     /locus_tag="JXV47_001116"
     CDS             12528..13247
                     /locus_tag="JXV47_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAX1487173.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13726..14673
                     /locus_tag="JXV47_001117"
     CDS             13726..14673
                     /locus_tag="JXV47_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1487174.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14685..15605
                     /locus_tag="JXV47_001118"
     CDS             14685..15605
                     /locus_tag="JXV47_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAX1487175.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15646..17103
                     /locus_tag="JXV47_001119"
     CDS             15646..17103
                     /locus_tag="JXV47_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAX1487176.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            17448..18062
                     /locus_tag="JXV47_001120"
     CDS             17448..18062
                     /locus_tag="JXV47_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAX1487177.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            18055..19779
                     /locus_tag="JXV47_001121"
     CDS             18055..19779
                     /locus_tag="JXV47_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAX1487178.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19776..21227
                     /locus_tag="JXV47_001122"
     CDS             19776..21227
                     /locus_tag="JXV47_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1487179.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(21699..23852)
                     /locus_tag="JXV47_001123"
     CDS             complement(21699..23852)
                     /locus_tag="JXV47_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAX1487180.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(23854..24900)
                     /locus_tag="JXV47_001124"
     CDS             complement(23854..24900)
                     /locus_tag="JXV47_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAX1487181.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            25050..26339
                     /locus_tag="JXV47_001125"
     CDS             25050..26339
                     /locus_tag="JXV47_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HAX1487182.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            26352..29054
                     /locus_tag="JXV47_001126"
     CDS             26352..29054
                     /locus_tag="JXV47_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAX1487183.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            29039..29896
                     /locus_tag="JXV47_001127"
     CDS             29039..29896
                     /locus_tag="JXV47_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAX1487184.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(29967..30824)
                     /locus_tag="JXV47_001128"
     CDS             complement(29967..30824)
                     /locus_tag="JXV47_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAX1487185.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            31035..33206
                     /locus_tag="JXV47_001129"
     CDS             31035..33206
                     /locus_tag="JXV47_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAX1487186.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPAVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            33274..33615
                     /locus_tag="JXV47_001130"
     CDS             33274..33615
                     /locus_tag="JXV47_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAX1487187.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(33891..35645)
                     /locus_tag="JXV47_001131"
     CDS             complement(33891..35645)
                     /locus_tag="JXV47_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1487188.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLSFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQCISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(35656..36492)
                     /locus_tag="JXV47_001132"
     CDS             complement(35656..36492)
                     /locus_tag="JXV47_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAX1487189.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            complement(36494..37177)
                     /locus_tag="JXV47_001133"
     CDS             complement(36494..37177)
                     /locus_tag="JXV47_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HAX1487190.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLMPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
BASE COUNT        12013 a         6553 c         7638 g        11040 t
ORIGIN      
        1 catatcagct ggtagaaact caagcgccaa cggggtatga attagatgcg acaccgatcg
       61 agtttgagat cgaaagaagt cagacagcgg tggtagaatt gacgaaagca aaccgactta
      121 caccaggcgg tgtcgtgttg acaaagatcg atgaccaaag cggggaagtc ctgcaaggag
      181 ctgtttttga gttacaagat gccaatggaa ccgttctgca gtcaggtcta accacaggag
      241 cagatggaaa actggcgatt gacggcttag caccaggagt gtatcagctg gtagaaaccc
      301 aagcgccaac ggggtatgaa ttggatgcga caccaatcga gtttgagatc gaaagaagtc
      361 agacagcggt ggtagaattg acgaaagaaa atcgacttac accaggcggt gtcgtgttga
      421 caaagatcga tgaccaaagc ggagaagtcc tgcaaggagc tgtttttgag ttacaagatg
      481 ccaatggaac cgttctgcag tcaggtctaa ccacaggagc agatggaaaa ctggcgatag
      541 atggcttagc accaggagca tatcagctgg tagaaactca agcgccaacg gggtatgaat
      601 tggatgcgac accagtaact ttcaagatcg aaaaagaaca agaagtggcg atctttttaa
      661 caaaagagaa tagaaaagtt gctgatagct cagatataag aggaaacaat ccaacaagca
      721 gtggaaataa gcatcttcca aaaactggag aaaccatcat tagccagttt atattgtcaa
      781 tattgggtgt gctacttgtt ttcatcagta taaaatttag aaagaaacga aatatatgag
      841 ctaaaataaa aaattgaata agcatagttt ttaaaatcaa ctagtaccca tcaattgaat
      901 ggaaactacc gattttagaa ggggtataca aacaaatatt agtatcggag tagagaaggt
      961 tgaacccaac cagtaaataa gtaaagacaa ttttgtgctg cgttgagaag tgaaaaataa
     1021 acctttgtag taatactagt taataaaaaa tatacaaaaa cactgcgaaa atcattcttg
     1081 agtttcgcag tgttttttgc ctaatgactc aagtttattg ggtaatactt tgattttctt
     1141 tctacaaata atcagcgatc agttgtaatt ttttctctag ttttaatggc tctttgtcaa
     1201 taaggagaaa aacaagtcgg gtcttttgtc tcggaaagct tcaaccaact cgtgaataaa
     1261 ggttacgcct ccttgaaagg cgtggaaaaa ccaagtaatc gatcaatcac caatttcgca
     1321 tttggtagaa catgtttggt gagctgaaag taggtggcgt tcatgtctgt aactaagaat
     1381 tctatttctt taggattagt gcagctaagg aaatagtttg ttaatcgagg aattttttgt
     1441 gtaggtaaat tttctcgatt aatttttctg tctcgccatc cgcggaaata aaactcagtt
     1501 tatcctcaac ggaaacgtga gaacgaaatt cacaaccctc aacactcaag acagaattct
     1561 tttggaagac tttggtaaat agcttctcaa ctctttcaat gtgcgaataa cggttgtcaa
     1621 agatacctaa caacttttcg aaataaaaaa taacgacact ttttcagtca gtaaagaagt
     1681 gattttatgt ctgacatgat ttgaaatcga gtgccttgga cggataaaat aactttgagc
     1741 gttccaatgg cttcgacagt ttttacaggt atagcgctgc ttttttaggc gtataaccat
     1801 tggcatatga ttatattatt caaagtggac aatggtttcc ttcttcttgt ttttcaccac
     1861 cattaatttc ctatttccat ctaccacagc agaaccacaa tttctacaga cacatggagc
     1921 agggaagaga actgcagcaa cgatcaatgt ttttttcttc tgtaaggttt cgtaagagac
     1981 ctctgtaatc atcaaatttt tgtctattga tctcagaatt tttttgatag aaccattcat
     2041 aaagcatatc gttctctcag ttgtttattt tgtggtgatt taatcataca agaaaacgat
     2101 atgttttttt ataaaaacat gaataggaaa aatagttgac aagaaaatga caacgccata
     2161 tgatgttcca tagtatttac aacctgtcat agatgactgt aaaaaataaa agtaaaaaga
     2221 aaggacgaca acaggtggat ttttatcagt ctctacaact agatccgttt attttaaaac
     2281 aaaaaatacg agaagcagct tctaaaaaag aaaagtgcat gtatatttgt tcattgtttt
     2341 tacgatcatt attcatcgta ttgtttgcca tttgttttat cattataatt acaacattat
     2401 ttgaatcgaa gcataaacca tacgctgtgg ttttattctg tatgttgatg agtattcgtt
     2461 ttgttgactt tggttataag atttcccatt cgatcatagg tttagcaatc gtcatgttct
     2521 cactattagt agcaccgtat gtccagctga tcaaatggtc agttatgggc atgttgattc
     2581 attttatttt actaagcagc atattaatgg caaccgctag tgatcccaaa atggggaatg
     2641 cttctttgta cggcttttca tatctcttta ttgtttattc gttacctaaa gattcgttga
     2701 acaagaattt ctttacacaa acaagtagct tattattttt gtttttttgt tggttttcag
     2761 ttctccttta cagaaaacat cgagaaaaga acaaagacaa aagcttgttt aaagagattt
     2821 ttttgaaagg catgtattcg caggaaaaaa tttggatgct catctatgca tttggcatta
     2881 gtcttttgat cgttgcagga gagtatgtcc cttttcagcg attgatgtgg gcagggtttg
     2941 cattttcttc tattgtatct agctatggat tgatgtcgat tggtttcaaa gaacgagcag
     3001 tagaccgaat cattggctca ttgattggat gtgttttatt tattggtatc agccaattta
     3061 ttccttttaa ctgggtcggt atattaggtg gtctagcttt aggtgtttgt tctacctata
     3121 gatataaaac agtttttaat tcttttggtg ctttggcaat cactgccagt ttattcgggg
     3181 ttccaggagc agtaacgatc cgcatttttg agaatatcct tggggtatgt ttaggaatca
     3241 tgtatattgg ggtgactgaa atacttatcc gaaaaataag agaaaaacac ggtttgaatc
     3301 attagatgag atcgaataaa aaataaggaa aaagtgaaga tacacatgga tgataaattg
     3361 ctatcattcc atgtgtatct ttttacggta aatcagtgaa acgttcgact ttcattttta
     3421 atttatactt tttacggagt tcgtttattt gagccatcat ttcggatttg tgatgctttt
     3481 cgattgcttc ttcatctttc caacggtcga tcagtaaaag agattctgga tcttctagtg
     3541 gaaagtaata gtcatatttc tcgtttcctt cttctgcacg aatcgctttg acaatgtttc
     3601 tttcgaccat ttcttctgca aattttctgg cttgtccatt tgtacttgta tacaaaatat
     3661 tcactgtgat actcactaaa tcccctcctg aaaaaattct atcactagta tatcacggtg
     3721 ccagaaatta ttattcaaga tatgatacac attttttccg caatgctacg gaaatatata
     3781 ttttgaatag aaaacgctta caagatatgc ttggtttata aaaataaaag gagtgattga
     3841 tttatgaaaa aagcattgat tatttgtgcg gcaggaatgt catcctcgat gatggcctca
     3901 aagacaacgg atttctttaa gcaaaaaaga gaagaggtac tcgtagatgc agtttcagct
     3961 acagaaggcg ataatatgat taagaatagt gattttgatt tatttctgat cagcccgcaa
     4021 acgacgatgt ttttggataa attcaaaaaa ttaggagaat ctgttggaaa gcctgttgtt
     4081 agtatccctt tccaagcgta tgtcccaatc cctacaggca tccagaagtt agcagaggtg
     4141 atcgaagaga acatatgatg gaataggagt ggatgataat gaaacagaag gaaaaattgc
     4201 tgttgagata tttgattgat cacaagaagg agtatgtcac cagtcaacgt ttagcttctg
     4261 aattgttatt atctgatcgg acaatccgta attacttgca gcggatcaaa gagttagtag
     4321 aaaaaaacgg aggtaagatc attgctaaac caggttatgg ctaccaactg catattttac
     4381 aaagactgac atttgacttg tttttgagtc ggcaagaaat agtacctgga tatgctagag
     4441 aaccgcaagg attttatgag tccgaagatc gacaaaagta tatattgaac caattgcttt
     4501 tggaagatgc cattcttttt atggatgatt tggcagaaga gctttatatc agtcgttcca
     4561 gtttgacaaa ggacatgcaa gaaatcaagg agcgattgat tccatattca ctaaaaatcg
     4621 tttctaagca tggtcaaggg acatggatcg aaggggaaga aagaaatcga cggcatttta
     4681 tcatggatac tttttttgga aaccattatg gaaattcatt gaaagaatat ttagggcaaa
     4741 gccgtttttt cccagacatc agttttgaag agctagtcat tatcattctc gatgaaacaa
     4801 gagaagctaa gttaaaagtt tcggatttta tcatacagaa tctgacttta cacttggctt
     4861 tggggatcaa acggctccga gaagggtttg aaatcaagga attaggcatc gaacaagaag
     4921 tttctaagcg agtagagtat caagtggcgc agcggatcgt tcaacgtatt gaggtaatcg
     4981 caggtgtatc gtttcccgaa gaagaaattg cttatttgac attacatctc atggctaagt
     5041 cgaatcacaa agaaaatcaa aatgatcagg aactatcaaa ggaattagcg aaagttctga
     5101 aaagattgtc tcaggaattt catttttcat tagtagagga tctccagctt ttcaatggac
     5161 tactcgatca tttgtcaccg atgatgattc gattgagccg aggtattcgc attgagaacc
     5221 cattgactga ggagataaag aaagaaaatc ccaaagtctt tgacgcagta aaaaggcatt
     5281 tcagcaacat gccggctttg aaaaactata ccatcaatga agatgaatgg gcctatttgg
     5341 ctttgcatct catggcggca ttggaaaaag aaagagctgc gcataaacta catgcattga
     5401 ttatctgtgc aacgggttac ggcagtgccc aactattaaa gaatcgcgta gtcagtgaat
     5461 tcggtaaaaa tattacagtg gtaagtgtaa aaggctatta tgagatcaat gaaacaactt
     5521 taaaaggaat cgacctgatt atttcttcta ttgatctttc gacaatgttt ttcaaaattc
     5581 cagttttaca tgtcagtatt tttttgaatg aagatgatgt tcgtaaaata cgaaaggtag
     5641 ttggagaatc tataccctat cattcctcag atagaccgat accagcattt tctctacagc
     5701 aaaaaaagca gatttacacc gaacagttgt ctgaaaaatt tttcaagact tatacgtacg
     5761 aaccgaaaaa ggaagaaatt cttcatgatt tgctgcaaaa gctgagcata aatgaagaag
     5821 aaggatatat aagagaaatg cgaaagcaga tccagcaacg tgaaaatatg ggacaaatca
     5881 tattcagtga tacagtggca gtcccacatc ccgctgttcc agttggaatc gaaacaaagg
     5941 tagccgttgc attgattcct tctgggatgc agtgggatca atatcaagaa attcattttg
     6001 tttttttagt ttcgccttct tatgtcgaaa atgaaggaat tacggtcgtg actaaagcaa
     6061 tcgttaggtt agttgaccag ctaaaagtac agcaggaaat cttagctgaa cctatttttg
     6121 agaatttcag cagtaaattt atcaaactga tcgaataagg aggaaaacag atggctgaaa
     6181 aaataaacag tgaaacacta caagtgactt cttttgatat cattttccat agcggaaatg
     6241 cacggacact gatacatgaa gcatttcgct cgatgcgtaa agagatgttt gaagaagtag
     6301 aagagaagtt gcgacaagca aatgaagaga ttcttcatgc gcatcagtca caaactcaac
     6361 ttctgaaaga atatgccagc gggacaaaaa tagaaatgga aattatcatg gtccatgcac
     6421 aagatcatct gatgacgacg atgacattat tggaagttgc acaggaaatg aattatttgt
     6481 atcaaaaaaa taaatagaaa ggaaggatca ttgtgcagga tacagtaaaa aggaaaatcg
     6541 aattagaaaa aaagcaactt agtttgaaaa acatgtattt caatcgttat ctaatcgtac
     6601 gttacctgac tgcctttttc tttttcatga acatgcaatg gatgattctg cttctatcag
     6661 ctaaaagttt aggaagtagt ttaccgatga ttctgatttt agctattttg cctgcagtag
     6721 gagaacaagt aaagctttat cgaaaacacc aaacgaacgt tccatggaca aagtggtatt
     6781 ttttgttcca gagtgtcttt aatttattag tgattccagt gttgtttacc tcaggattta
     6841 cattcttgta tccttttatg gcaaataaca atggaggaca gttatttgtt ttcattcttg
     6901 ttgtaagcgg tatttttgcc agtgcattta tacagtatcg tttaaagaaa atttcactca
     6961 accaagacca acagtatatc cgtattaaac aatatgaaaa agcgttatat ttaggaaagg
     7021 agaataacta atgtttgatt ttttgcagaa atacctgatg ggacctatgg ggaaaattgc
     7081 gcaacttaaa atcgttcggg ctgtcatggc agcggggatg gcttctattc ctttcacgat
     7141 tgtaggctcg atgtttttgg ttttaaatat tttgccatta ccgttcccat ttttagaagg
     7201 attttttaat gcaacttttt tcaaagttag tgacttgtac atgatcgtca atacaatgac
     7261 gatggggatt ttatctattt actttgccat tgtgtttgct tatgaattaa cgtcaattga
     7321 acgagatgaa caaaaattaa atgttaatcc gctcacgggg gcattactat ctgtttttgc
     7381 attctttatg tgtatccctg aattgatcat gactgatggt aaaatcagct tgattgcttc
     7441 tatcaatgag acagaaactg tagtaaatgg tattaggatg ggctcttttg tcgaacgttt
     7501 aggaacttca ggaatcttta cagctattat tatgtcgatt attgcggtcg aattgtattg
     7561 tatgtgtgtc aagagaaatt gggtcataaa aatgccagat gttgttccgc caggagtttc
     7621 tcgttctttc actgctctga tcccaacatt tgtcattgcg tttgtggtga tgatcatcaa
     7681 tggattatta gttgcactag gaacggatat cttcaaaatg attgctatcc catttgggtt
     7741 tgttacgcag ttgacgaata catggcttgg tgtcatggtg atttatttct tgatccatgc
     7801 attgtggatc gtagggatcc atggagcgaa tatcatcact tctttcttga ccccgatcgt
     7861 attagctaat atggcagcta acgcacaagg cgcaaattat ccgttggcag gagaattcaa
     7921 caattcttat gtaaccgttg gtggatcagg tgcgacttta ggattgatca tctttattgc
     7981 attcctcgcg aaatctgatc agctgaaagt gttaggaaaa gcctcacttg taccaggatt
     8041 attcaatatc aatgaaccaa tcattttcgg gatgccaatc gtctacaatc cctatttagc
     8101 ggttccgttt ttcttagctc cgatggcttc tgctacactc gcttattttg ccattcggct
     8161 ggaaatcgtc aaaccgatgc ttgcacagat gccgtggcct tcaccagtcg ggatcggagc
     8221 atttgttggt agtggtggtg attggaaagc tgctgtgtta gcagtcattt gtgcaatcat
     8281 cgcattcatt atctggttcc catttatcaa attctatgat aataaattat taaatgaaga
     8341 aagagaaaag gcagcagaat tagctagtga aaagttaaaa tgatttctaa gaaaaaagga
     8401 actgtgacaa aaaatcacag tccctttttt tcttagaaat gggaaaccac tagtatataa
     8461 ataccattat tcttcaatca accgcttcac gattgcataa tccccttcat aaggttcatc
     8521 tacaccattg attttttgat agggatccac gccttttccc gcaataacga ctgaatcttg
     8581 cggagcgctt tctgctaaag cgcgtcgaat cgcttcagga cgatccattt cataatgaac
     8641 gatcaaatct ggattagtaa ttgcttcatt gatttcttcc gcgatttttt tcggatcttc
     8701 aaatgctggg tcatctgccg tcaaaaaggc gatgtcagct gtttctgata gcacttttcc
     8761 aaaatcatgt cgacgggaga ttgctttgtt tcctgggctg cctaatacaa caattacacg
     8821 gccatctgga tgttcatttt tggcaaattt cagcaatgtt ttcaagctta gataattatg
     8881 tgcatagtcc acatagacat gcgctccatt ggattggatc aattgatcca ttcggcctgg
     8941 tacacgagct tcttttaatc cgtcttgtgc atcttgactg gaggcacctg ttagtgctgc
     9001 ggcaatgatc gcactggctg cattttcttg gttgaatcct ccagccagca aaatatcata
     9061 agcagtatcg cagatagcta agcgatcttc atgagaagat aaagtaaaac cgtgagtacc
     9121 tttatctgaa cggatcactt gataattgct ttcttccgaa cgaccataag tgatcgttgg
     9181 aatctggaat agatcggctg tttccctaag taaatcaaaa tagtcacttt catgatttaa
     9241 aacaactgtt tttgaattca agatcaattg tcgcttgcaa tagaaatagt catcaaatgt
     9301 cggatgttcg atcggactga tatggtcagg cgagatattc aagaagattc cgacatctaa
     9361 agtcaagccg tatacgcgtt gtgttttgta agcttgtgaa gaaacttcca tcactagatg
     9421 agtcatacca ttttcaactg cttctgacat catacgatat aaatctaatg actcaggcgt
     9481 tgtcaaatgg gatttgaaat atgttttgcc atctaacgtt gtattcatag tagaaagcaa
     9541 tgctgttttt ttatttgttg tgtgatccaa gattgctttt gtaaagtacg cagcagttgt
     9601 tttacctttt gttccagtga atccgatcac tttcaattta ttttgcggat agtcgtaaaa
     9661 agccatagca agaagcgcca ttgctttacg gatatccgtt acgatgattc ctactgctga
     9721 attttcgtat ggttgttctg atacataata ttgaataccc tgttcgattg ctgaatccaa
     9781 atattcttct ttgaaattca ttcctttaca gaaaaacaaa gtagaagcat cagcttttct
     9841 tgaatcataa cttaactgaa gaaattcagc tttttctggt acatcaagat gccagcctct
     9901 tgttgaaaca aattctttta atagattttc ttttaatagt aaatgacgga tgtcttctaa
     9961 agagaagctc attgattgat ccctcgcttt attcaatttc ttggtttatt atagcacact
    10021 ctttttaata tatcgtttgt ttccgctatg acaaaatcca gctttattca aattttcttg
    10081 acacagggga caagcggatg agtattttca taaacaatga actgactgta atagatagga
    10141 gaacgaatag tgtctccaac aatccaaaaa cataataatt caaaaagacg ataagactat
    10201 tggtaagtaa aagtccttgc ggcattggaa gccgaaaaaa tttgtggaaa ataatcggcg
    10261 gtatcgttat accgccattt gaggccccga ctgtgtacaa tgtgtaaacc ccaagactga
    10321 acaaaagact tcctgaaatc agtgaaaaga aatgtgagga gatcatttcc acttttggaa
    10381 caatctctaa aacaacagga aaaagcagac ttcccgctac agtcttaaaa aatactgatt
    10441 ttcctaatag gacagcggct agaagcagca tcataagatt gatgctccaa acagtaactg
    10501 agcgttggat agaaaaggcc gtttcaacta aatgtccgat ggcgcccact ccggcggaag
    10561 ctatatcgtg agggagcaag aaccaattca atccaactgt gataaagaaa agacctaaaa
    10621 atataacggg tagttttttt atttcttgtg tcattgatat ctcctataaa tgttagccat
    10681 aaaaggctgt atatttcttt actttaccaa aaaaacgaaa ccgaattcaa aaaaacaatt
    10741 gttcttataa aagttatata aaatcgattg ccagtttctg ttttaccaat taaaatgata
    10801 gtaatgtttt gtagaaagtt ggaatctgac cgatggataa tcaaagaaaa ccagcattag
    10861 atcaattaac accgcaagaa aaaatggcac gaggctctgc ttggatgacc gccagtaata
    10921 tcatttcaag attgctaggc gctgtctata tcattccctg gtatgcttgg atgggcgaaa
    10981 atgctaaggc tgccaatgga ttattcaata tgggatacaa tatatatgca ttgtttctac
    11041 tgatctctac agcaggaata cctgctgcga ttgcaaaaca aactgcacgc tataattcat
    11101 tgaatgaata tggcacttca cgacgattat ttatccgtgc attacagatg atgggcgggt
    11161 taggcctgtt gtttgctttg ttcatgtaca tcgcctctcc ttggctagct catgcttctg
    11221 gtggcggaga agaactgatt ccaacgatgc gttctttgag tatcgctgta ttggtttttc
    11281 cttgtatgag tgtgatacga gggtatttgc aaggcaatca agaaatgatg ccttatgcgc
    11341 tgtcgcagat tgtagaacag gtggcacgta ttttttatat gctattggct acattcatca
    11401 tcatgaaagt catggatggt gactatgtga cggcggtcac gcaatcaact ttcgcggcat
    11461 ttatcggtat gctagcaagt attcttgtcc ttttgtattt tttgaagaaa catcaagcgt
    11521 atacatcggc gtttattcac tacagcgaaa acaaaataaa tattgcaacg aaggaattgt
    11581 tgttagatac cgttaaagaa gcgattccgt ttattattgt gggttcaggg gtaacgatct
    11641 tcaaattagt cgatcagttc acttttatga agatcatgtc tgcatccacc gagtattcca
    11701 atgcacagtt actggatctt ttttcgattt ttagtgccaa tccagataag ttgacgatgg
    11761 tagttattgc attggcaaca tcgatcgcgt ctactgggtt accgttgatt acagaagctg
    11821 ttacgttgaa agatcgagta ggtctggcaa aattgacaag cggaaattta cagttgtttt
    11881 cattttttat gtttccggcg acatttggtg ttatgttact tgcctatccg ctaaatacat
    11941 tattttatac accggattct ctaggaagta atgtactgat ccaagcaagt tttgtaggac
    12001 tcttcctagg actatatatg ctagtttcca acatgctgca aggaatgttt gaaaacaagg
    12061 cggcaattaa ttatttggtt attgggtttc tagtgaaact ccttcttcaa tacccagcca
    12121 ttcgtttatt tgaagtatac ggccctttat tggcgacaat gatcggattt gctgtgtctt
    12181 gtaccttgat cttaaagaga atccatgaag tagcccgctt taaaccaagt tttgtctggc
    12241 gcaggacatt gctgatcttt attcttacct tgattatgct tttggcttcg tggatcacaa
    12301 agatgatttt tggtgctttt ttaaacgaag atagcaaatt ccagtctcta ttgttgattc
    12361 ttgtagtagc aggtataggg gctttagtgt atggttattt agctttgaaa atccgcttgg
    12421 cagaaagact actaggacca ggaatagcgc gtttacgaca taaattaaaa ataaaataag
    12481 tgaatcagaa gagctagatt gatgctcttt tgaaatgggg gaaacgcatg cgtttagata
    12541 agtttttagc agatatggga cttggcagcc gcaaagaagt caaaggatta atcaaaaaag
    12601 gaacgatcga agtcaatgga caagtggtga aaagcgataa agcgcaagta aatgaattcg
    12661 aagatgcggt tacttattta ggagaaatca ttacgtatca aaaagatttt tactacattt
    12721 tgcataaacc tgcaggagtc atttctgcta ctcaggataa tcatgatcaa accgtaatcg
    12781 atttattgga agaccaggat tatcgggaag atctttttcc agtcggccga ttagataaag
    12841 acacagaggg cctcttgatt ttaacgaatg acggggtgtt tgcccatcag ttactatcac
    12901 ctaaaaaaca tgtggagaaa gaatatctag ctgaggttag cggtataatg acagaagaag
    12961 atatccgttt atttgcagaa ggactgatta ttgatggcga tgagcagaca ttgccggcaa
    13021 aactccaaat tgatcaagta gatcaagaga cagaaacttc aattatccgt ctgattttgc
    13081 atgaaggaaa gtttcaccaa gttaagcgaa tggtcaaagc agtaggaaaa gaagtcttat
    13141 atttaaaaag aatccgtatg ggaaaatttt ggctgcctaa agatttgaat aaagggcaat
    13201 atcgacccat gaccaaagaa gagctagaac aagtgagaga aaaataattg aatggatagc
    13261 taaaagaata agcagagtag ttgtagcgcc atctgaaaag cagacttgtc cgtctgactt
    13321 tcggatggct tttttgtgaa atttcggctt atttccgtag aagctacttc tggaacaccg
    13381 tttgttcgga ataagggact gtgacaagac ttttgttaca gtccccattg ttccttgtga
    13441 ctcagagtta gatagtaagg acacgatctc cctaatactc aggccaaaac gctgaattca
    13501 caacctctga taaacggtgt tcaatcagct gaccctcggt attagctcaa aaaacggcaa
    13561 aatatgagga actattttcc cgtttttttc tctaatactc aggccaaaac gctgatttca
    13621 caacctctcc tatactttgt ttcattttcc ctatactttg tttatttatt ctcattattg
    13681 aaagcgctat aattacgttg cgaatgaatc gaaaggggtt tttagatgaa aaaacgaaag
    13741 gggttcaatc atttttttat gaatctatgg cgttataaag cacttgtcct gatggctgta
    13801 ccgggtatgc tttggatgat ttttttcttt tacatacctg taatggcgaa tgtcgtagca
    13861 ttcaaaaatt ttcatatttc agcagatggg ttcttggcta gcttgaggga aagtccttgg
    13921 gtgggttggg aaaatttcaa atttttattt tcttcggatc aagcatttct catcactaaa
    13981 aatacaattt tatataatgt agcatttatc cttttgaatc tgctgatctc agtcgtattt
    14041 gcaatcatta tgagcgagtt gagaaataaa cgactcgtta aagtttatca aacgatgtcc
    14101 ttactacctt attttctatc ttgggtcatt atcagttact ttgtttacgc ttttttaagt
    14161 cctgacaaag gaatattcaa tcagtggatc actggacatg gaggagaagc tgtcaattgg
    14221 tataatgaac cgaaatattg gccgtttatc ttggtgttca ttggtacatg gaaagggatt
    14281 ggttataaca gcattattta ctttgcatct gttatgggaa tcgatccgac ttattatgaa
    14341 gctgctatgg ttgatggagc tagcaaatgg cagcagatca aacatgtgac gataccacaa
    14401 cttattccac taatgacgat tttaacgatt ttagccgtag gaaacatttt ccgagctgat
    14461 tttggcctgt tttataacat tcctaggaat tccggtgcat tatatgatgt gactcaagtt
    14521 ttggatacgt atatctacaa tggcctgaca tccacaggag attttggtat gacggctgct
    14581 gcaggacttt accaatcagt tgtcggcttt gtcttgttga tgatcacaaa tacgatcgcc
    14641 cgacgttttg atagcgattc tgcattattc taaggaggaa aaaaatgaaa aaaaagaaag
    14701 tggagagagt ccaagtccgc tctttcaata agacggctaa ttttttctct aatataatga
    14761 ttgcactctt tgctatttcc tgtattttgc catttatatt tgttatcgcc atctctttta
    14821 ccgatgagtc catattgtcg actcacgggt acagtttttg gccagaaaag ttcagtatat
    14881 ttggttatac gtacttgttc gaccagatgc aggataaaat tttccaagcg cttttcgtca
    14941 ctgtacttgt tactgtttta ggtacactga tcaatagcac ggctacttct ttatatgctt
    15001 atgcgatttc acggtcaaac tttccattcc gtcgtttttt taccgttttt tgtttgatta
    15061 cgatgttgtt ctcaccaggg atggtggcca attatcttgt tatgacaaat cttcttcagt
    15121 taaaagatac gatttgggca ttgatcttgc caatggctgt cagtcccttc aatattattg
    15181 tgatgcgcac attctttaaa cgttcggtct ctgattcgat tattgaatcg gcacggatcg
    15241 atggagctag cgaactgcga atatttgttc agatcgtttt accgttagct gttccaggta
    15301 ttgcgacaat cagtttattt gccgcattgg gttactggaa tgactggttc aatgctttac
    15361 tctacatcca agatgataag ctagttccac tacagtatct tttgatgaaa atccaaagta
    15421 atattcaata tctgacacaa aattcaggag caggaagcca attgacaggc ggattagcct
    15481 cagttccagg agaatctgcc agaatggcga tcgtagtcat ctcgacgttg cctattgcga
    15541 tcagctatcc atttttccag aagcattttg tcaaaggtct aacaatcggc ggagtaaaag
    15601 aataaagaaa caaaaatata aatcataaaa ttaggaggaa gaaaaatgaa gttatggaag
    15661 aaactagcct ttacaggtgt ttcagcgttg ttgttgggaa cattagcagc atgcggaggt
    15721 tctggttcta aagaccaggc agaagctagc aattcggaca ctttgcagat gtatcaaatc
    15781 ggagataaac cagataattt cgatcaattg atggaagtag caaacaaacg aatcgaaaaa
    15841 gagatcggtg taaaagtcaa tatcaattac attggctggg gcgattacga aaagaaaatg
    15901 aacgtcatca tttcttccgg ggaaaattat gatatcgcct ttgcgaacaa ctatgtttcc
    15961 aatgcccaaa aaggagcctt tgctgatttg actgaattag cgcctaagta cgctgaaaaa
    16021 gcttataatg atttagatga agcatatatt aaaggaaatc tggtcaatgg aaaattatat
    16081 gctttcccag tcaatggaaa tgtctttgct caacaagtac ttacttttaa caaagcttta
    16141 ctagataaat acgatctttc aattgatgga atccaatctt acgctgatgc agaaaaagtc
    16201 ttgaaggaat tccatgaaaa agaaccaaac acggcagctt ttgccattgg acaaggcttc
    16261 aaagtccaag ggaactttga ttatccttta gggaatacgt taccatttgc tattgatctg
    16321 gatggagatg attcgaaaat catcaaccaa tacgataatg aaacgtatat cggactgtta
    16381 cgtacaatgc atagctggta caaacaagga ctcattccaa gtgacgctgc aacgagcaat
    16441 aaggattatc cactagaagg aaatacttgg ctaatgcgtg gagaaacaca aggaccgtat
    16501 gattatggcg atacaatttt gacaaatgca gcaaaacaag aacttgtctc aaaagcaatt
    16561 actgttccac taaaatctac agctcaagca caaatggcaa attttgtcgt atcaaatact
    16621 tcaaaaaata aagaaaaatc agtagaactt ctagggctgc ttaacagtga tccagaatta
    16681 ttgaatgggc ttgtttgggg gatcgaggga gaagcatggg aaaaagtcga tggttcagat
    16741 gataaaatca aattgctaga tggttatcag ccaaatacac atatgtctgc ttggaataca
    16801 ggaaacaaca agattctata tacacaagag tctattacgg atgacatgat tgccaaacgt
    16861 gatcaatcga ttgctgatgc agaaacttca ccgattttag gattcagctt caacactgac
    16921 agtgtcaaaa cagaattaag taatatttct aatgtcatga atcaatattt agatggattg
    16981 aatacaggga ctgttgatcc agatgaaaca ttaccgaaat tgaaagacgc tttggacaag
    17041 gctggctatg ataaggtatt gaaagaaatg caaaaacaat atgatgagtt ccgacaagaa
    17101 taataatgaa taaagacaaa ggggttgtga caaaagacgt gtcacaacct cttgttccga
    17161 ataaacggtg ttcaaaagcc agtttctcgg tattaagcta aatatatgta aaaatgtgga
    17221 aagccatatt cacaaaattt ttcttactac tcgaaactaa gcggctattt cacaaactct
    17281 tggtaaacgg tgttcaatca gctgaccctc ggtattcgct cacaaaacga caaaatatga
    17341 ggaactattt ttccgtttgt ttctctaata atcaggtcaa ggtgctgatt gcccaacctt
    17401 tttttgtata atgagaaagt ataaacttaa tgtttggagg agaagatatg ttagggaagg
    17461 ttttggaaga gttatttatc cggatctggg tcattataaa actaaccttg tatttctgga
    17521 tatatacatt tgccggcggg atcatctttg gattaggtgc ggcatggaaa acagtcaatg
    17581 aactatttta tttgtacgga ttcgagtata aagaaatcac aataaaaaga ggctggaata
    17641 tatataaaag aaatttttta agaggcaatc tgctatttag tttattttta tctggtactg
    17701 ctttattgag ttacaattta tatttatctg ttcaaatcaa agggctcatt tttttagcta
    17761 ttgattttat tttacttttt gccttgctct gcctatttgc tacttatcaa tacagtatga
    17821 ttttagatag tgaatatacg atctctgttc ctaatctgct aaagctaagt tttatttcgg
    17881 ttttttccag cttttcgtct tttctaaaaa taattattgg tagcggtata attttaggcg
    17941 tgacttggca attcaaagga ttgatcctgt ttggtgtcat tggtcttttg acggtttgga
    18001 atggtacgat gacaacacat tggcgtgaag aattagataa acagttggaa agttatgaat
    18061 aagtttcgga ttctattttc aaaaggaacc ttactaaatc gtctgttgcg gaaatacgcg
    18121 gttatcatga tcggtgtaac gatgactgct accgttattt ttagtatcca tacttgggaa
    18181 caaaatcaaa aacaggcaga aaacatgaca agtgatgccg ttcaaagcac aagcagaatg
    18241 ctgaatgata aaacaacctt gagtaggatc atcaaaaacc agcttgtagg gaattccgaa
    18301 aagatcgaaa atgtgacgac ctacttaaca aaacccatag atcagtatct gatgtatgta
    18361 tacgaacagc aaaacagtac cgatgaatta gtttctttcc caaatcaaat caaagatctc
    18421 tacgcaaatt atgaagaact aagtgcgata tatatcgtgt tgaatcaact accggagtat
    18481 tatgaatctt ctagagaaaa caaaggtggg gaaataaaaa aggggacacc aaaattacta
    18541 gacgcctttt atatcaagtt gcctatcaca caaggaggag ctgagtcagg aagtattttt
    18601 attggttttc aaaagaaaga actagatatg attttagaaa atctaacgtc attcaatgga
    18661 ctctctttat acatgatttc tggaacgaca aatcgactat acacattcca tgataataaa
    18721 atagctaaag aaacgtttga aagacaagaa atgatcatca cagagagtct gaagaaaaat
    18781 tcacaattgc cgattgacga tctggaaaaa aacaattttg ttcaacacca agaactgtct
    18841 gatgattatc gtatattagc tgtactagat aaaaaaagtg taaaaatcga aacgggaaaa
    18901 aatcttgccc cgctgatcat tggtatcatt attttagaca atatactgct tatctttctt
    18961 tataaaacat tcaaacgata ttcacagcaa gtatctatcg tcatgcaggc catggatcaa
    19021 acagcagcag ggaatttaga gacgcggatc gacataacaa acacggaata tgaactgaag
    19081 gaactttcaa tcggtatcaa cgaaatgttg gatagcatca atcagtttgt agaagacatc
    19141 tacaaattag aaatcaaaca gcaagacgca catatgcggg cgcttcaagc acagatcaat
    19201 ccacactttt tatataatac attagaatat atccgaatgt atgcaatcag cgaaggaagt
    19261 gaagaattag cagatgttgt gtatgcgttt tccgctttgc ttcgaaacaa tacgaatcaa
    19321 gagaaaacga tcactttaaa agaagaactg gacttttgcg aaaaatatgt ctatttgtat
    19381 caaatgcgtt atcctaatcg agtagcctat cattttatga tcgatcctga tttggaaaag
    19441 atcgaagtac ctaaatttgt gatccagcca ttagttgaaa attattttaa acacggtatt
    19501 gattttactc gattcgataa tgcgctaagt gtcaaagtct tgcaggaagg caaacgggta
    19561 aggatcatca tcaaagataa tggaaaaggg atgactgaaa aacggctaaa acagattgaa
    19621 gaaaaactgt ctcatcctaa agtggaactt cacggttcta tcggtctgca aaacgtgaat
    19681 gaacgtttac gtgccagctt cggcagcagt tattatatgt cgcttgagaa taatgagaca
    19741 ggtggactga ccgtttctat tacattcaag gagggatgag cgtgtatcaa gtgttattgg
    19801 tagatgatga atacatgatt ttgaatgggt taaaaaagat aattgattgg caaagtttag
    19861 gctttcaaat agtagcaaca gcagagaatg ccaaagaagg actagctgta cttgaacagc
    19921 gacagattga tttagtagta acggatgtga caatgccaga aataaatgga ctggaattta
    19981 ttgaagcggc tcaaaaagaa cgtcataatt ttgaatttat gattttatca ggataccaag
    20041 aattcgatta tttgaaagga ggtatgcaat taggcgccgt gaattatttg atgaaacccg
    20101 tgaataagtt cgaattggtt gaaagcctca agaaaatcaa aacacggtta gatcagcaaa
    20161 atgaacaaaa aaatcaacaa gaaatctatc aagaactgtt attcagtcaa tggttgaatg
    20221 aagaattgga tgaaataagt gaagaagaaa taataggaca aataagtgag aagcagcata
    20281 ggatagtatt gattcaactg gcaagaactc atgatactct tatcaataga tggttgcaag
    20341 aacggcaaca aatcttttac tatcaacgaa attacggaga ccgtgtattg atcacgttgt
    20401 tgttggaggc agatgaagtt gatggcttct gttgttttgt tcaagaaaac tttcctgatc
    20461 aggaatggct gatcagtatc ggggaagaga cagattcttt ggacaaaatc cctgaaacat
    20521 tccaacaagc gaaagacaat ctacagttgc atcaatttta tggagataaa gacgagcatg
    20581 ttttttacgc agtacaagca gaaacaaaag atcaaaccat cgatttttca agtttcagac
    20641 gcgtgctgca aaataaacaa ttggaagtcg ctcaaaaaat gatcactgat ttttttgaac
    20701 agtttcagtt agcagccatg atgccggaag atatacgata ttccagtttt ttactgttta
    20761 tggagattca acgggaattg attgatctgg aagatgagga atatttacaa ggaatcgaaa
    20821 aaatccatca ggcaaaaacg gtgcaagaac ttcagcagct acttctgtca ttcatcaaaa
    20881 agcatcagag acagaaaaag tacagtgaca atgtggaaaa agtaatcgta atcctgcacc
    20941 agcattatca agaaccactt acactcaaag aagtgtcaga aaacctgcat ttaaatgtca
    21001 tgtatctagg acagctgttc aaaaaagaaa cgaaaaaaag tttttcagct tatttgaacc
    21061 atttacgtat ggaaaaagcg aaacaactgc ttttgcacag taatcaaaac atcaatgaga
    21121 tagcaagtga gattggctac aacaacacca cgtatttctc taaattattc aagaaaatcg
    21181 tcggcagatc ccctaaagag taccgagaaa acagtggaga atcataaaaa aaaagccaat
    21241 gtaatgaaat aacttataaa aaattgtcta gaaatctaat tttgggctgt tcttattact
    21301 tgaggcaagg cagctttttc atgacctctc gataaacgga gttcaaaagc cagtttctcg
    21361 gtattaagcc aaatttatgc aaaaatgtgg aaagccattt tcacaaaatt tttcttaata
    21421 ctcgaaacta aacagctttt tcacgacctc tccactaaat ggtgttcaat cagctgaccc
    21481 tcggtattag ctcaaaaaat ggcaaaatat gaggaactat tttgccattt gtctctctaa
    21541 tactcaggtc agaacgctga tttcacaacc tctcaataaa cggtgttcaa aagcttgcat
    21601 ctgcggtaat aagaccaacc aaacgaaaaa tatgaggatc tatttttgct tggctgttct
    21661 tattacttga tgcaggacag ctttttcaca acctcttgtt aattatagtt tgataaggaa
    21721 aaaggcaaat cttttgcttg atatttctta gggtgaggga tgatccctaa ttggtaagag
    21781 atcgtgccgc ctttcagcaa atcttgatgg gtaaaatata atttcgtata ttctctgtcc
    21841 atccgtttga ttttatggat aaattgttgc tgcggccgat taggcgttgc ttcaatcgtc
    21901 aattcctttc catttgacaa aagcaaaaca gccttgtcaa ttaatggcat accgataaca
    21961 tattcaccgg ttccaggcgt gacaggataa aatcccagac tattgaagat ataccaagcg
    22021 gccatacttc cattgtcctc atctccaggg taacccattg gagaatcgtc gaaggtctga
    22081 gtcatcaact gtttaagcag tggctgtgcc atttcaggtt gtcctatata actgaacaag
    22141 taaggatagt gaaaacttgg ctggtttgaa atagctaatt gtccaaattc tatcgcggcc
    22201 atctcactca tttcgtggat ctcaaaacca tatcctcctg ggtcaaacgt tgggggctga
    22261 ttgcacagct caatgagttt ttctttatat ctctcactgc caccatattt tccgatcagt
    22321 cctgaaaaat cgtgataaac agcaaagctg ctttgccaag cacttccttc tgcataatct
    22381 tgtccccaac gattagctga aaatggttct ctgaacttgc catctttatc ttttgaacgc
    22441 ataaatcctg actcatagtc aaagatattt tgatagttca atgattgctg ctgatatttc
    22501 ttcgtcattt cctcttcttc tagtaccttg gcaacttggc taatacaaaa atcgctataa
    22561 gcatagtcta atgtgtgatt gactgattcg tggtagtgat taggaacata gccatatgtc
    22621 aagtaatctt ctgttccttg gcgtccataa tttggatgtt tgctttgaac cgtagcacct
    22681 ttttccattg ccgttagaaa ttcaggcatc aagtctcgtc ggatatcttt tacagcagca
    22741 tctgcaatga ccgcatcgat caatgtccca ggcataagtc cacgttcatc aggagacagc
    22801 cattttggca aatagccact ttctctatag ctgttcaaaa aaccttccag catttcttcg
    22861 tatttttcta cagcaatcaa agaataaaga ggataaaccg ttttatacgt atcccaaaac
    22921 ccattatttg tatagagaac accaggtttt atagatcgac tagtcgtatc atagtggatt
    22981 ttttgcccac taggatcaat ttcataaaat gtttgtggaa ataaaaacac ccgatataaa
    23041 ttatgataaa acgtccgcaa ttgttgttga tcatggtgtg tgagctgtat acgatcaaaa
    23101 taggactgcc attgttcttg actgtgagca aggtaagtct ctttgctttg gttttgttct
    23161 agttccaggt tataagctgc ttgttccgag ctgataaaag atgtcccaaa tcggatagtt
    23221 tgtttttttg tctgttcaaa atacaacggg atcgagtcgc tatttttgtt ggaaacagct
    23281 aactcatcaa ttgttaaagg atattcaaat ctcaatataa aataaaaaga aaaatcagga
    23341 tcttctgaac cagcaaaatg tgtgattttt ccttccactg tgtaaggatc tataacaaag
    23401 agctgatggc gtcccggaaa ggataaaagt aaaccgctgt catttttgct gtaatcaata
    23461 gataagattc cgccatacat gctaggtatc aatgtagaac agatgccata acgtaattga
    23521 cagatcgaca gatgagtcgg gcaaaatata ctttcttctg ggcggtaaga actttgagca
    23581 tggaaaaggg tgttctcctg tagttttcca ttgatcggcg taaacagcat atgactgaaa
    23641 tcacccatcc aaggacttgg ttgatgggta agacggtagc cttgaaaaac gcggtcatca
    23701 ggatgaaacc accagctgcc gttttgatcc gtagtttgcg gtgcaaaata attcatccca
    23761 aaaggaacgc cagtataagg ctggcagttc ccattagaga aatttggctg attcgctgtt
    23821 gcatgtctag tatctatttg accgatattc attttatttc tcctttgttg attgtctttt
    23881 gatgaatgaa actggaaatt tactatcgga tggtcgatct tttgtctcta accaagtgac
    23941 caaagcatct cccgcaagct tacctaactg ttcaaaatct tgtgcgatgg ttgtcagtgg
    24001 cgggtcaaca agagctgctg cttggatatc atcaaatccg ataattgaaa aatcttcagg
    24061 gatatgataa ccatgctgtc tcaagagatt catggtctgg atagcgacaa catcgttttc
    24121 acaaacaaaa gcagttactt catacttagt gatataagaa agcaattcat ctaatgtcgc
    24181 gcttttgtca tccagtgaag tgtggaaagt caaaccagct ttgtccaatg cttcaaggta
    24241 accaaggtaa cgctgtcgaa cggattgtgg atgagtctgc gtaccaaaca aataagcgat
    24301 ttttgaatgt ccctgttcga tcaaataaga ggcagcaagc gcaccgcctt ggaaattatc
    24361 ggaaagaacg gtaggaaaag gtaactcata gattttttta tctaatatga cgacagggaa
    24421 ttctttcaat gaaagctcaa aaagtaagtc aagatgttgt tctgtatcaa gagcataata
    24481 aatcaatccg tcaaattcat tgattagctc ttttgctgtt ttattttgta gaaagtcaag
    24541 cgtcgtcatc atgacatcaa tctgtttatc ttgcatcaca gggttcaatc ccttgctaaa
    24601 atcaccaaca gacaaatcag cgacatatgg aagaagaaac agaatccgtc gtgtttttgt
    24661 aggagaagca agaatctgtt ccggagaagc ggatttaacg aaactgcctt tcccgcgaac
    24721 gcgataaata agtcctaatt gctctaattc agtcaatgca cgtttggaag tgattctgct
    24781 tactttatag gtacgtgaaa gttctttttc agttggtagt tggctgtcta caggtaattc
    24841 accagttaaa atagccgttt gcaaatcatt aaatattgtc tggtacaatg gttgagtcat
    24901 ataaacacct cttaatgata tatcatattc aaataatacc ataatggatg aaaaagtaaa
    24961 taaaaagata ttttttgaaa gcgtagacat aattggctgt atgaagtata atctttaaag
    25021 atatatcaaa tagaaagaag gttttattag tggtttataa agatatacca aaatcggtgc
    25081 agaaatttat ggaagatatc acacaaaaat gtggggatat ccatgcggac tgggcaaaga
    25141 attttacagc agcatttgcc aatactctgt tgacaacagt caaaaagcaa aatgacggaa
    25201 ccaccttttt attgacggga gacattccag cgatgtggtt aagagactct actgcacaag
    25261 ttcgtcctta tttagtgatt gcaaaagaag atgaggaatt agctgacatg atcagcgggt
    25321 tagtcaaaaa gcaatttttt tatatcaata tcgatccata tgcgaatgcc ttcaacgaag
    25381 aagctaacgg tgctggccac caaacagatc atacaaaaat gaacgattgg atctgggaaa
    25441 gaaaatatga aattgattct ttatgctacc caatacagtt ggcctatctt ctttacaaaa
    25501 atacaggaaa aactgatcaa ttcaatcaat cttttattga aggtatcaaa aaaatcttgg
    25561 acgtgttcaa aacagagcaa gatcatgaac actctcctta tacatttgta cgagacacga
    25621 caagaaaaga agatacgctg atcaatgacg ggcgaggtgc aaaaacagct tttacaggaa
    25681 tgacatggtc tggtttccgt cctagcgatg atgcttgccg ttatggatat ctggtaccat
    25741 ccaatatgtt tgcggtggtc gtgttaggtt atgtggaaga aatttttcaa acgatactcg
    25801 atgataaaga aattgtacag caaacacaga aattgaagaa agagatccaa gaggggattc
    25861 agaatcacgg acgaacggtt aatcaaaaag ggcaaacgat ttatgcatat gaagtagatg
    25921 gaatgggaaa cgccacagtc atggatgaca gtaatgtgcc caatctgatc gccgcacctt
    25981 acttgggata ttgttctgaa caagaggaag attatctgca aacaagaaga acattgttga
    26041 gtaaagaaaa tccatatttc tatgaaggaa agtacgcaaa aggaattgga tcctcccata
    26101 cgccagaaaa atacgtttgg ccgattgcat tagctatgga aggaatgaca acgtcagaca
    26161 aatctgaaaa agagcggata ttgaatttac ttgtagcaac tgacgcagga acacacctta
    26221 tgcacgaagg attcgatgtg aacaatcctg aaaattatac gagagaatgg ttttcttggg
    26281 caaatatgat gttttgcgaa ttagtcatgg attactttga tattagagta gaaaagtagg
    26341 aggtatcgta aatgaaaaag aaagtatata tcatttctca tagccactgg gatcgtgaat
    26401 ggtacatggc ttacgaacag catcacatgc gactgattga attgatagac gatctactag
    26461 agctatttga agttgatccg tccttcaaca gttttcattt ggatgggcaa acgattattt
    26521 tagatgacta tcttcaagta aggccagaaa aaagacaggc aatccaacaa gcaatcaatg
    26581 aaggaaaatt gagaattgga ccattttata tcttgcaaga tgattttctt atcagctcgg
    26641 aatcgaacgt gagaaatatg ctgattggca tggaagaaag ccgtaaatgg ggaacccctg
    26701 tcatgttagg ctattttccc gatacatttg gaaatatggg acagacgcct caattaatga
    26761 aacaagctgg tatttcagca gcagcgtttg gccgtggtgt aaaaccaatt ggctttgata
    26821 atcaagtttt ggaagcagaa aactattctt cccaatactc agagatgtgg tggaaaggcc
    26881 ctgatcaaac agcaatcttt ggtctgctat ttgccaattg gtatagcaac gggaatgaga
    26941 ttccagtaga aaaagaagca gctcttgcct tttggaagca aaaattagcg gatgcagaac
    27001 aatatgcctc tacgaaccac ttattgatga tgaatggtgt tgatcatcaa ccggtacaaa
    27061 aagatatatc aaaagcaatc catctcgcaa atgaactgtt tccagattac gagtttattc
    27121 attctaattt tactgactat ctggaagcag ttcaaaaaga tgtgccagaa gacttaggct
    27181 cagtagaagg agaattgaca agtcaagaaa cggatggctg gtatacttta gccaatacag
    27241 catctgctcg ggtttactta aaacaatgga ataccaaggt ccagcgacag ctagaaaata
    27301 ttacagaacc acttgcgacg atggcttatg aagttagtgg aaactatccc catgatcaat
    27361 tagattatgc ttggaagaca ttaatgcaaa atcatcctca cgacagtatt tgcggttgtt
    27421 cagtcgattc tgtccatcgg gaaatgatac ctcgttttga aaaagcagat gaagttggaa
    27481 agtatcttgc acaagattcc ttagaacagc tgaccgcagc aatcgatacg accggattcc
    27541 caaaagacag ctttccattt gtcattgtaa atactgcagg aatggataaa actggtgaag
    27601 cagaaataac catcgaatta gaaagaaaaa gattcgctga aggaatacct gaacaactat
    27661 atcaagagtt agaaaatttg cctaaacgta agtatcatgt agaaacaaaa agtggggcca
    27721 ctataccagc tattttatct gaagaaactg tccaatttgg ttatgatttg ccgaaagacc
    27781 gtttccgtgt gccatatatg gcaagaatga tcaaagtgac tttaccatta gaaaacatgc
    27841 cagcattttc ttgggaaaca ttcgcgcttg tagaagggga agcgaaagca gaagaaaagg
    27901 aaacaatgat tcatcagagt ggacgaatca tcgaaaacgg ccctctacat ttgacgattg
    27961 aaaaaaatgg taccattaca atggaagatc gcaaaaacaa acgaaagttg aataatctgc
    28021 atatttttga agatatcggc gatataggaa atgagtatat ctttaaacaa cctttctgtg
    28081 atcagccaat cctatccagt aacaaagaaa actctgaagt aaaagtatta gtagatacac
    28141 cggaaatagc aaaaataagt attctacagg aaatggaaat ccctgtttct gcagacgagc
    28201 gtttagaaaa agaacagcag atggttgtgg aatttcgtta tcgaaaagca gaacgatcca
    28261 aagaaaaacg aatccttcaa ataaaaacaa tcatgacaat cagaaaagat agtaaaaaaa
    28321 tcgactttga aacgactctc gacaatcaga tgaaagatca tcgcttacgt gtcttgtttc
    28381 ctacaaagtt acatgtggaa catcacgaag cagatagtat ttttgaagtg gtgaagcgcc
    28441 caaaccatgt gtctaaaagt tgggaaaacc ccacgaatcc gcaacatcag caagcatttg
    28501 tcaatattca tgatgaagag tacggtgtaa cagtcggaaa ctttggtttg aatgaatatg
    28561 aagtaacaga agacggacaa atcgcagtga cgctacttcg cagtgtggga gaactaggcg
    28621 attggggata ttttccaaca ccagaagcac agtgtctagg tgagcatcgg ttcaattaca
    28681 gcattgaact acatggacca gaagaaaaat tctctactta tttgcatgca tacgcagcac
    28741 agattccttt ttccactcaa caaatcaaac atcatgaagg aacattgatt tcaaaacaac
    28801 aatatttaac gataaaaagt gaaacgtttg caattacagc tttgaaacgc agcaagttta
    28861 gtgataaagt agtagtaaga ggtttcaata tgtctagtca tttagaaaaa ttggaaataa
    28921 ctaaagacaa tggaaaaact gtcatattga atctgcttga agaaccaacg aagcaagcgg
    28981 ttgtcccaat aatccaacct tatgagattc ggacaatcgg attcgaggag gaaaacgaat
    29041 gtatggcgga atagaagcag gcggaacaaa atttgtgtgt gcggtttcag atggtggaga
    29101 aattttagaa aaattaagta tccctaccac aacaccagaa gaaacattgg atcaggtatt
    29161 tgaatttttt gatcgttatg aattgaaggg aatcgggatt ggctcattcg gcccgattgg
    29221 tatcgacaaa acaaaagata attacggata cgttttggca actcccaaaa aagggtgggc
    29281 acaattcgat tttcttggca caatcaagga acgctacaat attcctgctg cttggacaac
    29341 ggatgtcaat gctgctgcat atggggaatt gaagcaagga gcagcacaag gaaaaaatag
    29401 ttgtatttac cttaccgtgg gaacaggaat cggtgcaggt gtcgtgatca atgaagaaat
    29461 tttttcaggg atcgcacatc ctgaaatggg acatatttgg gtgaaacgcc atccagatga
    29521 ccattatgaa ggtacttgtc cttatcataa agattgttta gaaggattag cagcaggacc
    29581 gtctattgag gcacgcacag ggatcaaagg gcaagatctg ccgcaagatc atcctgtttg
    29641 ggctattcag gcttattata ttgctcaagc actgatcaac tatacgttga cgttagcacc
    29701 tgaaaagatt attttaggcg gtggggtaat gaatcaggat catctccttc aaaaaatccg
    29761 tcagcaattt gttgaattga tgggtggtta tatggaaaca cctcaagtaa gtgaatatat
    29821 cgttcgttgg ggactgccga atgaaagtgg gattatcggt agtttgctgt tagcagaaca
    29881 cgaacatcaa aagtaagcag acaaattaca caaaaagaac agagtcttat cattatctgc
    29941 tgataagact ctgttctttt ttatttctat tcccataatc caggtaaagc tttaccgact
    30001 attttttctt gagtaaatgg atggatcatg tgcagttcta atgcatggag catcagtcgt
    30061 tcagctgttc tattttggta gagagggtct ccaacgatcg gatgtccctt atgagctaaa
    30121 tgaactctga tctggtgtgt acgtccggtt tccaaaacac aatagacttg tgtttgttca
    30181 gaaagtactt tgttgacagt gacatgtgtc aaggcgctct gaccattttt atcatctacg
    30241 accctttttc tccgatcatg gcgatctcgt ccaattttat tggtgatggt catatctttg
    30301 gcaatttctc cccatacgat ggcttgatat ctccgataga tcattttttg ttccaacatt
    30361 cttccaagta tcggcaagac aaatggattt tttgcaaata aaacggcacc gcttgtttct
    30421 ttgtccaagc ggtggacaac gtaaggtcgt tgctgtttag tgtcgagata agcagctaaa
    30481 tgattgagta aggtactgtt ttctgtcggt tcatttggat gagtcttcat tcctgcaggc
    30541 ttatccacta taatcaaatg ctcatcttca tataaaacac ggatgtgctt cgcatctcct
    30601 aattgaactt cttgataatt ataatctgtt tcttcgaata acaatgtgat ctggtcattg
    30661 ccctttactt catgatggaa caaagcaggt tgttgattga tccaaacgtt tttacgtata
    30721 cgcaaaaagt gtcgaacctt tctaggaact aaccattcct tttcaagcaa gtcgcgaatt
    30781 gttgtttcag gatggttcat aggtaaagtg atcgtgattt tcacaagtgt actcctttca
    30841 gtgcaattgc agactaattg taccattttt aaaacatatt taagaaaaaa cttacatttt
    30901 tctgttcatt cttatgttac tctacttgca ctaacgtaaa aaaacatatt gaactacaac
    30961 ttaagcagga agaaaacact ctttcactat ggtaaaataa gacgattgaa tcaaatagac
    31021 aggagaagaa gcaaatggat tttcaaagca ttttagaaaa gataaaagct gctttgatca
    31081 gtttttggcg ttggatcaga ccatatctcg gacaattcca tcgatggcga aagcgcatct
    31141 ggaaaaaata tcatgtgaac aaattgattt tgctgattgg tttgatctgt gtcttagtga
    31201 caagtatcta cctctttatt ttagcaaaac aagcaaatgt cgaaacgtta aaatcaggat
    31261 taagccaatc gacagtcatt tatgataaga aaaacgaaga agctggcaca ctgtacgccc
    31321 aaaaaggaac atatgtagaa ttaaacgcga tttctcccta tatccaagat gcagtaatct
    31381 cgacagaaga taggaatttt tacgagcatc acgggtttga tatcaaaggg attgcccgtg
    31441 cagcagtccg aatggtcttg tctggcggaa catcaggggg cggaggaagt acgatcactc
    31501 agcagcttgc caaaaatgcg tatctgacat tagaccaaac gtttgatcga aaagcgaagg
    31561 aattattttt ggcaatcgag atcgaaaaga agtacagcaa agaagaaatc ttgaccatgt
    31621 atcttaacaa tgcctatttt ggcaacgggg tatggggtgt ccaagacgct tccagaaagt
    31681 attttggagt agatgcaacg aatgttacgc tgtctgaggc tgctactttg gcaggaatgc
    31741 tgaaaggtcc tggtatttat aatccgatcg atcacccaaa aaatgcgaat gatcggaaaa
    31801 acacagtact aagtgtaatg gaagaaaacg gaaaaatcac aaaagaacaa gaacaagcag
    31861 aaagccagac agatatcagc gcgtatctta atgacacata cgataattca gattctggtt
    31921 atcgttatcc ttattatttt gatgcagtga tcgatgaagc agttaacgag tatggtcttg
    31981 atgaagaaga tgtcatgaat aaaggctata aaatctatac agctttagat caggattatc
    32041 aaaagcaatt agaagctact tatcaaaaca gtgcattatt cccagcaaat gcttcagatg
    32101 gtgccatggt ccaatctgct tcagtagctt tagatccgaa tacaggtggt gtacaagcac
    32161 tagtaggacg aagaggagat catgtcttta gaggattcag ctttgctaca cagatgcgtc
    32221 gttcaccagg atcaacgatc aaaccattaa gcgtatatac accagcactg gaagctggat
    32281 acaagccttc cagtatcttg aaagacgaac cgcaaagtta ttacgatgcg cataattttg
    32341 acgggacata ccaaggagaa gtaccgatgt atcaagctgt tgcacaaagt ttgaatttgc
    32401 ctgctgtatg gcttttgcat gagatcggtt tacaaaaagg atatgataaa gcagaagaat
    32461 tcggcctgcc tttagcaaaa tctgataagt attatggctt agcccttggt ggactggaaa
    32521 aaggagtatc tccattgatc atggcgggtg cttacagtgc atttgccaat gatggtcaga
    32581 tgtatacgcc gcatcttatc acgaaaatcg ttgattcgac tggagcggtg atcgtcgata
    32641 acacaaacaa aaaaccaaaa caggtcatat caaaggaaac agccgatgaa atgaccagca
    32701 tgcttcttgg tacattttca aatggaacag cggctgctgc gaatcctgca ggttatacga
    32761 tagcagggaa aacaggaacc acagaaacta atttcgatgc cacaaaagca aatgaccaat
    32821 ggatgatcgg ttacacgcca gacgtagtga tttcgacatg gatgggttac gaagaatcca
    32881 gcaagctgca ctatttggaa gggacaagtg gaaatgttgt cgggaaagtc ttcaaatcag
    32941 cggcagaagg catccttccg tatacttcaa aaacaggatt tagtgtagca gatgcctatg
    33001 ccacaggagg acaagtggta gctgcagatc aagttggaaa cacaggaaat tctaatggag
    33061 agtctggaaa ttggcaagat aacttgaatc aatatggtga acaagcaaaa gaagggctga
    33121 aaaacttcgg cgatatggtg aaagaaggcg ttcagggaat tggtgaagcg gctaaagacc
    33181 tctggcggaa atatcaagga gagtagcccc tttgaaaacg aataacccca tgttacaata
    33241 gagagtaact actaaaagaa aagagggcat aacatgtcaa acatctacga tagcgcgaat
    33301 caaatcgaac gtgagatccg tgaattacca gaattcaaag cgttgaaaga agcgtacgag
    33361 aaagtacaag caaacgaaga agcacacaaa ctgttcaaag acttccaagc gatgcaaatc
    33421 gaattacaag aaaaacaaat gagtggacaa gagttcagcg acgaagatgc aatgaaagca
    33481 caagaaatgg ctgtgaaaat ccaatcagaa gaagtaatca atgacttgat gcaaaaagag
    33541 caaggcttca gtacaatcat caatgacttg aaccgtatca tcatgacacc agttcgcgac
    33601 ctttacagcg aataaaacta ttttatgaaa caacagaggg tgtgaaagag acgttcggcc
    33661 ttgagcgatg acaaaattgc ttcttattgc cgataggctg tctcttgaac accatttacc
    33721 aagaggtcgt gagcctaccg tttaactctg agttacaagg aacaatttca aaaaacagct
    33781 tctcatgttt gatgactatt gtgacttgtg accgaggagt tggcaggaga acaccgttta
    33841 ttcagaaata ggagctacga caaaagtctt gtcatagctc ctattttttg tcattcattt
    33901 ttcaagcggt agaaatagcc tttttgagct aacagttttt cgtaagtacc tatttcaacg
    33961 atttttcctt catcgatcac aacgatttta tctgcctctt tgatcgttga aagccgatga
    34021 gccacaataa aagtagtggg tgtttctgtc aggtaattca gggcttgctg gatttttttc
    34081 tctgactggt tatctaaagc tgaggttgct tcatctagca aaatgatttt tggctgacgt
    34141 atcaacgctc gtgcaatgga gatacattgc ttttggccac cagacagctt gttgccatgt
    34201 tcgcctacta aggtatccag accatcagga agctggtcaa tcagtgaaga aagttgcgca
    34261 gcttcgatga cttcatctaa acgttctttt gatacgtttt tcaagccata agtgatgttc
    34321 tctttgatcg aagcggagaa caacaaagtg gtttgaggaa caacggctaa ataatttcgc
    34381 acacttcgca tatccagttc atccaaaggc tgatcatcta gaaaaatttt tcctgaagtc
    34441 ggctggataa atccaatcaa taagttaagg agtgtagatt ttccagagcc agatggccca
    34501 acaaaagcaa ttgtttctcc agctttcacc tctagagaaa aatgatcgat aatcggtttg
    34561 agtgagtccg gataaagaaa agaaacatcc tcaaaacgaa aatttccatc caaatgttgg
    34621 atttttttct taccgtgata agtttctaca tcgccagcaa tcaacagttc gccaatagaa
    34681 gtgatagatt ccatgccttt tgaaatcgta ggaatcagcg tgatcattcc agaaacggaa
    34741 ttgacgatcg tcgtgaaata cgtctgatac atcacgacat cgccgggttg gatgcgccct
    34801 tgtaaagcta atatcccagt gaaactcaaa caaatcagct gaaatatctg aaaactagcc
    34861 cagctgactg atccgaaaac agattgcagg atatctaagt ggaatccttt ttcatagatt
    34921 tgagtaaaat gcttatttaa gcgagttgtt tcgtgttttt ctaacccatg agctcgagca
    34981 atcggtgcta attcgatcac ttcgatcact tttgcagaag tctcttccat ttcttgcctg
    35041 aagtctgagt tggactgtct gatcctttta cggaaaaaga gagtaacgaa tgcggcgaga
    35101 ggaacagtca ataagaaaaa catgaaaaca acaggacttt tataaagcgt gatacctaaa
    35161 gctacgaata aattgacagc gatatttaat ccgctgacaa atacttgaga ggacaacgtt
    35221 tggatagctt ctacatcacg gatgatcttt gactggattc gtccagattg caattctttt
    35281 tgataaggaa tagatagttc ttggattttc ttgataaggg tcgctcttag tccagcttct
    35341 acttgacgga tcgaagtgct atggtatttt acatgaaaat aattcgtcaa tatattttga
    35401 ccaatcagac aagccatcaa aaaagcgttg aaataaatgg cctgcaactg agaagaatct
    35461 ttcgatgaag ctgcattgat tacattggca atagcgatcg gcattaacca agatggaaga
    35521 tgtttgataa taaaaaagag tcctgacatg gcaaaacgcc aataatttcc ctgataaaga
    35581 tgcagcaatg tctgaaaagc atttgcatga tatttttgat aacttttctg tattcgttcc
    35641 tccataatct tctccttaac aatcttggta aataaactgc aagtgttcta ttgcttcagg
    35701 aacataaatc tcaggagtag cttcaagagt ggcgtacatt agaggacgct catatttgat
    35761 ataatgcagt accgggcgga aatctaaaca gcccttgcca acaggtacca tgcggatctt
    35821 tccattttcc atgatatagt ctttgagatg aagcgctgta atataaccat gtaaattgtc
    35881 caaggcacct cggatcactt tttcctgatc agcatgattt tctttatgca tcaaattcgc
    35941 acaatctaaa atgattttta aatttggtga agctacttca tcgattaaac gtttagctaa
    36001 ctgatagtta tagattggat gattgatccc tgcttcaaca gcaacagtta cgccaaaatt
    36061 ttctgcatga gcgactaatt caatgataga atttctggcg atctgataag cttcttcagt
    36121 aaaattttct tttgtgtaac cgacagagac actaccggtt tccgtagcaa tcatcttggc
    36181 ttgataggca gagcacagag caatttgctg tttgaaagtt gccaatgctt gtgcacgaac
    36241 ttcttgattt ttgctggata ggttgatata gcatcctaaa atggaaagtt cgatattgtt
    36301 tttttggaag tattcaccaa aataggcagc actcccaagt gtcatgtcag ttaatttaag
    36361 ttgttcagga aatgcttttt gtggtgcaaa ttggatatgg gacaagtgaa gctgtgatac
    36421 tttttgaacg atttcttcac gatttcgaac atctaaatcg tgggcacgga tgcctaaatt
    36481 taatggaaac atctcaaact cctttttgta aataattagc aagaggcaga cgggattctt
    36541 ttatcaattc aacaattatt cgggcaactt tatcagcgcc ttctggacta aagtgggtat
    36601 tgtcttttag tccttctggg taatttttac aagtatcagg cataagatgc aggtagaatt
    36661 tttttgtctc ttcttttgag aaggtctgga acaattcttg tgatcttgag aacacatcta
    36721 aaagaggaat atggtgtttc tcagcaaatg cacgcatcgc ttttggatag tctccaagta
    36781 tatctggatt caatgttccg ttttctaagt aatctcgtcg cgtcacagat gtcagtaaga
    36841 ccatttggac gttcgctttt tttgcgcatt caaaaaatat ctgcagattt tttaaatagc
    36901 taccgaaggg aagcgtacct ctttcttctt ggattttctg gtcgttatgt ccaaattgta
    36961 caaataagaa atcattcggc tgaaactgtg aagctagacg ggctaacctt ccttcctgga
    37021 taaatgattt ggtgctgcgt ccattctttg cttggttatt gatctggatc tcgggtgaaa
    37081 aataagcaga gattttttct ccccaacctg tctcgggacg cttgttttca tctttttctg
    37141 ccgcagtaga atcaccggca atatggatag taggcatgtt atctcttctt tcataaaggt
    37201 ttataggcaa tgaagcagaa cagcaagaga agaagacgga gcaa
//
LOCUS       DADGKS010000020        36192 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.020, whole genome shotgun sequence.
ACCESSION   DADGKS010000020 DADGKS010000000
VERSION     DADGKS010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36192
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.020"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            44..379
                     /locus_tag="JXV47_001134"
     CDS             44..379
                     /locus_tag="JXV47_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487191.1"
                     /translation="MKQYLNEWKAIEGSLVTQRIKELPDCLEKDHLFQIREMLKKEQF
                     DPDQFLVVEYPTIGVYCCNHINDGKYFIIQEYGGQLTPFYTTWEMSEEGINNFPCESI
                     EDSISHTEC"
     gene            complement(636..2219)
                     /locus_tag="JXV47_001135"
     CDS             complement(636..2219)
                     /locus_tag="JXV47_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487192.1"
                     /translation="MFILDDEIKKVKNPRIIPLLEEVRSSFYQGNYRSAIAVNYSALI
                     LDLIDKLSDLANIYEDNTSKKILEDIARLRKSDPNSPKWEMELLEKAYSSTELIDSYE
                     YEDLKYIKDQRNYSAHPVVTYNGNTWELRDITKETCQDVIRKSYEIIFLKNPILGKKV
                     TIEIIQYASRIHAMSVTPEEFHSALKNSYLNKLSEKAKENLCKTAFKFVFQLSYGNEE
                     ADRDRESTFRLLNALIFDNKEFYLNILKKEIAKYRFTAESREEINKSLGENQQITYTK
                     GFFLLTFIATHPELQHDFSDETIQNLQISINDFKPKQQVLTEIEYYYRLRSLAVLGNN
                     NEELQNHLNSLVDPILQQKMRVSSLPSSTLETIYNQYLYFGEKEMFIDFMIEHLTDAS
                     SFRLADKDMEVLPWIYNKLNQEQFNKLLYNLNGNNQFYKNSNFPPFISNLLDFYNQKF
                     QVNLRKHYSGLLYPNAVTMDQGFQLKDKELKKLYELAESKSDMYLDIIDNIINKSEDY
                     LRKEINSEKELLNYVHKIK"
     gene            2341..2925
                     /locus_tag="JXV47_001136"
     CDS             2341..2925
                     /locus_tag="JXV47_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487193.1"
                     /translation="MDLKQSFYIWLYPDNPMSIMADIFVVSILLYLFYLIFFHNLIGY
                     MILDWKGMFDIERKPFANNQTYTVFESGDWEENEVDVIHEIGLALSGIQDADVLVSMT
                     TDTGYNAYEVFYLMYFIWRDGQEIINGRAEKTINSNTEISFCMGEGEMIVYKDGSANI
                     KTAFGDIETSIKELREYVQNPYNFQYLAGRINLV"
     gene            2936..3181
                     /locus_tag="JXV47_001137"
     CDS             2936..3181
                     /locus_tag="JXV47_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487194.1"
                     /translation="MKKIINQPTNHLIIEGVIFVTMYFTVGNGISNTIIQKNPQYLLF
                     SLYAWIVQMVWVSILMLLFYWIVRVILLLLNKRKKDR"
     gene            3187..3909
                     /locus_tag="JXV47_001138"
     CDS             3187..3909
                     /locus_tag="JXV47_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487195.1"
                     /translation="MKSTKLKVVLLSTAALITLTACGTTNSANNNKDTKSSSTMVTKN
                     STTSASTTMSSMTENNAEKYQKYEDINKGQKPDEVYNNFINTVKNDENYGNDPLQNKN
                     LTIVLYKPDCPDCQKAESKIMQEIKEGFSYAPTLMHDITINKPAYEYYAVAVDITDGV
                     PEWVQNIPGLADENNQYHTPTVAVVTPKKVNGTLYWDVMGMTTNTTDEMIESTTKYYM
                     DLGAYKLYQQSEPVMDDQSKVK"
     gene            4040..4783
                     /locus_tag="JXV47_001139"
     CDS             4040..4783
                     /locus_tag="JXV47_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487196.1"
                     /translation="MKEISANEAHIPQKNQVGIYKVLHGEGIYKIQLLTGYNNGANGK
                     WLKATSIRELRSEVEKIRLGLTSEEIAKLKGNNSFVIEKEKEKHLLYRELKIEEYYEI
                     DLPEKLRIIDQRSEEKWKTEIYPSLNDYKTSGKPMYNYTGFLTYTQYKYAFRKLKGIK
                     QAEIALYEMKKVDRLKLIQDLVQNTWNQAIVELEKENGKILTNKYLIVNEIEELIGLF
                     SCEKGEVFLKSSPTYSILDSPYQFIQARR"
     gene            4789..5154
                     /locus_tag="JXV47_001140"
     CDS             4789..5154
                     /locus_tag="JXV47_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487197.1"
                     /translation="MSSLKDDYIQAKQEYEKIQMLKSEKVELFLTQKLAEDHIANLDA
                     KTLEEYDRQFNQIHHNIILLVEQAKRRFEKAEYDLLDQGIVCLDKGLRRYYGAELKKQ
                     NVDRNALKHEILELIMQRI"
     gene            5170..5700
                     /locus_tag="JXV47_001141"
     CDS             5170..5700
                     /locus_tag="JXV47_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487198.1"
                     /translation="MSQNISAVKQLIEEDLETTVQRLAERIHFANYQTISNWSSRNRN
                     PEEIPMKFFYRIGKEYGVDPIKIFEKTMIYYYHGTPNEVLEHLLEEAKEKSSILELSQ
                     NDKVIQVKCVDPTGKIIVGFDIERKSKIDFITQLKKINNLDILTLRPDHEQLFMSFKK
                     QLKEIQKRYNKVFPNA"
     gene            5862..6170
                     /locus_tag="JXV47_001142"
     CDS             5862..6170
                     /locus_tag="JXV47_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487199.1"
                     /translation="MWNNRLKTGLLLIVISCAMMIGMRIQREQSYFEVSANNVIEKCY
                     YGQHYWSEEVRENIDREYVQRIVWDAYSIKDYPKSLTSRLFYSEKDNQKLSDLMMKKV
                     "
     gene            6166..6585
                     /locus_tag="JXV47_001143"
                     /pseudo
     CDS             6166..6585
                     /locus_tag="JXV47_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352869.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            6722..7522
                     /locus_tag="JXV47_001144"
     CDS             6722..7522
                     /locus_tag="JXV47_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487200.1"
                     /translation="MSEDLRELKLRKKQYDQYFSGLLNKHIEEGLDHDFGKDEYCLYC
                     ERYNEKMSEYLQLKKEIQKLEKKVHAWKYKDSMSGYVESQNKPRKKKQAYVLKMVNGE
                     ELIVLAYSEEEVRELVETPVRKKVETINEIDDSQYNSIYIETSHGGYKKLATFLRSSK
                     VGIISKKDISAVTDSFCTLSVPKAYFQYDSKRFERLEKFCRPYTVLKTKKFNKTKRVS
                     IQLPTGQISLGEKDYLIKVGKELIIKVPEHLFKENFEIRETLVWKEEK"
     gene            7559..7741
                     /locus_tag="JXV47_001145"
     CDS             7559..7741
                     /locus_tag="JXV47_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487201.1"
                     /translation="MAVNKILQVLIIDEFGGGEWFDVQSIDFEEEVVVIENIYGEVYS
                     YSLEGENIEDLRLIGE"
     gene            7852..8169
                     /locus_tag="JXV47_001146"
     CDS             7852..8169
                     /locus_tag="JXV47_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487202.1"
                     /translation="MKREEYKQRLNELLEEDETLTHGSPDEILYMIDNMVIFGGYELG
                     NRSVDHNILEFDDVSWEEILDWGILAVPETKTYISDTMVPFFEELDYKRLPKNENHIL
                     GGN"
     gene            8172..8404
                     /locus_tag="JXV47_001147"
                     /pseudo
     CDS             8172..8404
                     /locus_tag="JXV47_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321015.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8519..8998)
                     /locus_tag="JXV47_001148"
     CDS             complement(8519..8998)
                     /locus_tag="JXV47_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487203.1"
                     /translation="MTDKTSDLPKLAPKTSRVKSKKDGKTKNAVKKKSVKETSSLLLD
                     IPMSSFDDNTDETSVKIATHVGMNNQNDSFYNLLNSLRELEDKKNQVIASKAPDLTTD
                     LDAEIIQIKQDERSVKSLLKTYFDGFDKELAPYSQAILTKPIQAPHISISLQKKSDD"
     gene            9118..10455
                     /locus_tag="JXV47_001149"
     CDS             9118..10455
                     /locus_tag="JXV47_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAX1487204.1"
                     /translation="MLMVQFTGIAMSVITINPQVIHADGIATYDAQFNCTTEGSGSGT
                     DSDGNDTGSGAVTGDVAKNIEDIYKYMNGEYGLSGASIAGILGNWKQESGIDPRAVEG
                     YYGDGQREVDFIKQFTDGLMGIGYGQWTAGRHTALVDWSKKNNGGSWWTTEAQLDFMF
                     KGDGGFVGILKDYALNASDDVVENAVTFHKNWEISADSESAVIAVRGENAKEIWKYMK
                     SKGMDGAKDESKINKISGGSSTGDGSNNSSSSASGTVEDACATTDDANSGSGSIGKEG
                     KINGKKGQVIANMTYEEALKKYGKAITLPKFKEPDWSTSPFNGIYQGQCTELTWAYMS
                     QLYDGNQPTTGNGGYVWESYKSAGAKITNKPIVGYGFSASDGWLWAVGDAGHTGVVIA
                     VFEDGSFLCANFNVPPTQAPTRGVSVTLIDGVDGSDNVHFFSGVGKAKFEIEK"
     gene            10478..11005
                     /locus_tag="JXV47_001150"
     CDS             10478..11005
                     /locus_tag="JXV47_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487205.1"
                     /translation="MNSKVKDTIIISLLSGMLLALLVGILFFNKQNQDIEAEKHSVHI
                     EDKLTFFKEVKPNEVDGLRKDLENDIQEMLNGSVQNKFADQSGEEFLRKLFIVTGKPP
                     ITDKSSEKEKIEYYKPFTFKLTNFGIKTSSSGLYEALTDFEVQYNGKKVYDTTLTITL
                     NNDKKVTGGAFYAKS"
     gene            10992..11555
                     /locus_tag="JXV47_001151"
     CDS             10992..11555
                     /locus_tag="JXV47_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487206.1"
                     /translation="MQNHEITTAKKAIGILSIIVILCCVVLFQKKNAYDNNVKELEDL
                     KSKQIEVVKNNQKVKAMQEAQYKELGNAEIKEQSRKFFNLFYNWNSWEKYTKNMKEIQ
                     KEFPQIVKSSPVDISGTMVGTGNSPISSYTADYYTTNQKGKMVELITQTRNTPTTATT
                     TIWRGVTSIGENQLFYLEDLDSYVRAE"
     gene            11977..12714
                     /locus_tag="JXV47_001152"
     CDS             11977..12714
                     /locus_tag="JXV47_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487207.1"
                     /translation="MADHKLEKLLEETWNPKEFSEFFMENFETDLAVIVKDALREQGY
                     PETANYININFTLYTENKGTWDFWATLANKELSDKSDTGIRNFFESNRDDYMYANNQN
                     KLNFRVEFDETPEEFIERQPPKENVAKVLEDRWNSDEIVSTISELGGQYEPLVEAVRE
                     ELRLNKFPDVQNIDVSQIEINVKITNKLDYGSWADIALEKYIYSTLKEFIENRMDIMY
                     LQHPQYLNFGVEIATPLEEWKMEQGLD"
     gene            complement(12731..13147)
                     /locus_tag="JXV47_001153"
     CDS             complement(12731..13147)
                     /locus_tag="JXV47_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487208.1"
                     /translation="MNKKRKLSVLITLVSILTILSVILSLKIFNQINTSSNAKDGIVV
                     ENTSNSKETGTTTKKDKSAEITTKNYLIKTVYFDERKTAILKDEEGSELKLPITVSDK
                     FNGTFSLQTAEGSPDNLKVGQTIILGKNDELYSFVK"
     gene            13540..14787
                     /locus_tag="JXV47_001154"
     CDS             13540..14787
                     /locus_tag="JXV47_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487209.1"
                     /translation="MNMKRNSLGMVLLASAVLAGLSVPVTSHADEWTANTPDQIQITT
                     GQSSYAFKKGDTIWSTVEKLKSLGYKTTVAEFAELNNVDLAKGEQRTIPIGRTFNISK
                     DTLTVKEADGEVVSQTVQKDKPDPIENTEQENKKSETTKESEPTANTSDKTETSASSV
                     DGASSSNTNNSTSEKEASQGTSESSTTEADTGTSTNNSQSTSNDANESTSTSSSDQSQ
                     TGSSDETDSSTSPSKPEQPTNVVLGVPFISQGNTMLCEGTSLLEALHYKGVATNQDLM
                     TFVKSMPLSPDNNPNNGFSGEWRHNVDGTYQGMNPAPVVSWGVANGGNVVDISGSSVQ
                     GLKDEIVNGNPVVAWVTYAFEPAQHKPMFWGDAIWNRHVVAVDGFKDGFYHVVDPVFG
                     ASWINAGSFETAYNVSQLAVSVR"
     gene            15055..17445
                     /locus_tag="JXV47_001155"
     CDS             15055..17445
                     /locus_tag="JXV47_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HAX1487210.1"
                     /translation="MKHEKTIILKSKIIYCFATLVMMLSTLIMPFSAIRAEADVTKPT
                     SAKFIETGVKTDGYIRVNMPNHPNEWMISSQFKDSHGNIGYCMDSELPSPTGSGAGSL
                     KYKGAGSDEFYRMFKGGFPSKTAKELGAGNDTEAWYATQLVSWVLAGNFKVSQIVWSH
                     PNHTAAETARVKKAFEKIYDYAKNGKDTPNTEFSITASKTADEGKYHTFTYKTASNKT
                     GNAKLTFTSAKPAGMKIYDADGKEITNNTVKLNSSFTIKVPVTTPSGTLSFKGTANVS
                     TTNPFTFDGRGVYQDAVVMITTSETKDSKSLSAKWTRAVGQVTVKKVDQDGNALKGAE
                     FTLTDNNNAKSVKTTGDDGLATFDLQQGLTYSLEETKVPEGYQGSFKKDGITVNTDGQ
                     EFSYTATNTIKKGKVKVKKVDQDGKPLANAEFTLTDDSSQTQAEKTDENGLASFDIVA
                     NKTYSLEETGVPTGYTGVFKQEGITVKDDGQTFEYTATNTLKKGLVKVHKVDQDGKPL
                     ANAEFTLTDEKGATQVEKTDENGLASFNIVANKTYSLEETGVPVGYTGAFKQEGITVK
                     DDGQTFEYTATNNLKKGVVKVHKVDQDGKPLADAEFTLTDEKGVKEVKKTDATGLATF
                     NIIANKTYNLEETKVPTGYTGAFKQEGITVKDDGQVFEYTAKNTLKKGVIKVHKVDDQ
                     GKALANAEFTLTDDKGVKVVQKTDSNGLATFNIVANKTYKIEETQNPNGYTGKWSKEG
                     ITVADDGQTFEYTVINHLVPETVRTGGIGTSAFLLVFLIAGLSMVLLYYREQHKAK"
     gene            17494..19329
                     /locus_tag="JXV47_001156"
     CDS             17494..19329
                     /locus_tag="JXV47_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAX1487211.1"
                     /translation="MKSKKIFSNLMLFGTLLGVGLGASSISSSLGLGGQVAYAQQNYN
                     YQGTGTIHIHKVTNTNGDGNPVSDIDNKGKEIALPNGVKPLEGVEFSYVKLTKDEAKS
                     LGWTDSDTTKGQHIDDAKARLLLNKKYSEVSRMKTDSQGNIDIPIQVNTDDLTDNLYL
                     IVETGTVKGVVEEAYPMIVNVPELNGSDDQYFNYDVHVYPKNYFQLNSAELDKKDEDG
                     KALAGTVFELRKDDGSDQVVGTYKTDSTGKLTVDGLELGDYYFLETDLGTDANKTTYL
                     LDGKKFKFSVKRGETAKVVLDVTNYKRPVITKVIDKETVDTGEDVQYTLKPSIPGNIG
                     NYEKYVVKDVLGAELTYDSSEVIEGMTLDTDYSIERDGQTTNYVFTESGMDKLQKQFD
                     AGDRFFTILMNAHTNSKAKMDTPLKNDVSTIYNNGYEPEDETPVDHAYTIIGDHQFIK
                     TDGDTSKALSGAKFVVKNKIDPNKVTYLKQDPTTKSVTWIADKSKATEFVSGSDGKFQ
                     IEGLQYTYDVDFDKQGNPTITDKKINDYALEEVVAPSGYTPTRNDVPFVVSNDDASSE
                     VTDIKNLKTPETVRTGGIGTVVFLVVAGVAGTGLYVVYKREQHKA"
     gene            19404..20261
                     /locus_tag="JXV47_001157"
     CDS             19404..20261
                     /locus_tag="JXV47_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAX1487212.1"
                     /translation="MKKKNIKLIILKIGMLLCLGVGLYPVITQAYTYYQTQQTLNSYK
                     EKYDEASEKENEEVFKRYSEVNRKRKDTEQTSVTIPEDNNNIPSNGNLQKDKLGELVG
                     EILIPKINVDLPIYDGVNDFQLSAGAGILTGTDYPTGGIGNHSVISAHSGIPNKKYFT
                     DLELLKLGDKFFIDISGKKLAYQVDRIKTILPTEFEDLLPVAGKDYVTLMTCTPVGDN
                     SHRLLVRGVSIPYQKSIVEKEKKKEDLKVKAQMNWYPIVVVGVLLIIAVIVIIKKIVA
                     KRRGMKNEE"
     gene            20251..21360
                     /locus_tag="JXV47_001158"
     CDS             20251..21360
                     /locus_tag="JXV47_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAX1487213.1"
                     /translation="MKNKILLFLTLICTLVLTIYPANQLYHQFKTKENVAEIQEKIEK
                     KQTPSKEEVAKKVEQIKSNSGNQGLDNTQKTDKGVDNTQETDGGSFDIREAEGKVNPY
                     TGDVFSKNQTKDFEPSTYSGAVGYVYIPKINVLELLFLGASQEHLYRGVAQMSATSLP
                     LSGKGHQTVIAGHRGGYTSPQFLYVDQLVAGDHIYIDYLGEKAVYTVFRTDVIRNYGQ
                     NSTLTDIPDLDMLTLYTCHPYPQNYDRLLVRSLRDEKAKYITPQVTVGNTAYADAIDS
                     ESVSDKTETVTSSNDLFEDVDRANKELDGNNDLNIPEQGSVEMQDRTFAEKASSIFTG
                     ITNKHQKMLLVIWTVIGALASLKVLILLIKEFRKA"
     gene            21699..22499
                     /locus_tag="JXV47_001159"
     CDS             21699..22499
                     /locus_tag="JXV47_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487214.1"
                     /translation="MVGVSKTALDSLAKLFSSRFDGAEFVEYLSQNESGKTLIETMKK
                     DYLNENDFPTWTNIEDATWDVVCTIYSPWVTIADFVLDKIGGDTYPDAKSLATSDFKT
                     FYGYLIGLIGNGIDLKVTPKQTPEEIEKEKGEVQMAYANDREKVKLLEGKLSEEELGK
                     MVQEINEDSNYFPELKVYQNDEDFFNEMFSNSPWEAVSKTNLGEWNFQDDLVAFSNDG
                     YLRSYSESEYRAELKTYETDILMSYLNLLESGQGELRDKVEELLKEEL"
     gene            22587..23393
                     /locus_tag="JXV47_001160"
     CDS             22587..23393
                     /locus_tag="JXV47_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487215.1"
                     /translation="MRGDQTMSATTDMALEAVIKDNTGNVENVEDFSDIAINLSAWIS
                     AVGEENIEFEIKNMDDLKAKFPFIASKLSQVAEDKSWNELVSFSEKIYDITQEDECVS
                     WEMNNQYKKIDAFVKSRIEGTAFEFEGIDTADNWLNKESFIKSIADDLEKQWSKEDYA
                     EYLKTERDTEVKEKLTEVCLDEHIDPNIVKQEDYEVVIDKVPTDFEEVVKYIVEEALS
                     QYSSDEEVDEETVRTRVWQLVFDDKDYKYLSDQNSVNWSVRLLIDQNDIE"
     gene            complement(23410..24837)
                     /locus_tag="JXV47_001161"
     CDS             complement(23410..24837)
                     /locus_tag="JXV47_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
                     /protein_id="HAX1487216.1"
                     /translation="MMRKQSIEGRNQFAMLTIDDLVPKDHLVRKIDAAIQFDFIYPIV
                     ESTYSTYGRPSIDPVVLIKLVFIQYLFGIRSMRQTIKDVETNVAYRWFLGYSFEDPIP
                     HFSTFGKNYVRRFRETTLFEDIFSHILEQAVKAGFVTEDNLYIDSTHIKANANKHKFT
                     KEMTYGQAKAYQDELEDEINKERIAVGKRPFTWDTESELSLQKISHSDPESGYYVKGE
                     REKQFAYSAHTSCEDNGFILSTLITPGNVHDSQVAIDLVKQSKRAFPNIKRVVADAGY
                     KTPKFVHFLSHLKLYPILPYTAPHGVKGMFRKKDFVYDAYFDCYLCPNNQPLLFSTIT
                     RDGYRTYKSNPKFCVSCPLLENCTLSTKHQKIVTRHIWADLMDELEHQRHTALNREIY
                     KKRKQTIERIFADAKEKHGMRWTKYRGLEKVATHTMLTFAAMNLKKLATWLWKTKKPM
                     AFYFKIMQRLTKRSGLITNSFLSTI"
     gene            25158..26027
                     /locus_tag="JXV47_001162"
     CDS             25158..26027
                     /locus_tag="JXV47_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HAX1487217.1"
                     /translation="MKKKKFSRSLLGILVLVAVGLSGKGYFQNNSTQEHDFQIKSSVQ
                     VGNKADSESKEFLGIRYDPNKYPNNIVNINDGKYTLTKEDHEALSEKGSQTFWVNYAD
                     LDQLGRAGDVEALITYDAVNSHSSKNVERPSFKSSVHIAGEYKDGVFDQERDTWVGKD
                     SNNEITQLEGYKGYLYNKSHSLAWSLGGDMEVHNLTLGTRAQNVGKNDQNGGMAYSET
                     IVRDAIYKNKNEKVLYKVDPIYKGNELVPRGSHVEAFSVNDNGKTVNLNVYVFNNQKG
                     ININYQNGTWVRD"
     gene            26047..26394
                     /locus_tag="JXV47_001163"
     CDS             26047..26394
                     /locus_tag="JXV47_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487218.1"
                     /translation="METISINGLDKSVANRIKKGNGYYLLKKGKYSVARELETMSIVY
                     VAKNHFDVEQAIFDPDSEIGKCVELSEKTVSTKGAMIIEREMLDEIRVIIPKDTQMCE
                     DSISDDEPKSERK"
     gene            26407..27669
                     /locus_tag="JXV47_001164"
     CDS             26407..27669
                     /locus_tag="JXV47_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487219.1"
                     /translation="MSEKSIELKEYKRSDGEKYYPVASFSKSVYLVGRALVVGAIGIY
                     ILHWVTKVVQLLVDTLVSILVSLNDVNGTDDLGLKEMFKELLNAFFPNYLSYSYNVQS
                     FFAKLHLVDISILVLEAGTVFFVGYLVTLMFRHHYGEQRPFFDDMESRRLKREALEAM
                     DVKYDPNKIIGDETNNKKRKRNKTQLESDVLSTLKNIKISVHTRRDLSVNEDIREYIV
                     KIPQPKGKKVRETVLRQIQDLGSILTRATSGRAKFGEKEDEVSGDYFIFRASVNIERE
                     RKERVSTKNKETERATSSIAVSNSQFSFPINLFADNSKNIQNQTEKARKYAETQKQSL
                     ELYLSSADVPASLTDMHVGNTSIEYLFTLSRTRKIQLSSMKEEIETYLHISGVIVRIN
                     AGRIQITLPLGENDRIPIDVPSMINSVF"
     gene            27749..29125
                     /locus_tag="JXV47_001165"
     CDS             27749..29125
                     /locus_tag="JXV47_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HAX1487220.1"
                     /translation="MAMKLLEKVKKRAEKAESILLDKETNIKLNGKFSVNMLNTKAKD
                     PTDAIFGIKPDGTIAHFCISEMPHMLVAGTTGSGKSVLLNEILVTVMCHSTPDELKIG
                     IVDPKRVEFGRYKKLPFMLADPITDMDEAYDFFEYLVILMHERYKLMEKAGLQNITLY
                     NEYAEKNGLDRFPYVILLVDEYSQLVGTHKEVEGLIVQLGQMARAAGIHVILATQSPR
                     STVVTGIIKANFPSRVCLMVASDLESRIVLDEGGGESLSPKGDMLIKLVDGSMVRAQG
                     AYISNKEIETIFNHLRNTMPEPEYVDYRAIVAETRGEGGEDEDFGGIGKAPVRKSAKR
                     NLNTPLANPSSKEPSIEKKSAFAIKLEKNKEEKVEQGAKTLEKLQAEKLEKVLRALGK
                     ADPEPQTSNNTNNKQPIASKTKPKANDPKGSENVVITTDKSEKKQINGSTSPIMQKML
                     KAKKQVHK"
     gene            29122..29751
                     /locus_tag="JXV47_001166"
     CDS             29122..29751
                     /locus_tag="JXV47_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487221.1"
                     /translation="MIIVSSFLRWLTPYKYTDEVVVKRAKKRDKKAVLTPKQMLDHGI
                     LGVKVLEVNKPFESNSAREKLLGAEADVAYFYHDKSKHQIAIKFNPKSAWRYQARDDL
                     KRRKLRPMLYPEGKEAFDRTHIVPIGFHGTESDNRLLVGWNSNQNRVQINKFEKKVRK
                     FNDRKTILWFADICKQPDGTAKWEAVIFDENGKKVMSETWHDKAKFVWQ"
     gene            29770..30249
                     /locus_tag="JXV47_001167"
     CDS             29770..30249
                     /locus_tag="JXV47_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487222.1"
                     /translation="MLELFEANRTGFNQKLEVGETIEYKDKNYIIIGIYNTRINRIGD
                     PRITSDLVCQSVNYSPDLTSRYKKYVLLEYRHKITDEIGVNNTRNIFKIGTVIPYSNN
                     EEKIFYQIYGIEKFEYEHVDLLVTYQMRLIEPWSQAEIDKAVKLNRLSKFNVLGNAF"
     gene            30751..30804
                     /locus_tag="JXV47_001168"
                     /pseudo
     CDS             30751..30804
                     /locus_tag="JXV47_001168"
                     /inference="COORDINATES: protein motif:HMM:NF019230.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            30808..31407
                     /locus_tag="JXV47_001169"
     CDS             30808..31407
                     /locus_tag="JXV47_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HAX1487223.1"
                     /translation="MREKNKNSSRYLVATVVFVCVLIFLFDFLQIGKSIIGNTLSAKE
                     MVALGGLYEGHLFPNIFISIVSHINLYHLISNLLFLVVLEEALNDQYEWLTLLIVLII
                     SGFLGSLVPFLLHSNIVSMGLSGGIFGWIALFAIAYIRFDSKKHLLLSVFVLLIIGIL
                     LVSTFESGEANVLSHVIGFVCGMILGFILKNVSLIKQKN"
     gene            31423..31899
                     /locus_tag="JXV47_001170"
     CDS             31423..31899
                     /locus_tag="JXV47_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487224.1"
                     /translation="MPKRKEKKIPVFLSVSEMLSLQILLRKKIETIDEEVRNKRAMYE
                     QREALRERIHYFDDIHTKIYEARTNHEDESKLGLAQQRILEWLNTNTDQEPLRVISNL
                     FEFGTKHWFNAVEKDADLQEAFDTLSKDSKSMRDLLITYLNEHEFEQTKTKKKNKE"
     gene            31916..32818
                     /locus_tag="JXV47_001171"
     CDS             31916..32818
                     /locus_tag="JXV47_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487225.1"
                     /translation="MLLTLLGYLCLILAFFGAIAIIIGQFQTNNPIMRNIGIGIVIVT
                     FIVFNATKIFGSNDKQFGISGVNNSYAPDSLGRVVIDGTFENVTSYKNVSLTVKEDGK
                     KASDDVLATIKPSQSQFEVFYTVKENSPVHKLTLVFNVDGEEYYKDVKINKTSTKKII
                     ESAKKEVATEESTTESSSTVEAELPDKIDFDPEKVKSFESVSGSMADRFNTEVFKAIK
                     TVKLDTEKQMINVTLFNSVESMDQDKKVTVARELGKRVIGLYRGTAKPDSDGADLPVH
                     VVYEDGKVFGDSTANEALTIKLAK"
     gene            32891..33082
                     /locus_tag="JXV47_001172"
     CDS             32891..33082
                     /locus_tag="JXV47_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487226.1"
                     /translation="MVVNKEKVRKYVTLKIASVKYLEKRAKEEERARGKKVTVSELLE
                     ELIENDQTIRRAFTNRSIR"
     gene            33246..33833
                     /locus_tag="JXV47_001173"
     CDS             33246..33833
                     /locus_tag="JXV47_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487227.1"
                     /translation="MENNNDIRHFSIGERVTTVSELSKDYRDKEGTIISLNKNRRGVW
                     QYVVDLGDGVTVECKDSQLIRNNGSHSIEKAILVYPKVSSKIMNDWLLGKFGEYNKKE
                     IAEVIGKSYPTVLGYLKKITSKEAKIEDVLTVRELQSLIEYRNKQITNPEYLRKEDGL
                     LKQLEQVNKIRKMQKVAPLSLDTFKKIYLKEIKKD"
     gene            33833..34732
                     /locus_tag="JXV47_001174"
     CDS             33833..34732
                     /locus_tag="JXV47_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HAX1487228.1"
                     /translation="MWTVTLPFQPVSAPRPSARRNAADETNDVAEKRISTYYDKKYLD
                     YLKKIKSFIEDQDLLDDEFYSIVNDPMGAIMEVDFYYQIPKSYKKVYNIMKTTAPDLD
                     NLVKSAMDGIFNISAIRDSHITGLIAFKYNVANEGKTVVRIKRYSEFEWDTSEGLNGD
                     IWEATFDFKPVATPRPKSKFRGNGIITYYPKEYNDYLENIKNTLKEKDLVNDQLKKVM
                     NAPMGVIAQIDYFYQVRKDKKKLDSLMRTSQPDIDNLVKGTLDGIFNKEIGIKDSRVV
                     GLIAFKYNTFEKSKTNVRLQEMG"
     gene            34732..35646
                     /locus_tag="JXV47_001175"
     CDS             34732..35646
                     /locus_tag="JXV47_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487229.1"
                     /translation="MNNNEKILHVLDSFEIIQEELKKYRDVLEQRYDFVNQQKSNHMD
                     FILNMNDLKKKLVERKEQEKLIKAYFELGEKEVKNAMELNEERRVLDQLLEQLLVMFQ
                     KGRIDEDLIEEGLRKYPSNSGIGIVLKAIDEEEIEAFIPPEDFESAMEYIKYYSQGIT
                     AFREFDPEDVIHDLNNLKEWCESYGVDDSGLDYLISIMEIEEEMPDKPDPTDILELIH
                     EARNPIAYISRGYTVLEYYKPYISAMNHLRRVLREKREYRSVLNATNRLEKAVSELDA
                     YYREHYLQAGGMPRNTKANISRYIKKAE"
     gene            35698..35913
                     /locus_tag="JXV47_001176"
     CDS             35698..35913
                     /locus_tag="JXV47_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487230.1"
                     /translation="MKRDVFELYVLERLEDGMMAQEIIDEIDDMISRFGQLELNDGNK
                     NSVVLKQFWLNNFSYKDFIKEKANTLY"
BASE COUNT        13498 a         5003 c         7087 g        10604 t
ORIGIN      
        1 aatttcctag gaaaaatagt taacataaaa ggaatgaatt gttatgaaac aatatttaaa
       61 tgaatggaaa gcgatagagg ggtcattagt aacgcaaaga ataaaggaat tacctgattg
      121 cttagagaag gatcatttgt ttcaaatacg agaaatgttg aaaaaagaac agtttgatcc
      181 agaccaattt ttagtagtcg agtatccaac tattggagtg tactgttgta accatatcaa
      241 tgatggaaaa tattttatta ttcaggagta tggaggacag ttaactcctt tctatactac
      301 atgggaaatg agtgaagaag gaatcaataa ttttccatgt gaaagcatcg aagattcaat
      361 ttcacacacc gaatgttaat tgattataac tataaaaaag gattgaacat tatgttcaat
      421 ccttttttca atgaaatgtt ttccgccatt tcattgtttg gtgcgatttc tattttatta
      481 tatcaaaata aagagagatt ctaaagaaag aagagggaaa tatataaatc aagcgacagt
      541 atatttatta ttaaatgcta ttgtgagaat ataactaatt agtttaattt gaaagtaaat
      601 atacgctata aaagtgcatc ttgtgttata aaaaattatt ttattttgtg aacataattt
      661 aacaattctt tctcggaatt gatttctttt cttaaatagt cttcagactt attaataata
      721 ttatctatta tgtctagata catatcactt ttcgattcag ctaattcata cagttttttt
      781 aattctttat cctttaattg aaaaccctga tccatagtca ctgcatttgg atatagaagc
      841 ccactataat gtttacgtaa attcacttgg aatttctgat tataaaagtc taacagatta
      901 gaaataaaag gcggaaaatt actgtttttg taaaattgat tatttccatt taggttgtat
      961 agtaatttgt taaattgctc ctgatttaat ttattgtaaa tccatggtaa tacttccata
     1021 tccttatctg ctaacctgaa tgaactagca tcggtaagat gttcgatcat aaaatctatg
     1081 aacatctctt tttcaccaaa atataaatat tgattatata ttgtttctaa tgttgaagat
     1141 ggtagcgaag aaactctcat tttttgctgg agtataggat caactagact atttaagtga
     1201 ttttgtaatt cttcattgtt gtttcctaga actgcaaggg aacgtaaacg gtagtaatat
     1261 tctatttctg ttagtacttg ttgtttcggt ttaaaatcat ttattgatat ttgtaaattt
     1321 tgaattgtct cgtctgaaaa atcatgttgt aattctggat gggtagctat aaaagtaagt
     1381 aaaaagaacc cttttgtata cgtgatctgt tgattttcac caagtgattt attaatttcc
     1441 tctcttgatt cagctgtgaa cctatacttt gcaatttctt tttttagaat atttaaatag
     1501 aattctttat tatcaaaaat tagggcatta agtagtctga aagtactttc cctatctcta
     1561 tctgcttcct catttccata agataattga aaaacaaact taaaggctgt cttacatagg
     1621 ttttctttgg ctttttcgct tagtttattt agatagctat tttttagtgc agagtgaaat
     1681 tcttcaggtg taacagacat agcatgtatg cgacttgcat attgtataat ttcgatcgtt
     1741 actttttttc ctaatattgg attttttagg aatataattt cataggactt ccgtataaca
     1801 tcctgacaag tttcttttgt tatatctctt aattcccaag tattaccgtt gtaagtgact
     1861 acaggatgag ctgaataatt tctttgatcc ttaatatatt ttaaatcctc atattcatag
     1921 ctatcaatta gctcagttga actataagct ttttctagta gttccatttc ccattttgga
     1981 gagtttggat cactttttct tagtctagct atatcttcta aaattttctt agaagtatta
     2041 tcctcgtaaa tatttgctaa atcagataat ttatcaatta aatctaaaat aagcgcactg
     2101 taattgacag ctattgcaga acgataattt ccctgataaa aactacttct aacttcttct
     2161 aataatggaa taattctagg atttttaact ttttttattt catcatctaa tataaacata
     2221 taaatctcct ttttttattt gtatgacaag tttaccataa aaaaaaatta aaaagcgaga
     2281 catatttatg ttgttgtgtt atcataataa cataaatatg tagagtgaga tgatgaaaaa
     2341 atggatttga aacaatcgtt ttacatctgg ttatatcctg ataatcctat gtcaataatg
     2401 gctgatattt ttgtagttag catcttattg tatttatttt atctaatttt ctttcacaat
     2461 ttaatcgggt acatgattct tgattggaaa ggaatgttcg atatagaaag aaaaccattt
     2521 gctaacaatc aaacctatac cgtcttcgaa agtggagatt gggaagaaaa tgaagttgat
     2581 gtgatccatg aaattggatt agctttatca ggaatacaag atgctgatgt tttggtatca
     2641 atgacaacgg atactggata caacgcttat gaggtatttt atcttatgta ttttatatgg
     2701 cgtgatggtc aagaaattat caatggtcgt gctgaaaaaa caatcaattc taatactgaa
     2761 atttcttttt gtatgggtga aggggaaatg attgtatata aagatgggtc agcaaacatt
     2821 aaaacagcct ttggtgatat tgaaacaagt attaaggaac ttagggaata tgtgcagaac
     2881 ccatataatt ttcaatattt agcaggaaga ataaatttag tttaggagta aaaatatgaa
     2941 aaaaattata aatcaaccaa caaatcactt gataattgaa ggtgttattt tcgtaacaat
     3001 gtattttact gtaggaaatg gcatctcaaa tacaatcatt caaaaaaatc cacaatacct
     3061 attatttagt ctttatgctt ggattgtaca aatggtttgg gtttccatat tgatgctgtt
     3121 gttttattgg atagtacggg ttattctttt attgttaaac aaaagaaaaa aggataggtg
     3181 aataaaatga aatcaactaa attgaaggtt gtattgttat cgacagcagc attaataacc
     3241 cttacagcat gtggtacaac taatagtgct aataataaca aagacacaaa gtctagtagt
     3301 acgatggtta ctaaaaacag cactacatcg gcatcaacaa caatgtcttc aatgactgaa
     3361 aataatgctg aaaagtatca aaaatacgaa gacattaata aaggtcaaaa gccggatgaa
     3421 gtttataaca actttattaa tacagtaaaa aatgatgaaa attatgggaa tgatccattg
     3481 caaaataaaa atctgactat cgttctttac aaacctgatt gtccagattg tcaaaaagca
     3541 gaatcaaaaa tcatgcaaga aataaaagaa ggatttagtt atgctccaac attaatgcat
     3601 gatattacca taaataaacc agcttacgag tattacgcag ttgctgtaga tattactgat
     3661 ggtgtacctg agtgggtaca aaacattcct ggtctggctg atgagaacaa tcaatatcat
     3721 acgccaacag ttgcagtagt aacaccaaag aaagttaacg gcacactata ctgggatgta
     3781 atgggaatga caacaaatac aactgatgaa atgattgaaa gtacaactaa atattatatg
     3841 gatttgggag catataaatt atatcaacaa tcagagcctg ttatggacga tcaatccaaa
     3901 gttaaataga tctttagggc gtaagcccta tttttttaaa attaagtgat aacaaataaa
     3961 tgatttctga aacaaacgtt cttactcaac tactcgaaac acacaagcta attaactaga
     4021 ttataaagga gaatgcgtaa tgaaagaaat cagtgcaaat gaagctcata ttccgcaaaa
     4081 gaatcaggtt ggtatatata aggtgcttca tggtgaagga atttataaaa tacagttact
     4141 taccggttac aataatggtg caaatgggaa gtggttaaag gcaacaagta ttcgtgaact
     4201 tagaagtgaa gtagaaaaaa ttaggcttgg tctcacaagt gaagaaatag ctaaactgaa
     4261 gggaaataat tcttttgtaa ttgaaaaaga aaaggaaaaa catctacttt atcgtgagct
     4321 gaaaattgaa gaatactatg aaattgattt acctgaaaaa ttaagaatta ttgatcaacg
     4381 ttcagaagaa aaatggaaaa ctgaaatata tccaagctta aatgactaca agacatcagg
     4441 aaagcccatg tataactaca caggcttttt aacctacaca caatacaaat atgcctttcg
     4501 caaattaaaa ggcattaaac aagctgaaat tgccctgtat gagatgaaaa aagtggatag
     4561 attgaaattg attcaagatt tagtgcaaaa tacatggaat caagcgattg tcgagctaga
     4621 aaaagaaaat gggaaaattt taactaataa atatctgatc gtaaatgaaa ttgaagaatt
     4681 aattggttta ttttcatgtg aaaaaggtga agtcttcttg aagtcatcac caacctattc
     4741 aattttggac agtccgtatc agtttataca ggcaaggaga tgagttagat gtctagcttg
     4801 aaagatgact atatccaagc aaaacaagag tatgaaaaaa tacagatgtt gaaatctgag
     4861 aaagtcgaat tatttttaac acaaaaatta gcagaggatc atattgctaa cttagatgct
     4921 aaaactttag aggaatatga tcggcagttt aatcagatac atcacaatat cattttgctt
     4981 gttgagcagg caaagcgaag gtttgaaaaa gcggaatatg atctattaga tcaaggaatt
     5041 gtatgcttgg ataagggatt gcgaagatat tatggtgcag agttaaaaaa gcaaaatgta
     5101 gatagaaatg cactaaaaca tgaaatctta gaattgataa tgcaacgaat ttgaagggat
     5161 agaaagcaaa tgtcacaaaa cattagtgct gtaaaacaat taatagaaga agatttagag
     5221 accacagttc agagattagc ggaacgaatc cattttgcaa attatcaaac catctctaac
     5281 tggtcaagca ggaacagaaa tccggaagaa attccaatga aattttttta tcgaatcgga
     5341 aaagaatatg gtgttgatcc gataaaaatt ttcgagaaga ccatgattta ttactatcat
     5401 ggaacaccta acgaagtgtt agaacatctt ttggaagagg caaaagaaaa atcatcaata
     5461 ttagagctat cgcaaaatga caaagttatt caagtgaaat gcgttgatcc aacaggaaag
     5521 attattgtcg gttttgatat tgaaagaaaa tccaaaatag attttattac acaattaaaa
     5581 aagataaata atttagatat tctaacgctt agaccagatc atgaacagtt gtttatgagt
     5641 tttaaaaaac aattgaaaga aatacaaaaa agatataaca aggtgtttcc taatgcgtga
     5701 aaagctcaaa gaaatcagag ttttttggat aattaacaaa gaatgtatca tcttatatac
     5761 tcttggattt cttagcatga tcttgttttg gtggttatat ttaaaacagt aattggagag
     5821 ggtcaagagg atttttatca agataaggat gtggaaactg catgtggaat aatagattaa
     5881 aaacaggatt gttattaata gttatttcct gcgctatgat gattggtatg aggatacaaa
     5941 gggaacaatc ctattttgaa gtttctgcta acaacgtaat agaaaaatgc tattacggtc
     6001 aacattattg gagtgaggaa gtcagagaaa atatagatcg tgaatatgtt caaagaattg
     6061 tttgggatgc atattctatc aaagattatc ctaaaagttt aacgagtaga ttattttaca
     6121 gtgaaaaaga taatcaaaaa ctctcagatt tgatgatgaa aaaagtatga ctattattac
     6181 gaaagagaaa cagagtgcta tattcgaggg gaaaaagcct acaacaaaag tgactattgg
     6241 ggtgacaagg cgaagcgatt aactgcaaat tttagagtgt atgaatcaga gtttataaac
     6301 ttgacctttc ttaatagtgt ttttattgat tatgtaatta ctacgaaacg cattggaagt
     6361 tattcaagta cctacgcatc cttagttcca atgttaaact cgatgagccg tttcttaaaa
     6421 gaaagagaaa agaaagagct acagtatatc aaagaaatca tgccggattt tgaaatgcac
     6481 gaatggcaaa ttgctttatc agattggaaa ttggcgaata aggttcgtag aataacacct
     6541 tttcaagcca agcgcttttt gagagctatg aaatttgtgc aataaaaaaa gccaccagac
     6601 aagttgatgg agactaacac aattaccaac agttgtaatt gtgttagctt acaaattaat
     6661 tatggtgttt agtcaatccc aaattgtgaa atggcaccaa taattggaaa ggaaaaatga
     6721 aatgtctgaa gatttacgag agctgaagtt acgaaagaag cagtatgatc agtatttttc
     6781 cggtttgttg aataaacata ttgaagaagg acttgatcat gattttggaa aagatgaata
     6841 ttgtttatat tgcgaacgtt acaatgaaaa aatgtctgaa tatctacagc tgaaaaaaga
     6901 gatacagaaa ttagagaaaa aagtacatgc ttggaagtat aaagattcca tgtctggtta
     6961 tgttgaatct caaaataagc caagaaaaaa gaagcaagcg tatgttctaa agatggtaaa
     7021 tggggaagag ttaattgtat tagcgtacag tgaagaagag gttcgagaac tcgttgaaac
     7081 acctgtcagg aaaaaggttg aaacaataaa tgagatagac gacagccaat acaatagcat
     7141 ctatattgaa acaagtcatg gtggatataa gaaattagca actttcctta gaagttctaa
     7201 agttgggata atttctaaaa aagacataag tgctgttacc gatagttttt gtactttatc
     7261 tgttcctaaa gcttatttcc aatacgatag taaaagattt gaacgcttag agaaattctg
     7321 tagaccgtat actgtattga aaactaaaaa atttaataaa actaaaagag tttctataca
     7381 gttaccgact ggtcaaatct cattaggtga aaaagactat ctgataaaag taggaaaaga
     7441 gttaattata aaagtaccgg aacacttatt taaagaaaat tttgagatac gtgaaacctt
     7501 ggtatggaaa gaagaaaaat agtttggaag acatagaatg gtataagggg aaattgaaat
     7561 ggcagtaaat aaaatattgc aggtactaat catagacgaa tttggcggag gagaatggtt
     7621 tgatgtgcag tccatagact ttgaagaaga agtcgtagtt atagaaaata tttacggcga
     7681 agtatattca tattcgcttg aaggtgagaa tattgaggat ttacggttga ttggtgagta
     7741 gaaaaaaaca gaaatatcaa aatggagata aaaattaata gcatgtaaag atagtcatgc
     7801 ttgggttaaa aatgttaaaa ttcaaaaaaa tgagtcagaa gggataaaag tatgaaaaga
     7861 gaggaataca aacaaagatt aaacgaactg cttgaagagg acgaaacatt aactcatggt
     7921 tcgcctgatg aaattctata catgattgat aatatggtga tctttggtgg atatgaactt
     7981 ggtaataggt cagttgatca taatatttta gaatttgatg atgtatcatg ggaagaaatt
     8041 cttgattggg gaattttggc ggtacctgaa actaaaacct atattagtga cactatggtt
     8101 cctttttttg aggaattgga ttataaaaga cttcccaaaa atgaaaatca tatactggga
     8161 ggaaactaac aatgttaagt gacttattta ttttactgat ctatctaggt gtaagtgaaa
     8221 ttattgcgta ttttttgttt gtcattgcta attatggtat ttccagtgca atcgttcaaa
     8281 tgtttagatt accagtaagt gaactaaaaa aatgatgaga ttatcagcat atcttttaat
     8341 gtttttgaat gtggtcacgt taatctttgt agtaatcggt gtgactttcg atttaatgga
     8401 atagtgggaa atctataatg gaaaaaagag acacgaatga acatattttt tgaatcaata
     8461 ttgttgatgg tttttgcgat cagcgcttac cagaaatcta aaaaagagta atgattgttt
     8521 aatcatcact ctttttttgt agggaaattg aaatatgtgg agcttgtatt ggtttagtta
     8581 ggattgcttg gctataagga gctagttctt tatcaaaacc atcaaagtag gttttcagta
     8641 gcgatttaac tgatcgctca tcttgtttga tttggataat ttcagcatcc aaatcggttg
     8701 tgagatcagg agcttttgat gcgattacct gatttttttt atcttccaac tctcttaggc
     8761 tgtttaacaa gttgtaaaaa gaatcatttt gattgttcat tccaacgtga gttgcaattt
     8821 taacagaagt ttcgtccgta ttgtcatcaa aagaactcat tggaatatca agtagtaacg
     8881 aggatgtttc ttttactgac tttttcttta cagcattttt tgtttttcca tcttttttgc
     8941 tctttactcg agatgttttt ggagctagtt taggtaaatc acttgtttta tcagtcattt
     9001 attagctttt cctttctatt aatttatgtt attatattat cataataaca taaaaaagta
     9061 cactttttgg gggcgtagtt attgaaaaaa tctaagagaa agattgccac attgcttatg
     9121 ttaatggtgc aatttacagg gattgcaatg agtgtaatca caataaatcc gcaagtgata
     9181 catgctgatg ggatagctac ttatgatgca caatttaact gtactactga aggtagtggg
     9241 tcaggaacag atagcgatgg aaacgatact ggaagtggcg ctgtaacagg tgatgtagcc
     9301 aaaaatattg aagatattta caaatacatg aatggagaat atggcttatc aggtgctagt
     9361 attgcaggta ttttaggtaa ctggaaacaa gaatcaggta ttgatcctcg agcagtagaa
     9421 gggtattacg gagatggaca gagagaagtt gacttcatca aacaatttac tgatggtctg
     9481 atgggtattg gctatggtca atggacagct gggcgacata cagcattagt tgattggtct
     9541 aagaaaaata atggcggttc ttggtggact acagaagccc aattggactt tatgttcaaa
     9601 ggtgatgggg gattcgtagg aatattaaaa gattatgctt taaatgcttc tgatgatgtc
     9661 gtagaaaatg cagtaacttt tcataaaaac tgggaaattt cagctgattc cgaatcagct
     9721 gtaatagctg tacgtggtga aaatgcaaaa gaaatctgga agtacatgaa aagcaagggt
     9781 atggacggtg caaaagatga aagtaagatc aataaaatat ccggaggttc aagtaccgga
     9841 gatggatcga ataattcatc aagttcagca tcaggaacag tagaagatgc ctgtgcaact
     9901 acggatgacg ctaattctgg ttctggatca attgggaaag aaggaaaaat taacggtaaa
     9961 aaaggtcaag taatagcgaa tatgacttat gaagaagctt tgaaaaaata tgggaaagcg
    10021 atcacgctac caaaattcaa agaaccagat tggtcaactt caccttttaa cggaatatat
    10081 caaggtcagt gtacagagtt gacgtgggct tatatgagcc aattatacga tgggaatcaa
    10141 ccgactactg gaaatggtgg ttatgtatgg gaaagctaca aatcggcagg agcaaaaata
    10201 acgaacaaac caatcgtagg ttatgggttt agtgcttcgg atggatggtt atgggctgtt
    10261 ggagatgcag ggcatactgg tgtagttata gcggtgtttg aagatggatc atttctatgt
    10321 gctaacttta atgttccacc aacccaagct ccaacaaggg gagtttcggt aacgttgatt
    10381 gatggagtgg acggatcaga taatgtgcat ttctttagcg gtgtaggaaa agctaaattt
    10441 gaaatcgaaa aataaattgg aatgaaggac gatatagatg aatagtaaag tgaaagatac
    10501 aattatcatt tctttgcttt ctggtatgtt attagcactg cttgttggaa tcctattctt
    10561 caataagcag aatcaggaca tagaagctga aaaacacagt gtgcatattg aagataagct
    10621 gacattcttt aaagaggtta aaccaaatga ggtggatgga ttacggaaag atttagaaaa
    10681 tgatattcaa gaaatgttga atggatcagt tcaaaataag tttgcagatc aatcaggtga
    10741 agaatttttg agaaaactat ttattgtaac aggtaaacca ccaattactg ataagagtag
    10801 tgagaaagaa aaaatcgagt actataagcc ttttactttt aagctaacaa actttggaat
    10861 taagacatct agtagtgggt tgtatgaagc attgaccgat tttgaagttc aatacaatgg
    10921 aaaaaaagtg tatgatacca cattaaccat cacactaaat aatgataaga aagtgactgg
    10981 gggtgctttt tatgcaaaat catgaaatca ctactgctaa aaaggcgatc ggaatacttt
    11041 ccataattgt gatcctttgt tgtgtggtac tatttcaaaa gaaaaatgct tatgataata
    11101 atgtcaaaga attggaagac cttaaaagta aacaaatcga agtagtcaag aataaccaga
    11161 aagtgaaagc tatgcaggaa gctcaataca aagaattggg aaatgctgaa attaaggaac
    11221 aaagtaggaa attctttaat ttattttaca actggaattc atgggaaaaa tatacgaaga
    11281 atatgaagga aatacaaaaa gaatttcctc agatagtaaa gtctagtcct gttgatattt
    11341 ctggcacgat ggtaggcact ggtaatagtc caatatctag ctatactgct gattactata
    11401 caacaaatca aaaaggtaaa atggttgaat tgattacaca gacaagaaat actccaacaa
    11461 cagcaacaac aacaatttgg cgtggagtaa caagcatagg agaaaatcaa ttgttttatt
    11521 tggaggattt agatagctat gtaagagcag agtaaaataa aaaaagagct aacggtacca
    11581 acgttagctc tttgtgctga cgatgataac aaaacctacc gaaaaaggat tgtttcatca
    11641 caaacacaaa cagaaaagaa ttgataaaaa acccgaacct cagaattttt attaatcaat
    11701 tcatttagat tataataaat tgagctgaac attacaatac gtatatgttg taaaacgtaa
    11761 aaaaagtcaa aagtaaatac tttcttaaaa agtcaaataa aactattaaa gacaatatat
    11821 atggtttatt tgacataaga aaatggtcta gatgataatt gtaatataga attgtagact
    11881 taaataaagc ataaaatacc ttttatgata aggtatagct cttaatttta agcagtttta
    11941 gatataagat tgaaagtaaa gtgggggaga ataataatgg cagatcataa attagaaaag
    12001 ttattagaag aaacgtggaa tccaaaagaa tttagtgaat tttttatgga gaattttgaa
    12061 actgacttag cagtgattgt taaagatgct cttagagagc aagggtatcc tgaaactgca
    12121 aactatataa acattaattt tactttgtat actgaaaata aaggaacttg ggatttttgg
    12181 gctactttag caaataagga gttaagtgat aaatcagaca caggaattcg taactttttt
    12241 gaatcaaaca gagatgatta tatgtatgct aacaatcaaa ataaattgaa ctttagagta
    12301 gagtttgatg aaacacctga agaatttata gaaagacaac cgcctaaaga aaatgtagca
    12361 aaggtattgg aagatcgttg gaattcagat gaaatagttt caacaattag cgaactaggc
    12421 ggacaatatg aaccgctagt agaagcggtt agagaagagc taagactgaa taagtttcct
    12481 gatgttcaaa atattgatgt ttctcaaatt gaaataaacg tcaagatcac gaataaactt
    12541 gattatggta gttgggcaga tatagcatta gaaaaataca tctactcaac gttaaaagag
    12601 tttatcgaaa atagaatgga tatcatgtat ctacagcatc cacagtattt aaactttggt
    12661 gttgaaatag ctacacctct tgaagaatgg aaaatggagc aagggcttga ctagcctttg
    12721 ctccattttt ttattttaca aatgaataca gttcgtcgtt tttaccaaga atgattgttt
    12781 gcccaacttt gagattgtca ggtgatcctt cagcggtttg taaggagaac gttccattga
    12841 acttatcgga taccgttata ggtagcttta attctgatcc ttcctcatct ttgagaattg
    12901 ctgtttttcg ttcatcaaaa taaacagtct ttattaaata atttttcgta gtgatctcag
    12961 cagatttgtc tttttttgta gtagtaccag tttctttaga attagaggta ttttctacga
    13021 ctattccatc tttggcattt gagcttgtgt ttatttgatt gaatattttc agcgacaaga
    13081 taacgctaag aatagtcaat atagaaacaa gtgtaattaa tactgataat ttcctttttt
    13141 tgttcatttt ttcttaacat ccttttttgt tttgattagt tagatattcc ttatctaaca
    13201 agccttttta ggctattaaa tgaagataaa ccccaaaaaa atattgcaat tatgacagtg
    13261 caatggtact attattatac aataaatttt gcgaaagggg taggtctaaa tcgcaaacaa
    13321 aaagaaattg aacctagaca aatacaactt gtataccgca agggaagcaa gtttgatttt
    13381 gggtaaaggt agaaattatg ttacaaacat aatcaactat tatccaaatc gtttgcctaa
    13441 aggttcgttc aagaaagtgg gtgacaaaac ctatattata acggaagaag gaatagaagc
    13501 attgcgatca caaacagaaa ataaaaacaa aaagaaggaa tgaatatgaa gagaaattcg
    13561 cttggtatgg ttttattggc atcagctgta cttgcggggt tatcagtacc agtaacctca
    13621 catgctgatg aatggactgc aaacacaccg gatcaaatcc aaattacaac aggacaatca
    13681 agttatgcgt tcaaaaaagg agatactatt tggtcaactg tagagaagct taaaagctta
    13741 ggttacaaga ctactgttgc tgagtttgcc gaattgaaca atgttgattt ggcaaaagga
    13801 gaacaacgga ctatcccgat tggacgaact ttcaacatca gtaaagatac attaacagtt
    13861 aaggaagcag atggcgaagt agttagtcaa actgttcaaa aagataaacc tgatcctatt
    13921 gaaaatacgg agcaagagaa caaaaaatcc gagactacaa aagaatcgga accaacagca
    13981 aacacttctg ataagacaga aacaagtgct tcaagtgttg atggagcaag ttcatctaat
    14041 acaaataatt ctacaagtga gaaagaagca tcacagggaa caagtgaaag tagcactacg
    14101 gaagctgata ctggaacatc aacaaataac tcacaatcaa catcaaatga tgcaaatgaa
    14161 tcaaccagta catcttctag tgatcaatca caaacaggtt cgagtgatga aactgacagt
    14221 tctacttcac caagtaaacc cgaacaacca actaatgttg tgctaggcgt tccatttatt
    14281 agtcaaggta acacaatgct ttgcgaagga acatctttgc tagaagcgtt acattataaa
    14341 ggtgttgcaa caaatcaaga tttaatgact tttgttaaat caatgccact atctcctgac
    14401 aataatccaa ataatggttt ttctggtgaa tggagacaca atgtggatgg aacttatcaa
    14461 ggtatgaatc cggctcctgt agtttcatgg ggtgttgcta atggcggaaa tgttgtagat
    14521 atttctggtt catcggtaca aggattaaaa gatgagattg taaatggaaa tcctgtagta
    14581 gcgtgggtaa cttatgcctt tgaacctgct caacataaac caatgttttg gggcgatgct
    14641 atttggaatc gacatgtagt agccgttgat ggatttaaag acggttttta ccatgttgtc
    14701 gatcctgtgt ttggggcaag ttggattaat gcaggatcat ttgaaacagc atataacgta
    14761 tctcaattag cggtttcggt acgttaataa aagatatcgt ttatatacta agtagttata
    14821 tagtctttat ttgtccttgc ttaactactt agaaaacttg ttgctcatgg tgggtagaac
    14881 taaaaggggt gatgctatga atactagagc gttgaaacag cttgctttca acgaaaaaaa
    14941 tgattaatag gtgtggtgat tttaacttag gaatgggcgc gaaggtcatt accacaccga
    15001 catatcgtgg ctcattttct tcgcctaact ggtataaaga aggagtaacg agagatgaag
    15061 catgaaaaaa cgataatttt aaaatcaaaa ataatttatt gttttgcgac tttagtaatg
    15121 atgttatcta cgcttataat gcctttttca gcaataagag ctgaagcaga tgtcacaaaa
    15181 ccgacaagtg caaaatttat agaaactggc gtaaaaacag acggttatat tagggttaat
    15241 atgccgaatc atccaaatga atggatgatt tcaagtcaat ttaaagattc tcatggaaat
    15301 attggatatt gtatggattc agaattgcca tccccaacag gaagtggagc cggaagcttg
    15361 aagtacaagg gagctggcag tgatgagttc tatcgtatgt ttaaaggtgg ttttccatca
    15421 aaaacagcaa aggaactggg tgcaggaaat gatacagaag catggtatgc aacacaatta
    15481 gtttcatggg ttttagccgg aaactttaaa gtttcacaga ttgtatggtc acatccaaac
    15541 cataccgccg cagaaacagc tcgtgtaaaa aaagcatttg aaaaaattta tgactatgct
    15601 aagaatggaa aagatacgcc caacactgag ttttctatca cagcttctaa gacagctgac
    15661 gaaggaaaat atcacacttt cacatataaa acagcatcaa ataagactgg taatgcgaag
    15721 ctcactttta catcagcaaa accagctggt atgaagattt atgatgcaga tggtaaagaa
    15781 attactaaca acactgtgaa attaaattca agttttacta ttaaagtacc tgtgactaca
    15841 ccaagtggta ctttgtcatt taaaggtact gctaatgtta gcacaaccaa tccttttact
    15901 tttgatggac gaggtgtgta tcaagatgcc gtagttatga tcactacttc agaaacaaag
    15961 gactctaaat ctttgagtgc taaatggaca agagctgttg gtcaggtaac agttaagaaa
    16021 gttgatcaag atggaaatgc tttaaaagga gcggagttta ctctaactga caataacaat
    16081 gctaaatctg ttaagacaac cggagatgat gggttagcta cgtttgattt gcaacaaggc
    16141 ttaacataca gcttagaaga aacaaaagtt cctgaaggtt atcaaggttc atttaaaaag
    16201 gatggtatta ctgttaatac cgatggacaa gaatttagtt acactgctac gaacacaatt
    16261 aaaaaaggta aagtaaaagt taaaaaggtt gaccaagatg gaaaaccatt agctaatgct
    16321 gaatttacct tgacggatga ttcatcccaa acacaagcag aaaaaacaga tgaaaacgga
    16381 cttgcaagct tcgatattgt agcaaacaag acctacagcc ttgaagagac cggagtacca
    16441 actggttata caggcgtatt caagcaagaa ggaattaccg ttaaagatga tggacaaact
    16501 tttgaatata cagctacaaa cactttgaaa aaaggtttag taaaagttca taaagtcgat
    16561 caagatggaa aacctttggc aaatgcagag ttcactttaa ccgatgaaaa aggtgcaaca
    16621 caagtagaaa aaacagatga aaatggactt gcaagcttca atattgtagc aaacaagacg
    16681 tatagcctag aagaaaccgg agtaccagta ggttacacag gtgcatttaa gcaagagggt
    16741 atcaccgtta aagacgatgg gcaaactttt gaatatacag ctacaaataa tttgaaaaaa
    16801 ggtgtagtaa aagttcataa agtcgatcaa gatggaaaac ctttagcaga tgcagaattc
    16861 accttaacgg atgaaaaagg tgtaaaagaa gttaaaaaga cggatgcaac tggtctggct
    16921 acgttcaaca ttattgcgaa caaaacttat aacttagaag aaacaaaagt accaacaggt
    16981 tacacaggcg cattcaaaca agaaggaatt accgtcaaag atgatggaca agtctttgaa
    17041 tatactgcta aaaacacttt gaaaaaaggt gtgatcaaag ttcataaagt ggatgatcaa
    17101 gggaaagcat tagcaaacgc agaattcact ttgacagacg acaaaggtgt aaaagttgta
    17161 caaaaaacgg acagcaatgg cttggcaaca tttaatattg ttgccaacaa aacgtacaaa
    17221 atcgaagaaa cacaaaaccc taatggttat acagggaaat ggtctaaaga aggcatcacc
    17281 gttgctgacg atggacaaac ctttgaatat acagtaatta atcaccttgt acctgaaaca
    17341 gtaagaacag gcggaatcgg tacatcagcc ttccttcttg tatttctaat tgcaggattg
    17401 agtatggtgc tactgtatta tcgagaacag cacaaagcaa aataaaaaag tgttaatgga
    17461 aaagaagtaa atatgaaaaa agaaggctga cgtatgaaat caaaaaaaat tttttcaaat
    17521 ttaatgctat ttggtacttt gctaggagtg ggattgggcg caagctcaat ctcttctagc
    17581 cttggactag gggggcaagt agcatatgca caacaaaact ataattatca aggaactgga
    17641 acgattcata tccataaagt aacaaatact aatggggatg ggaaccctgt ctcagatatt
    17701 gataacaaag ggaaagaaat agctttacca aatggtgtaa aacctcttga aggcgttgag
    17761 ttctcttatg tgaaacttac taaagatgaa gctaaatcct tgggatggac ggatagtgat
    17821 actacaaaag gtcaacatat tgatgatgct aaagcacgat tattactaaa caaaaaatac
    17881 agtgaagtaa gtagaatgaa gactgattca caagggaata tagacatacc tatacaagta
    17941 aatacagacg atttaacaga taacttgtat ttgattgttg aaacaggaac agtcaaaggt
    18001 gtagttgaag aagcgtatcc tatgattgtt aacgtacctg aactaaacgg atcagatgat
    18061 caatacttta attatgatgt acatgtctat cctaaaaact atttccaatt aaactcagca
    18121 gagcttgata aaaaagacga agatggaaag gctcttgccg gaactgtttt tgaattgcga
    18181 aaagatgatg gatctgatca ggttgttgga acttataaaa cagacagcac aggtaaatta
    18241 actgtagatg gtttggaatt aggtgactat tatttcctag aaaccgattt gggaacagat
    18301 gctaataaaa caacctattt actagatggt aaaaaattca aatttagcgt taaacgtggg
    18361 gagactgcta aagtagttct tgatgttacc aactacaaac gacctgtaat tactaaggta
    18421 attgataaag aaaccgttga tactggcgaa gatgttcaat atacattgaa accatcaatt
    18481 cctggtaata ttggtaatta cgaaaaatat gttgtcaaag atgttctagg tgcagagtta
    18541 acttatgatt catcagaagt gatcgaagga atgactttag atactgatta cagtatcgaa
    18601 cgtgacggac aaacgacaaa ctatgtcttt actgaatcag gtatggataa gcttcagaaa
    18661 caatttgatg caggggatcg cttctttaca attttgatga acgctcatac taatagtaaa
    18721 gctaaaatgg atacaccact taagaatgat gtttcaacga tctacaacaa tggatatgaa
    18781 cccgaagacg aaacaccagt tgatcacgct tatacaatca ttggtgatca ccaattcatt
    18841 aaaacagatg gagatacaag caaagcattg agtggagcaa aatttgtagt gaagaacaaa
    18901 attgatccga ataaagttac ttacctaaaa caagatccaa caacgaaatc tgttacttgg
    18961 attgcagata aatctaaagc tactgaattc gtttccggat cagatggtaa gttccaaatt
    19021 gaaggcttgc aatataccta tgatgtagat tttgataaac aaggtaatcc aacaatcaca
    19081 gataaaaaaa tcaatgatta tgctcttgaa gaagttgttg ctccttcagg atatacacca
    19141 actagaaatg atgttccatt tgtggtatcg aatgatgatg cttctagcga agtaacagac
    19201 atcaagaacc ttaaaacacc tgaaacagtt cgtacaggtg gaattggaac agtagtattt
    19261 ctagtggttg caggtgtggc aggaacaggg ctatatgttg tctacaaacg agaacaacac
    19321 aaagcttaat gaaataaaat tccctagagt gtttttggct ctagggtttc tttttaaaaa
    19381 gtgtgtgaaa agtaggtatg agcatgaaaa agaagaatat caagttgatc atcttaaaaa
    19441 ttgggatgtt gctatgttta ggagtaggtc tatatcctgt aattactcag gcttatacct
    19501 actaccaaac tcaacaaaca ctaaactcct ataaggaaaa atatgatgaa gcttctgaaa
    19561 aggagaatga agaagtcttc aagagatatt cagaagttaa taggaaacga aaagacacag
    19621 aacaaacctc agtcacgatt cctgaagata ataacaatat tccgtcaaat ggaaatcttc
    19681 agaaggataa attaggtgaa ttagtgggtg aaattcttat accaaagatt aatgtggatt
    19741 tgccaattta tgatggtgta aacgatttcc aactatcagc aggagcagga atattaaccg
    19801 gaactgatta tccaactggt gggattggaa accattctgt tatatcagct cattcaggca
    19861 ttcctaataa aaaatatttt acagatttag agttgctcaa acttggtgat aaatttttta
    19921 ttgatatttc agggaaaaaa cttgcttatc aagtagatcg gataaaaaca attctaccaa
    19981 ccgaatttga ggatttgctt cctgtggcag gaaaagatta tgtaacactt atgacatgta
    20041 cacctgttgg agataattct cataggttac tcgttagagg ggttagcata ccttaccaaa
    20101 aaagtattgt tgagaaagaa aagaagaaag aagatttaaa ggtaaaggcg cagatgaact
    20161 ggtatcctat cgtagttgta ggggttttat taataatagc tgtgatagtc attattaaaa
    20221 aaatagtagc aaagagacga ggaatgaaaa atgaagaata aaatactact ttttttgact
    20281 cttatttgca ctttggtttt aacaatttat cctgcaaatc agctctatca tcaattcaaa
    20341 acaaaagaga atgtggcgga aatccaagag aaaattgaga aaaaacaaac tccttcaaaa
    20401 gaggaagtgg caaaaaaagt cgaacaaata aaatcgaaca gcggtaacca aggattagac
    20461 aatactcaga aaacagataa aggagtagac aatactcagg aaacagacgg tggatcattt
    20521 gatattcgtg aagctgaagg aaaggtcaat ccatacacag gagatgtttt ttcaaaaaat
    20581 caaacgaaag attttgaacc atctacctat tcaggagcgg ttggttatgt ctatattcca
    20641 aaaataaatg tgctagagct tttgtttcta ggcgcttcac aggagcattt atatagaggt
    20701 gtggcacaaa tgagtgctac tagtctacct ttatcaggta aaggtcatca aacagtaata
    20761 gcaggtcatc gtggcggtta tacgtcacca caatttcttt atgttgatca attagtagcc
    20821 ggagaccaca tttatataga ttatcttggt gaaaaagcag tttatacggt tttccgaaca
    20881 gacgttatta gaaattacgg tcagaattca acactgactg atattcctga tttagatatg
    20941 ttaacacttt atacttgtca tccatatcct cagaactacg atcgtttatt agttagaagt
    21001 ctaagagatg aaaaagcaaa atacatcacg ccacaagtaa cagttggcaa taccgcatac
    21061 gctgatgcca ttgatagcga gtccgtttca gataagacag aaactgttac atcttctaat
    21121 gatttatttg aagatgttga tcgtgccaac aaggaattag atggaaataa tgatcttaat
    21181 attccggaac aaggtagcgt agagatgcaa gacagaacgt ttgctgaaaa ggcaagttca
    21241 atatttacag gaattaccaa taaacatcag aaaatgcttt tagtcatttg gactgtaata
    21301 ggagcattag caagtctaaa ggttcttatt cttttaatca aagagtttcg aaaagcataa
    21361 tgaagattat aaaaattgat agagtacagt aaaaagggat tgatactatt attgatctct
    21421 tttttatttt gaatagagct agattcactt ttaaataaaa tcaaaactga tcttaattct
    21481 aaagaaaaag tcaagaaaaa aatacaataa atttttttat cagaatattt atcagaatat
    21541 tattagaaaa gataaactca aaagcttaat ttaatagggt tattggttgt atttagaaat
    21601 aatgtatgga aaagctataa agcaatagat aagatgtaga aaatcttatt tgtgaatgaa
    21661 aaacaagtca tcgtaaaata ttaataggag gtgtagtaat ggtgggagta tcaaaaacag
    21721 ctttagactc attagctaaa ctatttagta gcaggtttga tggtgcagaa tttgttgaat
    21781 atctaagcca aaacgaaagt ggaaaaactc tgatcgaaac aatgaaaaaa gactatttga
    21841 atgaaaatga ctttccgaca tggacgaata ttgaagatgc tacatgggat gtagtatgta
    21901 cgatatattc tccttgggta acgattgctg attttgtttt agataaaatt ggaggggata
    21961 cataccctga tgccaaatct cttgctacaa gtgactttaa aacgttctat ggttatctaa
    22021 taggtctaat aggcaatgga atagatttga aagttacgcc aaaacaaaca cctgaagaaa
    22081 ttgaaaaaga aaaaggagag gttcaaatgg cttatgcaaa tgacagagaa aaagtaaaat
    22141 tattggaagg taaattatct gaagaagaac ttggaaaaat ggtgcaagaa atcaatgaag
    22201 acagcaacta ttttcctgaa ttgaaggtat atcaaaatga cgaagatttc tttaatgaaa
    22261 tgtttagtaa tagtccatgg gaagcagtaa gtaaaacaaa tttaggagaa tggaactttc
    22321 aagatgatct agttgcattt agcaatgatg ggtatttacg atcatattca gaaagtgagt
    22381 atagagctga attaaaaacg tatgaaacgg atattctgat gagctattta aatctattag
    22441 agagtggtca gggagagtta agagataaag ttgaagaact attaaaagaa gagctatagg
    22501 gattatttca acataaacac aagcagaaaa ctaccaaaca aaacgtacca tgcaaaaagt
    22561 cggttaaacc ggctttttgc tctattatga gaggagatca aaccatgagt gcaacaaccg
    22621 atatggcttt agaagcagta ataaaagata atacaggaaa tgtcgaaaat gtagaagact
    22681 ttagcgatat tgcaatcaat ctttcagcat ggatttcagc tgtaggagaa gaaaatatcg
    22741 aatttgagat caagaatatg gatgacttaa aagcaaaatt tccttttatt gcatcgaaac
    22801 taagtcaagt tgccgaggat aaatcgtgga atgaattagt tagtttttcc gaaaaaattt
    22861 atgatattac gcaagaagat gagtgtgttt catgggaaat gaataatcaa tacaagaaaa
    22921 ttgacgcttt cgtcaaatca cgtatagaag gaacagcttt tgagtttgaa ggtatagata
    22981 ccgcagataa ttggttaaat aaagaatcct ttattaaaag tatagcggat gatcttgaaa
    23041 aacaatggtc taaggaagac tatgcagagt acctaaaaac agaaagagat acagaagtga
    23101 aagaaaaact cactgaggta tgtttggatg aacatattga tcccaatatc gtaaaacaag
    23161 aagactatga agtggttatt gataaagttc ctactgattt tgaggaagtt gtaaagtata
    23221 tagttgaaga agcattatcg caatactctt cagatgagga agtggacgaa gaaactgttc
    23281 gtaccagagt ttggcaactg gtttttgatg acaaagatta taaatatttg agtgatcaaa
    23341 actcggttaa ttggagtgta cgattattaa ttgatcaaaa tgatattgaa tagagctgaa
    23401 aagctctatt cagattgtag acaaaaagga gttggtaatt aagccactcc tttttgttag
    23461 tctttgcata attttgaaat aaaaagccat aggctttttt gttttccata gccatgtggc
    23521 tagttttttt aaattcatgg cagcaaacgt aagcatcgtg tgcgtggcga ctttttcaag
    23581 acctcgatat ttcgtccaac gcataccatg cttttctttt gcatctgcaa atattcgttc
    23641 aatggtttgt tttctctttt tgtaaatttc tctattcaac gccgtatggc gttggtgttc
    23701 aagttcatcc ataagatcag cccaaatatg tcgagtcact attttttgat gttttgtact
    23761 caaagtacaa ttttcaagta atggacaact cacacagaat tttggatttg atttataggt
    23821 tcgataacca tcacgagtga tagttgaaaa taacaacggt tgattattgg gacataaata
    23881 gcagtcaaaa taggcatcat aaacaaagtc ttttttacga aacattcctt tcactccatg
    23941 aggtgcagta tatggaagaa tcgggtagag tttcaagtgt gacagaaaat gaacaaattt
    24001 aggcgtctta tatcctgcat cagcaaccac acgctttata tttggaaaag ctcttttcga
    24061 ctgtttaacc agatcgattg cgacttggct gtcatgcaca tttcctggtg tgattaatgt
    24121 agataagata aaaccgttat cttcacagga agtatgtgca gaataagcaa attgtttttc
    24181 tcgttcacct ttaacatagt aaccactttc tggatctgaa tgacttattt tttgaagact
    24241 caactcactt tctgtgtccc atgtaaaagg acgttttcct acagcaatac gttctttatt
    24301 tatttcatct tctaattcat cttgataagc ttttgcttga ccgtaggtca tctctttcgt
    24361 gaacttatgt ttattggcat ttgctttgat atgagtagaa tcaatataaa ggttgtcttc
    24421 cgtaacgaag ccagctttta cagcttgttc tagaatatga gagaaaatat cttcaaataa
    24481 agttgtttct ctaaatcttc gaacatagtt tttaccaaaa gtagagaagt gtgggatagg
    24541 atcctcgaat gaataaccta aaaaccaacg gtaagcaaca tttgtttcaa cgtctttaat
    24601 tgtctgtctc atcgaacgga taccaaataa atattggata aatactaatt taattaagac
    24661 cactggatca atactgggac gaccataggt tgaatacgta gattctacaa tgggataaat
    24721 gaaatcaaac tgaatcgcag catcaatttt tcgaactaag tgatctttag gtacaagatc
    24781 atcaattgtt aacatagcaa attgatttct accttcaatc gattgttttc tcatcattag
    24841 aatcactccc agaatagttt atacaattag tataaaacaa aaaactgcaa acaacactcc
    24901 aaatttagga gtttgtctac agtctgaata gagctgaaaa gctctatttt ttttgataaa
    24961 aaaactagct attttattaa aaataatttg gttcaaaatt tattttttta acttgataat
    25021 tttttgccat ccttttttaa attggctata tatcaaggtt tatagtggga ataaataaaa
    25081 atacatttga caaaatttac aatatagttt attatatatt tatcttatta tgataacaca
    25141 ataaaaggaa tggtggtatg aaaaagaaga agtttagccg atcgttgtta ggaattttgg
    25201 ttttagttgc ggttggtctt agtggcaagg gttactttca gaataacagt actcaggaac
    25261 atgattttca gatcaaaagt agtgttcagg taggtaataa agcagacagt gaatcaaaag
    25321 aatttttagg gatacgttat gatccaaaca aatatccaaa taatatcgta aacattaatg
    25381 atgggaaata tacactgaca aaagaagacc atgaagcatt atcagaaaaa ggcagtcaaa
    25441 ccttttgggt aaattatgca gatttagatc aacttggaag agcaggagat gttgaagcgt
    25501 tgatcaccta tgatgctgta aattctcact catctaaaaa tgtggaacgt ccatctttca
    25561 aaagttctgt ccatattgca ggagaataca aggatggagt atttgatcaa gagagagata
    25621 cttgggtcgg caaagattca aacaatgaaa tcactcagct agaaggctat aaaggttatc
    25681 tctataacaa aagtcattca ttagcatggt cgctaggagg agatatggag gtacacaatt
    25741 taacacttgg aacgagagcg caaaatgttg ggaaaaatga tcagaatgga gggatggctt
    25801 actcagaaac gattgtacgt gatgcaatct ataaaaataa gaatgaaaaa gtattgtata
    25861 aagttgatcc aatttataaa gggaatgaat tagttcctcg tggttctcat gtcgaagctt
    25921 tctcagttaa cgataatgga aaaacggtaa accttaatgt ttatgtattt aacaatcaaa
    25981 aaggaatcaa catcaactat caaaatggta cttgggtaag agattagaaa ttgagaaggt
    26041 gaagaattgg aaacaataag catcaatgga ttagataaat cagttgcaaa tcgaataaaa
    26101 aaaggaaatg gctactatct tctgaagaag ggtaaatatt cagttgctag agagttagaa
    26161 acaatgagta tcgtgtatgt agctaagaat cattttgacg tagaacaggc tatttttgat
    26221 ccagattctg aaatagggaa atgtgttgaa ttatcagaga aaactgttag tacaaaaggg
    26281 gcgatgatca ttgagagaga aatgttagac gaaatcagag taatcattcc taaagatacg
    26341 cagatgtgtg aggacagcat aagtgacgat gaaccaaaat cagaaagaaa ataaggagat
    26401 attcagatga gcgaaaaatc cattgaatta aaggaatata agcgaagcga tggagaaaaa
    26461 tattatcctg tagccagttt ttctaaatca gtatatctgg ttggacgtgc attggtagtt
    26521 ggtgcaattg gcatatatat tttgcattgg gtaacaaagg ttgtacaact gcttgtagat
    26581 accttagtaa gtattcttgt ctcgttaaat gatgttaacg gaacagatga tttaggatta
    26641 aaagagatgt ttaaagagtt actcaatgcg ttttttccca attatttaag ttattcatat
    26701 aatgtacaaa gcttttttgc aaagctacac ttggtagaca tctctatttt agtattagaa
    26761 gcaggaacgg tattctttgt tggatatttg gttactttga tgttcaggca tcactatgga
    26821 gaacaaagac cattttttga tgatatggaa agtagaaggt tgaaaagaga agctctagaa
    26881 gctatggatg tgaagtatga tccaaacaag attataggag atgaaacgaa caacaaaaaa
    26941 agaaaacgaa acaaaacgca attagaatcc gatgtgctat caacgcttaa aaatatcaaa
    27001 atttctgttc atacaagacg tgatctaagt gtcaatgaag atattcgaga atatatcgta
    27061 aaaatcccgc aaccaaaagg gaagaaagtt agagaaacag ttttacgaca aattcaagat
    27121 ttagggtcga tcctgacaag agcaacaagc ggacgagcca aatttggtga aaaagaagat
    27181 gaagtttcag gcgattattt cattttccga gcatcagtaa atattgaaag agaacgtaag
    27241 gaaagagtaa gtaccaaaaa caaagaaacg gaaagagcaa catcttcaat cgcagtttca
    27301 aattcacaat tttcttttcc aatcaatctc tttgccgata attccaaaaa tatccaaaac
    27361 caaaccgaaa aagctagaaa atatgccgaa actcaaaagc aatctttaga actttatcta
    27421 tcttctgctg acgtacctgc aagtctaaca gatatgcacg ttgggaatac atctattgaa
    27481 tatttgttta ctttatctcg taccagaaaa attcaactaa gctcaatgaa agaagaaatt
    27541 gaaacttact tgcatatatc aggtgtaatc gtgcggatca acgcagggcg tattcaaatt
    27601 actttaccat taggagaaaa tgatcgtatt ccaattgatg taccatcaat gatcaatagc
    27661 gtgttttaga agacatcaca aatagaaaca gaaaatacaa actaccagtt cacaaacaga
    27721 aaagtaccga gaaaagtgag gaatagaaat ggctatgaaa ttattagaga aagtcaaaaa
    27781 gagagccgaa aaagctgaat ctattttgct agataaagaa actaatataa agcttaatgg
    27841 aaaattcagt gtcaatatgt tgaacacaaa ggctaaagac ccaacagatg ctatttttgg
    27901 aattaagcct gatggcacaa ttgctcattt ttgcatcagc gaaatgccac acatgttggt
    27961 tgcaggaacg acaggatcag ggaaatcagt attactgaat gaaattcttg ttacagtaat
    28021 gtgtcactca acgcctgatg aattaaaaat aggaattgta gacccaaaaa gggttgaatt
    28081 tggaagatac aaaaaattgc cgttcatgtt ggctgatcca attacagata tggatgaagc
    28141 ttatgatttt tttgaatatc ttgtgatctt gatgcatgaa cgttacaaac tgatggaaaa
    28201 agcagggtta caaaacatca cgctatataa cgaatatgcc gaaaaaaatg gattagatag
    28261 atttccctat gtgatcttat tagttgatga atattcacag ttggttggaa cacataaaga
    28321 agtagaaggt ttgattgttc aattaggaca aatggcaagg gcagcaggta ttcatgttat
    28381 cttagcaaca caatctcctc gatcaacagt tgtcactggt attatcaaag ccaattttcc
    28441 gtcacgtgtt tgccttatgg tagcaagtga tttagaaagt aggattgtat tagatgaagg
    28501 cggtggagaa agtctaagtc caaagggaga tatgcttatt aagcttgttg atggaagtat
    28561 ggttagagcg cagggagctt acatcagtaa caaagaaatt gaaacaatct tcaatcacct
    28621 tagaaatact atgccagaac cagaatatgt tgattaccga gcaatcgtag ctgaaactcg
    28681 tggtgagggc ggtgaagacg aggattttgg tggaattggt aaagctcctg taagaaaatc
    28741 tgctaaaaga aatttgaaca cacctttagc aaatccatca tctaaagagc catcaattga
    28801 aaagaagagt gcgtttgcta ttaagcttga aaagaacaaa gaagaaaaag tcgagcaggg
    28861 agctaaaaca ctagaaaaac tgcaagcaga aaaactagaa aaagttttaa gggcattagg
    28921 aaaagctgat cctgaaccgc aaacctcaaa caacacgaat aataaacagc cgattgcatc
    28981 taaaaccaaa cctaaagcta atgatccaaa aggctcagaa aacgtagtga tcacaactga
    29041 taaatctgaa aagaaacaaa taaatggaag tacttcacct atcatgcaaa aaatgttaaa
    29101 agcaaaaaaa caggtgcata aatgatcatc gtcagttctt ttttaagatg gcttactcca
    29161 tataaatata cagatgaagt agttgtgaaa cgagcgaaga aaagagataa aaaagcggta
    29221 ctaactccta aacagatgct tgatcatggc attttagggg tgaaggtttt agaagtgaat
    29281 aaaccgtttg aatcaaatag tgcaagagaa aagttgcttg gagctgaagc cgatgtcgca
    29341 tatttttacc atgacaaaag caagcatcaa atagctatta aattcaatcc aaaatcggca
    29401 tggcggtatc aagcaagaga tgacttgaaa cgtaggaaac ttagaccaat gctctatcca
    29461 gaaggaaaag aagcatttga tagaacccac atcgttccca ttggttttca tggtacagaa
    29521 tcagataacc gcctattagt aggttggaac agcaatcaaa atagagttca gatcaataaa
    29581 tttgagaaga aagtaaggaa attcaacgat cgaaaaacga tcctatggtt tgcagatatt
    29641 tgtaaacagc cggatggaac agcaaagtgg gaagcggtga tatttgacga aaatggtaaa
    29701 aaagtaatgt ctgaaacatg gcatgataaa gctaaatttg tttggcagta gcagtagagg
    29761 tgaaaaagat tgctagaact ttttgaagca aatagaacag gctttaatca aaagttagaa
    29821 gtgggagaaa ctatagaata taaagataaa aactatatta ttatcggaat ctataacacg
    29881 agaattaaca gaataggtga tccacgtata accagtgact tggtttgtca atctgttaac
    29941 tattcacctg atctgacaag caggtataag aaatacgtgt tattagaata tagacacaag
    30001 attactgatg aaattggtgt aaacaacaca cgaaacatat ttaagatcgg aacagtgatt
    30061 ccttatagta acaacgaaga aaaaatattt tatcagattt acggaataga aaagtttgaa
    30121 tatgaacatg tcgatctgct agtgacgtac caaatgcgtt taatagaacc ttggtcacag
    30181 gcagaaattg ataaagcagt aaaattgaac cgattatcaa aatttaacgt attaggaaat
    30241 gccttttaaa aatcgcaata cacaaacaga aaaataccaa aaaattagca atgaacgtag
    30301 gtaagaacat gacaataaat aataataacc ctaaaaaata taatgctctt gtccaatgct
    30361 atatcgaaaa caaaattaca atgcaagaag tcgctgatga attaggcaaa tcaaagagcc
    30421 tagtatcaca cgattttaag cacaatgttt ttccgaaccc gattgagctg aggaaaaaat
    30481 ttcaaaagag agtttatcaa gaaataggta agtggattga tgaagggaat gcaattgacc
    30541 ctttaattga aaaatatcct tttttaaaaa gcaaaaataa aattcaaagg ttaattcgtc
    30601 aaggcgatat tcaagctaaa gaacctgttt tgacaaccaa tgatttggct aaaataaatc
    30661 ttcataaaca aattattgaa gactttgaaa aaaatctttc aacaactgaa attttaaaaa
    30721 aatacaatat tccgagagga aagctaacat cgactctttt tagagaatat ggagaatcgg
    30781 cagttactaa agcaaaggaa gtagcgaatg agagaaaaaa acaaaaatag tagtcgatac
    30841 ctagtagcga ctgtagtttt tgtttgtgta ttgattttcc tgtttgattt tttgcagatt
    30901 ggaaaaagca taattggaaa tacattgagt gcaaaggaaa tggttgcttt aggtggtttg
    30961 tatgaaggac acttgttccc gaatatattc atttctatcg tttctcatat taacttgtac
    31021 catttaattt ctaatttatt gttcttagta gttcttgaag aagcactgaa tgatcagtat
    31081 gagtggttaa cattattgat cgttttaatc atatcaggat ttctaggaag cttagttcct
    31141 tttctgctac acagcaacat cgtaagtatg gggcttagtg gaggtatttt tggatggatt
    31201 gctttatttg cgattgcata catccgtttt gatagcaaga aacatttatt actaagtgtt
    31261 tttgtattat tgataatcgg cattttattg gtatctactt ttgaatcagg cgaggcaaat
    31321 gtcttgtcac atgtaatcgg atttgtctgt ggaatgatct tgggatttat tctaaagaac
    31381 gtttcattga tcaaacaaaa gaattaaaag ggagtgctaa aaatgccaaa aagaaaagaa
    31441 aagaaaattc cagtgttttt gtctgtctca gaaatgttat cacttcaaat actgttaaga
    31501 aaaaagattg aaacaataga cgaagaagtt agaaataaaa gggctatgta cgaacaacgt
    31561 gaagcgctaa gagaacgaat ccactatttt gatgatatac acactaaaat ctatgaagca
    31621 cgtacaaatc acgaagacga aagtaaatta ggattagctc aacaacggat acttgaatgg
    31681 cttaatacga atactgatca agaaccgtta agagtgatta gtaatctttt tgaatttgga
    31741 acgaagcatt ggtttaatgc tgtagagaag gatgctgact tacaagaagc gtttgatacg
    31801 ctaagtaagg atagcaaatc catgcgagat ttattgatta cttatctaaa tgagcatgag
    31861 tttgaacaaa cgaaaaccaa aaagaaaaat aaagaataga aagttgtgat gaatcatgct
    31921 attaaccctg ttaggttatt tatgtttaat tcttgctttt tttggggcaa tcgctataat
    31981 tattggtcaa tttcaaacaa ataatccgat tatgcgtaac ataggcattg gaattgtgat
    32041 tgtaaccttt attgtgttta atgccactaa gatttttgga agtaacgata aacaatttgg
    32101 tatatcggga gttaataata gttatgctcc agattctttg ggaagggtag taatagatgg
    32161 aacatttgaa aatgtaacga gttataaaaa tgtttcgctg acagtgaagg aagatggcaa
    32221 gaaagcatca gacgacgttc tcgctactat taagccgtct caatcacaat ttgaagtgtt
    32281 ttatacagtt aaagagaata gccctgtaca caagctgaca ttggttttta acgttgatgg
    32341 agaagaatac tataaagatg taaaaataaa taaaacatca acgaaaaaga ttatcgaatc
    32401 agcgaaaaaa gaagtagcta cagaagaaag tacaactgaa tcaagttcta ctgtcgaagc
    32461 ggaactacca gataaaattg attttgatcc tgaaaaagtc aaatcgtttg aatctgtttc
    32521 tggttctatg gctgatcggt ttaacactga agtcttcaaa gctatcaaaa ctgttaaatt
    32581 ggatactgaa aagcaaatga ttaatgttac cttattcaat tcagttgaat ctatggatca
    32641 ggataaaaaa gttacggttg caagagaact aggaaaaaga gtaattggtt tgtatcgtgg
    32701 tactgctaaa ccagattcag acggtgcaga tttgccagtt catgtagttt atgaagacgg
    32761 taaagttttt ggagattcta cagcaaacga agcattaacg attaaattgg ctaaatagcc
    32821 agaaagttat aataaacaaa tggtgtcaca ccaataatat ataggtgtga caccttggag
    32881 atgatagctg atggtagtaa ataaagaaaa agttagaaag tatgtgactt taaaaatagc
    32941 ttctgttaaa tatttagaaa agcgagctaa agaagaagaa agagcaagag gtaagaaagt
    33001 aacagtttca gagttgttag aagaattgat cgagaatgat caaacaataa gacgtgcatt
    33061 tactaatagg tctatcagat aacaatataa ttaataaaaa agaaagagtg atttggtctt
    33121 agactaaatc actcttttta tataaagttt ctttacactc attccgaata atgttaaaat
    33181 tctttatatg atatatagtt ccttgtcaga ggaagagata accagcaata ttggagggat
    33241 aataagtgga aaacaataat gatattagac attttagcat tggggaaaga gttacaacag
    33301 taagtgaatt atcaaaggat tatagagata aagagggaac gattatttct cttaataaga
    33361 atcgaagagg cgtttggcaa tatgttgttg atttaggtga tggcgttaca gttgagtgta
    33421 aagatagtca actgatcaga aataatggca gtcattccat tgaaaaagca attcttgtat
    33481 acccaaaagt atcaagtaag atcatgaatg actggttgct tggaaaattt ggtgagtaca
    33541 ataaaaaaga aatcgcagaa gtgatcggca aatcttatcc aacagtatta gggtatctaa
    33601 aaaagataac gagtaaagaa gcaaaaattg aggatgtttt aacagtaaga gagcttcaat
    33661 cattaatcga gtatcggaat aaacaaataa caaatcctga gtaccttaga aaagaagatg
    33721 gtctattgaa acaattggaa caagtaaata aaatccggaa gatgcaaaag gtagctcctt
    33781 taagccttga tacctttaaa aaaatctatt tgaaagagat caaaaaagac taatgtggac
    33841 tgtaacttta ccgttccaac ctgtatctgc accaagacca agtgcaagaa ggaatgctgc
    33901 tgatgaaact aatgacgtag cagagaaaag gatttcaacc tactatgata aaaagtatct
    33961 tgattatttg aaaaaaataa agagctttat cgaagatcaa gatttattag atgatgaatt
    34021 ttactcgatt gtaaatgatc ctatgggcgc aattatggaa gtggactttt actaccagat
    34081 accaaaaagc tataaaaaag tctataacat tatgaagaca acagcgccag atttagataa
    34141 tttagtaaaa agtgctatgg atggtatttt taacatctca gctatacgag atagccatat
    34201 cacaggctta attgctttta aatataatgt ggcgaacgaa ggaaaaacag ttgtgaggat
    34261 caaacgatat tcagaatttg agtgggatac ttctgaagga ttgaacggag atatatggga
    34321 agctacattt gattttaaac cagtagcaac gccaagacca aagtctaaat ttagaggaaa
    34381 tgggattatc acttactatc caaaagagta caacgactat ttggaaaata tcaagaatac
    34441 gcttaaagag aaagatttgg taaatgatca actgaaaaag gtaatgaatg ctcctatggg
    34501 ggttatagct cagatagatt atttttacca agtgagaaaa gataagaaaa agcttgattc
    34561 actgatgcgt acttcacagc cggatattga taatttagtc aaaggaacat tggacggaat
    34621 ttttaacaag gaaataggca tcaaagatag cagggttgta gggttaattg cttttaaata
    34681 caatactttt gaaaagtcga aaacaaacgt gagactacag gagatgggct gatgaataat
    34741 aatgaaaaaa ttcttcatgt acttgatagc tttgaaataa ttcaagaaga actaaaaaaa
    34801 tatcgggatg ttttggaaca aagatatgat tttgtcaatc agcaaaagag taatcacatg
    34861 gatttcattc tcaatatgaa tgacttgaag aagaaattag ttgaacgaaa agaacaagaa
    34921 aagttgatca aagcttactt tgaactcggt gaaaaagaag ttaaaaatgc aatggaactg
    34981 aatgaagagc gcagggtttt agatcagctg ttagaacaat tattggtgat gtttcaaaaa
    35041 ggacgaatag atgaggattt aattgaagaa ggattgagaa aatatccttc aaactcaggt
    35101 atcggaatag tgctgaaagc gattgatgaa gaagaaattg aagctttcat accgccagag
    35161 gattttgaat cggcaatgga atatataaaa tattatagcc aagggatcac tgcttttaga
    35221 gagtttgatc ctgaagatgt tattcatgac ttgaacaacc taaaagaatg gtgtgaaagt
    35281 tatggagtcg atgattccgg attggactac ttgatcagta ttatggaaat cgaagaagag
    35341 atgccggata agcctgatcc aacagatatt ttagaattga tccatgaagc tagaaatcca
    35401 attgcctata tttctagagg atatactgta ttggaatact ataagcctta tatatcagcg
    35461 atgaaccatt taagacgtgt attaagggaa aaacgtgaat accgctcagt gttgaatgca
    35521 acgaatagat tagaaaaagc tgtttcagag ctagatgctt attatcgtga acattacctg
    35581 caagcaggtg gtatgccaag aaatacgaaa gcaaatatca gtaggtatat aaaaaaagct
    35641 gagtaggcgg agttagccca taaaatggca aaaggtaacc tgaaaggggc attttgaatg
    35701 aaaagggatg tttttgaatt gtacgtatta gaacgtctag aagacggcat gatggcacaa
    35761 gagataattg atgaaattga tgatatgatc agcagatttg gtcaattgga gttgaatgat
    35821 ggaaacaaaa attcggtagt gctaaaacaa ttttggttga acaatttttc gtataaggat
    35881 tttatcaaag aaaaggcaaa tacattgtac tgactaaatt cacgaggagc agtgatgaga
    35941 gcttattgct aagagcagtt aggctctttt ttgtttgtgt aaaattattt gttttataat
    36001 acacatttat acacaaaaaa atattgacag atagtacaca aatgtggtag gatatatttg
    36061 taagcaagtt agattaacaa gttaaaggaa gagcagttat gaaaaaagaa gaactaatag
    36121 atatatttca aattgttgaa cgagcaaata atatgggaat tatgtttttt gatcgtattt
    36181 ctttaaagat gg
//
LOCUS       DADGKS010000021        34957 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.021, whole genome shotgun sequence.
ACCESSION   DADGKS010000021 DADGKS010000000
VERSION     DADGKS010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34957
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.021"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            153..1859
                     /locus_tag="JXV47_001177"
     CDS             153..1859
                     /locus_tag="JXV47_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin/fibrinogen-binding protein"
                     /protein_id="HAX1487231.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2017..2919)
                     /locus_tag="JXV47_001178"
     CDS             complement(2017..2919)
                     /locus_tag="JXV47_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAX1487232.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2916..3620)
                     /locus_tag="JXV47_001179"
     CDS             complement(2916..3620)
                     /locus_tag="JXV47_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HAX1487233.1"
                     /translation="MKKNMDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKG
                     EETKIEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSE
                     HIINGKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVN
                     PDVFFPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPI
                     QPLNGREIYYFEEFEQ"
     gene            complement(3651..4292)
                     /locus_tag="JXV47_001180"
     CDS             complement(3651..4292)
                     /locus_tag="JXV47_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAX1487234.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4330..4644)
                     /locus_tag="JXV47_001181"
     CDS             complement(4330..4644)
                     /locus_tag="JXV47_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487235.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4632..5261)
                     /locus_tag="JXV47_001182"
     CDS             complement(4632..5261)
                     /locus_tag="JXV47_001182"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HAX1487236.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            complement(5268..5984)
                     /gene="pyrF"
                     /locus_tag="JXV47_001183"
     CDS             complement(5268..5984)
                     /gene="pyrF"
                     /locus_tag="JXV47_001183"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HAX1487237.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            complement(5981..6913)
                     /locus_tag="JXV47_001184"
     CDS             complement(5981..6913)
                     /locus_tag="JXV47_001184"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HAX1487238.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6910..7686)
                     /locus_tag="JXV47_001185"
     CDS             complement(6910..7686)
                     /locus_tag="JXV47_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HAX1487239.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7740..10925)
                     /gene="carB"
                     /locus_tag="JXV47_001186"
     CDS             complement(7740..10925)
                     /gene="carB"
                     /locus_tag="JXV47_001186"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HAX1487240.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10930..12006)
                     /gene="carA"
                     /locus_tag="JXV47_001187"
     CDS             complement(10930..12006)
                     /gene="carA"
                     /locus_tag="JXV47_001187"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010744830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HAX1487241.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12011..13291)
                     /locus_tag="JXV47_001188"
     CDS             complement(12011..13291)
                     /locus_tag="JXV47_001188"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HAX1487242.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13310..14236)
                     /locus_tag="JXV47_001189"
     CDS             complement(13310..14236)
                     /locus_tag="JXV47_001189"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HAX1487243.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14249..15532)
                     /locus_tag="JXV47_001190"
     CDS             complement(14249..15532)
                     /locus_tag="JXV47_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HAX1487244.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15546..16085)
                     /gene="pyrR"
                     /locus_tag="JXV47_001191"
     CDS             complement(15546..16085)
                     /gene="pyrR"
                     /locus_tag="JXV47_001191"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015694870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HAX1487245.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16320..17231)
                     /locus_tag="JXV47_001192"
     CDS             complement(16320..17231)
                     /locus_tag="JXV47_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAX1487246.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17228..17692)
                     /locus_tag="JXV47_001193"
     CDS             complement(17228..17692)
                     /locus_tag="JXV47_001193"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HAX1487247.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17697..18395)
                     /locus_tag="JXV47_001194"
     CDS             complement(17697..18395)
                     /locus_tag="JXV47_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAX1487248.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18382..18768)
                     /locus_tag="JXV47_001195"
     CDS             complement(18382..18768)
                     /locus_tag="JXV47_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487249.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18915..20585)
                     /locus_tag="JXV47_001196"
     CDS             complement(18915..20585)
                     /locus_tag="JXV47_001196"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HAX1487250.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20768..21001
                     /locus_tag="JXV47_001197"
     CDS             20768..21001
                     /locus_tag="JXV47_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HAX1487251.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21100..21531)
                     /locus_tag="JXV47_001198"
     CDS             complement(21100..21531)
                     /locus_tag="JXV47_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HAX1487252.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21610..22023
                     /locus_tag="JXV47_001199"
     CDS             21610..22023
                     /locus_tag="JXV47_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HAX1487253.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            complement(22061..23209)
                     /locus_tag="JXV47_001200"
     CDS             complement(22061..23209)
                     /locus_tag="JXV47_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAX1487254.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(23331..23927)
                     /locus_tag="JXV47_001201"
     CDS             complement(23331..23927)
                     /locus_tag="JXV47_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAX1487255.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(24127..26769)
                     /gene="alaS"
                     /locus_tag="JXV47_001202"
     CDS             complement(24127..26769)
                     /gene="alaS"
                     /locus_tag="JXV47_001202"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HAX1487256.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            27157..27588
                     /locus_tag="JXV47_001203"
     CDS             27157..27588
                     /locus_tag="JXV47_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1487257.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(27633..28982)
                     /locus_tag="JXV47_001204"
     CDS             complement(27633..28982)
                     /locus_tag="JXV47_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAX1487258.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(29052..30215)
                     /locus_tag="JXV47_001205"
     CDS             complement(29052..30215)
                     /locus_tag="JXV47_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487259.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            30344..30667
                     /locus_tag="JXV47_001206"
     CDS             30344..30667
                     /locus_tag="JXV47_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487260.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(30850..32199)
                     /locus_tag="JXV47_001207"
     CDS             complement(30850..32199)
                     /locus_tag="JXV47_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAX1487261.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(32268..33221)
                     /locus_tag="JXV47_001208"
     CDS             complement(32268..33221)
                     /locus_tag="JXV47_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HAX1487262.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(33323..34513)
                     /locus_tag="JXV47_001209"
     CDS             complement(33323..34513)
                     /locus_tag="JXV47_001209"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HAX1487263.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
BASE COUNT         9950 a         7640 c         6120 g        11247 t
ORIGIN      
        1 taaaaatttg gatttcaacg atagaaacac tgttttttat gtaattagtc caagattttt
       61 ctagactttt gctttactat tcggccaaat tggtttttct tctttttttc gttataatga
      121 atatacttat gaaaagaaat gaggaatgaa ccatgtcctt tgatggtgta tttacccacg
      181 cgatggtcaa cgaattgcgt gaaacgttac tatctggccg gatctcgaaa atccatcagc
      241 cttatgaaaa tgaaatcgtg ctggtgattc gttcacgcgg caaaaaccat cgattattat
      301 tatctgcgca cccaagttat gctcgtgtac agattaccca aatcgattat cagaatcctg
      361 ataatccgcc taacttcgtg atgatgcttc gaaaatattt ggatggcgct attttagaag
      421 acatcgaaca aatcgaaaat gatcgagtga tccatttcca ctttgctaaa cgaaacgagt
      481 tgggtgatct acaaaatatc atattgatcg ttgaattaat gggacgtcat agtacgatcg
      541 tcttagttaa tcgagaaact ggaaaaatac tggatgcgat caaacacatt ggaagctctc
      601 aaaacactta tcgttctttg cttcctggtg tagaatatgt tgctccgcca aaacaagagg
      661 tcttgaaccc atttagctcc gagaaagaaa aaatctttca gcggctttcc caaactgaac
      721 tagatccaaa agcaatccaa cgtcagtttc agggaatcgg tttcgatatc gctcaagagc
      781 tgaccaaaag attactggaa cgtcctaatg aaaagatggt tgtatgggac gaatttttct
      841 cagccatcag ccatcagcct attcctactt tttacgaaac ggaaaataaa gattttttca
      901 caccgattgc ttatcaggta ttgtccgaac aggcatctgc tgtaacagct tatccaacac
      961 tcagtcaatt attagatagc tattatcacg aaaaagcaga gaaagatcgg gcaaaacaac
     1021 aaggcggaga actgattcga aaaatcgaaa atgaactaaa acgaaataaa aataaattga
     1081 aaaaacgtga acaaacactc aaagaatccg aaaacgctga gaattaccgt agaaatggcg
     1141 aactacttac tacttttctg acacaagtac cacgcggcgc aaaagaagtt gttttaccta
     1201 attattatga agaagatcgg ccaatcaaaa tagcactaga tccggcattg acaccaaatc
     1261 aaaatgcaca gaaatatttc catcgatacc aaaagctgaa gaacgctgtt aagctgattg
     1321 gcgaacaaat ccaagaagcc aaagatgaaa tccaatatct tgaatctgtc ttatctcaac
     1381 tggaaattgc cggcccaatg gatatcgaag caattaaaga agaattgact tcagaaggat
     1441 acctgaaaaa gaagaactta aaaaaacaaa aacgtaagaa accatctcag cctgatcaat
     1501 acttttcttc tgacggaacg ctcattcttg ttggtaaaaa caatcttcaa aatgaccagc
     1561 tgacaatgaa gacagctaaa aaaaccgact attggcttca tgcaaaaaat atacccggtt
     1621 cgcacgtcat cattaaaagt gacaagccct cagatgaaac aattacagaa gctgccgagt
     1681 tagctgccta tttttcaaaa taccgatact ctgcccaagt gccggttgat cttgtacagg
     1741 taaagcatat ccgaaaacca aatggcgcca agcctggtta tgttatttat gaaaaccaaa
     1801 agacgattat cgtgacacca gaagaagaaa aaattacagc tatgaaacaa aacaggtaat
     1861 caatgagtgt ttctagaatc atatttgcgt actttcccac aacagcaatt agttataaat
     1921 tgtttgctac aaaaagagga gttgtgacaa aattctgtca caacccctct tttttgatca
     1981 acggtgttca ataaacagcg ttctcatctg cttttcttag ctctgctggt ccagtaaccg
     2041 agtaagctct ttgataaatc tttgagcgat ttcactgagc ggacgtttcg ccgaataaat
     2101 gatataaaat tcatttagtt cgccttctgc caaagggatt aaccgcaagt gctcgcgaat
     2161 ccctccaatc acaataccag atcctgaagc gtaagcatca gtttcaagaa cgatattcat
     2221 caaagtacct cgatcactcg tataaatcac tgtttcttga tcagggatct cgataaggtc
     2281 ttcataaaaa tacgggaaat tatttccatc ctgtgtaaaa cgaacttgag gataagataa
     2341 caattcttct ttggtgatct ctgcgtgttc agctaatgga tgtccttgcc ttaaaaaaat
     2401 atgcgttttg aattttccaa tgctgcggcc acttagctct ccttgttgta aatatcttct
     2461 gataccagct tgattatgct cattcatata aataatgccg atctcactgt gctgctcttt
     2521 gacttcttcg atcactctcg ctgttgtcgt ctccatgatc cgaaattgtt tgatctcgtc
     2581 tttgaattcc tcgagtagct gtgcggtcaa aggacctaag aaatcataat gctgggcagc
     2641 gatcgaaaaa ttgtctctct tttcactcgt tagatagtga gtttctaatg tatcaagctg
     2701 gaccaatatt ttctcggcac gatttaagaa gtcttgccct tcttctgtta aatatgcccc
     2761 tcgattcgtt cgagtaaaca gcgtgatccc taactcggtt tctaattctt tgataccagc
     2821 tgaaagactt ggctgggaga caaacatttt ctttgccgct tctctgaaac taccattgtt
     2881 tgctacagcg accacgtatt tcatctgctg aatattcatt gctcaaactc ctcgaaataa
     2941 taaatttctc ttccattcaa gggctggatt ggtcggttgt tcggtcgagc atactgacca
     3001 tcgaagggga gaagaaactc ttggttcagt tttcctacat gatccattac aaaccattgg
     3061 attggcccgc tggtaggcgg agttgtcaat gagccaatat aatggaaatg gcttttttgc
     3121 tccggaaaga acacatccgg atttacccaa tgctcatgtt tttctaagtt ccaactttcc
     3181 ccattttctt gattatacag ccaaccttcc tgtaccatta gctggtacat gacacccaca
     3241 actagattct cttttttgct gttcatatga acaaaatgaa attcaatatc ttcctgtttt
     3301 ccgttgatga tatgttcaga aggcaagtgg aaatgaatat ctgtcaaata atagcgttct
     3361 ttcttgaact ctacataact gagttggtca aaaggtacta aatgaatcgt gtttttgaat
     3421 tccttgtcag taaaccgttg cttttgataa tgaaaggaaa gcgtgtctcc ttctattttg
     3481 gtttcttccc ccttggtcaa atgaataggc gactgcaatg gaaattccgc acctctcgca
     3541 aaccaatcac ataaactcgc ccaattttcc ggacctttgt ctccagaata gccccattcg
     3601 acatccatat tctttttcaa ctatacttcc ccctgcatct catatcattt ttatttttct
     3661 tctttcttta caatcgttga gacggtttct aaaaacgcct cttttccata aaattcctgg
     3721 ttcaatagtt ccggaaatat ctctttaaag aaatactgaa cagaaggccg atgttcaaag
     3781 cttttaatcg tagtcactgc ctcaatgaac atctccttat aaactttttc cgggttattt
     3841 ttgatgattt catcaaaaga ttcataaaga aggtcaacct tatctgaaat ggctaatagt
     3901 tctccttcta cggtttcatc ttttccttcg aacaaccgac ggcgataaac ttcttggaac
     3961 tcagctggaa tctcttggtt gatgaattcg tccgtcatct tttcttcaac tgtttgcagc
     4021 atccctctta actctttgct tgcgtatttc accggcgttt tgatatcacc aataaaacgc
     4081 tctgtgtagt catgattcaa tgatttttca tagagcagtt tccaatcgat cggttgtcca
     4141 ttcgcttctt caatgtctcc tagaacttgc gcaatagatg ctacacgata cgaatgtgct
     4201 gcaactgtat gctctgtata tttaaaaaat ccaggtgccc ttgtgatcgt ctctaaattg
     4261 ttcaatccta aaataaattc attcaacccc ataaaagtta cctccctttg agatttcttt
     4321 ttccgaatat catatcatta aataactgat attcgcaaca tttccgctct ttaccatttt
     4381 tgaaacagct cccttaccaa aaaatagaga aaatctatat ataatagaaa aaagagaaga
     4441 gattattctc ttctttctgc taaccagtct tagaaaaatg aattttaaaa aaatcaaaaa
     4501 ctgatcacga tagaagtttc ttttcatacc tgatgaaaag atgcttctcg caatcagttt
     4561 ttggattttt gctattccaa ttgatgattc tggagacaca aatcggattt ctctatcttc
     4621 atcaagcgcg cttaaatctg ccaattttca ggatcttttt tccattcttt tagcagagtt
     4681 aattcttgct catcgatata acgatcttct aaagctgctt caatcaatac agaataattg
     4741 gtcaacgtca taagagggat ttcggctttt tcgaaatttg cttttccttt tggcaactca
     4801 tacgtaaaga tagccgcaac accaaggata tccgcacctt ctctttttgc tgcttcagct
     4861 gcttccaaga cacttccgcc tgtagaaatc aaatcctcga tcacaaccat cttctgacct
     4921 tcaaatatac gtccttcgat ttggttacct ttcccatgat ctttcgcctt acttcgaata
     4981 tagaccattg gcaaatccag tatttccgct acccatgcgg catgagggat tcctgctgtt
     5041 gcagttccag caatcacttg tacttcaggg taagcttctt tgattttgct tgctaatcct
     5101 tttgcgatct cttttcggac ttttggatag ctcatcgtga ttcggttatc acagtaaatt
     5161 gggcttttga ttccacttgc ccatgtaaaa ggattacttg gatttaaaaa tactgcttca
     5221 atttctaata agtcttttgc gatactttgt tcaacattca ttttaggtta gctccattct
     5281 gtttgaatcg tttgatatgc tttataagga ttagttgact gagtgattgg tcgacctata
     5341 acgataaaag ttgagccgat cttttttgcc tgagaaggtg tgactactct tgtctgatct
     5401 cctgcgactg ttccttctgg tcttataccc ggagttaagc aaacaaattc gtctcctgcc
     5461 atttctttga tcgcttctac ttcccaagca gaagaaacca caccatctaa tcctgctttt
     5521 ttggcacagc tagcataatg gatcacactt ttttctaaag aaacttcgat tagttgatcg
     5581 gcatgcattt cttcttcact tgtagaagta agctgagtga tagctagaag tagcggacgt
     5641 tttccacctt ctggagtccc ctcttctaat cctcgcattg ccgcctccat catacgaata
     5701 ccgccagcgg catgaacaca ggtgagatca acaccaagct ttgccaatcc ccgcattgct
     5761 ttttcgaccg tattcggaat atcgtgaagt ttcagatcta aaaatacatt atgaccagcc
     5821 tcttttagat aacgtacgat ttcaggtcct tcttggtaga acaattccat tccgattttc
     5881 acaaacaatt tttcttcttt cgggaaaaat cgaagaaagt cttctacctc ttgcctagtt
     5941 gaaaaatcta atgcaataat tggtcgttgg tctagttgat tcatcgttca cgttcctctc
     6001 tcacttcttt gattaatctt tccagcgatt cgatgcctag ttcgctcatt cgcacaggga
     6061 gctctttaat tagtttagga cagatatacg gatcggtgaa attcgcggtc cctatagcta
     6121 cagcacttgc tccagccata aacatctcaa gaacatcatc cactgtctgc acgccgccca
     6181 tcccaatgat tggaaggctg gatatacttg ctacttggtg aatcaaacga atagcgacag
     6241 gcttgattgc tggtccggag agtccacctg tttgattggc taaaatcggt tttcttgtct
     6301 taaggtcaat ccgcatacca agaagagtat tgatcatcgt aaacccatct gcccctccag
     6361 cttcgattgc ctgagcgatt ggaacgatgt ctgttacatt tggggacaat ttgacataga
     6421 caggaacaga agaaactttc tttactgctt gtgttaattg aaaagcaaca tcagaatctg
     6481 ttccaaaagc aattccgcca tgtttgacat ttgggcaaga aatgttcagc tcgattgctt
     6541 tcacatttgg tgcttcgcca attttgctac aaacttctac atagtcttct tcacaagcac
     6601 cagcaacatt tgcgatgatg ggtaactcat tgtactcctc taattctgga agaagtttat
     6661 gcataacaac gtctagacca ggattttgca aaccaattgc attcaacatg ccagatggtg
     6721 tttccgccac tcttggcgtg ggattgccaa agcgggcatt tggagtcgtt gccttgacca
     6781 tgatcgatcc aagctgattc aaatcatagt attttccgta ttctttgcca aaaccgaaac
     6841 agccgcttgc cggcatgata ggatttttta attctaggcc aggaagtttg accgctaaag
     6901 gattctcatt catataatta cctctcctat tttaaaaatc ggtccttcgt cacaaacttt
     6961 cacacttttt gttcctgttt catcttccgg cgtatgacaa acgcaagcat agcaagcccc
     7021 tatcccacat gccatgcggg attctaatga taactggaca ttttgatgcg aagaaaacag
     7081 ctgttccact gtcttcaata acccgtttga accacatgca aaaacagctg taggttccgt
     7141 cttcgttcct aacaataaat taccgacatt tccgtgcata ccgtatgttc catcgtcagt
     7201 agcgattctt gtttctccta gacgattaaa ttctttttca taataaacga cttcatgtgt
     7261 ggcaaaacct aaaaaatgcg ttggcttaat tcctttttcg actaactgtt ttgataactc
     7321 atatagagga gggacaccga ttcctccacc gattataaat acttcgtctc ctgtatgaag
     7381 attggacaaa tcaaaaccat tgcctaaagg acccatgaca tctaaatggt ctccggcaga
     7441 aagagtagag aagactctag tcccctcacc ttccacccga taaatgatac ggcaagtatt
     7501 tgtttcgtgg tcgatatgat tcaagctaat cggtcggcgt aatagcaagt ctgcacgcgg
     7561 cacgagaata tgcaagaact gtcctggttg ctgcatttct tttactagat cacctttcaa
     7621 tgtcatttca aaaatctttg gtgccagctg tttttgctga acgatttcca tcatttcttg
     7681 tttcatctgt cccctcctgc aacggttttt cgtctttttg tcttaacatg tgctcgccgt
     7741 taaatagggt tagttgaaaa agcacgggat tccatcactc gaacgatcgc atctgctgtg
     7801 tctaaagaag taaacaatgg aataccatgt tcaactgctt ctcttcggat gatgaaaccg
     7861 tctttagaag catttccccg atctttatca atcgtattga caaccacttg tgttttacca
     7921 tctcttatta agtcgactac atttttttct gctgcttcct cagaaatttt cgctactgtt
     7981 tcaacgacca gaccattttt ttcgaaataa gcagctgtat gtttcgttcc tatcagacta
     8041 tagccaattt ctgtaaaacg tttagctaat tctagtgctt cttcttttgt ttcgtccgca
     8101 atcgtaaata atacggctcc atattcaggc aagtgtaatc cagaagcttc gaatgccttg
     8161 tacaaagctt tgtctaattg tctgtcagat cccattactt ctccagtcga tttcatttca
     8221 ggccctaagt aagtatcaac tttctgcaat ttcgtaaaag aaaagacagg tgctttaaca
     8281 tgaacttctt ttgtttctgg ataaagtccg ttttcataac caagtgtctt tagtttctct
     8341 cccaaaatag ctttcgtcgc aatttgtgcc attggaattc ctgtcacctt acttaagaat
     8401 ggaacagtcc gacttgctcg aggattgact tcgatcacat aaacctcatt ttcatggatg
     8461 acaaactgga tattcatcat cccgacacaa ttcaaaccta atgctaagcg gatcgtgtaa
     8521 tcttcgatcg ttttcttgat cgattcagat aatgtttgag gtggatacac agccattgaa
     8581 tcccctgaat ggacaccagc acgctcaata tgctccatga tccctgggat gagtactgtt
     8641 tcaccgtcac aaatcgcatc cacttcgcat tcaccaccaa gcaagtaacg gtccactagt
     8701 actggatgtt ctggagatgc tttcacagca tgttccatgt aatcttctaa atctcgctgg
     8761 ttttcaacga tttccatcgc acgtccgcct aatacatagc ttggacgaac aagaactgga
     8821 taaccaattc tcgaagcgat aaccacggct tcttctttac ttgtagcagt atcccctaaa
     8881 ggttgaggaa tatccaactc tttcagcgct tgctcgaata aatcacgatt ttccgcacga
     8941 tccaagtctt cgatcgttgt ccctaagatt tttacaccag cagcagtcaa aggttcggct
     9001 aagttgattg ctgtctgacc accaaattga acgattactc ctatcggctg ttctagctcg
     9061 atcacattca tcacatcttc gaaggtcaat ggctcaaaat ataatttatc cgaaatagaa
     9121 aagtcagtcg aaactgtttc aggattgctg ttcatgatga ttgcttcgta tcctgcctgc
     9181 tggattgctt tgacagaatg cacagtcgca tagtcaaatt caaccccttg tccgatacgg
     9241 ataggaccag atcccagtac tagaattgag ggcttttctg atcgtgaact ttcattttca
     9301 tattcatagg aactataaaa ataaggtgtt tttgattcga attccgctgc acaagtgtca
     9361 accatcttat atacaggaat caaatcattt tcttttctca tctggcgaac ggcttcttcg
     9421 tttatttccc acagctccgc cacttttttg tctgtaaaac cgttttgttt cgctgttttc
     9481 aatatcttgt catccaacgg ctgctgtttc aactgctgtt cgatttctac gatatgcaac
     9541 agtttatcta aaaagaataa atcgattttt gtcaaatccg ctaattcttc tatggtgtac
     9601 cctcttctaa tagcttcagc tacataaaac aggcgatcat cttgtgctcg aaccactttt
     9661 tggattaggt catcgtccgt gatgtctgcc aactcaggaa gttcgatatg gtgtgtaccg
     9721 atttctaaag aacgcacagc tttcaataaa gactcttcga tattccgacc gatagccatc
     9781 acttcaccag ttgctttcat ctgcgtgcct aaaagccgtt ctccgttttc aaacttatca
     9841 aacggccagc gaggaatttt agctacaaca taatctaatg caggttcaaa ttctgcaaaa
     9901 gtcgttcctg taacaggatt tttcatttcg tctaatgtta atccaagcgc tattttagca
     9961 gctagcttag cgatcggata gccagtcgcc ttacttgcta acgcagatga acgagaaaca
    10021 cgcggattga cttcaatcac ataataatta aaactatgtg gatcaagagc gagttggaca
    10081 ttacagcctc cctcgatctt aagtgctcga ataatcgaaa gagaagcatc acgaagcatt
    10141 tgatattcat ggtcagacaa tgtttgacta ggggcaaata cgatagaatc acctgtatgg
    10201 atacccaccg ggtcaaaatt ttccatattg cagacaacga ttgcattatc agccgaatct
    10261 ctcatcactt catattcaat ttctttaaaa cctgcaatac ttcgttcaat caaacattgg
    10321 gtagcggggg aaagacttaa tccattttct gatacgatac gtaattcttc ttcattttca
    10381 cacatacctc caccagttcc gcctaaagta aaggctggac gaacgatgac aggatagccg
    10441 attttatttg caaaatctac agcttcttct actgtattga cgatttcaga ctcggggatt
    10501 ggctgattca attctttcat caactgtttg aatagatcac gatcttctgc ttgatcgatc
    10561 gcagaaagct ttgttcctag aagttctatg ttcaattctt ctaaaatacc tgatgctgcc
    10621 agctccattg ccatattgag gcctgtctgt ccgcctaaag ttggaaggag agcatctgga
    10681 cgctcttttc gaagaatcct tgatacaaat tcaagtgtga tcggttcgat atatacttga
    10741 tctgccactt ctttatccgt catgatcgtc gcaggattag aatttactaa aaccacttca
    10801 tatccttctt cttttaaggc aaggcaggct tgtgttcctg cgtagtcaaa ttctgcggct
    10861 tgaccaatga tgatcggacc agatccaatc accataattt tcttgatatc tgtacgtttc
    10921 ggcatctgtt tactgctcct ttcctgcgtc catcatttcc ataaattcat caaataaatg
    10981 tagtgcatca tgcggaccag gggcagcatc tggatgaaac tgcacactga aagcgggata
    11041 atctctgtgt ttgactcctt ctactgttcc gtcatttact tctacatgag ttacgatgag
    11101 tttttctgga tcaatcgtgg cttcatcgac tgcatagcca tgattttgag aagtaaaatc
    11161 aattcttccg gtcgctactt ctcgtaccgg gtgatttaat cctcgatgtc cgaatttcat
    11221 tttataggta tctgcaccgt tggctaaagc aaataactgg tgaccgagac aaataccaaa
    11281 aatcggtact tttccttgga tttttttgat catttcgatt gcttctggca catcttttgg
    11341 atcaccaggt ccattcgtca gcatgactcc gtctggtgat agcgctaaaa tcgtctcggc
    11401 atctgtgtta tagggaagta ctgtgaggtt acagtttctt ttactcaatt ctcgtaaaat
    11461 actatgtttc aagccgaagt caatgacaat gactttccga cctgttcctg gacttggata
    11521 aggtttgtta gttgagactt gctgcacttg attggttgct agaacggttg ctttcagctg
    11581 atcaaatgca tgttcgaagg aatctccagc atcaactata ctagctttca tcgttccgac
    11641 ttcacggatt ttgcgagtaa gggcgcgcgt atcgatacct gatattccag gaattccttt
    11701 ttgtttcaaa aatgaatcta gcgtcatttg gtttcgccag tttgaagcta cacgtgcatg
    11761 ttcttttact actactcctt tgcatgttgg agaaatcgat tcataatcat ctctatttac
    11821 cccataatta cccaccatag gataggtaaa tgtaatgatt tgaccgttaa aactttgatc
    11881 agtgatagtt tcttgataac cagtcatact tgttgtaaaa acgatttctc cgaagacact
    11941 agcatctgca ccaaaagcct ttccttcgaa aactgttcca tcttctaata taagcaaacg
    12001 ttccatactt ttattctccc ttctgccaca caagttttcc gttgacaaaa gtcatttgtg
    12061 tttcgccttt tactttccag ccgataaaag gtgtattctc cccttttgat aaaaagtctt
    12121 ctttatcgat cgtgcaagtt tgtgtaatat caaaaactgc tacatcagcg ggggcaccaa
    12181 ccgttagcgt tcctgcattc aaaccaaaaa tctcagccgg tttaactgcc aaccaattga
    12241 tcacttgttc caacgtgaat cgaccagttt ctacaaaatg agtatagatc agttgaaacg
    12301 ctgtttcgct tcctacgata ccaaatggtg atttcatgaa actttggctt ttttcttcta
    12361 atccatgggg ggcatggtct gtagcgatgc aatcgatcgt accgtcaagc aagccttcga
    12421 tcaaagcttc tctgtcctcc cgtcctctta gcggcgggtt cattttccaa aagccgaaat
    12481 cttcgggaat atcttcgtcg atcaaaataa gatgatgggg tgaaacttct gctgttacgt
    12541 ggattcctgc tttttttgcg tctctgatta cacggacact ttctttagta gaaacatggc
    12601 aaacatggta atgaacacca gttgcttcag ctagcaacag atctctagca atttgagaag
    12661 actcggttac gcttaagatc ccgggaagac caagttcttc tgccttcttg ccagcgtgca
    12721 taacgccgcc aaataataaa gattcatctt ctgtatgggc tactagggct ttattgtttt
    12781 ttgcagcttc tttcatagcc agatacatcg tcccagctgt ttggacacct acaccgtcat
    12841 ttgtgaaagc aaaagcacct tcttcaatca gtgcttcttg atcaactaat ttctcacttc
    12901 gcagattttc tgtgattggc gcatactgca ataccttcac aactgcatct tttctaatga
    12961 tgtcatatac ttgtctcagc ttttctgccg tatcaggtac aggatttaaa ttcggcatcg
    13021 cgcatacagt agtgaaaccg ccacgagcag ctgagcgagt cccagcttcg atcgtctcct
    13081 tgtatgtaaa tcctggctct ctcaaatgaa catggacgtc cactaaacca ggtgtgatca
    13141 attgtccctt tgcatcaaac acttcatcaa attcggcttc tgagaatcct gtaccgattg
    13201 ctttgattcg cccatcttct atccaaattt ctgctggtgt cgtcatattt tttcgtgtat
    13261 tgatctgacc gtttttaatg agtgttttca ttttttcatc ctcctataat tacgcttttc
    13321 catttagcac tgcttctaag attgccattc tgacgaatac tccattgctc atttgctgaa
    13381 cgatccgcga ctgtaatcct tccactaatg aatcagctaa ttctacatca cggttaactg
    13441 gtgctgggtg cataatgatt gcatgttttt gcaacttctt cgcacgctca actgttaacc
    13501 catgttcctg atggtagcct tcttttgaga aactttcttt tccatcatgg cgttcgtgtt
    13561 gcacccgaag catcatcatg acatcaactt gatctagtag ttcatccaat ggcatataat
    13621 gtccgtacac ttcgaattca tcgtcgtacc attctctagg acctgagaag aatacttgtg
    13681 cgcctagacg ttttaacatc tgcatattgg atttagctac gcgagagtga gtgatatcac
    13741 ctacgatggc aactttcaga ccttcaaaat gaccaaattc ttcataaatg gtcatcaaat
    13801 caagcaagca ttgggttgga tgctgtccgc ttccgtctcc tccattgata atcgaacact
    13861 ggattgtttt actttgtatc agttcgtcat aatagttctc atcaccatga cggataaccg
    13921 ctacgtctac gcctaatgct gacatcgtca gtactgtatc gtatagtgtt tccccttttt
    13981 ggacagagct tgtgcttgct tcaaattcaa tcacttctag ccctagtttt ttctccgcta
    14041 catcgaagct tttatgtgtg cgagtactat tttcgaaaaa gaggtttgta gcaaagtact
    14101 ggcgcttttg cggagtccaa ttagcacctt gcttgaattc ctgccctctg cggatcaagc
    14161 ccataacttc ttgatcagta agtgcctcaa cggtcaataa atgctttaag ctgatacgtt
    14221 ctgatttgat gatcataatg tttcctcctt agttttcttc gcttcgtgaa gtttctggta
    14281 agataagatt taaaatgatg ccaagtacag ttgctaatgc cattgccgac aatgtaaatg
    14341 tgcctacttc aaagacgagt ccgccaattc ctactactaa gataactgaa gcaatcaaca
    14401 gatttttctt tttatcaaaa tcgattttgt tctcgattaa aatcttcatt ccacttgcgg
    14461 caattactcc aaataagata aaactgattc ctgagatgac tggtccaggg atacttaaaa
    14521 tcaaagcgct taattttcct acgaatccta aaatgactgc aaatactgca gctccaccga
    14581 tcacaaacac gctatggaca cgtgtgatag ccagaacacc aatgttttca ccgtaacttg
    14641 ttacaggagg acctccgaca aaggctgcca cgatttgtgc taatccatca cctgtcaacg
    14701 tcttatgaag acccggttct tcaaagaaat tacgtttagt tagtttattc aataccataa
    14761 gatggccgat atgctctgtc atcgtcacaa aagcgatggg tgccattgtt gtgattgctc
    14821 caagatatag ctttggttca tattgtacaa agggaatctc aaagttagga acagcaaacc
    14881 aggcagcgtc tacgattggc ttagtatcca cgattccaaa cagcaaggct acgatgtatc
    14941 cgctaataat acctagtaaa atcggaatca atccgagaaa acctcttagc cacatgttga
    15001 agaaaattgt taatcctaat gtgatcagcg ctacagcaat atacttgaaa tcatacgtgc
    15061 cctgattata catagcattt gttgctgcat ttgccgcaag tcccaacccg ataaccatga
    15121 tgactggacc gacgacgatt ggaggcaaga ttttatccag ccatgctgaa ccgatctttt
    15181 tgatgatcag cgcaacaatc aaatagacta atccagttgt gactgctcct tgtgcaatcg
    15241 ctggataacc atctgttttc atcaaaagct gcatcgctgc aatgaaagcg aagctgcttc
    15301 ctaagtacgc aggtatcttt cctttagtag taaataagta caccaatgta cctagtcctg
    15361 aactgactag cgcaatacct ggatcgatac ctactaagat ggggactaac acggttgctc
    15421 cgaacatcgt gaacaagtgt tgtaaactta atcctaccca atgtcctggg gttgggcgat
    15481 cgtggatatc taacaccacg tcatcattat gaaatccttt tttctccgac atgtttctct
    15541 ctcctctaat cttcctcttt caaaatcatg atgcgatctt gtccatcaag ctcttgcatc
    15601 tctactaaaa tctcttccgc ccgagatgtt ggaatgttct tcccaacata atctgcacgg
    15661 attggcaatt ctcgatgccc acgatcgacc aggactgcta atgaaatttt tcttggtctg
    15721 ccaaaatcca ttactgcgtc cattgctgct cgaatcgttc gtcctgtata caaaacatca
    15781 tcaatcaaaa taacttcttt tccttctaag gaaactggga tgtcagaaga atgaagttcc
    15841 ggttcttctg gattttcttt tttgtcatct cggtataaag tgatatccag ttctcctaca
    15901 ggaatatcga tatcttctag ctgcttcagg cgttcggcaa ttcttgatgc aatgtagatt
    15961 cctcgtgttt tgatacctac caatacgata tcttggatac tatggtttct ctcgataatc
    16021 tcataagtaa ttcgagtcaa tgctcgcttc atggttacct gatctactac ttcttttgct
    16081 tgcattttca ttccccctac ttttttgcat aaaaaaactc ctgccctaag aggacaggag
    16141 gaatgtttag actgagcgta tactgataca ctgatagcta tactatgtca atgagcaatc
    16201 tacttatggc gcaccatacg tatccttgct cccacccttc ttagcctcac gggactaaac
    16261 ttaaaggaat tctattaagt tttatgcttt cgttgttaat tactataccg ttatctaaat
    16321 taaaatgcaa tgttttttct taatttttct aaagtttttt caaaaacttc tggaagaggt
    16381 gcttcaaaga tcatcttttc gtttgtagtc gggtgcgtaa aacctaacat ttgcgcatgg
    16441 agaaactgac cattgccttt caaagttttc ttcggtccgt atactggatc tccagctaac
    16501 ggataaccga tatacttcat atgcacacgg atctggtgtg ttcttccggt ttctagtttt
    16561 aattcaacca gagtaaatcc ttcgaaacgt tccaatacag taaaatgtgt gacagccgac
    16621 ttcccatctt ctcttatcgc ctgcattttc cggttttcct tcgaacggcc gattggcgca
    16681 ttgatggttc ctttttcgtg aggaatctct ccatggacta aagcaacata tttgcgcaaa
    16741 gaggtcttat cttttaattg ctgagctaat gattcgtgtg cctggtcatt tttggcaacc
    16801 attagcagtc cggaagtatc tttgtcgatt cggtgaacaa tacctggacg aataacgccg
    16861 ttgatcgtag aaagatcctt gatatggtac atcagcgcat tgaccattgt gccatgcgta
    16921 tgacctgctg aaggatgaac gaccattcct tgaggtttgt ttatcaccgc tacatcttca
    16981 tcttcgtaaa cgatcgtcaa cgggatattt tctgggacca catctaatgt ttctggttcg
    17041 gggatcaaga cagtaatctc gtctccttgt tttactttgt aatttgcttt gactggctgt
    17101 ccattgacag aaaccgctcc atttttcagc cacagctgaa tttgcgaacg actgtaatcg
    17161 gtgaataaat tagtcaatac tttatcgatc ctaccagatt catggtgaat cgtcgtttta
    17221 agttctgtca tttttttctt tgatcctttt catctaaaat aatataaatt aacatacaaa
    17281 tcactccaca tacaagtgtc acatctgcta cgttaaaaat cggaaagctc ataaaatctg
    17341 tctggaacat atctactaca tagccaagac gaatacggtc gataaaattg ccaatcgcac
    17401 cagctagaat caaactcaat ccaatcatga accagcgatt acctttttca cgatttttaa
    17461 tcatcaatgt gagaatcaca acgactgcaa tgagtgtcac tatagtaaag aaccacatct
    17521 tcccttctag catactccat gcggctccag tgtttcgaat atgattcagt gacaaaatac
    17581 ctggtataag atttttcgtc tctccaagcg ctagattatc agtgatccac catttgacca
    17641 actgatccac tcctactagc aaagcgctga atatccaata aataattaac aaaaaatcaa
    17701 tccttttcta tttgtttata aatatcacga ggtcgtacga tcccgagcag attaccatcg
    17761 ggattcccat ctttagtgat aagtacggct tccaaagtcc cttgctcacg aaacatcgct
    17821 tcaacctcgt aaatatgtgt tttagctgga acaaaatgat aatttgtgta ctttccgttt
    17881 tggatgatca aatccaacgc tcgtttattt gttaaatcaa ccggaccttt ttggctttct
    17941 tttgctagcc aaaacccgat attacgtaaa gtaatcaatg ctacaaattt tcctttattg
    18001 tataacggaa attgtgaata ccttttttct gctactatct ttaacagttc aagtaacgga
    18061 agatcttgtt caaaacctgt tacacgtttt gcaaatcgag gcagcacggt ttcaggctga
    18121 atcagttctt gttcgatcag ctggattcgc ttgactgtcc aatcatttgg ctctgcaatg
    18181 acaaaatcga ctgcgatccg atcatggacg atcgcattcc ttaactgagc aagctgtaaa
    18241 agatcatctt cgtattttct gatcattaat tgttttcttt gagctaggcg tctgacaagt
    18301 tcggtaaatc ccatatttcg tgcatttccc atctcgtctc tcatccattt ttcgattcga
    18361 ttgaaactga ttaaaaaaag atcagagttt gccataattt tcctccttga tcaaatatgc
    18421 ccggtttttt atatagaaaa agaacgcaat caacacaata actgcaaaaa aactgaaaaa
    18481 taaattttgt aggaaaacgg cccccaaccc agttgctaga aataaaaacg gatagatttg
    18541 aagaatcaag taattcattg tgatcacata agcaggcttt gcttctttca ctgtataaac
    18601 ggggcttttt agccaataaa aggtgacctg catcgtaaag ggcacttcca gatcaagcgt
    18661 tatcttttgt tcatgactga gaacactgcg tttttcattg ttgattctta gctgaatcga
    18721 gctacccata ccgtaaaaac cggtttttct tataaatgtc gttttcatca taccctccta
    18781 ttatgcttta gtatagctca aaatacaata aagaaaaaga atgatcctag tgtaaacaaa
    18841 attaattccc tatcgtctaa aaaaagaagc tgtagtcaaa atacagctcc ttcgatggta
    18901 gattataatc aagcttaaaa caatcccaac acttctccgt catttgtcac gtccatattc
    18961 aatgcagcag gttttttagg caaaccaggc atcgtcataa catctccagt caaggctact
    19021 aaaaatcctg cccctaattt tgggatgatt tcgcggatcg tgatggtgaa atcttccggt
    19081 gcacctagca gtgaaggatc atcagaaaat gaatactgtg tttttgccat acaaatcggc
    19141 agtttgtccc atccattctt cgtaaactct tctatttgtt tttgcgcttt tttgctgaaa
    19201 acaacaccat ttcctccgta aattttcttg acgattgttt ctgtcttttc ttgtatcgtt
    19261 tcttctaggc ggtataatgg cttgtaatta gcttcttttc tatcaatcaa tcgtactaca
    19321 gcttttgcta aatcaacgcc gccttctgct ccatctgccc atacactcgc tctcttggca
    19381 agaatcccct gattttcaca caagtgctcc aacagtgtga gttcattgtc tgtatctgtt
    19441 acgaattcat tgattgcgac gatcacaggt agctgatatt gttccatatt acgtatatgg
    19501 cgctttaaat ttgcaaaacc tactttcaaa gcatcaagat tctcattttt aagttcatct
    19561 tttttcattc cgccatgcat tttcaatgca cggacagtgg cgacaatcac cacagcatcc
    19621 ggcgcttttt tcaagttagg tactttgata tctaaaaatt tctctccgcc aagatctgca
    19681 ccaaatcctg cctctgtgac aacgtaatct gctaatctca atgctgtctt ggtagctaaa
    19741 atactattgc agccatgagc gatattggca aacggtcccc cgtggacaaa agctggtgtt
    19801 ccgtaaattg tttgtacaag attcggcttg attgcatctt tcagcagtaa tgccagagcg
    19861 ccttctgctt tcaagtctcc agcagtcaca ggctgacggt caaatgtata gccgacaacg
    19921 atccttgcaa gacgagcctt taaatcttca aggtctgccg caagacacaa gatagccatg
    19981 atttcgctgg caactgtgat atcaaaccca tcttctcttg gaacaccttg gattggccca
    20041 cccaagccaa caattacttt acgcagttca cgatcattga gatcgactac ccgtttccaa
    20101 atcactcggc gggcatcgat gttcaattca tttccttgat gaatatgatt atctaaaaga
    20161 gcagataatg cattattagc tgttgtgata gcatgcatgt caccagtaaa atgcaagttg
    20221 atatcttcca taggcaatac ctgtgcatat cctccgcctg cagcaccacc tttgattccc
    20281 atcacaggac caagtgaggg ttctcgcaat gcaataacag attttttatt gattttattg
    20341 agcgcgtctc ctaaccctac agtgatcgtt gactttcctt cgccagctgg tgttggattg
    20401 atggaagtaa ctaagatcaa atgcccctca gcgttatcct ttgatcgatt gattccagaa
    20461 aaattgattt tcgccttata tttcccatac agttccaaat cgtcttcctt aagatctaat
    20521 ttactagcca cttcaacaat cggttctagc tctgtttctt gtgaaatttg cagatcattc
    20581 ttcatttgat tacccctttt cacgaacttt attcaacaaa atatcttctt tgttaagata
    20641 tgccaattat accttttttt attcagaaaa aaaacataaa attacaggtt tttaatttat
    20701 ttgacgtact tataaatact ctttataatg aaggctatga tcagacttta gaaaggtcgt
    20761 gagtgctttg accacaggaa ttgtaaaatg gtttgacaac aaaaaaggat acggctttat
    20821 cagttatgat gacacagaag aaatttttgt acattttact gcgattgaag aagagggatt
    20881 caaaactttg gaagaaaatc aagtggtcga atttgagatc atcgaaggga atcgaggaac
    20941 acaagctgcc catgtcaaga aaggcaacgt tcagactacc gatactagta tgcatgaata
    21001 gataaacaaa tagagtgaga cgctaaacgg gatgaaccgt acgtctcact cttttctttt
    21061 cctgtaaaaa ttcgtttttt taggttctga tttttaaaat tagctttttc tttttttcgt
    21121 ataaggataa ggaattgatt ctgatttggg tccgtttttt tcaaaatgat caaaaaggac
    21181 tacttgatct ttttttcgca tcatgaaaac agatggggct ttctcatctt gcaacatcat
    21241 ttgcacccca gtattagttg gcgtcaaaga tcgaatctgt ccgacagata tttctcggtc
    21301 tttccaaaaa gcagcataac gtataatcac agagtttgat tttaaaataa aagaacgccg
    21361 caaacctaga aatagaaaaa caagaaaaat acctaaaaca aaattgcttt tccaataagg
    21421 acctgtgttt tctaaagaaa gaatcagact aaaaaacaga atgatcaagg tcaatgacca
    21481 atagatgatc gtatgtgcca gttcaggctg ccatcgaata ttttttttca ttctctaacc
    21541 tctcaccgat tcagtaatga tataatctta ccataacatt agtttgaaca aaaaggagaa
    21601 tctcttttta tgttaaaagt atacattgat gcctctacaa aaggcaaccc tggtcctagt
    21661 ggaggtggaa tcttgattgt ctatcaaggt aaacaagaac agctatctat cccgctttct
    21721 atagggacaa accatcaagc agagttcgaa gtctttttaa aaactttaga atttctaaag
    21781 aaaaacgact tacagaatga aacgattttc tgtttttcag acagcaaaac actagtttct
    21841 acggtcgaca aaaacgcaac gaagaacgag ctcttccttc cctaccttca aagaatccaa
    21901 gaacttctat ccgaattttc tttattgatc ctgcaatggt tgcccgaaaa caaaaataaa
    21961 ggagcagata atcttgcacg tcaggctctc cataaacaat taaaagaaaa aaagactctt
    22021 taaattaaaa actttaagga gtctttttat agtttctcat ttaatataaa agataattgt
    22081 gatcaaacgt aatttccaat tggtaatctc cgattttttc ttctatttga ctacgtaaga
    22141 ttctttctag ttctgtatca acaaactgga atttctcagg gaccactaca tcaaattgca
    22201 gcgtttttcc ttgatgaatt actctaaaat catgaatatt aagccctgta cctgtttcaa
    22261 gaagaatttg ctttaactgc cgcaagatat tatagtattt ttcgttatca acaggcattg
    22321 gatccaagtg acagacaagt tccacatcca aagacttttt aaagtctttt tctatcagat
    22381 caataatctt atgagccaca ttcaaattca ttgattcatc tacttcgatg tggactgatg
    22441 caaagcgttt attgggtcca tagttatgca ccaataaatc atgatagcca agtatatcat
    22501 cgcaagcatt taaatgctct tccatttctt caatctctgc tggcgttggg cgacttccta
    22561 atagttcgta tacaaaattt cgaagcatcg tcaatccact ataaaggata tataatgcta
    22621 aagcaaaacc tatatatcca tcaatacgcc atccagttac ccattcgatt gctgctgaaa
    22681 gcaatacagc cagtgtagta aagacatcat tataactatc tgttgctgta gctctcaatg
    22741 tttcagaatc aatggattgc gcaataacct gatacatttt gccttgtgca aatttcaaaa
    22801 agatggaaat gattaggaca aaaaagacga tgggtgttaa agagacattt tctggatgga
    22861 tgattttttc agcagaagac tctaaaaatt gaaatcctac ataagtaatg atgatcgaaa
    22921 caaataaccc actgatatat tcgaagcgtt cgtgtccata aggatgttcc tgatctgctg
    22981 gctttgcagc aattttaaat ccgatcaaag tcaatatgga tgaagcagta tctgatagac
    23041 tgttcactgc atcagccata atggagacac ttcctgaaaa aagcccgatc attagcttag
    23101 agacaaacaa gatcagattc gtaaccaatc ctaagatacc cgctagtact cctttttttg
    23161 tccgctgttg cggtatttgt ttcttttttt cttcttgttt cttagccaag ttttttaccc
    23221 cttctagttt gcttgttgct caggtaaaaa gatggagagg acgattgttt tcctctcctc
    23281 tcttcctttt tctatctatc gtgcgtccta ttactattaa aagatggtca ttattctggt
    23341 ttcaacggtg ttgctgcaaa taacgctttt gctagtaatg gtgttatgat tcccgcacct
    23401 attgcttctg gtatcccatt gattgctgca acccctgcta aggttttaaa taaaagagca
    23461 gagtctacac cataggcatc tgccgttgca cctgtataaa ataatcccat gaatcctaac
    23521 actaagactg tattgaccaa tgaacccagt acccctgcaa aggctgagct gatcgttatt
    23581 gatttatttt tttgataaat ccagtggaaa accaagcctg ctactaagcc aacaagtact
    23641 ctgggaacta ccgagataat cggattcgtg aacactaatg tatcaaatgg cgttgttggc
    23701 atggcatagg cacgaacaat tgtagcgatt ccccaaaaca agccaatcac catgccatct
    23761 tttgggccta atactactgc agcaataatt actgtgatat ggataattgt taaactaatg
    23821 aatcctaatg gaataaaccc cagccaagga accatcgctt gtacgatgat gattgctaac
    23881 aagatcgcac gtaagactag tcgaaaggtc ttatttctac tattcatttt ttcacccctt
    23941 tttatttata ctaatcgtaa aaatttctgt cactttcgtc aactaaagac catccgaatc
    24001 cgaccatttg attagatgcg ccatccaatt gaaaaaagta tgagggcaag acttgtttgt
    24061 cttcgccccc ataatcatgt ttcgttcaat gtttgaactt ttgtttttct gtcaaacgta
    24121 aacgccctat tgttgcgcaa cccattcttt cgcagcttta agtgcatctg gaataccagc
    24181 aggatttttc ccgccagctt gtgccatgtc tggacgtcca ccaccgccac cgcctacttt
    24241 cggtgcgatt gctttaatca agtcgccagc ttttagtcca gcttcatttg attctttcgt
    24301 cattgccgct agcagactga cttttccttc ttgttcgttt gctaaaacaa gaatatctga
    24361 aatatttttt tgtttccatt ggtcagctaa ttgacgcagc tgattcatat ctttcacttt
    24421 tacttgtgct gcaatgattg tttttccatt gatcgtttct ggatctttga atacatcacc
    24481 agcttgttga ttcgctaact tgctagctaa ttgttcattt tccttttgta gctctcttac
    24541 ttgctgttgc aattgttccg cttttgaaac aacttctttc aattgaggtg atttaacaat
    24601 tgttgctact tgttttagtt gtttttcttc ttcttcaagt agttcgtacg cttctttact
    24661 tgttacagcc tcgattcgtc gcacgcctgc accaattcct gattcagaaa cgattttgaa
    24721 gattccgatg ttttctgtat ttgctacatg tgtgcctccg cacagttcga ttgaccagcc
    24781 gccaatattt actactcgaa cgtcatgtcc gtatttttca ccaaacaaag ccattgcacc
    24841 catgtttttg gctgtatcga tatctgtttc aattgtttca actgggatag cttcccagat
    24901 tttttcgttg acgattcttt ccatttcagc taattcatct gaagtgattt gaccaaagtg
    24961 ggtaaagtcg aatcgtaaat gtccaggagc gactaaagaa ccagcttgat ttgcatgctc
    25021 gccaagtact tctttcaatg ccttgtgcag tagatgggtt gctgtatggt ttttgatgat
    25081 ccgattgcgc atcgattgat cgatcaatag atgataggtt tgtccttcac tcattggtgc
    25141 ttttacttct acggtgtgca taaattgacc attaggcgct ttttgaacat ctgtaacaac
    25201 tgctacgatt tcgcctactt cattcatgat ccatccttga tccgctactt gcccacccat
    25261 ttctgcatag aaaggtgttt gatcaaagat catttgagct tcaccttctg cgacttcatt
    25321 caaaagagac tcacctttaa cgatgaccaa taattgacta tctgattctt gttctgtgta
    25381 tccaatgaat ttactttcta ctttgatatc tgtcaataaa gcagattgta cccccattga
    25441 tttttcagta ctgcgggcag agcgagcacg ttcgcgttgt gcatccattt ctttttcaaa
    25501 accagcatga tcaactttca gtccttcatc ttctgccacc tcttccgtta attctaccgg
    25561 gaagccatat gtgtcgtata gtttgaagat gtcttttcct gctagagtcg tcccgttttc
    25621 gttttttact tcttggatca cttgatttaa gatttccaaa ccttcattga ttgtttcatt
    25681 gaaacgttct tcttctgtac ggataacttt ttcaataaat tctttttgtt gaagtacttc
    25741 aggataataa cttaccatga tttccccaac aacagggact aaacgatata agaatgcttg
    25801 ttcaatacct aattttttcc catgcatgac agcacgacga agcaaacggc gtaagacata
    25861 ccctctccct tcattcgatg gcaatgcacc gtcgccaata gcaaatgaaa gggcgcgaat
    25921 atgatctgcg attactttgt aagaaatatc tgttactggg ttttcaccat attttacttg
    25981 tttgcttagc ttttctacgg cgtggataat aggcataaac aagtctgtct caaagttcgt
    26041 tgacgcatct tgaacgattg agaccatgcg ttccaatccc atccccgtat caatgttttt
    26101 atgaggaagt ggttcaaatg tgttatcagg cttatggttg aattctgaaa atactaagtt
    26161 ccagatttct aaataacgtt cattttctcc tcctggatag ttttcaggat cgtcttctgc
    26221 taaatcgtta taagcttctc cacggtcata gaaaatttcc gtatccggac cacatgggcc
    26281 tgcaccgata tcccagaagt tgtcttctac atcaataatg tgatctagtg gcaggccaac
    26341 ttcttcatgc cagatgcgtt ttgcttctgt atcttttgga taaactgtta cataaagttt
    26401 ttctggatcg aatgccatcc attttggatc agtcaaaaat tcccatgccc agtggatggc
    26461 ttcatttttg aaatagtcac caatcgaaaa attacccagc atctcaaaca tcgtatggtg
    26521 ccgtgctgtt ttaccgacat tttcgatatc atttgttcga atagattttt gggcatttgt
    26581 gattcttgga ttttctggca caactgaacc atcaaaatat tttttcaatg ttgcaacacc
    26641 agagttgatc cacaataagg ttggatcgtt cacggggatc aaagacgcac taggttcaat
    26701 cgtatgtcct ttagattgga agaaatcaag aaacatttgt cgaacttgtg cactacttaa
    26761 ttgtttcatg tcattacctg ctttctataa attaaataca aaaaaacacc atcacagcca
    26821 aggacgaaaa ctcgcggtac caccttgatt gcaatgatgt gtaatcatta cctcttaaac
    26881 tcgataacgc tgagctgcgt cggtatttct accaaaatag aaaaagggag caatttgatt
    26941 agtgactatt cttttttcag ccaagaaaga attttctgtg agtcttaaaa aacaaatcat
    27001 atccttttcg tacttaatta gtatacgcat tctattgatc actgtcaata tctcaatttt
    27061 tattttcatt tccttttggt catactccac gatttttggt acgataagaa taaaggaatc
    27121 aatacatctc tgctattcat gacaaggagg aatatgatga aaaaaatagt tggagcggat
    27181 gaatggatac gcgcagctag ctgctttttg agatatcaag tttttgtatt agaacaaggg
    27241 attcctgcag aactagaatt cgacggaaaa gatatcccgc aacaaaccta ttatctattt
    27301 cttgatcaaa aaagaccagt agctactttg cgttatgaaa agaaaacacc tacttgcttc
    27361 aagccggaac gattttgcgt agcaaaagaa taccgaggaa aagggttagg cggtcagttg
    27421 cttgaagctg ctgaaaaacg ggcggtttca gaaggttgtc agactagtta tgtagtagct
    27481 gaaatgacgg ctgtagattt ttatgaaaaa caagggtatc atacttgcac agaacctttt
    27541 attgaagatg aagtactttg tatcggaatg aaaaaaagtc tagcttaaaa acaagagatt
    27601 gtgacacgcc ttttgtcaca acctcttgtt ttttatttat gtgaattttt cttattttta
    27661 cgagcagtac ggctttgctg tctgcgttcg attttgcgtt cttttttatt tttttctgca
    27721 attgcccaat cgattttttt cttataacca ggcttgatct ttttcttttt cttcttcaca
    27781 agaccaatca gcgtgggatc taatacatct tttgattttt ctcgtttggc acgtctatta
    27841 cgatcgtatg ttttgacgat ttccccgttt ttgatttctt ttggttcaaa tgagacgccc
    27901 aatttttcta tcgcatcaat ggcttgctca tcatttggcg aatataacgt aatggccgtt
    27961 ccttttaagc cattacgtcc agtacgtccg acacgatgga taaagaagtc tagatcttct
    28021 ggaatttctg cattaataac atgagagaca ccttcgatat cgatccctct agcagctaaa
    28081 tcagtcgcta caacatattg atactccaga ttctgtactt gtcgcatcac tcgttttctc
    28141 tctcttgggg tgatgtctcc atgaatcttt gctactttca agccttggtt tttcaagtaa
    28201 tcggcaattt catccacatg ctgttttgta ttggcaaata cgattgctaa ataaggatga
    28261 ccaattgtca gcagttgata aatcatttga ttctcatctt taccttttgt tgaaatcagc
    28321 caattttcaa tgtcttcaga aataactgct tttggtttga tttcttcaat gattggattt
    28381 tccatgtatt ttcgtaagaa tggacgaagt ttttctggaa tagtggcaga aaaaactaaa
    28441 aactgcagct tttctggtaa tcgacttgca atttggtcta cttcatttaa aaaacccata
    28501 tccaatgtca tatccgcttc atcgacaaca aatgcaaatg cggtgtgaat cttcagcgct
    28561 tgttcattca tcatgtctaa tattctacca ggcgtgccta ctacaacctg tggctgttgg
    28621 tgatgcagac gatttaattg acgctgtttg tctgtaccgc cgacaaaatt cgagacacgg
    28681 atctccggtg tagaaaattt agcgatttgt gtagctgctt catagatctg tgcagctagt
    28741 tccctacttg gagctgtaat aacaacttgt acttcctctt tttctgcatt gattttttca
    28801 aacaaaggca acaaaaacgt atgtgttttt cctgtaccag tttgagattg cccaatgata
    28861 ttttttcctt ttgcaattaa aggaatcaaa cgttcctgga cctctgtggg ctgtttgaag
    28921 ccctttgcgg ttaacgcttc attgataaac ggtttgaagc ggaatatatc aaaattattc
    28981 attcgtgcac ctcttctctt taaattatca cgactttggc attataacac agacaaagcg
    29041 tttttgctca gctaatttcg agaatcatca tcctttgttt ggccaatcgt gctaacagta
    29101 tatgtgtgac tagctttttc ataaaacaga atccgttttt ttctcaaaaa tgatagcaag
    29161 atatttaaaa taaaaatacc ttgtagtaac aagacaccga gagaaatgaa tactgcactc
    29221 atctgcaaca ccgtattcgt tgtcgaattc atgatttgct gaagcaactg ccccaaccag
    29281 cttaaaccat aaaaaagaaa gtacagatac ccgtagcgga tcatcaatgc ttttaaagaa
    29341 attcgttcgc ggtcttcttc caccaaacgg atacgcacaa tttttttgcc aagtgtccat
    29401 ccattggtta taaacggtac aatcataaag tataccccta cttctaataa aagccaccag
    29461 atatgagaag taactgcccc tgaatcgaac gcaattttaa agaaaatcgc cgctaccaaa
    29521 ttaataagag ataaaaatgt ccagtcgatc aaataagcga ccaagcgtcg agtcaatgag
    29581 acagtctttc ctttttcata agaaagttca tccattcgtc ttcttgtagg aagcataaat
    29641 gtaaataacg gcgtaacgac aaaaccaatg attccaccca atgtatttgt cactaaatca
    29701 ttcacatcaa ataagcggta tggtcttggg tagataaaat aaagtccact tagctgcgtc
    29761 aattcaaaaa atagagaaag gcagaaacta gcaatcatcg ttttcataaa agaaagccgg
    29821 aaataatatc ttaaataaat gccaaacggt atgagtaata aaacattaaa agctggttcc
    29881 aaaaatacac tctgcttcat tgccggcagg taggtactag gttcagacaa gaccaatacc
    29941 gtgttgtctc tgaaatgttg ccatgaagca aataaatgca gctccatctt tggccctgtc
    30001 atttgggcaa ccgtctcctt tgccggaagt ggtaagatca ccaaaaaata cgcacacaat
    30061 aaataaaaaa cgaaagaata caaaataact gcccttgtta ctagaaatgt tccatacttt
    30121 cgatattcat aaataaaaaa aacagatgag atcgctaagg ctaaaaatgg aaaaacaatc
    30181 agcgcaaaac gaatcggttc gatataactt gccatatgac tcctccttga ttctttgtat
    30241 ctctcttatc ttagcagtcc tttgctgttt caagcaagta acgaggctat tatttctcat
    30301 ttctttcaaa gtaaagtaag ataaacacaa agggggtgtc gagatgctga atatgtactt
    30361 tgtttttggc gtacctattt ttttactgtt cctttatgct acgatcgctt atgtaagaaa
    30421 aagaactaca attcattatt taggatttat tctcctgatt atttcgggtt tcatgctagt
    30481 cttcaatctt cagacttggc agcaagcact tcttgaaatg gataaaatga ctccacatgc
    30541 tttgtctaaa gtgcttggct accctgtcta tctgatttgg cttcccattt tcatttctgg
    30601 ttgcttggtt ttattaaata tttatcgcgg cgtacgccga atagttcagt tacgcaaatc
    30661 aaagtaaaag acagaaatcg gttgagcccg atttctgtct tttactttgc tatttcatcg
    30721 tagacaaaac gacatttacg tgatcaaaat taacgagtac ttttgacatt tcttccacgt
    30781 actcctcatt taaataaaat attttgtttg gcagagaagt gcagttctaa taaaattcga
    30841 atgttttagc tatctacgtt ttaaatagag ataaatcggg ataccagcaa gtgtcaatac
    30901 tatccccatc gaagctaaaa aggtctgagt gataagcgtg cttgatacga taaaagtccc
    30961 tccaatgatt gctactagtg gaataaacgg atacattgga actttgtatg gtcgaaacaa
    31021 atcaggttct tttttacgaa gaagaatgac accaacaaag accatcgtat aaaaaatcca
    31081 aatgacaaag atcagcatat ccgttagtgt atcaaaacca ccgatcatca tcatgccaat
    31141 agcgatgact agctctaaga tacctgcggc tacaggaact ttagttttat catgaagttt
    31201 agcaaagagc ttgctaaaag gcaggttgtt ttcttttgcc ataacataag ggagacgcat
    31261 tccagtaagg gtatagccat tgatggttcc ataaacagaa atcaagatac caactgtgac
    31321 cagtcttcca ccgaagccgc caaaaatcat ttttgcaacg tcacttgccg cattgctgtt
    31381 tcctgcgact ccgtcgatag atgcggttct taagaacacc gcatttacta ataaataaac
    31441 gatcatgatt ccgatgattc ctaaagaaat tgcttttggc aaatctttcg ccggcttttt
    31501 caattctccc gaaatatttc ctacgtgtat ccaaccgtcg tatgcgaaca tcgttgctag
    31561 caagcccgct cccaaggctg agaaaaatga aagattttct cctgcttgga tcggaaacag
    31621 ttggaagtct actccttctt gtcggaacaa accgaaaatg acgatcacaa acaaaggaat
    31681 aagcttgcag acaagcgtaa tcgactgaaa agcccctcca gctttagaac ctaaaaaatt
    31741 gatcaacagg atcgatacag cagctgtaac agctacggga acaatcattg actgggaaag
    31801 accaaataga ttgacgaact gtgtaccgaa aatgatcgac aaggctgcta catttgctgg
    31861 aaaataaatc acgacttgcg cccagcccaa taaaaaagct gctgtatttc cgtaaatccg
    31921 ttcgatatat ttaatcatcc ctcctgtttc tggaatagca gctgccagtt cagctcctgt
    31981 tagtcctgca cagacagaaa tcataccacc gagaaaccaa gaaaacatat gcaaactggc
    32041 ggatcctgta acttctgcta cgcttgcggc tttaaaaaat acccctgcac cgatcactgt
    32101 gcccataaca gtcgataaag cagtaaaaaa tcccatcgta cgttttaatt cattttctat
    32161 ttttacttct tttactggcg tggcttgata ttcttccatc ccttgtcccc tttcatacca
    32221 tagccaatcc caaaagtata aaaaactttt tggatgtggt tcttgtttta taccgtctct
    32281 accaattttt ctttcagttt ttccaacata tcctttgtca tcacatctaa gtcgtatttc
    32341 ggcgaaaagc cccattcctc ttgcgcacaa gaaacatcta gtgaatttgg ccaagattct
    32401 gctattgact gacgtacagg atccacatca taatccattt caaaatctgg tatgattttt
    32461 tgaatagatg ctttgatctc ttccgggtca aaagacatcg ccgatatatt gaaggcattt
    32521 cgatgaacca atcgatcagg atctgcattc atgagtttta taatggcatc gatcgcatct
    32581 ggcatataca tcatatccat tgatgtacct tgatcaatga aactagtgta ctttccttct
    32641 ttgattgctg aataataaat atcgactgcg tagtctgtcg taccgcctcc tggcaaggtt
    32701 gcataagaaa tcaatccagg gaaacggaca ccacgagtat ctacgccata tttcacataa
    32761 taataatcac atagtagttc tccagctacc ttcgttaccc catacatggt tgtaggacgc
    32821 tgaagagtat cttgtggggt atgatctttt ggagtatttg gaccaaacgc gccgattgaa
    32881 cttggcgtaa aaaatttcag ctggaattct ctagcgactt ccaatgcatt gaccagccca
    32941 gtcacgttca aattccaggc taattgtggt tttgcttctg caacagctga caaaagagca
    33001 gccaaatgaa tcaatgtgtc cacttgatat tgttctgcta tgctgcgcat tttttcgtaa
    33061 tccattacat ctaggatctc aaagatatcg tttttctcaa tgacttcagg catgcgtata
    33121 tctgtcgcaa tgacattttc actgcctagt tcttgacgta gccgtgtgat caactctgaa
    33181 ccaatttgtc ctaaacatcc tgtcaccaat acttttttca tgatgatcct ccctgatctt
    33241 ttttactact atcttcagat gattaacaat atatgcgtga acatgttctc taattttaaa
    33301 tagacgaaaa aactaaattt agttaaataa tttccatttc ttttcctatt ttttgataaa
    33361 ctgctactgc ttcatcaagc atttccctcg tatgttccgc agtcggcata tttctgatcc
    33421 tgcctgtccc aagaggcaca gttggataaa cgattggttt agcataaatc ccatgttcga
    33481 tcagcttctt agagaaagtc tgagtcactt tttcgtctcc caaaatgact ggagtaatag
    33541 gtgtttcaga cataccgatg ttatagccta cttttttcaa ttcttcttta aaataattag
    33601 cattttccca aactttttcg acaagttccg gatgttcttg catcaaagta atcgaagcca
    33661 atgcagctgc agctgcacct ggagttagcg aagtagaaaa taggaatggc cgacttctag
    33721 ctttcaacca gtcgattagt gttttcgatc cagctacata acccccaaca acacctatag
    33781 ctttcgataa cgtgcccatt tgcatatcga ttttgtcgct taatccaaaa tgcttgacgg
    33841 ttcctgcacc ttttccagtt acgcctgagc cgtgcgcatc atcgacgtag gtgatcagtc
    33901 catatttttc aacaatcgga ataatttccg gcaatcgtgc aatgtctcca tccatggaga
    33961 aaacaccatc tgtgatatac atgatttttt tatatttctt actttctatc gcttcctttg
    34021 cttttttctc aaggtctttc atatcttgat gtttaattcg gatgattttt gctccggata
    34081 agcggcaacc gtcaataata gatgcatggt ttaattcatc cgataagata gcatcttctt
    34141 ttgtcattac tgcagagata gcgcccatat tgcagttgaa tccagattga aaggcgattg
    34201 ctgcttctgt ccctttgaat tctgcgattt tttcttctaa ttgctgatgg attttcagcg
    34261 aaccattgat cgttcggact gctcctgctc ctacaccata agtttcggtt gcttcaatac
    34321 atgctttttt caattcttcg cgattggcaa atccaagata attgttggat gctagattga
    34381 tcatcttttt tccgtctacg atgatacaag caccattttc actttctagt atgtcgatcg
    34441 tattgtataa ccccttttct ttcagttgat ccaattcttt ctctaaatac attgttagtt
    34501 ctttggaaga cattgtctcc acctccatat tcatctgtct tgcagaacat accaaacata
    34561 tatcgtgtca ttcatctaca aagcaagtat gctatatttt tgataacgct tacactgatt
    34621 atgagaatta tttaaccaca ttttttattt acagtatctt tttactttca aatgacttat
    34681 atagtatgaa caattacctt ttagataatg atctatttta ctctacctgg gcagataaat
    34741 acaacacaac cattgataga agccctttcg ttaaaatcaa ttgtattctg aatatttaat
    34801 ttatttattg catagaccaa taaaaataca taaaatttcc atcttcgttt atcagcaatt
    34861 tttaatttta ctctctgaat atttcttaaa agttttactt gttgaattcg aaaaaaggac
    34921 tgtgacaaaa gtcttgtcac agtcctattc ttccgaa
//
LOCUS       DADGKS010000022        34688 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.022, whole genome shotgun sequence.
ACCESSION   DADGKS010000022 DADGKS010000000
VERSION     DADGKS010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34688
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.022"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            591..1280
                     /locus_tag="JXV47_001210"
     CDS             591..1280
                     /locus_tag="JXV47_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1487264.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="JXV47_001211"
     CDS             1267..2475
                     /locus_tag="JXV47_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAX1487265.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="JXV47_001212"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="JXV47_001212"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HAX1487266.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="JXV47_001213"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="JXV47_001213"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HAX1487267.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6578..7273)
                     /locus_tag="JXV47_001214"
     CDS             complement(6578..7273)
                     /locus_tag="JXV47_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HAX1487268.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="JXV47_001215"
     CDS             complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="JXV47_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HAX1487269.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8472..8663)
                     /locus_tag="JXV47_001216"
     CDS             complement(8472..8663)
                     /locus_tag="JXV47_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HAX1487270.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8684..9574)
                     /locus_tag="JXV47_001217"
     CDS             complement(8684..9574)
                     /locus_tag="JXV47_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HAX1487271.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9561..10328)
                     /locus_tag="JXV47_001218"
     CDS             complement(9561..10328)
                     /locus_tag="JXV47_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAX1487272.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="JXV47_001219"
     CDS             complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="JXV47_001219"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HAX1487273.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="JXV47_001220"
     CDS             complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="JXV47_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HAX1487274.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="JXV47_001221"
     CDS             complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="JXV47_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HAX1487275.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14944..15282
                     /locus_tag="JXV47_001222"
     CDS             14944..15282
                     /locus_tag="JXV47_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487276.1"
                     /translation="MSPFRSAALEEESDPRINDVVLSTGNINQKYIVRDIVFVVECLE
                     ADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQKKRDGKYFLELFAYGT
                     VIQFIQTTIG"
     gene            complement(15450..16208)
                     /locus_tag="JXV47_001223"
     CDS             complement(15450..16208)
                     /locus_tag="JXV47_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAX1487277.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16226..17044)
                     /locus_tag="JXV47_001224"
     CDS             complement(16226..17044)
                     /locus_tag="JXV47_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAX1487278.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="JXV47_001225"
     CDS             complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="JXV47_001225"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HAX1487279.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="JXV47_001226"
     CDS             complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="JXV47_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HAX1487280.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18173..19507
                     /gene="dnaA"
                     /locus_tag="JXV47_001227"
     CDS             18173..19507
                     /gene="dnaA"
                     /locus_tag="JXV47_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HAX1487281.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDIKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19705..20835
                     /gene="dnaN"
                     /locus_tag="JXV47_001228"
     CDS             19705..20835
                     /gene="dnaN"
                     /locus_tag="JXV47_001228"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HAX1487282.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21064..21306
                     /gene="yaaA"
                     /locus_tag="JXV47_001229"
     CDS             21064..21306
                     /gene="yaaA"
                     /locus_tag="JXV47_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HAX1487283.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21293..22417
                     /gene="recF"
                     /locus_tag="JXV47_001230"
     CDS             21293..22417
                     /gene="recF"
                     /locus_tag="JXV47_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HAX1487284.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDSRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22414..24360
                     /gene="gyrB"
                     /locus_tag="JXV47_001231"
     CDS             22414..24360
                     /gene="gyrB"
                     /locus_tag="JXV47_001231"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HAX1487285.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24380..26851
                     /gene="gyrA"
                     /locus_tag="JXV47_001232"
     CDS             24380..26851
                     /gene="gyrA"
                     /locus_tag="JXV47_001232"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HAX1487286.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27087..27386
                     /locus_tag="JXV47_001233"
     CDS             27087..27386
                     /locus_tag="JXV47_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HAX1487287.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27436..27948
                     /gene="ssb"
                     /locus_tag="JXV47_001234"
     CDS             27436..27948
                     /gene="ssb"
                     /locus_tag="JXV47_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAX1487288.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27974..28210
                     /gene="rpsR"
                     /locus_tag="JXV47_001235"
     CDS             27974..28210
                     /gene="rpsR"
                     /locus_tag="JXV47_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HAX1487289.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28353..30326
                     /locus_tag="JXV47_001236"
     CDS             28353..30326
                     /locus_tag="JXV47_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HAX1487290.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30332..30784
                     /gene="rplI"
                     /locus_tag="JXV47_001237"
     CDS             30332..30784
                     /gene="rplI"
                     /locus_tag="JXV47_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HAX1487291.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31058..32425
                     /gene="dnaB"
                     /locus_tag="JXV47_001238"
     CDS             31058..32425
                     /gene="dnaB"
                     /locus_tag="JXV47_001238"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HAX1487292.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33205..34497
                     /locus_tag="JXV47_001239"
     CDS             33205..34497
                     /locus_tag="JXV47_001239"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HAX1487293.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10563 a         6737 c         6861 g        10527 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgcggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tgtattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 tgtcacagtc ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc
     6541 ctagatatct agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac
     6601 ttccaataat cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga
     6661 taatgataac tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg
     6721 cagaaaacag tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca
     6781 ttcctggttt cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca
     6841 tcatataaaa gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag
     6901 ctggcgttgt tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa
     6961 gcaacagcaa cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg
     7021 ctggcttatt gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg
     7081 ttcttccgcc tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt
     7141 tttcttcttc agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt
     7201 gatttctttt ggttaatttt gtttctaaac tattgttttc ttttacgatt gctcgtaatt
     7261 gttctggttc cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca
     7321 aaagacattc taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa
     7381 taacattacg tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc
     7441 ttcttttgct gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc
     7501 acggataaat ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat
     7561 tccttttttg aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa
     7621 gcctaacaaa tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa
     7681 agcttctaaa aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg
     7741 agcactgacc acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac
     7801 ataatgattc gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat
     7861 tggttttgtc gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc
     7921 gatcgttcgg gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag
     7981 ttctgccact gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt
     8041 gttgatagat tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag
     8101 tggatcaaca cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg
     8161 acaaatagcg tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt
     8221 acttgcgcct tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt
     8281 tttcggatgt acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc
     8341 tacgttgggg tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat
     8401 cgcattaaac aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc
     8461 cataaattta ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca
     8521 aaatctcgac gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct
     8581 gcgcccattc gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca
     8641 acgatatcgt gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt
     8701 gaatattcaa gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga
     8761 tcttaccttt cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac
     8821 gatcttcgct ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct
     8881 tttcttttcc atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta
     8941 aattttcagt tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta
     9001 acagcgtacg ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat
     9061 ccggtaaaga aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac
     9121 tagctacttc tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt
     9181 cttctaacgg attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg
     9241 cttcttcgtc aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg
     9301 ctcgaaaacg tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga
     9361 tgatgggttg aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt
     9421 cttcaaatgt tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga
     9481 caacggtatc atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat
     9541 cgattcctcg gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct
     9601 tggtagactt cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta
     9661 ggtgcttctg ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag
     9721 tatttacgta cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc
     9781 agtaagactc cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta
     9841 ttcagtaatt ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc
     9901 gaatcacttg ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc
     9961 aaaatataat catactgact gcttacttct gctaaagatc cttttaatct tgattctctt
    10021 gccatcattg acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata
    10081 ctcaaatttt cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga
    10141 acatcataga tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt
    10201 ccttgtgcat ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct
    10261 agattcaccg tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt
    10321 tgtgccatct cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg
    10381 ggtatttctt tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga
    10441 cattcggcaa ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt
    10501 gttttgcttc tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt
    10561 cttgtttagc caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag
    10621 cagtgacaag gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt
    10681 catgatataa ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc
    10741 gtttattcag agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta
    10801 tgctaggaaa ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta
    10861 cttcaaatgc taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg
    10921 taatagctgt aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga
    10981 attgattcat ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt
    11041 cttctggtat cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc
    11101 cctactttaa cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg
    11161 aaaagtaaga aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga
    11221 agagagaact agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta
    11281 cgtattacgc tggttcactg actttcgcaa tcttcccttg ttcgatatag accattagga
    11341 tacttaggtc tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt
    11401 ggattttctg caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga
    11461 tgttttctgg aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt
    11521 ttttgatgta gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca
    11581 attcttcatt ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta
    11641 aaaagtcgct tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt
    11701 cttggacttc ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa
    11761 ctgcttcttt tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt
    11821 gacccatttc tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag
    11881 cacgtgaagt cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca
    11941 tgacaccgat gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca
    12001 aagctgcatt gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac
    12061 catttgtttg tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga
    12121 gctggtgtgg ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt
    12181 tttctaatcc agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag
    12241 ataaaccttg aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat
    12301 gacgtggttt gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc
    12361 ctaccccttc aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt
    12421 ggtgagtcgt ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac
    12481 tatctggtgt gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa
    12541 cagaatagtc gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga
    12601 tagcaaagcc aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg
    12661 gacctgatga atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg
    12721 taataacaac tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa
    12781 caccatcttc gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt
    12841 tttcgatcgt atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg
    12901 ctcggacagc tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga
    12961 tattcttacc catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg
    13021 gtccgcctac agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta
    13081 ataatgtttt tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg
    13141 cgccaacaac gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc
    13201 ttttattttc ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg
    13261 tcgccgacaa cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc
    13321 acaggcattc ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct
    13381 aacaacgcga tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg
    13441 ctgaagaata aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg
    13501 gaaattgaaa aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt
    13561 gctggcaaat ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat
    13621 aattgttcat cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct
    13681 gcttctgcta atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt
    13741 tcccgaattc cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct
    13801 tcgattacat ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac
    13861 aaatggttta acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac
    13921 ccttcccgca gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg
    13981 atcatctgcg ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct
    14041 ggataatcaa tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag
    14101 cggatcaaag cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct
    14161 gtttttgccc gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc
    14221 aagaatgctc gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat
    14281 agctgcaaaa tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct
    14341 tcccgcgtaa atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga
    14401 ttgctcttgg gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat
    14461 cgtttgtttc cagattgata aactttatct gctagttgca cagcttgatc gccacttaaa
    14521 cgaacgatac tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat
    14581 tctaaagtaa tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc
    14641 ccactccacc ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga
    14701 ttaaattctg gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta
    14761 gatgaagttg agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct
    14821 ttgcgttctt tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta
    14881 aaaaaaacgg tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa
    14941 tatgtgagcc cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat
    15001 gtcgttttat ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt
    15061 gtggaatgct tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta
    15121 acaacgaaga ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac
    15181 tgtcattttg agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct
    15241 tatggaacag tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa
    15301 gcggatcaaa actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt
    15361 catcgtatac tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt
    15421 caacgtgatt tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact
    15481 aaataacgat aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat
    15541 gcagcatgga tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct
    15601 gtccgtttta ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt
    15661 tcacggtaat tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg
    15721 aagacttgtg ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg
    15781 ccttgctttt gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg
    15841 acaagagctg gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt
    15901 aaagctgctt catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg
    15961 ttgactacct cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct
    16021 actgtttcag aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga
    16081 cccattccta ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg
    16141 gccaaaccca aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa
    16201 atcggcatta gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct
    16261 taagagcacg ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt
    16321 tgaaagggtt gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt
    16381 ataatgaaag accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga
    16441 aattcatgat cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac
    16501 ttgcaaaagt aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta
    16561 agttcaacca taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata
    16621 acgccatcaa gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc
    16681 cattttctgc atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc
    16741 ttgaactata ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca
    16801 tgctctttgt ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata
    16861 aaatgatccc tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat
    16921 aaacaatata acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac
    16981 cggataagac gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct
    17041 tcacttactc ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt
    17101 ggagcgaacc tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc
    17161 caactccgga tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac
    17221 ttcattgcgg tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg
    17281 aggctgtccc ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc
    17341 cgtatggaac acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag
    17401 ttttctttcc ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc
    17461 tttcatcatt tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc
    17521 tgaaagaact tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt
    17581 actcatacgt ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt
    17641 tcttttcata tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt
    17701 tgatagtata acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa
    17761 acttatccac aagattattt ttttctatgg gagtcctatg tggaaaaagt tatgcacagg
    17821 gattatccac agataataaa tggctggttt tacacagaaa acacacgtgt aaaaaaagta
    17881 atccacaatc aggtgatttc ctgtgtattc cgtctcctaa ctattggtat atctatattt
    17941 tttatccaca gatgcaagag gaaatctatt gatttttacg agttttccac ctgtgcatta
    18001 gtggtgtgga aaactttttt ttgacaactg tgtttttctc ttttttcttt ttgtcgattg
    18061 tgtggataat tgtaattaaa aaattttttt cttcggtttc tgtggaaaac tattgaaaaa
    18121 aatgctaaat tagtactagt tattcacttt ttaatgaagg aggaggcctt atatggtatc
    18181 cctcgatgct ttatggaatg aattaaaagc aacataccaa aaggatttat cgcctgctag
    18241 ctataataca tggatcgaaa cagcgaaccc tcgaaccctt gatcaaaacc agctcgttgt
    18301 tgaggttcct agcaagattc ataaagaata ttgggaaaaa aacctggcga caaaaatcgt
    18361 tgaagtcggt tatatgttat caggaaatga gattatccct cgctttatta ctggcgaaga
    18421 agcagagcaa gaagaagtta tagaagaaaa aaatccaaaa gttgtggcac ctagtccgct
    18481 aaaaaaagcc atgctgaacc ctaaatatac ctttgatacg tttgtcattg gtaaaggaaa
    18541 ccagatggct catgcagcag cgctcgttgt agcagaagat ccaggttcta tttataaccc
    18601 gctcttcttt tatggaggcg tgggacttgg taagactcac ttgatgcatg caattggtca
    18661 tcaaatgctg caaagtcagc ctaatgccaa agtaaaatat gtaagcagtg aaacttttgc
    18721 taatgatttc atcaattcga tccaaaacaa aacagcagaa gagttccgtc aagaatatcg
    18781 aaatgttgat ttactgctag tggatgacat tcaatttttt gcagaaaaag aagctacgca
    18841 agaagagttt ttccatactt tcaatgcctt gtacaatgaa gggaaacaaa tcgtactaac
    18901 cagtgatcgg ttgccaaacg agattccgaa actgcaagaa cgcctcgttt ctcgctttgc
    18961 atgggggctg tctgttgata ttacaccgcc ggatcttgaa acaagaacag cgattttacg
    19021 taaaaaagcg gcggctgaac gtctagagat cccagatgac acactaagct acatcgcagg
    19081 acaaattgat tctaacattc gtgaattaga aggtgcgctt gttcgagtgc aagcttttgc
    19141 tgcgatgaat agtgaagata tttcgactag tctagctgca gacgcactga aaacgttaaa
    19201 atcaggaaaa ggacatcctc aattgtcaat cctgcagatc caagaagaag tggcaaagta
    19261 ttatcacatc caattgaaag atatcaaagg aaagaaacgc gtcaaatcta ttgttgttcc
    19321 tagacaaatc gctatgtatt tggcacgtga gctcacagat aattctttac cgaaaatcgg
    19381 agctgaattc ggtggcaagg atcatacaac ggttatccat gctcatgaaa aaatccagca
    19441 gctgatggat tctagtgtca gtatgcaaaa tgaagtatca gaaatcaaaa actttttact
    19501 aaattaattt gtcgattcta tcaactgaaa atagcatgtg gataaaagaa aaaaacgttc
    19561 aaaagttatg cacacttttt ccacagctgt tttttcgttt ctctcttacg ttttttgagt
    19621 tttccacaga atcaacatgc cctattactt ttattattct ttttaactaa taataaataa
    19681 acaaacattc aaaggagata catcatgaaa gttactttaa accgagctag ctttatgcag
    19741 gaattgcaaa ctgttcaacg agctatttca agcaaaacca cgatccctat tttgacaggt
    19801 gtaaaaatca cactgacaca agaaggtttg actttgacgg ggagcaacgc tgatatatca
    19861 attgaaactt ttttgtctgt tgaaaacgaa aaagcaaata tgcaaatcga atctactggt
    19921 tccattgttt tacaagcacg tttctttagc gaaatcattc ggagacttcc tgaagaaaca
    19981 tttactttag aagttttaga aaataaacaa gtagcgatta cttctggaaa agcgaatttt
    20041 atcgtaaatg gattagatgc agataactat cctcatcttc ctgttgtcga aagccataac
    20101 cagatgaaat tacctgtaca cgtattgact aaactaatca acgaaacagt ttttgctgtc
    20161 tcacaacatg agagtcgtcc aatcttgaca ggtgtgcatt tcattttatc tgataattct
    20221 ttattggctg tagctactga ttctcaccgt ctaagtcaac gcgtgattcc agtagaacaa
    20281 gcggctgatc attttgatat tgttattcct ggaaaaagtt tgatcgaatt atctcgctca
    20341 ttaacaaatg aagaagaaat cgtcgaaatc agcattatgg aaaaccaagt gttgttcaaa
    20401 acagaaacga tgtatttcta ttcccgtttg ctagaaggaa actatcctga taccaatcgt
    20461 ttgattcctt caagttttaa tacagaggtt gaattttctg ttcctagctt tttagcggcg
    20521 atcgaacggg cttctttact ttctcatgaa ggccgtaaca acatcgttcg tttatctatt
    20581 cgtccagatg cggttgtttt atacggaaat tcgccagaaa tcgggaaagt agaagaaagc
    20641 ttgagttata cagcaagcag tggcgatcca ttagatattt ctttcaatcc ggattatatg
    20701 aaagcagcgt tgcgtgcatt tggagatatg agcatcaaag tgaaatttat ctctgctatt
    20761 cgtccattta cattggaacc aacggaagat ggcgttcaat ttattcagct gattactcct
    20821 gtacgtacaa attaacaatg attttcattg ttcttgaaaa tttaattgaa aagaaataga
    20881 aaaaataaaa ttttaaacag aaggccctaa aatctctttt aaggctttct gtttattttt
    20941 gtttaaatca ccttttttag attaaatcgt cttatatgga aaaatatatg gataaatttg
    21001 ttttattgcg aaaaaaaagg tataatagag tatactttta ataatgaaaa tgagggatgg
    21061 gcattgaaac aacaagtcat tctaaatacg gaattcatga cgttgggcca aatgttgaaa
    21121 gaagtcacag ttatcggtag tggcggacaa gcaaaatggt atttggcaga aaacactgtg
    21181 ttagtcgatg gcgaaccaga aaatcgtcgt ggacgcaaac tttatcccgg catgatggtt
    21241 gaagttccag aagtaggaac tttttttatg gtaaaaaaag gaaacgacga taatgaggct
    21301 gaataagctg tatttaaaaa attatcgaaa ttacgaagag ctgaacatcg aattttccaa
    21361 gaacctcgtc atctttttag gagaaaatgc gcaaggaaaa acgaatcttt tggaaagtat
    21421 ctacgtatta gctatgacgc gaagtcatcg gacaagtagt gagcaggaat tgattggctg
    21481 gactgacgat caggcgatga ttcaaggaga gatcacaaaa ggttcatcca ctcttccatt
    21541 agaaatctta ttatctaaaa aaggccgaaa aaccaagatc aaccatatcg aacaaaaaaa
    21601 gttaagtact tacgtgggac aaatgaatgt cattttattt gcaccagaag atctttcttt
    21661 agtaaaaggc agcccgcaga tcaggcggaa gtttttagat atggaattag gccagatcaa
    21721 tccaatctat ctttatgatc ttgtccaata ccaagcaatt ttgaaacaaa gaaaccagta
    21781 tttaaagcaa ttgaatgaaa aaaaacaaac tgatttgctt tatttggata ttttgtccga
    21841 acaactagca gcgtttggca gcaaagtatt gaaagcaaga gcacagttcg tcaagcgatt
    21901 ggagttttgg gctaattctt tgcatcagca aatcacccat caaaaagagc agctggaaat
    21961 cgagtatctc accgcagtcg attctttaga aacacatacg caagagcaaa tccaagaaca
    22021 atttctcgca cttttgaacc aaaataaaaa gaaagacctt tttcggggaa caacgacagt
    22081 tggtcctcat cgtgacgatc tttccttttt tattaatcag aaaaatgtgc agacttatgg
    22141 atcgcaagga cagcaaagaa caactgcact aagtgtcaaa ttagcagaaa tcgatttgat
    22201 taaagaagag acgggggaat atccaatcct tttgttagat gatgtgatga gcgagctgga
    22261 tgatagtcgt caactccatc tgctagaaac aatcgaagga aaagttcaaa cgttcttaac
    22321 aacaacgaca cttgaccatg taaaaaataa aatgactgtt gaacctgaga ttttttatgt
    22381 tcaacaaggg aaactaaaag gagaagaaac tgaatgacag aagaaagaag tttagtagaa
    22441 cgcgctaaag agtatgatgc cagtcagatt caagtacttg aaggacttga agccgttcgt
    22501 aaacgacctg gcatgtatat cggttcgact agttctgagg gtctgcatca ccttgtttgg
    22561 gaaattgtcg ataattcgat cgatgaagta ttagcaggtt ttgcaacgaa aatccatgtg
    22621 attattgaaa aagacaacag tatcaccgtt attgacgacg gtcgggggat acctgtagat
    22681 atccaggcaa aaactggacg tcctgcagtt gaaacggtct ttactgtttt acatgctgga
    22741 ggaaaattcg gcggtggtgg gtacaaagtt tctggtggac ttcacggagt aggatcttct
    22801 gttgttaacg cgctttctac acagcttgat gtcaaagtat acaaagaagg aaatgtgtac
    22861 tatcaagaat atcgtcgtgg agctgtagtg gacgacttaa agattatcga acaaacggat
    22921 cgccatggaa caacggttca ctttacgcca gaccctgaaa tttttacaga gacaactgag
    22981 tttgattttt caaaattggc tacccggatc cgtgaacttg ctttcttgaa ccgcgggatg
    23041 cgtatatcga ttgaagacaa acgagaagaa gaaccagtca tcaatgaata ccattatgac
    23101 ggcgggatta aaagttatgt cgaatacttg aatgcaaaca aaaccgtgat ttttccagaa
    23161 cctgtatatt tggaaggtga acagcaagat atcgcagttg aagtctctat gcaatataca
    23221 gacggctacc attccaatat catgagtttt gccaacaata tccatacgta tgaaggcgga
    23281 acacatgaat caggattcaa gactgcttta actcgtgtga taaatgatta tgcccgaaaa
    23341 caaaagctga tgaaagaaaa tgacgacaac ttgaccggtg aagacgtgcg agaaggattg
    23401 acagctgtta tttctatcaa gcatcctgac cctcaattcg aaggacaaac aaaaacaaaa
    23461 ttgggcaatt ccgaagtacg gacagtcact gatcggttat ttagcgaaca tttcatgaaa
    23521 ttcttgctgg aaaacccaag tgtgggccgt caaattgttg aaaaaggatt actagcttcc
    23581 agagctcgtc tagcagcgaa acgtgcgcgt gaagtaacga gacgtaaagg tgctttagag
    23641 attagtaatc tgccaggaaa attagcggac tgctctagca acgatcctga aaaatgcgaa
    23701 ttgttcatcg tcgaaggaga ttcggccggc ggatcagcta agcaaggtcg taatcgagag
    23761 tttcaagcca tcttgcctat tcgtgggaaa atcttgaatg ttgaaaaagc aagcatggac
    23821 aagatcttgg caaatgaaga gatccggtct ttatttactg ctatgggtac agggtttgga
    23881 gaagattttg atgtatcgaa agctcgctac cacaaattag ttatcatgac tgatgccgat
    23941 gtcgacggcg cgcatatccg tacattgctg ctgactcttt tttatcgtta catgcgtcct
    24001 attgttgaag ctggatacgt ctatattgct cagccacctt tatacggggt aaaacaaggg
    24061 aagaatatta cgtatgtaca accaggaaaa aatgcagaag aagagttgaa acaagtcgtt
    24121 gcttcacttc ctgcctcacc aaaaccaagc gttcagcgtt ataaaggact tggagaaatg
    24181 gatgatcatc aactatggga aacaactatg gacccaagca atcggatgat ggcccgcgtc
    24241 agtgtggacg atgctattgc agcagatcag atatttgaaa tgttgatggg ggatcgagta
    24301 gaaccccgtc gtgcattcat cgaggaaaat gcacactatg tgaagaactt agatatttaa
    24361 tcatgaagga ggaaaaagaa tgagtgaaga aatcagagaa aacatccatg atgtcaatct
    24421 aaccagcgaa atgaaagact ccttcatcga ttatgcgatg agtgttattg tcgcacgtgc
    24481 acttcctgat gtcagagatg gtctgaaacc cgttcatcgc cgtattttat acggcatgaa
    24541 cgaattaggt gtaacaccgg ataaagccca taaaaaatct gccagaatcg tcggagatgt
    24601 catgggtaaa taccatcctc atggagacta tgcgatctat gagtcaatgg tacggatggc
    24661 acagccattc agctaccgtt atatgctagt ggatggtcat ggaaactttg gttctgttga
    24721 cggtgacggt gccgccgcta tgcgttatac cgaagcacgg atgagcaaaa tcgctacaga
    24781 aatgctgcgt gatatcaata agaacactgt tgatttccaa agcaactatg atgatacaga
    24841 aaaagaacca gttgtactac ctgctcgctt cccgaatctt ttagtgaacg gaacaacggg
    24901 gatcgccgta ggtatggcca cgaatatccc acctcataac ttgtctgagg tagtagcggc
    24961 tatcgatttg ctgatggata atcctgatgt gacgaccaat gaattgatgg aagtattacc
    25021 tggaccagat tttccaacag gtggtttggt tatgggaaaa tcaggaatcc gaagagcgta
    25081 tgaaacaggt aagggttcta ttaccgtacg tgcaaaagtt gagattactg agatgccaaa
    25141 tggtaaagaa cggatcatcg tgacagaatt gccttatatg gtcaataaag caaaattgat
    25201 cgaacggatt tctgaactgc acagagacaa gcgtatcgaa gggatcacag atttgcggga
    25261 cgaatcttcc cgtgaaggta tgcggatcgt cattgacatc cgtcgtgacg ccagcgcatc
    25321 tgttatcttg aataacttat ataaattgac atccttgcaa aattcatttg gattcaatat
    25381 gttggcgatc gaaaaaggtg tgccgaaagt tttgagcttg aaacaaattc ttgaaaacta
    25441 tatcgaacat cagcgcgaag tcatcacaag acggacagtc tttgaaaaag aaaaagcaga
    25501 agcaagggca cacattttag aaggtttgcg tattgctttg gatcatatcg atgaaatcat
    25561 tgcgattatc cgcgggtcta aatcagatga cgaagcaaaa gcgacgatga tcgaacggtt
    25621 cgatttatcc gatcgccagt ctcaagctat tttagatatg cgtttacgcc gattgaccgg
    25681 tttggaacgg gaaaaaatcg aaaatgaata ccaagaactc ttaaaactga ttgaagattt
    25741 aactgacatt ctggcaagac cagaacgtgt tacagaaatc atcaagaatg aattagcaga
    25801 cttgaatcaa cgatttggtg ataaacgacg cacagaatta ctagtcggtg aggtcttaag
    25861 tctggaagat gaagatttaa tcgaagaaga agaaatcgtt attacattga caaacaatgg
    25921 ttacatcaaa cgtttggcaa ataatgaatt cagagctcaa cgaaggggtg gacgtggtgt
    25981 ccaaggaatg ggtatccaca atgacgactt cgtcaaaaat ctggtttctt gttctaccca
    26041 tgatacattg ttattcttta cgaataacgg aaaagtgtat cgggcaaaag gatacgaaat
    26101 tccagaatac gggcgcacag ccaaaggaat accaattatc aatttactag gtatcgattc
    26161 gagtgaaagc atccaggcaa tcattgcggt gacgggagaa gcagaagaag gccactatct
    26221 cttctttacg acgcgtcaag gtacagtaaa acgtacttct gtcactgctt ttgctaacat
    26281 ccgaagtaat ggtctgatcg caattggttt gaaagaagac gatgagctcg tcaatgtgct
    26341 actgacagat ggtcaatcta atatcattat tggaacacat aacggctact ctgtcacttt
    26401 caaagaagaa gcagtccgcg atatgggacg tacagcttcc ggggttagag gaatacgcct
    26461 gcgtgaggaa gattatgtcg ttggggcagc cttaatgaag gaagatcaag aagtattagt
    26521 gatcacagaa aaaggttacg gaaaacggac aaaagtatcg gaatatccag tgaaaggccg
    26581 cggaggtaaa gggatcaaaa cggcgaacat cactgaaaaa aatggtccac tagctggatt
    26641 gaccactgtt tctggagatg aagacatcat gctgattaca gataaaggtg tcattatccg
    26701 tttcaacgta tcgactgttt ctcaaactgg acgttcaaca ttaggcgtac gtttgatgaa
    26761 gatggaagct gatacgaaag ttgtcacgat ggcagcagtc gaaccagaag ctgcagaaca
    26821 aacagttgaa gaacaaggat cagaagaata gccatcaaga ctaattgtgt aagctagcaa
    26881 gaatgaccga ttaaaaaatc tggttattcc tgctggcttt tttgattagt tgaatttctc
    26941 ttaaaatatt cgaaactgtt cattctgtat tgcttttgac caaaatagag tgtataatca
    27001 gagcttgtga gtagtctaat taattagata actctccttg ctcttaggaa cctaagagcc
    27061 gaaagtccac agggaggtga atatcaatgg aaaacacgaa atatgaaatc atgtacatta
    27121 ttcgtccaaa cattgatgaa gaagcaaaaa ctgctttaat cgaacgtttc gatgcaatct
    27181 tgaaagataa cggagcagaa gttatcgaat caaaagattg ggaaaaacgc cgtttcgctt
    27241 atgaaatgaa cggttaccgt gaaggtatct atcacatcgt taaagtatct tctccatcat
    27301 cagcaaatgc tgtcaatgaa tttgaccgtc ttgctaaaat caacgacgat atcattcgtc
    27361 acatgattgt taaagaagaa gcttaattgt tgtttcatgt gaaacaatag aaaacgatga
    27421 gaggagatga ctattttgat taataatgtt gtattagttg gacgtctgac gaaagatcca
    27481 gatttgcgtt acacagcaag tggtacggca gtcgcaacat ttactttggc tgtgaatcgt
    27541 aattttacaa accaaagcgg caatcgcgag gctgatttta tcaactgtgt gatttggcgc
    27601 aaatcagcag aaactttagc aaactatgct cgtaaaggaa cacttttagg tgttactgga
    27661 cgtatccaaa ctcgttctta tgataatcag caaggacaac gtgtatacgt gacagaagta
    27721 gtagctgaca acttccaatt gctggaaagt cgttctgcat ctgaaaatcg ccaacaaagc
    27781 ggcggattcc aaagttctgg tcaatcagct ggcggatttg gcggaaacaa taactctaat
    27841 caaacatctc aatcatccaa cggtatgcct gatttcgacc gtgatacttc tgacccattc
    27901 ggctcaagtt caacgatcga catttcagac gatgatttac cattctaaac gaatttgata
    27961 ggagggaaat agaatggcac aacaaagaag aggcggacgt aaacgtcgta aagtagacta
    28021 cattgctgct aaccatattg aatatatcga ttataaagat atcgaattac taaaaagatt
    28081 tatttcagaa cgcggtaaaa tcttgccacg tcgtgtaact ggtacaggcg ctaaaaacca
    28141 acgtaaaatt actgttgcaa tcaaacgcgc tcgtatcatg ggcttgctac ctttcgttag
    28201 cgaagactaa taaatcctag gaattgaatg actgatcctt ttgatcagct attcaattcc
    28261 tttttttctg taaaaataac ctctattcgt ttagtcgctc gaatgacgaa agttatggta
    28321 aaatcaaatt agtcatatat gggaggaaaa ttatggaaaa taaaaacaat catttatccc
    28381 cgaaacctct cttccttatc ctgtttatat taatcgaagt attggtagtc ttaattttac
    28441 catttcgttt tgttagcgct tcggtcattc tattgatgaa tttatggggt gttcgctatt
    28501 ggttgaaaat gaaacgttgg cttattttaa ataaacgtga aaaaatccag caggcttcga
    28561 ctgtagctga aaccaatcta gcttatgtct cagaagtcat gcctgtagga gtgattgctt
    28621 atcagccatc aagccaaaaa atcgaatggc tcaatccatt agcattgaaa atcaaagatc
    28681 aaagtggatt aacagaggaa gaattgctag atactttttt tactgcaaaa gaaaaaaaga
    28741 aaaaccaagt ctatctagca gataaaacat ttcagtttga tatggataca gtaaagggtg
    28801 ttgtttattt taatgatatt acccaaaacc agttgttaaa actccatcag acgaacagtc
    28861 agccggtgat tggtatttta tctattgata actatgcaga tgccattgat aaattggatg
    28921 acaaagagat ttcttatttg aactctttcg tcactacact agtttctgac tggatgaatg
    28981 aataccatgt ctttttcaaa agaatcaacg cagaacggtt tttcttcgta gcacagatga
    29041 tcgatctgaa aaagatgatg gataaaaaat ttgatttgct ggatcgcttt cgagcagaag
    29101 ctgaaaaaca gagctcgcct atcaccctta gtatggggat tgcttatggc tcaagaaccc
    29161 tcgatgaaat cggtggagaa gctcagaata atttagatgt tgctttagtc cgtggaggcg
    29221 accaagttgt cgtgaaagag gtaaaagaag gagcaaaacc tgtttattat ggggggaaat
    29281 ctgctaagaa tgtcaaacgc acgcgtgttc gttctcgagc gatgagtacc gctttgcgtc
    29341 ggatttttga tgaaacaggc gatgtgttta tcatggggca caagtttccg gatatggatg
    29401 ctttaggctc tgcttttggt gtcagttgtc tggcacgctt caaccagaaa aaagcttaca
    29461 tcgttatcaa cgagaacgag atcattccag atgtagaacg gtgtcttgaa gaaatccata
    29521 agcatcctga attagaaatg caactaatct ctccagaacg tgccatagag ctgaaaaaag
    29581 aagaggacct cctcgtgatg gtggattacc ataaaccttc tctatcgatc tctcagggcc
    29641 tatatgagca atttgataag attgtgatca ttgatcacca tcgtcgtggg gaagagtttc
    29701 caagtaaacc tctgctgact tatatcgaat cttcagcttc ttcagcttca gagctagttt
    29761 ctgagctgat ccaataccaa agcagcaaaa caaatcgctt agatcgtttt gaggccacat
    29821 tattgcttgc agggatggtt gtagatacaa atagtttcaa tgtccgtaca actgcacgaa
    29881 cttttgacgt tgccagctat ttaaggtctt gtggagcaga cgcatcctta gtacaatatt
    29941 tattgagctc ggatttagcg acatacttgg agatcagcaa tttgattgct ggaagcgact
    30001 atgtgacttc tgatattgtt gtggcggcag ggacagacga aaaagagtat aatagtgtta
    30061 tagcagcaaa aacagcagat acattgcttt cgatgatcaa tatcaatgca gctttcgtca
    30121 ttacaaagcg gacagacggc ttgattggga tcagtgccag aagtaccggc acgatcaacg
    30181 tccaaatcat catggaatcc ttaggtggcg gaggacactt cacaaacgca gctactcaac
    30241 tggaaaatac gacagttgag gaaacaaaac agaagctatt tgctgcaatc aaagaaaata
    30301 tgaatcaaat atatgataag gagtaatcca aatgaaagta atttttttac aagatgtaaa
    30361 aggaaaaggt aaaaaagggg acatcaaaga agttccagca ggttatgcac aaaattatct
    30421 aatcaaaaat aacttggcaa aagaagcaac gaaaagcagt atcagtcagt tagcaggaca
    30481 aaagaaagca caagaaaaac acgaagctga aatcttggaa gaagctaaaa agttaaaaga
    30541 attcttggaa aaagaagata ctgtagtcga attgaaggcg aaagcagggg aagacagccg
    30601 tttgtttggt tcgatccctt caaaacaaat tgctgaaggg ttaaacaaac aatacaaaat
    30661 caaattagat aaacgaaaaa tcgaattaga aaatccgatc cgttcactag gctacacaaa
    30721 cgtacctgtt aagcttcatc atgaggtgac ggctacgatc aaagttcatg tcgtacaaga
    30781 ataacaaatc ttgatagcga tgttcagctg gtaagtataa ccagaaggaa aaaagacaaa
    30841 ccgaaattta tctgagaaaa cagctgcagc aatgaaagca aaagctgcaa atcgatttca
    30901 gattgatttc ggtttctttt ttgggaacag caaaatagca taaagaaaac gagtataata
    30961 aaagagaact atttttttat tacactttcg gtacgaatga tgacttttct ctcattttct
    31021 tgtaaaatga agcaattgaa gacaaggagc gatacgtatg aatgaagtgt ggcaggatcg
    31081 aatcccaccg caaaatattg aagctgaaca agcggtttta ggctctgttt ttcttgacgc
    31141 agaaacgatc attgatgcca tggagtacat agagccaaaa gacttttatc gtcgtggcca
    31201 tcaaattatt tttgagacaa tgatcgagtt aaatgatcgt aatgaagcga ttgacgtggt
    31261 tactgtcaaa gaccggctgg aacaagccaa tttgttagaa gatgccggtg gtttaagtta
    31321 tctctcagac ttggcattag cagttccgac agcagcaaat atcgtctact atgcgaaaat
    31381 cgttgaagaa aaatcattgc tgcgtacatt gatccagaca gcaacaggaa tcgttacgaa
    31441 aggattcgag caaggagaag aagttcaaac aattttagat gatgccgaac gcagtatctt
    31501 ggaggtttcg gaaaaaagaa atcgaagcgg ctttttatct attgctgaag tactgaactc
    31561 cacgattgaa aatatcgatc gactagctca aaacaatgaa gaaatcacag gtctaccaac
    31621 tggctatcaa ggtctggata aaatgacagc aggtttccag cccgaagaac taatcattct
    31681 tgctgcacgt ccagcggtag gtaaaacagc gtttgcattg aatattgctc aaaatgtagg
    31741 aacaaaaaca gatcgttctg ttgcgatatt tagtttggaa atgggggcag aatctcttgt
    31801 aaatcggatg ctttgtgcag aaggttcgat tgaggccagc catttacgta caggtcagct
    31861 ttcggaagaa gaatggtcga atctgatcgt tgcgatgggg agtctttctc gagcaaatat
    31921 ttttatcgat gatacaccag ggatcaaaat ctctgaaatc cgtgcgaaat gtcggaaact
    31981 agcgcaagaa aaaggcaatc taggcttgat attgatcgat tatttgcagt tgattgaagg
    32041 taacggtaaa gagaaccgtc aacaagaagt atcagatatc tctcgccaac tgaaaaaact
    32101 ggcgaaagag ctgaaagtac ctgtcattgc tctttcacag ttatctcgtg gagtagaaca
    32161 gcgacaagac aaacgaccag tgctaagtga tattcgtgaa tccggatcaa ttgaacaaga
    32221 tgcggacatc gtagccttct tgtatcgaga tgattattat gaaagagaag gcggagatga
    32281 cgatgatgga aacgagccaa aaaatgacaa cgtcatcgaa gtcatcatcg agaagaaccg
    32341 aagcggtgca cgaggaacag ttgaactact gtttatcaaa gaatacaata agttttcgtc
    32401 gctttcgcca agagaagaat tttaaagaag aggttgtgag ccttgagcaa tcccgagagc
    32461 tctcgtaaga agatgcaagg agtaaccgca ggaacgacta gagtacttaa tttaaacaga
    32521 tctccaaagg gattgtgaca aaagtcttgt cacagtccct ttttccgaat aaacggtgtt
    32581 caatcagctg acccttggta ttagctcagc aaacgtcaaa atatgaggaa ctattttgac
    32641 gtttgtttct ctaatactca ggtcaaaacg ctgatcttac gacctctttt ccttaaacgg
    32701 tgttctcctg ccaactcctc ggtcacaagt cacaatatca tcaaacatga gaagcagttt
    32761 tttgaaattg ctccttgtga ctcagagtta aacggcaggc tcacaacctc tttcttaaac
    32821 ggtgttcaaa agcttgcatc tgcggtaata cgcccaatca aacgaaaaat atgagaagct
    32881 atttttgttt ggctgttctt attacttgat gcaggacagc tttttcacaa cctctgattc
    32941 acggtgttcc aaaagtagct tcttcgaaaa ataagtcgaa atttcacaaa aatttgagaa
    33001 gcaattttcg tacattcctt cttatttctt gaagctgacc acttctgtta caacctcttt
    33061 tttaataacc attctaaaaa gataaagttc gttttttaag cgtttttata aaataaaaat
    33121 aaaaatcatt cgattttatt tgaaatatgt atctattatt gatacaatgg ttcaggatta
    33181 aataatatag aacgaggtgt tcacatgtca tctgtagtag tagtaggtac gcaatggggc
    33241 gatgaaggga aaggaaaaat cacagacttt ctcagtgaaa atgctgaagt gattgcacgg
    33301 taccaaggtg gcgacaatgc agggcacaca attaagttta acggtgtgac ttataaactg
    33361 catttgattc cttctgggat tttttataaa gacaagatca gtgtgatcgg aaacggcgtt
    33421 gtagtcaatc ctaaatcatt ggttaaagaa ttagcttatt tacatgaaaa aggtgtagaa
    33481 acaagtaatt tgcgtatttc tgaccgcgcg cacgtaatct tgccttatca tatcaaattg
    33541 gaccaattac aagaagatgc taagggcgaa aataagattg gtacaacgat taaaggaatc
    33601 ggacctgcct atatggataa agcagctcgt gtaggtatcc gtattgcaga cttattagat
    33661 aaagaaattt ttgaagaacg tcttcgtttg aatctagatg acaaaaaccg tcaatttgta
    33721 aaaatgtttg attcagaacc acttgatttt gacgatattt ttgaagaata ttatgaatac
    33781 ggacaacaaa tcaaacaata cgtcacagat acttccgtta tcttgaatga tgctttggat
    33841 gcaggcaaac gcgtgttgtt tgaaggcgca caaggtgtaa tgctggatat cgaccaggga
    33901 acttatcctt ttgttacttc ttctaaccca gtagccggtg gggtaacaat cggaagcggt
    33961 gtagggcctt caaaaatcaa taaagttgtc ggcgtctgca aagcctatac gtcacgtgtc
    34021 ggtgatggac catttccaac tgaattattt gatgaaacag gagaacaaat ccgcgaagta
    34081 ggacgagaat acggtacgac aactggtcgt ccgcgtcgtg taggctggtt tgattctgta
    34141 gttatgcgcc attctaaacg agtttcaggt attaccaacc tatctttaaa ctcgatcgat
    34201 gtattaagtg gattggaaac agtaaaaatt tgtacggctt atgaattaga tggcgaacta
    34261 atctaccact atccagcaag cttgaaagag ttgaaccgct gcaaaccaat ctatgaagaa
    34321 ttgccaggct ggtcagaaga cattacagga tgcaaaacac ttgcagaact gccagaaaac
    34381 gcacgtaact atgtacgtcg tatctcagag cttgttggtg tacgtatctc aacattttct
    34441 gtcggacctg atagaacaca aacaaacatc ttagaaagcg tctgggcgca aatctaagga
    34501 taaaaacgac gactgaatca ggacgttctt accagagcga gtcgaagtgt ttatctatac
    34561 gataataata acttgaagag gtagtgaaag agacgtttag ccttattgcc gataggctgt
    34621 ctcttgaaca ctgtttattc agaataaggg actgtgacaa aaaccgtgtc acagtccctt
    34681 tttccgaa
//
LOCUS       DADGKS010000023        33859 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.023, whole genome shotgun sequence.
ACCESSION   DADGKS010000023 DADGKS010000000
VERSION     DADGKS010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33859
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.023"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(116..673)
                     /gene="frr"
                     /locus_tag="JXV47_001240"
     CDS             complement(116..673)
                     /gene="frr"
                     /locus_tag="JXV47_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HAX1487294.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(676..1398)
                     /locus_tag="JXV47_001241"
     CDS             complement(676..1398)
                     /locus_tag="JXV47_001241"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010761216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HAX1487295.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1534..2415)
                     /locus_tag="JXV47_001242"
     CDS             complement(1534..2415)
                     /locus_tag="JXV47_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HAX1487296.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2514..3296)
                     /gene="rpsB"
                     /locus_tag="JXV47_001243"
     CDS             complement(2514..3296)
                     /gene="rpsB"
                     /locus_tag="JXV47_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HAX1487297.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3655..4134
                     /locus_tag="JXV47_001244"
     CDS             3655..4134
                     /locus_tag="JXV47_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HAX1487298.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4351..5442
                     /gene="phnW"
                     /locus_tag="JXV47_001245"
     CDS             4351..5442
                     /gene="phnW"
                     /locus_tag="JXV47_001245"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HAX1487299.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5435..5563
                     /locus_tag="JXV47_001246"
     CDS             5435..5563
                     /locus_tag="JXV47_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HAX1487300.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            5567..6112
                     /locus_tag="JXV47_001247"
     CDS             5567..6112
                     /locus_tag="JXV47_001247"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HAX1487301.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6566..8257)
                     /locus_tag="JXV47_001248"
     CDS             complement(6566..8257)
                     /locus_tag="JXV47_001248"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HAX1487302.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(8677..9624)
                     /gene="arcC"
                     /locus_tag="JXV47_001249"
     CDS             complement(8677..9624)
                     /gene="arcC"
                     /locus_tag="JXV47_001249"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HAX1487303.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(9739..10758)
                     /gene="argF"
                     /locus_tag="JXV47_001250"
     CDS             complement(9739..10758)
                     /gene="argF"
                     /locus_tag="JXV47_001250"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HAX1487304.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(10849..12078)
                     /gene="arcA"
                     /locus_tag="JXV47_001251"
     CDS             complement(10849..12078)
                     /gene="arcA"
                     /locus_tag="JXV47_001251"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HAX1487305.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            12539..13240
                     /locus_tag="JXV47_001252"
     CDS             12539..13240
                     /locus_tag="JXV47_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAX1487306.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(13849..14865)
                     /gene="tsaD"
                     /locus_tag="JXV47_001253"
     CDS             complement(13849..14865)
                     /gene="tsaD"
                     /locus_tag="JXV47_001253"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HAX1487307.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(14862..15326)
                     /gene="rimI"
                     /locus_tag="JXV47_001254"
     CDS             complement(14862..15326)
                     /gene="rimI"
                     /locus_tag="JXV47_001254"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAX1487308.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(15333..15875)
                     /gene="rimI"
                     /locus_tag="JXV47_001255"
     CDS             complement(15333..15875)
                     /gene="rimI"
                     /locus_tag="JXV47_001255"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAX1487309.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(15859..16683)
                     /gene="tsaB"
                     /locus_tag="JXV47_001256"
     CDS             complement(15859..16683)
                     /gene="tsaB"
                     /locus_tag="JXV47_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HAX1487310.1"
                     /translation="MYYCTSFAFGIFILRIKKYATMEGENVIAERIKYMITLGIDTAN
                     QTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAIDQLFADLQISPKDIDRIAVSDGPGS
                     YTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAANCIGVDNIIVPMFDARRKNVYAGAY
                     RWKENRLETVLEDVHISASDLFTQLQKLNEAIYFVGSDCHKFFSEIKEILPSAMINTV
                     PAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKRVEAEEKWLETHTPGDESYVEKI"
     gene            complement(16772..17752)
                     /locus_tag="JXV47_001257"
     CDS             complement(16772..17752)
                     /locus_tag="JXV47_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAX1487311.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(17776..19260)
                     /gene="galT"
                     /locus_tag="JXV47_001258"
     CDS             complement(17776..19260)
                     /gene="galT"
                     /locus_tag="JXV47_001258"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HAX1487312.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(19272..20261)
                     /gene="galE"
                     /locus_tag="JXV47_001259"
     CDS             complement(19272..20261)
                     /gene="galE"
                     /locus_tag="JXV47_001259"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HAX1487313.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            20509..20676
                     /locus_tag="JXV47_001260"
     CDS             20509..20676
                     /locus_tag="JXV47_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HAX1487314.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(20738..22549)
                     /locus_tag="JXV47_001261"
     CDS             complement(20738..22549)
                     /locus_tag="JXV47_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HAX1487315.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(22546..22911)
                     /locus_tag="JXV47_001262"
     CDS             complement(22546..22911)
                     /locus_tag="JXV47_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HAX1487316.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(23074..23469)
                     /locus_tag="JXV47_001263"
     CDS             complement(23074..23469)
                     /locus_tag="JXV47_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAX1487317.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(23487..24449)
                     /locus_tag="JXV47_001264"
     CDS             complement(23487..24449)
                     /locus_tag="JXV47_001264"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HAX1487318.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(24449..24661)
                     /locus_tag="JXV47_001265"
     CDS             complement(24449..24661)
                     /locus_tag="JXV47_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HAX1487319.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(24682..25380)
                     /locus_tag="JXV47_001266"
     CDS             complement(24682..25380)
                     /locus_tag="JXV47_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HAX1487320.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(25400..25942)
                     /locus_tag="JXV47_001267"
     CDS             complement(25400..25942)
                     /locus_tag="JXV47_001267"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HAX1487321.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(26074..27078)
                     /locus_tag="JXV47_001268"
     CDS             complement(26074..27078)
                     /locus_tag="JXV47_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAX1487322.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(27075..28064)
                     /locus_tag="JXV47_001269"
     CDS             complement(27075..28064)
                     /locus_tag="JXV47_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAX1487323.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVEKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(28061..28867)
                     /locus_tag="JXV47_001270"
     CDS             complement(28061..28867)
                     /locus_tag="JXV47_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1487324.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            29033..29989
                     /locus_tag="JXV47_001271"
     CDS             29033..29989
                     /locus_tag="JXV47_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAX1487325.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(30066..30584)
                     /locus_tag="JXV47_001272"
     CDS             complement(30066..30584)
                     /locus_tag="JXV47_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAX1487326.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(30672..30821)
                     /gene="rpmG"
                     /locus_tag="JXV47_001273"
     CDS             complement(30672..30821)
                     /gene="rpmG"
                     /locus_tag="JXV47_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAX1487327.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            31049..31495
                     /locus_tag="JXV47_001274"
     CDS             31049..31495
                     /locus_tag="JXV47_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAX1487328.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(31690..33585)
                     /gene="asnB"
                     /locus_tag="JXV47_001275"
     CDS             complement(31690..33585)
                     /gene="asnB"
                     /locus_tag="JXV47_001275"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HAX1487329.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT         9871 a         7099 c         5916 g        10973 t
ORIGIN      
        1 ttgttttttt atttaaaaac tgaataattt tttctttttt taatttttaa ataaaagaaa
       61 tataaataaa aacagaggaa gcggaatgat ccgcccctct gtttttatga ttttattaaa
      121 cttccaataa ttctttttct ttatcagcag cgatcttatc tacttctttg atgctgttat
      181 ctgtcaatgt ttgtacgtct ttttctaatc cgcgcaaatc atcttcggta atatcaccat
      241 ttttttgttg ttttttatat tcatcgatcg catcacgacg gatgttacga atcgcgattt
      301 ttgcattttc tgcttctttt ttaacatctt tagctaattc ttttctgcgt tcttctgtca
      361 gttgcgggat aactaagcga atgacatttc catcattggt tggactgatt ccgatatcac
      421 ttgccataat agctttttca acatcttgaa gaatgctctt gtcaaaaggt gtgatcatta
      481 aaacacgtgc ttctggaatt tggattgatg ccatttggtt caatggtgtt ggcgcaccgt
      541 agtagttcac agtaatacgg tccaaaaggc tagcgttcgc acggcctgcg cggatttgcc
      601 caagttcacg ttgaagattt tgtgctgctt ttttcatttt ttcttttgct tctgtcataa
      661 ttgcatctgc catttttatt tcccccttac agttgttccg atattttcgc ctaagattgc
      721 acggcgaata tttccgtgtt catttaaatt gaagacaagc agtggaatat cattatccat
      781 gcttagtgaa cttgcagttg aatccatgac ttgtaatcct ttggcaataa cttccagatg
      841 agtcagttct tcaaatttta ctgcatttgc atctactttc ggatcagcag aataaacacc
      901 gtctacattg tttttagcca tcaggataac atctgcgccg atttctgccg cgcgtaatgc
      961 tgctgttgtg tctgtcgaga agtacgggtt gccggtaccg cctgcaaaga taacgatccg
     1021 tcctttttct aaatgacgtt ctgctttacg gcgaatatat ggctctgcga tttgacgcat
     1081 ttcaatcgaa gtttgcacgc gtgtcggtac acccacgttt tccaacgtat cctgtaaagc
     1141 taaggcattc ataactgtag ctaacatacc catgtaatca gcttgagcac gttccatgcc
     1201 catttgtgct ccgatttgtc cgcgccagat atttccgccg cccacaacga ttgccatttc
     1261 aacgcccagc tcgtgaactt ctttgatttc ttggatgatt tctttgatta ctggtggttt
     1321 gattccaaat cctgcgtccc cagctaaagc ttctccactc aattttaaga ctacacgctg
     1381 atatttcggt gtgaccatgt tcattcctcc aatattttct attgccattt taccatactt
     1441 agatgatttc gacactctaa gactggtttt tcttgttttg cttaaaaaaa gggagcgcac
     1501 aaaccgtgcg ttcccgtctg ttattcaaca gaattatttt ttcacttggc tcataacttc
     1561 ttctacaaag ttatcttcgc gtttttcgat accttcgcca acttcgaaac gtacgaatgt
     1621 tttaacagtt gcgccttttg atgcaacgta tttttcaaca gtcatatcag gatctttaac
     1681 gaatggttgg tccaccaaag cgatttctgc tttgaatttc ttcaagcgtc cttctaccat
     1741 tttttcaacg atattcgctg gtttgccttc gttcaatgct tgttctgtaa gaacagtttt
     1801 ttcatgttct aattcagctt ctggaatttg tgattcgttt acataacgag gattgatagc
     1861 tgctacgtgc atagctacgt ctcttgcaac tgtttcgtca gttgttccat ctagaacagt
     1921 caatacggca atacgtccgc ccatatgcaa gtatccacca aatgcagcat tgtcgtcttt
     1981 ttctacaact tcaaagcgac ggaagctgat tttttctccg ataacttgag ttgcttcgat
     2041 caagtcagat tcaattgtac ctttatctgt tttgattttc attgcagctt ccatgtctgc
     2101 tggtttgttt tcagcaacaa gttctgcaat ttcttttact aaatcttgga acatttcgtt
     2161 tttagaaaca aagtctgttt ctgagtttac ttcaacgatt gctgcagtgt tacctttcac
     2221 agcaactgaa gccaatcctt cagctgcaat gcggtcattt ttcttcgcag cctttgccat
     2281 tcctttttca cgtaaaagat caactgcttt ttccatgtcg ccttctactt caactaatgc
     2341 ttttttcgca tccatcattc ctacgccagt catttcgcgt agttctttta ccattttagc
     2401 tgtaacgtct gccatgttta actcctcctg tgtgtttttc tttttaaaaa aagctgcttc
     2461 aaaggagagt gaggcttgtc gcccagcctt tgaaacagct ccatcattca aaattattct
     2521 gctgaagaat tgtcgccttc aacaacatct acgatttctt cgattgatgt tgctgtgttt
     2581 tcttctgtga aatcttcttc aactacttga tcttcacctt ggtttccttc gatgaaagca
     2641 tcagccattt ttgaagtaat caatttaacg gcacgaattg catcgtcgtt tgaagggatt
     2701 actacgtcga tttcatctgg atcgcagttt gtatcaacca tagctacgat tgggatattt
     2761 aatttgtgtg cttcttgaac agcaatacgt tctttacgtg ggtcaacgat gtacattaca
     2821 tctgggattc ttggcatatc agcgataccg cctaagaatt tttcaagacg ttcacgttct
     2881 ttgttcaaac cagcaacttc ttttttaggt agaacttcaa aagttccatc ttcttccatt
     2941 gcattgattt gtttcaaacg gctgatacgt ttttggatag tatcccagtt tgtcaatgtt
     3001 ccgcctaacc aacgatggtt aacgaagtat tgtcctgcac gagttgcttc ttctttgatt
     3061 gcttcttgtg cttgtttttt tgtacctacg aataatgcta cgccgccttc ttcagcaacg
     3121 ctcttcatgt aatcataagc tgcatctact aatttaactg ttttttgcaa gtcaatgatg
     3181 tagattccgt ttctttctgt gaagatatat ttcttcattt ttggattcca gcgacgagtt
     3241 tggtgaccaa agtgtacgcc ggcttctagt aattgtttca tagaaattac tgccatgttt
     3301 gtttcctccg atttggtttt atttttcctc ttcttatctt ctaccttgcc ggcaaacttt
     3361 ttcaagcacc taccgacaat ccaataagaa tgtggatttg ctgatgcata aagcaccctc
     3421 agctattata cagacaaaag atccgtatcg caagagcaaa tatacttttc tgctcaacat
     3481 tcaatagttt acctgaaaga taaaaagaat tcaagaaaaa cagtagattt ctctttgttt
     3541 ctttattatc ctttttccat aaaataattt taggtataaa agacgaatat tattgggcaa
     3601 tccttctttt ttttgttatg atacatgtga aatctttcgt aaaggagaaa gaaaatgcgc
     3661 aaagctcaaa gacatttgct gattaaacaa gtcattgaag aattcccgat ccgtacgcaa
     3721 gaagaactat taaacaaact tgggcattat ggcgttaccg ccacgcaggc aacgatttct
     3781 cgagatatcc gtgatctaaa aatcgtgaag gcacctgatg aaaatggcgt ttcccgcttc
     3841 gtattgtttc gcgaaaaagg aactcctgag actaggactg aggaagagga tcggctggtt
     3901 caaatgattg aagacattgt attgaaagtc gaacgagtcc actttttgac gatcgtcaat
     3961 accttgccag acaatgctca tttatttgca tctgttttag atgagatcaa acctccctct
     4021 attgtcagta caattgctgg attcgatacg atcatggtca tctcggaaaa tgaggaggac
     4081 gcaaaacgag tagaagaatt tcttcaccat ccaactgaag tatcactttt ttaatcagag
     4141 cacgtattcc taatatggaa tgcgtgtttt tttattttca atattttcct tattgaataa
     4201 acctttacac tctttacaaa aatacatcat tttttattca aatttttcaa caccttgatt
     4261 gaatcacaat aatcatcatt tatattggat gttaacaaga gcagcttctt gctctttgtg
     4321 tatttcaaaa aagaaatgaa aggaaatcat atgtataaat tattaacttc tggaccattg
     4381 acgacttctg aaacagtgaa aaatgctatg ctgatcgatc attgtacttg ggatcaagaa
     4441 tacaaagaaa ttacacaatg gataagaaaa aaattattgg atcttgctca agtatcggaa
     4501 ggaatataca caacggtctt aatgcaaggt agcagctcct tcggggtaga atcggtatta
     4561 agttctgtga tcaggccaga agatactgta ctgatttgtt caaacggcgc atatagacaa
     4621 cgaatgatca acatgtgcga atgtctgaaa ctgaactata ccgtttatga ggtatcggaa
     4681 catcaaatcc tccaagctca tgtgattaca cagctgattg aagagaatcc gtctatctcc
     4741 gcactagcaa tggtccatag cgagactact tccggtattt tgaataattt ggaagagatt
     4801 gctgctgtca cacaagaaag agatcttttg tttatagtgg acgcgatgtc aagctttggt
     4861 gggataccga tttgtgtagc cgaactaggg attgattttt tgatttccag ctcaaacaaa
     4921 tgtattcaag gtgttccagg cttttctttt gtacttgcta ataaagcgga actggaaaaa
     4981 cgaaaaaatg ttagccgaag tttgtcactt gatctatatg accagtaccg cgtgatggaa
     5041 aacgagaatg gcaaatggcg tttcacttcc cctacccata cggttttggc ttttcaacaa
     5101 gcgctgaagg aactagaggc agaaggagga atcgaaactc gatattcacg ttatctcgcc
     5161 aataatcatg tgctacgaca aaaaatgaca gagatggggt tccagccttt cattcaagaa
     5221 tatcaggggc cattcatcac ctcttttctt taccctaagg actggcgatt tgattttaat
     5281 catttttatc agtatttaaa gcaaaatgga tttgtgatct atcccgggaa aatcagcgat
     5341 catgaatgtt ttcgtatcgg aaatattggc gagatctatc cggaagatat tttggaactg
     5401 acagcaatta tcaaagacta taaggagaac gttaatgatt aaaactgtaa tttttgattg
     5461 ggcaggaaca actgtggact ttggctgtat ggctcctgtc cacgctttta gaaatgcttt
     5521 tctagaaaaa ggaatccaac tgactgacaa agaaatccgc taaccgatgg gaaaattaaa
     5581 atgggatcat atccaacagc ttctttccct cccttctgtc aaaaaacaat ggatagctat
     5641 ttatggacaa ctacctcagg aaaaagaggt ggaggaattg tatcaacaat ttgaacatta
     5701 tctgtttaaa gatttggtca agcattctac cttgaaaccc gacacattgg aaacgatcga
     5761 acggttgaga aacgctggga tcaatattgg ttccacgaat ggatttaatg ctcctatgat
     5821 gacaatcgta gcagaaaccg caaaaaaaga aaggtattca ccagacttca tggcaacttt
     5881 tgaagacgtc gaagggtatg gtcgaccgtt tccttatatg atccataaaa acatgcagta
     5941 cttcaaaaac aagtcggttg atgaagtaat caaagtcgga gatacggtct cagatatcca
     6001 ggaagggaaa aatgccggag tgttgacagt aggtgtaatt gaaggtagtt cgctaatggg
     6061 gatttcttat gatgagtacc aaaaattaga gatggggaaa aagatcgttt aaaacagtct
     6121 gttgctctta gattccaaca agccggcgct gatatttgtg taaacaattt aaaagagtta
     6181 acagaataca ttttgtacgc tgacatgaat ccagaatgac ttttatacaa aataagaggt
     6241 tgtgaaaaag ctgtcctgta tcaagtaata aaaacagcca agcaaaaata gctcctcata
     6301 tttttcgttt ggttaggctt attaccgcag atgcaagctt ttgaacaccg tttattcgaa
     6361 aaaaaaaagg gagctgtgac acgacttttg tcacagtccc cttatttgca aacaaacagt
     6421 gtttaagaga caacctctcc actaaacggt gttcattcag ctgactctcg gtatttgctc
     6481 aaaaaacgat aaaatttgaa aagctatttt ctcttttgtt tctctaatac tcggatcaga
     6541 acgctgattt cacattctct ttttcttaca tcttatctgg tgcatgaagt cctagcaaac
     6601 gaaggtcttc tttcaataat acagtcactg cataaactag agctaagcgt gcttcttttt
     6661 gttcatcatc agctaaaatc ttcgtatgag catagtattt gttgaatgct tgtgctaatt
     6721 tgattgcatg tttcgcaatc actgacggtt cgtatttttc cccagcagac aagaccgttt
     6781 cagggtattt ttgaactaat ttaaccactt cccagctggt atcgtcattc aatgcatagt
     6841 ctgctgtttc tgaagggaca aatcctgctt tttccaacag gctgactgca cgagcatgtg
     6901 tatattgcac ataaggtcca gtttctcctt caaatcgaac aacttcttcc aggttaaagt
     6961 caaatgtatt cagtcgatcg tttttcaaat cgtggaaaat gactgcccca accccaactt
     7021 gtttagctac agcatctttg ttttccaaat cagggttttt ctcgctgatt tgttctttag
     7081 cagattggat tgcttcattt aatacttctt ctaataagac gatctttcct ttacgagttg
     7141 ataatttttt accaccttgc gtgatcaaac caaatggaat atggtgcatg tcgtcagacc
     7201 agtcaaagcc catttccttc aagacagctt tcaactgttt aaaatgatag ctttgttcat
     7261 tccctactac atatagagat tgtttgaagt cgtaagtacg tttacggtac aatgcagcag
     7321 ctaagtcacg tgtaatgtat agtgtcgcac cgtctgactt cttaatcaac gctggattca
     7381 ggtcataagc agataggtca acgatctctg cacctttatc ctcgttcagc aaatgttttt
     7441 cttctaaaag tttgacgatt tcatccatct tgtcattgta gaaagcttca ccgttcaacg
     7501 aatcgaaacg tacttccagc agatcataga ttttattgaa ttctttcatc gattcatcac
     7561 ggaaccattg ccataattga atagcctctt tatcgccttc ttccagacgt ttgaaccaag
     7621 cacgagcttc ttcatttaat tctggttctg tttcagctac ttcatggaat tggacgtata
     7681 aacgaagcaa ttcattgatt ggttctgctt taacagcttc ttctgtaccc cattttttgt
     7741 aagcgacgat cagttttcca aactgtgttc cccagtcacc taaatggttg atgcggattg
     7801 gctgataacc gattttttcc ataatgaaac cgatcgaatt accgataact gtcgaacgca
     7861 aatgtcccat tgagattggt ttggcaatat taggagaaga catgtcgatt ggtactgttc
     7921 cttgattccc gatgttgcta tccccataat gttctttttc tttcactact gtttgcaaaa
     7981 cttttttgct gataagttct ttattcatga aaaagttcaa gtaaggtccg acaacttcga
     8041 ttttttcaaa gttggcagaa tcgatttttt ctgctaaatc tgcagcgatt tgctgtggcg
     8101 cttttcggta aacttttgct aatgaaaagg ctggaaatgc aacatctccg tgttcagctg
     8161 attttggatt ttctagtaat tgctcgactt gttccagtgt taaatcatct ttgacagcgt
     8221 catagacagc ttttgcgaca agatctttat tattcatctt tattcctcct aaagtgttcc
     8281 cttgattgtt aaacaaaaaa aatctctagc gacggcatac ttagtatgcc atcactagag
     8341 acgagatttc ccgcggtacc actccaattg tcctaaaaaa ggaccagctc catctgatat
     8401 cggtagacga ccgtctgttt aaaacagaat tctccaagtg cgcttcgttg tatcttcttc
     8461 attcggcttc caccacttcc gaattcgcta gccaagaatg atacaagtac tctcttgttc
     8521 aacaaatctt agtcttatta aactttcttg aattatatca gaaaaaaaaa cgaaaggcta
     8581 gtcgtttcat aaaaaaacaa tccagatggc ctaaaggaga agaaatacca cctggatagc
     8641 tataaatcat ttcgtaaata cgaaagactt aacaaattaa tcagctacga taatcgttcc
     8701 ttcttcagaa gctaaaagat tctcgatatt ttctaaagaa gtgatgattg ccttagcgtt
     8761 tggttttgct tcaacaaatg caatagctgc ttctactttc ggaagcatgc ttcctggagc
     8821 gaattgcttt tcatcaatgt attgtttcat ttctgaaaca gtaacagttt ctaatttctt
     8881 ttgatctggt ttttggtaat tgacatacac attgtctact cctgtcaata cgatcagcaa
     8941 atccgcatcg atgatttcgg ctaatttttc tgaagcaaaa tctttatcga ttacggcttc
     9001 tcgtccttct aatccagtag ctgtttctac aacaggaatc ccaccgccac caacagagac
     9061 tgtgataact ccttgatcga ccagcgtttc gatgacacgt gcttctttaa tcgagatggg
     9121 tttaggggaa gcgactactt ttctccatcc acgtccagca tcttctttga atgtcacagt
     9181 ggagtcagca ttcatttgtt ctttggcttc ttcttccgtg tagaatggac cgactggttt
     9241 acttggattt ttgaatgaag gatcattttc atccacaata acttgagtga ctaaagaaac
     9301 cacatcttta tcgatccctt tttccttcag tacttcgccc atggcgtttt gtaaccagta
     9361 accgatagat ccttctgtca ttgcaacaca tgtatctaaa ggcattgccg gtgttttctc
     9421 agaatcagca gcttgctgct gaatcaatag gttaccgact tgcggaccat ttccgtggga
     9481 gatgatcaat tcatctcctt gttcgataaa tttcactaaa tactttgctg tttccattaa
     9541 cgcttcttgt tgggcttttg cacttgcatc cgtagacaag atggcattgc cccctaaagc
     9601 gacaactact tttcgtttgg ccatttcatt cgtcctttct tcagttctac cgaattttct
     9661 agataacaaa acgagccagc gttttgtgat tttccctcaa tgctgactcg ttttttcgtg
     9721 agatgaatgt ggttatgctt aaacgcgagg gataaacaag ttacctaatg ttgctgccat
     9781 gatcgctttg attgagtgca tacgattttc tgcttggtca aattgacgag catatttgct
     9841 gcggaagact tcatctgtta cttccatttc agtgatgcca aagcgttctt tcatttgttc
     9901 accgtaaaca gtgtttgtat catggaaagc tggcaagcag tgcaagaaga tcaaacgatc
     9961 tgtgttgtgt gttttttcta ccatttccat attgatttgg taaggtttca acaatttgat
    10021 acgttcttcg aatttatctt cttcacccat tgatacccat acatcagaat aaaggacgtc
    10081 tgctccgtct acacctttat caacatcgtc ggtaatcatc aattgtgcac cggatttttc
    10141 agcaaagcct tctgccattt tgacgatttc ttcttcaggt tgtaattctt ttggtgcaac
    10201 gatacgcata ttcgctccta aaattgcacc tgtgactaat aaagagttag ccatattgtt
    10261 tcgaccatct ccgcagtaag caacagtgat accttctact gttccaaagt tttcttggat
    10321 agttaaaaag tcagcgatca tttgtgttgg atgccattca tcagtcaagc cattccaaac
    10381 tggaacacca gagaattctg ctagttcctc taccattttt tgactgaatc cacggaattc
    10441 gattccgtca aacatacgtc ctagtacttt agctgtatct tctgtggatt cttttttacc
    10501 taattggata tcatttgcac ctagatattc aggatgtgca cctagatcga tcgctgcagt
    10561 agtaaatgca gaacgagtac gtgtagatgt tttttcaaat aaaagcgcaa tattttttcc
    10621 ttctagatag tgatgtggga taccacgttt tttcaagtct ttcaagtgtt ctgaaaaatc
    10681 gatcaaatat tgtaattctt cttttgtaaa gtctttttct gctaataagc ttcttccttg
    10741 gaatactgat tctttcatat taaacattct cctttagatt gtttttattt aagattaaag
    10801 aggaaatccc gacggcagct gacagtaaga ctgccgtcag gaaacaaatt acttcaagtc
    10861 ttcacggaca agtggttggc tcatgcagcg tggaccacca cgacctcgtg acaattcact
    10921 tgaattgatt tctaacactt tgatgccata gctacgaagc aattcgttcg atacataatt
    10981 tcggttataa gtgactacaa cacctggagc gattgccaat gtgtttgatc catcattcca
    11041 ttgttctcga ggtgcaacga tctcatctcc attaccagtt gggatcagta caagatcatc
    11101 taatccaaga gcagctttca tcgtttcgtg taagttatct gaatgagtaa tcttgatatc
    11161 atcaccatct ggttcgattg taaagacatc catcttaccg tctttacttt gaattgctgg
    11221 atggatagtg aatttatcgt gatctaccat tgtaaatacg gtatccaaat gcatcattgc
    11281 acggttgttc ggaattttga ttgccaacac tttttcaaat cctgaatttt ttgcgaatag
    11341 gtggcgtgct aatttttcta aagctttcgc attagttcgt tgagaaatcc caacagctac
    11401 tactttatcg cttaagatca attcgtctcc gccttcgata tgatctggat tttcacgatc
    11461 caaccatact tcgattcctt tatttgcaaa tcttggatga tgtttcaaaa tatattctgt
    11521 aaacatcgat tcacgacgac gtgcttcaaa agtcatctta ttgactgtca tcccatttcc
    11581 cattgatgcg gaagggtcgc gtgtaaagta caagtttggc attgggtcca tgtaaaatgg
    11641 atagtcatcg tctgctgaca gatcatatag actgctagaa cgtacttcga tatcttttgt
    11701 acgaacccca gccatgattt tatctaccat ttcttgcgtt tccattgata gaaggaactc
    11761 atgaagaccc tctcttacag cattcgatgc aatatgagat tcatccaaca ttttattcaa
    11821 gaattgttct ttgacattgc ctgcgtcaat cgcttctgcc gctaattttt ccaagtaaag
    11881 agtctcgacg ccttcatttt gcaatgtctt cgcaaagttg tcatgttctt cttgagcaat
    11941 cggaagatat ggaatatcat cgaacaacag acgatccata atatctggtg tcaaattttc
    12001 cacttcttgt ccaggccgtt tcagtaaaac tgtctttaat ttccctattt cagagaaaac
    12061 gtgaataggt ttatccatgt tgtgttgcct ccttcttttt gattacatgt ataggatatc
    12121 ctccttttgt aatcactttc ataattttgt ctcattcaaa atgagacatt cctcacatta
    12181 atattcgata attaaataat taaacgtttt tctattttta agcgtaattt attcattttt
    12241 tattctgtat acactttcaa aaaaatattt attcattgaa aaaatttttt tgaataaatt
    12301 aaaaaaataa attatattat cgttgttagc gtttactata tgtattattg ttgtttttta
    12361 tacacaaatc attcgcttca aaacaaatta ttcaatacca ttgtatattt tttacataat
    12421 aacaaattat atttgtaaag tattaaaact tgtttctaat gttggtatgt taaaacttta
    12481 caaattcttt aaaaaaagtg acaataaata tagtgaacaa taaggagagg actttttaat
    12541 gcgtgttaat aaaatcgatt ttcacttttc aaaactcaga tatcaacctg attttgaaca
    12601 tttctcggat gaagagttcc aacagatcaa ggaacatact gttcttcgtt cttataaaaa
    12661 aggacagatc cttttcgacg atggtgatcc cagacaacgg ttgtatatct tgaccaaagg
    12721 actcgttcgt ttagaacgtt atgatgaaag tgcaacttat tactactatg actatgtgaa
    12781 tacaaataac ctttttccta tgtcaggaat gtttggagaa gagacctaca cttatacagc
    12841 tcaagcgatg actgatattg aaacattcta ccttcctgtt tcctactatg aaaaattagc
    12901 acgaaaaaat cccgaacagt tgatctatat gatacaaaaa atttctaaag tagttgaaat
    12961 acatgaattg cgtatccaaa tcggattgac ctctagcgcc tttgaccggg taaaacaaaa
    13021 tttattcatt ttgaaagaag aattgggcgt accaacaaaa gatggtcata tcaccattcc
    13081 ttatccgatc accttaaaag aattagcagt gaatagcggc acgacacgtg aaactgctgg
    13141 acaagtaatc aaacaactac gtgattccgg gctgttagat tatgacaaaa agcgttttac
    13201 tttctgtaag acagctacta ctccagctat gagagaataa cgcgaacaaa aataagcagt
    13261 gaccctgata aatatcaggg tcactgctta ttttcctccc taaaacttct gaaagatccg
    13321 gcagttttag atcactggac aagactcaaa gattttctat gtgtgtttca gttatgtaat
    13381 attcactgtt tgcaaaaaat actgttagat taactagatg aagcgtcttg tcctcatccg
    13441 atctagatta ttcgatattc ctcgacaata aacgattact cagtgagggc aatcagagga
    13501 acggataatg ataaataagc tgtaaaaaat agcaaaataa caataatgat taaaagtatg
    13561 taaaaaatag ggctttgaca aaaacgtgtc acagccctat ttcgattaaa cggtgtgtac
    13621 ctgtcaactc ttcggtcaca agtcataatg ttcataaaca tgaggagctg ttttttgaaa
    13681 ttgttccttg tgaatcagag ttaaacgaca ggcttacgaa ctcttgatta aacggcgttc
    13741 aaaagcttgc atacgcggta ataagaacag ccaggtcaaa aacatgagaa gccgtttttc
    13801 ctgggctgtt cttattactt gatgcagggc agctttttca caacctcttt attcagataa
    13861 aaccaagctt ggatcagcat tcaactgata gctagcaaaa tttctttttt gcatttccac
    13921 atgtgctgct gctccaatca ttgcagcatt atctccacaa agtcgaagag ggggaatcac
    13981 tagttctacc tcagggagtt tagctgccaa agcatcctgc aatccttcac gcaacccttg
    14041 attggccgct acacctccag ctataatcag ttgcttgact ggataatttt gacaagctcg
    14101 aagtgtttta gtaatcaata catcgatcac acttgcttga aagctagctg ctaaatcatt
    14161 tttgtctaga tcttctccac gctgttgtgc attatgcacc aaattgataa atgcactttt
    14221 taatccgcta aaactgaaat cataattatc ttcatggatc atcgctcgcg gaaaatggta
    14281 attatctttt ccctgatgag ctagctgatc gatttctttt ccgcttgggt aagaaagacc
    14341 taatactctt ccaactttgt cataagcttc tcctgctgcg tcatctcttg tctccccaat
    14401 gatttcatat gatccatctt cttgcatata gactaattct gtatgtcctc cgctaacaag
    14461 aagtgccatc aatggaaact ggaatggttt aaccagacgg gctgcataga tatgccctgc
    14521 catatggttt acaggaataa gcggcaattg gtgtgcccaa gcaaaagcct tagctgcaga
    14581 aataccaatc agcaacgagc cgacaagtcc tggtccataa gtgacagcga ctgccgataa
    14641 atcttctgcc gacacaccag cttctaccag tgcatcttcc aagcataagg tgatttgttc
    14701 tacgtgatgg cggctagcta cttcaggtac tacgccacca aaacgtttat gactgtttat
    14761 ttgagaagca acgatgttag ataagatctc tgttccattt ctaacgaccg ctacactcgt
    14821 ttcatcacaa cttgattcaa tcgccagaat caattcttca ttcatttcat cgtctccgtt
    14881 tttaactttc tgctcataat gatcgcatct tccgtcggat tgcgataata tgatttccgt
    14941 ttacctaata tacgaaactt ttctgattca taaagttttc ttgctgcttc attagataga
    15001 cgtacttcta aaaaaacatg cagcgaatct tttatttgtt ccgtaatcag taattgtaac
    15061 aaatgccgtg catgcccttt tccttgttct gaaactgcaa cagcaatatt tgtgatctcg
    15121 acttcatcta ttactttcga gtatccaata aagccacaga tctggttatc ttcagctaaa
    15181 agcagataat cagagtgagg ctgttggatg tctgccaaaa actgcatttt cgtccaaggt
    15241 gaaccatgtg gataagcatt ttcgctaatc atccatacgc attctgccaa gtacgcttca
    15301 tcaaaatctt tttttctgca aatcaactaa tctcactcat tttctaaaag ttttatcata
    15361 tccaacgcat cttcttttgt ttcagtgtaa tatctttttt tgatcgttgt tgcttgaaac
    15421 cccaatttcc gataaagtct ttgtgcatct tgattactca tacgcacttc taatgacatc
    15481 gtctcacagc gattcattat agcaaagttc tcgatttcgt caataagcag cgaaccgatt
    15541 cgtttacgct gatatgccgg tcgaacggca atattcgtga tatggcaatc taaaccgaac
    15601 gctcttgaac cgataaaacc aatcattctt ccattatcaa agatacctag atatagatga
    15661 ggaagcggtg acttcaattc tgatataaag gcactttttg tccatggcaa ttcgccatta
    15721 tagacttctc gttcgacatc cagcagctct ttgatatctt ctgtagtcaa ttctcttagt
    15781 acgtaacgac gatcgatttg ttcgactgtt ttttctgtat aaatcatttt atcttgaaaa
    15841 aagcttctgg catacgctct aaattttttc aacataactt tcgtctccag gtgtgtgcgt
    15901 ctccaaccat ttttcttctg cttctactcg ttttaaatag cgaggaagaa aagcttgttt
    15961 ctctgcaact ggttcaacta aagcacctaa ttgagccaca gttacaccac ttggaatatc
    16021 ccatgctgga actgtattaa tcatcgcact aggcaatatt tcctttattt cagagaagaa
    16081 tttgtgacaa tcactcccga cgaaataaat agcttcattc agcttttgta gttgtgtgaa
    16141 caaatcagaa gcagaaatat gtacatcttc aagtacagtt tctaatctat tttctttcca
    16201 gcggtatgcc ccagcgtata cattttttct tcgagcatca aacatgggca caataatatt
    16261 atccacaccg atgcaattag ccgcgatggt tttcagacta gatactccta ctagctcttt
    16321 atctaatgta taagcaatcg tttttgctgt cgttacacct atacgaagcc ctgtataaga
    16381 accgggacca tcagaaaccg cgattcggtc aatgtctttt ggacttattt gaagatctgc
    16441 aaacaattgg tcgattgcag gcatcagtgt tacactgtgg ttgcgtttga tatttgtttg
    16501 tatttgtcca agaatttgtt cgtcttctac cacaccgatc gccaaagttt ggtttgcagt
    16561 atctattcct aatgtaatca tatatttgat cctttctgct atgacattct cgccttccat
    16621 tgtagcatac ttttttattc tgaggatgaa aataccaaag gcaaaactag tacaataata
    16681 catgattatc tgctggcggg caaattttgc cccttcctga aacacaaaaa agctgcggta
    16741 tcactccatt ttcccacagc ttttccatct tttatttcgt tgattctcga ataatcaact
    16801 ctgtttccac aataatcttt cttgaaaccg gtgctttgga attacttaat tgaagaatcg
    16861 tctccactgc tagctctccc atccattcgg tataaacttt tacagtagaa agcgagggcg
    16921 ttacatattt cgctacactg acatcattga agcccatcac agaaatatct tctggtacca
    16981 ctaaaccttt ttcttgaatc gctttcagtg cgccaatcgc taatgcatca ttagctgcaa
    17041 aaagcgcatc aggaacatgc ggattcgttt ttaaatattg cttcactgct tgatatcctg
    17101 actcgacaga aaaatctgct tcgataattg gaccttcgtc gtagcctttt tctgccaaaa
    17161 cttgttgaaa tgccataatt ctgggatctt ttagccgctg atggtttttc ttcgtatatt
    17221 ctgttccagc aagcatagcg atatgttgcg ctttatggga gacaaagtgt tcaatgactt
    17281 tttgaacact tgacttaaag tcgacaacta gagagtcgat tccttgagaa gtgccgtcag
    17341 aatctaccaa aagcaaggca ttttgggatc ctttcatttc taataactga gcttcgtcga
    17401 attttcctag tgcgatcgtt ccatctgccg gaagatcact aatggaatcc cacgtttctt
    17461 tcaataaagt aacgtttgct tcttctgcct ttttttcgat tcctaggcga atagataaat
    17521 aataaagatc ttcaagctct tccgtatcgt cgtaccactg gatcaggcga agcgtttgct
    17581 tagtatttgc tgcattttta cgatgtttcg tataatttaa gcgttctgct gcttcaaaaa
    17641 ttttttgctt tgtggctaag ccaacggaaa gatcaggatc atagttgaga actcttgaaa
    17701 cagtagcagg agaaactcct gccaactgcg caatgtcttt aattgttgcc atttgtctct
    17761 cctccttttt tacgtttata aaatcgcagt aaatcgttca aacgctgcct gtcctttttc
    17821 atctcgcttg aatactccag cgtcttccag tacacgtgca aaaacctgac ctacagattt
    17881 ttgtacgaca tcggtgaccg tatctttcgt caaatcagga tgttcttttt ttaattgttc
    17941 tgcccacgga cgatgatatt cagccatctg gttttcttct cctaataaga aatgctctac
    18001 ttctactagt tctggtttca aacgaggtgg taaaacagca agccccatta cttcgatcaa
    18061 cccaatgttc tcctttttga tatgttggac atctttatgt ggatgaaaaa tcccatcagg
    18121 atgttcttct gaaacattgt tgtctcgaag gacaaggtcc aactcaaagt aattgtccct
    18181 tcttcgtgca attggcgtaa tcgtatggtg tggtgtacca tctgctgaaa aagctctgat
    18241 agatactgtt tcatccgaat atgctttcca tttttccaat actgagttag ctgcttcaat
    18301 aagcaagttt ttctctgttg attgcaaacg gatcacagac atcggccatt tcacgactcc
    18361 tgcgatgact tgcggataat cttctagttt gataagtttt tctatcggtg cttttgccat
    18421 aggaaattca tgacgtcctg cctgataatg atcatgagaa agaatcgatc ctccaacaat
    18481 tggtaagtca gcattcgaac caacaaagta atgaggcaag acttcagtaa tccgaagcag
    18541 tctagcaaat gtttcctttg tgattttcat cgggcggtgt tgttctgata aaatgatcga
    18601 atgttcattg taataagcat aaggggaata ttggaatccc cagctttcac cgtctagatt
    18661 cattcgaata atccggtgat tggtgcgggc tggatagttc aagcgacctc tatatccttc
    18721 gttttccatg caaagcatgc aggtaggata gtctactttt accgcctcgc gttctgctgc
    18781 gatttgtttt ggatcttttt ctggcttaga taaattgatt gtgatttcca gttcaccata
    18841 ctccgactct gccggaaatt tgatgttttt tgcgatggct cttgttttga tgtagtcatt
    18901 tttcttactt aaattaaaga aatactcagt tgcttcctct gggcttttcg aatagtgctg
    18961 tgcaaagaat gcattgacga ctgaaggtgg cggtgtgaga aaatccatta attgcgcttc
    19021 aaaaatctct tgttctgctg gcaattctga aagaacacca ttttctcttg ccttagcgac
    19081 aagctgatcc aataagtcta cagattcttc cttaactggt cttacttcaa tgctttctag
    19141 agcatcttct cctaccatcc ctaaaagacg attctgtaaa tataagcggt ccatttccat
    19201 ccatccgcca gcttcgatcg caagtgtggc aaaatcacaa atcgtttgac tgattgacat
    19261 atctcattcc cctattcttc ataaccattt ggatggctga catgccaatc ccatgctgtt
    19321 ttgataatcg ctttgatatc tgtgtattca ggtttccagc ccagaatctc tctcgctttt
    19381 tcacttgaag cgactaatcg gctaggatct ccagctcttc ttggtgctat ttctgctgga
    19441 atttcttttc ctgtcacttc tctagctgct tctagcattt ccttgactga gtatcctttg
    19501 ctgctgccta aattgaagaa gttgctttca tttccttctt tcaagtattc caaagctaaa
    19561 atatgtgcag caatcaaatc ttctacttga acataatctc tgatacatgt tccatctggt
    19621 gtatcataat cgtctccata aacagccaag gcttttcttt gaccaagagc tacttgtaaa
    19681 atgattggga caagatgcgt ttctggtgta tgatcttctc cgatagatgc atctgctttt
    19741 gctccggcta cattgaagta gcgcaaagcg acatagcgca tgccatatgc ttggtcacac
    19801 cacttcatca ttttttccat catcaattta ctttcaccat acggattttt aggattagct
    19861 ggtgtatctt ctgtgattgg agactctttc ggctctccat aagttgctgc agtagaagag
    19921 aatacgattt tattcacgtt gaactcgtgc atgacttcaa gtaagatttg cataccgtat
    19981 acgttgttgt tgaaatacat caatggtttt tcgacagatt ctcctactaa agagcttgca
    20041 gcaaaatgga ttactccttc aatcggttcc ttttcaaata cggaacgtag aaattcttta
    20101 tcccggatgt ctccttcata aaaatgagca tctggatgta ctgcttgttt gtgacctgtg
    20161 agcaaattat ctaccacagc tacttgatac cccttttgaa ctagctggtc tacagcgtgc
    20221 gaaccgatat aaccggctcc gcctagtact aaaattgtca taaaaaacac tcctttgatt
    20281 agtaaaattg tgtttgttga ttctatataa tttaaaaaac gaagtttact tttatggtga
    20341 aaacaaacaa agtaaaattt cgtaaattca tatggtaaat ttataataaa acatttagta
    20401 aacattttca agggtttttt gcaaaggttt acaaacaaac gtaaaactag cctttttttc
    20461 tcttttgttc cataatagat ataacaaata ataaatgagg tggattcaat gaaaaaattt
    20521 gtatctggaa tattagtagg aagtctggca acagccgctg ccgttgctgg tttggttgct
    20581 tctgtgaaaa aaacagtgat cgatccaatt gacgaaaaag aagcaatgat cgaagaaaac
    20641 cgtaaaaaag caatgcgtaa acgcgtttct cgttaataat tatttaaaaa tacgcatgaa
    20701 gactttctaa aaaacagata agtcatcatg cgtattttta tttgtcagtc aatataagtt
    20761 gtgctatttt atctgcctgt ctcagattcc atggatctgt ataaggtcta gctactgctg
    20821 cagttagcca atccacacct tcaacaggta ttccatagca ataaaagtca gactggattt
    20881 cccctgaagc atcaatcacg cgattcgtac ctcgctcaac atctatagct tctgaatgat
    20941 aacttcctgt attatctgaa aatgaaaaag ggcgaacaag tttgttttcc ttcaaatttt
    21001 ttatgacagg attacttgaa cgagaaaagc ttgtttgtgg caatcgagct tcaatcaaat
    21061 agcgactgct gatttcttta tcttgtagag aaataacata gcggttgtgc ttttgctgaa
    21121 tatcaaatgg cggttcgatc aaatgaaaaa tacccgcatc tatcagtgct gctaattctt
    21181 tcgtccgaat gattggcgga ccgatcgtta aaaagctatt tagatgagta aaccatcccc
    21241 atagtatttc tttgtattcc ttagcagaaa aaacgtgcca ttcaatagcc tgccggattg
    21301 gatcacgcca gtcttttaat gcatcaaatg ttgaagcaaa tgctcctgtg caattgcctt
    21361 tttccgcttc ttttatctgc ccttcaataa atattcggct agcttctgaa aagggctcat
    21421 tctgataggc aagaggagtt tctaaatacg accaatccca tctataaggg attagtgctg
    21481 gatgctttcc gagacactcc tctgaagaga gggagagaaa atcatgctca aaatttttct
    21541 ttggaatcgg caagtgatat tcttcgatga ttttcttgta ataaaacaac tcaacgtctt
    21601 ttttcagata gtcaaaaaat gtttcgccag tcaaaaatcc cgactgatgc cattgctcca
    21661 ggttttcttt tgttagtaac cgtggccatg ccattgctcc gccttgcttt tgatttcttc
    21721 ctcgagggta ataagggagc ccccttcttg atccactgta tacaatcggt tccttgcctg
    21781 atggatgata gaccagtttt cccttttcgt tctcgaagcg ccctcctctt gatactgtaa
    21841 acaatccgac ataatcaaaa aaacttaagc ctagacctct taaaaagaca ttttctttag
    21901 gcggtatctt cgaaagatct acatctgcag gattagaagg aagctgatac agtaaaacat
    21961 ttttctttgc gtagtctacc cacactcttt cttcttctgt ctcatcattt tcccagtgac
    22021 cgcttgctaa aacaagctga tcgatagaat agctttgctg atctgtctgt aaaagataac
    22081 catcttttct tttgcttact ttttttacta aagaataaac aaactgaata gaagctggaa
    22141 attcttcttg caactttgag aaaaaccagc gttgatagag tccgtataaa catcgagtag
    22201 attgctgatc tttttccaga cgattgattt cttctataat tagttgctta tttttggtta
    22261 ccgtctgttc gatataatct gtagcaggtc ctttactcca ttgaaacaag ttgggtccct
    22321 gtgttaccaa tcctccactg gacaatgttt catctgtaaa aagcgtcact tgttgagaaa
    22381 cagaattcat taataactcc ggtggctgat tcaaccgcca aactcgacct ccaggaccat
    22441 tgggatcgaa aagaaaaagt tcaagagaat gtctgtcctg attattatgg agaatccttt
    22501 ctgctacact taatcctcta ggtccggcac caatgatccc tattttcatt tgcatgcctc
    22561 catttcgata aattttttca ataaaacagc atggttctga tgttcatttt ttgcaccata
    22621 aacaaaagta atgactggat gttctttcat aagttgactg agtttaaaaa tagcttgctt
    22681 cttttcttct tcgaaaatca attcttgctg gtatttcttt gcaaatgaag caaatcgttc
    22741 tggtacatgg tcaaaagttt tgcgtgcttc attactaggt gcaatttctt tcaaccacag
    22801 atctaactgc gctttttctt ttgaaattcc tcgtggccag aatctatcca cgagtattct
    22861 atagccatcc tctttttcag catcaaggta aacacgtttt aatttgatca tagttgtttc
    22921 cttctttcta ccttttcgct tagcttatat atgtagataa tagcacaaaa taaaaaaaat
    22981 gaacggcaca actatccatt gcgccgttca tgtgatcttg gtcaaaatct aatgattgat
    23041 tcggttttta aagctgtcat acaatcatct gttttatact tttttacttt tgatttttcc
    23101 agaccatccg tcatatccac ccttaagtaa ataaatctct tgataacctg ctttacgtaa
    23161 tttatttgct gtacggatgc tcaaactttt cttttgatcg taaatataga caggctggtc
    23221 ttttcgaata gatcctaatg aatctttcaa aacagtgtaa gggatgtttc ttgcacctaa
    23281 aatatgccca gcatcaaaca catctttttc gcgaacatcg attacttgtg cttttctcat
    23341 tccttctcga aattcttctt ctgtcaaagt cgttgctgaa cgtttggcca ttactcgtag
    23401 atagacttcc caaaggatga ttgcaagcac aatcaatagc aaaatgatat taattaccca
    23461 taaaaccatg taatgcctcc gtttttttaa gcaaatttca aggctaatga ggcagcacca
    23521 atgacaccag cttcattacc aagctctgct aatttgattt ttgttgattc tcttacttgc
    23581 gggaaagtaa attctttaaa atatttctct acacggctac gtaaaaattc tcctgctgcc
    23641 gatactcctc cacctaacac gatacttgac ggatttaatg tattccccaa gtttccgcaa
    23701 gctaaaccta agtagaagca tacgcgatca acaaccatca atgcaaacgg atcgtcttct
    23761 tgagccattt caaagatatc tttacttgtt acttcttctc cgttgtctag cattgctttc
    23821 agttttgaat cccctgcgta ttcttctgcc aagaaacgac ctaggcgtac cacacctgta
    23881 gcgctagata cagtttctaa acatccgcgt ttaccgcaag tacattcgaa cccttcagga
    23941 tccacagtga tatgtccgat ttctcctcca gctccgctca cgccgtgaat caaatttccg
    24001 ccagcaacga tacctccgcc aacacctgtt cctagagtaa cgaatacaac gtctggatcg
    24061 ttttctccag cacctttcca tcgttcacct aaagcagcaa cattcgcgtc attatcgata
    24121 gcgaatttga ttcctgttcc tgcctcgatc agttttttca caaattgaac ttctgtccag
    24181 tttaagttat acgcaccaat aaccgttcca gcttcgctgt ccacgcttcc tggggtaccc
    24241 atgccgattc cgataaagtc ttcggctttc atattatata aattcaaacg atgattgatt
    24301 gattcaatga tttcaggaac gatatgctta ccatcatcca aaatattggt atcgatgctc
    24361 catttttgct gaatctctcc ttctggtgtt aaaattgcaa attttgctgt tgttccacct
    24421 aaatcaatcc caataatctt cttgtccatt acaaatttcc tttctttcgg ctttcttcaa
    24481 ttcggtgctc tctttttaat atgcgccacg ctgtcatgta tgtatcatga tcaatcaaac
    24541 ggctatcata cagattacgc aattcgatag tcattaattc aatgtcatag atgcgtgcac
    24601 ccacatagat aaagatgcca aattttttga acagctgctg tacatcatat aagctctcca
    24661 tctttaagca cttccttcat attatacaag taaaccatat ttttttaaac ccagtaaaat
    24721 acatattaca aaaagaaata caaaaactag tgtagaaaga atcctttggt gtatcgaata
    24781 gcttgtctgt tgtttcggta gacccaaaac attccctaac actaatccgc caattagccc
    24841 accgacatgt ccccaaacat ctacagaggt atccagaaga ccaaaaacaa atgtcaacac
    24901 aataaataaa agaaaatgtc tgactagctg ctggatcgct gggttatgtt taaaatgaaa
    24961 ccctaagata aacaacgcac cgaacaaacc gaatatcgaa gtacttgcac caccagacag
    25021 aacattcgct tcgttaaaag caaagcttgc tgtatttccc attatcccgc tgaacatata
    25081 aatcaagaaa aaacgccaat ggccatagat tgcctcgatt tgctgcccca taaaatacag
    25141 tatcagtgag ttcattacga aatgcatcag tccaaaatgg atgaagattg gtgtcactaa
    25201 acgccaccat tcattgaagt gaacaagata aggaccatac attccggcat aataagggat
    25261 ctcaagtcgc ggaaataatt ccatcatgag gaagaccgct gtctgtatcc ctaaaaaagc
    25321 ataggtccat aacggtcgtc ttaaccatgc acgcaatttt atttgctgtt gataattcat
    25381 gaaaacctcc catttcattt tagtcaataa acaattgttg gatcttctga tcaaagctct
    25441 ccggttgcca ttgttcattc aattgttcac gaaaaacaag gctacatgtt tttttatgaa
    25501 aattatttaa ataccggtcg taataaccac cgccaaaacc gattcgataa ccggctctat
    25561 tgtagataat acctggtaca atgaggagat cgatcatctc cggcaaatag agcttctctg
    25621 attgtggctc aagaacacca aaactcgaac gtacaagaac ggactgttca tccatttcat
    25681 aaaacgccat ctgacgtttc ggcaaagttt taggtacaac tattttcttt tgttcttttt
    25741 ctgctcgttg gataaccggc tgtgtatcca gttcaaattc attcgataaa gtcgtcccta
    25801 tcacttttgc tgacttccag tactcgctgg cgaatagctg tttatagatt cgctgttctt
    25861 tttccttttt cttgccactt ttggccagat ttttcagctt ttcgattcct ttccggcgta
    25921 atcttacttt caattggtcc aaaaactcac ccttccttct ctcataaaat ggtataggaa
    25981 aaaaagaaaa atagcaatcg aactttcaaa taaatgcata aatagaataa aaagaagacc
    26041 tagaaatgat tggccttcct tttttaatga atttcaactg ttcagcgcgt gtttttgtct
    26101 gataaaaagt gcatacagaa aatatggcgc accaaaaagg gcaatcaaaa ttcctgtagg
    26161 tacttcccca cttggtagaa tcactctagc aaccatatct gcactaagca gaaaaatgga
    26221 accgaacaaa ccgctcagaa caaaggtcca gttattttct ttacgtacga ctagcttcgc
    26281 agcatgagga gctagtagtc ctacaaaaga taaactacct gtcaccgcta cactaccgct
    26341 tgccaaagca acagctaaca acaaaaggat tttttgactt ttagccacgt taaggcctaa
    26401 tccttgcgcg cgttcttgac caaatgatag caatacaatc ctctgtgcat aaagtcctcc
    26461 tagcggaatt aagataaccg cccatggaag caatgcccaa acataaggcc agctcgcacc
    26521 ccagattgat cccgctaacc atgcattcac aaatccataa ttttccttag ataattggat
    26581 cgtgcatagc aatgttaatg cagaaaggcc ggcattaacg gcaataccgg acaataagat
    26641 tcgattcata cccaaaaagc catttcgatc ataggccgca agatagacac agcaagcagc
    26701 taaaacacca cctagaaagg ctacaactag caatagaaac ggcagcgaat agtgcgaaaa
    26761 gaaacctaaa taaagcatca ctaaaaatcc tgctccggca ttaatgccca atatactaga
    26821 atctgccaat tcatttcttg ttactccttg caagatataa ccagaaacgc caagacaagc
    26881 tcctgctaat aaactgatca gtaatcgagg aactcgaaat tctctaacaa tcagcgccaa
    26941 agaagatgat tctttcccta tgaacgtggc aaaaagctga tccaggtaaa taaaaggcgt
    27001 accaatcatt aaactaccta tagacaggat gacaagtaca aaaagcaaga aatagaacgt
    27061 ccaatatatt tttttcaccg ttgttccctc cttacttgta tcagtaaaaa cggaacgcca
    27121 atcaatgcaa tgactaatcc aaaaggtgtt tcaaaagggg gattgatcat cctcgctgta
    27181 aaatccgcca acataaccaa tccaccgcca actaaaaaag agacaggtag aacataacga
    27241 tagtccgttc caaccattcc gcgaacaact ggcggaacca acagcccaat aaatgaaaca
    27301 ggtccgacta acgaaacggc aatggctgct aacactgcaa ctagacagaa aacaatcaac
    27361 cgcgttcgtt taggatgact tccaagagct aatgcatgtg tttcactcaa atgaatcaaa
    27421 gatattgctt ttcctaatga aaaagaaacc aaaacagcaa gtatatataa aggaaacaat
    27481 actgctaatt gtttccatgt gatattggca gctccgccta caaaccaaaa agcaagatcc
    27541 tgctgcagat taaagaattg ggtaagtgct tggctgatag cagtaaaaaa agaactaata
    27601 gctacgccag ctaaaatcag ctgtaaagga ttcatgccca ttttcgaaaa ctgcaaaaaa
    27661 ccaaatacga gcaaagttac agcaaaagaa cctgccaatg acattagaaa cacagaaaaa
    27721 tcagaagctt taggccaaaa agcaaaacta agggccattg ccaacgaagc acccgcgttg
    27781 attcctagta agcctgaatc tgctaaagga tttcttgtca ctccttgcat caatgcaccg
    27841 ctcaatgcaa aacaactccc tacaagaaat gctcccgcca cacgaggcaa acgaatattt
    27901 cgtatgattt ggtgactttg ttttgatcta tcaaaatcaa acaacgcctg ccaaaaatct
    27961 gctttttcca cagtcgctgc gccatttgaa agagcaacaa aaaaaataat caaaagaaca
    28021 aaacagacca aaagcaggag tctatttttc ttcatagtcc tcataattga tcctcctgct
    28081 cttttggcaa caaatcatag gttagaaaaa ctggtttatt tgttcttgga agcgtgacaa
    28141 tcgttgcatc aatctcaaat atttttttca tacactcttt tgtgatcact tcttcaggtg
    28201 taccttctgt gatcaactta ccgtttttca ttgctaataa ataatctgaa aaacgtgaag
    28261 catgattaat gtcatgaatc gacatcaaga tcgttgtttg tttcatttga ttgatttcag
    28321 tcaataactg taggatctct aattggtgtg ccggatctaa aaatgttgtc ggttcatcca
    28381 agatcaagat atctgtttcc tgagcaagcg ccatagcgat ccagacacgc tgggtttgtc
    28441 caccagacag cgttgcgata tcccgcatac gaaatccagc tagacctgta gcatccaacg
    28501 cccactcaat tgcttcatga tcttgcgtgt ccatgccact gaacagtttt tgataagggt
    28561 atcgtccgta agatactact tcttctactg tcatacctgt agggtgttca ctagtttgtg
    28621 ctaataatgc aatttttttt gcaagttctt ttgaactgta tgtagagata tcagagttat
    28681 tgacaatgat ctttcctgat ttcacaggta gtatacgggt aaaacttttc aataaagtag
    28741 attttccact tccatttggc ccaatcaaac tagtgatttt cccttcagga atcgtaacag
    28801 acatgttttc aatgattttt ttgttttcgt agccggctgc aatgtcagct gctcttaatc
    28861 tcgtcatttc acccatcctt tcgctgaaaa tcattctcaa ttatgacgct gtttcaacat
    28921 ttcgtcaagc gctactttca tatctatagc caaatgaagc ggttgacagc gttcgaaata
    28981 tcaggaataa taaccaatga gaaagattct caattatgtt aggaggaaag aaatgaaatt
    29041 aaaaacaaaa gtattcacat tatctagcat attgctgctg gctggagtac tgagcgcttg
    29101 ctccccctct tcagataaag aaacagctac aactgccaat tcgacgactt catccaatag
    29161 tactcataca gtcacagata cacttggaca taaagtagag attccaaacg cgcccaaacg
    29221 gatcatcggc agttacttag aagactatct gattgcacta ggggaaaaac ctatcgccca
    29281 gtggactgtt ggcagtggtt ccattcaaga ttatctgcaa gatgatttaa aggatgtccc
    29341 aacgatttct tatgaccttc cttatgagaa agtgttaagc tttgagcctg atttgctgtt
    29401 gatttcttct tccgctactg tcgaaggcgg gaaatacgaa caatatagca aaatcgcgcc
    29461 aacttatgtt gtaaaaaacg gaacagatgt cacatgggaa gaacaactaa aagatgtcgg
    29521 caaagctttg gcaaaagaaa aagaggcaga aaaaatcatt tccgattatc aaaaatccat
    29581 caagaaaact cgagaagaac tagcagataa aatcgagaac aagacagctg cagtgttgtg
    29641 ggtgaccaac aactcagcct ttatggtcag caaaaatcgg tcaagtggaa gaatcgtata
    29701 cgacgatctg gaatttggtg ttcctgatct agtggaagag gtctccaaaa aagccacttc
    29761 tgactggtct gctgtttcct ctgaaaagct agctgaatta gatgctgact acatcatcct
    29821 tgtgaacagt gacaaagatg ctgccatgtt caatgaacca agctggaaga atctaaaagc
    29881 agtgacagac aatcatgtac tgcaattcgg acctgaatct agttggctat ataacggacc
    29941 tattgccagt caggaaatgg tcaatgatat caaagaaaaa ctaaattgat tttaactaaa
    30001 aaaagcatct tcacgattag tcgtgagatg ctttttttct tattaacaaa ctagacgcat
    30061 agattttatt cttcttttga agcaacccta ttttttactc tttcccattt ttgaaaacga
    30121 tgggcatata gattttcttg atccgttatc ccctcatact cctctataag ggcgaagtct
    30181 gaaaaatcaa tattcccaat atacgtatcg ccttcaaacg tgctatcgat caatgttcgc
    30241 cagatccgac cagtgtaagg aagaagttct tgaaaaatcc gactaccacc cgaaacatag
    30301 atatcttctg agatcgtttg actatacgac aaaagttcat cgatcgaatg cattacttcc
    30361 gcattttctt tcgtgcgaaa atttggttgc gttgtcaaca cgatgatatg gcgataagga
    30421 agtgaaagat cccccattcc ttcataggtc tttcttccca tcactaaaat tcgatccatt
    30481 gtatgttcgc gaaagaaacg catatcattt ggcaatcgcc atggtaacaa accatttttg
    30541 ccgatcagac catttttatc ttgtgcccac atggaaataa acatattatc cgctccttat
    30601 gattttagat gttttgagat aaaaaaagtc tcaattcttt gaccagcaag gaattgagaa
    30661 ctttaaaaac attattttgt ttcacggtgc aaagtaactt tgcgttcgcg tgggcaatat
    30721 ttttgttttt ccaaacgatc aggattgtta cgtttgtttt tgcttgttag atagttacgt
    30781 tctttacaag aagtacactc taaagtgatg tttacgcgca tgtttttccc tcccattttt
    30841 acaagaatcc tctaagatga ctctcagact tgattatctt accatgattt tttctagatt
    30901 gctagtgttt ttcacgattt tgttaagtaa aactacttga cgataaatac aacggtttta
    30961 cttctcaaac aaaatctttt tctttttgta taaataccct tacacttgtt tatatagatt
    31021 atgtttttta ataaaggggg atactaatat gccatggaac atgaaggact ttcctgcatc
    31081 aatgaaaaac ttagataaat tgacaagaaa aaaagcaatc gacatcgcaa atgcattatt
    31141 agatgaaggg taccctgata accgtgcgat cccaattgcc attgatcaag caaaaaaatg
    31201 gtatgaagat gctagtgaat cagaaaaacg aactttcgaa aaagaaaaaa atccaagcaa
    31261 gacggatgaa cacgatacga atcctcgtgc tggaaaactg cttgattcag atgtgatcgt
    31321 agaatatgag gaagaacaat ggatcgtgaa atctaaaggg gcaaaaaagg caagcaacca
    31381 ttttgataca aaaaaagaag caatcgaaaa aggaaagcaa gtagcacaaa acaaagaatc
    31441 aactttgttc atttataaaa aagatgggac aaaagaaaaa gaaatcgatt attgaacata
    31501 tgtaaagggg ttgtgacgaa aatcgtgtca caaccccctt atgttcgaaa caatggtgtt
    31561 cctctgccaa ctccgaacca taagtcataa tatctataaa acgggaagag ctgttttttg
    31621 aaattgtttc ttatcactca gtgttaaacg gtaggagaaa acctcttttt tattgatatt
    31681 tgattttcat caaacagtca catagtcgat tgcttctgct tgcggaatcg tttcatctac
    31741 aaagtagact ttataccatg tcaagaaact gaagattgtc cagatttttc tttgctcttc
    31801 tttacgtcct tcgtgatggt catctagcaa cttcatgatt ttttcttgat caaaaaattc
    31861 ttttgcaaaa tctgcttcga ataatgcttt gacttgttcg tagccgtgtt cttctttcaa
    31921 ccaagctttg attggcacag ggaatcctaa tttcacacga ttcgaccatt cttccggaag
    31981 atgtttgttc gcagcttgtc tgaaaatatc ttttgtgttg ttttgattca ataaaaactt
    32041 acttggtatt tgttgagcca atttcatgac ttcgatatcc aataaaggta ctcggacttc
    32101 caaagaactt gccatagaaa gtttatctgc ctttaacaag atatcttttg gcatccattg
    32161 atgaagatcg acatattgca tcttattgac ttcatctttg attccttctg ttttctcgta
    32221 atgaacagtc atgatttcat ccacagatgg tgctgtttga tattttggtg ttaacacttc
    32281 tgatgcttct gattcttcga acactcgagc atgaccgata aaatattctt ttgcaggagc
    32341 aagtgattca tataaatgga tccgtccatg gaagtttttc atttttccga ttttacgtcc
    32401 taaattatag cgtgttcctt ttggtaattt tttcaatcct tgagcaatca cacggatgaa
    32461 ttttgaattc gtatggaatc catacgtttg gtatcccgca aacagttcat ccgccccttc
    32521 tccagattgg actacccgca cactttgtga agcaagattt gctaaaaagt acaaaggtac
    32581 gcaagaagga tttgaatcag gttcatctaa gtgatactgg atcaaaggga atgctttgaa
    32641 cgacatgtct ccgtcgatca ctgctgctgt attatctaag tccaatagtt cggttagttt
    32701 tctggcttca atcgcttcat tataggtttt atcatcaaac ccgattgaga aagaatgatc
    32761 tggtttcaat acagaggtta cataactgga atcaaccccg ctggataaga aagaaccaac
    32821 ttctacatca ctgaccgtat gtgcttcaat agaagcttga acggtttcgt cgattttttc
    32881 gatccattct tgtcgggaat gcgtttcttt tgtttcaaaa tctgcatccc aatattgctg
    32941 aatgtctatt tttccatctt tatacgtata ataatggcct tcaggcaaac gatagacatc
    33001 tttgaagaat gtttcgccgt ttaatggaga atattggaaa gtcatataag gtttcaacgc
    33061 ttctttgttc aattctttgt taaaatcagg atgaggcaga aaacttttga tttctgaacc
    33121 aaacataaat gttccgttca tttctgcata ataatatggt ttgatcccaa agtggtctct
    33181 tgcaccgaat aactcattct tttcattatc ccaaatagca aaagcaaaca ttccgcggat
    33241 cttttgcaat aattctgttc cccattcttc gtaaccatgc aaaaggactt ctgtatctgc
    33301 atgtgtttga aaaacgtggc cagctgcaat caattcttct ctcaaaggct ggtaattata
    33361 gatttcgcca ttaaaaataa tgatctttgt ccgatcttca ttgtaaatag gctgagtacc
    33421 gccctctaag tcaataatac ttaatcttct gaatcctaaa gcaacatgtt tatcgatata
    33481 ttctcctgaa ctattaggtc cacggtgaac gattcgatcc atcattgtat taataattgt
    33541 ttttttgttg tccttgtcgt taacaaaacc tacaataccg cacatttaac tttcacatcc
    33601 taatataaaa ttactgttta tttcattcat atgcatctta tcatagaata aatagcggac
    33661 gaatattttc tctcttacaa tttcgtcacg tgaaaacaaa agatgaaagt ttctgttttt
    33721 acagaaaata aagtcccaat atctaattta ccatgttttc ttttttgagg ctaccttatt
    33781 ctcttcgtgt taaaaaaata ttagtggatg ctatttccaa aaaaaccagc aaaaaaagac
    33841 acgacctaaa gatcgtgtc
//
LOCUS       DADGKS010000024        33263 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.024, whole genome shotgun sequence.
ACCESSION   DADGKS010000024 DADGKS010000000
VERSION     DADGKS010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33263
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.024"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(41..229)
                     /locus_tag="JXV47_001276"
     CDS             complement(41..229)
                     /locus_tag="JXV47_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HAX1487330.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            499..861
                     /locus_tag="JXV47_001277"
     CDS             499..861
                     /locus_tag="JXV47_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAX1487331.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            913..2595
                     /locus_tag="JXV47_001278"
     CDS             913..2595
                     /locus_tag="JXV47_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HAX1487332.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKETPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            2712..4748
                     /gene="recG"
                     /locus_tag="JXV47_001279"
     CDS             2712..4748
                     /gene="recG"
                     /locus_tag="JXV47_001279"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HAX1487333.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKEFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LLTGSTKAKERRELLEKLEQGEINIVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            4797..5798
                     /gene="plsX"
                     /locus_tag="JXV47_001280"
     CDS             4797..5798
                     /gene="plsX"
                     /locus_tag="JXV47_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HAX1487334.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            5920..6162
                     /gene="acpP"
                     /locus_tag="JXV47_001281"
     CDS             5920..6162
                     /gene="acpP"
                     /locus_tag="JXV47_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAX1487335.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            6430..7434
                     /locus_tag="JXV47_001282"
     CDS             6430..7434
                     /locus_tag="JXV47_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1487336.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            7435..8379
                     /locus_tag="JXV47_001283"
     CDS             7435..8379
                     /locus_tag="JXV47_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1487337.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            8379..9341
                     /locus_tag="JXV47_001284"
     CDS             8379..9341
                     /locus_tag="JXV47_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1487338.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            9368..10282
                     /locus_tag="JXV47_001285"
     CDS             9368..10282
                     /locus_tag="JXV47_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1487339.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            10308..12089
                     /locus_tag="JXV47_001286"
     CDS             10308..12089
                     /locus_tag="JXV47_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAX1487340.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            12437..13123
                     /locus_tag="JXV47_001287"
     CDS             12437..13123
                     /locus_tag="JXV47_001287"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAX1487341.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            13143..16724
                     /gene="smc"
                     /locus_tag="JXV47_001288"
     CDS             13143..16724
                     /gene="smc"
                     /locus_tag="JXV47_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HAX1487342.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            16733..17542
                     /locus_tag="JXV47_001289"
     CDS             16733..17542
                     /locus_tag="JXV47_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAX1487343.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            17553..18551
                     /gene="ftsY"
                     /locus_tag="JXV47_001290"
     CDS             17553..18551
                     /gene="ftsY"
                     /locus_tag="JXV47_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HAX1487344.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            18738..21005
                     /gene="gshAB"
                     /locus_tag="JXV47_001291"
     CDS             18738..21005
                     /gene="gshAB"
                     /locus_tag="JXV47_001291"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HAX1487345.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKKYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(21094..21546)
                     /locus_tag="JXV47_001292"
     CDS             complement(21094..21546)
                     /locus_tag="JXV47_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HAX1487346.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            21696..22646
                     /locus_tag="JXV47_001293"
     CDS             21696..22646
                     /locus_tag="JXV47_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAX1487347.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            22639..23598
                     /locus_tag="JXV47_001294"
     CDS             22639..23598
                     /locus_tag="JXV47_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAX1487348.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            23595..24350
                     /locus_tag="JXV47_001295"
     CDS             23595..24350
                     /locus_tag="JXV47_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAX1487349.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            24373..25326
                     /locus_tag="JXV47_001296"
     CDS             24373..25326
                     /locus_tag="JXV47_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HAX1487350.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(25970..26266)
                     /locus_tag="JXV47_001297"
     CDS             complement(25970..26266)
                     /locus_tag="JXV47_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HAX1487351.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            26621..26977
                     /locus_tag="JXV47_001298"
     CDS             26621..26977
                     /locus_tag="JXV47_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAX1487352.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            26987..27886
                     /locus_tag="JXV47_001299"
     CDS             26987..27886
                     /locus_tag="JXV47_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HAX1487353.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            28403..29134
                     /locus_tag="JXV47_001300"
     CDS             28403..29134
                     /locus_tag="JXV47_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAX1487354.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            29279..31306
                     /locus_tag="JXV47_001301"
     CDS             29279..31306
                     /locus_tag="JXV47_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lectin"
                     /protein_id="HAX1487355.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRINIPVENQRIGTFEGKLSWILADVPGN"
     gene            31414..32511
                     /locus_tag="JXV47_001302"
     CDS             31414..32511
                     /locus_tag="JXV47_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAX1487356.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            32818..>33263
                     /locus_tag="JXV47_001303"
     CDS             32818..>33263
                     /locus_tag="JXV47_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAX1487357.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
BASE COUNT        11138 a         5762 c         7123 g         9240 t
ORIGIN      
        1 aaaaaccgtt cactatctga acggtccaag tatcattcaa ttaaacgcgt tcaacttttc
       61 ctgatttcaa agcacgagtt gacacccaaa cttttttagg ttttccgtcg accataacgc
      121 gaactttttg taagttaggt ttaacagtac gttttgttga gttcatagcg tgtgaacggt
      181 tgtttccact ttttgtcttg cgacctgtaa agtaacaaac ttttgccatg gtaatttcct
      241 cctttgcctt gatttggagc aatagaataa ttcagctcat accagactaa catatcatat
      301 agaatggaaa tttgcaagta cattttcata gatacaattg acaattgaga agaataattg
      361 taaattaaac aaggttatac ctgaaatttt gcaaggtttt tgagtacttt gggtaactgc
      421 cttttatttc aagttgcgct atgataaaat atgatagaag aaaaatggga gttttttacc
      481 cgttaaggag gctcattcat ggctgtaaaa attcaaacgt cagctggaac cattgaaatt
      541 accaatgatg taattgcaac agttgttggt ggcgccgcga cagatgtgtt cggtgttgta
      601 ggaatggcca gcaaaaatca aattaaagat aatattactg agattttgcg taaagaaaat
      661 tactcaagag gagtagttgt ccgccaagaa gataatggta ttgctgtaga tgtttatacg
      721 attatcagct atggtacgaa aatctctgaa gtttcccgca acgtccaaga aaaagtgaaa
      781 tacaatctag aggcattatt aggcgtaact gccaattcag ttaatgtctt tgtacaaggt
      841 gttcgtgtac tgccagacta ggcaggagac tggctggtaa ctcagcagtc gatctgaagg
      901 aggattatct aggtgagtgt aacagaaata agtgcaagcc agttccagga aatggtccag
      961 gcaggtgcga atcgtctgca agtaaatgca gaatacgtca attcattaaa tgtattccct
     1021 gtgccagatg gcgatacggg aacaaatatg aatctatcta tgactagtgg agctaaggca
     1081 gtagtagatt caacctcaga aaaagtagga gaattagcag caatgctttc aaaaggattg
     1141 ctgatgggtg cgcgcggaaa ttccggcgtt attttgtctc aattgtttcg tggattttct
     1201 aagcaaattc cagatgttgt ctcattaaat gcttccgatc ttgctgcagc cttcactcat
     1261 ggagttgaaa ctgcgtataa agcagtaatg aaaccagtag aaggaacgat tttgacagta
     1321 gctagagaag cagcgaaagc tggagaaaag aaagcaaaaa gtactgatga tgtcgttgaa
     1381 gtaatgacag ctgttgtaaa aggggcaaag cgtgctttag ctaaaactcc agacttgctt
     1441 ccagtcctaa aagaagtcgg tgtcgtagac agtggagggc aaggactgct gtttgtttat
     1501 gagggctttt taagtgcatt gaatggagaa ttccaagcgg atgaaacata tgaaccttct
     1561 ccagcagaaa tggatgatat ggtcaatgca gaacatcatc gcagtgtcca aggtcaaatg
     1621 gcgacagaag atatccattt tggttactgt acagaaatca tggtaaaaat cggagaagga
     1681 cctacagtcg atagtacatt cgattacgaa gaattccgta actatttaga tggtatagga
     1741 gattctttac ttgtggtcaa tgatgacgag atcatcaaag tccacgtgca tacagaaaac
     1801 ccaggagaag tcttgaatta tggacaaaaa ttcggttcat tagtcaaaat caaagtcgac
     1861 aacatgcgct tgcagcatga gacgattttg gaacacgatg aagaagtgaa cgagtttgcg
     1921 aaaaaagaaa caccacgtat cccgtatggt atcgtagcga tcgctgctgg taaaggcgtc
     1981 caagagctgt ttgaaagttt aggcgctaat tatgttatca gtggtgggca aacaatgaat
     2041 ccaagtacgg aagacattgt taaagcgatt caagaagtaa acgcagataa agtgattgtc
     2101 ttgccaaaca ataagaacat cttcatggca gctgatcaag cagcagaagt agcagatatc
     2161 ccagtagcag ttgttccttc aagaacgatt tcccaaggat tgacagctat gctttcattc
     2221 aatgatcaag cttctttaga agaaaacaaa gaaacgatga cagaaatgtt gtctagcgtt
     2281 gtgagcggtc aagtcactca cgcgatcaga gatacctcaa ttgacggtgt agagatcaaa
     2341 gaaggagact ttttgggcat gatcgatgga aaaatcctga tctctaaccc agatatcaca
     2401 gcaacagcgt taagtacact agaacaaatg atcaatgagg acacagagat cgtaacgatc
     2461 ttggcaggtg atgaaggaac agttgaacaa gcaaatgaat ttgctgagaa actaacagaa
     2521 aaacatcctg atttggaaat cgagatccac caaggagatc agcctgtcta tccttatcta
     2581 ttttctgctg aataatttct gtgtcagaat atctttctaa cacagtattc attcataaaa
     2641 ggccttcggt tagtgatcag gtatgatcgc tgaccaagtc ctttttttgt taagggaggg
     2701 aggaaaaatt tatgcgttct ttagatgatc caatcactat gctggcagga gtcggagaaa
     2761 aaagagcagc tagtcttgcc agcttgggca tccaaacgat tgaagactta ctgacttatt
     2821 atcctttccg ctacgaagat attcaggaaa gaaatctaaa cgagatccaa gatcaagaaa
     2881 aggttacttt gaaaggaatc gtagtctcgc ctcctgtgat gaatcgattt ggttataaaa
     2941 aaagccgatt gcaatttcgt atgatgcaag aacatgatgt gttcaacgtt tcttttttta
     3001 atcaacctta tctaaaagaa aaagtcattt tatcggagga aatcgccgta tacggtaaat
     3061 gggatgcaaa gcgtaaagca ttgaacggga tgaagatttt aggttctcaa acaatggatg
     3121 acttttcgcc gatatatcac gtcaacaaat caattcgtca aacgacatta gttgatctaa
     3181 tcaaaaaagg gtttcaagaa tacggcacat tgattgaaga aaatctgcca aacaaccttg
     3241 tggagaaata tcgactgctt gaccgagctt ctgctgtaag aagtatgcat tttccaaaag
     3301 accacgaaga aaaccatcaa gccaaacgac gtgtcgtttt tgaagagttc tttttatttc
     3361 aaatgcgtct tcaaggattg aaaaaagcag aaaaagcaga aacgaatggt ttggagatcc
     3421 tttatgatgt ccaaaaattg aaagaattta ctcaaaagct accttttgaa ctgacaaatg
     3481 cacaaaaacg tgtaacgaat gaaatctgtc gggatcttcg cagtccgcag catatgcagc
     3541 gacttttgca gggagatgta ggtagcggaa aaacagtggt tgccgcgatt gcgttatacg
     3601 ctaccgttac agcaggtttc caaggtgcgt tgatggtgcc tacagaaatc ttggcacaac
     3661 aacatatgga aagcttgcaa cagctgtttg atcccaatga agtaaccatc gcattgctta
     3721 cggggtcaac gaaagcaaaa gaacgtcgtg agctccttga aaaactagag caaggggaaa
     3781 ttaacatcgt gatcggcaca catgcattga tccaagatgg agtcgaattt cagaatttag
     3841 gtctagttat tacggatgag cagcaccgtt ttggcgtgaa ccagcggaaa gtacttcgtg
     3901 aaaaaggctg gcgaccagat gtcttattta tgacagcgac tccgattcct agaacattag
     3961 ctattacagc atatggtgag atggatgtat ctatcattga tgaacttcca gctggacgta
     4021 tcccgatcga aacacgctgg gtaagaacac ctcaattgga cagtgtactg gattggacga
     4081 aaaaagaact ggcaagagga catcaaatgt atgtcatctg tccgctgatt gaagaatcag
     4141 aagcattaga tgtaaaaaat gcagtggaaa tctatgaaaa acttcgtgaa ctatttgcac
     4201 caaaatatga agttggcttg ttacatggta aaatgaagaa tcaggaaaaa gaagtaatca
     4261 tggaagcctt caaagacaac cagatgcaga tattagtttc gactactgta attgaagtag
     4321 gggtaaacgt gccgaacgcg accgtcatgc tgatcatgga tgcggatcga tttggattgg
     4381 cacagctgca tcaacttcgt ggacgtgttg gacgcggaag tgatgcttcc tactgtatct
     4441 tagttgctaa tcctaaaaat gaactaggtg tggaacggat gaaaatcatg acagagacca
     4501 ccaatggttt tgtactaagc gaaaaagatc tggaattacg tggtcctggt gaagtatttg
     4561 gcttccgtca atctggtctg cctcaatttg cgattgctga cttggtgacg gatggaaatg
     4621 ttttggaggt agccagagaa gaggctgcag ccctttggca gataaaggat tggcagatgc
     4681 ttcctgagta tcagccttta gcgcaaagcc tccaaataga aaatcaggat aatcgttatt
     4741 tcgattagca gactgtgcta tactttatac tgatgacgga aaaaggagtg gaaacaatga
     4801 aaattgccgt agatgcaatg ggcggagatc acgcacctca agcaattgta gaaggcgtgg
     4861 ctttagcgca gcaagatttt ccagaagtag aattcttact ttacggaaaa gaagcagaaa
     4921 tcaagaaata cttaacaaat gaaaaaaaca tcacgattat ccatacagac gaaaaaatca
     4981 atagtgatga tgagccagta aaagcaattc gacgaaaaaa gactgcatca atggtccttg
     5041 ctgcacaagc agtgaaaaac ggtgaagcag atgctgtatt ttcagcaggg aatacaggcg
     5101 cgctactagc agcagggttg ttcatcgtag gacgtatcaa aaatatcgaa cgccctggct
     5161 tgatgtctac cttgccagta gtagggaaag aaggtgccgg tttcgatatg ctggatcttg
     5221 gcgctaacgc agaaaacaaa ccagaacatt tgttgcaata cggtatttta ggttcttttt
     5281 atgcacgtaa agtccgaggt atcggacgtc ctcgtgtcgc actcttaaac aacggaacag
     5341 aagcaacaaa aggtagtgaa gtgacgaaaa aagcctatga actccttcag aatgaaacaa
     5401 gcttgaattt tattggaaac gtagaagctc gtgagctact caatggtgtg gctgatgtag
     5461 tggtcacaga tggatttaca ggcaacgctg ttttgaaatc tattgaagga acagcaatga
     5521 atatgatgaa tctattaaaa tctgctattc taaatgaagg gatcaaagga aaaatgggcg
     5581 ctatgctttt aaaagacggc ttacgttctt tgaaagcaga aatggattat tccaaacatg
     5641 gcggtgccgt tttgtttggc ttgaaagcac cagtcattaa aactcatgga gcaacaggcc
     5701 ccgatgctgt tcgctatacg atccgccaaa tccacacaat gcttgagaca gatgtagttg
     5761 gacaattagt cgaacaattt gaaaaaagcg aagaatagta tttggatatc tgaagcaatc
     5821 cgttccattg aaaaaaaggt ggacattcct gaaaaatgcc agtaaaatta gccatggtgt
     5881 aggtaattga caagtgtatg attcttggag gtgaaaaagt tgactcgcga agaagtattt
     5941 aacaaagtag cgaaaattat ttcaaatcat tttgagatag ataccgataa agtgacggat
     6001 gaattgaaca tcaaagatga tttaaaagct gattcaatta gtattatgga attcgtttta
     6061 gagcttgaag atgaattcgg tacggaaatt tcagatgaag acgctgaaca aattgaaaca
     6121 gtcggtggcg cagtagatta tatcagcagc catcttaaat aatttcaaat aaaagcaaag
     6181 aaggataaaa agctgcatac agctttttat ccttcttttt ttaatctttt tgacacgtaa
     6241 aagtcatttt tctgataatt ctggcgataa acagaaatta tgttgcaaag taaagcgatt
     6301 ttctatataa ttattaataa ttcattacac aaagataaga ataacctttg ttataaaacg
     6361 ctttattctg tgtaatgtcc ttttttatta agaaaaactt ccatttagga agcagagagg
     6421 ggtattcgat tgtccgataa ccaattatta gaagttcaga acctacatac aggattccga
     6481 ctcaaagatg actattacga tgcagtagat gacgtttcat ttactttaga caaaaacgag
     6541 attttagcaa tcgttgggga atctgggtgc gggaaaagta ccttggctac tacgattatg
     6601 ggattacttg atcctaataa cacaaaaatt acaggtgaga ttttatataa cgatctgaat
     6661 ttaatcgacc tgaacgaaac gctctataat aaaatccgcg gaaatgatat cggaatgatt
     6721 ttccaagatc cgttgtctgc attaaatcct ctcatgagaa tcgaagacca gatcaaagaa
     6781 ggactttcct atcacacaaa gatgaatgca gaacagcgtc aagctcgtgc actagaattg
     6841 ctagaacaag tagggattcc taatcctgcg agagttggac gccaatatcc ccatgaacta
     6901 tcaggcggta tgagacaacg tgtcatcatc gcaatcgcaa tcgcctgcaa acctccaatc
     6961 gtcattgcag atgaaccgac gacagcccta gatgtaacca tccaagcaca gattcttgat
     7021 ttactgaaag accttcagga agaaacaaaa acagggatca tcttgatcac tcatgactta
     7081 ggagtcgtag cagaaatggc tgatcgagtg gcagtgatgt atggcggaca gttcgttgaa
     7141 gtagcaggtg taaaagaact gtttgatcat cctaagcatc cttatacacg ctctttactg
     7201 aactctatac cacaagaagg aaatcatgat gcagaactcc atgtgatcga aggtgtcgtt
     7261 ccttctctga aaaacatgcc tcgtaaaggt tgtcggtttg caccacgtat tccatggata
     7321 ccagcaagcg atcatgaaga agagcctatc cttcatgaag tcgcaccgaa ccacttggta
     7381 cgttgctcct gctataagca tttccacttt agagacgaaa aaggagaggt gtagatgaca
     7441 gaattaatca caatcaaaga cctgaaagtt cattacccta ttcgcagtgg attcttcaat
     7501 cgagtaacgg atcatgtata tgctgtagat ggtgtggatt ttattatcga aaaaggaaag
     7561 acatatggtt tagtgggaga gtctggctct ggaaaatcta ctacgggaaa agccgttgtg
     7621 ggattagaaa aggtaacagc cggacaaatc atgtatgaag gaaaagatgt aacgaagcga
     7681 agcaaccgca aaaaaatggg ttataacaag gatgtgcaga tgatcttcca agattcaatg
     7741 tccagtttga atcctaaaaa gcgagtgttg gatatcattg ctgaacccat ccgaaatttt
     7801 gaacggttaa gcgatcaaga agaaaagaaa aaggtaaaag gactgctaga tatcgttggg
     7861 atgccggaag atgcgctata taaatatcct catgaatttt caggcggaca acgtcaacgt
     7921 ctaggagtag cccgtgctgt tgctaccaat ccaaaactga tcgtagccga tgaacctgta
     7981 tctgctctgg atctatctgt tcaagcgcaa gtattgaatt tcatgaaacg aatccagcaa
     8041 gaatacggcc tcagctattt attcatttca catgatttag gtgtagtaaa acacatgtgc
     8101 gacaatatcg caattatgta caaaggtcga tttgtagaaa tcggtacaag agaagacatt
     8161 tataatgacc cgcgacatat ctatacgaaa cgtctgcttt cagctattcc gcaaatcgat
     8221 gtagaaaata gggaaagcca caaagaaaat cgacgaagag tagaacaaga gtatatccaa
     8281 aaccaaaaag aatactatga tgcgactggt cgagtctacg atttgcgtac gatcacaact
     8341 acacacaaag tggcgttgaa agatggaggt gcaagctaat gtggaaaacg attctgcgac
     8401 gtgttttatt gatgatcccg caagttatta ttttaagtgt tctgatcttc ttattagccc
     8461 aagcgatgcc gggggatcca tttaccggtt tgatcaatcc aaatcaggat ccggcagtga
     8521 tcgaacagat gcgacaagca gctggcttga atgacccatg gtatgtccag tacttccgtt
     8581 ggatcggaaa tgctttgcaa ggcgattttg gtcaaagttt cttatacaaa cgctctgttg
     8641 ctgacttgat cggcgaacgg atcatcaaca ctttatatct atcgatcttg acagttgtcc
     8701 ttacttattt gattgctgtg cctctgggga tgcttgctgg ccggtatcaa aattcaatct
     8761 tggataagat tgtcgtaatc tacaacttct ttagttttgc tgttccttta tttatcttcg
     8821 gcttgatcat gctatttgtt tttggttatc gtttaggctg gttcccaaca agtggatcac
     8881 aaacactagg tttgcaaggt ggatttatca ctcaatggat agaccgtttg aaatatattc
     8941 tgttaccatc aattacccaa gcatttttgg cgactgccgt cacaatccaa tatctgcgaa
     9001 gtgaagtaat cgattcgaaa tcgctcgatt ttgtcagaac agcccgttcc aaaggggtac
     9061 cgacgaataa agtattcagt cgacatattt tccgaaatgc agcgttgccg atggcttctc
     9121 aaatggggta tgaaatcact tcgttgattg ctggttctgt agttatcgaa aagatttttg
     9181 gttatccggg agtcggaaaa ctatttattg attccatcgg ccaacgggac tataccgtga
     9241 tcacatcctt agtattgatt ttaggaatcg cgacgctagt ggggacatta ctttcagata
     9301 tcatcatgag tatcgttgac ccgcgtattc ggattcaata aaaccaatca gaaaggagaa
     9361 tggatcgatg agtgaaaaaa acaatacagc agttcaagaa agtattcctc ctatggggat
     9421 acgaatgatt gctcgagaat ttaaaaaaga taaaattgct attttttcat taggtttgct
     9481 agtggtttta ttattagtga tctttatcgg tgcgatgctg accgatcaag acaaagtgat
     9541 gtatgttagt atcttcgaca aatacgctgc accaggaaca gtttcgacac aaggacaaaa
     9601 gttcattctg ggagcagatg aaggcggacg tgatgtatta ggacaattga tcataggtgc
     9661 tagaaactct gttacgatcg gatttgcgat cacgatcctt acttcgatca tcggggttgg
     9721 attagggatc atctctggct actacggagg gatcattgac aacatcttga tgcggatcgt
     9781 tgattttatc atgattctac cgatcatgct gatcattatc gtcttcgtat cgattatttc
     9841 cagatacaat gtctggtcct ttatattcat catgagtgca ttttattggg tagctaaagc
     9901 ccgattattc cgaagcaaga cattatctga agcaagaaga gattatgtca gtgcctcaaa
     9961 aacaatggga accaatgatt ttaaaatcat gttccgcgaa atcatgccga atctaagttc
    10021 attaatcatt actaatttga cgatgaactt tgcggcaaac atcggtatcg agacaacttt
    10081 gactttctta ggtttcggct tgccggcaaa tgtacctagt ttaggtacat tgatcggtta
    10141 tgcaagtaac ggagaagtct tagtgaatcg gcaatggatc tggttacccg catcaatcct
    10201 tattttagtt ttgatgttga gtatcaatta tgttggacaa gcattcaagc gttctgcaga
    10261 tgcgcgccaa cggttaggct agtatagaag cgaaggggga aataggaatg aagaaaacga
    10321 tttttggatt tgcagcgctg atgtctgctg tcgttcttgc agcatgcggg ggcggaggta
    10381 cagatacctc tggaaacaac tctggaggca acggcaataa caaagaggaa ttaacttttc
    10441 caattgcaac aaaaaataat gatgatgcaa tcgaagacgg cgaattagaa gctgcggtcg
    10501 caacggacag tcagtttaaa ggattgttcc agtgggagtt ttaccaagat tcatatgatg
    10561 cagcttttat ggctccttct catgaaccgc tatttgcaaa cgatgacgat ttcagaatca
    10621 cagacgacgg agctgcaacg cttgatctag atgaagatac gaaaaaagcg acaatcaaag
    10681 taaaagacaa cgtcaaatgg tcagatggtg aagatgtaac ggcggacgat gtgattttcc
    10741 cttacgaaat cattgggaat aaagattaca ctggtatccg ttatgacgac actttccgta
    10801 acatcgtagg tatggaagaa tatcatgatg gaagtgccga cacaatctcc ggaatcaaaa
    10861 aaatagacga caaaacagtt gaaatcgaat ataaagaagt aaacccaagc atgcttcaat
    10921 cgggtggtgg tatctggtca tatgcagcac caaaacatac gttagaaggt gtagcaatca
    10981 aagatatgga atcaagcgat caagtacgta aaaatccagt gacttttggc ccttattaca
    11041 tgagtaatat cgttgcagga gaatcagtag aatacttgcc aaacgagcac tactggaatg
    11101 gtacgcctaa attgaaaaag atcacgatga aatctgtacc gatggcaagt gcaactgaag
    11161 cattgaactc taaattatat gatatgattt tccaaatgcc aacagatact tacgatacct
    11221 ataaagaaat tgctggctat acaaacttag gccgtgaaca aacttcttat acttatctag
    11281 gattcaagtt aggtaaatgg aatgcagata caaagagtgt ggaatacaat ccagattcaa
    11341 aaatggctga taaatcatta cgtcaagcaa tgggctatgc attagataat aatgcagtag
    11401 gtgaacgttt ctatgcaggt ttgagaagca atgcgacttc attgattcct ccagtattcc
    11461 agtcatacca tgatgatgag atgaaaggat tcacacaaga tctagacaaa gcgaaaaaac
    11521 tattagatga tgctggctac aaagatgtgg atgacgatgg tttaagagaa gacaaagatg
    11581 gaaataaact aacaatcaac tttgcttcga tgtccggtgg ggaaacagcg caaccattgg
    11641 cagattacta tatccaacaa tggaaagaaa ttggtttgga tgtccaatac acaacaggtc
    11701 gtctgatcga attcaattct ttctatgata aattagaaaa cgatgatcct gaaattgatg
    11761 tttaccaagc tgcttggaat acaggaactg atccaaatcc aagtggacta tggggaccaa
    11821 atgctgcgtt caactacact cgttatgaat cagaagaaaa tacaaaattg atcaacgata
    11881 tcagttcaag caaagcattt gatgaagagt accaaaaaga agcatatcaa aaatggcaac
    11941 aatatgcatt tgaagaagca tttgcgattc caacgttgtt ccgtaatgaa gtattgccag
    12001 tcaacgaccg tgtcaaagac tgggattggt cttatgatgt accaaaccca tgggcaaatg
    12061 tttctgttac agcagattca cgttcataat cactaaaaat gaccgaaaaa gggcgatgtc
    12121 ctttttcggt tttttgatat ttttctgttt atttctctaa tattcaggtc aaggcgctga
    12181 tttcatgact tctccaataa acggtgttca aagtccagtt tctcggtatt aagtcaaatt
    12241 tatgcaaaaa tatggaaagc cattttcaca aaattttttc ttcatactcg aaactaaacg
    12301 aatttttcac aacttctcgt caatcactag gattattaaa gctttactta ccttttgacc
    12361 gaaccatttc aaatttgaca aaaaaccagt ataataagga agtatcgaaa aaatatccat
    12421 aaaaggaatg tggaaaatgg acaaccagct gacaaaagaa ctaaaagaaa actataacat
    12481 cgtttttcac gatctaaatt tgcttgaaca agcttttacc cattcatcct atgtgaatga
    12541 gcatcgcaat ctgcaattat cggataatga gcgacttgaa tttttaggag atgccgtttt
    12601 agaactgatg gtttctcagt atttattccg tttatatcct catttgccag aaggaaaatt
    12661 gacaaaaaca cgagctgcga tcgttcgcga agacagcttg tcgaaatttg ccaaagaatg
    12721 tcactttgat caatatgttt tgttgggcaa gggagaagag aattcaggag gacgtacgcg
    12781 accagcattg ctttgcgacc tattcgaagc ttttttaggc gcgttatatc ttgaccaggg
    12841 attcgacacg acccatgcat tcatcgaaaa agtgattttt cctaaagtca aagcaggtgc
    12901 tttttcacat gagatggatc ataaaacaaa actacaagaa gtcttgcaaa aatcaggtga
    12961 tgtatcaatc gaataccgat tgatcaatga agaaggtcca gctcatgaac gagtattttg
    13021 gatcgaagtt tatgtagatg atcaattgat tggcactgga caagggaaat cgaaaaaatt
    13081 agcagaacaa gctgcggcgg aaaatgcatt ggcagcactg taaaagtaag tgagggaaag
    13141 ctttgtattt gaaacgaatt gaaatagccg gttttaaatc atttgcagac aagacagtca
    13201 ttgattttga aaatagcgtc acagcagtgg ttggaccaaa tggcagcgga aaaagcaata
    13261 ttacagaggc tatccgctgg gtattaggag aacaatctgc taaaagtctg cgaggcggaa
    13321 aaatgccgga tatcatcttt gccggttccg atacccgtaa gcagctgaat attgcagaag
    13381 tcacagtgat tttagacaat agtgatcatt atctgccatt ggagtacaat gagatcagtg
    13441 taacccgccg ttatcgacgg actggggaaa gcgagttttt catcaataaa caaagctgca
    13501 gattaaaaga tatccaagaa ttgttcttag attctggatt aggaaaagaa tcgttctcaa
    13561 tcatttctca aggaaaagta gaagcgattt tcagtagtaa accggaagac cgtcgtggga
    13621 tctttgaaga agcagctggt gtcttgaaat acaagcagcg gaaaaagaaa gcagaacaga
    13681 agctttttga aacagaagac aacctcagcc gcgtccaaga catcatccac gaattggaag
    13741 aacagttaac tcctttggcc gcccagagtg aggcagcaaa ggagttttta cggctaaaag
    13801 aaacactgac tcaaaccgat gtctctttga tggttgctga aatcaagaca gcaaaaaaag
    13861 attgggacaa caaacaagca cagcttgcga aattcaatct agaattaggc aaactatctg
    13921 agtcgatcca agaacaagaa tccattttgg cgaagcagcg taaagaaaat gcgcaagccg
    13981 atcgtctgat cgaaaaaaat cagcaagtat tattagatct ttcggaaaaa ctgaagcaga
    14041 cagaaggaca aaaagatgtt ttgcaggagc ggacaaagca tacacaaaaa agctcgcaag
    14101 aatatcaaac ttcattagca gaagcacaaa aaaaggttaa acattttgaa aagcttcaag
    14161 aaagcttgat gaaagcagca gcagaaaaag aaacagagat ccaaaaagct gaagcaaatc
    14221 tcataaaaac acagcaagaa ttagaaaaat accaaaaatc aacgaaagaa ttattggcag
    14281 aattaagaga tcaatatgtt gatttgatgc aagaacaagc agctgtagga aacgaactga
    14341 agtatctaga acgtcaatat atacaagaaa cagcaaaaag caagcagacg ttagccaagc
    14401 aatcggaagt agaagcatca gtagaccgat tgatcttaca aaaagaagaa ttgacacaaa
    14461 agcaggcgca gctaaaatca tctttaactg aaacaaaaga gaagttagaa atgatccaac
    14521 aaaacgggaa aaagttccaa gaagcattag caaaagaaca gcctaaaatg tatcaattaa
    14581 tgaatcaagt ccagcagcta cgtgctcgta agaaaagcct tcaagaaatc caagaaaact
    14641 attttggttt ttaccaaggg gttcgattgg tcttgcagca taaacagcag ctttcgggta
    14701 ttgtcggagc agtggctgaa ctgatcgatg ttcctgcaga tttcacgtta gctatcgaag
    14761 cagctttagg tggggcagcc cagcatgtca tcgttgaaaa tgaaaaagat gctcggcaag
    14821 ccatcacgta tttgaaacag caaagaggag gaagagcaac attccttcca ctgacgacaa
    14881 tcaaaccaag acaattaccg gctcatatat tgacacaagc agcagctgta gaagggttta
    14941 tagggattgc cagtgaacaa gtcagttatc ccgatcaaat ccaaactgtg gttcaaaacc
    15001 tgctaggaac gatcctttta gccaaagact taactagtgc caatgcaatc gcgcaaacga
    15061 tccgctatca atatcgagtg gtttccttag aaggtgatgt gatgaatgcc ggaggatcca
    15121 tgacaggtgg agcgaataaa cgaggaaacc aaggcagttt gtttgtacaa aatcaagaat
    15181 tgaaacagtt gactagtgaa tttgaagaag cagataaaca actccaagca caagaaaaaa
    15241 aagttcagga gctgcaacaa gaaacagctc gtttagccga agaacaagaa gttttgcgta
    15301 cacgaggcga acaattacgt tttgaagaac aagaagcgac aaatcagcta caaaacatca
    15361 taaatgaact tgaacgtttt gaaaaagaaa agcaaatctc aacttttgag acacgtgaac
    15421 tgcagcagtt tatcgaagat tacgaaaagc aaacgaacga attgaaagac aaacaaacag
    15481 atcttgaatc gcaacgacaa aaaatcgacg aagaaatcaa atcgttaagt caagaaagcg
    15541 accagatgga agccagaaga gcacaagtac aaagtcaaaa agcacaagaa caagcagatc
    15601 ttgctgtctt gaaagagcag tttaatcatc tgcagatcca gctccgcggt gcccgagtcc
    15661 aaaaagcaga ggcaaccgaa cgtcaagaag cgatagaaaa gcagttggcg acattgacag
    15721 cagacttttc tgatcatgaa gtcacagaag aaagtttgga aaaacaaatt aacgaattat
    15781 ctgctcagcg agaaacatta aaagccgagt tggcaaaagc caaagagcag cgagatagaa
    15841 ggcaaaagga gatcgataag cttgaagcag tcttggcaga gcgtaatcgt gagcaaaaag
    15901 cacgactgtc ggaacaatcc aaattagaag tccaaaaaga ccgagctgaa atgattttag
    15961 ataatcattt gacctatctg cagtcagaat atcagctgac atttgagaaa gcttcccaag
    16021 actatcaaga aacaaccgat atcgaagaca gtagaacaaa ggtttcatcc ttaaaagaac
    16081 agattgaaaa actgggacca gtaaacttaa attcaatcga acaatacgaa caagtcagtg
    16141 aaagacatac attcttagca acacagcgag atgatctgtt agcagcgaaa aaccaattgt
    16201 ttgaaacgat ggatgagatg gatgatgaag tgcggacaag attcaaagaa gtatttgaag
    16261 ctatccgtca agaattcaaa attgtctttc caaatatgtt tggcggcggt aaagctgaat
    16321 tagtactgac ggaaccaact gatttgctga aaacaggtat tgagattgaa gtacaacctc
    16381 ctggcaaaaa actgcaaagt ctaagtttgc tttctggagg agaacgagca cttacagcca
    16441 tcgcgttgct cttttccatt atccgtgtct gtcctgttcc gttttgtatc ttagatgagg
    16501 tagaagcagc gttagatgaa gccaacgtga aacgttttgg tcgttacttg agcgatttcc
    16561 aagatgacac acaatttatc gtagtcacac accgcaaagg aacgatggtc gcagcagatg
    16621 tactgtacgg agtgacgatg caggaatccg gtgtatcaaa aatcgtttct gtacggatgg
    16681 aagatatcaa tgaagaggcg aaaatcaacg aaacgaaagt gtaggaacga aaatgatcaa
    16741 attagtagca atcgatttgg acggtacatt attaaatgaa caaaagctga tttcagatga
    16801 gaataaacaa gcattagcac aagcaaaaca gcaaggggtc aagatcgttc tatgtacagg
    16861 acgcccctta gctgcgatgg cgcattatct gcaagaatta ggactggtag atgaaggtga
    16921 ctacagcatc actttcaacg gcggtttggt acaaaaaaat gatactggtg aaatcatgga
    16981 aaagaaagtg atggaagtat cagatatcca acgcttatac aaactggctc agcaattgga
    17041 tctgccacta gatgttttgt ctgacaatgt ggttttacag ctgcctagtg ccccaaggaa
    17101 gcaatccttg tacaatgtgt tgaataagct gctgcaattc caaccagcgg atataagcga
    17161 tattacagat gaatttgtgc ttaataaggc agtaatcgct tatgaccaag aagaattaga
    17221 tcctaaaatc aaagaaatac cagcagaatt ccatgaaatg tatgagatca tcaaaacaag
    17281 aagtatgctt ttggaattta tgccaaaagg tgttacaaaa gcttatggta tttctttatt
    17341 ggcaaaagat cttggtttga aacaagaaga aatcatggcg atcggtgatg aggaaaatga
    17401 tttaccgatg atccaatatg ctggactagg cgtagcgatg gagaatgctg tgcctttcgt
    17461 caaagaagca gcagatttcg tgacagccag caatgaagaa aatggcgtag ccaaagtgat
    17521 ccaaaaattt gtattagagt agggggagtc aaatgggatt ttttgataaa atcaagcgtg
    17581 cttttactgg cgaagagaaa acagaagaag ttgaagtaca ggagaagtac gacaagggtt
    17641 tagaaaagac gcgtaaaaca tttggtgaac ggatgaatga gttgtttgcc aattttcgaa
    17701 cagtcgatga agactttttt gaagaattag aagaaacact tatcggtgca gatgtaggtt
    17761 ttgaaacagc gatacgaatc accgaagcat tacgtcaaga agtgaaactc agaaatgcga
    17821 aaaaatcggc agaagtccaa aatgcgatca tcgagaaact tgtggatctc tatgaagcgg
    17881 aaggaatcaa tgaagtaaat gaactaaata tccaagaaga cggactaaca gttattttgt
    17941 ttgtcggtgt taatggtgta gggaaaacaa caagtattgg taaacttgcc catcagttca
    18001 aaaacgaagg taaaaaagta ttgatggcag cagcagatac cttccgcgct ggagcaatcg
    18061 accagttagt tgtctggggc gaacgcgctg gtgttgaagt tgttcgtggc aatgcaggag
    18121 gcgatccagc agctgtcgta ttcgatgctt tggaaagagc aaagacagag caggcagatg
    18181 ttttactagt tgatactgca ggccgactgc aaaataaagt gaacttgatg aacgaattag
    18241 aaaaaataaa acgagtaatc cagcgggaat taccagaagc accccaagaa acacttcttg
    18301 tattagatgc aaccactggt caaaacgcga tggttcaagc aaaacaattc aaagaaacaa
    18361 cagatgtgac cggtcttgtt ttgacaaaat tagatggtac agcaaagggc ggtatcgtac
    18421 ttgctatccg taatgaattg catttaccag tgaaattggt cggtcttggt gaaggaatcg
    18481 atgacttgga gccgtttgat ccaaatgatt ttgtcgttgg attgttcaaa ggattactaa
    18541 aagaagaata acccatgtct aaaaagcagg agctgtgaca aaagttgcag ctccttgttt
    18601 gaatgattgt ttttaacata gctgtgtttt tgatgccttc atttttatac ttatttgtaa
    18661 gcggttctca aacaatttcg ttctttttct tagacttttt gattataatt agattcatat
    18721 gaattggagg tcacttaatg atgaatttta agcaattatt attgcatgtc aatgcgcgcc
    18781 cttttatcga ccaagctcga tttggtatag aacgggaagg acagcgggtt gatcttgcag
    18841 gaaatctagc aaaaaccgat catccagcaa tctttggcga tcgatcctat cacccctata
    18901 tccaaacaga ttttagcgaa acacaaacag agatgatcac ccctgttacc gattctattc
    18961 ccgaattatt tcagtatctc gctgctgttt atgatgtgac tgctcgttct ataccgaaag
    19021 aagagatgat ctggccatta agtatgccac ctgccttacc ggaaaaagac gaagagatca
    19081 ttattgcaaa attaaaaaat ttcgaagatg tcttgtatcg acgttattta gcaaaaaaat
    19141 acgggaagcg aaaacagatg gtaagcggta ttcatttcaa ttttgaattt ggcgatgagt
    19201 tgctaagaac attgttcagc catcaggaag aatttcaaga tttttccgaa ttcaaaacag
    19261 aactttattt gaaaacagcg agaaacttta tgcgctatcg ctggatgatc acttatttat
    19321 tcggtgcttc accaatgagt gagaagaact actttttaga tgaatcacat ccgcaagaac
    19381 ctgttcgcag tattcgcaac agtgcgctgg gctatacgaa tcatccaaat gtgaaagttt
    19441 cctatgcttc tatgaaacag tatttagcag atatcgagcg aatgatcgaa gaagggaaac
    19501 tttcggagga gaaagaattt tatacaccgc ttcgtttccg aggcggaaag aaagtcgcag
    19561 atttagcaac aacaggtgtt cgttatattg aattgcggaa tatcgatttg aatccttatg
    19621 caagattggg tatcaatcca gagcaagttc ggttcttaca attattcctg atgtacatgt
    19681 tatggacaga agaaaaagaa gactgtgacc aatgggtagc agaaggtacg actcgaaata
    19741 acaaagtagc actagaacaa ccatcagatc aaacagaatt tcatcaagaa ggtagagaaa
    19801 ttcttgaagg aatgaagcaa atgctggttg aattggattg gttggattct ctttatttag
    19861 tagaggaagc attgactcaa atggatcatc ctgaacaaac gttagcagcg aaactctatc
    19921 aagaagcaca gctatcgagt cagcaagaag ttgctgtggc attgggacat caatattata
    19981 aagaaagcca tgaacgtccc tatcagttgg ccggttttcg cgaaatggaa ctttctactc
    20041 agatatttat gttcgatgcc atccaaaaag gtgtccaagt caaagtatta gatgagtcgg
    20101 atcaattttt gcgtctgcaa ttccaagacc atgtagaata tgtgaaaaat gcaaacatga
    20161 caagtaagga cagctatatc gtcccactta tcatggaaaa caaaacagta acgaaaaaag
    20221 tcttaaaaga agctgggttc cgggtaccag gaggcgcaga attttcatcc atggaagaag
    20281 cggtaaaagc ttatccgaga tttgccgagc aggcatttgt gatcaaacct aaatcaacca
    20341 attacgggtt aggtatcacg attttcaagg aaggagctag tctggaagat tatcaagcag
    20401 gtttagccat tgcttttcgt gaagacagtt cggttttagt agaagaattt atgccgggaa
    20461 cggaatatcg tttctttgtg atcgacggag aagtccaagc catcatgttg cgagtccctg
    20521 ctaatgttat tggtgacagt atccgaacag tgaaagaact tgttgaagaa aaaaatagtg
    20581 accctttgcg tggaacgaat catcgtgcac ctttagaatt gatccaatta ggtgaattag
    20641 aacaattgat gttgaaagaa caagggttga cgatcgaatc agttccccaa gccaatcaaa
    20701 ttgtttatct aagggagaac tcaaatatca gtacaggtgg tgattcgatc gatatgactg
    20761 atgaattttc tgaagcttac aaaaaaatcg ccgtttctgc ggtagaagca ctaggagcta
    20821 agattagtgg tatcgatttg attataccag ataaagaaat cgatcctaca actgataaaa
    20881 aagcatatgg gatcatcgaa gcaaatttca atccagccat gcatatgcat gtttatcctt
    20941 ttgcaggaaa aggcagaaga ttgacgatga atgtattgaa attgttatat cctgaagtat
    21001 tttaaaagaa aaagcttttg acagattgtc ctatttgatg tcaatctgat caaaagcttt
    21061 ttttgcatgt aaaaatttat gtgttttttc gttttaaaat aaacgatccc agaagctttt
    21121 tttctttttt ggtttttctt tttcagctgg cgaagagttt tcttctgggt attttttttc
    21181 gatatcaatc acaggttcat ttactgcttc ttttgctgtt aagagcaatc cgaattcctc
    21241 aggatttgca gtgacgtaat cgttgactac agtgaaacgg ctattgtttt tcgttgctag
    21301 ctggatatat tggttttgga cagaaagggg tagagcccca ttcaagagta tggaagcatc
    21361 tggatgtttt ttgagttctt ttaaaaagtt ttctttgttt tttggttgga tcatttcagc
    21421 aacagtcata ctaagatagc agcgttccct gaatgtccct aaatatttat gctgttcttc
    21481 agggttcact aaaggtgtac cataaagtcc cttatccaaa tggcttttta catcatcttg
    21541 tgccataaaa aataccctcc ttcttctctt tgtctttctt acgattatag catattccca
    21601 ataataccta aaacatatga aaaagcggtt gcttttgttc aacgattcac ttaaaataag
    21661 aatgaaaatc attctcaatt agaaaggtgg attggatgcg ctacggacga ctagtagcat
    21721 tattagttat tttaagtagt atttcattgt tcatcggagt atcgaatgta caattgtcag
    21781 aactgctcca gttagatggg caaagcttac aaatcttgct agtgactcgt ttgccacgaa
    21841 cgatttgttt gatccttgtg ggagcgacca gtagtatttg tgggttgatc atgcaacatt
    21901 tgacccaaaa taaatttgtt tcaccaacga ctgcgggcac gatggatagt gcgcgtttag
    21961 gtattttagt ggctatgatt ttcctacctg gtgcatcctt gattgtccga tccttgacag
    22021 cattttgctt tgcttttgca ggaacattgc tttttttatc ccttacgcga ttgttcctcc
    22081 agaaaaatca attgatgctt ccgttgattg gagtcatgtt agggaatatc attggttcag
    22141 ttgctacttt ttttgcttat caattccagt tggtacaaaa tatgacttca tggcttcaag
    22201 ggaattttgc gactgtgata cgaggaaatt atgagttatt gtatgctgtt gttccattgt
    22261 tgctcttggt ttggctattt gcttaccgat ttacgatcat tggtctgggc gaatcgtttg
    22321 cagtaaatct gggaatagat taccagaaga tgcagttttt aggcattggc ttagtatcat
    22381 tggctagtgc agtcatgttg atcatggtag gaagcattcc ttttatcgga gtgatcattc
    22441 cgaatcttgt ctctagaata tatggagatc aagtgcacaa aacaattggc gtaactgctt
    22501 tagcaggtag tttgttctta gtattttgcg atcttgtcgc tcgcgtgttg atttttcctt
    22561 atgaaatacc agtcagtgtg atcgttggaa tcatcggtgg ggctatcttc ctttatcttc
    22621 tgataagggg acgacgatat gcttaaaaaa aagccatcta tttttattgg tatgcttgtt
    22681 cttgttttat ttgttacagg aatgtacttg acgatccata catatggaaa ctggcatttt
    22741 gcatgtgcat tgaggagtaa gaaaattttt gcatttatcc ttgtctcgct agctgtcagc
    22801 agtgccacaa tcagctttca gacaattacg cataaccagt ttttgactcc ttcagtattg
    22861 ggacttgagt cgttatatgt ccttgtccaa acggtccttt tcttctttat cggaggagtg
    22921 acgatgcttc agcagacagg tacagttttt ttcttattga acgttgggct gatggtcggg
    22981 ctgagtctat tgttattttt ctttcttttg aaaaaaatga gagcgaatct ttttttatta
    23041 ctgatgtcag ggatgatttt aggtacgctt tttggtagtg tcagtacctt tttacaagtc
    23101 atcatggatc cgaatgaata tgatttgctt caaggcagat tatttgcaag ctttggcaat
    23161 atccagagtc agtatctttt gcctgcttct ttgatcatta tcggctgctg gtacctgtta
    23221 tttcgatatc gacatgtgct agacgttttc catctcggaa atgaacaagc agtaaacctc
    23281 gggatagaca cagatcgttt tgaatttttg attttatgtt gtgtcagtct tttgacaggg
    23341 acatcaacgg ctcttgtggg tccagttact tttttagggt ttattgtcgc aaatatcagt
    23401 tatcgtgtct tttctactta tcgtcatggt cagctattta tcggaagctt tctggtagct
    23461 atgctgtttc tgacaggagg acagctcgca gtagagcaga ttttcggctg gaatacaaca
    23521 gtgagtgtcg tcgttgaatt tgtcggagga atttattttg tcacaaaatt gattcgcgaa
    23581 aggaagagta tcctatgatt gatttacaaa aggtcaataa actgtaccat ggaaaatcag
    23641 tggttaaaga tgtacagtta acgattcctg aaaagaagtt gactgctttt atcggtccaa
    23701 atggtgctgg aaagtcaacg gtgttgtcga tgatcagtcg tttgatacca aaagatacag
    23761 gtgaaatcta tttagaccat aacgaagtaa aggcttggaa atccaatgaa ttagccaaaa
    23821 aattatcgat cctacgacaa tcgaatgaaa taaatgtcca aatcaccgtg aaagaattag
    23881 tagaatttgg acgatttcct tatacgaaag gaaaattgac gacaaaagac gaggaaatcg
    23941 ttcaggaatc actggaacac cttgggttag aagaaatagc ggatcaatcg attgacactc
    24001 tttcaggcgg tcaactccaa cgtgcgtata ttgcaatggt gctagcgcaa gacacggatt
    24061 atattttact ggatgaacct ttgaacaatc tagatatgaa ttttgcggtt caaatcatgc
    24121 agattttaaa aaatttagta caagaaatcg ggaaaacaat tgttattgtt cttcatgata
    24181 tcaactttgc tgcaagttat gcagacgaaa ttgttgcaat gaaagatgga cagttattta
    24241 cgcaaggaac gacccaagaa atgataaaaa aagatgtatt ggatgaatta tacgaaatgg
    24301 acatacggat ttgtgagatt gaaggccgca gattctgtct ttatttctaa aactaacatt
    24361 aggagagaag agatgaaaaa attagtagta ggtatcttga ttctagcatc atttggttta
    24421 gcagcatgtg gaaatagcaa caacaccagt caggcagaca caaaaaaaag cagcacacaa
    24481 actgaaacta cattgacgat aacagatagt aatggagacc aaatcgaggt gccaaataat
    24541 ccagaaaaag tcgtcgtatt cgacaatggt tctttagata cgatggatgc tcttggtgtt
    24601 ggagataagg tagttggagc agctacaagc agccttcctg agtatctttc atcctataaa
    24661 aaagtagaat cagcaggtgg aataaaagaa ccagacttag aaaaaattaa tcagcttcag
    24721 ccagatctaa tcatcatttc tggccgacaa agagattttc aaaaagatct aagtcaaatt
    24781 gctccgacca ttttcctttc tttagatgcg aaaaatccat gggaatcttt ccagcaaaat
    24841 gtcactgctt taggggagat ctttggtaag caagaagaag ctaaaactca attagaggaa
    24901 ttatctagtg caatcgatca gacgaaaaag aaagcagaag ctactgacaa aaaagcacta
    24961 gtcacacttg tgaatgaagg gcaattatca gcctacggat ctggttctag attcggtttc
    25021 atccatgatt tatttggctt tgaacaagca gatgatcaaa tcgaagcatc cactcacggt
    25081 caaagtgttt cttatgaata tgtgctggaa aaaaatccgg atatcttatt tgtagtagac
    25141 agaacaaaag ctattggtgg agacgacagc aaagatgata tttctgccaa tgaactggta
    25201 gcacaaacga atgctggtaa aaatcagcag atcatctccc ttgaaccaga tgtctggtat
    25261 ttaagcgggg gcggtttaga atcaatgaaa ctgatgatcg aagatgtgaa tcaagcattt
    25321 aaatagcata aataacagag gattaaactc tcatactatg taacaataat gtttcttaca
    25381 ttcttaaata gcaagagcct atcctcaaag aagttatcaa aaaccatccg taaaatcgta
    25441 ttgatgattt tacggatggt ttttatttat ttgagaaatc ttttttcaac gtgaattcat
    25501 tatctacatc atacgggttg attctagaat ggggagtggc aaaaaatagt gtgatccatt
    25561 ttttcagcat caagatcgcc tcctttgatt tgaatcaaag gtacaaagcg aaacttagat
    25621 aaaacttaaa tttagatatt tttattttgt accgatctct tctttaaacg atgttccatc
    25681 tgctgcttct cggcaataag tccactagac tagaaaatat gagaagctat tttctgtcca
    25741 gcgttcttat tactcaaaac aaatcgcagt tgtcacaatc tcttctaaac gatgttccat
    25801 ctgctgcttc tcggcaataa gcccactaga ctagaaaata tgagaagcta ttttctgtcc
    25861 agcgttctta ttactcaaag caaatcgcag ttgtcacaat ctcttctaaa caatgttcaa
    25921 tcagctgacc ttcggtatta gctcaaagca ctgatttcac aacctctatt taggcatgtg
    25981 tctcagcaag cggttgatag ttgatgatct gcatttttcg ataaaaatcg gcgggaagct
    26041 tactccaccg ttttagtaat tgatagaaat aactctcttc tgctttgatt ttatactcgc
    26101 ttaatatcaa tccaaaacta ttcgtttttt ttgaagctaa ttttttataa atatccaatg
    26161 ctttggtttt atcttcattg acaaagagtg tttttacttc aatataagaa ccctcgatat
    26221 tttgtgtttc ttcgataaaa tagatgtttt ttatatattc cttcatagtg attcctccaa
    26281 agaagtcttt tatttgataa gtttactcta ccgaagagtt gttaataatc cgtgaacaaa
    26341 aagtaattct ttttccaata gttgttaaag gttttttatt ttttatagta ttttttgtta
    26401 tttaagaaag gaataaggtt aaacaaataa caggttgctt tttgggtctt tttccgttca
    26461 agaaactgaa cgaagaaaag ggaaagttgt ctcttttgtg ataagagaaa tcataataaa
    26521 cgaatgactt actttccaat aaattgagaa cagtcagaac cagacaaatt agttgcatct
    26581 gatgaataaa gtgattattc tatgacatga ggtgatacag atgaaattag aagtgacaaa
    26641 agaagcacaa gaagtattga agaataaatt agaagcagac gatcaacttt tattagatat
    26701 cgaaaacggt gacggtccat ttgcagaaag ccaagtcagt tgccaattgg atacggcatt
    26761 tcgattgatc attgtcaaaa aagatacaca aacagatcta agtctttatt ctgtagtggc
    26821 tgatacacca gttggaccaa tcaaaatcaa agacagtgca atactttaca tggatgatcc
    26881 atccacactt gctttagaac caacttataa tagtttacaa ttaaaaggac caagcggctt
    26941 gagaaaaggc aacttgcaag ttgttcgaaa agactagagg gataaaatgg gaaaattggc
    27001 gatcatcagc gacctacatg tggacatcaa taaattcggc gaatcagagc tgatgcagct
    27061 ttggcaagtt ttgcaaaagc acaagatcac tcggcttcat ctagccggag atacggctaa
    27121 taaagtagac cgttgcctag ctgttgtcga atttttcgtc aataaaggat tatctacgac
    27181 atttcatttc ggcaatcacg agttggcaga tgtgcccaat gaacagatga tggaccattt
    27241 tccagaccca cattttttaa atgaacggta tattgcttta aatgagcaga ccgttctttt
    27301 agggatgaat ggctggtacg actatcagtt ttccgaattg aaagattacg aggcaatcgt
    27361 acgaatgaag cgtttgtatt ggtatgatcg gttcatccag cgtgggaaaa cagatctcga
    27421 ggtcaatgca gaaatgcttg cagctgcaaa aaatttgcta gaccagctgg aagcaaaaaa
    27481 acttgaggtg attttatcca ctcatttcgt tcctaaacgg gcatttatca tgtatcaatc
    27541 tgctccttat gagcgttgga acaaattaaa tgcattttta ggatcagaat cattcggaga
    27601 attacttgac cgttattcaa atatcaaaca agtagttttt ggccatacgc atcgtcgctt
    27661 tgaagataaa tccatcggtc acacgattta cagctgcaga ccttttggtt attattatga
    27721 atggcagctg acccgagatt ttgtcttgaa agaacagttg ctagacagct atgatcctat
    27781 gaaattacgt gtcctcttgc gtgcccatca cccagctttt caggcctatc aaacacaaca
    27841 tttgcaagag gaatttgaac aagcgatgac aatcgttccg tattgagaca gcattagtaa
    27901 tgtgtaaaag aaaatacctt gtaaaacata aggataagta agagcagtag atccatttat
    27961 cgtggatatg ctgctttttt tgcggaaaat aatcagcgaa tgtttatttg atcggatgat
    28021 ttgtaactcg cagagtacta gatgcaagcg tgtattcttt ttttgaacga taatcacaaa
    28081 aaaaaatata atatacattt tttatttaat tataattaat attgattgaa gtctaggcag
    28141 tcaagtcaca ttttgataga taggaggggg acttacgaat tattttaaag gctatgacag
    28201 ctgtatttct agattgtgtt tgcatcaagt tgcaataaaa actagaaatc aaatcgggct
    28261 gataatcatt tataactaat cgatacatag gaccaaatat aggtctatgt tcttttattt
    28321 cataagtatc gtaaaacaga attttgctat ggattaatcc aatcgactga tatgtttagt
    28381 aaataaagaa agaggaatgt caatgatgaa aaaagaaatc gtattaacag cagcaatgat
    28441 gttattcagc atggtagcaa gtacgacttt tgtttctgca actgaagtat acccaaagga
    28501 atataacaca gaaggaacga ttacatttga agcaggagat gagggtgtaa ctcctcctgt
    28561 tgatccagag aatcctgatc ccaataaacc tgtcgatcca tcagatcctc caagccctgg
    28621 aacaggaggg gcattatcga ttgattatgg atcaaaattc aaatttggga ctcaaaaaat
    28681 ttctactgcg gataaaacgt attatgcagc tgctgatgtg atgaacgatg ggtctagaaa
    28741 accgacatat gtccaagtga cagataggag aagtacctta tctgggtgga aattaagtgt
    28801 ctctcaacca gaacagttta aaactgccag tggggatgaa ctagttggag cacagctgaa
    28861 atttacgaaa gggcaggctg tttctttggt tgatccaaca tatacgccgc aaacggtgaa
    28921 ttctgaatta acgttgacac cgggaggaaa caatacgtta gcaattaatg ctaaatcagg
    28981 aacaggtgtg gggacttggg tctatcgatt tggtgcaaat gaaaatgaaa atcaagatgc
    29041 ggtacagctt tcggtacccg gtaaatctgt caagttagcg caacaatatt ccactaaatt
    29101 agtttggaca ttagaagata cacctaacaa ctagtttact gaaaagaact gttaaaaata
    29161 aatacgtagt catattgtct tgcgaggtaa tcgagcaaaa attgtcaaag gctaggctaa
    29221 atttgtttgg atacgaatag ttcatctagg aatttaacga tcaggaggaa aagatatatt
    29281 gaaaaagagg aggatcgtgc tcattttaag cagtctctta gtgactaata tctttccgat
    29341 catagggtac tctttggaat tgaatcagtt ggagcatgga aatagaagag acgaagaaag
    29401 caaactcact tcgacattcg acagtttaat agaatccaac cagacacaag aaagcagtga
    29461 ggatttaagt atttcgagta gtggagagac cactgacaac gtagaagctg agggttcgga
    29521 caaacaagga ctagaagatg caccaatttc tgcggttgag ctgcctgacg atcccaatat
    29581 tatttctatc gataaaattt ttcaaacacc tatcggtact agcacgtcca tattggaaaa
    29641 tgggaagtta ctgcagttga acccagcaga aaggtctcaa agaggagcta tttggtcaaa
    29701 taagaagatt agtttactct cggattttac atttaaatct tatttatact taggaaatca
    29761 acgagataga gcgggagatg gcatgacctt tacattgact ggcgatccta gaatggctag
    29821 taatcccagt caagttattg gatcgccagg tatgggaatt ggctcatatt ctactcgttc
    29881 tggccaacct tacattgcga atgcgctctc gattgagttt gatacgtata aaaatagtgg
    29941 ttcttctgat cgaatggatc gagagataac tgctgataat agagggcatg gacatgtcgc
    30001 ttttgtcacg cctaaaccaa ataataataa ttattctgga gagcatactg gcgtgacggt
    30061 agctcctaca tttctttcta atggcacatg gcgcttgtta ataattaaat gggacgcgga
    30121 gcaaagaagt cttacttatg atttggaagg tgtcggtcgc tcttctcgga ttatacctga
    30181 tctcattagg cagtttggtt ctacagaagt aaattggggg tttacttctt caacaggtac
    30241 tttttttcaa gaaaatgctg tcgctgtcac gcgacttcca tcgaatgtca catcaacagc
    30301 tgatgtaaaa gtcaacgata gtgattatgg ggccatcgct gaagctggag gaaacgataa
    30361 gataactatc agaaatacat tgaaggtcga gggggatttt cttgaatata agaaaatgca
    30421 gactagtatc gacctcccac aagaattaac tattcccgag catatcttga tcaatggaaa
    30481 tcaaattgat gccaaagata tcttgataac cggaaatcga gtcacgctaa atctgacaga
    30541 ttattttatt gctggagata cgttaataat cgaattggag acaactttgc aggaagtaat
    30601 tcctgaaaaa gtactcacta tgcattttga ataccttgaa aacgggaatt tgattgagca
    30661 atcgaatgaa ataaacctaa agatcgcaaa gctgaaggag atagatatcc atgtttatta
    30721 taaagataaa gacagtcaga ttgatattgc tgaaatgaaa acaatcactg ggaaaatagg
    30781 agagaagtat aaagaaactc ctattgatat tgaagggtat gtttttgact cggattcagc
    30841 gaatacagaa ggcatcttct ccgaaaatac agaggatatc tatttttatt acagaaaagg
    30901 caaactttat ctctcaactg ctcctcaata tgtcaatttt ggaaaacata aaatatccag
    30961 tagaccatta agtgaattcg gacagttttc aggtgggttg aaaattatag atgaacgggc
    31021 ttttggaagt tggaaattac aattgaaaca agagaaagtt cttacaaatg gagattttga
    31081 gcttccagaa gctctttcct ttgttacctc tgaaaataca acggttatag ggacatccgc
    31141 tgttacgatt ttcgaaagtg atcaaaaggg tgaaagcgat ttgtcctctc ttttagattc
    31201 tacagctcat cgtggaatca gaataaatat tcctgtagaa aaccaaagaa tcggaacctt
    31261 tgaggggaaa ctatcttgga tacttgcaga tgtcccagga aattaacagg aagagaagaa
    31321 tataacaaaa ttattgagtt tcaagaaggg cacaggtacc ataggctctt gtgtcccaca
    31381 gagacaagat tttgttatag tcttctctta catatgatta aaggagcgat tttcttgaga
    31441 ccaaaacaac aattatttat aacactccta gttattttag gggcactttt taacaatata
    31501 tcagtgtcag ctagtgcatt taatttttca gtgacgccga taacttcaga gaatcaaatc
    31561 gacaagagaa aaacttactt cgatcttcaa cttgatccgg atcaggaagt agaagtaaaa
    31621 gcggaattga gaaatgatac agaaaaagaa gtgaaaatcg atatttctgt gaatagcgca
    31681 accaccaatt caaatgtgat ggttgaatac ggaaaaaacg agattgaaaa agacatgagc
    31741 ctgatctttg atctggtaga ttatgtgagc tatccacaga tagtgacgct aaaacctaaa
    31801 agtgtccaaa ccgttgcttt tcatgtcagg atgccgaatg agcgatttga tggtgtattg
    31861 gctggtggga tcacattcca agaaatccag acggaaaagg accaaacaga aactaaggat
    31921 caaagcttat cgattgagaa tgaatacacc tatattattg ctttgttgat gcaacagaca
    31981 ctgaacgaag ttgctccgaa ccttactctt catgaagtta aaccagatca aatcaatgca
    32041 agaaatgtca tcttagcaaa cgttcaaaat gatcaaaaaa cctatatcaa tcaagtagtt
    32101 attgaaacaa aaattacaaa aaaaggacat tctgaagttt tatatcaaga ggaaaaagaa
    32161 ggattgcaga ttgcgccgaa tacaaatttt tcttttccaa ctgctttaaa tggtcaaccg
    32221 ctaaccccag gtgaatatca ccttacaatg actgttttag gaaatgaaaa tgaaaatgga
    32281 aaattttcga gaaaaaaagg aaatactacg atcaactata ccaatcaatg ggtatttgaa
    32341 aaagatttta caatagacgg aaaagtagcc aaggaattga acacgacgga tgttacgatt
    32401 aaaaaagaca ataattggat ttatatctta gtagcttcac ttttcttatt gtttatttta
    32461 ttatgcatac ttttgtttgt tttgagaaaa aaagaagaga aagaaaagta aggttaagat
    32521 aacaaatagt aaatttttat tattgtagga tggttgggct ctttttataa caatataaaa
    32581 tataccattt tattaataaa aatgcatact agtaaatgat ataattctaa taacaggttt
    32641 gatcgcgaga aaggccaaat aaaacgctct ccaaaatgtt aaaaaaaaga caggacgatg
    32701 tatattatac aaacaagaat cgctgacaac agtgactcgg atccaggaaa tcagttttat
    32761 ccccagctag ttggtgaatg catggaaagt aatatacgta gaaagagctg atgactaatg
    32821 aattatgagt tttttttaag caaagaagat cacagaagtt attcattact taaatattta
    32881 gaagcaagct caaatttatc agagtcaata tcgaatgttc aagaagagtt gtcgctatcg
    32941 acatttctct tgaaaaaaac gatcgataag ctgaaacatg atttacaaaa gttcgatcta
    33001 gagaaaaatt tgcgagtaac cgtcagtgaa ttggatatat gtctggaaat taatggaaaa
    33061 tgttctagca aagctctgtt atctcgttat ataacggatt ctttatctat gaaaatggta
    33121 ttggctttct ttcaggaaaa atatatctca gtagaaaatt ttgctaaaca gcatcacgtg
    33181 agttattctg tggcttataa agtattacaa agactaaaaa gaaatctaaa aaaatatcaa
    33241 attttttttg aaaagagaaa gtt
//
LOCUS       DADGKS010000025        31330 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.025, whole genome shotgun sequence.
ACCESSION   DADGKS010000025 DADGKS010000000
VERSION     DADGKS010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31330
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.025"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(547..909)
                     /locus_tag="JXV47_001304"
     CDS             complement(547..909)
                     /locus_tag="JXV47_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487358.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(983..1363)
                     /locus_tag="JXV47_001305"
     CDS             complement(983..1363)
                     /locus_tag="JXV47_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HAX1487359.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1445..2620
                     /locus_tag="JXV47_001306"
     CDS             1445..2620
                     /locus_tag="JXV47_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAX1487360.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            complement(2697..3281)
                     /locus_tag="JXV47_001307"
     CDS             complement(2697..3281)
                     /locus_tag="JXV47_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAX1487361.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            3482..4480
                     /locus_tag="JXV47_001308"
     CDS             3482..4480
                     /locus_tag="JXV47_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAX1487362.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            4592..5101
                     /locus_tag="JXV47_001309"
     CDS             4592..5101
                     /locus_tag="JXV47_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HAX1487363.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(5131..5790)
                     /locus_tag="JXV47_001310"
     CDS             complement(5131..5790)
                     /locus_tag="JXV47_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HAX1487364.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(5792..6556)
                     /locus_tag="JXV47_001311"
     CDS             complement(5792..6556)
                     /locus_tag="JXV47_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HAX1487365.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(6564..7241)
                     /locus_tag="JXV47_001312"
     CDS             complement(6564..7241)
                     /locus_tag="JXV47_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HAX1487366.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(7278..8663)
                     /locus_tag="JXV47_001313"
     CDS             complement(7278..8663)
                     /locus_tag="JXV47_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HAX1487367.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(8873..8957)
                     /gene="ffs"
                     /locus_tag="JXV47_001314"
     ncRNA           complement(8873..8957)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="JXV47_001314"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(8980..9495)
                     /gene="tadA"
                     /locus_tag="JXV47_001315"
     CDS             complement(8980..9495)
                     /gene="tadA"
                     /locus_tag="JXV47_001315"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HAX1487368.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            9602..10459
                     /locus_tag="JXV47_001316"
     CDS             9602..10459
                     /locus_tag="JXV47_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HAX1487369.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(10540..10875)
                     /locus_tag="JXV47_001317"
     CDS             complement(10540..10875)
                     /locus_tag="JXV47_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487370.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(10942..12312)
                     /locus_tag="JXV47_001318"
     CDS             complement(10942..12312)
                     /locus_tag="JXV47_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NOL1/NOP2/sun family putative RNA methylase"
                     /protein_id="HAX1487371.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(12390..12926)
                     /locus_tag="JXV47_001319"
     CDS             complement(12390..12926)
                     /locus_tag="JXV47_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAX1487372.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            13235..14716
                     /locus_tag="JXV47_001320"
     CDS             13235..14716
                     /locus_tag="JXV47_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAX1487373.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLIKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            complement(14819..15526)
                     /locus_tag="JXV47_001321"
     CDS             complement(14819..15526)
                     /locus_tag="JXV47_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HAX1487374.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(15605..15943)
                     /locus_tag="JXV47_001322"
     CDS             complement(15605..15943)
                     /locus_tag="JXV47_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HAX1487375.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(16054..17016)
                     /locus_tag="JXV47_001323"
     CDS             complement(16054..17016)
                     /locus_tag="JXV47_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HAX1487376.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(17031..18362)
                     /locus_tag="JXV47_001324"
     CDS             complement(17031..18362)
                     /locus_tag="JXV47_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAX1487377.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(18370..19050)
                     /locus_tag="JXV47_001325"
     CDS             complement(18370..19050)
                     /locus_tag="JXV47_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HAX1487378.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(19269..19748)
                     /locus_tag="JXV47_001326"
     CDS             complement(19269..19748)
                     /locus_tag="JXV47_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HAX1487379.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            complement(19875..21554)
                     /locus_tag="JXV47_001327"
     CDS             complement(19875..21554)
                     /locus_tag="JXV47_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAX1487380.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            22102..23604
                     /locus_tag="JXV47_001328"
     CDS             22102..23604
                     /locus_tag="JXV47_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1487381.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            23617..24279
                     /locus_tag="JXV47_001329"
     CDS             23617..24279
                     /locus_tag="JXV47_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1487382.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(24380..24583)
                     /locus_tag="JXV47_001330"
     CDS             complement(24380..24583)
                     /locus_tag="JXV47_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAX1487383.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(24694..25878)
                     /gene="iadA"
                     /locus_tag="JXV47_001331"
     CDS             complement(24694..25878)
                     /gene="iadA"
                     /locus_tag="JXV47_001331"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HAX1487384.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(26035..27774)
                     /gene="yfcC"
                     /locus_tag="JXV47_001332"
     CDS             complement(26035..27774)
                     /gene="yfcC"
                     /locus_tag="JXV47_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HAX1487385.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            complement(28547..29161)
                     /locus_tag="JXV47_001333"
     CDS             complement(28547..29161)
                     /locus_tag="JXV47_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAX1487386.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(29767..30144)
                     /locus_tag="JXV47_001334"
     CDS             complement(29767..30144)
                     /locus_tag="JXV47_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487387.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(30444..31325)
                     /gene="galU"
                     /locus_tag="JXV47_001335"
     CDS             complement(30444..31325)
                     /gene="galU"
                     /locus_tag="JXV47_001335"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAX1487388.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
BASE COUNT         9335 a         6500 c         5225 g        10270 t
ORIGIN      
        1 gagtgtttcc cgattcgttt ttggctgccg tagcaacttt tatatcatat cagagagaca
       61 agcgattgtc aactcttttt taaaagtttt tttcgatttc gtttttcgaa atctttcagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcgt
      241 tagtaacatg tcaataacta ttttttaaat tttttagaaa tgtgatataa catccacttc
      301 agaatcaacg ctgttaaatt tatcatgtat ttcttccttg gtcaactata aattaagcat
      361 tactttgtga aatgattttt cgatcaatta ttattattcg ttatacaacc gttttcaaca
      421 tattttgaaa ataaaatgca ctaaaaaact atctttagca gaacatttca ttgtattttt
      481 tggaccaaac aataaaaaaa gaagtttgaa aaaaattcaa acttctttgt tcgcttaatc
      541 tgtattttag aagaaaggca ctccctctac ttcgtaagtt ccaagaacag agcgcatttg
      601 acctggttct tcccaaatat atccttcgcc taattcttct ctttgattct tttgttcagt
      661 ttcaaagaca aacaacggaa cattttcctc tttaatatgt gtatttgtca attccatcaa
      721 actaatcttg ctaacatcga tatgaactat ttcttttaag aaattaagta tattcgctaa
      781 accagtcttt ccttcagaaa gttccgctaa cgcaaattcc aacttgtcat caattgaatg
      841 gaccaaaaat tttttagtac catcctccaa atgcaacata attgtaccag caactctttt
      901 gcttgccaaa atttccacct cgatcaactt gttctatggc ttacataaaa attctagcac
      961 attttcagaa aaaatacact ttttatttct tattttcttt ccgttctagt tcagataatg
     1021 cttcttctat ccaaataggt aactgctccg caatagtggt aaatccgatc ttacgatttt
     1081 tattcgtgaa ataccttttt ctgcgatatg gaacagctgg atttgttttt tctaacgttc
     1141 ttaaagataa actgattttt ttggaatatt catcaatgtc gatgatctga actgttactg
     1201 gctgtccgac ttttaacaat gaatggatat ttttcgtata accggattgt acttctgaaa
     1261 catgaataag tccttgcgtc tcgttatcaa gagaaacgaa tgcgccataa ggctgtatcc
     1321 ctgtcacttt tccttcaatt atttgtccaa ttttataagt catctacttc cctctcttcg
     1381 catttatcat tatactgtaa atagctcaaa aaaagaagcg acgaaaatga ctggaggtct
     1441 taagatgatc gaatttgata aacagatttc aagaaaagat acagaaagtg taaaatggga
     1501 cgcaattgct gagacatatc aaatggatga cttacttcct ttgtgggtag cagatatgga
     1561 cttcttgtct cccggtgggg tagctaaagc gtttagtgaa tacatcaaac atggaatctt
     1621 tggttatgcc actctgtctg ataaactata tcaggctatc attcattggg aacgccaaca
     1681 ccatgctgtg gagttgacga aagaaaatat cgtttttaca agtggtgtgt taaccagttt
     1741 agctgcagca gtacaaactt ttacaaaacc aggcgattct attttgattc atgacccagt
     1801 ttatcctcca ttttcctcta ttatagaaac aaatcaacgt cacatcgttc gaagctcttt
     1861 gctagaaaaa aataatcatt tcatcatgga cttgtctgac atggagaaaa aaatcgaaga
     1921 aaacaatgta aaagcaatga ttttatgcaa tcctcacaat cctggagggc gtgtttggag
     1981 caaagaagaa ttgaaacagt taagcgaatt gtgtttaaaa catcaagtga ttctgtttag
     2041 tgacgagatc catcaagatt taactttatt cgatcataca tttacttcca tgctaacgat
     2101 tgatcctaat ttagatgatc tactagttgc ttttacttcc gcaaccaaga ctttcaatct
     2161 agctgcaatc aaaaattcaa tggtatttat caaaaatcca gagatgaaag ctgattttga
     2221 aaaacattta gtgatgaacc aacagcacga aatcaacact tttggactga ttggaaccca
     2281 agcggcttat gagacgggtg gagaatggtt aagccaactg attccttatc tagaaaaaaa
     2341 tgttcaaaca gttaatcagt tttttgaaca gtatcttccg aaagtgagaa taatgaaccc
     2401 tgaaggaact tacttaatgt ggttagattt taccgcctat atttcagacg accaagaatt
     2461 ggagaacact cttgttcgga aaggaaaagt cgtattaaat cctggcatca cgtttggtcc
     2521 ttccggtcat gggcatatgc gcttgaatat tgcttgtcca gaagaaactt tactggaagg
     2581 acttaatcga atcaagtatg ctttagagac aatcgattaa atcatttatt caaaataaaa
     2641 ggacgagacc ttactaggtt tcgtcctttt tcataattac tccgtaccat accaaactat
     2701 tctgaaattt caattgtttc aatcactaca tcatgtacag gtcggtcttg tggaccacgt
     2761 tgtacatttg cgatttcatc tactgtgtcc atcccttcta gtacatgtcc aaagactgta
     2821 tgtcggaaat ctagccaagg agttccgcca cctttatacg cttcaatgat ttctgatggg
     2881 aatccagcac cttctagttg tccaagcata ttagctggca catttgtgtt atttacaata
     2941 aagaattggc ttccgtttgt gtttggacct gaatttgcca tagataaagc tccgcgaagg
     3001 ttgaacagtt cacgactgaa ttcatcttca aaactttcgc cataaatact ttcgccaccc
     3061 attcctgttc cagttggatc gccgccttgg atcatgaaat caggaataac gcggtgaaaa
     3121 atcacgccat cataataacc ttttttggaa agttcaatga aattttgaac cgtcttcggt
     3181 gctagttcag ggaataattg aacagtaatg tcaccacggt ttgttttgat aacagctttt
     3241 ggtccttttt cactttttaa atctagttgt gggaatgcca tattgtttcc tcctaatatt
     3301 tgcatacttc ataataataa taacataata cctaacctct cgtaaaaata ctagatttgt
     3361 tttcttttat ttttcatcac tagatacatt ctataactta ccgtttcgat ttcgaattca
     3421 aacatttttg agaagcattc tcaattaaat tctgatatag tgtgaaaagg gaggaatttt
     3481 tatggaaatc tatgacatta caatcatcgg tgcaggtcct gtagggatgt ttgccgcttt
     3541 ttacgcagga atgcgccaag ctaaaacaaa aatcattgac agtctacctc aacttggtgg
     3601 tcaattagca actttgtatc ccgaaaaata tatttacgat attcctgggt atccagcaat
     3661 aaaagcaagt gaattaatcg atcaattaga aaaacaatta actactttta accatacatt
     3721 ccatttaaaa gaagaagttc tctcgcttac tcgtgaagac gaagttatcg agattactac
     3781 aaataaaggc atccattatt ccaaagcagt cattttagct ttaggaaatg gttcattcca
     3841 gccaagaaaa ttgaatttag ataatgctga atcatttgaa aaccacggat tggattattt
     3901 cgtgaatgat ttgatgaagt atgctggaaa aaaagtcgct attgctggag gtggtgattc
     3961 tgctatcgat tggacgttga tgttagagcc tattgcaagc gaagtttact tgattcatcg
     4021 tcgcccggaa tttcgtgcgc acgaacatag tgtatcacgc ttgaaatctt catctgtcaa
     4081 cttgcttact ccctatctca tcgatggatt atcaggcaat aatggggaac tgacagatat
     4141 ccggttaaaa aaagtgaaaa gtgacgagac gattgatttg atgattgatt ctctgatcgt
     4201 caattatgga ttctcttcta atttagaaca tctttcttct tggggacttg atagtaccag
     4261 aaatgccatt actgtaaaat cagatatgtc tacttctatt ccaggcgttt atgcagctgg
     4321 tgacatctgt acctatgaag gaaaagtgaa actgattgct actgggctcg gtgaagcacc
     4381 tactgcagtg aacaacgctt tacactatat taatccaaag gaacgaactc agcctggtca
     4441 cagcacaagc ttatacgata aaaatcttcg tcctagttga ttttttatat ctctttgcat
     4501 ttcaagttaa acccgaaagc agtttcttgc atttttttca tgttccgtta acatgaaata
     4561 gagaaagaaa aaataaaggg ggagcaataa tatggtcgtc aaaactgaga ctttagaaga
     4621 aaaggcaaga gaactattga aggaacgtgg cgtaactgta gaagatatcg cacaacttgt
     4681 catgttttta caaaaagact atatttctga tttgactttg gcggattgta ctgaaagtgt
     4741 caacagcgtg ctaacaaagc gtgaagtaca taacgccatt atcactggaa tccaattaga
     4801 tatattagca gaaaagaaaa aattgatgag tccgttgcaa catattatcg aagatgacga
     4861 aggcctttac ggtatcgatg agatcctagc cttgtcaatc gtgaatgttt acggtacgat
     4921 cggctttacg aattatggtt atatcgacaa ggtgaaacct ggtattttaa aagaactaaa
     4981 cagccacgat ggcgttcatg tccatacctt cttagatgat atcgtcggag cgatcgccgc
     5041 tgctgctgcc agtcgattag cacacaaaga accagaaaaa agaagtcgcc ttactcaata
     5101 attcaacaaa aaaagaaaga aaacgtctat ttagacgagt tctttctttt ttgtttgttt
     5161 caagctattt tttcctaaga aaagaaaaac agcaaaaaat aattctaata atacaaaaaa
     5221 taagataaag ctatgcatga aaaattcttc tggaagtaca ttgatgattg gatcagtaac
     5281 gggatcgaat aaccagtcat cgttgttgaa aaacgtttca tgaaaaagga taaaaaagcg
     5341 atcaaatcct atcatcatga aaaaaccgaa aacaactggc agtaacatgc cgatttgaaa
     5401 cggacgaatc aaccgccaaa gccgatcatt cttttgcaaa tatttgataa acaaaatact
     5461 cgggatcaaa gtgatgaaaa acacagcata atccactaaa aacaaaattt tcacttcata
     5521 aaagtgatgg gctccgctag cagaaactgg gaaatctggc aagctgagga tggttttgaa
     5581 gggattattg agataattca ttaggtgatc aaaatttttc agtaacgtct cttgatctaa
     5641 agaagtataa tccaaaattt gcaaatgtcc gatatcaaat acgtatagtg gtcgaaagtt
     5701 gatcgtcaca ccaactgcca gactgatcag tgtcagaaat aggctgaaca atccagcata
     5761 ttccatccac tgccatctcg aatttttcat attagaagct ccattcatcc agtgattgtt
     5821 tcacataggt agctgggata ggcaacccag gtacatcttc ttcttttgta aaacctgata
     5881 aaacgagcaa agtatctata ttattgcgta tcccagcttg gatatctgtt tcatagttat
     5941 ctccaaccat gattacttct tctttttgca gccctaatac ttcaacggct ttatccataa
     6001 tgatggcttc tggttttccg atgtagatcg gcggcgtttg ggttgctgtc tctacaaaag
     6061 agatgactga ccctgctcca ggaagaaggc cgcgttcagt aggtatattc ttatctgggt
     6121 tcgttccaat gaaagtagca cctttttgaa tagcaagtgt tgctttaact actttttcat
     6181 aggtcagata attatctaag cctaccacta catagtcagg agcctcttct tcccatgtaa
     6241 atccggcagc taaaatcaag tcaatcaatc ctgcttctcc gataacatag acttttttcc
     6301 cttttccatc tgctttcata aaatcgattg ttgccaaagt agctgtgtag actgtctctg
     6361 gagctacatg aatgtcaaac tcatctgcta gacgattagc tactgtttct ggtgacttag
     6421 tcgtgttatt ggtaacaaac aagaaaggta attttctttt ttgcaattct tccacaaatc
     6481 gtttaccggc cggtatgggt tgtgtcccac gataaatcgt tccgtctaaa tcaattaaat
     6541 atcctttata gtccattcat ccactactct tccctttttc tgatcgtaaa tgctgttttt
     6601 gttttttcta cttgtttagg ttgttcttgt ttttttactt tttcagaggt ttttgctgac
     6661 tctgtttttc gatttttaat aaccggtttt ttgcgattag atgcgactgg tccttttttc
     6721 tcatcgatat acgcacgatt atggtttttt ttcttttttc ggcgctgagt tgtcttttct
     6781 tttttaccgc cgattctctc gatgacaaaa tacgcacaac caaaattgca atattcgtaa
     6841 agatagtctt ccaaggaatc gattcgctga tctggatgcg cccgtcgatt atccgcttgg
     6901 aaaaatcctt ttaggcgtag ttgttcataa ccccaatctc ctacgatata atcatatcgg
     6961 gctagtacat cactgtaacg ttctccaagc ttttctgcat taaatccttc acgataatcg
     7021 gacacaagcc gataatgtct ttcacctatc aaaaaattac tgtcatctaa cagtgtcact
     7081 agctcgcctt tgactttttc tgctttaggc tcctcaacga tttcttccaa agcagctgtc
     7141 agttcttcgg tgactgttgt ttcctgttca gctgatgatt ttttcttagc aatttctgtt
     7201 ttatgctcaa cgttctgctg ttcattttgt tttgcagaca tgcgttcacc acctatcttt
     7261 tttattatac cttgttttta tttgattggg tagtgagctt tcaagtaatc tcctaccaca
     7321 cttcggataa attcagggaa caaaaattca ttttttccag caatctcaat cgttggaaaa
     7381 aatggaacaa acatcaaatg atctacggta gtaaaagtat aatttttatt cagatcgatt
     7441 ggcttgttct tccaaaagac ttgatggtta atagaatcat atgtgattcc attatagacc
     7501 atctgcccaa aaatcttacc gcgaaatccc attcccttca taggatagtt acgtaaaaag
     7561 ttacgatttt tttctatttc taaaactaag cggatcagat catttccacc caatgtgaca
     7621 tttaacaagt gcatcggatg cggcaacgca gtgtgaagct gatcctgatt gacccgccct
     7681 tttggaattt cagttaaaaa cagaccactg tttaatattg ctgcttccgt ctttcctcgt
     7741 tctttcaccg cctcaaaggc tacttggata aacgaatgct cattgaagat atctagactc
     7801 agagaaaatg gcaaatctgc tacttctttt tcttttaata attcatgccc acgttctaga
     7861 taactattta tttcttgttc atcttctgta aaagctgtca ttgtttcggt agggatggct
     7921 ttggctgaat gcttaaggat ttttttctct tcatcgatgg ttaaatggac ttcaccgaca
     7981 tactgcccgt actttccagc ggctgctatt tggacatcat tgattacgtg accttctctg
     8041 aataaatgat gggtgtgcga tcctaaaata acatcaattg ctggtatttc ttttgcaatt
     8101 tggaaatcat cctgaatccc gagatgactc atcaaaacta aaacatccac ttgtgaacgt
     8161 aaatcttcga ctaattctgg caaaatatca taaggattcc gtatgtccca gccattcgga
     8221 ttataagtaa gcggaaatgg agcagtaaat gcaattagtc cgattttcgt ctggtgtttc
     8281 gttgtaatga ttttatatgg tttcgtccat gccggtggct ggagcgtatt tttatcgaat
     8341 aagttatcca ggatgatatc aaactcagca tgatcgtata aatgattcaa ctcttctttg
     8401 gaatttccta cgccttcatt gtttcctatc gtcgctgcat cataaccaac ttcattcatc
     8461 agcaagatat tttcctgtcc attcgttgct tctgacaatg gatgccaacg atccacaaaa
     8521 tcacctagat ctactgcaat cgttgtcgtt ttttctttct tttcgttttc tcgtttacgt
     8581 tgatccaaaa accttctgat ccttggccaa ttttctaaat gagaatgcag atcattcgta
     8641 tgtaaaatca ctattttttc catgtaccct ctcgcctctc tttatcttta tcataccata
     8701 ggcagctttt tcttccattg aaacaagctc tatttcagag tttttcctgc cttgaagcaa
     8761 attgtataag tacaatattc gataaatcag tctggctaaa aaatcaggaa cattcatttt
     8821 tacagtacta taaaaataaa aaaaacagac ccgaaagtct gttgtcgttt cattataatc
     8881 agacacatgg cggaacctgc ttagtgctgc ttccttccag acctgacacg cttcacaagc
     8941 ccaccattgt cctagccttt cggcaaagaa tagtatacct tatttttcat tcgttgacca
     9001 gtcttttttt aatttctttt ttcgctggcg gagctttcgg aaaaagtcag tcaaaatcat
     9061 cccacattcg tcttctaaaa tgccaccttc tacatatgct tggtggttaa accgctcgtc
     9121 ctccaaaaga ttcatcaagg taccggctgt tccgcctttt ggatcatacg cgccgaaata
     9181 aacttctgct acacgagaca aaatcatcgc gccgctgcac ataggacaag gctctaaggt
     9241 aacaaaaagt gcagcatctt ccaagcgcca gcttcccact ttttcacagg cttccttgat
     9301 tgcaagcatt tctgcatgtg tagtagcatc ttgcgtggtt tctctaaggt tatatcctct
     9361 tccaatcact tttccatcca atacaaccac tgctccaatc ggaacttcat gaagcatttc
     9421 tgctttcttt gcttctgcca atgcaaggcg catccatttt tctttttcta ctgcatcaag
     9481 atttgtattt accaattacc cttccctgcc tttgtttttt cttgttttac tttagcatat
     9541 gataaaaagg ctgtaactaa cttttttttc tatggtaaaa taaatacaag aggtgaacaa
     9601 gatgaaaatg gataaattac ttgctcttta cccacaagca cagaaaaaaa actctccagc
     9661 atcagaagcg gatatccttt cttttgcaat tgatgatgct tttatctgga tcaaacaaga
     9721 ttcattatct caacaagaaa ccagcctttt gaaagcgtta ttccctgtaa tcaacgatca
     9781 aaaaaaacac ccatggtatc actatctttt taaagatgct tcttgtgttc aagaaaaaag
     9841 ctttcgtttg atccagcttc acgtcgaatc aaaaggagaa ttcttaaaaa aagaatggca
     9901 agatactatt ttggaattat ttcgctattc tgctgatttc tttttttata cagacacaga
     9961 tgcgctctta gtcgaacaaa taaaccgtga ttatcttgat gctactgaaa tcaacggtat
    10021 ttttctatct ttagatgctg attttgatac gacaacgtct gtattcgttg gttctttcca
    10081 ttcacctggc accgacctcg tccctttgtt tgctgaagaa agaaaaattt ttttaacaga
    10141 gcaaaacaat ctttatactc acagccgtac tttttctatg caagatgtgg ctttacatta
    10201 ctatacaaaa gatactgtaa aagatagtaa gttgatcaaa agttacatag aactgatcaa
    10261 acaaaatgaa atggaagtga tcattcaaga attatggaat gaattaggca atgtcagctc
    10321 tgctgcaaaa acactgtttc ttcatcgtaa tactctaaaa tatcgaatcg aaaaatttca
    10381 agaacagtct ggtttcaatc taaaaaaagc caacgattta ctgttttgct atcttttatt
    10441 gcttcatgaa cataattaaa gatagattaa aggggttgtg acaataattt tgtcacaacc
    10501 ccttatttcg aatgaatagt gttcaaaagc tagtttctct tacatcattt tttcaacaaa
    10561 atgcattagc cggtctttta catcttcggt tgaatctttg attgaatcac cataaacaga
    10621 gattttcttt tttcctgatt tgatttttgc taacattccc atcaaagaat ccaagtcact
    10681 atctgaaaga ccatctacga tttctagtaa tttttcattt ccatcaaatt tgtcatagac
    10741 gaattttttt actttcgtcc gagtagtcat atgatggatc ttttccatta cttttcccga
    10801 tacaacgact gctgtcgcta cactggcagc ggctgctacg cttaatccga ttgttacttt
    10861 tgttgatgtt ttcataagta tcagctcctt tttatctatc tccatcatag catagacaaa
    10921 aaaataaacg aactaatcca ctcagtgaaa tctcaatcct ttagggaaaa agttctttac
    10981 tgttcctttt acttgtttcc caaatccgac aggtatctta tctaatacta gcaaaaccca
    11041 tccttgattc ccatcacgtt gaaatgtttc tcctgctgtg taagattgcc attccttttg
    11101 agtgatcggc aagcaaggta tattctctat cttttttgta gcaagcgcta atgcatagct
    11161 aggttcaaat cgattctttt tgaaatctcc taaatgcaaa cctgtacgta cgacttttaa
    11221 accatcgaga gaaggggcta actcaggaac ttcccaaaga tggtcgttga acactaaaag
    11281 tcttccagta gcttcataat gaaaatcatt tgaaaactcc gtccagagtt tttcctgctc
    11341 ttttgtcatt tgcactttac ttttttttcg tgtcttcttt tctttatgca tctgattttg
    11401 tccatgaaaa gtcagctttg caacaaaatg tccttcaccc tgatctttat gaggccatat
    11461 acgtattgtt ttttccaaac cagctacgct tccccattca gaacgtcctg aactaacgga
    11521 ttgagtcaaa ggaatctcct caatcgttac tggataattt tctacaagcc agctaatgat
    11581 ctcttcattt tcttctggtg caaacgtaca agtcgaataa atcagttgtc ctttattttt
    11641 tagcattttt attgctgaag acaaaatctc ttgctgacgt ttttgacagt atagcggaga
    11701 ttcttctgtc cactctttta ttgcatttgg atcttttcgg aacattcctt ctcctgaaca
    11761 aggagcatca accacgatcc gatcaaaaaa gcccgaaaaa tgagggacaa gttctgcggg
    11821 tgcatgattt gtcactattg cgttcgaaac tccccatcgt tctatatttt ctgataaaat
    11881 cttcgcacgt ttcggaaaga tctcattcgt cactaataac cctttcccct tcatttgagc
    11941 agctaattgg gttgatttac caccgggagc cgcacacaaa tccaaaactt tttcaccggg
    12001 ttttgctgca gcagctgttc caacgatcat tgcacttggt tcttggctat attcataccc
    12061 agcttgatgg aggaaagact ttccattgac agtgccaaga aatccctcat tgctgtaggg
    12121 agcgggttgt aattcttcgc tatggtaagt ttggaccatg tccaatcctg ccggttttag
    12181 tggattccac cgaaatcctt ttttcacgct tccttgttca agcgcagaaa aaaaatcgga
    12241 tgcttcttcg cctaaaagaa gacgatattt tttgataaat tgctgtggta acgttgtcgc
    12301 ttcctccttc attccaatgt ttcgttagac attttacaat cttttttacg aaaaataaag
    12361 gtggctgatc tactttttca tgttgctgcc taaggtgact gttcctttaa gatattttcc
    12421 aagtattcat ccgtcacctc gtttttatcc caaacagcgt tcatcatttc aagaaaatct
    12481 tgagaagaat catctgagcg caaacttccc aatgcattaa gccataccaa ttcaagcgac
    12541 ttttcttctt tgatcttcgt gtgacctttg acatatgaga aaaatggccg cttaaatagc
    12601 gaatccatgt ctaaatcaga ttttgcaatg atttcacgaa tactttcatg gatagaaaaa
    12661 aaatctttca ataagtagac aatgcttaaa acatcatcgg aactgcattc agctaagtag
    12721 ttttcaaaat aaacagtgat ttcttctaat atcttctctt ttaacccgct gattgatttg
    12781 aaatgtgtat aaatcgggta tgtagaacaa ccgcagaact ctgctaactc tcttgcagta
    12841 attgacttca ttccatattc ttccacgtat accatacttt tgaacagcaa atattcttta
    12901 ctataatttg ttactctccc catcattctt acctccgtct cttttcatct acccataaat
    12961 aaataacata aataattcta aaaatattat tgataattat caaaacatat ttagttatat
    13021 ccattaaaaa tcaatttttc cgccttaaaa acaagaatat cttgacaaaa taccctagga
    13081 aataaacaat agaataaaca aggtaacaaa aaaattaaat aacgttatat aaaaaagaag
    13141 gcgacactct gtgagaataa cacagactga aatgactttc cactcacagt ttttgtctaa
    13201 ctatatacaa aaacagaata aaaaggaggt atttatgcta attgaagcaa gaaaaaaaga
    13261 gttacttgtt ctacaaatgg tcattcaaaa aaataattgt tctttacaag aattatccaa
    13321 tgacttacat attccaaaac ggacaatcaa agaactgatc cgaaaaataa atgtatcact
    13381 caagcaattt ttattgattg atgaatttat ttattctaat cataaaggag agatccaaac
    13441 caaagaaacc gatcaaacta aaaagttagc tgttttttct aagttaaaat tatgctacct
    13501 aaaagaatcc aatcgtttta actatttgat gttactaatc aattatccac aaactgctgt
    13561 accaaaaaaa tatttacttg aacaacttta tatatcgccc tcctatctcg aaaaactgac
    13621 aaaacagctc aatcattcct taataaaatt ccatttacgg atcctatctg taaaaaattg
    13681 ctgtactctt gaaggaaatg agttatctat ccgtctctat ctttactttt ttctttcaga
    13741 tacatttgga ggtaacgatt ggccattttc ctcacttgaa ttaaatgcac taaaaatgaa
    13801 cagtacagat gagcaaatag aaaaaatttc aaaacaagaa aaaaatatct acttgctgtt
    13861 aactttattc atattacgaa acaaacaaca ggcatatttt ccaaaaactt cttctgaaat
    13921 cactgaattg atggacttat tgcagcatac acatgattat tcagaatact ttacttcttt
    13981 ttcagtgagt cgcccttgtg aagagacaga aacagagaga gcctacttta attatttttt
    14041 ctattgtttt tttccaaatc aaatctcttt tcgacaaaaa caggagattg gttttttatt
    14101 ttccacaagc aaaaacctta tttgtcgaca agtcggtcaa ttgatgactt acttaactca
    14161 acagtttcct ctcaaccatt tagaaaataa aataccaatt tatttttatt ttcttgtgtt
    14221 ggcagttgtt tttttcgaac tgttgggtga atccagcagt agtttttcta cactttgctt
    14281 tccagaagcc acgtccaatc attctagttc ttttatacag gaaaagaaat taagagaaaa
    14341 aatcgataca attttttcaa aaaatgggga aagaaaccaa atcagtcaat accttagtca
    14401 attgatccaa cacttactac aaacagaaac gaaagagcag ttactcatcc atttgcagat
    14461 aaccaaacag tttacaggaa attatcatct tcaaagccat ttgcagcagt tatttcgcaa
    14521 agatgctgtt aaaattaccg catattcaga acatgctgat ttgatcatta cagatcagca
    14581 tgagaaaatt tcagatgaaa cggagacttt ctatctggat acaacgcaca atacagtgtt
    14641 atttggcaag ttaataaaag cggttcatga actgtatatg aaaaaaggtt atgagaacaa
    14701 aacaaagagg atgtgacaaa attcttgtca catcctctta ttccaaataa atggtattca
    14761 atcagctaac tctcggtatt agctcagatc aaagcgctga tttcacaact tctttatttt
    14821 aatctcttcg gttgccgccg aacaataaga tcaagcgcaa cagctgcagg aatgtcgaaa
    14881 gcgctgctgc aacataagtc agtgctgctg caaataatac gtgtcttgcc atcggtactt
    14941 cttcttccgt cagtagtccg ccttcactca aaatttggat tgctcgccga gacgcgttaa
    15001 attcgactgg taatgtcacc aattggaaaa gtaatgctaa agaaaaagcg aaaatcccga
    15061 tattgattaa cgtagagttc cagctaagca atacacctac cataatcaag gggaacgaaa
    15121 tcatcgaacc aaagttagct gctggaacaa gtgctgcacg aatcttcaat gggacataac
    15181 ccgaagcatc ttgtaccgca tgtccgcatt catgagctgc tacacctatc gcagcaactg
    15241 aagtagactg tgcagttgct tgagacaaac tcaacatctt attacctgaa ttgtagttat
    15301 ctgtgagatc tccggcaatt tgttgaacac cgacattatt tatctgttga ctttgtaata
    15361 tatattgtgc tgcttgtgta ccagtcacat tgtttttgct tctcacttga tcgtattttc
    15421 ggaaagtact attgacgtac gctgacgcaa ttccggaaat aactaatcca agaatgacca
    15481 aaagaaatgt cggatctaaa aaaccataca ttccataacc atacattttc gtttcactcc
    15541 ttttcgttta ctttatttta tcattagtag taggaaaaga atgtgaaaag accttgaata
    15601 ttctttaatt ctttttcaca aattccgatt tcagtttcat cggtccaaat ccttctacct
    15661 tgcaatcgat attatgatcg ccttctacta aacggatgtt cttgactttt gttccttgtt
    15721 taatggcacc tgacgcacct tttactttca agtctttaat cactgtcacg ctatcgccct
    15781 ctaacagacg gtttccattt gcatctaata ccactaatcc gtcttctatg acagtttctt
    15841 gttcttcttt gttccattcg ttcccgcatt ctgggcaaat caacaagcct cgatcttcat
    15901 atgtgtactc tgagccacat tctgggcaat ttggtaatgt catcttcttt ctcctttaaa
    15961 atctttagtg agcactattg taacggaaaa agaagatctt gaaaagatac atttgtgatt
    16021 tttactacaa aaggcacgtt ttcgaacgaa gtatcattct gtttttctgc tcttatacga
    16081 ttggcatata tcttggatct ctttatagat ttcctctact tctgctaaat cttttgcatt
    16141 cgcaccactt gctaatggat ggcctcctcc atgatggcgt ttagccaatt cattgatgat
    16201 cggcccctta gaacgtaaac gtacgcggta ataccctgaa ggctgctgaa caaaaatccc
    16261 ccaagccagc acttcgtcaa tcactccagg aagtgaaacg atcgaagctg tctctgaatc
    16321 atcgattcca tatttatcaa gaatttcttg cggaaggatt attcttcctg caccattttc
    16381 atccacctgg atattttgat aaagataacc ggaaagttta gcgactttca tcggcatttg
    16441 ttcaatctct ctgttcaaag cacttgcatc aaatggataa tttctcaata tcgaagcaat
    16501 ctctaatgta cgggacgtcg tggagggata caaaaagcgc cctgtatctc cgacgattcc
    16561 tgcataaagt aaccgtgcag ccttaacgtt catctttaaa gattcaggaa acatcaaagc
    16621 aaattctgca atcatctcac tacagctact tgcttttgta tttacccaca caagatctcc
    16681 ataagggtca tcattgggat gatggtcgat tttgatcagt ttttctgcca actgatatct
    16741 ttgatcactg attctgggtg aattagctgt atcagtcacg atgactagcg ctccttggta
    16801 gaagacatct tcaacttctt gcatttctgc taaaaagcga agcccttcaa tcgtttcacc
    16861 tacttgacgt atttcttttt ctgggaaact ttcccgtaat agttcggcta atcctacttg
    16921 tgatcctaat gcatcaggat cagggcgcaa atgcctgtgg ataatgattt tatcgtattt
    16981 ttttattgta tctactattt cttgctgtac tgtcatttca ctcctgcttt ctaagaacgt
    17041 tccattactt gacaaacaac gattgctttg gaaacgatgg tgttttcaat aaacacttcg
    17101 atatccagtt tagcggaacg tctgccgatt tccaatacac gtggacgaat gtctaattcg
    17161 ctttccaatt ggatcagccg caaataatgt aggttcactt gttcaatcaa gatatttcgt
    17221 ttttggttca tcaccattgt tttttgtgcg acatcagaaa tgatttcgct aagtacgcca
    17281 aaagaaatgg ttccaacgcc attgaccatt tgtggtgcta ctacgaattt gaacttaggg
    17341 ttttccaaac gatttccttc acggtcagta tcaatcgtat ggatatttcc agatatctga
    17401 tccgaaatcg tatctgcaat ctgcggttgt cgctggacaa gctgcatcgc tttcattaca
    17461 tcttgccggg taatcaagcc ttccaatgtc aagtcatcgg aaacgaccgg catgacttct
    17521 agcccatccc agatcatttg atggctaaca gaggcaatac tcattgtttt ctttacactg
    17581 attggttctt tcgtcatcac ccgatcgatg atctggtttg gcgatttccc taaaacatct
    17641 tttgccgtaa caatccccat caaacgatga tggcggttga cgactggaaa acgcgaatgc
    17701 tgcgtttctt ctgacaaacg ctgataatca gaaatcgtat ctgtctgctg caaataatga
    17761 gtcttttcag ctggcatata gatatcactg acaagcatga tatctttttt gatcaattgg
    17821 tcgcttaacg ctcggttgat catggttgcg actgtaaatg tatcataaga ggtgcgtaag
    17881 atcggcattt caagatcatc agctagcttt gcaatctcag cagtcgtatt gaatcctcct
    17941 gtgatcaata ctgcggcgcc atcttccaat gctaattttt ggacttccgc ccggttgccg
    18001 acgatcatta gtgatcctgg cgtaatatag cgttccatgg catgtttagt catcgcgccg
    18061 atgacgaatt tattcaagac cttgtctaat cctgccgccc cgcctaaaac gtccccttca
    18121 atgatcctga cgacctcgcc aaatgtcaaa cgttcaatat gtttttttaa tttgcgttcg
    18181 atacggatgg tccctactcg ttgaattgtt gaaactagtc cgacattttc tgcatctttg
    18241 attgcacggt acgctgttcc ttcactgaca ttcaattctt ttgcgatgct tcttacagaa
    18301 attcgattgc caacaggtaa actttcaata tattctaaaa tcaaatcatg ttttgtcgcc
    18361 attttctgcc tacacttcca gcgtttccga gacgctcatt atttttcctt cactatcttc
    18421 cagtaactct acaaaagatt cgggatcttg ttcaatgaca gggaaagtat tgtaatggat
    18481 tggaactact ttcttggcac gaattgtttg cgcagccttt gctgcatctt ctggccccat
    18541 cgtatagtta tcgccaatcg gcaagaaagc gacatcaata tcgaattctt ctgcaagcaa
    18601 tcctagatca ctgaaataag cagtatcccc tgcatgataa atcgtttttc cttctgcttg
    18661 aataataatt ccgctaggct cgcccatata ctgaacgata ccgtctactt catagcttga
    18721 actatgctgt gcatgtacga attttaccac gccgaatgga aacgcatgtt ttccaccgat
    18781 attcataccg aatgaatcta ctcctctgct gttcgcataa tcagcaatct caacaatact
    18841 gataattgtg gcttgatttt cttttgcaat aggaatcata tctcctatgt ggtcactatg
    18901 accatgagta atcagcaacc aatctgtctt tacttcttct gcagttaagt ctgtcaatgg
    18961 atttcctgta ataaacgggt caatcatcac gcgttggcca ttttccattt caattgttaa
    19021 acaggaatgt ccatgatacg taattttcat attttacacc tcgcgttttc tctgtatctt
    19081 ttttattaaa aacgatttca tcacttgcac atcaatgaaa aaatatagct gctaaatata
    19141 ttttcattgg attgatagta cagtatgtac aaagcaattg taacagataa tacaggatgc
    19201 accaagtacc aagcagatat aatctcaagt ttgaggtctc tgctctgctt agcttctctt
    19261 ctcgtccctt aactaattaa atcagcgtaa ataggatgga cgatcttttc taaatcggct
    19321 acttttatcc gaaggcttct cccgatttca ccgcttgaca caattacttc ttctttttct
    19381 tttaaagaac tgtctgctaa aaaacaataa tcaggatgtg cgagttttat tccaataggg
    19441 gtgtttgctc cgtggggata tcctgtatgc attaatacaa aatccattcc aggaaaacca
    19501 actttacgat ctttcgtcac ttgtctcgtt tttttgtaat ctaagtgatc gttcaaagga
    19561 atcaatgcga tgatcacccc agttttgttt cctttcacta cgagagtttt acatatcaaa
    19621 gctggatcaa tccctctttt ttgtagttct tctgtgaaag attcttctac cacatgacta
    19681 aaatcaagtg gttgatagct gatcttttgt tcttctaaat aacgttcgac ttttgtttga
    19741 ctcatcattg attcactccc tttattctat cgtttattat aaagcgaggg atgctgtatt
    19801 caaaaattat ttgtttttcg caaaaaaaga gcaagacgag cactctatag agaggttcat
    19861 cttactcttt ttgtttattt tttatttcga cgttgagtag cttccataat gactggcaag
    19921 atcactgggc ggcgttttgt ttgttcaaat aagtaacggc ctaattgatc tcggatgtct
    19981 tgctttaatt tgctccactc aaaatcattg ctttctaaat gtttctcaac gattgtttca
    20041 atcatattgc tgctttcttt catcagatca cggctagctt ttacgtaaac gaatccccgt
    20101 gaagtaattt gaggttttga aatgattttc ttttctcgcc gactgatagt gacaaccgct
    20161 acgaaaatcc cgtcttctga caagattttt cgatcacgta aaacaatgtt tccgatatca
    20221 cctatgccta atccatcaat cattacattt tctgcacttg tagttcctgc aacactcata
    20281 cgcttgttct tatattccag cacgtctccg cgtccagtaa tatagatatt tttgtatggc
    20341 atccctactg catgagccaa atctgcatga gcagctaatt cacgatactc tccttgaact
    20401 ggcacaaaat atgttggttt catcaaattg atcattaatt gcaagtcatt aggattggca
    20461 tggccagaaa cgcgcatatt ctcagagatc aacttcactg ttccaccagc tcgataaatg
    20521 atatcttccg ttttcgccac gatggtttcc atcgcgatgc ttggcgtagt agtgatataa
    20581 accaaatctc cttcttcaat cttgacatta cggtgtgtac cgtttgccat tttttgcaga
    20641 gacttgatgg gttcacccat tcggccagtt tctaaaatga tcagttcttc tggatcatag
    20701 tttttcatgt ctttcaacgt aacaagcaga tcttcacttg gtaattgaag tttttctaaa
    20761 cgcatcgctg tgcgaataat tcgttcgaaa tcttgaccag tcaagacaac ttttcgttgt
    20821 gctttttctg ctgcatccaa tacttgttgc actcgttgca aattacttgc tacacaagcg
    20881 acgatgatac gcccttccca atatttgatc gtatcaaata cttcatctgc tatttgggct
    20941 tcagaagcta caggctgagg attttctgca tttgccgatt cacttagtaa ggctaagact
    21001 ccttctttgc cgatttccgc caatcgtgca taatctgttt gatacattgg gatagccgtt
    21061 tggtcaaatt taaaatctcc cgtataaacg atactacctt cttttgtttt cagattgatc
    21121 cccactgaat ctggtatcgt atgagtggta cggaaaaagc tcactactgt ttcaccaaag
    21181 tctatttctg tatgctcatc taccacatgg aaatccttaa atcctttggc tgcttcatta
    21241 cgactgacat tcaattttgc taactcgatc gtcaactctg tcccgaatac tggtacagaa
    21301 atttttgaca acaagtaagg aagtgccccg atcgcatctg catgtccatg tgttaaaaag
    21361 acaccagcta cacgatcaat gttttcttct aaatacgtaa aatcagggat tacgacgtcg
    21421 atccccaaca actcattttc aggatatttt agcccacaat ctaaaataaa aatatcctcg
    21481 cccacttctg cgacatacat gttttttcca ttttcacgaa cgccgcctaa tgggataatt
    21541 ttaatggtac tcacaaactt cacctcttct tatgacatcc aagtttaaag atgtcgattt
    21601 tcttctttat ctaaatatat gagccattcc aatgaagcat atgcaaaatc actatttctc
    21661 aacttatgga gaatcagcag gaaaattacc agcacatccg cgttctgaca gttggatggg
    21721 cattttattt tggatatact tcattaacaa aatggatctt ttgcgaaacg ctatagccag
    21781 aatacttata taagtattca gctgttcccc attattatac aacaaataaa ctaaatcgct
    21841 agtatcagca attgttagaa caactatgca cgtaaaaatc cctctgtagc atctaggatt
    21901 tcttttgcta ttcctctttc atttcttctt cgtcggtttg aaacatactt ttttcatttt
    21961 accacatttt ttgcaataac tatagtgact ttttatatat acagaacctc atgttgatgg
    22021 tgtgcaaaca gcataagatt taagctagct ttaagatagg ttgtctatta tcaaatgcat
    22081 ctactaggag ggatgcaaaa tatgaatttt atgaaacgtg catggaaaag tacaaaagta
    22141 aaatggggac gttcattgtt attgtttgcc gtgttcacag ccattcttat ttttgtgcta
    22201 gctggcctca cgattcgaag cgctgcagaa gaagcagcga atcaagcaca aaaagaagtt
    22261 ggagcaacag tgactttaag tgccaatcga gaagcttcat ttaaaaaaca ggaacaaact
    22321 tcttcaagcg gttctaccac tgaagaacgt ccagatccag gcagtttttc tcttacacca
    22381 gtttccttaa cggacgcgga aaaaatagct gaattagata atgtaaagag ttattccttt
    22441 gaaagttccg cctcagctat ggcaaaagat ggaataactg ccatcactag ttctgattca
    22501 agtgaagaca gttcagaaac tactgatgca ggcggtgaac ctgctggagg aatgggcggg
    22561 aatccgcaaa tgactcaagc agactttcaa atcagtggtg tgtcagcaac tgcacaaaat
    22621 agtaattttt ctgatggaac agcaaaaatc acggatggtg aaggaataga tgacagcgac
    22681 aaaggcacaa acaatgtagt cattgattct actctagcag aaacaaatga cctggcagtc
    22741 ggagatactt tcacaatcac gagtactgaa gatgaagata ccacttatga aatgacgatc
    22801 aaaggaattt atgaatccag cgaaacaagc ggcagtatgg gtatgaaatt caacttcatg
    22861 aatccgtcga atacacttta cacttcttac acttttgcaa atgaactaaa tgggacatct
    22921 gacgataaca cgatagattc tgctatttac actctatctg atccagataa aatggatgag
    22981 tttctcaaag aagctgagaa gctgatcgac acagatacat ttagcttaca atcaaatgat
    23041 tccatgtatc agtcaatgtt ggaaccttta aacaacgtgg caagtttttc taaaaatgtt
    23101 gttttactag tggctgtagc cggtattatc atacttactc tgatcattat gattaccatt
    23161 cgggagcgtc ggcatgagtt aggcgtcttg ctatctttag gagaatccag aagtaaaatc
    23221 attctccaat tgtttaccga agtggctatt tgtatgattc ttgcattagg agttgcttcg
    23281 cttagcggaa acgtcgtcgc gaatgccgtg ggacagcagc tacttgacca acagacagaa
    23341 accacgacac aaaaccagca agctcctggc ggtggacaaa tgccaggtaa cagacaagaa
    23401 caaggcggtc aacgcgatgg tcaacaagga accacgaata atccatttgc tgtttctgat
    23461 caagtcagcg aattggaaat caatgtcaaa cctgcacaat tgggactatt agccggagta
    23521 gcatttggaa tcagtctgtt ttctgtcttt ttagcttcta tagggatatt aagattaaac
    23581 ccaagaaaaa tcctattaaa ctaaaggagg aatttgatgt tacggacaga acaattggga
    23641 ttttggtatc aagatccgca agatgcgctt tataaagatg tagaactgaa tttcgaagct
    23701 ggaaaaatgt acgctatttt aggagcaagt ggttctggaa aaacgacttt tctttcgctt
    23761 atttctggac tagatgcacc aaaagaagga aaggtatact atcaagatcg ttcactgaac
    23821 aaaatcgggt taagaagtta tcgtaaaaat gatgtctcga ttattttcca agcttacaac
    23881 ttgcttcctt atttatcggc tctagacaac gtcatagcag caatggaaat cactaagacc
    23941 aagcaagaga attatcgaca agttgcttta gatcgactgg ctcgtgtagg aattgatgaa
    24001 atattagcaa aaaaacaggt gaccaaactt tcgggaggtc agcagcagcg agtcgctatc
    24061 gttcgtgcta tctgctgtga acatcaacta atcgtagcgg atgagcctac tggaaatcta
    24121 gatgaaacaa cttcacaaga tatcgtcaaa cttttccaag aaatcgccca tgaacaaaat
    24181 cgctgtatta tcatcgtgac tcatgagatt gaagtagcaa aaagctgtga tgaagtcttt
    24241 gaactaaaaa ataaaaaatt tcaaaaaatc gaagtttaaa aaacaggata atgatcaaat
    24301 aaaaaatccg aaccatatct gtctcgcaga tatggttcgg attttttatt tgcttgattc
    24361 aattagtaat aagtggtttt tatttttttt cgtcttttcg agaaaacttg tctttgactt
    24421 cgtcgcctaa atttcgagct ttttctttga tgtcagcacc tagtgattgt gctttccctt
    24481 ctgtttcttt gctcttgtcg tctgttgctt tgccgtatgc ttcttttcct tcaccgacta
    24541 ctttatcttt catatcttta gaacgtcctt ttaaatctgc cattgtgctt cctcctctta
    24601 gtttgtttat tgatctacct tcagggtaac atcaacaaca gatacagaca aacagaacgc
    24661 tcgttttcta aaaaagatag ttagagctgt tgattaaaaa cttttttcga aagtccccca
    24721 tactttgact tctttttctt ggaccattat ttctccttta gcgataactg tatcaatatc
    24781 aagcgtttct ttatccaaga tacacagatc tgcatcagca ccaatttcga tttttccttt
    24841 tttatccaat ttcaatatac gtgctggatt actggttata gctcgtaagg cgatttccaa
    24901 agggatactt tctttttgca cagcttcttt gatccctact agcaatgcct tggcacttcc
    24961 tactcctaac cctaggaaat gattgttttc atcaaaataa ggcaagcttc cttgtccatc
    25021 tgaggtcatc gtgaaattat ctaaagaaac atcttcctcg atcaatcgtt tcagtgcttt
    25081 gctgaagcga acttcaccat ctgtcttctc ccaaaaatca ggatcttcgc tagcagtgaa
    25141 gtcaatcgtg ccaccacgtt tggcaaatgc cacgcaagct tcaaataatt ctggtgtgcg
    25201 atttgcatga gtaggcaaaa attgtgtgat cggaatttct gtttcttcta cgattcgtgt
    25261 caatagctct agctttcttt ttcctccgcc taagtggaca ttgatgatcc cagcttttcc
    25321 ggataacatg cctcctacac gagcatctgc tactgcacga gcgaactctt caaaacttgg
    25381 ctgagaagaa cggtgatcgg atactgcgat ttctccgatt ccgataattt tatcaattgt
    25441 caaaaagtct ttgatgatag aatctgttac tgtttttacc ggcaatcggt acgaaccttc
    25501 gtatacataa gtggagattc cttctgcttc cagacctttc gctttgctga tcaacgcagt
    25561 catatctcta ccttctccgt ctgttcccaa acaaccgaca actgtcgtta caccagctgt
    25621 agtcaattgg ctcaatgtga cttctggcgt tcgattttga taaccgcctt ctcctcctcc
    25681 acctaaaata tggaaatgac agtcaatgaa acccggggtt agtacttttc cctcacctga
    25741 aagttcttct acttccactc cttcgtagcc gccttctagc tgttcttcta cagccaaaat
    25801 cttcccaccg gcaatcagta catccatttt tcctaagtaa tctggtgcaa acacttcaat
    25861 ttgtcgaatg attttcatac atttttcctc tttctttaag tataactgat gataggatct
    25921 taaaaaataa tccaaacgat aggatcttta ctcctttgat tttaccgtaa aatgacggtt
    25981 cttggagtcc ttatctactg tttggattac ttttttattt acaggtctcc agtactactg
    26041 cagacctatt gcaatggcaa tcatgatgaa aatagttcct aaaacaaaca ggaatccttg
    26101 catcttgatt tggaatcttg cccattttgc ccattcgatc cgtgcaacac ctagcacacc
    26161 aatcaagctg gctgatacgg gtgtaaaagc gtccataaaa cctgaaccaa gctgataagc
    26221 aagaactgct acttgtctgg atacacctac taaatctgcc agtggagcca tgattggcat
    26281 agtcaaagct gcttgtcctg aatttgatgt aacaaccaag ttgaacaaac tttggaagat
    26341 gtacatcgcc caagcaccaa tgacagctgg aacaccggtc aacgccgtcc cgatcccatg
    26401 caaaatcgta ttcaaagctg aaggaacaga tgcatcagat cctcccaaga caagaagaat
    26461 ccctttggcc atacctacta cgattgctgt accagctaaa tcagctgcac cagattggaa
    26521 agaagaagcg atgtcattga ctttcattcc atctaatttg aaaagaacag caatgattcc
    26581 agcaactaat cccatcacaa agaattgaga agcgatttct ggaatgtaat agcctttttg
    26641 agtcacgccc caaacgatcc agacaaggac aactaacatc tctaataaga tcaatttatg
    26701 cccaagcatg aattttttat tttcatcaga tgtctttttg atatgagaac ggaaataatc
    26761 atctgatttg taagtcaacg aactttctgg ttttttacgg attttttctg catatatcat
    26821 catataacca gcggctaatg cagtaacaac tacccacata atcaatcgga atgtcgcacc
    26881 agacaacacg gggattccag caatcccttg agccaccgct acgctaaacg ggctcatcca
    26941 agaggtcgca tttccgactt gagatgcgac ataagtcacg gttactgcta cgatcgagtc
    27001 atatcctaac gcaatgacaa atggaaccat caccattgag aatggaatta cctcttctgc
    27061 catcccgaat gtagcgccac cgaatgaaaa agcaaagaat aatagcggta aagctaaacg
    27121 ctccagtccc ttagttttac tgataaacgc atagatacct gcgtcgatcg ctccggtacg
    27181 cataataata ccaaaagcac ctccaacaac aaggatcaat gcagcgatcc ctacagcaga
    27241 tccatactta tctccagata ctagtccttc aaaaacaaaa tttaagaaac caaagccgcc
    27301 aaaatcatct gttccccata ttttggctgt tttatgcaat tttttagaag tatcatagat
    27361 attttcgccg tactgatcgt aaagcacatc atctgtcaag gagatttcat ctagtttttc
    27421 ctgcgtaaga tttttttctc cgtcagcaat gactttttcc aatccttttt ccggaacatc
    27481 cagtttttca cgttctgctg gatgatcttg cagttcttct aattgatcaa acacatacga
    27541 cttatccagc tcgtaagcat aacggaagga atcttgacgt aaaacagtac gagtacttgt
    27601 ttcgccattt gcatctttgt attcaatatc ttgcgtgctg aactttcctg ctggaacgac
    27661 aaaagtcagt atccatgcaa agatgactac accaaaaata atgacatacg tatggggtgt
    27721 cgataattta gtgaagtcgc gtttcggttt tcctgaagaa tttgttttct tcaaatttat
    27781 ttcttccttt cttttttcag taattttgat gaataaaaaa tggataatca aatgaattat
    27841 acagtaaaaa tgacatttcc acatgaataa tttattagaa aatcactttt ttctattttg
    27901 ttttttttct cctatgtatg attatttttt tctctttcca tttatattaa gtattttatt
    27961 tctctgtttt tccttaaaat tcttttttta tttttagatt agagaaaatc tcgtcctgtt
    28021 tttttcattt tacaatcatt gaaaaattga atttcattgc aaaaaaaata ataaacactt
    28081 ataaatatcc attatctatc cttcaatttt tgtgtatttt atttctatta gaaaaaggta
    28141 tcctgttgga caattttgtt atatcaggta aacttcattg caataatgat aacaaatgta
    28201 ctataattac tttgtaaaga gttttgggga agactctttc atcaacgtgt attaagagac
    28261 aagaaagaat ccatatggat tctttcttgt ctctttttcc actacttttt atttttctga
    28321 cactacatat tcttataact catttctcat aactgtgaaa caacttataa aaataacaaa
    28381 ctttaaacaa aacaagctta aaatcaaaga tgatccatct taaaataact aaaacaaaaa
    28441 aagtagtcgt tgttaatcct cattaataat cgttttcttt ttttcaaacg ctccattttt
    28501 atgtggaaca ttattttttt aaggaacttt gtcaacatgt ggataactat tttccacttg
    28561 tgtcctggac tagctgtttt gctgtaaaat acaaaacttg ctgcagcaaa aagatcgttg
    28621 caagagaggc tgttccgcag atcgctggat ctagatttgg caaagtcaag actgcatcat
    28681 gtaaattggc gtggttgtcc aaaaccaaat cagcaaattc aaataatcgc aaaccactgc
    28741 tatgttgcga tttgatactt cgtgacaaat caaatccagt aacaatgatt aatggatgac
    28801 cattttcttt gatccactga gctagttcga tgattgccgg gtttcttcct tcattcgaaa
    28861 gaagaagaaa aatgtcttct gatttgacag aaagctgatc aataattgcc tgtcctgcac
    28921 cttctagcgt ttcatagaca cctccggctg gattttcaat caatatactt ggtacaagat
    28981 ccggggtttg atcccaaaat tcaaatgcta caccacttag tgtgcggcta gcatatatct
    29041 gcaatctacc accttgatta atttgtttcg cgatccaagt gccagcttga agcatcagcg
    29101 gctcttctat ccttaatttc tcttccaatt ggtgataata gtcaaaataa cataaactca
    29161 tttatctctc ccgcctagct atacttgaca tgaatagaaa cagctgccta atctaaggaa
    29221 gtacataaaa aaacagtagt tagacagtaa cacatgtggt ctttgctgtt tcaaacacaa
    29281 aaaaggcatt gaacgaatac gcccaatacc ttgacatagc aaataaaaca acgtgcagac
    29341 catggaaaat atctacatag gggtagaatt ttcaccctag attaggtaca ataaattagg
    29401 tcgatgcact gcattgacta tggcaaaatg atcggtcagg gtgtatgtgt gtgactggtc
    29461 attccctgat tcttagcgcc aactaagggt cagggagcct ttttttattc agctgtttct
    29521 atctgaattt attgtaagta atctcttatc caagtgcaag caagaaaata caaaaaaaca
    29581 ttggtatgat ttatatatat ataaataaca taaaaaaagg aatggcttat cccgatacaa
    29641 caagcattcc tttaaaaaag attcttttat ataagtgaaa aaagcttttt tccaccaatt
    29701 aaataaatct ctcatctcaa tagtttatcc attattttat ctttttttgc gtatacctac
    29761 taaatattac cgtcttcttc tcgttcttct actttgttcg agagaatctg tactagaaaa
    29821 agtagttgta tgtctacctt ttctgcctat ccgagacttt cttttcatat atgggatata
    29881 aatgattaga tacagtacag caaaaaataa agcaaatacg caagcttccc aactacctaa
    29941 cgccaattca accatcaagg tagcaacccc aacggatgct gcataccaga taaaaatcag
    30001 aaacgtttct ttttttctga ccatgcgaaa catgataaat agactaataa gcaatagtgg
    30061 caacacaaat atccaattgc ttccttccat cagccacttg agtatatcaa gcagcgactg
    30121 tgcaacagcg actaattttc ccatagtgaa cacacacctt tttttataat taaaaaattc
    30181 gcctttttat tctactatga atcttctggc ttggctttca tttctcttat gtaatcattt
    30241 tcttttatac aacttaaaaa aaaattaaac cattagcata atattttctg aatctattca
    30301 cgaaagtctt tttctatctt tcgttttcca cgactcaact gatctagagt caaaaaacta
    30361 aaacgacagt tgcgcaaatg acgcacaagc tgccgcttta ataacaaata gcctttcatt
    30421 ctcagcaggc cacttatttc cagttaactt tctgttctta gctttttact caactggata
    30481 atatatgcac ttaatgaagt cccaatttcc gaatgttgaa gtccatattc aatatttgtc
    30541 ttcatatatc ctaacttatc gcctacgtcg tatctttttc ctttaaactc tctcgcatag
    30601 accgcctctg tctggttaag agtctgaagt gcatccgtta gctgtatctc gtttcctgct
    30661 cctggttctt gagtttctaa tatctcaaat attttaggag tcagtagata acgtccgata
    30721 atggctaaat tacttggtgc ttttcccatt tcaggttttt ctacaaaccc ttttactctg
    30781 caacgaccct tttcgctatc tgttttagga tcaataattc cgtatttaga tgtttcattt
    30841 tctggtacac gcatgacggc aacagcggaa gcttgtgttt cttcataatc catcatcaat
    30901 tgttgagtca atgggatatc atctttcatc aaatcatccc ccagcatgac gacaaacggt
    30961 tcatttccta taaatgcttt tgcttgaagc acggcatccc ccagtcctct tggatgagat
    31021 tgacggatga agtgaagatt gacttgagtc gtttcttcaa ctaaagcgag taattctgtt
    31081 ttttcctttt cccgcaaatt gttttccaat tcgatatttg catcaaagtg atcttcaatg
    31141 ggtctttttt cttttcccgt tacgatcaag atgtcttcga ttcccgaatc caatgcttct
    31201 tccacaataa actggatcgt tggtttatcc acgattggaa gcatttcttt tgccatggct
    31261 tttgttgccg gcaaaaaacg tgttcctagc ccagcggcag gaatgactgc ttttttgacc
    31321 ttcacttgct
//
LOCUS       DADGKS010000026        30739 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.026, whole genome shotgun sequence.
ACCESSION   DADGKS010000026 DADGKS010000000
VERSION     DADGKS010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30739
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.026"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            544..1872
                     /locus_tag="JXV47_001336"
     CDS             544..1872
                     /locus_tag="JXV47_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAX1487389.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            2074..2907
                     /locus_tag="JXV47_001337"
     CDS             2074..2907
                     /locus_tag="JXV47_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HAX1487390.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            2923..3660
                     /locus_tag="JXV47_001338"
     CDS             2923..3660
                     /locus_tag="JXV47_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HAX1487391.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(3815..4783)
                     /locus_tag="JXV47_001339"
     CDS             complement(3815..4783)
                     /locus_tag="JXV47_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HAX1487392.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            5015..5848
                     /locus_tag="JXV47_001340"
     CDS             5015..5848
                     /locus_tag="JXV47_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HAX1487393.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            5882..6721
                     /locus_tag="JXV47_001341"
     CDS             5882..6721
                     /locus_tag="JXV47_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAX1487394.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            6747..7307
                     /locus_tag="JXV47_001342"
     CDS             6747..7307
                     /locus_tag="JXV47_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAX1487395.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            7506..9227
                     /locus_tag="JXV47_001343"
     CDS             7506..9227
                     /locus_tag="JXV47_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HAX1487396.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            9392..10534
                     /locus_tag="JXV47_001344"
     CDS             9392..10534
                     /locus_tag="JXV47_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAX1487397.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            10550..11761
                     /gene="thiI"
                     /locus_tag="JXV47_001345"
     CDS             10550..11761
                     /gene="thiI"
                     /locus_tag="JXV47_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HAX1487398.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            12334..12981
                     /locus_tag="JXV47_001346"
     CDS             12334..12981
                     /locus_tag="JXV47_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAX1487399.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     gene            13374..16019
                     /locus_tag="JXV47_001347"
     CDS             13374..16019
                     /locus_tag="JXV47_001347"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HAX1487400.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            16329..17642
                     /locus_tag="JXV47_001348"
     CDS             16329..17642
                     /locus_tag="JXV47_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HAX1487401.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            17632..18285
                     /locus_tag="JXV47_001349"
     CDS             17632..18285
                     /locus_tag="JXV47_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAX1487402.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            18340..19032
                     /locus_tag="JXV47_001350"
     CDS             18340..19032
                     /locus_tag="JXV47_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HAX1487403.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            19182..19382
                     /locus_tag="JXV47_001351"
     CDS             19182..19382
                     /locus_tag="JXV47_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAX1487404.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(19636..21315)
                     /locus_tag="JXV47_001352"
     CDS             complement(19636..21315)
                     /locus_tag="JXV47_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAX1487405.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(21317..21529)
                     /locus_tag="JXV47_001353"
     CDS             complement(21317..21529)
                     /locus_tag="JXV47_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HAX1487406.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            21922..23652
                     /gene="efrA"
                     /locus_tag="JXV47_001354"
     CDS             21922..23652
                     /gene="efrA"
                     /locus_tag="JXV47_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HAX1487407.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            23649..25409
                     /gene="efrB"
                     /locus_tag="JXV47_001355"
     CDS             23649..25409
                     /gene="efrB"
                     /locus_tag="JXV47_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HAX1487408.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            25504..25701
                     /locus_tag="JXV47_001356"
     CDS             25504..25701
                     /locus_tag="JXV47_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487409.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            25854..26339
                     /locus_tag="JXV47_001357"
     CDS             25854..26339
                     /locus_tag="JXV47_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HAX1487410.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(26443..27036)
                     /gene="clpP"
                     /locus_tag="JXV47_001358"
     CDS             complement(26443..27036)
                     /gene="clpP"
                     /locus_tag="JXV47_001358"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HAX1487411.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            27216..27743
                     /locus_tag="JXV47_001359"
     CDS             27216..27743
                     /locus_tag="JXV47_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HAX1487412.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            27834..28571
                     /locus_tag="JXV47_001360"
     CDS             27834..28571
                     /locus_tag="JXV47_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAX1487413.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            28575..29492
                     /gene="miaA"
                     /locus_tag="JXV47_001361"
     CDS             28575..29492
                     /gene="miaA"
                     /locus_tag="JXV47_001361"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HAX1487414.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            29494..30723
                     /gene="hflX"
                     /locus_tag="JXV47_001362"
     CDS             29494..30723
                     /gene="hflX"
                     /locus_tag="JXV47_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HAX1487415.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT        10151 a         5258 c         6561 g         8769 t
ORIGIN      
        1 ttttattatt atgatgaatc aagctttctg tttttgtcac gtatgttgta atctttacga
       61 aagagtagag ttggctactc ataatcaacc atacttccca tcatcgctaa atacgaaata
      121 aatcagcatt cctacaccaa tcaaagcaca agctgcacca agaaaaggga tgacattccc
      181 aaagttatct gtattcataa gtatgccacc acccacaaac aaaaagccgc cagcaatcag
      241 gtttttcatt ttattcatct cctttcttac gttatagtat ttccttcttt caatgagtat
      301 tttgaaagct atcttattgt atgatgttct tctaggcctc ttctttatta tacaggccat
      361 tttcgttatc tcatagaaat attccttttt atctgaaaac tattgtatac cgtatgacat
      421 ttttcttcat gaagttgtaa gtatattctc attcaaatga aaatttcatc atagaagaga
      481 ttgtatttct aaattcttaa gagtaaaata cgaagtataa cttggatttg gaaggatgat
      541 tggatgaaag ctattacgcc tgatatgaca acaaaattta acaaacagtt tcaagcaaat
      601 atcaaacagc aggcattgca gcgggcagtt gtgaagaacg gaattactgc ttctgctgaa
      661 aatgtttcag cacatgtgga gaatacaccg gtattttcta tagatttggc tacggggaaa
      721 gtggctaatc aaatgcaatc ggggcgttgc tggatgtttg ctgcactgaa cacattccgt
      781 cataagatgc tgaatcaatt ccatttaaaa gagtttgaat tatcacaaaa ttacactttt
      841 ttctgggata aatatgaaaa ggcaaattat ttctatgaaa acatcattgc aacaggaaaa
      901 gaggcaatcg atagccggaa agtagctttc ttactcgcta ctcctcaaca agatggcggc
      961 caatgggata tgatcgtttc attattccaa aaatatggcg ttgtgcctaa atcggtgatg
     1021 ccggaaagtg cgaatagttc aaattctcga gatttgaata actacttgaa caaattactg
     1081 cgtaaagatg cagtagtgtt acggaaaatg gttgctcaag gagaaacatt agacgctatt
     1141 gaagaaaaga aagaagaaat gctagaaagc atttataact tcttagctat ctcattagga
     1201 acacctccaa aagaattcga ttttgagtac cgcgatgaag aaaagaacta tcatcttgac
     1261 cgaggactga caccacaaat tttttatgat aaatacatcg gtgtaaaatt agatgattat
     1321 gttagcgtga tcaatgcacc aacaaaagac aaaccattca atcgttctta tacagtagag
     1381 atgctaggaa atgtcgttgg cgggaaagaa gtcaaatatc tgaatgttga tatggaaact
     1441 ttcaaaaaat tagcgattgc tcagcttgaa gaaggagaat ctgtttggtt tggttgtgat
     1501 gtaggtcaat cttctactag aactagtggc atcatggcct tagatgctta ttcaatggat
     1561 gatctatttg atacggattt tacaatgact aaagctgaac gtttagattt tggagaaagt
     1621 ctgatgaccc atgcgatggt attgaccggt gttgacttag tagacgggca atcaacaaaa
     1681 tggaaagtcg aaaatagctg gggcgaaaaa gttggaaaga atggcttctt tgttatgagt
     1741 gatgcctgga tggacgaata tacgtaccaa atcgttgtaa gaaaagattt attgacgaaa
     1801 gagcaattaa atgcgttcaa tgaagaacca attgttctat ctccgtggga tccaatgggt
     1861 gctttagcat agacgagtat ttcaatgaag agtatgtagt aaagataaaa agagctggct
     1921 taagccagct ctttttatct ttaaagtcca ttccctgttt tttatggtcc ctgtgctata
     1981 attctaaata aaggataagg attggaaata atccttttat cattaaaaat atgatgacga
     2041 agtagaataa aattgggagt aggggggaaa gtcatggata tccaaactgt tttatctgat
     2101 ctgaaattaa atggtaaagt gattccagtt gttggtggcg atgttaatca gacctatcgt
     2161 ataaaaaccg aacatcgtgc ttatttttta aaaatccatc cgaatgtaaa aaaaggattt
     2221 tttgaagcag aagtagacgg attaaaagaa ctgtcagcat tcgtacgtgt accggatacg
     2281 tatatgctag gtgaaacaag tgaaggcgct tatttgttaa tggaatggat cgagccggga
     2341 aaaggggatc aacgagatct tgctgcagct ttagctaatc tccatcagca aacagcgcca
     2401 caatttggtt ttcgtaaaga taactatttg ggtacacttg ttcagaaaaa ttcttttgaa
     2461 gaagattggt ggactttttt ctttaaagat cggcttgaat cccagatttc tttggcagaa
     2521 gaaacgaatc gatggaatgt acagcgtcaa gaaaagtatc tgcgatttaa agaacgtgta
     2581 ttgaaatcgg ttgaaccaaa aaagatcact ccacgcctct tgcacggaga cctgtggagt
     2641 ggtaatgtgt tctttgacca gcaagggcat ccagtttttg tcgacccagc tgtttcttat
     2701 gggaatcggg aacaagatat tgcaatgagc cagttattcg gtggtttccg accggaattt
     2761 ttagatgctt atcaaactat atttccatta gaaaagggat ggaaagaccg actgccgatt
     2821 taccagttat attatctttt ggcacatttg aatatgtttg gagaaagtta cggttcccaa
     2881 gtagatcaat tactagaaaa tttttaagag gagggcgtgt ttttggcaaa aaaatatacc
     2941 aaaaagcatg aagtttcata ttatgagtgt gacatcaacc aaacgatgac atttccttcg
     3001 atgttaggag tagttatcaa aacgtctgaa gatcaaagcg accagttggg aagaggcagt
     3061 gaattcgtca atagctttgg acttacttgg gtcatcacga attattccat ggagattaat
     3121 cgtctcccta gagtcggtga agtaatctca gtaacgactc aagccatgga gtacaataag
     3181 tttttctgtt atcggaactt ctggatccat gatgaagatg ggaaagaatt agtcaaaata
     3241 gaatctgttt tcgtattgat ggattttgtg aatcgaaaaa tgagcagtgt taatgaagag
     3301 atcattgctc cttttgagag tgagaagatc aagaaaatca agcgtcagga aaaaattgaa
     3361 aagattgatt cgggcttcat gttgccatat cgtgttcgtt tttatgatat cgatagtaat
     3421 cagcatgtta ataatgcgat gtattttaat tggatcattg acgtattagg atatgacttt
     3481 ttgactacgc atgttccaga aaaagtaatt attcgatttg ataaagaagt agagtacggg
     3541 aatgagatcg aaagccattt tgaacaaatc cctatcgaaa atggtgtcaa aacaaaacat
     3601 gaaatccgaa tgcaagaaca gctgtattgt gaagcaaata ttatatggaa aaataaataa
     3661 aaaagaggtt gtgacagaag ggggcaactt caagaaataa gaagaaattt acgaaaattg
     3721 tttctcaaat ttttgtaaat tttcgactta gttttcgaag aagctatttt tgtcacagcc
     3781 tctcttttta agtttagcta ttagataatg atgtttagtt ttggataaac gaaatcaatt
     3841 cttcacccga caaaccatag tttacagcaa tcaatagttt taaacgtgct ttttgactat
     3901 taatactgtt acagaaaata atccccattt tttctagttc ttttcccccg ccttcataat
     3961 cataaacagg ctctgcgatt ccattgaaac aacgagaaac aagtactaca gggatttttt
     4021 ggacaagaag cttttccaaa gcagctaagg cttgtggagg gagattcccc gcacctaaag
     4081 cttcgattac caaaccgtct actttcgtat gggcgatggc ttccaataag tccccttgca
     4141 tcccagcata tgctttaacg atcgggatag tcccatctac agcggaaatg tccagtcgct
     4201 ttgtttctaa aagttcctgc aagaataaaa ttcgattctt agttactaag ccgatgggac
     4261 ccaatgtagg tgttcggaaa gtagcaacat ttgtggtatg ggtctttgtc acgtagcgtg
     4321 cagaatggat ctcatcgttc atgaccacca aaaccccctt atctagcgct tcttcacaac
     4381 ttgcgacacg aatcgcactt tcaaaattat aaaggccgtc acttccaagt tcattacttg
     4441 aacgcattgc cccagtcaaa acaattggta atttgttgcc aatcgttgta tcaagaaaaa
     4501 aagcagtttc ttctaatgta tctgtaccgt gtgtgatcac cactccggat atacctgatg
     4561 cataagcgga caagatacgt tcttttaata ccaacatgtg agaaggcatg atgtgtggtg
     4621 agggaagatt gaagatatct tcaactaata attctacatg cttggggatt gtgatttctg
     4681 catctaataa tgggtttgcc acatcaggac taacaccgcc cgtgagcatg ttttctttca
     4741 tggcgatcgt tccgccggtg tgtagtacaa gtattttttt cattttacag acttccttac
     4801 gaataatttt gcatagccgt taaatcttat tgtatactat ataaaagagt tttgctatca
     4861 gtgaagaata acgaatagcc taacttatca taaaaaagct gaccttatta aaatggaaaa
     4921 gactcaacct tgacctccta atacaatgga gtatctggtt gagtttcttt tacaagaaag
     4981 cagccaagga aatcaatcac gaaggtggcc ggaaatgatc agaatcggat taacatcgtt
     5041 taaagaacat gacaaattaa ctggtaaaaa gaataacact ctttatgaat atgcagggtt
     5101 tctaccctta gtggaattag atactgccta ttatggaatt ccccgaaagt cctcagttga
     5161 gaattggata agtgaagtac ctgaatcatt tcgctttgta gtcaaagtct atcaaggaat
     5221 cagcggtcaa ggagactgga agccttatta tcagaccgaa gaagagatga ttgcgcattt
     5281 tttagatgtt atgtcgccaa tggtagatgc tggaaagatg ttttgctttt tagtccaatt
     5341 cccctcatca ttcaaatgta cgaaagaaaa tgtccagtac ttgcgcaaac ttagaaagtg
     5401 gtttgagggt tatcctgttt ctatagaatt gcgggattat tcttggtaca gcgatgaatt
     5461 tcttgaacgt acaagaaact ttatgtctag agccgctttt tctttagcca tcatcgatga
     5521 gccacagttg ctgaatacaa cgattccttt tgatccattt gtcaccaatc cgaactttgc
     5581 tctttttcga ttccatggta ggaatgcgca aggatggcaa gcaaatgata aagagtggcg
     5641 taaaaaaaga acgttatatc gttattcaga aaaagaactg caagaactag cacatgaagt
     5701 caaagtagtt gattctaaga caaaagaggt aggtgtgatt tttaataata attctggtgg
     5761 tgatgcggct gaaaatgcat tagcactgca aaaaatatta aatatcaagc cagatggact
     5821 caatccaacc caaatggatc tgttttaagg gcttatttta ttcaagaaag gggcgaagtc
     5881 tatgatcaaa gctatttttt ttgatattga cggaacattg gtcaccaatc gttcaaaagc
     5941 gttggaatca acaaaacaag caattgaata tgctcggaaa aacggcattt tatgcggtgt
     6001 agcaacgggg cgcagcccag taaagatcaa agaaatcatt gatgaattgg aattagatat
     6061 gtatgtcgtg tataatggtc aactggtttt tactgcagat cgcacgatta tcgaccaccc
     6121 ttttgaacaa aaagtattgg aacatattgt tgaatttgca gatgagaacc atcgacaaat
     6181 cgtttttggt gcgagaaatc ggttagatgg atcaacgacg atgctattag gacaatcgat
     6241 ttttatcaag cgactagtca gctttttacc gcgtaaattc ccggtacgtc tgatgaaaaa
     6301 aatcctccag gtttttagcc ctcaccgaca aaaggatcgt tatgaaacgt tagagatatt
     6361 aaaagaacca atttatcaat gtatattgct cagtccggag tcagaacaga aaaagttaga
     6421 acatcgcttt cccgagtgta cgtttcagcg ttcaaatacg tatactgtag atatcatccc
     6481 aaaaggtggt tcaaaattac taggcatcca agctttcgca aatgctgtcg aaattgaaat
     6541 ggaagaaatt atggcattcg gcgatcatta caatgatatc gagatgctga aaggtgtagg
     6601 aattggagtg gccatgggga atgctcagat cgaagtaaaa catgctgcag actttgtgac
     6661 tcaatcaaat gaagaagatg ggatatacga aggactgaaa cacttcggtc tgatttatta
     6721 gtcaatgaaa gaaggaaaaa atcagtatgg aagcagagac accttttcaa aaagtagaaa
     6781 cattccacaa aacttttgat ccaagaagac cagagatacc cacggctttt acagaaaatg
     6841 aagctcatac acgtgctgcg ttcaaaatag aagaacttgt tgaatttgtt gcagctactt
     6901 cacctaataa agaacaactg catgaagctg ttatgctgct gcacgaagca ttagataaag
     6961 cagaagaaaa aatacttggt aaaacacagt ggggaagtga tccgctggtt gaacaagtag
     7021 atgcactgac agatatcctt tactttactt atggttcttt ttcattacta ggaatagtgc
     7081 ctgatcgaat attcgaaatc gtccatcagg caaatatggg gaaattattt ccagatggaa
     7141 aacctcatta tgaccctgta acaaataaag tgttgaaacc tgaaaactgg cagatggaat
     7201 atgctccaga acctaaaatc gcggcagaaa tccaacgtca gattcaagaa gcgattgcta
     7261 agaagaaatc cgctgatata ggcatgtgca caaatgaaaa agagtgatca gagtttcact
     7321 atttttgtta tctttatacg atggaaaaac aaaagatttt cgtttaagtt agtgaatgca
     7381 tgaaaatagt atgctataat ctagaataga tgtcttttgc acgagagacg tattatttgg
     7441 atttatgcca agcagaacgc catctgttgc ataaaagatg catactgaaa acggaggaac
     7501 cataaatggg aaataatgtt atcatcggaa tcgtcattgc aatcattata gtcgccattg
     7561 tcgtcttttt ggttagttac ttgatgaaga aaaaaaacca agatcgattg gatgccttag
     7621 aaaaacgcaa ggaagaatta tttgacttgc cagtgattga agaagtcgat gatgttaaaa
     7681 aaatgcatct ggttgggcaa agccaaaata cctttcgtga atggagtcaa aaatggaatg
     7741 acatatctac ttcctcgttc gctgaactag aaagtcaaat tttcgaagtg gaaaacctca
     7801 atgaaagttt tcggttctta aaaggaaaaa aagcagttgt tgaagcagaa gctacaatgg
     7861 accaaatgga gaaacaagtg acggaaatcc gtgaaggtct aaaggaattg cgggaaacgg
     7921 aagaacgcaa ctcactagct gttcagcagg cacttgacgt ctatgaagaa ctgaaagaaa
     7981 aagtcagaga agacgagcat gaatacggac cagctctttt tgaattgcaa aaacagatca
     8041 aagtgatcga aaaagaattt acgcagtttg tgactttaaa cacttctgga gaccctgttg
     8101 aagcccgcga ggttttggat aaagcagaaa aacatacgta tgaagtggaa gctctgatga
     8161 aaaaaattcc accgctgtat gaggagctcc ataccacttt ccctgaacaa cttgaagaaa
     8221 tcagtgatac ttacgagaaa ttgatggaag aacaatatgt attcccagaa gaagatcttg
     8281 ctgaagatat cgcaaaagta agtcgaagaa ttgaaaattc attagccaat cttgaaaaaa
     8341 cagaagttga aacggtcgaa tttgaaaacc gtgaaacagc tgatttgatt gattcgttat
     8401 atgatatctt agaacgggaa atggaagctc agagatatgt aaaaactaac caatcaacga
     8461 ttgcagagta tatcaaacat acaacaaaga ataaccgtca attattgatt gagctggatc
     8521 acacatctca aagctataca ttgaaccaca atgaaattgg ccgtgtacga ggtttccaaa
     8581 ccgaagtgga agaaatggaa cgtcaaaatg aacagatgat tccacagatc cgtcaacacg
     8641 aaattcctta ttcagaagtg cgcacgttct ataaaacagt cttcaaagtc ttagaagata
     8701 tcgaaaagca acaagtagag atcgacgact cattacatga attgagaaaa ggcgaaaaag
     8761 aagcgcaaga aaagatcgat acattcgaat tcaaattgcg cagtttgaaa cgttttgtag
     8821 aaaaacaacg tttgcctggc ttgccgaatg attacctaga attctttttt gttgctactg
     8881 accgtattga agaactaagt gttgtcttga ataaaattcg agtaaacatg gaagaggtca
     8941 atcgtttagt tgctctatgt gaagaagatc tagaattatt agataagaag acacatgatt
     9001 tagtagatgc agcagcatta acggagcaaa tgctccaata tgcaaatcgt tatcgtcata
     9061 cacacgaaga agtgagagaa gcaattgata aaagctacta tttattcaat aaagaatatc
     9121 actatcaaga agcattagac gaaatcggta cagcattaga gcgagtagaa cctggtgctt
     9181 tcaaacgcat cgaagatttt tattttaatc atccagactt agtataaagc aaaaaagtta
     9241 gtaaaccagc aagagcaaga cggattattg tcttgttctt gtcttttttt gtatatttga
     9301 aaattgaaac aagtgaaaat ttcacctgct cttgaaagca ccttggacaa ccgttataat
     9361 agaaaagaat ttcaaaaaag aggggtttct tatgatatat tttgataaca gtgcaacaac
     9421 cccaatcttt ccgcaaagct tagatgcata tgtaaaaacc agtcagcgga ttattgggaa
     9481 tccatcaagc ttgcatgatt taggcaatca agctaaccgg ttgttgcagc aagcaagaaa
     9541 gcagatcgct gatttgatcc atgtagaacc agaagaaatc tattttactt caggcggaac
     9601 agaaggagat aactgggtat taaaaggaac gatgatcgaa aaaagagaat atgggaatca
     9661 tatgatcatt tcaggagtcg aacatccggc cgtcagcgag acagcagaac aattaaaaga
     9721 attaggaatc gaagtaagta tcgccccagt ggataaacgc ggatttgtac gtgtcgacga
     9781 attgaaagaa ttaataagaa aagagacagt attagtctct gttatggctg tgaataatga
     9841 agtaggatcg attcagccca tccaggaaat cagtgatctt ttggatgatt ttcctaaaat
     9901 tcatttccat gtagatgctg ttcaggcgat tggaaaagta ccattctcgc aatggttgac
     9961 agaaagagtt gattttgcaa cattttcagc tcataaattc catggcccac ggggaactgg
    10021 tttcatttat tggaaaaagg gtcgtcgttt agcaccatta ctgacaggtg gagggcaaga
    10081 aagaaatcag cgaagtggga cagaaaatgt tccaggtatt gtggctatgg ttaaagcttt
    10141 acgtttatca ttagagataa aggaacaaaa acctgagcag acacaacgct taaaagtagc
    10201 tctaatcaat gcgttgaaga cgtatgagaa agtgacgatt ttttcagaag gaactgacta
    10261 tgcaccgcat attttatgtt ttgctctaaa aggaattcgc ggcgaagttc tcgtccatgc
    10321 cttagaagaa aaacaaatat ttgtttctac tactagtgcc tgctcctcac gtaaacatat
    10381 ggcaagcagt acattgcacg caatgcatgt accaaatgat ctggctacat ctgctgttcg
    10441 aatcagctta gatgaaaaca attcgcttgc agaagtcgag caatttatga ttattttcaa
    10501 gcagctttat aagaaatttt ctgcaatcaa ttaaaagagg agtgttcttg tgaaatacag
    10561 tgaaattatg gtccgttatg gggaactttc gacaaaagga aagaatcgaa aaagctttat
    10621 catgcaacta gcacaaaatg tcagacaagc tttgaaagac tttccagaaa tcaaaatcca
    10681 tgctgatcgg gaccggatgc atcttttatt gaatggcgca gacgggcagc tagttattcc
    10741 aaaactagca aaaatatttg ggatccaaaa tttctctcca agtattcgtg tagaaaaaga
    10801 tgtcgaagtt ttgaaacaag ctgttcaaga catcatgaaa gaaatttata ctgggaaaga
    10861 aacatttaaa attatcgcta aaagaagcga tcaccaattt gaattgacaa gtaatgaatt
    10921 gaatcaaaca ttaggtaatg ctgtttttga tattttcccg catatccaag ttcaaatgcg
    10981 tcaaccagat attccattac gtgtagagat tcggcgtgat ggcgcttatc tatcgtatga
    11041 aacgatcaag ggagctggag gattgcccgt aggaacaagc ggaaaaggaa tgcttatgct
    11101 ttctgggggg attgattctc ctgtagcagg gtactttgcc atgaagcggg gagtggaaat
    11161 tgaagctgtt cattttgcta gtccgccgta tacaagtgaa caagcactgc aaaaagcaaa
    11221 agatctaaca gccaaactag caccttatgt gggaacgatc cattttatcg aagtgccatt
    11281 taccgagatt caagaagaaa tcaaaaagtc agtgccacaa ggatattgga tgacaattac
    11341 tcgtcgaatg atgttgcgtt tgaccgatga aattcgccgt attcgtcatg gtttagtcat
    11401 tttgaatggt gaatcattag gtcaagtggc ttcacaaact ttgcaaagta tggtggctat
    11461 caatgaagta acgaatacgc caatcattcg gcctgtagcg acaatggata aacttgaaat
    11521 cattgaagta gcagaacaga tcgatacatt taatctttct atccagcctt ttgaagattg
    11581 ctgtacgatt tttgctcctc cacagccaaa aacacgccct caactggaaa aggtccatca
    11641 atatgaagag cgtttagcaa tagatgaaat gatccaacga gcactagctg gcttgaagat
    11701 ggaagagata caagcagaat cgtctaatga aaaaactgaa gaattttcag aattgctata
    11761 agaggttatg aaaatagtgt tttgaccaga gtattagaga aacaaaacga aaaaatagct
    11821 ccatgtattt taccgttttt gaactaatgt cgaagattag ctgattgaat accatttatc
    11881 aagaagttat ggaaaagccg gttctttttt actaactgaa aaataaaatt ttatttagag
    11941 atcaagctac agttgataaa tgatataaaa aagagaattt cccatgaaat agcgaggttg
    12001 tgacagaagt gggcagcttc aagaaataag aaggaattta cgaaaattgc ttttcaaatt
    12061 tttgtgaaat ttcggcttat ttttcgaaga agttacttct ggaacaccgt gtatcagagg
    12121 ttgcgaaaaa gctgccctgc atcaagtaat aagaacagcc aaacaaaaat agttcctcat
    12181 attttacgtt tggttgagct tattaccgca gatgcaagct tttgaacacc gttttatttg
    12241 tctcacaccc ttttccttcc tacttgtaac cttgctcccg tgttagaaac atgttacact
    12301 aaatatgtga aattattaac aaggagcgtc gttatgcgag aaaaaacaga tacactgcca
    12361 aaagcaactg cgaaaagatt acctttatat ttacgctact tgaagatgct ggatgactca
    12421 ggtataagta gaatcaaatc aaatgagttc agcgaaatca cccaaattcc ttctgcaacg
    12481 atccgcagag acttctcgca attaggcgag ctaggcagaa gcggatatgg ctatgatgtc
    12541 ccttttctta tcgatgtatt caataatatc cttaatacta aagaagaaaa acgaatcgca
    12601 ttagtaggat atggaaatct tggcaaagca ttgaaacaca acaattttag aagaaatgaa
    12661 aatctaaata tcgtgtgcgt ctttgataat gatccagcac tgatcaatcg agtaattgat
    12721 ggagaaatga tctatccgat tgatcgtttc gcggagatag ccaaagcaaa aaatgtgaca
    12781 gtagcaatct ctacggtacc aagtaaatat tcacaatctg ctattgatga aattgtcaaa
    12841 ggaaatgtaa ccgctatact taattttgcg cctgacagag taactgtccc agcttatgtc
    12901 aatgttcaat acattgattt gacaaccgag ttgcagacgc ttatttactt tgatgagaat
    12961 tactcagaag ttttttctta ggaaaatttg agtaggctta ttgatcttgc gagaactcgt
    13021 cgtaattctt tcaaaaattt tttagtacta aatgaagtgg ttttttcacg accacttgtt
    13081 gactaaaaaa aaaaaccatt gtagaatgaa gcataacgct gaacaagagg agtaactggc
    13141 acattcattc ttagagagag aactatctgc tgaaaggttc tcaatgacaa ccagtgaagg
    13201 tagcttggga gtttctgtct tgaatggagt agagatagac gagtcgtgat cgttaactca
    13261 cttgagaggc aataatgatt gattattgca atttaggtgg taccgcgtaa atcatacgtc
    13321 ctagaatacg aaagtatttt aggacgtttt ttagtttaaa ggaggaaaac agcatgacgg
    13381 aagaaaataa cctatcaaca aaatataatc cgcaagaagt tgaagctgga cgttatcagc
    13441 attggttaga acaagatttg tttaaaccga gcggagataa aaaagcaaaa ccttattcaa
    13501 tcgtaatccc gcccccaaat gttactggaa aacttcattt agggcatgct tgggatacga
    13561 ccttgcaaga tatgctgatt cgtcaaaaga gaatgcaagg atatgatact ttatggctgc
    13621 ctggtatgga ccatgcagga atcgcgacac aagcaaaagt agaagcgaag cttagagagc
    13681 aagggatttc tcgttatgat ctaggtcgtg aaaagttcat cgatcaagtg tgggaatgga
    13741 aagaagagta tgcgagccac atccgcgaac agtgggctaa aatgggctta tctttagatt
    13801 acagtaggga acgttttaca ttagatgatg gattatctga agcagtacgt aaagtttttg
    13861 ttaccttata cgaaaaaggt ttgatttatc gtggtgaata tatcatcaac tgggatcctc
    13921 aagcacgaac agctctatct gatatcgaag ttattcataa agatatcgaa ggcgcctttt
    13981 atcatatgag ctatgaacta gcagatggat caggcgtagt agaaattgcg acaacccgtc
    14041 cagaaacgat gttgggagat acggcgattg ctgttcatcc agaagacgag cgttatcaag
    14101 cgctcatcgg caaaaaagtg attctacctt tagtcaataa acaaatccca atcattgcag
    14161 atgaatatgt agatatggaa ttcgggacag gtgtagtaaa aatcactcca gcacatgatc
    14221 caaacgactt tgaggtaggt aatcgtcatg atcttccacg cgtaaatgtt atggatgatg
    14281 atggtacgat gaatgaacta gcaggaaaat atgctggaat ggaacgtttt gctgctcgta
    14341 aagcaatcgt gcaagatctg aaagaaatcg gtcgattgat taaaatcgat acgatgatcc
    14401 acagtgtggg tcattccgag cggacaggtg tcgttgttga acctcggctg tctactcaat
    14461 ggtttgtaaa aatggcgccg ttagcgaaaa aagccattga taaccaagaa acagatcaag
    14521 cagtggaatt cttccctcca agattcaatc aaacgttttt acgttggatg gaaaatgtcc
    14581 atgattgggt aatctcacga caattatggt ggggacatca aattcctgca tggtatcaca
    14641 aagaaacagg tgaaatgtat gtagggatgg aagcaccagc ggatagtgaa aactgggtac
    14701 aagatcctga tgttttagac acttggttta gttcagcttt gtggcctttc tcaacaatgg
    14761 gctggccaga tacggaaagc gaagattata agcgatactt ccctactagc actttagtaa
    14821 ccggttatga catcattttc ttctgggtaa gcagaatgat tttccaaagc ttggaattta
    14881 ctggcgaacg tccatttgag aatgtcttga ttcatggatt gattcgtgac gaacaagggc
    14941 ggaagatgag taaatcatta ggtaatggaa tcgatccgat ggaagtaatc gaaaagtatg
    15001 gagcagatgc tctccgctgg ttcttatcga atggttctgc accaggacaa gatgtccgct
    15061 tcagctatga aaaaatggat gcttcttgga actttatcaa caaaatctgg aatgcttcac
    15121 gtttcgttat catgaatatc gaaggaatga ccgtagaaga gatcgattta tctggagaaa
    15181 aatcagtggc tgaccggtgg atccttactc gtttgaatga aacgatcgaa cgagtaactg
    15241 agctatttga tcgttttgaa tttggtgaag caggtcgaca actgtataac tttatctggg
    15301 atgatttttg tgactggtac atcgaaatga gtaaagaagt actttatgga gatgatgctg
    15361 tttcaaaaca aaccacccgt agcatcttag tccatacact tgatcagatc ctacgtttat
    15421 tgcatccaat catgccattc gttacagaag aaatatggga acatattcct catcagggaa
    15481 attctctagt agtggcagaa tatcctgttg tacgtccaga gtttgatgat gaaacagctt
    15541 ctaaagggat ggaagtattg aaagaattga ttcgagccgt tcgaaatatt cgttcagaag
    15601 tgaatacacc attgtctaaa ccaattacgt tgctaattaa aacaaacgat gctaaaatcg
    15661 atcaattttt agttgaaaat acaagctata tcgaacgctt ctgtaatccc gaagagttga
    15721 cgatatcaag tgagatcact gcgccagatc tagcgatgtc agctgttctg acaggtgcag
    15781 aaatcttctt gccgttagca ggattgatca atattgaaga agaaatcaaa cgattagaaa
    15841 aagaactgga aaagtggaca agcgaagtaa aacgtgtcca aggaaaactt tctaatgaac
    15901 gttttgtttc taacgcgccg gaagaagtag tagaggcaga gcgtgcaaaa gaaaaagatt
    15961 atttagagaa gcaaacggct gtcaaagaac gaatcgaaag tttgcgtact attcaataag
    16021 aatagaaaaa gagagtgtga aatcagctag ctattactaa aagctagctg attgaacatc
    16081 gttacaggaa agagtttgag cctcactctt agcttcgatt cataaggaga tgtgacataa
    16141 attttgtcgc atctcttttt tagtctactc ttattatgta ggagaaggag ggaggtggat
    16201 catgtatcaa gagtcaataa agtagttgat aaaatcgttc ctctctctgt ttcttttctc
    16261 tttgtcatac ttttattttt cttatgtgtt ctatttgtta taataaaaga gaaatggggg
    16321 aattgttgat gacgattgaa gaagcaatag aatggatcca tagtcgatta ccatttggtt
    16381 cacgtcctgg ccttgaccga gtcgaagctt tattagaagt ggtagggcat ccagagagaa
    16441 aagtaaaaac gatccatatc gctggaacaa acggaaaagg ttctactgta gcttatttga
    16501 gaagcctatt agaagaggct gggctgacag taggtacatt tacttcacct tatatcgaaa
    16561 cgttcaatga acggatcgca atcaatggca aaagcattcc agacaatgat ttgatccagc
    16621 ttgtaaaaaa atatcagcca ctgatcaaac aacttgatca atttgaagca gtagctggta
    16681 ttactgaatt cgagacatta acagcaatgg catttgatta ttttttgatg aagaaagtgg
    16741 acgtagcgat tatcgaagtt ggcttaggcg gcttattgga ttctaccaat gtagctgtac
    16801 caatgctgac gggaataaca acgattggac ttgatcatac cgaaatactt ggagatacaa
    16861 ttgaagaaat cgctgcacaa aaagctggaa tcatcaaaca aggcgttcca gtagtaacag
    16921 gaaatattgc cccagaagct tttactgtca tccaacaaac agctaaagca aaaaatgcac
    16981 cgctttatgt atacggggaa aattataaaa taaactatct gcatcctgat gagatgtggg
    17041 gagaagtatt tgaatttttt aatgaaatag gaaagatccc tcaattaacc actccgcttt
    17101 tagggcaaca tcaagctgaa aatgcaggag tagccatcga attgtatttt gtttactgtc
    17161 aattggaaaa gctgcctttc cgagaaaaag atgttttgaa gggattgaag aaatctcgat
    17221 ggccaggaag aatggagcgt ttgagtaacg agccattagt tgttttagat ggtgcccata
    17281 atacgcatgc aatgaaccgg cttgttgaga atttgaaaaa agaattcaaa ggatatcaaa
    17341 tcaacatttt gttttccgcc ttacgaacta aaaatgttag agaaatgcta gaacgattgc
    17401 agcaagtacc aaatgtccat atttatttga cgacctttga acatccaaaa gccatcgaat
    17461 taagtgaagt atcagattta gcaagtgaga gagtatcaat cgtttcattg tggcaattcg
    17521 gattagcaga tatattggaa aagatgacaa atgaagacgt attagttgtg accggttcac
    17581 tttatttcat ttcagaagtt cgccatttat taatacaatt aggaggagat catgaagtat
    17641 aatgcagtga tttttgacat ggatggtttg ctgttcgaca cagagttagt gtattacgaa
    17701 gccacacaag tagtagcaga caagatgggt tttccttatg ataaagacct gtatttaaaa
    17761 ttcttaggtg tttcagatga agaagtatgg gcgaattatc atatgatttt ctcggaattt
    17821 ggcaaaacaa gtgtacaaag attcatagat gattcatacc aggaaacgct tgaacgtttt
    17881 tcgcaaggag cggtacaaat gaagcccggt gtgttggaac tcctctcttt tttagaagaa
    17941 catcagattc ccaaagttgt cgcttccagt aaccaacgag cagtcattga acttttattg
    18001 aagaagaaca atctgtttga acgatttgag acgattgttt ctgcagaaaa tgttcaacga
    18061 gcaaaaccag acccagaaat tttcttgtta gctaatcaga agctaggtac agcgaagaaa
    18121 gaaacattga ttttagaaga ttcacaaaat ggtattttag cagcttctgc ggctgagatc
    18181 ccggtagtca tggtaccaga tctgcttcca ccatcccaag aattgatcaa aaaaacagct
    18241 ggggttgttt cttctttaca tgaaatccct gcattgttaa aataaaaatc catctctttt
    18301 cgtatcttat tttagataag atagaaagga gatgtttttt tgggaaaacg attgatcaaa
    18361 gaagtaccta ctagctcttt accaagggaa cgtatggaaa tttatggcgc ggaagcttta
    18421 tcggatcagg agcttttggc aatcttactg cgtaccggtc aacaccctta tagtgtgatg
    18481 tcgattgctg gaaatctgtt aaaaacgttt ggaggactgg cctctttacg acaggctact
    18541 ttgcatgagt tagaagagat tcgagggata ggacgcgtga aagcaatcga aatcaaagcc
    18601 ttgatcgaat taggtcgacg aattcagacg gatcatgaaa gagcggctcc accggttcgt
    18661 accagctacg aattggccca gcaattgatt ctggaaatga aagatcacaa acaagaacat
    18721 ttggtttgta tttatttgga cacgaagaat caagtgatct taaaaaaaac agtgttcatc
    18781 ggttcgctga atcagtcagt cgctcatcct agagaaattt tccattatgc tgtacgttat
    18841 tgtgcagcaa ggatcgtttt agcgcataat catccttctg gtaatgttat tccatcgcag
    18901 caggatatga attttaccaa aaggatacaa aagtgtggag aaatgatggg gatcactgta
    18961 ctggaccact tgatcatcgg acgcaaacga tattttagtt tgagagaaga aggaatgatg
    19021 gaagagaagt aagttgcttt cttgcaaaaa aaatgaagca agtgtacaat tatattgtaa
    19081 ttttgtttgg gaatagaagt tgaaacatct gttgcacctc tatcgtacac gagcaatgtt
    19141 acaatttaaa ttagtgcttt tggcacgagg aggatattat tatggaaaac ggaacagtaa
    19201 aatggttcaa cgctgaaaaa ggatttggat ttatctcacg tgaagatgga agcgacgtat
    19261 tcgttcactt ctcagctatc caaggtgacg gattcaaaac attagaagaa ggtcaagcag
    19321 tgactttcga cgttgaagaa tcagaccgcg gcccacaagc tgcaaacgtt gtaaaagctt
    19381 aattttatct gtaaatcaaa ttgatggtag acatcaattt ttacgagaga acaaagcgag
    19441 taacaaaaat acctgccaca agagacaatt tctcttgtgg caggtatttt tttgtatgaa
    19501 aaagtaaata aatttaagag gctatgaaag agccaccttg tatcaaggaa taagaacaaa
    19561 caaaaatggc ttctcatgtt tttcatttgt tttctcttat attcaggaca aggtgctgat
    19621 ttcataacct cttatttatt cttcatctgg tgtcattacc attggcaaaa tcattggatg
    19681 tctttctgta cgttcgaata agaaaggctg aagcgcgcca gtcatcgctt ctttcaattt
    19741 atattctgaa cagtcaggtc cattcaaaca ttctcttaaa gcgtggaata agattcgctg
    19801 agcttcattg atcatttctc ctgattctcg catgtagaca aatccacgag agagaatatc
    19861 tggaccagcc aagatttctt ttttcttgat atccactgtc gcgacagcta atacaagacc
    19921 ttcttctgaa agcaggtgac ggtcacgtaa aacgacatta ccaatatcac cgatcccgct
    19981 accatcgata tacacatctc cagccacaaa atgcccagca ggacgcgcag aatcgctagt
    20041 taacgctaaa acatcgccat tttccatgat gaagcagttt tctgcaggaa cacctacatc
    20101 ttgtgctaga gaagcatgta ctttcaacat gcggaattct ccgtggacag gaataaaata
    20161 ttttggcttc atcaaacgaa gcattaattt ttgttcttct tgtccaccgt gaccggaagt
    20221 atggatgtta ttgatttttc cgtgaatcac ttctgcacca gcttcagaca gcaaattgat
    20281 caaatgattg acacttgttg tattaccagg aataggtgaa cttgaaaaga tcactgtatc
    20341 gtctggctgg atttggattt gacggtgagt accattcgcg atgcggctca acgcggccat
    20401 cgcttctcct tgagaacctg tacataggat catcgtttca ttggcaggca agcgattgat
    20461 ttcgtgtgca tctacaaatg tgccgtctgg aactttgata tatcctaaac gttgaccgtt
    20521 gacgatggca ttttccatgc ttcgtccgaa aacagcgatt ttacgaccag ttgccacagc
    20581 ggcatctgct gcttgctgca aacggaagat gttagaagca aagctggcaa aaatgatacg
    20641 tccttcgatt tttgaaaaga tcttcaaaat agaatgccca atcgtttttt ctgatttagt
    20701 aaatgttgga atctcagcat ttgtactatc agataaaagg cacaagactc cttcttcccc
    20761 gatacgagcc attttatgca agtttgctgg ttcgccaaca ggagtgaaat cgaatttgaa
    20821 gtctccagtc gctacgatat ttccagaagg tgttttcacc acgatcccta atgcatctgg
    20881 gatactatgg gtcgttctga aaaagctgac agaagtcttt ctaaaacgga tgatcgtatc
    20941 ttcattgatc tcatggagct ctgcatctcg aagcaagcca tgctcatcta atttgtttgt
    21001 gatcaacgct aatgcgagag gaccagcata gataggaata tttgcttgtt tcagcaagta
    21061 gggtattccg ccgatgtggt cttcgtgccc gtgagtaatc accaaggctt ttactttgtg
    21121 taagttttgt atgatgtagc tgtagtcggg aatgacatag tcaattccaa gtaaatcgtc
    21181 ttccgggaat ttgatcccgg catcaatcaa aatgatttca tcttggaatt gtaccccata
    21241 cgtatttttc ccgatttcac ctaatccacc aatagcaaag acgcctgtct cgttattttt
    21301 gatggaaagt ttcatattaa aactccacta atgagaaatc agcattttct ttttcgtact
    21361 ctagatgact tccttctaga agttgaacga attcaatatt gtatggggta ttttcttcca
    21421 cacgttggcg agcgtctaca tcgctttttg cctcaatgta aagagatttt gtttcttccc
    21481 gtttagggtt gcgtactttt gtttcttgat aataaacttt atagatcatt gttttgtctc
    21541 ctttatctgc gtaaagcagt gatttagcta gttgattttt ttagacaaca caaaacgagg
    21601 ggacaagcca cctggttttt catatgcttt gactagaata ctggattcga gtcaaagaga
    21661 caagcctcgt ttttgcttat ctgttcggat attttttcaa ccgtaccttc tgtataaaaa
    21721 atatacaaca attaattgtt attctagcat aaaacagcaa ataagtatag aaatcaacta
    21781 gattgaaaga aaaaatcaat gtttatcatc ccgctataat cataatgact tttttatgag
    21841 agaagtgttc tattaatagg ctcgttgtgc tatcattttt agtaatgaaa atgtaacaaa
    21901 agattaaaag gagatgagaa agtgaaacta atgtggcatt ataccatgcg ttataagaaa
    21961 ttcttgtttt tcaatttcat atgcgtattt ggttttattt tgattgaatt aggacttcct
    22021 acgattttag cacgtatgat cgatgtagga atccgcaatg atgattttga ttatgtgaag
    22081 caacaaggga tatttatgat cgttattact gtaatcggta ttattttgaa tatcttgtta
    22141 ggttattttg gttcgaggat tacgactaat atcgtagcag atattcgaga tgatttgttc
    22201 gaaaagatcc aaagttattc gcatcaggaa tacgaaaatc taggcgtatc ttcattgatc
    22261 actcgtacaa caaacgatgc ttatcagatc atgttgttcc tgcaaaatat tttacgtatc
    22321 ggttttatgg caccaatgat gttcattgtc agtttgtaca tggtcatgcg tacaagtgtg
    22381 acactcagtt tgtatgtagt aggtgcatta cctttactat tattggcagt cgtagcgatt
    22441 gctaaggtgt ctgaaccgtt atctaaaaag caacaaaaaa acttagataa aatcaacagt
    22501 atcttgcggg aaaatctttc aggattgcgt gtgattcgtg cattcgtcaa tgaaaagttt
    22561 gaagaaaaac gttttgctgt agtcaatgag aattatgctt ctagttcaaa aagcttattc
    22621 cgtttgatgg ctgttgcaca accgggtttt tatttcttat ttaatatcgt aatggtattg
    22681 atcatctgga gcggggcagt gcaaatcgat gcaggcgagc ttcgtgtagg agatttgatt
    22741 gcgtttatcg agtatatatt ccatgccttg ttctcattca tgttatttgc tagtgtgttc
    22801 atgatgtatc caagagcagc tgtttcagct ggacgtatcc aagaagccct agatgccaaa
    22861 ccttcgattg tagaagatcc aaatggtata tctgatacaa aaactaaagg gtatatcgaa
    22921 tttcaaaatg taacatttgc ttatccaggc cattcgcaag agccagtgat acgaaatgtc
    22981 agttttacag cctctccagg agagaccgtt gcttttattg gaagtaccgg tagcggaaaa
    23041 tctacgttga tccaattgat ccctcgcttt tatgatgtga gtgaaggaaa gatcttgatc
    23101 gatggagtag acgtgagaga ttatcggcta agcaagttgc gagataagat tgggtttatt
    23161 ccgcaaaaag cgctgctatt tactggaacg attgcagata atttgcgata cgggaaagaa
    23221 gatgctacgc aagaagaaat ggaacgtgca gctgagattg ctcaagcttc agaattcatt
    23281 tctcgaaaac cagatggatt taatgaacat ttatcagaag gtggttccaa tttttcaggt
    23341 ggacaaaaac aacgattggc aatagccaga gccatcatac gccgtccgga aatctatatt
    23401 tttgatgaca gcttttctgc attagattat caaacggatg cgaagttacg tgctcgtctg
    23461 aaaaaagaaa cgacagaatc tactgtattg atcgtagcac aacgtgtggg aacgatcatg
    23521 catgcagata agatcatcgt attaaatgaa ggagaagtcg tcggtatggg gacgcatcgg
    23581 gagttgttgg aaaaatgccc gatttattat gatattgccg cttctcaatt atcaaaggag
    23641 gaattagcat gaaaaaaacc ttttcttcct taaaacgttt agctcgatat atcagaccgt
    23701 atcgtgagac ttttctttta gtgatcctat ttacagttct gacagtggct ttcaacgtgg
    23761 ctttgccata tgttacagga cttcctacta cagaaatcag ccgtaatatt gccaatggcg
    23821 aatcaatcaa tttttcttat atattcaaat gtctcatttg gatcacagtt gttggaatag
    23881 ggtattgtat ttcgcaatta ctttctggtg ttttgatgac aaatgtcgtt caaagtgcca
    23941 tgcatgattt gagaagagac atagaagaaa aaatcaatcg tcttccggtt tcatatttcg
    24001 ataaaaacca gcaaggaaat attttgtctc gtgtgacgaa tgatgtagat gcagtcagcg
    24061 gtgctttaca acaagctttt attggtatcg taaatgcgat attgggaatt acgttggctg
    24121 cagcaatgat gttttatatc cagccgatga tggcgctgat ctctatgatc atgattccaa
    24181 catcgatctg gatctcaaaa cgagtgatca atgcttcgca gaaatatttt caaagcatgc
    24241 agaattctct tggtgagcta aacggctacg tccaagaaaa tatgacaggt tttagtgtat
    24301 tgaaagtata tggacgcgaa aaagaaacat tggaaggatt caaaaaagtt aatcacagct
    24361 tgaaatactt tgggtttcgt gcagcattca tttctggctt gatgatgcct ctagttcaat
    24421 taactgccta tgctacttat attggtatgg ctgttctagg aagcttttat gttattactg
    24481 gggcgatcgt tgtcggtcaa ctacaagcat tcatccaata tatttggcaa atcagtcagc
    24541 caatggggaa cgtgacacaa ttgtcttcag ttttgcaaag tgcatcagcg gcaacgaaac
    24601 gtgtattcga gattttagat gagccagaag aaaaagaaaa caaagtagat gcttcactgc
    24661 cagaaacgat tttaggagat gtgacattcg atcatgtcga ttttgcatat gatccgaaga
    24721 aaccattaat ccaagatttg aattttgaag tgaaagctgg tcaaaccgta gctgtggtcg
    24781 gtccgaccgg tgccggcaag acgacattga tcaatctatt gatgcgtttt tatgacgtag
    24841 acaaaggagc aataaggatt gatggaatcg acaccaaatc aatgagtcgc agtgatgtgc
    24901 gttcgctatt tggtatggtc ttgcaagatg catggcttta tcaaggaacg attgcagata
    24961 atatccgctt cggaaagctt gatgcgacag attatgaagt agttgatgct gcgaaaacag
    25021 caaacgtaga tcattttatc cgaacgatgc cagatggata tgatatggcc atcaattctg
    25081 agggagacaa tgtgtcttta ggacaaaaac agttgctgac gattgcccga gcagtggtct
    25141 ccgatcctaa aatcttgatt ttagatgaag caacaagttc agtagacacc cgtttagaag
    25201 cgttgattca aaaagcaatg gatcgcgtga tggagggacg gacaagtttc gtcatcgctc
    25261 accgtttatc gacaatccgt gatgcagatc tgattctagt gatggatcaa ggtcagatca
    25321 ttgaaaaagg aacgcatgag agtttattgg cacaaggtgg attttatgaa aaactgtata
    25381 acagccaatt tgctgaggaa gcagaataag tcatataaga ataaaacagt ttaaaactta
    25441 ttttttgttc tctattcttg ataatggtaa agtaaagtta tcaagaaaag tgaggacacg
    25501 gagatggaac agtttttaaa tgaaaaaatt actgaagcca aaagagaagt tgatcgttta
    25561 acgcacgtct gtcagacgaa gccttttgat tcagctgatt tttttgaaaa tgagtttcaa
    25621 atcgaacgct tggcagcaca aatagaagtg tacgaattaa ttttaaaaaa agtaatagaa
    25681 gaaaatatag atgtacaata aaaacaggta aaacgtcagt taccagatac tgtaaataga
    25741 catctggcct gagcaggttt tacctgtttt ttttcttatg aaataaatat atgctatgat
    25801 acctttattc aataggatta gtttctacaa aaaatgaaag gagaaaaata aatatggaac
    25861 ggtttatagc atcaaatgcc acagtgattg gtgatgtgac attgtcagaa gatgtgacga
    25921 tctggtatca agctgtttta cgcggggaca gtaattggat aaaaatagga caaagaacga
    25981 atatccaaga tggtacaatc atccatgtcg atcatgatgc acctgtagat attgcggaga
    26041 atgtgacggt aggacatcag tgcatgctac atggctgtac aatcgaaaaa ggggcgctga
    26101 tcgggatggg gaccacgata ttgaatcatg cggttattgg tgagaatagt ttgattggtg
    26161 ctggatcatt agtaacagaa ggaaaagtta ttcctcctaa tgtcttggct tttggtcgcc
    26221 cagctaaagt gatccgtcct ttgacaaaag aagaaataca aaaaaacaaa gaaaacatcc
    26281 agcattatgt cgagataggt cggatgcatg cgcaaggaaa attcaaggag caaagatagg
    26341 cagtagcatc cataaaataa aaaaggatgg tcagtttgag ttgaccatcc ttttttattt
    26401 ggtttagata agagagctta aaaaagcttc ctttgaaaca gattaattta atgaagaact
    26461 gttttccatg acttcatcga tcaatccata tgcttttgct tgttcagctg tcatatagtt
    26521 gtcacgatct gtatcttttt caatcacttc aagcggttgt ccagtgcgtt cagctaaaat
    26581 tttgtttaag cgttcgcgtg tttgcaaaat atggcgtgcc gcaatttcga tttcagttgc
    26641 ttgcccttga gcgccgccaa gaggttgatg gatcatgatc tcagcatttg gtaaagcaaa
    26701 tcgtttacct tttgtaccag ctgtcagcaa gaagcttccc attgaagcag ccatacccat
    26761 aacaattgtt tggacatctg ctttgacaaa gttcattgtg tcgtaaatag ccatacctgc
    26821 tgtaactgaa ccaccaggag aattgatata aagatagata tctttttcag aatcttgagc
    26881 gtctaagaaa agcaattggg cgatgatcga attagcaaga tcatctgtta cttggccgct
    26941 taacatgatg atacggtctt tcaataaacg tgagtagata tcgtaagctc tttcacctcg
    27001 tgaagattgt tcaatgactg taggaattaa attcataata gagttcctcc ttgatttcgt
    27061 ttagaaatag tgtaccataa tttagtttct aatacctaaa atgtagtata catttttggt
    27121 caaaaaaggt caaataaaaa acttaggcaa attagtcgca taaacccgct ttatggtatg
    27181 ataagcagag aaacaaaaca aggaggaaca acagattgat agttggtatt actggcctta
    27241 tcggagtgct gacaggtgct gtagttgtct atatcggcat gatactgcaa atgcgtcact
    27301 tggaaaataa agaacagcgt agacgtgaat tggaattgaa agtcaaagaa atcgagacgc
    27361 tgaatcaatt aaataaaaag atcaacgaga tcttgcaaaa acggacaacg ctgatggaag
    27421 aatatgtcag ctttgatgca tttgatgatt gttatatcac gattgacgat tttgcgtatc
    27481 tccaatcatt ttcagcgcaa aatagttttt atctgccaaa ttatatttta gacgagctat
    27541 ttaagaatat ctcccatcga aaagtgattt tatctccaga tgaaacaatg aagattggtg
    27601 gatatgctta taaaggcgga cgcgtgattt tagagaattt tacggatagt ctgactgaaa
    27661 tgatcaatga aaaaaaagct cagttgaaga ctatgacgcg ccagccgatt ggtttcttct
    27721 cgaaagatga tgtttggagc tgatattttg aagcattgcc gttgcacatg agagcgtggt
    27781 aatgctttct ttttttctta atgatacaat agaactgaac ggagtgaaga aagatgttac
    27841 aaatctatgc ccatcgcgga agcagcggca cccacccaga aaatacgctt cctgcatttg
    27901 cagaagctgt acgagtaggt gcagatggta tcgaactaga tgtccatcta agcaaagatg
    27961 gttatttgat cgttatgcac gacgaagaag tggaccggac gactaacggt aaagggctga
    28021 ttcgagaaaa aacattggaa gaactcaaaa aattgaatgc agggggcaaa ttcagcaaag
    28081 aatttccagc agctaaagtt cctgaattga gagaagtgtt aggactgctc ctccaaaaaa
    28141 attaccgagg gatgctaatg attgaaatta aaactgatca gtatgaatat cccggtatcg
    28201 aagaaaaatt agccgaaaca ttaaaaagta gagattggcc ttttcaacat gcatattgca
    28261 gctttcattt ggattctttg gaaaaaatcg cattactgga accggagata cagctggact
    28321 tattgatgag tacttctgat aaaaagatcc aactagcagc agaaacccct tatatagaag
    28381 gagtacatcc aaaaaatact tggttgttcg aacatccagt ccaggcagct gattttccaa
    28441 aagcaattcg tgcatggacg attaacgatg aagaagaaat ggccaaatgt caagaactca
    28501 aaatagatgg aataataact gattttccgg agaaagctct tcggtggaaa caatcaacga
    28561 aaagtaggta aaatatggaa aaagtattag tgatcgtcgg tccgacagca gtcggtaaaa
    28621 cagcgctaag tgtggaactc gcacaactat ttggaggaga gatcatcagt ggtgattcat
    28681 tgcaaatcta taaaaatctg gatatcggta cagcaaaaat caaagaagaa gagatgaata
    28741 atgttccgca tcatttgatt gatgtgatcg aacctactca acgttactca gccgctgatt
    28801 ttcagcattc aggtcgacaa ttgattaccg agattgcgaa ccgagggcac ctacctatca
    28861 tagctggtgg tacgggtctc tatatccaat cccttctata tgattatcag ttaggagcga
    28921 cagaagaagc gaatcctgag attagaaaaa agtatgaaac gttagctgaa acaattggtt
    28981 cccaagcatt atggaatcag ttgaaagaaa aagacccggc agctgctgag aaaatccact
    29041 ggaacaatca acgcaaagtg ataagagctc tggaagtttt agagacgaca ggacatagta
    29101 tcacggcacc taaagaagag ccaaagcaat tgtatgatta cctcatgatt ggattagata
    29161 cgaagcgtag tattctttat gaacgaatca atcaaagagt cgatttgatg ctagcagaag
    29221 gtttagtagc agaagcgcgt aaggtgtatg agcttggaga agtccaggcc agtcaaggta
    29281 ttggatataa agaatttttc ccttattttg aagggaaaga aacattggaa gaagcaacag
    29341 aacaagtcaa actacattcg agaagatacg cgaaacgtca gttgacgtgg tttcgtaacc
    29401 gtttggatgc acagtggttt gatcttataa gtgagccaaa tcaaaaaagt cagattgagc
    29461 aaacaatcaa aaaatggctg gaggcggaat aaaatggaag aaaaagtgat catcgtaggg
    29521 gtagaaaccg aagcaaacca gcgttacttt tcagagtcaa tggaagagct agttcagctg
    29581 acgaataccg catcaggaga agtcgtattc acaattacac aaaagagacc acaagtggat
    29641 cggcaaacga ttatcggtaa agggaaatta caagaattag ttcaacaagc ggatgcgcat
    29701 gaagcggatt tgatcatctt taatcatgag ctaactccga gacagagcca actgattacc
    29761 gatgctgttg gtcttccggt aattgatcgc gtgcagctta tcttagatat ttttgcgatg
    29821 cgtgctcgtt cgaaagaagg gaagctgcag gttgaacttg ctcagttaga atacctgctg
    29881 cctcgtttag tagggcaagg gaaaacatta tctcgtcttg gcggtgggat cggaacaaga
    29941 gggccaggtg aaacaaagtt agaaacagac cgccgacata tacggaataa aatttttgct
    30001 gttaagaaag aattgaaaga agtagaagct catcgagagc gcaatcgcca aaaaagaaaa
    30061 aatagcgaga tttttcagat tggacttatt ggctacacga atgccgggaa gtcaactatc
    30121 ttgaatctat tgacacaagc ggatacttat tcgaaagatc aattgtttgc aacgttagat
    30181 ccattgacta agagatggcg ttttgctgaa ggatttgaga ttactgtaac ggataccgtc
    30241 gggttcatcc aagacctgcc tacgcaactg atcgatgctt tccattctac attagaagaa
    30301 agtcaaaata tggatctttt gctacatgta gtcgatgcta gttctccaga tcgtatttta
    30361 caggagcaga ctgtcttaaa attgatggat gaactgaata tgaaagaaat gccgatactg
    30421 actgtttaca ataaggcaga ccagatcgac ccagcgatgt tcacgcctac gctattccca
    30481 aatgtattga tttctactca gacgaaagaa ggtaagatgg cgttgatcga agcaatcaaa
    30541 cgtcagctga tggaactaat gaccccttat acactttctg tgccaagcaa cgaaggacag
    30601 aaattaagcg agttgagaag acaaacaatg gttttggacg aagcgtacat ggaagaaaca
    30661 aacgaatatg aagttaaagg gtttgcaaaa accaattcaa aatggttaag aaaaaaccaa
    30721 taaaatttta tttttttaa
//
LOCUS       DADGKS010000027        30202 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.027, whole genome shotgun sequence.
ACCESSION   DADGKS010000027 DADGKS010000000
VERSION     DADGKS010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30202
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.027"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(38..1189)
                     /locus_tag="JXV47_001363"
     CDS             complement(38..1189)
                     /locus_tag="JXV47_001363"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HAX1487416.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(1202..1639)
                     /locus_tag="JXV47_001364"
     CDS             complement(1202..1639)
                     /locus_tag="JXV47_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAX1487417.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            complement(1654..3420)
                     /locus_tag="JXV47_001365"
     CDS             complement(1654..3420)
                     /locus_tag="JXV47_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HAX1487418.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEALATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            3684..4361
                     /locus_tag="JXV47_001366"
     CDS             3684..4361
                     /locus_tag="JXV47_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1487419.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            4364..5491
                     /locus_tag="JXV47_001367"
     CDS             4364..5491
                     /locus_tag="JXV47_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1487420.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLPLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(5691..6131)
                     /locus_tag="JXV47_001368"
     CDS             complement(5691..6131)
                     /locus_tag="JXV47_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAX1487421.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAKTIEEVQMIFEHGHI"
     gene            complement(6142..8175)
                     /locus_tag="JXV47_001369"
     CDS             complement(6142..8175)
                     /locus_tag="JXV47_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAX1487422.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            complement(8177..9880)
                     /locus_tag="JXV47_001370"
     CDS             complement(8177..9880)
                     /locus_tag="JXV47_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1487423.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKKSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            complement(9974..10924)
                     /gene="manA"
                     /locus_tag="JXV47_001371"
     CDS             complement(9974..10924)
                     /gene="manA"
                     /locus_tag="JXV47_001371"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HAX1487424.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIATEPGK"
     gene            complement(10963..11988)
                     /locus_tag="JXV47_001372"
     CDS             complement(10963..11988)
                     /locus_tag="JXV47_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAX1487425.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            complement(12197..13066)
                     /locus_tag="JXV47_001373"
     CDS             complement(12197..13066)
                     /locus_tag="JXV47_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HAX1487426.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            complement(13525..15417)
                     /locus_tag="JXV47_001374"
     CDS             complement(13525..15417)
                     /locus_tag="JXV47_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1487427.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(15414..17141)
                     /locus_tag="JXV47_001375"
     CDS             complement(15414..17141)
                     /locus_tag="JXV47_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1487428.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(17157..17807)
                     /locus_tag="JXV47_001376"
     CDS             complement(17157..17807)
                     /locus_tag="JXV47_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAX1487429.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            18011..18307
                     /locus_tag="JXV47_001377"
     CDS             18011..18307
                     /locus_tag="JXV47_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAX1487430.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            18479..19099
                     /locus_tag="JXV47_001378"
     CDS             18479..19099
                     /locus_tag="JXV47_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HAX1487431.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(19191..20357)
                     /locus_tag="JXV47_001379"
     CDS             complement(19191..20357)
                     /locus_tag="JXV47_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAX1487432.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(20369..20722)
                     /locus_tag="JXV47_001380"
     CDS             complement(20369..20722)
                     /locus_tag="JXV47_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAX1487433.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLETVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            20850..21872
                     /locus_tag="JXV47_001381"
     CDS             20850..21872
                     /locus_tag="JXV47_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HAX1487434.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            complement(22311..22745)
                     /locus_tag="JXV47_001382"
     CDS             complement(22311..22745)
                     /locus_tag="JXV47_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487435.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLKKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(22855..24714)
                     /locus_tag="JXV47_001383"
     CDS             complement(22855..24714)
                     /locus_tag="JXV47_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAX1487436.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(24832..25992)
                     /locus_tag="JXV47_001384"
     CDS             complement(24832..25992)
                     /locus_tag="JXV47_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HAX1487437.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(26299..27210)
                     /locus_tag="JXV47_001385"
                     /pseudo
     CDS             complement(26299..27210)
                     /locus_tag="JXV47_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
     gene            complement(27376..28569)
                     /locus_tag="JXV47_001386"
     CDS             complement(27376..28569)
                     /locus_tag="JXV47_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002610375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAX1487438.1"
                     /translation="MSEKRRDSKNRVLRSGESQRKDGRYAYKYVDTFGKPQFVYSWKL
                     VPTDKTPAGKREDISLREKEKEIQKDLDDGIDTIGKKMTVCQLYAKQIRHRGNVKHNT
                     KLGRERLMRILEQDRLGSCPIDSVKLSDAKEWALRMKEKGLSYKTINNDKRSLKAAFY
                     TAIQDDCIRKNPFDFQLSDVLDDDTEPKVPLTPAQEESFLSFIQGDKVYQKHYDAIVI
                     LLGTGLRISELCGLTDKDLDFENRVIIVSHQLLRNTGVGYYIDEPKTQSGVRKIPMNE
                     EVYQAFQRVIKNRKGAKPFIIDGYANFLFLKQNGYPMTAVDYGGMFGRLVKKYNKSHE
                     EALPKTTTPHAMRHTFCTRLANAGMNPKALQYIMGHSNITMTLNYYAHATFDSARAEM
                     ERLAA"
     gene            complement(28653..28856)
                     /locus_tag="JXV47_001387"
     CDS             complement(28653..28856)
                     /locus_tag="JXV47_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HAX1487439.1"
                     /translation="MMNHDVPIWEKYTLTIEEASKYFRIGENKLRKLAEENPASGWVI
                     MNGNRIQIKRKQFEKIIDTLDTI"
     gene            29113..29355
                     /locus_tag="JXV47_001388"
     CDS             29113..29355
                     /locus_tag="JXV47_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487440.1"
                     /translation="MAHQPSGSAQTECVRMPYDAPPLSCGHIYQGAIRPPGKHRNGER
                     VSRFMLPGPVRQFVTIAWMSLISRRRFMASSRHTCG"
     gene            complement(29277..29510)
                     /locus_tag="JXV47_001389"
     CDS             complement(29277..29510)
                     /locus_tag="JXV47_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1487441.1"
                     /translation="MKNPNYKGIELLPLSVIEAARAGDAGAVERVLQYYSGYMNKLCT
                     RTLYDENGYPHVCLDEAMKRRLEIKLIHAIVTN"
     gene            complement(29517..29948)
                     /locus_tag="JXV47_001390"
     CDS             complement(29517..29948)
                     /locus_tag="JXV47_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAX1487442.1"
                     /translation="MDAIPRDYEARCMFDAFCKTVLRNEAKSYLAEMKRRRDREVSLS
                     SLSQADLDKLCTVDHYPSDSFTFSSHGYDLHINNELVAEAFAALPSMEQSILILHCVL
                     DMADGEIGGLVGMSRSAVQRHRTNTLSELRKQLKALMPKGG"
BASE COUNT         8479 a         6440 c         5483 g         9800 t
ORIGIN      
        1 aaaaatttcg tcacattccc ctttttcgta tcctatttta agcgacttgc ttggcataac
       61 ggttcacgtt ttgcttgata ttcccgattg ttttcggatc attgattcct gtgacttctt
      121 gaatcaattg ttccaagttt tcatggatct tcatttcatg caattgacgg ctttgttcat
      181 cttcaggatc atagtaatta aaaataatcc ccattgttgc cgtcaaatgt gggcaagtca
      241 agttatgttc ttgtagttct ctcactggac gtgtaaatct ttcttgataa cctaacttac
      301 gtaatggtgt ccgagcgaca cgtgtgatcg catcagagat atttttgttt tggaagcgat
      361 gaatgatttt ttcaatatac gcatgatgct gctctgcatc aaacccccat ttggcaatca
      421 gcaaacttcc tgtttcctgc aaaactgatt ttaattgtgc cacaactaac gcatcttgca
      481 ttgcttcatc aatggtctgg taacctaaca aggcacctgt ataagcgaca gtcgcatgac
      541 cagtattgac actaaatagt ttgcgttcga tatatggttc tagatcatct acatataaaa
      601 ccccttttaa ttggattttt ttattttttc tttggctatc gtcaatgacc cattctttga
      661 aaggttccac ttggacgaat aaaggatctt catggtgttg taatgggacg attcgatcga
      721 ctgctgcatt tggaaagccg atatatttgt cagtaaatga tgtttccgga agatatttat
      781 acacttcttt ttctagaaat gctgaaccgc caatcatatt ttcacaggca atgatatcta
      841 aagatgttgt gcttccttcc ttttctcttt cttggatacc ttttgcaatc aactcagcaa
      901 taaaaggtaa gatattcggg ccaatggcgg tagtaactaa atctgcttca gcgatttctt
      961 ggattacttt ttctggattt gtttgattgt tgattccttt gacatttttt acagtgattt
     1021 tttcttttga ttcatctgct aattcgattt cgtattcttt tctttcattt aaagcatcaa
     1081 tgatcgtgtg attcacatct acgaaagtaa tctcaaatcc attagctgcc aaaacctctc
     1141 caataaatcc tcgaccgata tttcctgcac caaaatgtac tgctctcatt tttctctctc
     1201 cttaagcaat tgctagattt tccgttactt cttctttgct gagcgcgtct gctagctgga
     1261 caacattgtc catatcactg caataaagtg cgatttgctg tacaagttgc aaatgctcat
     1321 ctccgactcc tgcaataccg aacaaaacag tcgcaatctt ttcttcttct tcggtaccaa
     1381 aatctacacc atctggtact tgaacgacac agatgccgga ttttttcaca tatttttttg
     1441 cttcatctgt tccatgagga atcgcgataa aattccccat ataaacagat aacattttgt
     1501 ctctatctac catggcatcg atatattcct catcaacgca ccctgcttct acaagcatct
     1561 gaccgcaata gcggatcgct tcttctttgg ttttaaaaga tcgattgagc tcgatcatgt
     1621 cgaatggcaa actttgcatg ctgttttcct cccttaagct gtctgtttca aatattgtgc
     1681 aatcgattcg tatttttgcg gattgaccat gctgttgact gataaatgaa tggattgagg
     1741 tgcagccatc tgtacttttt ccgctaaact ttctttggct acgatcagtg aatcaggttc
     1801 atcttttaaa tcttggatat tgacttttct taacgggata gttaaatggt tcttgtctaa
     1861 tatatctttg agcacggtca tccccattgt tgctgatccg gaacgatcat cgtggacaag
     1921 tagaatctct ttgatttgtt tgatgtttgc tgaaagaaac tcttctgctg gctcattctc
     1981 aatttcagaa actgatgttt tctgcttgct gcttaattct tgaatgattt catcatatcg
     2041 aggtgaattc aaaaagtttt ctactgagac aaaacgcgcg ctcggtgctt tttgttttgc
     2101 tctttcttgt agttcgacct gagtaacgat caatgtattc gagtcatctg tcagttggct
     2161 gattgcttga ttggtcaccg tttgaggcaa gtctgcttcc tgtacttttt ttctcaagat
     2221 cgaagcgccc atcgcacttg atcccattcc tgcatcacaa gcaaaaatga ttttttgtac
     2281 gccagagaat gtagctcctt gaggaatacc ttgggcacct ttggaagctt gcttagctgc
     2341 ctttgtctct tgaacagatt tttcgaagtc ttcatttgta tctttcgcat ccgctttcaa
     2401 aattactgca gaaataccaa acgaaacagc tgcggcaaca atcacgccca aaataacagg
     2461 aaggtaagaa ttgaacggtg tcatcgctag aatcgcaatg atcgaccctg gagaagctgg
     2521 cgctcttagt ccagcatcca tcaattggaa aatgaaactt cctgacattc ctccgcctat
     2581 aactgataag aataataacg gtttcatcat aacgtaagga aaatagattt catggatccc
     2641 gcctaaaaag tgaatgatca tggctcctgg tgctgaagat tttgctgctc ctttgccaaa
     2701 caaagtaaaa gcaagtaata cgccaagtcc tggaccagga tttgcttcaa gcaagaatag
     2761 aatagatttt ccagcctctg ctacttgttc agttcccaat ggtgtcaaaa tcccatgatt
     2821 gattgcatta ttcaaaaata agatttttgc tggttcaata aaaatacttg tcaatggaat
     2881 caaatgggca gataaaatga tctctacacc ttttgccatt gcttgagtca atgcatcgac
     2941 aactggacca atcgcagaaa aacctaataa cgctaatcca aaaccgataa gacctgctga
     3001 aaaattattg actagcattt caaaaccgga tttgatccgt ttttggaata gctgatcaaa
     3061 tttcttgatg gcatatccac caagaggtcc catgatcatc gcgcctagca tcattggaat
     3121 atctgttccg acaatcacac ccatcgttgc aattgcccca acaactgatc cgcggtcacc
     3181 agcaattact tttccgccag tataaccgat caataaagga atcagataag ttagcattgg
     3241 gcttaccatg gtagccaaag cctcatttgg taaataacca tctgggataa atagagccgt
     3301 taatacaccc caggcaatca gtgctccaat atttggcatg accatgcttg ataaagtact
     3361 gcctaatttt tgtaccctcg cttttagcga aatgttgttt ttgggaatcg tccgttccat
     3421 tttgtctctc cctctctcct tttgatactc taattgtatc cgcttactaa aaagagaaat
     3481 agtcgtactt tggcacgaaa ctttgtgcca aaggtttgag tatgtcagca aaataaaaag
     3541 atttcggtat cagaaaactt caattttaaa taaaactgtt attttaattt ttttataata
     3601 tgcaaacaat aacttttgtt agcatttaat ttagatgttt tccattctat tatgttatta
     3661 aattttatat tggaggccta tctatgacat tactgatcaa aaacatgaac atgaaacgtg
     3721 gtaaaaaacg tgtgattcga caattgaatc ttttagtaga atcaggagaa gtagctgctt
     3781 tgattgcccc gaacggattt ggcaaaacaa ctttgctgaa tggcattgcc caactgctgc
     3841 caacaactta tgatcaattg tcccttcaca acatctctcc tactgcttat acagattatc
     3901 gccggtcttt cttttttcta gaatcaacga atcagttatc cgactatcta tcggctgttg
     3961 attatttgac tttgatcaaa tactattggc agagcaaagt agaatgccaa actgttttcc
     4021 aacgattgaa gatgactgag taccttactt tgccgattgg aaaaatgtct ctaggaatga
     4081 aacaacatgt cttgcttgct gcttacttga tcagtgattc atctgtcatg ttattcgatg
     4141 aaccgttgaa cggattagac ccaggaagta ttgatatctt gaatagcctc atcagacaat
     4201 ggcagaaaga ggggaagacg attcttcttt cttcccacgc tatcgcgaat atccaatcga
     4261 tttgttctaa agcatgtttt ctaaaaaatg gagaaatcgt cacagaatcc tcaaatatgg
     4321 aagagatttt agctatttat cgtaaattat atgaggtgta actatgtctt tacttacatt
     4381 tgaacgcaat ctcttactaa aaaacaaagt aaacttttta tttcctctat tgttggtcgt
     4441 gctctttgca ttcccacttt tttttgatca taaacttgct tatacagaat tcgatgaact
     4501 gaatcataac tatgaagaga tgcaacgttt gattgaaacg ttgaaagaag atgagaatga
     4561 gaaagaattt gtggaaagtt tagagaaaag caacaaactg atcgaagcaa tcttacatgc
     4621 aaaaaacaca gggaatgtcc agcaaatggt cgaagcaact tatcattatg aaaaagatat
     4681 actggatcga ctgatttctg gtcaaagaca aggaattcca atcattgaac aacaaaaacg
     4741 tgtcgagttg ctccgttata tgaaagaaca tcagatccaa agatattcta tttttgactt
     4801 gccagcgcat ctccctttag caaattacta cgaaaatatt ttttcaggaa tgatttctag
     4861 ttttttgatt ttatgtataa ccgccttgtt tctttcttcc atcatctctt atgaaaaaag
     4921 aaagcaggta atctctctag tcaatctatt accggatagt atggtaaaga aacatagcat
     4981 ccgttttacc atttattatg gtgcagctat gctaagtctc gtgatgccat ttttgatcgt
     5041 ctctatacta gtaataatca aaaatggttt gggagacttc cgttatcctg taggaacgat
     5101 cattggtcag gagatacgaa tccttccgat gtatgagtat cttttccaga gctttctgtt
     5161 cctgttgttg tgggtgctct ttttaagtac aatcagtttt cttctatctg ctttatttga
     5221 acattctcta gtcaatcttt taggtacact tctttgtctt ttcttagcag agtatcgctt
     5281 gttttcttcg attggatgga tagaatcaat cagtcattac ttgccaactt cttatgttga
     5341 ttttcaaaat gtgatcatag gaggagatat tttctcgcca ctagcttcag aacaggttac
     5401 tttcatgaat ggtatcttga cacttggtat atggagtatc gttttattat tcataggtat
     5461 gggcactatc tatataaaaa agagctatta aaacacaaaa ataatagggg cggtgacaaa
     5521 aaccttgtca ccgtccccta tttcaaataa acggttttct agaataaata gttttcaaaa
     5581 gcttgcatcc gcagtaataa gaacctccca acaaaaatag ctcctcttat ttttatcttg
     5641 gttgaagtta ttacttgatg caaggcagct ttttttactg tgaacattgg ttatatatgt
     5701 ccatgttcaa aaatcatttg gacttcttca atggttttcg catcactgag cgccattact
     5761 tggtcgatgt ctgaacagaa aaaggctaaa tcttggagca ccgctaactg atgttctttt
     5821 tttaaagcca ctacaaataa gagtgtcgcg atttttggtt cctcttttgt tccaaagtcc
     5881 acaccatcag gcacttggac taaatagatt ccttcttcta ctacttcttc atctttgtca
     5941 gtcccatgtg gcaaggctac gaaattcccg atatagacac tcgctttttc ttgtctttcg
     6001 atcattgatt ggatatatgc cggtttgatt cccccttgtt gggtcatcca ctggccgatc
     6061 tcggtcaacg cttctttcca attttgatag gattgatcga gcaatatttt ttctgctggt
     6121 agctgtatca tcttttcacc ttcatttctt tatttcttca atcaggattt tcgctaacaa
     6181 ctgataaacg atttctttat ttcctgagcg gaagatctcg gtgttcaagt cattcatgat
     6241 gattgctcca ctgatctttc ctaaaagaat cccgtctttt tcttggattg gcgaaggcgc
     6301 cagcataact aacatacggg acaaatcgac tggctgtcta tccatccctt caatggtcaa
     6361 cggatgtttc aaattgaaaa tacaaaagat cggtttagaa atcaatgagc tggatgtatg
     6421 gaataacccc atatttgtat gaggaatacc gataggtgct tgttcatatc gcttaagcag
     6481 ccggcgatga accacctctt catccgttac tagtccttca ggaaaataag gaaataagct
     6541 gcgaatcgtt tcggaaatcg tctcaggatt atccagttct tggataaaaa aacgaccgag
     6601 taattgattg atttgatcca tgaaatgcat tgtttcctca taagtatctt ctatcatcca
     6661 ctcgttattg ctgttatacg taattttttg cctttttttc ttctcaatat gcgaaaaagc
     6721 ttcttttagc tgcttgactt catcttctag cagtagcggg gagactaaaa tatattttcc
     6781 accgtatcct ggtaaaatag atgtagaaat aacaacatca tattcttctt gtaaatcgat
     6841 tttttttaaa tcagcaatcc gatagaaatg aatttgttgg atgaagggaa aatacctttt
     6901 caatcgtagt tccaacatgc tagtagaagc taatccactt ggcgaaaatc ctgcaatact
     6961 gatattgctt tctttcggac ttcgttccaa tgaattcgca aaatgaagga ccatataagc
     7021 gatctcttct tcggataatt ttttttcttg aaaaatccgc tctactgctt tacggattgc
     7081 attcgcaact tcctcgtatt gaaccatgat tttttctaaa atcggattgg tcagtgtctc
     7141 ttcttgtaaa acggctcttg aaaacacacc agataaatga gtcaacagca ttttgtacaa
     7201 agtttcatct tcataaaaat ggacattcgt ctcttcactt acttcttgaa tcagttgttt
     7261 tactaaataa gcaagctgtg tatcgaacgt ctcttcaaag aaattctgat caaatgagtt
     7321 cgtgaagtca tttaataatc ctgcaaaaaa gacgatctca tttactggat aaagttgttt
     7381 tgtctcagaa gcgatccgtg aaaacaatcg tttagctgtc tgtagtaatt ctttgtttgc
     7441 cagactatta tatgtctcat ttgtcagtaa atgattttta gtcacacgct ccatcgtcaa
     7501 tgtcagcatc aaaaccaaat gttcaagctt tctatcactt agattggtct ttttttggat
     7561 caattcttcc ccgattactt tgcgtgcaag agatagatgt tgcggatcaa cgaatcgaaa
     7621 aaaataattc agtgatgcat cgaaagaaat actatgaaaa agttcatatt cattgatttc
     7681 taattctaat acattcgctg tcagaagccg gcggtatttt tccggtcctt cgatctcgta
     7741 tccctggttc cgaatgattt ccaaaggcag ttggcgaata ctttcttcca actgtttgat
     7801 atctgcataa aaagtggtat tactgatgcg atatgattcc atgaaatgag caagactcaa
     7861 cggctctgtc gtcagtaaca actcggctaa aatcgcgtgt tgtcgtttag cagtggataa
     7921 gtcattactt ttcccatctg tattttcttt taattgctct aatacttctt ctgatgcctc
     7981 aatgacaaat gagcctctag ctgctttttt caaagaagca tttaccgatt tcaatgagac
     8041 ttcaagatta tctaattcgc ggtaaatagt ccgtttactg accttcaata aattcatcat
     8101 tttttggata gatacaggtg acgggctact gagaaattct gctaataatt gtttttctct
     8161 gggcgataaa tacatcttat atttctccct tcacgagttt ttcgtattca ttcgtagcta
     8221 cccaatgttc aactagaact agccgaggga tcttttcttc tagctgttca gttacagcta
     8281 gttctctttg tgcgatataa atcgtttctt cttggatttt gattttttct attgattctt
     8341 ttgagataac aaactgtttt ttcgcttttt ttgctaattg acttaaaatc gtcatgccca
     8401 tagtttgtga gccgcgtctg ttgtttttat acaaaaatac aatattagca ggcgactttt
     8461 tttgttctgt gatatctgct atctcttttt tttcttcccg ctttggaaat tggatcgctt
     8521 cttttattcg tgacagcaag atatctgttt ccaaaaagtg atccagtaca tagatttgac
     8581 tttgaggtac tttttctctt gcaagacccg ctagttcatg ttgcacgata accagctgat
     8641 ttacttggtt attcaattca tagatagagc tgtatccgac agaaagatcg attttttctg
     8701 ctgctaattt ctttttcagc agggcggctc ccatagcact tgatcccata cctgagtcgc
     8761 aagcaaaaat gacggaatga atgatagatg gttccaagat ttctcccctt tctttgaccg
     8821 ttttgttctc tttttcttta tttggtaatt tcaatagtat cgctgcacaa atgaaggtca
     8881 caaatgtact gattgctatc cctatactta ccccagctag ttgtggataa ggcgcattgg
     8941 caaaaatcac gagtagtgac ccaggcgata caggtgcagc taatcccgta tctaaccatt
     9001 gaaatatcaa cgtgccgctt gccccaccag ccattacagc taaaaataga tacggtcgca
     9061 gcaagacaaa tggaaaatag atttcgtgaa tcccgccaat cgcatggatc atcaatgctc
     9121 cactcgcatt tactttttcc tgtttttctg caaaacaaag gatagaaagt aagatcccta
     9181 aaccaggtcc aggatttgcc tccatcaaaa ataaggaaga gtacccgact gtttgtgaga
     9241 attcgattcc taaaggtgtc aatacaccat gattgattgc attattgaaa aatagtactt
     9301 ttagaggttc taagatcaga ctgacaagtg gtaacagatt cattgtgact agccaagaca
     9361 caacggaggc gagcaacaag tgaacactat ttaaaactgg ttcaataaaa acgattccaa
     9421 ttatacaaat aacgctacca gtcagtccta ctagtaggtt gctgacaagc atttcatatc
     9481 cagccttgaa tttcacgtgg aatctagaaa caaattgttc atatacgatg ccggcaagcg
     9541 gcccgataat catcgctcct acgatttgtg gagcattgga acgagcgatc aaccctaaag
     9601 aagcaattgc accggcgact gccccttttt gtccccctac cgatttcccg cctgaataac
     9661 tgatcaagat gggtaaaagc agctggatca tccaatggca tacctcttct aatgtggtgt
     9721 gcaaatcgcc agacacacct tttgttgcta atgacaagat tccccaagcg ataaacagac
     9781 ttagatttgg catgatcatt tcatttaagt gatgtccagc ttttctcagt tgtttcatag
     9841 acacgcgact gctgttgttt gctttccatt tgtattccat ctttttcacc atacttctat
     9901 ttattgatgg acggatttta tgtagaaaaa gcagcaaacg aaaaaccgtc tgctgctttc
     9961 agctatctgg gaactatttg cctggttcag tcgcaatgat tgctagttca ccttggaccg
    10021 cccactcaga aacgccattt ggaataatac agcttgttcc tttttctaat ggatatgttt
    10081 ttccgtcaac gacaaggtct cctgctcctt cgattaccgt catcaatgta taaggggctt
    10141 gttttttgaa agatgtgatt cctttaatat cccactcata tacattgaaa aactcagttt
    10201 ctaaataagt gacgatcgat gaattccctt ttcggacttc tttgatttgt aattctggtg
    10261 ttttcgcagg gacagttgtt acatcgatcg attgttggat atgcagctct cttgtttgtc
    10321 cttgcgcatc ttttctgtcg tagtcataca cgcggtaagt cgtgtcagaa ctttgctgtg
    10381 tttctaaaat catgattcct ttaccaatag catggatcgt tccgcttggt acataaaaga
    10441 aatcaccttt tttaactggt actttcttca aaaggtcatc ccagcgccca tctttgatca
    10501 tctcagctag ttcttctctt gtctttgcat gatgaccata gatgatttct gcaccaggtt
    10561 cagcatcgat gatataccag cattcagttt ttcctaattc accttcatgt ttcatcccat
    10621 aggcatcatc tggatgtact tgtacagata gatcatcttc tgcgtctaag atcttgatca
    10681 ataatggaaa cactggttct gaaggatggc caaacaattc cttgtgttct gaccatagtt
    10741 catctaatct tttccctttg aattcgccat tttctactac actgacacca tgaggatgcg
    10801 cactgatcgc ccaatcttct ccgattttat cgttagggat atcaaaacca aagactgaac
    10861 gtaaacgact tcctccccaa attttttctt gaaaaactgg ttttaaaaac ataggttcct
    10921 gcataattca aactcctctc atttttcata gctattatag cattatttcg gtaataccgc
    10981 tttctctttc aaaaagtttt caacaatttc atctcgacat atgagatact ccgcacgatg
    11041 atcgacagga tgtacgcgat ttgacaaaaa tatcaacgct tcttgtgttt ttatatcaat
    11101 caagaaaaac gtacctgtat aaccagtatg aaaaagaatc gcatgaccgt cttctacatc
    11161 cttttttaag tcccatccta aagaacgata gccatttttt ttcggtgttt gatcttgcag
    11221 taaagaatca atcgtctctt cttctaaaaa acgaccatta cggatttttc ccttgttcaa
    11281 atacatttgg acaaaagtaa tgctgtcttt caaatcaata aagagacccg cgttacctgc
    11341 atgttcagcc aaaactcttg ctttcggatc atgagtttgt ccacgcaaaa cctcacccga
    11401 aggcagttgt tctgtgggaa cgattttttt ggaaggaaaa ggaagaaata agctgttcat
    11461 cattcctaat ggttccaata cttgttcttg aaagatttcc actgcagttt cttggtaaat
    11521 ttcctctagc atcaacccaa gaagaatcgt accggcatct gtatatttta cttcttttcc
    11581 tagttgctca cctggttcta gcttcaaata agcggcgatc aattcttcct gagatagctt
    11641 atctctgttt ggtatccatg ttttgatatc agaagtatgt gtcagtaaat gacgcaaagt
    11701 gattgtctga ttttcaaatt caggaagata tttatgaagc ggttgatcga gttctatctt
    11761 tccatcttct aatagacgta aaactaatga agtggttgca acgactttcg tcagtgaggc
    11821 tgcatcaaac aacagatctt ctgtcatcag ctgcttttca ggaacgactt gggcaaagcc
    11881 ggctgtaaat gtttctactt gattttcttt tatgaaggcg actgctacac ctggataaaa
    11941 tccttcttcc atctttttca aaataagctg tttcgtgtgt ggatacatct ttttctcctg
    12001 cttttctatc agattcttac agtccaagct taaagcttaa tctatgagga atcaaccttt
    12061 tttacacaaa aaaactgcgc gaaaaaccgc gcagtttccc ccggtatact attttctctt
    12121 tctatctcta gaataagcga tagtatgacc gttcataaaa tgacgagaca tgcgacaatc
    12181 gttaagaaag aaaaagttaa gcgtcgcatc gaatgtcagt tttattcttt tcttttggct
    12241 cactgacgaa ccaccattcg attcctatag catcatagat tgtgagtact gtgtgctttt
    12301 tgtctaagaa gaaatcaact gatagttgct gcaagtgagc aatcagtcct tccatgcttt
    12361 cagtatcgat catgaatttc agaaaatcaa gtccaatcac ttcatctgta ggcaaatcaa
    12421 ttgcgcctcc gctagcttct gtcaaaccaa catggaaatc tccttcattc aatacatgga
    12481 tgccctcttc ttcattatgt accttcaaac caagtacatg attaagaaat tggcgttctt
    12541 ttgttaagtt agtaacattt aaatggattt tttcaaaata agaacctgtt gatagtttac
    12601 tgaatttttc ttcagatttt cttaataatg cttcttgatc cattgtttct ggaatttctc
    12661 tttggtcgtt cttattctct tcatggtaaa tttccaattc attctcttct gggtctacga
    12721 gcaaaatccc catacgtcca tgatcttcta aagcttcttt gattggataa ttcattttac
    12781 ggatacgaca aaggatatct gccatttctt ctgtgctagg gataatcaat gaaaaacggt
    12841 tcagcttttt gatcaccccc atgtgatcat tcgctctagg actttcttcc agcagcaaca
    12901 tttcacttcc agcttcttct gttcctaaaa tggctaattc gttttcttct cttttcaaat
    12961 caaagccaac aacgttcttg taaaaatcaa tcattttatc tcggtctttc acccgaatgg
    13021 ctacactttt taaataggtg gcagccccca attgaaaatc tttcatattt cttgctcccc
    13081 tctacgtcaa gctttatttt aacgatggat tcttcttctt tcaagcaata actttgattt
    13141 tgttaaaaaa aatgtgagaa aattcgcatt ttgcttgttt tttgtaaatt aatgagtaaa
    13201 aactcttata aaaagaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
    13261 acaaaaatag ctcctcctat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt
    13321 tgaacaccgt ttaaggaaga ggttgtaaaa tcagcggttt gacctgagta ttagagatac
    13381 aaaacggaaa aatagcttct catattttgc cgttttttga gctaataccg aaggacagct
    13441 gattgaacac cgtttattcg gaaaaaggga ctgtgacacg acttttgtca cagcccctaa
    13501 aaaaaataat aaatttgtac tattctatga agcttcttct tcagaaaact gactgttata
    13561 aagatctgca tagaatccgt ctttttccat caatgtatcg tggtttcctg tttctacgat
    13621 cgaaccatga ttcatcacaa taatgttgtc tgcatcgcgt attgtagaca agcggtgagc
    13681 aacaacgaaa cttgtccggt tttccaatag gcggttcatc gctttttgaa tcagtatttc
    13741 tgttcgtgta tctacactag atgttgcttc atcaaggatc aggacatctg gatttgctaa
    13801 gaatgcccgc gcaattgtga ttagctgacg ctgcccttgc gaaatattgc ttgcatcctc
    13861 gtttaataca gtgttatatc cttctggcaa tttacgaaca aaatcgtcta cgtgagcagc
    13921 tttagcagcc tcaatgattt gttcgtctgt tgcatcgtcg ttcccatatt tgatattgtc
    13981 atagatactt cctgtaaaca gccaagtatc ttgcagtacc attgaaaact gtgcgcgcaa
    14041 ttcatcacgt gaaagatcac gggtatctac accatcgtaa cgaatactac ctccagaaac
    14101 atcgtagaac cgttcaagaa ggttgatcag tgtcgtcttc cctgcaccag tcggacctac
    14161 aatagcgacc atctcaccag gtttgacatc caagttaaaa tcagtcatta gcaagttatc
    14221 tggtgtgtag ccgaattgaa cattttcaaa acgaactttg tatggtgtat ctttttcttc
    14281 tggaaggcca gatttttcat tggacatctc ttcttcatcc aacacttcaa atacccgttc
    14341 ggctgaagca actgttgatt ggatagtgtt catcaaactt gcaagttgag tgattggttg
    14401 agagaactgt gttgtatatt gcaagaacgc ttgaacatcc cctaatgtca tgttcccatt
    14461 tgcaactttt actccgccta gtacagcgac gaacacatag cctagatttt taacgaaatt
    14521 catcaacggc atgatgattg ccgaaataaa ttgagctttc caaccagcgg catacagatt
    14581 ctgattttct ttttcaaata cttcctggtc tttttcagta tgattgaatg ttttaacaat
    14641 ggtatgacca ccatatgttt cttctacttg gttattcaat aaacctaaac ttttttgctg
    14701 atctgcgaaa aacacttgtg atttcggcgc tacgatcatc acgatgatca agcttaaagg
    14761 gatcatcaat aacgcgacta acgtcaattg ccagctgatt gaaagcatca tcacgatgac
    14821 cccaatcaat gtgactgcac tagttacaaa ttgagtcaaa ttttgctgca gcgtgcttgc
    14881 gatgttatcc atatcattga ttgctcgaga catgatatcc ccatttgtat gtgtatcata
    14941 ataggaaatc ggtacacgat tcattttggc ttccaaatca tgacgtaatt cataaactgt
    15001 tcgttgggaa acacgtgtca taataaattg ctgtaaaaag ttgaatacag cagaaatcaa
    15061 atacatcacg attactgtcg caatgatctg cgcgatttta tcaaagtcta tcggaaattt
    15121 tgttacttgt tggccttgtt gcatctgttg agcgccagcc attacacctt tgaatatttc
    15181 tgtggttgct ttccccaaga cctttggtgt ttggatttgg aagatcacgg ctgctattgc
    15241 tagtacaaat acagcgatga tcgcaaccat acgtttagac atatagccaa acaatcggcg
    15301 taccgttccc cagaaatttt taggcttttc accttttaca ccgagatttc tgccaggtcc
    15361 accatgtcct ggaccgcctg ctggtccatg agagggacgt gtgtttgttt tactcatgct
    15421 aagtcctcct ctcttagttg tgaatgaacg atttcttgat aagtttcgtt tgttgctaat
    15481 agttcttcat gtgttccttt gccaaccagt tttccttcat ctagcacaag gatcatatct
    15541 gcatccatta ctgtacttac tcgttgagca actaaaacgg tgatactttc tttcatattc
    15601 gttttcaatg cttggcgaag attggcatcc gttttgaaat ccaacgctga gaaggaatca
    15661 tcaaacacat agatatctgc tgttttgact aatgcccgtg caattgccag acgctgtctt
    15721 tgtccaccag agaagtttcc tcctccttgt tccacatggc tatctaagcc atcttccatc
    15781 tctgaaacaa aatctttagc ttgtgcgatt tctaatgctt tccaaatcat ttcatctgtt
    15841 gcatccggct taccatactg catattgtct cggatcgttc cagagaacag aactgctttt
    15901 tgaggaacaa agcccattaa ttctcgcaaa ttatattgag tcatgtcact aatgtccgtt
    15961 ccatttattt ggatcgaacc agattcgatg tcatataatc gagggatcaa attgactaag
    16021 gtcgttttac ctgaaccagt cccccctatg attgcgacga tctcgcccga cttggcttgg
    16081 aaatcaatat cttccaatgc aagtttttct gctccatgat atcgataatt gacatgattg
    16141 aaggccaatg ttgcgttttt tccagcaaaa gaaactgttt taggattttc agggtcatgg
    16201 ataccgattt tttcatccaa cacttcatta atacggtcag ctgaagcttg tgcacgaggc
    16261 accatgataa aaatagcgga aagcatcata aagctgatca agatctgcat cgcataagtc
    16321 ataaatgcaa tcagattacc gacttccaaa gtcatatctg ctatgtagtg tccaccaaac
    16381 caagtgattg ctacgtttgt accgctcatg atcaatgtca tcattggcat catcaatgcg
    16441 acgatcgtat taactttgat tgccgtattt gtataatctt tattcgctaa atcaaaacga
    16501 ttttcttcaa agcgtgtctt atcgaatgct cgaatcactc tgacccctgt caatccttct
    16561 cgaaatacca ggtttaaacg gtcagttttc ttttgcatac ttttgaataa tggaacagca
    16621 aagtacatga ttccgccgat caaaataatc attactggga tgacaactaa gaagattttt
    16681 gtcaactgat gatctttttg ataagcaagt atgctcgcgc caatcaacgt gattggtgca
    16741 ttgatcatca tacgtaaaaa catttgtgta accatttgga tttgagtcac atcattggtc
    16801 gttcttgtga tcaaagaggc cgttccatat ttatcaaacg catcttttgt cagactctct
    16861 gattttttat agacatccgt acgcaattgc ttacccagtt tctgtgattc acgagtagca
    16921 aaaaatgtat ttgcgatagc agctaagata ctgatcaaag aaaagccgat catcacaaaa
    16981 cctgtatgcc aaatataatc gacatctcct tgcgctaccc ctttatcaat aatattggag
    17041 gtaagtgtcg gcaaatataa atctgccagt acttggatca ccatgaaaac tgcagctgca
    17101 attgctgaag tcaaggagat ccgttttacg atttttagca tctagttccc ttctttctat
    17161 ttatatactc cgtttttcag ccaagaaagt ttcaaattga attcactgat tgcttgctct
    17221 actgagtaat cttcagatgt tgaaaataag cgatacgaat gcgcaattgt tgtaaataca
    17281 gtattcatca ctaattggat cagtaattcc aattcatgat cattttttac tttcagcttc
    17341 gtccgatcga tcaattcaag caactctttt gcatcttgtt tgtgttcttt atgtggatcg
    17401 tgaggcgttt tttggcgact cgtatgagga gcgacttttc ttgaggcacg gtaatccatg
    17461 ttcataaaca agttacgata aaaagaagca ttctcgcctt ccaaaatctc ataaatcatt
    17521 ttagaaaaat aggattcgaa tcctttgaat agatcaccat cggattcttt cattagttgt
    17581 aacatatctt tagagctgtc acgtctcatt gtctcaaagt aataaaaata aagatcctct
    17641 ttatcttcaa aatactgata gaaactgcct ctagggatat ccgctaattt gacgatatta
    17701 gcaatcgaag cttcttttaa gggtactcta gaaaactcga ttctcgcagc ctcgattagt
    17761 cttttttgtt tttctttagg caaatggaaa aatgtctgtg tcggcatatg gatcctcctt
    17821 tctttcaaga tgacacattg tcatatgacg ctgtgtcatt ataacacctc ctacctgttt
    17881 tgcaagacat ttgcatagtt tttttcatta tcatccgata cattaaaaaa gtgataagag
    17941 gaatccttcc atttgaatta atgagagttg cccattaaaa tagccacata ctaaacaaag
    18001 gatgagataa atggcccaat caattagtgt ccaagacttc aataaattgc ctctcgatgc
    18061 tgacagcatc gttttagata caagaaatac cttagattac acaaaaaacc acttaagcca
    18121 ctcgctttct atccccgctg ctatcttgcc aagacaatta aaaaatctag atccaaagaa
    18181 actttattat attctaagct atacaggcag gcgatcagaa gcattagccg atcaacttac
    18241 tgctaatggt tttcgtgctg tttatatcat tggtgggatg gaagctcttc agtcgagtgt
    18301 tgcttgaata ttgcttgtta gattcaaaag aggctgtgac aaaaaatcgt gtcacagcct
    18361 cttttatacc ctgtcttttt ttagttattt attcttcaac cttatcaata tgacttgata
    18421 gccttttctt tttctcatag ttataacaat catagcaata aaaggagaag gtaagcatat
    18481 ggcatctgtt ttagtagtca aaggtcatcc cctaactgca gaagaatcgc gcacagttaa
    18541 ggcattgacg tcttttttaa caagttataa agaaaatcat ccagatgatg aagtgactgt
    18601 tttggaactt tatcgcgatg atattccgga aatcgatgaa gaattattat caggttggga
    18661 agcattacgt gctggtgcag aattcacttc cttatcagaa agtcaacaac aaaaaattgc
    18721 tcgtttcaat gaattgactg atcagttcct tgctgctgat aaaatcgtta tcgcaaacgc
    18781 cttatggaat ctaaatatcc caacaaaatt aaaagcttgg ttcgataccg tcaatgtagc
    18841 tggaaaaacg ttccgctata cagaaaacgg gccagaagga ttagtgacag gtaaaaaagc
    18901 actgcacatc caatctaatg gcggtgtata caacggacaa gactttgcct ctcaatatgt
    18961 aaaaggtatt ttaaactttg taggcatcga tcaagtagat cagctattca tcgaaggaat
    19021 cgattatgac cctgaccgtg cagatgagtt gatgcaaaat gcattagata aagctgctgc
    19081 tttaggtaaa tcattttaaa aattgagata aatgcataca aaagagacag aggaaaaaat
    19141 cttcaaagca gcatttgtac cttggatatt ttcccatctg tctctttttg ttattctttc
    19201 tgctttttca acggattttc ttcataaaga gaagagattg ttgtgtacca ttcaaaaaca
    19261 tgagtaatca ctactttagc tgctgcataa acaggaatcc ccaagatcac accgatgatt
    19321 ccgaacaatt tcccagaagt cagcagaact aataaaatcg ttactggatg gattgctaac
    19381 tgattcccta gtactaatgg agagatcaag cgtccttcta ttgtctgctc tactgcaaaa
    19441 acgatcagta ctttgatgat catgaatgga cctgctacaa tggctaaaaa gatagccgga
    19501 atcatcgcta aaaatgatcc taagtaaggg atcaggttca aaaaacccgc aataatcccc
    19561 aacgtgacag catactctaa accaatgacc gcaaaaccaa tcataaacat gattgccaca
    19621 gcaaaagcca cagttagttg tcctcttata taagaagaaa cttgactatt catttcactc
    19681 agcacattca acgtcggttt ttgcatgcgt gtcggtaaaa atttgacaaa ataaggtgct
    19741 aattgtttac cgtctttcaa tagataaaat aagataaacg gcatcgtcag cagagccact
    19801 aaaatagtcg ctaccgcgcc gacaaaactt ccaagactct gaactgtact cttagatata
    19861 tcttggatca tatcgcctgc cgaattcatg aacttatcac ctgctgtttc caactgttcg
    19921 cgaaattggt tgaacagcgg gtcccgcaaa atctcggtta atttattatc aatcgtatct
    19981 acatattgag ggaagttact gatgaagctc actgtttgtt cctgaatctt agggatgatc
    20041 actacgctcc cccatgcgat tagtgcaaca accaaaacaa acagcccaat gatactgtaa
    20101 agccttggta cttttcgctt ttcaaagtaa tcaactaccg gattcatcaa gtaatacaag
    20161 attcctgcta aaatgatagg cagacctacg attgctaaaa attgccagat tggtgcaaac
    20221 aaatatgaaa cttttgtaaa taaaaagacg atcagcaata ttaacaatac aacaagtaag
    20281 gctgtgacta cttgattatt taaaaaccag cgccaaaacc acgataccgg tctgttcttc
    20341 ttattttttc cttccataat tcctcctgtt agttataaaa aatttggctt cccaaaccaa
    20401 tagcaggcag tctatgcgga tgaagataga ttccatttgc aatttgtcct tcttctggac
    20461 aagcatcaaa aatcaatgat acgtgagcta ctgtctctaa attcccattg gccatcggac
    20521 cgacataatc gatcgtatat acctgatcat caaaagcaat tgttccgcct gctttcaaag
    20581 aaaaaggttc gtcttttgat acttcttgaa tcaccgaata ttttcgtaag gcagctgttg
    20641 ctgttttatc gaacaaaatc agcatgggtt cttccttgtt tattgcttct gtcccaattt
    20701 ctgtaatctt tgcctgaatc attgcactct ctcctttaat tgctttcaaa aacagtataa
    20761 cacattctca ttctttagcc gtgtggaata attatgtgat agaataaaaa cgaaaactat
    20821 ttcattacaa ttaggaggaa tcagctcata tgatcgaaaa gataatttta ggaacctata
    20881 cgcgtcgcga aagtaaagga atctatacga tcgaccttga tacagaaaaa gaagaattag
    20941 ccaacctttc attagctgtt gaagaaaata gccctaccta tgtagcaaaa agtaaagctg
    21001 gcaatcttta cacagttact agtgtggatg gattaggtgg tgccggtgcg tacgataagg
    21061 attttcattt tttgaatgcg gtaacagagt ctggcgctcc tttgtgttat gtagcggttg
    21121 atgaagcacg tcaattacta tacggggcga actatcataa aggtgaagta aatgtctacc
    21181 atatattagg agatggcgaa ctgaaagcag cagattcaat attccatcaa gaagcgacag
    21241 gtcctcataa aaaccaagat catgcgcatg tccactatac ggatctgact cctgaccaac
    21301 gattagtcgt atgtgatctt ggtacagatc gtgtgtatac ttatgatgtg tccgaaaacg
    21361 gcaaattgaa tcttgtaact accttcactg cagagccagg aacaggccct cgccatcttg
    21421 tctttcatcc aaatggacaa ttcgcttatt tatttggtga attagacagc acagtccgcg
    21481 tgctttctta taataaagaa acaggtgctt ttgaagaatt acagaaaata tcgaccttgc
    21541 cagaagaatt cgacggtgaa aatggagggg cagctatccg catttcaaat gatggcaagt
    21601 tcctttatgc ttctaaccga ggacataact cgattgctgt attcgcagtt tttgaagatg
    21661 gttcccacat tcaaaacaag caaatcatct caacagaagg ggattttccc cgcgatttcg
    21721 cactagatcc aagcaataat tttgtcgtgt gtgccaatca gaacaccgat aatctgacat
    21781 tatatcgccg tcatcctgaa acaggattac tggaattact gaaaaaagat gtctatgtac
    21841 cagaatgtgt ctgtgtttat tttgatcgtt agtaagaaaa ggagaatgaa atgaatcagc
    21901 aagacgtatt agacagacta cgggaagaac taaatattcc tttctttgat gggaaaatcg
    21961 aagataaaga gtatagcgaa gaggaatatc agaaactcaa agccgattta cagaactact
    22021 ttgaacaata tgtacagaat gtagaaaact aatcagcttt ccatactatc tgaaaagaac
    22081 atcaggacaa gacttttccg tctatcctga tgttcttttc tacaaataaa aaaccgccga
    22141 gatggttaga ctcgacggaa aaggagtatt tactcgattt tgagtaagta caaggttgtt
    22201 gttggttata ggtatgtcat tatcataaag gattttgatc actctatcat aaaggtaata
    22261 ttacatttat attagataac tctagttttt attgttatca aagatttctt ttattttttc
    22321 aacaacaaat tagtcatttt ttggatggca gctgtcaatt ggtctgtcgc ttggtcttgt
    22381 tttgcttcag atgtattgaa tagatcttca tctacccctg attcaagatc gatactttgg
    22441 atcatttctt cacagcctgc tacatatgaa agataagctt tttcaaaatt tttatgaatg
    22501 cccattgctt ttgctggtgg acgcaaagta ctgactttct taagcattgc ccgatatttt
    22561 tttgttcctt cttcaaataa caggatgatc tcttcaagag tcgatttgtc cagttcactt
    22621 gtttttcctt catcaattgc gtttctgatc acttcatatt tcggatgcat tccttctccg
    22681 attgcttctg tttccttgac gatttgatcg atggactgca cataatagcc aatattcggt
    22741 aacatgttcg ttttcctact ttctccattg ttgttattat ttattctact tgtttttatc
    22801 ctcaaatgac aagtacttga aaaaatttaa tggtttctat acagctcgcc attcttattc
    22861 gtgctcaaag aaaccatctg ctaaactata ttgtttccct gcgacaatgt catattggat
    22921 caattgatat tcgtcgtaaa tctcttgttg cgagcgattg aattgcgctt ctttatacca
    22981 ctgtccgttt tgatagtaca gttctcgttc aaacgccgga agttcctgtt ctaatgataa
    23041 aagcagctga taaaagccat ttgttgtctg attcgtctgt tccattagat tcgctgcaaa
    23101 ataaaacgga ctggtgattg catcgtgagt cgtttgcttt tctaattctc ctttactgtc
    23161 gaacataaga aattgtgttt catgcaatgt ttgtttgtca ttttttgctt ggatcgtatc
    23221 tgaatagatc cctggaagat gatcccccca aaaaacaact aaagtccttc tagaaagatt
    23281 cttcaattct tccgtgaact gcttcagtgc cgtgctgcta taggaaatat cttgcagata
    23341 attctctaag tcaagtgtcc cacttccatc tgaagttttt gcaggatagt ctagattatc
    23401 atactttcca tcgtagggca tatgtgtctg catcgtgact aaatgaatga actgaggtgt
    23461 tttttcttcc ttgagaagtg tcattacttc tttgtaagct gactcatcag aaatatatgg
    23521 attattctct atcgtatccg tataggtcat cgtacgctcg ctgatgaact ggtcaaatcc
    23581 taatgtctga taaacatcct ctcttttata catcgaagta ttgtatggat ggatcgctgt
    23641 cgtctggtat gattgtgcgt ttaacgctga aacgatagaa ggaagctgat ccatttttgg
    23701 tacaagcatc gtgtaagggg tggtgagttg cgcattaaat aacgccatag aaaaaccagt
    23761 caatgcttca aattcgatat ttgctgttcc accgccatag ttttgagaaa gcatattgcc
    23821 actatatgtt tgatcagcta cttcataata atctgccaat ggctcaccag atacttctac
    23881 gccgtttaat cgactaggat ctgagaaact ttcactcatc acgaacacga tgttcggcga
    23941 ctcttcctct acagttttat ttttttcatc ggctagcttc tggtattttt cagtgatttc
    24001 tttgatcttt tctttcgaat atccttcagg ttcatccatt ggttctacct tcagattgta
    24061 caaaaaccca ccgataaaac cagtgttata gtagttcatt ttctggctgt aaggtatcca
    24121 tagtgccgtt ttattatatg cttttcgcaa caaattatcg ggattgttga aattactgat
    24181 ataccctagc agtccaattg ccacaagcag tgtcgttaat cggatcaatt ggaatcgcct
    24241 tccttttttc aggcttcgaa acatgtacca gcaaaacaat cctatcacgg ttcctgcggc
    24301 agctaagatc actgtaaaca gcatagtgcc ggtcatatct ttcagcaatc cgatttcagt
    24361 gatcatcttc aaatcgtctg gataaatcgg ttcttgccga taactcattt tcatataatt
    24421 tgcaaaacct aatacaccga tggctacgac atacgtaagg gaacctaaag ggacagatcc
    24481 tgctagtgca atcagaaaaa taagaataat cagcaagacg agacaggcta agaagaattt
    24541 ttccgtatgc caagaaaaag caaatttcaa cgcaaggtct acggatagat cattttgaca
    24601 ccactgcaaa aataaattac taaaaacaac aagaaaaaag atactgatga ttgctgctgt
    24661 tccttttaaa atctttttct gtttggtcga aagtctgctt atatatcttt tcaaatgctt
    24721 gctccttcat ttctatcaat aaaagaatgt tgcttctctt attttagttg tacgaaattc
    24781 gaaagtaaag aacggaaaga agaattaatg aaatccaaat attctctttc tttatggcct
    24841 ttctggtttc tttaataagc ggacctttcg tactccagaa attttttcta gctgttgttt
    24901 cacttgattg agctgttcaa aatcagtact gtctatgtca atcaatatgt agacatgctc
    24961 attcttatgg ttacgcgata tatctgcgat cgctagctcg ttctcattca gcagagaaaa
    25021 tatctctgct aatatattgg ttttcttttg ataaaatata gtgaatcgaa acggcgcttg
    25081 gaaaaacatt cgtgcggatg gataattgac cgcttctcta accgtaccga acaaaagata
    25141 atcttttaag gcttcaactg ccaaacgtcc gctgtctgcc aaagcttcct gagtcgatcc
    25201 ccctagatga ggcaacataa gtatacggtc attttctaag aactcttctt ctggaaaatc
    25261 agtcaagtat ttagccagat gttgtttttc caatgcttgc ataacagcat atttatcaac
    25321 aatttcactt cttcctacat tgataagtac agcatctttt ttcatttttt ctatattcgc
    25381 ctgatcgatc aatccttttg tatcttctgt caacggcagc atgactacga tgtaatccga
    25441 ggtagaaaga actgtttcta aatctgcttg ccgaacataa tccaactggg catcgcggat
    25501 agaataaccc aagacatcca tccctaagct atagcaactt agcgctactt ttgtgcctat
    25561 cgctccaaga ccaagaagac cgatggtttt gccttgcaat tctcgtccca cataagcact
    25621 tcttttgttt tctgcctgtt ctaaaatatt aggacctgtt agtgtttgta ccatacgact
    25681 tgcttcgatt atcggacggg aagataagag caaacagcac aaaacaagct cttttactgc
    25741 attagcattt acacctggtg tattcatgac gatcgtcccg ttttcagaag ctttttcaac
    25801 gttgatcgtg ttcaccccaa caccagctct tgaaattgct agcaaatctg gtgtaagcca
    25861 ttcatctttc actttcgtac tacgaataac tattccttcg gctggcaaat catctattat
    25921 tttgaaatat tccccttgta acttttctat ctcttgttct ggaatagcat caatcaaatg
    25981 aacgtgatac ataaaacccc ctccttacta acaagtatct cgaaatttct gcaattagac
    26041 aactgtttac catttgactt cctagaagca aaaagagcag ttagagcaga gtaggctgag
    26101 tgataaaaat aaggctatga caagttactg ccataagcct tattttcgag agcaaaatat
    26161 tgagggtgag atatcttgat aaatggtgtt ccgttagctg acattgataa taagactaaa
    26221 tttcaaaaaa gttgaaaagc aaatttcgtc aatctcttct tatttcttaa aactaagtgg
    26281 ctttttcaca acctcttttt atctaataac cactgtttcc aactcaacta attttgccca
    26341 cgtttcaatt tgatctgttg ttagatttag cgagacaacg gtatgatgac cgccacctgc
    26401 ctgaatccat gaatggacac cttcatggaa attcggttta gttttccata acacacgtgc
    26461 aacaggtaaa ttaggtgctt cagtcgttgg ttcaaaggct tctacttcat tgatcagcag
    26521 tttataatgc gtaccgaaat ctgccatcga tacgactacc ccttctcctg ctttcccatc
    26581 aaatacaaga cgcgccggat cttctctatc tcccattgat aaaggagaaa caacgattct
    26641 tggtttcgtc gcagcaagcg tcggatctac ttccatcata tgggattcca agattgcttc
    26701 ttggccacta gctagctcgt aagtataatc ttccatgaat cctgtatctt tccctcgagc
    26761 catgattttc agcaaccgat caatcgctgc agttttccag tcgccttccc cagcaaaacc
    26821 gtatccttct gccatcaaac gttgtacagc tagtccaggt agttgtttca ttccatacag
    26881 gtcttcaaaa ttagtcgtaa aagcgttata gcctccttct tctaagaaac ggcgaatacc
    26941 gatttcctgc tgagcttgta cttttacatg ttcctcccat gtcttttctt cataatcacc
    27001 atagtcgaag gtatacaatt ccttgtactc ttcaaataat tgatcgactt cttcgtctga
    27061 tacgcgatcg attacttgta caagatctcc gataccaaaa taatcaacag tccaaccaaa
    27121 ttgaatctgt gcttccactt tgtctccttc tgtgacaccc acgtttctca tgttgtcacc
    27181 aaaacgagcc acttttattc caaaattata tgggatttta gattatcttt ttagaagttc
    27241 ttgaatgtcg gtatagcccg tgtttccggg cttttccggc atttttgata ttgttagata
    27301 cttacaaatg ttcttattac ctctcaccat ttccccctca aaagtagtaa atggagtagt
    27361 aaaaccggcc ttgtgtcagg ctgccagccg ttccatttct gcccttgcgg aatcgaatgt
    27421 ggcgtgtgca taatagttca gcgtcatggt gatattggaa tgtcccataa tgtactgcaa
    27481 ggctttgggg ttcattcccg cattggctaa ccgggtgcag aatgtatgac gcatagcatg
    27541 gggcgtcgtc gttttcggca acgcttcttc atggctcttg ttgtacttct tcacaagcct
    27601 gccaaacatc ccgccataat ctaccgccgt catgggatag ccgttctgtt tgagaaacag
    27661 gaaattggca tacccgtcaa taatgaacgg ctttgcacct ttgcggtttt ttatcactcg
    27721 ctggaacgcc tgatacactt cctcattcat ggggattttt ctgacgccgc tttgggtctt
    27781 gggttcgtca atatagtaac cgacgccggt atttctcaaa agctggtggc tcacgatgat
    27841 tacccggttt tcaaaatcca aatctttgtc cgtcagtccg cacagttccg aaatgcgaag
    27901 ccctgtcccc agcagaataa cgattgcgtc ataatgcttt tggtaaacct tatcaccttg
    27961 aataaaggac agaaaacttt cttcctgtgc tggtgtaaga ggcacctttg gttccgtatc
    28021 gtcgtccaga acgtcactaa gctggaagtc aaacgggttt tttcggatgc aatcgtcctg
    28081 tatggcggtg taaaaagccg ctttcaggga acgcttgtcg ttattgatgg tcttataaga
    28141 aaggcccttt tctttcatcc gaagcgccca ttcctttgcg tcggacagct tcacactgtc
    28201 aatcgggcag ctccccagcc gatcttgttc cagaatacgc atcagccgtt cccggcccag
    28261 tttggtgttg tgcttcacat tgccccggtg cctgatctgc ttggcgtaga gctggcagac
    28321 ggtcattttc ttgccgatgg tgtctatccc gtcgtcaagg tctttctgga tttctttctc
    28381 cttttcccgg agtgaaatat cctcccgttt acctgccggg gtcttatccg taggcactaa
    28441 cttccatgag taaacaaact gcggttttcc aaaggtatca acatatttgt aagcatatcg
    28501 tccgtctttt ctctggctct ctccagaccg caaaacgcga tttttgctgt ctcgtctttt
    28561 ttctgacatc tcgtcatgct cctttccatg acggaaagag ccgcatatat gcttataaat
    28621 tattataaca tatctgcggc cctttttcac tattagattg tgtccaaagt gtcaattatt
    28681 ttctcaaact gcttgcgttt gatctggatg cggttgccat tcataatgac ccagccagag
    28741 gccggatttt cctcggccag cttacgcaat ttgttttctc cgatacggaa atatttagac
    28801 gcttcctcaa tcgtcagcgt gtatttttcc caaataggca catcatggtt cataatgcag
    28861 ccccctttca caaattcaaa ggtttgtgtg atttaggggc atagacggac ggctgctggc
    28921 acagctccac gggactttca cccccgcgtg gttctcacgc ggccctaccc attgcctgcg
    28981 acgcttttaa cgctcggact gtggctataa gggagtatca tagtcctgcc tgtacgtcgt
    29041 cgcccgcaag ccgccacgct cacattgcgg cgtggtgttc ctcgctccgc ttttcccgta
    29101 gggaaaagta tcatggcgca ccagccgtcc ggctcggcac agacagaatg tgtccgtatg
    29161 ccctatgatg cgccgccgtt atcttgcggg catatttatc aaggtgcgat caggccaccg
    29221 ggaaaacacc gaaacgggga aagggtaagc cgtttcatgc tgccggggcc ggttcgtcag
    29281 ttcgtgacga tagcgtggat gagcttgatt tccagacggc gcttcatggc ctcgtccaga
    29341 cacacatgcg gatagccgtt ttcgtcatag agcgtccggg tacacagctt gttcatgtaa
    29401 ccgctgtaat actgcaaaac gcgctctacg gctccggcat ccccagcgcg ggcggcctcg
    29461 atcaccgaaa ggggcaaaag ctcaatgccc ttgtagttcg ggttcttcat ccgcgtctaa
    29521 cctcccttcg gcatcaacgc ctttagctgt ttccgcagct ccgataaggt atttgtcctg
    29581 tgccgctgaa cggcactccg ggacattccc acaaggccgc cgatctcacc atctgccata
    29641 tccagaacac agtgcaggat taaaatactc tgctccatgc tgggcagcgc ggcaaaggct
    29701 tcggcaacaa gctcattgtt gatatgtagg tcatagccat gcgacgaaaa cgtaaagctg
    29761 tcgctggggt agtgatctac tgtacagagc ttgtccaaat ctgcctgtga caaagagctt
    29821 agtgacactt cacggtcacg gcggcgcttc atttcagcca agtagctttt ggcctcgtta
    29881 cgcagtaccg tcttgcaaaa agcatcgaac atgcaccgcg cttcatagtc gcgggggata
    29941 gcatccatct tctcaccccc tttctgtggg ggacttaggt ggttctctcc ctttccgcta
    30001 acaagacttt gacaaggccg ccagctaccc gctaaatacc tcctttttga aaatttctca
    30061 aaaaattttt ttggggacag ccgggccgca aaagacgaca aaaatcgccc ggcaggtcgc
    30121 aaacctaccg ggcgagaaaa tgctttgcta tgctgctgat ttacatggta tagtacatac
    30181 tcataaccgg aatagccctg tg
//
LOCUS       DADGKS010000028        29723 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.028, whole genome shotgun sequence.
ACCESSION   DADGKS010000028 DADGKS010000000
VERSION     DADGKS010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29723
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.028"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(20..964)
                     /locus_tag="JXV47_001391"
     CDS             complement(20..964)
                     /locus_tag="JXV47_001391"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAX1487443.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(1260..2204)
                     /locus_tag="JXV47_001392"
     CDS             complement(1260..2204)
                     /locus_tag="JXV47_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1487444.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            2425..3639
                     /locus_tag="JXV47_001393"
     CDS             2425..3639
                     /locus_tag="JXV47_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAX1487445.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            3661..5676
                     /locus_tag="JXV47_001394"
     CDS             3661..5676
                     /locus_tag="JXV47_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HAX1487446.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(5759..7132)
                     /locus_tag="JXV47_001395"
     CDS             complement(5759..7132)
                     /locus_tag="JXV47_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAX1487447.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(7158..7442)
                     /locus_tag="JXV47_001396"
     CDS             complement(7158..7442)
                     /locus_tag="JXV47_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAX1487448.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(7444..9459)
                     /locus_tag="JXV47_001397"
     CDS             complement(7444..9459)
                     /locus_tag="JXV47_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAX1487449.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(9638..9943)
                     /locus_tag="JXV47_001398"
     CDS             complement(9638..9943)
                     /locus_tag="JXV47_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HAX1487450.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(10032..11063)
                     /locus_tag="JXV47_001399"
     CDS             complement(10032..11063)
                     /locus_tag="JXV47_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HAX1487451.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            11270..12145
                     /locus_tag="JXV47_001400"
     CDS             11270..12145
                     /locus_tag="JXV47_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAX1487452.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(12297..13139)
                     /locus_tag="JXV47_001401"
     CDS             complement(12297..13139)
                     /locus_tag="JXV47_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAX1487453.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(13231..15108)
                     /locus_tag="JXV47_001402"
     CDS             complement(13231..15108)
                     /locus_tag="JXV47_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAX1487454.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(15105..16526)
                     /locus_tag="JXV47_001403"
     CDS             complement(15105..16526)
                     /locus_tag="JXV47_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAX1487455.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(16529..19918)
                     /locus_tag="JXV47_001404"
     CDS             complement(16529..19918)
                     /locus_tag="JXV47_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAX1487456.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            20175..21566
                     /locus_tag="JXV47_001405"
     CDS             20175..21566
                     /locus_tag="JXV47_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAX1487457.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(21639..22286)
                     /locus_tag="JXV47_001406"
     CDS             complement(21639..22286)
                     /locus_tag="JXV47_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAX1487458.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(22294..22980)
                     /locus_tag="JXV47_001407"
     CDS             complement(22294..22980)
                     /locus_tag="JXV47_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1487459.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(22986..24059)
                     /locus_tag="JXV47_001408"
     CDS             complement(22986..24059)
                     /locus_tag="JXV47_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAX1487460.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            24281..24955
                     /locus_tag="JXV47_001409"
     CDS             24281..24955
                     /locus_tag="JXV47_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1487461.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            24960..26300
                     /locus_tag="JXV47_001410"
     CDS             24960..26300
                     /locus_tag="JXV47_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAX1487462.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(26449..27435)
                     /locus_tag="JXV47_001411"
     CDS             complement(26449..27435)
                     /locus_tag="JXV47_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HAX1487463.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            28159..29190
                     /locus_tag="JXV47_001412"
     CDS             28159..29190
                     /locus_tag="JXV47_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAX1487464.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            29299..>29723
                     /locus_tag="JXV47_001413"
     CDS             29299..>29723
                     /locus_tag="JXV47_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HAX1487465.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIP"
BASE COUNT         8801 a         5580 c         5354 g         9988 t
ORIGIN      
        1 agttcatatt cattgtttct tataatacag tgttcaatac ttctcttaaa gcacttgttg
       61 atttgctgaa cattgctttt tcttcttcgt tgattgataa ttcaacaact tcacgaacac
      121 cattttcgtc aacgattgat ggcacacctg taaagatatc tttttcgtcg tattcaccag
      181 ttaaataagc agatacaggc aatacagctt gttcgttatt caagatagct tttacgatac
      241 gtgcagtact cataccaata ccatagtaag ttgctttttt acgatcaatg atctcataag
      301 cagcattacg gactttatca gcaatcacat ctaattcatc ttgggcaata cgatggtctt
      361 tttctacaat ttcaaacact ggtttaccac cgacagttgt atgtgaccat gcagcaactt
      421 ctgaatcacc atgttcacct aagatatagc cgtggacgct gcgtgggtca acttttaatt
      481 tcaatgcgat ttctttacgg aaacgagttg tatccaatgt tgttccagta ccgataacac
      541 gtgatgttgg cagaccagat tcgttccaag cgatatatgt caaaatatct actgggtttg
      601 aagcaacaac gataataccg tcgaatcctg atcccatgat ttcttttacg atttggcgca
      661 tgattgacgc atttgtttta actaaatcta aacgagattg accaggtttt tggttgatac
      721 cagctgtgat aacaacgata tcagcatctt tacattcttc atagccacct gaccatacag
      781 ccacattttc atcgccccaa gccataccat ctaaaaggtc caatgcttcc ccttctgctt
      841 tttcttgatt cacatcgatc aatactaatt cattagagat tccttggttg atcattgcat
      901 aagcgatact tgttccaaca aaacctgtac cgacgattac tactttacga cttgtttttt
      961 tcatgaataa acagctcctt ttcataacta tttgttactt tcatgaaaag tatagtcttg
     1021 tttattcatt ttatcaacat gttaattata atagttgtta ttataatttt tgatggaaac
     1081 gaattcctga atacgcataa cagataaatg acaaatgttt acacctatat cccctgataa
     1141 tacaaccaaa agtttagaac tgaaaataaa tccaaaaaaa ttcgctgcaa cgatataata
     1201 agacagcaat cgcacctaaa acaattttcc ttcatatgct ttagtgaaag attttcttct
     1261 taatgtttat ttctccattc attgggagta catgttgaat acttcttgaa taatttgaat
     1321 aaagaagtcg tttgtttata tccgatacga ttagcgattt cttccaacga aaaactcgtt
     1381 tcttgaatca gttccaacgc aaagtcgaat tttttcttta gaaccagttc ttgaaaggaa
     1441 gcatcaaaat acattttcaa tttattacta agatagaccg gattgtagcc aaaatgagct
     1501 gctgtttctt ttaacgtaca agaagtaaaa tgcttatcga tataatctaa tactctaagc
     1561 atctcatttt ctgcgcatcc atctgctgat gaaaagcttt gttgttctaa taaatgagtc
     1621 aattcgatca gtaatagtga tgtatagaga tttaacgaac ggatcttatg actgtatgta
     1681 tcaaaataaa tcaacagcat attttcaatc aaatgcgtca aacgacttgt ttttccgccg
     1741 cgaaaatgaa tgaattgtgt atgttcccct ttttcttttg atgcatttat caaaaaagaa
     1801 gaaagtagat tatttgtgct tgccaaatga ttcaatatct ctgtagataa ggtttcttct
     1861 tttaataaga tgttgattaa aatatcctct tgccctgtgt attcgattct ttgagtagct
     1921 tctttatcaa tgatcaccac gtcactttct tccatctcta tcctttctcc attaataatt
     1981 tgtaaacatg taccgctata catataattg atttcaacaa aatcatgtgt atgctcggga
     2041 acttccgcat atcgacggtg tttactgata tgaatatttc cctgttgaaa tagatcccct
     2101 cggtggattt ttggcggtgt ctgaagatgg taagctaagt ttaaatcatt gatattcatt
     2161 ccttgttcac gctgcagagt ttcgattgat tcttcgttac gcaaaaaaaa tgtctaattc
     2221 agctagttcc aattgactcc ctcctttttg taagcggttt ctttcgctta ttagttcacg
     2281 ctgtactgct attatatgca aagctatttt tggtttcata aagactttct atggttggga
     2341 catgaacttc ctgtgattcc gctattgaga gaataaccac ttcatactat atttttgata
     2401 agcgcttaca aaaatgaaag gaacatgctt atgaataaaa agatgatgaa attttctctg
     2461 ctgtcagtct ctcttatttt gacttctgct ggtgcagtca cgtctgcaat tcccagtatg
     2521 tcagctactt atgccacgcg ttctttatct gctgttgaat tattaacgac tgctccctct
     2581 tttatggtca ctatttttgt tttgattagt agttttattg ctaggaaaat cggacaaaaa
     2641 caaactgtga tcatcggatt agtgattgca tcgatttgtg gtatcctccc cctcttctca
     2701 caaagttaca gtattgtctt agcttcaaga gctggactag gtattggctt tggattgatc
     2761 aattctttgg cagtcagcat gattgctgcc ttttatcacg gagatgaacg agcctctatg
     2821 attggttttc aaagtgcatt tcaaggattt ggtgcagctt taatgacatt tgttgcagga
     2881 cagctagtac agttcggttg gcaatatacc tttttagtct acgccatcag cttacctatt
     2941 cttgtcttgt ttgttttgtt tgttcctaca cctgaaacaa ctgaacttca atcgcatggc
     3001 acagccccaa caagacaagt aatcaaaacg aatcctaaaa tgattagtta tggtattttt
     3061 ctcttgctgg tcatcgtggt atataatgct gtatcgatta aattagccac agtcctgacg
     3121 acttattctc taggaaacga aactaatgca gcgaatatct taacaatcat gcaattggca
     3181 agtatggctg ccggagtttg ttttggctgg cttcagacaa aagcacatcg ctatatgctt
     3241 acactttctt tactactgat gggaatcggc tttgtattga ttgccactgt gataaacctg
     3301 tatgtgattg ggtttggtgc gatcctaaca ggaatttctt tttcgttatt cattccttac
     3361 ttattcaacc aagtaagtat ccaagcgccc aagtacgcgg agagtttcaa tacttcaatc
     3421 ttattggttg gcgctaattt aggtactttc attgcaccat atggtttgct ctttctctct
     3481 tttgcttctc ttgggagtaa aacacttgct gttttcgtca atggcagtat cttgctgttg
     3541 attagcgcgc ttattagcct tctagtagta cacaggacga atagaaagac agtgataaga
     3601 gtagatgaag aaataaaaga acaattgaca acaaaataaa tttgatggag gtcgtgtaaa
     3661 atgacaaatg aaaaacataa agatagatgg ctttggtatc ctggagactt tgagatccgc
     3721 catggactgc tacaaaattt ccaacgggaa gaacgaggtt ttgactggcc agcgtactgg
     3781 tacatggatg attgccatcg gaacgtcaag tttaagagat attactttct tgatcaacct
     3841 tccatgttta aagtgacgat ccaaggagtt gggtatgtag aaattaatgg acaaaaacat
     3901 ccatgtggaa aatggctgac ttgtccagct ggtaaagcaa aaattcgtat ctttgtagga
     3961 catacatcag ggctaccagc gatgtttatc gagggagacg aagtaaaatc agatattggc
     4021 tggacagcaa gtaattttat tgaagaatat ccagctggct ggagtccgct ttatgtcgat
     4081 atcgcaaaag atccaaatca aatctattat caaaaagaat gcgtccatcc agtcactgaa
     4141 acggagattg gcggaggaat cttattcgat tttgggcgag cagtgaatgg ctgtgtagaa
     4201 ctaatatctc tggatgacca tatcgaatct atcactctat gttatggaga gtccgatgta
     4261 gaagctatgg atatcgatta ttgctactat aagcaaatag gaatgacaag aaaaatgaaa
     4321 gctcgtaaac gcgcttttcg ctatttgttt ataccagagg tttctactgg aatggttcaa
     4381 cttcaagttt ttcatgaatt tttatctctt tcgaaacaag ctgctttttc aagcgattct
     4441 tctttactga atcagatctg gtcagtatca gaagaagcct tcaagttatg tagtgatttg
     4501 ttttttatcg acggtatcaa acgagatcgc tggatttggt ctggagatgc gtatcaatca
     4561 ttcatgatca atcaatatct tttttttgac gaggaaatca ataaacgaac gatattagca
     4621 ttaagaggac aaaatgaaat caagcagcat atgaatacta tcgttgacta ttcgatcttg
     4681 tggttgattg gtatcgaaaa ccactatatg atgacgaaag actatgaatt tttacgcatc
     4741 gtctacccta agatgcaatc attaatgaga tacttgatgg agcaaacgaa tgaattaggg
     4801 tttatttatg ggagagcaaa agattggata tttattgatt ggtctgaaat ggataaagaa
     4861 ggaacgcttg ctgcagaaca agtcttatta ctgaaagcct atcattccat gatcacttgc
     4921 ggagatatct tagctgaaac atatggagag aacgaaaatt atcatactca tctctatcaa
     4981 gaaaaatatc aactattgaa acaaaaccta tttgactact tttgggatga agaacttggc
     5041 gcttttatcg attgctatga atctgggaga agaaatgtga cgcgtcatgc gaatattttc
     5101 gctgttttat tcgattttgc taacaaagac caacagcaat cgatcttaaa gaatgtctta
     5161 ttgaatgaca ctatcacaca gattactact ccatatttca aattctatga acaagatgct
     5221 ttatgcaaac tcggacagac gaatatcgtc taccaaacga ttcttgatta ttggggaggg
     5281 atgttatctc atgatgcggt aactttctgg gaagaatacg accctactca aacaggaaat
     5341 gaaaagtaca gtatgtatgg agatccttat ggaaaaagct tatgccatgc atggggagca
     5401 agcccaatct atcttttagg acgctatttt atcggtttgt atccaacaaa gccaggttat
     5461 gaagaattta tgatacaacc taatctagat tcatttgaaa cactgaattg tacgctacct
     5521 atcaaagatg gaaagatttc gcttgaaaaa acaaaagata agatcgtgat tacttctgat
     5581 agaacaggcg gaacagtgaa aatgaatggt aaaagttatc ctcttctagc aaaacagcca
     5641 cttgtcttaa caagctattc aaaaataaat gcataaaaca aaaaactgct tgcgacatat
     5701 cagaagactt taaatcttct tctgatattg tccaagcaat ttttattttg aagtttgctt
     5761 aattctgttc tttagaaaca atgtttgttc tttttccggc aaaaagaaag ctagataata
     5821 cgacaagtaa aaagaaagcg atgattccaa ctgtcaaggc tatttgaccg tattctccta
     5881 gtttcccaag tacaagtcct ggtactagat aatcagtatc ggcaaatgta gaagaagcga
     5941 ttttaagatc tcctaatact ggaaggataa ataatggcag ccaactaatc aataagctat
     6001 tgaaagcaga acctaatacc gcccctcttc taccgccagt cgagttgccg aagacaccag
     6061 aagcagctcc gcagaagaaa tgtcctacta ccccaggaat gataactgta gtttgcaagc
     6121 ctatcatagc aaacatggat agtgttccta caaagaagct aacaaaaaag ccaattaata
     6181 cagcattagg tgcatatgga aaaacgatag gaacatctaa tgctggttta gaatcgggta
     6241 cgagtttttt agcaatccct tggaatgctg gaacgatttc tgccaacacc attcgaaccc
     6301 cttgaaggac gataacaaac ccagctgtga atgttccagc ttggatcagt gcaaagatta
     6361 cagcgttgtc tccattgctt agttctcttt caacaaatcc aggaccagct aacaaagcaa
     6421 gtgcgacata tacgatcgac atcaagagca tgatcgatac agtagaatct cgcaaaaagc
     6481 tgaaactttt aggaatcttt atgtcctctg tagaacggtc tttgtttcca aaaaactttc
     6541 cgatccatcc actagaagca taaccgatat ttccggtatg ccctaacgca acttgattgt
     6601 ttccagtgat gttcttcata aacggttgac aaagagcagg cgtaatagtt aatagtgttc
     6661 cttcgaagac cccgcctaat aagatcatcc acaaatttgc agtaaacccc gcgcttacta
     6721 aaatgactgc tgttagacaa gaaacataaa gcattgcttg acctgtaaga aaaatgaatt
     6781 tatatcttgt gaatctagca agtaaaatat tcacgatcat ccctactagc atgatcaaag
     6841 cagtaggtgt accgtattgt tgcaaagcaa tcgccactac tgcttcattg ctaggaacta
     6901 ctccttgagt atgcagagct gtttggaaca tcgaagcaaa aggggttagt gaattactga
     6961 ttaaaccagc accgccgatc agtactagga atccgacaaa tgttttgata gttccttgga
     7021 tcacttctga aaatttcttc ttctgaagaa cgagaccaag cagtgcaatc aaagaaacga
     7081 ggatggaggg ctgactgacg attgacacaa acaaattcaa caatttatcc attgatagtt
     7141 cctcccttga atcattttta ttcttttgac aagatcttcg ttactttttc ttttacttct
     7201 tcgctgtcaa tgatcgattg caaaggtacg agcttttcat caggtataga agttagcgta
     7261 tctttcaaag aatgctcaat gaagaaataa tcagccatat cgctagatac acttccaaca
     7321 tccgtatgac ttacttcaaa ctcgtccaca tctgctccaa gatctgcaag tgcttgtttg
     7381 atgttcatct ctaccataaa acttgttcct aatccacttt gacatactgc aaaaattttc
     7441 atatcattcg tctccttttc ttatgatcgc taatatttct tcttttgttg atgcgtgtaa
     7501 taaatcttga agattttgtt tattagaaag tagctttgtt aaatttgcca aagcccgaag
     7561 atgtgcctca ttatcgatag cagctaaaca gatgaacaaa ctaatgggat gggctggatt
     7621 atcaagcaga tccacaggtt gttgaagttt cagcaaagac atccctactt cgtttacgcc
     7681 atcttctgga cgagcatgag gtaatgcgat gtgatcgcca atatggataa acgcaccata
     7741 ctgctccacg cgctcgatca tagctttgat ataactttct tctattttat tttctgataa
     7801 tagcggctgt gcggcaaatg tgattgcttc ttgccagttt tttggttgat ccgataattg
     7861 gatcatttct tctgttaata attcagatag cataggacgt tgatcctcct tcttttctaa
     7921 aagtttgttc attttacgat ttaatacttg atagagcttt tcttcgtcta cgccttcttt
     7981 taattcgata taaggcagta gcgccgacaa caattcttgg gcagaaggca ttgaaaatcc
     8041 tggtatcagc caatctcttt gtacttgatt gatcagctga tttttttcca agtcagtcat
     8101 gattggatgc agaacataga gagacttttt cttatcagta agtgtgagag gtacagtaga
     8161 aaaaataata tcgtaagaag tttcgtcaac ctcgtgtaag cggtcagctg aattagtctc
     8221 tgtaaaaaag atcatcggga ataattgctg aagttcactt tttaagatca atgaagagct
     8281 aatgccactt ggacagacga tcacggctct tatttttcta tttctttctt ctgcgtccgc
     8341 ttttctgatc tctccgccaa atagtatagt gaaaaaacca atctcttctt cagggatgct
     8401 cttccctatt cgtctttcta acggaagtaa tgcttttctt gtcatttcgt agatggaagc
     8461 atattgatgc ttaatttgat cgatcatcac attaggtaaa taaaaagaat aggaaatacg
     8521 aaaataggca gggaccaagt gataaaagac attcatcaat aattcacgaa acgaagcaaa
     8581 ttctacggcc atcaggaatt ccatgcgatg gatgacttct gaagaacatt ccagcaaaaa
     8641 atcaagtgca ggctcctgga catctccttc aacgatcgat gctaagcaaa gagagaaaaa
     8701 tataatctcc gaattttgat gttcggaata gccaaggcca gtcaatactt gtcgactaat
     8761 gtcagtgact gcaagagaag ccaacagttc agcatctttt accagttcca tggatgtttt
     8821 tccaattcga atggttgtca aactcaaata ataagctaat tcatccattc gatttggtgc
     8881 gaatcgaaga tctgatagtg aaatcgtttt atctagcaaa tctctaactt tggcgtaata
     8941 atcaatggaa agggttgcgg ttaaatacgt gagcccaaat cttccagcaa gtgactgcat
     9001 caaacgagca gtgcgatttt ttgcttctct tcttaatatt gcttctgacc ctagcagcct
     9061 aaaaccagtt ttcctagtat acgacagctg acaatcttcc acttctaatt catttcttat
     9121 ctttttgata tctgacagga ctgtcccttt agaaacctga agaaaatctt gaaaatgaaa
     9181 aacagaaaca gacgttgcag tcgaataaac catcaaataa agaagatctc ttcgctcttg
     9241 ttcggtatac acagcttcaa atcgagtaat atccaaaaat ttttctgccc agtcgattgc
     9301 tcggaatttc tttatacgga tacgggtatc atccacatat tcggcaaaag gagttaattg
     9361 tttgatcgcc tcgcttgtat ttacttcgat gatctctgct gctttttcta gactgatttc
     9421 tcttggtgtt ttcaggagat aactaatttt gtagttcaca gcgctgttca cctcctactt
     9481 atattctagt atggtagcgc ttttaaatcg aggggtgttt ggtacaactt acagttggat
     9541 tttttttacg actgtaccga acgatttcta tcgaatggat acagaaaaaa agcaggtgac
     9601 caaatgtctc ctgcttttat gaattgattt cgtccgatca atgatgatca tgtttatttt
     9661 ttgaggtcag ttcttcaaat ttttctttga catcttcaac cgctttttcg atatcttttt
     9721 caaagtgatt gggctcatta ggctttgttt cctcttctac agaatttgaa ccagataaag
     9781 ctgtttcttt attttctgtt tcaccagagt ttgtgccagc taatgattct tctttgtctt
     9841 ctgtttcacc agaattagtt cctgctaaag ccacttcttc ttctgtttta ggggccattg
     9901 aacctcttaa tcgtttgtgt ttttcaccgt cataatttgt catgttggtt cctcctagta
     9961 gttctatact ttttcatcgt acaataagac agtttatgcg tcaaaaaaca aacccgattc
    10021 ttacaaatat gtcatatttt tccttctgat tcttgaatgc ttttgattcc ttcttccaaa
    10081 attttcattt gtaagattgt ttcttcatct ttgatgactt tttctgcgcc attaactaat
    10141 gtctcgtaaa tcccttcgta gacacggctg taatcaccaa cctcggaaat tactttttct
    10201 tcatgataac tcccttgttc atctatatag gtcaatacac cataatgttc gggcaaatcg
    10261 ataccaaagt cttcatgatc aggcatgtaa aacattttca gatgttcttc ttgtcgatct
    10321 tttgtttgtt tcacgaacat cccttttttt ccgtaaacga cgaaacttgg acgttctttg
    10381 atgcggaaat aactggattt tatcgaaatt ttcatatttc catagaaaaa atccagatcg
    10441 aagtaatcat tcattcgtcc tttccctaaa agttgacgta catcatagct gatatcatct
    10501 ggttcgccga aataagaaag aacttgatct actgtatgac aagcatgtcc atataaatag
    10561 ctgttcgcag tagaaaattc atgcgtattt tctggtactt ccggtctgaa ataatcataa
    10621 tgcatttcta cttctaaaat atcccctaat tttccgcttt cgattacttt ttggactgtc
    10681 aagaagtcag aatcgaaccg tctgttttgg taacattgga taaatagacc tttttctttt
    10741 gctaatgcaa ataactcttc tgcttccttt gacgtttctg caaaaggttt ctctactagt
    10801 acattcttac catgttcgag tgccattttt ccatattcat aatgaaattg actaggtgta
    10861 gtgatgacaa ctaattggat ctcaggatca tcccaaagat cagacagctg atcagtatat
    10921 tcgatgtctt cgaatgtttt ccacactggt tcagatgggg aaaaaatttt tttgatattg
    10981 attttgttcg taagttttct tgaaaaaggc aaatgatagc gatttgtact ctttccattg
    11041 ccaagataag cgattgtaag catgagtggt gcctcctttt attgatgttt tcagtatatc
    11101 ctagaaaagc gcagaaagta tttataatag ctattctggt aaaaaagttc agaaaaacac
    11161 ttgttatcat tcggtttggt gaaattaatg ttcaaagtaa ggataaaaat caaaaagata
    11221 gtagcggaac caagtgttta tcagtaagat agaatttgga ggtcagatca tgcttattga
    11281 agaaaaacta acaaaacaag agttgtttac cacgacagag aaacggattg tcgattacat
    11341 ccgtaggaat atcgaagctg cagtctacat gacgattgaa gaattagcaa aagctacgta
    11401 tacttcccat tcagctatca ttcgtttatg caaaaaaatg ggattcagcg gatttaaaga
    11461 attccgtttc gagctggggc gggaagttca tcaattgatt gctcagttca atcaaacgat
    11521 tgatcctaat tttccttttt caagtgaaga tagcactcag caaattgcaa agaaaatggc
    11581 ggatttatcg atccagtcaa taaaaaaagc acaattgcag attgaacatg aagatttaga
    11641 tcaaatcggt aaagtattga acaaggcaca gcgaatcttt ctttttgcaa aaggtgattc
    11701 tcaaatcacg gcaaggaaat tccagaataa aatggtcaag ttgaataagt ttttgatcat
    11761 ggctgaagaa tacagtgatt cttcttggaa tgcagccaat ttgactagcg aggattgcgc
    11821 catttttatt agctacagcg gtcgcatcca tcattatgaa cgaataatga cctatttgaa
    11881 gcatgtagag gcccctacct tgctgattac cggaaatcag cattcagaaa tggccaaaca
    11941 ggctgatatg tgtcttgtta tatcgcagga ggaatatgat tttgctaaag tagcgacttt
    12001 ctcctctcaa attgccttcg attacgtatt aaatacgtta ttctcagtga tatattctca
    12061 aaattttgaa gagaatatcc gcaacttgaa aaacaaacaa gaattgatgc aaaaaggcct
    12121 tcttaaagaa tatcggaaaa cttaagaaaa gatcctcatt tagtaataag aaagatagtg
    12181 tttgataggc tctctttgat atcatcataa aaacaggctg aagttttctt tttcaaacct
    12241 cagcctgttt gtttacggaa cgattcgaat agatatatta tagaaatgag gaatagctaa
    12301 cttctgtttc ttattttgaa cgattgacga aaaagatata taagaaggag gaaaatcagt
    12361 atacatgcag ctaacaatcc atacaggaaa aatcgtttgt tctcggatac tttctgtact
    12421 tctttttgaa cttcttttgc atgataagga acccggtgcc ctctgacaag taagcgatga
    12481 ctgttgacca tataaggtgt acaagttagg agtgtcacga aatcctgccc tttttcgatt
    12541 ctcagatctt ttgtatcagt cggttctacc gtcttgatct gatcgacttg ataagcgagt
    12601 gtccgtccat tgatttcgat atagaaagaa tcacctaaag tcagtttcgg taagtctgtg
    12661 aacaactttg cttgaggcag tcctcgatgg ctggaaataa cggcatgtgt attttctccc
    12721 cccgtaggat aagacgttcc ttccaataat gaggcacctt tttctagcag cacagtattc
    12781 gtttcatcaa aaattggcaa atggacattg atctcaggga tcgtcaaaat accgatcgta
    12841 tgtttctcaa aataggttct atcctttttc gcaggttctt ttttcttagt aaagggatct
    12901 gcacctggat ttccaccttc ttttgctaat tgctggtttt tctttgtcat gttttcttgg
    12961 attttagcca tgacttcttc attttctttg accgcttgtt gctgataatg agagatgatc
    13021 tgctgatcca gataattatt cagcgcgtcg ctaacaaatg gataagctag tatccctatt
    13081 cctgagagaa gcaagaaaag catcagcaga tctagaagtt tccttttctt tggtttcatt
    13141 tgtgttctcc ttgtgatgac tgtttgataa taaaagaaaa aggagcattt gcgtaatccg
    13201 ctgctccttt ttccaattct tgcaaaaaga ctaaatctga ctgtgcttgc gtctagcaaa
    13261 gtacagtcca gcaatcagta gaaggactac tcctgcaccg atatacacat agattccctt
    13321 accgcctgtt gaaggaagtg tacctttgtg tttatttggt attttttcag gagaaatcaa
    13381 ctgtcctgct gttacataag attgttcatc gatagtaaat gctacacggt ttgttaatgg
    13441 aacatatttt tctggcgctt tcgtttcttc cagatagtac gtgccatatt ttagacctgt
    13501 cacatcgatt aaaccgttac ttgtggttgt aaaaaccgtt gctgattctt tcgccgatac
    13561 ccagctgacg gcttttgtgg atgggtcgat cgataaatat ttcgctgtgt cactatcttg
    13621 atcacgaacg acgaattctg ctccagcaag tgtttggtct gatgtaacgt caccatctac
    13681 tttaacaaat cgtttgcccc cagtaacgac atcgactgac ggtggtgttt gatcatttgt
    13741 atgcccgtta tcgacatttg cttggttaga aaatcctttg gttggatctg ctttttcgtt
    13801 caaatgcata tagtaaacga atttcaatgt accgccagga gttaatgaag gaatataatt
    13861 cggatcaact gaaaccgtga atccgtctgt ttgctcagtg acagaataat ttactgggtc
    13921 gatttcttta tttccatcat ataaggcata agcatacgtt cctgaagaat cattatcaaa
    13981 tgttaaagca gcgtcatgag tatcgataag tttgaatgtt gtgtacttgt tttgcgttcc
    14041 ttctttatca gcgataccta atgggatatt gacagaaatc tcatattgaa ttttttcacc
    14101 gattgcgaca tcttttccat tcaattgagg tgttgtttta tcaactttag acgtatcatt
    14161 tttgatggtc ttttctactg gtgtttggct atttgccagg atctcaaaag gcgtgattgt
    14221 ttgcttttca atcatttccg cattatcagg agcttttact tcttctaaat tatattttcc
    14281 aacttctaaa tgattaacga tcaactggcc tttttcaata gatgcctcgg caaagtcatt
    14341 gttgccgatg tcataagaat gaccagtaat gaaatgtttg gctttggttt gatcagttgt
    14401 ccaagtgtac aatccatctg tgacactttg gatgtatttt ttgacgcttg gtgttccttc
    14461 ttctttagaa ataataaatt ctgctccatt tagtgcttcg ttttcggcag taccgatttt
    14521 tgtaactttc aacgttccat cattaccgac tgtattttta gggtagagat ggatagtatc
    14581 tagttcttct gtcccgtatt tataagagcc atctgcttgt ttgatcatct catatacagg
    14641 gaaagctaaa accatgtttg cggcagctga cactccgtct tttggttctt ctttgatcgt
    14701 gtagactgca tctttcccat tttgtttttt aggtaaagat aaagtgacat ttccatcagc
    14761 atctgtcgtt cctgaagcaa ctggtgtacc aggagtcaaa gactggactg cttgttttgc
    14821 tgcatccacg gacgctcctt tatctcgttg cgcataaaat tcttgagtga cgttataaac
    14881 tgaaaatgaa atatcggcta atccttggta ttgatcgaat tcgctcattt ctttcccgct
    14941 gttttggatt aaaggatcgg gtaaatcagt cattttcttt ttatgaagga tgacttgagc
    15001 tgctgtctcc tctgcaaaca ctttttttgc gccgaagctg tttgtgagta atggtaaaat
    15061 aaggaaaagg actcctaaca taacgtttat ttttttatga tttttcattt tttcactcct
    15121 gttctttttt tgataaacaa ccagattgca aagcttgcga ataccatacc aacaacgcct
    15181 aaaagtgtat ttttcgtttc gtttgttttt ggaagaaatg gacggctatt ttctttttta
    15241 ttgactactt tcaatatact gtccgcctct ttatcctcag aaagaaaagt tgaaatggta
    15301 aacggaattt ctgtttcact taaaatataa ccagaaggtg cttcgatctc ttttaatcga
    15361 taacttcctg ttttcaaccc ggaaattgaa aaagcgccat ttttatcgga aatcaggtga
    15421 agcgcatctg attcgttctt tgtccacttg tatccgttgg ctgtttgctg gaggtaattt
    15481 cctgctttgt ttttaataag gaatactgcg ccagctaatc gtttatctgg tttatttgtc
    15541 tcgattttga caaattgctt actccctgta tatacagaga ctttctttgt actgacacca
    15601 aaaccaaaat ccagtgttcc gttgttgttg atttccttgt tcgcctgtgc tgtactgctt
    15661 agctgcatct gataagaaat ggtcagtttt tttccagcat atttttccaa cgaagggatc
    15721 gaaaataaaa catcaaatcc gtgaggtttc ttgtgtatga caaagccttc tgtcagcttt
    15781 tctccattcg atgaaatcgt taaactatta ggtaaaaacg ttaatgcttc atccgcacta
    15841 tctgacaatt cgaacttttg atagtcaagg atatttacag gaattgtcgt atgcaaggaa
    15901 taagtgattt tttcaccaat cgtaaaatca tttctaggct cttctaatac cttctcaaaa
    15961 ggtggatcag ggtagtcgtt ttcttcattt ttaggataca aatggatagt tgaaagtttt
    16021 tgattgtttt gtccatgtac aggaagaaca actaccatat tctctgcctt ttctttgacg
    16081 acttctggta ctttggattc aatgaaaaga tacgctttat ctcttttttc ttgatcttta
    16141 gcggccagag aaaaagaagc gataccatct tcgttgttaa gagttgtagt tgttgcttct
    16201 gcggtaaaca taccggaaga cgcaccgttt tttgcgatct ctgcttgtgc ttcttctacc
    16261 gttttgccct tttcccgtag atggtaaaaa gaatctgtga catcataaac ttggaatgtg
    16321 acaccattta atcctcgata cgtttgtaat aaagcttttt cttgtccgtc atttggatga
    16381 tttttcggca gttgcccgtt tgggaaaagc aatttgtgta aagtaatctg aaccatttct
    16441 gtttctgttt ctgttgctac ctgagtaaaa gctggtttaa atagtaacaa gaagagacac
    16501 atactaagcc aaccaagttt tttcatattt agctgccccc tctttctttt ttcaaaaaaa
    16561 gataccaaat agaaaacgca caaccaatca tccctactag atagattcct aaacggccaa
    16621 ttcctcccgt ttcaggtaat ggtacttttg cctgattcgt gatgtctaaa gaaatctggt
    16681 tgtttttggc tcctggtgac agaacagatt catgatcttg tccatccact tgaattgacc
    16741 catcttcgtg tataactata gtaactggct cttttagacc ttggtatcct tctggtgtaa
    16801 aagtttcggt cagcgtataa gttccaggtt ttaaattttc gaatagaaag gtatctgttt
    16861 cttgtccatc ttttggcgat tctaagtcca tttctggtcc ctgcagtctg aattttgctc
    16921 cttttaatgt ctgtccgttg tcttcttttt tgtgtaccgt tagatcaaac gcttttagtc
    16981 gattttgatg agtgagcgtc catacattat ttgtcatctc ggtatttttt cccgtgtaaa
    17041 tgatttttcc atatttatcg atttggaatt cataatttcc cggcgaagta tcatatccgg
    17101 caggaccagc tgtttcaacg actcgatatt taccaggtgt gagtgaatca aaactggcaa
    17161 gacctttttc attcgttgtt tggctgtcaa ttggctgata agtaccattt gcttcttttt
    17221 tctgtaggga aaatgctgct cctttaagat ttatctcttt gtccgtccct tgcatcgcat
    17281 acttacgtac tgctacagga acttcaacaa aaggattttc aatagtcaac tggatcgtat
    17341 catcggaagt agtgactgtt tttccatcaa tggttaccgt accatcagaa gcgatcttga
    17401 tttcccaagt agtctttttg cttaatccat gcccttctgg agcttttgtt tctgtcagcg
    17461 tataggtcat ttctttttgc aatttgacat tttctggaag agaataggtt ccgtcgccat
    17521 gatctgttag taaagtatca atagaatctc ctgttaattt gaaaacagcg ccaataagat
    17581 ccttttcacc tgtagaggaa tttttcgtta ttttcaagtt taacggtgtg aattgtttag
    17641 tatttttcca tgtcattgca tctatttgtt gagaatcgta tcctggtaca ggtaattctt
    17701 tgattgtttg gtaactgaat gcttgacctt gattattgta ttgaggtagt gataatatct
    17761 cttgataact ttctccgcta tttgcagata atttgtcaat gtctgcacgt tcccacgtat
    17821 ttgttgtatc tttagctggt ttaatgattc gaatatatcc gtttttccaa gctgcagcat
    17881 ttgtcgtatg ttcccgttga atctcaaaag taacttgatc tggacgatca gctagattgt
    17941 tgtcaaattc ttcccataac tttttgatgt gaagactgac tccgggagct ttagcagatg
    18001 gtataccgaa ttcagctaat tcattggtat caatgtttgg ctggaaagtt gtcctgccgt
    18061 tcatttgata ccagaaattt ggatggaagt cctcattttc tgtttggatt ctcacttggt
    18121 aatggatttg gatttcttgg tcttttccta aatagatctg attgctcttg atggtatttc
    18181 cttctatgga aatagatgga gtgaccgttg taggacttgt ccccacactc ttgactgaaa
    18241 gtgtaccagg ctgataaatg aatggttctg cgattggatc atttatttgt ccattgctta
    18301 cagttgctga gatctgtaca gcttttttgg ctaggtattc agagatatct gttgcatgat
    18361 cagctgattc atagtaaaga tcgccttttt catctgatga aaccatttgt cgcatacgag
    18421 actctacttc tgcttttgag agaccagctg ccggatcgct ttgaagttgg atgccaagac
    18481 catgtatttc gattcctcgt tctttgagtg ccatcgcttc tccgatggtt gcgataaacg
    18541 tactgtcgat tcttctggat agattgtttt ggtcaggtgc atcatagatt cttgagatta
    18601 gagaagtatt tcccggccga tcttgcgtat tagaaaactg agttccgtaa taattgctgc
    18661 ttgattgtgc gtgtacccgc tgtactttat aggaaaatgt tggtacacca tccgtcagca
    18721 aaacgatcac ttttttatgt ccatttggaa cggatagcat gcttcctgca tctcttagtg
    18781 ctttttgtgt aaaagtacca ccatttgtcc gtgaaggtgt aatggatttt acttgatttt
    18841 tcactgaatc aaatgaaccc atctgtactg caccgttact gtagctatat ccttcgcttg
    18901 agtagccgac atatcccata ttgattttgt ctgtgatacc gctatctgct aaagtatcga
    18961 caaaacgatc gacaccaatc tttacttcac cgatccgatt attgtcgttc atacttcctg
    19021 accagtctac gaccaatacg agatcaagag gcgtgatatc tttttgtaca tttccacgag
    19081 cattcaaata aacatcaaac aatccgggtg tacttgtttc ctttgcatac tttcgtatcg
    19141 catagtctgc ttgattaccg gttcctccat attcgatata cgaatgggtc cgatcattag
    19201 gatctccatt ccaagaattt ataccatccc attgatttgt tccgttttta ttgccttgat
    19261 gatcaagaac atttgtattt cctgtaggtt gccaactggc tttaggataa gtgccctgat
    19321 catctgttgt atattctgta ggaatcgttt gattagatgg cacactcaca gctggcaagg
    19381 ataatgtagg caatgtaaat gggctgacag aattttcgtt ttcttttgat gattcttctt
    19441 ctatttcgtc tggctttggt actgacacat ctgtatcttt cttattttct gtctcatcaa
    19501 taatgtcata ttctttatta tcgacgatca gcttgtttgc ctggctgtgg taaagtgctg
    19561 gatcgattgg aaaactcaga tcgatagttt gtttagtgtt tgatgagatt tccaacgtaa
    19621 ttttcccgct atttacctga taagcatagc catctccttc ttttctttcc acatcactta
    19681 agtaattttc gactagacca atttcttttt ctatcttttc agcactggtg ttattcgcat
    19741 ttagcttgat gttcagtgct ttttttccag actgatccga aatgacttca gctgaaattg
    19801 tttctaaaac tgttggatca tctgtagtgt ctgctattgc agataatggc acaaagtttg
    19861 ataaactcaa tattatcagc atgaaaataa ctttcagttt cttccctgtg gtcgtcattt
    19921 ttcccctcct ttttcttttt ttctgttttg acgtgaatag tgaaaattat taaaataaac
    19981 aggcgttaca taattttatt tattttaata tgataattat tatacgaagg gcgctaaagg
    20041 gaatcacacc aattttcata ccaattggtt tcatttatga agttgattcc ttcgattaat
    20101 gagcgtttca ttgaaagaaa agggttgagg gagaaaaaca tatgatcagg ttgttggaat
    20161 taaactatag aaagatggaa aaaatcattc gaattctgtc catttctgac aagtggatga
    20221 ctaaaaaaga acttgccaaa cgaattggta gttcagaatc tacatttgta aggtatatcg
    20281 aagagatcaa aatccgctgg ggaacggatg taacgattca atcttcacaa aaattggggt
    20341 atcgtcttga acatttgaat gtaccagctt atttaaatgt tctgatggaa atgtcgcaaa
    20401 gttctacaaa cagtcgttta ttaaatgaga ttattgtcaa tccgggtaaa acgattgagt
    20461 attattgtga aaaaatttcc atcagccggt cttcttttac acgtaagttg aaacaatgca
    20521 atcaaatttt agaaagctat ttattaaaag tgatcgttga ccaaggtttt cagttaacta
    20581 gccttaaaag tgagctccag ttgcgtatct ttgttacctt tttcttttta agttactacg
    20641 gaagacgcac gttgccattt ccaatcgaaa aaaagaagat caaagaaatt atggtcaaga
    20701 ataattgtca gatgaatttg tttcaggaag aaagcccata tgagcaatct ttctttatta
    20761 tgtattttgt tgtgcatctc atgagagaat cccaaggaac tccatttgaa tggaaagctg
    20821 gagactctta tgtacagttg ataaatatcg ataaaaaaga cttcttaatc ttgaaaaatc
    20881 tcttaggaaa attgaagtac agcagctata taaaagtagt gaactatttt gtcaatacga
    20941 ttttttcaga attttcggag aaagaaaaaa atgaaatcag tgagcagata cgaaaaaata
    21001 tgtcctactg ttcgttttca tccgctgatt gcaaagaaaa aaacgaagaa tatgttgttc
    21061 aattattaac gcaaatttat tttttctccc gtattttccc atacgatacg actcatttga
    21121 cgatccgtgc aacttacttt gcacagcaga tgcaacaccg ccagatacgt ctatatgctg
    21181 gatttcgtgc agaacttcaa ttttattcca ctctactgaa tcagaatctg atttattatt
    21241 tatctagcta tatcttttgg atgcttatcg gtaatcctga aattcaccat tatacttctg
    21301 ataaaaaaat actgattatc agcgacttaa gtcttcgaca tagtcaatat attgaagaat
    21361 atatcagtga tattcttgct gtgcataaaa ttcactctga gacaactgct attactgaag
    21421 atcagctgtc gaaatacaat cttctcgagt atgatctgat cgttacgaat caacccattt
    21481 tgaatgccca tgttcctcat atattgattg atgatagtgt gtcattcgca aatgaagaag
    21541 aactcatccg cttattcgag ttatgaataa tcaaaaaaca gctatgtata aaccaccctg
    21601 ataaaaattt caggacaaat acacatagct gtttcttttt attgtattcc ttcagcaatc
    21661 caacgagatt tatagcgaaa gtcttttaac aactcttctt ttgtccaatt atttgcaatg
    21721 agatccgtca aagtgttcat tacgagggtc atggaaaagt ataggaaact aactgcttct
    21781 tccgacgatt gaatggagaa atgattgatt cttaataatt ccagccattt ttcgttcatt
    21841 ggagaatcag ccgatagttc tctacgtttg gttgtctgct gatcatttcg ctgggttaac
    21901 aagtataacc tttgccaata gatactttcg tgatctaagt cgcagcacca ctctaaatat
    21961 ttttcgatcc ccaaaaagaa atgttgtttg ttttcgctaa tgaattttaa gatatcttga
    22021 tggactatgt gagaactgct tttgatcgta tacaaataag catcttccaa atcttgaaaa
    22081 tatttataaa aagcaccgcg cgacatcccc atcttgtcaa cgatttctga gactttgact
    22141 tggctgatgt gctgtgagca aaatatctcc agtaataggt catcgattct ctgtttcttt
    22201 gcgttcgata aattgaaaaa agtttctttt ggcatccaca tctctccttt atctctgatt
    22261 atacgtggat agcccttcat tgtcatgaag gattcattcc ttctttttct cttcttctgt
    22321 caagtaccca tcttccattc gataaacgcg atcactccat tgaatcatac ggacatcatg
    22381 agtaaccata atagtcgctt tttgtttctc atgagcttct ttaactagta atttgacgac
    22441 ttcatatgca tgatctgtat ccaaactagc tgttggttcg tctgctaaga tcaagcttgg
    22501 ctcattatat aaagcgcgag caattgccac tctctgtctt tctccaccag aaaggtcttt
    22561 aggataacta tttttaagtg actggatatc taaagattgc agcaaggaat cgatttttgt
    22621 tgaatcttct ttttttgaag taacttggtc aactagttca aattgttcct ttaccgttaa
    22681 aaaaggaatc aaattagagc tttggagaat aaatcctatt tctttaaagc gtaaatctgc
    22741 tcgttttttt tctggaagct cagttagtga gtgaccgttg atcactattt ctccggaagt
    22801 cggtgtttgc aatcctcctg aaatggtaag gaaagtactt ttacctgaac cagaaggacc
    22861 aatgatgctg acgaattctc cttcctttac ataaaaatca attgctttca aagctgagac
    22921 ctttgtatga ccagaaccaa atgttttggt aacttttttc atcgttaata tttttttcat
    22981 ttttattaac ctcctattgc tgtaattggg tctactttgg ttatcgtacg tatcgaaaac
    23041 aatccgccta gcattgcgac aatgatcaaa atcccactat atagcaacca ttgtgaccaa
    23101 aaaacagcaa aaggcatcgc gcttggtaaa atcagactag tcaaataagc aaacaaaaga
    23161 gcaagcagaa cgcctaccac cccaacaata aaggactgtg ctactaaaga tttagcgatg
    23221 aagaaatttt tgatcccttg tgctttcatt actccaaaaa tagcagtctt ctgaagtgtc
    23281 atcacgtaca tgaaaatacc gaccacggca gcaaccacta agaacaaaaa gtatatcatc
    23341 gcatttaagg tcatattttg ggcagaatag ccaggaatac tttcaatgaa tgtcccaata
    23401 gttaataact gtagaccctt cgatgctttt tctttcgaaa ttttagctga atcctttatt
    23461 acgatcccat tgatcggctg ttcttcttca gaagcaaacg gctgttgtcc atacttcaaa
    23521 gcagtccacg tatctaggga cgcatagatg acgggagaaa ctgtgtaata agtttcagga
    23581 aagataccga caatcgtcaa aggatcgtcg taactgccaa ttttgatcgt atctccaatt
    23641 ttatagcctg aatcagccag attttgagag atgatgattt cattctttgt tttaaattca
    23701 tgccctttcg tgagttttgg taataaaaat gcttctttcg ttgtgccgaa aactgtaaca
    23761 ttttctttgt tttttccttt gattgctccg ctgtacaatc cgattggtgc tttctctcct
    23821 ccttcaatgt atttcagatc tcctcttgtt aattgtgaag ctgcaaatac ttgatttgca
    23881 tcctccgaca aaacaatctc ttgtgcgtcc caatcatcga ttgctttttt aaactcttct
    23941 gaaagtccat tcgctagtcc tgacaacatg aatacgacat acgcaatcaa gaacataata
    24001 ccgacgatca agccatatcg taatttagaa tagcgaattt ctttgatagc tagaaacatt
    24061 tgtttttcct ccctatgata gattgatagt gacaaaatgt cacttgttga atagtgtaac
    24121 tctaaagtga caatttgtca cttgtgttgt ttttttctta tcaataaatt gtctaagaca
    24181 tctttcgata aaaccttaac atgagtcata aaaaatttat ttaagcctta tttatgcttt
    24241 ccatgataaa ctaaagtgac caaatcaatg aggtgggaaa atgattaaac tattagtagt
    24301 agaagacgat aaagtattat ccaataatat aaaagaaata ctcgctgcaa tcggcgagat
    24361 aacacaagtt tatgatggta gtgaaggact gttcgagttg gaaagtggag tttatgatct
    24421 tgcaatcttg gatttgatga tgccggaaat gaatggatat gaagtgttag caaaaatacg
    24481 gaaagaaaaa atacagactc cagtattgat tttgactgca aaagatagtt tggaagataa
    24541 gattgaagga tttgaacgag gtgcagatga ttatctaaca aaacctttct atcgagaaga
    24601 actgatcatg cgcgtgaaag cattattgaa acgctcgcta ggtctctttg atgaaaatgt
    24661 tctgaagtat aaggatatca gttgtgattt aaaaagcaat gaagtcttgt ataaagaaca
    24721 agttttgccc atacaaggaa aagagtttga attgctcgtt tattttttac aaaataaggg
    24781 aatcattttg acaaaagagc agatatttga ccggatctgg ggatttgatt ctgatacgac
    24841 gattacagtt attgaagttt atatgagcaa cttacgaaaa catctgcgaa gtactggatt
    24901 ggataaagaa atcaaaacct tacgtaatgt cggttatata ctgcaaaggg tgtgatgcaa
    24961 tgaatggaga tattacacga aagcaacgta gtcgcttttt tgcgacaaat gtagcagcat
    25021 ttgcttttat cttttttctt ttgggattca ttactttaca gatattaaac caatctgcat
    25081 acagagaaac agatctgtca ttagagaaaa taaattttga ttctcgaaca gtacaattag
    25141 agatacaaag atatcagcaa ggcgatccct ttttaaaccc gactcaaacg gaacaaaaca
    25201 gaacaaacat ggaacagcca ttaatggaac catcaaatga ccgttttaac actcaagtga
    25261 tcttgtggtc taaaaatggt gagatattga ataaagcagc tattggtggg cgtttcaacc
    25321 aaatcaaaga attaaaaatg gatacgaaaa atctgaatac catccaaaat attgaattaa
    25381 atgaagacag tggctcatct gccctctctt tccgttcgat tacgaaaaaa gcggagacga
    25441 atcaagatgg cgttgcctac atccaaattt tagaaaatac aaatcaaatc aagaattcat
    25501 tagcgacttt tcgcacgatt atgattttgt gtatgattgt tttttggatt ctctctattg
    25561 gtatcagtta ttacttgtct agtctaagca tgcgccctat tattctttct tggagaagac
    25621 aaaaagaatt tgttgagaat gcttctcatg aattgcgcac accgttaacg attattcaaa
    25681 atagtttgga acatcttttt accaagccta atcatactat tattgaagaa tccgaaagca
    25741 tcgctcaagc attgtcagag acgaggcgcc tcactggatt gacttcggat ttgctgacaa
    25801 tcgctcggaa tgattctgat cagcagctgc tttcaaagca aatgatcaat acacaagaat
    25861 atatcgaaca acttgttaaa ccatttcaag agatggccat catagatgga aaagagttta
    25921 ttctccataa cgatgcaaca ttagaagtac caattgatga aaaaaaaatc catcaagttt
    25981 tggttatttt gctggataat gcattaaaat atacgaatcc agaagataag atcattttgg
    26041 attcatctgt taaccataaa gaatggctga ttcacgtaaa gaatactggc ccttctatca
    26101 gtgaagaaga tcaagcaagg atttttgatc gattttatcg ggaagatcaa tctcgggcga
    26161 aagagactgg cggatacggg cttggcttgg caattgcaaa acaggtaatc gaacagcatc
    26221 atggacagat ttctgtatcc aattatcttc cacaaggagt cgattttaaa gtccaattgc
    26281 cgttgaagcc taaaaaataa tgcttatccc taaaaaaggg ctgtgacaaa aatcttgtca
    26341 cagccctttt ttgttgcgaa taaacggtgt tccagaagta gcttcttcgg aaataagccg
    26401 aaatttcttt aagctgacca cttctgtcac aacctcttta gcttacgctt acgatttttt
    26461 attgcggtct tcaatgtgta catcaccgct tgtgtcaata tccaattctt ctcggctaac
    26521 atcttctgtc actttttcaa catcttcatg ttcttcttta tgaatcccaa cttcttcacg
    26581 aataactgta tgtttgctta catctacttg ctcttctttg attgggatag taatcgtgtc
    26641 atcttccaat ttttcgtctg ttccctgtga agattgatct gttactggtt tgcgttcgat
    26701 gacgatttct tcacgtttga ccggtacttc taccgtttca gtatcgttga ccacatgttt
    26761 gtggatgtcg acttctccag ttgtcacatc atgtgtattt acatctaatt tttcttcttt
    26821 tagttgaatt gtatcatcat ctagatttgg tttgcgatcg atgtcttcag tcttgcttgt
    26881 acccattgta tcagtctcgc caggtacgtc catcggatca gttcctggtg tcatattcaa
    26941 tggatccgtt gtattttgaa agcctgtcgt gccacctacg tccattggat ctgttccagt
    27001 gccagtttct aatccagtcc ccattgtgct tgctgggcta acagtatctt gtgtatccat
    27061 tgtatcttct gttgtttctg gctgacgata gccttttact gtgatgacaa attttccatc
    27121 agaaatatct cctctatatt gatataaagg atcattttct ggtgtagccg tctcagaatc
    27181 ataggtatca aaagaaaaag tatcttttat tttttcccat aaagaacggt cttcttcacc
    27241 atccatccga ttttcatctg tttcaacatc tataccagac aatccgtcaa atcctagtct
    27301 agatgctgct tcatcagtag tataaataac gatatcatct cgttcatacc cttcgttacg
    27361 caaccgttca attactgata atgcttcttc cctcgtacta tagcttccga tgaccgttaa
    27421 atttttctct tccatgtaaa ttcctcctag caaatagatt tatgattggt atattgttac
    27481 ttataaattt attctatagg agacgattgt tttctacaaa tatttagatt ggaatttgat
    27541 taaaacaatt taattgaaat ttgaaaacat ttatgttaat gaaagtcata ttctaataaa
    27601 atgtcatttg tttctatatg aatttttatg aaaaatttca tataatttcc actcgttgtg
    27661 atggtttaat ttatccaatc catcaataag caaacaactt atataaaaaa ggattaattc
    27721 tcaatataat tgctcctacc atagaataaa tcttcatgta aagtaatgaa gtaccaacta
    27781 tttctaatac ttctttaaga attatcccaa caatatcgtt agacaaacca ttattgaata
    27841 aatggagagc caatcgattc tgaaaaaatg ttttctaatt tttcggaaat aaaagaaaga
    27901 gcctcctgcc attagaacga accaaatcca tttcattgct catgaagtaa ccacatagct
    27961 aaaaagagga taaatcaatt aaaagatcaa aagaatgact gcactaataa aataactaaa
    28021 aatgtatctt cttacttcat atcttttagc tagtacttag ttaaaaattt gcttcctaag
    28081 atcaagacaa actgtctatc ttcatttgat gaaatgcggt aaaatataga aaatgaacac
    28141 tattggaggg aatttgtaat ggacagcaaa actagaaaac aactgcaaga aaagttaaag
    28201 caacgtacac acttgctccc ttccgtcttt caacagtttt tagaagaaaa tcgttcttcc
    28261 ctttcattag gcagtcgcta tgaatacgca aaagattttc atctgtttac tgattatttg
    28321 agaaaagtat tttctgaaga agtggatgat cagctgatta tccatttaga aaaacaagat
    28381 tatcagaatt tcttagctaa aatctatcga catactcgtt cgttccaaac tacagcgaac
    28441 caagaaacgg agcaattgtt tgaaaatagc tattacggga tttcaaggaa gcaatattca
    28501 ttaaatcatt ttttacgatt tttgtatcaa aaaggactga ttgaagaaga gatttctctt
    28561 ttgggtacaa gtttaccgga aacaaccaaa gcagctccgc gatatatcga tgcagaactt
    28621 ttcaaagatt ttgagcattt gtttatcccg attgaaggct ttcaaacaag cagagaagct
    28681 agctttgaag aaaagaatag accgaggaac cttgcaatta ctgccattct tctgtattgc
    28741 ggattaaaga tccatgaagt agtagaactt aaacgtaaag atgtatcttt gaccaagcag
    28801 attcttaatc tgaatagaaa agaaaacaga ctgaataaag taccaatacc aaaagaagcg
    28861 atgccatttc tggagaacta ttttaagtta acagcacaaa atacggacga aaattctttt
    28921 gtttttcgtt cctcacatga tcagcaaatt tctcctcgga ctattcgcca aattttgagc
    28981 aaaattacag tatataaaaa cgtatcgcca gaactatgca gaaaaacata tcgttattat
    29041 gcagaactat atttagatga tgctgacgcg gtaaattatt tatgtggtaa tcgatacctc
    29101 tcatcccatt cttttcaaga tatctgggaa aagatggttg atttttctta tcacgaatta
    29161 gcggcattcg ttcgggtttc ttccatataa aacaaatgta tgatcttttt ttcacaataa
    29221 actatgttat tatataaagg attatgttac gattatcttg aatttgtata ttacttaaca
    29281 aaagataatg gagtgtgaat gatggagacc ataacgtatt cccctttgaa cttatttacg
    29341 aattttcaag aagctgcagc taacttttcc gagaccccga ttatctttga tgagccactt
    29401 tcagctttcc cagaattagg acttgaaaca acttacaaaa aatgctgcga aagtgtgttg
    29461 aaacgggctt atcaattggc tcatcttgga gtgaaatccg gagacaaagt tattatttat
    29521 aagagttccg cttttgacac ataccttcta gctgtttctg tgtcttacct tggtgcagtg
    29581 cctgtcatga cttcttatca tctaccaaca acaacaatgg aagtatttat cgatcgttta
    29641 gaagaccctt tcattttatt tgatgatgag acaaaaaagc gagtgagaga aatttcaaat
    29701 ggaacaaaat caaaacagat tcc
//
LOCUS       DADGKS010000029        29640 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.029, whole genome shotgun sequence.
ACCESSION   DADGKS010000029 DADGKS010000000
VERSION     DADGKS010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.029"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..1086
                     /locus_tag="JXV47_001414"
     CDS             <1..1086
                     /locus_tag="JXV47_001414"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HAX1487466.1"
                     /translation="QEMGIPVITEVELAYEVAECPIIGITGTNGKTTTTTMTGLLLNA
                     GADQGIARLAGNIGYPASGVAQEAKSEDKIVMELSSFQLMGITDFRPHIAVITNIYEA
                     HIDYHGTRKEYVKAKWNLQKNMTEKDYLILNWNQSELQELAQRTKARVLPFSTKEVLE
                     DGVYADDYSIYYKKEKIMEISELGVPGKHNVENALAAISVAKLYGISNEAIRETLHFF
                     HGVPHRTQYVGEIQGRKFYNDSKATNILATKMALSGFETSKVVLLAGGLDRGNTFDEL
                     IPSLKGIKAMVVFGQTKEKLMDAGKKAGIETIVTADSVEQAVPLALENSTDGDVVLLS
                     PANASWDQYPNFETRGNRFMEAVNRLK"
     gene            1112..2200
                     /gene="murG"
                     /locus_tag="JXV47_001415"
     CDS             1112..2200
                     /gene="murG"
                     /locus_tag="JXV47_001415"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HAX1487467.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            2215..3435
                     /locus_tag="JXV47_001416"
     CDS             2215..3435
                     /locus_tag="JXV47_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HAX1487468.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            3591..4916
                     /gene="ftsA"
                     /locus_tag="JXV47_001417"
     CDS             3591..4916
                     /gene="ftsA"
                     /locus_tag="JXV47_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HAX1487469.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            4939..6180
                     /gene="ftsZ"
                     /locus_tag="JXV47_001418"
     CDS             4939..6180
                     /gene="ftsZ"
                     /locus_tag="JXV47_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HAX1487470.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            6197..6874
                     /locus_tag="JXV47_001419"
     CDS             6197..6874
                     /locus_tag="JXV47_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HAX1487471.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            6888..7487
                     /locus_tag="JXV47_001420"
     CDS             6888..7487
                     /locus_tag="JXV47_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HAX1487472.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            7502..7789
                     /locus_tag="JXV47_001421"
     CDS             7502..7789
                     /locus_tag="JXV47_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HAX1487473.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            7838..8620
                     /locus_tag="JXV47_001422"
     CDS             7838..8620
                     /locus_tag="JXV47_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HAX1487474.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            8641..9348
                     /locus_tag="JXV47_001423"
     CDS             8641..9348
                     /locus_tag="JXV47_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HAX1487475.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            9610..12408
                     /gene="ileS"
                     /locus_tag="JXV47_001424"
     CDS             9610..12408
                     /gene="ileS"
                     /locus_tag="JXV47_001424"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HAX1487476.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(12457..13983)
                     /locus_tag="JXV47_001425"
     CDS             complement(12457..13983)
                     /locus_tag="JXV47_001425"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HAX1487477.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(13998..14645)
                     /locus_tag="JXV47_001426"
     CDS             complement(13998..14645)
                     /locus_tag="JXV47_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HAX1487478.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(14829..15158)
                     /locus_tag="JXV47_001427"
     CDS             complement(14829..15158)
                     /locus_tag="JXV47_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HAX1487479.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            15335..16063
                     /gene="sfsA"
                     /locus_tag="JXV47_001428"
     CDS             15335..16063
                     /gene="sfsA"
                     /locus_tag="JXV47_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HAX1487480.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            16079..17092
                     /locus_tag="JXV47_001429"
     CDS             16079..17092
                     /locus_tag="JXV47_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAX1487481.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            17092..18369
                     /locus_tag="JXV47_001430"
     CDS             17092..18369
                     /locus_tag="JXV47_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAX1487482.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            18432..21134
                     /locus_tag="JXV47_001431"
     CDS             18432..21134
                     /locus_tag="JXV47_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAX1487483.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            21286..21603
                     /locus_tag="JXV47_001432"
     CDS             21286..21603
                     /locus_tag="JXV47_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAX1487484.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            21633..21953
                     /locus_tag="JXV47_001433"
     CDS             21633..21953
                     /locus_tag="JXV47_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAX1487485.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            22061..23521
                     /locus_tag="JXV47_001434"
     CDS             22061..23521
                     /locus_tag="JXV47_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1487486.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            23589..23810
                     /locus_tag="JXV47_001435"
     CDS             23589..23810
                     /locus_tag="JXV47_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487487.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            23841..24023
                     /locus_tag="JXV47_001436"
     CDS             23841..24023
                     /locus_tag="JXV47_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HAX1487488.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            24023..24436
                     /locus_tag="JXV47_001437"
     CDS             24023..24436
                     /locus_tag="JXV47_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HAX1487489.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            24559..25740
                     /locus_tag="JXV47_001438"
     CDS             24559..25740
                     /locus_tag="JXV47_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1487490.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            26129..26202
                     /locus_tag="JXV47_001439"
     tRNA            26129..26202
                     /locus_tag="JXV47_001439"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:26163..26165,aa:Arg,seq:cct)
     gene            complement(26271..27410)
                     /locus_tag="JXV47_001440"
     CDS             complement(26271..27410)
                     /locus_tag="JXV47_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAX1487491.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(27709..28344)
                     /locus_tag="JXV47_001441"
     CDS             complement(27709..28344)
                     /locus_tag="JXV47_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487492.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(28457..29092)
                     /locus_tag="JXV47_001442"
     CDS             complement(28457..29092)
                     /locus_tag="JXV47_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HAX1487493.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(29126..29587)
                     /locus_tag="JXV47_001443"
     CDS             complement(29126..29587)
                     /locus_tag="JXV47_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4429 domain-containing protein"
                     /protein_id="HAX1487494.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
BASE COUNT         9768 a         5092 c         6036 g         8744 t
ORIGIN      
        1 caagaaatgg gtattccggt aattacggaa gttgagctag cttacgaagt agcggaatgc
       61 ccaattattg ggattacagg aacgaacgga aaaacaacga caacaacgat gacaggacta
      121 ctactgaatg caggagcaga tcaaggaatt gcacgtttag cgggtaatat tgggtatcca
      181 gcaagtggtg tagcgcaaga agcaaaatca gaagataaaa ttgtgatgga attgtctagc
      241 ttccaactca tgggaatcac agatttccgc cctcatatag cggtgattac caatatctat
      301 gaagcacata ttgattatca tggtacaaga aaagaatatg tcaaagctaa atggaacctt
      361 caaaaaaaca tgacagaaaa agattatctg atccttaact ggaatcagtc agaactacaa
      421 gaattagcgc aaagaacaaa agcacgcgta ctgcctttct cgacaaaaga agtgttggaa
      481 gacggtgtgt atgctgacga ttactcaata tactataaaa aagaaaaaat aatggaaata
      541 tctgaacttg gcgtaccagg taagcataat gtagaaaatg cactagctgc tatttctgta
      601 gcaaaattgt atggtatatc aaatgaagct atacgagaaa cgttgcattt tttccatggc
      661 gtaccacatc gtacgcaata tgtaggagaa atccaaggca gaaaatttta taatgattca
      721 aaagcaacca atattttagc gactaaaatg gctctaagtg gatttgaaac gtctaaggtc
      781 gtgttattgg ctggcggatt agacagagga aatacatttg atgaattaat tccttcatta
      841 aaaggaatca aagcaatggt cgtatttggc caaacaaaag aaaagttgat ggatgctgga
      901 aaaaaagcag gcatcgagac aatagtaaca gccgattctg tagaacaagc agttccttta
      961 gcattagaaa acagtacaga tggtgatgta gttttattat caccagcgaa tgccagctgg
     1021 gatcaatacc caaattttga aactagagga aacagattca tggaagctgt gaaccgatta
     1081 aaatagaaaa agtagaagcg agcgataaaa aatgaaaatt ttggttacag gcggaggaac
     1141 agggggacat atttatccag ctcttgcctt tgtcaattat gtaaagactc aagaaccgaa
     1201 tgctgaattc atgtatgtgg gagcaaaacg aggtctagaa aacaaaatcg tccctgatac
     1261 aggaatgcct ttccatacct tggagattca aggatttaaa cgaaaaattt ccatgcataa
     1321 catcaagacg gtccgattgt ttcttaagag tatccgtcaa gcaaaaaaaa tcctcagtga
     1381 ttttcaacca gatatcgtta tcggtactgg aggatatgtt tccggagcgg tagtgtacgc
     1441 tgcagccaaa atgggtattc caacagttat ccatgaacaa aacagtgtac caggtgttac
     1501 caataaattt ttaagccgat atgtggatcg gatcgctctt tcatttaaag atgcggcttc
     1561 cttttttcct gaaaacaaag cagttcttgt aggtaatcct cgagcacaag aagtagcaga
     1621 tactaaaaaa tcagatattt tgaaaacatt tgatttggat ccagaaaaga aaacagtctt
     1681 gatttttggc ggtagtcaag gagcacttaa aatcaatcaa gcagtatcag tttttttaag
     1741 tgaatatatt ccttcttctt accaagtttt gtatgcttca ggagatagat attatgaaga
     1801 gatcctaaat aaaataaatc ctgaaataca aaatattagt gtccagcctt atatcaaaaa
     1861 tatggcagag gtcatggctt ccagtgatct gctggtgggg cgtgctggtg caacttcgat
     1921 cgcagaattc acagctctgg ggttaccggc agtgttggtt cccagcccat atgttacgaa
     1981 tgatcatcag actaaaaatg caatgagtct tgttcacgca ggagcagcaa aaatgattgc
     2041 agataatgaa ctaacaggtg aatcactaag tcagacagtc aacgaaatca tgggtgatga
     2101 agaattgcaa aagcaaatgt gccgagcttc taaagaacaa ggaatccctg atgcttcaaa
     2161 acgtctttat gacttagtaa aacaaataat caaaaaataa aggcggtggt cttagtgagt
     2221 aagaaaaaag aaccaaaaaa attgtctcat ccgtcttctg atgaaaacaa tttgactcct
     2281 tggcaaaagg ctaaccgaaa atatctggca gaacaagaga tgaaaaacca agagccaaaa
     2341 aaagaagaca taacattaga tacacccctt tcagattctg aagaagaaaa aacggttcaa
     2401 gaggaacagc aagaagaaag ccagtccgag aaaaaaatcg aattttttga agagatcaag
     2461 caaaagaaaa acggtggacc atataacggt tcttttttga accggctgcc caatttaaaa
     2521 agtcaacggc acaaagtact atttcgtcgg ttagctttga tcatcactgt attgggtata
     2581 ccgctgattt ttttgatcta ttatgtttct ccttatagca aattacaagc agttgcagta
     2641 tcaggcaata agacagtcaa cagccaagaa atcatctctg atacaaaatt gtcattagga
     2701 gaaaatgttt ggggacagta ttttcatcga tctacttata tcgatcgcct taaaaaagca
     2761 cagccaagaa tcgaaacagc aaatatacat ttcaaaggga tgaatgaatt cgatttggat
     2821 gtaacagaat ataaagagat tgctttgatc gcaaaaaaca atcaatacta cccagtgatt
     2881 gaaaatggaa cagtattaga tgaaaaagta gcaaatccta caaaaaatct ccctatcttg
     2941 gaagagttca aagactctgc aaaaatcaaa gaattaacaa agcaatacaa tcagttatca
     3001 tcagaattac aaaaagcaat ttctgaaatc aagtacacgc caagagcaag caataaaaat
     3061 ctgatccaat tgaatatgaa tgacggcaat caagttattg taaatatcaa taatcttgcg
     3121 aaccaaatga aatattattc gcaagtagcc aaagatatgg atgaaaaagg tgtgatcgac
     3181 atggaagttg gtatcttctc gcatccttac ggtagcactc aagaaacgga agaatcgggc
     3241 caatcggaag aaacaactga aagtgaagaa aatgcggatc aaacaaacga atcaagtgaa
     3301 gaggcagaaa cgcaaaaagc acaaacacct ggatcgtcta gcacaaacgg atcatctgat
     3361 tcaaatgatt caagtgaaac aagtcaaata gaagataatc caagtacaac tccgtcaagt
     3421 ttaaatgaaa attgataaaa caactttaaa aagtaagaat gtactttcta aaaaccagta
     3481 atttatggta gaattggaag cagtgaatat atctattaat aagtatattt taaaacggac
     3541 gctagttgtt cgcttgtata tggaatagta agtaggaggg aatcccattc atggcaaaaa
     3601 caggaatgta tgtaggcctt gatattggaa cgacatctgt taaagttgtc gtggctgaat
     3661 atatcgacag ccaaatgaat attattggag taggaaacgc aaaatcagaa gggattaacc
     3721 gaggcattat cgttgatatc gataaaacgg tccaagcgat acaacgagca gtacgacaag
     3781 cagaagaaaa agcaggtatc cagatcaaag gcgtaagtgt cggtttgcca gcaaacatgc
     3841 ttgaagtaga aaattgccag ggaatgattg cagttaacgg agattcaaag gaaatcaccg
     3901 atgaagatgt cagaaatgtg gcttcagctg cccttgttcg ttcaatacct cctgaacgtc
     3961 aaatcgtgtc aatattgcca caagatttta ctgtcgatgg gttcgaggga atcaaagatc
     4021 ctcgtggaat gatcggcgta agattagaaa tgtacggtct gttgtttaca ggacctaaaa
     4081 cgatcatcca taacatacgt aaatgcgtgg aaaatgccgg attaatcgtc aacgaaatgg
     4141 tgattactcc tttagcgctg actgaatcaa ttctttctga cggagaaaaa gattttggta
     4201 cgatcgtcat tgatatgggt ggcggccaaa caacaacggc tgttatgcat gataagcaat
     4261 tgaagtttac caatcttgac caagaaggtg gcgaatttgt cactaaagat atctctattg
     4321 tattaaatac gtcatttaac aatgcagaag cgttgaaaat aaactacggg gatgcatacc
     4381 cagaacggac atcaccagat gaagaatttc cagtagatgt gattggtcag tcagaaccag
     4441 tgaaagtcga tgaacgctac ttgtcagaaa ttatttcagc tcgaatggaa cagattttca
     4501 acaaagcaaa agatgcattg gaccaaatcg aagcattaga gttgccaggt ggcgtcgtat
     4561 tgacaggcgg agctgctagt cttcctggtg ttgtggactt ggcacaagaa atcttcggcg
     4621 taaatgtaaa attgtatgtt ccaaatcaca tggggctgag aaacccggta tttacaaatg
     4681 taataagtat cgtggattat tcagcaaact tgagtgaagt gtatcaattg gcaaaaattg
     4741 ctgttacggg tgaaacctca gcagctcgtc aaatggtagt tgaacaagaa acaacaaaca
     4801 catatgagag ctatgaagca cctgaagaaa caatctacga tgagccggaa ccaaaagagt
     4861 ccggagaaaa tgtaaaaaat aaaatcaagg gtttctttac aaatattttt gattaattca
     4921 tcctgggagg aataagatat ggaattctca attgataata atatcaatga cggcgcagta
     4981 atcaaagtca tcggagtcgg tggtggcggt ggaaatgctg taaaccgaat gattgaagaa
     5041 aacgttaaag gtgttgaatt cattacagcc aacacagacg tgcaagcatt aaaaaattca
     5101 aaagctgaaa cagttatcca attaggcccc aaatatactc gtggtttagg tgctggttct
     5161 cagccagaag ttggacaaaa agcggcagaa gaaagtgaac aatccttacg cgaagcttta
     5221 gacggtgcag atatgatttt catcactgca ggaatgggtg gaggaaccgg tacaggtgct
     5281 gcaccaatcg ttgcaggtat cgcgaaagaa ttgggcgcat tgactgttgg tgtcgtgaca
     5341 cgtccattca cttttgaagg accgaaacgt ggccgttttg ctgcagaagg tatcgctcgt
     5401 ttgaaagaaa atgtggatac attattaatt atctcaaata accgtttatt agaagttgta
     5461 gataaaaaga caccgatgct tgaagctttc cgtgaagcag ataatgtttt acgacaaggt
     5521 gtacaaggta tctctgattt gatcacagcg ccaggttacg ttaaccttga ctttgctgac
     5581 gtgaaaacag tgatggaaaa ccaaggtaca gcattgatgg ggatcggtgt ggctagtgga
     5641 gaagatcgcg tagtagaagc aacgaaaaaa gcaatctcct ctccattgct tgaaacatct
     5701 attgatggag ctgaacaagt acttcttaac atcacaggcg gtttggatat gacattgttc
     5761 gaagcacaag atgcttcaga tatcgtagca aatgcagcaa ctggcgatgt aaatatcatt
     5821 ctaggtacat ctatcaatga agaaatgggc gatgaaatcc gtgtgacggt catcgcaaca
     5881 ggtatcgatg aatcaaaaaa ggaacgcaag tctagccgac cagctagaca agcacaaatg
     5941 caatcacctg ctcaaaagac tgtattagat atggatcaag ctaaaccaac ttcttcagaa
     6001 gaagaaaaca gttttggcga ttgggatatc agacgtgaac aaaatgttcg tcctagagtt
     6061 gatgattcca attttgacaa tatcgaaaaa aaagaatttg atacattcaa ccgcgaagaa
     6121 acaaaatctc atggcgatga tgaattaaat acgccaccgt ttttccgtcg taaaaaataa
     6181 aggagaggaa gagcacatga ttgctgacaa cttgcagaaa atcaagcaag aaattcagga
     6241 ttcgtgtgct cttgttcatc gtgatccgaa agaagttaca ttagtagctg taacaaaatc
     6301 tgttgaatcc gctcaagctg aagaattggt tagagctggc gttatgaatt gtgcagaaaa
     6361 ccgagtagat aaattattag aaaagaaaca agatttattt gattttcctg aaataaagtg
     6421 gcatttaatt ggtaatttac agcgcagaaa ggtaaaattg attgtaaatg aaattgatta
     6481 ctttcatgcg ttggacagtt taagattagc agaagaaatc cagaagcggt tagagaaaga
     6541 attatcctgt tttattgaag taaatgtttc tggtgaggaa tcaaaacatg gaatttcacc
     6601 agatgagctt ttaccgtttg tggaatcttt agctgcctgc acaaaaatca aggttgttgg
     6661 gttgatgact atggcgccta aagaagcttc tgatgagcaa atccataaag tgtttggtac
     6721 gctgaaagaa ttgcgtgatc ttgttcaagc aaaaggttat gcccatgcac catgtagtga
     6781 attaagtatg gggatgagtc aagactttca aattgcgatt gaagaaggtg caacatttat
     6841 ccgtgtagga acagcgctat tcaaagacga ataaaggagg aacaaaaatg ccgcttttaa
     6901 acagaggagc aattgctaat tttttcggat tagctgatga ggaagagtac gaataccaag
     6961 attatcctga aacaacaaaa aaggctgtac agccaactaa aaaaaataca acacagaatc
     7021 aatcaactca ttctgtatct gctgcgaata ctcatgaaaa acaaaaaacg gcgacttcac
     7081 gtcctgtaac gcatgaaagt attcagccgg ctgaaaagaa aaaagtaatt gaactacatc
     7141 aatcacctac aaaaactgta gcgaaagaaa gaacagcttc aagaacctct acacaaccta
     7201 aagcaaatct tgctggaaaa atcactgtaa tggaaccaag agcttattct gaagctatgg
     7261 cgattgctaa acgaatcatt gctggagaag caaccttagt gaattttcat ttagtagaag
     7321 aaaaacaagc gagaagaatc gttgattttc taacaggaac agtttatgca ctagatggag
     7381 atatcaaacg tgttggagat gagatttttc tttgtacacc gactgggatg gagattgaca
     7441 gttcaaccgc tcaatctttt gcagatgcga atttgtttga tctgtaagag gaggaactac
     7501 gatttatact attgcactat tacttcattt acttcaacgg gcagcctatt tctatagcat
     7561 tatcttgatg gtatatgcat tgctctcttg gtttccaggc gggtatcaat cagggctagg
     7621 acgattatta gctaagatct gcgaaccgta tatcagtttg ttcgatcgtc tgcctttgag
     7681 gattggaccc ttggatttca caattttagg ggcaatcctg atcttgaact tagccgtaca
     7741 aggtttagca cagatcgtta tatggataac tgtccattta gtttattgat tgaagcaaca
     7801 aaatctttat tctcagaata gataggaggg gaaaattttg gatgcaaatg tataccagca
     7861 ctttcgggca gatgaacgta catttatcga ttcggtaggc gattggattg aacaggttca
     7921 aggacaatat gcaccctatc tgaccgaatt tcttgaccca agacaatcct atattttaga
     7981 aacactgatt cgacaaagca gtgatttgcg tttcatgttt tatggcggat atgaacaggc
     8041 agaaagaaaa agatgtttga ttttccccga ttattacgaa cctgtagagg aagattttga
     8101 aacagcattg tatgaaatcc attatcctag caaatttgcc agcctaagtc atgggaaaat
     8161 ccttggaact ttagtgggaa cggggatcaa acgctcttac tttggcgata tcatctcgga
     8221 cggtgatcgc tggcaagtat ttattgcaaa tgaggtggat cattttgttg ctgcacaagt
     8281 aacaaagatt ggaaaggttg ctgtacgctt ggaaccaatc aaatacacag aaatgattat
     8341 gccgaaagat agctggacac aagaaagagg aacagttagt tccatgcgac tagacagtgt
     8401 gatctctgag atttataata tttccagaca gcggtccaag cagctgatcg aagctggtaa
     8461 agtaaaagtg aactggacag aaaatacaag acctgatttt gtacttgaac tattagatat
     8521 tatttcagtc agaggttatg gcagagtcca gatccaagaa cttgagggga agacgaaaaa
     8581 agaaaagtac agggtactgt tcggtgtatt acgtaaataa aataaaaagg tggtttactc
     8641 atggctttaa ctccattaga tatccaaaat aagacattcc cgacaaaaat gcggggatat
     8701 aatcaagacg aagtagatga tttcttagat ttagttgttc gtgactatga ggaattgact
     8761 caaagaaatc gagaattaga aaaagcagtc aaacattctg aagaaaaact tgagtacttc
     8821 aatgaattaa aagatgcttt gaaccaatca atcatcgtag ctcaagatac ggctgataaa
     8881 gtaaaaacaa gtgcaagcaa ggaatccgaa gtgatcgtta cttctgcaca aaacaaagca
     8941 gatgagttag ttgcgaacgc tgaaaaacgt gcacatcaat taacaactga tgcagaagaa
     9001 aaagcaagaa aaatcttgac agatgcaaca gaaaaagcaa gacagcttgc gacagaaact
     9061 gaagatctta agaaaaaaac acgagtattc catcaacgta tcagcttgat gcttgagtct
     9121 caattagaac aagtgaaaag tccggaatgg gatgaaattt tacaaccatt ctccagctac
     9181 gtgactgaca gccatgaagt gatcaaagaa gttttagcaa aacagcttga caatgaaaat
     9241 gatactgatg taaactcaga cacaggagtc atagaagcac ctatgacggc atttgataca
     9301 caggctattg atatctcgat cgtgcctggt gaaaatgaaa acgagtagaa cagaaaagca
     9361 ctttgttatt cttaaagcga gccgatgaga gtggaagttc ggtaagacac tgcatggtga
     9421 aagatcctct acttgagacc tgcttttccg aaattagagt aagaagcagc ggctgacctc
     9481 gttattggtc acagagagtt tgcactagat agatgcaact aaatttgggt ggtaccacgg
     9541 catgttcgtc ccttgcggct gaacatgctt ttttgtgtcc ggaaaacaaa taaaggagtg
     9601 tatggttgaa tgaaaatgaa agaaaccttg caattaggaa aaacaaaatt ccctatgcgt
     9661 ggtaatttgc caaaccgaga aggcgagtgg caaaaagaat gggaagaaaa tcgaatctac
     9721 caaaaaagac aagagttgaa cgaaggaaaa cctagctttg ttcttcatga tggacctcca
     9781 tatgccaatg gtaatatcca tttaggacat tcattgaata aaatcagtaa agacattatc
     9841 attcgttcaa aatcaatgtc tggctatcgt gcaccatatg ttccaggatg ggatacacat
     9901 ggattgccga ttgaacaagt attggctaat aaaggcgtga aacgtaaaga aatgtccatg
     9961 gcagaatact tggaaaaatg tcgtgaatat gcactttccc aagtagataa gcaacgagca
    10021 gatttcaaac gcctaggagt tgcaggagat tgggaacatc cttatgttac attagatcct
    10081 tcttatgaag ctgcacaagt acgcgtattt ggtaaaatgg ctgaaaaagg ctatatttac
    10141 aaaggattga aaccaattta ctggtctccg tcaagtgagt cttctttagc ggaagctgaa
    10201 attgaatata aagatgtaaa atctccatct atttttgtag ctttcaatgt caaagacggc
    10261 aaagatattc ttgatgaaga tacagctttt gtcatttgga cgacaacacc atggacattg
    10321 ccagcaaacc aaggtattgc tgtaaatcca aaatttacgt atgtattggt ggaagccgat
    10381 ggccgtaagt ttgtcgtagc gaaagatttg ctagaaacag tccaatcaga aatcggttgg
    10441 gaaaatgtaa cagttctaaa agaatttgct ggacaagaaa tggaatatat gactgcaagt
    10501 catccattct atgaacgtga atcacttgtg attttaggcg atcatgttac tttagacgct
    10561 ggtactggat tagtccatac tgctccagga catggggaag atgactatat cgctggtagc
    10621 aaatataaac tatctgtagt gtcacctgta gactcaaaag gattgtttac agaagaagca
    10681 cctggatttg aaggtatctt ttatgacaaa gcaaatccta tgatcactga tctattaaaa
    10741 gaaaaaggag ctttgctgaa gctagatttc tttactcata gttatcctca cgattggcgg
    10801 acgaaaaagc ctgtgatcta tcgggcaact ccacaatggt ttgcatctat cgataaattc
    10861 cgtcagaata ttttggatga agtagaaaaa gtagagtggg ttatcccatg gggtaaaaca
    10921 cgtttgtata atatgatccg tgaccgcggc gattgggtaa tttcccgtca gcgtgcatgg
    10981 ggagtaccac ttccgatttt ctatgctgaa aatggagaag caatcatcac accagaaaca
    11041 atcgaacatg tggcaaaatt atttgctgaa catggatcaa ttatctggtt tgaaaaagaa
    11101 gcgaaagaac ttcttcctga aggatttacc cacccaggtt ctcctaatgg cgaatttaca
    11161 aaagaaaaag atatcatgga tgtctggttt gattctggtt cttctcatga agctgtttta
    11221 cgtcagcgac cagaattatc attcccagca gatatgtatt tagaaggatc agaccaatat
    11281 cgtggctggt tcaactcaag tatcacgact agtgtggcta tcaatggtgt agcaccatac
    11341 aaatcagtta tttctcaagg atttgcttta gatggtgaag gccgtaagat gagtaaatct
    11401 ttaggaaaca tcattgcacc agaaaaagtg atcaaacaat ttggtgcaga tatccttcgc
    11461 ttatgggtat ctagtgtaga ttatgaagca gatgttcgtg tttctatgga tatcttaagt
    11521 caagtggcag aagtatatcg taaaatcaga aatacgatgc gtttcttatt agcgaataca
    11581 gaagatttcg atcctaaaaa agatactgtt tcgtacaatg atttacgttc tgtagacaaa
    11641 tatatgaccg ttcgattgaa ccaagtaatc aaagaaatcc gagaagaagg gtacgacaaa
    11701 tataacttca tgcatattta ccgtacagtt atgaacttct tgacggttga tctatcgtca
    11761 ttctacctgg attttgctaa agatgtagtt tatattgaag cagaagatga ttatcaacgt
    11821 cgttgcatgc aaactgtttt ctatcaaaca gctgtagctt tgacaaaatt attgactcct
    11881 atcattccgc atacagcaga agaaatctgg tcattcctga aagaagaaga ggagtacgtt
    11941 cagttaagcg agtttcctgg ttatgaagag tttgcaaacc aagaagaatt gatggatacc
    12001 tggactgctt tcatggactt ccgtgataat gtcttaaaag cattggaaga agcaagaaac
    12061 agcaaattga ttggtaaatc tttggaagca aaactaactg tttatccaaa acaacaagtt
    12121 cgtgaaatgt taaaagcttt ggatgcagat attgcacaat tattgatcgt ttcaccagac
    12181 tactttgaag ttatggcagc agatgaacaa gtgccagata acgctatggt atttgatgat
    12241 gttgctatta cagtggaaaa agcagacggg gaaacttgcg atcgctgtcg ccaagttcgt
    12301 aaagatgtag gagtagatga aaaacttcct catctatgcg gtcgttgtgc aaaaatcgtt
    12361 gaagacttct atcctgaagc tgtagctgaa ggattcgaag aaaagtaaaa gggaaaaggg
    12421 ggtgtgacat gttctttgtc acaccccctt ttgttatcaa tcgtttaatt ttccacgttc
    12481 acgataccag ttatctggtt gccagatcca ttcgaatccg tctttttcaa gtagttcgaa
    12541 agctgcttta ggtcccattg atccagcttt gtagttggga aaatccggtt gtgtttggtc
    12601 ccaagctttt cgaatgacat ccacgatatg ccaagattga gcgacttctt cccaatgaga
    12661 gaagttcgtt ccatcaccat tcaacgcatc taatagtaat ttttcgtaag cttctgggct
    12721 attttcaacc atttctgcac tatttctaaa ttccaatttg attggttccg tttcaaatcc
    12781 ttgccctact tctttcccat tcaaggataa agaaaatcct tcagttggct gaatatagat
    12841 cgttagaaca ttaggtggaa gtgtcgtatc gtcacatggt tcatcgacag atgttttgaa
    12901 tacattaaca ggaacttgtt tgaatacgat gttgatccga gtcccttttt cagtcaaacg
    12961 tttgcctgta cgtacataga aaggaacacc tgaccaacgg aagttatcga tagtgaattt
    13021 gcctgcgacg aatgtttcag tctctgattg agcatccact ttgtcttctt cgcgatagcc
    13081 cttgaattgt acaccatcca attcaccttg agcatattgc ccgcgaacga agttttctaa
    13141 cacttcttct tcgttataaa tgcggatagc tttcaatgct ttgatctttt ctgtacggat
    13201 ttctttttcg gaaaatgcta ctggcggttc cattgcaagt aatgctacaa cctgtaaaat
    13261 atgattttgc accatgtctt taagtgcgcc actatgatcg tagtagcccc cgcgatcttc
    13321 tacaccgagg ttttcgccaa aagtaatttg gatattgtcg atatagcgat tgttccattg
    13381 agcctcaaaa atattattgg caaaacggat agctgagatg ttttggatca tttcttttcc
    13441 taaataatga tcaatcctga aaatatcttg ttctgggaat acttctctga tttgctggtt
    13501 caattcaaaa gcagactggt aatcagaacc gaacggtttt tctatgatca aacgattgaa
    13561 gccatttttt gtcataatat tttgtgattt caaatgagaa acgatcgttc caaaaaattg
    13621 aggtgccata gccaaataat agacacggtt accgtttaat tgatagtgtc catctaatcg
    13681 gtcagacaat tcttttaatg tctgataatg cgttgaatca tttacatcat gggattgata
    13741 gtaaaaatgg cttgcaaagg tagttgcttc ttcatctgaa ggattcaatg cacggattgt
    13801 ttctttgaca acttcacggt agtgctcatc gctccaggga cggcgagcgg ttccgattac
    13861 agcaaaatgc tcgcctaaat ttccttttct gtaaaggcgg aacaaagacg ggtacaattt
    13921 acgctgggct aggtcacctg taccgccgaa tatcgtaaac aatacatttt tttcattaga
    13981 catgtggata cactccttta tattttatcg acaaaaatcg tgctggccgc cttaaagctg
    14041 acggggattt tctttctatc attttggata gtgatcggtc cttcataagc tgcgatgtca
    14101 acgatctcat attcttcgtt gatattcagg tcaatagtga ctaagtaatc caacaattct
    14161 ttttcatcaa gcactcgtgc gatacgcact tttgtaccga caggatagga ctccaatgtt
    14221 tgtcggcgtt cttcatggac aacttcctct tttttaggaa tcgatcctcc atgaggacaa
    14281 tgttcaggat gattcaaata gttttctaaa tgatctgcaa gatgttccga agtcacatgt
    14341 tccaatactt cagcatcatc atggacttca ttccagctat agtctaaatg ttcaactaaa
    14401 aaaacttccc ataagcgatg tttgcgaatc agactgctag ctttttgcag tccgcttgca
    14461 gtcaattgta caccttgata aggggaatgt tctacaagct cttctttcac aagtttagaa
    14521 atcatttcac tgacagatgc agctgagaca tctagactag atacgatttg tttattgttg
    14581 actttcgttg tatctccacc tagttctaaa atgattttca aataatcttc tcgatttggt
    14641 gtcatattcg atcatccttt catggtaaaa aaccatcatt agtaagtgta acaaaaaaaa
    14701 cgttaattga ctatttttct aaataaaaaa caaaggattt ttagacgttt ttacaacaaa
    14761 aaacgaaaga tgatagagaa gactcattct ttcgtttata aaggatatat atatacattg
    14821 ggagggatct atttttcaga taacaactta tatgaagtgt ctgcagattc gtcataaaga
    14881 gtttgttcgg gataagaaaa gataagataa aaaccatact gatcacgtac gactaaacga
    14941 tattcatcta tttctaccac agatgtgcca agagactgac cgttgatcaa aaacgtgtaa
    15001 tcagatgtaa tctgtaattg ttgtttttgc tggctatcac taaagaacca tgtaccttga
    15061 tactttgaga gtccttctga cttttccgct tgttttttct ttttcaagta aataaaactt
    15121 gagagaacgg taatgagtga accaagaaaa tagatcattt tttttatcac caaatcactc
    15181 ctttatgaga aaataatcgc atagacatat tctttcttct ttatttcatt gtaccgaata
    15241 aaagctaaaa tttctctaag actttcgact ggttttttta ctgtttttct acaaattatg
    15301 ataggataca tagtaggaag aaaggtgaca taatttgaag tatcagcaag tggaaatagc
    15361 tttttttatt gaccgcccga atcggtttat agcacattgt atgaaaaaag acggagaaat
    15421 aattattgcg catgtcaaaa atacaggtag aggaaaagag gtcctgatac caggcgctga
    15481 agtggctatt gtatttgctc ctggacctaa acggaaaacc gcctatgatc tgattgctgt
    15541 aaaaaagaag ggtgactggt ttaatatcga tagtcaattg cctaatcggc tggcaattga
    15601 tggtatttta gacggcacga tccttttacc aggattaact ggtccattta cggtatacaa
    15661 gcgtgaagta acttatcttc actccaaatt tgatatttat ttagagacgg tggtcggaca
    15721 aaaagcattt gttgaagtca aaggtatgac acttgaaaat aaagcgattg gtgcttttcc
    15781 tgatgcgccc acactcagag gattgaaaca tataggagaa ttaacgtatg ccgcacaaga
    15841 tggttatgcc gcttatgtct tgtttattgc tcagttcgaa catcttcatc tggcaacgat
    15901 ccatgaagaa atgcaaccag cactagctga tatggttcga catgcgcagc aaagcggagt
    15961 tcaaatcctc gcctataatt gtcaagtatc ggcagatgag gtaactgtca agcaggccat
    16021 tccatttgat gtagatatcc cttttgaaga tcctatacaa tagaaagaag gtaaaataat
    16081 gatcaactta ggtattatcg gaacaaattg gattactcat caatttgtcc aagcagcttt
    16141 aagcacaaaa aaatatgaat tgacagcggt atattctaga catttggaaa aagcacagga
    16201 atttggttct cattatgaag gggatatcga attcgcaaca gatttgaaga cttttttcaa
    16261 tattactcat atggacacca tttatattgc ttctccgaat agtcttcact ttagtcaagc
    16321 taagcaagca attttggcag gaaaaaatgt gatagttgaa aagccagctt tttcgacgcc
    16381 aaaagaaatg gatgaaatca tccatttggc aaatgaacac aatgtgtatt tttttgaagc
    16441 agcaagaaat atccatgaat caggttttaa aaagattgcc gattacttac cattaaaaga
    16501 cgagataatc ggtgcaaatt tcagctatat gaaatattct tcgcgctatg accaagtatt
    16561 agatggagaa gaaccgaata tcttctcgac tcatttctca ggtggtgcat tgatggattt
    16621 aggtgtttac cttgtatatg cagctgttgc ttggtttgga atgccaaaag aagtccatta
    16681 tttcccaaga aagatttcta ctggtgtaga tggtcttgga tgggggatct tacgttatga
    16741 gaattttgat gtatcgatcc agccaggtaa aatcggtgat tcttatttac cgtcagagat
    16801 ttattttgac tcaggaacgc tagtgatgaa tggagtcaat gcaattgaac aagcacaatt
    16861 tcatgatcgc gcgcataaag aaatcattga tttggcggta acagctgcag aaaatccaat
    16921 ggcagatgaa gcagaggatt ttgccaatgt catggctcat ccgaaagatc cagcttgggg
    16981 attgttgtat gaagagtgga tcgagctagc tagaaatgtg aaccaagtga tttatgattt
    17041 aagaaaaaat ggcggcatca aattcgatgc agataatgag gaagattttt aatgaacgaa
    17101 tttgtacaag tatttcccga aaattggcag aaaaaatatg aggataaagg gtttatctca
    17161 ccttctctta ttcaacgagc agtttttcag ccactaagta ataaacaaag tatagtagcg
    17221 gtttctccta caggttcagg taaaacactg gcttatcttt ggcctctact actaaacgtg
    17281 gaaccaggtg aagcaagtgc gttggtcatt tttgcttctt ctcaagaact agctattcaa
    17341 gtagcagatg ttgcacgtga atggggaaaa gacaaagagt tgaaagtcca atctttggtg
    17401 ggcggagcca acgtcaaacg tcagattgag ggtttgaagg aaaaaccaga aatcttgatt
    17461 ggtacaccag gaagaatatt ggaattgatg aaagcaaaaa aaataaaagc acatcaagtg
    17521 aaaacaatgg tatttgatga agcagaccag ctatttgacg ctgggaacag ccaaatcatt
    17581 gatcaaattc ttcatcaagc tccaacagag tatcagctag cttttttttc agcgacagca
    17641 gatcgttccc ttgaaagcat tgaaaaaatc actgggaaaa cgtttgagac aattgacgtg
    17701 acagcagagg acgattctcg aaaaggactg agacattact ttttacgtgt accgatacga
    17761 aagaaagatg actacttgag acgtctcacg catatagaag attttcatgg tctgattttc
    17821 tttaatcaac tgactgaatt aggcgtaatg gaagaaaaat tgctgtatag aggtgtaccg
    17881 gtaggaagtc tggcctctga tcagaacaag ctactccgaa aagcagcgct agaacaattc
    17941 aaaaagaaaa tggtcagagc acttttgacc acagatgtgg cggctagagg tttagatatt
    18001 acaggtcttc cttatgtagt gaatgcagaa gttccgttaa gtgaagaagc ttatttgcat
    18061 cgttcgggaa gaactggtcg aatgggtaat gaaggaatag taattacact cgtacaagat
    18121 aataatctaa gagatttaaa acggctttta cgtccatcaa atataacact tgaagagatt
    18181 tttttatacg gaggtaagct gcaaactgag cagccaacca aagaagatgc agctcctgca
    18241 gtaaataaaa agtatgcgaa aactttttct ggaaaggagc agaacccaga atataacaaa
    18301 gaaaaaataa gaaaaaaagt taaaaataaa tcaaaaaaag agagaaataa aggagcaagg
    18361 cgcaaataag cgccttttta tgctatgatt atgaaaacgg gaacaaaatt ggttgccaga
    18421 ggaggggtta tgtgaaagaa cgtcaagaag agatcttgca gctattgaca gaaaaccaac
    18481 aaggattgac agcaagtgat gtagctgagc gcttaactat cgatcgaagc aatgcaagcc
    18541 gatatttaag tgaactatac aaggcccatc atattgtaaa aaccgctggc cgaccagtcg
    18601 tttactcttt gccaacggaa aagtcaaaat ctgatgaagt gcatgtcgac tcttctacgc
    18661 aagtgacttt tgaaacactc gttggagaaa atgattcttt aaaagtcagc atacagcagg
    18721 caaaagctgc gattctttat ccaccgcggg ggttgcatac gattattttt ggagaaactg
    18781 gtacagggaa gtcgatgttt gctgaatgta tgtatcattt tgcaatcgat tcagagatgc
    18841 tttctgcaga tgcgccattt gtttctttca attgtgcgga ttatgctcaa aatccgcaac
    18901 tgctctttgg acacatcttt gggatcaaaa aaggggctta cacaggagca gctcaagata
    18961 gtcccggtct aatagccaaa gcagacggcg gtatattgtt tttagatgag atccaccgtt
    19021 taccgccgga agggcaggaa atgctgttta ctttcattga taaaggtatt taccgtccgc
    19081 ttggagaaag tgcacaagta catgaagcat ctgttcagat cattggggcg acgactgaat
    19141 cttcagaaag tttcttatct acgttcaatc gacggattcc tatggcaatc accttgccga
    19201 atcttgcttc acgttcactg gatgagcgtt atgaaatcat ctctcttttt atcaaacaag
    19261 aagcgaatcg tttgaatcaa cgtatcgata tcgaaaaaga agcgattctt gccttcatgc
    19321 tttatgatgc ggaaggaaat atcggtcaag tgaaacgaga cttgaaacta gtctgtgcaa
    19381 aatctttttt acattaccgt actcatcatg agaaaaagct aatcattcga aaagaagaac
    19441 tttcccttca agtacaaaaa ggattactga aaatcaagga aataccggaa cgtctcgacc
    19501 gattcatgga cagcaaaagt cagtatttga catttgaacc aggatttgct gatgttgtct
    19561 ggtcacaaga tccagaacga aacatgcagg tctataacga tattgaggaa aaagtcactt
    19621 ctctttccga aaccggtgtg gagaacattg atctagagac cctcatttca aaagatgtgg
    19681 atgcttattt ccagacatat gtcaaagaat tgactaaaag ttcgattccc aaagatcttt
    19741 tgccagatga aatctggcgg ttaaccaatc aattgtatga tgtggctgaa aaacggttag
    19801 accgtattta taatgaaaaa gctcgttttg cttttgcttt gcatctgcaa agtacattgg
    19861 atcgtgtgag agaaggtcat atgatcgtcc acccagattt gaataacgta cggaaaaatt
    19921 ttaagaggga attccaggta gcaatcgatc tttcaacgat cattgaagaa gaagaacaag
    19981 ttgagattcc ttttgatgaa atcggcttta ttagtatgtt tctttctatc aatctaggag
    20041 aaagtgagcc tgttaaagaa aacaaagtag atgttctcat attgatgcac ggcagacaga
    20101 ctgcttcaag catgttggag atggcacaag aactattagg aacaaaagta gggaaagctt
    20161 ttaatatgcc actggttatg gaagttcaaa caatgtatga agaagtgtta caatatgtca
    20221 aaaactatca agagcatttg acgaatggcc tactcttgtt aacagatatg ggatcattaa
    20281 acaccttcag tgatttgatt tatgaagaga ctggcattcg gacgaaagct atcacgatga
    20341 caagtaccat gattgtgata gaagcgatac ggatggcaag tgttggaaga agcttagaag
    20401 atatttatca aaatatccag ctttcctttg aatcgatcgt acgtgatcag ttcaaagcgg
    20461 aaaagtctga aactttacag cgtaaaaaag ccgtaatcgt gacatgcttt actggtgaag
    20521 gagtagctgc caaattatat cagcgtatta tgccagtgat taatcaaaat aaggtagaac
    20581 tgatccagat gcagttttta gaacgtgaat cattcaaaaa acacatcgat gccttattgg
    20641 aagaatatga gatcaaagca attgcgggaa cagttgatgt tgattatcaa aatatcccat
    20701 ttttttcagc ctatgacgtt tttgatgatg aaaaactaaa tattttaaag cgtatagctg
    20761 atgatgagat cccgacagct aaaattgtcg attcacttgc tggatcatta agcgatgtct
    20821 tttctattga tgaactgatc cgttcattgc aaaagacagt tcagcagatc cagaccgatt
    20881 tgtcgattat cgtggaacct ggagtagata ctggaatcgt tatccattta gccttcatgt
    20941 tagacggatt gatcaaacaa gaaagccatc ggcaatttga gaaactgtct attttctcaa
    21001 aaatttatcg tttggaaatg gatatcgttc gggcaaactt gatggcacta gaacgaaaat
    21061 atcaggtaaa aattccagaa gatgatatcg catttcttac acaaatgttt cttgaaaata
    21121 aaataaaaaa atgaacacac taatcatact gtttacacac taaacatctg tgtgcgcact
    21181 ataaaaaaga gctaaaaagc atgaaaacgc tatttcagct ctttttttta ttggcatgct
    21241 tcttgcgtta tataaaagtg taaaaaaata aaaggagtgt taaaaatggc aaaaaaaaca
    21301 atcatgttag tttgttcagc agggatgagt acgagtttat tggtcacaaa aatgcaaaaa
    21361 gcagcagaag aaaaagggat ggaagccgat atttttgcgg tctctgcctc agatgcagat
    21421 aataatttag aatctaagaa tgtcgatgta ttattattag gtcctcaagt acgtttcatg
    21481 aaagctcaat ttgaacaaaa acttgcgcct aaaggtattc cattagatgt catcaatatg
    21541 caagactatg gcatgatgaa cggagaaaaa gttcttgcac aagcagaaaa tctaatgaaa
    21601 taaatcaagt atgcagttgg gggtataaca acgtggaaga tcaacaaaat ctagaagcca
    21661 tcatggggtt aatcatgttt ggcggtaatg caaagagcga tgcaatggaa gcgattgcgg
    21721 ctgctaaaat cggtgatttt gagttagcgg ataggaaaat cgctgatgca gaagaatcac
    21781 ttatacaagc gcatcatgca caaacagaca tgttgacaca agaagcacaa ggaaatcata
    21841 tgcaagtgac attattgact gttcacagtc aagatcactt aatgacatct attgcgttta
    21901 ctgatttagc aaaagaaatc atcgaacttt atcgtcgcgt atacagcgaa taaatacaac
    21961 ttcttttttg aacggaagaa gaaaaatttt tgaacggatt ttttattttg ttataaggag
    22021 aactctcttt atataaaaaa cttataggag gaagtaaaaa atgaacggac tatcaagttg
    22081 gatggagaaa tacatcctgc cggttgccgc aaaaatcgga gcgcaaaaac atttagttgc
    22141 tttgcgtgat gcttttatcg gcatactgcc cgcaacaatg gcgggatcag tcgctgtaat
    22201 gatcaatgca attattcgtg atttaccgca acagtttaac agtacctatg ctgacagttt
    22261 agcagcagac aaaggaatct ttgccgtatt gaatgtcatc atcggaatca atggttttgt
    22321 ctggaacggt acactagcaa tcgccggatt gatctttgcc ttttcttggg ggtataatct
    22381 tgcccgagct tatggagtaa atgatctagc tggggggatc gttggtttag ctaccttgat
    22441 tcaaggtatt tcctttggtc cagcattatc agcagcatta gatgtgaatg ttccttcaaa
    22501 tgtcgcagat gcaatcaata gttctgagat tggtgcaacg attgcagatg gcacactgtc
    22561 agttggatta tggggttggc taaaactaga tcatttgaat ggaaacgctt attttacagt
    22621 tatgatcatg ggagctattt cagtcattat tttttgtaaa ttgatgcttg ccaacattac
    22681 gatcaaaatg cctgattcag taccaccagc agtatctaaa gcatttgcag ccattttacc
    22741 agcgacgatc gctttatacg tcattgctat tatcaattat atcgtaggtc gtgtagctga
    22801 tgggcaactg atcattgatt tggtgcaaaa atatattgca gaaccattcc tagggttatc
    22861 tcaagggttg ggagcagtat tgatcgtcac agtatttgtt caagtattct ggttctttgg
    22921 tattcatgga tcaaatgtat tggcaccagt gctagaggga atctggggac aagcacaact
    22981 aatcaatatt gatattttcc aaaaaggtta taacggaaaa actggtacac cagccgtgtt
    23041 agatgcaatc gaagatggaa aagcttatat gtgggtccgc ggatcgttcg atgcttttgc
    23101 atggtttggc ggatcaggcg gaacgatcgt cttactgata gctatcttga ttttctctaa
    23161 acgtgcagat tatctaacag tagctaaatt atccattggg cctggtatct tcaatatcaa
    23221 cgaaccagtg atgtttggtc tgccaatcgt attgaatgca atcatgttta tcccattctt
    23281 gattgctcca gtagtagcaa cagcaattgg atggacagct acttatcttg gcctagtcgc
    23341 tccggtatcg cagcaagtca catgggtagt accgccgttc ttattgtcat tcttagcaac
    23401 aggagcggat tggcgggcac cgatcgtaac attagtatgt atggtcgtga ctttcttgat
    23461 ttgggcacca tttgtcatct ctgcaaacaa aatggaccct gccgcaggcg aacaacaata
    23521 agatgaacgt gaggagcggg acgctttaag tttcgttcct cataatgaat tttcgaggag
    23581 gaactgaaat gattacaatt gccagtgcaa tgcaacaaga tgaaatcaaa gaattgttag
    23641 aaggatacaa tgaagaagga atgactttta catttaaaga aaaacaagga atcaagctgt
    23701 tctttgaaac aagtgcagaa gatccggaag ttgcggctaa aaaagcaaag gaactaatca
    23761 aagcacagcc ttggggaaca gtcctttatt ttcaatcaac agctgtttag aaaatggttt
    23821 aaaaagatag gatggttgag atgataaaaa acggtttatt tttatgtagt attggttctt
    23881 tgatcgtgtt gtatagtttg aatccacatt cgcaaaggta tgatttgtat agtatggtca
    23941 caggtctttt tctaacagga ttaggaatct atttcttcat gaaggggaaa aaaagagaag
    24001 aagcaaagga gaaaaataac taatggaaat cacgaaaaaa ttaaatattc cagcatcgtt
    24061 tttttacgat aaagttatgg actctgtcct tttcgatgta cgtaaagcga ccggcaaatc
    24121 agtaactaga aaacagctga aaaatttgga gtacgtcaaa caattctcgc aaaataaccg
    24181 ggctcgcata aaaatcgaag aagtcattga aaaccagtct tataagtttc gtacatcgac
    24241 aacgaagaat gaattcgtcg ttcattatca aatcaaacca ttggacgatt cgacctgtga
    24301 ggttcattac acagaaaaaa tggagtctta tggcatgctt caaaagttga atgatatgct
    24361 tttaggaaca atcttgatgt attttaaacg gagacgtttc aaaaaaatgc tagatatgat
    24421 cgaagcaacg tattaaatca atgaaacatg gtactattta gttattgaaa aatgaagtaa
    24481 gctagaagga atttttcata ggaagataga tctttcctgc gaatcctcac tagctttttt
    24541 gtaggaaggg gcagcaaaat gacaaacaaa gtaagagagc taggtgtatc ttcgattgag
    24601 gaaatgtttg atttagccac ttatgcattt aatggggcag atacacctga aaggcgagaa
    24661 cgttttcgta cacttgcgga gaattcttgg aattacggat tttttgatga ggaggatcgg
    24721 ctaacaagtc aagtcatggc gacccctttt ccagtgaatt tttacggaca agagtaccta
    24781 atggccggca ttggctatgt tgcttcttat ccagaagcaa ggggacaagg cgggatcaat
    24841 cagatcatgg aaaagatcct tgaagattgc cgtgatcgta aagtaagctt atcttatctg
    24901 gcgccattct cctatccctt ctatcggcgc tatggctatg aacaatcatt tgataaaatc
    24961 agttatcaac taaacagtcg tgatgtgccg tttatcaaaa aaaaatctgg aaaaataaag
    25021 cgtatggatt ttgaagatgc aaaagctgca atcagaagaa tttatgaaca gatgccggaa
    25081 aaccaacgag ctggtctgaa gcgcgaagac tggtggtata cgtataaatt caagcaaaaa
    25141 ggcaattacc agtttgcttt gcattttgat gataatgagg aagcaacggg atatatcgtt
    25201 tatcagcttg caacgtcttc ctttattatt gcggagtggg gatttttgga tcatgatgct
    25261 ttttgcagcc ttgttcgctt cgtaagttct cacaatggtg cttttgaaac atttgaatat
    25321 tcatgcggct acggcggtaa tgatcaaaat tatctattag aaaatccatt tgcttctgta
    25381 atgatcacac cttatatgat ggcgaggatc gtagatattt ctttgttttt ggaaaattat
    25441 ccatttaaaa agagacaagc tgcatttgcc ctacaaatag aagaagatca ttatgcgaaa
    25501 tggaatgaag gaatcgtgga agtaacaatc gaaaatggaa aaaatcatct ctcaaaagta
    25561 gaacaaacaa aactcccaat cgttcgagga agtatccaac atatcacgca gctattatta
    25621 gggtatcgta aagtggaaga gttggtattc caagaaagaa tacaggtgac aaaagaatat
    25681 gaagaaacgt taagctcaat cttgccacag caacagccaa ttcttaatga ctatttttga
    25741 taaaaaacgg gtgatgacaa tatttttgtc accacccttt tgtttttcat ttggcatttg
    25801 aaggaaaatg ttaaagtaaa tcctcttttt tcgtaaattt gaattttttg ttttcttttg
    25861 ttttagggtt ttcttttttg tggtcttgga ttgcttcttt cgtaatcttt tcccgatttt
    25921 ttttagatga atctaagcgt tctgcgtata ctttttcttt tggcttatca ttcattggaa
    25981 aggacctccc tacattattt cattctacct ctagtttatc atctgttaag gactagtgga
    26041 aacgttttgc ctaacttata agctgatttt tttagcagat aagcttgcaa gtaaaaaaca
    26101 aacaagctac aattgattta ttgaaattgt tcctgtagct cagtaggata gagcaatcgc
    26161 ctcctaagcg ataggtcgct ggttcaattc cagtcaggaa cgtataaata acccctgtat
    26221 cctttgcggt acaggggttt gttttgtatt tgtgccaaaa atgtgccaaa ctagttatca
    26281 tttttatata aactatcgaa cacagtattg attttttctt tatcctgatc ttcaagctct
    26341 cgaacaatat gaagataagt agacattgta gtttctaaac tgctatgtcc taaacgtttc
    26401 gatacgctaa gtatatttac tccttgataa agtaaaatag atgcatgtgt atgccttagt
    26461 ccatgcaaag taaattgctt ttcaatccct aattctttta attttttgcg caaatatttg
    26521 ctgacggcgt ttgatgaaac taatccattt tttaagttga aaaaaacaaa attatgaggg
    26581 tttttgattt caaaattctc gaataattct ttttgattga ttttaaactt ttttaagaga
    26641 tcaatcgtat gtttatcaat ggaaattttc ctatttgaag tttcgttttt tgtttttccc
    26701 cattcattta atttataatt ccatgtttta ttaatagtga tgatttgatc ttcgaaatcg
    26761 atatcttccc atgttaatcc tagaagttca gcaaatcgca ttccagtggc accagcaact
    26821 aacacgagca taggagaaga gtactgcgca gaaaggtttt cttctacgag tttcattaaa
    26881 gatttaaatt gatcataatc taaatattta tcttcttttg gcttcaatga atcttttcct
    26941 ttgattactg cttttctagt tggatcaaac ggaattaatc cttcttctac ggcatctttc
    27001 aacgacgctc taatatggtt attaaactta ataacggtag attttacatg gtctttagca
    27061 tacttattta aaaagcgttg atatcccact ctatctaaat cagaaatcaa taccgctggc
    27121 atatatttct ttatgttcat taacgtatct tcgtattttc tataagtgat aggagatact
    27181 gttccttctt tataaagttg catccaatcc tcaaagtaat ctgataataa tagatttttg
    27241 cgatcccctt taaggccttt gttcaagtta tattctaatt cgttggcggc atcttttgct
    27301 tctccttttg tcttaaatcc tgattttctt atcttcgtgt attttccgtc atcttttttg
    27361 tatgaaattt cgtattgcca actatttcca cgtttgacta atcttgccat aattgaatca
    27421 gctctctttc tctgatacaa taggaactat aaagaagccc attgtttggg ttttattatt
    27481 ttttgcacat cctttttgct tgccggcgca aggatgtgct atttgtcgtt ttaatggtat
    27541 aattggatgt gtattagatc atccaatcag aggtgtttat tatgattaaa gtgattttta
    27601 aaagaataac tgaacttcca gagtttagat tatttgttga ttattggtat gtctggtttt
    27661 ttattgttgc attgctgata ggtctagatg tcatattaga aagaaaactt aagtaagagt
    27721 tgagttaata aattgaattc ctaaatgaga tattttgtag cccatatttt gtttgccgac
    27781 atcacctaat actatggagc taatcgtttt ttctaacaga ccaaaatcag ataatctatt
    27841 taagctacca tctattagct cttgtgaata gccagacatg ctgatatttc cagtgaaatt
    27901 ttcgtttcca cgactcatta agcatgctaa caattgaatc tcaatcgatg ttaattgatt
    27961 cagtacaaga agataatact cctcgttatc ccatgaagcg ttgttaattc gaagtaaaca
    28021 attcttataa agatttttat acatatctat tttattttgt gcctttgatt tttctacctc
    28081 gtcatttatc ccttcgaata ttccaatgag ttggtccttg ttctctaagt tgaaaacatc
    28141 ttctggaatt tgatcgcgaa tgttttctaa tgattcgttt aaatttttgt agaatttctc
    28201 gatgcgtttg aaacgcttct cgtttttaga cccaaaataa agtgactgca caacgccacc
    28261 aatataagga attgctccaa taccgccttc aactattaat tcaagatatt cttttttggt
    28321 tagtttttca ttgctattat ccatagttac ctcctatttt gtcatttcct ttacaagcat
    28381 tgtgactcct gatggcactc ttttgtatag gttttattat tgtgcacaat ctaactctta
    28441 gtggggcgtg gttcatttat tttttactta ctttactatt aatcatatcc cattgagcat
    28501 aggatttttc tatgttcgat cctcttgaac taatttctcc tgtaaaagtt actttatcgc
    28561 cctttgtaaa ggtatcagca ttgtttaagt ccttcgcaaa aattacatat gaaactttag
    28621 gtgttgcaga aatatcattc caacttttat catcgtactc tttgtctgct ataatggcta
    28681 ttctagtagt cattgattcg ataacagttc cttcaaaagt atatgtttta ccactaatat
    28741 atttagtaaa agctgtattt tgctcagtag ctggagtaat agaataataa ctatctaaga
    28801 aagcacccca gtcatgatta tttgtctcta aaaattcttc aaattgagtt aggcttttat
    28861 tgctgctgtt agatgtagta gtttgagtat cagatgatga gctttcctgt ttgttattgt
    28921 catttgcctc gtttgatgag gaaagcgaga aacctacggt agtaaaaata atcccgataa
    28981 taaggagaat cataggtgtt ttcttatttg tttttttgat aaatcttaca attaacatga
    29041 ttaaacctat aataaataaa acaataccag taaaaccaaa tataccgtcc attaatagat
    29101 cctctttctc ttttgatatt gaatattata aaccaagcaa ttcttttttc ttaaaatcga
    29161 attcttcttg attaataatc ccttcatcta acaactcttt atacttttta atttcatctg
    29221 cacttgaaat ttgtgtttct ttggaattat tatctaatat agattgttgc ttctctatat
    29281 atttttttaa attttccatt tcattccaat atttttttgt aaacataacg gtgttttcat
    29341 ctttcgtggc cgctaatata cctccgcgac tttcgtttcc gcctagcaag gtaaattgta
    29401 tataaccatt actcatacct ggttttttta attgtacggc tgatatattt ttaaagggga
    29461 tagttttttc tcctttaata ccttgattaa ctaaatttat aaatcctttt ctaataattg
    29521 aaatagaatc atcagttact ttaatcaagg tttttcctgg agattttatt aaaatctctt
    29581 tttccatttt ttcttcctca tttctgtgat atgatttttt ttgtagaagc tcatatatga
//
LOCUS       DADGKS010000030        27893 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.030, whole genome shotgun sequence.
ACCESSION   DADGKS010000030 DADGKS010000000
VERSION     DADGKS010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27893
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.030"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(343..2313)
                     /locus_tag="JXV47_001444"
     CDS             complement(343..2313)
                     /locus_tag="JXV47_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487495.1"
                     /translation="MEIMGRSQLLNFKKKRKTKKEQKTRNSKVVNNTFVSDLTSLVGY
                     QFTPSYIRTGKRWGTIVKLVNTYGMNRNYGFGWMVKAIPEVRVEGVKAYLIEADKPVS
                     QKDQQEIMHENVGGSTNSYENNLEGKNSDAEISKTVMRIMDLNTASLLDSMANKIIDW
                     KLEILLVSDSPNKISEQLIKLQRLYDEKMYGLKLMSYGGDQRDLFDRLLSEPIGNVYE
                     YTSMSSDFAGNDHAIRKGLDDANGWAIGTMSTSYASGVAFMALDDSFTSKVLVASHKN
                     ATIKGYDEKISASSLWGQLIANNAMANHKRTFHIVLNKFDYFGDPTGRTFVAKPSLNS
                     VIEKVNLAEEGLNSLELFGNQKDIGDLYRRNLDKLTQIFYLLAGRTLDSATRVLLKKE
                     LGNFYISQKLWDINYEERSKLLVNSSDTMPVLGDFISYLTNAETKAKKSGTEKEVDRI
                     IVLKDTLRTALDSFSRMFNQRTTLKEIGKSDKLQFYYNLGDLRAETNVMEAQFLNTFD
                     FITSQAKKDDIVMIHGFDKLSIETVGLIKKRLTMLEEDGIRLAFLFDTIGSGEDNEYK
                     EDIETADIFNTDGKIYQSFESDFNYTIIGKMTSGELMKYEKKVAPARKGEDDQKLSVD
                     LRQYLTTGRSNKFQIRRPVDLTNNFVIGEFIL"
     gene            complement(2328..3194)
                     /locus_tag="JXV47_001445"
     CDS             complement(2328..3194)
                     /locus_tag="JXV47_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487496.1"
                     /translation="MADNSNYGFKHNLHQKPSETIVRVEWLEKHVNSTYSVTAKRLIV
                     SAIVVAVVVLGSIVYLVSDTIKLKFIFVPTLLMIIGFLILISQYMFIDPSSGSLISGS
                     IRLFKSVVNSARVSMGKKKPFRGTEILKVKQDGTIVYRDGSVALMFNLDGATSLTAFP
                     EEVMAQESKSIQYQNTRDRSLAEIKITSSQPQNTERQTRNMKIQKRNARSNKAVFDII
                     DQQERFVSEYIDGVKTTVIQYLILKSQSKMVLDEGVERLENYTSRGLYYSVTQLSAKQ
                     TKEILSDIYALK"
     gene            complement(3184..3417)
                     /locus_tag="JXV47_001446"
     CDS             complement(3184..3417)
                     /locus_tag="JXV47_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAX1487497.1"
                     /translation="MREEKIVYPVIQNNQENMTSSQHLQEAQLVYQVNELPQTNETMS
                     KSISLIGLLIVAIVITVGVYRKLNVKGSISDGR"
     gene            complement(3429..5591)
                     /locus_tag="JXV47_001447"
     CDS             complement(3429..5591)
                     /locus_tag="JXV47_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487498.1"
                     /translation="MAKFKDITESINYVAETVPVVALSLKPQLLEVYQKEEKEAKAKK
                     AKVKVWKEFDALLTKDLPKKNYMVIEDVQKLNSEEVIDEDDAILDSEKYVVLLKSSLN
                     YVADLPEKFKEKLLAGVRFMDSSGQLLLIPDDPNMFESEVEEATDFYSAVEQLEVATN
                     GLERLAETFNSSEEVEFEALAEDIPDEKEALFADDDKPTEAENQEVSIEETQTQIQTE
                     TYQQSKIDEKPESQSDKENYVYEVEKIVSESDVPKSLDADFLEKNFEQIIADKFQPVV
                     LDEINDPVDLNEEMLSIAELKPLLFLAKESMNARISIANNKINSELNKTKEQLILKGK
                     QMLADELLRIEQATSLNGQNQFTNTLSVAKESYEAEASKIDDLVMEKSSIIRKDYDMA
                     KQAYLDAELKKLEQRYDAEHLPEVKQQEDEYRKATEESLDQQYQEAIESIKNDALKQN
                     QEAKEVVVERIINSLKPEIENSLTDVQEKTLEIVEKTKSENEAEFHDTKEKITDVVVK
                     YFANKEEVEKQVANNTKELETKLVEQQKTIEEYKDRMKEVKDLAEGYRSNSEKLAEQS
                     EALREDLSRSRSDLAQMAEKTKSLAVATENQSSSKRDFTSKKMATIISVAAMACGTIL
                     GSSYFISHNNQQAQAQTQTSISRVENSIGTNTNSASTNSSYEATPTTEFKVGKDVVIS
                     IDGKTTKAEVISIDGEKAVVKTPDGNQYKIQAHLSDNN"
     gene            complement(5591..5833)
                     /locus_tag="JXV47_001448"
     CDS             complement(5591..5833)
                     /locus_tag="JXV47_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487499.1"
                     /translation="MVFDREKMLAHANEVLMSGLKGTELAKIMNMNVNQFYDYRNGSK
                     KIEKARLETLIKFEKAYVYMLDKQKRTIDRKKGVLQ"
     gene            complement(5943..6281)
                     /locus_tag="JXV47_001449"
     CDS             complement(5943..6281)
                     /locus_tag="JXV47_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487500.1"
                     /translation="MFDSIKNLVSGMTPDMKTLVQVVLYFLAFVFSLKPGFTAMKFFG
                     DAKWGDGLKYVGAIIAIFIIPVITTVMLYTMGTKTGNDLNQKANIISALIPVVGIYLV
                     SKFPKNEQLG"
     gene            complement(6680..10321)
                     /locus_tag="JXV47_001450"
     CDS             complement(6680..10321)
                     /locus_tag="JXV47_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487501.1"
                     /translation="MKFKKYLLQNLRIKRWVVRGLVIGGVLAVTLGAPFGMNDPTPDN
                     QDSKQETVINKNVAYAESKPAEQGMWTLYARILMGDKEVNDSAAKTGQMNLLGQGGIS
                     ADFPYSDISKQGNSIAGGNAGTQLASTLATYSYYGYIETVSGNAIASQASSILGSIGR
                     TIGSFIGSISLILSNIAESINELLGKFFMSMNIFSLMGWGEGGSDVSNPVSKALTSLL
                     NNLGLNNELFKAIASLSMLFFTAILGYQGMKLLSKDGVNSKGLSPVLEKWIVRIFVLF
                     IFLPVAGSLLGVYINGIQSAKKDGDIPTNVVSDYIINTRLWASTQNLAPSSDTGGDVP
                     DGKPTSEIKFVDTDYEPSKKSAMIRAINTSSYARQNNDLDSNSVGMALLKEWSSNDTF
                     NINTYAGDVNVAENDAYMGRAPAVWTGYNLGDGKEGSAIKKPTNLNGYIWSANQNVTD
                     DNRKPDGKGTAHNFDATQPWGVANNATFSTQSVALLLQSALDTSGAKFYAYNIAPSGI
                     QGSAKNMSTVKTEWRTASLVGHGAMGKFGSWLAMNAESIVLAVLYLACAWAMFNVNIV
                     KAFKREFIRIWEVVLTGSLASGAGVMAISLGVVTTSLIGLQLPIFLITFIRAFGDTAV
                     GFIPNTLVGDGVANIVRSAMILGVGYLLVFKKGEKVNNLINMLIGLPLEVAFGFDERA
                     KLLFGNRNDAVRVVDGVSKAIKKSQGAKNPYYDGGNSSVKDMVAGGLGAVGAQKMAER
                     LNNMGDSNADAKSIADKVIPETPEGMSFNGGGVGSTINNTSFKDLVRQDQLRNNSQQY
                     IDHLGRMVDENGNFVDENGEILKDSKYGKDAKGNFIDEKGRLIDEDGNLIDTNGKPLE
                     DSEDGNIGMDSEGRLIDEKGRLVDEDGNLVDENGRRLLNGDFGQDSNGRLVDEKGRLV
                     DEDGNLVDEFGNKLGKHSDGYNVNGDLVDENGNIIETRDALVADRNRELEQQRHTPIA
                     VAIPENEDDEITLDQTHQELRNEMSGEDVSDRVHRELGNGASGESQSRELNSNFDNSA
                     IRNDTALKDRESLSKETDKEQSDVKKKFIPTPNINQTDKYETNNGLGMSKDNQSIREP
                     ELTNDNNRTNNSKSTSDNSGKSNQSTKKPSTAKSAVEYLSKTGKNVYTSADKALAKSP
                     KGSLAGITYEAKNEAIKIGKGTAKVAKATATGASKTGKVVKKSTMSVKDYIVKYGNQK
                     STENKSEDE"
     gene            complement(10324..12273)
                     /locus_tag="JXV47_001451"
     CDS             complement(10324..12273)
                     /locus_tag="JXV47_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HAX1487502.1"
                     /translation="MENSTEFFKNIQTEFNHALTPMKPPKHKLVGRDDELHELSLILN
                     RPETPQAILLGEAGTGKTALASEWAERQRQDGKKVQVYKLSIGQLRVGGDDVLQTRLE
                     TLIPRLKEYERILKAEDKDNEFVLFIDEFHKVVSSFGSGNKIGGDSLKEPLANESLQM
                     ITATTRKEYENYIKRDDALGRRLQPLELNELKSDVVVDILRQWLNTSSVKDDPQASFR
                     LSQRIPDELLQEIVQANKLYREDLSEPAKSIAVMEDLIAKDRVDGNAYNRESLLQIFG
                     KYNIQLDSDFDMEKLQEELKSIKGQPLAVYTITMLFKRMKLGFDRFKGRKQPKATALF
                     TGSTGVGKTAMAKAVARGLYGDENKVLLVNMPDYKTKDDAMRFRRLIGTHVRHDPSAI
                     IVCDEYEKAGVETLDAFLSILDEGRISFTERGWDDREVHDTVSLSNTILFATTNAGAE
                     MFDSLNRYSSLSRVTNKENSNEYSTELKREYRKVASGIKQALIGEGLKPEVINRFGRI
                     VPFWALSEQTLLEIAYNEMLKSAELVRKHLNIDLRLPPKKERVYGQNFYADDLSMHLV
                     FDMASQEDSKSGGARNILHLVESEFEEAITEAIITYPNAKIFDVKLSEAGAFEGKGDS
                     NAEIIAKPSVAESKENKIVFSIGGA"
     gene            complement(12315..13373)
                     /locus_tag="JXV47_001452"
     CDS             complement(12315..13373)
                     /locus_tag="JXV47_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliS"
                     /protein_id="HAX1487503.1"
                     /translation="MEKNVNSTSTKDQYSIIGGLLGDKDKRTRHGLRIMLATFLGVLF
                     LLTGLGSYIYQLGNYNYYLVNNTTPIGSSLEFARSGAEITISDVWTDQNRDVTVVKLG
                     YSQNARKLLSTQGKNYNLYMATKEKDRPKKLEMSYGMLSTDGDAFLFLKGKLEERAYQ
                     VFIANQVSLISGDDTADDDTKVNVNEADSVTKALSQYSMNDVNNEGVISFGKKAKPVN
                     TPDNINFRINPYSDSTNVYQGSFLTKDGDIDYSKVVAVTSKNNVVNKLEDQLNASNTN
                     IKKIEATKAEYLERLQQNPDDKDSQESIRQLDSRMETEIKAINDTQKLIDQYKNADFN
                     KDSFGDMKTTFKYLTLTD"
     gene            complement(13491..13946)
                     /locus_tag="JXV47_001453"
     CDS             complement(13491..13946)
                     /locus_tag="JXV47_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487504.1"
                     /translation="MNAINWHEFVNYMESLLDDLKSFSIADAVKHGLPVSTTMKLRGL
                     KIPDEIIKLRTKTIIETAKVVDNMNHELKGKKTTYEKDFERFLKSVIGKYLGKKSFSE
                     LRDEEIVPTPMVSKIRKNKAEGNYYLGTIAKIIDYLENKEQKKGTKKGR"
     gene            complement(14530..15333)
                     /locus_tag="JXV47_001454"
     CDS             complement(14530..15333)
                     /locus_tag="JXV47_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAX1487505.1"
                     /translation="MSQEVTEKIIDSDVDLVSEQTNAIVRYNNGLNTTALRGFKPVEM
                     DVFWAILSKMKRQGTAEVTFDFNLFRYLVKYDRREKDSFYSVLKALSDKLGTLTYRFE
                     DSDVYEQLWLFQKFRIDKQKETVTIKANEEFEFILNSIGKNFTRFELDNFTKLRSSYT
                     KELYRHLMQYRNKEWRNGYWVVKVEDFRRALSIPSSYRMTNIDKRILEQAKEEFLAPD
                     ENGIQVFETFDYEKIYAKKGRRVDRLRFTFSEPESNLPTISMHNWLEED"
     gene            16313..17536
                     /locus_tag="JXV47_001455"
     CDS             16313..17536
                     /locus_tag="JXV47_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HAX1487506.1"
                     /translation="MESYQFQIFKLVPSLERRGNRMKITEKNVNPKFEPTESNLKKFD
                     LTVTLSNELVDSIVEMDAMPQKIYLYAIGHLDPKNPPFNNTVKVSKKALFALMSSSSS
                     SSKHSRLKQVIEKLHQQSVIKIQRTKPNGKTEYKVISPLEITEFNDFSDAVSIKFSSS
                     IMPLLTNLEDHFTQYAFDQVVNLTSKYAISFFQLFTKDFNLYLANRDNLTWSTKSLDR
                     LKNPVFSIADLRKKFSIEKKYKAFRDFERRVIKEPIAQLNKYTDFKIDYELIKKGHTY
                     TNIKFLLTRTMSVPVPYKQEQRDPAYLKGAEDKTEKMNQSYLKAMNSKYTKLLIKNFL
                     ISSADLCDLKLMSRLQNKVYPLYDRLSKDRGFESVVNHLSYVATHKEDYTIKNTVKYL
                     EKSITSYLPYVNLYD"
     gene            17571..18338
                     /locus_tag="JXV47_001456"
     CDS             17571..18338
                     /locus_tag="JXV47_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAX1487507.1"
                     /translation="MKKDELTKYNEEFLATIDMKMDLKSYELYQLLFSYISPTKLKKT
                     GVVDLPVKAIINYMDVDQNLETELKTIVNTLQRQAVYEISNLDKKYKTYTTVSAIDRI
                     HWDLEEHSVSFSFSEDVIPLIVSIKKKYPFFVFEDLASFQKKYSIVLYKYLAMYYKKY
                     LIAKNKGDFEKAEIYKNPLIEIVKIREITKTENEYKTISNFDRRVLRESVEEINEKSM
                     LNIDFAKVRKGRNYNFAVQFNISSEFDEKTYREKKLG"
     gene            18530..18928
                     /locus_tag="JXV47_001457"
     CDS             18530..18928
                     /locus_tag="JXV47_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin HicB"
                     /protein_id="HAX1487508.1"
                     /translation="MKYFFCAVFEWKGNEYAVKFPDFPDLYTHGETLEDAFEMAQEVL
                     EGYLVLLELQEKEIPSPTPVQELNARIKRSENVNLFVVKANTKVAKARNKQNYDRKSV
                     TVEHYLNVLAAEENINLSKALNDLLREKLI"
     gene            complement(19235..19630)
                     /locus_tag="JXV47_001458"
     CDS             complement(19235..19630)
                     /locus_tag="JXV47_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487509.1"
                     /translation="MKQEKRKMKQTQTETVNDTLADQLAGYYKLFEMGKAQRLIHYLW
                     KYKILFLFWESTLTFSVLFYKSDFYNQHLVLGSFLLIYTILMLNLYTYITLEEHLVIS
                     DAGIERNIKRVSFKITLNKPTDKKLSEAF"
     gene            complement(19631..20008)
                     /locus_tag="JXV47_001459"
     CDS             complement(19631..20008)
                     /locus_tag="JXV47_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487510.1"
                     /translation="MKSKKETEPMKATHLNYFSRTLINNLLKDTTGISVSTKHFANDL
                     IIFEDNNLRIEMFIEQATPNSIPEFCYTHTEKMKHAKSVKDVEALSESLTNALNLVKK
                     AKLLFEFQTDYHNELLAQSEILD"
     gene            complement(19998..20393)
                     /locus_tag="JXV47_001460"
     CDS             complement(19998..20393)
                     /locus_tag="JXV47_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin HicB"
                     /protein_id="HAX1487511.1"
                     /translation="MKTKNIFYPAIFEKEGEAYNIVFPDLPEISTFGNSLEEAYLNAK
                     DALGLALYSVPDAEFPKPSAVEELTLKANQVVVIIQLNIKLFRRSLNTKTIRKNVSVP
                     EWLVLLGKEKNINFSQLLQKALEEELLEK"
     gene            complement(20460..20645)
                     /locus_tag="JXV47_001461"
     CDS             complement(20460..20645)
                     /locus_tag="JXV47_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HAX1487512.1"
                     /translation="MPKTAREIVKILKSNGFKKTGQTGSHAKFYNSKTKRTVVVPIHN
                     GDVPLGTEANIWKQAGL"
     gene            complement(20727..20981)
                     /locus_tag="JXV47_001462"
     CDS             complement(20727..20981)
                     /locus_tag="JXV47_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487513.1"
                     /translation="MNYTDEEQITLEYVFIDEEGEEIEKVLIISSKDLENALTYEPYE
                     STVTVNEFLDTYTSDDTWEIMNICNANNIQFAEKTNKSFY"
     gene            complement(21003..21248)
                     /locus_tag="JXV47_001463"
     CDS             complement(21003..21248)
                     /locus_tag="JXV47_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487514.1"
                     /translation="MWTLEGKTFAEIWTEFIEVPTRIDPITSEKVLDADFYNLKAGTS
                     LECVWMYLEEHFKGVTLGHVLYHNGAEWDAIGNIHFS"
     gene            complement(21255..21539)
                     /locus_tag="JXV47_001464"
     CDS             complement(21255..21539)
                     /locus_tag="JXV47_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487515.1"
                     /translation="MLTATLQQPTHVAIAESYTINAGIVKQLIKDREFKKFNSRQVYN
                     RQLKKAILKHKDSFIGNLESVDVKTVSTAFSVVEVTIDGRLISLFAFGIN"
     gene            complement(21642..21824)
                     /locus_tag="JXV47_001465"
     CDS             complement(21642..21824)
                     /locus_tag="JXV47_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HAX1487516.1"
                     /translation="MINLFLLVTASTLFFTGISLIISYLIYKKAENHTSKATGLAVSS
                     FLTLLTLFVTLSFSFV"
     gene            complement(22030..22569)
                     /locus_tag="JXV47_001466"
     CDS             complement(22030..22569)
                     /locus_tag="JXV47_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487517.1"
                     /translation="MYNISVNKLINFQKERFFMGWYGDYSSANEVIEEKKGYAKNGLE
                     IVDTKVTKIYGIILFKDAEGTYDIDSFIFRDEMYKPIYFLNDSPAYFKKIPKKWLKFF
                     VGDQEKMVKRQLDRIKEESNKPKLDDLLVAGKTYSIWDGSYVAVYQYKLKRSFIFRLQ
                     DGSLTRFTRLSAGDVKEVA"
     gene            complement(22682..22948)
                     /locus_tag="JXV47_001467"
     CDS             complement(22682..22948)
                     /locus_tag="JXV47_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAX1487518.1"
                     /translation="MTYQVRYEREAQKALKKMDKFQAKVILNWIEKNLVGTDDPRKHG
                     KGLTANKSGYWRYRVGAYRIIADISEHEVTILILSIGHRSEVYK"
     gene            complement(22950..23171)
                     /locus_tag="JXV47_001468"
     CDS             complement(22950..23171)
                     /locus_tag="JXV47_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HAX1487519.1"
                     /translation="MPVISIRVSKEEKDFLEKVAEFNGDNISEFMRSNSLQTAETLVD
                     FATYKQLMKEHEENDQSISHEDMLKELGL"
     gene            23397..24215
                     /locus_tag="JXV47_001469"
     CDS             23397..24215
                     /locus_tag="JXV47_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAX1487520.1"
                     /translation="MEKKLSIITGNIEKGGTGKTTTIYNLGGYAVENLGMKVLYIDED
                     KSQNLSKRFPDAFSKAKRENTINHLYLHGSAEPLAINENMDILVAGEDLKQVEMQMRD
                     MPNNRTLLFRWIVVNYEQLKEKYDLILIDTHNDAGLLAQNAWAVSDLVVGISDPSKDG
                     FEALLKLGKDIDALAKQLIDIKTGETLMETKYATIGSRIKHNTNSSREFLELVPTLSN
                     YLGYVQEKELLNATSLEGKNIAEFAKDKNIYRKNKDFFESTFTLYNKIIDTAQE"
     gene            24219..24515
                     /locus_tag="JXV47_001470"
     CDS             24219..24515
                     /locus_tag="JXV47_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487521.1"
                     /translation="MIEVKENRFKKFAEAEVEEVPEVVEAVEEPKQTPKETTSSLVAK
                     LKSDSSEKKKNYQFTLQPSQRKKLSKISEKLGIRSDSALLGEMIDNLYDEVFGE"
     gene            complement(24697..25050)
                     /locus_tag="JXV47_001471"
     CDS             complement(24697..25050)
                     /locus_tag="JXV47_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487522.1"
                     /translation="MNKGKSERYVVIINREKVSELPLAEFLESEYETLGVKYSQTIKK
                     ALNLYRRVKNNEVTIIEAGNDRNDSKVAEVKKKPTDHNPIQQEHPSTVTSDHSAKKEK
                     PMLKGFNAPSNKDLL"
     gene            complement(25070..26125)
                     /locus_tag="JXV47_001472"
     CDS             complement(25070..26125)
                     /locus_tag="JXV47_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParM/StbA family protein"
                     /protein_id="HAX1487523.1"
                     /translation="MKEPLLFSVDLGNKSVKEMSTHVSPLSLPSRILNKNIINSGRFS
                     NIGSSLKRSLNVSEYSLVNTTESYYFGKDIHELGKDDYVIESLGFGISRYKQETYKNI
                     LSFSLANLARLEDQSDDVLTVNLVLGLPSSDYTETIVKYVMQQATRQHSVEVDGKAYN
                     INVDTVWVLPQPIGTLYNLLLADDGSVQDETLISQKIGFVDIGGGTKLFDVVQNFEID
                     ENNREQKDTGIFTLYNRIVNMLDLPISPNAFQLEKIIREGKEKGVYLFKPSGNESFDI
                     SEVVEREIKTYTNMVVAEVLATFKNFTTLDKVVFTGGGASIIDKQLVKDKIPHTLFVE
                     DSEFSNVKGFYKFGLTQ"
     gene            26341..26739
                     /locus_tag="JXV47_001473"
     CDS             26341..26739
                     /locus_tag="JXV47_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487524.1"
                     /translation="MRLRRNKNYTTIILEDFTDQELLIVGKTKADFIEKGNASIVKAS
                     KVAVEKYFDSLEESAKEIFNGEKAGSYELDGIRFSLIPTTENIIPKKLYYIFSSEKHT
                     SMKPCIFDWQWLIDAVLDVKCSKYNITLGC"
BASE COUNT         8628 a         5016 c         4253 g         9996 t
ORIGIN      
        1 aaaactctcg ctttttcttc atcagtaaag tttttataca actgattaca ataatgaggt
       61 ttttgaagtt tctgaatacc tatactaact tcaaatcctt cttcatgttg aattaggatt
      121 acttctgtgt ctctacctag aaatattcga tctaaaattt ttatgtttgg tttcattatt
      181 taacctccac tataattatt tcactcagta aggtttcact ttatgaaatt tctatagttc
      241 tcttttcaca aaacgtacca tgttctctaa gactgttttt agtctcaaat atacatgttt
      301 tttcttatcc tttccttata cactcaaaat caaagataaa acttaaagaa taaactctcc
      361 aataacaaaa ttattagtca gatccactgg tctcctgatc tgaaatttat tacttcttcc
      421 tgttgtcaaa tactgtctca aatcaacaga aagtttttga tcatcttctc cttttctagc
      481 aggagcaact tttttttcat acttcattaa ctctccactg gtcatctttc caatgatagt
      541 gtaattaaaa tcactttcaa aactttggta aatttttcca tctgtattga atatatcagc
      601 tgtttcaata tcttctttgt attcattgtc ttctcctgaa ccgattgtat caaatagaaa
      661 ggcaagacga attccatctt cttcaagcat tgttaatctt tttttaatta gcccaacggt
      721 ttcaatagat aacttatcga agccgtgaat cataacaata tcatcttttt ttgcttgtga
      781 tgtgatgaaa tcaaaggtat ttaaaaattg agcttccata acattggttt ctgctcttag
      841 atcacctaag ttatagtaaa actgtaattt gtcactttta ccgatttctt tcagtgtcgt
      901 tctttgatta aacatcctag agaagctgtc taatgctgtt ctcaatgtgt cttttaatac
      961 aataatacga tcgacttctt tttcagtacc agattttttg gcttttgttt cagcattagt
     1021 caaatagcta ataaaatccc caagaactgg cattgtatca ctactgttca ccaaaagttt
     1081 tgaacgttct tcataattaa tatcccaaag tttctgactt atataaaagt tacctaattc
     1141 ttttttcaat aaaactctag ttgcagaatc taatgttctg cctgctaaca aataaaaaat
     1201 ctgagttagt ttatcgagat tccgtctata taaatcacca atgtcctttt gattaccaaa
     1261 aagctccaaa gagttaagac cttcttcagc caaattaacc ttttctatta cactgtttaa
     1321 cgaaggtttg gcaacaaatg ttctaccagt tggatcacca aagtaatcaa atttatttaa
     1381 gacaatatga aaagttcgtt tatgatttgc cattgcatta ttagcaatca attgccccca
     1441 aagtgatgat gctgagattt tttcatcata gcctttaatt gtagcgtttt tgtgtgatgc
     1501 cactaaaact ttacttgtaa aagaatcatc cagtgccata aaagctacac cacttgcgta
     1561 gctagtagac atagtgccga tagcccatcc attcgcatca tctaaacctt tgcgaattgc
     1621 atgatcattt cctgcaaaat ccgaactcat agacgtatac tcatagacat tcccgattgg
     1681 ttcacttaaa agtctatcaa acagatcacg ttgatctcct ccatatgaca taagctttaa
     1741 tccatacatt ttttcatcat acaaccgttg gagtttaatt agctgttcgc tgattttatt
     1801 aggagaatcg gatactaata ggatttctag cttccaatca ataattttat ttgccatgct
     1861 gtctagtaaa gatgctgtat tcaaatccat aatccgcata acagttttgc taatttcagc
     1921 atctgaattt tttccttcta aattattttc ataactattc gttgatcccc caacattctc
     1981 gtgcattatt tcttgttgat ctttttgtga cactggctta tctgcttcaa ttagataggc
     2041 ttttacccct tctactctca cttcaggaat agctttaacc atccaaccaa atccataatt
     2101 tctattcatt ccataagtat tcactaattt cacaattgtt ccccaccgct tacctgtcct
     2161 aatgtaagat ggtgtaaatt gataaccaac taaagatgtt aaatcactaa caaaggtatt
     2221 attcactacc tttgaatttc tagttttttg ttctttttta gtttttctct tttttttgaa
     2281 atttaatagt tgtgatctac ccataatttc catttaatct ctcacctcta tttcagtgca
     2341 taaatatcag ataatatttc ttttgtttgt ttagctgaca actgagtgac actataataa
     2401 agtcctctac tcgtatagtt ttctaaacgt tccacacctt catccaatac catcttagat
     2461 tgagatttca agataagata ttggattact gttgttttca caccatcaat atattctgat
     2521 acaaatcgtt cttgctgatc tattatgtca aagactgctt tgttactcct tgcatttcgt
     2581 ttttgtattt tcatatttcg agtttgtctt tccgtattct gaggttgaga tgaagtgatt
     2641 ttgatttcag ctaaggaacg atctctggta ttttgatatt gtattgattt cgattcctga
     2701 gccataactt cttctggaaa agcggttagt gatgtagccc catctagatt gaacattaat
     2761 gctacactcc catctcgata tacgattgtt ccatcttgtt tcacttttaa aatctctgtg
     2821 cctcgaaatg gtttcttttt ccccatagat actcttgctg aattaactac tgatttgaac
     2881 agtctaatag aaccagaaat caatgaacca ctagatggat caataaacat atactggcta
     2941 attagaataa gaaatccaat tatcattaat aacgttggaa caaaaataaa tttcagttta
     3001 atcgtatcag aaactaagta aacaattgat ccaagaacaa cgactgcaac aactatagct
     3061 gatacaatta atctttttgc tgtaacagaa taggtgctat tgacatgctt ttcaagccat
     3121 tcaactctga caattgtttc agaaggtttt tgatgtaagt tatgtttaaa tccatagttt
     3181 gagttatctg ccatcagaaa tacttccttt cacgttcaac ttacggtaaa cacctacagt
     3241 tatcactatt gcaacaataa gcaagccaat taaagatatt gacttgctca ttgtctcgtt
     3301 cgtttgtggt agttcattta cctgatacac gagctgtgct tcctgtaagt gctgagaaga
     3361 ggtcatgttt tcttgattgt tttgaattac tggataaact attttttctt ctcgcataat
     3421 agccctcctt agttattatc agataagtga gcttgaattt tgtactgatt tccgtctgga
     3481 gttttcacaa ctgctttttc tccatcaata gaaatcactt cagccttagt tgttttccca
     3541 tcaatactga tgacaacatc tttcccaact ttgaactctg tagttggtgt tgcttcatag
     3601 ctactatttg ttgaagcaga gttcgtattt gtcccaatcg aattttccac tctcgaaata
     3661 gatgtttgag tttgagcctg tgcttgttga ttattatgac taataaagta ggacgatccc
     3721 aagatcgttc cgcaagccat tgcagcgaca gaaatgatag tagccatctt tttacttgta
     3781 aaatcacgtt ttgaacttga ttgattttct gtagcaactg ctaatgattt cgttttttct
     3841 gccatttgag ctagatcact tcgggaacga gataagtctt ctcttaaagc ttcactttgt
     3901 tctgccaact tttcgctatt tgatctataa ccctctgcta aatctttgac ctctttcatt
     3961 cgatctttat attcttcgat agttttttgt tgctctacaa gttttgtttc taattctttc
     4021 gtgttgttag ctacttgctt ttcaacttct tctttgttcg caaaatattt gacaaccaca
     4081 tctgttattt tctcttttgt atcatggaac tcagcttcat tttctgactt tgttttttca
     4141 acaatctcta acgttttttc ttgcacatct gttaatgagt tttcaatttc tggtttcaat
     4201 gaattgataa tccgttccac cacaacttct tttgcttctt ggttttgttt caatgcatcg
     4261 tttttaatag attcaattgc ttcttggtac tgttgatcaa gactttcttc agttgctttt
     4321 ctatattcat cttcttgttg tttaacttct ggtaaatgtt cagcatcata ccgttgctct
     4381 agtttcttta gttcagcatc caaataagcc tgtttcgcca tatcataatc tttacgaatg
     4441 atactggatt tttccatcac taaatcatca atcttagatg cttctgcttc gtagctctct
     4501 ttagcaaccg ataatgtatt tgtaaactga ttttgaccat ttaatgaggt tgcttgctct
     4561 atccgcaaaa gctcatcggc taacatttgc tttcctttga ggatcaattg ctccttcgtc
     4621 ttatttaatt cactgttgat tttattatta gcgatagaaa tacgagcatt catactctct
     4681 ttagctaaaa acagcaatgg tttcaactca gctatggata gcatctcctc gtttaaatca
     4741 acaggatcat taatctcgtc taaaactaca ggttgaaatt tatcagcgat gatctgttca
     4801 aaattttttt ctaaaaaatc agcatctaag cttttcggta catcactttc ggatacgatt
     4861 ttttctactt cataaacata attttcttta tcactctggg attcgggttt ttcatcaatt
     4921 tttgattgtt ggtaggtttc tgtttgtatt tgagtttgtg tttcttctat gcttacttct
     4981 tgattttctg cttcggttgg tttgtcatca tctgcaaaaa gagcttcttt ttcatctggt
     5041 atgtcttctg ctaaggcttc aaattcaact tcttcagaag agttgaaggt ctcagcaagt
     5101 cgttctaatc catttgtagc tacctctaat tgctccactg cgctatagaa gtctgtagct
     5161 tcttcaactt ctgattcaaa catattagga tcatccggaa taagtaataa ttgaccacta
     5221 ctatccataa aacggacacc tgctaatagc ttctctttaa atttttctgg tagatcagct
     5281 acataattca aacttgactt caatagaacg acatactttt cggaatcgag aatagcatca
     5341 tcctcatcta taacttcctc actgttgagc ttttgtacat cttcaattac catataattt
     5401 ttctttggta aatctttggt cagcaacgca tcgaattctt tccatacctt taccttagct
     5461 ttttttgcct tcgcttcttt ttcttctttt tggtacactt cgagtaattg tggcttcaaa
     5521 gagagtgcaa ctacaggaac tgtttctgcc acataattaa tagattcggt aatatctttg
     5581 aattttgcca ttattgtaaa actccttttt ttcggtcaat agttcttttc tgtttgtcta
     5641 gcatatatac atatgctttt tcgaatttaa taagcgtttc aagtctggct ttttcaatct
     5701 ttttactccc attccgataa tcatagaact ggttaacatt catattcatt atctttgcca
     5761 gttcggtacc tttcagaccg ctcattaata cttcgttggc gtgagctaac attttttctc
     5821 tatcaaaaac catcttacat ttactttctt ccctcacttc taaactacgc ttggagcgta
     5881 gttttgtggt aaaaagtaaa ttgaacaaat cggcatatta tccaaatttg ttcaattcac
     5941 ttttaaccta actgttcatt ttttggaaat tttgaaacta gatagatacc aacaactgga
     6001 ataagtgctg atataatatt agctttttgg ttcaaatcat tacctgtttt agtacccatt
     6061 gtgtaaagca taacggttgt aattacaggg ataataaaga ttgcaataat cgccccaaca
     6121 tattttaatc catctcccca ttttgcatca ccaaaaaatt tcattgcagt gaatcctggt
     6181 ttcaacgaaa aaacgaatgc caagaaatac aaaacaactt gtactaaagt tttcatatca
     6241 ggcgtcattc cgctaaccaa atttttaata gaatcgaaca tataaaaacc tcctttttaa
     6301 tatttttaat aagttaatta tatcatcgac aaatcttatt tgttcacttg tcaatgatct
     6361 aactaagaaa aagacgtctc gatatttaca tctttatgtt atcataataa cataaatttt
     6421 tgatgattaa aagagatttt ccattaaatt atttcatttt ttttattggc taaaaatgct
     6481 ggtttatcaa gtttttgttt agataataat tctgttcttt accagcataa gcccttttta
     6541 attaaacaac tttgaacagt aaatatttaa ttcatttata gataatttta aaaatttttt
     6601 tgcataaata gaaatttttc ttgacatctt cagttaaaaa taaaagtaaa aagaaggagc
     6661 aaatcaatgc tccttctttt tattcgtctt cagacttatt ttcagttgat ttctgattac
     6721 cgtattttac aatatagtcc ttgactgaca tggtagattt cttcactact ttaccagtct
     6781 tggatgctcc tgtagcagta gccttggcaa ccttagccgt tcctttacct attttaatag
     6841 cttcgttttt agcttcatag gttatccctg ctagactacc ttttggagat tttgctaaag
     6901 ctttatctgc tgaggtgtaa acatttttac cagttttcga tagatattca acggctgatt
     6961 tggctgttga tggtttcttg gttgattgat tagatttccc tgaattatct gaagtagatt
     7021 tagaattatt tgttctatta ttatcatttg tcagttcagg ttctctaatt gattgattgt
     7081 ctttcgacat tcctaatcca ttatttgttt catatttatc tgtttgatta atattaggag
     7141 taggaatgaa ctttttcttc acatctgatt gttctttatc cgtttctttc gatagcgatt
     7201 ctctgtcttt aagtgctgtg tcattccgaa tagcactatt atcaaagtta ctgttaagct
     7261 ctcttgactg actttcacca gatgctccat ttcctaattc ccgatgcact ctgtctgaca
     7321 catcctcacc actcatttca tttcttagtt cttgatgagt ttgatctaat gtaatctcgt
     7381 catcttcatt ctcaggaatt gcaacagcaa ttggcgtatg ccgttgttgt tcgagttctc
     7441 tatttcgatc tgccacaagc gcatctctcg tctcaatgat attcccattc tcatcgacta
     7501 aatcgccatt cacattatat ccatcgctgt gtttaccaag tttattacca aactcatcaa
     7561 caagatttcc atcttcatca actaaacgcc ctttttcgtc aactaaacgt ccgttactat
     7621 cctgaccaaa atcaccattt agcaacctgc gtccattttc gtcaacaaga tttccatctt
     7681 catcaactaa gcgacctttt tcatcaatta aacgtccttc gctatccata ccaatattac
     7741 catcttcact atcttccaat ggtttaccat tagtatctat aaggtttcca tcttcatcga
     7801 tcaaacgccc tttttcgtca ataaagttgc ctttagcatc tttaccgtat ttactatctt
     7861 ttaatatttc accattttca tcgacaaagt ttccgttttc atcaaccata cgtcctaaat
     7921 gatcaatata ttgttgggag ttattacgta gttgatcttg acgaactaaa tctttgaaag
     7981 aggtattatt gattgttgaa ccaactccgc caccgttgaa tgacattcct tctggtgttt
     8041 caggaattac tttatcagca atggacttag catcagcatt gctatctccc atattgttca
     8101 aacgttcagc cattttttgc gctccaactg ctccaagacc tcctgcaacc atatctttta
     8161 ctgagctgtt gccaccatca taatagggat ttttagctcc ttggcttttc ttgattgctt
     8221 tagaaacgcc gtccacaact cgcacagcat catttctatt accaaataat aacttagcac
     8281 gttcatcaaa cccaaacgct acttcaagtg gtaagccaat aagcatatta atcaaattat
     8341 ttactttttc gcctttttta aaaactaaaa gatatcctac acctaaaatc atagcagatc
     8401 gaacaatatt tgctacgcca tcgccaacta atgtattagg aatgaatccc acagcagtat
     8461 caccaaatgc acgaataaaa gtaatcagaa agataggtaa ttgtagtccg atcagagatg
     8521 ttgtaacaac acctaatgaa attgccatca cacctgctcc tgatgcaagt gatcctgtta
     8581 gaactacttc ccaaatccga ataaattcac gtttaaatgc tttcacgata ttcacattga
     8641 acatcgccca agcacatgct aagtaaagaa ctgctaaaac gattgattca gcgttcatcg
     8701 ctagccacga gccaaactta cccatcgctc catgaccaac taaggatgct gtacgccatt
     8761 ctgtttttac tgttgacata ttcttagcac tgccttgaat tcctgaagga gcgatattat
     8821 acgcataaaa cttagctcct gatgtatcaa gtgccgattg gagcaataaa gctaccgact
     8881 gtgtgctaaa agttgcattg ttagcaacgc cccaaggttg agtagcatca aagttatgcg
     8941 ctgttccttt tccatcaggc ttgcgattgt cgtctgtcac attttgattt gctgaccaaa
     9001 tatatccatt taaattggtt ggtttcttaa ttgcacttcc ttcttttcca tcccctaaat
     9061 tatagcctgt ccaaacagca ggcgctcttc ccatataagc atcattttcg gcgacattaa
     9121 catcaccggc ataagtatta atattgaaag tatcattcga tgaccattct tttaatagag
     9181 ccataccgac tgaattagaa tctagatcat tattttgtct ggcataactg ctagtattga
     9241 tcgctcttat cattgcagat tttttagatg gttcataatc tgtatcaacg aacttgattt
     9301 cggatgtagg ctttccgtca ggtacatcac caccagtatc agatgatgga gcaagatttt
     9361 gagtagaagc ccaaagtctt gtgttaatga tgtagtcaga aacaacattt gttggtatat
     9421 ctccatcttt ttttgctgac tggatgccgt tgatataaac tcccaatagc gatcctgcca
     9481 ctggtaagaa tataaacaat acaaaaatac gaacaatcca tttttcaagt actggtgata
     9541 atcccttcga gttaacacca tctttcgaca ataatttcat tccttgataa cctagtattg
     9601 ctgtgaaaaa gagcatagat aagcttgcta tcgctttaaa taattcatta tttaatccca
     9661 aattgttaag caagctagtt aatgctttag ataccggatt agatacatcc gatccacctt
     9721 ctccccaccc cataagagaa aatatattca tactcatgaa aaattttcca aggagttcat
     9781 ttatggattc agcaatatta gaaaggatta aactaattga tccgataaaa ctaccaatcg
     9841 tcctaccaat acttcctaga atggatgatg cttgacttgc aatagcattt cctgagactg
     9901 tttcaatata tccgtagtaa ctataagttg ctaaagtaga tgctagttgc gtacctgcat
     9961 taccccctgc aatcgaatta ccttgtttag aaatgtcaga ataagggaaa tcggcactga
    10021 taccaccttg tcctaacaaa ttcatttgtc cagttttagc ggcactatca ttgacttctt
    10081 tatctcccat taggatacga gcatatagtg tccacattcc ttgttctgcc ggtttacttt
    10141 ccgcataagc aacgttctta tttataactg tttcttgttt gctatcttga ttgtcaggag
    10201 ttggatcatt cattccaaaa ggagcgccta aagtaactgc taatactcct ccaataacta
    10261 gacctcttac gacccatcgt tttattctaa ggttttgtag taaatatttc ttgaatttca
    10321 tagctacgcc cctccaatcg aaaatacaat cttgttttct ttactttcag caacggaagg
    10381 ctttgcaata atttcagcat tagaatcacc ttttccttca aacgctccgg cttcactcaa
    10441 cttaacatcg aatatttttg cgtttggata agtaattatt gcttcagtaa tcgcttcttc
    10501 aaactcagat tcaactaaat gcaagatatt ccttgcaccc cctgatttag aatcctcttg
    10561 tgaagccatg tcaaaaacta agtgcatgga gagatcgtct gcataaaaat tttgaccata
    10621 tactctttct ttcttaggtg gaagacgtaa atctatattt aaatgttttc gtactaattc
    10681 agcactcttc aacatttcat tataagcaat ttccagaaga gtttgttcgg ataaagccca
    10741 aaatggaact attcgtccaa atcggttaat aacttcaggc tttagacctt caccaatcaa
    10801 ggcttgtttg atccctgatg cgacttttcg gtattctctt tttagttcag tgctgtattc
    10861 attagaattt tccttgtttg taacacgaga tagtgagcta tatcggttta acgaatcgaa
    10921 catctccgca cctgcatttg ttgtcgcaaa taaaattgta tttgacaatg aaacggtgtc
    10981 gtgaacttct cgatcatccc atcctctttc agtaaaactt atcctacctt catctaaaat
    11041 tgataaaaag gcatcgagtg tttctacacc agctttctca tattcatcac acacaataat
    11101 cgcagaagga tcatgcctta catgagtacc tataagtcgt ctaaaacgca ttgcatcatc
    11161 tttggttttg tagtccggca tattaactaa gagaacttta ttttcatcgc cataaagtcc
    11221 tcttgccacg gctttagcca ttgcagtttt accgacccct gttgatcctg taaacagagc
    11281 agttgctttt ggttgctttc gacctttaaa acgatcaaat ccaagcttca tacgtttaaa
    11341 caacattgtt atagtataaa ctgctaacgg ttgtcctttt atggacttta attcctcttg
    11401 aagtttttcc atatcaaaat cagaatctag ctgaatatta tacttaccaa atatttgcaa
    11461 tagactttct cgattataag catttccgtc tactcgatct tttgcaatca aatcctccat
    11521 tacagcaatt gatttagccg gttcggacaa atcctcacga taaagtttgt ttgcttgtac
    11581 gatttcttga agtaattcat caggaatcct ttgcgataat ctaaaagaag cctgaggatc
    11641 atctttaaca gaggatgtat ttagccattg tctcaaaata tcgacgacaa catcgctttt
    11701 tagttcattc aattctaacg gttgtagccg tctccctaag gcatcatctc ttttgatata
    11761 gttttcatat tcttttcttg tagtagcggt aatcatttga agtgattcat ttgctaacgg
    11821 ttcttttagc gaatcacccc caattttatt gccactccca aaagagctaa caactttatg
    11881 aaactcgtca atgaagagga caaattcatt atctttgtcc tcagctttta aaattcgctc
    11941 atattctttc aatcttggaa ttaatgtttc taaacgtgtt tggaggacat catctccccc
    12001 aacacgcaat tgtccgattg ataatttata tacttgtact ttctttccat cttgtcgctg
    12061 tctttcagcc cattcacttg caagtgctgt tttacctgtt ccggcttcac ctaacaagat
    12121 agcttgcggt gtttccggtc tattcaagat cagtgacaac tcatggagtt cgtcatcacg
    12181 tcccactaac ttatgttttg gtggtttcat tggtgtgaga gcatgattaa attcggtttg
    12241 aatattctta aaaaactcgg tactattttc catctgtttg tgttcacttc ctctaaaata
    12301 agaataattt acttctagtc agtcaaagtt aggtacttaa atgtcgtctt catgtctcca
    12361 aaagaatctt tgttaaagtc agcatttttg tattgatcaa tcaatttttg tgtatcattg
    12421 attgctttaa tttcggtctc cattcgactg tctagttgac gaatactttc ttgcgaatct
    12481 ttatcgtcag gattttgttg taaacgttcc agatactcag cttttgtggc ttcaattttc
    12541 ttgatgttag tatttgaagc atttaactga tcttctagct tatttacaac attattctta
    12601 cttgtaactg ctacaacttt tgaataatca atatcgccat ctttggtaag aaagcttcct
    12661 tgatagacat tagttgaatc tgaatatgga tttattctga aattgatatt atcaggagta
    12721 ttaacaggtt ttgctttttt cccaaaagaa attactcctt cattattaac atcattcata
    12781 gaatattgag aaagtgcttt tgtaactgaa tctgcttcat tcacattgac tttggtatca
    12841 tcgtcagctg tatcatcacc agaaattagt gatacttggt ttgcaataaa aacttgataa
    12901 gctctttcct ctaatttacc ttttaggaat aagaaagcat ccccatcagt acttaacatc
    12961 ccatagctca tttcaagctt cttaggacga tctttttctt ttgttgccat atataagtta
    13021 tagttttttc cttgcgtaga taacaacttt ctagcgtttt gggagtaacc aagttttact
    13081 actgttacat ctctattttg atctgtccac acatctgaaa tagtgatttc tgctcctgat
    13141 cgagcaaact ccaatgaaga ccctataggt gttgtattgt tcacgagata ataattatag
    13201 tttcctaatt gataaatgta gctacccaag cctgttaata aaaaaagcac tcctagaaaa
    13261 gttgcaagca taatgcgtaa tccgtgacgt gttctcttat ccttatcacc aagcaaccct
    13321 ccaataatac tgtattgatc tttggtagat gttgaattga cgtttttttc catcagtttg
    13381 tctgcccctt tcataaaaga gcaaacaatc agacgttttt tcggtaattc taggttcggg
    13441 attttgaatc atttcggtat attcttcccc attaatattt aacacaaaaa ttatcttcct
    13501 ttcttcgttc ctttcttttg ctctttattt tccaaataat caatgatttt tgctattgta
    13561 ccaagatagt aattcccctc agctttgttt tttcggattt tgctaaccat tggagtaggt
    13621 acaatctctt catctctcaa ttcactgaaa gattttttac ctagatattt tccaataaca
    13681 gattttaaaa aacgttcaaa atctttctcg taagttgttt tcttgccttt tagttcatgg
    13741 ttcatattgt caacgacttt tgcggtttca ataattgttt tagttctcag cttaataatt
    13801 tcatctggaa ttttcaatcc tcgtaatttc atcgttgtac taactggtaa cccatgcttt
    13861 actgcatcag caatactaaa actttttaga tcatctagta agctctccat atagttaaca
    13921 aattcatgcc aattaatagc attcattgtc tcaccccttc atttttttaa aatgaggttc
    13981 gggcgtaaca catttatgtt attataatat cataataaca taaataaatc aatcagcaaa
    14041 tttagatatc ccttaaagta tcagcaatta ttcaacaaga tatttatttt agctatttca
    14101 gtcatcataa aagactaatt agcaataaaa taactaatat tatccattta tcagacgaaa
    14161 agaaaaaact tatctaatta ctctatatta acttttaaca aatagttgac ttgtccaaaa
    14221 atgttacctt caatctcaca aagatattaa gatgtttcct accaaaactg atatcaccgg
    14281 actttttatt ctgtgttgtc caaaagtgtt acctttagtc gatcaacaaa ttaaaaaaaa
    14341 ttgttttttt cttgacttgt ccaaaagtgt tacccatagt tgttaaaatt tgtatagatt
    14401 agccattctt tcgaatatta tttagactga aacttgctta caaaaaaact tcttgcattt
    14461 attgtccaaa agtgttaccc atactttttt aaagaagcag gttgtattaa aattacaacc
    14521 tgcttcttct caatcttctt ctaaccaatt atgcattgaa atggttggca agtttgattc
    14581 tggctcacta aaagtgaatc tgagccgatc aactcttctt cctttctttg catagatttt
    14641 ttcataatca aaagtttcaa atacctgtat tccgttttca tcaggagcta aaaattcttc
    14701 tttcgcctgc tctagtattc ttttgtcaat atttgtcatt ctataacttg aaggtatact
    14761 taatgctctt ctaaaatctt caactttgac tacccaataa ccatttcgcc actctttatt
    14821 tctgtattgc atgagatgac gatacaattc ttttgtgtag ctacttctta gttttgtaaa
    14881 attatcaagt tcaaaacgag taaagttttt gccaattgag tttaagataa attcaaattc
    14941 ctcatttgcc ttaattgtaa ctgtttcctt ctgtttatct atccggaatt tttgaaaaag
    15001 ccacagctgt tcatagacgt ctgaatcttc aaaacggtag gttaaagtac ctagtttgtc
    15061 actcaaagct tttaacacag aataaaaact gtccttttct cttctgtcgt atttgaccaa
    15121 ataacgaaag aggttgaaat caaaagttac ttctgctgtt ccttgacgtt tcatttttga
    15181 taaaatagcc caaaacacat ccatttcaac aggcttaaat cctcgcaaag ctgttgtatt
    15241 cagaccattg ttataacgca caattgcatt tgtttgttct gatactaaat ctacatcact
    15301 atcaataatc ttttcggtaa cttcttgaga cattgattac tctccaatct tctttttgcg
    15361 ctcctttaat catgttaatc tggtactaat taaaggaaac aattttttct gcttgttacc
    15421 taaattaaat cacaactaaa ggtaacagtc aacaaagatt tgttactaat ctaattttct
    15481 attttttcgc cttccaaatc aagaaaaccg aaggtaacgt cttatcctag tgtgatacct
    15541 caaatgtcca cttttgttac ctttgctgtc caaaagtgtt acccttactg tccacttttg
    15601 ttacctttac tgtccaaaag tgttaccttt ataccccttt aatacttact ctcccaagag
    15661 attaagcctc ccctaacaga tatattaaca gatatttaac agatatatta acagatattt
    15721 aataaaggag gattactcct ctcttatttc aaaatcttaa aaataaaaaa tcttaaaaaa
    15781 aactaacact atctaggagt ttattttgct tgtgtaactt tgaataattg aaaaaaagga
    15841 aaaggaggaa gcttcagctt ccccttttat ttatatttat aatatatatt ttaatcttta
    15901 aaactttagc aaccttcaaa aaggctttat atcaatctta aatagatttt agggtggaca
    15961 taaagcgatg cgaacatgga caaaaagcga tgtgaatgtg gacaaaaagc gatgcaaacg
    16021 tggacaaaaa gcgatgtggt attccgaata tatccaaaaa aagaaaaagt atgtgaattt
    16081 atttctaaaa actagaaaaa tatttgtttt ttaattttgg taatttttat aatttcgtat
    16141 ttttttgaaa aggattttta tattgaaaat gttctaaaat agcgatttct gctgtcttat
    16201 caatgaaaat tgattaaaaa aataaaatgt gttttacaga gattgagtta tgttataaat
    16261 ttacgataca tttcttattg tatcgtatcg aaaacaggtc tatacttatt caatggaatc
    16321 gtaccagttc caaattttta agctcgtacc aagcttagaa agaagaggca atcgtatgaa
    16381 aataacagaa aagaatgtaa acccgaaatt tgaacctacc gaaagcaatc taaaaaagtt
    16441 tgatttaact gttactttat cgaatgaact tgtagacagc attgttgaaa tggatgctat
    16501 gccacaaaaa atttatcttt atgctatagg acatcttgac cctaaaaatc cgccttttaa
    16561 taatactgtt aaagtatcta aaaaggcttt atttgcgttg atgtcttcta gttcatcttc
    16621 ttcaaaacat tcaagattaa aacaagttat tgaaaaattg catcagcaat ctgtcattaa
    16681 aattcaaaga actaaaccta acggtaagac tgaatacaaa gtcatctcac cgctagaaat
    16741 tactgaattc aatgattttt ctgatgcagt atctattaaa tttagtagtt caattatgcc
    16801 tttattaacg aacttagaag atcattttac gcaatatgca tttgatcaag tagttaactt
    16861 gacaagcaag tatgcgatca gtttttttca attattcact aaagatttta atctgtattt
    16921 agcaaataga gataacttaa catggagtac aaaatcactt gatagattaa aaaatcctgt
    16981 tttctccatt gcagatttac gaaagaaatt tagtattgag aaaaaatata aagcttttcg
    17041 agactttgaa agacgtgtaa ttaaagaacc gattgcccaa ctgaataaat acactgattt
    17101 taaaattgac tatgagctta tcaagaaggg gcatacttat acaaatataa agttcttgct
    17161 tacacgtacc atgtcagttc cggtacctta taagcaagaa caaagagacc ctgcttattt
    17221 aaaaggcgca gaagataaaa cagagaaaat gaatcaatcg tacttgaaag ctatgaatag
    17281 caaatacact aaattactaa tcaaaaactt tttgatcagt tctgccgact tatgcgatct
    17341 taaacttatg agccgacttc agaataaagt ttatccgctt tatgatcgtt tatccaaaga
    17401 tagaggattt gaatcagttg tcaatcacct atcttacgtt gctactcata aggaggatta
    17461 cacaataaaa aatactgtta aatatctcga aaaatcaatt acgagttatt tgccttatgt
    17521 gaacctttat gattaacaac tgaaaaaatg cgtgaaggaa ggaaaaactt ttgaaaaaag
    17581 atgaactgac aaagtacaat gaggagttct tagcaacaat tgacatgaaa atggatttaa
    17641 agtcgtatga actttatcaa ttgctgttca gttatatctc acccacaaag ctaaagaaaa
    17701 caggcgtagt agatttacct gttaaagcga ttattaatta catggatgtt gatcaaaatc
    17761 ttgaaacgga actaaaaacc atagttaaca ctttgcaaag acaagcagtt tatgaaattt
    17821 cgaatctaga caaaaaatat aagacgtata ctactgtatc tgctattgat cggattcatt
    17881 gggatttaga agagcatagt gtatctttca gtttttcaga agatgtaatt cccttaattg
    17941 tctcaatcaa aaagaagtat ccgttctttg tttttgaaga cttagcatct tttcaaaaaa
    18001 aatatagcat cgtgttatac aaatatttgg cgatgtatta taaaaaatat cttatcgcca
    18061 aaaataaagg agattttgag aaagctgaaa tatataagaa tcccctgatt gaaatagtta
    18121 aaattcgtga gattacgaaa acagaaaatg agtataaaac aatatcgaat tttgatagac
    18181 gtgttttaag ggaatcagtt gaggaaatta atgaaaaatc aatgctgaat attgattttg
    18241 ctaaagttag aaaaggcaga aattacaatt ttgctgtcca gtttaatatt tctagtgagt
    18301 ttgatgaaaa aacttataga gaaaaaaaat taggttaatg caaaatatat cttactcgtt
    18361 tgaagatgct tcagacgtat gctaagatat atagtgcctt gggagcaagg tattaatctc
    18421 ctttagaggt taattagctt gtgatcgcct atcaattttt ttggtaggcg attctttttt
    18481 ttgaaacaaa aaagcaaaaa ttatttttta attagagagg tgcaatgcga tgaaatactt
    18541 tttttgtgca gtattcgaat ggaaaggaaa tgaatatgca gttaaattcc cagattttcc
    18601 agacttatat acacatggtg aaactttaga agatgctttt gagatggcgc aagaagtatt
    18661 ggaaggatac ttggtgcttt tagagttgca agaaaaagaa attccatcgc ctacgcctgt
    18721 tcaagagtta aatgcaagaa tcaagcgatc tgagaatgtt aatttatttg tcgtaaaagc
    18781 taatacgaaa gttgctaaag ctcgaaacaa gcaaaattat gatcgaaaat cagtgactgt
    18841 ggaacactat ttaaatgttt tagcggctga agagaatatt aatctgtcga aagctttgaa
    18901 tgatttgttg agagaaaagt tgatttgatg tctctcagat gatcatatta agcaaaaaca
    18961 gcttgtttta ggacgtatgg atttaagaaa gacaaattat caaagaatat attaaaagct
    19021 ctcagaagcc ttctgagagc ttttaaattg ctatgtattg tactgcatct gctcaaattg
    19081 attttctttt catgcttacc atgtatctaa ttttccatca agtaattttt agatatgtat
    19141 tgagtaataa atagcaaatt tgcttgatat aagctcgaat taggtgcttt gtaatgtgtt
    19201 aggataaaat tatacaagaa aatgtcaaaa gctctcagaa cgcttctgag agctttttat
    19261 cggtaggctt gtttaacgtg atcttgaagg ataccctttt gatgtttctc tcgatccctg
    19321 catcgctaat tactaagtgt tcttcaagtg tgatgtaggt atataaatta agcatcaaaa
    19381 tggtgtagat aagcaaaaaa ctccctaaaa ctaagtgttg attataaaaa tctgacttat
    19441 aaaaaagaac tgagaatgtt agtgttgatt cccaaaaaag aaacaaaatt ttgtatttcc
    19501 aaagatagtg gatcaagcgc tgtgctttac ccatctcaaa taatttataa taacctgcta
    19561 attgatcagc aagcgtatcg ttaacggttt ctgtttgtgt ttgtttcatc tttctcttct
    19621 cctgtttcaa ttaatctaaa atttcagatt gagcaagcaa ctcattgtgg tagtcggttt
    19681 gaaattcaaa taacaatttt gccttcttaa cgaggtttaa agcgttcgtt agtgattcac
    19741 ttaatgcttc aacatcttta actgattttg catgtttcat tttttcagtg tgcgtatagc
    19801 agaattcagg tattgagtta ggggttgcct gttcaataaa catctcaatt cgcaagttat
    19861 tatcctcaaa aataattaga tcattggcaa agtgtttggt actaacgcta atgccagttg
    19921 tatcttttaa tagattattg attaacgttc gagagaaata gtttaagtgt gtagctttca
    19981 taggttcggt ctccttttta cttttcaagc aactcttctt ccagtgcttt ttgaagtagt
    20041 tgagagaagt ttatgttttt ctccttccct aaaagaacta accattccgg aacactaaca
    20101 ttttttctaa ttgtttttgt atttaagctt cttcggaaaa gtttaatgtt tagttggatg
    20161 attactacca cttggttggc tttcaaagtt aattcttcca ctgctgatgg tttaggaaat
    20221 tctgcatctg gtacactata tagcgctaat cctaaagcat ccttagcgtt taaatatgct
    20281 tcttcaagac tatttccaaa ggtagatatt tccggtaagt cagggaaaac gatgttataa
    20341 gcttctcctt ctttctcgaa gattgccgga taaaaaatat tttttgtctt catttcctcg
    20401 ctccttttct agtgtaagag aggatagtat gcctaatacc aaataggaag gcaaggctgt
    20461 taaagccctg cttgcttcca gatattagct tctgttccta gtggtacatc accattgtgg
    20521 atcggaacaa cgaccgttct tttagtcttg gaattataaa attttgcatg actgccagtt
    20581 tgtccagtct ttttgaagcc gttagatttg agaattttta caatttctct tgctgtctta
    20641 ggcatagcta ccctcccttt acaaaatcta ttatacacat tgttgtgtat ggaatcaata
    20701 gaaaaagagg atgttttatt gcaaaactaa taaaatgatt tattggtttt ttcagcaaat
    20761 tgaatgttat tagcgttgca aatattcatg atttcccaag tatcatcaga agtataggta
    20821 tctaagaatt cattgacagt tacggttgat tcgtatggtt cataagtcaa agcgttctcc
    20881 aagtcttttg atgaaataat caagactttt tcaatttcct ccccttcttc atctatgaaa
    20941 acatattcta aagtgatttg ttcttcatcg gtataattca tattgtgttc tcctttcttg
    21001 tactaagaaa aatggatatt tccaattgca tcccactcgg caccattgtg gtataggacg
    21061 tgaccgagcg ttacgccttt gaaatgttct tctaaataca tccaaacgca ttcaaggcta
    21121 gtacctgctt tgagattgta gaagtctgca tccaatacct tttcagaagt tatcggatca
    21181 atgcgagttg gtacttcaat aaattcagtc caaatttctg caaaagtctt accttccaaa
    21241 gtccacactc cctatcaatt aattccaaaa gcaaatagag aaatcaagcg accgtcaata
    21301 gtcacttcaa caactgaaaa tgccgttgaa acagttttaa catctacact ttccaagttc
    21361 ccgatgaagg aatctttgtg ctttagaata gctttcttta gctgtctgtt atacacttgc
    21421 cgactgttaa actttttgaa ttctcgatcc ttgatcagct gtttaacgat ccctgcatta
    21481 attgtataac tttctgcaat agcaacgtga gtaggttgct gtaaagtagc tgttagcatc
    21541 ttgtcactcc ttcctaaaag ttaattagct tgtttacaaa tacattatac acatcggtgt
    21601 gtataatgta aagagaaaaa ggtgctaatg gatcagctgt tctaaacaaa agaaaacgat
    21661 aaagtaacaa ataaagtcag caaagttaaa aaggatgaaa cggctagtcc ggttgctttg
    21721 cttgtgtgat tttcggcttt cttatagatc aaataggaaa ttatcagtga tattccagta
    21781 aagaataatg tactagctgt cactaaaaga aataggttaa tcatacgata cactccttct
    21841 gtaatattgg tatcagatac gtttaaatgc gtttctgagc tgttttggat cagatggtga
    21901 tgtttttagc cctaccctaa aaacaaagcc cagaaaagaa tttaaaagcg ttcgtaccta
    21961 atacgtttat attcatatac atatacataa acataaacgt gtatacgttt atgtttatgt
    22021 atttaagttt taggctactt ccttaacatc tcctgctgat agtcgagtga accgagtgag
    22081 tgatccatct tgtagtcgaa aaataaagct acgtttgagt ttatactgat agacagcgac
    22141 atacgatcca tcccagattg agtaagtttt acctgcaact aataagtcat caagttttgg
    22201 tttattgctt tcttctttaa ttctatctag ttgtcgctta accatttttt cttgatcacc
    22261 gacaaagaat ttcaaccatt ttttcggaat tttcttaaag taagcaggac tgtcatttaa
    22321 gaagtagatt ggtttgtaca tttcatctcg aaagatgaag ctgtcaatat cgtaggttcc
    22381 ttctgcatct ttgaaaagga taattccata gatcttcgtt actttggtat ctacgatttc
    22441 caaaccattt ttggcgtacc ctttcttttc ttcgatcact tcatttgctg atgaataatc
    22501 accataccat cccataaaaa atcgctcctt ttgaaagtta attagcttgt ttacacttat
    22561 attatacaca ccggtgtgta taatatcaag aggatattgt tcttttttag gtaaagtggg
    22621 atcgtaaaca gtgattttgt tgggttaaca aaaaaacaga caagccttat cagcttgtct
    22681 gttacttata aacttcactt ctgtgaccaa tagacaatat aagaattgtc acttcatgct
    22741 cgctaatatc agctattata cgatatgcac ctaccctata tcgccagtag cctgatttat
    22801 tagctgttag acctttacca tgctttcttg gatcatcagt gcctacaaga tttttctcga
    22861 tccagtttag gataaccttt gcctgaaact tatccatttt ttttagcgct ttttgagctt
    22921 cacgttcata tcttacttgg taagtcatct tataagccta actcttttag catatcttcg
    22981 tgggaaatac tttgatcgtt ttcctcatgc tctttcatta gttgcttgta ggtggcaaag
    23041 tctactaacg tttctgctgt ttgcagggaa ttactacgca taaattcaga aatgttatct
    23101 ccgttgaatt cagcaacttt ttcaagaaaa tctttttctt ctttagatac acgaatactt
    23161 attactggca tagtttatca actccttttc aattacattg tactacgatt gtatgacaaa
    23221 tgcaatagtt atatatttga atatatacat aaacataaac atatacatat atatgtttat
    23281 gttgtagaat ataaaagcaa atataaatat aaacacgttt atgtatataa acatatacat
    23341 aaacgtgttt atagtgtata atggagttac aaaaggttaa taagggaggt ttaatcatgg
    23401 aaaagaagtt gtcaatcatt actggaaaca ttgaaaaagg tggaacaggt aaaacaacaa
    23461 caatctacaa tctaggtgga tatgctgtcg aaaatttagg tatgaaggtg ctgtatattg
    23521 atgaagataa gtcgcaaaac ctatcaaaac gatttcctga tgctttcagt aaagcgaaaa
    23581 gagagaatac aatcaatcat ttatatcttc atggatcagc tgaaccttta gctataaatg
    23641 agaacatgga tattttagta gcaggtgaag atttaaaaca agttgagatg caaatgcgtg
    23701 atatgcctaa caacagaacc ctactgttta gatggatcgt tgttaactat gaacagctta
    23761 aagagaagta tgatctaatt ctgattgata ctcataatga tgcaggtcta ctagctcaaa
    23821 atgcttgggc tgtatctgat cttgtcgtag gcatttctga tccatctaaa gatggttttg
    23881 aagctttgct gaagcttggt aaagatattg atgcactagc aaaacagttg attgatatta
    23941 agactggtga aacactgatg gaaactaaat acgctacgat cggtagcagg atcaaacata
    24001 atactaattc aagtcgtgag ttcctagaat tggtaccaac gttatctaat tatcttggat
    24061 atgtacaaga gaaggaattg cttaatgcaa ctagcttaga aggtaagaat attgctgagt
    24121 tcgctaagga taagaatatc tatcgtaaga ataaggattt ctttgaaagc acgtttacgc
    24181 tatacaacaa aataattgat acggcacaag aataaggagt gattgaagtg aaagaaaata
    24241 gatttaaaaa attcgctgaa gctgaagtag aagaagttcc tgaagtggtt gaagcagttg
    24301 aagaacctaa acaaacacct aaagaaacaa caagttcttt ggtagctaaa ctaaaaagtg
    24361 atagttctga aaagaagaaa aattatcaat tcacgcttca accatcacaa agaaagaaat
    24421 tatctaaaat cagcgaaaag ttaggaattc gatcagattc agctttactt ggtgaaatga
    24481 tagataactt gtatgatgaa gtttttggtg agtgatcagt ttaaagctga tcactttttt
    24541 tattggaata agcggttagg tatagcttaa ctaaatttcg tatacgtgtt tatggatata
    24601 tacgtataca tgtttatata catgtatacg tatatgttta tgtttgtatt tgtacataat
    24661 aaaaaggcta ggtattgtaa cctcgccttt ttatttttaa agtaagtctt tgttacttgg
    24721 tgcattgaac ccttttagca ttggcttttc tttctttgct gaatgatcgg atgtaaccgt
    24781 tgaaggatgc tcttgttgaa tagggttatg atcagttggt ttcttcttta cttctgctac
    24841 tttgctatcg tttctatcgt tgcctgcttc aataattgta acttcattgt tctttacacg
    24901 ccgatatagg ttcaaagctt ttttgatcgt ctgagagtat ttaacgccta gtgtttcata
    24961 ttcggattca agaaactctg ctaaaggtaa ctcgctaacc ttttctctat tgattataac
    25021 tacataacgc tctgattttc ccttattcat gttgatctcc ttcgctgttt tattgagtta
    25081 aaccaaactt gtaaaagcct tttacattag aaaattcact gtcttcaaca aacaaggtat
    25141 gcggaatttt atcttttaca agttgtttgt cgataataga agctccacca ccagtaaaga
    25201 caactttatc taaggttgtg aagtttttga atgtagctaa aacttctgca acaaccatat
    25261 tggtgtatgt ttttatttct ctttcaacta cttctgaaat atcaaaactt tcatttccgc
    25321 ttggcttaaa tagatatacg cctttttctt tgccttctcg gataatcttt tcaagttgga
    25381 aagcattagg actgatcgga aggtcaagca tatttacgat acgattatat aaagtaaaaa
    25441 tgccggtatc cttttgttca cgattgtttt cgtcaatttc aaaattttgg acaacatcaa
    25501 aaagtttcgt gccaccacca atatcaacaa aaccgatctt ctgactgatc aatgtttcat
    25561 cttgtacact accatcatca gcaagtagga ggttatatag tgttccaatc ggctgtggca
    25621 gtacccaaac ggtatctacg tttatattat aagccttacc gtcaacttca actgaatgtt
    25681 gtcgtgtggc ttgttgcatc acgtatttga cgattgtttc ggtatagtcg gatgaaggca
    25741 gacctaaaac tagattaacg gttaaaacgt catcagattg atcttctaaa cgtgctaggt
    25801 tagctaaaga gaaagatagg atatttttgt aggtttcctg cttgtatctg ctgatcccaa
    25861 aacctagtga ttctatcacg tagtcatctt ttcctagctc gtgtatatcc ttcccaaaat
    25921 aatagctttc agtagtgttt actaggctat attcagaaac gtttagtgat cgttttaatg
    25981 aggaacctat attagaaaaa cgtcctgaat taatgatatt tttgttcaaa atacgagagg
    26041 gaagtgagag tggagaaacg tgtgtactca tttcttttac tgatttattc cctaagtcaa
    26101 cggaaaacaa taatggttct ttcatggtat gacctctttc tgtttgtgtt tatggtattt
    26161 cggtacgaaa atagtttaca cctatttact attagttgca actgtttata agaaaaaaat
    26221 gcaatcataa aagtctaatt aattataata aagtgtaaat aaaaaggtgt aaataaatgc
    26281 ttgcaaattt atcttattat gatattataa aatcataaat tatattaagg agtgatcctg
    26341 atgcgattga gaagaaataa gaattacact accattattt tagaagattt tactgatcaa
    26401 gaattactta ttgtcggtaa aacaaaagca gattttatcg aaaagggaaa tgcttcaata
    26461 gtaaaagctt caaaggttgc tgtcgaaaaa tattttgatt ctttagaaga aagtgctaag
    26521 gaaattttta atggagagaa agctggtagc tatgagttag acggtattag atttagcttg
    26581 atcccaacaa ctgaaaatat tattccgaag aaattatatt atatcttttc atctgaaaaa
    26641 catacttcaa tgaagccttg tatttttgat tggcaatggt tgattgatgc tgtattggat
    26701 gtaaaatgtt caaaatacaa tattactttg gggtgttaat tatgagtatg ctagttagaa
    26761 aattaccatt atctgtaaga gaatttctat tttacttggt ctgcttaatc gcatcagggt
    26821 ttaagctgat cgaacatatt tttatctttg cttatgtatt agcaatgatc gcatttttat
    26881 ctggcggttg gttaattatt tatttgttaa gctaagtttt agatcaaaaa taattagtaa
    26941 attaaacgat aaaataaccg ttaataaatg taatgaaagg acaacgccta acaatcagct
    27001 tgtaataaga ttataaaata acataatatc aaaaatagtg ctttttaaag gacaaattaa
    27061 gtgtatcaac ataaacgtgt atatgtatat gtttatgttg atactttttt tgtcttaatt
    27121 ttttattttt aaaattctat ttactaatgc tgtatagata gtgatcagaa aaaacaaaat
    27181 agcgagatta agctatttat tagttcatat attatattca gattaatatg atccagtatt
    27241 aatctgaagg caaaaccaat atatttctac ggactcttgt aaaactattt aaattttcct
    27301 gctaataaaa taacgaaaat agaatattta gcttttttat accattttac gataacatga
    27361 tttcatttgt aatattaaaa catttaaatt tttaattatt ctttcaaatt agatcaatta
    27421 atatccttat aaaagagcat aataaatggt ttttacatcg ttatttattg atattaatct
    27481 catccaaaaa aaatgaaaac gcatactttt atgggtgatt gaatgtgatt ttaatacata
    27541 taccaattaa aagaaaactt tttagatttt tacttacaaa tttataaaaa aacaagataa
    27601 ttgatacttt gattttgcga acattttatc ttgccgccta attcagcttt aatatcatga
    27661 ttatatcagt aacaaatcgc ttttttagct aatttaagca tcaaataatt attcttaatc
    27721 agggaaaaaa taactaataa atggattttg ggaataggta aaaacttgat cggtttctgg
    27781 ctaaaaataa cgtgaaaaag gaaatataaa ataacatgga gcgtgggagg aataaagaaa
    27841 ttttacacga aaggtgcgca gggatgtaaa gaaacttaac acgaaacaaa agt
//
LOCUS       DADGKS010000031        27092 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.031, whole genome shotgun sequence.
ACCESSION   DADGKS010000031 DADGKS010000000
VERSION     DADGKS010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27092
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.031"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(14..946)
                     /locus_tag="JXV47_001474"
     CDS             complement(14..946)
                     /locus_tag="JXV47_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HAX1487525.1"
                     /translation="MLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            complement(1385..1837)
                     /locus_tag="JXV47_001475"
     CDS             complement(1385..1837)
                     /locus_tag="JXV47_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAX1487526.1"
                     /translation="MHLNKYWILEEIEKLFVEFGSDAINPYKIIKYSDIDLIETDLGN
                     KTLGQTIHNKRCYVILINQNLSPSMKRFVLWHEIAHVRLHKGICTAAFRANNLSCMIY
                     GIEAEANMFAIEMLTRTIDEQDLSDMSQFQIIEYLGLPHNLEHLVLQH"
     gene            complement(1850..2260)
                     /locus_tag="JXV47_001476"
     CDS             complement(1850..2260)
                     /locus_tag="JXV47_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1487527.1"
                     /translation="MLLDRIKILLKERSMTLAELERKLNFGNGSMSRWNKSTPSGDKI
                     QKVADYFNVSTDYLLGRTDKRHYYDLTEKDKQDIALQAEKLLEGLNSDAETNYYGEPL
                     DDEDKEKLYDAIQLALALTKVKAKKKFTPKKYRQ"
     gene            2535..2747
                     /locus_tag="JXV47_001477"
     CDS             2535..2747
                     /locus_tag="JXV47_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1487528.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            2750..2962
                     /locus_tag="JXV47_001478"
     CDS             2750..2962
                     /locus_tag="JXV47_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487529.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            complement(3254..3478)
                     /locus_tag="JXV47_001479"
     CDS             complement(3254..3478)
                     /locus_tag="JXV47_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004401476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAX1487530.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            3556..3744
                     /locus_tag="JXV47_001480"
     CDS             3556..3744
                     /locus_tag="JXV47_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487531.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            4070..4405
                     /locus_tag="JXV47_001481"
     CDS             4070..4405
                     /locus_tag="JXV47_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487532.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            4638..5579
                     /locus_tag="JXV47_001482"
     CDS             4638..5579
                     /locus_tag="JXV47_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HAX1487533.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            5581..6471
                     /locus_tag="JXV47_001483"
     CDS             5581..6471
                     /locus_tag="JXV47_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HAX1487534.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            6514..7314
                     /locus_tag="JXV47_001484"
     CDS             6514..7314
                     /locus_tag="JXV47_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAX1487535.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADDIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            7329..8180
                     /locus_tag="JXV47_001485"
     CDS             7329..8180
                     /locus_tag="JXV47_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAX1487536.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            8177..8380
                     /locus_tag="JXV47_001486"
     CDS             8177..8380
                     /locus_tag="JXV47_001486"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487537.1"
                     /translation="MNLTKQEKRICRQIMLQIIGDRDMDELSQQESRMVRKISKLIIY
                     RDTERFLTVLGNVYENPELLEVE"
     gene            8381..8842
                     /locus_tag="JXV47_001487"
     CDS             8381..8842
                     /locus_tag="JXV47_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010781228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAX1487538.1"
                     /translation="MPKILDACCGSRLFWFDKNNSDVTFMDCRQQYEELSTGHVINVD
                     PDVVADFRDMPFEDDVFDMVVFDPPHLRHVGENSWLAKKYGKLDELWPEDIRQGFAEC
                     MRVLRPSGTLIFKWNEEQIPLSDVLEAIGEQPLFGNKRSKTHWLVFMKKFS"
     gene            8868..9320
                     /locus_tag="JXV47_001488"
     CDS             8868..9320
                     /locus_tag="JXV47_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487539.1"
                     /translation="MKIVLNKCFGGFGLSHEAKMEIFKRKNIEVFPYINNFSYDSDDE
                     YTRYTGQKLGSMDFIYYFKKDPKIDKVTGIYSEIDRLYGIADDSSFSSDSNRGDKDLV
                     AVVEKLGSEASGPYASLKVVDIPDGAEWEISDYDGVETAHYGFQTGSI"
     gene            9426..9620
                     /locus_tag="JXV47_001489"
     CDS             9426..9620
                     /locus_tag="JXV47_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487540.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVVINAQGYDNEFFKQITDISIQQ
                     GMEDEDGNFIDEVAILVTCE"
     gene            9651..9944
                     /locus_tag="JXV47_001490"
     CDS             9651..9944
                     /locus_tag="JXV47_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487541.1"
                     /translation="MKLKDGFYSSGHGIGGLMLDMPTKNPKTRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVVRLVDMEVIKS"
     gene            9974..10414
                     /locus_tag="JXV47_001491"
     CDS             9974..10414
                     /locus_tag="JXV47_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAX1487542.1"
                     /translation="MSVIPQLEGEEAIVNILENIDIKQTRKNARRLLKRYRNLERLVG
                     PVKIDFSVMTVTKNLKFTIDSQNEEIIEAISTRDSVIEALTRLSRIHFQVLYYSYCFP
                     NKMSMYQIGEKLGYSDRTIERMKAVALVEFAEAYKSGELISRTK"
     gene            10489..10956
                     /locus_tag="JXV47_001492"
     CDS             10489..10956
                     /locus_tag="JXV47_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HAX1487543.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQHR
                     EPKVTASYSLVPPSTADHIFEAERMLIDKEEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            11703..11933
                     /locus_tag="JXV47_001493"
     CDS             11703..11933
                     /locus_tag="JXV47_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487544.1"
                     /translation="MRNYWYVSLTNEYPRTIDDCSVRVVRSVQIKGKYSIVEMGREAE
                     PCEIDACKLVYCGHGFYDEPNIQNNINKNLRD"
     gene            12092..12925
                     /locus_tag="JXV47_001494"
     CDS             12092..12925
                     /locus_tag="JXV47_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small subunit of terminase"
                     /protein_id="HAX1487545.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELISNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPVGNKNALKTGEYET
                     IFFDTLTDNEKDIYSSLNDDPSFALSEEIRLLKIRQLRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKTPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            12918..14333
                     /locus_tag="JXV47_001495"
     CDS             12918..14333
                     /locus_tag="JXV47_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAX1487546.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPESMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTKVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            14345..15874
                     /locus_tag="JXV47_001496"
     CDS             14345..15874
                     /locus_tag="JXV47_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAX1487547.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEDMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKAPTAKAEYVTKNLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            15966..16844
                     /locus_tag="JXV47_001497"
     CDS             15966..16844
                     /locus_tag="JXV47_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HAX1487548.1"
                     /translation="MMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            16846..17163
                     /locus_tag="JXV47_001498"
     CDS             16846..17163
                     /locus_tag="JXV47_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487549.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            17212..17913
                     /locus_tag="JXV47_001499"
     CDS             17212..17913
                     /locus_tag="JXV47_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HAX1487550.1"
                     /translation="MVEWWGATIKTQSNAGRENESWGERRMSMKHKSLMPMNLQYFAE
                     GDDQKFSFDDFKSFVESNEEAQKFIQSQSQSVADKQLEAWKQNNLDKIKQDTIKEYEE
                     SKKNKSPEQIQLEKLQAEFEAEKALRVTSDNKAFVAEQIAGLELDGELKESISQFMLN
                     NLVSSDTDFTKNAVEGFTSVLNAINEKHADALKELQMKSAFGGTQQSNNQVQQNNETL
                     TNPEEQLGQILQQFN"
     gene            17928..18818
                     /locus_tag="JXV47_001500"
     CDS             17928..18818
                     /locus_tag="JXV47_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HAX1487551.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            18841..19056
                     /locus_tag="JXV47_001501"
     CDS             18841..19056
                     /locus_tag="JXV47_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487552.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            19068..19409
                     /locus_tag="JXV47_001502"
     CDS             19068..19409
                     /locus_tag="JXV47_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487553.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            19409..19780
                     /locus_tag="JXV47_001503"
     CDS             19409..19780
                     /locus_tag="JXV47_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487554.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            19773..20168
                     /locus_tag="JXV47_001504"
     CDS             19773..20168
                     /locus_tag="JXV47_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HAX1487555.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGEVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            20170..20547
                     /locus_tag="JXV47_001505"
     CDS             20170..20547
                     /locus_tag="JXV47_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487556.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNNPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            20548..21156
                     /locus_tag="JXV47_001506"
     CDS             20548..21156
                     /locus_tag="JXV47_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAX1487557.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            21156..21497
                     /locus_tag="JXV47_001507"
     CDS             21156..21497
                     /locus_tag="JXV47_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487558.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            21739..24528
                     /locus_tag="JXV47_001508"
     CDS             21739..24528
                     /locus_tag="JXV47_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HAX1487559.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANPFVLIIGAVVGAI
                     AVFGYFMATNEELRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNGIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTGFKLTLINIWNEVVNQAKSIWLNIKYFFINLWIDIKYFAIQKWIELKFSIIQTWID
                     LKYNAITTWNNIKQFFKDTWKNIKDTAYNTWISIKNTMINTWNNIKDSFWNIVTGIVN
                     SAENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLINGVKEKWNALKDTI
                     KGIAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTP
                     SVQPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQ
                     MKRDAGAVGGTLYAT"
     gene            24518..25258
                     /locus_tag="JXV47_001509"
     CDS             24518..25258
                     /locus_tag="JXV47_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAX1487560.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            25255..>27092
                     /locus_tag="JXV47_001510"
     CDS             25255..>27092
                     /locus_tag="JXV47_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487561.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCGIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     VLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWR"
BASE COUNT         9701 a         3897 c         5389 g         8105 t
ORIGIN      
        1 gctttttata tatttaatct tttgacaatt ctaaagatcg tctatattgt tcagctttag
       61 ctaattttgt aaatgttact gttccattat aattttctaa aacaactttc tctatttcgt
      121 ctagtgaaac tttgaaaaat tcttttcttt gattaatttt attaacttct tgttttctaa
      181 aatgattatg caatttagtt tccaaagacg gagcgtcctc tgaaaaaatc atcgcatgaa
      241 cgtcaaattc aaatggaacc gatgcactac tcaattcttt tattctatcc ataggttcta
      301 atcttctagt cataccaatt ttatatatgt cttcaccaaa agacccaata ttactaatta
      361 catacacata accggctcta gtatttaatt ctctttgtaa tacattttca cgtataactt
      421 ctaattcttt taatttttct tccagttctt gaattttatt tgcatataat tctttttcca
      481 catctgcatt agctttttgc atatatgcga ttaatttgga aatttcagaa ttgaattgac
      541 gttgttcttt atcaatacgt ttcttttcac gatcaatttc tctacgaact ttttcctctt
      601 ctatcatctg ttcttttatt gctttttgtt gttctttttc ttcggtaatt ttcactaaat
      661 aagagtaatg aagttctagt tcttgaagtt taaactctaa aagacccttc cttaattcag
      721 cattgtcatt cttgaataaa ttattaattt tatcaaatat ttttatgatt ttttccctag
      781 tcgagtctat attagaaata gttagtttat tgagtaatcc tttcacttct gaatcaaatg
      841 gaatgagcat ttttttcttt aaattatttt tctctcgttt atttaaaata agagggacag
      901 aaacagcatc gtcaataata tattcctttt cttttaattt taacaaagaa agcttatttt
      961 ttatttcaga agatgaagtt tcttctatat ttgaaacgat aagtgaagaa tagacatttt
     1021 ttaatgtttc atcatacttt tgatttattt catcatttaa atcttctttc tcttttttta
     1081 ataaaataat atcatttttt aacatagtaa tttgtttatt taaatctgat agtgtttctt
     1141 ccttacttaa tataaatctt tctctatcat gtaatttatt tagtttttca tcattttttt
     1201 gttctaattc ataagcttct ttttttattg tgttagcttt cgacagttta gtgattccta
     1261 taattaataa aataagtcca atcaataata acattcaaaa ctcctcattt ctttgatata
     1321 attattgtag agtttactca gaaatgagga aagagtccat gtgaaagcat gggctttttt
     1381 atttttaatg ttgtaatact aaatgttcaa gattatgagg aagccctaaa tattcaataa
     1441 tttggaactg actcatatca gataaatctt gttcatctat tgttctagtt aacatttcaa
     1501 ttgcaaacat attagcttca gcttctatac cataaatcat acaactaagg ttgtttgctc
     1561 taaaagctgc tgtgcaaata cctttatgga gtctaacgtg ggctatttca tgccataata
     1621 caaatctttt catagaaggt gataggtttt gattaattaa tatcacataa catcttttat
     1681 tgtgtatcgt ttgtcctaat gttttattcc ctaaatcagt ttcaattaaa tctatatcag
     1741 aatatttgat tattttatat ggattaatcg catcagatcc aaactctaca aataattttt
     1801 ctatttcttc taatatccag tatttgttta aatgcatacc aaagcccacc tattgacgat
     1861 attttttagg agtgaatttt ttctttgctt taactttggt taaggcaagt gcaagttgaa
     1921 tggcatcgta taatttttcc ttatcttcat cgtctaaagg ttcaccataa taatttgttt
     1981 cagcatctga attcaagcct tcaagtaatt tttcagcttg taaagcaata tcttgtttat
     2041 ctttttctgt taaatcataa taatggcgtt tatcagtacg tcctaaaaga taatcagttg
     2101 atacattaaa gtaatctgca actttttgta ttttatctcc agatggagta cttttattcc
     2161 atctagacat gcttccattt ccgaaattta actttctttc aagttctgcc aacgtcattg
     2221 aacgttcttt taataagatt tttatacggt ctaatagcat aggatatgca ttcctttcaa
     2281 aataccgaca aaaaaagtat ttttctgcaa attatctatt tacaaataga gaatttgcag
     2341 ttatactagt tttgtaagca agatatttac ggcatacaaa gactaaaagc aataaactaa
     2401 tagtctcccc agacatcagt aagctcgctt tttgtgcgct gtattttgta tgcttacata
     2461 atagcatatt tgcagttttt gtcaaactta ttagacaaaa atattagaaa atattcgata
     2521 agggggtatg aagcatgact ttaaaacagc aagtattaat tgctttagta aagaaaggtt
     2581 ggagtcaaag agagttagct cgacgaatgg gtatatcaat tacttattta cgagatatct
     2641 tcatcgaaaa aagaaaacct aaggaacgtt taaaacaaat cgaagaactt ttggatatca
     2701 agttagaagt agattctaat gatcagccat cagaacagga ggcgtaaaaa tggtacaacg
     2761 tttgagcaaa gcggagttta aagagaaata taagtattct gaaagtactt atcaaagaag
     2821 aatgaaggaa tttaaaaaat cacgttttag tgaggggtat aacgcagtta cttccaaaga
     2881 aataacaatt gatgtcgatt tatatgaaca gtttagaaca tggcgttcta aaaatcgatt
     2941 tagagttaga gctgtttgtt aatagctaaa aaatctaaat tcaccacttc tgaaaagagg
     3001 agttgctgct ctcctttcaa gtttgccaaa gtccacgttt tttcattttg gcaactcctc
     3061 ttcttggagg tggtgacggc gagagacgaa ggagggatga catgaaggaa gaatcaaaaa
     3121 tagggatttt gaatgagaac aattacacaa gattaattat tgaaacagaa gaagggaaaa
     3181 aagtagcaga agttacattg accgatgcaa ctcctgctga cggttatcgt attcgattaa
     3241 ctcctaaata tgattaacct tttggtgggt gtggatcgtt tccgtgacta tcacggcttt
     3301 gaatttttcc atctctgcca tgaataaata gctcagatcc ttgattttta gaaatctctc
     3361 tagcgatttt tactgcttct gattttgtat tagtatgtgc agtcgcttta gaatttccag
     3421 cacctttgac attccaacca ccattggaat taggtacaac atgttgattt tttcccatag
     3481 ttttcacctc catttctata gaaatatttt atcaaataga aatggagaaa ttcaataaac
     3541 gaaaggagaa gtgatatggc atataccttg caacaagaac atcaaattct cggtttgatt
     3601 aaacaacgca ggaaacaatt acaagatgac cgtgcagcgc ttagaaaagc cgatgagcta
     3661 tcagataggc aagctgaact aattgcttct gaacttgagg atttgagaat gctagaaata
     3721 aaaaataggg agattagatt atgaagaaga cagacacact ttttatagga ttcattttgg
     3781 ggttattagt gattgtagcg caccaaagta ttatcggggg aagcttgttc gcagcattga
     3841 tggttttaat caatctgctt gattcaaaag aaaggagcaa ctatggcacg agaagaagcg
     3901 ctaaaaatcg gtaaagtgat tgctgataat cggtggggaa atagccgccc tattatttta
     3961 agcaagcaac atatcgaaaa gcaaaaagca tggcaacaaa taaaaaagtg actctgccag
     4021 ccagcaaaga gtcacataca aatttataaa actaggagaa ttatatcaca tgaataagaa
     4081 aattgaaaat cttatcgaag aattgaaacg tgaatgccaa aagcaaggtg tttctattat
     4141 ttgtacagcc caaaaagaag gggaacttaa aagtctcgtt tatggtgaga caacagaaat
     4201 tttactttgt cttgctatgc aagaagaaca tttagatgaa aatctcccat tgtcagcaca
     4261 tattatgcgt agaattgctg tggatgctta cgaacaagcg aaaaatgaag aagaaaatca
     4321 accttcaaat catacttttg ttattaataa caaggaagat ttagctgatg tgatgactcg
     4381 tattctcaag ggggaatttc aatgatgaat gaaaaaacaa ttgatctact cattatttta
     4441 tttttcacgt tagtgattgt agcgaaaagt tatgtaatct ttggcttgtt attcgcaatt
     4501 accatgcttg tgctttgcgt gttagcaagc agaaaagagg ttaaacatga acgagttagc
     4561 aaatcttgac aactatttaa ctgatcctga ttatgctaaa ccaccatatg aagcaccaat
     4621 tgatgaggag gatgaagatg agtaaatcta ccttagaaat gagccatcaa gaatggcttg
     4681 aagaccgtaa gaaaggcatc ggaggttcgg atgttggaac aattttagga ttgaataaat
     4741 ggaaatctcc ttatcaacta tggctagaaa aaacaggaca agtagtactt gaagaatcag
     4801 gaagtgagcc cgcttattgg ggtaatgttt tagaagaagt ggttgctaaa gagtttcagg
     4861 aacgtacagg caaaaaagta cgcagaagaa accaagtatt tgaacatcca ttacatccat
     4921 ttttaagagc aaatattgat cgggaagtag tgggagaaaa tgccattctg gaatgcaaaa
     4981 cagccaatca atttctcggt aaagaatggg aaggcgaaga ggtaccgctt agctatctct
     5041 gtcaagttca acattacatg aacgttctaa acaaagacta ttgttacatc gctgtcttaa
     5101 tcggtggtca aaaatttatc tggaagcgga ttgaacgaga tcaagagctg atcgatacaa
     5161 tcactgaaca attagtagag ttttgggaaa caaacgttct tggaggtatc gagccaatta
     5221 ttgatggtag tcaagcgaca gctgatttct tgaaagagaa gtatgcagat gttgaagacg
     5281 ttcaaacgac gttaccaatt catttcgatg aactagttga acagaaaaac gaactcaaac
     5341 ggactaagaa agaaattgaa tcagctatcc gtcaagtaga caacgagatt atcagcgagc
     5401 taggtaaacg tgaagccagt atcggtatca ctcaaaaaaa catcatcagt tggaaatttg
     5461 tccgtacgag acgtatgaac tcgaagaaac tagcagagaa atatccagat gtcgcaaatg
     5521 atgaagagat ttataacgtt actgaatcaa gaaggctaac cgaaagggag atcaaataat
     5581 atggcaacaa atgaatcgtt aaaaaatcaa ttggcagcaa agccacagaa acaagttgca
     5641 ccaggtcaat taggacttaa agctttgatg aatacaccaa caatgagaaa gaagttcgaa
     5701 gaggtgcttc atgacaatgc taatgctttt atgtcgaatg ttatgactct tgtatctaat
     5761 gacagttatc ttgcagatag tgaaccgatg tctatcatga gtggtgcgtt aactgctgca
     5821 acattaaatc ttgggctaga taagaattta ggttatgcat atttagttcc attcaatagt
     5881 aaaaacaagc aaacaggaaa atgggaaaag aaagctcaat tcatgcttgg ctataaagga
     5941 tatatccaat tagcccaacg atcaggtaaa tacaaagcat taaatgtgat cgaagtttac
     6001 gaaggagaac taaaaagctg gaaccgactg acagaagagt ttgagtttga tccaaatggt
     6061 agaacgtctg atgaagtcat tggatatgtt ggctatttcg agttactgaa tggattcaaa
     6121 aaaactgtct attggaccaa acaagaaatc gaagctcatc ggattgctaa caataaagat
     6181 cgcgataaga caaagttaag tggtgtgtgg gcatctgatt acaatgcaat ggcacgaaaa
     6241 actgttttga gaaatcttct ttctaaatgg ggaatcttgt ccatcgaaat gcaagaagcc
     6301 accacatcgg atgagagagt ccaaagggtt caagaagacg gcagcattat tgctgaaaca
     6361 gaagttgaag aagatattcc tgaaagaaaa gaagcagagg ttatatctga agaaaatgaa
     6421 gatgtacaaa ctggattatt tgatgcatct aatccgccgt taaacaaata atgagggagc
     6481 tttctccctt gcttttctag aggagaaata cgaatgaaca caggatatgt caaattacat
     6541 cgaaaagtga tgaattcatt cgtttggacc aatccttata tgtataaatt atggaacttg
     6601 tgtttgatga aagcgagtca tgagaatcgc aagatacttt ttaatggaaa agagatacaa
     6661 gtgaacagcg gagaattcgt cacagggcgc gatgctatca catctgagat gaacgaaggc
     6721 gtgaaacgtg aacatcaagt gaacagcggt tctgtatgga gatggctaaa acaatttgaa
     6781 aaaaacggaa tgttgaacat caaatcaact acgaaataca gcgttatatc aataaaaaac
     6841 tggtctttgt accaaagcag tgaacaacaa atgaacatca aacgcacaac aagtgaacaa
     6901 caagtgcaca caaacaagaa tgaaaagaat tataagaatg aaaagaataa taaaacatca
     6961 tcgtcgcaac cacgcaaaaa gcgtgtttac gacaccgact cagtttacta cattctcgcg
     7021 gaggagttat tcaaacagat ttgtcagaat caggaaatca aaaagccgaa tctgcaaagt
     7081 tgggcagatg acattcggaa aatgatcgag atcgacaagc ggaccgaaaa ccaggtacgg
     7141 ggaatgattg aatggagtca gcacaatgtg ttttgggcat cgaatatttt atctgctaaa
     7201 aaattgcgag aaaaatacga cacaatggca gcgcaagcaa atcgtgatta taaaacaaaa
     7261 caaactaaaa cgcttgaata cgagaaattt agcacagatg agttgcctat ttgagaggag
     7321 gcgtaggcat ggaaactgtt ggggaaatca tggaaaagct gatacagaaa gtgcttgtcc
     7381 aacgtggcga atgtcctgaa tgcggacagc ctttgtatgg atggcgtacg aagaaccctg
     7441 atggctcaga acgttgtaag ccaacctgta tgcaatgtgg gtataaagca ttgcgagttc
     7501 aggaagactt acaaacagaa cgaatttaca acgagagcct gaaagcaaga gcaatcaatt
     7561 ttttcaaagg tggttctgtt gtgcctaatc aagcgttgtt tgattgcaca ttgcagaatt
     7621 atcaaattgt cgatcaagaa acaagacaag cggttgaagt aaccaaacgc tttgttaatt
     7681 cagtcttgtt aggaaatcca agtcaccttg ttttaactgg aaaacaagga acaggtaaaa
     7741 gtcacctagc gatggcagcg gcttgggaag tcttgaagcg atcaaactac gataaaaaaa
     7801 tcttatttat cgggttacag gaaatgctgg atcaaatcaa attttcgtac aacaatcctg
     7861 aactcagaaa aacgattgag ggatcgttga ttgcagatat caaaacagcg gatttagtca
     7921 tcattgatga tatcggttca gaactaggaa aagatgcatc agatagtcga gcgtttggca
     7981 taaacacgct aaattcgttc ttggatgcac gacagaacct agcaacgatt atcacaacga
     8041 acttgcttgg tgaagaactg aaaaaagctt acggtacgag aacaatatca agaatgtttg
     8101 tcaactctga tggatttacg atggtatttt ctcaaacagc agacaagcgc ataaaaccag
     8161 tcaaaggagc gatcgcatga atttgactaa acaagaaaaa agaatctgtc gtcagataat
     8221 gttgcaaatt ataggtgatc gtgacatgga cgaattatct caacaagaga gtcgaatggt
     8281 tcggaagata agtaagctaa ttatttatcg ggatacagaa agatttctca ctgttttagg
     8341 taacgtctac gagaatccag agttattgga ggtagagtaa ttgccaaaaa tattagatgc
     8401 atgttgcggt agtagattgt tctggtttga taagaacaat tctgacgtaa catttatgga
     8461 ttgtcgtcag cagtatgaag aattatcaac aggtcatgtg atcaatgttg atccagatgt
     8521 ggtcgcagac tttcgcgata tgccttttga agatgatgtg ttcgatatgg ttgtatttga
     8581 cccgccacac ttaagacatg tcggcgaaaa ctcatggctt gccaaaaaat atggaaaatt
     8641 agacgaactt tggccagaag acatcaggca aggttttgca gagtgtatgc gagttttacg
     8701 accttcagga acattaattt ttaagtggaa cgaggaacag ataccacttt ctgatgtgtt
     8761 agaggctatt ggagaacagc cattgtttgg taataaacga agcaaaacac attggcttgt
     8821 gtttatgaaa aaattcagct aacggaggaa acaaaggagg aaaagtaatg aagattgtat
     8881 taaataaatg ttttggtggc tttgggttga gccatgaagc aaaaatggaa atttttaaaa
     8941 gaaaaaatat tgaagtattc ccatacatca ataactttag ctatgactca gatgatgaat
     9001 acacgagata cacaggccaa aagctaggtt cgatggattt tatctactat ttcaaaaaag
     9061 acccgaaaat cgacaaagtt acaggaattt atagcgaaat tgaccgactg tacggaattg
     9121 ctgatgattc cagtttttca agtgattcaa acagaggtga taaggacctc gttgctgttg
     9181 tcgaaaaact aggaagtgag gccagtggac catatgcaag tcttaaagtc gttgatatac
     9241 ccgatggggc tgagtgggaa ataagtgatt atgacggcgt tgaaactgca cattatggtt
     9301 ttcaaacagg tagtatttag tccactaatg acaactaaag aggaggcaga aggatgagtg
     9361 aagatgaata ctttgaacag tagtctatta acgacagaga tttttaactg gaaaggggtg
     9421 tagtcatgga cgcatcggaa gtagtaaata aaattaatag tctcaaagag gttttcggag
     9481 acgtcgaagt agtgataaac gcacaaggct atgacaacga attttttaag cagattaccg
     9541 acattagcat tcagcaagga atggaagacg aagacggaaa ctttatcgat gaagtagcca
     9601 ttttagtgac ttgcgagtaa gtaattgaca gctaaagagg aggaagcgga atgaaactaa
     9661 aagacggatt ttactccagc ggccacggca tcggcggttt aatgctagat atgccgacaa
     9721 agaatcctaa aacacgtaag aaaccaaaat tcaaagtcgg tgacatggtt cgctgcgaag
     9781 cagaaggatt catctatcca tttcgtggat atgtagaaca cgtctataat cactcagcaa
     9841 tcattcgcat tgaaaacacg atggaatgtg ataagtggtt agcgaaaagc aaagagaatt
     9901 tagcagtggt gagattggtg gacatggaag ttataaaatc ttaattttgc ttttttacaa
     9961 ctatcctaca acaatgagcg ttattccaca actggaagga gaagaggcaa ttgtgaacat
    10021 tttagagaat atagatatta agcaaacaag gaaaaatgct agacgattac taaaaagata
    10081 cagaaattta gaacgtttgg tcggaccagt gaaaatagac ttttccgtga tgactgttac
    10141 caaaaatttg aaattcacaa ttgacagtca aaacgaagaa atcattgaag cgataagtac
    10201 tcgagattcg gttatcgaag cattaacacg gctaagtaga atccatttcc aggtacttta
    10261 ttatagttat tgttttccta ataagatgtc aatgtatcaa ataggagaaa aattaggata
    10321 ttccgataga actatcgaga gaatgaaggc agtagctttg gttgaatttg ctgaggcgta
    10381 taaatcagga gaactcattt cacgtacaaa ataaaaaaag tcggattcct ccgactatga
    10441 ataatatttc cgacataagt attatatcat aattggggga atcagaggat ggtacttttc
    10501 gatgtaaaga aatatgagac accaagcgcg aaagatgttg atatggaacg cacaaaacat
    10561 aatgtcgctg tgtttctttc agcatatcta tcagctagat gtagagtagg gcaacatcga
    10621 gaaccaaaag tgacagcatc ttattccttg gttccacctt ctacagctga tcatatattt
    10681 gaagcagaaa gaatgctgat cgataaagaa gaagcacagg aagaatttga gtatctgcat
    10741 aaattgtttg ttcgaggcta ttcagcgata cagcatccgc ataagcctga tgtgactgaa
    10801 aggcgcaaga agatattcta tgatcgttat atcaatggtc tgcccattta tgtaactgct
    10861 caaaggaata atactagcga agaatcggtt aaagtagaat caaacagaat tatcatccaa
    10921 tttgcttcat cgttagaact ggttgctttc aagtagccag tttttacact ttttataccc
    10981 ttttattacc aatttggttt ccattttata ccttttttat accaatcact tacctattca
    11041 acgttgtatt atgatagtgt cgaaaaatta ggaaacagga tcgacaaaat aaaatgtaag
    11101 ggaggaaatc tccctcatcg tttaattaag cttcgatagg cagcaacgga aatattaaga
    11161 ataaggatgt gaatttcaac tccttctaaa ttgttcttat tatctatcat ccgttgctgt
    11221 ctattgtttt tttaattatt cacacgataa ctaaaggtaa gtgaagagaa atgattccat
    11281 taataatttc aatttttgcg ctttgtctta atgtatatat gattggattt aaaaatgggc
    11341 aaaataaaaa atagtagcag ccaagaataa ttttatagtg tcactgtggc ggaaagggta
    11401 gacgctaagc atgtgtgcta ggtcaatgct tcggcaacca tgcaaggttc gattccttgc
    11461 cagtgacttt ggcaaccgag gcatcggcgg tttaaaaata taggggtgcg caatttcgta
    11521 cgcgttttgt gcatcgtgta ggttgctatt acataactgg ttaggttaga ttgagatttg
    11581 ggattcggta caaatgaatc gtcaaatgtc tcaagcacag gatcggaaac gtccctgcct
    11641 gtgcattaca tattagatca ctctttgagt ggtctttttc tttacataaa ggaggctaca
    11701 taatgagaaa ctactggtat gtatcgctaa ctaatgaata tcctcgaacc attgatgatt
    11761 gttcagtgcg tgttgtgcgt tctgtacaaa tcaaagggaa gtactctatt gtcgaaatgg
    11821 ggagagaagc agaaccatgt gagattgatg cgtgcaagct cgtttattgc ggtcatggtt
    11881 tctatgatga accaaacatt caaaataata ttaacaagaa tttgagggat tagaatgcaa
    11941 gaaatggctt aaaaatctcc aatcaggaca aatcaagtta gacaaagttt ccgatttaaa
    12001 gatattgatt gaagctgatt taatgctaaa agatattgaa aattagaaaa caaaactcaa
    12061 cctaaacaga atgtgaggtg gtgtgtattg aatggcaaga caacgtgatc caagacgtga
    12121 tgaagccaaa agaatttggt tagaatccaa cggagaaaag cagttaaagg aaattgcatc
    12181 tgaattaaat gtttcagatt ctcaggttag aaaatggaaa tcgcaagaca aatggagcgc
    12241 tgaattgatt agtaacgtta ccaatggcaa aagtaacgtt actaatcaag gtggcgctcc
    12301 tattggtaat caaaatgcta aaggtaacaa aggaaatagc cgagcttctc cgccagtggg
    12361 taataaaaac gctttgaaaa caggtgagta tgaaacaata ttttttgaca cgttaaccga
    12421 taatgagaag gacatctatt ctagtttgaa tgatgatcct tcttttgctt tgtccgaaga
    12481 aatacgactt cttaaaataa gacaacttcg aatgatgaaa agaatccaac aagctgaagc
    12541 tggactaaat gatgaagaag tcgaacgatt gcagcagcta agaaagatta aaactccgat
    12601 tgaaaaaaat ggtaaaaagc tagaaatcaa gcgtgaggtt atgcaagatg tgcagattag
    12661 cagaaaaaaa catcgcaaaa ttgatgatat tctttcaatt gaagattcat tgactcggat
    12721 tagcaaccag ttagctaaag ccatcaagca aatgaatgaa ctttatatga atgaatacag
    12781 aactgattta attaaagctc agactgataa gatccaagct gagacaaatg aaattggcgg
    12841 aaataattca ggtgaagaaa tagaagaatg gaaacaggca gttttaaatg ccgcaaacaa
    12901 acgggcggtg aaagaaaatg aataatgaat ttattccttt tgctgatatt ggttctgcca
    12961 ttgattatta ctatgataaa ccagtagctt tttgccaaga tattttgcat ttgaatcctg
    13021 atgaatggca agaaaatgtt ttaaatgatt tagctgaatt ttcaaaggtt tctgttcgtt
    13081 ctggtcaagg agttggaaaa acagcattag aagcaggagc aatactttgg ttcttaacgt
    13141 gtcgacccta cgctaaagta atagcaacag ctccgacaat gaagcaactt tacgatgtac
    13201 tttgggcaga ggtagctaaa tggttaaatg atagcttgat caaaaactta ctgaagtgga
    13261 caaagaccaa aatttatatg gttggtgatt cagagcgttg gtttgctacg gctagaacag
    13321 cgactaaacc agaaagtatg caaggttttc acgaggacca tatgttgatt gtggtagatg
    13381 aagcttctgg tgtgtctgat ccaattatgg aagctattct tggtacgcta tcaggttttg
    13441 ataataagct gttgatgtgt ggaaacccca ataatattga aggtgtcttt tatgattccc
    13501 ataattcaga ccgtgataaa tacagagttc ataaagtatc aagctatgat agtaaacgta
    13561 caaacaaaga caatatagaa atgattctta aaaaatatgg aaaagaaagt gatgttgctc
    13621 gtgtccgtat ttttggagaa tttccgaaag gtgcgttgga ttcatttatc agtcttgaaa
    13681 cagttgaatt ggctacagaa aaacaaatta gtgattcttt agtcaataaa acaaaggttg
    13741 ctcatattgg tgtcgacgta gctcgatatg gtgatgattc tacgattctc tttcctagaa
    13801 ttgctaccag ggcattggag tatgagaagt attcaaaacg tagcaccatg gaaacaacag
    13861 gatatgtcat caacatggcc aagaatctaa tgagtcaata tccgagtatt gataaagtga
    13921 tgattaaagt cgatgacact ggtgtcggag gtggtgtaac cgaccgccta gaagaactta
    13981 tagaagacaa acattatcct tttgaggtgt ttggagtgaa taacggttca acatcagaag
    14041 acgattttta cgataattta ggtactcaac tatggggaaa catcaaggaa atgttagaag
    14101 aaaatatgac agcaaatctt aacggagaac agcctgttat tgaattgcct tctgatagtt
    14161 cgttaatcaa agaattaagt actcgcaaat tcaaaatgac aagtagaagt cgtatacgtt
    14221 tagaaagtaa agatgatatg aaaaagcgaa atattggtag tcccgatatt gctgacgcac
    14281 tggctttagc gttttatgag ccaccaagtc actatcaatt tattcaattt taggaggtga
    14341 gcttttgatt agtacagtat tatctttaga gagatataag aagctacgtg ttaaatatgc
    14401 aacacaaatt gaagatggaa tgtttgatcc gaatggtttt atagaagata tgaaaccatt
    14461 ttttgctgat cgcgaaagaa aatatctagc ttatactagc gaaaagaatg aaatagataa
    14521 tagaccaaag cctaacactg atattgtaaa agttaataat aaacttcatg ctggtatgta
    14581 ttcaattgtc gtagaccaag cagtcaatca ttttactggt atacctatca aatgggatta
    14641 cgatgtatcg gaacaaaaaa gaacactcat tcaaagatta aaagataaat tcttaaaaaa
    14701 tgatatagaa cttccgacag ttccagaagc ttttaacaaa ttaacaagca atcttgattc
    14761 catgagattc gcaatgcttg attctgaaac tgcaactttt caaggagctt gtggagtagc
    14821 tttccgattg ctagagcctg tggaagaaga tgatggttgg aagttaagag caagtaatat
    14881 tgaaccttgg agagcagaaa gatatggaaa tgccggaatc tatatcaaag aaaagtatga
    14941 ctcttaccag aaaaaatttt ttcaagaaat gaaagttatg acaagaaata aaattctgac
    15001 atatgcttgc tatggtgatt tgaattttgt tacaagcgga acgttcaaaa aaattgatga
    15061 gaccgataac cctttgggga cgattacctt ggcagaattt aaaaataata cgaatcgtta
    15121 ttgtgatttt gaagtagctg aggaaattgg agatgcaatt gatcgtgctt tgtctgatca
    15181 acaaaacgaa atcgaacaat ttaagcttgc gtacatgctt gttactggca caacaatgag
    15241 caaaggcact gctaaagaaa tgatgaatca gctagggatt atcaacttaa aagcccctac
    15301 tgcaaaagct gaatatgtca caaaaaattt agcaaaagat ttcaatgaat atcatatgga
    15361 tctattgaaa aaacagtttt acaccatttg taaagcaatc gattttaacg atgaggtgtt
    15421 taaatcaaac agttctggag aagctcgcaa gtggcaaatc attagcctag aagcgaaaac
    15481 aaatactaaa gagcaatatt ttagagaagg attgaaagaa tgcgcagaaa caattgctgc
    15541 ttttcttaag tttcatgaca aagtagaaat tgagcctgaa aaaattattt ttactttctc
    15601 tagatctttg ccaactgatt taagttattt agctgaagct ttacctaaac ttgcaccata
    15661 cgtatccaaa cgaactattc agagccaaat tccatttgta acagatgttg attatgaaaa
    15721 tgaaatgatg gaattggaaa gtggaagtgc ttatccagat agtgaataca attttggcgg
    15781 aggtggcaat agtgacgata gaaacgaagt attggaccaa acgtcgagaa ctggaggatc
    15841 aagcaaggct caaacaagaa aatcagacac ttaaaaaatt aactagtgta tttcctgaag
    15901 cactgaaaga gatacaagca aaactattat cacaagctga cttacacaat atcacttatc
    15961 cagaaatgat ggagttttac agtacaagta atcagaaaaa atatcgtgaa tatgtggaaa
    16021 aaaattataa gtcattaaaa atgtatgatg caaaatacaa agagtttatc gatgaatttt
    16081 ttccaccatt tgactatgca aaagtcaatc gcttattaca aatacgatca gatgtattta
    16141 aaattcttgc agaatatgcg atggatgcag atgtgaatca atatttttct gatcgcttag
    16201 aggaaattct tcaaagaaca tattcttcta atgctaatgt ttttgttcaa cttttaaacg
    16261 ttgatatacc aaattattta ccagaaaatg aaattaaaca ttatttgaac tatccatggt
    16321 caggaaagac attttcaaga agactttggg gaaatatttc atcgcttgaa cagaaactct
    16381 ctaatgctat tgtaaaaagt gttgctagtg gagaaggcgt tatacacgca ttaaacacca
    16441 tgagattaga ctcagaaatt tgtgacatgt ttaagttaga agaatcaaag tataacaaag
    16501 cgatagaaaa tctcgttcga acggagtatg caaaatttgc acaagatggt attgaaaaat
    16561 catatttaga aacaggtatt gaggaataca acgtattgac tgcaaaagat gagagagttt
    16621 gccggatttg tggaggaaag gcaagtaaga atccctataa actgaaagat gctgtcatag
    16681 gtgaaaatcg agcacctttc catagtcgtt gtagatgtac ggatgttcct aatttaccaa
    16741 aattaggaaa ggatattgat gaagaatatg accgtttatt tggcgattta ttagatgagt
    16801 ttgcacatga ttcttttgga attaatttga aacggaggaa gtagaatgaa agattttttt
    16861 gaagcagtac taacaattaa tgtaaatgct gatattgcag aagcctacaa aacagctatt
    16921 gagtctgaga accatcctaa tggcttgaga gaccattgga atggcaatta tgcctacgtg
    16981 gttattggcg atcaaactgt taattatcaa gataatactc cagttgataa gaataccgtt
    17041 aatttaacga ttcaattatt atctcattca ttaccaaatt taaaagaaac agttgattgg
    17101 tatgaaaaga tgggatgtat tgttgttaga actgactaca aagaaggaaa gtctagtaat
    17161 taggcttttt tattttgtcc gaaatgacgt taaactagcg caatactggg cttggttgaa
    17221 tggtggggcg caactattaa aactcaaagc aatgcggggc gtgaaaacga atcgtggggc
    17281 gaaaggagaa tgagcatgaa acacaaatca ttaatgccaa tgaatttgca atactttgcc
    17341 gaaggtgacg atcaaaagtt ttcttttgat gacttcaaat cttttgtgga atccaatgaa
    17401 gaagctcaaa aatttattca gtcacaatct caaagtgttg ccgacaaaca attggaagct
    17461 tggaaacaaa ataacttaga taaaattaaa caggatacca tcaaggaata tgaggaatct
    17521 aagaaaaaca agtcacctga gcaaattcaa ctggaaaaac tacaagctga atttgaagca
    17581 gaaaaagcgt tgcgtgtgac aagtgataat aaagcatttg ttgcagaaca aattgctgga
    17641 ttagaactag atggagagtt aaaagagtct atttctcaat ttatgctaaa taatcttgtt
    17701 agttcggata cagatttcac taagaatgct gttgaaggtt ttacaagtgt tttgaatgca
    17761 attaatgaga aacatgcaga tgcattaaaa gaactacaaa tgaagtctgc atttggtgga
    17821 actcaacaat cgaataacca ggttcagcag aacaatgaaa cattaacaaa tccagaagaa
    17881 caattaggac aaattcttca acaatttaac taggagagtg aaaaattatg aaaaaaacat
    17941 ctttaaataa tttagagtat ttggatattt caccagcgat taatgctatg caagtaccaa
    18001 atacaccttt tttaagctat ttacttggtg ctggaaaaac agagccagca aactcgacag
    18061 aaattaaatg gcgtgaatat gatatcaaca acgatgattc ttctgaaaaa cttgagggcg
    18121 gagaatatcc agatgctgaa tcaggtcgaa cttggtttaa caactatact gaaattttta
    18181 gaaaatcaac ctctgtatct ggtacattag atgctattaa tgtgaatgga gtcggaaatg
    18241 aattaactaa tcaagtagca ctacgtggta tggaaatgaa aattgatttg aaccgaaaat
    18301 tgattactgg tgtaaaagct gatgaaaatg gttctaaagg tcgtcgaatg aatgggattt
    18361 tgaacttgat caattcagca aataaggcag aaacagccac tgcgggtgca gtaacaagaa
    18421 aagatatcga tactttattt aaattgatgt atgaaaaagg ttatatggga gaaaaactat
    18481 gcttgatttc tccagatatg caggagttaa tgactgatga gttagatgga aaatcaacaa
    18541 aaattgttca gttcggggaa agagtaactt ttggattgca aattggaaat atcgtgtcta
    18601 attacggtac aggtattgct ctactagaac catcattgcc aaaaggaaca attgccgcaa
    18661 tcgatactaa ttatgtgaaa ctacgtccat tacgtgaatg gagagcagaa gaacttgcaa
    18721 aaacaacgga ttctagacgt atcggtcttg taggtgaata ctctcttgaa tacaatgctt
    18781 caaactctgg ggcaatttta aatttaaagt ctgaataaaa gggagttagt actccctttt
    18841 ttgataggag gaattacagt ggtaaaaaaa gatgaaacta aaaaagatga agtcgtgaaa
    18901 tatagagtag gtaaaactaa aaattttgtt gggtttgttc atcctaaaac tcgtagattt
    18961 atcacagcag attcaaataa cgaatttatc atttctatag atgataaaga agcaattgca
    19021 attttggaag atgcaattga tgttaatgaa atttaggaag tgatctgatg gatgaatcgc
    19081 taaaaacgga aatcattgag tctacaaaag aagattttcc agatttgagt gaagaacgca
    19141 taactaattt attagaaata attttgctag aaattgaatc atacaacact tgtaaaaatg
    19201 atatttcatg ggaaaagtta aaaagcgtga ttagtgaagt gttgtataaa ataataaaaa
    19261 atgaatcaga aaaaacagta tcttcagtta gacgtggcga tacaacgatt agttatgctt
    19321 caacaacaaa tgatgttagt gagttacttc taggctatgg tgatttgata cgaagagtta
    19381 ttggttgtgg aggattggag tttttttaat gaatgaagca gatattttag aaactactta
    19441 tgaagatagt tgtattattg aaagactgac ggacattgaa gattctaata caaatattac
    19501 tattcaagat tacaaaaaag tatatgataa tcctatttct tgcgctcttt cacaaggtca
    19561 aatcgatgga ctagcagtca tagaagatgg agagatggta aatgtttcaa ctgacacata
    19621 taaattattt gttcatccta agattaaact aaaaaaagga gatcgaataa caataactca
    19681 aaaggccagt ggcttaattt tttctctatt tgctactaag cctttttact atcctagtca
    19741 ttgtgaagtg aatttgatag gaagtgagaa aaatgggtaa tctcaaatat gaatcaaatg
    19801 cagaaaagat cattgagaat tttaaaaata tgactgtaat tgctcaaaaa gaaggaatat
    19861 ccttcgttaa cgattcaatg aataaagtcg ttagtttagc taaaccatta actcctgtaa
    19921 aatcaggtaa tttaaggcga ggatatcgtg tagtaaaagc tagaaaacta tcaagcggtc
    19981 gaattgttgg agaagttata aacaatgaac attattttaa atatgtagaa gaaggtcata
    20041 ggactaaaaa tggtggcttt gtcaaaggga aattcatgtt aactcgtgca acgaatcttg
    20101 caaatatgtc ttatattcct cgaagattta aacaaatggc aataaaaatc gttaagaaag
    20161 gaaagtaaca tgaaagatga aatcattgct gcaatcagta gcaaattaaa agaaatctat
    20221 cctgatggga caatatatct tgattcagtt atgcagtcaa ctaaagattt ttatttcgtt
    20281 ttatcagtaa tggaatctgg aactgaaaat gtaggaattg atattcaaaa tgtttctttc
    20341 ttaattgata ttgcattgat tgataataac cctaatagaa atttaattaa tgaattagtc
    20401 tcacgttgtg ggactttttt taatacgatt acaatcgatg agcaaatatt atttccaaaa
    20461 gcctatttac ctgatgaagc agatggtgtt caacatattc gttttacatt agaatttcca
    20521 caatatattg aatggagtga aagataaatg ggagaaaaaa gaagtaaaac cggaattatt
    20581 tctgtcgaaa aacctacttg gtttcctttg gaagatgaga cagggaattt tccggtatat
    20641 ggtactgcgt tgccaatggg aacagcagta agtatcaaac caacagctaa ttatgaaaca
    20701 acacaagatt atggggattc agtggttcaa gatcaattta cagcttttgg tggtgcagaa
    20761 gttgaactgg aagcaaatgg atatactcat aaagttttat ctacaattac tggagggaaa
    20821 attgttaaag gtggtgcctt gcgttctgga gaagatattg cgcaagatgg tgcgtttgca
    20881 tatagacgta aaaaatcgaa tgggaaatac cgttatacgg tcttttataa aggacagttt
    20941 gctctagatt cagatgaaac atcaacgatt gaaggaagta aagtaagttt tactcatcca
    21001 acttggaagg gttcatttgt agatgtacca ggacttggat atatgtattc agttgatgaa
    21061 gatgatgaag gcgtggataa agcaatgatc ggaaattggt ttacaaaagt agcaattcca
    21121 attgaagaag cagaactttc aggaggtaca gaataatgtc aaaatatcaa acaacgatta
    21181 aattaacgaa aaaagacgaa gaaggtaaat atgagcaagt acaatttaaa tctgctgaat
    21241 ttttaccagg aacagttgta gaagatgctg caggagttat ggaagaaatg caaacagcga
    21301 ctgataagca atcagttaaa aaagctttaa gtcgtgctta ttcatttatt gcagatactt
    21361 tatttgaggg acaatttact ggtgaagatt attgcaaagg aattgatgct cgtgagattg
    21421 cctcattgac aggaaaatta ttgaagtctg ttactgcagg ttttgatgaa acttatacag
    21481 agacgaaaaa aaagtaagtg aggcgctcaa gtcaccttca tttaagtatt cgattactta
    21541 ccgagaatta gatataaaga cgcaattact cgaagcaggt tggacgttac cagaaattga
    21601 acgtactgac ttggatgagt taatgcgtct ttttgctttt agagatgcgg taaaagagca
    21661 tgaagatgtt gagtactatg ataatttcac tcaattttag gaggtgatac tttgaataac
    21721 gatgacctaa ttctgaagat gatactagat gaatctggtt ttactgccgg tatgaataat
    21781 gctgtcaaaa agttgaactc ttttgatgaa acaatcgaaa gaaaaagtag aaatagtggc
    21841 agttcattag gtagtatttg gaaaatattt gctggaagtt ttctagctag cggagtaact
    21901 agaatcgtag gagctggctt tgatctaatc aagggttcca taagtggagc ggttgatcga
    21961 gtagatacga tgaataacgc tctacgaaat ttccaaaata tgggatttag taattcagaa
    22021 attatgaaga atatcggaaa gaatgggctt ttatctcaag gtattcaagg acttcctact
    22081 gctttgaatg atgcgataag tcatgttcaa cttcttgctt cttctacagg tgatttaact
    22141 cgttcaactc aaatatttaa agctttaaat gatggaattc ttggtttcgg tggttcaact
    22201 gatcaagtta atgaagctgt tattcaatta tctcaaagtt tctcaaacgg aaaagtagac
    22261 gcacaaactt ggaactcaat gatcaacgct caacttggac ctactctttc tgctattgct
    22321 aaaaagatgg gaattacaat gggagatctg aaagaaggtt tatctcaagg taagatttct
    22381 gttgaagaat tccaaaatca attaatagaa atggatacca aaggtggcgg aggacttaaa
    22441 tcattaagtc aaatcgctaa agattctact aagggaatta aaacctctat acaaaatgca
    22501 aaaacagctg ttacacgtgg tgttggtgag gtaatagaag gattaaataa agcattagta
    22561 gattcagatt taggtggatt taagggaatt attgataaag tgggcagttc aatggaatcg
    22621 ttcttaaaag taattgctgc aaatattcct acagcagtat catttttaag taatttattt
    22681 aacgaaattc aaaaatttgg ttctgctttg aaattcatga tgccctttct tgttcctgca
    22741 gctaccgctt ttggagcgtt catgtttcaa cttaaaggta taccagcaat aataaaaagc
    22801 ttcaataatt ttaagaatgc cataattggc gttggaaatt cattaaagat tatgggggca
    22861 atagctgctg ctaatccatt tgttttaatt attggtgcag tcgttggtgc aatagctgtt
    22921 ttcggttact ttatggcaac caatgaagag cttagaaaca aggttatatc tatttggaat
    22981 gatgtgaaag attccgtaat tggtgtatta aaaaatataa aggactgggg aattgatact
    23041 tggaattctg ctaaagaaat ggcatcaaat gcagttgagg gtgtcaaaga tgcttggtca
    23101 ggaacaaagg aatggttttc taacacctgg aaaggtatta aggatggggc cacaggttta
    23161 tttgataaaa cagtagagac ttcaagaaat gcagtcgata gtgtaaaaaa tgcatggtct
    23221 aatatgaaga aatggttttc tgatacttgg caaagtataa aagattcagc cagagaaaaa
    23281 tggaatggaa tcaaaggttc tattatgtca gttgctggtc cattgattac aggtataaag
    23341 aatgcatttt tacatgttac tttttatcta gagaccttat ggaataattt agttgagatt
    23401 ggtaaaaacg tctttgagat tttaaaaaat gttatacttg cgccggtttt gtttattacc
    23461 tccatgattt ctggtggatg ggaagaaaca aaaaataata tgattgctgt ttggaataat
    23521 attaaagaaa gtgccataaa tatttgggaa tctataaaga atatatttgt aagttatttt
    23581 acaaatattt attttgctgc actcaatatt tggacagggt tcaagcttac attgataaat
    23641 atttggaatg aagtggtaaa tcaagctaaa tcgatttggt taaacataaa gtattttttt
    23701 attaatcttt ggattgatat aaaatatttt gcaattcaga aatggattga attgaagttt
    23761 tctattattc aaacttggat cgatttaaaa tataatgcca ttactacttg gaataatatt
    23821 aaacagtttt tcaaagatac ttggaaaaat attaaagata cggcatacaa tacgtggatt
    23881 tctataaaaa ataccatgat taatacatgg aataacatta aggactcttt ctggaatatt
    23941 gttactggaa ttgttaattc tgctgaaaat gcatggacaa atctaaaaaa tggtgtttca
    24001 aatgctatta atcgggtaaa agaaatcttt aattcgttaa gggaagtcaa tttatttgaa
    24061 attggcaaga acatcattga tggacttata aatggtgtaa aagaaaagtg gaatgctttg
    24121 aaagatacta tcaaaggtat tgcaggtaat atcaaaaatt ggattaaagg agctttagat
    24181 attcattctc catcaagatg gatgcgtgat atggttggta aaaatattgt tcaaggtatt
    24241 atcgttggta ttgataaaga gcaaagtaag ttagatcaaa ccatgacaaa tttagtaaaa
    24301 acaccgtctg ttcaacctgt agtaaatgga ataagtcacc taccaattac acaaacaaag
    24361 caaaatatat ctgctagtga aacaaaagaa attcatttac atttaaatgt ttatggagat
    24421 ttacctgatt caatggttcg gaagattacc acaaaaatta aaacagaatt gacaagacaa
    24481 atgaaacgag atgctggtgc agtaggagga acattatatg caacttaaga gaggacaatt
    24541 ttttattaat caacattatt cttctgaatt taatgtgtat attcaaaaca ggcctgcttc
    24601 tgtttcagct agtcgagtaa ttgaattgag agagcgagaa ggaaatgatt ctatcattat
    24661 tgataaaggc tattacaaaa atgtgactag aaagattgag tgttactata aagcaccttc
    24721 aattgatatg gtgcaggagt gggaagatcg aatcactgaa tggttagata tgtcgtctta
    24781 tagtgatttt attctttact atgatgaaca atatatttat caagctgtag taatagaagg
    24841 acctgaattt aaaggaacaa gaaaaacagg aaatattgtc ccttttgaat ttacagtgag
    24901 tattcgacca tttaaggaaa attacaatgg tagatttact attcgacaaa cagaaacttt
    24961 tgaaatttat aacccagaga agtattcttc aaaaccgctt attaaattga gtggttctgg
    25021 agatgcttct ttttatatta ataaggataa atatgatttg aaatcgttgg acagagaatt
    25081 atttatagat tctaaattag aagaggctta tcgaaaatta gatggtaatt tagaacatca
    25141 ggatcaggtc accttatttt tagattttcc atttttatat cctggaaaaa atgaaattaa
    25201 atggacgaaa aatattcatt catttgaaat aatgcctagg tggtggagaa aagtatgaaa
    25261 ccaagaatat atagtcctac tgaaacagat ttctcaacga atggcttagg aattttaaag
    25321 gattgtacaa gatgtggaat atatgaagta gctaatggaa aatatgaatt agagttggat
    25381 tatcctttag gaactagatt tgatgaatat tttgaaaatg actatcaaat aaaagcaaag
    25441 ccaaacgatc aagaagagta tcatatcttt tttattgatg ataaagatat agatactttt
    25501 ttaaatacag taactattta tgctcagagt cgtacaaatc gacttggaag acgggtagtc
    25561 actcttgtgg aagtggactc taaaactggt caagaagcga tatcaattat tgaaactaaa
    25621 atggataaaa aatctgacat acgactttat tctgatatta cggctgtttc tagcacaatc
    25681 tttgaagcga gaaatgtttt aaattgtatt gctggtgaac aaggatcatt gcttcaatat
    25741 tggggcggag aaattaaacg tgaaccattt aagctttctt tgttaaagcg aagaggtcgc
    25801 aataatgttg gaacgattcg gtatggaaaa gatatgtctg gtttgaaggt caaattagat
    25861 tggacaggta taaaaacaag aattattcca tatgctgatc ctcaaagtga agtaggtacg
    25921 actaatcgaa tttatggttc gccagtagat agtgcctata ttaataacta tcctgatgtc
    25981 tatacagaac atgttcagtt tacagaagaa caaggagtaa aagacattaa gagcttaaat
    26041 aaaatagcta aaaattactt taaaacgatc aatcctggct gtgataagcc taaagtttct
    26101 attacggttg aatttgataa gttgactgat agtgaagaag cgaaagaatt tgcgaagatt
    26161 agaaattatg gtctgtttga tacatttaaa atatatcata aaaaatataa tatttatctt
    26221 gaatcaaagg ttagtggact acaatacgat tctttatctg aaaaaacttt gaaattagaa
    26281 gcaggagaca ttcaagttgc tttttatcag caacaagctg taactattca ggataaatta
    26341 aaagattatg caacgaataa ttatatgagt gattttaatg attatgtttc ttcaatgatt
    26401 acaggtcaag gcagtgcagg aggatatgta gttttatggc caaaagaaaa accttccaac
    26461 atctttatta tggataatcc agatttagaa aaggcaagag aagtactaag aatgaataaa
    26521 aatgggattg ctttttctaa gaaaggatgg cgggggcctt ttaattcagc ttggacatta
    26581 gatagtatat ttaatgccaa ttttatacaa actggattaa tcaaagcaga tatctttcaa
    26641 aattctttta acaagactgg agatgtattg aaattagtta atggactact ccaaatttgg
    26701 aacaacaaaa agaaaataat ggagttaact aaaaaaggaa tggaattttg gaattctaag
    26761 ggttcaattg gaacgattgg aacaactgat tctgttggta atccttttcc tggggcttct
    26821 actccaaccc ctattgaaga taattcttta gttattcgta caaatggaga cggcaaatat
    26881 attttgattt ctcctaaagt aggaaaagga ttagttttat taggaaatgg taaagcaatt
    26941 tattttggag acttagatgt acaaggaaaa cttacagtta aaggaaaaga aataattcct
    27001 ggacaaggtg gtggtccatc gggaggtgga gaatctactg gtgggtatcc tagtgaatta
    27061 aaaacagatg cagaaaagag agcttggaga at
//
LOCUS       DADGKS010000032        26160 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.032, whole genome shotgun sequence.
ACCESSION   DADGKS010000032 DADGKS010000000
VERSION     DADGKS010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26160
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.032"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(62..1093)
                     /gene="queA"
                     /locus_tag="JXV47_001511"
     CDS             complement(62..1093)
                     /gene="queA"
                     /locus_tag="JXV47_001511"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HAX1487562.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            1286..2461
                     /locus_tag="JXV47_001512"
     CDS             1286..2461
                     /locus_tag="JXV47_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HAX1487563.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            2465..3106
                     /locus_tag="JXV47_001513"
     CDS             2465..3106
                     /locus_tag="JXV47_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1487564.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            3103..4020
                     /locus_tag="JXV47_001514"
     CDS             3103..4020
                     /locus_tag="JXV47_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HAX1487565.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            4017..4688
                     /locus_tag="JXV47_001515"
     CDS             4017..4688
                     /locus_tag="JXV47_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1487566.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(5229..5717)
                     /locus_tag="JXV47_001516"
     CDS             complement(5229..5717)
                     /locus_tag="JXV47_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HAX1487567.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(5918..6184)
                     /locus_tag="JXV47_001517"
     CDS             complement(5918..6184)
                     /locus_tag="JXV47_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAX1487568.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(6184..6447)
                     /locus_tag="JXV47_001518"
     CDS             complement(6184..6447)
                     /locus_tag="JXV47_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAX1487569.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            complement(6440..6712)
                     /locus_tag="JXV47_001519"
     CDS             complement(6440..6712)
                     /locus_tag="JXV47_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487570.1"
                     /translation="MYWCCCIDSQALDSTFAKDDTLLPITLRLATASRKGVRSERGQR
                     SSLKRGLFLYVKKRKSLLNLSALLYFFDVLNQVRYNYIRKRRRDNG"
     gene            6923..7108
                     /locus_tag="JXV47_001520"
     CDS             6923..7108
                     /locus_tag="JXV47_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAX1487571.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(7250..9073)
                     /locus_tag="JXV47_001521"
     CDS             complement(7250..9073)
                     /locus_tag="JXV47_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HAX1487572.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(9671..12376)
                     /locus_tag="JXV47_001522"
     CDS             complement(9671..12376)
                     /locus_tag="JXV47_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HAX1487573.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(12682..13629)
                     /locus_tag="JXV47_001523"
     CDS             complement(12682..13629)
                     /locus_tag="JXV47_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HAX1487574.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            13819..14088
                     /gene="rpsN"
                     /locus_tag="JXV47_001524"
     CDS             13819..14088
                     /gene="rpsN"
                     /locus_tag="JXV47_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAX1487575.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(14264..14626)
                     /locus_tag="JXV47_001525"
     CDS             complement(14264..14626)
                     /locus_tag="JXV47_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAX1487576.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(14637..15758)
                     /locus_tag="JXV47_001526"
     CDS             complement(14637..15758)
                     /locus_tag="JXV47_001526"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HAX1487577.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(15774..16124)
                     /locus_tag="JXV47_001527"
     CDS             complement(15774..16124)
                     /locus_tag="JXV47_001527"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HAX1487578.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(16254..17765)
                     /locus_tag="JXV47_001528"
     CDS             complement(16254..17765)
                     /locus_tag="JXV47_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAX1487579.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(18087..19439)
                     /locus_tag="JXV47_001529"
     CDS             complement(18087..19439)
                     /locus_tag="JXV47_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HAX1487580.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYLEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(19592..20668)
                     /locus_tag="JXV47_001530"
     CDS             complement(19592..20668)
                     /locus_tag="JXV47_001530"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HAX1487581.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            20864..22609
                     /locus_tag="JXV47_001531"
     CDS             20864..22609
                     /locus_tag="JXV47_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HAX1487582.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(22889..23326)
                     /locus_tag="JXV47_001532"
     CDS             complement(22889..23326)
                     /locus_tag="JXV47_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HAX1487583.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(23310..24683)
                     /locus_tag="JXV47_001533"
     CDS             complement(23310..24683)
                     /locus_tag="JXV47_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487584.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(25005..25493)
                     /locus_tag="JXV47_001534"
     CDS             complement(25005..25493)
                     /locus_tag="JXV47_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1487585.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(25515..26117)
                     /locus_tag="JXV47_001535"
     CDS             complement(25515..26117)
                     /locus_tag="JXV47_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAX1487586.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         7504 a         5561 c         4837 g         8258 t
ORIGIN      
        1 ctttgtcata aaatctttgt aaagcttttt tgttattcaa aactagcggc ttttcataac
       61 cttatttcac gaacatcgca tctccaaaac taaagaaacg atagcgctct tcaatcgcat
      121 gctggtaagc agataaagtc aattctcttc ctgcaaaggc actaactaac atgactaaag
      181 tcgattttgg caaatggaaa ttagttgaga aagcttctac cactttgaat tcatagccag
      241 gcgtaatgaa aatatcagtc catccgctgt ctgctttgat ttctccatta aatttcgttc
      301 caatcgtttc taatgttcga attgaagttg ttccgacagc cacgattttc ccgccatttt
      361 tacgtacttg gttcaatcgc tcagccgctt cttccgtcaa acggtagaat tcactatgca
      421 tatggtgttc ttcaatttta tctacgctga caggtcggaa tgtacctaac cctacatgta
      481 gtgtcagata gactaattca acaccctttg cttcgatctc atcaagtaat tctttcgtaa
      541 aatgcaatcc agctgttggc gctgcagcag aaccattttc tttcgcatag acagtttgat
      601 agcgatctgg gtcttccaga cgttctttga tatatggagg caatggcatt tctcccaatg
      661 attcaagaat ctctagaaaa attccttcat actcaaagtc aatgatccgt ccgccgtgtt
      721 ccaattcttc tttcactact gcttgcaatc tgccatcacc aaaagagatt cttgtcccaa
      781 ctttggcacg tttcgcaggt ttgatcaatg tctcccacgt atctccttgt gtattcgtta
      841 gaagaaggac ttctaaatgc gcaccagtat ctggtttttc tccatataaa cgagcaggca
      901 gaactcgtgt attattcata actagcgcat caccaggctg taactcttca atgatttcat
      961 ggaaatgttt atcttccatc tctccagttt tccgatccaa aacaagtaaa cgagaatgat
     1021 cgcggtcttt taatggtgtt tgtgcgatta attcttccgg caagtcaaaa tcaaaatctt
     1081 ctgttgttaa catatcgtca ctcactttct atcatgtgct tcatcattct atcatgtttt
     1141 tcgttctgtt ggcaaaatca gcactttttc acttctattt tttgttttcc taaataaaaa
     1201 aactacccta tttgtatttt ttcattgttt taggcatact agtaatagat agttcttcat
     1261 tgaaaataga aaaagaggtg gcaccatgat tgaatttcaa aatgtgtcaa aaatttataa
     1321 aggtggaaaa gtcgctgtag aggacgtcaa tctttcattt gaaaagggtg agttcatttg
     1381 ttttatcggt acgagcggaa gcggaaaaac gacgacgatg cggatgatca accgaatgac
     1441 tgatccaaca caagggaaaa ttttgattga tggaaaatcc atccaagaaa ttgatccagt
     1501 ggaattgcga cgtcagatcg gctatgttat ccaaagtatt ggattgatgc ctcacatgac
     1561 gatccgtgaa aatatcactc ttgtccaaaa attgttgaaa gtcagtcaag aagaacggaa
     1621 taaaacagct gaaaaaatga ttgatcttgt ggaattgccc cgtgagatgt tagatcgcta
     1681 cccacatgaa ttatctggtg gtcagcagca gcgtattgga gtcgttcgtg cccttgcagc
     1741 gaatcaagat atcatcttga tggacgagcc attcggtgcg cttgatccaa tcactcgtga
     1801 ttccttgcaa gaccttgtca aagatttaca agagcgtttg ggaaaaacga tcgtatttgt
     1861 aacccatgac atggatgaag cgattaaact agcaagccgt atcgccatca tgagtgaagg
     1921 ccgtgtgatc caatttgata caccagaaaa tattttacgt catcctgcaa acgatttcgt
     1981 agaagagttg attggagaag atcgcctact acaagccaag ccaaatgcga caagagtcgg
     2041 cgaagttatg ctaaatacag caatcacgat tacaccggaa aaatcattac aagaagcaat
     2101 caaactgatg agggaaaaac gtgtagatac gttgttagtt accgataatt cgaatgtatt
     2161 aaaaggattt atcgatgtag aaacgttgaa taaaaaacga ggaaaagtat ccagtgtcgg
     2221 cgacattttg aataaacatg ttttttacgt aaaagaatcc gcctatcttc gtgatacctt
     2281 gcaacgcatt ttaaaacgcg ggctgaaata cgtgccggtc gttgatgaac agaacaaagt
     2341 cgtaggtatc ctgactcgtg catcattagt ggatatcgtc tacgatgtga tttggggaga
     2401 agatcccgca actactgatg ttgcagagtc agctactcct gaagaatcta aggaggtctg
     2461 acctatgcag cagttttttc atcagcacgg ttcagaaatt ctctcaaaag gttttgaaca
     2521 tctttatatt tcaggacttg ctttgatcat tggtatcatc attgctgtac cgcttggtgt
     2581 cttactgaca cgttttccaa aagctgccac gattgtgatt ggcttaacca gtgccttgca
     2641 gacaatccct tctcttgctt tattggcatt gatgatcccg ctatttggcg taggtaaatt
     2701 acctgcgatt atcgcactct ttatttattc attattgccg attttacgta atacgtacat
     2761 tgggatgaaa aatgtcgatt ggaattatcg ggatgtggca aaaggcatgg ggatgactga
     2821 gttccaatcc attttttccg ttgaattgcc cattgctatg ccaacgatca tggctggtat
     2881 tcgtttagct gccgtttacg tgattgcatg ggctacactt gcctcttata tcggcgctgg
     2941 tggtttaggc gatttgattt ttagtggact gaataattac caaccagatc tcattttggc
     3001 aggtacgatc cctgtaacaa ttttagcact attggctgat tggcttctag gtctcttgga
     3061 acaccggctg acaccgatcg cacttagaga ggagaatgaa gaatgaaacg tatactaaaa
     3121 atgaccatgg ttcttttctc tcttcttata cttgcgagtt gttccttccc tggtcttgcc
     3181 agcaatacag atgaagacac catttcgatc acaggtggaa tcacttcaga agcacagatc
     3241 ttagcaagtc tagttgccgg aatggttgaa cattatacag ataaaaatac cgcaatcatc
     3301 aacaatctgg ctactacaac tatcaaccat caagcgatga tgaacggaga tgcttcaatt
     3361 tcagcggctc gctacacagg aacagattta acgactacat tgaaccttcc tcctgaaaaa
     3421 gatccgaaaa aagcgtttgc taccgtgaaa gatgaatttg agaaaagata cggtcaaacg
     3481 tggttcccgt cctatggttt tgaaaatacg tatgtctttc ttgttcgaaa agacaccgca
     3541 caaaaatacc atctatctaa agtcagcgat ctgaaaaatg tagcggatga attagtagct
     3601 ggtgtagata cttcttggat caatcgtaaa ggagacggtt atgacggctt ccaagaaact
     3661 tatggcttct ccttcaattc gatattacct atgcagattg gacttgttta tgacgcagtc
     3721 gaagcaggaa aaatggatat tgttcttggc tactctacgg atggacggat cgccagttat
     3781 gatctagtca tgttggaaga tgatcgtcaa ttcttcccac catatgatgc tgctccagtt
     3841 gtagacaaca agatattagc tgatacgcct catttaaaag aagccttaaa taagttaggt
     3901 cataccatca gtacggaaaa aatgcaggaa ttgaactacg aagcagataa taatctagtg
     3961 gaaccatcag tagtagcaca acgtttctta caagaaaacc actattttga agggaagtga
     4021 agcaattgga taaaatgaat gtctttcaac aatttttcta ttatttccag gaaaatggct
     4081 cctatatctt tgcacaattt atccgtcact tcctgatttc tatctatggt gtcctctttg
     4141 cagcagttgt cgggattccg gttgggatca tgatttctag gagacgtaaa ttagcaaact
     4201 gggtgattcg tttggcgaat atcatccaga cgatcccttc tctagccatg atctccattt
     4261 taatcattgg attaggcctg ggagtcaatg tcgtgattgt tactgtattt ttgtattccc
     4321 tcttaccgat catcaagaat acgtataccg ggatgatcca agtagacaaa aacatccttg
     4381 atgtcggcaa aggcatgggg atgactgcta gacaacgact attcatggta gagttaccac
     4441 tctctgtttc tgttatcatg gcaggcataa gaaacgcgtt agttgttgcc atcgggataa
     4501 ccgcgatcgg tgcattcgtc ggtgctggtg gtcttggaga tatcattatc cgaggaacca
     4561 atgcaacaga gggcacatcg attattttag caggtgcatt gccaactgca ttaatggcga
     4621 tcatcacgga ctggctttta ggtattttgg aaagacggct agatccagcc agccgtacat
     4681 cacgctgatg ttattgtaaa aaacaaaagc ttctgcgacc atttgttggt cgcaaaggct
     4741 tttttagttc tgtcattttt aaggcaataa tccactctga ttcttccctc cttatgggca
     4801 aagagttgct tttcttagct atttatccat tccgtatact ccaacttcat actgccaacg
     4861 ggttcatatc tgcatccacc gactaagttt ttttcttatc cgctaaggca ttttgccaat
     4921 ccattttccc atcactcgtc atggaattca taccacatga tctctaaata ctcgtctgct
     4981 tgttctttga attgggcatc aattcttaca tcctttggcg tggctttcat ttaagccttt
     5041 tccatcagtc ctcgattgtt cgatgccttc agctgcatca tcaaaactgg tgactgccgt
     5101 atcggtaact tcgatcatct tttatacaat caggaacttg ccatcctcat ccttggctaa
     5161 aaacatatct agccattcca gcttctcgcc atgggaggtt tgcggttcct aaaaccggta
     5221 cacgattctt atggactgca tccgtcgcaa ctagacttgg cgatacgatg atccttcacc
     5281 agaagagcac ccccgtaaac caattgatcg atatattgcc aataagaaaa gacattggcg
     5341 taaaagatat cgatccctcg tgatgcattg ccgttgatac tgctattcat ggccgaaagc
     5401 gccacgactt taacttcttc cgtttgagtg acattcatgt tcggcaatgt cgctttggat
     5461 acccgctctg ctaaaggaac gacactggta ttgtatttcg tatctgtatc ttttccaaaa
     5521 gaccatgcca acgaatcctc tgggaaccaa taagacgact ccggttgatt gtccattgct
     5581 tttttcaaca tacttttggc tgtttctcga taaacgacat ttccaattgt cttcgcctca
     5641 ctttggcgat aatcgatggt cgttgccact gccaacacta acaacgatgc tccaatttta
     5701 ctgattttcc ttgtcacact tcttcctcct tgttttacat aaacccgtca acattccatt
     5761 cctaaactca aacaatgacc cttcaaaggt ggagatatag gaacaaatta aagaaatcat
     5821 gcaataaatc caagaaggtt ggttttagaa caaaaaaaga gtctcctttt tggggagact
     5881 ctttgttaac tatctaaaaa ggttggctct tctcacttca ctcataatgt gtccaggcag
     5941 aataaatttc tacaacttta ttttcctcat caactttgta aaccactcga tgctgtctat
     6001 tcagcctgcg tgagtatctg ccttcatgtg taggtctcag cttttcaaaa gactgcgtgg
     6061 gcatatatgg atcttccttc aatgtctgaa tcacttcttc aaattgtttc tttaaattcg
     6121 tttgcttgat ttttcttaaa tccactttcg cagagttttt gattgcgact gtatagttac
     6181 tcatcaaaga gcttcccaat caatatcatc gatattcgta aagctactgt cgtctttttc
     6241 gcggtctcgt actttatcta aagtacctgt ttgctcaaga aaaagggttt cttgaatcgc
     6301 tctccagtct tccagcccaa tcaatacagc attgtttcca ctacgatcac taataatctc
     6361 gatttcagta tgattttcat ttacctcttt caataactga taaaaatttt tacgagcagt
     6421 gctaggattc atcgttgtat tagccattgt ctctcctcct ttttctgata taattatagc
     6481 gtacttgatt aagtacgtca aaaaaataca ataaagcact taaattcagc aaacttttcc
     6541 tcttttttac atagagaaaa agaccccttt ttagggagga tctttgtcca cgctcacttc
     6601 ttactccttt acgactagcg gtagccaaac gtaaagtaat tggtaacaac gtatcatctt
     6661 tagcaaaggt cgaatccaaa gcctgtgagt ctatgcaaca acaccaatac acgaaggttc
     6721 ctcgttgcag tgtgacttga ttgatatctt gaataacctg aggatacgca cgaaagattt
     6781 gtaacggtta ttcaaaactg attttggccg tcaagtcttc tactgcctca aaaatgattg
     6841 cctctttcgt ctcctgtcat tcatgttcac tatcgatttg atacttgctt agaccgttgg
     6901 gtttgtgaat caccaattaa aaatggcact gagttatggt aacaaaaaat ggtcacttga
     6961 cgaggctgag attcctactt atgaagacac atggcactta agagtcgagg taaaggaaga
     7021 agctgaaaat ataggaggct gtacattatt tggcaaagga ttcggaaatt atgatcaaga
     7081 catcaaaatc aaaatgtttt acagctaaat aggaagaata ataacatttc atacgctgtt
     7141 cccatcttta atggcttata gagggcacct ttagctgaga ataagacaaa acagaccctc
     7201 tagcttcaat taagagctag agggtctgtt tttgatttta aaacttggtt tatttcttca
     7261 aatggtagct ataggtgctg acaacgatat tttcacgcca agacaatcgc aatcttaacc
     7321 gcaaacttgt ttggttatgg agaatattct gccagcgtct gtttggtaca aattgaggaa
     7381 tcaacacagt agttgtatag ttttgtttcg ctgcattttt acttacgata tctacataac
     7441 ggataattgg attttcaatc gagcgataag aagagtggac gattgaaaaa cggacatctg
     7501 ggaaatgctt tttaaattct gcttcgattt ctttttcttt ttcgacatct tcgtctagcg
     7561 aaacatgcat cgcaacgaca taatcaccga tcgaacgtgc gtaattcaac gcaccgatat
     7621 ttacccgtgt cacattcccg actaatacaa gaacggtatt cccgtcataa tcatgtagtt
     7681 ttgcatcatt ttctaaacga agctgttctg ctactttttt ataatgatca tggatcttat
     7741 aaaaaatgaa cataacgatt ggcataatga tgaagaaagg ccaaatgtcc cctaaccgat
     7801 agacaaacaa aatcgcaatg attgcatatg agatgaacgc acccgtaata ttggcaatcg
     7861 atttgcttaa ccatcttttt ccttcttttt tccatttgac gaccatccct gtttgagata
     7921 aagcaaatgg aatgaacacg ccgatagagt ataacggaat caagcgttct gttgagccat
     7981 ggaaaataaa cagcaatacg atcgaaccta gcgctagtgt gataatccca ttggaatagc
     8041 ctagtcgatc cccacgatct tgatacatgt gaggcatgaa tttatctttt gccagattgt
     8101 atgcaagaac tggaaaagca gaaaaaccgg tgttagcagc aactgctaaa atcagcgctg
     8161 tagcaaattg aaggacgtaa tacaaaatac catgtccaaa gacagcttta ccaatttgag
     8221 acaaaacagt gacttctttt tcaggaacga tcccatacca atagttgata aatgtgatcc
     8281 ccacgaagaa gaaacctaag atcaatgcca tcatcgtcaa tgtagcagcg gcattttttg
     8341 ctcttggctt cttaaagaat ggtacagcat tactaatcgc ctccacccca gttaaagagg
     8401 aagaaccaga agaaaatgct cgtaaaatca aagcgataga aacacccggc acagccgctc
     8461 ctggaagtgc agtagcttgc aatggcacag cacctgtcac gatattatat aaaccaacaa
     8521 cgatcagtaa cgagatcaca aggataaatg tgtacaccgg aaataatagg aacgatgcag
     8581 attccctcag cccacgaaga ttcagcatca tcagtagcaa aacgattgtc acagaaatag
     8641 cgacttgatg accgtagagt gctggcaccg ctgatgtgat cgcttcagca cctgctgaga
     8701 cagatactgc tactgtcaac atgtagtcga tcaataaaga gccaccggaa atcaagccag
     8761 cattctttcc aagattctca ctgctgacga catatgctcc cccgccatga ggataagcat
     8821 ggatgatttg acgatatgat agcgttaatg aaatcaataa aataataaca aaagcggcaa
     8881 tgggtagcga ataccagatg gctgcagcag acaaagcgac taaaacgaca acgatttgtt
     8941 ccgtaccata tgcaatagat gataacgcat cagacgacaa taatgccaaa gcagcaaatc
     9001 gggttaattt gtgctcatca ttttcagcag attttaaagg cttacctact aacaaccttt
     9061 ttaagtaatc caatttctaa actcctttac acacaatttt acttcaagtt ttatagtcga
     9121 aaatttatag taaacaagat gttatagtac gctcactgac cttaaaagtc aataaacttt
     9181 aagaaaataa ttggaaaaaa acagaaaaat atcaagcgct ttttcaaacg ctttaataca
     9241 gcaaaaatct aacatttttt tatgggcttt ttctttgaat tctataataa aaggatagaa
     9301 cttgacttag aaaatcaagt tctatccttt ttgatatctt aacttttgga agagagatgt
     9361 aaggctgctt tctacccatc attcttacta ctcgaagcat agcgcagttg tcacaacctc
     9421 ttgataaacg gtgtttaaaa gcttgcatct gcggtaataa gcccaaccaa attaaaaaca
     9481 taagaagctg tttttatttg gtcgttctta ttacttgatg cagagcagct tttttacaac
     9541 ctcttggtac acggtgttca atcagctgac cctcggtatt agctcaaaaa aacggcaaaa
     9601 tatgaggaac tatttttcca tttttttctc taatactcag gtcaaaacac tgatttcaca
     9661 acctcttttt ttaatgaaaa atatggctct catgcgccgc ttctttgaat ttcgtcattt
     9721 tttcttcgat gaacggatag attgccgttc ctacgattcc aaagacaaca aacaaaccga
     9781 tcatgatcca gattgctttc gtagcatttg gccaataaat tcctcctgca gattcccgta
     9841 acaagtttac cgcatgagta aatggcaaga acggattgat catttggaag aatttccctg
     9901 agacttggat cggatagttc ccgcctccgc cagagatcga cagtactaag atgataatag
     9961 cgatcccttt accgacatta tcgaataatg cagccaagac atagacgatc atcatgaacg
    10021 ctaaggcgat caagacagca aatgacacgc tgtagaccgg attttggaca tctactccta
    10081 gtaagaaaat attccctaat gtaacgatca agctttgcgc aatcgccatt gtcaaaaatg
    10141 tcagcatacg agcaacgaat tgttctcgtt tcgtaaaatt gtttcggtct ttctttccta
    10201 aatagtattc tgtcgtagca acacttgaaa gaagaacagc gccgacccac agacatagtg
    10261 cagtataaaa cggggtgcta gctgaaccgt tatttgcgat tggataaagc gcattggttt
    10321 gtagctcaac aggttgtgta aagaagtcac tttcttttgt tgcgtctagt ttcaataatt
    10381 tgatgacttc gcctagatcg acttcttgtt cgccttttcg gatcgcgtct gctgcttttt
    10441 ggataccagc tttgatattt ggccagtcat tgttgatcaa gtccgcagca gcgttcacag
    10501 ctgtttcgac ttctggcatt ttttcattta ctgttgtcaa tgtaccggtg atttcatttt
    10561 ttagtgctgg ccaatcattt tggataaaat cagcggccaa tcctaatttt tgctgaatga
    10621 tcggtaattc attgttgtat aggtctgccc cttcattgat gccattgacg atggtatcca
    10681 tatttccatt cagcattgta ttggcatcat ggatttcttg tccaattgca ggcatttctt
    10741 tttgatattt ttctaaaatt gccactgcat tcgttacagt tgctttcgtt gagctgagaa
    10801 gcgaatcaaa gtcgatctgg tccgctttgc tcagtgcgcc ttgtgcagtc ccaatcgtat
    10861 cgatgacttg gtctagtaga gaagtgacag tggaactgat ttgacctgta ttgataccag
    10921 caatgatgcc attgatatta ttaacaacgg catcaatttg atctagcaat tcatcaatag
    10981 ccttcgtgtc ttcattttga acagctgtgt tcaaagcaga taggcggttt tgcagattgc
    11041 ttagcaaggg ttttaattga tttagctgat caataattgg ctgtaatttc gtatttccag
    11101 cacttgtttg caatttagtc aggaactcga ccagtttatc gattgcattt tgttgttgag
    11161 atattccgtc aataaagccg ttcaatacat tgctgatgtt tttcttttca tcatcagtca
    11221 gcttaccatc ttcaatagct gttcttacag tatctattaa cgaacctgtc gttgttgcca
    11281 cttgtccaat tgacttcaat gtaacatcta cactgtttgt gatgcttggt atcgcatctt
    11341 tcagctgaga ggcacctgat tttgtttggt ttgctagatc acttgcctga ttttctaaat
    11401 ttttcacatc tggcaagata tcttgtactt gttggatgat cgtcaagcct tgttttgctt
    11461 catcgattcc ttggttcatt gtctcttgga tcgaagcaaa atcgccgtcg atctctgcta
    11521 gttgcttacc ggcattttgg atctctggga ttttttcttg caaatcaagg atgatttttg
    11581 cttgatcttt caactcaggc attttgtcat tcaatgcaac gactttttca cccatctcat
    11641 ctactttagg gatgtaatcc acgaattcat ttgctttatt cagtttttcc ttgatttcag
    11701 gtagttgact ttgtaattcg aggacttgtt ttgtgtagcc gtcgatcgtg tccaaatttt
    11761 catctgttga taaaatcata tctttaactt tattgatact tactaggttc gtatcgatgt
    11821 cgtaacctat ctcattgaat actttcaata aagtcgaact ggctgttttg ataaattcat
    11881 ttgtgatttg cgattggatc gaacttgctc ctttatcggt gattttcggt gcaatcgcat
    11941 tgattttttc atttaccgta tattcgattt ttggtttctt gatatcacca ctagtaaaac
    12001 tcagcagatc ttctgagaaa tcctttggca agtaaatacc tgcgtaatac tttccggaac
    12061 ggactccgtc ttctaattgt tcttttgaat caacgaattg ccatcctaat tgtttatttt
    12121 tatgaagcga ttcgatgact tgctccccaa tggccacttc tttaccttga aactctgctg
    12181 gcttgtctgc actgtaaaca gcaattggca gctctccagt atttccatat ggatcccata
    12241 atgctttgat gttaaaccac gcatatagcg aagggatgat catgatcgcg atgatcagaa
    12301 gtgttgcaat cgggtttttg aaaatccgtt tccagtcaag caaatataat cgaagcgtat
    12361 ttttgattga ctgcatagtt ctcccccttc ttcttttttc agctgaatta ctttaccatg
    12421 tatttcatac ttttttcaat cggctttttt caaaaaagtc gaatttttgg acatatcacg
    12481 gcaattgtct cattgtaatc tcttacatat tgagaaataa ttaaggatta cagcctttac
    12541 tttatcatga aataaaaggg aaagataatt ttatgccaaa gtttttatct attatacgta
    12601 tacgcaaaaa agctaaaaca ttttttgtct ttgcccctac aaaaatgttt cagctttttt
    12661 cgttttttat tcctgtattt cttatttttc gaatgacagg atgattttcc cagcaggagg
    12721 atgtccttca actagctgat gtgcttggat gacatgctta agtgaagcag acagattcat
    12781 tgaaataaaa acatgaaagg ctcctttttg gtaggctttg attatgccag caaaggcttc
    12841 tgcatctaga tattcctttc ttggaacaaa cgattcataa aagccttcct ttttttgccg
    12901 caaatctaga tctgggaggt catttaatgc aacatacctg ccgcctggtt tcatgatctg
    12961 gatgccggtt tctcctttga tacttccttt cgtcgcatcg attacaaggt ctgcctgatc
    13021 agcaaattgc agacctggat ttgttttatc ataagcagca aatgctgaag ctcctaattt
    13081 ttttaccttt tcctcatttt tactggatgc actggttaag attcggattc ccttttcatg
    13141 gagaagctgg atcagacttg acccgaccgc acctgatgct cctagtatca ttacagtatc
    13201 tgtcggctgg atttccgtca aatggttgat tagattataa gccgtaattc ctggcgtgac
    13261 cattccggct gcttcttccc aactcatttt atctggaatt tttgctactt ttgctgatgg
    13321 caacacgact tcttctccgt aagtcccgcc gactgcatgg acagctactc gatcacctac
    13381 atgaacagtt gtgacatctg aaccaatctc tgtcacaata ccagcgccat cattacctgg
    13441 tacataaggg aatttcaatg ttcgtatctc tttcatttct cctaaacgca aggcaacatc
    13501 ataaggattc acactgaatg cttttatttc tacacgaaca tgtccagaac cgacttctct
    13561 gggatgagca tcgatttctt caaaaacatc ttgtgcttct ccgtaaccgt taattgcaaa
    13621 tcttcgcatg gtcaccatct ccctttttct ttaagtttac gtttatgcct ttattttgac
    13681 aaaaaaaatg tcttttcgtt ttggcgcatg attcaaaaca aaatagttgt cttttttcgc
    13741 gtaacgtgtt aaattattta tctaaaagcg taaagattac gatttacgct aataaaaaat
    13801 aattggagga atttgttgat ggctaaaaaa tcaaagattg ccaaagcaaa aaaacagcaa
    13861 gaaacgattg aacgctatgc tgctttacgc caggaattaa aagcgcaaaa agattacgaa
    13921 ggcttgcgta aacttccttt agatgctcgt ccagaacgat tgaaaaatcg tgatttaatc
    13981 gatggacgcc ctcgcggata catgcgtaaa ttcgggatgt cccgtataaa attccgtgaa
    14041 ttagcacata aaggtttgat tccaggagta aaaaaagcca gctggtaatc caagtctggc
    14101 tgtaatgtaa aggaggaggg cgcatggacc actccttgga tcatcaaaaa agatacgttc
    14161 gcttcttcta gcagaaatgc tggtactaga agcagacgta tcttttttta cgcacagctg
    14221 gtcctttttt atatgtaaag gctgcatggt tacttcgcta tatttattta gtaacaggag
    14281 tcagtgcttc gatacccaca ctaattttca atgctcggtc aacttctgcc ataatgggtc
    14341 gatccaaatg gcagaccttt tctttcaatc ttgatttatc gatcgttctg atctgctcca
    14401 acaggataac ggagtctctt tctattcctg ttccagtagc tttgatccca atgtgagtcg
    14461 gaagcttagg tttagccatt tttgccgtta tggccgcaac aatgatcgtc gggctaaaat
    14521 ggttacctag attattttga ataaccaaaa ctgggcgtgt tccgccttgc tccgatccca
    14581 cgactggaga aagatcagca aaataaatat ctcctctttt taccatagga tcctccttat
    14641 tcttgatatt ctcttggtat ccgctgtcct aatccgcaag ccacttcata gtggatcgta
    14701 cctaattgat ctgctatatc ctgcatagtg atttctttgt ctgcattttt gccgataagc
    14761 gtcacttttg ttccgacagg aaattcttga ggcaatcgga tcatcagttg atccatacat
    14821 acacgcccaa tcgtttcaca gtagttccct tctaccaata gagaaaaacc ctgcatcttt
    14881 cgtggccagc catctgcata accgatcggt atcgttccga tccactctgc ttcaggagtg
    14941 atatatgttt ctccatagcc gattccttca cctgctggga gttttttgac ttgaatcaat
    15001 tcagaaacca gctcaagtgc tggctgcaat ggataaactt ccggtagtgc gtgcccagag
    15061 ggattaagtc cgtacattgc tactccataa cgaatcatat tgccgattgt ttcatcatgc
    15121 cataaagccg ttgcactatt gctgacatgt acatatcgag gaagttcggg aagttttttc
    15181 agcacttcta taaagcgttc tttttgcaga ttccaatatg tatcatctgc ctgatctgct
    15241 gtagaaaaat gggtaaataa accttcccat tctaatacac gactttcttt gatgaatgca
    15301 gctgcctctt ttacttcttc aggtgtacaa aatccgatac gacccatccc agtgtctgct
    15361 tttagatgaa tcgaaagagg cgtctctagc ttacttttct ctaaaacagc agctgctgct
    15421 tgcaaccatt cccgtgtacc tgcagttact gataaatcat gagcaacagc tacagtcagt
    15481 gcgtcgtaag gaaccatatt caagataagg atgggctgag taaatccagc ttctctcaac
    15541 tcgactcctt catctaaatt tgaaacacaa aagcccgaag ctccacctgc aactgctgcc
    15601 tcagctgttt caatagctcc atgaccgtat ccgttcgctt ttactactgc aaacaattct
    15661 tttccttgcg gaagtcttgc aacttcattt gctacatttt cagttatagc ttttttatgt
    15721 atcactgctt tcgttgggcg gtgccaagcg acaaccatcg tttttccttc tttctagtct
    15781 tccaaaataa tttgtgcaaa agctgtttca tttgtatgag taatactgac ccatacattg
    15841 ccttcatgag gtgaacgcgt cacaacaggc tgaccatttt cattttttaa aatctcgaca
    15901 tcttgaaagg taacttttcc gatcccagtt ccccaagctt tagagaaagc ctctttgcaa
    15961 gcgtaacgcc cgcctaaaaa ttctacttgg cgatgaaaag gcaaggactg gaatagtttc
    16021 atttcatcag aggtcaagat tcgtgcaatg aattttggtt tttcttcgat cagccgagtg
    16081 atcctaggaa gttcgactgc atcgatccca attcctttta tcatatgctt ttctcttttc
    16141 aataaattta gaacactctc attctaccaa attataacca ttttgccaca aataagtcca
    16201 caaataacaa aaatgaaagt ttctcttaaa aaagagaaac tttcatttta tgtttaatcg
    16261 ttatttgaac ggattacaaa tccgcgtttt ttatcattgt gacgtttacc gccatctttt
    16321 tggctgttat tatttttgct ataaccgcct tttgatttgt ttccacgata attaccgccg
    16381 tcacgacgat tacggttgtt tccgccacca cgtttgccat ttttattgta tccttttttc
    16441 tgcattggca atgggcgttc tggtgtgatc ttcactggca ctgcatcagc tggatctttt
    16501 gctgtcgttt ttagcaaaag tgcaactaaa tcttgtgcag aatattcttc taataattta
    16561 tctgctgttt gcaggtattt atctagacca ttttctgcaa gttttgtttc gatttgttca
    16621 actgcagcac ctaattgacc tttgaatgct tctttttcgg ttggtggacg taaagtcgtc
    16681 atccgttttt tcgtcaagtt ttcaatcaca tgcaagtagt ccatttcatt tggtgtaacg
    16741 aaagtcacag acataccgcc ttttccggca cggcctgtac gtccgatacg gtgaacgtag
    16801 ctttctggat cttgagggat atcatagttg tacacatgag tgacacctga aatatctaat
    16861 ccacgtgcag caacgtctgt cgctacaagg atatctaaat gaccgctctt aaatgaacgc
    16921 aatacgctca ttcgtttttg ttgagacaaa tcgccatgga ttccttctgc acggtaaccg
    16981 cgtgcttcta atccgcgtgc caattcgtct acacggcgtt ttgtacgtcc gaagacgatt
    17041 gttaattcag gtgtttgaac atcaaacaag cgagtcatga tatcgaattt ttcgtattct
    17101 tttgcgcgga catagtattg atcgatcaag tcagctgtca tttctttcgc tttgatcttc
    17161 acatgatgtg gatttttcat gaatttaacg ccaatattct tgatagctgg cggcatcgtt
    17221 gctgagaaaa gtaatgtttg tctttgatca ggaacttgtg aaatgatttt ttcgatatct
    17281 tccaagaagc ccatattcaa catttcatct gcttcatcca aaactaatgt ttgaacggtt
    17341 ccaagtttca atgtgtggcg gttaatgtgg tcaagcatac gtcctggtgt acccacaacg
    17401 atatgtggac gatctttcaa gccacggatc tgacggccaa tatctgctcc gccgtaaacg
    17461 gcttgtacac gtactttttt gtcgcgccct aaacgatata attcttcttg tgtttggata
    17521 gctaattcac gtgttggtgc gataactaaa ccttgtaatt cgtgacgatc tggatcgatt
    17581 ttttctaaca ttggtaatcc aaatgcagct gttttccctg tacctgtctg tgcttgtcca
    17641 ataacgtctt ttccagctaa tgctagtgga atcgtttctg cttggatagg cgttgcttct
    17701 tcaaaaccag cgcgttcgac tgatttcaac aattctggtg ataattctag ttctttaaat
    17761 ttcaaatgaa tcctcctata tggttgttaa ctgaggatgt agcttttttg ctaccccgtc
    17821 gatttgttcg gtcaaagtgt attgtttctt tttgacagtg gccacgcacg tttttatcca
    17881 ttcttagccc ctgtggcacc accgaaaaat cactttgcga agtttaggca ttagaaaagc
    17941 caaacgggtc gcgttcagct ttatcattat tatgacatct ggcttcaaca agttgtttct
    18001 atggcaaaac cagtccaatt tctcttcatc tttcggcaat aggttattct aacatagttt
    18061 ttcgttttct gcaagtttac agatttttat ttcatttgct gaagttgttc taccacttca
    18121 aataagccca tgctgttgct gccttttagc ataatactat ctgttgcttc aagattttgt
    18181 ttgatagcat caatcaattt attcttttct ttttccaaat agaacacagg tagttggggg
    18241 tatttttggt tcaattcttc ttttagtgca tgcatttgtt ccccataaag gaaaatcatg
    18301 gcgaatttct caggatcgat atgttcactc atttgcgcat gcatatttaa agactctttc
    18361 cctaattcca gcatatctgc taacacagcg attctgcgtc cttttgttgg cagattttta
    18421 aaagtatcta ataccagtcc catggctgtt ggatttgcat tgtagacatc gctcaaaata
    18481 gctgcaccat ttcctgccgt tagccattcg gttctgtttt gagtgataga aacatgggcg
    18541 agcccttggc gtatctcagg tatggacagt ccaaagaagc gcccgatcgt atacgcaatc
    18601 aaagcattcg ttacattata acttccaggc agcgggatcg taaatgtttc tccttctact
    18661 acaaaatcgg tttgtgcttt tccttttgct gtcacttccg catgaacatc gccatttcca
    18721 ataccgaatg ttgtgactgt ttgtactaat gttgccgtta aaggtgtcag caacggttca
    18781 tctgcgggca caacgagtaa tccgtctgat acaagtccgt cagtgatttc cattttggct
    18841 ttagcgattc cttctcgcga cccaagattt tctatgtgtg cttcaccgat cattgtgatt
    18901 gctgcagctt ttggttgagc cataagtgaa agttccgtga tttcattggc gtgatccatg
    18961 cccatttcca aaacgatctt ttctgtatct tggggcatgt gcaaaatcgt gtaaggaaga
    19021 ccaatattat tgttgtaatt tccttgcgtc ttatatgttt tgtatttttc agacaagaca
    19081 gacgcggtta gatctttcgt ggtggtttta ccattgcttc ctgtaattgc aacgacttct
    19141 gcgcctactt tttccaagta ataggttgcc aattgctgca tggctttcaa aggatctgct
    19201 acaggaataa ctggaaaatt ttttggagct tgttcaacag gcaagctcca aaatgaagca
    19261 gatgctccgt ttgtgatcgc ttgctggata aattcatgtc catctcgcgt accagcaaga
    19321 ggaacgaata aacttccttc ggttatcttc cggctgtcaa attcgacatt ggtaatcttt
    19381 gtcagtgcag agcattcgct gcccacggct tgtgcaattt cttgtattgt tagattcatt
    19441 gagatctctc ctaaaaaagg ttgtgaaaaa agcgtttggc ctaaacggcg ggttcgcatg
    19501 actctcactt ccaagtaaat ttctctattc gtatttagaa gctagaatga acgcggttac
    19561 gcaatcactc cagcctcttc tttatttctc tttattcatt tttttcaaaa aaagattgac
    19621 gctgatggta tcgattcatt cctaactgga tcagttcttc aatcaaatca ccgtatttca
    19681 agcccatatt ttcccataag agtgggtaca tactgaactc cgtaaatcct ggcatagagt
    19741 ttaattcatt caggaataat tcatttttat ttgtcaaaaa gaaatcgcac cggctcaatc
    19801 cgcttccacc taacatcgtg taagctaact tcgcgtactc ttgcgctttt tgataaactt
    19861 cttctggcac ttcggctgga atctgcattt cgattttatt attgatatat tttgcttcat
    19921 aatcatagaa tgctacgtct tttacgactt caccaggcaa agtcgtccga acgtcttcat
    19981 ttcctaatac agcaacttcg atttcgcgcg cttcaattcc ttgttcaacg attgctcgag
    20041 aatcatactg ataggctgtt gctaaagcat tttgcagctc ttctcggttt tctgcttttg
    20101 taatgccgac actagaaccc atattcgccg gtttgacaaa catcggataa agcaaagaac
    20161 cttcacattg atcaaatact tttttaggat tttctttcca ttgattctta agtactggta
    20221 cataaggaac ttgcggcaca ccagcagctt gtaaaatata cttggtcatg attttatcca
    20281 tggcacatgc actggtcaat acgcctgcgc cgacataagg catattcaat gtctctaaga
    20341 agccttggat cgttccatct tccccgtttg gcccatgtaa aactggaaaa acgatggctc
    20401 cttcttcttt gatttcgccc ggattgatca cttttcctgt aaagccttcc tctgtctgtc
    20461 cacttgggtc ccatgaaaga tgcaagacat ctttgctggc aggtttttct gttagtaatg
    20521 gacctttgac ccattgtcct tcttttgtaa taaatacgag ttgaacttgg taataattat
    20581 aataaatggc atttaaaact gaaaatgcgg aaagaatgga cacttcatgc tctgcgctgc
    20641 gtccgccata tagtaaagta atcttcaaaa gattgtcctc ctgtattcta aatcgttcag
    20701 tgatttactc tcatatttta gcacaaaaca aaaataaacg aataacttat ttataaaaaa
    20761 acgagccagc ttctaaaaga acgagcgtca tttatttttt gtcagctaga ttatttgtcc
    20821 cgttttttat aaaaagttat gataaagaaa aggagggatg atgatggcgc aaacaaatcc
    20881 acgcagccgc ttggcagaaa tcattcgagt gttcatcaat tacaatgtag tgccaaactt
    20941 tgtacagcaa aaaaatcccg aacaggtaaa aaaagccttt gaagaactag gccccacctt
    21001 catcaagata ggacagatgc tttctgttcg agaagatttg ctttcttctg ccttcactca
    21061 aacattcaaa acattacaag atagtgtacc tagcgacaca ttttcaacgg tcaaaaagac
    21121 gatcgaaaca gaactttctc tttcattatc agatatattc gatgattttt caaaatcgcc
    21181 ttttgcctct gcttctatgg ggcaggctca tcgtgccaag ctgaagaacg gtgacgcggt
    21241 agtcgttaag atccaacacc ctaacatcgc cgaagagatc cgacttgatc ttcaactatt
    21301 tgaacgagcg atccctttga tcaaatacat tcctgaaact agcgtagttg atctaaaagg
    21361 ggtactccaa gaagtaaaac gttccttgat caatgaaatg gacttcttaa aagaaagtca
    21421 aaatggcgaa caattctatc aaaagaacaa tggctggaaa gagatccgca gccccaagat
    21481 ttatgacgct ttttgttcga aaaaagtgat cgtgatggaa gaaatgtctg gtaaaaactt
    21541 gaatcattta atgaacgccg aaaacaaaac tgaaactttt atcactggaa ttcaaaacaa
    21601 gcagctgaaa caagaagttg caaagctttt agttgagaac tttatgaaac aggtgtttga
    21661 tgatggtttt ttccatgctg atcctcatcc agggaatctg ctattccatg tactaacaaa
    21721 agaagaacag acacaagcta gccgaaaaac tgaaacagtc catgaaaaag agttcggttc
    21781 ctttgctttt cgagcctcca cttctgcaga agaccctgtt gcgccatata ccatcaacta
    21841 catcgatttt ggtatgatgg ggcatctttc tgcaggactt aggcaaaaac tcacacaagc
    21901 cgttttagcg ctgtatacga aagatgctta tcgaatcgaa aaagcggtcc ttcgactttg
    21961 tcagcaagaa ggctcgtttg atgaaagtcg gttccaccaa gaactgacaa gttttcttga
    22021 acagtattat gattctccta ttgatgaaat caacttgcaa gaagtattca cacatgtcgt
    22081 gacgatttgt catcaaaata atctgcagtt cgatcgtgat atcacgcttt tgctgaaagc
    22141 atttgggaca ttagaagggg tgatccgcgt cctcgatcct gaagtttccc tcatggaagt
    22201 cgcttcgcct tttgctcaac attattttct cactcatctg gatgtagaag atacattgaa
    22261 acaaagcgga ttagacttat tggaagggat gaaggctgcg cctaagatcc ctcaacagct
    22321 ccaccatcta ttagaaatgt ggacttcggg acaaggaaaa gtcaatttgg aattgaaaaa
    22381 gcaagacaaa ttattgagca ggatcgaaag tatgatcaat cggcttgttt tcggtatgat
    22441 tttagctgca ttgatcgtag ggtcctccct gcttgtccaa gcagcacctg tagaaaacgc
    22501 agaggtcgtt tccttattag ggatatttac gtatgctatt gccgcattcg tcattatttt
    22561 tttggcaatc gatgcattga tccaaatgta taagaagagg aaaaagtaga aaaaggttgt
    22621 gacagaaaga atcagcttca agaaataaga aggggtttta cataaattgt ttctcaaatt
    22681 tttgtgaaaa ttcggcttat ttttcgaaga ggctacttct gaaacaccga gaataaaaaa
    22741 tgtgaaaaag ctgttctgca cccagtaata agaacaatca aaaagggaac atggaacaca
    22801 tttatcctgt ttccctgttc cctttttgat gtattcgagc ataaataaaa taccttcgtt
    22861 acctactatc ttctgtactt ggtaaacctt agtcaattgc cttttttaac gcttgacgaa
    22921 aagacatatg atctttctcc gtaaagggtt ttggaccctt tgtccttatg ccagcttttc
    22981 ttaactttcc actatgataa cgttgttcta gaagcgtgcc gatattcgct tcgtcaaatt
    23041 cttttccaga gtgatggaac actcgcacac ccttcggcaa tacaagtgaa gctaaaccat
    23101 aatcttgcgt gatcaaaaag tcattcttct taaccatacc gacgatttta taatccgcac
    23161 tatcagctcc gcggtctacg tagacgattt ggacatgatt agcgtattct ttggtcgtat
    23221 aatggtccac actggtcacg ataaccacgt caagaccata ggattctcct aattttatga
    23281 catcttcttt tactggagaa ccatctccat caatgaatag cctcattctt tttcgccttc
    23341 ttccataaat gataaacagt tactaatccg ctcagtaaaa gaccaacatt gatccatttt
    23401 gccaagataa gcagttgtac actttctatc ggcactgatt catggttcag cgtgatcaat
    23461 aatagatgga ttggctctcc catttctttt gctaaaacaa acaaaagcgt catcaataaa
    23521 aactggtgga tcacactccc tttattttga gtagtatact tgacaacgat ccggcgatcc
    23581 attggaatag ctgtatcagt ttgataatat tccttattta gccagctgcc tgttactacg
    23641 tgccagaaac taagcagaaa gacacctatc gcaaaaccat ttggaatcaa gaggaccaat
    23701 aaagaagaac tcagtccaag caattgcata gccaatggag accatgttaa acgtttcaaa
    23761 atccatggtc cgactatttt tgctgcaatc aagcctgctg cataaggcaa atacataaaa
    23821 atcgaaagtt tttctaatcc gtacagtatg ccaacataaa aactgctaaa taaaaaaagg
    23881 aaattcccta gcattccatt tagaaaagta aacagattta gccagcttgg caacttccat
    23941 tccttcttct ggtgtcctaa aacaaacacg aacaagatga acagcagcaa gaaaccataa
    24001 atagcaagat caaaaagcct ttcatcgaat aacaatcggg catttctcaa aagaaacaat
    24061 aagccaaaga atatcaaaaa taaaacaagc tctcgcgtag ctaccagatt tcttttgatg
    24121 tctttgaaat ccagttcgta acgcggataa tgactaaccg tatggtaggc catgacgtaa
    24181 aaaagtgtat aaatagtaaa gcttgctgca atctgagtcg gtgcaggcaa ctcaatcgct
    24241 tgatacagga gaaatagcca gatagctgca aataagtact ttttcccatc catattgata
    24301 aaaccttgcg tcttttcgtg aaaattgacc gtggtattag caggtacaag ccatgctgca
    24361 ctcagcccta gcaaaacact tgaaaaataa aataaaggaa aataaaatac gcctaatatt
    24421 ccaagcaatg aaccagcacc accaatcagc agagcgatca tcagcaacgt gtaactatct
    24481 agaccaaatc gtagactgtt gactaaaaat agtccagtca tccgaaaggc ataaaacagc
    24541 gtaaatggca aaatcgtcag ccaattatgc gagtctgtta gtcccaaaaa taaaagataa
    24601 ggaataaaaa taaccgtgtt acttaagata aagggcgttg tttgtgtaaa attacgccca
    24661 aatcgtttga gtttttcgaa catgacaatg gctccttaaa cagtcttata actaatctgc
    24721 tcttcgattt tagcattaaa ggggaaataa accaatttta cagaatatat tcttgtaaaa
    24781 aaaaatacag aaagaagcat aagcttcttt ctgcattttt acggtacttg attactcaag
    24841 cagacaagcc cttctccaca aaagtcttgc ccgacacccc tgcatccggc aggtgataaa
    24901 gatagaaatc aattatcctg tgcctccaaa atcaattagg agctctgtaa accagagtcc
    24961 ttctcgaccc gtcgcataaa tttactttaa cacagttcct atgtttatgc gagagctttt
    25021 ttcattttat aatcgaccat ttgaaatcct tgaccgatat ctgaaataag ttcttctgta
    25081 atctcaaatc cttcatgctt ataaacctcg attgcttgat gattcccctg attcactcgc
    25141 aaaaagatct ctctttcctt tgtttgcgca gcaagttctt cataccagcg aaaaactgaa
    25201 gaagtcaatc cttgaccacg tactttattt agcaaatata atttacttaa ataaattttt
    25261 ccatttatct cttcataagc agtgtaaccg acagtctttt cttcgctttt taataaaaag
    25321 taggacacac cttctgtcag ttctttttga atctgttttt ttgactgata agttttcagc
    25381 atgtaatcca cttgtttttg accaatgatc ggcacaaaag cttccggcca tacttcttgt
    25441 atgactgcca tcagctcatc cagttcattt tctgttactt ttattttttc catacaccca
    25501 cgtccttttt tacattataa atgaccttgc gcttgatgga ataaaaagag catgatcatg
    25561 ctatacacac ccaccgacca tggtttcaag aaaatcacaa tctgcataaa ttccctaaaa
    25621 gataatttcg tcaaaccagc tactagacag atcaagtcgt ctggcgcaaa gggaagcagc
    25681 aaggtaacaa ctagtacttt tttaatatct ttcgtttttc ttgtcagcaa ttcatcaaat
    25741 ttctgatact tttttggcga taaaataagc tggacaaagg ctacgccata gtaacggaca
    25801 agcaaaaatc cgattgcttc cccaatcact aggccaatac aactatataa aagcccaaat
    25861 ccattgccaa acatcagcat gcccgctact gaggagatcc ctcccggcaa aataggaatg
    25921 atcacttgga tcacttgcaa cagaacaaat atcatcactg catacttgcc aaattgctgg
    25981 ataaacgctt gcaaagacgt gctcgatcga aaaatcccat gatgataagc ataaagaatc
    26041 aacacaaaga aaaaaaacag accaataatg ggcatgatct gaagacattt ttgtaaaact
    26101 gatccttttt tagacatcta tattccccac atcttttttc atttattaaa actgcctcct
//
LOCUS       DADGKS010000033        25652 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.033, whole genome shotgun sequence.
ACCESSION   DADGKS010000033 DADGKS010000000
VERSION     DADGKS010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25652
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.033"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(530..2026)
                     /gene="lysS"
                     /locus_tag="JXV47_001536"
     CDS             complement(530..2026)
                     /gene="lysS"
                     /locus_tag="JXV47_001536"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HAX1487587.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(2137..3141)
                     /gene="dusB"
                     /locus_tag="JXV47_001537"
     CDS             complement(2137..3141)
                     /gene="dusB"
                     /locus_tag="JXV47_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HAX1487588.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(3142..4029)
                     /gene="hslO"
                     /locus_tag="JXV47_001538"
     CDS             complement(3142..4029)
                     /gene="hslO"
                     /locus_tag="JXV47_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HAX1487589.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(4246..6357)
                     /gene="hflB"
                     /locus_tag="JXV47_001539"
     CDS             complement(4246..6357)
                     /gene="hflB"
                     /locus_tag="JXV47_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HAX1487590.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     TNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6447..6992)
                     /gene="hpt"
                     /locus_tag="JXV47_001540"
     CDS             complement(6447..6992)
                     /gene="hpt"
                     /locus_tag="JXV47_001540"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HAX1487591.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6992..8437)
                     /gene="tilS"
                     /locus_tag="JXV47_001541"
     CDS             complement(6992..8437)
                     /gene="tilS"
                     /locus_tag="JXV47_001541"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HAX1487592.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8557..9027)
                     /locus_tag="JXV47_001542"
     CDS             complement(8557..9027)
                     /locus_tag="JXV47_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HAX1487593.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(9073..9498)
                     /locus_tag="JXV47_001543"
     CDS             complement(9073..9498)
                     /locus_tag="JXV47_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HAX1487594.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9565..9834)
                     /locus_tag="JXV47_001544"
     CDS             complement(9565..9834)
                     /locus_tag="JXV47_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HAX1487595.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9845..11440)
                     /locus_tag="JXV47_001545"
     CDS             complement(9845..11440)
                     /locus_tag="JXV47_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAX1487596.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGVALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11455..14976)
                     /gene="mfd"
                     /locus_tag="JXV47_001546"
     CDS             complement(11455..14976)
                     /gene="mfd"
                     /locus_tag="JXV47_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HAX1487597.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14993..15553)
                     /locus_tag="JXV47_001547"
     CDS             complement(14993..15553)
                     /locus_tag="JXV47_001547"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HAX1487598.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15906..16880
                     /locus_tag="JXV47_001548"
     CDS             15906..16880
                     /locus_tag="JXV47_001548"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAX1487599.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            17050..18450
                     /locus_tag="JXV47_001549"
     CDS             17050..18450
                     /locus_tag="JXV47_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HAX1487600.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18528..19250)
                     /locus_tag="JXV47_001550"
     CDS             complement(18528..19250)
                     /locus_tag="JXV47_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAX1487601.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19329..19835)
                     /locus_tag="JXV47_001551"
     CDS             complement(19329..19835)
                     /locus_tag="JXV47_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAX1487602.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19958..21757
                     /locus_tag="JXV47_001552"
     CDS             19958..21757
                     /locus_tag="JXV47_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HAX1487603.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21825..23399)
                     /locus_tag="JXV47_001553"
     CDS             complement(21825..23399)
                     /locus_tag="JXV47_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487604.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23654..24163)
                     /gene="mreD"
                     /locus_tag="JXV47_001554"
     CDS             complement(23654..24163)
                     /gene="mreD"
                     /locus_tag="JXV47_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HAX1487605.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(24167..25021)
                     /gene="mreC"
                     /locus_tag="JXV47_001555"
     CDS             complement(24167..25021)
                     /gene="mreC"
                     /locus_tag="JXV47_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HAX1487606.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVNPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(25176..>25652)
                     /locus_tag="JXV47_001556"
     CDS             complement(25176..>25652)
                     /locus_tag="JXV47_001556"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HAX1487607.1"
                     /translation="EEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLI
                     GATGGRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLA
                     YCCLTPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
BASE COUNT         7084 a         5530 c         4634 g         8404 t
ORIGIN      
        1 gagtgtttcc cgattcattt ttggctgccg tagcaacttt tatatcatat cagagagaca
       61 agcgattgtc aactcttttt taaaagtttt tttcgatttc gtttttcgaa atctttcggc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcgt
      241 tagtaacatg tcaataactt ttttgttatg tttttgaata aatattttct tctgtctttt
      301 ggacaagtaa taatatacca actaaattta gcttggtcaa cgaatttttt gtattttttc
      361 aagttttttt caataaacga ttattcataa cttttctttc tttatcgttc gttttcgtct
      421 tctttaatgt ctagaatagt cggcattagc ttttgaactt tcgttattat ttattccttt
      481 ctacacagca aaagctgcct aaggaattcc ttagacagct tttattcgat tatctcattg
      541 ttgggaatag caaaacatcc cgaattgatt gtgcatcagt tagcaacatt actaatctgt
      601 cgatcccgat gcctagacca ccagttggcg gcataccgta ttctaaggct tccaagaagt
      661 cttcgtctac accgtgagct tcgtcatttc ctagttcacg ttctttttct tgcgcttcga
      721 atctttctct ttgatcaatt ggatcgttca gttctgtaaa ggcattagca aattcgcgcc
      781 ccactatgaa tagttcgaat cgatctgtga atcgaggatc ttctggattt ttcttcgcta
      841 aaggcgaaac ttcgactgga tgtccgtata caaacgtcgg ttgtgtcaat gtttcttcaa
      901 caaatgtttc aaagaattca ttgataacat gtccgacacc catagcttcg gttacttcta
      961 cattgtgttt ttcggctaaa gctaatgctt cttccaatgt catttcttgc cagaagtcta
     1021 caccagtttg ttctttgatt gcatctacca tatggatgcg tttaaagtca ctttctaagt
     1081 cgacagcttg tccatcatat gtgatttttg ctgttcctag tactttttca gctgcgttac
     1141 ggataatacc ttctgtcaga ttcattacat cattgaaatc agtatatgct gtgtatgctt
     1201 ctaacatcgt aaattctgga ttatgtgtag tatcaattcc ttcattacgg aaaacgcggc
     1261 cgatttcata aactttttcc attccgccaa caattagtcg ttttaaatga agttctagcg
     1321 caatacgcaa atataaatca atgtccagtg cattatgatg cgtgataaat gggcgtgcgg
     1381 cagctccacc tgcctcattg tgcaatactg gtgtttctac ttcaatatag ccattgccat
     1441 ctaaatagcg acggatttcg ctgataattt ggcttcgttt cataaatcgg tcaaagcttt
     1501 cgcgattact gattaaatcc aagtagcgtt gtctgtagcg ttgttcaata ttcgttaagc
     1561 catggtattt atctggcagt ggacgaagtg cttttgacaa aatcgtgatt tctgaagctt
     1621 tgatagaaac ttcgcctgtg tctgttttca tgatttgtcc agttacacca aagaaatctc
     1681 caaggtctgc atgtttgaat acttcatagg cctcatcacc tacttggtct tttcttacat
     1741 aaatttgaat ttggccttca cgatcttgta gatgcgcaaa tccagctttc ccttttcctc
     1801 ggcgagtcat catacgacca gctacactag cggtcaatcc catttctgct agttcttctt
     1861 ttgttcttgg atcaaatagt tcatgcaatt cttctgagtt gtgcgtgcgt tcaaatcgtt
     1921 ttccaaatgg atcgattcca tcttcacgca attgttccat tttttgacga cgtacaagca
     1981 tttgatcatt taaatcttct acttgatgtt gttgttcctg tgtcacaaaa gttcctccat
     2041 tctcatgtta atctctttcc tataatgcca atgaaacaca aaaaaagcaa gccgaacttg
     2101 gaatttcggc ttgaaaattc acgaaaaact tagaaatcac aacgtttgtt tcaatagtac
     2161 tttttccgct ttttctacaa attgatccag caggtcattg atttcttgct gtttttctgt
     2221 ctgattgatt gctactttca ctttcgctgc tcgaggaatc ccttttaaat aataagccgc
     2281 atgtgttctg aattctctac aagctacttt ttctcctttg agatctgcta agcgttgtaa
     2341 atgaagttta gctgtagcaa ttttttcggc tggtgttggt tcaggaatca gttctcctgt
     2401 ttcgagataa tgctgtgtgc ggtgaatcat ccatggattg cccagcgctg cacgaccaat
     2461 catcacaccg tctgcaccga catagtcaag catccatttt gcatcttctg gcgttttgac
     2521 atccccgttc cccataaatg ggatcgtcaa atgttttttc acttctttca atacttccca
     2581 gtccgctttt ccttcataca tctgaacccg tgtacgtcca tgcatagcga tggcacttgc
     2641 tccagctgat tgtgctgcta atgcattttc tacagcaaag acgtgctctt catcccaacc
     2701 aatacgcatc ttgattgtta ctgggatatt tactgctgaa gaaacagctt ggaccatttc
     2761 gtatactttc tcaggatcta aaagccattt tgctcctgct tctgctttga ttactttatt
     2821 tactggacag cccatattga tatctattat atcggcagct gtgttttctt cgacaaattg
     2881 agcagcttca actagactat ctttatttcc gccaaatatc tgtaaactta atggatgttc
     2941 tgtttcttca atgtggagca tctctaaagt ttttttgttt ctgaaatgaa taccttggtc
     3001 actgatcatt tcacatacga ctaagcccgc accaaattct ttgacagtga ctcgaaatgc
     3061 tgaatttgtt attccagcca tcggtgcaac aacgacacga ttagggattt ccacattgcc
     3121 aattttccat gtgtgttcca cttaaatccc tcctaaggct tctttcttca atccatctaa
     3181 ttcttcttcg ctatacttgt atttgttatt acagaaagaa caaaccgctt ctgcaccgtg
     3241 atcttcgtct atcattgctt ggatttcttc tgcacctaac gcgataattg cttctgcaaa
     3301 tttttctttt gaacagtcac atttgaattg aacaggcatt ttttccaaaa tgttcaattc
     3361 ttctgtacca agcaatcctt tcaatatttc ttctggtgtc tgtccttcat ctaagagggt
     3421 agagattctt ggtgtcgttt ttaattgttc ttcgatcttg ctgattgttt cttcatcggc
     3481 acctggcatg atttggatca tgaatcctcc cgccgtcttg atgctgtcgt cagtattgac
     3541 caatacactc agtccaacag ctgaagggat ttgttctgag atagcaagat agtaagtaaa
     3601 atcttcagcg atttctccag aaacaatcgg cgtttgccca gaaaaaggtt cttttaatcc
     3661 taagtctttt gtgacagtaa acattccttg tgttccaact gctccccgca catcgatttt
     3721 accttcacta tttagaggaa gactgagatg cggatttttg atgtaacctt tcacatctcc
     3781 ctttccattt gcatctacta caattcctgt tgctggacca tcgccttgga ttcgaacagt
     3841 tagtttgtct tctcctttga gcgtcgcacc aagtagcaga ctaccgacca atgtccgtcc
     3901 caaagcagct gaggaggtgt gccaagtatc atgacgtctt tgtgcctccg ctacggtatt
     3961 tgttgcttga acggcgtatg ctcggacgaa tccgtcgtga gcaagtgcct taaccaaata
     4021 atctttcatt tgttatgtac tcctttttcc gtttttaaac tcatagtgaa tcatactagc
     4081 aactactgct tttttcaact ttggaatgct tcttttaaaa ataattcaga atcatctaga
     4141 aaacaggaca tcaccctatt tacaacttaa ataaagaaat ctcccgaaaa ccggtttttg
     4201 ttccggtttt cgggagtcat atcagatcaa ttgacctata tttttttatt tgtattgatc
     4261 gtctgaatga ttatcttctg attgttgaga atctgaatca tgttctgctt tattttcctc
     4321 attcagttca tgttttgctt cttcaaaatc acgtttttct tccgcttgtt tttcagcgtc
     4381 tttttcttcc aaagcacgtt ttgcttcttc aaaagttttc gcttcttttt cgcttggata
     4441 atcatttgac tcagtacctt caggcatcac accgtgttca aacaatgact tgattgcttt
     4501 ggcatccaat gtttcgaatt ccaaaagttt ttcagcaatc agtttatgct gtgcacgatg
     4561 agcttcgatg atttctcgag ctttatcatg agcttccatc aagatttttc gtacttcttg
     4621 atcaatctcg aaagcgactt gttccgagta agcttttgtt tgaccatagt cgcggccaac
     4681 aaacacttga tggtttcctt catattgaac aggacctaaa cgatcactca ttccatattc
     4741 tgttaccatg cttcgtgcta gagctgtcgc ttgctcaaag tcattggaag caccagttga
     4801 ttggacattg aagatgattt cttcagctgt acgtccacca agtaagccta cgatttgttc
     4861 aaacatatct tctttcgtca tcaagaactg atcttctttt ggtaaagcga tcatatatcc
     4921 gccggcgcgt ccgcgaggga tgatcgttac tttgtggacg acccgagcgc gactcaatac
     4981 taatccgaca atcgtatgac cagcttcgtg ataagcaacc atttcgcgtt cttttttgct
     5041 gattacgcga tcttttttag ctggacctgc aatcacgcga tcttccgctt catcgatatc
     5101 agaagcatcg attttctttt tatttcttct agcagctact aacgctgctt cattcaagac
     5161 attttctaaa tctgctccgg caaaacctgg tgtctgttga gccacaactt tcaagtcaac
     5221 gtcatctgcc atcggtttat tccgtgcatg gactcgcaag attgcttcac gaccttttac
     5281 atctggacgt ccaactaaaa tctggcggtc aaaacggcct ggacgtagta acgctgggtc
     5341 tagtacatca gaacggttgg ttgcagcaat gacgattact ccttcatttc cgtcgaagcc
     5401 atccatttct acaagcaatt ggttcaatgt ttgttcgcgt tcatcatgtc cgccgcccat
     5461 accggcacca cgttgacgac ctaccgcatc aatttcatca atgaaaatga tagctggtgc
     5521 gtttttcttc gctgtttcaa acaaatcacg aacacgactt gctccaacac cgacaaacat
     5581 ttctacgaaa tcagaacccg agatcgagta aaacggtact ccagcttctc cggcaacagc
     5641 ttttgctaat aaggttttac ctgttcctgg aggtccttct aaaagtacac ctgccgggat
     5701 acgggcacct aattcaacaa atcggcgagg atctttcaga aattcaacaa cttcaactag
     5761 ttcttgtttt tcttcttccg cacccgctac atcagaaaaa cgtacgcgat tagctttttt
     5821 gtctgcttct ttggcttttg atttaccaaa gttcatgaca cggccgccac cgccaccgcc
     5881 gccgccttgt tgtcccatca tcatgtaaaa gaaaaagatg atgattacga ttggcaagaa
     5941 gctaagcaat agggaaaccc atataccgct gcttgattct tcttttactg ttgtagcaac
     6001 tttgttttct tttgccagtt ctgttacttg gctcaatgtt gtatcatttg tcaaaatgat
     6061 tgttgtgaaa tgggtagtag tcgtatctgt tgaacctaag atagctaacc caccgctgtt
     6121 agcgacggtc tgctgttctt tgtattcacc agtgatctta tatacaccat ttgcaggctg
     6181 cacttcaaat tctttgatct tgcctgcttg tagttgttct gtgaattttg agtactcgat
     6241 atctgacgat cgctggccgt tattaccaaa aatgaaataa acgaccatta ccatcgctaa
     6301 gattacgagg acataataca aggcattttt catcatgccg ttgttctttt tgttcatagt
     6361 tgccctccct aagcgtcaat ttaatttaac agttttttat caatcctgac cattctattg
     6421 taccataatt taattgagat acagcattaa tttgattgat aaacactagg tttcaataca
     6481 ccgatgtacg gaaggttacg atatgcttct gcataatcca agccataacc gaccacaaat
     6541 tcatttggta cgttgaagcc aacataatct gcttcgatat ttactactct tccttcaggt
     6601 ttgtcaagta gtgtaacaat tttgactgat tttgctttgc ggtatttgaa aagatccact
     6661 aaataagcaa gtgttcttcc gctgtcaatg atatcttcaa cgatcaacag atcgcgacct
     6721 tctacattcg tatctaagtc tttgacgatt tttacttccc ctgacgagac tgttgcattc
     6781 ccgtagcttg aaacatccat gaaatccaat tccaaatacg tatcgataga acgaacgata
     6841 tctgccatga atggtaccgc tccttttaag acacctacta ctaggggatt ggtgttttgg
     6901 taaatttctg ttaactcttt gcctagttct ttgcaacgaa cttgtatctc ttcttgtgag
     6961 atcaaaattc tctcaatatc cttttccaac atcaggttct ccttccaatt gcttcttttt
     7021 gatatttgta aagaagtatg tagtgtattt tatcagtttc ttcacgaata ctcaaatatg
     7081 aaaaggcaaa aggtatcaag ctatatatat ttcttttggc atctgtaatg atccaagcat
     7141 gctgcctttg tgaattaggt actttctgat cgataaaata tctagatact ttttttgtga
     7201 gattctctgt taatttaatg cggtctcctg cttttctttt ttcgacatac agttgcacat
     7261 cagcaggaat ccaaatgtca tgagaaaata gagaccatga atctgttgct ttgatgtccc
     7321 ctgcattttc aggtttgacc agaccaatcc attctgtttc attcaaatat attccttgtt
     7381 ctggaatcag caacaagcgc tggtcttctg tctggctagt tgcttgtttt tcttttttag
     7441 agagtacaac aaaatgatac tctcttttca gtatccaatt attgccaata ctgagttgcc
     7501 attggctttt tttctgttgc cactggtcta aaatcgactc catttgttgt tctttcaaaa
     7561 taattcctgt ttttgagaat gctttgtcga aaaaggagta aaaaaaatag tatcgttcag
     7621 catctgtcat ttcttcaatc atttctgcag aaaatcgaaa ttgttcctcc cactgttcga
     7681 cttccttttc gatcaactgt cccatatatt tttgaatgac ttggtctgcc cattggatct
     7741 gttgcgaaaa ttgctggaaa tgtctcaacg cctgtgtatt ttcttgtttc aattgaggaa
     7801 ctaccaaatg acgaagccga tttctctgga tatctaacaa ttggtttgtc tgatcctcaa
     7861 agtaaacaag ctgcgattcc gctgcataag tatataggtc ttctttgcta aaactcagca
     7921 acggacgaat cagtctgccc gtagcaaatg gttgtacttc tttgattcca gaaaaagtat
     7981 ttaactgtcc cccacgaacg attttcatta acaccgtctc gatttgatca tctccgtgat
     8041 gagcagtcat caacgtgtca tattgtcctt cttccatcac gcgagtgaat tcttgataac
     8101 gaaagttacg agcttctgtt tctatggcgg atttggctgg atcttcccaa atacttacat
     8161 ataaagggag attcttctct tcacaatatg agcgaagata ggcagcttct tctgctgatt
     8221 cttctcttaa ttggtgattg atgtggacga tacctaaaga aaaaccgatt tggcgttgca
     8281 cttgtaaaag taaatggagc aaaaccatcg aatcaacacc acctgatacc gctgctaaaa
     8341 ttctcgatcc ttgttgccag aatccttgtt cattcccgtg ccgaataaat gactgctgta
     8401 atagcggtgc ttttttcccg cctttttcaa cgttcatcct ttccacaccc tttcttccta
     8461 aaaaaaagag agcgggaaaa cgtctaaaac gacaattaac ctgccctctg ttgatactat
     8521 gacccaaata gtcgcactat cattatttgc ggctttttag ctgcgacgtc cgccacggcc
     8581 accgcgcttt ccttctgtgt ttcgcttcaa tgaagataag cggtcatcgc tatctttcaa
     8641 aaatgaactc atcaatgaat cgaagtcttc tttttgagct gaaggttgac tgcgagaaaa
     8701 agattttttc tgtgctggac gatttcggtt gtcacgggga tctttttgtt gatatttttt
     8761 aggacggctt tcttctccag attcagcagg ttgttcctgc gctttccgga tagatagtcc
     8821 gatttttcca tcatcattta ctgaaataac tttaactgtt acttcatctc ctacacttaa
     8881 aacatcatgg atgtctttta catagccatt tgacacttcg ctaatatgaa ctagacccgt
     8941 ttttccagca cctagatcaa taaacgcacc aaaatttgtg attcctgata cttttccttg
     9001 cagttttgct cctacctcga ttgacataaa aaaaatgttc ctcctaatta tttccctttt
     9061 ttatattcct gcttattttg cagttgtaga actagttgat tgatctgttt catttgtcga
     9121 gctgtctgta tttgattcta atataggata aactttttca ccgtcttttg agtaaaagaa
     9181 tttgcttctg gcaagtttag ctacatactc atcatctttc agcaatgaaa catcttggtg
     9241 cagctgatca acgtctgcgt tgacttcttt catttcagta tttgcttcga ctctcaattc
     9301 gttcaattga tgcatccttt gcatgtcatg gaaaatctgc acacctatta tcgcgaaaat
     9361 gaccaaagca ccaacaaaaa ttgcagccag tctgcgtctt cgaaaaatca gttgacgttg
     9421 ttgttgctga aattcagcat actttttctt tgcatattcc gtatctagcg cagcgatttt
     9481 attgcttttt ttcgtcactt ggattcgctc caatcttttt gattgtcttt ttcattatac
     9541 caatatcgtg aaagcttgtc taatctattt ctctagtgtt tctgtgcgat tttcagaaat
     9601 aatttcgtac attttttgtg catcttcttt tttggttgat tcatgtaatt ccgtaatttt
     9661 cacttccaac gttttgttgc caaactggac tttcaaaata tcgcctactt tgacatcact
     9721 ggaagatttc gccaatttac cgttgatttg aattcttcct ttatcagcta cttcttttgc
     9781 tactgatcgt cttttgatga ttcgggaaat ttttaaaaat ttatctaatc gcatatctta
     9841 ttcctcactt tttaattttt ttatttaatc gcaggatttt cttaccaaaa ggcaacatta
     9901 gccattctcg tactgtaaac agacgaagac gaatcactgc ataaatgaac acagaagccc
     9961 cgatcccaac tcctatcacg ctgacaaaaa aagcagtgga acgatgagtt acaggaccaa
    10021 atactatatt caatacacca taatacagca gcagtactac tgtcatacaa agaaggctga
    10081 acatcaactt ccgtccaaaa tgccgttctt tccaaaaagc atttagctct tttgtttcaa
    10141 ttcgaacaaa ataccaaagc gtcacaccta atcctaaaag ggtagacagg cttgcacctg
    10201 ctgttcctaa taaaccggtc agaaaagaag tagtcaatcc ttttaccaat agtccccatc
    10261 ctgcgccttt taaagaaggg cgaaacgagt tcttgctttg agcaatactt tgataagctt
    10321 ggatgactgc agtgaaagca atggaaaaaa caaataatac aagcgctgca tttcccgcat
    10381 aatctttaaa caacgcataa ttgatataag ggagcagcaa ggctaatccc aaagacgcag
    10441 ctaatgctaa agcggtcgtc aatctaagat agattttggc tgtctgtaaa aactgacgat
    10501 agatccggtt ggtcaaatga cgagtcaacg caggcaggaa tgtcgcactt aatgcagtgg
    10561 caatcactaa acctaattgt actaaaggct gacctcgatc atagacccct tttgctatct
    10621 tcgcaccgta ttctgacagt ccgtaaactt ccaaagcatt ttttacaaag aaagagtcga
    10681 tcagctggaa aaagataagc aatccactat aaatcgaaac cagtccgcct tctaccagaa
    10741 aacgccggat caagggcttt gacggctgtt tgaacaatgg aaaccgtcgg aagcttaacg
    10801 ctactccatg aatcttttgt tcatagtagt gaaggatccc atatgcgcat aaaccgccaa
    10861 aaacagctcc actcattgct gccgtccctg tttggtacac cgtccatcca agctttctaa
    10921 aagcaaacgc actacagaca atcacaaaaa cacgaacgaa ctgctcaact acttgagaaa
    10981 cagcagttgg ttccatcaag aatcttcctt ggaaattccc tcgataaaaa gatagaccag
    11041 gcatcagcaa aaaggtaaag gaaactactt ggatcagcgg tttcaattgt atgtctccca
    11101 tcatccaagc aatccagctg ctaaatgcaa agacaaacaa ccacaaaaag acacctgtcc
    11161 aaaatactaa gggataaaga ttttgcaaag cttgctttcg ctcgaaagga ttctttcttt
    11221 ctgcaacgta ctttgatatg aactgcggaa gaccggataa agctaaagtc attgctatcc
    11281 cataaattgg ataaacttgc tgataaacat aaaaaccttc gtcgccgact aagttttgga
    11341 ggggaattcg gtaaagggca cttaatactt ttgctatgaa agaagcaatc gtcaatacaa
    11401 atgctccttg catgacgcgc cgcatttctt tatgatccaa atcattgctc cttcctacgc
    11461 tgacagatat ttttgctcac gcaacgcttt gacaaacttt tggatttcct gaagccatac
    11521 tgcttcttcc atttggttgg ggatcgtcaa gcgtatcacc atctgttctt tttcaacgcc
    11581 tagactggct tttagttttg tcgctgtcag tgcttcgaat aactgttcca cactatagcg
    11641 ttttgttcca actttactta gagtaaagac tatatgcgcc tcctgtttcc ttatcgtttc
    11701 taggagcgct cgatcgccat ccattttgat ctgcccaatt gtcaagagat gtgctacttc
    11761 ttctggatat tctccaaaac ggtcgagcag atcatcttct agttcatcta gcatttcttg
    11821 cgaatcaagt tcacgaattc gtttatagat ctcgattttc tgccgttgat ctgccacgta
    11881 tgtttcaggt agatacgcat cgacaccgag gtcgatctca acagtggtct tctccacttg
    11941 actattcttt ccttgtttac gagaaacagc ttcgcttagc atttgagaat acatatcgaa
    12001 accgactgca tcaataaatc catgctgctg agcacctaag agattacctg caccgcgaat
    12061 ggaaagatcc cgcatcgcaa tcttgaatcc agatcccagt tctgtaaaat ctttgattgc
    12121 ctgaagacgt ttttcactga cttcgttaag gatcttctgc tgctcataca taaagtaagc
    12181 atatgcgaca cggctgcttc ttcctacccg ccctcgcaat tggtataacg tggataatcc
    12241 catataatca gcgttctcaa cgaacaacgt atttgcgttc gggatatcta ctcctgtttc
    12301 aatgatggtt gtagtgacaa gaacatcata ttgaccttca ataaattcaa aaagcgtatt
    12361 ttctaattgc gcctctgtca tttgcccatg agcataaccg atccgtgctt ccggaacgag
    12421 ttcttggatt tcttctactt tttgttcgat cgtttctacc cgattatata aatagaatac
    12481 ttgtccacct cgtcccattt ctcgatggat tgcttcgcga atagccccag gatttttttc
    12541 cataacatac gtttggatcg gataacgatt cgcaggcggt gtttcgatta ctgaaagatc
    12601 ccgcacgcct aacatcgaca tatgcaaagt tctcggaatc ggtgttgcag tcagagtcaa
    12661 aacatccact tgtgcacgta actgtttcaa tcgttcctta tgttttacac caaaacgttg
    12721 ttcttcgtca atgatcagta gacccaaatc gctaaattca atatcttttg acaaaattcg
    12781 gtgggttcct acaacaatat caacttgacc tgtacgcagt tgttcgatgg tttctttttg
    12841 ttgctttctt gttctgaaac gacttaatag cccgatattt acggggaaac cttcaaatct
    12901 ttccagcatc gtttcatagt gctgctgtgc caagatcgtt gttggaacta aaaaggctac
    12961 ttgtttgctt tcctttatcg ctttaaaggc cgctcgaagc gctacttctg ttttcccata
    13021 accaacatca cctacgagta gtcgatccat tggtttttct ttttccatat cccgtttgat
    13081 ctccgctgca cttctcaact ggtcatcagt ttcagagtag gggaaggcat tttcgaattc
    13141 tttttggtag gcgtcatcag gtccaaaagc atatcctttt tctgactctc ttgcggcata
    13201 taatttgatt agatcgtcag cgatatcctc gatttttgaa gagacttttc gcttggtttt
    13261 cgtccattca cttccgccta gcttattgat gcgaggcgct ttggcttcag aggcgacata
    13321 tttttggatc agattcagtt gagtaacagg aataaacagt ttgtcgtcgt tttgatacaa
    13381 aatagtcata tagtcttggt gaacgccatc tacttctagc gtttccatcc caatgtattt
    13441 cccgatacca tgattggcat ggacaacgta atctcctgct tttaactcat tatagctttt
    13501 caatcgctct gcgtttgtta ctgtttgacg tctcgtttgt tttttcgtcg ttttttggaa
    13561 aatttctttt tctgtgatag ctactatttt ttcttgagga agttcaaaac cagcctgcaa
    13621 agctccttca actaattgta cctgtcctct gatcaatgca tttttttctg tttctactac
    13681 taatatgtct tcatctcgaa gcatttgttc tgctttgcgt attctgtcct ttgtcggaat
    13741 aaagatcaca acagtctgtt tttgcttgcg ccaacggtcc atttctgttt tcagcaatgg
    13801 catttgtccg aagaactgtt gcatcgtccg atattgaaaa ttatggattg cttggaaacg
    13861 aagatttccc atcccttttt ggaagagtga gaaaaaggtt gtggtgaact tttccttctg
    13921 cacgattttt tgtatatctg ctgaaaatgt ctgctcagaa aacacccgca attcgctgat
    13981 tttttgagtc tgccattctg ccgcttccct ttcgatttcc cgatttgttt ccatgattcg
    14041 ctgataatca tcaacgacta gtaaactatt tgaagggaaa taatccaaga tcgtcacaga
    14101 ttcttggtaa agaagatctg agtagaattt tgcttcttct gtcgggacac ctgcttgcca
    14161 gcttgaagtc agctgaccga agtaatcttg caaaaactcg cggtctgctt cttctgtggt
    14221 cgcagcaagc cgtttttcta gcattttttg catttgctct attccatgtt ctagatcctc
    14281 tggtccgtag acttgttcac tcgttgggga aacccagatt tcttccgttt tttcgattga
    14341 gcgttgtgtt tctgcttcaa aataccgcat agaatctatc tctacatcaa atagttctac
    14401 acgaacagga taggttgtcg ttaacgggta aatatcgata atgcttcctc gaatactgaa
    14461 ttctcccggt tttgcgacca tctcttctcg tacatagccc atcaaagtca attggcgagg
    14521 aagattttcc acgtctatct catcaccaat atgccaattc aattgcgcct gtagccaagt
    14581 tttcttattc ggcagtcgtt tgtgcaaaga tgcgactggc aacaaataga tacctgcttt
    14641 tttttcttga agtgcgttaa gcgttgcaac tctctcgcct cgcgcttctg gagaagaaaa
    14701 ggccatttca gcagaaagca cttcatccac tggaaataaa tggatctgat cttgcggaat
    14761 cacatgttgc agatcttctg ctaactgatt cgcataatac aaatttggca tcagaataat
    14821 catgttttta tttgttttct taaacgctcg agcaaataga agtgttttcg ctgagcccgc
    14881 taatcctgtg attagttgtc taggcatttt ttcttctaaa ttgctgaccc attcttttac
    14941 ttgcggatct tttccgacta attgaataat atccattcct tttcctcctt cctcaattga
    15001 atcgattcat cgcatccacg aacgaatgcc cttctatgag atattcgact gctttaacag
    15061 attgacacat gctttcttct atcaaaggct gattttcttt gctgaaagga ctaagcacat
    15121 gctggactac tgtttttttc ccttctggcc tgccgattcc caccttgatt cgatcaaaga
    15181 cattcgtatt caaatgggaa ataatacttt tgataccgtt atgcccgccg gcacttccct
    15241 tttgacggag ccggattttt cccactgcca gatccaaatc atcgtagatt acgactaatt
    15301 cctctggata aatcccaaaa taagtcatta gtgggccgac tgcacgacca gattcattca
    15361 tgaatgtttg tggtttgact aaaaggatct tttctccatt atgaaaaaat tcggcaactt
    15421 ctgcttcgaa cggatttttt ttgaaagtag cttgatgctc gcgtgcaatt ttatccacga
    15481 ccataaagcc gatattgtgt tttgtatatt ggtatttggt acctgggttt cctaacccga
    15541 cgatcatttt catttttgtt ttccacctaa ttctaaaaag cagcacaaaa ggctggactg
    15601 ctaattagcg gtccagtcca tcgagctttt ttctttttta tacttgtcaa tgcatagtat
    15661 aacacaaaac aaggcgtttc ggctaaaaga gaatcgttaa taaatgataa agaaattaaa
    15721 aatttcttca aagtttaatg aaataattga tatataaaaa tagtgaaata acgcacatgt
    15781 aagctttttc atataataca accttgttat ctgttatatt ttatagccaa atagcgtgac
    15841 atggggcttg agaaatgtta gcataagcat gggaaaaaac aaatcaatgg aaggattgat
    15901 actaaatgac tgcagctgca gaaaaaaaag atcatcaaaa agttattctt gttggagacg
    15961 gcgccgtagg ttctagctat gcctttgctc tagttactca aaatatcgct caagaagtag
    16021 gtattgtgga tatcaatact gctaaaactg aaggagacgc aattgacttg tctcacgctt
    16081 tggcatttac ttcacctaaa aaaatctatt ctgctactta cgcagacgca catgatgctg
    16141 acttagttgt tattacagct ggcgcaccac aaaaaccagg tgaaactcgt ttagacttag
    16201 taaacaaaaa cctaaaaatc aaccgcgatg ttgtcacaca aatcgttgaa tcaggattta
    16261 acggtatctt tttagttgcc gctaacccag tagatatttt gacttactca acttggaaat
    16321 tctcaggttt ccctaaagaa cgcgtaatcg gttcaggtac ctctcttgac tcagctcgtt
    16381 tccgtcaagc acttgcggaa ttagttgacg ttgatgcacg taacgtccat gcttacatct
    16441 taggtgaaca cggagattca gaattcccag tttggtcaca tgcaaatgtt gccggcttgc
    16501 aaatctatga atgggtaaaa aacaacccag aaatcgatga agaagctatg gttaacctat
    16561 tctttggcgt acgtgacgct gcttacacaa ttatcgagaa aaaaggcgct actttctatg
    16621 gtatcgcagt agcattagca cgtatcactc gtgccatctt agatgatgaa aatgctgttc
    16681 ttcctttatc agtattcatg aatggcgaat atggattgaa cgacatctac attggtgcac
    16741 ctgctgttat caaccgtcaa ggtatccaaa aagtaatcga aattccttta agtgacagcg
    16801 agcaagaccg tatggctgct tctgctaagc aattaaaaga aattctagat gaagcttttg
    16861 ctaaactaga cgctgaataa tctttgaaca tgacggaaaa catctattcg gtgttttccg
    16921 tttttttatt ttatcaccct tatggtttct aaattttttc ataaagtaga gataaccttc
    16981 gtcttttcct ctaaattatg ctatcatgag accgttccac cctaaacttt tacttaagga
    17041 gttgtcgata tgacaagatc ttcgcatcga aaaaaatcga aacatgttgc tttgctttca
    17101 gttcttggtg ttctcttagt gctgatcagc ttttatacct atcgcagtac atactacaca
    17161 aagcattttt tgccgaatac agaaataaat ggaataaatg tcagcaatct aacagtcgaa
    17221 aaagcaaatg aaaaattaaa agaagcttat tctgataaaa aactggctat taaagaagat
    17281 ggaaaagtct ggcaggaagt accaaaatcc gagctcggct acaaagatga tttcacttcg
    17341 gagctttctc cgatcctaaa tgaacaaaac ggatggactt ggggaatgac ttatgtctca
    17401 gcggcagaaa aacaagaaat agatcctgtc agtcaaaacc accaaaaact agacactacc
    17461 gttcagacat tgacaactaa gctgactgat ttgaacaaag accggacacc tactactgat
    17521 gcaacgatcg aaaaagcagg tgactctttc gttatcaagc ctgaagtcaa tggaaatacg
    17581 atcgacgtcg atgctgcggt caaacaatta aaaagtgcgg taaactctgg taaagataca
    17641 attgaattga ctgaattcaa agaaaaacca aaagtaacat ctgaagacag ctcactgaaa
    17701 gaacaactcg catccatgaa tgctatcgca aatgtaaaag ctacttacag tataaacggt
    17761 gagactttcc agatcccatc aagtgatatt atgagttggc tgacctacaa tgatggaaaa
    17821 gtcgatttag atacagaaca agtacgtcaa tatgtaacag atttaggcac aaagtataac
    17881 acaagtacga atgacacaaa atttaaaagt acaaaaagag gagaagttac ggtcccagtt
    17941 ggcacttaca gttggacgat ccaaacagac agtgagacag aagcattgaa aaaagcgatt
    18001 ctggcaggcc aagattttac tcgttcaccc attgtgcaag gtggcacaac cgctgatcat
    18061 ccattgatcg aagatacgta tatcgaagtt gatctggaga accagcatat gtggtattac
    18121 aaagacggaa aagtggccct tgaaacagat atcgtttccg gaaagccaac tacacctaca
    18181 cctgctggag tcttctatgt ttggaataaa gaagaagatg caactttaaa aggaacaaat
    18241 gacgatggaa caccttacga gagtccggta aactactgga tgccgattga ctggacaggt
    18301 gttggtatcc acgattcaga ctggcaacct gaatacggtg gagacttatg gaaaacccgc
    18361 ggttcacacg gctgcatcaa caccccacca agtgtaatga aggaattatt cgggatggtc
    18421 gaaaaaggaa cgcctgtatt ggtcttctaa caaaaataat atataaaaag aaagcacccg
    18481 tacgattggt acaggtgctt tctttttatt atctaacaat gtgctactta catttcagca
    18541 gcagtaaaga cttctgaaac atcatcatcg tcttctagct tatctactag acgttccaat
    18601 tgctcttttt gttcctcatt taaatcaatc gtcgtttgtg gaatcatcgt caattctgct
    18661 tgcgccaaag tgaactcttt ttccaactca tctcgtacag cagcaaaatc ttctggtgca
    18721 gtataaatct cgaatacttc aggagaagtt tgcagatctt ctgcccccgc ctctaataca
    18781 tcctcaaaca tcgtctcttc atcaacagtc aacccatcgc gttcaatagc gatatatcct
    18841 ttgcggtcaa acaagtaact gactgaaccc gtttctccca gtgatccacc gtttcgagta
    18901 aaagctactc ggacatttgt cgctgtccga ttacggttat ctgtcaatgc atggactaag
    18961 attcctactc cacccggacc atatccttca tacgtgattt catcgtaatt cgtttcatct
    19021 acggcactcg tagccttttt aatcgcccgt tccacattgt cgttaggcat atttgcagct
    19081 tttgctttgt ccacaacaag ccgcaaagct ggattcatag atggatcagg accgcctgct
    19141 ttagctgcca tataaatttc acgagaaagt ttctgaaaga ctttccctcg ttttgcatct
    19201 tgggcatttt ttcttccttg gatattatgc catttactat gtcctgacat gatttttcct
    19261 cccttgttct tttgagaata cacttctatt ctagtactat ttcacaaaaa aacaaagcca
    19321 cagccaatct ataaacgctt cttgaatgcc gcaaaaagca cacataatat cacagcagtc
    19381 agagcaccga tcgaatccaa catgacatct tggaacatag gtgttcgtcc accggtcatc
    19441 atctgatgga attcgtccaa acctgcgtac cctgttgctg aaagccaagc aaggatcgct
    19501 gtcagccacc aaatttttag cttggggaaa acacctaaaa acaagctgcc tcccaaaata
    19561 aaataggtac cgaaatgtgc gcccttcctt aaaaagaact ctaaaaattt ggcgtagccc
    19621 agatggtcga tactcaccat acttccacca taattaaaac gtatacccgc taatgtgtct
    19681 ttaaatggct gattaggcag ccagctttct aatcgcgaaa cttgtgattg ctgtccgtaa
    19741 gtttgagaag aactgtaaaa taagattata acgactatca gtgcgattac taaataaata
    19801 tttccgtttt tcatttgttt ttttgaagaa ttcataagtc acctctgtat tttatcttag
    19861 actttttttg aagaaacaac aatcattttc atagagactt cttccataaa aaagtgctat
    19921 acttaatttt gtattacaat atgaagggag ttttttcatg agttattcat taaattggaa
    19981 tctagattct attttttccg gaggcagtca ttctgatgct ttgaaccaac ggatgaagca
    20041 attggaagac caaatgaacg agtattatca ccgcgtaaca aaatggtcac ctagttctga
    20101 caatgcagag cagttaaacg ctattcttca attgcaagaa acgattacga atggttttac
    20161 ccaatgcagc agctatatta ctgcattgct ttctgccaat gtcaatgatt cagatgcaaa
    20221 ggtcttatca ggcaagcttt acgcaatgct gcctcgtctg caatcagccg aaactgtatt
    20281 gtcaaagaaa tttgcagaaa tatctgacaa tgattggaat cagatgcttt ctcaatcttc
    20341 gtttgaaaca attgcttttc gtttaaacga gattcgtcgt gatggctcac aattattatc
    20401 agaagctgaa gaaaacatta taaatacgct ttctttagat ggtctaaatg cttggagcag
    20461 tcattatgat acgattgtag ccagcatttc gattcccttc gaacaagatg gacaagtagt
    20521 cgaattatct gctggacaag ccttcaataa gatgatgggc gatccagatc caaaagtcag
    20581 agaaacactt ttcgcagcat gggaagaagc ctggaaagaa aaggcacccc tcttcacgga
    20641 tactttgaat catttagatg gttttagact ttctgactat gaacttcatg gtgtcacaga
    20701 ttttctacaa aaaccattag agtacaatcg gttgaagaaa gaaacattgt ctgtcatgtg
    20761 ggatacaatc cagaaaaaca aacaacccct tgttaattac ttgactagaa aagctaatct
    20821 tttcggtaaa gaaaaaatgg aatggcaaga tcaagatgca cctattattt taggcgattt
    20881 gaaagaaaaa acctttagtt ttgacgaagc agcagcattt attatcgaaa actttaacaa
    20941 attcagtcca aaaatggcta aatttgccca atctgctttt gaaaagagct ggatcgaagc
    21001 agaagatcgt cctgggaaac gtcctggtgg ttattgtact gagttaccag aaacaaaaga
    21061 atcaaggatc tttatgacct acagtaattc tgttaatgag gttgcgacac ttgctcatga
    21121 actaggacat gctttccata gcagcacgat gtgggattta ccttctttaa atcgcgaata
    21181 tgccatgaat gtcgcagaaa cagcaagtac attcgcagaa ctgatcgtag ccgatgctac
    21241 attaaaagtc gcaaaaacaa aagaagaaaa aatcaatttg ctagatacaa aactgcaaaa
    21301 tgctttagct atgttcatga atatccattc ccgattcatt tttgaaaatc gattctatga
    21361 agcacggcaa gaaggattag tctcagaaga taagatcaca gagatgatgg ttgaggcgca
    21421 aaaagaaggc tatcaaggag ctttagctac ttaccatcca tatttctggg ctgcaaaatt
    21481 gcatttcttt attgatgacg taccgtttta taacttccca tacacatttg gctacctctt
    21541 tagtttgggc atctatgctt acgccaacca aaagggagca aattttgaag aagaatatat
    21601 ccatttacta cgcgatactg cctcaatgac gacggaagat cttgcgaaga aacatttgaa
    21661 tgtcgatctt acccaaccag atttttggca agcaggtatc gacatggtga ctgaagatat
    21721 ccaaacgttc atggaattga cagaagaatt tatctgattt ctattttatc acaataaaaa
    21781 aagagttagt ccagaatggg ctaactcttt ttgattaatc attcttacat gctgacagca
    21841 aagtcagggg caaaccattg aactgaacca acttttacgc tttcgcctgg ttgaggagca
    21901 tggatatatt gtcctccgcc taaagcaatc gctacgtggt aagttccgcc ttgtgacccc
    21961 cagaataaca agtctccagc ttttgcttga gaaactgaaa tttttgttcc agctgattct
    22021 tgaggaactg tccaaccacc gatgtcacga ccagttactt gcatgtaaac atagcgtgtg
    22081 aaccctgagc agtcaaagcc acttggatct ttaccgcccc aaacatatgg agtaccaata
    22141 tatttgtaag cttctgctac gattgctgca ccattcacac ttccagaagg agctggagca
    22201 ggtgttacag gttttggttg ttcaggtgtt ggtgttggcg ttggagccgg agtactactt
    22261 cctgtgccgt ttcctgtatc aacactttga tctgttgatg gtgttgtagg cgcaggtgtt
    22321 gttgattctt ctgttgttga agattcaggc actgttgttg attcttctgt tgctgaagat
    22381 tcaggcactg ttgttgattc ttctgttgct gaagattcag gcgctgttgt tgattcttct
    22441 gttgctgaag attcaggcgc tgttgattct tctgttgaag attcaggtgt tgttgattct
    22501 tctgttgctg aagattgtgt agctgatgat gattcttcag tcattgaaga ttgtgtagct
    22561 gatgattctt ctgttgctga gctttgtgca gtagatgaag cttgagtagc ttgtgcttca
    22621 gcctctgctt gttcgcgtgc ttctttttca gctttttctt gtgcagcttg ttgacgagct
    22681 tgttctgcta gacgttgttg ttcacgaata cgagcttgct ctgcttcagc ttctgctttt
    22741 tgacggttca agtcagcttt cttgtcttca gcagttgctt gttcagcagc taatgaagtt
    22801 ttcagtacgt tcaaatcagc ttgtttagat aaaagatcgc ctttttgaga ttccaaagca
    22861 gcttggtttt cagctaattc ttttagttta gcatcgtttt cagctttttt gtcttctaca
    22921 gcttttttat cttgtttttg ttgttccatc aagtcgttgt ttgcttttac catcgttgtc
    22981 attgcttgaa cgcgtccaat agcatctgct aatgaatcag cattcaatac agcatcgatg
    23041 tagtttgagc ttgtgttgct tacttgtgct tcgcgtgctt gtttttggat tgtatcttca
    23101 cgtttttcaa tacgttcttg taaatctgca atgtctttta ctaattgtgc agattcttga
    23161 cgcaatgtat cttgttttgc taataggtct tgtgcttgtg tgttgatttc agaaacttgg
    23221 ctttctaagg catcgatttg tgattgtgca tctgcttgtt gatttttcaa gtctgcaatc
    23281 ttttgatctt gctgttgtat ctgagaatca aaatcgtccg ccgcggcagc gatcggtgat
    23341 gctacggcag tcaaggtcat tgaacatacc attactgctg atattaaact ctttttcact
    23401 cttcattcct ccgactggct taatttaata aatatctaaa tatatttaag tctttcttaa
    23461 cgatataaaa attgtaccat agcagtgtgt caacgatata atagttatgt tacaaaaatg
    23521 tttcaaaaca acttttaaaa atgacaaaac tgttcgtttc agaaaatgat catgaaaaag
    23581 ccgcgttaag tctagcattt cttaagataa caacgattct ttttcgcttt cgacctaaaa
    23641 ataaaaaaag aaattattca tcactgaata atttcttaaa gggaaaaatg aataatacaa
    23701 atataatcat gttcaacagc agtgtaggtc ctaaaaacct tgtaataaaa tacgtgttat
    23761 ttactactgc taatttaaaa atcaactgga ccaccatcgt aaacaattca taacccgtga
    23821 caaagatgat catactgaaa aattcagtaa agatgttgac atggataacg tctttcatta
    23881 catacatcaa ccatacaatt aaagggagag ctactgcata gataccgata acgccaatat
    23941 agtaagcgtc atagatagcc ccgagaacaa tcgtggtaat cagtaaataa cgtttttcaa
    24001 acgccatact gcaacataat aatgccaata tcagaaagtg ggcatttgac atataggtgc
    24061 ctttcgacca ctcccctagc attcttgtta aatgaccatc tatcaacatc aaaaagaaca
    24121 aaacgattgg cagatagtac ttcattgttt ctttcttcaa catggactaa tcctccgcta
    24181 gccgttggac aatcgtcaca actgacacgt catacatttc tgcataagga ttcacataaa
    24241 cttcccgatc cagcccataa ctatctggtt tcgttttaat aaccgtaccg atcggcaagt
    24301 tagctggaga attccctcca agaccggatg tctggacaac atccccttct ttgatatccg
    24361 tatcaccagt taattgggtc accactaagg catggagctt ttcatcatag tttttaagca
    24421 aaccaaacgc ttcgccatta gccgaagata cccgtactgg aaaatgattg gagctttcat
    24481 tagaggatga cagtaattcg attttagacg aagccgtatt gacctcgatc actcggccaa
    24541 tcaatccttt ttgcgacatg actgccatat ttgcttcgat accgtcttta gaacccttgt
    24601 ctacgatcag catgtcctgc caactgtcag gcgaacgagt aatgacattt gccgttactt
    24661 tttcgtaact agtcagcgtc tgattcaact caagttcttt tttcaacgct tcgatttctc
    24721 tctcgtaatt cttgttttgc tgtgaaacgt catcatagct atcgattttt tcttttagcc
    24781 gctcattttc ggcataagtt gaaaaaagat tatggacaga atctactcca tttcgtaccc
    24841 accgtactgg ggcagagatt gttttatcaa ccattgcaac actgtcatta acgatggatt
    24901 ggaagaaatt gggctttcct tcattcgctc gctgcgcagc ggtcacactt agtatcgtca
    24961 ccacgatgat aacaataacc aaggtaataa taatattttt attaggattg aacttcttca
    25021 caaagacacc tcgaattaat tagactcttg tgttcaattt tatcactaaa tgccgtgaaa
    25081 caaaaggtaa gttgctcctc ttaagctttt ttttagcaaa taatagattc tgtcattttt
    25141 agcctgaaag acaaattttt ttatttgttt atggatcaat ctttgctttg aataactgca
    25201 atcataccat ctgaaaaaga aaattctgcg gtatctgaaa gaaattcgtt acttgcataa
    25261 gatgtcggat attctacttc tttattttcc aatacatact tgctgccttt taatgtaaga
    25321 ttcgagacgg gagtcaagca gcaataagct aaatacttca tatctggtat ctgtcttact
    25381 atatgctctc caggcaaata ataagacaaa taattttgac aatctctgat aataagctga
    25441 tgggcaaagg gtttgaagcg aggttccata cctaaccaga gattggctaa aagatgatcc
    25501 aatcttccgc ccgtagctcc aatcaaagtg acttccgctt gcgggtaacg ttcaaatgtt
    25561 tttaagatac ctaactgtgt atctgtatcg tctttttctg caggggaacg ggtatactct
    25621 ttggcttttg caaatacttc cttctgctct tc
//
LOCUS       DADGKS010000034        25460 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.034, whole genome shotgun sequence.
ACCESSION   DADGKS010000034 DADGKS010000000
VERSION     DADGKS010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.034"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            133..3660
                     /locus_tag="JXV47_001557"
     CDS             133..3660
                     /locus_tag="JXV47_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAX1487608.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="JXV47_001558"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="JXV47_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HAX1487609.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="JXV47_001559"
     CDS             7448..7789
                     /locus_tag="JXV47_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1487610.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="JXV47_001560"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="JXV47_001560"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HAX1487611.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /locus_tag="JXV47_001561"
     CDS             9146..11566
                     /locus_tag="JXV47_001561"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HAX1487612.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="JXV47_001562"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="JXV47_001562"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HAX1487613.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13000..13737
                     /locus_tag="JXV47_001563"
     CDS             13000..13737
                     /locus_tag="JXV47_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAX1487614.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13751..14566
                     /locus_tag="JXV47_001564"
     CDS             13751..14566
                     /locus_tag="JXV47_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAX1487615.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14579..15226
                     /locus_tag="JXV47_001565"
     CDS             14579..15226
                     /locus_tag="JXV47_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAX1487616.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15242..15898
                     /locus_tag="JXV47_001566"
     CDS             15242..15898
                     /locus_tag="JXV47_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAX1487617.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16060..16881
                     /gene="racE"
                     /locus_tag="JXV47_001567"
     CDS             16060..16881
                     /gene="racE"
                     /locus_tag="JXV47_001567"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HAX1487618.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16884..18239
                     /gene="rph"
                     /locus_tag="JXV47_001568"
     CDS             16884..18239
                     /gene="rph"
                     /locus_tag="JXV47_001568"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HAX1487619.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18240..18758
                     /locus_tag="JXV47_001569"
     CDS             18240..18758
                     /locus_tag="JXV47_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAX1487620.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18865..19365
                     /locus_tag="JXV47_001570"
     CDS             18865..19365
                     /locus_tag="JXV47_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAX1487621.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19645..20565)
                     /locus_tag="JXV47_001571"
     CDS             complement(19645..20565)
                     /locus_tag="JXV47_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HAX1487622.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20730..21743
                     /locus_tag="JXV47_001572"
     CDS             20730..21743
                     /locus_tag="JXV47_001572"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HAX1487623.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="JXV47_001573"
     CDS             complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="JXV47_001573"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HAX1487624.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22828..23268
                     /gene="fabZ"
                     /locus_tag="JXV47_001574"
     CDS             22828..23268
                     /gene="fabZ"
                     /locus_tag="JXV47_001574"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAX1487625.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23383..24144)
                     /locus_tag="JXV47_001575"
     CDS             complement(23383..24144)
                     /locus_tag="JXV47_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAX1487626.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24333..25427
                     /locus_tag="JXV47_001576"
     CDS             24333..25427
                     /locus_tag="JXV47_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAX1487627.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         8441 a         4420 c         5378 g         7221 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg agcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttacaaatt actaaactat cagatataat gtattttatt atacatcttt
    12961 aaaagaaatc ttactaaata ataatgggag tgtaattcta tggcaatgat taaatttgat
    13021 cacgtggata aatattatgg caagttccac gcattaaaaa atatcaatct cgaattcgag
    13081 aaaggagaag ttgtcgttgt cattggtcct tctggttcag gaaagagcac gatgcttcgc
    13141 tgtatcaatg gattagagac gatctcttca ggtaagctgc tgattaatga tactgacttg
    13201 catgataaaa agacaaaact gacagaagtc cgaaaaaaca tcggcatggt tttccaacat
    13261 ttcaatttgt acccaaataa aactgttctg gaaaacatca aattagcacc aatcaaagtg
    13321 ttgaagcaag accaggcaac tgcagtcaaa aacgcggaga aatttttgaa aactgtcaat
    13381 atgttagata agaaagattc ttatccttcc atgttatccg ggggacaaca gcaacgggtg
    13441 gcaatcgcca gaggtttagc gatgaatcct gagatgctgc tgtttgatga acctacttct
    13501 gctttggatc cggaaatgat tggtgatgta ttagacgtta tgaaaaaatt ggctcatgac
    13561 ggtatgtcaa tgattgtcgt gacacatgaa atgggctttg ccaaagaagt ggcggatcgt
    13621 gttatcttca tggctgatgg agaagtattg gaagacagca gaaatgtgag agactttttc
    13681 gaaaatccaa atgaagtccg agcacagcaa tttatcagta aagttatcaa tcattgatag
    13741 gaggaaaaag atgcgcaggt taaaaaaaat acgcctgatt ttccttttag gcattgcttt
    13801 tcttgcacta gccggatgta aaggaaatgg gttggcaaat gaagatattt tagagcgaag
    13861 caaatctacc aatgaaatca tctggggtgt caagtatgat actcgattat ttggaatgat
    13921 ggatattgag agcagaactg tacaaggatt tgatgtagat attgcaaaag caatcactaa
    13981 aaagatcctt ggtgacaatg gaaaaacaga atttgttgaa gtcacttcta aaactcggat
    14041 tccattattg aaaaacggaa atatcgatgc aattattgca acgatgacga tcacagatga
    14101 acgaaaaaaa caggttgact tttcagatgt ctatttcgat gctggccaag ctttgttggt
    14161 aaagaaagga agccaaatca aaagtgtaga tgatttgaat gcttctacaa cggttctagc
    14221 agtcaaaggt tctacatcgg ctgcgaatat ccgacagcat gcaccagatg caaaaatttt
    14281 agaattagaa aactatgcag aagcatttac tgctttacaa tctggtcagg gagacgcgat
    14341 gactacggat aatgcgattt tgttagggat tgcagatgaa aatccagagt atgagttagt
    14401 tggtggaacg tttactaatg agccttacgg gattgcgatc aacaaagggc aagaaaactt
    14461 cttgaaagct gttaaccaag cgctagagga aatgcatgca gatggcacat acgataaaat
    14521 ctatcaaaaa tggtttccaa atgaaactga aggaaaagta gagtaagggg gagaggcaat
    14581 gagcgaattg atacaaactt atggaccaat ctttgtcgac gggttcaaga tcacattgtt
    14641 ttcgagtgtc ttagcacttg tgtttagttt gattatcgga acgttaatgg caatcttcca
    14701 attatcaaag aataaagtag tgagcgcctt agcaaaggca tatgtagaat tttttagaaa
    14761 cattccatta ttaatcatcg tgatgttttt ttatgttgtc gtaccgattt attggtttaa
    14821 tctagatgga ttccaagcag gtacgattgg attaacgatc tatacatctg cttttattgc
    14881 tgaaacagta cgttcaggga ttcaaaccgt accaaaaggt caaacagaag caggactatc
    14941 ttctggtttt acctattcag aaatcatgcg ttatattgtt ttaccgcaag cattcaaaat
    15001 cgttatcccg ccattaggca accaatttat caacctcgta aaaaactcat ctattttagc
    15061 aatcgtagct ggtttagatt tgatgtatca aggagacttg atcgctagtg aaacattcaa
    15121 taccttcgat acgtatatca tcgttgggtt attttactta gttatcacgc taccgttatc
    15181 ttacttaatg gtttatcttg agaaaaaatg ggcggttcgt tcatagaagg aggggaaata
    15241 catggatttt agcggcgctt tttcatggat gaatatccgt tttttattgg aaggattaaa
    15301 ggttactgtt gaagtttcat tgttttcgat catttttagt ttcttgatcg gtggtctgac
    15361 aggtgtgatt cgttttgcga atatcccttt cttttccaaa atccttggtg tagtgattga
    15421 tattatacgg aatcttccat tattattgat cattttcttc acttactttg ccttacctca
    15481 aatcggcatt cagatgaaca tcttctggtc cgctgtcgca gcattaacga tttttgagtc
    15541 agctatgttg tcggaaattt tccgagctgg actcaatgct gttccaaaag gacagatgga
    15601 agcaggatta tcaacgggac tgacttatgt agaatcgatg cgaacgatcg tgttaccgca
    15661 agcatttaaa tcaatgatcc cggcaattgt gagccaattg atttcactga tcaaagatac
    15721 ttcattagca gtaatcattt ctttacctga actttctcat caggcacgta ttatttatgg
    15781 acagaacacc aattatgtgc ttccgatgtt catcatcatg acacttatgt acttcgtggt
    15841 atgttacgcg ctttctctgc tttccggtta cttggaaaag agacggtaca gttattaata
    15901 gatgattctt ttagcggttg tggcaaacta aagtcacaac cgcttttcct ctttccattc
    15961 gaaaaaaaga gatttcgatt gttttaagca agtaagagca cttgaaaatt cacgctaaaa
    16021 agtacacaat agggaggata gaatttattg aaaaaaagga tgatacgatt gacagataat
    16081 cgccctatcg gatttattga ttcaggtgtc ggcggcttga ctgtagtaaa agaagccctg
    16141 aaacaattac cgaatgaaaa tattttattt gtaggagaca cagcacgctg cccatatggc
    16201 cctagacccg cggaacaggt aatccagtat acttgggaaa tgacggatta tctggtggag
    16261 caaggaatca agatgctggt gatcgcctgc aataccgcaa ctgcggtggc tttagaagaa
    16321 atcaaagctg ctctttctat tccagtcatc ggtgtgatcc ttcccggtac tagagcggca
    16381 gtaaaaaaaa cacaaaataa acaagttggc attatcggta cgattggtac ggtaaaaagt
    16441 caagcttatg aaaaagcact gaaagagaaa gtaccagaat tgactgtgac aagtcttgct
    16501 tgtcccaaat ttgtttcagt tgtcgaaagt aatgaatacc attcatcggt ggcgaaaaaa
    16561 attgtggcag aaacattagc tcctttaacc actaaaaaaa tcgatacatt gattttggga
    16621 tgcacccatt atccattatt acgccccatc attcaaaatg taatgggaga aaatgttcaa
    16681 ctgatcgatt ctggagcaga aacagtaggt gaagtatcta tgctgttaga ttatttcaat
    16741 ttgagcaatt caccgcaaaa tggtcggaca ttatgccagt tttatacaac tggctctgcc
    16801 aaacttttcg aggaaatagc tgaagactgg cttggaatcg gacacttaaa tgtagaacat
    16861 atcgaattgg gaggaaaata aggatgcgtc atgacgggag aaaagcccaa gagcttcgca
    16921 aactggagct tcaaacaaat gttttcaaat atccagaagg atcggtagtg atccgttttg
    16981 gtgatacaac agttatttgt tctgcaacaa tagaaaattc tgttccccct tttttgagag
    17041 aaacaggaac aggatgggtg acagcagaat atagtatgct gcctcgagca acgagtacga
    17101 gaaatcgtag agaaagcagc aaagggaaac tttctggtag aacaatggaa atccagcgtc
    17161 ttattggtcg ttccttgcgt gcagtagtag acttggaaaa attaggagaa cgtagtatca
    17221 tcgtagactg cgatgtgatc caagcggatg gcggtactag aacagcaagt atcactgggg
    17281 catttgtggc attgaaatta gccattgaaa aacttttaag agaaaaagaa ttgtcagaag
    17341 atccaataaa agaacatctt gctgcagtta gcgtaggaat cttaccagat gggacttgcg
    17401 tcacagattt ggattaccaa gaagattccg cagcacttgt agacatgaat cttgtaatga
    17461 cagaatctgg aaaattcgtg gagattcaag gaactggaga agaagcaacg tttgatggtg
    17521 aacagttgaa tgaaatgctc ttttttggaa aaaacgcgat tgaagatttg atcaaagagc
    17581 aaaaacatgc tttgctaaca gagtttgctc aaaatgatga gcggatagaa gaaacaaaaa
    17641 caatcatcat tgcgacaaga aatccaggaa aagcagaaga gtttcgaaat atgttcaaag
    17701 aagcgggata tcatgtaaaa acattacttg actatcctga attgccagat gtggaagaaa
    17761 ctggcagcac atttgaagaa aatgcccgat taaaagcaga aacgattgca caattgcttg
    17821 atcagccagt cttagcagat gattcaggtt tgaaagtgga tgctttaggc ggtatgccag
    17881 gaatctattc tgcacgtttt gcaggggaac aaaaaagtga tgcggggaat aacgccaaat
    17941 tattatatga attgacagat gtgccggatg aaaaaagaac agcacaattc cattgtacgt
    18001 tagtattcgc ggcacccaaa aaagacagcc ttgtagtaga agcggaatgg cccggtcgag
    18061 tagcccgtat accatctggc gaaaatggct ttgggtatga tcctttattt atcccagaag
    18121 gtaagaaaca aacagcagca gaattatcga gcgaagaaaa aaacaagatc agtcatcggg
    18181 ctcaagcaat gaaaaaattg agtgccgagt ggaaacaatg gctggaagga gagagataga
    18241 tgcggtattt agtagtaagt gataatcatg gagacagaga tatcctcgtt gacttagtag
    18301 atcgttatcg ttctgaagtg gatatctttt tccattgtgg tgattcggaa ttagaagctt
    18361 ctgacccatt atgggataca ttccaagtgg ttcaaggtaa ttgtgattat ggaccaggat
    18421 tcgaacagaa aaaagtgatc caaactggtc aggatacagt attcatgact cacggtcatt
    18481 tatcgaatgt ccgatttggt ttgacacagt tagcaatcga agctcgagct gcaactgccg
    18541 atatggtgtt ttttggtcat acccatcaaa taggctgtga gatggatcag aaaatcctgt
    18601 ttttgaatcc tggtagcatt tctcagccta gaggcccgat ccaaatccca tcatatgctc
    18661 ttatcgaaag tttagatgac caaatttctg ttcaatacta taaccgtgcc catcaggcag
    18721 ttgaagagtt ggccttttct ttttcgagag agcgctgaat aaaaaaactc taatttttaa
    18781 taaaaataag ctttatttta tgaattttgc atccggtttc ggtaaaatag tagtgttgaa
    18841 tgaaatagaa atggaggcca tcagatgatt ggacctatag taagagaaat gctgctggaa
    18901 aatcaggaaa cgtttttgat tcctgcagaa aatgtggcaa atgttatgta tcatcatcca
    18961 ttgtcccatg gtttacttgt gttatcgaag gtcggttatt ccaaaattcc tgtattagga
    19021 aaagatgatc actttgtagg actagtaagt ttatcagatg tggtcaataa aatgattgac
    19081 ttgcaaacaa tcagcatgga cccgttagaa ggactaacgg ttgctgatgt gacagaaaca
    19141 gatgttccga caattgatga aaattgggaa ctagaagaag tactccattt gttagtcgat
    19201 tcgccttttt taccggttgt cacagaagat cggattttca aaggaatcat tacaagaaaa
    19261 gagctgctta aagccgtaaa cttcatggtg catgaattag aacgtcgtaa tatattgtct
    19321 ccgaaaatcg aagaattaaa agaacaaatc gatatcgtga gctaaagaac gagaaactaa
    19381 aagataatca aaaaataagt agaaaaaaca gcgtaccagt tttgacttta tcttgaaaaa
    19441 gaggctggga caaaagcgtt taactccaag aaataagaag gaattcacga aaattgcttt
    19501 tcaaattttt gtgaatttca gcttatttcc gaaggagttg cttctgcttc cgccgtttat
    19561 acgtgtttag agcgtgggac aaaagtgttc tttacttttg tcccacgctc tttttagtga
    19621 gattcgttgc atcgtttgtc caaattattt tccgacagca attggactgt tcggaatcgt
    19681 gaaaccagaa gctgtcaatt ctttgacata ggagctcaag aactcttctt ttaaggcata
    19741 ttgttttccg ttcaatgcgt agcagaccgt acgaatcgca aaattgctgt ttccaagatc
    19801 cactaatcca aagatagaag gttcagtttg gagctcttct tggtattttt cagctaatgt
    19861 acgatttact cgatcaatga tctcatagat tttgtcatat ccttcttcag gaacaatccg
    19921 aatatctaaa agtacttgca tatttgcacg agagagattg ctgatcgtgg tgatgtttcg
    19981 attcgggatg aaatggacag taccatccgt tgctttcagc tgaagggtac ggataccaac
    20041 agatacgacg gttccttcaa tcgttaagtt tgctagcttg atgtagtccc caacatccat
    20101 ctgttgttcc atgataataa aaaatccggt aataacatca ctcatgaacc cttgggcacc
    20161 aagaccgatt gccacacctg caattccggc accagccaaa agtgatccga tcggcacacc
    20221 gatagcagat aaaattgcat agataaaaaa gaaaccaagg gtataatgaa aaatagtatt
    20281 taaaagacta tgtaaagtct ttaagcggct ctcgtttaga atggcttttt tagaatactg
    20341 attaaaagac ttatcaatca gatattttcc cacacggtga agaatccaaa aaaggacgat
    20401 caaaaaaatc agatataaac ttttttggat aaaggcagcc aaaatggcgt cccaatcaat
    20461 cccgtcccaa aaccgctgaa acgcatttac tttgctgaca gcttgatctg tcaatgtctc
    20521 gccagaagag tctgtcgtac cggcagttgc taataatgaa aacataaaat cctcttttct
    20581 aaaatttgat tctttctgta ttgtaccaag aagttttcaa aaaaggaaat agcaaaaata
    20641 actataatga aggaaaaaag ctgaaaataa aatgacaaat aatatggata atgataaaat
    20701 gtggagaaaa taacgaaggt ggtaagtata tgcaaatcga ttggaacaat ctaggttttt
    20761 cttatatcaa aactccttgg cgttttattg ccaaatggaa agacggacaa tgggaagaag
    20821 gagaattgac agaagataat tacctgacga ttcatgaagg ctctccagcg cttcattatg
    20881 gtcagcaatg ttttgaaggt ctaaaagctt atcgtcgaaa agacggcaag gtcaatctct
    20941 ttcgacctga acaaaatagt cgacggatga atcaaagtgc tagacgattg ctgatgccaa
    21001 tggtccctga aaagatgttc gttgatgctg tcaagcaagt ggtaaaagca aatgaagatt
    21061 ttgtgccgcc ctatggaaca ggcgctacat tatacttgcg ccctttactg attggggtcg
    21121 gtgaaaacat tggtgtccat ccagctccag aatatttatt tgtcgtcttc tgtacgccag
    21181 taggagcgta tttcaaaggt ggactaaaac caacgaattt tattgtatct gattacgatc
    21241 gtgctgctcc taaggggact ggtgcagcaa aagtcggcgg aaattacgca gcgagtttac
    21301 ttccaggaac agaagcaaaa gaactggatt actcagattg tgtttatctt gatccagcca
    21361 cacatacgaa aatcgaagaa gtaggtgcag caaatttctt tggaattaca aaagacggaa
    21421 aattcatcac tccgcaatcg ccctctatct taccaagtat cacgaaatat tccttgttgc
    21481 agttagctga agaacgacta ggactgcaag caattgaagg agatattttc attgatgatc
    21541 tagatcaatt tgcagaagct ggtgcatgtg gtacagcggc tgttatttct ccaatcggtg
    21601 ggatttatca caataacaat cttcatgtat tttatagtga aacggaagta ggaccagtaa
    21661 caaaacggtt gtatgatgaa ttgacaggta ttcaatttgg agacatagaa gcaccagaag
    21721 gctggattga agtcgtggaa taatttcaaa gtaatgagtt gaaaaaaacg taaaaagaaa
    21781 aaatcaggaa gagactttaa aaagtttttt cctgattttt atatgtttta ctttaaagaa
    21841 tgcaacaaaa gtttatgaaa gatggacacc tttgtcaacg tagataatat caccgatgat
    21901 tccgctggaa agtgggctga ttaagaaagc acaagcatta ccgacttctt cgatcgtcac
    21961 accttgctga tcaggcgtac gagattcaga taactggatc agtttttgat agtctttaac
    22021 acctgtgaca gctaatgttt tgattgcccc agctgagatt ccattgaccc gaattccttt
    22081 aggcgagaac tcagctgcca aataacggat agcagcttca agagaagctt tcgcaatacc
    22141 catcatgtta taattcggga ttgcgcgttc tgaacctaga taagtcatgc taacgatccc
    22201 gctgtttggt gcaagaaacg gttgtgcgta ttttgataca gcaattaaag agtagctgct
    22261 gatatcttga gctaattgat agccgtctct ggaaatatca gacacatttc cggacaattc
    22321 ttctttgttg gcgtaagcaa ctgcatggac aaggccgtgg atctccccag catattcacc
    22381 gatggcattc attgcttttt cgatgctttc gtcgctagaa acatcacatt ctacagtgaa
    22441 tgcttcttcg ccgaccaatt tgactaatga ttttttcatt cgttcatttt ggtaagtata
    22501 gataatttct gccccttgtt tcaacattgc ttcagcacaa ccccaagcaa tgcttttttt
    22561 gttagcgacg cccataatga cgattttttt tccttctaga aatgacataa tgactctcct
    22621 ttgtttctga taaaaatttg atagtcgtaa aaaaatagag aataatagct aaaataactt
    22681 cttgatttct taattattag tcaaaatgtt ttgattgtca aactattttt tcttaaatta
    22741 aaaaaagatt gctaaatatt taggaatatg atactttgat agtcaaagta atgaaaatgg
    22801 caattgcctg aaagaaggag tttaattatg tcttacgtat tatctgctac tgaagtaatg
    22861 gaattgattc ctaatcgtta tcctatttgt tatattgatt atgtagatac tttagaacca
    22921 ggaaaaaaga tcgttgcgac aaaaaatgta acaatcaatg aagatttttt ccaaggtcac
    22981 tttcctgaca atccagtgat gccgggtgcg ttgattctag aaacactggc acaagcaggt
    23041 tcgatactta tcctaaaatc agaagagttt ctaggaaaaa gagcttatat cggtgggatc
    23101 aataaggcca aattccgtca aaaagttgtt ccaggagatg tgctgaaatg tcattttgaa
    23161 atcaccaaaa tgaagggatc agtcggtaca gcgttatctg cagcatatgt agatgataaa
    23221 aaagtctgtg agtgcgagtt cacgttcatc gtcaaccaaa atgcttgact ataaaacctg
    23281 atatagcaaa acaaaaggaa gcttacttgc tttttatgta aaaagaagac gcctgaatcc
    23341 tagcatacgt tgtcatctat gcaggattca gacgttattt ttttattttt gttttgcttc
    23401 ttgcagtata ttgattttat cgatttttac ttcttctttt ggtttgtctg aactatctgt
    23461 ttcgatattt gcaatagcat ccacgacatc cattccttca atcacttggc cgaagacagt
    23521 ataatggcca tctagtgaag gataaccgcc gtttttataa gcgtcgatga ttgcttgagg
    23581 atagtcgtct tttaaaagac catcatgcat atcatctgta ttttgaacga taaagaactg
    23641 gctgccgtta ctgttaggat cttgtgagcg agccatagat aacgcacctc ttatattata
    23701 aaggtggttg ttgatctctg tttcaaatcc ttctccccaa atgctttccc ctccagtgcc
    23761 atcgccttta ggatcgccac cttggatcat gaaatctttg atgacgcgat ggaaagtcag
    23821 tccgttgtag taaccgtctt ttgcatgtgt cataaagttt tcaaccgctt ttggtgcgtg
    23881 ttcgggaaat aatttgattt tgattgtgcc tttattcgtc accatttcga ccagatcttc
    23941 attttcggcg acatctttcg tcaattgtgg taattccaat gcgttcaaat cgacgctact
    24001 ggcagtcgtg ctttccgcag tagatgtact ttttgaactt tctgtagacg aactagaaga
    24061 agtcgtgttg tttgcagaac aaccagcagc aaacagcaat gctgctgcta aactaatact
    24121 taaaataact ttatttttct tcataactgt tcctttccaa tttactattt tgttatcttt
    24181 aatgataaca aaatagaggg aaaataccta cttaaattat tggaatttat catttatttt
    24241 aaaagaaaaa gaaaaggtgt agaccattta ctttgtgttt gctataatgt aagtggatac
    24301 aaaaacgaaa agatgcagga ggaaatggta atatgggaaa attaggaatc tcgatttatc
    24361 cagaacggtc aacatttgaa aaggacaaag cgtacttgga tttagctcat aagtatgggt
    24421 ataaacgggt ttttaccagt ttgctgcaga tcaatgatga taaagaaaaa gttctttcag
    24481 aatttaaaga agtagttgat tacgcgaata gcctaggcat ggaagtaatg gttgatatca
    24541 atccagcgtt atttgaacag ttggagattt cttacgatga cttatctttt ttccataaga
    24601 tgggtgccta cggggtccgc ttagatatcg gattcacagg agcagaagaa gcaaaaatga
    24661 cgcgcaatcc ttttggtatc aaaatcgaga tcaatatgag ttcgggcacg aattacgttg
    24721 acaacatcat gagttattcg ccaaacacgg ataatttatt aggttctcat aatttttatc
    24781 ctcatcgata ctctggttta ggatacgaac actttgtttt ttgttcagaa aaattcagaa
    24841 aatataattt gaatacgatg gcattcgtca attcgcaatc tgctgagttt ggcccttggc
    24901 ctacgcaaga tggcttgtgc acgctggaag accaccgaga tcttgaaatt gcgacacaag
    24961 tgaagcattt aatccttaca ggattgattg atgatatttc tattggaaat gcgtacgcaa
    25021 gtgaagaaga attgaaagaa atggcagaag catttaacgc ggattatcca acattgaaag
    25081 tagatacgga agaaggtatt acagaaaacg aacgaatctg cttgtttgat aaccttcata
    25141 gttatcgagg ggatcgctca gaatatatcc ttcgttcaac gatgactcgt gtatactaca
    25201 aagataaaga tttcccgcct cataatacgc gagatatgca tcatggggat gtactgattg
    25261 acaatgaagg gtacggtcaa tacaaaggag aaacacaaat cgccttgaag gatatgaaaa
    25321 acgacggacg tgtcaatgtt gtaggaagaa tctccgatga cgaattattc ctccttgact
    25381 ttttgaaacc atggtcaagc tttaaattaa ttgaaaataa aaaatagata attagttatt
    25441 gcagaaataa tccgctagaa
//
LOCUS       DADGKS010000035        25123 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.035, whole genome shotgun sequence.
ACCESSION   DADGKS010000035 DADGKS010000000
VERSION     DADGKS010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25123
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.035"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            6..245
                     /locus_tag="JXV47_001577"
     CDS             6..245
                     /locus_tag="JXV47_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487628.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKEVFKALSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            312..521
                     /locus_tag="JXV47_001578"
     CDS             312..521
                     /locus_tag="JXV47_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487629.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKTMKQKHLKRLSVAQYINDMQLT
                     GKEKACLLGSMKNFEQLRRTYRIHF"
     gene            581..1252
                     /locus_tag="JXV47_001579"
     CDS             581..1252
                     /locus_tag="JXV47_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAX1487630.1"
                     /translation="MKKWLFGFLGVTLIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVLAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            1305..3281
                     /locus_tag="JXV47_001580"
     CDS             1305..3281
                     /locus_tag="JXV47_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAX1487631.1"
                     /translation="MAINRYVKKAGMLIGMLGIIAGCFQGYRAYAEDITQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PTEDSDLTNAKVDEIVKDVEDKGSNSEYVKNATNKITSAVDENGEITFADQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDNTGSGFLKDIHLYPKNIVSKLSFELTK
                     FGDDGTAQSKQTPLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDKEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLVDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGEYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQTYVLISCLLLGAGALSAVVYFKKKA"
     gene            3296..4048
                     /locus_tag="JXV47_001581"
     CDS             3296..4048
                     /locus_tag="JXV47_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAX1487632.1"
                     /translation="MIIRKPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVAKIELGDPVGILTILSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLESNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            4064..4819
                     /locus_tag="JXV47_001582"
     CDS             4064..4819
                     /locus_tag="JXV47_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487633.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADRQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGHEKQEGVNG
                     AKFSVYDVSDILQKMDVKDLTTDQIESQLKNRVKKLSSDQLKLVSNEETKTIDQQTGV
                     FEFSVEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSEAS
                     QPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            4832..5092
                     /locus_tag="JXV47_001583"
     CDS             4832..5092
                     /locus_tag="JXV47_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487634.1"
                     /translation="MKLIKLLLFNFSCLTAVFLYCGLLFSKLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            5089..7179
                     /locus_tag="JXV47_001584"
     CDS             5089..7179
                     /locus_tag="JXV47_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAX1487635.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKSTDLKGEYAHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVNYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEGSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLSNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTISAVSLLL
                     LVLATFSYAVLRYI"
     gene            7206..7670
                     /locus_tag="JXV47_001585"
     CDS             7206..7670
                     /locus_tag="JXV47_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487636.1"
                     /translation="MKKLIIVVTSLIAMIVILVGCSNEKNKQTNQDNGVLKSGTMWKE
                     EVGGLVYNLKIIDETTWEYSESVWHPDPVQITVKRQKDYKGLERYKIVDSAGVREFIN
                     KSDSLFIVVPYEKNGVKKIIFLGSSKDEKRTKEKLIHDGSQSNKYKLQKTSE"
     gene            7667..7909
                     /locus_tag="JXV47_001586"
     CDS             7667..7909
                     /locus_tag="JXV47_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487637.1"
                     /translation="MIASLFICPEGGITVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            7927..8229
                     /locus_tag="JXV47_001587"
     CDS             7927..8229
                     /locus_tag="JXV47_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487638.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAAAA
                     VASIVIGGLFFLFGRRGAENGKMHVGYVLMGVGVILAAASIVVSLFGLFGQTPQGL"
     gene            8299..10362
                     /locus_tag="JXV47_001588"
     CDS             8299..10362
                     /locus_tag="JXV47_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487639.1"
                     /translation="MYFTIAGNTKTDKELIKKATKEVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGKVLEHESRSSVKLTLTLHDTEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVNQGSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEESTWTEGDSQEYIEPLISEEVEKNEIEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVA
                     KINNFTQTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMEKYEKIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLELKKREQD
                     LAEQQMAIEKQRLNQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPTPSVAAVQTPM
                     NNQTNLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTTSIKEE
                     AQEQARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKAKEGSSDSTVQSNTSESSE
                     SNEVK"
     gene            10362..12974
                     /locus_tag="JXV47_001589"
     CDS             10362..12974
                     /locus_tag="JXV47_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HAX1487640.1"
                     /translation="MRVRETTKRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     KKIFYSGLVYLPLEYLVTRVPEVFNRLEIVKGSLQGINLFQLQEMPQVFHFDSAGFWN
                     PFTPTTSLGTRLAISTVCVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSVGFPKYLDLKLHESLLNQRVVVEFYHKGK
                     KFHEERVKVGYKGFCEINFDCHLVAGDQVCLKYDHQGKEYVAWYEFSQRVLKDEEGNI
                     VYRKKRGETHLPELEKEAVLTLDEEKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSLENETAKKLLIQFYEEQAADRLQEYVEKLIKNKEISEMI
                     GKRLLLESEKVVKE"
     gene            12971..15502
                     /locus_tag="JXV47_001590"
     CDS             12971..15502
                     /locus_tag="JXV47_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487641.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDANPKTVTKVLQDYGNYLQYQDV
                     FSWIWNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNALFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKSFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PKQAKEMADKDKSGLSDLQKDRLRALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYR
                     RYSSKPGIILAGESSLAVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGF
                     GHRKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEEKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTTEKENQEGIVIPSVKDHQEALHSNENSIEEKNSIEERNSEEGKNGQLPK
                     TDPEQYRYKPNSDLENEKRISDLSKVNQEDKAENEGQLPKTDPEQYRYRSVNSENEKR
                     ISDLPKRNQEVQTDEDSIVLPNDNGIEVGTEKSTKIGLPKAQNLPMKDSRLNQFKEND
                     QSFVHQSTAGTVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREAAPKPIQN
                     VHTGYKPANVAFTAPTKINVTRETKNRNNALKEQLLRDIKQDIKP"
     gene            15552..15884
                     /locus_tag="JXV47_001591"
     CDS             15552..15884
                     /locus_tag="JXV47_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487642.1"
                     /translation="MDKYINMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            15885..16478
                     /locus_tag="JXV47_001592"
     CDS             15885..16478
                     /locus_tag="JXV47_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487643.1"
                     /translation="MRVKGQNSVERKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            16641..18665
                     /locus_tag="JXV47_001593"
     CDS             16641..18665
                     /locus_tag="JXV47_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAX1487644.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTETQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNAINPDFIETVNYVTNFQ
                     REMRKVEAMTVLATQSPQEMVPENMSSDNFSKLKKVFEFSSTKIFMRMDESILRHIEG
                     LVGKSMTNSELESIPQQNQGDAVINFGSKETIRVHFSPNKRQLKLFDGGK"
     gene            18665..19864
                     /locus_tag="JXV47_001594"
     CDS             18665..19864
                     /locus_tag="JXV47_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAX1487645.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWVFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYKLL
                     PSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKFPN
                     SKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSAYYKNCMSII
                     NTNKLMEYDEFAIKHWREGGGTGGTITGSWGNPFPGSSLDKNSFSGGQLFGKNPGGEF
                     RPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVYQE
                     FANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDPLP
                     FLNSSKK"
     gene            19880..20524
                     /locus_tag="JXV47_001595"
     CDS             19880..20524
                     /locus_tag="JXV47_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487646.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQETNTYKIEEVAK
                     NASDKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPADDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            20535..21341
                     /locus_tag="JXV47_001596"
     CDS             20535..21341
                     /locus_tag="JXV47_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487647.1"
                     /translation="MSKKKGARQRFKKRKSYLRWLGIFMILGFLILASPIYTHKKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIKAKVIKVSDDYFVVKLAHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQMKDQEEIIQKLQEKIDRMTKEKI"
     gene            21363..21593
                     /locus_tag="JXV47_001597"
     CDS             21363..21593
                     /locus_tag="JXV47_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487648.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
     gene            22107..22415
                     /locus_tag="JXV47_001598"
     CDS             22107..22415
                     /locus_tag="JXV47_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487649.1"
                     /translation="MEVRIRNVDEKIVREIDRRCDELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQDKFDQLLNQLIDKFSFVQSHNTKVLEEYICQNNQIIELLIEQSRGGEV
                     "
     gene            22417..22839
                     /locus_tag="JXV47_001599"
     CDS             22417..22839
                     /locus_tag="JXV47_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487650.1"
                     /translation="MAKVIDKHIYFYETHIDVLDEIIATHAEVKNYSEAVRFLCMNYD
                     SEVEKKVNSNQAKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKTISESVTTKSEVFDPTRFLKR"
     gene            22859..24448
                     /locus_tag="JXV47_001600"
     CDS             22859..24448
                     /locus_tag="JXV47_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487651.1"
                     /translation="MSKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEKERRTPEE
                     EQELRLIKNALEDFYIPEGETFSESKTGKEFSETSNEAQSLMKHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKVLTHSEQKEYQRLNQAIKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQTFQRGQQKGSIIYQDVVSHDHSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKKNTRKPYTEIENGVSYIVPKG
                     KRRQATLDEMKTNYVHELERFSYEKNRMGMEKRNLLTRKSDLRNTLTKVVKEPVRYDR
                     HAMSLLTEVYKNLPKKRSEWHYGDENRTKLSPYTREKLDELTQYVLTKEPGYQEYIQI
                     SKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQDSQIKPLIERMDQ
                     MQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEEK
                     YHASKAYEEQQRRIQMEQERQ"
     gene            24460..24795
                     /locus_tag="JXV47_001601"
     CDS             24460..24795
                     /locus_tag="JXV47_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487652.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLINEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            24936..>25123
                     /locus_tag="JXV47_001602"
     CDS             24936..>25123
                     /locus_tag="JXV47_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487653.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYP"
BASE COUNT         9386 a         3904 c         5155 g         6678 t
ORIGIN      
        1 agtagatggc gcgaccagtt ttagaggcga tggatatgga tactttgaca aaaggaaggt
       61 atgtacagct gttagctcgt ggttattcac ctaaagaagt attcaaagcc ttatctaaag
      121 gaacagatat ggaaaaagaa agattgcgaa aagaattcga ttattggaga acccataatg
      181 gaatcaagga tttgaaacca gcacggccag taattaaacg aaagaaaaag ataacccaag
      241 actgaagtgt agagcgtatg tgatcatagg cttttttatt tttgcaaaaa acaaggaagg
      301 taggaaaact catgaattat gaagaaatcg aaaacagaaa aaaagtgtcg aaagaaatgg
      361 aagaaaagtt actaaaaacg atgaagcaaa aacaccttaa aagattatct gtcgcgcaat
      421 atatcaatga tatgcagtta acaggaaaag agaaagcttg tttgttaggt tcaatgaaaa
      481 actttgaaca gttgagacga acttatagaa ttcattttta aaactttttc tatggaaatg
      541 agaaaaagtt tttttgtttt gtctgaaagg aggcagatgg atgaaaaaat ggttatttgg
      601 ttttttagga gtcactttaa tcgtcttttg cagtgtgttt ggctatgtta gctaccaaaa
      661 acatgaagga gaggtgttta agcaaaatat agaaaaaaag atgcccgtag atcaaatcaa
      721 tgcacatgca aagagttata aggaggatgc aacgaacgtc aataatgata tgtctttggg
      781 gcaaatgttg tccatacaaa aagaagcaat cgaaatgggc gtcaataaac aagtacttgc
      841 acaaattcag attcctgcac ttggtttagc attgccaatt tttaaagggg caaatcaata
      901 cactttgagt cttggagcgg ctacttattt ttatgaagat gccgaaatgg gcaaaggaaa
      961 ctatgtccta gcaggtcata acatggaaat gccaggtgtt ttattttctg atattcagaa
     1021 gttgtcatta ggggaggtga tggacttagt tagtaacgat ggcgtctatc gttacaaggt
     1081 aacgcgtaaa tttatcgtac ctgagtactt taaattaatc gatggcgttc ctgaagagaa
     1141 ctctttcttg tctttgccaa agaaaggaga gaaaccctta ttaacgttgt ttacttgtgt
     1201 ctatacgtca caaggaaaag aaagatacgt ggtacaggga gagctacaat aacaaggttt
     1261 taatcaacgc gagtcgttga aatatgaaat gaggagagta aaaaatggca ataaatcggt
     1321 atgtaaaaaa agctggaatg cttattggaa tgttaggaat cattgcaggc tgctttcagg
     1381 gatatcgagc atatgcagaa gatatcacgc aaaaaacgcc accagaaaag gtcaatatca
     1441 cggttcataa attaatgtac gatcaaggaa cgcaattgaa tgttgatatt gacgggatca
     1501 aaaacgatgg ttatacgcac gatcaatatc ctacaggtgt aacgaaatac aacaaggcag
     1561 attatggtga tgttgagttt acgttaggaa atattacgga tcaagtatta ccgactgaag
     1621 attctgatct aaccaacgcg aaagtggacg aaatcgttaa agatgtagaa gacaagggat
     1681 ctaacagtga gtacgtcaag aatgcaacaa acaaaattac ttcagctgta gatgaaaatg
     1741 gtgagattac ttttgctgat caaccagcct atgtcaattc caaagggaat gtatatgtgg
     1801 tttatgaaag taaatccgct gctggattag tcacacaaaa agcaaaacca atggttgtga
     1861 ttgcgccaat gactgataat acaggttcag gttttttaaa agacattcac ttatatccta
     1921 aaaatattgt ttctaagttg agttttgaat taacgaaatt tggtgacgat ggcacagctc
     1981 aaagcaaaca aacaccttta aaaggggcaa aatttgagtt atacaagggc gaacctggaa
     2041 aaggaacaaa attaggagat cttgtatcgg atgatcaagg aaagctgact gctactgatt
     2101 tgacgttagg aaaatactat tttgtggaag ttccttcaga agttgtagtg ggatcagata
     2161 aagaaccaac agcagatcaa tatttattag gcgcagacgc tcgcaacgat gcgcacaata
     2221 aattaacctt tgaaattacg aatgatggcg tgacaagtga cttaaaagct tcatacgtaa
     2281 actataaagc accagtgatc gataaaacag taacaaatgg aacaggacaa gaacattctt
     2341 tccaaattgg tgacgcagta aattatcaag gaacaattca tatcccaaca gacattgcag
     2401 gcggagcaga cggtatcaca gtaaacggag tgaaaagcga aacttctcct tacagtgtat
     2461 ttaaatgggg ggatacagca ggacaaggac tttcttatgt cgctgctaaa gcaaatatca
     2521 aagtaacaaa taaagatgga tctgtggtat taaaagaaaa tacagattat aaaatccaaa
     2581 attcagaaaa tggctttgtg atcgatttta tcgtgaataa tggccaagta agtgatactg
     2641 tagcaagttt acacggacaa gatcttcaaa tgacttataa catgtatgta aatgacagcg
     2701 cagctgttgc caatccatta acaaatagcg tggatttcgt ttataacaac aatccattta
     2761 atcaggaaga acaccacgaa aaaacgaaag ctgacgttgt gacttatggt gcaaaattct
     2821 taaaagtcga tagcggacta tttggaacag gaatcaaagc aacaccgctt gaaggcgcag
     2881 aatttgctgc taaaaacgca gaaggaaaat attatggtgg attagttgat acggataaag
     2941 acggtgtcaa agaagcagta tgggtagacg atgtagcaaa tgcagcgatc ctaaaatcag
     3001 ataaagaagg tcactttgaa atcactggtt taactgaagg tgaatattca ctggaagaaa
     3061 caaaagcgcc tgaaaactat caaaaattaa cgaaagagat ctctttcaaa gtagacaaag
     3121 attcatacaa agaagaaaac cgaatcacga tcaaaaacaa tcaaaaagct tccgtaccaa
     3181 tgaccggtag caacggtttt caaacgtatg tattaatctc ttgcttgttg ctaggagcag
     3241 gggcactttc tgcagttgtt tactttaaga agaaagccta gaaggatcaa aaccaatgat
     3301 tatcaggaag cctaagaaaa agcgaatcat gggtaaatgg atcattgctt tctggttact
     3361 ttcagctgta ggtgtcttac ttttgatgcc tgctgaagcg agcgtggcga aataccaaca
     3421 aaatcagcag attgccgcaa tcgatcgaac aggaacggca gcagaaacgg attcttcttt
     3481 ggatgttgct aagattgagt taggcgatcc tgttggtatt cttacaattc taagtatttc
     3541 tttaaaacta ccaatttatg acggaacgtc cgacaaaatt ttagaaaatg gtgtaggtat
     3601 tacggaagga actggtgata ttacaggagg aaacggtaaa aatcctttaa tcgcaggtca
     3661 tagtggactt tataaagata atctttttga tgatttacct tcagtaaaaa agggagaaaa
     3721 gttttatatc aaagttgatg gtgagcagca cgcttatcaa atcgatcgga ttgaggaagt
     3781 gcaaaaagac gaactacaaa gaaactttgt cacttactta gaatcaaatc ccaatgaaga
     3841 tcgagtaacg ctaatgacat gtacgcctaa ggggatcaac acacaccgtt ttctagtgta
     3901 tgggaagcga gtaaccttta caaaatcaga attaaaagat gaagaaaata agaaacaaaa
     3961 attatcttgg aaatggcttt taggaagtac tgtttttctt tcagtcatga tcattggttc
     4021 gctatttgtt tataaaaaga aaaaataaag gagggtaacc aacatgagaa atagaaaatg
     4081 gctatttgtt tgtgcagccg ctcttttttc tttcactgcc tacacacagt tgacgtttgc
     4141 agacagacaa gaaagcacgg atagcacaga acaaacaatc caaacgtcag atagcagcac
     4201 gattcaaagc agcgatgaaa ccgtcgattc gtcaacagtt gattcttcag aagaacctaa
     4261 aattgctgaa gacgatcaaa tagtcaaaca gaccattcac gttcaaaaga ttatttcttc
     4321 agaacaatta gacaaccagg ggcatgaaaa acaagaagga gtaaatggcg cgaagttttc
     4381 tgtttatgat gtatcggaca ttttacaaaa gatggatgtt aaggatctca ctactgacca
     4441 aattgaatcc caattaaaaa atcgagtgaa aaaactatcc agtgatcaat tgaagctagt
     4501 ttctaatgaa gaaacaaaga caattgatca acaaacaggt gtctttgaat tctcggtaga
     4561 agtacaggca aatcagaaac aagcttatta tattgtcaat gaatcaagtc ctgaaaacat
     4621 ttctaatagc gaggatattt tgctattaac acctgtttct gataaaaacg gtgaattctt
     4681 aaaggatgtg tggatctatc ctaaatcaga agcttcgcaa cctaaagaag aagtaaaaaa
     4741 aatcgtttct actggcgtaa agaaaaactt ctttgagaat tgttgggatt ttgttactca
     4801 cttgttttct agagattaag gaagaaataa aatgaaactg atcaaattat tattattcaa
     4861 tttttcttgt ttaaccgcag tctttttgta ctgcggttta ttattttcta aactatctat
     4921 tttgccaagc taccaactat acctaatgag gattttaaac ataccagctg cttccatgcc
     4981 gctagatatt atggaaaagc tcattaggaa tccattattt actacgatca atttgatcgt
     5041 tattgtcgga atttcactag tcatttataa aaaagagggg atgaagggat gaattttaaa
     5101 cactcgtgga caagacggtt aaaatatgtt tttcccataa tgatgatgtt aggtacattg
     5161 tttgggttaa aaacagccaa tgtctttgct gaaaaagtta ttgtcgatcc gtcaaatcca
     5221 atccagaacg taaagaataa ttttattatt ccaaaagatg ttcctaatgc aaaaacaaat
     5281 attactgtaa acggagcgtc aaaagtttac aaatatcatg ttgatgccaa caaaggtggt
     5341 tttacagacg actacgtagg attagtggag ggaaacaaaa atatacgcta tccttctttc
     5401 caaaaagaat acggtgaaac aaaccttgtt ttagaaggcg taacaaccaa caccaaagtc
     5461 aatattgact atggaaaaat cggtacgtat aacgggaaaa aagtcaatat caagctagtt
     5521 ctatctaata ttcacttata ctcggatacg ttgccgtgga atctactaga taacaactat
     5581 acaaaaactc attttcgaga cgatggctat aaaaatacga atggtgcaat gagtaaatct
     5641 aaaaaaagaa cagtactttg gatctcagac aatcttttct caggaattgt ttaccattca
     5701 acacaaatga atgtgcagct agtagccaca tatgaggacg gtagccccgt tcaattttca
     5761 ggagatacat ttatcagttt taactctttg aaccctgcag gaggaaaaag cacggatctt
     5821 aaaggagaat atgcccacta tgacaaaatg aatacgacag attggtatgt cagaaaagat
     5881 acggttcttt cagaatttaa atctttctac aacaatctga acgtggtagg tggccaccca
     5941 ggaggaagct ctaagctgac acaagcggat aatgatttca ataatttgca tgataaatta
     6001 ggagatccga agtttggtca aggtactgtg tcctttaaaa tatctgaagc aaatccgacg
     6061 tttgtgattg gttcttctaa tgttcaaacc tggtttactt tatcttctgc gacaatcttt
     6121 agtgttgttc ctgatcaacc tgaaaaaaca ggggttgata aaaatggaaa taacgtgaac
     6181 gataaaatgt tgcaagtagg agacacgatt caatatcgaa tcaaacagaa ggtgaatcga
     6241 ttaggagtgg atttactagc ggtttacgat cgatttgagt taatcgataa tttaccaaaa
     6301 gaagtaaatt acgtcgatgc acacgttgaa agtggtacaa ataaaaaatt cgatgtatct
     6361 ggtgaagtga cctatgacaa aacaaaacac caggtaaaat atgcagcgaa agctgataca
     6421 ttaaaaaatc gaatgaagta taacggcgaa acttacgaat tagtgatcaa tgtaaaagtc
     6481 aatgaattgg ccaatcaaaa tagtgtagcc aaaaatcagg gaacgtcgat cattaataaa
     6541 gtagaaaagg atacaaatat cattaccgtt tatttcccta aaattccagt gaaagaagta
     6601 caacaaaatg gaaaagatgt aaacggacga aatgacggta agaagggtac gccgacagct
     6661 cctttaaacg caggatctga agtacaatat ctagtcacac aaaaatggca cacaaaaggc
     6721 gtagacgctg cgtcagatca ctacaaacaa tttagtattc aagatccaat tgaagctcgt
     6781 ttgacatata aagaaggttc tgcgcaagta atagataaga gtaaaggaaa agatattact
     6841 tctgaaggca cactaaccta tgatagcaat tcaagaacgc tgaagtggga agcttccgct
     6901 gacttcttaa gtaacaatct tttagatgga cgagaaattc agctgatatt tacagctaaa
     6961 actccattac aatcagaaaa aaatattgat aaccaagccg tagtagcagt agataatgtt
     7021 tctaataaaa caaatgttgt gacaattggg gttgatccta acttgccaca ggtcattgtt
     7081 cctaaaacag gttctacaca tttagtaacg atttcagcgg tcagcttact attacttgtg
     7141 ttagcaactt ttagttatgc ggttctgaga tacatttaaa ataaaaaaac gaaagaatga
     7201 ataaaatgaa aaagttaata atagtagtta cttccttgat tgccatgatt gttattttag
     7261 tcggatgtag taatgaaaaa aataaacaaa ctaatcaaga taatggcgta ttgaaatcag
     7321 gaactatgtg gaaagaagaa gtaggtggtc ttgtttataa tttgaaaatt atagacgaga
     7381 ctacctggga atactctgag agtgtatggc atccagatcc tgtacaaata acagtcaaga
     7441 ggcaaaaaga ctataaaggt ttagaaagat acaaaatagt agattcagct ggtgttaggg
     7501 aatttataaa caaatctgat tctttattta ttgttgttcc ctatgagaag aatggcgtaa
     7561 aaaaaataat ttttcttgga tctagcaagg atgaaaagcg aacgaaagag aaattgattc
     7621 acgatggatc acaatccaat aaatataagt tacaaaagac tagcgagtga ttgctagtct
     7681 ttttatttgt cctgaaggag gaatcacagt ggcaaaagct aaaacgccat ttgaaaaagc
     7741 cgcgtctaaa atcttagaac gccgcggtgt atctgaaaca cagtggaaac aagaagtcct
     7801 tgaaaaagca caatttgacc tattacgggg aaaagacaag gacttagaag gatatatcta
     7861 tcaacgtgaa cgtgaaaagc ttgttttcga tgaaattatt aaacactaaa aggagcgaac
     7921 aattttatgt ttgaatcaat tacaatgaat tttttaacac aaccgaaagt agtagctgcg
     7981 gttgatattt ttagagcatt acaaactgcc gcaactagtt taaaaaacaa tctgatgatt
     8041 tttgctgctg ctgcggccgt tgcttccatt gttattgggg gtcttttctt cctatttgga
     8101 cgaagaggag ctgaaaatgg gaagatgcac gtaggctatg tattgatggg ggtaggagtt
     8161 attttagcag cagcttctat tgtggtttcg ttatttggat tgtttggaca aacacctcaa
     8221 ggattataag aaagtaaaaa agtaggagta agaagtagtc gatacttttt actccttttt
     8281 tatgaaagga gaatactcat gtactttacg attgcaggca ataccaaaac agataaagag
     8341 ttaataaaaa aagcaacgaa ggaagtagga aagcgtactt cttttttacc gaaaacaatt
     8401 aaatattctg tcattgaaac ggaagaacag ctacatgtgt tagggaaagt actggaacac
     8461 gaaagtcgat cttctgttaa gttgactctc acgttacatg acacagaagg aaaaatagag
     8521 aaagctggta cagaatacgt ttttggccca ctggattatc aaatttcaga aggtttctat
     8581 cctacattga tggatttaat ccgccttgat gtgtttaaag aaacggatga aactatgagt
     8641 gtggaagagt cttatcgaaa cgaaaaactt ttacaagttt tagaagaaga gttagagagc
     8701 gaccaaagaa aagtgaatca agggagtgaa gtcgaagtaa atgaagaagt accatgggaa
     8761 cgaccaatat ttccaaagaa ggagtcaaaa gaaaaagaga cagtctatgt tgacgaacaa
     8821 gctgatattc cgactcagaa atcgatattt gaggaagaga acgatgtgat gggtcaattg
     8881 gaggtagatc cctttgaaga aacaatggag gatgaagaga cggccgaagt agaagttgat
     8941 ccagttgaag cgaatgaaga gtcaacatgg actgaagggg attctcagga atatattgaa
     9001 ccacttatca gtgaagaagt agaaaaaaac gaaatagaga tacaaaaggc aactgtattt
     9061 gattatattt tggatcaata tccgccagag catgaatgga tgaaagaaaa aaacaaatta
     9121 tttttaaatg agctttattc gaaatatcaa ttaccccaaa cctatcaagc atttttagag
     9181 agtaaagaag aattaatctc acagggtaaa ggcacacttt tagaacagtt agagtctgtc
     9241 caatcaacaa attggcatga gcttgcacaa gaagatttat tagccacctt tgaagaacgt
     9301 caacaagaaa cagatcaaga aattaatgag tatgcgacgg aacagtcgtc taattgggag
     9361 aaagcaaaag aggaactaaa taaagaagaa cagcgagtga ttgaagaaga agtacaaaaa
     9421 attaaagagc gatacgaaaa gaaacgcgac aatgcgtatt ccttgtgtgt agcaaagatc
     9481 aataatttta ctcagacgaa tcaagaagcg ttatcgaaag aaaaagaaaa cttgttaaaa
     9541 gaacgtatta aagaacgaaa agaagaattt taccgaggtt tgcgtacaga taagctaaag
     9601 attagcaaag aattaaatga acaactgaat aagctatatc aaacaacgac tgaagttctt
     9661 atggaaaaat acgaaaagat ccagcaagaa ttacaagtgc aaattccaaa atggaaaaaa
     9721 gagtatgaaa ttcaacaaca agaattgaaa gaacaagaag aaaaacaacg gcaaaaagaa
     9781 aaagagcgcg aacaattaga actaaaaaaa cgtgaacagg atcttgcgga acaacaaatg
     9841 gcaatagaaa aacaacggtt aaaccaagaa aaggaaaaag aagcagctgc tcgtaaggaa
     9901 cgtcaagaac aaatggatac attgcgacaa gctcagttaa attatctagc acaacctcaa
     9961 ccaacgcctt cagtagctgc tgttcaaacc ccaatgaaca accaaacaaa tctaactcct
    10021 tcaccacagc gttcctttaa cggatggatg gtgggatgta ttgcaagttt aagcttgctt
    10081 ctaggtggag gaacagtatt tgcttttaat catatcaatc aatcttcaca ggctgattct
    10141 gtggccacaa cgacgtcaat caaggaagaa gcccaagaac aagcaagaaa agagtatgaa
    10201 caacaattag aagaattatt gaatcgtacc aatcagtcaa caacagagtc aagcatggaa
    10261 aatagcaaag agagtgattc tagtaaggct aaagaaggat caagcgattc aactgtacaa
    10321 tcaaacactt ccgaaagttc agaatcaaat gaggtgaaat aatgcgtgtt agagaaacaa
    10381 cgaagcgaaa agacaaacga ttcaatttag aaaagaatag gtatctttct catttctatc
    10441 gctatactcc ctcaggagaa gagctaccag aaaaacatga caaacgcatt tcgaaaaaga
    10501 ttttttatag tggacttgta tacctccctt tagagtattt agtaacaaga gtaccagaag
    10561 ttttcaaccg attggaaatt gttaagggaa gcttacaagg aataaatctg tttcaattac
    10621 aggaaatgcc acaggtcttt cattttgatt cagctggttt ttggaatcca tttactccta
    10681 caactagttt gggtacacgt ttagcaattt cgacagtttg tgtggttcca gctgtactta
    10741 tgggattgaa aatggacatg tggtttcgtc ctctagcaga tggacaaaaa ggggataatc
    10801 gattaatgac cttaaaagaa atccaacaga tttatccgca aatacctgaa acaaaaacta
    10861 cttttccagg ttatggaggt attccaatca cacattacaa aaaatattgg tacattcaaa
    10921 cagatactgt taatacgtgt attgttggta cctctcgatc agggaaaggt cagattgaag
    10981 tgttagccac cattgacaat ttatctcgtg cagaaaaaca aagttcaatg gtcgttaatg
    11041 atccaaaaac agaattatat gttggtagta aagatgaact agaagctaga gggtatgatg
    11101 tatatgcctt taatatcacc gatccactgc aatcaatgag tgataatcca ttggcactca
    11161 tcgtgaaata ctggaaacga ggagacatag atactgcaac acagttaacc aatactttca
    11221 caaatacgat ttattatgat gccaacgctt cagataacaa atactttaac gaaaacgcgc
    11281 agaaagctgt caatgcgctt atttttgcgt tgttagaaca agctgatcaa acaggagatt
    11341 actccaaatt gacaccgaat aatctcgttg agcttctttc tgagattggc ggttttaatt
    11401 attatccaga tccagacaat gaattcaaac agttgaatgc cttagatgaa tttatgaatc
    11461 agttgccacc tggaaacatt gcaaaaaaac aatatggggc aacgaaaatt ggatctgata
    11521 aagcgaaggg aaatatttta tcaacggcaa tcacgggatt gaatccattt actctaacga
    11581 aaattgcaaa gatgacttct caatcaacga ttgattataa atcggttggg tttccaaaat
    11641 acttagattt gaaattacat gaaagtcttt taaatcaacg agtcgtagta gaattttatc
    11701 ataagggaaa gaaatttcat gaagaacgtg tcaaagtagg ctataaagga ttttgtgaaa
    11761 tcaattttga ttgtcattta gttgcaggtg atcaagtttg tttaaaatac gatcatcaag
    11821 gaaaagaata tgtggcttgg tatgaatttt ctcaaagagt attgaaagac gaagagggta
    11881 atatcgttta tcggaaaaaa cgaggagaaa cccatttgcc agaattagaa aaagaagccg
    11941 ttctaacatt agatgaggag aaaagtaact tattagtaga gtctattcgg atgcactata
    12001 ccgataaacc aatggctatt tttatgctta cacctgatta tgatccatct aaccatatca
    12061 ttgttagtat ttttcttagt cagttatata aagaattatc tacgcaatgt gttaagacta
    12121 aaggagataa atgtcaccgc aggattcatt ttattttaga tgaatttggg aatatgccac
    12181 caatggataa tatggaagga atcatgacgg tcacagctgg ccgaaacatg ttgtgggatc
    12241 tgtttattca atcttatcag caactttatg cgaagtatgg agaacaaaac gcagcgatta
    12301 tcaaagaaaa ttgtcagaca catatttata ttatgtcgac agatgataat accatcgaag
    12361 aattttctaa aaaagtgggg aataagacgg ttgaacaaga gaacagtacc atcaattcat
    12421 taggtatgaa tactcatatc aatcgcaatg ttgattcaga tcgtatctta actcctgaaa
    12481 gaatttctac ttttttagaa ggtgaaacga ttgtactcgc tcctttaaaa cgacaagatt
    12541 tgaaaggtca taaaatacgg ccgtatccta tttttaatca tggggaaacg aatcttcctt
    12601 atgcttatca atatattgaa gatttcaatc catcgtggga tatcaatgat atagacatac
    12661 attgtacaca tgcggacttg gatcttaagg ctttacaaat tgattatgat tatttcctac
    12721 cagatgaata tgctagaaat ctctatcatg gactgcatga tcaattagaa gaaaaaaacg
    12781 aagaaaatat gttttataaa atcgttcaat ctcttgagaa tgagacggct aaaaaattgt
    12841 taattcaatt ttacgaagaa caagcagcag atcgacttca agaatatgtt gaaaagttga
    12901 tcaaaaataa agaaatttct gaaatgattg ggaaacggtt gttattggaa tctgaaaagg
    12961 tggtgaaaga atgatcattg gaggaatttt ttctggcata gccgactggt ggtcaggctt
    13021 attcggagaa ggggatgcaa accccaaaac cgtaacgaaa gtcttacaag attatggtaa
    13081 ttatctgcag tatcaagatg tatttagttg gatttggaac acttttctgt ggggattgat
    13141 taaaggatta tataatctca atactttact agaaaaaacc atttatcaaa gctttgattt
    13201 aaaagactta ttgaacgccg ctggggtaaa tgcactattt caaagtttga ttagtaaggt
    13261 attggctctt ttttgtgtcg tcacattaat ttatttaggc ttgaaatttt ttatgagtaa
    13321 acacccacca aaagtcaaaa atatcttggt taatttattt atggccatga tcttgatttt
    13381 tggtgggagt tctttaatcg atgaagggtt aaatatcagt aaaagctttt acggagacgt
    13441 cactgcagca aataaagcag ataaaacggg ttcacctgct tttcaaatta ttcaaaataa
    13501 tgtgatcgat gtcagtacat tactagcaac tgacccgaat aaagtagaat ccctgccaac
    13561 agacaaaaga aatgctttaa cagcgaaaaa ttttaaaaca gcgaatatca atgggattat
    13621 tactcctaaa caagctaaag aaatggcgga taaagataag agtggtttat cagatttaca
    13681 aaaggatcgg ttaagagcgt tacaataccg attggaacta gatgataatg ggaaagaaat
    13741 tcctgttcaa attagtgacg aaggcttagc aaaatatgtc tatacttcag ggtatcgtcg
    13801 atacagtagt aaaccaggta ttatcttagc tggtgaatct tctttggcgg tggcctattt
    13861 atttatccta tttacgatcg ttacttgcat tattgagctg gtatttaaaa aattctattt
    13921 agtgattgcc gcgtcaacgg actttgagac aggccaacgg atgaaaagtg cgatagaaga
    13981 tatttctcaa tccttcttgt tattggcgtt tacgatttta gaattacgaa tctatacatt
    14041 aatgctttca ggtatcggtg atttgcatgc ggcaggaaag atcaatggat tcttgtatgt
    14101 tgttgcttta attgtgctaa ctattgcgct attcaaaggc tctcaatcgg ttacgaagat
    14161 tttcggtgtt gatacgagtc tgaaaaacgg cagtaattct cttcttagca tgtttgcctt
    14221 aggaaatatt gcgaaaaatg tgggtagcgg agctaaaaac cttgcaagtg ctggtaagag
    14281 tggtttaagc catttaaatg atattcgtaa aaatggattt ggccatcgaa aagatgttac
    14341 ccctgataac ggggaagaac aatcagacga taaagctaca actgtaccta atagtaagaa
    14401 aacagtttcc gaaatgttcg ggaaagcgaa aaatggtgtt tctaaagccg cagaaggtct
    14461 tggttacgtc aatgaacgtg ggttaaaagg aacagctgaa gatcttacag aaaaagccaa
    14521 agacacctta gaagagaaat tagacggcac gagagctaaa gaattggctg aagctgtgaa
    14581 gaatccatcc gaagcactag aaaaacaaaa agaaaaagct tcagaagtca aagaaggact
    14641 aaaagatgcg tatggtgaag gacaagttaa tgcagcagta aaagctaata caacaaccga
    14701 aaaagaaaat caagaaggta tagtgattcc ttcagtcaaa gatcaccaag aagcgttgca
    14761 ctctaatgaa aattcgattg aagagaaaaa ttccatagaa gaaagaaatt cagaagaagg
    14821 aaaaaatgga cagttaccaa aaactgatcc agaacaatat cgctataaac ctaacagtga
    14881 ccttgaaaat gagaagcgaa tttcagattt atcaaaagta aatcaagaag acaaagcaga
    14941 aaatgaggga cagttaccaa aaactgatcc agaacaatat cggtatagat ctgttaactc
    15001 cgaaaatgaa aaacgcattt cagatttacc aaaacgaaat caagaagtac aaacggatga
    15061 ggattccatc gttctgccaa atgataatgg aatcgaagtt ggaactgaaa aatcaacgaa
    15121 aattggttta cctaaggcac aaaatttacc aatgaaagat agtcgtttga atcaattcaa
    15181 ggagaatgat caaagctttg ttcaccaatc aactgcaggt actgttcaaa tgaaaccaag
    15241 tcgtttgcct gaaaatggaa atctgacaac tgtttcttac aatttatctg aaagtggtga
    15301 gacagggaat gcgtccgttc aaaatgttgt gacaagagaa gctgcaccaa aacctattca
    15361 aaacgttcat acaggttaca agccagcaaa tgtggcattt actgcaccaa caaaaataaa
    15421 tgtgacaaga gaaactaaaa acaggaacaa tgcattgaaa gaacaactat tgagggatat
    15481 caaacaggat atcaaaccat aaaaggccta caagttaggc cttttattta tatgaaaagg
    15541 agaaatcaat tatggataaa tatataaaca tgaaaaaccc tccaagattt agtggagaat
    15601 ggaagttttt cgcttttttc tttttagatc tattaacgct tggtggctgc tttttttggg
    15661 cgaaaatggt caataatctt gtccacttac cactcttttt tgcactcttg aattatggct
    15721 tatggattgc gatagcgtta gtgattgttt ggcgacccta taataaccca ggtcaacgac
    15781 aaatttttgc gattatcgag tctatttttt ttgcggacaa gaaccattat catgcgttag
    15841 atcctaaccg aaattatcat ggtacgtata aggaggatga ataaatgcga gtcaaaggac
    15901 aaaattcagt tgaaaggaaa tccattttgc agtttggaaa accagaagag cgctctatct
    15961 tggacttatt tccgtataaa tcctgtacag aagagggagt cttaattact agagaagatc
    16021 attttcaacg ttattatcgt gtagtttcta cagacgtgga aggattaaat gaacaagaga
    16081 aactagaacg aatgaatcag ttgaccaccg tcatgcgtac gtatgtgcca acaattaagt
    16141 tagttagttt gaccacagag acggatctaa cggaacaaat cgtgcaaaag cggcaattat
    16201 tagataaaaa tcgtatggaa cagtccttag gaagaaatct acaacgatta aaaaaatatg
    16261 aaaagaaatt agtcgaagaa atccaggaat tgaaacgagc agaacaagaa cgtcctgact
    16321 taagcttctt tttcgtcatt gaaggaaaga caatcaagga tttacaaacc agaaaccgtc
    16381 agttaatgcg atctagtggc attttagggt taaaaccact ctacaaaaaa gaattgatca
    16441 agattctgta tcgaatgaac aatatgaatg atgagtagga atggagaaga gagaatgaaa
    16501 tatccgttga tatggttaga aaaagatgtt ccgaaggaag agaccactag aaaatttcct
    16561 cacactttaa gcctgggtaa gttgggaaaa gggcaatctt ttaaccaagt aaagaatcaa
    16621 acaagaagag gtgactgtac atgttagaag caattaaaac agctttttca ccacaaaatg
    16681 atcaaaaagt acttgatcca ttaaagcaac taggaaatcg ggaaatagaa attttaaaat
    16741 ccaaagggta tgatttagat tttttaaaac aagtgatgcc acaaggtggg ttaaattttg
    16801 atgaagaata tgtgacgtat ggtaatggtt attcacgatg tgtgacagtt tatcactaca
    16861 caaaaaatcc tacgcttttt tggttggcca atctcatgaa caatcctcat acagtggcca
    16921 cactcgatgt tagcacagat gaaaagcaaa aagtgattga tcaaatcaat cgtgccttag
    16981 atgaattaaa tgatcgatca gataatgaac gaaaagcgac tgaccgaaat aaaagcgcag
    17041 aagaatacct ggaactagcg gaatatgctc gtaaattgac ttctaatggg gaaatttcta
    17101 agcaagtcaa agtgagagta catgtttacg gaaacacgat tcaagaagta gatgaacgag
    17161 cgcaggaact gatcgaaaat ctaaaaggga tggattatcg tgcggtgact tatctgcata
    17221 aaaccaaacg agattggcaa tcgatgttta ccatgttcga tgaacaagct gaatggttcg
    17281 gaaatatcaa agggcaatca ctaccatcgt taaacattgg cggaggtttc ccgttccacc
    17341 accaaacgct aaaagatcca ggagggacac aatatgggga aaccatgaca ggcggcccat
    17401 ttgtctggaa tgcgacgtat aaaaatagtg tacggttgtc tactaatacc ttgcttctag
    17461 gaatgatggg agctggtaaa tcgaccgttc ttaaaatgat cgcggaagcc catttagctg
    17521 caggagactt tatttggggc tttgaaaagg gaaaagactt tattcctttc ttaaaggaat
    17581 ataacggtat tatggtgcgt ttagacggat ctgacggaat gatcaatcct ttagagatat
    17641 ttgccacacg gacgtatgat gaagcatcca gtttatatga cgatggatca gtcaaagatt
    17701 tgaagatcaa tgaagcagcg tcctatcaaa cacacttaga caaagtggtc tatcaggtac
    17761 agttagtgag tcctcagcta aaaggaacga tgaaagcaga atttaagacc tacttaaatc
    17821 gtttttatga agagtatgga acagtaccac gcggctttac ttcctcaaat tcgcgttcaa
    17881 atacggagac gcaagtcaca ggtaaagatc cagaagctta tccgacgttc aaagaatttt
    17941 tagacttttt aggacaactg gaattaccag gtgcttccca agagaaaaag aatcgaaaag
    18001 aagaaatgga atccatcgta gaatccttat gtgagacgta tggcatgatt tttgatgggc
    18061 atagtacgat tcgacacctt gaccaacaac agttggtctt ttttgacatt gactctatta
    18121 caggcttaga tcgaggggta caacaatgtc aaatgtacat ggctatgacg ttgatttgga
    18181 atcaggcatt gattcaagga agaagacaac gacgtttaat taaagaaaaa caaatggaag
    18241 aacaagactt caaacgcttc ttggcgatga ttgatgagtg ccataatgcg attaatccag
    18301 attttattga aacggtaaat tatgtcacaa actttcaacg agaaatgcgt aaagtagaag
    18361 caatgactgt tttagctaca caatccccac aagaaatggt gccagaaaat atgtcttctg
    18421 ataacttctc gaaactgaag aaagtctttg aattttcttc tacgaagatc tttatgcgta
    18481 tggatgaatc tattttacgt catatagaag gattagtggg taaatcaatg acgaactcag
    18541 aattagaatc cattcctcaa caaaatcaag gagacgctgt gatcaatttt ggctcaaaag
    18601 aaaccattcg tgttcatttt agtccgaaca aacgtcaatt aaaattgttt gatggaggaa
    18661 aataatggaa aaccaaaatg aaagtttaat caaacagtat gttaagcgtc gtgcaaagcg
    18721 gcgcttattt ttgtgggtgt ttggtacttc tgcaggtttg attactatat tgatcactgt
    18781 gtttgtgacc ctttttctaa tacttgcggc aggttctatt gataattctg attcaagtag
    18841 tggtggcgaa gcttttacag gagaatattc ggaaggctta cccatttata aagaaatcaa
    18901 aggaagaggc cctttttctg atgagattgc gcaatatgct gtaggtgcag cagtgaagta
    18961 taaattatta ccaagtgtga tcctttcgca atacggttat gaatcagcgt ttggtacgtc
    19021 ggcgtccgca agaaatgatc tcaattattt tgggattacg tggtttgatg ggtgtctgtt
    19081 tcctaaagga actgcgcgtg gaattggtgg cattgaaggt ggctggtaca tgaagtttcc
    19141 caactcaaaa gctgccttct cctattacgg ctttatggta gccacacaat caaattttaa
    19201 tgcttgtgtc ggaaataaaa gccctggcgc aagcttattg atcttaggac gaggagggta
    19261 tgccgccgca ggaattactg aagacagtgc ctattataaa aattgtatgt ctattattaa
    19321 tacaaataaa ttgatggagt acgatgagtt tgcgattaaa cactggagag aaggcggcgg
    19381 aactggtggt acgattacag gaagctgggg caatccattc ccaggaagta gcttagataa
    19441 aaattcgttc agtggaggac aactttttgg gaaaaatcca ggaggagaat tccgacctaa
    19501 cgggttccat gatggactag actttggttc agtcgatcat ccaggaagtg agattcatgc
    19561 ggttcatggc ggaaaagtcg tgtacgttgg caatcctggt atttcaggtt tgggtgcgtg
    19621 tgtgatcgtg attaattacg atggcttgaa tatggtgtat caagaatttg caaatagtac
    19681 aggaaattct cgagtgaaag taggcgatca agtgaaagtt ggtcaagtaa ttgggatacg
    19741 agatacagca cacttgcatt taggatttac tcgaatggat tggcgtcaag cacaaggaca
    19801 tgcattcatt gatgatggta catggatcga tccgttacca tttttgaata gcagcaaaaa
    19861 atagatcagg agaaaaaata tggaaaataa aaccttaaaa atcgtcttaa cagctgcaat
    19921 tagcgttagt ttaatcggca atattgcgtt gttttggcag cttaaagaag aacaagagac
    19981 aaatacctat aaaattgaag aagtggctaa aaacgcgtct gataagctca aaaaaaattc
    20041 ttctgaggca caggcgaaga tcgacaagtt aaatcaaacc atcaatgaga aaaaccaaga
    20101 aatcgatcag ctgaagcaac aagatggcac aaaagcaaaa gaggaagtaa ctgaagcaca
    20161 aagaaagacg gcagaagagt tcggtcaatt ggccattgat aaatcattaa gcagaaatga
    20221 attaacggaa aaactaaaag atgtcgcaac ccaagaagtg atcgacaaat taagtcctgc
    20281 agacgatgat caccaacatg acgactacgg aagttactct tttacattag gtgacgtgca
    20341 aacttacgct caaacaagca gtgtaaaaga ggaacaaaat tttgtcgtat ttgttgatta
    20401 tacaatcggc aatcctcaat ttaaagatgt caaaccacaa aaaataaaag gtggattaac
    20461 tgtcactgaa aaacaagtag atggtcaatg gaaagtcaca gactttagtt atttcactcg
    20521 ttaggaggaa gaaaatgagt aagaaaaaag gagcaagaca acgttttaaa aaacgaaaaa
    20581 gttatcttag atggctgggg atctttatga ttctcggctt tttgattctt gctagtccga
    20641 tttacacaca taaaaaggta gacataccag atgaagtaag cacgaacgca tttttaaaca
    20701 cgaaggaact gacgatggtt tcaaaagaaa aaggagcgaa ccagcaatta gtttttgaat
    20761 ttgcgatcga cgatgaagat cagagcttat taaaagaact agctaatctt aattatcgtg
    20821 tagaagtaaa gacagctaaa ggggattatc aagcaataaa agccaaagtg atcaaggtgt
    20881 ctgatgatta ttttgtagtg aagttagcac atgtaccaga agaatatatc gccatgcgtt
    20941 taaccattat tcctgaaaaa attgatccaa aagtggatat gcaagaacca caagatctga
    21001 tttattacgt tcacgaagat aaggttaaag atcaagtgaa agatgaagat tatgaacaac
    21061 atgcgatcaa ttacaaagtg aaaggataca aaaaagaaca aaaagcagca caaaaacaaa
    21121 tggaatcctt ccaagcaacc attgatttga atgaagaatt agtgaagaag ctaaaagatc
    21181 aattgcctta tcaagtcgca gatgatcagg aaaatactga aaacaagatt aatagctacc
    21241 agcaagaaat tgaaacatcg aaaacgcaaa tgaaagatca agaagagatc attcaaaaac
    21301 ttcaagaaaa aattgatcgt atgacaaaag aaaagattta gaaggacagg tggagtgaaa
    21361 aaatgaagcg aacaaacttg gctgacaaag atactttcgc tgagcagaaa gtattgatta
    21421 aagcctatct caaagttgta aaagctaaag aaatatgtcg agaagtgaat ttatctaata
    21481 caacaatatc tgagttgaag aatggtcgaa agaatttaga tactttaaaa ttcagatcat
    21541 ttgaagctct atatgtagct gctaaaaaat attttacagc tgataacaaa taaaaaacag
    21601 gagtatttta tgtgaaaaaa gtatataaaa aatgcttatg aatcagctat atcaccttaa
    21661 ccatttgtta atgagatggg agaaaacatt aaccacgatt ctaacgcaaa catcaagcac
    21721 ataaaacatt taacactcct cctttctggc tgaagatttc aaccaaacag gaagacagcg
    21781 tatcaattat agcatacact ttttcttaaa ttcatttttc atatgacaaa atatttcctt
    21841 ctaatcgaca aagttagaag gattttttat tgtctaaata cacaaataac cttaatttat
    21901 aaagagcata aggaaacgtg ggaacacttt ttaaaaaaag tgttccaata ggctgtgcct
    21961 attacgtttc tcaaaaataa ttgtgggaac aaaatattta aaaataggat agtgaaagga
    22021 tagcaaagga tagtaaaagg atagaagcag gatagcgaaa aggataggct ccttttcgct
    22081 atccttttta aattggagga attaatatgg aagtaagaat aagaaatgta gatgagaaaa
    22141 tcgtaagaga aattgatcga agatgtgacg aactaagtaa ccgaacgggt aataaatgga
    22201 gtcgtaacga ttatttaaag ctactcgttg aaaatgattt tgatcgtcct ttgatggaat
    22261 ataaacaaga taaatttgat caattattaa atcagttaat agataaattt tcttttgttc
    22321 aaagtcataa tacaaaagta ttagaagaat atatttgtca gaataatcaa attatcgaac
    22381 ttttaattga acaaagtaga ggaggagaag tttaacatgg ccaaagttat agacaagcat
    22441 atttattttt atgaaacaca tatagatgtt ctagatgaaa ttattgcaac tcatgcagag
    22501 gttaaaaact atagtgaagc cgttcggttt ctatgtatga attatgattc agaagtggag
    22561 aaaaaagtaa attccaatca agcaaagttg aatgcaatgg gaaaagaaat ttctatttta
    22621 accgaaatgg tttcagagtt tgcggatctc catttgaaag atacagggat tttaattggt
    22681 acaaattcaa ctgtttacca agaagcaaaa gagcgtgtgg aaggcaagat aaaagcaaat
    22741 caaacgaaga aatattctcc taagataaag aaaacaataa gcgaatcagt gactacaaaa
    22801 agtgaagtat ttgatccaac aaggttctta aaacgataaa aattagaagg agaatgtgat
    22861 gagtaaatca cctgcagtca ttctcacttg tcaatttacc ttgcccaata aaaaatcttt
    22921 ttcaacatac attgattata tgacaagaga aaaagcgctg gaagaaaagg aacgacgtac
    22981 gcccgaggaa gaacaggaac tgcgtctaat caagaatgct ttagaggatt tttatattcc
    23041 tgaaggagaa actttttcgg agagtaagac gggtaaagaa ttcagcgaaa cgtcgaatga
    23101 agcgcaatcg ttgatgaaac atggaatcaa ttttgacaag ttagaagaac aagattttac
    23161 caaatatctt tcttatatga cacgtcacta tgcgttagaa caaaagaaag tactgacgca
    23221 tagtgaacaa aaagaatacc aacgcttgaa ccaagcaata aaaaaatatc aaacagagcc
    23281 acacaaaaaa gcttcaggaa atcttcctgg agttttttct atggcttcag acgaagtgaa
    23341 aggaagtgat ctgaaggaga tcaagcaaac cttccaaaga ggacaacaaa aaggctcaat
    23401 catttatcaa gatgttgtct ctcatgatca ttcgtatctt gaaaaaatag gattgtacga
    23461 tcccaaaaca gatactttag atgaagaagg tttaaaagca gctggaagaa aaatgatgga
    23521 gacattgttc gagaaagagc aactgaatga aacaggctac tggatggcaa cgattcaccg
    23581 aaataccaaa catatccata ttcattttgc agttgttgaa aaaaaaaata cgcgtaaacc
    23641 atacactgag attgaaaatg gtgtgagtta tatcgtaccg aaagggaaga gaaggcaagc
    23701 aacattagac gaaatgaaga ctaattatgt acatgagtta gaacgttttt cttatgaaaa
    23761 aaatcgaatg ggtatggaga aacgaaattt attgacacgg aaaagtgatt tgcgtaacac
    23821 cttaaccaaa gtagtgaaag agccagtacg ttatgatcga cacgcaatga gcttattaac
    23881 tgaagtatat aaaaacttac ctaaaaagcg ttcggaatgg cattacgggg atgaaaatcg
    23941 aaccaaactt tcaccataca caagagagaa actcgatgag ttaacccaat atgtgttaac
    24001 aaaagaacct ggatatcaag aatatataca gatttcaaaa gcattgaaag aagaagcaaa
    24061 aagtctttat ggggaaagca agagagaatc aaaggatgca gaaaaaaatg ctctctttga
    24121 tttaaaaaag cgcacaggaa atgccattct aacagaactg aagaaacagg atagtcaaat
    24181 aaaaccttta atagaaagga tggatcagat gcaatctatt tacaatgaac gatcctttcg
    24241 aacacttaaa cagttgccaa cgaatgaata caaatatagt tacgaagaat tcatgaagcg
    24301 caggaaacaa ttccaacaaa gagttgtcac gcaacggagt ttgcgtcaat taaatcgaac
    24361 gattaatgcc catgaagaaa aataccacgc aagtaaagca tacgaagagc aacaacgaag
    24421 aattcaaatg gaacaagaaa gacagtagga ggaatagcaa tgaaacaata tttagatcaa
    24481 tggaaagtta tagaaggatc attaagagaa gaacgaatcg aacaacttcc cgattgttta
    24541 gaaaaagagc atttgtttca gataagagaa atgttgataa acgaacagtt tgatccaaat
    24601 caatttttag tcgttgagta cccagctact ggtgtgtact gttgtaatca tgtgaagggt
    24661 gaaaaatatt ttatcattca agaatatgag ggcaagttag cgccttatta tactacttgg
    24721 gaaatgaatg aagaggggat caataacttc ccgtgtaaaa gcattgaaga gtctatttca
    24781 ctcacagaat gttagttgtt aagtgaataa aagaagtaaa agagtcctga acgtgattgt
    24841 ccaggactct tttttttcac tgaattgttt tccgccaatt cattgagtgg tgcgatttcc
    24901 gtctacatta tatcaaaaga aaggaggaag aagaaatggc ttattcaacg attggagttg
    24961 ttgttgaaaa aagcagagac aatcttgttt ttgtgacaga aattcaaaca ggcagagctt
    25021 ttgtagtcac agacaaagcg gcaaaagcat atcaaagtgg cgatatttta acgttaaatc
    25081 tgactacgaa gacgttcgtc gatgcggcag aagattatcc att
//
LOCUS       DADGKS010000036        25086 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.036, whole genome shotgun sequence.
ACCESSION   DADGKS010000036 DADGKS010000000
VERSION     DADGKS010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25086
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.036"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..1073)
                     /locus_tag="JXV47_001603"
     CDS             complement(<1..1073)
                     /locus_tag="JXV47_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HAX1487654.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETL"
     gene            complement(1087..2508)
                     /gene="arcD"
                     /locus_tag="JXV47_001604"
     CDS             complement(1087..2508)
                     /gene="arcD"
                     /locus_tag="JXV47_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HAX1487655.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(2754..3875)
                     /gene="mnmA"
                     /locus_tag="JXV47_001605"
     CDS             complement(2754..3875)
                     /gene="mnmA"
                     /locus_tag="JXV47_001605"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HAX1487656.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            4279..4878
                     /locus_tag="JXV47_001606"
     CDS             4279..4878
                     /locus_tag="JXV47_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphatase"
                     /protein_id="HAX1487657.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(5016..6302)
                     /gene="efmA"
                     /locus_tag="JXV47_001607"
     CDS             complement(5016..6302)
                     /gene="efmA"
                     /locus_tag="JXV47_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HAX1487658.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(6573..6917)
                     /locus_tag="JXV47_001608"
     CDS             complement(6573..6917)
                     /locus_tag="JXV47_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HAX1487659.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(7054..8190)
                     /locus_tag="JXV47_001609"
     CDS             complement(7054..8190)
                     /locus_tag="JXV47_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAX1487660.1"
                     /translation="MKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGRHAH
                     EKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIEHPA
                     VLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPIK
                     EIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKRDGV
                     NIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLILDTL
                     EANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNIEPS
                     HVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(8379..9353)
                     /locus_tag="JXV47_001610"
     CDS             complement(8379..9353)
                     /locus_tag="JXV47_001610"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAX1487661.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(9433..10308)
                     /locus_tag="JXV47_001611"
     CDS             complement(9433..10308)
                     /locus_tag="JXV47_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HAX1487662.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            10438..12345
                     /locus_tag="JXV47_001612"
     CDS             10438..12345
                     /locus_tag="JXV47_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HAX1487663.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(12886..16164)
                     /locus_tag="JXV47_001613"
     CDS             complement(12886..16164)
                     /locus_tag="JXV47_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HAX1487664.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(16435..16980)
                     /locus_tag="JXV47_001614"
     CDS             complement(16435..16980)
                     /locus_tag="JXV47_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAX1487665.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(16992..17684)
                     /locus_tag="JXV47_001615"
     CDS             complement(16992..17684)
                     /locus_tag="JXV47_001615"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HAX1487666.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(17703..17987)
                     /locus_tag="JXV47_001616"
     CDS             complement(17703..17987)
                     /locus_tag="JXV47_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487667.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(18000..18563)
                     /locus_tag="JXV47_001617"
     CDS             complement(18000..18563)
                     /locus_tag="JXV47_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAX1487668.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            18791..19453
                     /locus_tag="JXV47_001618"
     CDS             18791..19453
                     /locus_tag="JXV47_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     protein"
                     /protein_id="HAX1487669.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            19577..20773
                     /locus_tag="JXV47_001619"
     CDS             19577..20773
                     /locus_tag="JXV47_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HAX1487670.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(20874..22250)
                     /locus_tag="JXV47_001620"
     CDS             complement(20874..22250)
                     /locus_tag="JXV47_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAX1487671.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(22287..23153)
                     /locus_tag="JXV47_001621"
     CDS             complement(22287..23153)
                     /locus_tag="JXV47_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HAX1487672.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(23242..24267)
                     /locus_tag="JXV47_001622"
     CDS             complement(23242..24267)
                     /locus_tag="JXV47_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAX1487673.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(24285..24959)
                     /locus_tag="JXV47_001623"
     CDS             complement(24285..24959)
                     /locus_tag="JXV47_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1487674.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
BASE COUNT         7488 a         5423 c         4424 g         7751 t
ORIGIN      
        1 tccaaggttt cttttttaca acagtaacct agtcgggcat gcttcggtaa atcaaaggca
       61 cttcctggta ctaatagtac tcctgtttct tctaataaat tgatacaaaa tgtctggtca
      121 tcttcttcga tggctaattt aatgaaagaa gtagagacgt aattgggagc gacaagttca
      181 actttcggtt cattggctac ccattgtttt aaaatcacaa ggttctctgt aatgatcttt
      241 ttgtttcgcg ccaatatttt ttctttattc ttcaatgcat gtacagcaag atcatctgac
      301 aggactccgc cgcaaatcat cgtgtagtct cgatactttc gaaaaacttc tgccaactca
      361 ggtccagtag ctgtccagcc aatacgaata cctggaatgg agtaggtttt ggatagggaa
      421 ttggttgcta tacctttttc atagacatct acgatcgaca agaattcacc tttatccgtt
      481 aaaggcgcat atacttcatc tatcaataca tatgcatcta ctgtacgagc aatttctgcg
      541 attttttcta aagttttccg atctagcaat gtgcctgtag gattgtttgc actattcaaa
      601 cagatgattt ttgtttcagg tttgactaag gcttctagct gttctaaatc aaactgccaa
      661 tcttcttctt ccttcaaatg aacaaagtca acagcggcac ctaaagattt ggggatgtca
      721 tataattgct gataagtagg aagcatcgaa acaacatggt ctcctgcttc cactaacgcg
      781 tatagagcta aaagattagc accagtcgct ccattcgttt gtaagatgtt ttccggatcg
      841 acggtttgat aaagagaagc gacttcttgt ttgaaaacat ctgatccttc gatccagcca
      901 tagtccaatg gttcgttttt gcgtttttcg aaaaatttac ttacgctagt cccatctaag
      961 ccaacgagtt cgtctaatgt caatgcttcg atcgagcttt gtgcaatatc atataccgct
     1021 ttcttttccc atttatttag ccattcttct acaccgaaat ttgcgatttt catgtttctt
     1081 tcccccttat atcttgatcc agcctacagc aagcaacccg attgaaagca gtgcggccac
     1141 acaaatcagc ccaatcatta ctttttcttt tcccgtaatt tgatgtttgg tttcacgaca
     1201 agcgatccag tagaagcaaa aaccaggaag ataggcaata ctacataaaa ggacataaga
     1261 aaatcctgct aaaatgatgc ccatcaattc aaaaactaca gcaatcccac cgatcactac
     1321 ttgttttttg attccttctt ttaaagaaaa ctggacttga tagatcccga caagtagata
     1381 acaaatcaaa attgccgctg tacataaaga ataggcaaat tgataggcat aatcagtaac
     1441 taagaaagtc aataagaata gattagtcaa gattgcagta acaactaacg aataagttgg
     1501 ggcatttttt ttattcgttt ttccccaacc tttcggcaac agaccgtctc gagccatcaa
     1561 catcgttgtt tctgctggga gcatcgtcca agacaaccaa gaaccaatga tcgaaataat
     1621 caagccgata ttgatcagcg ctgctcccca atttcccacg attcctttta aaatatttgc
     1681 catagcaggt tgtgaaatag ttgctaactc ttcttgagat aagacgccgt atggcaagat
     1741 cgaagcaagg atatagataa acaataaaca aagcagacca atgatcgatg cttgctgggc
     1801 ttctgaacgt ttcttcgcgc ggttggctaa aacacttgcg ccttcgatcc ctacaaagac
     1861 ccacatcata accatcaaac aacctttaat ctgcaaccag atcgttcctt gctgccctgt
     1921 tccattcact agattatcag atacgttacc ccaaaaatca gcagtgaata tattcacttt
     1981 aaatgcgata aatacaaata ttaaaaatag gaataatggc actaatttac agatcgtcac
     2041 gattgtattg atgacgctcg ctccttcaac tccattgttt actaataaag tcagacccca
     2101 aataaaaata cttgcaaata aaatagaagg aacattttgt ccacctttga atatcgggaa
     2161 aaattctccc atggcgctca tcagcatcgt tgcaaaagca acatttccca gccacgcaga
     2221 caaccagtaa ccccaaccac tgatgaagcc acctaattta ccaaatgaag cttccgcgta
     2281 accgaaaata ccaccatcta gatctggacg cttttctcct aaatgattca gcgataatac
     2341 caaagctaaa ataccaatcc caacgattat ccatgaaagg atcgctggcc ctggagctgc
     2401 agaactagcc agatcacttg tgatcccaaa cacaccgctt ccgattgacg aactgacaac
     2461 cagagcaacc agtccccatt tgctaatacc cgtcgatttc ttttccattt ccatcaccct
     2521 cacttataaa attgaacaaa tcacttgcaa aagattccct tctattttgc aactgctctt
     2581 gcttaacaaa aagcaacttt attcatatta ttggatatta tgaacttttt acacaagtat
     2641 ttcaagtata aaatgaataa aaattaattt tattgcaaaa aaacagctat gctatccaaa
     2701 agaaaaggtg tttcttttgt tagccatagc tgttttgatt catttaatat cgcttaaacg
     2761 tattgtaaaa cttttgtttc ttgatatgcg tggtcgatca aaccaccacc cagacattcc
     2821 attccatcat aaaatacaac tgcttgtcca ggagtgattg cacgtacagg ttcgtcgaat
     2881 acgacttctg cacgattatc atccaataag cgaactgtca caggaacgtc ttgctgacga
     2941 taacggaatt tcgctgtaca cttgaattct tttggcattg gttcattcgt cgtaaagtgg
     3001 atttcacttg catccaagct tgtggcatac aatgcaggat gatggaaccc ttgccccaca
     3061 tataatgtgt ttgtcgctag atcttttcct acaacaaacc agggttcttg cgaatctcct
     3121 ccgccaccga tccctagtcc ttgacgttga ccaatcgtat aatacatcaa gccagcatgt
     3181 tgtcctttga cttcaccatc aagagtgacc atatttcctt tttttgctgg cagatagttg
     3241 ctcaaaaatt gtttgaagtt cttttcacca ataaagcaga ttcccgttga atcttttttc
     3301 ttagcagtcg caaggcctgc gcgttcagca attgcccgta cttctgattt ttccatgccg
     3361 cctagaggga acatcgtttt tgaaagctgt tcttgtgata attggctaag gaagtaagtt
     3421 tgatctttat tattgtctac tccacgaagc atgtggacca cgccgttttc atcgcgagtg
     3481 acttgcgcat aatgtccagt agctacataa tcggcgccaa gatccattgc ataatccaag
     3541 aatgctttga atttgatttc tttgttgcac atcacgtctg ggttaggtgt acgtcctgcg
     3601 cggtattcgg ctaggaaata ttcaaataca cgatcccaat attctttttc aaaattcaca
     3661 gagtaataag gaatcccgat ttgagcagct actttcgcta catccttata atcttccgtg
     3721 gccgtgcata caccgttttc gtccgtgtca tcccaatttt tcatgaatat tccgatcacg
     3781 tcgtatcctt gttcctttaa caaaagtgct gttacagatg agtcgacacc gccgctcatc
     3841 cctacgacaa cgcgtgtttt gctgttgtct gtcatgatat caccatcatt tcaattagat
     3901 tctgaaacat ctacgagttg aaggtcgcaa cttttcagta ttttacatta tacgtcatat
     3961 ttctgaaaat ttcatccctt aattatcaag tcgtaaaaat actgttctac tggacctatt
     4021 cagtacacaa acatgatagt caaccaaaaa atcactcatc ttttgagcat tcgatataaa
     4081 aaattggcat actcataaaa agggccagcc tttcggcaat aaggaataat tttataaatt
     4141 gtgaaaaact atttttcaaa attgcttctt atcgcttaaa gctgcacgtc tcatttacaa
     4201 ccttttcttt ttagatgtta tgagttgctc agataagtga ttttgtttac tctaagaaaa
     4261 aagggaggca aaagatacat gaattacttt atcagtgata tgcacttttt ccatgaacgc
     4321 ttattaggaa aaaacgactt tgctccgcgg ctctttgcaa atgtggatga aatgaaccaa
     4381 cagttgatca ctagctggaa tgcagtaata aaagaaaccg accatgttta tcatctaggc
     4441 gaccttgcta tgcatccgca atatgaaaaa gcaaatgcag aaattttgga actggtcact
     4501 caactgcaag gaacaatcca cttgatcaaa gggaaccatg acagtcgcgc ttttttccgt
     4561 tatttagaaa aaaatgatcc taggcttact gacggaagtc ccaaatttta tttttatgat
     4621 gtaggtgcca tcgttaaatt cgaccatcaa caatattact tgactcatta tccgatgttg
     4681 ctcgggccta acgacactat ccgcaatctt catggacata tccatcatta cagcgtacct
     4741 atcgagaacg atgtcaatgt aggcgtagac gcaccggaaa gagaactctt aaaggaaaaa
     4801 ctaccatttg gcactccgtt atctgagcaa caaatcaaag aaatctatga agcaaagagg
     4861 aagtacgata ggtcgtgaaa aaactgccct atatcaagta ttaaacaaat aaagataatt
     4921 actcatattt ttcatttgag taggcttatt gccacaggaa cattaggatc agaaatggag
     4981 ttgtaacaag acttctgtca caactccatt ccatactatt cgtctttttg ctcatggtgt
     5041 tcttttacca gttttttctg taattcttta tcataatttc gggcagctga cgttaaaaat
     5101 aaaacgattc cgcataataa aatcccgatt ccggaaaaca agaacatttt ttctacccct
     5161 aaacgatcag ctaatggtcc tgcaaataat aatccaattg gacctgccag gttcatcaaa
     5221 gagttgaagt tccctaagac acgacctaaa acattcgatt cataactctg ctggatcatt
     5281 gccatcagca gtgtattgaa atatggcgtt gcacaacctg ctcctgcatt caagataaga
     5341 aagtacaaga acccttgact atcgtttgga accaatccgc ttgcaccgat cgtcaggccc
     5401 ataatgatgt aggctataat aataggtttc attcggtctt tccatgttcc tataaaactg
     5461 atcagtgcac cgcctaagag cattccgact gcgtagacta cttccactgc tcccgcctgt
     5521 ccaacggaac caccaaagta atctagcgtc atcaatggat acagactgat tgctggcatg
     5581 aacaacagca tcacaaatgc accattgatc gttatgtacc ataacccttt attatccatc
     5641 aattgctgca gcccaaattt tgcatcttta aaaatagtaa gcggaacttc caatatttca
     5701 ggagaaactt ttgggatctt cacaaaaatc aataagccga caccaaaaac tgcccccaat
     5761 acatctaata aaataaggta attgacagga acgactgaaa acaaagccgc acctagagct
     5821 ggcgcaatga tgaaattcgc tgattggacc attcctaact gtccattcgt ccttgttatg
     5881 tgagaagatg gaacgattgt cggcataatc gactggatcg ttggcatttg gaatgtttgt
     5941 gcgaccgaac gcataaacaa agacacaaaa actagccaaa tcgggaagga ttctgaaatc
     6001 gttccgacta ctgctaaaat aagcgcgaaa atcgctacaa taatatccgt gacaatcaaa
     6061 agagcttttt tatcccagcg atccactagc ggtcctacaa atgggcttag taaaaccatg
     6121 ggaatcattc ctagtaaagt agcaaaactc aaaattgtcg ccgaaccggt ttctcttgtc
     6181 aaataccaga tgatcgcata ttggacgacc atactagtga ttcctgacaa aaactgtccc
     6241 gataaaaaga acaaataatt tctcttccaa ttcgttaaaa cgaccgactg ttcattttcc
     6301 ataaacatcc ctcttttctt tttcattttg tatagcgttt gcacaacaat cattatacgg
     6361 gattcttttt tcaaaaaata cctttttccc taaataacaa tcgtttcaat ttaaatttct
     6421 ttacttagaa acaataaatc agcaaaatat taaaaataac aacatgtgtt aaatttaaaa
     6481 ataaaaaaga caactaattt gcgtcgtcct tacaaagtta gtcatctaac aataggccgt
     6541 ttcaaaacta gttgtctttt tatatccaca gatcattcga ctttttcgaa taacccacgg
     6601 ctaatcatcc catccatcag aaaataaaat ttatcttggc tcattttctg ttttggatct
     6661 ttgaaaatat tgactgcttt caatccattt gctgtagtga tcgacatttt caatgtttga
     6721 atatcttttg atacagtgat ttttaatttg aatccttctt tgctttgcgg cgtggcatct
     6781 aatggtcgga tcaattgata attgcctccg tttgtttctg taaatccatt atcgcgcaat
     6841 gtatatcttt ttgcatcagg atgcaaacga tagctaattg gtgcgcccag taccgttgct
     6901 gttgtttcaa atgccatgat tttcacctcg ataaaattag tttctcttta ttataaaagt
     6961 ttatcctgat ttttactagg tttttcagtt aagttcccta aaaaatgaag gcgttctctc
     7021 agacatctgt tcatataaga atgacttcac tagttatttt ttgacagcac gaactaattg
     7081 atcaaggaaa tactggatgt cgtcttcggt atttcccaaa ccaaagctga tacggatgga
     7141 ttcttttagt atcggtgtat cttctccata cattgcttct aatacgtgtg aaggctcgat
     7201 atttcctgct gtacaagctg aaccagtaga aatagcgacc ccattaagat caagcttcat
     7261 cagtagcaaa tcatttgctt cgccaattaa gcgaagattc aacacatgag ggagtttatt
     7321 cgttaaatca ccatttactt gataagggat ttcgtttgct tctaatgtat caagaatcaa
     7381 ttgctggaat cctttatatt tgttgttacg tgcttcacgt tcttcaggtg acagcagttc
     7441 aactgctttt gccatacccc agatccctgc taaattttct gtacctgcac gccgcttttc
     7501 ttcctgctcc ccgcctaaaa gcaatgcagg gatatttact ccgtctcgtt tatataagaa
     7561 accgacgcct tttggcccat tgattttatg agcagagata cttaataaat cgattcctaa
     7621 ttcttctgga tggatcgttt ggtttccgta cgcttgtacc gcatctgtat ggaaataagc
     7681 tggatgatcc gctaaaagtt caccgatttc tttgattggc atcaaatttc cgatttcatt
     7741 gttcccgtac atcacagaga ccaagatcgt atcttctcgt aacgcttttt tgacctcttc
     7801 gatcgacaga ttcccttttt catctacagg cagatatgta acgtcaaacc cctttgtctc
     7861 taaatatttc atggtattaa gaacagcagg atgttcgata gctgtagtga ttagatgtct
     7921 gccttctttt tgacgcgaga acgctgtttc taagatagct gtattatccc cttctgttcc
     7981 cccactgtta aagatgatct cgtgaggttt tgcttgcaga ctgtctgcaa tgatttgtct
     8041 tgctgtttcc aatttttcat gcgcgtggcg accaaatcca tgtatgcttg aaggatttcc
     8101 aaacgtgtct tgcatgattg ccgtcatcgc ttcaattact tgtggatgca tgggggtagt
     8161 tgccgcatga tccagataaa tagttttcac ttcattcatc ccttccaaat tattgctagg
     8221 cacattctag cataaaatag cgaacaaacc aaagaagagc tcatttttgt ctagaggacg
     8281 tttcatgggc atagaaaaaa ggagctgtga caaaagtctt gtcgcagctc cttgaagctg
     8341 ctcacttctg tcacaacttc tttccctctt ttttttgttt attcgaattc tttttcttcc
     8401 agacggaata acggactcat cggtgtattt tcatggatgc gtttgaccgc ttcacccatt
     8461 aattctgaac atgtaacgat tgttaagttt tctggatgac gattttcttc tgtgaaaaca
     8521 gaatcagtga tacaaatatc tttgattggt gcattgtcta aaatactttt cgcatgatcg
     8581 gacaataatc catgtgacgc acaggcatat acttcttttg cgccgttttc ttttaataca
     8641 tttgctgctc gtgcaagcgt tgctcctgtg ttcaagatat catctaccat gatacatgtc
     8701 tttccttgaa catcaccgat cacataacca ccctcagttg aagcatcatc tgcatgatct
     8761 acgatggcta atgtgctgtt caaatattct gaaagactac gtgcacgctg aacaccgctg
     8821 ttttttggcg aaacaactac gatgtcatct cccgtcagac ctaattgacg gtaataatga
     8881 gcaaacaacg gcatcgtaaa taaattatct acaggaatat caaagaatcc ttgtacttga
     8941 accgtgtgca gatctaaagt cagtactcga gttgcccctg cttcttcgat caagttagcg
     9001 atcaatttcg cagtgatcgg ttcatgaggt ttcgccgtgc ggtcttgcct agcataccca
     9061 tagtaaggca atacgacatt gatcgttttc gcacttgctc gcttcattgc atcgatcatg
     9121 atcagtagtt ccatatagta atcattgaca ggtgcattcg ttgattgaac gatatacaca
     9181 tgatcccctc gaatactttc ttcgatattg atggaaatct cgccatcact aaattgcttc
     9241 acgacgcttt tacctaattc tgttccgaac actttcgcga ttttttcagc taatggacgg
     9301 ttgccattca aactaaaaat cttcaacgtg tcatcctgat acttattact catgtagtcc
     9361 tccccaaaac ttctctattc ttcgatagtt taacatattt ttccaagatt ttctgttaat
     9421 ttcagcaaat tcttaaggaa gtgaaactgt tccgttactc caactggcag gaatgacttt
     9481 atgataatcg ccccagttgt cgtgtacttt gtaataacgt tctcctgttt cagtttcaaa
     9541 ataagcgtac gctgtcaccc aatgattgcc atatgtactg ccaagtactt tcaaaatacc
     9601 aatcatcaca ggtttgcctt cacgtatacg ttttgtagct cgctgccatg aacctagaag
     9661 agttgctcgt gcacgctcat gattgccatt cttctttaaa aaactagaaa tccctgtact
     9721 aacctgaaaa ggaatcgtag gaagtcctag tggttggatc tggctacgca atgccttcgt
     9781 caaaaccaac gaatcagccg tatttttctt gcgaatctca tttggaagca tccacccctt
     9841 acgatagtct tgataatagg caaggagaac tgctgccgcg taagtaccac aaagatagcc
     9901 tgagggggta gcccatttct tatacctcaa aaaacgttct tctggcaatc ccacccagca
     9961 atttgcgagt tcctttcctg accttttttc ttcgatcaaa acgggaatat cttcttttct
    10021 gttgatccat ctagataact cgattggctc ttcattgatc agcttccatt ttttacaaga
    10081 aagaccctct tgataagtat attttgctgg agaatattct accggatgtc ctgattgatc
    10141 gataatcaca taactttgat cttcaaaaac cagagctaaa aaaagcaatt tactttttct
    10201 tgactgcagc tgctgagtgc tggctaattt tttaattttt ttatctactt tgaaatataa
    10261 aggtttatcc actacttgat tcagttggga tcgcctcctt tttttcatta taagtgaagg
    10321 attgaaaaaa acaaatcagt ttgattgttc gaattttcaa ttttttatgt tctatttgtt
    10381 aattccttca ttttgtaaga taatgggcac acgaaacaaa aaaggagcga tcgatgaatg
    10441 aacaaagaac gattgaaaca agatttctat gaagcagtca atgaagaatg gcaaaaaaca
    10501 gcaaaaatcc ctgcagataa accagctaca ggcggtttcc aagatttagt tgacgggatc
    10561 gaccaacttt tgatgggaga aacagacgat ctgcttgccc atccagaaaa agtgtcttca
    10621 gaaaaaatga aacatttcct tgcatattat caactggcaa acgattatga ccgaagaaat
    10681 gagttgcatg ctcaaccgct tcaacctata atcgaaaaag ttgaatcatt gcagtctttc
    10741 gacgaattga ataagcaatt tccagaatgg ctgttggata cattaccatt gccatttaat
    10801 ctggatgtag atgcagatat gaagaatgcg caaacgaacg ccttctttgc ttatccgcct
    10861 tctttattcc ttccagataa gacgtattat gcatcagacc atcccaacgg tgcacaacta
    10921 ataggcgttt tctttgatat ggctgttcag ttattagagc ttgccggcaa agaaaaaagt
    10981 caggcagaag caatcacgga acaagcagtg caatttgata aattgattgc tcctcatgta
    11041 aaaagtgcag aagaaaacgc agattacagc aaaatgtata atccgcaatc ttttgataca
    11101 tttattaaat acacagataa actggacttg aaaaaacttg tcacgggttt gattgggaca
    11161 actccagata aagtgatcgt aactgatcca gtgtacttcg atcatttgaa tgacatcctg
    11221 acagaagctc attttccgtt attcaaaagc tggatgatca ttaaaacagt acgttctctt
    11281 agtggttatc tatcagaaga attccgccaa gtcagcggaa tctattctcg cgtattgtct
    11341 ggaacagacg aagcaatgcc tcagaaaaaa gcagcgtatt accttgcctc tggacaattc
    11401 gatcaagtag ttggcgatta ctacggaaaa aaatattttg gcgaagctgc taaaaaagac
    11461 gtagaacaaa tggtgaaaaa aatgatcgcc gtttataaaa aacgtctaga agaaaatgac
    11521 tggcttgggg atgcaacaaa agaaaaagcc gtcataaaat taaataactt aggtatccaa
    11581 gtaggctacc ccgataagat cccagcatta ttcgaccagt tcaaaacagt acctgcagat
    11641 cagggtggta ctttgctttc aaatactctt gttttcagca aactcacatt aaaagatcgt
    11701 ttcagcaaat ggaacaaacc agtggatcgt tcagaatggg aaatgagtgc tgacacggtc
    11761 aatgcttatt atcatccatt tcggaatgtg atcgtctttc cggcagcgat ccttcaagca
    11821 ccattttaca gtctagaaca atcaagctct gctaattatg gtggaatcgg agctgttatc
    11881 gctcatgaga tttcccatgc atttgataat aacggcgctt tatttgacga atatggcaac
    11941 ttgaacaact ggtggacaga agaagatctt acacaatttc aaaacaaagc acaagcaatg
    12001 atcgaagaat tcgatggtct gccttttgct gacggaaaag taaacggaaa attaaccgtt
    12061 tcggaaaata ttgctgatgc aggcggtcta agctgtgcat tggaagcagc aaaaacggaa
    12121 tcagatcttt ctatcgagga attctttgtc aattgggcaa cgatttggcg tacaaaagca
    12181 aaaaaagaat accaacaact tttactgcaa atcgatgtcc atgcccctgc taaactccga
    12241 gcaaacgtgc aaccaaaaaa ccttgacgaa ttctatgaaa catttggtat cacggaacaa
    12301 gacgctatgt atctagcgcc agaaaaaaga gtgcgaatct ggtaagaggt tgtgccagaa
    12361 gtggtcagct tcaagaaata agaaggaatt tgggaaaatc gcttctcaaa tttttgtgac
    12421 atttcggctt atttttcgaa gaagttactt ctggaatacc atgtattaga ggttgtgaaa
    12481 aagctgctta gtttcaagta gtaagaaaaa ttttgtgaaa atggctttcc acatttttgc
    12541 ataaatttga cttactaccg agaaactggc ttttgaacac cgtttatcga gaggttgtga
    12601 aatcagcgtc ctgacctgag tattagagaa aaaaacggaa aaatagttcc tcatattttg
    12661 ccgtttgttg agctaatacc gagggtcagc tgattgaaca ccgtttagtg gagagattgt
    12721 gaaaaagctg tcctgcatca agtaataaga acagccaatc aaaagcagca aggagaacct
    12781 catctataaa aagatagaag gaagtgagac atctattggt ctcatttcct tctattttta
    12841 ctttcctcag tcaattgttt tacatcataa aaggagaaat tccacttatt tttttcgctg
    12901 tttcatgaca taaacaacta caccgattaa caaaattcct ccagctaatg ctagcaacgg
    12961 gttattaaat tctcccgttt ttgggagtcc ttgagtgcca tttttttcac tttcttttgc
    13021 tgtcctatcc ggatgagaag gttttccatt tggttttcca tttggtgatt catttcctgg
    13081 attttctctt tctggtttgt catttcccgg gggcacatcg gcagtttctc gcacagtgat
    13141 cgctttttgc tgggtaacag attctgtatg agcagaccat ttttccccat caaatatttc
    13201 cgaacgataa gtgacttcta gcgtatattc tccttttgaa ggtgctgaaa aaatagcggt
    13261 atgattagaa aattgagcac ttgactgtgt ttcaacgatt tggatctttt ctgggaaata
    13321 acgcatatct tcaaagacag gcgttccttg atttggtgtg aaagttgaca caaaaactgt
    13381 aaaaggcttc agttcaatga tatttccttc tgcattctcc gccacaccat ttgcttcttg
    13441 tataataatc ggattatttt gttcatttgg ttttgtctga tttggttctt gtacgattgc
    13501 atactctgga tattccgaag acggtgaggt ttctccgtca aaaatagcac ctacagataa
    13561 tggaagacca tccactcttt ccttttctgt ttgacgattc cccggtttaa tctgcatcag
    13621 tccatgaaca tggatacttc cattttcata gcgcgtaaca ggctgctgac cttctttcga
    13681 acatgtattt agagactcga tccaatcttt tgatatggta tgtccaagag tattttctga
    13741 ttgtttctct cgttcattcc aatagtagtt caacgagtgg tagatttgat cttcgttttg
    13801 attcaatggg cggatctgct ctctcatctc aagattctct gttcggaaag ataagatacc
    13861 agaagcatgg tagtctgtgt ttcctgctga agaggtataa agagccacat tatatgaacc
    13921 gttattaaaa cttgtactgc tattgacgat aatatctgtt ccgctattgg aatcgattcc
    13981 tttcgcaaga ttttcgaaag acaaactatt gatcaattca tgagggcccg ttaaagaaga
    14041 accgcccatt ttgaatccat taccgttacc ttctccctca attcctggta cccagccgtt
    14101 tcgataagca actgagtttt tgatgattac ttttccgatc gaacctgttt catttttagc
    14161 aaaaaggtcc caaccgtcat ctgcattatg atacgcgata caaccgtcaa atacatttcc
    14221 ttctcctatt gtcagtttgg ccgcaaatcc atcggcatct tcaaatcctg gatcggcatt
    14281 ttcaaaagat gtacagttct tgactaagtt atgcgcgggc catgcttcga aaggatcatt
    14341 tgagctaccg ctgatttgga ttcctgtatt tccattccga taagcatgaa tctcttcgat
    14401 caaattatga tttccagaaa tctgtaatcc tttttgcata gctgcactat ttgtaatgtc
    14461 aaaccctcgt aaaccccagt agtgactgaa cagtgtcatc ccatttccag ttcctttaaa
    14521 atcaagtaca ggacgcttgt tttctggatt tttctctgca atcaactgaa tcgggttttc
    14581 tcttgtcccg ttaacgcctt ttggaatcgt caatcctctt tcgaaggaat aagttccagg
    14641 cgccatgacg attgtctgcc cagcatatgc gtatctcaat gcttgtgtca gagataatgg
    14701 attttgtctg cttccgtttc ctgcatctga cccttctggt gttacataaa ctgtcgaata
    14761 tttaggttta cggtagtcca ctgtatgaag aatctctttt gtttcataac tagtcatctc
    14821 tacgtattct tctggcggat agtttttatc tggcgtaaaa ctgaaagtaa attcgttcgt
    14881 tccttccatc agttttgtct gataatcaaa ttcccgattc gcagtgatag ccaagttttt
    14941 tgcgttctta agcacctctc ctgttgcttt atttttaatt gtcaataatc cgtcagcatt
    15001 tgctctaaag gacatagtat gatcttggtt tcctgaatga ttactagagg tcacagtgta
    15061 aatcggatca atcaagcgag taggtctttc ttgcccagga ggatctgtcg caggatctga
    15121 gtaagcaact tcgattcctt ctaccttgat cgtcatattc cttgctgcag caaatcctgc
    15181 ataaataacc gattcatctg aagcgtataa tttttcccag tcatacatga tgtcagaagc
    15241 catttcttct cctgtttcag gatcgtaata atatgcctct aaaccagtat tcgttttttt
    15301 catctctacg tccagtttag taatcgagtt cgtggccgga aacagattcc catgaccgtt
    15361 tccgaatata ttataagaac ctgtttcttt ttccaagaac cctgctgaag tctctaaagg
    15421 tgttgtttcc actgagacac tcccaggagc tggcgcagct tgcggatctt cagatgatat
    15481 tcctgtgatt gcccgtgtcc ccaatccaag tcgcatcgta tatttgctgc cgctcgtgtt
    15541 gaccacttct tgtctatccg agtcccagac atattcgatc cgactgccta gtatggcaaa
    15601 tgaatttgaa taaaatgcct gcccaaacaa atgatttttt ggtactgcgt ctcttaccat
    15661 taaagcaaat ccttcttggg cattcgtata ggtccaagat tctatttcga tcgtcgcccg
    15721 catcctaaag ttgatgtctt tggggattgc ttgataataa taggtcattc catctgatcc
    15781 gcttgactgg aattttccgc cgttattcgt ggaagagagc cgcacgccgt cttctaatgg
    15841 ttcaatggca tacctactag cacttgtgct ttctccgaaa acaacccctt tccactcttc
    15901 atttgcttct tcagattgct tttttgtctt ttcattttct gattctttca tcataggatc
    15961 atttccttct tccgtatcca tatcttcact agttcttggt atttcctcca ttgttgacat
    16021 cccttcaatg ttcacgtgtg cattttcttc gttcacagac tgttgttcgt tagcagcaac
    16081 ttcaacgaca gaaattaaaa ccggggtact gagcataagg agattcatca ttagcgcact
    16141 gtattttata cgttttttta acaagtgtat tcctcccgta acaaattaga aagcgtttac
    16201 ttaaagtatt acctaattta tttttactgt caataaaaaa caaaattata ataagtgtat
    16261 tttataaaaa gaaaaaatat aacttaagtt gttgataata aagagattta ttaacgtaaa
    16321 aagaataagt ttttttaaaa taacgtataa aaaagagcat aaaacaaagt cgtttgtttt
    16381 atgctcttct tttattattt tgtgcttttt attttatcaa atcactttgt ttttttataa
    16441 aatttctgcg cctagtgtgg actcaaaatg tctcaatgcc cattcatgtc caacgggatc
    16501 gaaacttgcc acggaatctt tgaaaatatg gagtttgtat cctagattat acgcatcgac
    16561 tgctgtatgc aacacacaga tatctgtaca tacgccggtc aaataaatat ctgtgatctg
    16621 gcgttctcgc aaacggatgt ctagatctgt tccactaaaa gcggaataat gccgtttgtc
    16681 tatccaataa acattttcct cttgctcata gtcttggtat aaacttttta aagagccgta
    16741 caattcccgt ccacccgttc ctatcacatt atgcggagga aataagcggt tctccggatg
    16801 aaaggaatct tttggatcat gcgcatcaat ggcaaaaacg acaaaatcct tttgatcaat
    16861 aaacttcttt gtatgagcag tcagcttttt ttcaattact tgtcctgctg tcccagtagt
    16921 cagctttcca tcctctgcaa caaaatcata tgtgtagtca atcgagatca atgcgttcat
    16981 cttagtcctc cttatacgag atgtttgaca aattcgatca ccatttctgc tgatcgtttg
    17041 cctgcgtctt cgataaattc gtcaaagctt tgtgtcgccg agtgatctgc tgtgtcgctc
    17101 attgcacgta cgatcaaaaa tgggatattg aactgacgag ctgtttgtcc aacagcggct
    17161 ccttccattt cgcaagctaa tgcttcaggg aaattcgtta agatttcttt gattttatct
    17221 ggcgagtcga caaatgtatc acctgtaacg atcaatcctt cttttgcgtt caaattcgtt
    17281 gcttttgctg ctttaaccat ttcactgcgc aaatatgtgc ttgcttcata atatagaggc
    17341 attcctggta attgtcctgg gttgtagcca aatcctgttg catctgcatc aaaataagct
    17401 actttgtctg atataacgat gtcacctact tgtaagcctt caccgattcc gccagctgaa
    17461 cctgtattga tcaccatgtt cacgccgtat tgttggatca acagacttgt ggtaatagat
    17521 gctaagactt ttcctatacc ggaacgtacg acgatcactt cgtggttacc taatgaacct
    17581 gaaataaata aagcgcctgc gcgttcccat gataatggtt cgcttaggtt ctctctcaaa
    17641 atttttactt cttcttccat tgcgccgata ataccgattt tcatcttttt aattccttct
    17701 ttctatataa atgcgattgc taaaaaaacc acacataaca ttaggataac aataataaga
    17761 gatttcatca aaaaagagtt ccatttggtc gtcttttccc gttcgctgat ccttgttttc
    17821 gtgattggtt tattcttttt gctttcttta cgataaaagc tggcaatctt tttttcttct
    17881 tgctgataag ctgtttctgc ttttcgctgt ttttttaatg actcgcttgc ttgtgcttgt
    17941 tgtcgcttgc gaagttcgct tcgcgtaata agcggtcctt tggccataag ccgatccctc
    18001 tactttcctt tggtcaatag ttcccagtat tgaatcgcat aaatcgtctt tgcatcacaa
    18061 atcaactgat ctttcatcgc ttgttgcgcc tcttcaagag ttagatgata caactccagt
    18121 acttcgtctt catcttgtgc taaaggattc tcgaccttct ctaccccttg tgcatgataa
    18181 atatgaagga cttcatttgc aaaacctggt gaaagataca tcgaagtaag atggctcagc
    18241 gacttcgcac gatagccagt ttcttcttct aattctctag ctgctgtcat ttcgggattt
    18301 tgtccttctc ctggatcgat ttttccagct ggaatctcca aaatcacttt ttctaaaggt
    18361 tttcgaaatt gtttgacaag aagcagacga tcttgttcgt caaaagcaat gatcccgaca
    18421 ccgccaggat gaaataccag ttctctcttc gaagttcctc catctggcaa acgaacttcg
    18481 tctacagcaa catcaataat ttttccgcta tagatttctt tgcgactgat tgttttttct
    18541 tcaaattgct cattgttcag catatcttct cctgctttct ttgtaatcat aactgctttt
    18601 ttttcatttt tcaatttttc tcaaaaactc cttattagtt taccatagat aaaccttaga
    18661 ttttctctaa atatagaaaa tccttcttta gtccgatact ctttctagta gtccgtatgc
    18721 taaaataagt atgtaatcga ataacgaaaa gaattcaata ctcaacgata aatgacatgg
    18781 agggtttatt atgataaaac gaaattggcc gtggcttcta gcattggtct tgctatttct
    18841 ctttgtccga aacaatagtt tttcttttgt tctaggactt ttattgatag gtgtagtttt
    18901 agttttgtgg ggactctttg gttcgcgcag gaaaaaggga aaacaagaag aaattcctgc
    18961 actgactgac gaacttgaaa ctcactatga aaaaagcggt atgacagcga atgaaatttc
    19021 attttttcga caaacaatga atcaaacaaa aaatgagatc aatcaattgc aaatgaatat
    19081 gcagcagaca gccaaactta aagcaatcga tctccgccat gatccagtca aagcagcgaa
    19141 agctttattc aaagaattgg tgaaagaacc aaaccgactg catgaagcaa gtcagtttct
    19201 ttatacgcat ctgccgaatc tagttgattt gacaaataag tataatgaga tcaatgacca
    19261 tgagatcaaa aacaaacaga cctatgaaaa actagaagaa agcgcgcaga tcatcgacca
    19321 gctgtcagct ttaatcgcac aagattatca aaaattcgtt gctgaggatc tagatgatat
    19381 cgacgtagag atatctgttg cgaaacagag cttaaagcgt gataataaat atgaaccaga
    19441 acaaaaggat taactctttt gttcataaaa gaagactcgg aacattcaga tgatgtctgg
    19501 ctgtttcgag tactttttct aaagtagaga cattcatgta agaatcgaga acagattcaa
    19561 caaggaggaa ttttttatgg atcataaacc gactgaaaca aaagatgtta caccagttaa
    19621 cgatacactt gaagatttat tgaacaaccc gttttcaact ccaacagata cgctgaccac
    19681 ttcacaacaa gcggagattg atcagctcca agagcaacag acagctgctc gtttaattga
    19741 caaactaccg gcggaacgcc aagaacaagc taaacagcta gcagcaaaaa tcgatgctaa
    19801 tgatgcacag tctgtcatca gctacggatc ggctgcccaa gcaaaattaa gtgaattctc
    19861 acaatcgatg ttgaatcatg tgcaagcaca agatattggt cctgtaggag attccttaac
    19921 tgaactgatg tatcgtctcc aagaagccaa tcctgacgaa ctgcgtgccg gagaagggaa
    19981 catcttccag cgtgtcttcg ggaaggtcaa acaatcgatc tatgaagtga cagcaaaata
    20041 tcaaaagatt ggtgcacaaa ttgacaagat ttcagtgaaa ttagataaag aaaaagacgg
    20101 tctgctaaaa gataatctga tgttagaaca gctttaccag aaaaacaaag actactttga
    20161 tgcactgaat atttatatcg ctgctggaga attgaaaatg gaagaacttc aaacaacgat
    20221 cattccagaa gcgatgaaaa gagcagaaga aactggcgat cagatggatg ttcagattgc
    20281 caatgattac acgcaattcc tagatcgtct ggataaacgt acgcatgatc ttcgcttagc
    20341 tagacagatc acgatccagc aagcaccaca aatccgtttg atccaaaaca caaatcaggc
    20401 cttggctgaa aagatccaag catctatcgc tacagccatt ccgctgtgga aaaaccaagt
    20461 cgtgatcgca ttgaccttgc ttcgtcaaaa agatgcagta actgctcaac gccaagtctc
    20521 tgaaacaaca aacgacttat tgaagaaaaa ttcagaaatg ctgaaaatct cagccatcga
    20581 aacagcgaaa gaaaatgaac gtggaatcgt ggatatcgag acccttcaaa ccactcaaaa
    20641 tgatttgatc gaaacaatcc aagagacatt gcgtatccaa aaagaaggaa aagaaaaacg
    20701 tcgtcatgca gaagtagagc ttggacacat ggaagaagat ctgaaacaaa aactgttgga
    20761 tttaacccaa tagatcacct ttcgcttgtt actaaaacaa acgcccaaca acagtttatt
    20821 acaactgttg atgggcgttt ttcttatctt tcttctaact tctccattgg agtctatttc
    20881 tcattcatct tgctgtgtcc atagccatag ccaaaataaa tgatcagtcc aataaccatt
    20941 acgataccga acacgatcca tgtcacagtt tgcagacgaa gcatcaatac aatacaagtc
    21001 aagatggaga cgattggcaa tagcggaacg aatggcactt tgaattctcc agcttttggt
    21061 ttgccaaaca tttttctcaa cttcagtaag cctagactaa caagcatcaa ataggcgagc
    21121 gccatgatat tcgttagttc cgctaataca ttcaatggga aaaatccggc aaagaataca
    21181 gctgccacac cagcggcata agtcgctttt ttcggtgtac gatgcttttg atcgatttct
    21241 gtcataaact taggaagtaa gccatccttg ctgacagcaa acagtaaacg agcaagtgaa
    21301 tacatcatcg agatcgttac cgtcagtagc gttaaaattg cccctacagc gatcaccgcg
    21361 cccactgttc catgtcctac atacctcatt gcaaaagcca ctgggtcatt gactcctagt
    21421 tcagtatacg gaacgattcc tgtcaagatc agcgtcacga tgatgtaaag gacagtagca
    21481 atcagtatcg aaccaatgat tcctcttggc acatcttttt gcgggttttt gacttcctcg
    21541 gctgccattg caacggcatc aaatcccaag aaagcaaaaa acacaagagc tgcaccatct
    21601 agcacaccgg aaaaaccaaa aggcatgaat ggctgccagt tatcaggttt aacgaaaaat
    21661 attcctacaa tgataaacaa cgcgatgata ccaaatttga catataccat ggcattattc
    21721 aaacgtaatg ctttcttggc ttcaagcgac acgatgtaag tgacgaatat cactacgagc
    21781 accgcaatca agtcaatgta tgtaccattt tccggattgt acccgccagt taatgcttgt
    21841 ggaagttcgg cccctaaact tttcaaaaaa ccttgcatat agccagacca tccggaagca
    21901 acagaggaaa ccgctagtaa aaattccccg atcaacaacc accctgtcag ccaggcagca
    21961 aattcaccaa atacaacata cagataggca tatggcccac caatcactgg cactcgcgaa
    22021 gcaaattctg cgaaacttag tccagacaaa atgacaacga ttgcagctaa gacaaatgaa
    22081 agtgacagtg ctggaccagc attttgattg gccgcaaccc ctgtcaccac aaatattccc
    22141 gtaccgatga tcgcaccaat tccaagcatg atcaaatcag acgtttttag ttcttttttc
    22201 atctcactcg tatgattgag attgatctct ttcttacgaa acaaatccat tgaagttcct
    22261 ccccatttta ggttggaaaa cagcgattaa actgttttca tataccctaa aaggatacca
    22321 cctaaaatga ctaaaaggca accaacaata acataaatga gctctttttt cgtttttctt
    22381 tcgccaagga tgaaaatccc acctaaagta gagataatga tccccatttg tgaaagtgag
    22441 aagccaacag ctaaaccaag tgatttgact gttagaagca tgcagatgtt tcctaagccc
    22501 cataataatc cacagatcat gtttttccac acaaactgat cgactttaac tttacggaaa
    22561 gcaaagaagc ttgcgcctaa gatcattccg atactttgag gtaagataat tgacatcgca
    22621 tccaaattcg cccagttgac gatgatggta tatacaccat aaccaatcgt agagaagatc
    22681 aatgctctaa aacccttacc aaaatcaagc attttattat ctgtatctat ttttccttcg
    22741 tcatcttgtc gggcagtcaa atacgcaccg cttacaagaa gagctaaagc aataataccg
    22801 tatacataat ctttcgtttg tgtccattca tggaagaaaa cggctcccgc aatcgtattc
    22861 aaaattaatt gaaaaccagt agacaatggt agccctacag aaacacccat gtacttcatt
    22921 ccatggaact gtccattttg tccaacactc caagctaagc cggataaaaa tccgatcaag
    22981 aaaatccaag gggtgattac aggactaaca acgaaaaaga caactaaaga aaacagaaat
    23041 gcaccgatcg tcattcctag tgtttgttga ttggcatcgc caccaatttt accacttact
    23101 aaaccaatac taccccatgc caacataggg actaatgcta ttaaaatttc cataaccaat
    23161 ctccttttat ttcacatgat aagaaactta tcagcgaaaa cgttaacaac acaagcactt
    23221 tttttcgttt ctaacgattt tctaacgttt ttcattataa aaatttaaga ttgggaaaaa
    23281 taaagtcatt gttgtccctt ttccttcagt tgattcagcc gtcaaatgga tacctaattt
    23341 ttcggccaga ttttttgcta aataaagtcc taatcctgtt gaatgtgttt tgctaagtcg
    23401 accatttctc ccagtaaatc ccttatcaaa gatccgtttc aagtcttccg ctgggatacc
    23461 gatccctgaa tctttaactg aaaggctgac tccttgcgct tccttttcta tgctcacaat
    23521 gatgtttccg tgatccggcg tatatttgat ggcattacta agcaattggt tgaagataaa
    23581 agcgatccat ttagcatcgg tcaaaacagt atgatcctca ccaacgatct cgtagcgaat
    23641 atttttttgg ataaaataat ttgcctgact gcgtatcaca ggctgaatga ttccttttag
    23701 tccatattct tggatgaggt agtcccgcga gaaactgtcg agtcttgcat aatacaaaac
    23761 ttgttctacg tattcatcga tttttgataa ttcattttct agtaatgtat acttttgatc
    23821 gtcaatatcg aactcgatcg aacgaactag caatttagaa gcggaaagtg gcactttgat
    23881 ttcatggacc catgagtcaa tataatcttt ttggtcttgt tgattactga ttgctgattg
    23941 cattacttct tggtgttcac ggatcagctg attgatatat tcttctacca gtttttcttc
    24001 ttctgtcctc ccaccactca aataattttg caaaggggaa gttttttgta tgtcggctaa
    24061 ttttccccac catcttctct tgctcaagta accacccagc agataaaaaa tcagaaagac
    24121 gccctcaatc aaagctaaat aagcaattgt gctcaaatca actttgatgt ttggcgccag
    24181 ccacatcaca aagatcgtca atgcaataaa aaacagccat cccaagatca atgtccactg
    24241 atctttcaaa tatttaaaaa aattcatctt aaccgctcat cctttcaggg aacgatatat
    24301 ccctgtccta cttttgtttc gatatatcct tggatacctg cctgttcgat ttttcggcgt
    24361 aaccgattga tgttgactgt caatgtattg tcatctacaa atcgttcgtc atcccacagt
    24421 gctcgcagca atttttcccg acttaagatc tttccattgt gcttcatcaa aataaataat
    24481 agacgatatt catttttgct caaatcaatg atctctccgt tgatttccat acttccgttg
    24541 tcaacattca acgtaatgcc attgtggctc atcatttcac tagataattc tgtgtagttg
    24601 taagaacggc gaagtaatgc attgattttt gcaatcagta catcgatttg gaaatgtttt
    24661 gtcacaaaat catctgcccc catgttcata gccatgatca tatccatatt cgtattcctg
    24721 ctggagataa aaatgatcgg tactttcgat acttcacgta ttttttgaca ccaataatag
    24781 ccatccaaaa cgggaagatt aatatctagt aatacaagct gtggttcttc tctttcaaag
    24841 tctgagaaca cttgattgaa atcggtcgtt ccaaaggttt caaattgcca tttctcaagt
    24901 tcctccatga tcaattgtcg aatgatctct tcgtcttcga ctaccatgat ttttgccata
    24961 aaaaatccct ccatctttct tcttgctact acaatatcaa agaagccctt gtgaaacaag
    25021 ttggcttacc tggaaaatgt cattttagca aacgttaaaa aaaactggaa atatgcgatt
    25081 taatcg
//
LOCUS       DADGKS010000037        24258 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.037, whole genome shotgun sequence.
ACCESSION   DADGKS010000037 DADGKS010000000
VERSION     DADGKS010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.037"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(45..1340)
                     /gene="purB"
                     /locus_tag="JXV47_001624"
     CDS             complement(45..1340)
                     /gene="purB"
                     /locus_tag="JXV47_001624"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HAX1487675.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1353..2486)
                     /gene="purK"
                     /locus_tag="JXV47_001625"
     CDS             complement(1353..2486)
                     /gene="purK"
                     /locus_tag="JXV47_001625"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HAX1487676.1"
                     /translation="MINLVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVS
                     DCPAAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTD
                     LLAITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKG
                     QYVLKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHN
                     NILHETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRP
                     HNSGHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENK
                     PDWQFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2470..2958)
                     /gene="purE"
                     /locus_tag="JXV47_001626"
     CDS             complement(2470..2958)
                     /gene="purE"
                     /locus_tag="JXV47_001626"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HAX1487677.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3374..4681)
                     /locus_tag="JXV47_001627"
     CDS             complement(3374..4681)
                     /locus_tag="JXV47_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HAX1487678.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4684..5265)
                     /locus_tag="JXV47_001628"
     CDS             complement(4684..5265)
                     /locus_tag="JXV47_001628"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HAX1487679.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5381..5478)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5837..7129)
                     /locus_tag="JXV47_001629"
     CDS             complement(5837..7129)
                     /locus_tag="JXV47_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAX1487680.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7126..7749)
                     /locus_tag="JXV47_001630"
     CDS             complement(7126..7749)
                     /locus_tag="JXV47_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487681.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7752..8588)
                     /locus_tag="JXV47_001631"
     CDS             complement(7752..8588)
                     /locus_tag="JXV47_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAX1487682.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8605..9492)
                     /locus_tag="JXV47_001632"
     CDS             complement(8605..9492)
                     /locus_tag="JXV47_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1487683.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9508..10791)
                     /locus_tag="JXV47_001633"
     CDS             complement(9508..10791)
                     /locus_tag="JXV47_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAX1487684.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(11474..12157)
                     /locus_tag="JXV47_001634"
     CDS             complement(11474..12157)
                     /locus_tag="JXV47_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAX1487685.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12175..12792)
                     /locus_tag="JXV47_001635"
     CDS             complement(12175..12792)
                     /locus_tag="JXV47_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HAX1487686.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12802..13626)
                     /locus_tag="JXV47_001636"
     CDS             complement(12802..13626)
                     /locus_tag="JXV47_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HAX1487687.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13619..14179)
                     /locus_tag="JXV47_001637"
     CDS             complement(13619..14179)
                     /locus_tag="JXV47_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487688.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14353..15309
                     /locus_tag="JXV47_001638"
     CDS             14353..15309
                     /locus_tag="JXV47_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAX1487689.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15614..16570)
                     /locus_tag="JXV47_001639"
     CDS             complement(15614..16570)
                     /locus_tag="JXV47_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HAX1487690.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16674..17276
                     /locus_tag="JXV47_001640"
     CDS             16674..17276
                     /locus_tag="JXV47_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAX1487691.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17364..18863)
                     /locus_tag="JXV47_001641"
     CDS             complement(17364..18863)
                     /locus_tag="JXV47_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HAX1487692.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(18879..19403)
                     /locus_tag="JXV47_001642"
     CDS             complement(18879..19403)
                     /locus_tag="JXV47_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487693.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19701..20450
                     /locus_tag="JXV47_001643"
     CDS             19701..20450
                     /locus_tag="JXV47_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HAX1487694.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            20441..21226
                     /locus_tag="JXV47_001644"
     CDS             20441..21226
                     /locus_tag="JXV47_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAX1487695.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21195..21911
                     /locus_tag="JXV47_001645"
     CDS             21195..21911
                     /locus_tag="JXV47_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAX1487696.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22013..23032)
                     /locus_tag="JXV47_001646"
     CDS             complement(22013..23032)
                     /locus_tag="JXV47_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HAX1487697.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(23051..24109)
                     /locus_tag="JXV47_001647"
     CDS             complement(23051..24109)
                     /locus_tag="JXV47_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014372913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HAX1487698.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
BASE COUNT         7188 a         5222 c         4225 g         7623 t
ORIGIN      
        1 tttttgctat tctattttaa ttgaattttg caactcactc ttctttattc caaacctact
       61 cgtttgaata tcacgtcaac gtttttcaaa tgatgatgat aatcaaaggc atcgtctatt
      121 tcttctttag ataataccga tgtgatggtt ggatcttctt ctaacagcgg gcggaactgc
      181 acttggttgt cccaagcgta cgcagttttt ggctgaacaa gatcataagc ttcttctctt
      241 gtcattccct tatcgatcaa tttcagcata acgcgctggc tataaatcaa accaaatgtt
      301 gcagacatat tccgcttcat gttttcagga aagaccgtta gatttttaac gatattgcca
      361 aaacgattta acatgtaatt caataaaatc gtggtatcag gcaagatgat tcgttctgct
      421 gaagaatgag aaatatctct ttcatgccat aatgtgacat tttcataggc agtgaccatg
      481 tgtccgcgca ccactctggc tagaccagcc atattttctg aaccgatcgg attccttttg
      541 tgcggcatag cagaagaacc tttttgacct ttcgcaaaaa attcttctac ttcacgtgtt
      601 tcggattttt gcaatccgcg tatctctgtt gcaaaacgtt caatacttgt agcaataagc
      661 gccatcgctg agaaatattc agcatgtaga tcccgaggga gaacttgagt agagatttct
      721 tgtggacgga tccccaattg tttacataca tactcttcaa taaatggcgg gatatttgcg
      781 aacgttccca ctgctcctga gatttttcct gcttctactc cttttgccgc atgttcaaat
      841 cgttcgatgt tccgtttcat ttctgaatac catgtggcaa gtttcaatcc aaaagtagtt
      901 ggttcagcat ggacaccgtg tgtccgaccc atcatcactg tatatttgtg ttcttttgct
      961 ttttcgccaa tgatttccgt aaaacgtttc aagtcttccc gtaaaatatc atttgcttgc
     1021 ttgatgagat agccataagc agtatctacg acatccgtac ttgttagacc ataatggacc
     1081 cattttcttt cttctcccaa tgtttcagaa accgctcgtg taaacgcaac gacatcatgg
     1141 cgtgttaatt tttcgatttc caagatccga tcgatatcaa atgatgcatg ctcacgaatt
     1201 tttttcacat cttcttgcgg gatttcacca agttctgccc aagcttcatc tgctaaaatc
     1261 tcgacttcga gccacgcacg gtatttgttc tcttccgtcc agatattccc catttcaggg
     1321 cgtgtataac gttctaacat gttttttctc ctctaatccc aaatattcgt ttgtttgatt
     1381 tcttccagcg tttgctggat gtcttctgtc aagatagtga tatgtcccat cttgcgacct
     1441 ttttttgctt gtttttttcc atagaaatgg aattgccagt ctggcttatt ctcaatcaag
     1501 cgatagcttt ccagcagttg ttctcccaaa acattgacca ttactgcatt gcttatcaaa
     1561 cgtacttttt ctcctaatgg ccaaccacaa atacctcgaa tatgggcatc gaactgactc
     1621 atagaacaag cttcaataga ataatgtcca gaattgtgag gacgaggagc taattcattc
     1681 acatatagcc cgcctgtttt tgttaaaaac atttctaccc ctaaaacacc tgaaaggctc
     1741 actgcttctg caatcacacg ggcaatacgc tcagcctcct cgatcacatc ctgatcaatc
     1801 gcggctggag caatcgtttc atgaagaata ttgttgtggt ggatgttttc cacgaccgga
     1861 aaagtcgtga aatctccttg accatttcct gccaccatga tcgaaatctc tttttcaaac
     1921 gggatccatg cttctaaaac acaggttcct tctcttaaaa ggtccatggc aggagctaga
     1981 tccgcccgac ttttcaaaac atactgcccc ttgccatcat agccgcctcg agtggttttc
     2041 aaaacacaag gatagccgat cccgtcaatc gcatcttgga tatccgtcgg actgacgatc
     2101 gttgcataag gagcaatcac gatgttattc gtttccaaaa aagatttttc taacaggcgg
     2161 tcttgcgtaa tcgcaagcaa gtctgtccct tgaggaataa atgacatggg taaaatcgca
     2221 tttaacgcct ctacactgac gttttcgaat tcataggtaa tgacatctgt tcttctggca
     2281 agctctttca gcgcaaaggt gtcatcatag acactttcaa tgtgccaatc tgcaacttgt
     2341 gcggctggac aatcgctcac aggatccagc acacctactt taaagcccat ttcttttgca
     2401 ctaatcgcca tcatacgacc taattgaccg ccaccgacga tcccgatcgt tgaaccaggc
     2461 aacaaaggtt taaccaagtt gatcactact ttctataaca gttttagcca acattgaacg
     2521 tctttcagcc aatttagcct ccaattctaa atcatacatg gaaagcatct gtatcgcaag
     2581 tagtccagca ttaattgctc ccgcttttcc gattgctgta gtagctacag gtactcctcc
     2641 aggcatttgg acaatcgaaa gaagcgaatc caaaccattt aatgttcgtg attggaccgg
     2701 tacaccgata accggcaaag ttgtttttga tgcgaccata cccggcagat gcgcggctcc
     2761 ccctgctcct gcaataatga ttttgattcc tttttttcga gcgttttgtg catattcaaa
     2821 catcaaatct ggggttcgat gagcagaaac gacctttttt tcataagaca caccgaattc
     2881 atccaatatt tgacatgctt ctttcattgt ttcccaatct gaagtactcc ccataatcac
     2941 agagattttt gctgtcattg tttttcctcc cagtttttct acattcatat tttaacaatc
     3001 actttttttg atgtcaaaga aatttcgaat gttaacaaag aaaaacattt tattgttcgt
     3061 gtttattaaa gataaaaaaa aggaatgtga caaaagttag gtcacattcc tttttatgga
     3121 taaacggtgt tctcctgcca actcctcggt cacaaggaac aatattcaac aaacatgaga
     3181 agcttttttt tgaaattgtt ccttgtgact cggagatgaa cggcaggctc acgacctctt
     3241 ccttcaacgg tgttcaatca gctgaccctc ggtattagct caaacaaacg gcaaaatacg
     3301 aggaactatt tttccgtttg tttctctaac aatcaggtca aaacgctgat ttcacaacct
     3361 ttcttttgct ctattacttc ttgaaggctt cttccaatat ttcttcatct tttttcaatc
     3421 cattaaagat caaattcaat atgatagccg taatgctact cattacgatg ccatttccag
     3481 tgaacatttg caatgtttgc ggcatttgac tgaataatgt cggcgtaaca ttgaaaccca
     3541 gcccaaatcc aacagaaaca gcaacaatca atagattttt atcattgctg aaatcaactt
     3601 ccaacagcat acggattcct tggactgcca ccatcccgaa catgactaac attcctccac
     3661 caagtaccgg ctcagggatg atttgtgcta acgcaccgat tttagggaat aatcctaaaa
     3721 caatcaagaa gaatgcagag aaatagatgg gttttcttgt tttgattccc gaaagttgaa
     3781 ccaatccgac attttgagaa aagccagtat aagggaatgt attgaaaata ccgcctaaga
     3841 taacggcaag tccttctgca cgatatccct ttttcaattc ttcttctcca acatttttcc
     3901 cagtaatgtc accaagtgca aaatatacac ctgttgattc taccatgctg accatggaaa
     3961 tgatgatcat tagtaaaatc gaccatacgt cgaaagttgg tttaccaaaa taaaagggtt
     4021 gtggaacatg gaacaacggc gcatctccaa tcgcgctcag atcaatcatt cccatgaaag
     4081 cagctaagat gcttcctccg actaaaccaa tcaataccgc gattgaacga atgaaccctt
     4141 ttgccagcat ttgcacgcct acaattagga gaatcgtcac aaatgcaagt agcagatttg
     4201 ttttgtcacc aaaatcagct gctgttgcat tacctccacc cattttctcg attgctacag
     4261 gaatcaaagt caaaccaata acggtgataa ccgttcctgt tactatagga gggaatagtt
     4321 ttttaatttt agaaaagaca ccagaaacta acacaacaaa gatcccagaa gcgataatag
     4381 atccgtagat agctcctact ccttcattgg ttccgatcaa gatcagtgga gctactgctt
     4441 ggatcgcaca tcctaaaacg acaggcaagc caattccgaa aaatcggtta actgtcaatt
     4501 gcaataatgt cgctaatcca cacataaaga tatcaattga aatcaaataa gtcatctgtt
     4561 cttgattaaa gcctagtcct gtaccgatca aaagaggcac cgctactgct cctgcataca
     4621 tcgctagcag atgctgcagc cctaaaaccg cagcttttcc attttgtgtt tctttttcca
     4681 cgattatgcg tcctcctcaa gaaactcaac ttgtccattc gtcaaggaag caatacgcgc
     4741 aagagaaacg actctcaatc ccatttcttc aagtaactga cgtccatctt ggaaagactt
     4801 ttcgatgacg atcccgattc cttctacttg cgctccagct tgctggcata attcgatcaa
     4861 tccttttgcc gcttgtccgt ttgccaagaa atcgtcgata atcaatactt tgtcttctga
     4921 agataaaaat ttacgagaaa tagaaatcgt acttgtcact tgtttcgtaa aagaataaac
     4981 agaagctgtc aataattctt catccatcgt caaacttttt gcttttctag cgaagatcat
     5041 tggaacatct aattctcttg cagcaaataa agctggtgcg atcccagaag cttcaatggt
     5101 cacaactttc gtgattcctt gttctttaaa tacttctgca aaccgttttc ccatttgttc
     5161 catcaataca gggtctactt ggtgagtgac gaagctgtcg acttttaata cgccctcgcc
     5221 taatatacgt ccgtcttttt gaatacgttc aactaattct ttcactttat ttgctccttt
     5281 atcatttatt aataccgaaa taaccgcttt tgtgcaaaaa cctactatgt ttctgttaaa
     5341 gaaaaacacc ctccacttta tcataagaaa agaagggtga aatagccaat cttttactta
     5401 tagtccagca tttacggtac tggctagaaa ctgtcatcca tattatgacg atatataagt
     5461 aggtatgtaa aactaataat agtgtaaatt cattttcttg caactgtttt gcacgtgaag
     5521 gcagtttgcc atatttgaat aaaaaatgtt gtttcaaata ttgaaaacag tctaacacta
     5581 ctttctgaaa ctgacaacgt ggtttactta tttttttgta aaatctaatg atttttaatg
     5641 cattattcct ttttgttcgg gtttaaatag ttatttttat tttctcctat ctaaaaaagc
     5701 agcccacata aaaagaaggc atgacaaaaa gcatgtcata gccccttttt ccgaataaat
     5761 agtgttcaaa agacagccta tcggcaataa ggcaagattt tataaactac gggaagtaat
     5821 ttccgtaaat ctattcttat tcttttaagc tgacaagctc gtcaatcact actgcttttc
     5881 ctgaagcaat agaatgattt gctgcgattc ctgtcaaaat cgacaaaata ccatctacgt
     5941 gagttgctgc ccgattccac ggatcttctt ctttttcttc accaaataga tcatctaata
     6001 aacgcggatc tcctccgcca tgtccgcccg cttcttgttc gacgattacc tcatatggct
     6061 caccgaacat cggatagaca tggatggact gaagaacggc tgctccttca tcctttttat
     6121 ctccacctgc attgatgtaa gacttttcga tcactttcat ttcgatccgt cctttgctgc
     6181 cattgaaaga aacattgaat ccttcccacg gcatatacgc gtttagcgaa tacgtcaaaa
     6241 tcgcaccagt ttcatatttg accgttacgc ctagtgtatc ttcaatagag atatcatcgg
     6301 aaaatacact gcggtcacga atatatccac tgtctttttc tgcttctaaa tacatttctc
     6361 gcaattcctc attggctgac aggtctatag caaatggatc agctttagct agttcgcttc
     6421 catagcatcg actgtaaaat atttctactc cgcgtttctc cgcattatgc atcccataaa
     6481 agtttaatcc accgaatgca aatacctttt ggggacggct gttcaaccaa aaattcacta
     6541 gatcaaaatg atgggtagat ttatgaacaa gaagcccgcc gctattgtgc ttatttcgat
     6601 gccatcttct gaaataatct gccccgtgtt gcgtatttaa cagccattcg aagtggatag
     6661 aaaacacatc accaatcaca tcactttcta tcagttcctt tatcttcgtg tgatacggtg
     6721 cataacgata attaaaagtg actcgcaggc ttcttcccgt ctgtttttgg accgttatta
     6781 tttcttgagc tttttcctca tcgatagtca gaggtttttc gcaaataaca tcatatcctt
     6841 ttttcattgc acgaatgata taatcatgat gcgttcgatc tactgacgta ataatgactt
     6901 cagccggccg tacgtcatcc agtagttgct caaattgtga tggcatacat gtctttactt
     6961 ttttctgtcc atacttgttc acaagtatcc gatttgcata atccatcctt gtttgagata
     7021 catcacaaaa accgactagt tcacaagttt gatgatacgt agaggcaatt gcctcataaa
     7081 aaaaacgcgc tctcccacca agtccgactt gtacatattt tttcttcatt taaagtcatt
     7141 ctccttttct tttaagcaaa atactgtgac aaatggcagc cctggataca gtaatgcagt
     7201 gagtaaaaaa tcatgctgta tacaccagaa cagtccatac aaaaggcata aataccacag
     7261 aaaccccttg acgttttttg acaacagcca gatattcctt ttgatcaaat aaacaagact
     7321 atctgcttta tcttctttgc agatatcaat tagcgtacta aaaaaactat gggatacaaa
     7381 aagcaacaga cacaatagaa aaggaatcag ataccaagct ccaatctttc ccactaataa
     7441 ataccaatca actgcaaaaa taatgacaaa cagctgaaac aacgtaatga tgaaacacat
     7501 ccgtttgatt tttcctttcc tccaacatac ctttttttct gccaagtaat ggacagatag
     7561 ataataagaa ggatacatca tcaaaaaata aatcagatag acaacacgag cagacagcac
     7621 taatcctaaa gtgaacaaac atcctagaac taaagcgaaa agagcattac tgataagact
     7681 ggttaaaaaa atccgacaga catagtagtt gagcttgtaa agaaacatct cttctattgg
     7741 ctttttcata ttcagccctt cagaccgctt gtactgatcc cctggacaag atatttattg
     7801 aagaataaga aaatcagaaa aaccggtagc agcgacaacg tagacatcgc aaacatactc
     7861 gcgtaagtcg tactagatcc agcgtctgca aataatttga tggcaatcga taccgtgtaa
     7921 gatctcggct tgtttaaata aatcaatggt cccatgaagt cgtcccattt ccaataaaac
     7981 tggatgatga tcgtcgtgat gatcgaaggt ttcagcaaag gaaaaataat tttggtaaag
     8041 acactatact tgctgcatcc gtcaataatc gctgattcat ctaactcttt ggggatgctg
     8101 accatgaatt gcatgatctg gtaaatgaaa aatgcttgtc caaaaaaatg tggtaaaatc
     8161 agcggcacat acgtcccaac caaattcagc cgattgtaaa taataaactg cggaatcaaa
     8221 atcacttgtg caggaatcat catcgttact aacatgacga cgaaccagaa tctttttcct
     8281 ttgaaatcga ttctcgataa tgcgtaagca atacaagtcg agctcagaac tgtccctatc
     8341 gtcgaaactg cagagatgac aaacgaattc ctaaagaaag taaaaaatga aattccagca
     8401 aaccccgccc atccttttgc gtaattttcc cattgaaaag tctctggaat caaattcagc
     8461 gaaccactca taatctcttg atccgtttta aaagaacctg cgatcatcca taagaccgga
     8521 taaatcatga ctagacctaa tagcaaaata aaaccgtatt gaaaccattt cgttactgta
     8581 ttattcattt cttcctcctc tcattcacac aacgacccat ttttttgatg atttgaaaat
     8641 cagaaaggtg acagctccca taatcaacag catgatccac gaaatagcac tagcataccc
     8701 catagaatta aaagaaaaag cttggttata cacataaaga gcataaaagt tcgtggcatc
     8761 attcggacca ccttgggtaa tgataaatgc ctgcgtaaaa gtcataaacg ccgcgattgt
     8821 ctgcataacc aagttataca aaatgatcgg cgaaagaaga ggtaacgtga tcttgtaaaa
     8881 cgtctgccat ttgttcgctc catcgatctc tgccgcttca taatacgagc ctgggatctc
     8941 tttgatacct gcagcaaaga tgatcattgc cgaaccgaat tgccaagcag acatcaaaac
     9001 aagagggatc atgaccagtt tttgatcgct aaaccaggaa agcgcaggtg cgcctaatcg
     9061 ttccaggaaa atattcacta acccgttttt agaaaacaac tcccgccaaa ctagagcgat
     9121 agaaatactg ccaccgatca aactaggcac ataatacaaa gaacgaaaga aagtcgttcc
     9181 tttgatattc ctcgttaaaa gataagcaat caatagacca aagatcagtt tcacaggtac
     9241 agatgcaaat acatagagaa aagtgactcg gatggagttc aaaaaacggg catcactcag
     9301 catctttata taattatcca agccgatcca tgagactgga tttcccaaac gataatcggt
     9361 gaacgaataa taaagtgaca agatcatcgg tatcactgtt atcaatagaa atcctaggat
     9421 gaatggagaa gcaaatacgt aaccgaccac attgtcttga tccaagaacc gttttagttt
     9481 ttcttttttc atgccttcct cctgctgcta tcctagaatg tttgacgcaa actcataaag
     9541 actctctgct gcttcttctg ctgttacttc ttcataaatg actttttcaa ctaaaagatt
     9601 gtattggtct tgaatttccg gattcaaagc actatcaaag acattcactt cgccgttgtc
     9661 catatcggaa atcatttcta aataatcaaa tgtcgcttgc aaagttgcat catctgcacg
     9721 agcgagctgt tctcgaatat tcgacatgat tggtacacca cgttctcctt ttaaaatttc
     9781 attggcttct tcactgtttt gaaagaaatc aataaactta gcagcttctt ctttatgggc
     9841 tgagcttttt gccatactca gcatttgcga agaacgtaaa gggataccag attctccatc
     9901 tgcttttctg cgaggtggat taatcaactg aatctccata tcttcaggag cccctgacaa
     9961 tatttctgtc aactggttac ttgatagaaa caccattgcc gcttctctat ccctaaccgc
    10021 ctgaaaagac agatccgtcg tacttgcagc tccaccacct ggttctggat gggccccttt
    10081 gtctaccaga tttttacgca gctggaaaaa atctgttaga tagtctggat tttcaaatcc
    10141 caagctgtta gatagatctt cccgattata aaaattcaat cctttctcaa cttgtggtat
    10201 ttgaataata cagccagcta taaaatcttc gaatcttgaa atagcataga ttcctaattc
    10261 ttcagtgatt tgatagctga tttgttcaaa ttcatcccat gtccaatttg aagctggttc
    10321 agggatattt aattgttcaa atatattttt attgtaagca atcgcaaacg aattcacccc
    10381 gttagacagt ccaactaatt gcccgtcgta agtcgtcgtt gctaaatagg attcatctgc
    10441 attagaaata tcaattatcc cttgctccac atattcatct aatggttcaa tctgattgat
    10501 gtattgagga aattgattgt tcagttggaa aatgtcccag atatcatctg atgctgctag
    10561 tgtacctaat tttgtgtaat atccttcata atcataaaat tcataatcga tcgtcacatg
    10621 gggatttttt tcttcataaa gctcgattac ttttactgtt gcatcgtgtc ggacttgcga
    10681 accccaccaa gccatgttca gcgtgatttt tttgtcatct tcttgcccac aagccgtcaa
    10741 gaagaataac ataacactta aagctaagat gattctcatt cttttcttca ttctctgcac
    10801 ctctacttcc attgttattt ttcaatatac tgtattttta tacagaacat atttattaaa
    10861 cgatcttttt caaggggaat aaaaaccaag acttgcctta tcgttctgcc taggatgaac
    10921 aactcaatac tttcaagaaa aattagatag tgctgattct tctttcatcg ctaaaaacac
    10981 ttcttgcttc aatgatggga ggataattac gcaaagaaaa aaggatatca gacaactgcc
    11041 caatatcctt gacatagcta aataagcatg cttcttcgtg tgcgctcttc cctaaaaaac
    11101 agaaaaataa ctagtaattc tgtatgaaat taggtacaat atacacgtcg atgcacaagc
    11161 attgactatg gcaacttgat tggtcagttc ccgctgactt ttcaagcccc gacaatttag
    11221 ctgctactaa attgtcgggt gcctttttta gtttttattc gtttttcatt ctatagaaag
    11281 cgcttcaata aatcaagaca tttttttgtt agaatgctaa taataacaaa aggttttaac
    11341 tcttcttatg tacattacag gtaaaaaaac aaaaaaattt ctcttttttt tgaattctga
    11401 acaaatagta ctggagtaca aaagacgagg aagagccact atctgctctt cctcgtcttt
    11461 tgattctcac ctgttattca tgattctttt tctcagtttc ccgatatttt tccattttac
    11521 gactaaaaag ctctccgcta cttggtggcg tatatgtgat ggcatttgct cctgcttgaa
    11581 tggtctcagc aatactttct tccgttggac cacctgtcgc aatgatagga agttcaggat
    11641 attttttacg aaaatggcgt actgcttctg cagtttcttt acctgcactg atattgataa
    11701 tcgaaatacc agctgctaac ttttcatcta tttctgtata tttcgacgtt accgtactga
    11761 taactggaat atcaactact cgacaaactt cttttactgt ctctaaaggc gtaggaccgt
    11821 tcaaaacgac ccctaacgaa ccttgcgctt ctgcgaacat gctcatgtag gaagaacgag
    11881 caccttgtgt caaaccacca cctacaccgg agaaaactgg aatgtcagct gcctcaataa
    11941 tgcttttagt aatcgctgga tgaggtgtaa aaggatacac agcaattact gcattcgcat
    12001 ttgtattacg tatgatcgca atatccgtag taaagatgat cgaacggatc aattttccaa
    12061 atatcttgat cccgcttgct tctaaaatga tttccggtac tcttacgata tcttttctca
    12121 attccgtcat gatttctggc gtaaattgtt ctgccatcag ccacttctcc tttgctatct
    12181 ccggtcatac tgattcaatt gatacgtctc gatgacctgg atgatttttt gcgcataacc
    12241 ggggtctgtc gcataacctg catcttgcaa tgcttgtgcg gcttcctgat agttggtggc
    12301 cgtaatcact ttttcataca gcgcaggatt ccaatctact ccttggacga acagttgtgt
    12361 atggtcatcc atggactgtt cccatgaatc atacactttg aagtctcctt ggatagttat
    12421 ccattcttcg ttaacaaatt cctttgtttc caggcttact ttcttctgat ccccataagc
    12481 cttgatcccg aaaagattat tgtatttgct agccaaggta ctttttcccc aatttgattc
    12541 taatatagct tgtcctaaaa tgatactagg aagcactcca taaccatctt gtagttcttg
    12601 ggcatgcgga acaagccgtt caataaattg ctgatgggat tgcgcttcat tttcttgctg
    12661 attatcagta aaaggagaag acagattctt caaggaaaaa acaaaggcta agagtatcac
    12721 tgctacaccg gcaaccactg ctggccaacg gatattcttg cgcttttgct ttttccactt
    12781 ttttttcgcc atgatcaatt cctacttttc atttaattca ttcagatatt cttctagcgt
    12841 caattggtgt ttggtgatat actcagcgtt ttctttaccg acataacgta agtgccaagg
    12901 ttcatatgtg atcttagtta tatcttcgtg tccttttgga taacgaacga taaatccata
    12961 ctgcgcagca ttatctgcga tccatttagc tccaggctga tctccgtaac ttgcatccaa
    13021 tacagtagaa ggataactgt tgtaccagtt ttgatcgacg acatcgactg ccagacctgt
    13081 gtggtgttcg ctgtatcctg gctccgtaat cgtttcttta gtaatctttg tcgcctcctc
    13141 ttctgataca ccttgacgac tcatcacatc ttggacattt tgttcgaaaa cttgttgttg
    13201 ggatgataca gaccggtaag ctgagaccat cactaatgga aatccagctg cttcagcagc
    13261 cttggcaaat gcttcatatt ctggagcaat gcgtttgtcg atcaagtatc cgttacttaa
    13321 tgatgccaat tgagtagact catcaatttc tttttctaat ttgtgatctg gaccaaccaa
    13381 aactagcttc caatcgtctg ttttaacatc tggcaattgt ttggacgtac gatcttttgt
    13441 ttctttgtcc tttaccttgc tgctggttgt ttgactgttc ttttctttac tagcagttgt
    13501 tttggtgctt gttcgttcga ctgcttgatt gccggcttga acatgcgaat catcatcgct
    13561 aaaaataaca tagcccattg ctgcgatcat aatcacaact gctccaaatc ctaaaaattt
    13621 attcacttga aaaatccttt cgttgttctt cacgttcccc attcgcctca tgaacgtaag
    13681 tttcttccag attttcattc acccaatcga gaagttcgat tttttctcct tcgatctgtt
    13741 tttgaacatc tgctggcaga cgaaaattca aaatatcatc atagccccat tcatcatatt
    13801 gaatacttac tttcaagtca aggtatctac cagcctgctg attatttttc aaagggatca
    13861 gctcgacttt tgctgctttg ctgctaagcc atttttgcgc gatgcgtgtt ttgatttgct
    13921 tgtactctgc aacggcaacg tttcgttttt cgggaaaaat aatcgtttga cgcaaaatct
    13981 tttgcgttag catccattca taatcagtga aaagattttt tactttctgc atcgcttcag
    14041 atggcagatt tttctcgcca tctttccatt tttgccattg ttctggactg atcagcaagt
    14101 attcatctaa aaaatttttt tcagtttcaa actgttctaa taatacactc ataataagat
    14161 caatatatac ttgatgcacg tttatcccct ccttttaact attctactta agttttgatc
    14221 aaaaagcacc tcttaaatcg ctgctttcat tttttttaat gtttcaagtc ctctcctctt
    14281 tattcttcgt gatttttgtt ataataatag acagacaaga aactcaatcc aactatgaag
    14341 gagcgttttc agatgaaaaa atatcaatgg ggaatcgttg gtcttggtac catcgcacat
    14401 gagtttgccg aaagcttcaa tcaagagacg agcgaactaa cagcagttgc ttccagaact
    14461 tcagaaaaag cggaaaactt cgctcaccgt tacaatattc caaaagctta cggaagctat
    14521 caagaaatgt tagacgatgc tgaaatcgac atcgtgtaca ttgctgtacc aaatagacag
    14581 catatcgacc atatcttggc agcattggaa gcaggcaaac acgttctatg tgaaaaagcc
    14641 atcacgatga ataaaaaaga actggctgac gctatgcgct tagcagaaga aaagaatttg
    14701 atcttagcag aagcgatgac aatcttcaac atgccacttt atcagcagtt acgctcaata
    14761 atggatacag gaaaactggg ggctttaaaa atgatccaag cacctttcgg cagttacaaa
    14821 gaaccagacc ctaaaaaccg gttcttcaat ccagaattag ctggaggagc tctgttggat
    14881 atcggtacgt atgctgtatc tttcgctcgt ttctttttga gctctcaacc tgaagtagtt
    14941 gcctctacaa tggttccttt tgaaacaggc gtggacgaac aatccgtcac tatcttgcgt
    15001 aacaaagaaa atgaacttgc tgctgtcagc ttgacttttc aggcaaaaat gccaaaagtc
    15061 ggtatcgttg cctttgagaa cggttatgtg acgattgctg attacccgcg tgctgatcgt
    15121 gcggagatct tatttacaga tggtacaaag gaattcatcg aaagcgggaa tacatctgaa
    15181 gcaatgaatt acgaaataaa gaatatggta cacatgattg aaggtgactt gcccaatcgc
    15241 tctctcttct tgacaaaaga tgtcatcgaa atcttggatc aaatgcaagt tctatggaaa
    15301 aatatgtaat tttaaaaggt tgtgaaaaag ctgttctgca tcaagtaata agaacagcca
    15361 aacaaaaata gctcctccta tttttcgttt ggctggactt attaccgcag aggaaagctt
    15421 ttgaacaccg tttaagaaag aggttgtgag cctaccgttc agctccgagt cacaaggagc
    15481 aatttcaaaa aacagcttct catgtttgtt gaatattgtg acttgtgacc gaggagttga
    15541 caggagaaca ccgtttaaag aagaggttgt gaaatcagct ttttgacctg aatattagct
    15601 gaattcacaa cctctatttt tggatttttt gttgggagaa ttctgccttg atttcaataa
    15661 aacttttaaa agactgcaaa aactggaaca attctgctcg atcctcgaat tcagggcgac
    15721 tagtcggcag aggcatttgc cgatacaata cataaacttc ttcaatacgt gttaaaattt
    15781 gtctgccatc atttgactct gaaaatgttt ctgcagtata aatcaataaa ccatagatat
    15841 gttttccata ataagctggt tgctggattc tctctagatt ttccagcatg tctttaatca
    15901 cattggcctg tgctcttctc atagagaagt aagtttcgta gtatagcggc tgtctgagcc
    15961 agtagttttc ttgatgttct ctggcatctt cttggctttc gcgaatgaat gtcagtaaat
    16021 gttcgcattt gatctgcaca tcttctttat tttctgataa aagaaattct gccatttgtc
    16081 tcaaaatatt tcgaaattct ttttcgatct gtatttggtt ttccttcagc tgcttcgtac
    16141 gatctggcat gtaaacattt gcaagcaaag caaatactaa tccaatcgcc attaatcccg
    16201 cttcattgcc gatcagctgc caagacatgt tttcctccac taaataatga gtgaccaaaa
    16261 ccgaatttac tactatccct tcggttaatt tgaagcgaga ggcaagcggg atgaacagga
    16321 ataaaaaaag actgaagcca aaaatagtat acccaacagc aaaaaaactg aacagtgctg
    16381 ttgccgtagc taatataaag gctgcgattc gattcatgcc cgtacgcaat gtagagcgct
    16441 tggtatttcc tacacttaat aatgcaatga tccctgcagc tggccaatac aacagcgata
    16501 agctacccgc tgtgaccatc gaaaagaaga cactgatcac tgttttgact gttcgcattc
    16561 ctatacgcat ttacttcccc cttttttatt ttaattatac ttgaataatg aaaaactagc
    16621 tatcagacaa aagtttaggt atgatagtaa aaagaccaaa aaggagaatc tctatgcaat
    16681 ttggccgttt tcgactaggt atgcgtacga tcaaaagtgc cttagctgtt tttttatgta
    16741 tcttgttttt tcatttgact caacgaggaa tcccgatgat tgctgcatta tctgctgttt
    16801 tttctttgcg tcaggacttg actacaaccg tttcttttgg aaagtctagg atcatcggca
    16861 atacattagg tggtacatta gctatcattt atttttttgt caaaagctat tttcacaatg
    16921 attttttggt agaattgatc ttgcttccta ttctagttat tattgtgatc gtcgtgtcag
    16981 atggtattaa caataattcc ggtatcattt ccgcaatagc tacgttgttg ctgattgcgt
    17041 tgagcatccc tcaaggcgaa tccgctttgt atgctatcca acgtgtacta gatactttta
    17101 tagggacatt cattgcaatc ggtatcaatt tctttcttcg tcctcctgaa acagaaaaga
    17161 aggaagaact atcagaagat ttggtcgaac tccaaaagaa agaacgattg ctaagaacaa
    17221 atttacaaga gatagaagct aagatccaaa aacaaaagaa aaatagcgag gactaatttt
    17281 cttttgcaat aaaataaaaa aatggagaga agaactttaa aaagtcttcc tccatttttg
    17341 attgaacggt gaagtgtact actttattct tccttcatcg agttttgttc tgcctctttt
    17401 ggcgcttcat acatatttac ttggctagta gtcccacgtg tcgacaaatt ctctacgatt
    17461 tccttcaagt caagtcctgt tgtcgctttt agtgtttctt gagtagaaga aagcaaattt
    17521 gtggcataat ttgtcactcg gttcgctcca ctggtttctc ctgaactgct tcctgtatcg
    17581 acaacagaga ttttttcgat atttcctagc ggctgtgctg cttcgcgcat caattgcggt
    17641 agcatatcga taaccatact caagacagct gcttcgccat attccttgaa ggcattggcg
    17701 atcttttgtt ttgcttcggc ttctgctttt ccttttgcta gtgctgcttc ggcttctgct
    17761 tgtccagcta aacgtgtctt attggcttcc gcttctgcca gtgcttccac acggaatcgt
    17821 tctgcttcgg cttcagtcac ttctttgact ttttgagctt gtgcttcttg ttctttagcg
    17881 taccgatcgg catctgcttt tttcttcact tccgaatcat attgcttttc acgacgtgtg
    17941 atttcttttt cttccagttc gatttgtttt tgacgttcta cgattttaat ctgcatttcc
    18001 tgttcgatta cttgttgttg tgctcgggca ctttctaaat tgtaggcttg gtctgctttt
    18061 gctttagcaa catcttgttc ttgtttgtag gttgctaatt tcagttcttt ttcttttaat
    18121 gattctgcga tctctgtttg tcgctgtaat tcagctgctt gtgattcttt ttctgcttga
    18181 gcttttttga tacgcgtttc ttttagagct tccgcttctg ctatatctgc atctcttttg
    18241 acttgggcga ttcttggttt ccctaaagag tcaagataac cgtttttgtc tctgacctct
    18301 ttgatagtga aagaaacgat gatcaacccc atttttgcaa ggtctacaga agcgacttct
    18361 tgtacgcttt gactgaactt atcgcgattt tgatagattt cttctacagt catagaacca
    18421 agaatcgagc gcaagtgtcc ttctaatact tctcttgctt cattttccag ttcttctctt
    18481 gtcttgccta aaaactgttc tgctgctgta gcaatctctt ctacagatga accgattttg
    18541 atgatcgaag taccatcaca catcaccggt acgccttgtt ccgtatacac ttcaggggtg
    18601 gagacgtcca atttactcga taatagactg atccgattcg aacgttgaaa aactggcaag
    18661 acgaatgcgc cacctccacg cacaattttg attttgttat tgctttcatc aatgtgcaca
    18721 tttttgcttc ctaaataact tccactgatg atcaacgctt catccggttt tgctgtctgg
    18781 tacttcgcta caaagacgat cagcaacatc agtaaaatca aagctgcgat tgcgatcgcg
    18841 ataaaaacaa ctggtatttc catttaacac acgctccttt aagcttttat catgctttca
    18901 taaggcatga cataacagat tctttccttg atctcaatga tcaatacttt cgttccccgc
    18961 tcagctgtct gttcttgggg gctgtaaaaa caagctggac gactaatgga accggtaaca
    19021 cttttcaact gaatttctcc catacctcgt acagggatcg gtgtgatcac aacagctact
    19081 tgtccttcca gagttttttc agaagacgac atcgttgatt cggcatgttt catcggcatc
    19141 aatatataga aattaagcaa aaataccaac actatcgata tgcctccact agcaataaat
    19201 aaaaataaag atgattgatc tgttaaacgc tcacctagaa aaccaaataa gcttgtgaaa
    19261 gttaaccaag ggataataag catcggatca agcgggccat caaaatcgaa tacatctcca
    19321 aaaataatca ataggactgc caatcctgca caaatcagca atgtatacca ataaatcgtc
    19381 tcaagtgcga ttccccctat catatacacg cctccttcca tttctacgtc tatcatacca
    19441 atgtttgaaa attctgtata gcttctttta ccgactcagt ggtgtttttt ataggaaggt
    19501 tgtgtttatc gttgacaatt tgttaaattt ttgttttcat gttaaaattt tcacaataaa
    19561 ttctttcgag gtagcctatg tttccttttt ttaagaaaaa accattaaag ctccagaaca
    19621 cgatcatcct tgtcgtttgt ttctccacat tcgtttcttt gattgtttct gccatattga
    19681 tcaggaattt tattctttcg atgaaccgat ctagtgtgtc agataaaatc tctagcattg
    19741 ctaaaatcgt tgccaatgat aaactcatcc aaaaaaagct gcagactggt gacccgacac
    19801 atgcgattca aggaataaca aatgaaatca tgattgcatc gaatttagat tttatcgttg
    19861 tcatggaccc tgaaggcatt cgatattctc acgcagaccc aagttacatc ggtcttcctt
    19921 tctcaagtca tgaagatgtg aaaaaagtga ttggaggaca agaatttttc tctgaaaaag
    19981 aaggaatgtt agggttcggc ttccgctatt tcgtccctat ttattatgat caagagatta
    20041 ttggtgcagt ttgtgttggc ttaacaaaca acacgattga caatcaagtc aaagatggac
    20101 aaaaaatgat tgttttttca ttgattattg gacttagcgt aggcatcata ggcgccgttt
    20161 ttcttgccca aaaaatgaaa aaagtactgc ttggacttga accacaagaa atagcagaac
    20221 agttaagtga aaaaacgatt atcgaaaatg aagtagatga aggaatctta gccatctctt
    20281 ctgataaaac tatcctcttg atcaatacac ctgcaaaaaa cattttctac caaacagagc
    20341 agctattgga tttcgaagta ggaaaaaaat cagtgataat ctatatgacg ttttgtttaa
    20401 agagacgatt gagcatcaaa cgaccgttcg gactcaatcc atgtatttaa atgggataga
    20461 aactatttct agcgttacac ctctttttag caatgaccgt tttttaggag cagtcgcaac
    20521 tttacgaaat cgatcagaag taatgaaatt aatggaggag cttgggggga cgaaacaata
    20581 tataaactcc atgagagctc aaacccatga attcatgaat aaacttcatg tcatttctgg
    20641 tttgattgat ttgaagaagt atgaagaagt cacccatttt atccagcagc taaatcaaaa
    20701 ttataaaaaa gagattggcc aagtctcaag tctgatcaaa gtacctgcaa ttgccggttt
    20761 tttattaggc aaaataaacg aagccaaaga acaatctgtt gaaatgctgt tagaaagcga
    20821 ttcttttatc cctaaaatgg agatggatga ctccatccat tcacttttgc aagtgttagg
    20881 gaacttactt gataatgcaa aagaagccgt gctacaaaaa catgaaagaa acggacaggt
    20941 ccggattcat ttaaactatg acacagaagc tgaagtattc atcgtgaccg tctgcgatga
    21001 cggtgtcggg atatcagaag aaatctcaga aaaaatattt acgctaggtt tttcgacgaa
    21061 gggaatcaat cgtgggtttg gattgaatct catccattca atcgtcaaac gccacggtgg
    21121 atttttagaa ttttccaaac aaacaaatgg cggtacaatc gtctatctag aattaccaaa
    21181 aaaggaagat caaaatgatg acaaatgtcc tgataatcga agatgatcca atggttgcag
    21241 aattgaatcg tacttttgtg gaaagcatcc ctaatatgaa cgtaatcgaa agtttcagaa
    21301 atgtagaaga aggaaaaaaa tatttcagac aaaaaaacgc agatctgctg ctgcttgatg
    21361 tatacatgcc tggcgaaagt ggtatccatt ttttatcttg gcttagacag caaggaaatg
    21421 atatcccagt gattttgatc actgctgcag atgatatcga aaccataaag aatgtgatcc
    21481 gctacggtgc cttagattat ttgatcaaac cgttcacttt gcaacgtttt cagctggcga
    21541 tcgaaaagta tcttgctttc tctcagacaa tccaaacgac tgaaaaagcc gatcagaaat
    21601 tgatcgatca agtattcaac cacaccactc ccattcacga aataccatca ttcatcgatt
    21661 tgcctaaagg tctgtcaaaa ctgactttaa aaaaaataag tgcatttatt ctaaaagaag
    21721 atactatttt ttcaacaaaa gaactggctc aaaaaagctc actgtcacgt atatccgtca
    21781 agaaatattt gaatttttta gtagaacaag atatattgaa cgaaagaatc aaatatttgg
    21841 aaatcggccg gccgctaacc tgttatgaat tgacaaagaa tgggcggaaa aagctcacag
    21901 attactgttg agtcatcgaa ttatcccata caaaatagtc caagtataca gaagtaacaa
    21961 ctgtttactt ggactatttt taaacatttt attgacgaat atccatgttt tcttatctta
    22021 attgacgggc tttaggaaga gatacctcat ttttcgtttt tccagtttct attatttcac
    22081 gaaagttctc gaaacttgtc gaaatcatat ttgataatgc ctcatctgta tttgaaccta
    22141 catgcggggt tacaagaact ctagggtaca tttctactaa ttgctggata gcagggtctg
    22201 gaatcgtctc ccatggcttg aaggatcgga aaaaaacctc tgtttcattt gcaaaaacat
    22261 cggttgcaaa accagctaaa tgattgcttt tcaaagctct taaaatagct tcattatctt
    22321 gaagctctcc acgggctgta ttaatcaaga tgctaccttt tttcatttga gctaaaaatc
    22381 cttcattgat catttgatcg ttttcacctg ggatatgagg tacatgaata ctgacaatat
    22441 cgcttttggc taataactct tcaagcgagt ggaacgtcaa tactttttta gcagcttctg
    22501 tctgatgaat atcgtagccg atcactttgg ctcctagtcc cttaaacaaa acagcttccg
    22561 tcaaccctat cctgcctgtt cctatgatcc ctactgtgca atttctgatt tcacgactaa
    22621 acatttgctc atccactcga aaatctttga aagatgttcg gatcgtcgta tacgcagtat
    22681 ttctcaaaag catcatggca aaagtcaaag ataactctgc tatcgcattt ggcgaatacg
    22741 atggtacacg ggctactgtc ataccaaaat cagctgccgc ttgtagatcg atatgattga
    22801 ctcccacagt ccgtgtaaaa acataacgaa tcccatattc ctgcattttt gcaagattgg
    22861 tctcatctgc tatacaattt cccctcaaca atacagcatc atggtccttt gctgacacga
    22921 tattgtcatg tgtcaacagt tcttcataaa gactgagatc ataatggtaa atattcaatt
    22981 tttcaaaaaa atctatctcg ttcggacgaa caccgtaaca tgcgattctc atactttctt
    23041 cctccatttc ttatgaaaat aaacctatgc catgaatcat ttgtaataca acgatccata
    23101 caggtgtcag taccacagca aaaatagttg acagtaagga tgcattggag gctaaaagtg
    23161 cctccctatc aaaactgata gcataggctg ctgccactgt tgcagctggt gtagccatca
    23221 tgataacgat tgttgccagt gcttcaaaat tgactggtag aatattcgtt gccgtcaaaa
    23281 ctgctagaat cacgatattc aatgcaggta caaataccac tttgactaga ctgtaatacc
    23341 atgaagtttt ttcagatgca gcttttttga agcttacttc acctaatgtt gcgccgattg
    23401 ctagccacgc caatggtgaa cttaaaccag ctaaataatc catcggctga aatagccacg
    23461 gtgcagtctg gtcaattcgc aaaaacgcta cttggcttat ctctccttct gcacctgtaa
    23521 ctgacacttg tggcagatac ccttggaaca gccaaatgaa aaggccggca aaagtagcga
    23581 taatgattgg attgacgaac atcgctttga tatttttagc ttccatcttc aagccactca
    23641 tttttatgta tccataagaa tacaaaaaga ttcggtagcc aatattgaaa attgaggaat
    23701 acatcacgcc gacaggacca taaatcgcac tgacgatagg cgttccgaaa aaggtcgtag
    23761 aaccaaagat cgtcaggaca cgcaacgttg tttgcttatc ccctttatag cttaagaaaa
    23821 aaggttttga aactagaata agaataatat aaataactaa tccccaaatc aagacattga
    23881 ttccttgcat cagtaattct gtattgatat cttgcatgaa agctcgaaat gccagtgctg
    23941 gcaaagccac tgttaagacg actttcgata gaatttttcc aacagattca gaaaaaatcc
    24001 ccttttttct acaaacaaac cctaataata taataaaaac tgttgaagtg attgcactga
    24061 caatcgacat atctgtcaaa gtcgatcgaa aaatgtcaaa taagttcatc tttctcctcc
    24121 taattatgtt catttattca caataaaaaa agcttttatt ttgctaatac gtattaacat
    24181 ttttaatttt atctttacat tgttacttat tgaacaatag gaaattaaag aaacttttga
    24241 aacttatgta aagtgatt
//
LOCUS       DADGKS010000038        24257 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.038, whole genome shotgun sequence.
ACCESSION   DADGKS010000038 DADGKS010000000
VERSION     DADGKS010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24257
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.038"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            138..995
                     /locus_tag="JXV47_001648"
     CDS             138..995
                     /locus_tag="JXV47_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HAX1487699.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            1110..2030
                     /gene="pstC"
                     /locus_tag="JXV47_001649"
     CDS             1110..2030
                     /gene="pstC"
                     /locus_tag="JXV47_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HAX1487700.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            2030..2914
                     /gene="pstA"
                     /locus_tag="JXV47_001650"
     CDS             2030..2914
                     /gene="pstA"
                     /locus_tag="JXV47_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HAX1487701.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            2929..3735
                     /gene="pstB"
                     /locus_tag="JXV47_001651"
     CDS             2929..3735
                     /gene="pstB"
                     /locus_tag="JXV47_001651"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAX1487702.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            3751..4509
                     /locus_tag="JXV47_001652"
     CDS             3751..4509
                     /locus_tag="JXV47_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAX1487703.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGINLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            4522..5199
                     /gene="phoU"
                     /locus_tag="JXV47_001653"
     CDS             4522..5199
                     /gene="phoU"
                     /locus_tag="JXV47_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HAX1487704.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            5437..5736
                     /locus_tag="JXV47_001654"
     CDS             5437..5736
                     /locus_tag="JXV47_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487705.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGRLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKK"
     gene            5762..6469
                     /locus_tag="JXV47_001655"
     CDS             5762..6469
                     /locus_tag="JXV47_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAX1487706.1"
                     /translation="MSIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLL
                     NISILFVVIGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYE
                     ELNYLTRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQV
                     GRDVIGSMTNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVL
                     SIPISVLFFLTVRRLKR"
     gene            6466..7233
                     /locus_tag="JXV47_001656"
     CDS             6466..7233
                     /locus_tag="JXV47_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAX1487707.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            7333..8901
                     /gene="liaX"
                     /locus_tag="JXV47_001657"
     CDS             7333..8901
                     /gene="liaX"
                     /locus_tag="JXV47_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HAX1487708.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEITQVQL
                     STTTGSIYLKDTDK"
     gene            9201..9518
                     /locus_tag="JXV47_001658"
     CDS             9201..9518
                     /locus_tag="JXV47_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HAX1487709.1"
                     /translation="MKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVAF
                     GSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDEW
                     SDF"
     gene            9518..9868
                     /locus_tag="JXV47_001659"
     CDS             9518..9868
                     /locus_tag="JXV47_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HAX1487710.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            10035..10973
                     /locus_tag="JXV47_001660"
     CDS             10035..10973
                     /locus_tag="JXV47_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HAX1487711.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            10988..11818
                     /locus_tag="JXV47_001661"
     CDS             10988..11818
                     /locus_tag="JXV47_001661"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HAX1487712.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            11862..12887
                     /locus_tag="JXV47_001662"
     CDS             11862..12887
                     /locus_tag="JXV47_001662"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAX1487713.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            12902..13840
                     /gene="galU"
                     /locus_tag="JXV47_001663"
     CDS             12902..13840
                     /gene="galU"
                     /locus_tag="JXV47_001663"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAX1487714.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKKLEAEGSKIDHNPKGITEIKEEKKK"
     gene            13965..14405
                     /locus_tag="JXV47_001664"
     CDS             13965..14405
                     /locus_tag="JXV47_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HAX1487715.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            14408..15010
                     /locus_tag="JXV47_001665"
     CDS             14408..15010
                     /locus_tag="JXV47_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAX1487716.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDTKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(15078..16184)
                     /locus_tag="JXV47_001666"
     CDS             complement(15078..16184)
                     /locus_tag="JXV47_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAX1487717.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLASIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            16394..17395
                     /gene="ccpA"
                     /locus_tag="JXV47_001667"
     CDS             16394..17395
                     /gene="ccpA"
                     /locus_tag="JXV47_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HAX1487718.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(17731..20076)
                     /locus_tag="JXV47_001668"
     CDS             complement(17731..20076)
                     /locus_tag="JXV47_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAX1487719.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            20355..21257
                     /locus_tag="JXV47_001669"
     CDS             20355..21257
                     /locus_tag="JXV47_001669"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HAX1487720.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            21470..23245
                     /locus_tag="JXV47_001670"
     CDS             21470..23245
                     /locus_tag="JXV47_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HAX1487721.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSFYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYSSSKKMLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYSIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHAVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFAFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTAFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            23502..>24257
                     /locus_tag="JXV47_001671"
     CDS             23502..>24257
                     /locus_tag="JXV47_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAX1487722.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEENTLCSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFLNRLTPYALILIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQK"
BASE COUNT         7748 a         4334 c         5089 g         7086 t
ORIGIN      
        1 tagcatagaa acttttaatg agatagtttt ttttacaatt atgagaattt attttgttat
       61 ttaatgattt tgattcgttt tcatcaagta atgaaaatga taaaataaac atactttagg
      121 attaaaggag atttctaatg aaaaaactta aattattctt accaataata ggattagcca
      181 ttcttttatc aggctgttca aagtggattg atcgaggaga atccattacg gctgttggct
      241 cttctgcttt acagccttta gtagaaacag ttgctgaaac ttaccagaca gaaaatcctg
      301 gaaaattcat caatgtacaa gggggcggaa gcggaactgg tttgtctcaa gtacagtcag
      361 gagcagtcga catcggaaac tctgatttgt ttgcggaaga aaaatcgggg atcgatgcct
      421 cagcattagt cgatcatcga gtagcagttg ttgggatcac tcctattgtg aacaaggata
      481 ttggcgtaaa agacatcagt atggaaaacc tgaaaaaact atttacaggc gagatcaaaa
      541 actggagtga agtcggtgga aaagatcagc cagtagttat attgaaccgc gcttcaggaa
      601 gcggaacccg tagcacgttt gaaaaatggg tattggacgg agaaacagct gttcaggcac
      661 aagaacaaga ttcaagcgga atggtgcgcc agatcgttgc cgacacaccc ggtgcaatca
      721 gctatgttgc tttttcttat gtttccgatg atgtagatac gttgaatgtt aacggtgtag
      781 aaccgacaga tgaaaatgtg acaacgaaca aatggacgat ttgggcatat gagcatatgt
      841 acacaagaga tcatccaaaa aaactgacaa aagaattttt agactatatc ttatctgatg
      901 aagtacaaga taacatcgtt ggagaactag gttatatccc tgtttctcat atgaaagtcg
      961 aacgtgattg gcaaggaaat atcgttaaag agtaatcttt acacaaaatt tacaaactta
     1021 gctaaacttt tacatgttat taaaaccaaa ttgatgttca atttgtacac tgagtgagta
     1081 tgttaaacct gattaagggg gagtcatctg tggaagatgt gaaaaaagta ttattaacaa
     1141 aatcaaaacg ttcaaaaatg gaacagcgtg gaaaattcat cagtttttta tgtatcgcgc
     1201 tgatcgtgtt ggttgtatta tctatttttt attttgtagc tagtaaagga ttggccacct
     1261 tttttactga taagatcaat gtatttgatt ttctgtttgg tacagattgg aatccaagcc
     1321 aaatcggagc aaatgggaaa ccaatggtag gggcattgcc tatgatcaca ggttcgttta
     1381 ttgtgacctt tttatctgct atcgttgcca cgccatttgc cattggtgca gcagtattca
     1441 tgacggagat ctctcctaaa aacggaacga agatcttaca gccggtcatc gagctgcttg
     1501 taggtattcc ttctgtcgtt tatggtttta tcggtttatc agttatcgtg ccttttgtca
     1561 gaagtatttt tggcgggaca gggtttggta tcttagctgg tacatttgtg ttgttcgtta
     1621 tgatcttgcc gactgtcaca acgatgactg ttgatgcatt aaaggcagtg ccacggcact
     1681 atcgggaagc ttcattagcg cttggtgcca caagatggca aacaatctac aaagtcgtgc
     1741 tacgagcagc cgtgcccggg attttaacag cagtcgtttt tggtatggct cgtgcgtttg
     1801 gtgaagcctt agctatccaa atggtcatcg gtaatgcagc attgatgcca acaggactta
     1861 ctactcctgc ttctacattg acgtccatct taacaatggg aatcggaaat acaatcatgg
     1921 gaacagttga aaataatgtg ttatggtcat tagcgctgat cttgctattg atgtcattat
     1981 tctttaatat cgtgatccgt atgattggga agaaaggaga gctgaaataa tgaacgcaaa
     2041 acgctcagat aaaattgcta caggtgtttt atatatagtt tcggggatca tcgtattgat
     2101 tttagcagct ttactacttt atatcttagt tcggggaata ccgcatattt catggtcctt
     2161 cttgaccgaa ccttccaaag cctaccaaga aggcggtgga atcgggatcc agctatttaa
     2221 ctcgatttat ttgcttttga tcacgatgat catcagtttt cctatttctt taggtgcggg
     2281 tatctatctt tcagaatatg ctggaaaaaa ctggctaaca gatgtgattc gcacgtcgat
     2341 tgaaatcttg agctcgttgc cttctgtcgt tgtcggttta ttcggtttct tggttttcgt
     2401 tattcaattc cagtatggtt tctcgattat ttctggtgca ttggctttga ctgtattcaa
     2461 cttgcctctt ttgactagaa cagttgagga gtctttacaa gcggtccatt acacacaacg
     2521 agaagcagga ttggccttag gtttgtcacg ctgggaaaca gtgataaaag tggtggttcc
     2581 agaagcgaca ccagggattt tgactggtgt gatcctaagt tctggaagaa tttttggtga
     2641 agcagctgca ttgatctata cggctggaca aagtgcacct gcgttagatt ttacgaactg
     2701 gaatccatta agtgtttcaa gcccgatcag cattttccgt caagctgaaa cattagctgt
     2761 ccatatttgg aagatcaata cagaaggcac gatgcctgat ggtgtttctg tttcggctgg
     2821 cgcttctgcc gtgttgatca ttgctgtttt actgttcaac ttcggcgctc gtgcgattgg
     2881 caaacgatta taccgaaaaa tgacttcagc ctaaggagaa gaagcaaaat gaaaaaatat
     2941 aactggaatg aaacaaatgt catcaccatg ccaaaagaga aagaagtagc actatatacg
     3001 gatgatctac atgtctggta tggcgacaat gaagcaatca aaggagtgga tctggaattt
     3061 gaaaaaaata agatcactgc actgattggt ccttccggct gcggaaaatc tacgtatctt
     3121 cgttcgttga atcgaatgaa tgatgggatc gctaatacga aaatcactgg gaaaatcatg
     3181 tatcaaggcg tagatattaa tgcgcctcaa gtggatgttt atgagatgcg caaacggatt
     3241 ggcatggttt ttcaacgtcc taatccgttc agcaagtcga tttatgacaa tattacattt
     3301 gctttgaaac agcacggcga aaaaaacaaa aagaaattag atgaaatcgt tgaaacaagc
     3361 ttgaaacaag ctgccttgtg ggaccaagta aaagacagct tggacaaaag tgccttggct
     3421 ttatctggcg ggcaacagca acgtttatgt attgctcgtg cgatcgcgat gaaacctgat
     3481 atcttgctgc tagacgagcc ggcaagtgct ttggacccta tttcgacagg aacggttgaa
     3541 gaaacacttg taaacttgaa agaagactat acgatcatca tcgtgacgca taacatgcaa
     3601 caagcagctc gtatcagcga ctatactgcc tttttctatc taggaaaagt aatggaatat
     3661 gacaaaacta acaagatatt taccagacca aaaattcagg caaccgaaga ttatgtgtcc
     3721 ggtcattttg gttaagacgg aggcctcaac atgacaaaag aaattatttc atctaaagat
     3781 cttcatctgt attatggaaa gaaagaagca ctaaaaggga tcaatctaag tttcaatcaa
     3841 ggggaaatca ctgcgatgat cggtccttct ggttgcggga aatccactta tctgcgttct
     3901 ttgaaccgga tgaatgacct gattccgaat gtaacgatca ccggaagtgt tttatataaa
     3961 gacaaagaca tctatggtcc aaaaacagat gttgttgaac taagaaaaga aatcggcatg
     4021 gtattccagc agccaaaccc atttcctttt tctatctatg aaaatgtcat ctatggattg
     4081 aaattaaaag gggaaaaaga taaaaaagtc cttgatcaag tagttgaaga aagcctgaag
     4141 gcagcgtctg tttgggatga tgtgaaagac aaattgcata aaagtgcttt atctttatcc
     4201 ggtgggcagc agcagcgtgt atgtatcgca cgtgttttgg cagttaatcc ggaaatcatc
     4261 ttattggatg aaccaacaag tgcgcttgat cctgtttcta ctgggaaaat cgaaagtatg
     4321 ctgttagaat taagagagcg gtatacgatg atcatcgtga cccataatat gtctcaagct
     4381 tcacgtattt cagataagac ggcattcttt ttagatggtc acttgatcga atacaacgat
     4441 acgaagaaga tattcatgaa tccagaaaaa caagagacag aagattatat ttcaggtcga
     4501 tttggataag gaggaaacgg aatgctacgt acacaatttg aagaagaatt gctgaatctc
     4561 cataatcagt tctacgaaat ggggatgatg gtgagcagcg ccgtgcacaa gtcagttcgt
     4621 gcatacatca aacacgataa aatcttagcc caagaagtta tcgaaaacga tataaatatc
     4681 aataacatgg aaacacgctt ggagaagaaa agttttgaaa tgatcgcatt gcaacagcca
     4741 gttacaactg atttgcgtat gatcattacg gtcatgaaag ctagctcgga tttagaacgt
     4801 atggccgatc atgcggtgtc tgttgctaaa tccacgattc gcgtaaaagg gcagacgaga
     4861 ataccggaaa tcgaaaaaga gatctccgat atgtccgatt atgtgaaaaa aatggtggac
     4921 aacgtcctag ttgcttatgt caaaacagac gaaaaagacg cacgtacgat cgccaatatg
     4981 gatcaaagag tcaatgacta tttcaatcga atctataatg caacaatcaa aaatatgcag
     5041 gaaaatcctg agacagtcat cagtggaaca gactacttga atgttgccag ttatctagaa
     5101 cggatcggag actatgtgac aaacatctgt gaatggatcg tctacttggc tacagggaaa
     5161 atcactgagt taaatacgaa ccacaatgag attttctaaa ctgaagctgt gattatgccg
     5221 tttgtttagg aaaagaggtt gtgaaatcag cggttgtgaa aaagctgttc tgcatcaagt
     5281 aataagaaca gtcaaacaaa aaatagctcc tcatattttt cgtttggctg gacttattac
     5341 cgcagatgca agcttttgaa caccgtttat tcgggaaagg gtttgtgaca aaacatgtca
     5401 caaacccttt tcatcatttc atagaaagga taaagaatgc aaaaaaaaat tagcatcatc
     5461 actatatttt ttatttgtgt gcttacttca tgggttattc agcatcaagc tgctttatat
     5521 gaagtacctg tcatcgagat cgaaaaagta cgaataaaag aggatcatca attgattaca
     5581 ggaagactga tgaacacgga tcaaaaagga gaatcgattt atttatcggt tccttatcaa
     5641 aaaaatcaaa tagaaacagc aaatataaaa gcgagacaaa tgtatctagt ccaaatgcat
     5701 ggagatgaat ggcagctagt agcaaaaaaa aaatgatggc tggcttttct tcttcacaag
     5761 tatctccatt ggcgccatgt tgcttattgg cggaaaacag ggtctatttg ctttaggaag
     5821 tctcatcatc aatatcgttt tacttttact tttgttgctc atctttacta aaacagaagg
     5881 gatttctcta ttaaatatat ctatcctgtt cgtcgttata gggatgatta ttagcatatt
     5941 ggctttagat ggatggaata gaagcagtat aatcaaaatt tcagctgcag ttacgagtgt
     6001 ttttttagca ttttttattt gtcttttgac aatgaatcat tggaaagacc aaggactgcg
     6061 ctatgaggaa ctgaattatc tgacacgacc gtatcgttct gtttttcttt ctagcgtact
     6121 gattggaaca gctggaggaa cactcgatac cgttatcaca gtcattgcga cattagaaga
     6181 attgactaag cgacaaccag aaataacagc gaaacagtta tggctttcag gaaggcaagt
     6241 gggtcgagat gtgattggct cgatgaccaa tatccttttg ttcgtctata tcagtgggtc
     6301 agttccatcg cttcttttat atttaggaaa tcaatggtcg ttcaaagaaa cgatagaaca
     6361 gcatttatca ttggaatttt tacgcgtcat tgctggcagc ttaggaatag tattatcgat
     6421 ccctatctcg gtcctctttt ttctgactgt aaggaggctg aaacgatgaa tgtacttatt
     6481 atacttgttg ggattttagc aatcagcgtg ctacttattg gcggtacgca aggtatgtat
     6541 attcttttag gcttattcat caatttaggg atctttttcc tgttgttatt cggttatcat
     6601 cagaagtggc cgatactggc attgtcggtc ataggatttt tattgattgc tgtggttatc
     6661 ttatttttta tcaacggtta taatctaaaa atgcgtgcag cttttgtgag tatactgatc
     6721 tttttatttt gtttcctact attgcttcct atcactgatt ttttagcgat ccaaggtttt
     6781 acatcggtag aactagaaga attatctggc ttagataaga ctttagcgat tgattttaga
     6841 ttacttacga gatcgttgct tctgattagt cttagtggtg ctgttttaga tgctagtgta
     6901 gcaatttcta gtgggacatt cgaagtatat caggcaaatc cgcaattatc tttttaccaa
     6961 ttgcgccatt ctagtttcgc tattgctaaa aaaatattgg cgtcaacagt aatgacactt
     7021 ctttttgcat tcatgggaag ttctttagcg ttgatcctct ggtttattga tttagacatt
     7081 ccttttcagc aagtgatcaa tgaaaaatca tttgttctag aatatacgat ggctattctt
     7141 accacattgt ctgcactact tgttcttcct ttaacctgcg tgactacagc atatctcttt
     7201 acaaaaaaga aagaacaact caagatggag taaaagttac aacttaagtc ctatgacatt
     7261 tttactgaat cagtgcataa tatggatgta aggaaaagct tgcaaacaat tttgcttaag
     7321 gaggcaattt ccatgaaaga aagagaacgt attttagatt tagtgaaaaa aggaatcctt
     7381 tcgactgaag aaggcttaga tttattagaa agcatggcaa ctgaaaaaga cgaaaagcaa
     7441 ataaaaaaag aagcagacaa ggtaactgct agtcataaag aaaaagatca ggcaagtcaa
     7501 ttgatcgata aacttgaaaa cggcgaagaa gaaatttctg agccagttga tccaaaggaa
     7561 agagaaaggc aagatcaaga aaacttagaa aagatcttag atgaactagc aactgaagcg
     7621 aataaaactt cggcgcgtct agatgaagta aatgctcaat tcgctgacaa taaggcagca
     7681 cgcaatgaga aacaggaagc attgatgcag ctgaatacaa aagaagaatt aggcgagttg
     7741 acagaagaag aattagcaca gcgtcagacg ttagaagcag aaatcaaaga attagaagct
     7801 agtggcgata cactgttaga agaacaattg aaattagaag cagaattaaa agatatccgt
     7861 aagaatcaat ggtctgagaa aaaagaaacg tttactgata agtttgaatt gccagatgat
     7921 tggaaagatc aagcaacaga tacactgaat caagtaggcg aaaaaatgtc agaagctgga
     7981 tcacagttag gcaaattctt gaagaaaaca ttccaaactg tttcagaaac agtgaatgac
     8041 aacatggaat ggaaagatgt cagcttacgt gtccctggga ttgcgacaac gaaatttgag
     8101 catgaatttt actatgaagc tcctgcagca agtatccttg atatcaaggc agcaaacgga
     8161 aacgtgacgt taaaaacgtg ggacagcaac gatgtgaaag ttgaagctaa gatcaaactt
     8221 tacggaaaaa tgggtgctga accatttgaa gcattctctg aacggagcca gattgaggtt
     8281 aatgaagatc atatctcctt ccaaattcca aataaacgtg tgcgtgcaga ccttgttttc
     8341 tacttaccta aacgagtata cgaccacgca gctattaaac ttctaaatgg caacatcatg
     8401 attgaaacat tggaagctaa agatatttat acaaaatcta cgaatggtaa catcatcgtg
     8461 gaccaattaa ctgcaacgat gctggaagta gaaggtgtaa acggcaatat cgatattcga
     8521 aacgggaaca tcttagattc tattatcgaa acagtaaatg gtacagtgac atttggtgcg
     8581 acagcagaaa acctttctgt gtctttggta aatggtgatg tacgtcttac gattaaagaa
     8641 gataatttga aaaaagtaga agcaagttca gtgaacggaa atgtcaaagt cgctttacca
     8701 gatggcatcg gtttggaagg acatgctaaa acaagtcttg gaagtatcaa cagccgtctg
     8761 tccaattacg aagtagttcg tgagaaaaaa gaacggacaa accaaatgtt gcaattccgt
     8821 cgtgtttcag atggtgaaat cacgcaagtg caactttcaa cgacaacagg aagtatctat
     8881 ttaaaagata cagataaata aagaggttgt gaaagagatg ttcagccttg agcaataaga
     8941 agcgattttg taaaatagct tcccctattt tacaaaattg tgccttattg ccgataggct
     9001 atctcttgaa caccgtttac caagagatta tgaacctgcc aattatcgcc gagtcacaag
     9061 gaataatttc agaaaaagct cgtcacgttt tatgaatatg gtaatttgtg accgagaatt
     9121 ttgcagaaag acaccgatta agaagaaggt tgtcacaacg attttcttca tttaaaatag
     9181 tagaacagag gtgagacatg atgaaaaaaa agttgacaaa atccaataaa aatgttgttt
     9241 tgacagggac tttagcagga ataggagaat acatcgggat tgatccgact gttatccgtg
     9301 tgctttatgt attcctgagc ttagttgctt ttggaagtcc aatcatttta tacattttat
     9361 tagctttgat tatcccatct gcgcgttctg cacgaacaaa ctatggacat aacaatgcat
     9421 attatgaaaa aaacaattat cgtgaacaaa ctcgtgaaca aacaaaaaaa cgcaaagaag
     9481 cggaaaaaat cgatgatgac gaatggagtg acttttaatg tcgtactttc aacgtatttt
     9541 agttaatacg ttaacattca tatcattggc tgttcttttt cctgcgatgg tccatgtgag
     9601 cagtatttgg acggccgttc ttgccagctt cgtattgtct gtgttgaata tgtttgtcaa
     9661 accgattttg acgatactgt ccctgccctt tacattagtc acattgggat tgtttacgtt
     9721 tgttatcaat gcagcgattc ttaaaatgac ctcctttttt gtgggagcag aacattttag
     9781 tttttcttca ttcggtgcag cgttgttagt agctatcttg atgtcgcttg tcaatgtaat
     9841 tgtcagtgaa cataacagta gaaaataaaa gaaagctgtg ccgaactatc ggcgcagttt
     9901 ttttatttag aatcaggaat gcgttttcta ttacattggt aattaaataa aaacgttttt
     9961 tttaattggt agtacttttg gctagacaat gataaaatga tagagaacac tctaatagaa
    10021 atgaggtagc atgaatgtca gaagttgtaa aagttagcca attagtgaaa aaattatctt
    10081 tggaaatcgt gacaggcgac gagaaaagct tagaccgtgt catcgtaact ggggacatct
    10141 cacgcccagg actagagttg actggttatt ttaattatta ttcccataat cgtttacagc
    10201 tatttggcag taaagaaatc agttttgcgg aacggatgat cccagaagag cgtttgatca
    10261 tcatgagaag attatgtagt gaagatatgc ccgcatttat tatttcaaga ggattaccgg
    10321 ctccagaaga aatgatccag gcagcaaatg aaaatgggat agctgtactg cgttctccca
    10381 tctcaacttc tcgtttatta ggagaattat ccagttattt agatggtcgc cttgcccctc
    10441 gaacaagtgt ccacggtgtt ttagtggatg tttacggatt aggtgtactg attcaaggtg
    10501 acagtgggat aggaaaaagt gaaacagcgt tggagttgat caaacgcggt catcgattga
    10561 tcgcagacga tcgagtagat gtttatcagc aagatgaatt aacggtgatc ggagaaccgc
    10621 ctaaaatcct ggaacatcta attgaaatcc gaggaatcgg gatcattgat gtaatgaatc
    10681 tttttggtgc gagtgcggta cgtggctcta tgcaagtcca gttggctgtt tatctggaag
    10741 catgggcaaa agataagaaa tacgaccgtc tgggctctga agacacgacc gttgaaatcg
    10801 cggaagtggg cattccacaa ataaaaatcc ctgtcaaaac aggacgaaac gttgcaatca
    10861 tcattgaagt agccgcgatg aatttccgtg cacgtacaat gggctttgac gcaacgaaaa
    10921 catttgaaga aagattaagt cgcttgattg aagaaaactc aggcaacgac tagcaaggag
    10981 tgacaatatg ttagcacaaa tcaatcgagt tgcttttgag cttgtaggga ttcctatcta
    11041 ctggtatgca ttgatcatcg tatcaggtat cattatcgcc atgtggctta gcagcagaga
    11101 ggctgttcgg gtaggattaa aagcagatga tgtgacagat tttatgttgt ggggattgcc
    11161 tatctccatt attggtgctc gcttatatta tgttttattt gatcttcccc agtatatagc
    11221 tgatccaatc caaatattca atatccgttc aggaggctta gctatttatg gcggactgat
    11281 tgcaggcgcg atcacgctgt atttttttac taaatatcat tttatttctt tgtggacttt
    11341 tttagatatc gctgcaccaa gtgtattatt agcacaggca atcggtcgtt ggggaaattt
    11401 catgaaccac gaagcatatg gaccagacac gacgcgaagc ttcttagaaa gtctgcattt
    11461 accgcaattc atcattgata atatgtatat cgaagggatc tatcgtcaac caacatttct
    11521 ttatgaatca ctttggagtt tgattggatt tattttgctt ttgtttttac gaaagaaacc
    11581 acaccttttg aaaaaaggcg aagtcctttt atgttatcta atgtggtata gtttcgggcg
    11641 tttctttatt gaaggattac gtacagacag tctttacttt ttaggtgtga tccgtatttc
    11701 tcaattatta tctgctgtgt tatttgtcgg tacattgatt ctatttattt ggcgcagaaa
    11761 aaaaggaaat ttaccggatt atgaccgctc attaggaaaa aatcaacaaa ttatctgatt
    11821 tttagagcgt taaaaatgaa aaaaatttca ggagtggtaa aatgaattat agagtagcgg
    11881 ttttaggacc aggctcttgg ggtactgctt tggcacaagt cctcgccgaa aacggacatg
    11941 acgttcggat ttggggacat cgtgcttcac aagtagaaga aatcaacacc caacacacga
    12001 atcaacgtta tttaccagat cattatctac ccgattccat ccaagcattc accaatatgg
    12061 aagatgcagt aaaagacgca gatgcggtgc tattcgtcat tccaacgaaa gcaatacgtt
    12121 ctgttgcaaa agaactagtg cctaaattga atacaaagcc agtgatcatc catgcaagta
    12181 aaggattaga acagggaaca cataaaagga tctctgacat cttgttagag gaaatcccag
    12241 cagaaaaaag aaaagctgtt gttgttcttt ctggaccaag ccatgcagaa gaagtagcga
    12301 aacatgacat cactacgatc acagctgcaa gtacagatgc aaaagcagca aaatatgtac
    12361 aagagctgtt catgaataat tattttcgga tctataccaa tcctgatgtg atcggtgtag
    12421 agatgggggc agctttgaaa aatattattg ctattggtgc tggcgctatt cacggcttag
    12481 ggtttggcga taatgcaaag gcagcaatca tgacgcgcgg attagctgag atcagccgtt
    12541 taggtgtagc aatgggtgcc aacccgctga cctttatcgg attaagcgga gtaggcgatc
    12601 tagtcgttac ttgcacaagt gttcattcta ggaactggcg cgcaggcaac ttgttaggac
    12661 aagggcagcc cctagaagag gtgctagcca atatgggaat ggtcgttgaa ggtgtgaata
    12721 ctactcaagc agcgatggaa ctagcccaaa taatggaaat cgaaatgccc atcactcaaa
    12781 caatctatga agtgctgtat gaacaaaaag aaatcaaaac agccgcaaaa gaaatcatgt
    12841 tacgtgatgg gaaaaaagaa aatgaattct cattaacaat tttttgaagg agcgaatgta
    12901 tatgaaagtc aaaaaagcag ttattccagc ggcaggatta ggaacaagat ttttaccagc
    12961 aacaaaagct atggcaaagg aaatgttgcc aattgttgat aaaccaacaa tccagttcat
    13021 cgttgaagaa gcgttgaaat caggaatcga agacatcttg atcgttacag gaaaagctaa
    13081 acgaccaatc gaagatcact ttgattcaaa tattgaatta gaaacaaacc taagtgaaaa
    13141 aggaaagacc gaattattga aattagtaga agaaacgaca gatgtcaact tgcatttcat
    13201 ccgtcaatct catccaaagg gtttaggaca tgccgttctt caagcaagag cctttattgg
    13261 aaatgaaccg tttgtcgtta tgctaggcga tgatatcatg gaagatgaag taccattgac
    13321 acagcaatta atcgatgatt acgaacgtac tcatgcttct acgatcgccg ttatgcaagt
    13381 tcctcatgat gaaacttcaa aatacggaat tatcaatcca ggagaagtat tggaagatgg
    13441 gttatacaat gtcaaaaact ttgttgaaaa accagatcca agcaaagcac caagtgattt
    13501 agctattatt ggacgttact tattgactcc agaaattttt gatgtattgt ccgagcaaca
    13561 accaggagcc ggaaatgaaa tccaactaac tgacgcaatc gatacattga ataaaacaca
    13621 acgcgtattt gcccgtaaat tcacaggtaa acgttacgat gtcggtgaca aatttggttt
    13681 tatgaaaaca agtattgaat atggtctaac acatccagaa gtaggtgcac ctttacgtga
    13741 gtatatcctg tctttaggta aaaaattaga agcagaagga agcaagatcg atcataatcc
    13801 aaaaggaata acagaaatca aagaagaaaa gaaaaaataa cccttttttc taacgagctt
    13861 cagctgctaa ttgaataaaa agtagttgaa gctcgttttt atttgtttaa aaaacacgaa
    13921 aatgctatcc ttatagaaaa gagagacaag aagggagttt gatcatgtca ggaggagaaa
    13981 ttgcaggatt gatcgcagca atcgcctttg cgatacttgt cgtttttatc gttcgtgtgt
    14041 tgttgcaagt ttctaaaact ttagaaaaag tagatcagac tgtagcagaa gcaaatacga
    14101 cgatcgaaat cgtcacaaaa gacgtagatc ttttgtctag acaagtagaa ggcttgctgg
    14161 tcaaaagtaa tgaactgctc ttggatatca atggaaaagt cgcaacgatc gatccattgt
    14221 tcacagcagt tgctgattta agtgaaagtg tatcagaact taatcattct agtaaaaaca
    14281 tcgcgacgaa agtcggcgga atcggtaaaa cgacagctaa agcgacggtt gccggaaaag
    14341 tcggtgggac agcgatgaaa ttttttaaaa acaaaaaaca tactgaaacg acaggaggaa
    14401 aataaaaatg gctaaaaaag gtggattttt attaggtgca gtagtcggag gaacagccgc
    14461 agcaatcgcc gcgttattgt tagcaccaaa atctggtaaa gaacttcggg atgaattagc
    14521 tgcccaagcg gatgatttga tggatatggc ttcagattac acagatatgg cgaaagaaaa
    14581 atcgactgag ttaacaggta ttgcaaaaga aaaagcgcaa gatctttctc aacaagcagg
    14641 tgatctagca ggtagtgtca aacaaaaagt aagtgaatca gcagatgaag caggaagtga
    14701 atctgacgat atcttgttaa atcttaaaga acaatcagct gacttatcta atcgtttcaa
    14761 aaaaacggca gaagatatga aaaaacctgc agatgaatta ggaagtattg ctaaagatac
    14821 ttcagaagat atcatgattg atgtaaaaga cgctgctggt aaagcaggag atactgtcaa
    14881 tgaaggaatg tcagaagcaa aaccagttgc agatgacaca aaagaaatga tgaaaatggc
    14941 aaaagaagat gcgaaagaag ctaaaaaaga aataaaagat acaatgacag attcatctac
    15001 aaatcactaa aatcactaaa atcacaaatt tatagaataa aaaggtggga gcggactagc
    15061 tctcaccttt tttactctta tttttctaaa actagtaatt cttttggtgt agtcgtgaat
    15121 ggcacacagc catcgcttgt cacatataca cagtcttcga tacgtacccc tactttttca
    15181 ggaatataga ttcctggttc aagagagaag cacatccctt cttcgattac taagtcattt
    15241 ccttctacaa gggaagggaa ttcgtggacg gttgttccga tcccgtgacc taaacggtga
    15301 ttgaaatatt cgccgtagcc atagctgttg atcacgtttc gtgcgatttg atcaagttca
    15361 cctgctgtca cacctggacg gacggcttct tgtgcggcaa gctgtgcttc aagagtgatg
    15421 ttgtatattt tttcttggaa gtcggttggt ttttgataag caattgtacg agtagcatca
    15481 ctgcaatagc cattccaaac aacgccaaga tcgaataaca caagttcatt cggtgaaatc
    15541 ttcgtgtttc ctggtgtacc atgagggctt gcagcatttg ctcctgcaag gactaatgtg
    15601 tcgaaagaca tttgtgaaac accttgtttt ttcaattggt attcgatttc tgcaatgatc
    15661 gcttgttcag tcacgccttc tttcactgct ttaaagccaa tctcaaatgc aacatcggcc
    15721 catttaccag cttcgatcag tttgtctttt tcctctagag ttttgatcag ttgtagacgt
    15781 tggatgatgg aagctagatc agtgtaagaa tccgttcccg tcaagatatc agagatagca
    15841 tcgaagcgct cgacagtcaa ggcgttcttt tcaatcccta cattgccagg ctgaccatag
    15901 cgagcacgaa gttcttttcc gatgatctcc caagggtttt cgctgtctaa atagccacgg
    15961 acatcatacg cccaactact gttttgagca tcttcaactt ccaaagcagg agtgaaaagg
    16021 aaaggatctt gttcaagagg gataaaaaga gctagtacac gctcatgagg atcactttcg
    16081 tatccggaaa agtaagcgat gtggccaggg tcgctgatat aagccaattc gacttggtgt
    16141 tgtgccatcc attgacgtag ttcattgatt tttacgttat tcatttggca acctactttc
    16201 taaattaatt ttgtattcaa taattgtacc actgatttat taaaagacca acgttctaaa
    16261 aactgaaaaa agtaaaaatt ttcatgaaaa cagagataaa acggttgcaa ttcttgagat
    16321 tatttgatat tctattttag aaatgtaaga cgtattttca gaaaacatat aaaatatgaa
    16381 taggagaaca caaatggaaa agcaaacaat cactatctat gatgtagcga gagaggcaaa
    16441 tgtttcgatg gctactgttt cacgtgtcgt aaatggcaat ccaaacgtca aaccagcaac
    16501 aagaaaaaaa gtcttggaag ttatcgatcg cttggattat cgtccaaacg cagttgcgcg
    16561 tggcttggca agtaagaaaa caacaacagt tggggtaatc atccctgatg tcagcaatat
    16621 gttctttgct tctttagcac gtggtatcga tgatgtggca acaatgtaca aatacaatat
    16681 tatcttagca aattcagatg gtaacgacca aaaagaagtc aatgtattga ataacttact
    16741 ggctaagcaa gtggacggcg tgatcttcat gggtcaccat atcacagacg aaatccgtgg
    16801 agaattttca cgttcaaaaa ctcctgttgt attagctggc tctattgatc cagatgaaca
    16861 agtaggtagc gtaaacattg attatgtatc agcaacaaaa gatgcagtaa acaaattggc
    16921 aaaaagcggc aataaaaaaa tcgcttttgt cagtggtgcg ttgatcgatc ctatcaatgg
    16981 acaaaatcgt ctgaaaggct ataaagaagc attaagcgaa aataacctac catatagcga
    17041 aggattgatc tttgaagcac aatacaactt caaagatggt ctatctctag tcgatcggat
    17101 ccataatagc ggtgcaacag ctgtctatgt ttcagatgat gaattagcca tcggtatttt
    17161 ggatggttta ttagaccgtg gcgtgaaagt accggaagaa ttcgaaatca tcacaagtaa
    17221 caattcacta ctgacagaag tagctcgtcc tcgtttaaca agtatcacac aaccattata
    17281 cgatttaggg gcggtatcta tgcgcctatt gacgaaaatg atgaataaag aagaagtcga
    17341 agaaaaaacg attatcttgc cttatggaat cgaagaaaaa ggatctacaa aataataaaa
    17401 ggacaaccat tcagaggttg tgagcctgcc gtttaactct gcgttacaag gagcaatttc
    17461 aaaaaacagc atttcatgtt tgatgaatat tgtgactcgt gattcggagt tggcaggaga
    17521 acaccgttta ttcgggaaaa ggggttatga caaaattttg tttaatcctt tttttttgtc
    17581 ttaaaaaaga gagaaagtgg ttgaaattac atttatcgta tataaaacaa tccgtgtata
    17641 gatgctgcat tatgttcacc accatcaaaa aaataaggga ctgtgacaat actattgtca
    17701 cagtccctta ttactgtgta ttctattaaa tcaatcatct ttctcatctg attctttggt
    17761 tgcttgattc gctcttgcat aagctgaagc ggtgttccag taatctgtat agttttcatc
    17821 ggtaccgcca acgccaaatt taaaggcgct tttcttcggt ccatttttcg cccatagcga
    17881 ttcaactgtt tttcctggtg tttggatgga ttttttattg acagtaactt ttccaggtgt
    17941 ttgaccagta aatccagata cttttttctt catcacatca gatgataatt cgaatttctc
    18001 atcagtgcca aaaatgtcag gttttgcttg gtaagcttga ttgatcagat tggcaagata
    18061 attagccgaa cgtatccttg ctttgctgtc cattccagta ttgtcatcgt gccctgccca
    18121 gctactgatg gtaatagacg gagtagagac aattagccat gaatctcggt attcattggt
    18181 agaaccagtt tttccgaccc aatctgcttt tcctagattt ccgtttaagc ttgagatggc
    18241 atctttgaat ggtgtagtga tttttgcatt gatcacactg cgcatcatgt cattcatgat
    18301 cgatgccgtt gcttccgaat agatccggac agagttgctt tcgtgtttat aaattacatt
    18361 tcctgcgtta tctgtgatgg aatcgatgat atagccttct tcatagacgc cgccgtttgc
    18421 taaagcctga aatccattgg tctgttgaag cgtcgtgaca tctactgtac ctaaaggagc
    18481 agattcaacg ccccaattgt catttgccgg gtagttcatc tttgccaagt agtgctcgta
    18541 agcatattgt ttcgatccac cggaattcaa cacatcttga tataagtgat aagccgggat
    18601 attgttggac cattctagtg actcacggac ggtttggaag gtgttcgatc cttcgttagt
    18661 agcattgacg attttctcgc cagcattttc tccttcttgc caagttgttg cataatctga
    18721 tacacgggat tctgatccga taagccccat gtcgattgca ggtccataaa caagaactgg
    18781 tttgattgat gagccagctt gacgttctgt atcgaaggca tggttatttt gattctgact
    18841 gtaattccgt ccgccaacga atccgtagat gcggccagtt ctgttatcca tcaatacatt
    18901 tccggtttct acttgactgc cagcaccatc atctaacatg tatccataat tttctacgcc
    18961 attttgcaat gcagcataga catctttatc gattgtcgaa tggattgtat atcctttatt
    19021 ttggatcgtt tgctgtgcct tttgataata agcgtcactg accgatgaat cagacatatc
    19081 agcgttgtct ttttcagcca attgttgtgc aatgattctt gttgcttcat tcatcacagt
    19141 ataatacaag aattctctgt cagtctgttc tgcgatttgt tgtggtagaa agtcttttgt
    19201 aaggtcatag gcttttgctt cttcgtattg ttctttcgta atttggcctt cacgatacat
    19261 actgaataaa acaaaatctt ttctggcaag gccggcagaa agatcttctt ttagcgcacc
    19321 tgtgttcgtg tatggactat acgtgatcgg gctttggggt aatccagcga tataagcagc
    19381 ttgcggcagc gtcacatctt ttgcatctac accaaagatt cctcttgcag cttcctggac
    19441 tccagcaatg ttttgtccct tattattacg accaaatggt gagacattca aatacgtagc
    19501 aatgatctca tcttttgaaa agtatttttc tacttgtgca gaaagaatga tctcgtttgc
    19561 tttacgtttg aatgttgttt catctgtaag gatctgctgt ttgactaatt gctgtgtcaa
    19621 agttgatcca ccagaagagc caataccagt agcttcagat actaatgctc gtaaaacagc
    19681 tttaggaacg taaccttggt gtttatcgaa gtattcatcc tctgtgctga taattgcagt
    19741 tttcaataaa ggtgaaattt tatcagatga aatagtcgtg cgcatcagat ctgtctggat
    19801 ttttgatatc tctgtattat ctgcataaac aatctttgac gtttctgtaa tgtttcctag
    19861 ttctgtctgc agtgcttttt tagtcggcaa ttgtgtgtct tcgacgagat aggcaaaata
    19921 gccagcgcct attccaatac ctagagctgc gaacatcaaa agaagaacag taataaaaac
    19981 agtcaatgat tgaaaaactc taaaaataat cttaggaaca aaccattttt ctttttttct
    20041 tctattctgt ttttttcgag tatttttgcg tggcaaaagg gtcacctcaa ctaatggttt
    20101 tatttcgcta attatagcaa ataatagaac aaaaaaacag acaaggctgt ttttggcagg
    20161 aatttctttt ttaaaagagt taaaacgtga gaaaatgatc ttttttataa aagagttctt
    20221 aagcttttct ttagagaaaa tttcagttac tatggagaac agggcaaaga aaaatcaatc
    20281 attttctttg tatatcatct taccaatata taggaattgt tagtaacaat tgcctttcaa
    20341 ggaggaatcc atccatgtta ttaggctcac acgtcagcat gagcggaaag aaaatgctgt
    20401 taggagcagc agaagaagca gccagttatg gatcttcgac ttttatgatc tatacaggcg
    20461 cccctcaaaa cactagaaga aaagccatcg aagagatgaa tattgatgcc ggaaaagcgt
    20521 acatggcaga aaacggtcta acaaatatcg tcgttcatgc cccttatatc attaatttgg
    20581 ggaatacgat caaaccagaa atgtttcctt ttgccgtcca atttctgaga gaagagattg
    20641 ttcgtgcgga agctttaggc gctactcaaa ttacacttca cccaggtgct catgtagggg
    20701 caggaacaga agccggaatt gctagaatta ttgaaggctt gaatgaagtt ttgacaaaag
    20761 aacagacggc acaaatcgct ttggagacaa tggcaggtaa aggtacggaa atcggtcgaa
    20821 catttgagga attagcgcaa atcatcgatg gagtaaaatt gaatgaaaaa ttatccgtta
    20881 cttttgacac ctgtcatacg aatgatgccg gttataatat taaagaagac ttttcaggtg
    20941 taatggaaga gtttgataag atcatcgggt tagatcggct taaagtactc catatcaatg
    21001 attctaaaaa tccgcaaggt tcgcataaag accggcacgc caatattggt tttggaacaa
    21061 tcggattcga cacgctgaat aagatcgtcc atgatccaat gtttgacaat atttcgaaaa
    21121 tcttggaaac tccctatgtc ggcaaagata aaaagaaagc ttacgcacca tatggaaaag
    21181 aaatcgccat gttcaaagca caaatattcg atccagaagt gtttcctgag ttattagcag
    21241 aagaagtgat actctaagat tttctatctg acagcagcaa aaaaggacca ggcacattgc
    21301 cttgtccttt tttgtttaag aaacaaagga gtgctttttg cagtcttttt catcatgcat
    21361 cttctccccc ctctttttaa atttagacaa acagggtata ctggtagaaa agtaaaaaaa
    21421 cgaaaagttt cacaagcaag tggcaaaacg tgattggaag gacgaaaaga tgctgaacac
    21481 tttaaaaccc ttgatcaacc aactaaaaaa gaaacataca tactttattc ttggcatagc
    21541 cctattattt acaattattc gtttgtattt atatagtaaa gcaatctatg gaacagacat
    21601 gtcggcaacc tatgatgacc agctgctgat tcgctatgct caaaatattt tggacggtaa
    21661 atggctaggg gagtatacga ctacaacact ttccaaagga atctcctaca gcttattttt
    21721 agtacttgca cataaactgc atctttctta tgcagttttg ttcggcatgt tcagtatttt
    21781 tgccagtata ttggttgcac tcgcgtttaa accgatcgtg aagaacaagt atcttctttt
    21841 aagtttctat ttttattttt tgttttctcc gattagtttt acacatgaat attccactcg
    21901 aacgtatcgt aatgccctcg tgattccggc tgttgagatc attatcgctt gtttactagc
    21961 tatttattac cgtaaatata gttccagcaa aaaaatgctg ccgtggtttt tagggctagc
    22021 tgtttctttt cctttctttt ggttcattcg cgaagattcc atctggcttc ttccttttac
    22081 tgtagtcgcg ttaggcatca gtttcgtcca gatcttgcta ggacaagact tttctttcaa
    22141 agaagcaaag aagttaaaag aacgaccatt tctcctttcg aaacaagaat ggctgaaact
    22201 ttcattgttt ttactccctc tagtcggttt ctccatcgtc tatcagtgga tcgaatataa
    22261 aaacgagaca acatatagta ttgccgccat caatgaccgt tcgagtggcg aatttggacg
    22321 tttgatgaaa cagctgatcc gaatagatga cgaaacgaac ttaaataaag aaaacagtga
    22381 gatatgggtc tcgcatgctg cattaaataa agcattagac gcatctccta catttcatgc
    22441 tgtttctact cgtattgacg aattgtatac gactcatgcg tggacccaag gtggaaaagt
    22501 aaaagaatta ccaggagata tcattttttg ggcattgcga gatgtggtaa gcgaatctgg
    22561 ttattaccaa aacaatgcaa aagaaaccaa tgatttttgg aaaaaagtca atcaagaatt
    22621 agaagaagcc tatcaaaagg gaactatcaa aaagaaaaaa gaattctatc tgatgggatc
    22681 aggggatgga aagacgatga atgatctgcc aatcgtattt gcttttctga aatcaggata
    22741 tgcctatgca tggcgataca aagatttcca tcaagggggg aattatagtt tcggtacgca
    22801 agaacaagtc gaacaggccc aagaattatt gaatcttcca ctaatggata attggatcga
    22861 tagcagtgat ccgagaacac ctgatttcca gttgacaaaa acagcaaaag tcgcgaatgt
    22921 catgataaaa atttaccaag ttctggccat tcccgtgctg attgcttcaa tagcagggat
    22981 attacttatg atactaggaa ccgcatttgc aaaagctgat cgtgcctatt atagttcctc
    23041 tttgattgta gtcaccggat taatactgac acaattggtt tttcttttcg gcgtctcgtg
    23101 gttttgttct tatgcgccag aaaaaaagga ttatttttta agtgtctaca ctggcgcagg
    23161 cgtgccatta acgcaattca tcgtagtaac aagcatgcta gttttcagta aattgaatct
    23221 gaaaaaagct ttatcttcca aataaaaaca tactaagatt agaggagaac atcattgacg
    23281 aatgatgttc tcctctattt tctattttta gattatagtg aagagtgaaa gaaagttcga
    23341 acaaagcctt gaggactatg agtccctatc aaaaaccgaa cttctttact gtcattttag
    23401 aatcaggttt acgtatgttg gggccatgag cccgtgtata ggaaattgga atcgaaatga
    23461 agcagtaaag ttctttcaaa acttaaaaag gaggaaaaca aatgccttac attcttgcat
    23521 tagatgtttc aatgggacac agctacagtg tcctatacaa agacgacacc tgcttatttg
    23581 aagacgagat cgaacacact caaagaggat ttcatgcatt actcgaagag atccagcact
    23641 tgcctgaacg tccattgatt gtttttgaag caacggggat ttattccaga ccagtcgaaa
    23701 agttctttca agatcatcac ttttcttact gtttgttaaa cccgttagaa gcgaaaaaac
    23761 agatggaaga aaacacctta tgcagttgga aaacagataa atcggatgcc catcggctcg
    23821 cacagactca tcttaaaaat caacgtcagc caaaagaagt acaaagcaat ttttacttag
    23881 agatgcgcga tttagcccgt ttttatcaag aaattgagaa gaaaatcact cgtctgcgca
    23941 tggatttaca caactgcctt cagttgactt ttccagagct tgaacagttc tttttaaaca
    24001 ggctgacccc ttacgcattg atattgatcc gtctttttcc ccatccagat tttgtattgg
    24061 catctactcg gacaaaaata aaaaataaac tgatcaacga aacacggaaa aaaatctccg
    24121 cgaatcgtgc cgagcaaaag gcagatcaaa tcatccacta tgcacagtgt gcctatccag
    24181 ctgttgaaaa agacagtatc cactgtcaaa aaacgatcta ttacgctgaa cttctccaag
    24241 atttactcga acaaaaa
//
LOCUS       DADGKS010000039        23895 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.039, whole genome shotgun sequence.
ACCESSION   DADGKS010000039 DADGKS010000000
VERSION     DADGKS010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23895
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.039"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..148
                     /locus_tag="JXV47_001672"
     CDS             <1..148
                     /locus_tag="JXV47_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type I restriction endonuclease subunit S"
                     /protein_id="HAX1487723.1"
                     /translation="KAIINSKDYEGYKAKHPEAKPFKYPQEMKRAWRKMLDDELIPLE
                     NELR"
     gene            complement(897..1510)
                     /locus_tag="JXV47_001673"
                     /pseudo
     CDS             complement(897..1510)
                     /locus_tag="JXV47_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406632.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(2731..3435)
                     /locus_tag="JXV47_001674"
     CDS             complement(2731..3435)
                     /locus_tag="JXV47_001674"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012610.1,HMM:NF019322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAX1487724.1"
                     /translation="MIFDKVKEQIRKVYITTDRKSELLPSERDLAQEFSVSRPTIRKA
                     LASLEDEGIISKNEGRGYLVKPASEKYVDHELDSFIGFFQDAVQQGKKISSKIIQQTI
                     IPADSTISECLEIEQNTLVLVLERIRYIDDYPTCIAKSCIPLSVLPEIVEHDFAKESL
                     FSVLESRGIRLAYAKRSIEVTPPTDLENLYLDLEKNEPVFVFTSIGFAKNQKPFEYEI
                     SKYPAYKTKFESTVSK"
     gene            complement(3450..4319)
                     /locus_tag="JXV47_001675"
     CDS             complement(3450..4319)
                     /locus_tag="JXV47_001675"
                     /inference="COORDINATES: protein motif:HMM:NF012585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487725.1"
                     /translation="MKIAVICSGGDSPGMNSALLAIKKTIDSEPDSEVVFFKNGYAGI
                     FKECIASVSLKEVEVFKAGTLIGTARFEKMRDLESRKIIIENLNKMEIDNLIVIGGNG
                     SLKGAELLKNESELQVSVIPGTIDNDFPNTDYTLGFDSALNTIIRSIDDLTSTANAHD
                     RIIIMEVMGRGCFALPEYASIANNTYWVERDDKEYLHLICKKFESEFYSPILLLPEGI
                     SNKQKIIEFITKNLPKETKYLNLAYLQRGSSPTFYDRYIGYLWGQLAAKELIEGKSGI
                     LSQKNGNIMLIPW"
     gene            complement(4427..5443)
                     /locus_tag="JXV47_001676"
     CDS             complement(4427..5443)
                     /locus_tag="JXV47_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003526912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAX1487726.1"
                     /translation="MFNFDQERFLKTQAGAVATNEQISNILESIASDLEEIYFIGSGG
                     VGILFDSTIEFARTRSTFPFHRVIAAEFMIHPNKTFSNKSLVVIPSLSGTTKETLELV
                     EYCNEMNVKTLALVGSPKTPLEKAATYSIYNDVLDDTSSENYYLQGLLIALFLMKQRN
                     EIDINQYNTYIEDLKKIPEALVHAKEQAEPMAKSFAKKHKDTSYHILTGAGDSFAEAY
                     YYGMCILEEMQWIKTRPVHAADFFHGTLELIEAGVSVIITEGEDDSRPLTERVKNFVP
                     KFTDVHVTVDTKDYDLPGISEDTRKIISPVVLATVFERISAFLEEERNHPLTTRRYYK
                     QMEY"
     gene            5633..8356
                     /locus_tag="JXV47_001677"
     CDS             5633..8356
                     /locus_tag="JXV47_001677"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012385.1,HMM:NF013070.1,HMM:NF015567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAX1487727.1"
                     /translation="MKTKILKELNDLLNSYDFPQYFPEECNAQYIAQKFQIKRNTASK
                     HLNELMEQKKVVKINGRPVLFFPVHTIERYISHSLDSFEFSSIDSFREKISKKKADHF
                     FDDLIGAKQSLKEAVQQGISAMKYPGGLPIMYFGSSGVGKSYLVEKLAEYCRQTGIIH
                     ENAPFIELNCAQYFNNPELLTSQLFGHMKGSFTGADSDHIGIIEAADGGIVFLDEIHR
                     LPPEGQEKLFIHMDKGVFRRVGDSGPWRLSHVRYIFATTEQEENFFLETFRRRIPIVC
                     TLPNYQDREISERKEIVFHLLEKESTLINKEILVSEAALSFLIRLDLYGNIGELDGLI
                     KQTIANKLFSGSNKKYIEIHISDLPSRYLLTENIELKNQIASQRFYIFSNGNYVHDCD
                     ETSTVTTNLRGLIHRVSKYYSECHDVNRNSEEFRRFVKDQMAEFNDRFIYQKNSEVLV
                     KYYLPEIQNIVQKISPSLFVHLSGNTVQAIATYLAIRDQWGYGKENASANEIEKLYEN
                     LKCNYLTDLNVFLLIFENALDTTLTIWDKLYISLCVISETGNEAKDINAIILAHGYAT
                     ASSIANVANRLVNQFVIDSIDMPLDISFSEVIDRLLHYIEYRKPKDGLVIFVDMGSLA
                     QIKTEIEQVIEVPTMIINNVTTEMAIETAQLIQSTSDIQKVVKKLPYSQFEKQVLYPI
                     KIRKRTIVVSCNTGLGTSIKIKEMMENNLSKDLGIEFLPYENETLRDTQQLEFLIKTK
                     DIIAIIGTDDPRVSNIPYISLEELFDGEIGKLYKVLLRVYGKEIAEAINQNIVKNSSL
                     NRLIDSLTILDAEKVVNQIEESLKDYQMRVGKTLSSLSKINLYVHISCMIERLIRNQG
                     VSSYPAIDQFLKRYETEVASIQKALSKIEKLYNIKIPMEEIAYVCNIIVSY"
     gene            8484..8906
                     /locus_tag="JXV47_001678"
     CDS             8484..8906
                     /locus_tag="JXV47_001678"
                     /inference="COORDINATES: protein motif:HMM:NF015567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose IIA subunit"
                     /protein_id="HAX1487728.1"
                     /translation="MRQILCMSHGPLAKGMIETLSIIVGDLDNIDFRCAYVDGNNDVE
                     MIIDDYLKESMGNETIVVTDIFGGSINNEWLRRLPDLSKVYLISGMNLSLLVDLYLKF
                     QLVSSDQIEEIIDHAIQASSGSIKFCNQLDYEQTVDDF"
     gene            8924..9394
                     /locus_tag="JXV47_001679"
     CDS             8924..9394
                     /locus_tag="JXV47_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAX1487729.1"
                     /translation="MIKLVRIDHRLIHGQVALTWTNAISADCILVANDEILNDPIQKT
                     TLKLAAPHNVKVVIKSIQDSIDAINSGKTDKYKLFVVTKTISDAKRLANGVEQIKSVN
                     IGSVKETSGSSALTHTIFVTEEERAELKGMVSEGIEVFAQQVPTDKAIDLKKSL"
     gene            9418..10200
                     /locus_tag="JXV47_001680"
     CDS             9418..10200
                     /locus_tag="JXV47_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008724498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1487730.1"
                     /translation="MDSLLVQAILLGLLTAFIVIDWMTGTNNLSRPIVSSVFVGLIMG
                     DLKMGIMMGATLELAFIGAITIGAARPPDTVSGGILGTAFAIATGKGAEFALTLAFPI
                     AALFLLVDNLLTLLVLPMIARKADRYAEKGELKNVSKMHVLGFILVKSLPRALFVGFS
                     FYLGSPVMERILNAIPTFVQDGINIAAGIMPALGFAILLQMLLKKDVFVYFVIGFALF
                     SYLHVPILGIAIFGACLAYIIVNMETKAAMGSRGEEMVEDDF"
     gene            10190..11014
                     /locus_tag="JXV47_001681"
     CDS             10190..11014
                     /locus_tag="JXV47_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017867003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAX1487731.1"
                     /translation="MTSSGKALTKDDLTKICIRSCALEASWNFERQQHMGFAFAMMPA
                     LEKIYSGNEEEKQKAAQRHLEFFNTAPPLSTFIMGIVASMEEENAKNPDDFDTSTITS
                     IKTALMGPLAGIGDSMFWGTLLVIGIGVGASLAKEGNILGPFLFLLIFNVPNFLLRYF
                     GVMQGYNFGTKLLENIESSGVMKTLTHAASILGLMVIGGMSGSMVSIKVAGSIGQGDE
                     ATKIQSIIDGILPNLLSVLCVFLIYWMLKKGFKTTYVLFGIFIFGIIAAFFGFLTT"
     gene            11049..12047
                     /locus_tag="JXV47_001682"
     CDS             11049..12047
                     /locus_tag="JXV47_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011968302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAX1487732.1"
                     /translation="MLNYNAKEMKKKGKRIYGIREDVEKIAKQAYDSGISNIFFTASG
                     GSVAVMQPFEYVLMTESSIPVYSMTAAELVLMGHKQLNEKSLVILYSKSGDTKETIKA
                     AEYLKERNVPTVGIVSKEDTPLEALSTYAINYLDGRPQEMPLYFLIMSIMNLNGEFPE
                     YTRFADELKNLPTALNSVREQADEKGKKYAEEFKEDPYQIWIGSGNLWGITYSYSMCV
                     LEESQWLRTKSVSSPEFFHGTLELVEKGVCVTLLKTEGETRLLDARVEKFAVQYTDKF
                     NVFDTKDYELPGISDEFRKYFCAPVMWAALGRVSVHLEDIRNHSLDKRRYYRVVEY"
     gene            12064..12918
                     /locus_tag="JXV47_001683"
     CDS             12064..12918
                     /locus_tag="JXV47_001683"
                     /inference="COORDINATES: protein motif:HMM:NF012515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487733.1"
                     /translation="MTAYVIGFGDNVVDYYENLNQKFPGGNAVNFAVNAKKSGVKAYY
                     VGSLSSDPDGVLLQHAISSEGVDISFSEVIDEPTEQAHVTIKDGDREFIGGVRGSRLT
                     PALSAELIDLMKNSSLVHTSCHSRTETKIKELKKYDVKVSFDFSDLDKYRTHEYLSDV
                     CPSIYIAQFSVATDDQEEINRLISECKDFEVPYLLFTRGSKSPVFVDTRENKTYEGFI
                     RKVESPHDTMGAGDAYFAAFASNFVLSKREKSMIEHVIDCFHKGANLAYETLMIDGSF
                     GHATPINP"
     gene            complement(13492..14742)
                     /locus_tag="JXV47_001684"
                     /pseudo
     CDS             complement(13492..14742)
                     /locus_tag="JXV47_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397514.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            15259..15342
                     /locus_tag="JXV47_001685"
                     /pseudo
     CDS             15259..15342
                     /locus_tag="JXV47_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009310545.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            15431..16842
                     /locus_tag="JXV47_001686"
     CDS             join(15431..15986,15986..16842)
                     /locus_tag="JXV47_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAX1487734.1"
                     /translation="MAKYPFELKLKIVKEYLSGVGEYRHLANKYGISSKSQVSDWVNA
                     YREYGEEGLLKKHQNQKYSVQFKLNALELYQTSEMSYREVASTLEMNNPALIANWMRN
                     FREAGIEGLSKEKGRPLTLTRKKENKKENTTTEERERIKALEKQVRSLQIENAFLKEL
                     RKLRKQEAQQRRKNQSHESSPASEDPFKLVELLETLKFPKATYMYWQKRFDRPNPDQE
                     IEEKMLEIRKEHKDYGCLRLKKELENQGIHVNKKKIQRLIKKLGIEVKSYTRKSRRYN
                     SYHGKVGTVAKNRIHRRFYTNICHQKITTDTTEFKYYEVDTTGVVRQKKLYLDPFMDF
                     YNSEILSYRISEKPNALAIMEGLEEAIQMTNDCPFRRTFHSDQGWAYQMNAYKNKLKQ
                     HKIFQSMSRKGNCLDNSPMENFFGLLKQEIFHGEVYRSLDELKTKIDQYIYYYNHKRI
                     KKKLNWRSPVQFREAVKTAV"
     gene            16917..18200
                     /locus_tag="JXV47_001687"
                     /pseudo
     CDS             16917..18200
                     /locus_tag="JXV47_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(18416..19228)
                     /locus_tag="JXV47_001688"
     CDS             complement(18416..19228)
                     /locus_tag="JXV47_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017867010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAX1487735.1"
                     /translation="MGDSKLTKKEINKVFWRSFALQGSESYTDMQGMGYSFSILPALN
                     KIYQGNDEKYYEAVYRNTEFFNTTPHISTFIMGMSLALEEENAKTDQFETETISSIKA
                     ALMGPVAGIGDSFYWGTFRVIAAGIGLSLAAQGNILGPILYFSIYTLLHFLGRYGCLR
                     IGYRMGANAIEKAFENNYLESFSLAASIVGLMSIGAMTSSLVRFTIPAVFKSKGGEIN
                     VQQMLDDIFPGILSLGLTFFVYFLLKKKVKVLWIILAIFVFSIVGVYIGLLG"
     gene            complement(19245..19976)
                     /locus_tag="JXV47_001689"
     CDS             complement(19245..19976)
                     /locus_tag="JXV47_001689"
                     /inference="COORDINATES: protein motif:HMM:NF015566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1487736.1"
                     /translation="MIECILIGIVGYLTTIDERYFGASMMNRPIIVGPVVGLILGDLH
                     QGILIGAALEAMFIGIVTIGAALPPDVGVAGTIATALAIKSGAGADVAVTLAMPFAVL
                     AQGLNMLAFTINSFTVSQGRKAIENRKLSSFQKWHFFPLIVRLPSAVLTFLVVYFGAN
                     ATESFVNIMPEKLMTGFTVASGLLPAVGFAMLIQGMIDKKSVPYFFIGYLLAAYLGVP
                     VVGVAVAAIMVALLVIQTKRNPVNI"
     gene            complement(19993..20448)
                     /locus_tag="JXV47_001690"
     CDS             complement(19993..20448)
                     /locus_tag="JXV47_001690"
                     /inference="COORDINATES: protein motif:HMM:NF015769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAX1487737.1"
                     /translation="MIKLLRIDDRLIHGQVAMAWTKSVSADYIIVVDDASANDKMKQM
                     ILSLAKPVSTGLDIITSADFLSTFEKRKNQNLMIVTSSPKSAFEIVNAIPGEVDSINI
                     GGLRYAEGKEKVNEYVAITSEDKNYLAKLKESGFKLIMQATPTGKAKIY"
     gene            complement(20441..20851)
                     /locus_tag="JXV47_001691"
     CDS             complement(20441..20851)
                     /locus_tag="JXV47_001691"
                     /inference="COORDINATES: protein motif:HMM:NF015567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAX1487738.1"
                     /translation="MYTIILASHKNLAKGMKETVEYILGPAPFIKVMTAYTDDNYDIE
                     KDTNILLDGTDKVLVITDLLGGSVNNHWMNYVYEKKLTKKITVIAGMTLSLIMELSMN
                     IEDYKLREKISMIIAESQKSIINCSELMEVEDND"
     gene            complement(21382..22341)
                     /locus_tag="JXV47_001692"
                     /pseudo
     CDS             complement(21382..22341)
                     /locus_tag="JXV47_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            22775..22961
                     /locus_tag="JXV47_001693"
                     /pseudo
     CDS             22775..22961
                     /locus_tag="JXV47_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252699.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            complement(23202..23417)
                     /locus_tag="JXV47_001694"
     CDS             complement(23202..23417)
                     /locus_tag="JXV47_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HAX1487739.1"
                     /translation="MKKFIIPCIFLFLSILLFSTSILVGSYLDSSGMLIEPAFFCVPL
                     GYLTLGLAFFTALYSFVKQRLLKKYSA"
BASE COUNT         7840 a         3878 c         4519 g         7658 t
ORIGIN      
        1 gaaagcaatt atcaacagta aggattacga aggatataaa gccaaacatc cagaagcgaa
       61 accatttaaa tacccacaag aaatgaagcg agcatggcgt aaaatgttag atgatgagtt
      121 gattccactt gaaaatgaat tgaggtaaat gagaagagtt aagaaaattg tacgattcaa
      181 agatagtagt aaagtggaag tgtagaaaat agggatagat gtcttttatt tgttcacatt
      241 ttataacgaa gtatttaaga cagctattga ataatgtttc ctccaccttt ttcattcatt
      301 taccccaccc cgttgttata tgaccgtgtt tcgagagaaa ccaataaaaa gcataggcta
      361 actaggggtt cctttttctt ttgatttttt ggaatccgct taagtgaaat gtatctgaaa
      421 tgaaacagag ataaagtgat tttttgctgt aatgacaagg ttttagctgt ttcagatacc
      481 atgtaaccca aaatagttta ttgagaaaat aggagagtat ttgatactaa ctagtaggaa
      541 aaaatgagat aaaaagtaaa tggaatcatt tcaggtaatc tcaaataaaa aatatacagg
      601 cctgtggcac tttacctacg ggactgtata ttttttactc tcagcgggct tgttttgact
      661 ccgtgtttga ctccgtcgta ttgattttaa atgatattcg atgaccaatt aataggtcgt
      721 ttttgaaatt tttgtctcta tatgactcag tttgataatt attgatagat cgatttgggt
      781 ctatatcgaa caagggaaga ttgcaaaagt cgaagcttaa aggattgata ttaaaggatt
      841 aagaggtaaa aaggtatccc cataatatcc tctgactccg tttttgacct cgcttatcat
      901 ccgttcatgt aagaatcaaa taattcgact gtttcatttt gccgattttt tgatacttta
      961 atataaatgt ccatgattgt tttagaagaa gaatgtccta gcctatcttg tacatctttt
     1021 acttgagcac ctgcttcaaa gagaagggta gcatgagtct ttctgaagcc atggactttg
     1081 attatcttca tatctgggaa cttccgtgct actttatcca tgacatggtt agggtagcct
     1141 ttgtaaagga agtccctttt tttattccct ttgatagtgc tgattacagg tatatcatct
     1201 atattatcta tccgaatccc tctagaaagg ttcttttatg ttacagaacg tttccatttt
     1261 ttagaatacg taaggttcca ttatcaattg aaattactcc ctttgatttg tctgtttttg
     1321 taggattaat acatagagag ccctcggata gttctactaa cgttttgttg aagcagatag
     1381 tttgattatc gaaatctatg tctctacatg tcagtccgag tatttctcct tttcgttccc
     1441 ctgtataaga agctattcta aagaatacta aagcacgctc atcttttaac ttatgcaaac
     1501 attcaaaaaa cagatatttc acatatatct aaaattcgga gattgaaaga atgaatttat
     1561 ctaagaattt tcactaatgt tgcgaatata atatcagaaa atttcgaaat aaattttgtt
     1621 aaaaattaga aaaatccgaa tacttagtag tggataaatt tttttcagga atagtacgtt
     1681 ttattaaaat gaaaactaat ccgacatcaa cttttttatc gaagcaaaca tcaagcggta
     1741 aaaagacctc tttagtttga aaagtgttgc tttcatattg atttaaattt tggttaagta
     1801 ggtaaattaa gaaatgatca gtgtaagtat ttcctgattt agcgcacctt gttcactttg
     1861 aaaatacagg tttttgatgg acagattttg cttcaaatgt ttaaagaaca tgccactgta
     1921 cttggtacag gtcggcgccc ccatttggag ttgcgtcaga tcgagtcgtg acgattcatt
     1981 ttgtacaaat tagaatttaa aattgaatac atgacgcgca cattttccca gagagccata
     2041 ttctgtaatt aatcacagca attagtgatt atgcacaatc taaaaaactg atttataata
     2101 aaaatattat tcaaataaat aataataact gcccgcatga tgttgacagt tacaatagca
     2161 catagataga ctggcaaaga tggttcttaa tctttcactt tggtcagaat tcttgggtta
     2221 tccttccagt gaaagtcagc agaaaatcct taatgcttac aaataatttt tgcgaaatag
     2281 gttttattgg taaaggactc aatcatgaat atgaattact tttatctggt aaatttggaa
     2341 aaattttgca aagaaataaa aattagacaa atttgctaca cataatcaaa gattaaaaaa
     2401 gtttttaaaa tatagttgtt tgaatgggga tatgaattag agaaaattgg ttgattcaac
     2461 gggtgctatc atttttgata gcgtcatatg tgaagtaagc acacctaatg aaaaaggttc
     2521 aggcttgctt tgaagactta ttaacaacta tgtcgactat ccttgactta gggtagagga
     2581 gtacctccac acaccttaat tagatgataa tgtttggact gtaggctact tagcggatta
     2641 agataaagag gaagtagaaa aagagccttg cggaaagaca ctttatctgt tatccgcgag
     2701 gctctttata catttaagca tatttaaaaa ttatttggaa acagtacttt caaactttgt
     2761 cttataagca gggtacttag atatttcata ttcaaacggt ttctgatttt tagcaaatcc
     2821 aatacttgta aagacaaaga ctggctcatt tttttctaaa tcaagataaa ggttttctaa
     2881 atctgttggc ggtgtaactt caattgagcg tttggcataa gctaatctaa ttcccctact
     2941 ttctaatact gagaacaggg attctttggc aaaatcatgt tcaacaattt caggtaaaac
     3001 agatagggga atgcaacttt ttgcaataca agttggatag tcatcgatgt atcgaattct
     3061 ttccaagaca agcactaaag tattctgctc aatctccaaa cattcactaa ttgttgaatc
     3121 agcaggtatg atggtttgtt ggataatctt agaactgatt ttctttcctt gctgaaccgc
     3181 atcttggaag aatccgataa aagagtcgag ttcgtggtca acatattttt ctgaagctgg
     3241 tttcactaga tacccgcgac cttcattttt agaaataatt ccttcgtctt ctaaagaagc
     3301 taaagctttc cgaattgttg gacgactcac cgaaaattcc tgggccaaat ctctttccga
     3361 aggcaataat tcagatttcc gatcagtggt gatatacact tttcgaattt gttcttttac
     3421 tttgtcaaaa atcatagtaa tccatccttt taccaaggta ttaacattat attaccattt
     3481 ttttgactta atatcccaga ttttccttca attaattcct tcgccgctaa ttgaccccac
     3541 aaatagccaa tatatcggtc ataaaaagtt ggagatgatc cacgctgaag atacgcaaga
     3601 tttaagtatt tggtttcttt tggtaaattt ttggtaataa attcaatgat tttttgtttg
     3661 ttagatatac cttctggtaa aagcaatata ggcgagtaga actccgactc aaatttttta
     3721 catattaagt gtaagtattc cttgtcgtct ctctcaaccc aataagtatt atttgcaatg
     3781 gaagcgtact ctggaagagc aaagcagcct cggcccatga cttccattat aataatacga
     3841 tcatgagcat tagcagtaga agttaaatca tcgattgatc ggattatagt gtttaaggcg
     3901 ctatcgaagc caagtgtata atcggtattg gggaaatcgt tatcaatagt ccctgggatg
     3961 acagatactt gtaattctga ttcatttttc aatagttcag ctcctttcaa ggaaccgtta
     4021 cctccaataa caattaagtt gtcgatctcc atcttattta ggttttcaat aataattttc
     4081 cgactttcga gatctctcat tttctcaaat ctggctgttc caataagtgt tccagctttg
     4141 aatacctcaa cttcttttag agaaactgag gcaatacatt ccttaaatat tccggcataa
     4201 ccattcttaa aaaagactac ttccgaatct ggttcgctat caattgtttt ttttattgct
     4261 aataaagctg aattcattcc gggagagtcg ccaccactac agataactgc gattttcatt
     4321 ttagatcctc ctaaaaaagg tgactgcgat tctattctcc cattagagaa aatgaagcaa
     4381 tcaaatgggc aatggagtcg cggtcacctt tttcatattt ttatgattag tattccattt
     4441 gcttataata acggcgagta gttaaagggt ggttacgttc ttcttctaga aaagcactaa
     4501 ttcgttcaaa gacagtagct aagacgactg gggaaataat ttttcgcgtg tcttccgaaa
     4561 tgccaggtaa gtcatagtcc tttgtatcaa ccgttacgtg aacatctgta aacttaggaa
     4621 cgaaattctt cacgcgttct gtgagaggtc gagaatcatc ttctccttct gtaatgatga
     4681 cacttacacc cgcttcaatt aattcaagag ttccatggaa gaagtctgct gcatgaacag
     4741 gacgagtctt aatccattgc atctcttcta aaatacacat gccatagtaa tatgcttccg
     4801 caaagctatc accagcaccg gttaaaatat gatatgaagt atctttgtgt ttttttgcaa
     4861 aagattttgc cattggttcc gcttgctctt tagcgtgcac taaggcttca ggtatttttt
     4921 ttaaatcctc aatataggta ttgtattgat tgatatcgat ttcatttctt tgtttcatta
     4981 agaagagagc aatcagcagt ccttgaaggt aataattttc tgaagatgta tcatctaaaa
     5041 cgtcgttata gatagaatat gttgcagctt tttctagggg cgttttagga cttcctacca
     5101 aagctaatgt tttgacgttc atttcattac agtattcgac taactcaagt gtttcttttg
     5161 ttgtaccaga taaagatggg ataacaacca aagatttgtt agaaaatgtt ttattgggat
     5221 gaatcataaa ttcggcagcg ataacacgat gaaaagggaa agtgctacga gttctcgcga
     5281 attcgattgt tgaatcaaaa agaataccaa ctcctccaga cccaataaag taaatttctt
     5341 ctaagtcaga tgcgatggat tctaaaatat tggaaatttg ttcatttgtt gcaacggcac
     5401 cagcttgagt ctttaaaaat ctttcttgat caaaattaaa cataaaaatc tctcctttga
     5461 ttaccaatgg taatattttg tttgcataaa taaaatacca caggtaataa aaagtgtcaa
     5521 atatttttta ggaaaaatac cataggtatt gttaaagtgg aaagatgttt ataaagaata
     5581 ttgaatttta tagtgaaaat catttattat taagtaaagg aggtgggttc atttgaaaac
     5641 gaaaatttta aaagaattaa atgatctact taacagctat gattttccac aatattttcc
     5701 agaagaatgt aacgcgcaat atattgccca aaaatttcaa ataaaaagaa atacggctag
     5761 taagcatcta aacgaactaa tggaacagaa aaaagttgtg aaaatcaatg gtcgtcctgt
     5821 tctttttttt ccagtccata caattgaacg gtatatatca cattcattag atagttttga
     5881 gttttcttca attgattcgt ttagagaaaa aatttcaaag aaaaaagcag atcatttttt
     5941 tgatgattta attggtgcaa aacaaagttt aaaagaagcg gttcaacaag ggatatcagc
     6001 aatgaaatat ccaggtggat taccaataat gtattttgga tcgtccggag ttgggaagag
     6061 ttacttagtg gaaaaactag ctgagtattg ccgacaaact ggtattattc atgagaatgc
     6121 tccgttcatc gagttaaact gcgctcagta ttttaataat ccagagttat taacaagtca
     6181 gttgtttggc catatgaagg gatcgtttac cggcgccgat tctgaccata ttggtataat
     6241 agaagcagca gacggtggaa tcgtctttct tgacgaaatt catcgtttac caccagaagg
     6301 acaagagaaa ctttttattc atatggataa aggcgttttt cgaagagttg gagatagtgg
     6361 tccttggcgt ttatcacatg ttagatatat ttttgcgaca acggaacagg aagaaaattt
     6421 ttttctagaa acttttcgac gaagaattcc gattgtttgt actttgccta attaccaaga
     6481 tagagaaatt agcgaacgaa aagagattgt cttccattta ttagagaaag agtctactct
     6541 gatcaataaa gaaatattag tttctgaagc cgcccttagt ttcctgattc gcttagattt
     6601 gtatggaaac attggtgagc tggatggact aataaaacaa actattgcga ataaactatt
     6661 tagtggaagc aataaaaaat atatcgaaat tcatatttct gatttaccta gcaggtactt
     6721 gctaacagaa aatattgagt taaaaaacca aattgcgagc caacggttct atatctttag
     6781 taatggtaac tatgttcatg attgtgacga gacttcaact gtaactacaa atttacgagg
     6841 tttgattcat cgtgtttcta aatattattc agagtgtcat gatgtgaata gaaatagtga
     6901 agagtttcga cgttttgtga aggaccaaat ggcagaattt aatgatcgtt ttatttacca
     6961 aaaaaattca gaagtcttag ttaagtatta tttaccggaa atccaaaata ttgttcaaaa
     7021 aatctctccc agtctttttg ttcacctttc tggcaatacg gtccaagcta tagctaccta
     7081 tctcgctatt agggatcaat gggggtatgg gaaagagaat gcttcagcga atgaaattga
     7141 aaagttatat gaaaacctaa agtgtaacta tttgacggat ttaaatgtat tcttactgat
     7201 cttcgagaac gccctggata caacattgac tatttgggat aaactgtata tcagtttgtg
     7261 tgttattagt gagaccggaa atgaagcgaa agacattaac gcaattattt tagcccatgg
     7321 atatgcgaca gctagtagta ttgctaatgt tgccaatcgt ttggttaatc agtttgtcat
     7381 agattctatt gatatgcctc tagatatcag ctttagtgaa gtaattgaca gattacttca
     7441 ctatatagag tatcgaaagc ctaaagatgg actagtgatt ttcgttgata tgggaagttt
     7501 agctcaaatt aagactgaaa ttgaacaagt aatcgaagtt ccaacaatga ttattaataa
     7561 tgttacaacc gaaatggcta ttgaaaccgc acaactgatt caaagtacga gtgatatcca
     7621 aaaggttgta aaaaaattgc cgtattctca gtttgaaaag caagttctat atcccatcaa
     7681 aattagaaaa cgtacaatcg ttgtttcctg caatactggt ttgggtacct ccataaaaat
     7741 taaagaaatg atggaaaata atttgtcgaa agacttgggc attgaatttc tgccatacga
     7801 aaatgaaact cttagagata ctcagcaatt agagtttctc attaaaacaa aggatatcat
     7861 tgccattatc ggaacagatg atccgcgtgt gtcgaacatt ccctatattt ctcttgaaga
     7921 attatttgat ggtgaaattg gcaaactcta taaagttctt ttgagagtct atggaaaaga
     7981 gattgctgag gcaattaatc aaaatattgt taaaaatagc tcattaaacc gcttgattga
     8041 cagtcttact attttagatg ccgaaaaagt tgtcaatcaa attgaggaaa gtttaaaaga
     8101 ttatcaaatg agggtgggga aaacgttatc atcattgtcc aaaattaatc tttatgttca
     8161 tatcagctgt atgattgagc gactaattcg taatcaggga gtaagtagtt atccagcaat
     8221 agatcagttt cttaagcgat acgaaactga ggttgcttct attcaaaagg cacttagtaa
     8281 gattgagaaa ctttataata ttaagattcc tatggaagag attgcatatg tgtgcaacat
     8341 cattgtaagt tattgataaa ataaagtgac actattcaca gcgatggaaa tagtgtcact
     8401 ttattttttg tacgcccttt catttaagtg gtgacagtaa ttggcacagt atttgctaat
     8461 aacaaagcga aaggagttcg ggtatgagac aaatattatg tatgagccac ggtcctctag
     8521 caaaaggaat gattgaaact ttgagtatta tcgtaggaga tttggataat attgattttc
     8581 gatgtgccta tgtcgatgga aataatgacg tagaaatgat catcgatgat tatctaaagg
     8641 aatctatggg aaatgagacg attgttgtaa ccgacatttt tggtggaagc attaataatg
     8701 agtggctaag acggttgcca gatctttcta aagtctattt gatttctgga atgaatttaa
     8761 gtcttttagt ggatttatat ttaaaattcc aattagtttc atctgatcag attgaagaaa
     8821 ttattgatca tgcaattcaa gcatcttctg gttcgattaa gttttgtaat cagctagatt
     8881 atgagcaaac ggttgatgac ttttaaataa aggagggaag agaatgatta aattagtgag
     8941 gatcgatcat cgtttgatac acggtcaagt tgctttaact tggacgaacg caatcagtgc
     9001 ggattgcatt ttagtagcga acgatgaaat tttgaatgat ccaattcaaa agacaacttt
     9061 gaaattagcc gcaccacata acgtgaaggt tgttatcaaa tcaattcaag attcgattga
     9121 tgcaattaat agtgggaaga cagataaata caaactattt gtagttacca aaaccatttc
     9181 cgatgctaaa cggttggcaa atggggttga acaaattaaa tctgtaaata tcggtagtgt
     9241 taaggaaact agtggcagta gcgctttgac gcatacaatt tttgtaacag aagaggaacg
     9301 agcagaactt aaaggaatgg tctcagaggg cattgaagtg ttcgctcaac aagttccaac
     9361 agataaggca atagatttaa aaaaatcttt gtaataaaaa aataaggggg taatttcatg
     9421 gatagtctct tagtacaagc aattttgctt ggtctcttga ctgcgttcat cgtaattgac
     9481 tggatgacag gtacgaataa cttatcaaga ccaatcgtat cttccgtctt tgttggttta
     9541 attatgggcg atcttaagat ggggattatg atgggggcaa cactggagtt agcatttatc
     9601 ggagcaataa caatcggagc ggcacgtccg cctgatacgg tatctggtgg gattttaggg
     9661 actgcgtttg ctattgcaac tggcaaggga gcagaatttg cgttgacctt ggcattccca
     9721 atcgctgcgc tattcttatt agttgataat ctactaacat tgcttgttct accaatgatt
     9781 gctagaaagg cagatagata tgctgaaaag ggcgaactaa aaaatgtgtc gaaaatgcat
     9841 gttttaggtt ttatcttagt aaaaagttta ccacgggctt tatttgtcgg attctcattt
     9901 tacttaggaa gtcctgttat ggaacgaatc ttaaatgcta ttccaacttt tgtccaagat
     9961 gggattaaca ttgctgcagg cattatgcca gcactaggtt ttgctatttt attgcaaatg
    10021 cttcttaaga aagatgtctt tgtatatttc gtaattggtt ttgcactctt tagctactta
    10081 catgtgccga ttctggggat tgcaatcttc ggcgcatgtc tagcttatat tatagtaaac
    10141 atggaaacca aagctgcaat gggttcaaga ggggaggaga tggttgaaga tgacttctag
    10201 tgggaaagct ttaactaaag atgatttaac aaaaatttgt attcggtcat gtgcattaga
    10261 agcatcatgg aattttgagc gccaacaaca tatgggcttt gcttttgcta tgatgccagc
    10321 gttagaaaaa atttatagtg gcaatgaaga agaaaagcaa aaagcagctc aaagacatct
    10381 agagtttttt aacacagctc cgccattatc aacattcata atgggaattg tggcttctat
    10441 ggaagaagaa aatgccaaaa atcctgatga ctttgatact tctacaatca cttctattaa
    10501 aactgcattg atgggaccat tagctggtat tggtgattca atgttttggg gtaccttatt
    10561 agttatcggt atcggtgtag gtgcttcatt agcaaaagaa ggcaatattt tgggtccatt
    10621 tttattttta ctaatcttca atgtccctaa ttttcttctc cgttactttg gagttatgca
    10681 gggatataac tttggtacaa agctattaga gaacattgaa tcctctggcg tcatgaaaac
    10741 gttgactcat gctgcctcaa ttttgggtct tatggtaatt gggggcatgt ctggaagtat
    10801 ggtatcaatc aaagtagctg gttctattgg acaaggtgat gaagcaacaa aaattcaaag
    10861 tatcattgat ggtattttac caaatctgct gtcagtatta tgtgtatttc tgatttactg
    10921 gatgcttaaa aaaggcttta aaacaactta cgtgttattc ggaatcttta tctttggtat
    10981 catagcagcc ttcttcggat ttttgacaac ttaattgaat aatctaaata attgtaagga
    11041 gagaactaat gttaaactat aatgcaaaag aaatgaaaaa aaaaggcaaa cggatttacg
    11101 gtattcgtga agatgtagaa aaaattgcaa agcaagctta tgattctgga attagtaata
    11161 ttttctttac tgcttctggt ggatcggtag ccgtaatgca accatttgag tatgtattga
    11221 tgactgaatc aagtattcct gtttactcta tgactgcagc tgagcttgtc ttaatgggac
    11281 ataaacagtt gaatgaaaaa tctttagtaa tcttatactc aaaatctgga gatacgaaag
    11341 aaactattaa agcagctgaa tatttaaaag aacgaaacgt gccaaccgtt ggtattgtaa
    11401 gtaaagaaga tacaccgtta gaggctctat caacttatgc aatcaattac ctagacggcc
    11461 gccctcaaga aatgccactt tatttcttaa ttatgtctat catgaatttg aatggggaat
    11521 ttcctgaata cactcgtttt gctgatgaac tgaaaaactt accaacggct ctgaattcag
    11581 ttagagaaca ggctgatgaa aaagggaaga agtatgccga agaatttaaa gaagatcctt
    11641 atcaaatttg gattggtagc gggaatttat ggggaatcac ctactcttat tcaatgtgtg
    11701 tgcttgagga atctcaatgg ttgcgtacaa agtctgtctc atcaccagag tttttccatg
    11761 gtaccctcga gttagtcgaa aaaggagttt gtgtaacact tttgaaaact gagggggaaa
    11821 cacggctttt agatgctcga gttgaaaaat ttgcggtcca atatacagat aaatttaatg
    11881 tttttgatac taaggattat gagctaccag gtattagtga cgaatttcga aagtactttt
    11941 gtgctccagt tatgtgggca gccctaggtc gcgtcagtgt tcatcttgaa gatattcgga
    12001 accactcttt ggataaacgt cgttattacc gagtagttga atactaaaag taggtgatta
    12061 attatgacag cgtatgtgat tggatttggc gataatgttg ttgattacta tgagaatttg
    12121 aatcaaaaat ttccaggggg aaatgcagtt aattttgctg tgaatgcaaa aaagagtggt
    12181 gttaaagcat actatgtcgg tagtctatca tctgatcctg atggcgtgtt attacaacac
    12241 gccatcagtt ctgaaggtgt tgatatctct ttctcggaag ttattgacga gcctactgag
    12301 caagcacatg taactattaa agatggagat agggagttta taggtggcgt gcgtggctcc
    12361 cgattgacac ctgctctctc agcagaactt attgatttga tgaagaacag ttcattagtt
    12421 catactagtt gccatagtcg aacagaaaca aaaattaaag aattaaaaaa atatgatgtt
    12481 aaagtttctt ttgatttttc tgacttagat aaatatagaa cgcatgaata cttgtcagat
    12541 gtttgtccgt caatttatat tgcacagttt tcagtcgcta cagatgatca agaggaaatt
    12601 aatcgcttaa ttagtgaatg caaggacttt gaggttccgt atcttctttt tacgcgtggt
    12661 agtaagagcc ctgtttttgt tgacactcga gagaataaga cttatgaagg attcattcgc
    12721 aaagttgagt cacctcatga tacaatgggc gcaggtgatg catactttgc agcttttgca
    12781 agtaattttg tcttatctaa acgtgaaaaa tcaatgatag aacatgttat tgattgtttt
    12841 cacaaaggtg caaaccttgc atatgaaaca ttgatgattg atggctcctt tggtcatgct
    12901 acacctatta acccttagct ttgtgctttg ggcttttatt gctggaattt gtatagtaga
    12961 ctcatcataa ctatattttt gtatgtgaaa aggcaagagg ctatgatgaa aataacactg
    13021 gctaattgca tgagggagca tatcgttgtt aaagcgtcat tgatagtatg aataaatatc
    13081 tcgataatat tatattgtta tttacttaat ttattgatta gtcaagcaaa gataatcttc
    13141 tgttacttaa cgagactagt aggtacaagc acttcatgtt atgtacgacc caaaaatatt
    13201 gctgttgatt atttgctgaa attattgcga gcttcaattt atttttaaag gacttggtag
    13261 gctgcgtgat gaaataagac ttggaaggct gtctaaacca atatatagta gactaaatag
    13321 taaaaaagag catggtaatt gtctctttgt caataagtct aatggtaata agacaagttg
    13381 gagattgaga atatttttat tgtgtaacct attttgaagc gtacttaact agccccggcc
    13441 aaaatcaaat tttttcgggg tatatcaagg gtttgcgtca ataacagaat gttatttatc
    13501 tatcacgttc cttggtggcg tgtagagttg atggttacgt agtagcgtat ctaccagacg
    13561 cgtaaatttt cttgcggtta agacgtgtgc tcgtttgtgt ttatttttgg gacctcttta
    13621 catttgcttt gataaaaagc tttatattga ggaagatatt tttttacaga gttggaagct
    13681 tcaactaagt agtatctaaa atagcgactc ctttgttttg tcagaggtgt attttgtgac
    13741 cgatagttaa cagattgttt gcctttccaa cataagcctg cgtattttgc caattttgtt
    13801 tgatcttcaa atcgttcaat ttgaccgatt tcagcgatta atccagcggc gtgtaccttt
    13861 ccaatacctg gaacactagt caaatattga tattctggaa taacgacaac aaattgctcg
    13921 gttgctttat ccaagtcttt gatgttcttt tcaagcgcac gaatttcaca tacaaaaaca
    13981 tttagaacga cattgatgga ttcttatgca agactatcta accgataact cacggcaatt
    14041 gcacgttgaa tcgatttggc atttttttct ggatctttaa agcgacattt cctttttctt
    14101 ttagtaagtc acagaaagct tccaaaggaa gcacagccaa ttcatctagc gtgaagtctt
    14161 ctgtcacaag agtaatgaca gtggcactat agagacttgt cgattcatcg cgcatttatc
    14221 gagtaagcgt attgcatttg tacgttagat tttccagaaa gtgttgtttt gtacgagtga
    14281 agttgcttaa tgagtcgata gcgagtgcgt gttaaacgct gtaaagccac gtacttctct
    14341 tctttgatag gagaagttgt gaaccgttga atacgcaata aatcagcaat tcttaacgcg
    14401 ttgtttcgat cagtcgtatc ttcctcaaac atgcgactga attgtttcat ccgaaaagga
    14461 ttttcaatcc tcacaagtgc attgagtttt tttagctctg catcttcatg gaaaaacatc
    14521 gaaggatgaa agctgtacat ggacgtttaa ttccatctca ataacgattt gaccgaagtg
    14581 attgttttca ttgaacacaa gaatcagttc tcgtgtcaat ggagcccttt caatgtcatt
    14641 agcaacagaa ttttcagtca atatagatag ctgatcgtcg tctgttagga agcaaacgtc
    14701 taatttttca gaactaacgt cattaccaac aaataatttc atggaataaa aacctatttt
    14761 cgatataaat tctagaaaat gcttcgatac tgtgggattc cacagaaact cactgtgtgg
    14821 tcacgacctc gcctaataga atacggtaat aaaagagcta atgagttgat agtaaacaca
    14881 gcgctttgga taacagactt atgaaggtag acaaagctac aggactgatt agcaaattct
    14941 cgttgaatcc tttccataca tccattgtac tctgagaaat cacacaataa cgaaataaat
    15001 tccggaagga atatgttatt caaaaaaatt tgtgttttat agatacttta aaagaaactt
    15061 attaggcaaa atatatttta cgaagactga tgagttgtgc aaaatcaaat ctgagtcaga
    15121 atgaacttca ttctagctca gatttttgtt taatgacttc agtcagtttc ttgcattacg
    15181 tgaatgaaaa tgggactggt gatgtccaaa ccctaaaaag ttagaccaaa atctaacttc
    15241 aggggggatg gtatttttat gggaaaatat agctttgaat tcaagtcaac aatcgttcaa
    15301 gagtatcttg aaggagaagg tggattagga tatttagcaa aaatacaagg agtgagatca
    15361 aaaaaaggta cacggatgga tcaatcaaaa gttagaccaa aaaatctaac ttttgggggt
    15421 cgttatttgt atggcaaaat atccttttga attaaaacta aaaatcgtta aagaatatct
    15481 tagtggcgtg ggcgaatatc ggcatcttgc caacaaatac ggtatttcaa gcaagtctca
    15541 agtaagtgat tgggtgaatg cctatcgtga atacggagag gaaggtctat tgaaaaagca
    15601 tcaaaatcag aaatattctg ttcaatttaa gttaaatgcg ctagagttat atcaaacaag
    15661 tgagatgtcc tatcgagaag ttgccagcac tttagaaatg aacaaccctg cgcttattgc
    15721 caattggatg cgtaatttca gagaagcagg tattgagggg ctctcaaaag agaaagggcg
    15781 accacttact ttgactagaa aaaaagaaaa caaaaaagaa aatacaacaa ctgaagaacg
    15841 cgagcgtatc aaggcattag aaaagcaagt ccgatccctt caaattgaga atgccttttt
    15901 aaaagagttg aggaagctgc gaaaacagga agcccagcaa agacgcaaga atcaatcgca
    15961 cgaatcatcg ccagcctccg aggatcattc aaactagttg agcttcttga aacattgaaa
    16021 tttcctaaag caacctatat gtattggcag aaacggtttg acagaccaaa cccagaccaa
    16081 gaaattgaag aaaaaatgct tgaaattcgc aaggagcata aagactatgg ctgtctgcga
    16141 ctaaaaaaag aattagagaa tcaagggatt catgtcaata aaaagaagat tcaacgtctg
    16201 ataaaaaaac taggtatcga agtaaagtct tacactcgaa aatctcgacg gtacaattct
    16261 tatcatggga aggttggcac tgtcgccaaa aatcgtattc atcgtcggtt ttatacaaat
    16321 atctgtcacc aaaaaattac aactgatacc acagagttta agtattatga agtagacacc
    16381 acaggtgtcg ttcgtcagaa aaagctgtat ttagatcctt tcatggattt ctacaatagt
    16441 gaaattctat cttatcggat ttctgaaaaa ccaaacgcac tagccataat ggaaggatta
    16501 gaagaagcaa tccagatgac aaatgattgt ccatttcgta gaaccttcca ttcagatcaa
    16561 ggatgggcct atcaaatgaa tgcttataag aataaattga agcagcataa aatcttccag
    16621 agtatgtctc gtaaagggaa ttgtttagat aactcaccta tggaaaactt ctttggttta
    16681 ttaaagcaag agatttttca tggagaagtc tatcggagtt tagatgaatt gaaaacaaaa
    16741 attgaccaat atatctatta ttacaaccat aaacgcatca aaaagaaatt aaattggcga
    16801 agtccggttc agtttcgaga agctgtaaaa acagctgtct aacagttaat tttatcgtac
    16861 aaaaaaggag tggatttctc cactccataa aagtctaact ttttggggtc gctacaaatg
    16921 cttatcgaga atttggagaa gaaggcctct tgcgtaagcg aaataagcga agttattctg
    16981 ttcaattcaa gatagatgcg atagagttat aaaaaacggg tgagctatcc tatcgtgaag
    17041 tggcgaatca tttagggata aaccaacctg cgttagttgt caattggatg aaaatttttg
    17101 ttcaaaagga ttgcacgggc tctcaaaaat gaaagggtcc tcctccattt tgtctaagaa
    17161 agaataaaag gaagaaacaa gcaaactgac gcctaaagag cataatcgta tcaaagaatt
    17221 ggaaaaataa gtgcgtttcc ttcagattga gaataccttt ttaaaagaat tgaggaagct
    17281 tagaaaacag gaagtctaac aaagacgaac gaatcaatcg cacgaatcat cgacaacctc
    17341 cgaggatcat tcaaattagt tgagcttctt gaaaccttga aatttcctga attaaccttt
    17401 atgtattggc aaagacgatt tgatcgaaga aattcagatc aagaaatcga agaggaaatg
    17461 cttaaaataa gaagtcaata taaagattat ggctatttac gtatgacaaa ggaattgtgg
    17521 gaccgtgggt tccatgttaa caagaaaaaa gtacaacgtt tgattcgaaa gctgagtatt
    17581 gaagtacgat catttacgag aaaatatcgc cgctataata cttatcgtgg aagaatcggc
    17641 atgattacaa aaaatcgaat tcatcgacgc ttttacacaa gcaactgtca tcaaaaggtt
    17701 acaacagata cgacagaact aaaatatttt gaaatggata aatacggtgc caatcgtgaa
    17761 aagaagctgt atcttgatcc atttttagat atgtacaaca gtgaaatttt attttatcgc
    17821 atttctgaaa agccaagtgc gttggctatc atggaagctt tagaggaagc tatctgcgca
    17881 acggaatgta tctatcgtcg aacttttcac tccaaaaagg atggacctac caaatgaaag
    17941 cttatagtca taagttgaaa gaacataaga tcttccaaag tatgtcccgt aaggagacct
    18001 gcttagataa ttcgatcatt gagaacttcc ttagtctatt aaagcaggaa atttattatg
    18061 gaagagacta tcgtatcttt gaagaattga agcaagccat tgatggctat attcattact
    18121 acaaccatga gcgtatgaaa aggaaactaa actggcagag tctggtgcaa tttagagtaa
    18181 tagcattcaa agctgtctaa aatcatcaag aaaagcaaag aaaaacggag tgaattttct
    18241 ccactccgaa aacatctatc ttttttaggt cactacagaa tcaattctga ttcatcagac
    18301 ccataaatta tagatcctaa taatttatac catgctcttt ttactcatat ttacatttat
    18361 ctttgggtat tttatggttt aagttgatgt ctgatctagt tttattctgg attaattaac
    18421 ctaataatcc aatataaact ccaacaatac taaagacgaa gatagcaagt ataatccaaa
    18481 gaacctttac ttttttcttt aatagaaagt aaacaaagaa tgttagcccc aatgagagaa
    18541 ttcctggaaa aatatcatcg agcatttgct gaacatttat ttctccacct tttgatttaa
    18601 atacggcggg aatagtaaag cgtaccagag atgaggtcat ggctccaatt gacattaaac
    18661 ctacgataga tgctgctaac gagaaacttt caaggtaatt gttctcaaat gctttttcaa
    18721 tggcgtttgc tcccatccga tatccaatac gtaagcagcc atatctgcca agaaaatgta
    18781 acagcgtata aattgaaaaa tacaatattg gacctaaaat gtttccttgg gcagctaaag
    18841 ataagccgat gccagcagca ataacgcgaa atgttcccca gtaaaaacta tcaccaatac
    18901 cagctacagg ccccatcaat gcagctttta tcgatgaaat tgtttcagtt tcaaattgat
    18961 ctgtttttgc attttcttct tcaagtgcta atgacatacc cataataaag gttgaaatat
    19021 gaggcgttgt attaaaaaat tccgtatttc ggtaaacagc ttcataatat ttttcatcat
    19081 tcccttgata tattttgttt aaagcaggta atatagaaaa actatatccc attccttgca
    19141 tatcagtgta tgactcggat ccctgtaaag caaatgaacg ccagaaaacc ttgtttattt
    19201 cttttttagt taatttagaa tctcccataa ttatcactct ccctttaaat atttacagga
    19261 ttgcgtttag tttggataac taataaagca accataattg cagcaacagc tacaccaact
    19321 acggggactc ctaaatatgc cgctaaaagg tatccaatga aaaaataagg aactgatttt
    19381 ttgtcaatca ttccttgaat tagcatggca aatccaacag cggggagtaa accagaagct
    19441 acggtgaaac cggtcattaa tttttctggc ataatattta caaaactttc tgtagcattg
    19501 gcaccaaaat atactactaa aaatgtaagt actgcggaag gtaagcgaac gattaatgga
    19561 aaaaaatgcc acttctgaaa agatgataat ttgcggtttt caattgcttt tctaccttgt
    19621 gaaacggtaa aggagttaat cgtaaaagcc aacatgttta atccttgtgc caatacagcg
    19681 aaaggcatcg ccaatgtaac agctacatca gcacctgctc cactttttat tgctagagcc
    19741 gttgcaatag taccagctac acctacatct ggtggtagtg cagcaccaat cgttacaatg
    19801 ccaataaaca ttgcttctaa tgctgctcct atcaagatgc cttgatggag atcccctaag
    19861 ataagtccaa caacaggtcc aactattatc ggtcgattca tcatagatgc cccaaaatat
    19921 ctttcatcta ttgtcgttaa atacccaact atgccaatta aaatgcattc aatcattctt
    19981 attccccacc ttctaataaa tcttcgcttt tccagttgga gtagcctgca taattaattt
    20041 gaagccggac tcctttaatt ttgctaagta gtttttgtct tctgatgtga tagccacata
    20101 ctcgttaact ttctcttttc cctcggcgta ccgtaaacca ccgatattaa ttgaatcgac
    20161 ttcccctggg atagcgttta caatttcaaa tgcgctttta ggggaactag tgactatcat
    20221 caaattttga tttttccttt tttcaaaggt acttaaaaaa tctgctgaag taataatatc
    20281 tagtcccgtt gatacaggtt ttgctaatga taaaatcatt tgtttcattt tgtcattagc
    20341 agaggcgtca tcaactacaa taatgtagtc agcagatacg gacttagtcc aagccattgc
    20401 aacttgaccg tggatcaggc gatcgtcaat tcttaatagt ttaatcatta tcttctacct
    20461 ccattaattc tgaacagttt ataatgctct tttggctttc agcaataatc atggaaattt
    20521 tttctctcaa tttataatct tcaatgttca tacttaattc cataattaag gacaaagtca
    20581 tacctgcaat tactgtaatt ttttttgtta attttttttc gtaaacataa ttcatccaat
    20641 gattatttac gctaccacca agtaaatcag tgatgacaag gactttatca gttccatcga
    20701 gaagaatatt cgtatctttt tcaatatcat agttatcgtc tgtgtatgca gtcattactt
    20761 ttatgaatgg tgcagggcca aggatatatt cgactgtctc tttcattcct ttcgctaaat
    20821 ttttgtggct tgcaagaata attgtgtaca taatccacct ccatttattt ataaataata
    20881 taccattggt aatctaaatg tcaataaatt atttcgtatt aagaataaat aaaatacctt
    20941 tggtaattag tggggcgaat ctaaaaactt taactaaaat tctcttttgt aaattttttt
    21001 gaacgcggct atcgtggtga ttttttattt ctgtttgttt aatgaatttg taaattagga
    21061 ggtgattttt gtgatggtgt aaacaaagcc tataaaaatg aagtaaagca ttgtgttttg
    21121 tccagatgtc aaatctttta tgtatcggtt gtatgtatag tatgttacac ccaaaataga
    21181 taacccaagt ccaaatggag agacagatgt tctttatatt actggcgaag acatgaagta
    21241 ttcttataaa atatctaaaa atgagtataa gtttaaagaa aataatttat ctatataaac
    21301 tattctgctt tgattagcaa gtctttcaat cggtaaaata ttatttgaat agatgggata
    21361 tggtttatta ttttctaaat gtcaaattaa gttagacaat tgctcctcac ttatgtaact
    21421 caaaaatact tctaacgatg ttcgataatt taaagatttc cttggtatat gatttctttt
    21481 ggaggcaacc gccgccacaa atttttggtc aacctgattg aaatccattg tattaggaag
    21541 tccgtcttta cgtaacaatc cattagaatg ttcatttaat ccccgttgtg acagcgttcc
    21601 aggatctgca aaataaatag aaatatcgtt agcattactc atgtttttcc aattcgaaaa
    21661 ttcttttccg caatcaaagg taatggattt gaacaagttt cggggaagct tttgtagcca
    21721 gtcagttgtc actttttcaa tatctagtgc tttccgtcct tcgggtttta aagtaataat
    21781 cacttttgac aagcgctcaa ccagcgtgat gacagcactt ttatgatgga cacccacaat
    21841 agtgtcgcct tccaaatgtc caaattcctg ttgaaattca ggatagtccg tgagacgttc
    21901 tgaaatattc cgtttgaagg cttgtttccc tcgacgttct ttatgcccgt tgggtttccg
    21961 ttttcctttc atgggtagtt tcgagcaatc aaattagttt gttttaaact tgcgataaag
    22021 ggttcgaaca gaacatgaaa ttgaaaactc agcacgaccg ataatcacat cgggtgtcca
    22081 tccttgcgcc accttgtttc ggatatacgc atcttgttct gctggcaaac aaatgggtcg
    22141 tcggccgcac cgtgttttat ttttttgata ttgttggtaa tagtcatgga tagattggcc
    22201 ttgtttcagg aagttgtaca cattgtagat ggtctgtctg gaacgatttg aggtcttagc
    22261 gactacggta acagattgat gcatattgaa ataggcttct atcatcacga gttcatttgt
    22321 tgtaagatgg gtataggtca tttgtcttca ctccttataa ttctttggtc ggaactattt
    22381 tgagtgtagc acaaatgact tttttagttg tctagcttaa ttttacaatc tgcgtttaat
    22441 aaactctcag tgggatagtt tgactccgta tatgactccg gttgatttga ttgaattcag
    22501 atgattatac atactataaa tttctctatt atgttgccat ttgatttgaa taatgctgaa
    22561 agaaggattt tagtctataa cgaacaaggg aataaaacca ataaaaaaag atatagaata
    22621 tcaatataac aaaaagagat tgtgacataa ttctctgaaa aaagctctag aaatgacgag
    22681 tcattcgtca tttctggagc tttttaggta aaataaaaga gtacgagagg atactcgcac
    22741 tctaaatcat tcaacccttg aaaggatcaa aatcatgcat acaaattata acatgaatca
    22801 actcacttta gatatcacaa cttcttattc caaaagaaga tagcaccgct gggtttgtca
    22861 atgaactcgt tgaaaccctt gaaatcaacg agccgtatct ttttggccgc cctaggaatt
    22921 gtgatttgag tgccatgtta aaattggttc ttttcgcata ttgaaaatga ttgaagagga
    22981 ctatcggtat tacaaaagac aatataacca gcaggtgaaa aaatggagaa ggtaattccg
    23041 aaaaaagctt cttttggcga ttgggaataa ttgttggtaa tggaggaata aaatgaatgt
    23101 ttatgcagac gtttgatgtc tacatcaaca tccattctta atactcgaag gttcgttgtt
    23161 gaaaaaacta acttttcttc aacagaggat ttacgtgcaa atcaagccga gtatttcttc
    23221 aataatcttt gtttgacgaa actgtataag gcagtaaaga aagcaagtcc taatgttaag
    23281 tagcccaacg gaacacaaaa gaacgctggt tcaatcagca ttccgcttga atcgaggtaa
    23341 gaaccgacta ggatggaagt tgaaaataac aaaatactca agaaaagaaa tatacaagga
    23401 ataatgaatt ttttcatggt gtctccttct ttgtttttct agattatata gaatagaacc
    23461 taggaaaaga taagtgtgac aaaattgata ggtgtgaaag gcattgagat atcaaccagc
    23521 tttatccttt ggagtatgct attgtgatta atgagacaga ggatgtggga ccagacgata
    23581 ctgaatcaac ggaaattgtt ctaaaccacc atcaaatagt agtttttcta gtatttgaag
    23641 gtgatttttt tatgttcgaa agtaactgta aaaaagataa ataatcggca gttattcttt
    23701 cacataagta ggttggatgc aggtgagaga agtttattgt atgagaggaa gattggtaat
    23761 ctaactatag ttttataact aatatcagtt taagctcgat tatttttgtt tcaaagtaaa
    23821 attggaacag aaatatagaa tagacatatt gtagccgata gtttattatg cttctagaca
    23881 cgttgaactg gaggg
//
LOCUS       DADGKS010000040        23831 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.040, whole genome shotgun sequence.
ACCESSION   DADGKS010000040 DADGKS010000000
VERSION     DADGKS010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23831)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23831)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23831
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.040"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(54..788)
                     /locus_tag="JXV47_001695"
     CDS             complement(54..788)
                     /locus_tag="JXV47_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAX1487740.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1115..1525
                     /locus_tag="JXV47_001696"
     CDS             1115..1525
                     /locus_tag="JXV47_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HAX1487741.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1518..2219
                     /locus_tag="JXV47_001697"
     CDS             1518..2219
                     /locus_tag="JXV47_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HAX1487742.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2219..3805
                     /locus_tag="JXV47_001698"
     CDS             2219..3805
                     /locus_tag="JXV47_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAX1487743.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3824..4045
                     /locus_tag="JXV47_001699"
     CDS             3824..4045
                     /locus_tag="JXV47_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HAX1487744.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4042..4803
                     /locus_tag="JXV47_001700"
     CDS             4042..4803
                     /locus_tag="JXV47_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HAX1487745.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5183..5692
                     /locus_tag="JXV47_001701"
     CDS             5183..5692
                     /locus_tag="JXV47_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAX1487746.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5767..6306)
                     /locus_tag="JXV47_001702"
     CDS             complement(5767..6306)
                     /locus_tag="JXV47_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HAX1487747.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6446..7057)
                     /gene="rpsD"
                     /locus_tag="JXV47_001703"
     CDS             complement(6446..7057)
                     /gene="rpsD"
                     /locus_tag="JXV47_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HAX1487748.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7373..8170
                     /locus_tag="JXV47_001704"
     CDS             7373..8170
                     /locus_tag="JXV47_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-nitrite transporter"
                     /protein_id="HAX1487749.1"
                     /translation="MNPVSPLFEKIDASIEKKANLFENSFSRYAVRAVLACLFLTLGT
                     AVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAELGTSNMLYMTVGVFRQRLA
                     LSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNFMLESIAVKLAKPSATILV
                     EGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLGYEHVIANFPAFTLTYFAS
                     HGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQSKSSYVD"
     gene            8198..8833
                     /locus_tag="JXV47_001705"
     CDS             8198..8833
                     /locus_tag="JXV47_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HAX1487750.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8853..9626
                     /locus_tag="JXV47_001706"
     CDS             8853..9626
                     /locus_tag="JXV47_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAX1487751.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10034..10831
                     /locus_tag="JXV47_001707"
     CDS             10034..10831
                     /locus_tag="JXV47_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HAX1487752.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10809..11222
                     /locus_tag="JXV47_001708"
     CDS             10809..11222
                     /locus_tag="JXV47_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487753.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11206..13851
                     /gene="mutS"
                     /locus_tag="JXV47_001709"
     CDS             11206..13851
                     /gene="mutS"
                     /locus_tag="JXV47_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAX1487754.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13869..15977
                     /gene="mutL"
                     /locus_tag="JXV47_001710"
     CDS             13869..15977
                     /gene="mutL"
                     /locus_tag="JXV47_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HAX1487755.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRQTGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15999..16559
                     /locus_tag="JXV47_001711"
     CDS             15999..16559
                     /locus_tag="JXV47_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HAX1487756.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16644..18632)
                     /gene="treP"
                     /locus_tag="JXV47_001712"
     CDS             complement(16644..18632)
                     /gene="treP"
                     /locus_tag="JXV47_001712"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HAX1487757.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18855..19568
                     /gene="treR"
                     /locus_tag="JXV47_001713"
     CDS             18855..19568
                     /gene="treR"
                     /locus_tag="JXV47_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HAX1487758.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19645..20091
                     /gene="msrB"
                     /locus_tag="JXV47_001714"
     CDS             19645..20091
                     /gene="msrB"
                     /locus_tag="JXV47_001714"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HAX1487759.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20262..20864
                     /gene="ruvA"
                     /locus_tag="JXV47_001715"
     CDS             20262..20864
                     /gene="ruvA"
                     /locus_tag="JXV47_001715"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HAX1487760.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20877..21878
                     /gene="ruvB"
                     /locus_tag="JXV47_001716"
     CDS             20877..21878
                     /gene="ruvB"
                     /locus_tag="JXV47_001716"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HAX1487761.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21907..22485
                     /locus_tag="JXV47_001717"
     CDS             21907..22485
                     /locus_tag="JXV47_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAX1487762.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22537..23019
                     /locus_tag="JXV47_001718"
     CDS             22537..23019
                     /locus_tag="JXV47_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HAX1487763.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23136..23510
                     /locus_tag="JXV47_001719"
     CDS             23136..23510
                     /locus_tag="JXV47_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487764.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7781 a         4286 c         5115 g         6649 t
ORIGIN      
        1 taaaaaaact tggtacgcaa tcgctgtacc aagttttttt atttagcttt tgattaagcc
       61 ataaataata atttatataa gaatactgct acgacaccag cacagatagg tgctacaact
      121 ggtacccatg catatcccca ttgagaagaa cctttatgtt tcaatggaag aagtgcgtgt
      181 acaagacgtg gagcaaagtc gcgggctggg tttagtccag gacctgtagg accaccaagt
      241 gaagcaacta atgtccatac aaggaaacca agtgctaagt gagctgtacc aagattatct
      301 tggaagaatg gtgcttttgt aatacctagg gcaccaaaga ataaaacgaa tgaaccaaag
      361 aattcattga cgaaaccatt gaatttagaa ccaacgctgt tgattgttga gaatgtacct
      421 aacacatggt ttacgtcttc tgtttggtcg tagtaaggtt tgtaacaagc tactacgatc
      481 aattgtccaa tcgctgcacc aatcaattgt gcaatgatat aaggaacaac ttcagcccaa
      541 gggaatagac cattagatgc taaagcaatt gtaaatgctg ggttgatgtg gttaccgctg
      601 attccaccaa aaatcattgc tggcatcata accccgaatc catacccgac agcaatcagc
      661 atccagtcac tgccatatcc ttttgtacct tttaaatcta cgtttgctac agcaccgtta
      721 cctagaacga ttagtaatgc tgtaccaatc atttccgccg caagacgggt cattagtgag
      781 taatccataa atacctccaa aagttataaa aatgcaaaaa aaaaagaaac atcaacacga
      841 aaagcatcgg tgcagtgttt cgtgtcggaa ggatttctgc agtcttaaca aatgtgaata
      901 aaaaaatgaa ttccattact tataagaaac cagaccaaca gtaaaactcc aactcttttt
      961 aaaagttctc cacaaatcac caagcttaac tataaatata ccaaaaaaaa aacgtttttt
     1021 ttctcaaaaa ttgtatctta gaaacagcat gttttgaaac tttcagaaaa ggtttgttag
     1081 taaaatgaaa gctatacgta aggagtgttg tttgatgaaa ttttttcaag agtttttcat
     1141 tattattttc ttttctgtat taggagaagg catacggatt tttgctcatt tacctattcc
     1201 tggaagtatc ttaggtattc tttttttatt tttagcattt gaaatgcatc ttgttgatcc
     1261 tgaaaaaatc ggagcaactg gtgatttttt attgaataat ctagccattt tatttgttcc
     1321 tgctggtgta ggtttattgg aatattttga tgatattgct tcgatatggc ctgttttact
     1381 gggagcagtc gtcgtgtgtt ccatcgtcac gatggttgca gcgggaaaaa cggcagaagg
     1441 tgtagaagct ttgctgggct atgtccgtaa gaaaaaagca gaaagggtat ctgtaaacga
     1501 aatggaggag aatcaaattg actgagtttt ttgtgaatcc attatttggc ttaagtttga
     1561 ctttaggagt gtacgtatta tctgacaaat ttttgcggaa atataaactg cctgttttga
     1621 atcctctcgt attatcgatt gttgttatta tcttattttt gcatttttct gggatcagct
     1681 ataaagacta taatatcggg ggcaattttt tgactatgct gattactcct gcgacagtgg
     1741 cacttgccat ccctctttat aaaaacttcc gtttactgaa agagaatttt tatcctgtaa
     1801 tggctgcgat tttagcagga atagtcgcaa attgcttggt tagtgtaggg ttcggttact
     1861 tcttctctct tcataaagag atggtgatct cattactacc taaatctgta acgacggcta
     1921 tttctgtcga tttatctcat acgatgggcg gggtgaatgc cgtgacactt gctattgttg
     1981 tctctacagg tatttttggt tcgctgatcg ccactcatat tttccgccta ttcaagatcg
     2041 aaagtccagt tgctcgcggt gtggcgttag gaagtacttc tcatgctatt ggtacagcaa
     2101 aagcaatcga gattggtgaa atagaaggaa tcatttccgg acttgcgata tgcgtcaacg
     2161 gaatattgac cgttttattg ctaccgttat tctttcagcc ttttgctggc ttgttttgat
     2221 gcgaaaacca ctattttatg ctacaataac caaaacgttc gagcataaaa aaggagggaa
     2281 agacgtgtat ttgtcttccg agtatcttaa acaatttgat aaagatctat attataagat
     2341 tctcctccta gaaagttttg aggatcaagc ttggcatacc gctgcacaat tagcgcaagt
     2401 tgttcagctg gatgcccgca gcgtgtcgaa atacctgaac gagctgtcta aaaactatca
     2461 gcagtttagc ggtaagacac accctttgtt tacaaaaaat caccgttctg gttataactt
     2521 ttatgatacg ctcgattcaa ttgaacatga gcgttttttg atctatctcg tgcaaagtac
     2581 gctgaaattc cagttgctgc acgacatttt ttttgaagaa ttccatacaa tgtaccaatt
     2641 tgcgcaaaag cattacatta gtgaatctac tgctcatcga aaaatcaatg aatggaaaca
     2701 gcaactgcaa acttacggaa ttcggctgca acgaggtaca tatatcgctc aaggcgaaga
     2761 agaaatcatt cgactttact tgcatatgac attctggcag ttgtttcgag ggaaaatctg
     2821 gccatttgaa acgatttctc aaatggacgt aaagaatatg gcagaacata tcatggcttt
     2881 ttttaatgtt cgtctgaacg agatcaaaaa aagacgattg gaatatatgc taggtgcctt
     2941 ttttttaaga aaatcacaga agcattatgt tgtattgaat gagaaaaaaa gacggctgat
     3001 ttctgacaat ctgttgttcc agcgattttg ccaggtcatg gagccggtat ttcctaatta
     3061 ttttcaagta gaagacgagt taggcgcatt atttcttgta ctgatgactc gtgaagaata
     3121 ttatagtgat cctaagatac ggaagaaaat ttttgatttt catcaacaag caaaaacacc
     3181 gccctttaca gccctttcag aagcaaaagc cgctctttct ctttatcagg aagagcaggg
     3241 gctgccagca gaaaatctaa ccttcgaggc agaaaactat ttattcagca gtcatttttt
     3301 cgcctatctt tttcctaatg cgaaagaaac gattgatggc aatagtagtg attttattaa
     3361 tcatttagtt attgaaaaca aggaattgaa acaatggctc gtacattttt ttgaaagtag
     3421 acacaaacat cccaatcatc tggcatttaa aaatcatgcg tttttgatgg ggcggtatct
     3481 gactgtgttt aaaacattag gagcctttac tccacagctt ccaaagatca cgatcctttt
     3541 aatgacagat ttcccattat ttgaagagca actgttagag gagggattac ggacattttt
     3601 ccgtaatgag tatcagctga tttttctgcc aacagattat cgggggagag aagttgatct
     3661 tctgatttcg acaagtaaag tccaccgcaa accatgggcg gatcttgact attttattgt
     3721 gactgaagaa ctaaaattaa ttgattacat ccaactatct caaaaatttg aaatgattca
     3781 aaaacaaaaa ctattaaaac aataacaaag aaggagaaaa aagatgacat ttgaagaaat
     3841 tttaccagaa ttgaaaaaag gtgcaaagat tattcgtaaa ggatggagtg gatttgaact
     3901 ttatgttgtt ctcgtatccg atgatgaatt tgatggctgt ccggtgacgc cgtacttatt
     3961 gatcaaaaca agtgacgaag gtttttccag cttcgctcct acagtttgtg atattttagc
     4021 agatgattgg gcgatcgtag aatgaaaaac cagtatccag atctagctaa acaggttgta
     4081 tttatcacag gagctgcttc tggaattggt gctgcgcaag cccgagcgtt tcttgaacaa
     4141 gatgcttttg tatttggatt agatcaaaag ttcggtaaaa tggaagaaat ttctttgcga
     4201 tttcctgaaa cttttgccta cgcactaggt gatgttcgac aaatgaaaga actccaacaa
     4261 gcggtatcga aatgccaaaa tcattttggt gaagttacga ttttactgaa tacagcgggg
     4321 atattggatg cctacaaacc cttgatggaa actgacgaat cgctgtggga tctgatttat
     4381 gagacgaatg tgaaaagcat gtatcagctg acaaaaatca tccttcctga tatgatccgc
     4441 caaaaaagcg gaacgatcat caatatggct tcgattgctg gcttgattgc tggtggaggt
     4501 gggatcgctt atacaagcgc gaaacatgcg attgtcggat ttaccaaaca actcgctctg
     4561 gattacgcag gacagggtat ccgagtaaaa ggaattgctc caggagccat ccaaacacca
     4621 atgaatgcgg ctgattttga agggaaaggt gagatggcag agtgggtggc aaatgaaaca
     4681 ccagtcaagc gatgggcaca gccggaagaa gtagctgagc tgacgttatt tcttgcctct
     4741 cctcaagcaa gctacataca aggaacgatc atcccaatcg acggcggatg gttgttaaaa
     4801 taaccttgtg tttttttcaa gcttctgtat gataaaacta aagagagaaa caacggttga
     4861 tgataaaaaa agtcgatgac tgttcccgac attcgatgcc gaacagccag ttcaaaaaat
     4921 tctttttaat aatcgttaat attcgaaact aagcggcttt tcacgacctc ttgatataaa
     4981 cgatattcaa aagcttgcaa ctgcggtaac aagtccagcc aaatgaaaaa tataaggagc
     5041 tatttttatt tgaccattct tattacttgt tgcagggcag ctttttcact accttctgcg
     5101 acacttcagt tggaattttc ttcccatcct ttggtcgcgg tcattaccaa gataaaatta
     5161 tcttgcaaag gagaaataga acatggaaaa aaataatacc cgttcagcca aacgctggac
     5221 aacgacagat gtgactcgga tggcgctagt cactggttta tatgtggcag tgacgctggt
     5281 tttgtctgtc tttagctttg gagtgattca gattcgtctc tcggagatgt tcaactatct
     5341 gtccttgtat aacaaaagat acatcgtcgc ggtaacagcg ggagtagctt tggctaatat
     5401 tgcttctcct cttggactga tagatgttgc agtaggaagc gtcagcacgc tgcttgtatt
     5461 gcttatcaac tataaaatca ctagtcgcat caaaaacatg aaaatcaaaa tggccgtgac
     5521 agcatgcgta tttgcttttt ccatgtttac agtagctggt cagctaacga ttttatatca
     5581 actacctttt ttcttgaatt ggtgggtgat tgctttagga gaattggcat caatgattgt
     5641 cggtgggata attatttatt ggatcggtaa aaaagtggat ttgtcaaaat aaagatctgt
     5701 ttaatttaaa atagggcagc atggaagaga ctgaatgttg agtcttcttc catgctgctt
     5761 ttttgattaa tttgtatgaa gaaatcgatt tagccgtttt ttcatcaaga taccgatata
     5821 agctgctcca gttgccttga ttgcttccgg cagtaaaaac ggcagtagtc cactggcaaa
     5881 tgcagttgta aaagtaagat caccacttat tttcagccag atcgttccgc agatcaatgc
     5941 agcaagagag cccattagat tggcaaagat tgcatataag taatgagcat ccgttctttc
     6001 gatcatccaa ccagttatcc acgtttgtaa gagaaatcca atcaaatatc cgccagttgg
     6061 cccaaataaa acagctatac ctccagtcat ccctgaaaat acaggaagac caatcaagcc
     6121 aagtaaaaga taaactccaa cagatatcaa tcctagtttt cttccgagaa aagttgctgt
     6181 taatccaata gcaaatgttt gccctgtcaa aggaaccaaa ccaaaaggaa tggtcatctg
     6241 agaaaggaca gaaataatcg cggcaaattc cgcagcaagt atcaattctt tcaatgttcg
     6301 gttcataacg ccctcttttc gttaacttaa tatttttatt tggttaacga aattgtaaaa
     6361 caaagtgatt actttgtaaa tagaaaatat aaaaaaagac cagctatcca atagatagcg
     6421 gtctttttca agaaagcttt tgaaattata agctttggtt gtagtattca acgacaagag
     6481 cttcgtcgat ttctggatat agttcgtcac gttctggtaa acgagtcaat gaaccttcca
     6541 atttttcagc gtcaaagctt acgaatgctg ggcgtccaac agttgcttct acagcttctt
     6601 ttactgttac gatgttttgt gatttttcac gaactgagat cacttgaccc acttctacgt
     6661 ggtatgaagg gatatcaacg cgtttgccat caactaaaat gtgaccatgg ttaactaatt
     6721 gacgtgcttg acgacgagtc gttgcaagtc ctaaacggta aacaacattg tctaaacgtt
     6781 gttctagtaa gatcatgaag ttaacaccat gtttaccttc tttgattttg ctagctttta
     6841 cgaacaagtt acggaattga cgttcgttca ttccgtacat gtgacgaagt ttttgttttt
     6901 cagttaattg catgccgtat tctgattgtt tgccacggct attaggtcca tgttgacctg
     6961 gtgcgtaagg gcgacgtgct aattcttttc ctgtgcctga caatgagatg cctaagcgac
     7021 gagaaatttt ccatgatggt cctgtataac gagacattaa aatttcctcc aatgaatata
     7081 agtttttgga gtaaaataat ccgttgaaaa attcataatc atatagtttg ttcttcaatc
     7141 ttcacctttg cagccgcggt tacacaatcg aacccgagac ggggcaacaa actagggatg
     7201 agttattatt tttctgctgc attattttac acaaattaca gtatatgata gatcatccac
     7261 gaatgtcaag ataattagta cataaaaacg ctttacaaac ctaggctgtc tttataaaat
     7321 gagagggtat gtgcaaatgg aaaaaagcga aggaagttta aggagaaaat caatgaatcc
     7381 ggtatcacca ttatttgaga aaatcgatgc ttcaattgaa aagaaggcga atctttttga
     7441 aaacagcttt tcacgttacg ctgttcgagc ggttctcgcc tgtttgtttt tgactttagg
     7501 aacggctgtg gcatttgcga tcgcgatgaa gggggaagat atcgcgcatg gtctaggaaa
     7561 gattttatac gcatttatgt tcagctgggg tctggtcatg attctataca tgaacgccga
     7621 attaggaaca tcgaatatgc tttatatgac cgtgggtgtt tttcggcaga gacttgcttt
     7681 aagtaaggca gccaagattc tatttgcctg tatttttttc aatatgattg gcggtatatt
     7741 atgtggattt ctaatttcta tgactacgcc atttcaagat ttaacgttgg acaactttat
     7801 gttagaatca atagcagtaa aactagcaaa accttcagca acgattttgg tggaagggat
     7861 gtttgcgaat atcgttgtca ataccgctgt actgatcagc atgcggatga aagaggatgt
     7921 cggaaaagtg atcacagtcg tattcatcat tttcattttt gcttttttag gatatgaaca
     7981 cgtgatagcg aattttcctg cctttacgct tacttacttt gcttctcacg gacagatgga
     8041 tggaatgaca gtcagcaatg tgttacataa tttgtttttt gctttggcag gaaattatat
     8101 tggtggcggt ttagtaatgg gactgggata tgcttggctg aatcagtcaa aatcatccta
     8161 tgtggactaa aaagtcgttc attaaagggg aagtgccatg gaagttttag tttttccaaa
     8221 aaatgaggaa aaagcgttac aaatggaaaa gtacatgaaa aatctttttt cctttgctgg
     8281 agtacctaag ccggaacgcg ctcttttaca acaaccgtta ctggatgaga gcaaaaattt
     8341 atctatttct gaagttttag cttttgttca ttattattat gaacaaatcg aaagagagta
     8401 tcagtatgta gcgatcgatt tagtccagaa aaacatcaaa cggcttacat ttgaagactt
     8461 agtcgtattg ttgccactag ttcagaaaaa agaatggtgg gacagcatcg actcttggag
     8521 aaaagtatac agcacatggt gtaaagccta cccagagcag cgtgaagaag tctttcaatt
     8581 gtttgaaaaa aaggaagatt tttggctacg tcgaatagca atcacgttgc aattaggtta
     8641 taaacagcaa acagacacag gactattgat ccgagcaata gacgaagatc gtcaaacaaa
     8701 ggaattcttt atccaaaaag caattggttg ggcattacgc gattatagta agaccgatgc
     8761 cgattgggta aaaagacagc tgacaacaga tttgagtaag ttagctgttc gagaggcaag
     8821 taagtattta taagaaagcg agacgacaag agatgagacg caaattattt gcttttgata
     8881 ttgatggaac gttgttagat tcaaacaaac aagctttaga tagcacaaga gaagcattgg
     8941 aaaaattacg caaagccggt catctggtca cgattgctac agggcggagc cgatttcatg
     9001 cgcaagagat cattcgcgat cttgatttta cgaactacat tttatgtaat ggagcggccg
     9061 gttttttaga ccatgaacaa gtatataaga atttactaga tcgcgaccag ttggatgcgt
     9121 tcgttcaaga agcgcatcat gagcagatcg atacagcttt tgtcagctta gacaatatca
     9181 agcgttcttc ttccaatgat gtaacggtga tggaagaagc gatgcattct ttcggtgctg
     9241 tcttgcctga attagatcag ttttttgcag aggaacaaga aatataccaa gcgttagcat
     9301 ttttcgatca aacatatgat gggaagttct cttcatatga taaaattcga tttgtccgct
     9361 ggcatgagaa cagtgtagat gtcgtaccta aaaatggttc taaagcagcg acaattctgc
     9421 acttagcaga acaagtaggc atccctcatg aagacatcat cagctttggc gatggacaaa
     9481 acgaccgtga aatgttgcgc atgtcaggaa ttgggatagc tatggggaat gctgtgccag
     9541 aagtacaagc agaagctaag atggtcactg atacaaacga tcaggatgga atttggaagg
     9601 cattgaaaga gttaagcgtg atttaaaaga ggttgtgaaa aagctgttct gcatcaagta
     9661 ataagcccag ccaaacaaaa atagctcctc ctatttttcg tttttctggg cttattaccg
     9721 cagatgcaag ctttcgaaca ccgtttaagg aagaggtcgt gacagaagtg gtcagtttca
     9781 agaaataaga agggatttac gaaaattgct tctcaaattt ttgtaaaatt acggcttatt
     9841 tctgaagaag tagatgaaac aacgtttatt cgggaaatgg gactgtgaca agatgtttgt
     9901 catagtccca tttttttatt ttatttttca aaactaagaa ataccaggaa agagttcctt
     9961 ttgtttgacc ttttctttct tattgaaaac aactataata tagagtgatg ttaaaagaga
    10021 agaggaattt agtgtgcggg tattgtttat tggtgatgta gtaggttcaa tgggacgaga
    10081 gatgattact gaatatcttc ctagattgaa gaagaagtac cgtccgcaag taacgattgt
    10141 aaatggtgag aatgccgctt ctggacgtgg aatcacagaa aaaatctata aaaaattttt
    10201 gcaagacggc gtagatgtcg tgacgatggg gaatcatacg tgggacaacc gcggaatctt
    10261 tgagtttgta aatgaagcta aaaagatggt tcgtccggca aattttccgg aagggacgcc
    10321 tggacaaggg atggtctttg tcaaagtgaa ccaagtcgaa ctggcagtga tcaacatgca
    10381 ggctcgttct tttatggtgg acttggatga tccttttcgt aaaatgaatg agctggtaga
    10441 agaagccaga aaacgtacgc cgatcatttt tgtagatttt catggagaaa caacaagtga
    10501 aaaacaagca atgggctggt ttttagatgg gaaagtttca gcagtggtcg gtacacatac
    10561 acacgttcag acaaatgatg cgcgaatttt gccaagagga acagcgtatc tgacagacgt
    10621 tgggatgaca ggtccctatg atggtatttt gggtatgcgc agagaacctg taatcgaaaa
    10681 gtttctgact gcattaccaa aacgttttga agttgtggaa caaggccgat cgattttaag
    10741 cggctgtatc ttggaattgg atgatacgac aggtcatgca aaagaaatcc agctgattca
    10801 gatcaacgat gatcgaccgt tcatggagta gaaagagagg cagttttttg cagcaggagc
    10861 cggaaattca aaaagaagta aggaaactga caaaactttt aagagagaat gaaacgatca
    10921 ttcgctacaa agaacttgaa gaaaagatcc agcaaaacca gtatttagct gagttgagag
    10981 aaaaaatcaa acaagcgcaa aaagatgctg ttcattttgc ccactatgac aaaccagcag
    11041 cagaaaaaga agcaatcaaa caagcggatc aattcatgca agaatttgat cagcatccgc
    11101 ttgttgtagc ttatagaaaa cagctgttgg aagcagatga tctgcttcat catttaacaa
    11161 ctatgataca agaagaaatc aatggacaaa tagaggagga aaaacatgcc tcaaaaaact
    11221 aaaaatactc ctatgatgga acaatatcta agcatcaagg cccaatacca agatgctttt
    11281 ttgttctatc gtttaggaga cttttatgaa ctattttacg aagatgcgat caaagcgtca
    11341 cagcttttgg aattaacgtt gacgagcaga aatcgaaatg cagaagaacc tattcctatg
    11401 tgcggtgtac ctcaccatgc agcacaagga tatatcgatg ccttgattga aaaaggctat
    11461 aaagtagcga tttgcgagca ggtagaagat ccaaagacga ctaaagggat ggtcaagcgc
    11521 gaagtgatcc agctagtcac tcctggtaca gtcatggaca gcaaaggatt gtcggcaaaa
    11581 gacaacaatt ttttaacagc tgtagttagt caaggaaatg aatttggctt tgcttatgcc
    11641 gatttaagta cgggagaatt gaagacggct cggttgcatg atgaagaagc tgttttaaat
    11701 gaagcctctg cattgcagac aaaagaactc gtattaggca gtgagatcac tgataccctt
    11761 cgtgaacagc taagcgggcg tttagggcta gtcttttctc aacaaaatga gatggaagaa
    11821 aacgcggaat ttagcttttt gacaagcgaa ctagtcgatc cgctggaaaa agaagcaacc
    11881 ggcaaactat tgacttattt atcggtgaca caaaagcgga gtttagctca tatccaaaaa
    11941 gcagtagaat accaaccaga tcattttttg aaaatggatt attattcaaa attcaaccta
    12001 gaattaagcc aatctattcg gactgggaaa aagcacggca ctcttctatg gttgttagat
    12061 gaaacaaaaa cagcaatggg tggccgttta ctaaaacaat ggctagaccg tccgcttatc
    12121 caggcaaaac aaattaaagc aagacaagaa atggtcgctt ctttgctaga cagctatttt
    12181 gaacgtatcg atttgcagtc agcattaacg aaagtctatg atctggaacg cctagcaggt
    12241 cgagtagctt tcggtaatgt caatgggcga gacttgatcc agctgaaaac ttctttagaa
    12301 caagtgccaa tgatcagagg gttgattgaa ggaatcgatc aaggtcaatg gcaaagtctg
    12361 ctttcagaaa tgcagccgat ggaccatctc gtccaattga tcgaccaagc tatccaagat
    12421 gatccgccgt tacaaataac ggaaggaaac atcatcaaag atggattcaa tgagcagctc
    12481 gatatgtacc gttctgctat gagaaacgga aagaaatggt tggcagaact tgaagcaaaa
    12541 gagcgtcaag aaacaggaat caagaactta aaaatcggat ttaaccgcgt tttcggttat
    12601 tatatagaaa ttacaaaagc aaatcttgga aatgcagaac tggagaagta tgaacgaaaa
    12661 caaactttag caaatgcaga gcgtttcatc acaccagaac taaaagaatt ggagacacaa
    12721 atcctcgaag cagaagaaaa atctgttgat ttagaatatc agttgttttt agctgtgaga
    12781 gaagaagtca aaaaggctat ccagccgcta caagtacttg caaaagcaat cagtgcagta
    12841 gatgtgctac aaagttttgc aacgatcagc gaacgctatc agtatgttcg gccagaactt
    12901 gtcagtgaca agcatcagct tctgatcaaa gacggacgac atcctgtagt agaaaaagta
    12961 ttaggacatc aggaatatat ccctaacagc gtagaaatgg cagaagacga aatgatcttg
    13021 ctgattacag gaccgaatat gtctggtaaa agtacgtata tgcgacagtt ggcattaact
    13081 gttctgatgg cgcaaatggg ctgtttcgtt ccggcaaaac aagcagtttt acctattttt
    13141 gatcggattt ttacccgaat tggtgcaagt gacgacttaa ttgctggaca aagtactttt
    13201 atggtagaga tgatggaagc caatcaagcc ctgcgttatg ctacgccaaa cagtttgatt
    13261 ttgtttgacg aactagggcg aggaacagca acctatgacg gaatggcgtt ggcccaagca
    13321 atcatcgaat atatccatcg tcatgtacaa gcaaaaacac tcttttctac tcattatcat
    13381 gaactgacgg tacttgagaa agaacttccg cagcttaaaa atgtccatgt tggagccgtt
    13441 gaaaaagacg gagaagttgt cttcttgcat aaaatgatgg atggacctgc ggataaaagc
    13501 tacggcatac atgtggcaaa gatcgcagga ttgccttcca atctactaga acgagcagca
    13561 gatatcctgc atacgctaga aaatggcgat aacggacacc atactgttcc agctgaagta
    13621 gaagagaaaa ctaaaacagc caaacaggag caaataaaac cacctgcaga aaaagtaaat
    13681 caagaccata tacaagaccg tgtaaaagaa gaaaaccaac agctttcttt attcagtgaa
    13741 ttatccgaaa atgaaacaga agtcattgaa tcactgaagc aaataaattt actagaaatg
    13801 acgccaatgg atgcactaaa cacattatat gaattacaaa aacaactgta ggaagaaggc
    13861 ggatatcgat ggccaaaatc caagaattat ctgaacgttt agctaatcag atcgctgcgg
    13921 gagaagtagt ggagcgacca gcttccgttg tgaaagaatt agtggaaaat gcaattgacg
    13981 ccggcagtac tcagattgat atcttagttg aagaagcggg actgcggacg atccaagtga
    14041 ttgataacgg agaaggcatt ttggcagacg acgtagagaa tgccttcaag cggcatgcga
    14101 caagtaagat ccataatcgc gacgatcttt ttcgcatacg aacgctgggc tttcgagggg
    14161 aagctttgcc aagtattgcc tctgtttctg aaatgactct ggaaacggcg aatcaggaag
    14221 aaaaacaagg cacctatctg tcgctgaaag gcggagaagt tattgagcat cgaccagcac
    14281 cactgcgtca aggaacgaag attaccgtca gcaatctgtt tttcaatacg ccagcccgct
    14341 tgaaatacgt gaaaacactg cacacagaat tagcgaacat cggggacatc gtcaatcgac
    14401 tggcattgag tcatccatcg attgcttttc gtttagtaca tgatggaaac aaaatgctgg
    14461 caactgctgg aaatggcgat ctgaaacaaa caattgcggg aatctacgga ttatctaccg
    14521 caaaaaaaat gctgaaaatc gaaggaaaag atctagattt tgagttattt ggctatgttt
    14581 cattgcctga ggtgactcgt gccagtagga attacttatc gacgatcatc aatggacgtt
    14641 ttatcaagaa cttttccttg aataaagcaa tcgttgcagg ttatgggtca aaattaatgg
    14701 tcggtcgttt ccctattgct gtattggaaa tcaaaatgga cccgctttta gtagatgtaa
    14761 atgttcatcc gacgaagcag gaagtccggc tgtcgaagga aaaagaacta acagagctaa
    14821 ttagtaacgc cattcaaaaa gcattgtctc aagaaaatct gattccaagt gcagcggata
    14881 atctacggtt taagaaaaaa gtacctgatc agcctaaaac agaacaaatc gaaatcgatt
    14941 tgtcctacgc ttttgaagaa gaaaaaccta aaaagccaag tagtttgaat tttgatcgac
    15001 agacaggtac ctttttcgta gaagaactaa agaacacatt tgttgacaga attgttgata
    15061 agtctgtgga aaatgttgaa aactattctg gtttttctga agaaaacacc acttatccag
    15121 aaaaaacagc gaaaacggtg gataagtttg gtgaaaatgt tgataacttt gtagaaaaaa
    15181 cagtggaaaa atctgaaaag aaagaatttc ccattgtgga taacatggag aaaacaaatg
    15241 aagaacaagc agataaatcc gtagaagagg atgaaaagat ttacgaggaa gaattgacac
    15301 tccatcctga atttgatttc actcaaggaa acgacaaaac attagaacaa gccatcaaga
    15361 aattagaaac ggaaaaacca gtacaacgtt ttcctcagtt ggaatatttt ggacagatgc
    15421 acggaacgta tctttttgcc caaagtagcg atgggttgta catcattgat cagcatgctg
    15481 cccaagagcg cattaagtat gaatatttcc gggaaaaaat tggggaagta tctgatgatc
    15541 tgcaagaatt gcttgttcca tttgtgttag actatccaaa cagtgatgct ttgaaattaa
    15601 aagagcaaaa acacttgcta gaagatgcag ggatttattt agaagaattt ggtcaaaaca
    15661 gctttattgt acgggcccat cctacttggt atcccaatgg agaagaagaa tcgattattc
    15721 gggagatgat cgatatgctg ctgacaactg gaagtgtgag tgtaaaaaaa ttccgtgaag
    15781 caacagcaat catgatgagt tgcaaacgat cgattaaagc caaccattat ttgaatgaag
    15841 cacaagcacg tgtgctgctg aaggatctgg cacgatgcga aaatcctttc aattgtcccc
    15901 atggccgtcc agtattgatt cactttacca attcggatat ggaaaggatg ttcaaacgaa
    15961 tccaagaccc gcattaagtc aaagagaaga gggaaaacat gaagattgta ttagcatccc
    16021 aatcaccaag aagaaaagag ttattggctc atatcgtttc agaattcgag attgaacctg
    16081 ctgatatcga tgaaacgcca tttccagacg aacagcccgt cgattatgtt cgtagaatgg
    16141 ctgaagaaaa agcacgaact gtctgggaac aagatgaaaa agaagaccat ttagtgattg
    16201 ccagtgacac gactgttgtt ctcaatcaag agatcatggg taaaccagaa gatctggctg
    16261 aggctgaatt catgctgaaa aaactaagcg gggaaacaca tactgtatat acagctgttg
    16321 ttttaaaaac aaaggaacga gaagaacgga tactagcaga agcacatgtc actttttatc
    16381 ctttgacaga cgaagagatc aaacgctact tggagacggg ggattatgcg gataaggcag
    16441 gggcatacgg catccaaaat gctgcgagtg tattcgtcaa agaaatttct ggagattatt
    16501 acagtatcgt aggatttccg attggtgctg tcaatcaggc actgaaaaca ttcatttaaa
    16561 caaaaaagcg gactatctga ttttcgattg aaaatccatg atagcccgtt ttttttattg
    16621 aaaagattac ttatctactc tgactaagat tttacttcag ctttaccgac tgcttcgccc
    16681 gggcgaacaa gtcctgattg gtcaagagaa agtcctgcaa ctttttcatt attggtcaaa
    16741 gcaacaataa tgtcagtttt cttgccagct tgttctattt ctggcaaatc catttcagca
    16801 atcagggtct ctggtgtgac aaggtatcct tctttcacga atacattgaa aggaacaccc
    16861 tttagttcaa cagtatctaa tcccatgtga acaagtactt ccagcccctc attagaaaga
    16921 ataccaatgg catgttttgt ttcaaagaca ctcgtcactt taccgtttac tggtgcatag
    16981 actttgccgt ttgacggttc gacagcataa ccgtcaccca tcattttttg tgagaaaact
    17041 gggtcattta cttcagttat ttccttgatg gtccctgcag cgactgcgaa taatgtttct
    17101 tttgttgcaa ctgccgtacc agttgctgaa acaggttcga aagactgtgg cgttgctgtt
    17161 gcgccatttg ctgtttgaag ttgtacatca gcagcatttt caggaacagc aggatcaatc
    17221 ttattcaaaa ttccctgacg tctaaagatg atcgtcaagc caaatggaat gatgacagca
    17281 atgatcattg cgatgatgaa aggtacccat gtttctgctt ggatagctag tattcctggc
    17341 aaaccgccta ctccgatcgc gttagctcga acacccatca agttagcaaa catgccagct
    17401 aatccagagc cgaccattgc agcgacgaaa ggatagacgt atttcaaatt gattccgaac
    17461 atagcaggtt cagttacgcc taagtaacaa gaaatcattg ctggaatcga gatttgttct
    17521 tcttttttat tcccacgatg taagaagatg atggctaaga ctgcagagcc ttgggcgata
    17581 tttgataaag caatcatcgg ccataaattc gttgatccga aatctgcaat cagctgcata
    17641 tcgatggcat tggtcatatg gtggagacca gtaatcacta aaggagcata caggaatccg
    17701 aatacggcac taaacaacca gctgatagaa gacgtcaatc cagtatttac gatatttgag
    17761 atccagcttc cgactgtcca gccgatagga cctaaaataa cgtgtgcagc taaaacagtt
    17821 ggtaacaatg aaaacaatgg aacaaaaatc atcgagatcg actgagggat atatttgcgg
    17881 aagaagattt ctagatacgc taacataaac cctgccagca tggctggaat aacttgcgct
    17941 tgataaccaa tcatctggac ttgagcaaaa ccaaaatccc aaaatggaat atctgctgcg
    18001 gctgtggaag ctacactata agcatttaat aattgcggag aaactaacgt aattcctaaa
    18061 acgattccta atatttgtgt agtacccatc ttttttgcaa tactccaagt gatacctact
    18121 ggaagaaaat ggaaaattgc ttcaccgggt aaccacaaaa aggcattgac accattccaa
    18181 aacttcgagt gttcaacgat tgttccacca agactttcaa actggatacc ttcaagtaca
    18241 tttctgaatc caaggatcaa tccaccgaca atgattgcag gaatcagtgg tgtaaagatt
    18301 tctgctaaaa cggcaatagc acgttgaacg ggatgaaggt tttgttttgc agctgctttt
    18361 ccttgttctt tggaaacccc ttcaactcca gatactgcaa cgaagtcgtt ataaaaagta
    18421 gaaacatcgt ttcctatgat gacttggaac tgtcctgcat tcgtgaacat cccttttacg
    18481 ctaggtatat cttcgatcgc tttttcgtcc gcttttcctg gatcattcag gacaaaacgc
    18541 atacgagtcg cacaatgact aactgcagca atattttctt ttccgccgat atcatgtaac
    18601 agcttctcgg catctgcttg atattttgcc atatcaataa acccctttct cttaacttgt
    18661 ctatgcaagt tgtttcttca tttactatac tttttttcgg agagaattgc aagcgtttta
    18721 ttaaaaagta cgagagaaaa tgatatcgtt ttaaaaagct taaaataagc ttttcttaaa
    18781 aataggaaca ttgaaataca aaaagagctg tagtatagtg aagaaatgat ggaagaacga
    18841 gtgagggaaa aaacatgaat aagttcaatg aaattttttt agatttggaa cagaaaattt
    18901 tagcgaaaga atatcctccg cattcgcttt tacccagtga gaaccaattg atcaaaattt
    18961 atggtgtttc acgagaaaca attagaaaag cgctgaatct tttgactacg gaaggttata
    19021 ttcaaaaaaa acaaggaaaa ggttcgatcg tactggatcg gaatcgcttc gactttccta
    19081 tttctggatt gactagctat aaagagctac aggagaccca acgtattcca agtgaaacga
    19141 tcatccatac gttagaagaa acagaagtga caaaagcatt gaacgagatc actggctggg
    19201 agatcggtgc gcctgtttgg catttgatac gcgaaagaaa aatcaatggc gaagtagtta
    19261 tattagacac cgattatcta ttaaaggaaa tcgttcctat tttaactcca gcacaagcac
    19321 aaggatcgat ctatgaatat tttgaaaatg agctttcttt gacgattgct tacgcgcaaa
    19381 aggagatcac agtagaagaa gtaacggaaa tcatgaaaac agcgatggat cttcacgatg
    19441 acacttatgc agtagtagtc agaagcctcg ttcatctgga agatacccgc tgtttcgagt
    19501 attctgagtc ggttcaccga ttagataaat tccgtttcgt tgagtttgcc cgacgccgaa
    19561 aagtgtaaat agttcaaaag aaagcaaatt gttggcatct gtccactttg gcgctatgat
    19621 aggatcacaa agggggcatt tttaatggat aaaccaataa gaccagaaaa agaagaactg
    19681 aaagaaaagt tatcacccat ggcttatgca gtcacacaag aaaatgcaac agaacgacca
    19741 tttagcggga aatatgatga tttttacgaa aaggggatct atgtagatat cgtcagcggt
    19801 gaaccgttat tcagctctgc agaaaaatat gatgcaggtt gtggctggcc atcattcagc
    19861 aaaccaataa cgaaaagaca agtgcgcgaa aaagccgatt tttctcatgg catgcatcga
    19921 atagaagttc gaagcaaaga agcagattct catctcggac atgtgtttac cgatggacca
    19981 gtagatcaag gtggtctacg ttactgcatc aattctgcct cactgaaatt cattccatat
    20041 gaaaagatgg atgaattagg ttatggggaa ttcaaatcac ttgtagaata atggaaatac
    20101 acaaagagcg gtacaatacg gggatttact cgatcgtccg ctcttttttt attcaagcga
    20161 ttgctatttg aaagaaacgc tccctagact cctttttttc acaaggtgaa atgtgctaca
    20221 ataaagggaa cgtatgtgtg caaaagaaag aggactagaa tatgtatgaa tatctgacag
    20281 gtgtggttac ctttatcaac ccctattaca tagtagtaga aaccaatggt atcggctacc
    20341 agatcgcact aggaaatcct taccgctaca gtagcaaact aaatcaaaaa ataaaaattt
    20401 atgtccatca ggtaatacgt gaagatgcgc atcttctgta tggatttgat tcgctagaag
    20461 aaaagcaact gtttttgcga ttagtaagtg tttcaggaat cggtccgaaa agtgcccttg
    20521 caatcatggc aagcgaagac cactccggtt tgattcaagc agtagaatcc agtgatgtca
    20581 cttatttgac gaaatttcca ggagtaggga aaaagacagc acaacaaatg atcttggatc
    20641 taaaaggaaa attcggtgag ctgagtatcg atacaccttt tagtctattt gatgaagcaa
    20701 acacaaaaga cgctacagct ctatctgaag caatggaagc tctctcggct cttggttaca
    20761 gtgatcgaga aatcaaacgt gtagaaaaac aattaaaaga agtagataat cagacaacgg
    20821 atgagtatct acgccaagca ctcaagctaa tgatgaaaaa ataaggagga gaccaaatga
    20881 cagatgaata cttgttatca ccagaatctg gcgaaaatga actgagtttg gaaaaatctc
    20941 ttcgaccaca gctgctttct caatatatcg gacagagaaa agtcaaacaa gaacttcaga
    21001 tttacatcga agctgccaga aatcgggaag aacctttaga tcatgttctg ttgtacgggc
    21061 ctcctggatt aggaaaaacg acgatggcca tggtcattgc taatgagatg accgtaaata
    21121 ttcgtacgac gagtggccct gctatcgaac gtccgggtga cttagtagca atcttgaatg
    21181 aactggaagc aggggatgtc ctgtttatcg atgagatcca tcgattacct agagtggtag
    21241 aagagatgct ttattcagct atggaagatt tctatgtaga tatcatggta ggacaagggc
    21301 caaccgcaca tccggttcat ttccctcttc ctccctttac tttgattggc gcgacgacac
    21361 gggcaggtat gctttctgca cctttacgag atcgatttgg catcatttct catatggaat
    21421 attatgacga acaggatctg caggagatcg ttttacgttc ttcggatatt tttcaaacag
    21481 agatcattga agaaggggca ttggaaattg ctcgccgatc acgaggaacg cctagaatcg
    21541 ctaatcgctt gctcaaacgg gttcgtgatt ttgcgcaagt ccaaggagac gggaaaatcg
    21601 atcgtcctat agcggatcag gcacttactt tgctacaggt cgatcaggct ggattggatt
    21661 atgttgacca gaaattgttg cgaacaatga tcgagttata tggcggcgga ccagtagggt
    21721 taagtacgct ttcagtaaac ataggagaag agcgtgagac ggtagaagat atgtatgaac
    21781 cgtatctgat ccaaaaagga tttttaaagc gtacacctag agggcgaatt gctactgctt
    21841 atgcctatga acattttggt tacgactatc atatatgatt tttgctttta gattggagga
    21901 aaatgaatga gtgatacaac acgtacgaaa caattgatca aaaacgtatt gattgatttg
    21961 tgccaaacgc aatcttttcg aaaaatcagc gtccaaaaaa tcgcaaacga agcaaaaatc
    22021 aatcgacaaa cattttatta tcattttaca gataaatacg atttgcttcg ttgggtctat
    22081 tgtgaggatg cattgcatta tttagatcca caatgtcttt cacttgataa ttgggaagag
    22141 caagcattga aaatgctgaa agcaattgct gagaagaaag aattttatgc aaatactgtg
    22201 ctttctgacc cagaaatttt acaaaaagag ttttctcaac tgatccaaaa atcatttatc
    22261 aagatttttg aacaaatgga tgaagaaaga caactttctg caagagacaa actattttat
    22321 gctcgttttt tttcttacgg ttgcagtggt gtattagtca attggatcac gaatgaatat
    22381 gaagaaacac cgatggaaat cgctatgcag cttttccgtt tagccaagga tacggaatta
    22441 tattcttatc gtctttatgc aaaagaagag ttggaagaac agtaatagaa aaattttttg
    22501 ttggaaaagc aataatcgct aaaaggagat ggggaaatga caaaaatttt atttgtttgt
    22561 ttgggaaata tttgccgttc accgatggca gaaggcttgc tgagaaaacg aatagcatta
    22621 gaaggaaggg aagcagaatt ttttgtggat tctgctgcta caagcacgta tgaagttgga
    22681 aagacaccgc accctggaac gaaaaaaata ttaaaccaag aaaaagtaga tatgacgaat
    22741 atggttgctc ggcaaatcac accccacgat tttgaaactt ttgattggat cattggcatg
    22801 gatcaagaaa atgtagaaga actgaaacga agagcaccac gctcagcgca ggggaaaatc
    22861 catttgtttt taagtagcat tcctggaaaa gaaaaagaaa atgttcccga cccatactat
    22921 accaataact ttgatgagac atatcacttg atcacagaag gcctgaatca ttggtggaat
    22981 atttggattg atgaaaataa aataacaaac aatttgtaaa gttaacgctt tctttttaag
    23041 gcgatgttag agcatttcct tgtttttttg taaaatgtta ggtaaaataa aattaattaa
    23101 gtaacacttt cttagctaaa ggaggagtgc attcgatgaa cgaagagaca gtatcgccaa
    23161 tgaagaagct tacgaagtta gttactcata cttcgtatca actttttgat tcttttgtaa
    23221 atgacactga agaacatgct aagaatgtac gattgcaagg aaagtttatt cttgagctgc
    23281 aaaaagctgc tactgaacat agtctagtta tcttacaagt aagagcaaat cgtttgagta
    23341 gcaagtatga aacgatctca ggctgggtgg cgacaaaaac ggtcgaaaaa gaccgagtga
    23401 tgatccgcct acaaaacgaa gagcagcaga tccggatggt tcctgtagaa caaattgaaa
    23461 aaataacaat cctttcacca gcaggggaac aggaacggtt atcaaaataa tttataccag
    23521 atagaaaagc acgtatgagc ttgtaccatc aatcattact aatcaaaaat aaccgaatgc
    23581 tttaagctga tatcagtaaa acggaacgtt ttaggatgag tatcatagca tgacagcatt
    23641 cggttgatta gttgaatcga ttggatggta caagtttttt tgataaaaaa aggtcctgct
    23701 agccggggag ctagcaggat aaggagttaa aaatgaaaaa gtgttgttag ggttgtttgt
    23761 tggtatgctt atataatagt cattagttgt gaatattttg tgacgaaagt tttcgaaagt
    23821 tgttaagttt t
//
LOCUS       DADGKS010000041        23649 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.041, whole genome shotgun sequence.
ACCESSION   DADGKS010000041 DADGKS010000000
VERSION     DADGKS010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23649)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23649)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23649
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.041"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(26..601)
                     /locus_tag="JXV47_001720"
     CDS             complement(26..601)
                     /locus_tag="JXV47_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAX1487765.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(606..1580)
                     /locus_tag="JXV47_001721"
     CDS             complement(606..1580)
                     /locus_tag="JXV47_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleosidase"
                     /protein_id="HAX1487766.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIASALKVNPNIGKHMERFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEEAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(1604..1648)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1863..2831
                     /locus_tag="JXV47_001722"
     CDS             1863..2831
                     /locus_tag="JXV47_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAX1487767.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            2928..3221
                     /locus_tag="JXV47_001723"
     CDS             2928..3221
                     /locus_tag="JXV47_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAX1487768.1"
                     /translation="MRSAAYGNQRRKNRLALFNDEQQEIGEMTWSDAGPDIMIVDHTF
                     VDPAYRGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            3339..3575
                     /gene="secG"
                     /locus_tag="JXV47_001724"
     CDS             3339..3575
                     /gene="secG"
                     /locus_tag="JXV47_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HAX1487769.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3687..4433
                     /locus_tag="JXV47_001725"
     CDS             3687..4433
                     /locus_tag="JXV47_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAX1487770.1"
                     /translation="MRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKADYTV
                     YAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFAVRA
                     LEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSLAEQ
                     QLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQWYPE
                     SGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            4436..6793
                     /gene="rnr"
                     /locus_tag="JXV47_001726"
     CDS             4436..6793
                     /gene="rnr"
                     /locus_tag="JXV47_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HAX1487771.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            6815..7279
                     /gene="smpB"
                     /locus_tag="JXV47_001727"
     CDS             6815..7279
                     /gene="smpB"
                     /locus_tag="JXV47_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HAX1487772.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            7581..8300
                     /gene="atpB"
                     /locus_tag="JXV47_001728"
     CDS             7581..8300
                     /gene="atpB"
                     /locus_tag="JXV47_001728"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HAX1487773.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            8353..8568
                     /gene="atpE"
                     /locus_tag="JXV47_001729"
     CDS             8353..8568
                     /gene="atpE"
                     /locus_tag="JXV47_001729"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HAX1487774.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            8659..9183
                     /gene="atpF"
                     /locus_tag="JXV47_001730"
     CDS             8659..9183
                     /gene="atpF"
                     /locus_tag="JXV47_001730"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HAX1487775.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            9170..9712
                     /locus_tag="JXV47_001731"
     CDS             9170..9712
                     /locus_tag="JXV47_001731"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HAX1487776.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9735..11291
                     /locus_tag="JXV47_001732"
     CDS             9735..11291
                     /locus_tag="JXV47_001732"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HAX1487777.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            11305..12207
                     /locus_tag="JXV47_001733"
     CDS             11305..12207
                     /locus_tag="JXV47_001733"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HAX1487778.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            12230..13636
                     /gene="atpD"
                     /locus_tag="JXV47_001734"
     CDS             12230..13636
                     /gene="atpD"
                     /locus_tag="JXV47_001734"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HAX1487779.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            13650..14072
                     /locus_tag="JXV47_001735"
     CDS             13650..14072
                     /locus_tag="JXV47_001735"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HAX1487780.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            14541..14771
                     /locus_tag="JXV47_001736"
     CDS             14541..14771
                     /locus_tag="JXV47_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HAX1487781.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            14868..16169
                     /gene="murA"
                     /locus_tag="JXV47_001737"
     CDS             14868..16169
                     /gene="murA"
                     /locus_tag="JXV47_001737"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAX1487782.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            16182..16358
                     /locus_tag="JXV47_001738"
     CDS             16182..16358
                     /locus_tag="JXV47_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAX1487783.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            16493..16789
                     /gene="yidD"
                     /locus_tag="JXV47_001739"
     CDS             16493..16789
                     /gene="yidD"
                     /locus_tag="JXV47_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HAX1487784.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            16853..17320
                     /locus_tag="JXV47_001740"
     CDS             16853..17320
                     /locus_tag="JXV47_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1487785.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            17405..18289
                     /locus_tag="JXV47_001741"
     CDS             17405..18289
                     /locus_tag="JXV47_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAX1487786.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLIGAAANYLAVRQGEN"
     gene            18406..18639
                     /locus_tag="JXV47_001742"
     CDS             18406..18639
                     /locus_tag="JXV47_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HAX1487787.1"
                     /translation="MSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYGP
                     KEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            18727..18807
                     /locus_tag="JXV47_001743"
     tRNA            18727..18807
                     /locus_tag="JXV47_001743"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18761..18763,aa:Tyr,seq:gta)
     gene            18814..18885
                     /locus_tag="JXV47_001744"
     tRNA            18814..18885
                     /locus_tag="JXV47_001744"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18846..18848,aa:Gln,seq:ttg)
     gene            19401..20108
                     /locus_tag="JXV47_001745"
     CDS             19401..20108
                     /locus_tag="JXV47_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAX1487788.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRRDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(20167..20811)
                     /locus_tag="JXV47_001746"
     CDS             complement(20167..20811)
                     /locus_tag="JXV47_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HAX1487789.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKNFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSANHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            20938..21225
                     /locus_tag="JXV47_001747"
     CDS             20938..21225
                     /locus_tag="JXV47_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487790.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            21333..21653
                     /locus_tag="JXV47_001748"
     CDS             21333..21653
                     /locus_tag="JXV47_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAX1487791.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIA
                     LIGE"
     gene            21971..23047
                     /locus_tag="JXV47_001749"
     CDS             21971..23047
                     /locus_tag="JXV47_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAX1487792.1"
                     /translation="MFDQPEAKPREVVFFWTGQLTEKQTEIAKRILCHSEKRHHLIWA
                     VTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNELFLRYRYVFPEEKITLLHGNTA
                     TAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYNGDAGLAHAVQTAIRSNGRFIY
                     LSATPDEKLLKEIKQTFELHKLALRFHRRLLPEPVLVFMNNWRQKCGNKKKINSLVRI
                     IQQLIKENRILLFCPSITMMHRLKITLQEAFPEYEITDVSSQDDQRAKKVQKMREAIY
                     EILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQIAGRADRKGPYTNSRVYFFYE
                     EKTSAIRKACQEIKEMNEEGKQML"
     gene            23044..23649
                     /locus_tag="JXV47_001750"
                     /pseudo
     CDS             23044..23649
                     /locus_tag="JXV47_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
BASE COUNT         7816 a         4125 c         5092 g         6616 t
ORIGIN      
        1 attttgctaa tccagctctg tttattcagc ctatttttct ttttgaatat atcaagcgtt
       61 gtggcaacat agtgatgact aatgaaacaa cgacgataga caacaaacga tcaaggtagt
      121 ctgtacctgc ctgtaccaag atcacacttg ttgtctgact taaacctaac ccatgtaata
      181 gctgaacgat catactggat cctgaggagg tgatcccgcc aaataactga acggtaatga
      241 tcgaagaaac gatcgttcca ggtaccgaca aaatcaaagc gagtaataac agtttcaagc
      301 tgtttttatc tttgccgaga tatcttggca aaatcaatcc agcaagcaag cctgtgagaa
      361 tttggattgg cgaataatac agagaaaaaa tatctgtagt cactccactt aaaataccgc
      421 tggacaatcc tgtcagcatt ccaggtacag gcccaagcaa tgcaccagca aaaatcgttc
      481 cgatagaatc gagatagatt ggcaaacgaa gccataaagc aatcgttcct ccaatataat
      541 tgatcccaat acacaaagcc atcactgtaa gtacgcgagt tgccattttg tttttattca
      601 ttttgttagc ccatctttaa cctttccaaa tctttcataa tcgtttcttc ttgtgcattt
      661 aaaagaacgg ttaaaaactt tcggaaaaaa agacgagtat ctacttttgt cataatttta
      721 ctgttagcag gtttctgcca aaattcataa cgatcaacca atgtttgtcc acgacttatt
      781 ccttgagttt ccacagcagt gaagcttttg aaaccttcac agatggcctc ctcgataaaa
      841 taagcaacag ctaacggatc attgatgaca catcctaaaa ttctttcttg tttccagtgg
      901 aagtcaaaat aaaaacgagt gatcgctttt agatactctc cctcttcagg attcatttga
      961 cagcagtatt cgaggatagt cggtgtcaag acgatttctc ttgtcacatc taacccaacc
     1021 atttctatcg tttgtttgag attctcgaat acataagaag ctgcttcagg atcacaccag
     1081 taattgtatt cagcaactgg cgaacagtta ccatggcttt tgtaagttcc acccatcgag
     1141 acaaaacgtt ccatatgttt cccaatattt gggttgactt tcaaagcaga agcgatattg
     1201 gtcaaaggac ccaaagcaat gactgatgta tttgtctttt ctttgaaata atcagccaaa
     1261 aaatcaacgg catggagagg ttctgcctgt tttctcaaga tcatcgggaa atttgtttcc
     1321 cctaaaccat ccataccatg agtgtcttgt gcactgatga aaggttgctt caaaggtttt
     1381 tccattcctt gataaacagg aatgtctaaa cgatcacagc gttccaggca tttcagcaca
     1441 ttctgcgtac ctatatctgc agggacattc ccacaaacta cggtaatagc aactacttcg
     1501 atatcagggg atttgacagc taatgataaa gctaaagtgt cgtcgatccc tggatcgcaa
     1561 tcaataatta cttttcgcat tatttccaat ctcctttctt tagagatact tagtttttta
     1621 ttctgggaag tttccgaacc agtccaagac gagcgtcttg attataatgc acgaaattag
     1681 tatactggct tttattgcga atgtaaatgc tctcttacaa gtaaatctat tgaggagaac
     1741 tttaagtaaa tgatacaatg aaaaagaaat ggaatttacg tgtgccgaaa ataaagaatc
     1801 ctatggatcg gtacattgga taatagatag attatagttt ggcagaaagc ggcgggtgta
     1861 caatggttat tttttatttc attcttattc tgataattat agggatcagt taccattttc
     1921 tttcttattt ttatgcaaag aaattagtaa gagcgggagt acagagagga tatgactggt
     1981 atgaagacac tggtcatcgt ttgatggacc ctgctgcagt cacgtcagta gaaaaaaaac
     2041 gacaaaaatt agaagaagag tgtgaaagct tttgggagca gggaacaccc aaaacaatca
     2101 aaagttatga cgggttgaaa ctagctggtc agatgttcat ccatccaaat aagcagaata
     2161 aatgggtcat ttgcgtacat gattaccgaa gcacagggaa aagagacatg tctcatatag
     2221 gtaaaagata tgcagagaaa ggattcaacg ttcttgtacc tgatttacgt gcgcacggag
     2281 aaagtgaagg agaaatcatc ggaatgggat ggctagatcg gctagattta attgcctgga
     2341 tccaactcat cttagatgaa cagccgaatg cgtccattat tttacacggc ggatcaatgg
     2401 gagcttctac gatcatgatg gcaagtggtg aaaaacttcc atcagcggtc aaaggattta
     2461 ttttagacag cggatatgtt tctgtttatg cagaattccg atatatgtta agtaaaatca
     2521 ctgtctttcc taaaaaaatg gtcatgagat atgcgaatca ttatgcccag aaatacgccg
     2581 gttactcctt aaagcaagca tcagctacga gacagcttgg cagcaatcat ctgcctttat
     2641 tagtcatcca tggtgaaaga gatcattttg tccctacaga agcagcgtac acgattcaaa
     2701 atgctacggc aggggataaa gcactgctgc ttgttccgga agcagaacac ttggaagcat
     2761 cgatgaaaga tccgaaaacc tattggacag tgattttttc atttattgaa caaagaataa
     2821 cgatgaatta attttctctt cttttttgta agtaattcga ggataaataa ttgtttatag
     2881 atcaggagac tgctaaaata aggtaggaat aaaaaaatat cagttatttg aggagtgcgg
     2941 catatggaaa tcaaagaaga aaaaatcgtc ttgctttatt caatgatgaa caacaagaga
     3001 tcggagaaat gacatggtca gatgcgggcc cagacatcat gatcgttgac catacatttg
     3061 tagatccagc atatcgtggt caaaagttag ctgaaaagct agtgtatact ggagtagaat
     3121 tagcaagacg agacgggaaa aagatcattc ctttatgccc ttatgcaaaa aaagagtttg
     3181 aaaagaaacc agaatatcaa gacgtcttac gtcagtcata agaataacag ctgaaagttt
     3241 tgaactttca gctgttattc catttatata gagttgtcac ggacttttat ctatgataaa
     3301 gttaaagaga cgatatcttt tgggaaggag gctgcgatat gtataattta attttgggaa
     3361 tcgtgatcgt tttatcgatt gttatggtca ttgcgattat gatgcagcca agcaagcaaa
     3421 atagtgcagc gagtgcattt accggcggtg cggatcaact attcggcaaa caaaaagctc
     3481 gcggctttga agctgtcatg cagcgatcaa ctgcagttat gggagctatc tggatgatct
     3541 tattatttgt cctagcatat ttatcttcga agtagttgaa taagcctctc gcaaaacggc
     3601 gggcggcttt ttttattgca aagagaacgc ttaagaagaa gttatgaaag aaactatggt
     3661 aaaatgaggc gaaagaggtg agacgagtga gacaattacc aaaacccctt tatgcaaaac
     3721 atggaaagcg agcggttttg ctgcttcacg cttactcagg aagtccaaac gatgttcgaa
     3781 tgctcgcacg atttttggaa aaagcagatt atacagttta tgcgccgctt tttaaaggac
     3841 acggaacaat ggagccatat gatatcttgc aagaaaaagc agaaagctgg tgggcagaca
     3901 ctaaaaaagc catccatttt ttacagtctg agcagttttc tgatattgcc gtattaggat
     3961 tatcaatggg cggcatcttt gctgtacgag cactagaaga agaatcagtg attggcggcg
     4021 gttttttctg ttcgcctttg tctcctgtaa aaacaaacgt gcctgaaaac tttgaaaaat
     4081 acgtacgtca agtgctgaag acagcaggta aatcagagaa agaaatcaat gaaaaagcag
     4141 ttgcttaccg ctcgttagct gaacaacaat taatggatat acaagatcag gcagcaatcg
     4201 tagaaagtag gttgtcagat atccaacagc cgatattttt agctcaagct gggaaagatg
     4261 aaatgatcga ccctaatggc gtatttgaaa ctgcacgcaa gttgagccgt cagcgagtga
     4321 cacttcaatg gtatcctgaa agtggtcatg tgattacagt tggtacagca agacgcgaat
     4381 tagaaaaaga cgtcttggaa tttttagaaa aattaccttg gaatgaggaa taaatatgac
     4441 aaaagaaacg ataaaagaga aaattctctt tttcatggaa agcagtcgca aacgcagttt
     4501 ttctatggaa gaaatcgctg aaggtttagg gttccaaaaa agcgatgatt ttaaattact
     4561 agtacaaacg attgctcaaa tggaaagaga acagagtata gttttcaata aaaaaggaaa
     4621 agtgaaactt cctttaaaac caatcctgat cgaaggaaca tttcgagcaa atgaacgagg
     4681 atttggattt gtaacgattg atcccgaaga agatgacatc tatatcccaa aagaagcgac
     4741 tggttttgca atggatggag acaccgtagc aatcgatatc atgaagcgag caaatacaga
     4801 tatggatcgc ggagcagagg ggaaagtagt cgagattcga gaccgggcga ctactcagtt
     4861 agcaggggaa ttcgttgctt attcagaaga agaaatacaa gaaacagatc tttacggcgt
     4921 tgttatcccg aaagatagaa agctcaacca atttaaagta tatgcagcag cagagggagt
     4981 tcgtccagtt gacggaagta ttgtgctgat cgaactgacc cattaccctg aaaaagggta
     5041 tgcgactagt ttagaaggga taatcaagca agtgattggt cataagaatg accctggcat
     5101 ggatatcctc tcaattgtcg tggctaatgg tatccctacg aaatttcctg atgatgtatt
     5161 gtctgaagca gatgaagttc cagatcaaat cagcgaaaag gatataactg gacgtagaga
     5221 tttaagaaat cagctcattg ttacgattga tggagaagat gcaaaagatc tagatgatgc
     5281 agttacggtt aaaaaattag ataacggtaa ttattttctt ggagtacaca ttgcagatgt
     5341 ttcttactat gtgacacaag gcagtcaatt ggacagagaa gcatatgaaa gagggacaag
     5401 tgtatatttg actgatcgag taattccgat gatcccgcaa cgtttatcga atggtatctg
     5461 ttcactgaat ccccatgttc caaggctgac catgagttgc gaaatggaga ttgatccaaa
     5521 tggacaagta gtctctcatg atattttccc aagtgtgatc caaacaacag aacggatgac
     5581 ctacacagct gtcaatcaaa tcttagaaga tcaagacgaa gaaacgatgc aacgctatgc
     5641 tcagctcgta cctatgttcc aagaaatggg tgaattgcac cgaatccttg aaacgatgcg
     5701 aatcaaacgt ggcgcgattt cttttgagga tcgcgaagcg aaaatccttg ttgatgctga
     5761 aggacaccca aatgacatcc agctaagaag cagaggaatt ggtgaacgct tgatcgaatc
     5821 tttcatgctt gcggccaatg aaacggtagc tgaacattat aataaattaa atctgccgtt
     5881 tatttaccga atccatgaac agccaaaaga agaaaaaatg cagcgcttct ttgattttgc
     5941 ttcagctttg ggcattctgg tccgaggaac gaaaggaacg atcacaccaa aagatttaca
     6001 gcatgtgatc gaaggagtag aagacaaacc agaagctgca gttatcaata ctatgttgct
     6061 aagaagcatg caacaagcac gctattcaga agacaatttt gggcattatg gcttagcggc
     6121 agattactac acacacttta catctcctat tcgacgctat cccgatctaa tcgtccatcg
     6181 tctgatccgt tcttacagtg aagataaaag tgaaagcaat caaagttcgt gggctgcgga
     6241 acttcctgaa attgcagatc atagttctaa gatggaacgt cgtgcagtag aaacagaacg
     6301 tgaagtagat tccatgaaga aagcagaatt catgatggac aaagtgggag aagaattcga
     6361 tgggatcatc agctctgttg tgaaattcgg cctgtttatc gaactgccga atacagtaga
     6421 gggattgatc catatcaatg aattgaaaca ggactacttc cattttgttg aaaatcattt
     6481 agctcttgta ggtgaaagaa ctggtctgac ttttaaaatc ggacagaaag tgcgagtaaa
     6541 agtagtcaaa gctgatccag atgaacgagc agtagatttt gaacttgttt ccgcagaaga
     6601 ggttacagcg ttggaacggc caaaaacacg aaatggaaaa tcaggaaaac gcgaaggaaa
     6661 acaagcagga aaacgcccag aaagaaatgg caagaagaac aaacgatata gcgatagtaa
     6721 gcaaacgttc ggtaagaaaa aagggaagaa gccattttac aaaggtgtta aaaagaagaa
     6781 aaagaaaaaa taaaatgagt tggaggaaac agctatgcca aaaggcgagg gaaaattaat
     6841 tgcacaaaac aagaaagctc gccatgatta ttcgatcatc gacacgatgg aagcagggat
     6901 ggtcttgcaa ggaaccgaga tcaagtcgat acgaaacagc cggatcaatc taaaagatgg
     6961 atttattcgc gtccgcaacg gagaagcttt cttgcataat gttcatatca gtccttatga
     7021 acaaggaaat atttttaatc atgatccgtt gcgcacgaga aagttattat tacacaaaaa
     7081 acaaatcatc cggcttgaaa atgaattgaa aaatactgga atcactgttg ttcctttaaa
     7141 agtctatatt cgtaacggct atgccaaggt attgattggt ctggcgaaag ggaaaaaatc
     7201 ttatgataaa cgggaagatt tgaaacgaaa agatatcgat cgacaaattg atcgaacatt
     7261 aaaaaatttc tctagataat ttcattatcc tttttcgcat attcggtgct tttgctttta
     7321 cttaatgata aaatttgtta gcatttaatc tgataaaaca tgattatcat aggttttttc
     7381 ttagatcagg agcaccgtgt ataaagaaaa attcgcttcg tttttgactg aaataaaaaa
     7441 gtgtctaatt ttcatgaaaa tgttttgaat tttctgtttc atggtggtat gataccgtgt
     7501 ggttagaaac cgattggaaa aaaccagata cgcacatgaa ttgattttat gtgaatttcg
     7561 gggaaaagag gtgaaatgga ttggatgaac gctcgctaac gttccacatt ggaccaattt
     7621 ggtttgatgg tacagtttgt ataatggtgt tactgacctg tttgattgtt ttcttcttag
     7681 cttacttttt tacaagaaat cttaagttga aaccaacagg caaacaaaat gcgatagaat
     7741 gggtcattga ttttagtcga ggaatcgtaa cagataatct gcctagaaaa gaattgagca
     7801 atttccattt gttggcattt acattgtttt tatttgtttt tgttgcaaac aacatcggtt
     7861 tagtaacaaa aatcgtttta cctaacgaaa caacactttg gaaaagcccg acagcagacc
     7921 cgtttgttac tttaactttg gcatttataa tgatcttact tactcactta ttcggggtga
     7981 aaaagttagg cttcaaagga tatttcgtaa attcgttctt gaaaccctat agttttatgt
     8041 ttccgatgaa actgattgaa gaatttacaa acttattaac acttgcttta cgtctttatg
     8101 ggaatattta tgcgggggaa gttttgctaa ccttgattgc aaaaatgatg acaagcttag
     8161 gctggttctc attaccatta gcaattccat tagagatggt ctggatcgcg ttctccttgt
     8221 ttattgggag catccaagca tttgtctttg tcactttgtc aatggtttat atgagccata
     8281 agattgaagt agaagaataa tactcggtta aaaaacaaac tactatttat ctattttagg
     8341 aggaaaacaa ttatgaatta tatcgcagca gcaatcgcaa tcatgggagc agcaatcgga
     8401 gccggttatg gtaacggtca agttatctct aaaacaatcg aatcaatggc tcgccaacct
     8461 gaaatgtctg gtcaattccg tacaacaatg tttatcgggg tagctctagt tgaagctgtt
     8521 cctatcttag gggtagttat cgccttgatt ctagtttttg ccgtttaatt gaatcagtat
     8581 taaggcagaa acaacatcgt ttgttactgc ttttttacat ggaaactaga aatactccaa
     8641 agaaaggaag gctcgcctat gctgaatcaa ttggcaattg cagaagttgg caatgcgatg
     8701 ttaggtaata tcatcgttgt cagcggctca tttttgatac tactggctct cttgaagcac
     8761 tttgcttggg gaccaatcag cgatattttg aaaaaacgtg aagacaagat cgccaatgat
     8821 ttagattctg cagaacaatc tcgcatcaac tcagcgaaaa tggaacaaga acgcgaacaa
     8881 caattgttag cctctcgttc tgatgcagct gatatcatca aaaatgcgaa agaaagtgga
     8941 gaattaagcc gccaaaatat tttgaaggat gctcaagaag aagcagctcg tctaaaaagc
     9001 aaagcccaag ctgatatcac tgtagaacgt gattcagcgc tgaactctgt aaaagacgac
     9061 gttgcagaac tctctcttca aatcgcggaa aaaatcttga acaaagaatt atctccagaa
     9121 atgcatgaat cattaatcaa tcaatacatt gaaggtctag gttcttcaaa tgaaactaga
     9181 taaatataca gtaggaagac gttacgggaa agctttattt gaactggcga tcgattcaaa
     9241 tcaagcagaa gaaatctatc aagatctcgt aagtttacgt caaatctatg aacaagtacc
     9301 tggattaggg aatatgttaa gtgatgttcg tctagaacct catgaaaaac gagaaatcat
     9361 ggacaagctt gtcagcggtt atgatgggat cgttaaaaac tttttagaag ttgtttatga
     9421 gtataaccga atggatgacc ttttgttcat gatcgaagaa tatgaacgtc gatatgatga
     9481 acatcaaggg ttactattgg gaagtgtcac aacagcagtc ccactttcag acgaacaacg
     9541 aatacaatta gaaaagaatg ttgcaaaaac aatggactat caatcagttg aattaaaaca
     9601 aatcgttgat tcttctatta ttggtggcgc gattgttgaa gccaaccatc gagtaatcga
     9661 cggaagcatt cgcacgcaat tagaaaaaat gcgtaatcaa ttaaacagat agtacaaaga
     9721 ggtaggtgaa tcgaatggcc atcaaagcag aagaaattag tgccttgatt aaagaacaaa
     9781 ttgaaaatta tcaaaacgtg ctttcagtcg aagaaatcgg taccgtaact tatgtaggtg
     9841 acgggatcgc tcgtgcacat ggtttagaaa acgcgatgag tggtgagttg cttgaatttt
     9901 caaacggctc atacggaatg gcgcaaaact tagagtcaaa tgatgtaggt atcattatcc
     9961 ttggcgattt cgagtccatt cgtgaaggag ataaagtaaa acgaacaggt aagatcatgg
    10021 aagttccagt tggagaggcc ttgatcggtc gggtagtcaa tccgctaggt caaccaatcg
    10081 acggactagg tgaaatcgtt actgacaaag ctcgtccagt agaagcgatg gcaccaggtg
    10141 ttatgcaacg taaatctgtt aacgaaccaa tgcaaacagg gctaaaagcg atcgacgccc
    10201 ttgtgccaat cggacgcgga caacgtgaat tagtcatcgg tgaccgtaaa acagggaaaa
    10261 cttctattgc gatcgatacg atcatcaacc aaaaaggtca agatatgatc tgtatctatg
    10321 tagcaatcgg acaaaaagat tctacagttc gtacacaagt tgaaacattg aaaaaatatg
    10381 gcgcaatgga ttacacaatc gttgtgaatg ccggtgcgtc tcaaccagca ccattgcttt
    10441 atatcgcacc atatgctggt actgcaatgg gtgaagaatt catgtacaac ggtaaacatg
    10501 tattgatcat ttttgatgat ctttcaaaac aagctgttgc ttatcgtgaa ctttccttgc
    10561 tacttcgccg tccaccaggt cgtgaagctt atcctgggga tgttttctac ttgcactcac
    10621 gtttattaga acgtgcagca aaattaagtg atgatttagg tggcggttca atgactgcct
    10681 taccatttgt tgaaacacaa gctggagata tctctgctta tatcccaaca aacgttattt
    10741 cgatcactga tggacaaatc ttcttagaaa gcgacttgtt ctacgcaggt actcgtccag
    10801 cggttgatgc cggactatct gtatctcgtg taggaggttc tgcgcaaatc aaagcaatga
    10861 aaaaagttgc tgggacttta cgcctagact tagcaagtta ccgtgaatta gaagcattta
    10921 cacaattcgg ttctgacttg gatgcagcaa cacaagcaaa actaaatcgt ggacgccgta
    10981 cagtagaaat cttgaaacaa aaattgcatg caccgctagc tgttgaaaaa caagtagtga
    11041 ttttgtatgc tttgacacat ggattcttag atagtatccc tgtagacagt attttagact
    11101 tcgaacatga attattcgaa tatctggata ccaatcattc agatatcttt gaaacaatcc
    11161 gtacaacaaa agatcttcca gaagaagaag cgttgaacag tgcgattcag gaatataaag
    11221 acatgttctt agctacaaaa ggaagtaatt cctctacaga agataaattg aaatccattc
    11281 aaaatgcata gtgaggtgag atgaatgggt gcttcattaa atgaaatcaa gacacgtatc
    11341 gcttcaacga aaaaaacgag ccaaatcacg cgggcaatgc agatggtgtc tgcttctaag
    11401 ttgacaaaat ctgaagcttc ttcacagaag tttcaggttt atgcaacaaa agtaagagaa
    11461 atcgttacgc atttgactgc tactcagtta aatgatattg cctcagaaaa tcctagaggg
    11521 gatatcaatt acaacagcat gctgctcagc cgtcctgtga agaaaactgg ttatatcgtc
    11581 atcactgcag atggcggttt agtcggtgga tataacagct cgatattgaa acaaacgatg
    11641 tctattttag aagaagacca ccaatcaccc gatgattacg tgatgatcgc aattggcgga
    11701 actggtgcag acttctttaa agcacgcggt atcaatctag catatgagct gcgcaatcta
    11761 tctgatcagc caagctttga tgaagtccgc aaaattgtaa atatggcaac aactatgttc
    11821 caaaacgaag tattcgatga attatacgta tgttataacc atcatatcaa ttcgctaact
    11881 agtcagtttc gtgtagaaaa aatgctgcca atctcagact tagatccaga agaagcaacg
    11941 actttcgaac aagaatatat ttttgaacct tcaaaagaag aaatcttgtc tcagttattg
    12001 cctcagtatg ctgaaagttt gatctacggt gcgatcgttg acgccaaaac agcagaacat
    12061 gctgctggta tgacagcaat gaaaacagca actgataatg ctgctaatat cattgatgag
    12121 ctgacggttt cttataaccg tgcaagacaa ggggctatta cccaagaaat taccgaaatt
    12181 gttgccggag cttcggcact agaatagtat tgagattgga ggaaaaaaga tgagttcagg
    12241 caagattgtt caagtaatcg gtcccgttgt cgacgtggaa ttttctttag accaatcctt
    12301 accagatatc aacaacgcat tagttgttta taaaaatgac gaaaataaat caaaagttgt
    12361 tcttgaagca gcgttagaat taggggacgg agtgatccgg accattgcga tggaatcaac
    12421 agatggttta caaagaggaa tggaagtcat tgatacaggc aaagcaatct ctgttcctgt
    12481 aggtaaagaa acattaggtc gcgtattcaa cgtactagga gatacgatcg atttagaaac
    12541 acctttccca gaagatgcgg aaagaagcga aattcataaa aaagcaccag cctttgacga
    12601 attaagtaca agtacagaaa ttttggaaac agggatcaaa gttatcgatt tgcttgcccc
    12661 atatttaaaa ggtgggaaag tcggactatt cggtggtgcc ggtgttggta aaaccgtact
    12721 gatccaagaa ctgatccata atatcgccca agaacatggt ggtatttctg tatttaccgg
    12781 tgtaggtgaa cgtactcgtg aaggtaatga cttgtattat gaaatgaaag attcaggagt
    12841 tatcgaaaaa acagccatgg tgttcggaca aatgaacgaa ccaccaggtg cacgtatgcg
    12901 tgttgctttg actggtttga cgattgcgga atatttccgt gatgtagaag gtcaagatgt
    12961 actgttgttt atcgacaaca ttttccgttt cactcaagct ggatctgaag tatcagcctt
    13021 gttaggacgg atgccttctg cggttggtta tcaaccaaca ttggcaacag aaatgggtca
    13081 attgcaagaa cgtatcacat ctacgaaaaa aggttcgatc acatcgatcc aagcaatcta
    13141 tgtgccagcc gatgactaca ctgacccggc gccggcaaca gcattcgccc atttggatgc
    13201 gacaaccaac ttggaacgta aattaacaga acaagggatt tatccagcgg tagatccatt
    13261 ggcttcttct tcaagtgctt tagcacctga aatcgtggga gaagaacatt ataaagtagc
    13321 aacagaagtc caacacgtat tgcaacgata tcgtgaatta caagatatca ttgctatctt
    13381 aggtatggat gaattatccg atcaagaaaa agtgttagtt tctcgtgccc gcagagtcca
    13441 attcttcttg tcacaaaact ttaacgtggc tgaacaattt actggtcttc caggttcata
    13501 tgtccctgta gaagaaacag tgaaaggatt ccgcgaaatc ttggaaggca aatacgatga
    13561 tcttcctgaa gaagctttcc gaagtgttgg ccgaatcgaa gacgtcgtag aaaaagcgaa
    13621 aacactaggc tactagaaag gggtgcccca tggatcaata tttaacagta aatgtggtaa
    13681 ctcctgccgg tttggtctat gatcaccatg cagctatcgt cgttgcacgt acgacagctg
    13741 gtgagcttgg gattttgcct aaacatgcac caatcatcgt tccattgacg attgatgaag
    13801 ttcgtgtaaa acgaacagat tcagataccc acgtcgattg gatcgctgtt aatggcggaa
    13861 tcatggaagt tcgtgataat gttgtttcaa tcgttgctga tagtgcggaa cgtgaacgtg
    13921 atatcgatgt atctcgtgcg gaacgtgcaa aacaacgcgc agaacgccaa atcgaagaag
    13981 caaaagcaaa acaagatacg aacgaattga aacgggcaac tgttgcgttg caccgagcaa
    14041 tcaatcgtat caaagtatct aagcactcat aaaatgagat gcggatgttt atccgtgttt
    14101 aagaacagta aaaagaggtt atgacagaag tggtcagctt caagacataa gaaggaattt
    14161 acgaaaattg cttctcaaat ttttgtgaaa tctcagctta tttttcgaag aagctacttc
    14221 tggaacaccg tatatcagag gttgtgaaat cagcgttttg tcctgagtat tagagaaaca
    14281 aatggaaaat agttcctcat attttgccgt tttttgagct aataccgagg gtcagatgat
    14341 tgaacaccgt ttatttggaa taagggactg cgacaagact tttgtctcag tccctttttt
    14401 tgcatatttt tagcatttat ttcctaaaaa atgtaagggg attcctatat ttttaagtat
    14461 acttgttttt ccttttatac attttatggt attatcattt tattagttat tataaaacaa
    14521 tcgttagaaa ggacgtcatt atgcaagtat acggaattga tgcggtgctt cgaatcgtga
    14581 gtcatttggc gtttatctac ttagccttct ggtctttacg ttcgttacgc attgaaactt
    14641 ttttcagacc aatgcataat acgcaaatta gaatggcaat cgtacttttt tcaatttttt
    14701 tagggtacac tgcaagtaat tttttcttag aggttatcgc tttatgccga aatcttttcg
    14761 ttagcctgta aattttaaaa aaaggtacta ttttaaaagc aaggatgtta taatagaaaa
    14821 gattttgagt aagtgtatgc tcattggaat tttttggagg gaacaacatg gaagagatca
    14881 tcgtaagagg tggcaatcaa ttaaatggaa cagtaagaat tgaaggagct aaaaatgctg
    14941 ttttgcctat tttagctgct agtttgttag cagaagaagg tattacgaca ttagacaacg
    15001 ttccgattct ttctgatgtc ttcactatga atcaagtgat tcgtcactta aacgtagatg
    15061 tagattttga tgaacaaaag aatcaagtaa caatcgacgc ttcaagacaa ttagaaatcg
    15121 aagcgcctta tgagtatgtt agtcaaatgc gtgcttcaat cgttgtgatg ggtccgctac
    15181 ttgccagaaa tggacatgca aaagtagcta tgcctggtgg atgtgcgatt ggtaaacgac
    15241 caatcgattt gcatttaaaa ggatttcaag ctttaggagc aaaaattatt caaaaaaacg
    15301 gctatatcga agcaattgcg gatgaattga tcggtaacac gatttattta gatttcccta
    15361 gtgtaggtgc tactcaaaat atcatgatgg ctgccgtaaa agcaaaagga acaaccatca
    15421 ttgaaaacgt agctcgcgaa ccagaaatcg ttgatttagc aaacattttg aataaaatgg
    15481 gcgctcaagt ctatggagct ggtactgaaa caatgcgtat tgaaggcgtg gatcatttac
    15541 atgcagtcaa ccactcaatc gtacaagatc gtatcgaagc aggtaccttt atggttgctg
    15601 ctgcaatgac acaaggcaat gtgctgattg cagatgctat ctctgaacat aaccgcccat
    15661 tgatttctaa attgatcgaa atgggtgcag aaatcattga agaagaaggc ggagtccgtg
    15721 tcatcggacc aaaacatatc ttacctacag atgtaaaaac gatgcctcat cctggtttcc
    15781 ctacagatat gcaagctcaa atgacagcta tccaattagt tgcagaaggt acaagtgtgg
    15841 tgactgaaac agtgtttgaa aatcgtttcc aacatttaga agagatgcgc cgtatgaacg
    15901 ctcatgtcaa aatcgacgga aatgtagcaa tcatggatgg aaaccatgaa ttgcaaggtg
    15961 cagaagtata tgcaacagac ttgcgggcag cagcagcatt agttttagct ggcttgaaag
    16021 caaatggaat cacacgtgtg cgtaacttga attatctaga ccgtggatat tataatttcc
    16081 atatcaaact acagcaatta ggtgcagacg tcgaacgtgt agacatggat caaacttctg
    16141 ctgaaaaaac agcacaaacg attgcttaag gaagtggctg aatgagtaac caacgatata
    16201 tcttattaac tttgataaag attttagtgg tgatcttatt gcttatcctt ctttttgtgg
    16261 ccggaacgat gatcggatat ggtgtcatcg gtggcggcaa tccatttaaa gtattccagc
    16321 caagtttgtg gattcatatt cgagactttt ttcattgata aataagaatc acagtggttc
    16381 tagtcgatat gaagtgagcc atgaagcaga acatgataaa agaaaacaga agggaacgtt
    16441 gacgttagtc gcgatccctt tttttagtaa aagaaaagaa ggaatctaat tgatgaagaa
    16501 gatattgatt tatttagtta gaggatatca gcgctttatt tcgcctgcat ttccacctag
    16561 ctgccgttat tacccaacct gttccaatta tatgataaaa gcaattcaaa cccatggtgc
    16621 gctaaaaggg acggtaatgg ggactgcacg gatcttacgc tgtcatcctt ttgtcaaagg
    16681 cggtatcgat tatgtaccat tgacattccg attaacgcga aataagaaag ataaaaaaga
    16741 accagattat aaaaaggttg tgaaaaatac gggtagcact gagcgataaa gaaaaagagg
    16801 aaatttattg tcaaagtaac aactccgcaa ctacttatat gggggacaaa aaatgatcga
    16861 agaactaaac aagaaagatt taccatggtc cttgttatta gatgcagatc ctgataaaga
    16921 aaaagttcaa gtatatgttt ccagagggag tggctggata tggaaagaaa aagaaaaaac
    16981 aataggtgta ctgatctatg tggcaaggga aaaagaatac gaaatcgtca atgtagcagt
    17041 aaccccaacg tatcaaggaa aggggattgg cggaaaatta cttgagacag cttttcagaa
    17101 gctttcacag ctagcttcaa accaaactcg gatcattata cgtactggca ctactagtag
    17161 cgctgcgtta cacctctatc aaaaaatggg ctatgtggag attggtcgag tcaaagacta
    17221 ttttatccat cattactctg agcccatttt tgaaaatgga gatcaattaa gggatcaagt
    17281 gattttagca attcacttac ctaaaaatag ctttaactaa taaactttca attcgagaaa
    17341 atgctttcaa atgctaaata gatacattac aatagcttta gcaaacaaaa aggagaatat
    17401 ttttatggga atattagttt ttgattttgg tggatcggct gtcaaatatg gttgttggga
    17461 tggcaaagag attaaaggta agggacaatt tgcaacgcct gaatcttggg aagaaatgaa
    17521 aacgcaatta tttcaagttt ataaaaaaat actcgtttct tttgaagtcg aaggaattgg
    17581 aatcagctct cctggagtag tgaataatga gaaacaggtg attgagggaa tcagtgcgat
    17641 tccttatatt catggattta atattttccg agatttggaa actctgtttc aactcccagt
    17701 aacgattgaa aatgacgcca actgtgccgg aatggctgaa ttttatgaag gtgctgcccg
    17761 tgattatcaa gatgttgctt ttgttgtggc aggaactggg attggcgggg cgttgttcac
    17821 gaaaggacaa ataaataaag gggcacatct ttacggtgga gaatttgggt tgatgttctt
    17881 agatggcgat aagacattca gtaaacttgg tacagcggta cagatggctt ggcgttattg
    17941 tgaacgcaaa ggtctcgata aaaatgctta taccggaaaa gatgtctttg aattagcaga
    18001 aactggagat gcaatagcaa aagaagaagt tgagagtttt tatacgtatc ttacaaaggg
    18061 attattcagt attcaatttt cgtttgatcc agaagtgatc gtattaggcg gcggggtttc
    18121 tgcaaaagaa gggctcattg atgagatcaa aagccgaatg aagaagctga cagaacaatt
    18181 cgatctgcat gatttcgaac cgcagatttt attatgtgag tacagaaacg atgctaatct
    18241 tataggtgca gcagcaaact atctcgctgt acgtcaagga gagaattaag agctttagag
    18301 aaggtgcagc ttgcataaaa gaagagaatg aaatgaatag gagattttta cctaaggaat
    18361 gttttatttg ctgcagtatg ataaaatatc tgagaggtga aaatgatgtc aaaaaaaaat
    18421 aaagatattg aagtgcgtat agaagaagtg aaaaaagata tcaaaggtaa gaattatgaa
    18481 gtcactcagt tatttatagg gaaaaaaatg attggtgaga tcttagccta tgggccaaaa
    18541 gaatatgaaa ttttctttgg tgaagaagat tttggaaaag aaaaaagtct tgaaaatgcg
    18601 atagaaacag tgattcgaca ctggaatctg cacgaataaa aaaatatcaa aaaaactttc
    18661 aataaagggt tgcaaaaatc tggaaaatta ggtattataa ctaagtcagg ttgatacaaa
    18721 cctttcggag gagtagcgaa gtggctaaac gcgacggact gtaaatccgt tccttagggt
    18781 tcagtggttc gaatccactc tcctccattt cattggggta tagccaagcg gtaaggcaag
    18841 ggactttgac tccctcatgc gttggttcga atccagctac cccagtatac cacaatcgta
    18901 agctctcgtt agttcgagag ctcttttttt ttgctttgct accttgttcc ttgaagattc
    18961 tgctgaatta agatagagtt aagttaacta caagaattgg agggatccac atgaaatgga
    19021 aagaaaaagt agacgaagca gctgaaaagt tatatgattt ggtcaaatca gaaaaataca
    19081 atattgaagt gaatattccg aaaaaaggcg gaaaagcggt ccaggtaaaa tcaaaacgcc
    19141 caacgaatca tacaaaaaaa tggatggcta aaaaccgcta ataataacaa aagatccata
    19201 agtcggcatt ttcatcgatt ttagggtctt ttgttatttt ctaggttgaa catatctaaa
    19261 aaattgtttc tgacaatagg agtagggaga acgatgtgtg tctaaatcct ctgttgatgg
    19321 atagaaacct ttatcttttt cagttgtgaa tcaggtatat accagttata atagaagaaa
    19381 cgaaaggacg ggtgtacgtt atgtcgaatc aattacctgt atatatacag attcatgacc
    19441 aattaaaaaa tgaaatcgaa caaggtatat ggaaagtcgg agaccgtctt ccttcagaaa
    19501 gagaattagc agtgaaattc aatgtcagcc gtatgacgtt gagacaagca attcaaaact
    19561 tggcagatga aggaatctta gaaagaaaga tcggttcggg tacgtatgtt gcgcgagaaa
    19621 aagtacaaga aaaaatgtct ggtgcaacaa gttttacaga aattatggaa tcacaaaatc
    19681 gagtaccgtc tagtcggaca atctcttatt tcttgacttc gccaagctca agtgaaatgg
    19741 aaaaactaaa cttgagtaaa gatgacacga tcttgcgaat ggaacgtatt cgtttcgcag
    19801 atgatgtccc tatttgtttt gaagttgcca gtgttccaca aaagctgatc gatggctaca
    19861 gcaaagcaga gattactgaa tcgttgtatc gcacgctaga agaaaaaggc gggaaaaaga
    19921 tcggtccagc gaatcaaacg attactgctg tgttggcttc tgagaaaatt gctgactatt
    19981 tagaggtaaa acgaagagat gcagttcttc gtttgcgcca gatttcttat tttgaagacg
    20041 gtacgccgtt tgagtatgtg cgtacgcaat acgtaggaaa tcgttttgag ttttatttgg
    20101 aaaaataaaa aacaggtgat ccctgattcc ttattagaaa taaaagagaa tcagaatcac
    20161 ctgtttttat atatgatcag ttatcagttg ctcgtgataa gaaacagaac cctcttcaaa
    20221 ttggacttgt ccgttcagca gctcaatgat ggattcttta aagtggttag cacttttttc
    20281 atctacagca cagatgacgc taacttgatc agtatattgg atttctttta taaaaaaatg
    20341 ttggagttca agataattct gtaattttcc tagttgcgga tacgtgatca tcacagagat
    20401 ctcctgttgc aaggtacctt ctacgattcc aatgtcagac aatgcttgag agaccgcatg
    20461 agtgtatgct cgtattaatc cgcctgtgcc gagtttcgtt cctccaaaat atcgagtgac
    20521 tactgcagct acattgatca gttgattttt tttgaggact tccaacatcg gtacgcccgc
    20581 cgttccactt ggttctccat catcgctgct tcgctggatt tcattttttt ctccaatgat
    20641 gaaggcgctg cagttatggt tcgctttcca atgttctttt tttatttctt gaatgaaatt
    20701 ttttgcttgg tcctctgatt ctattcgtct aagagaacag ataaagcgtg attttttgat
    20761 ctcaatctca ctttgtccat tttcttttat tgtacgatag cgctcgatca tcttgtcacc
    20821 tctttttttc attttcttta ttcagtataa ataaagttct aggttgtttc aacactgtaa
    20881 cggttgcgca attgctgtag tatgcgataa taaagacaaa ggcaggtgga tctggggatg
    20941 caggaacgaa tgaaaaagta cgatgcaatt acgcattatt tgaagaacaa tggcggctct
    21001 caagtaacgt tgacctttac ccaatttgac gaactgctgt ttcccagtaa cggacttccc
    21061 aaaacagcaa gggaaagtac agattggtgg gcaaatgatt ataaacaccc tgaaaaaggt
    21121 gcctatggct ggataaatgc aggctatgaa gtagttgtca tcaatttgga caaagaatat
    21181 gtcgtgttca ataaattagt gaaatctagt tggctatttg attaaataaa ccgcgtttag
    21241 aaaacgttga caaatttctt tctttttata taataaagta acagacgcga agaaaacgtt
    21301 tgcgtagttt gttttaaaaa ggagagaaaa atatggctaa aaaaacaatc atgcttgtat
    21361 gttcggctgg tatgagcaca agtttactag taacaaaaat gcaaaaagct gctgaagcaa
    21421 aaggaatcga ctctgatatt ttcgctgtgt ccgcttctga cgcagataac aatcttgcaa
    21481 ataaagacgt ggatgtgttg ttattaggcc cacaagttcg ctttatgaaa gctgattttg
    21541 agaaacgtct ggaaccaaaa ggcattcctt tagatgtcat caatatggct gattatggta
    21601 tgatgaatgg cgaaaaagtg ttagatcaag caatcgcgct cataggtgaa taaatagaac
    21661 agtataacta tcgaacaagc gatccaaaaa atagatcgct tgttttttcg tatatttttt
    21721 tagggcgaat aatatgaatc atttttgggg tagaaggctt ctgacgagag atattaaagc
    21781 aatagactgt gaggaggtaa atttaccaaa ttatgagaag atcgcagcag tggaacgttt
    21841 gggcaactgg attctttgtc atcgctgtgg aatgaggacg tccgtcattg ttggacagct
    21901 tgcagattac ggttattttt gtacacattg tctatattta gggtgatgcg acactcaaca
    21961 agatttatat ttgtttgatc agcctgaagc aaaacctcga gaagtcgtct ttttttggac
    22021 aggacagctt actgaaaaac aaacggaaat cgcaaagaga atactttgcc attcagaaaa
    22081 aagacatcat cttatttggg ctgtaacagg tgcagggaaa acagagatgc tttatcctat
    22141 tttagtggaa actttaaaag ctggaggaag agtagcgatt tgtacaccgc gagtcgatgt
    22201 ttgtaatgaa ttgtttttac gctatcgtta tgtttttcca gaagaaaaaa tcacgttgct
    22261 ccatgggaat acagcaacgg cttatacctt tacttctttt gttatctgta cgattcatca
    22321 gctataccgt ttttatcggt cctttgattt aatagtgatc gatgagatcg atgcgtttcc
    22381 ttataacggg gatgctgggc tagctcacgc tgtgcaaaca gcaatcagat caaacggccg
    22441 attcatctac ttaagtgcca cgcctgatga gaagttacta aaggaaatca agcagacatt
    22501 tgagctccac aaacttgcct tgcgctttca tcggcgcttg cttcctgaac ccgtgcttgt
    22561 tttcatgaat aattggcgac aaaaatgtgg aaacaaaaag aaaatcaact ctttggtgcg
    22621 gatcattcag caactaatca aagaaaaccg tatcctttta ttttgtccaa gtattacgat
    22681 gatgcatcgt ttaaaaatca cactgcaaga agcttttcca gaatatgaga taacagatgt
    22741 ttcttcacaa gacgatcaac gggcaaagaa agttcagaaa atgcgagaag caatatacga
    22801 gatactgtta accacaatga tcctagaaag aggagtcaca tttgaaagaa tctctgtcat
    22861 cgttttagga gcagatcatc cagtttttac taaatcctct ttggtgcaaa tcgcaggaag
    22921 agctgatcgt aaaggtcctt atacgaacag tcgagtctat tttttctatg aagaaaaaac
    22981 ttcagctatt cgaaaagcct gtcaggaaat caaagaaatg aacgaagaag ggaagcagat
    23041 gctgtgagat gtagttgctg cggtaaagac atcattcaaa atttaacatt cagcgagatc
    23101 atcggagtgt cgaaatctag acttcctcag acatgttcag tttgccgcgc acaattccat
    23161 ttattagaag caaaaggttg tgcaggttgt caaaaaccaa tccatttgaa atacgaggag
    23221 acgaaaaaga aagcaaatac tagtttcgtt tactgcaacg actgtcaaga atggaagaag
    23281 aaatatcctg catatgattt tcaacaccgc gcctttttta cgtacgatga aaagatgcag
    23341 gcttggatca atcggtacaa gtttatggga gatatccgat tagcagggac ttttgcatat
    23401 aaatggactc agataaaaaa aagattaccc ggcatatatt tattgtccaa tacctttatc
    23461 tgaaaaaagg tggctagaaa gaggattcaa tcaagtaagc gagatgttga aagcagcaaa
    23521 aattcctttt cagatgctgc tcaaaagaga gcaacatctg cttgctcaag caaaaaacac
    23581 gcgaaaggaa agattggaga tgcctcagcc ttttgagctt gccgtacctc tttctaagat
    23641 acaacataa
//
LOCUS       DADGKS010000042        22634 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.042, whole genome shotgun sequence.
ACCESSION   DADGKS010000042 DADGKS010000000
VERSION     DADGKS010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22634
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.042"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(228..1115)
                     /locus_tag="JXV47_001751"
     CDS             complement(228..1115)
                     /locus_tag="JXV47_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAX1487793.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(1112..1981)
                     /locus_tag="JXV47_001752"
     CDS             complement(1112..1981)
                     /locus_tag="JXV47_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1487794.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(2118..3404)
                     /locus_tag="JXV47_001753"
     CDS             complement(2118..3404)
                     /locus_tag="JXV47_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAX1487795.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            3677..4255
                     /locus_tag="JXV47_001754"
     CDS             3677..4255
                     /locus_tag="JXV47_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAX1487796.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            4255..5184
                     /locus_tag="JXV47_001755"
     CDS             4255..5184
                     /locus_tag="JXV47_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1487797.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            5181..6917
                     /locus_tag="JXV47_001756"
     CDS             5181..6917
                     /locus_tag="JXV47_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAX1487798.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(6980..7816)
                     /gene="pheA"
                     /locus_tag="JXV47_001757"
     CDS             complement(6980..7816)
                     /gene="pheA"
                     /locus_tag="JXV47_001757"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HAX1487799.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(7813..8322)
                     /locus_tag="JXV47_001758"
     CDS             complement(7813..8322)
                     /locus_tag="JXV47_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HAX1487800.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(8315..9610)
                     /gene="aroA"
                     /locus_tag="JXV47_001759"
     CDS             complement(8315..9610)
                     /gene="aroA"
                     /locus_tag="JXV47_001759"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HAX1487801.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(9623..10714)
                     /locus_tag="JXV47_001760"
     CDS             complement(9623..10714)
                     /locus_tag="JXV47_001760"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HAX1487802.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(10731..11897)
                     /gene="aroC"
                     /locus_tag="JXV47_001761"
     CDS             complement(10731..11897)
                     /gene="aroC"
                     /locus_tag="JXV47_001761"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HAX1487803.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(11899..12963)
                     /gene="aroB"
                     /locus_tag="JXV47_001762"
     CDS             complement(11899..12963)
                     /gene="aroB"
                     /locus_tag="JXV47_001762"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HAX1487804.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(12996..14018)
                     /gene="aroF"
                     /locus_tag="JXV47_001763"
     CDS             complement(12996..14018)
                     /gene="aroF"
                     /locus_tag="JXV47_001763"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HAX1487805.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(14677..15651)
                     /locus_tag="JXV47_001764"
     CDS             complement(14677..15651)
                     /locus_tag="JXV47_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HAX1487806.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(15632..17515)
                     /locus_tag="JXV47_001765"
     CDS             complement(15632..17515)
                     /locus_tag="JXV47_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HAX1487807.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(17533..19758)
                     /locus_tag="JXV47_001766"
     CDS             complement(17533..19758)
                     /locus_tag="JXV47_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAX1487808.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            19873..20907
                     /locus_tag="JXV47_001767"
     CDS             19873..20907
                     /locus_tag="JXV47_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAX1487809.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(20974..21987)
                     /locus_tag="JXV47_001768"
     CDS             complement(20974..21987)
                     /locus_tag="JXV47_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAX1487810.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(22065..22253)
                     /locus_tag="JXV47_001769"
     CDS             complement(22065..22253)
                     /locus_tag="JXV47_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HAX1487811.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
BASE COUNT         6446 a         4863 c         4096 g         7229 t
ORIGIN      
        1 tgacaatcag gacagtcatc ggcaatatag cagcaatcac ttctttaaaa ttttttagca
       61 tgtatcctcc tcctttactc tttaagttta ccttaaaatg aaagagtttt cgagcacaaa
      121 cttaaaacgt tatcatttaa tttttctcaa cataaaataa cacacgtccc aaaagtatct
      181 ttttacttgg aaaaatgact ttgaaggaac gcgcttattg tgttttttta ttttacagag
      241 ccgatcattc cttgaacgaa ttgcttttgc aaaacaaaaa atacgatggc agttggtaaa
      301 gtagcgatga ctaatccagc catgatcatt ccatagtctg gtgtatagga agcacccata
      361 gcagataaaa caagcggaac cgtccgttta tcaggagatt gcaaagctac taagggccat
      421 aaataattgt tccagctact catgaatgtg atgattgcag ccgcggcata ggtattttta
      481 gccgtcggca tatacactct aaaaaaaata cttagttctt ttagaccgtc taatcgagcg
      541 gcttctacta gatcttttgg aaaagattta acattttgtc gaaagaagaa gatcaaaaaa
      601 gcagtgctaa cagatggcag gatgacaacc aagaaactgt tgattcccaa aaccgttccg
      661 ttcaattgtg aaaacattcg atataaaggg atcatcaatg ccgcaaaagg aaccatcatc
      721 gatagcagta gaatattgaa aattaggtct tttcgtttac tttgataaat ctcaaatcca
      781 tatcctgcca ttgacgaaat cagcaatgca aacacagtgg tcaccaaagc gatcatcgct
      841 gaattccaaa gggaacgagt aaaattcagc tcattggaaa acaaattttg aaaattgatg
      901 atcaagttac tgccaatctt tatttttccc gatgtgatat ccacgggtgt attcgtcatt
      961 cccaaaacca tccagacaaa agggaaaatg gaaataaatg ataggatgct taatgctgta
     1021 tactttaata ctgacccaat tgtcgaacga agttctaatg cttgtttttt gacgttgggg
     1081 cgttcgattg tttctttttc taccatattt ttcatcgact ttctcctcct actttcgttt
     1141 ggattatcga caatatcaca ataaaggaaa caataacaaa ggaaactgct gccgcatatc
     1201 caaaattagg cgtgaattta taactcaaat tatagatgta ttgagatagg gtggtcgttg
     1261 catttgctgg tcccccgcca gtaatatttt gtacttcatc aaaaagctgc aatgtcccga
     1321 tcgtcgaagt aatggaagta aacaaaatga ttggttttaa atttgggatc gtcactttga
     1381 taaactgctg ccatttagaa gcaccgtcaa tagatgctgc ttcataaatc tccgaatcaa
     1441 tattttgcat gcctgaaagg aaaaaaatca tattgtatcc agtccaacgc caagtgatcg
     1501 aaagaatgat cagaactctc gcccaaattg gatgagtcaa ccagccaatc ggtgtgtcaa
     1561 tcataccaat gcccaacaac aagttgttta caaggccaga ttgagaaaat agacttttca
     1621 tgatcagaga ataactgacc atcgaagtga tacatggaag aaagatagcg gttcgaaaca
     1681 accctttata tttcaacttt ttatcattta aaaggttgga aataaaaagt gctagaaaca
     1741 acatgatcgg tacttgtaca agtaaataca ggaatgtatt aaaaaaagct tttttaaaag
     1801 ttgcatctgt caacatccgc tgataattac ctaacccgtt aaatgtcata ttgacagggg
     1861 gaccactttg aaaagacgtg atcaaagcca aaaccatcgg aataaaaacc atgattgata
     1921 tcaaaatgac tggcaagatt aaaaaagcat gcccgttttt gaataaatct ttctgcttca
     1981 ttcttttccc tccaattcta tcattgatta tctacatgaa aagacaagaa agacaatatc
     2041 tgtaaggcag acgtgatctt ttttgtcttt tcgtttgtct gatgaaaaag cgaagaaatt
     2101 cactttttta ccaccgatca attagccaat tgtgcttcta cttgtttttg tgtatctgct
     2161 agtaccttgt ctgtctcttc tccattgatg attcgatgaa gagcttcagc tacgactgct
     2221 tcaattgcat aggtctcatg tccgtaattc acttctggta tttcagatgt ccatgttgaa
     2281 aaatcgtcaa agatcttttg accactgtaa aattcagaag cttcttgata agcttcttgt
     2341 tcattcgcgc taagcatcgt agatactagt ccgatttctt tcgcaagagt gcccatcagt
     2401 tcttcattcg aagcaaacgt tgcttctagg aaatctttcg ctgaatcttc tccagctact
     2461 cctttgatca cataccagcc agcgccgcca aggttagaag cttgcgcttt ttgcagattt
     2521 tctggaagtg caggtattgg tgcaatcttc cattttccag attggttttc tgctccttgg
     2581 atcgttgaag aataccaagc gccagttggg ctagaagcta ctgctcctga ttgtatcgca
     2641 gttactccag cattccagtc agaggtttgt tcgactagat cttctttcaa aagagtggca
     2701 aacaattcaa gaccatactt taaagatgca ttgtcttgga tcgtgactgt ctccccatct
     2761 tcagatgtat accattctcc tgcctgttgc ataatcatcc ttactcgacc aaggtcagaa
     2821 ggattgactt cagcgatttt ctttcccgtc ttttctttga catctcgcgc tacttgaata
     2881 tactcgtccc acttcagatt ctccatatcc tcttctgtat aacctgcttc tgccatcaga
     2941 tccgtacgat agaagtttgc tgttacgccc gaatcgaaag gaacaccgta tattttatct
     3001 cctactttgt ttaccgcaaa tttatacggt gcaaaatgat cttcctttac aatagcagac
     3061 aaattagcga atgcatctgg ataagaagtc aaatagcctt gtatcctata atcttcaatc
     3121 aagacgatat tgggcaatcc ttctgtattc ccgctcgcta aagcggtgtt cagtttctga
     3181 acgatatcat cctgagacat cgtaacaact tctatctctg tttcttcgtt ctcataaact
     3241 ttttttgctt cattcactgc tttgatattg aatgtctcat cccacgccca gacagtgact
     3301 ttttcttctt tgtctgctgt actactagca cttccgcatc ctgttaagaa acctgatgct
     3361 gccgctaaac aaacgactcc agcaattaac tttctgatgt tcatttttat ccgctccttt
     3421 tccatccatt agttgtttac gtttgctaca ttcatcatac caaaatttga aaacggtttc
     3481 tttattattc agatacttca aaaatttctc ctaaaataat aaaaaaatac aaatcaacta
     3541 tgacaaaagg aataatctta gcatctagac caaagatcga aatggtgagg tttctttaaa
     3601 ataaaaatat ccttgcattt tctcctagaa ataagtattt ttaaattaca agactattct
     3661 taaggcgggt aaaaaaatgc caatacgcgt aattcttatc gatgatgaac agacgatttt
     3721 agatggaatg aaacagttga tcaattggtc tgagcacggg tttcaattaa tagggacttt
     3781 ttccagtccg ctgaaagcgc ttgatttttc tttggtacat gcaatcgata tcgtggtcac
     3841 agatgtaatg atgcctgaat taaatggaat cgaattatcg cggctattaa aacagcaaca
     3901 acctgaaaca cagatcctta tcctctctag ctatgatgaa tttgatatgg ttaaagattc
     3961 ttttaaagaa ggcgtcgctg attatctttt aaagcctcga ttgagtcctg atttttttct
     4021 aaattcctta actgccgttt cacaaaaaat caaaaaaaag cccaacaaaa gcccaatcac
     4081 caatcgttat gagcagatct gcgagaatct ttcacagcag attgctggac aaactcgtcc
     4141 attgcttgac cctcttcttt ttgaacacac cttgtttttc tgttatatac cgaaaaacgg
     4201 ccattcagtt caaaacaagg ctctaaacaa aaacagtcga tcacccattc attgatggat
     4261 agcgacgatt cgtttactat ttatcctgtt tctacctttt cggaagaatc cggctatgta
     4321 atcaatactg attccaaaga tacacttagg aagtttgttc aaaagtttcg tcaagaagtt
     4381 tttccaggtg atttttttgt tgtttctgat tcttttgcaa tccaagatat caatgaaata
     4441 ttccaagaga tcagaaattg caccaaagga caacgtttct atcataaggg aaagaacctt
     4501 gcttatcagc atgaacttct tccgttatta accaaccacg agcagcaagc aagtagttat
     4561 ttaacaaaaa tcgttcataa agactacgct ttagctgtca aagaacttga gaatttcttc
     4621 acgacgatat tggaacagcc tattgatcca gcttatttga aacatgaggc aatcaatcgt
     4681 ttctatgcat tactcaacgc tttggctgac gagcatgttg ggaatgaaga actttctttg
     4741 ctcaagatcg cccttccttc tttattagcc gatgctgagt atttcgaaga tttttctatt
     4801 cttgtcaaag aaacacttga gaaactcacc cacttttctg caaatgcaaa aaaagacaat
     4861 ttcgatatct tgactttgat ctacgagttc gtccaggaaa attatgagaa agaaatcaat
     4921 ttacaacttt tatccgaaaa atatcatttt tcatatagct atctctcagc catctttact
     4981 gaaaaatttg gtatcaactt ttcaaaatat ctaaaaaaag tccgtatcag taaagccaag
     5041 ctctttttga cggaaacacg gcttactttg acggaaatct gtgagaaagt cggctatacc
     5101 gaactgggtt atttctccag agtttttaaa gaagagacag gaatgacacc ttctcaatac
     5161 cgtaaaggaa cttttgtaaa atgagaaaaa aaatcaaaga gcatgaactc tttgccaaac
     5221 ttctgttcat tttgttcatc ggtctttttc tgcaagccat cgtcatttct ttgtttattt
     5281 atcatcgatc aagggatgcc tatatccagc tgttcaatca atcgaatgat gtggtactaa
     5341 aaaagattca atctgaattt gaaagtttga atgatacaat cgagaataca ttagccgctt
     5401 ttgattctaa tccagctgtc aaaagctatt tttccaatga tccagcccaa catatggaac
     5461 agcttcagca actaagaaca atccaaaaaa tgaatgactc tctttcaaaa atccatccaa
     5521 tgatcgatta cgatgtattg atctttggag aaaatggaag aacttttgtc ggaaacgaca
     5581 tgctcactgc cgtatctgcc gattcttttt ttcaatctgc gattgctcag agagtgaatg
     5641 aacgtgctgc tgatacacaa atgctttttg cacaccacgg attgactctt cgcgataaga
     5701 aagcacccag cgtcttcttt gtcaaaaaac tgaaaaatac attgaatcac gtttacggat
     5761 atgctgtttt atcgatctca tccaagcaac tagcgaatct ttttcaatct gtagtaaatc
     5821 ctgagatatc gaagatctcc ttcatgaacg aagaacagac gatcatcgca tcaaatgaag
     5881 aaaatacaat tgggagccga tcaatgattt tcaaaaaact aacagtaggt gaaacaacga
     5941 tttcaaatgg acagcagttg acccgtcttc ctctgtaccg ccaggattgt acattactca
     6001 gtcaagtcga tcttcattct ttatctaacc aaatgggcgt gatttttccg attattttgt
     6061 ataatatcgt gacacttgct tttgctggct cattggtatt tatgtatttg gatcgacaca
     6121 caaaatcgat ctaccgcttg attgattcgc taaaacggct agaggaagat ggcttaaaag
     6181 ctactgttcc tgtacaagga agccatgaag tccaattgct agggaatacg atcaatcaat
     6241 tgctaagtaa tgctcagcat cattatgaac agacgatcca agacgaaaag aagaaacgtt
     6301 cgcttgaaat ccaaactatg caagcacaga tacagcccca ttttatttat aatacgctga
     6361 ctagcttgaa atttttgatt tggcagaaaa aaacagatga agcagttcaa ggaatcgaca
     6421 gtttcattac tttactaaga agtacgattg ggaaaaaaga agaagtgatt ccagtcaagg
     6481 aagaaatcaa aagcgtacaa agttacatcg atcttttgag tatgcgatat ggcgaaagaa
     6541 tctcggctaa aataatgatt cctgatgaac tgcagtcatt atctatgccg aatatgatcc
     6601 ttcaaccaat tatcgaaaac gcctatcttc atgcttttca caataaaacg caaggattca
     6661 tcacggtgta cggcaaaaca aaaaatcagc ttcttttatt cgaagtgatt gataacggcg
     6721 atggcttcga tactgaaaat accaaacaaa aaaatgatca tttttcagga atcggcatca
     6781 gccatgtaga tgagcggata cgcctaatgt atggcgatgc atatggctta acgatccaat
     6841 cagtgattgg gacaggaacg actgtaacga tttgtctacc gcttcttcct aaaaatcaat
     6901 cagaatatca aaaataaaga atagccaagc gctgattttt ttattttaag ttaaataaat
     6961 caatcagtat tcttgacttt catctacgcg tctcttctac tgtcagcact ggataacagc
     7021 ccaatatttg actttctcct ccgagcatct tgatttcttg gagcgcattc tctactaatg
     7081 tcattggacg gtccaacaac aaatcgatca cgaaaaaata ttctcccaag ctagttttca
     7141 atggtcggga ttcaatctta cttaagttga tttcccgcca gccaaaagct gccagcattt
     7201 tatgaagcat ccctggccga ttagcaggta gtgtcaagat gacactcatt tttactggag
     7261 ctgactgctg gctggtcatc tttcggtcac cgacgatcca aaaacgtgtc tggttcaact
     7321 cattatcttg gatattctca gctaagatct ccaatccaac atgctgtgct gtttctaatg
     7381 aagcaatcgc tgctgcgtct tctttcggat gttctgctac atacattgct gcagcagttg
     7441 ttgattctgt tgctactaaa ggaacattag gataatgcgt ttctaaaaac tgttgtgatt
     7501 gtgctagtgc ttgtggatgt gaaaggattt ttgtaatctt tgttgctgga ttgcctaaaa
     7561 gctgctgctt gataggaaga acgatttcac ttttaacttc gacttctgga tgtttggaaa
     7621 gaagatcgat tgtgtgatga acagctcctt ccaatgaatt ctctacagga acgacagcca
     7681 gatcgacttg tttgcgaaac aaagcgcgca aacaaacagg gatggaagca tacgcagtca
     7741 attgttctgt aggaaatagc tgacaagccg cctgataagt gaatgaactt tctggcccta
     7801 gatagctgac gttcatatgc ttttgatcct ttctataatg gtatcgatga tcttttctgg
     7861 tgtttgattg gtcgtgttga ttcgatgtgt cgcactttct tcataccaag aaagtcgttg
     7921 tgccaataat gcttttattt cttctcttgt ttttccaaga gctaaaggtc gaatagacgt
     7981 ttcatcttgt tggatacgat caactagaca gtccgcttct gcctctaagt aaagaacaat
     8041 cggctgtgtt tttaaaaaac gccgattttc tgcactttgg acaatccctc caccagtcgc
     8101 gataattttg tcttcatttg acagctttct taaaatatct gactccactt ttcgaaagct
     8161 tttttcaccg taatagtgaa aatattcggc aatcgacaat tggatatgtt cctcaatctt
     8221 tgtatctaaa tctacatact ctttttgtaa acattgagct aaccctttac cgattgttgt
     8281 ttttccagcg cccatgaaac caatcagcaa aatgctagcc atgagcttct cctcctgaca
     8341 caagttctgc taaatcgtca aaaaatgccg gataagagat tgaaacagct tcagctcctt
     8401 ctagttcgca aggtccatca gctatcaaag cagctacttg cagcatcata ccgattcgat
     8461 gatcgcctct gctggacact tttgcgccat gcagaggtgt cggcccatgg atgatcagac
     8521 cgtctgctgt cgcttttatc tttgctccca ttttctgtaa ttcttctgcc accgcatcaa
     8581 ttctgttggt ttcttttact tttaattctt ctgcgtcttt gatgatcgtg attccttctg
     8641 cttgagtagc cactaaagct agaatgggca attcatcaat cagacgcgga atgatttctc
     8701 caccaatcgt tgctttcttc aaatgactcg tcttgacact taaatcagcc gattggttct
     8761 gttcattgtg attcgtctgg gtaatcgctg cgcccatctc ctccaacaca tctaagatac
     8821 cagttcttgt tggattgacc ccgacatttt ttaacaacag ttggctttcc ggaacaagaa
     8881 gtcctgctgc tagaaagaaa gcagctgatg aaatatcacc tggaacagtt atctgttgac
     8941 cagttaattt ttgcggtccg gtcactatga tcgttttatc ttccactgtg atccttccgc
     9001 caaattgacg aatcatttct tccgtatggt tacgggaacg ttctttttca acgattacgg
     9061 atgtgccttc tgcttgtaat gccgcaaaca gcaaagcaga tttgacttgc gcactggcta
     9121 caggcatatt gtatcggata ggtgataaag agcgggttcc tgtcacagtg attggtagat
     9181 actggtcatt ttcttctcct tgcaagtcag cgcccatctc gcgtaaaggt tccatcactc
     9241 gccccattgg acgtttagac aacgaagcat ccccgaacag agtagtcgta aaaggctgtc
     9301 cagccaaaat acccatcaat aaacgtatgg tcgtaccgga gtttcccatg tcaattgatt
     9361 cggttggttg gacaaatgag tggctaccgc gaccatgaat cttgatcacc tcttcctctt
     9421 cttcgatctc gacacctaat tgttggaagg catgtaaagt actcagacaa tcttctgcgc
     9481 gcaaaaaatt ttgtatagtc gtcgttcctt cagcaattgc tccaaacatg atgctgcgat
     9541 gggaaattga tttatctgct ggtatcctaa cagtccctct taatccatgt atttgttgta
     9601 ataattgcat ttatccagcc tcctatttga tccagcaatg ataactggta ttagacataa
     9661 tgattctttt tgcttgtaac aaatcctgtt ggtttttaaa actgatttgc agtattccta
     9721 aaatatcttc cctggtctct tggatcttca aattaatcaa agaaactccc gcttttccga
     9781 tcagtccagt tacttctgca ataacgccag gttcatctgg cacatcgata aataaatcaa
     9841 aaaaggcagg aatcgcgcct tgcttatgga caggcaactg gtctcgactt tcttttgccc
     9901 gattgaaaaa agaaaagatt tccgattggt tctcagtcat gatccattct gctatttgtg
     9961 tcatttcttg ttgccaatct gccaatcgtt ccaataatat ctgcttattg ctcaacaaaa
    10021 tatctgtcca catgacagga tctgaggaag cgatcctagt gatatctcga aagcctcctg
    10081 ctgccagttg tttggctcgc ggatactctt gattgaattg ttctgcctga ttgactaagc
    10141 cagctgccag aatatgtgga aaatgactta gcattcctgt tatacggtca tgttctcttg
    10201 ctgtaagagt tacatatttt gctttggttc cgcaaaatag ttcttgcagt ttttcaacat
    10261 cttttttcgt cttttccaaa ggtgtaaaga tgtaataggc attttcaaat agtttagcat
    10321 ctgctgcctg tatacctgat ttatgagaac cagccattgg atgtccaccg acaaaccgaa
    10381 gatttttctg ctcagcggat gtcacgactt gctgcttcgt actgctgaca tccgtaatga
    10441 tgacgtgatc agacaagttg attctttcaa ggacatcaag ataagctaag gttgtacgga
    10501 cgggaacggc taataagata acgtctgctt gttctgcacc tgtttcaaaa tcacttgcaa
    10561 cgtaatcaac gatctgctgt tctactgctt gctcacgggt ttttgactga ctatcccaac
    10621 caactactat cagttctgga ttggtctgac gaatacaaag tgccatagaa gcaccaatca
    10681 gtccaagccc cacgataaaa acatgttgtg ccatcttatt tgcccccttt ttagtaatgt
    10741 ttcaagtagt cacggtactc cttcactgca gctttcaact caacaagcga atcacttggg
    10801 aattttgaca atagctctgt cgctaccaca gtggctacaa cattttccgc aacgacgcta
    10861 gctgcaggaa ctgctgtact atccgaacgt tctacacttg ctttgtaagg ttcttttgta
    10921 tcgatatcaa cactttgaag tggcttgtac aatgtaggaa tgggtttcat gaccccgcga
    10981 atgacaagtg gttcgccatt ggtcattccg ccttcgaagc cgcctagatt attggtacgt
    11041 cggaaatagc ctctttcttc ttcccatagg atctcatcca tcacttctga gcctggtaat
    11101 gaaccagaag tgaatccgac cccaaattct acgcctttaa aggcattgat actaaccaca
    11161 gcttgtgcga ttttggcatc tagcttcgtg tcccattgta cgtagcttcc taatccagct
    11221 ggaacgcctc caacgagcac ttctacaatt cctccgatcg tatctccatt tttctttgtc
    11281 tgatcgatca aatcttttat tctttgctca actgctggat caacaactcg tacttctgac
    11341 gcttcagaaa tttctttgat ttcttgaatc gagatatttc caggtatttc tgcttggatt
    11401 ccaccaagac aaatcacgtg tcctgctacg atgatgtcaa gttcttccag aattttcttg
    11461 gcaattgcgc cgattgctac acgcatggtc gtctctcttg cagaggaccg ttcaagcaca
    11521 ttccgaagat ctcgatgatg gtatttcata ccgcctacca aatccgcgtg tcctggacgc
    11581 ggacgtgcaa ctcgccgcag tgattggtct ttttcaggca cttctgctac agacatgaca
    11641 gttgtccaat ttttccaatc tttattttct accactaaag tgacaggtga accaattgtt
    11701 ttgccgtgac ggatgccaga cgtgatccga acacgatctt tttcgatctt catccttcct
    11761 cctctgccgt aaccagcttg tctgcgagcg agttcgtgat tgatttcttc ttctgacaga
    11821 ggtaatcctg ctggtagtcc ttcaataatg gctgttaatt ctggtccatg ggattctccc
    11881 gcagtcatat aacgcatctt acagtcctcc taagtaatct ttgaatgtct ctgtgggaac
    11941 aggaacgatt tttgcttgcc caatcttttc tagcaagatg atattcaatt ggcttcctct
    12001 tgctttctta tcatgggtta tcgcgtggaa taattcatct ggatgactta gatcgtacgt
    12061 aatcggcaga tggaattttt gaagtatcct ttctaaagca gctgtcgatc cagttggaga
    12121 caagccgatt ttttctgcat gagaagtgat ggctaccatt ccaatagcta ctccttctcc
    12181 atgactgact accccatatc ctgctgtatt ttcaattgca tggccaattg tatgaccaaa
    12241 atttaaaata agtcgatttc cttggtcaaa gacatcttct tccactactt ttcgtttgat
    12301 ttccaacgta gcagtaatga ttggaacagc atgttccaga agatcttttt cgtctttcag
    12361 ctcgttcagc tgtttccaaa gcgttgcatc tgctatagct gctgatttga tgatttcagc
    12421 gattccttct cgtaaacgac gtaccggcaa agtttttaga acctcaggat caatcaatac
    12481 accagctggc tggctaaatg ttccgacaag gtttttcgct ttgtttgtat tgactgctgt
    12541 cttcccgcca atactagaat ctacttgtgc aagtagcgta gtcggaattt gaacgaaatg
    12601 gatcccacgc atgaacgtcg aggccacgaa tgctgctaga tcacccacca ttcctccacc
    12661 aagtgcaagt atcccatcgc tgcgggtaaa atcattatct gctaaaaaat cgtataactc
    12721 agctgcttgt tctaaagatt tactggtctc acccgccggt acgattgaaa ggactggttc
    12781 aaaattagct tgtctcaatt ggaacatgat tttttctgca tatagtggag caacgtttgt
    12841 atcagtgatc acagctactt tttgaggtct ccaaatcgtt tgaagccatg atccagcctg
    12901 ttctagtgcg cctttttcaa tatgaatatc gtatttttgg ttatcaacat gtacagtaag
    12961 cattcgtttc acttctttct tttaaaaagc tggaattaat cgagtgtctg aatcttttcc
    13021 attgcttctt tcatgatcgc aacttctttc atcatgcgtg agtaagtctt ttcattcaac
    13081 gattggggac cgtctgacca agcatttgca ggatcaggat ggatctctac gatcatgcca
    13141 tctgctccgc ttgccacacc cgcacgagcc attggtggta caagttccca aattcctgta
    13201 ccatgacttg gatcaacaat cacagggaaa tgagttaatt ttttcatcaa tgggacagca
    13261 cttaaatcaa acgtattacg tgtcgctgtt tcgtaagtcc gaatcccacg ttcgataaaa
    13321 atgacaggag atttgtcttc gactgcaatg tattctgcag cattaagcca ttcattgatc
    13381 gtaccggaaa ttccacgttt caatccaaca ggtttacctg ttttaccgac agcagatagc
    13441 agtttaaaat tttgcatatt acgtgcgcca atctgtagga tatcgctgta ctcagccacc
    13501 atatcgatat gcccttcatc catcacttca gtaatcactt tcattccaaa ttcatcagcc
    13561 gcttgacgga tgtatttcaa tccttcttct tctaaacctt ggaaagcata tggagaagta
    13621 cgtggtttga aggcaccacc tcgcagaatt tttgcgcccc cggctttggc cattcgcgca
    13681 cattctctga tttggtctaa tccttcgata gaacaaggac cagccatcgt cacgaaactg
    13741 ccgtcaccaa tttttactcc gtctacatcc acgactgtat tgccaggatg gaattctcga
    13801 gaagtcaatt tgtatgtgtt taaaatacgc acagcatttt ctactccttc atagcgtgta
    13861 aatgctcctt cttgtaaact tcgcgtatca ccttttagtc caatcactac tcgttctgtt
    13921 ccttgatcga ttgagacttt gaatccttct ttttcgatat gatcgacgac tttttttatt
    13981 tgttcttccg ttgcttcttt tttcataatt actatcattg tttttcccgc tttcttttgt
    14041 ttacttatct atcttggctg attttctcta ctttttcaag gtggttttac attaattcct
    14101 actaaatgac cgtgtcctgt tgttctcatt ttcgctcctt ctttcctact tatgacccag
    14161 ataatcaaca aaaaaagatg tccctgtagg aaattgcctc tacagtgaac atcttcaacg
    14221 agccttaaaa agcgctgcaa aaatataaaa tagccactat agatgaattt ctctacgtgg
    14281 ctgtaagtcg tgtttaaaaa tctttagcca tcatagatac aaacctggtt tgtttgtacc
    14341 cacgaagtca tgaatacaaa cctatctaaa atagctaaag taatacgtat tcagttttgt
    14401 aagttttcta gatttcataa aaaatcgctc caaactgatg taagaattgt acctagtata
    14461 gacataaaaa aatcgactgt caatcatttt tatgaaactt tttttaattt tctgatagtt
    14521 aactttgttt ttcagaaaaa taacaattgg ttttattgaa gaaaatagtc atgaacaaaa
    14581 gtatctgaga acttttttac tctcttgttc atgacatata gaataaagca gctttgtctt
    14641 gtaaactccg tttttcaaat aataatctaa agattgctac tgaataataa agccgatttc
    14701 atggtcctct tcgctgctga ttcggtaagg tgactcaaca tccgctcccc agctattgat
    14761 acccccgact cctcttactt ttgcaaaaat cgtaagaacc gttcgtcttt ctggcggtag
    14821 ttcttctata tgtgttgcct gttccagttc ttctgctttg aatggtaaag cggaaaaagc
    14881 aaatggcgta tcctgctgtt caaatcgcaa cgaaaaatct tcttgatctt tatccgtatt
    14941 atccaacgtt tgatttcttg ttagttctac ccatttcgtt tccatatgca tgccgcattc
    15001 ttggggaaca aggtatgggg aaacggggag tcctgccact ttataaatac cttcgacacc
    15061 accagccatc cgatccggat atgtttcccc tgataggcct tcatactcaa aaaattttgc
    15121 tttcgttggc ataatgaacc ttaaacccaa tgcgggtaat tccggtaatc ctttttgtcc
    15181 ataataatgc atattgacaa gcattttacc ctctccagcg atttggtagg aaattgtcac
    15241 ttgggttttt ggtactgtgt tgatttccag tgtaaaaatg atttcaaccg tttcagcgta
    15301 ttcattactt gaatattgat tatttactgg agcaatcggc aaatcgatct ttttattgtc
    15361 caccagtact tctatttctt tgacttttgg atacaatccg gctcctaacc acataccgga
    15421 tttaaatcca aatccgctac ctctgtcatt atcggtcgtt gctcgccaaa aaactggaag
    15481 tgtttcccgg tatagccatt cttttccgtt tttattgagc gattccagtc cgcctcttgt
    15541 ataagaaaaa atataatgcg tattccccga tttgacacct aatgtacagt cgccgaagac
    15601 gattgcaact ttttccgtat ccatatgact tttatttact gtatttttca taataatatc
    15661 ttacctcctg catggcgggt ttttcttgtc catctgcaaa aacgatccca ttccctgaga
    15721 attcatagtc acttggttta tcgtcaaagt caccgccata gcgcatcact tctctgcctg
    15781 tgattggatc agtcacttgg atcgcctgat ctttaaaatc ccatatatag cctccttggt
    15841 acatttcata acgatcaagc aacgtcatgt aagaatccat tccacctaac gaattcccca
    15901 tgtcatgcat atattcacat aagatgaacg gtttttccgc tttattttca aggtagtcaa
    15961 tgatctcttc tggtggcgca tacatgcagc tttttacatc tgaaatcgaa tcttcgaatg
    16021 ctggatttgg aaaattccct tcataatgga caagtcgatc ggggtctact tttttgaagt
    16081 aatcgttcat ttgtcgaatg ttttcttccg cataagattc atttccaaga gaccaaaaaa
    16141 gaatacttgg atggtttttt aatgtttcga aattcgtttt tgctcgatca agaacagccg
    16201 cctgccactg aggtactgca cctggtacgt tgtaagaagg ctcaaatgcg cccatttttt
    16261 gccatgagcc atgggattcg aggttcgttt ccgccatcac atggattcct gcttggtcgc
    16321 ataaataata ccaagtgatc tggttggggt aatgagatgt ccgtacgccg ttgatctttg
    16381 cattttttat gatagccaaa tctttttcca tatcttctat agtgatggcg cgtccttttt
    16441 tcggatgcca ctcatgtcga tttaccccgt tgataatcat ccgttttcca ttgaagtaga
    16501 tgattttatc tttgatttcg attttacgaa aaccgaagga atagtcaata tactccgtta
    16561 ctcttttttc ttcgtctatc gtctccaatt caagcttata taaattgggc tgaaaatgcc
    16621 cccacagtgc cacattttca aatccatcga tgcgaatcgt catttgctct tttaacggat
    16681 attgctgttg atagatttcc ttcccatcag gatctagtat cgctacattc agctgactgt
    16741 ttttggctac ttgctcaaaa gacaaatcta cttcaagttt gccattttga catttgtcat
    16801 ctaagcgagg tttgatccaa agatcttcta aatggttttg tcctcgagca actaagaaga
    16861 catctctgaa gatcccaaaa aatcggaaaa agtcctgatc ttccaagaat gcagctgtac
    16921 ttcttttgta aacctccaca gctagaatat tttcttcttc caaataaggt gttaaatcaa
    16981 attcagacgg agtgaacgaa tcttcggcat acccgataaa atgaccattc aaccaaataa
    17041 acattgcttg ttctacacca gcaaaatgaa tcgagatttg ttttcccttt agaccttctt
    17101 ctaatcgaaa agtcgtcaaa tacgaaccaa ccggattgtc tttagcagct gaaaagatcc
    17161 cttccgcctc tttctcaggg cttgtcgtga aagggggacg gcgaaataca tgtccctccc
    17221 acggatacat cgtattgatg taatggatct tgtcataatt tgctaattca atatgactag
    17281 gaacagtgat ttcatcaaaa gaacaggcat caaaatcttt tttataaaat gtttttggtc
    17341 gtaccgaagg atttggcgaa taacaaaaac gccatgatcc atttaaagac tgtttaaggg
    17401 aggatgtggt ttctacttct tcccttgttg cataacaaac atgatcgcta tgtgcatttg
    17461 attggttcac tctaaaaact tgtggatcat ctaaccattt tatatttgct ttcatacttt
    17521 tttccttctc tctcataact ttttgaaatg aagcagttct gtttggaaat caccttgaaa
    17581 atcggggaag taaagtccaa ctgtcatcaa ttcggccccc gaaaatatcc gcttcgaggt
    17641 ctgttcctga taaagtgcct catcatctaa ccccatcaga tatacttcat ggaacgctgg
    17701 ttgagctgaa gctagtatcc tccctaaaaa cacaatagct tcatcttgtt taggagacac
    17761 aaacatccat gcggcaatat tttcttcaaa aggactcgcc aaacgataat aatggccata
    17821 ctggatcacc ggacgaatcg tttgatagga tataatttgg tcttttactt gctttttttc
    17881 ttcaggagac agctttgtca aatccagttc ataaccaaaa acagcgctca tagctgtttc
    17941 tcctcttgtt ttcaacgaag tagatctgtc ggtctgatga tttggtacag ctgatacatg
    18001 agctgtgatg gacgaaatcg gataagcaag gcttgttcca tattggattt tcatacgctc
    18061 cactgcatcc gtgttatcac ttgtccatga ctgcggcata taataaataa acccggcatc
    18121 aaaccgtcca cctccaccag aacagccttc ccataagatt tccggataat cagttgtcaa
    18181 atgttcaagt agttcataaa gcccgagcat ataacgatgc gctacttctc cttgtctctg
    18241 tgggtcaagg gtaatcgaat agacatctga aagcgaacgg ttcatatccc atttgatgta
    18301 gtcaagagga atcgtatcta aaatctttct catttgtttc tcaatcgtct gccgaacatc
    18361 taaccttgta aaatccagta catgttgtga tctggaagca gaaggcattc tacctggctc
    18421 ctgcataaga aaatcaggat gtgttcgata cagttcagaa tcaaccgaga tcatttcagg
    18481 ttcaaaccat aaaccaaatt tcaatccttt gctatgagca taatctgcta tttcacgtaa
    18541 tccatttgtc aacttgcctt catactcgaa ccagtctcct aatgaagaat tgtccgcatc
    18601 tctttttcca aaccagccat catctaatac gaacatttcg atgcctagct cctttgcttc
    18661 atcaatgatc gccttgattt tttcactatt gaagtcaaag taagtggctt cccagttatt
    18721 gaccagaatc ggccgttcag caaattgatg acgacctctt gcgattcttt cacgtagcaa
    18781 ctcatggtgg atctgactca ttttgttcaa tccctgactt gagtaagaaa ggatcatttc
    18841 aggtgtttga aaagactggc ctgcattcaa ttcccacgaa aaacgatggc tgttgatccc
    18901 accgacgact ctcaattgat tgatctgatc tttttcaagt tcgaaagaat ggttgccgga
    18961 ataaacaaat tgaagtccga tcgcttctcc agtattttct gtcgtatgat gatgaactaa
    19021 agcaataaag ttattcatat ggtgactgct cgttcctcga cggctttcaa atacttttgt
    19081 tccagataaa acagattgcc gtgaaatctg tctttcattg acatgtgctc ctggcaaagc
    19141 aatgacttca tcaaatcgcc tagtatgggc aaagtctagc tggaaactag ccgctttttc
    19201 tagtttgatt gtttctccgg tttcatttct tatctttaca gatcgtgtga tcactgctct
    19261 atcagtaaat atggtataga acaaatcgaa ataaatcgct gtttctctat ccttaagtga
    19321 aatcaccaac gtttgtgcct ctgacttgtc catcacataa gtttgaggca agccttcgat
    19381 ctctggcttc ccatctgtaa tataatggct gtcatatctc agatccagta agtctgatcc
    19441 attcttgcgc tgaatgatcg atgcgggcgt tcgaaagtcc atgctgccat gagaagagta
    19501 ttcttgcggt agtgtatctt tcgacagaga ccggtcagga tttaagggaa catttcctga
    19561 aaatccacga tctcttcggg gataattttt attgtctttg tactgcttga ctggtttgcc
    19621 aaaataaata tgcgccaata cattgctttc ttctatcttt atcagataag aaagaaatgt
    19681 atttcgtaaa tggaagactc ggctcttttc atcaaataag atgaaatttt tatctgtttt
    19741 tctatgcgta atatccatca tttcactccc aacaaaacgg aaaccgttta ctttttttta
    19801 taattcctgt atactgttta ctaaacaatt ttgtcaataa aaatttttta tttttttgag
    19861 gagtgtgtaa aaatggttgg aattagagat gtcgcacgaa aggcaaatgt ctctcctgct
    19921 acagtttccc gtgtgttgaa taacgatcag acgatccatg tggctcagac tactcggcaa
    19981 cggatagtag aggcagctgc tgcgttggat tatgacatca gtactcgtaa atatatcaaa
    20041 aagagaatgc cttcgattgg tgtgatctct acgatcggca aagcgagcga agaacaggat
    20101 atctattaca aacatttgcg agtagggatg gaagaagaag ctcgacgtct gcatttaggg
    20161 atgaatcgaa tctataatct atctgataat cctaaacaat gggaagatct agatcagtta
    20221 ggtgcggtga tcgttgttgg gactgttacg aaagaatcga ttaccgcctt gttaaaacaa
    20281 aacatgcaaa tagtcgtcgt ggataaccct gacatccagc aagaggtcga tatggtgtat
    20341 gcagatcttg aacggatgac taaaaccgta ctggaattgt tcttagaaaa tggtcataaa
    20401 agaatagcct atatcggggg atataaagtc gatatggatg aattcggtgg gaagcagatt
    20461 tctataaatg aaaagaggat gcgtgcctat cagcatttta tgatcgatca tcacttagaa
    20521 aaatatatgt cttatcatct aggtggctgg acagaaaaac aaggtgaggt acttgcgact
    20581 aatctattag aaaatgaatc ccctcttcct actgccattc ttgtcgggag cgatccaatg
    20641 gcaattggtg tctatcgggc attgaaacaa aaaaatatcc aaattggaga agagattgtt
    20701 gtagcaagct ttgataatat cgagacaatc gcaaacctct cccctggctt gaccagtgtt
    20761 caaatcaatg cgaaatcaat tgggcaagca gctgttcgaa tggcattgga gcgaattgac
    20821 ggtatacggg acgaaccaat cattttgact tatcctgcac gattgattgt tagggaaagt
    20881 tttatcccaa gaacaaaaag gtattgaaag agaggttgtg aaaagccgct tcgtttcttc
    20941 atactcaaaa cgaaacggct ttttcacaac ctcttactta tacttattca caaaatccaa
    21001 tgtctgctgg taacaatttt gcgattcttt tagcgtgtaa tcaaattggt attcatgggt
    21061 aatctctttt tttgtatctg tataaaacaa ggattgcacg ggtaccttta attctgtcaa
    21121 ccgattttct aatgcttgac cttgctcctg gaatgagtat gcatttccgt cagttatata
    21181 cgttggcgga aattccttag aaacatggtc agccacacta gcttctttca attgctcact
    21241 cgttttccaa tcttttgttc caatcaacga ccacgcaacg gttttgacga aaaacttcat
    21301 aaatcgatca tccgaatgct gctgtgctgt tagcttcaaa tcaacaggtc cgcaataaga
    21361 aatggttcct ttcagactat cttttggaag tagctgtttg attttcattt gtttagcata
    21421 cgcatcattc gtttgtatag ctgcatattg caatgcgatt tgtgaacctg cactatctcc
    21481 accaaaaaat aattgttcca tgtctagcaa tttgtcgtct ttttcttcag ctaataaatc
    21541 tttgatcagt tcattcactt gaagaacttg attagggtat tctgaatcag gcgctaattc
    21601 ataattcatc gcaaccactg cgatgttggc gtctgaaact aattttgtcg caaattcttt
    21661 gacacccgat ttatctccgc cgacgaatcc tccaccatgt acccaaaata gaacaggaac
    21721 aggccccttg ctgttttttg gatagtagat gtcataagta ttctctttat acttggactc
    21781 atacgtcaaa tctgtttttt tcgccacgtt tttttctgct tgatcgaacg tttttttatc
    21841 agtgatttga acagtatttg aaaacatatg gttgatcaag aatgctccag gtctggggga
    21901 aagctggaag gcaagaaaga ttgcaaacgc gatcccaaga atgattccga agaaccatcc
    21961 gataaattta agaattttct ttttcataag gctccctcag tagttagtat taagcattct
    22021 gattatacca tagtgttatt tcctatcaag ctctcctaga tgatttaatg attttcccca
    22081 aacttcttct gcaatgcttt tgacaaaaga aattttttcc attgttcttc aaacaaaaca
    22141 ttttcttctt ctgttgaagc aaatccacat tgaggactta agcacaaacg atccaaaggc
    22201 agatatcgtg tcgcttcgta gatccggtca atcacttgct ggtgctcttc catttcgcca
    22261 tttttcgtta cagtcaaaat ctaagacaac taatttatct tcagagactt tctctaaaag
    22321 aacaaaactc ccagcacgtt cactatcgta ttctaaataa taggcacgga cattttcttg
    22381 agtaaaataa tgggtctgct acgtcgtcat cccccctgat gccgccaaaa tcgaataata
    22441 atttccgcgt caaacatgta tatttagtgt tgaatcattt gagaatatga aaataaaaat
    22501 ctttttgatc aatcagttaa tcaaattgaa ataacgaaaa atctgagaca gaatgacgtt
    22561 cattctgacc cagatttgat tttgcacaac tcaacagtcc ttattggcaa atcgccaaaa
    22621 taatgtagac taac
//
LOCUS       DADGKS010000043        22633 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.043, whole genome shotgun sequence.
ACCESSION   DADGKS010000043 DADGKS010000000
VERSION     DADGKS010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22633
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.043"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..197
                     /locus_tag="JXV47_001770"
     CDS             <1..197
                     /locus_tag="JXV47_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487812.1"
                     /translation="WFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLIIAIIAVGLV
                     FNAAGVKDILLELFNRIIGA"
     gene            314..811
                     /locus_tag="JXV47_001771"
     CDS             314..811
                     /locus_tag="JXV47_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAX1487813.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            786..1292
                     /locus_tag="JXV47_001772"
     CDS             786..1292
                     /locus_tag="JXV47_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAX1487814.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            1276..3723
                     /locus_tag="JXV47_001773"
     CDS             1276..3723
                     /locus_tag="JXV47_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAX1487815.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            3726..5903
                     /locus_tag="JXV47_001774"
     CDS             3726..5903
                     /locus_tag="JXV47_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAX1487816.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDILFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            5900..6901
                     /locus_tag="JXV47_001775"
     CDS             5900..6901
                     /locus_tag="JXV47_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAX1487817.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            6898..7833
                     /locus_tag="JXV47_001776"
     CDS             6898..7833
                     /locus_tag="JXV47_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAX1487818.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            8078..8194
                     /locus_tag="JXV47_001777"
     CDS             8078..8194
                     /locus_tag="JXV47_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HAX1487819.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            8210..10129
                     /gene="tet(M)"
                     /locus_tag="JXV47_001778"
     CDS             8210..10129
                     /gene="tet(M)"
                     /locus_tag="JXV47_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019117172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HAX1487820.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDRGTTKTD
                     NTLLERQRGITIQTAITSFQWKNTKINIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKIGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     HPNMRVMNFTESEQWDMVIEGNDYLLEKYTSGKLLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     PLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            10248..10415
                     /locus_tag="JXV47_001779"
     CDS             10248..10415
                     /locus_tag="JXV47_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAX1487821.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(10475..10828)
                     /locus_tag="JXV47_001780"
     CDS             complement(10475..10828)
                     /locus_tag="JXV47_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1487822.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            11333..11755
                     /locus_tag="JXV47_001781"
     CDS             11333..11755
                     /locus_tag="JXV47_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAX1487823.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            11752..11982
                     /locus_tag="JXV47_001782"
     CDS             11752..11982
                     /locus_tag="JXV47_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1487824.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            12443..12646
                     /locus_tag="JXV47_001783"
     CDS             12443..12646
                     /locus_tag="JXV47_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HAX1487825.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            12728..13945
                     /locus_tag="JXV47_001784"
     CDS             12728..13945
                     /locus_tag="JXV47_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAX1487826.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
     gene            14251..15444
                     /locus_tag="JXV47_001785"
     CDS             14251..15444
                     /locus_tag="JXV47_001785"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HAX1487827.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            15574..17046
                     /locus_tag="JXV47_001786"
     CDS             15574..17046
                     /locus_tag="JXV47_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAX1487828.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            17129..17917
                     /locus_tag="JXV47_001787"
     CDS             17129..17917
                     /locus_tag="JXV47_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HAX1487829.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(17984..18652)
                     /locus_tag="JXV47_001788"
     CDS             complement(17984..18652)
                     /locus_tag="JXV47_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAX1487830.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            18767..20479
                     /locus_tag="JXV47_001789"
     CDS             18767..20479
                     /locus_tag="JXV47_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1487831.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            20482..22254
                     /locus_tag="JXV47_001790"
     CDS             20482..22254
                     /locus_tag="JXV47_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1487832.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRVTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(22336..>22633)
                     /locus_tag="JXV47_001791"
     CDS             complement(22336..>22633)
                     /locus_tag="JXV47_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage integrase family protein"
                     /protein_id="HAX1487833.1"
                     /translation="KNNKDKYIFISKNGNPISIQAYNQSLRAVSKELNLDKKVSSHML
                     RHSHISLLTELGIPLKAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
BASE COUNT         7203 a         3945 c         4783 g         6702 t
ORIGIN      
        1 actggtttct atcaaacgct caatcactgg tgcttttagc aatcgttgtg attggcttgt
       61 atcttggctt caagcgtgag tttagcaaac tgattggctt tttaattatt gcgattattg
      121 cggttggctt agtcttcaac gctgctggag taaaagacat tttactagag ctattcaatc
      181 gcattattgg tgcttaaata aaaccgttct tttgtggaat ataagtggtt ttcttatgtt
      241 ccgcaaagga atggtacacc aaacgaagtg cggtagggat ttttgaatct ctacaaagaa
      301 aggacgtgaa tatatggacg atatgcaagt ctatattgcg aatttaggca aatacaatga
      361 gggcgaattg gtcggtgcgt ggtttacctt tcccattgac tttgaggaag tcaaagagaa
      421 aatcggcttg aatgatgaat atgaggaata cgccattcat gactacgagt taccctttac
      481 ggttgacgaa tacacttcca ttggcgaact caatcgacta tgggaaatgg tatcggaatt
      541 acccgaagaa ttacaatcgg agctatctgc tctgctcact catttttcaa gcattgaaga
      601 actaagcgaa catcaagagg atattatcat tcattccgat tgtgatgata tgtatgacgt
      661 ggcacgctac tacattgaag aaacgggtgc tttaggcgaa gtaccagcta gtcttcaaaa
      721 ctatattgat tatcaagcct atggtcggga tttagacctt tcaggaacgt ttatctcaac
      781 caatcatggg atttttgaaa tcgtctatta aatctgtcgg tacattacta ctggcagatt
      841 ttctatttta cggggtggct caatcagcta cccctatttt ttatgaaagg attgattaca
      901 tgaagaaaat acgaagctat accagtatct ggtctgtgga aaaggtactg tattctatca
      961 atgattttag acttccgttt cccataacct ttacgcaaat gacatggttt gtcgtgtcac
     1021 tctttgcagt gatgatactt ggcaacttgc cccctctttc catgatagag ggagcatttc
     1081 tcaaatactt tgggattcct gtggctttca catggtttat gtctacaaaa acttttgatg
     1141 gtaaaaagcc ttatggattt ttgaagtctg tcattgctta tgcactgcga ccaaagctga
     1201 cctatgcagg aaaaaaagta acgcttggca gaaaccagcc acaagaagcc attacagcag
     1261 ttaggagtga attttatggc atatccaatt aaatacattg aaaacaatct cgtctggaat
     1321 aaagacgggg aatgttatgc ttactatgag cttgttcctt acaattactc atttctaagt
     1381 ccagaacaga aaatacaagt gcatgattct ttcagacagc ttatcgcaca aaatcgtgat
     1441 ggcaaaattc atgctttaca aatcagtaca gaatccagca tacgttctgc acaagagcgt
     1501 tccaaaaatg aagtcactgg caagctcaaa gcggttgcct atgacaaaat cgaccaacag
     1561 acagacgctt taatatccat gattggcgaa aatcaagtga actaccgttt ctttatcggc
     1621 tttaagttgc ttctcaacga tcaggagttt tctatgaaaa gtcttaccgt tgaagcaaaa
     1681 aatgctttgt ctgattttgt ctatgatgtg aaccataagc tgatgggcga ttttgttagt
     1741 atgagtaatg atgaaatcct gcgttttcag aagatggaaa agctcttaga aaataaaatc
     1801 tctcgtcgtt tcaaaatccg caggttagat aaggacgact tcggctatct gattgaacac
     1861 ctttacggac agacaggcac tgcctatgaa gagtatgagt accatctatc aaagaaaaag
     1921 ctggataatg aaacgctgat taaatactat gacttgatta agcctactcg ctgtttggtg
     1981 gaagaaaaac agcgatattt gaaaatccag caggaagatg aaaccgtcta tgtagcttac
     2041 tttaccatta acagcattgt cggagaactg gacttcccgt cctctgaaat cttctactac
     2101 cagcaacagc aatttacatt cccgattgat acgtcaatga atgtggaaat tgtagcgaat
     2161 cgtaaagccc tatctactgt ccgcaataaa aagaaagaac tgaaagactt ggataaccac
     2221 gcttggcaaa gtgataatga aaccagctcc aatgtggcgg aagctctgga aagtgtgaat
     2281 gagctggaaa ccaatttaga ccaaagcaag gaatctatgt acaagctgtc ttatgtggta
     2341 agggtatcag caaatgatct tgacgaactc aaacgtcgtt gtaatgaagt gaaagatttt
     2401 tatgacgatt taagcgtaaa actggtacga ccatttgggg atatgctcgg cttacatgaa
     2461 gaatttttac ctgccagcaa gcgttatatg aatgattata ttcaatacgt gacctctgat
     2521 ttcctcgctg gtttaggttt tggtgctact caaatgctgg gggaaaatga ggggatttat
     2581 gttggctaca gcttagatac tggacgcaat gtctatctga aacctgctct tgccagtcaa
     2641 ggggttaagg gttcagtaac caatgcgtta gcgtcggctt ttgttggttc gctgggtggt
     2701 ggtaaatcct ttgcgaataa ccttatcgtc tattatgcgg tgctttatgg ggcacaagca
     2761 gtgattgtag acccaaaagc agaacgtggc agatggaaag aaaccttgcc agagatttcc
     2821 catgaaatca atatcgtcac tctgacttct gatgagaaaa acaaaggctt acttgaccct
     2881 tatgtgatta tgaaaaatcc caaagattct gaatcactgg ctattgatat tctgacattc
     2941 cttacgggga tttcctctcg tgatggggaa cgcttcccaa tccttagaaa agccattcgt
     3001 gcagtaacca atagtgaagt acgagggttg atgaaagtga ttgaggaatt acgggttgag
     3061 aatacgccac taagtaccag tatagccgac catatcgaaa gttttacaga ctatgacttt
     3121 gcacatttat tattcagtaa tggttatgtg gagcagtcta tcagcttaga aaaacaactg
     3181 aacattatac aggttgcgga cttggtactt cccgacaagg aaacttcctt tgaggaatat
     3241 accactatgg agcttttatc cgttgctatg ctgattgtca ttagtacctt tgctttagac
     3301 tttatccata cagaccgaag cattttcaag attgtagatt tagacgaagc atggagcttt
     3361 ttacaggtag cacaaggaaa aacactatct atgaagctgg ttcgggctgg tcgtgctatg
     3421 aacgctgggg tatatttcgt gacccaaaat acagacgacc tcttagatga aaaactgaaa
     3481 aataacctcg gcttaaaatt tgcatttcgt tccactgacc ttaacgagat taaaaagacc
     3541 ttagcctttt ttggtgtaga cccagaggac gaaaacaatc agaagcgatt gcgtgatttg
     3601 gaaaacgggc aatgccttat cagtgattta tatggtcgtg tcggtgtgat acagttccac
     3661 cctgtatttg aagaactgct ccatgccttt gataccagac cacctgtgcg aaaagaggtg
     3721 taaatgtgaa accatcaata gtaaacagaa taaaatcaaa ctggacgctg aaacgtctag
     3781 gtaaagtggc aatgacagtg gctttcacac ttgtgattgc catttttctt ttagccatgc
     3841 tgggaacggt ggttcaagct gcgggcttgg tagatgatac ggtcaatgtg gcaaatgaat
     3901 acagccgata cccacttgaa aactatcaac tggattttta tgtggataat agctggggct
     3961 ggcttccgtg gaactggtcg gacgggattg gaaaacaggt catgtatgga ctatatgcca
     4021 ttaccaattt tatttggaca atcagtttgt atgtttccaa tgcgacaggt tacttagtac
     4081 aggaagccta ttccttagac ttcatttccg ctacagcaga ttccattggt aagaatatgc
     4141 agaccttagc tggtgtgagt gcaaacggat tttcaacaga gggtttctat gttggattcc
     4201 tcttactctt gattttggtt cttggggttt atgttgccta tacgggactg ataaagagag
     4261 aaaccacaaa ggcaattcat gccattatga attttgtgct ggtgtttatc ctatcggctt
     4321 cctttattgc ctacgctccc gactacatta aaaaaatcaa tgacttttca tcagacatca
     4381 gtaatgccag tttatcactt ggcacgaaga ttgtcatgcc ccattccgat agtcaaggca
     4441 aggacagcgt ggacttaatc agagatatcc tgttttccat acaggttcag caaccgtggc
     4501 tactgcttca atacaacagt tcagacattg aaagtatcgg tattgaccgt gtggaaagcc
     4561 tgctctccac cagcccagat tccaacaatg gcgaagacag agaaaaaatt gttgcggaag
     4621 aaattgaaga cagaagcaat accaatctaa ccattacaaa gaccattaac cgtttaggta
     4681 cagtcttctt cctatttgtc ttcaatattg ggatttccat atttgtattc ctattaacag
     4741 gaatcatgat tttctcgcag gtacttttta tcatctatgc tatgtttctg cctgtgagct
     4801 ttattttaag catgattcca tcatttgatg gtatgtcaaa acgagccata acaaagctct
     4861 ttaataccat tttgacacga gctggaatca cattgattat tacgacagca tttagtattt
     4921 caaccatgct ctatacctta tcggctggtt atccgttctt tttgattgct tttctacaga
     4981 ttgtgacctt tgcaggaatc tacttcaagc tgggcgattt aatgagtatg ttttctctac
     5041 agagtaacga ttctcaaagt gtgggaagtc gtgtgatgag aaaacctcgt atgcttatgc
     5101 acgctcacat gcaccgtcta cagcggaaac ttggacgttc catgactact ctaggggctg
     5161 ggtctgccat tgttacaggt aaaaaaggac agtcgggttc ggggagttct gcaaggacac
     5221 aagcagatca ctcccgacca gacggaaagg aaaaatcaac acttggaaaa cgtatcggtc
     5281 aaaccatcgg tacagtagct gataccaaag acagaatggt agacactgct agtggtttga
     5341 aagaacaggt taaagatttg ccgaccaatg caagatatgc agtatatcaa ggaaaatcca
     5401 aagtaaaaga gaatgtccgt gatttaacca gtagtatttc tcaaaccaaa gcggacagag
     5461 ccagtggacg caaggaacag caggaacaaa ggcgaaaaac cattgcgaag cgtcgctctg
     5521 aaatggaaca ggtcaaacag aaaaaacagc ctgcttcttc tgttcatgaa agaccgacta
     5581 caagacaaga acaatatcat gatgaacaga cctcaaaaca gtctaatatt cagacttcat
     5641 ataaggaatc tcaacaagcc aaacaagagc gtccagcagt taagtccgat ttttcaagtc
     5701 caaaagtgga acgccaaggc aataccgttc aagaaaaaac cgttcaaaag ccagcaactt
     5761 caaccactac agcagataga acttcacaac gtccaatcac aaaagaacgt ccgtctactg
     5821 ttcaaagagt accactacaa aatacaagaa gtagaccacc aatcaaaacc gccaccatta
     5881 agaaagtcgg taagaaacca tgaagttgaa aactttagtg attggtggtt ctggattatt
     5941 cttgatggtc ttctcactgc ttctgtttgt tgccatttta ttttcagatg aacaggacag
     6001 cggaatttcc aatattcatt atggaggtgt gaatgtttcc gcagaagtgc tggctcataa
     6061 gcctatggta gaaaaatatg ccaaagaata tggcgttgaa gaatatgtca acatacttct
     6121 tgcgattata caggtggaat cgggcggtac tgcggaagat gttatgcagt cctcggaatc
     6181 cctcggtctt ccacctaatt cattgagtac agaagaatcc attaagcaag gtgtgaagta
     6241 tttcagtgaa ttattagcca gtagcgaaag gctcagtgta gatttagaat cggttatcca
     6301 gtcctacaat tatggtggtg gtttcttagg gtatgtggct aatcgtggaa ataaatatac
     6361 ctttgaactg gctcaaagtt tctcaaaaga gtattcaggt ggcgaaaaag tgtcttaccc
     6421 caatcccata gccataccta tcaatggggg ctggcgatac aactatggca atatgtttta
     6481 tgtgcaactg gtaacgcagt atcttgtcac aacagagttt gatgatgata cggtacaagc
     6541 catcatggac gaagcactga aatatgaggg ctggcgatac gtttacggtg gagcttcccc
     6601 gactacttct tttgattgta gcggactgac acaatggacg tatggaaaag ctggaattaa
     6661 cttaccacga accgcacaac agcaatatga tgtgacccag catatcccac tatcggaagc
     6721 acaagctggc gatttggttt tctttcattc tacctataac gctggctctt atattactca
     6781 tgttgggata taccttggca ataaccgtat gtttcatgca ggcgacccaa tcggttatgc
     6841 cgacttaaca agcccctact ggcaacagca tttagtggga gcaggacgaa tcaaacaatg
     6901 agaaaggaag atttaatgat gaaatttaga aaaaatcaga ataaagaaaa acagatacca
     6961 aaggaaaaga aacctcgtgt ctactataag gtcaatcctc ataaaaaggt tgtgattgcc
     7021 ttgtgggtac ttttagggct tagtttcagc tttgcgatat tcaagcactt tacagctata
     7081 gatactcata ctattcacga aacaactatc atagaaaagg aatacgttga tactcatcat
     7141 gtagaaaatt ttgtagagaa ctttgcgaaa gtctactatt catgggagca atccgataag
     7201 tccattgata atcgaatgga aagtctaaaa ggctatctga cagatgaact tcaagctctc
     7261 aatgttgata cagtacgcaa agatattcct gtatcgtctt ctgtaagagg atttcagata
     7321 tggacggtag agccaactgg cgacaatgag tttaatgtaa cctacagtgt agaccagctc
     7381 attacagagg gagaaaatac aaagaccgtc cactctgctt atatagtgag tgtctatgta
     7441 gatggttctg gaaatatggt actggttaag aatccgacca ttaccaacat acctaagaaa
     7501 tcaagttata aaccaaaagc cattgaaagt gaggggacgg ttgattccat tacaaccaat
     7561 gaaatcaatg agtttttaac gacgttcttc aagctctatc ctacagcgac agccagtgaa
     7621 ctttcctact atgtgaatga cgggatatta aaaccaatcg gaaaagagta catctttcaa
     7681 gaactggtaa atcctattca caatcgtaag gataatcaag tcacggtatc gctgacagtg
     7741 gagtatatcg accagcagac caaagcaacg caggtatctc aatttgattt ggtacttgaa
     7801 aagaacggga gtaattggaa gattatagaa taacaaatat tggtacatta ttacagctat
     7861 tttgtaatca cgtactctct ttgataaaaa attggagatt cctttacaaa tatgctctta
     7921 cgtgctatta tttaagtatc tatttaaaag gagttaataa atatgcggca aggtattctt
     7981 aaataaactg tcaatttgat agtgggaaca aataattgga tgtccttttt taggagggct
     8041 tagttttttg tacccagttt aagaatacct ttatcatgtg attctaaagt atccggagaa
     8101 tatctgtatg ctttgtatgc ctatggttat gcataaaaat cccagtgata agagtattta
     8161 tcactgggat ttttatgccc ttttgggctt ttgaatggag gaaaatcaca tgaaaattat
     8221 taatattgga gttttagctc atgttgatgc gggaaaaact accttaacag aaagcttatt
     8281 atataacagt ggagcgatta cagaattagg aagcgtggac agaggtacaa cgaaaacgga
     8341 taatacgctt ttagaacgtc agagaggaat tacaattcag acggcgataa cctcttttca
     8401 gtggaaaaat actaagataa acatcataga cacgccagga catatggatt ttttagcaga
     8461 agtatatcgt tcattatcag tattagatgg ggcaattcta ctgatttctg caaaagatgg
     8521 cgtacaagca caaactcgta tattgtttca tgcacttagg aaaataggta ttcccacaat
     8581 cttttttatc aataagattg accaaaatgg aattgattta tcaacggttt atcaggatat
     8641 taaagagaaa ctttctgcgg aaattgtaat caaacagaag gtagaactgc atcctaatat
     8701 gcgtgtaatg aactttaccg aatctgaaca atgggatatg gtaatagaag gaaatgatta
     8761 ccttttggag aaatatacgt ctgggaaatt attggaagca ttagaactcg aacaagagga
     8821 aagcataaga tttcataatt gttccctgtt ccctgtttat cacggaagtg caaaaaacaa
     8881 tatagggatt gataacctta tagaagtgat tacgaataaa ttttattcat caacacatcg
     8941 aggtcagtct gaactttgcg gaaaagtttt caaaattgag tattcggaaa aaagacagcg
     9001 tcttgcatat atacgtcttt atagtggcgt actgcatttg cgagattcgg ttagaatatc
     9061 ggaaaaggaa aaaataaaaa ttacagaaat gtatacttca ataaatggtg aattatgtaa
     9121 aatcgataag gcttattccg gggaaattgt tattttgcag aatgagtttt tgaagttaaa
     9181 tagtgttctt ggagatacaa agctattgcc acagagagag agaattgaaa atcccctccc
     9241 tctgctgcaa acgactgttg aaccgagcaa acctcaacaa agggaaatgt tacttgatgc
     9301 acttttagaa atctccgaca gtgacccgct tctgcgatat tatgtggatt ctgcgacaca
     9361 tgaaatcata ctttctttct tagggaaagt acaaatggaa gtgacttgtg ctctgctgca
     9421 agaaaagtat catgtggaga tagaaataaa agagcctaca gtcatttata tggaaagacc
     9481 gttaaaaaaa gcagagtata ccattcacat cgaagttcca ccgaatcctt tctgggcttc
     9541 cattggtcta tctgtagcac cgcttccatt agggagcgga gtacagtatg agagctcggt
     9601 ttctcttgga tacttaaatc aatcgtttca aaatgcagtt atggagggga tacgctatgg
     9661 ctgtgaacaa ggattgtatg gttggaatgt gacggactgt aaaatctgtt ttaagtatgg
     9721 cttatactat agccctgtta gtaccccagc agattttcgg atgcttgctc ctattgtatt
     9781 ggaacaagtc ttaaaaaaag ctggaacaga attgttagag ccatatctta gttttaaaat
     9841 ttatgcgcca caggaatatc tttcacgagc atacaacgat gctcctaaat attgtgcgaa
     9901 catcgtagac actcaattga aaaataatga ggtcattctt agtggagaaa tccctgctcg
     9961 gtgtattcaa gaatatcgta gtgatttaac tttctttaca aatggacgta gtgtttgttt
    10021 aacagagtta aaagggtacc atgttactac cggtgaacct gtttgccagc cccgtcgtcc
    10081 aaatagtcgg atagataaag tacgatatat gttcaataaa ataacttagt gtattttatg
    10141 ttgttatata aatatggttt cttgttaaat aagatgaaat attttttaat aaagatttga
    10201 attaaagtgt aaaggaggag atagttatta taaactacaa gtggatattg tgtcctgtat
    10261 gtggaaataa aacacgatta aagataaggg aagatactga attaaaaaaa ttccccctct
    10321 attgtccgaa atgcagacaa gaaaatttaa ttgaaataaa gcagttcaaa gtaactgtga
    10381 ttacagagcc agacgcaaag acgcagagcc gataaaatga gattaataca atctcatttt
    10441 atcggctctt tccgttatgt atggattctt ttaattagtc ttcgatgttt cttgcttcgt
    10501 tgataccgct ggctaaagat tccattaagg atagttcttt gtctgtaaag ctatccatgt
    10561 atttctctat ctgtaatcgt cgggtgcttt ttaccaagtt attagcaggt aagaaaaatt
    10621 catcaacgga aacatgaagt aacgatacaa ggtcataaag aacttgtatg ctggggtgtt
    10681 gccctttatt ttcaatatta gttaagtacc gtgggtcaat ttcaatcaat gctcccactt
    10741 gttcacgagt taaacctcgt ttcaatcgag cttctttaat ggctaaacca aaggctctaa
    10801 aatcatattt atcttctttt ttacgcatag tagaccacct ctatacattt tattgttcct
    10861 actgaattaa aaacaggtat agaaaaacgt gttatatggt ttataggttt atatttaata
    10921 aaaagcacta ctaaacgcca ataaaaaaaa ccgttatatg gtagtgctat ttacgctgtt
    10981 aaaatattgt atattacttc caaatggcgg tttgttggag gtcaacgtcg ccatgaagta
    11041 catcatatac aataaatttc cttacattgg gttcttgtca aaaaaagtcg tctatctgca
    11101 atagataagt acgtccacca atgtggtttt ataaatcata tagatagaat aacagaagca
    11161 tgtaaacaga gaaataaatc tgtttatatg cttttttggc tattcagaac ttttttacaa
    11221 agtttattta tcagtaatgc aacaaatccc cctttcacat tgggactaag agtgaaagga
    11281 gataaacgag caaggctcac ttcctttcct agacagaaag ggggtgagaa acatgaaacc
    11341 atcttctttt cagaccacaa tagaaaatca gtttgactat atctgtaaac gtgctatgga
    11401 agacgagcga aagaattata tgctttatct ttcaaggatt gcaaagcgtg aggtgtcctt
    11461 ttcggatgtt ggcgattatc ttgttagcca gtttgcgaca acagataact attcaactga
    11521 ctttcagatt tttacactca atgggttatc agtaggcgtt gaaaatgatt tgttgagtga
    11581 agcattacgt gagttgccag acaagaaacg tgaaattcta ctgctgtttt actttatgga
    11641 catgagcgat tcagaaattg cagacctgtt gaaattgaac cgttctactg tctatcggca
    11701 tagaaccagt ggactagcct taattaaaaa gtttatggag gaatttgaag aatgaaaaca
    11761 caatatccta tgattccctt tcctctcatt gtaaaggcaa cagatggcga taccgaagcg
    11821 attaaccaga ttctacatca ttacagaggg tacataacga agcgttccct acgacttatg
    11881 aaagatgaat atggcaatca aagtatggtc gttgatgaag tcttacgtgg aagaatggaa
    11941 accagactga ttacaaagat tttgtcattt gaaattaagt aatatcctct ctcctttcgt
    12001 ggaagcgtgc taaaccattc cacgcttccc gaacagggag gtttgttatt ccaccaaagc
    12061 atattgagct ttcaatgtgt tttgataggc taacgagcca ttgttctttg aaaactgaat
    12121 aaaagtaatc gaatacgttt cgataagaaa agagccaacg gaactaaccg ccatgaccta
    12181 tcttataaag atagcgagcg attcatgtta gtgatccgag aagcaatctt tagcaggatt
    12241 gcctgcaacg acattcttat cgtgataatg atactcccat acagtcaata gtccgagcgt
    12301 gataaaaccg tcgcaggcaa tgagtatggc tacatgagaa ccatgcaggg gtggaactcc
    12361 cgtgagcttt gctaaagctg ttcgattgct ggtaaaacaa cttttatgaa atccaaataa
    12421 gtgatttgga aaggaggatt ttatgaagca gactgacatt cctatttggg aacgttatac
    12481 cctaaccatt gaagaagcgt caaaatattt tcgtattggc gaaaacaagc tacgacgctt
    12541 ggcagaggaa aataaaaatg caaattggct gattatgaat ggcaatcgta ttcagattaa
    12601 acgaaaacaa tttgaaaaaa ttatagatac attggacgca atctagcgtc gccaaagggt
    12661 cttgtatatg ataaaatagt attaagtcgt atcaaggctc tttccataaa ggaaaggagc
    12721 aaatgccatg tcagaaaaaa gacgtgacaa taaaggtcga atcttaaaga ctggagagag
    12781 ccaacgaaaa gacggaagat acttatacaa atatatagat tcatttggag aaccgcaatt
    12841 tgtttactcg tggaaacttg tggctacaga ccgagtacca gcaggaaagc gtgattgtat
    12901 ctcacttaga gagaaaatcg cagagttaca gaaagacatt catgatggta ttgatgttgt
    12961 aggaaagaaa atgacactct gccagcttta cgcaaaacag aacgctcaaa gaccaaaggt
    13021 tagaaaaaac actgaaactg gacgcaaata tcttatggat attttgaaga aagacaagtt
    13081 aggtgtaaga agtattgaca gtattaagcc atcagacgct aaagaatggg ctattagaat
    13141 gagtgaaaat ggttatgctt atcaaaccat caataactac aaacgttctt taaaggcttc
    13201 attctatatt gctatacaag atgattgtgt tcggaagaat ccatttgact ttcaactgaa
    13261 agcagttctt gatgatgata ctgtccctaa gaccgtacta acagaagaac aggaagaaaa
    13321 actgttagcc tttgcaaaag ctgataaaac ctacagcaaa aattatgatg aaattctgat
    13381 actcttaaaa acaggtcttc gtatttcaga gtttggtggt ttgacacttc cagatttaga
    13441 ttttgagaat cgtcttgtca atatagacca tcagctattg agagatactg aaattgggta
    13501 ctacattgaa acaccaaaga ccaaaagtgg cgaacgtcaa gttcctatgg ttgaagaagc
    13561 ctatcaagca tttaagcgag tgttagcgaa tcgaaagaat gataagcgtg ttgagattga
    13621 tggatatagt gatttcctct ttcttaatag aaagaactat ccaaaagtgg caagtgatta
    13681 caacggcatg atgaaaggtc ttgttaagaa atacaataag tataacgagg ataaattgcc
    13741 acacatcact ccacatagtt tgcgacatac attctgtacc aactatgcaa atgcaggaat
    13801 gaatccaaag gcattacagt acattatggg acatgctaat atagccatga cgctgaacta
    13861 ttacgcacat gcaacattcg attctgcaat ggcagaaatg aaacgcttga ataaagagaa
    13921 gcaacaggag cgtcttgttg cttagtagta caaatgaatt tactacttat ttaccacttc
    13981 tgacagctaa gacatgagga aatatgcaaa gaaacgtgaa gtatcttcct acagtaaaaa
    14041 tactcgaaag cacatagaat aaggctttac gagcatttaa gaaaatataa aaagataatt
    14101 agaaatttat actttgttta agtataaaaa atgaaaaaat acgagcagaa aactgtttta
    14161 tctgctatac ttggttcgtt gcaagttccc gaaaggatcc gcaggacgga gatgccttgt
    14221 aaccgaattt aactaggggg aatcattata atggtagaaa gacacttatt tacatcagaa
    14281 tctgtttctg aaggacatcc agataaaatt gctgaccaaa tcagtgatgc aatcttggat
    14341 gcaattttaa aacaagatcc aacagcacga gtagcgtgtg aaacgtctgt aacaactggt
    14401 cttgttttag tatttggaga aatatctacg acggcatatg tagatattca aaaagtcgta
    14461 cgggaaacaa taaaagaaat tggttataca cgtgcaaaat tcggatttga tggagataca
    14521 gcagctgtat tggttgcgat tgatgaacaa tctcctgata ttgctcaagg agttgatgaa
    14581 gcacttgaga tccgggatga agataaaaaa gacgtattag atgagattgg tgctggtgac
    14641 caaggtttaa tgtttgggtt tgctgtagat gaaacaccag aattgatgcc tttaccaatc
    14701 gctttgagtc atcgtctggt acgacgcttg gcagatttgc gtaaatcaaa tgaattaacg
    14761 tatttacgtc cagatgcaaa atctcaagta acggttgaat atgatgatca aggacaaccg
    14821 gaacgcgtag atacaatcgt tatttcaaca cagcatgatg atgcagtaga taatgaaaca
    14881 attcgtcatg atgtcatcga aaaagtagtg aaggaagtta ttccagctga attattagat
    14941 gatcaaacga aatattatat caatccgact ggccgatttg tcattggtgg tcctcaaggg
    15001 gatgccggat taacaggaag aaaaatcatt gttgatacgt atggcggtta tgctcgtcat
    15061 ggtggcggtg ctttttctgg taaagatgcg acaaaagttg accgttctgc cagctatgct
    15121 gcacgttata ttgctaaaaa cattgttgca gcagggcttg ctcgcaaagc agaagtacag
    15181 ctagcttatg cgattggtgt tgctcaacct gtttcgatct caatcaatac tttcggtact
    15241 ggaacggttc cggaagaaga actgattgct gcagtgagag aaaacttcga tcttcggcca
    15301 gcaggaatca tcgagatgct tgatttgcgt cgtccgattt acaaacaaac agctgcttac
    15361 ggtcattttg gtcgtacaga tgtagatttg ccttgggaac atacggacaa agtagatgcg
    15421 ttgaaagcaa gtttagcaaa ataagttata ttcagctgga acgatcgcca agtggtggtt
    15481 gttccagctt tttttatggc agttaacctc ttgaaaaaga tagtaattat ttatctattt
    15541 ttagatcctg tcataatgaa agggaggaat aagatgaaaa aagaaacaaa tgttactttg
    15601 gtcacagtga gtattttcat tgcaacgttc atgacggcta ttgaaggtac aatcgtaaca
    15661 accgctatgc caacgattgt cggttcatta catggaatgg aaatcatgaa ctgggtattt
    15721 tcgatttatt tgctgacaaa cgctatgctt actccgattt acggaaaact tgcggataaa
    15781 gtgggacgga aaccaatctt tatttttggg acattattgt ttattatcgg ttcgttattt
    15841 tgcggtttat ctcaaagcat gattgggttg attgctgctc gtgcgattca agggatgggt
    15901 gctggggcaa tgatgccagt agctttgacg atcatcggcg atctttattc tattgaaaag
    15961 cgagcaaaag ttttaggttt gaatagttca gcctggggga ttgccagtgt ttttggaccg
    16021 cttgcgggag gattcatcgt tgaaacgatc agctggcact ggatcttttt tatcaatgtg
    16081 ccgatcggaa ttctattaat tattttgatt tggctatatt taaatgaacc aaaaatcata
    16141 catgagtcta aaccaatgga tatttttggt agttttagtt tgatggccat gcttgtctca
    16201 ttgctgttag ggttccaatt attaggagac gaaggaatga gtccgcttgt ttctgctttg
    16261 ctgctaggta gtatcgtaat gttaggtatt tttgtttttg ccgaaaaaag agctaaagat
    16321 cctgtcatca tgatgcattt attcaaaaat ccactatttg ttgtggtcaa cttggctgca
    16381 gcattggcta gtggtttttt gatgggaatc gatgtttata tccctatgtg gatgcaaggt
    16441 gtattagggc tgaatgcagc aattggtggg ctggtattag caccattatc actagtctgg
    16501 atggtcggtt ctttccttgc aagcaagtgg atgactcaaa tgaaaactca ttgggtcttg
    16561 agaattggac tactaatcgc agctattggg ggcgcttggt tgtatcttat gcctttcaga
    16621 agtaactatt tatggttttt tgctatatca acggtcatcg gtataggctt aggtgtgacc
    16681 atgactacct cgactgtcag tgcacaaaat agtgtatctc gtgaccagct tggtgtagca
    16741 acttctttta atacgttagt tcgaacaatt ggtcaaacag tcatggtttc tatttttggt
    16801 ttattgataa atggggtaac taaacgagaa cttgcagcag caaatttaac aaatgatgca
    16861 gatatcatga ataaactggt gaatccacaa acggctaaat atattgatgc ggatattttg
    16921 ttaccattaa gaaaaattct ttatgatggg ttacattccg tttatctagt tggcttgtta
    16981 ctcgtgatca ttgctttggt cttaacgctt ttcgttcatg aaaaaagtgg taaaataaaa
    17041 cagtagtttc ggttaagata tgtacgtagc cgaatcattc aaatttaaag ttattcaaaa
    17101 ataacttctt actaaggaag gcgaaaatat ggcatttatt caagcaaata tttattcgaa
    17161 tgtgttagaa atggaagtca atctaaatgt gatactaccg caaacaacaa aaaaggtgat
    17221 tggcaccagt tcagagcaag agacaacgga tatacctgtt ttatatttac ttcatggaat
    17281 gggtggcaat catagtgtat gggaaagacg tacgtcgatt gaacgttatg tagcaaacta
    17341 cggattagct gtcatcatgc catctactga tcttggctgg tacacagata cagtttatga
    17401 catgaagtat tggacattca ttgcagaaga gctacctgag atttgtcatg aattattccc
    17461 gcaattaaca agaaaaagag aaaaaacata tgccgctgga ttatcgatgg gcggatatgg
    17521 cgcgttaaaa ctaggccttg caaaatcaga aaatttcgca gcagtaatct ctctttcagg
    17581 cgctgtttct gtaggaaatc gaatggatga tcttttgatg gttcgtaaag catctttttg
    17641 ggaagggatc tttggaccat tggatcaaat cgaaggttca aaaaatgatc cgcaatactt
    17701 attgaaagaa ctagtaaaaa gcggaaaacc agttccaaga ttttatatgg cttgtgggga
    17761 atctgatttt ctttatcagg caaatcagga aatggtatct gctatgcagg aacaaggctt
    17821 ggcggtcacc tttgaacaag gacctggcga tcataactgg atcttctggg accaatggat
    17881 tcaacgtgca ttggcgtggc taatggaaga aaaataaaaa aagagtctta aaaagatagc
    17941 tcctatagag atcacaaaca tagtgatctc tataggagct tttttactgc tcgttttctc
    18001 ttcttttatt ttgttggcat aagccttcaa tataggtttg tgcactcgtt agaaagagtg
    18061 ctttttcatt caattctgca tgggactgca tactttcttt aaatccctct aattgatttt
    18121 caactacata attacgcata aatagaactg tttctttcaa aaattcattt ccgtccataa
    18181 ttttttgtcg aagctgctgt tcatgctgct gatccattaa ctgtccaatc aataaattgt
    18241 ggagagaggc aatggcctga tgactttggg tgactgaaaa tccttcacga acaagtaatt
    18301 ggatcatttg ctccaaatgt tctaatcgac tcggaaaagc gggcacagta ttgatttcta
    18361 attctgcccc acaagggaaa cgtgtataaa ggtcatagta attttccata tactgcagca
    18421 actgttcatt ccaaggcaaa gttggatctg gaagcgctaa ttcttcttcc attgtttcag
    18481 ccattttttg caagagctgt tgtttgtttt tgaaatacca atataaagca ggtgcttgaa
    18541 catgaattct gtttgcgatg tttcgcatgg aaagctgcga aagagcttgt gtttcagcca
    18601 ggatatcaaa ggcggcctga atgatgattg cttgagaaag ctttatttcc attttatcaa
    18661 cctcgtgtat tgcattatct ttttaaacat ggtaaattgt tagtcggtct aattttacag
    18721 tgttaaatta gtcctgtcaa tttaaacaaa ggggtgtaat caacgaatga aattaatctt
    18781 acgacatgcg aaaaaatata aagtagctgt ttttatttcc ttgctgtccg tagcagtcat
    18841 ggttgcagca gcattatggc aacctaagtt actacagcaa gtattggaag ctattattac
    18901 agaagataat gatgaaatga aaacaattgg tatttacctg atcagtctgg ctttgctagg
    18961 attagccgca ggtgtaacga acacgatttt ctctgcaaaa gtagctcaag gcgtaagtgc
    19021 agatatccga gaagaagcat ttcgaaagat ccagacattt tcatttggaa atatcgaaca
    19081 gttctctgct ggaaatcttg ttgttcgtct aacaaatgat atcacgcaaa tccaaaattt
    19141 agtgatgatt tctttgcaat cactttttcg aattccattc ttatttattg gtgccttcat
    19201 tttagctatg atcacgatgc cgcaattatg gtggatcatc gtagcgctta tcgttacggt
    19261 atttttgatt acggcacttt catttacaag gatgggcaag cacttcatga tcattcaaaa
    19321 actgattgat cgtgtgaata gcattgcaaa agaaaactta ctagggattc gtgtagtgaa
    19381 atcttttgta caagaagaaa accaattgaa gtcattcagc aaagtaagtg aggacttaac
    19441 aaaacacaac atcatagtcg gtacattatt ttctgtgatg atcccgtcct tcatgctggc
    19501 tgccaatttg gctgtggttg gggcgatctt ttttgtgagc gatcttgtta aagatgatcc
    19561 tacgttaatt ggtggaattg cttcattcat gaactacttg atgcagatta tgatggcaat
    19621 cattattggc ggaatgatga tgatgatgac ttcaagagca gccgtatcgc tgaagcggat
    19681 tgcggaaatt ttagatgctg aaccagatct tacttattta gacgttccag aacaagagtt
    19741 gacgggttct gtcacttttg accatgtttc ttttcgttat cctggtgagg atacagatac
    19801 gcttaaagat atcagctttt ctatcaaacc tggagaaatg gttggtatcg tcggggcgac
    19861 tggtgccggg aagtcaacac tagcacaatt gatccctcgt ctatttgatc cgacagaagg
    19921 caaagttgaa gtaggtggtg tagatcttcg tcaagtaaat gaaaagagtt taagacaaac
    19981 ggtttccttt gttttgcaaa aagcaatttt attctcagga acgattgctc aaaacttgcg
    20041 ccaagggaaa aagaatgcaa cagaaaaaga gatggaacat gcttcttcta ttgctcaagc
    20101 aaaagaattc atcgaaaagt tatctgatcg ttacgaagca ccaatagaag aacgtagcag
    20161 taacttttct ggtggtcaaa agcaacgttt atccattact cgtggcgtta tcggtaatcc
    20221 aaagatcttg atcctagatg acagtacgag tgcactggat gctcgctctg aaaagctggt
    20281 ccgagaagca ctcgatcgag atttgaaggg aacaacgacg attgtcatcg cacaaaaaat
    20341 tgcttctgtt gtcaaagcag accgcatctt agtattggat gaaggcagat tagtcggcga
    20401 aggaacccat gaggaattgg tagctggaaa ccgtgtctat caggaaatct ttgaaactca
    20461 aaaaggaacg gaggagtaag tatgactgat ctaataaaag caagtaaatt tttctatcac
    20521 tatttgaagc ggtacaaact ctcctttttc tttatcttta tcacagtgat cattgctacc
    20581 tatctacaag taaaggcacc tcaatacatc ggggaagctt ttcaagaatt agctaattac
    20641 gtaggaggct tgatgcaagg cgtagacgat aaaagcaaat ttgtttctgt aatatggaaa
    20701 ctcttgctgt tttatgtact agctagtgca gccaacttta tctatagtat tttgttcaca
    20761 caagtagtag ggaagtcaac gaaccgaatg cgtatcggtc tattcaacaa attggaaaaa
    20821 ttgacgatcc gtttctttga ttctcatcaa gacggtgaaa ttttaagtcg tgttaccagt
    20881 gacttagata atattcaaaa tagtttgaac caagctttgc ttcaagtcat cacgaatgct
    20941 gttttacttg tcgggatctt gatcatgatg ttccgccaaa atgtagagtt agcttgggct
    21001 acaattgctt ccactccagt agccgttttg atagctgtct tgattatccg caaagcacgg
    21061 aaatatgtgg atcttcagca agatgaagtg gggaaactaa atggttatat ggatgaaaaa
    21121 atcagcggac aacgtgtcat catcacaaat ggcttacaag aagaaacgat tgaaggattc
    21181 ttagagcata atcaaagtgt tcgcgaagca accttcaaag gacaagctta ttctggtcta
    21241 ctatttccga tgatgcaagg aatgtcactg gtcaatacag cgatagttat ctttttcggc
    21301 ggctggttag cattaaatgg tgatttggaa cgttcggtgg cattaggctt agttgtgaca
    21361 ttcgtccagt attcacaaca atattaccaa ccactgatgc agatttcatc tggatacagc
    21421 atgatccaat tagcgattac aggggcaaga cgattgaatg aaatatttga tgaaaaagat
    21481 gaagtcaaac cagaaaacgg taaagcattt gatggtgttg aaaaaggtct tgcgttgcag
    21541 cacgtagatt ttggttattc tccagaaaaa ctagtcttga aagatgtctc gatcaatgtg
    21601 gacaaaggag aaatggttgc tcttgttggt ccaacaggat cggggaaaac gacgatcatg
    21661 aatctgctaa accgttttta cgatgtcaat gatggttcag tagtcatcga tggaatagat
    21721 atccgagatt atgatcttga tgcattacgt agacatgtag gaatcgtttt gcaagaatct
    21781 gtattgttct ccggaacgat caaagacaat atcacattcg gcaaaccgga cgcttcagat
    21841 gaagaagtca tcaatgcagc aaaacaagcg aatattcatg acttcatcat gacgttagaa
    21901 aaaggttatg atacagagat atccgaagaa aataacttat tcagtacagg tcaaaagcag
    21961 ttgatcagta ttgctcgaac gatcatcaca aatccatctt tattgatttt ggatgaagca
    22021 acaagtaatg tagacacggt aacagaagca aggatccaaa aagcaatgga tgaagcaatc
    22081 aaaggaagaa ccagctttgt gattgctcac cggctgaaaa caatcttgaa tgcagataga
    22141 atcgttgtct tgcgtgatgg ggaagtcatt gaagaaggca gtcatcatga gttattagca
    22201 gaaaatggat tttatgcgga actttatcat aatcaatttg tatttgaaag ttaaattaaa
    22261 agaacctcgt tataacgggg ttctttttat atattttatg ttgtttgttt ttataagggg
    22321 cagaaaaggg gcaatttaaa tttctatttt tcctagtttt tctactagtt gattttgcat
    22381 atttttagtt gtatgagtat aaatctttaa tgttgttttt gaatcttcat gtcctacacg
    22441 atccataatg gcttttaatg ggattcctaa ttctgtaagt agagaaatgt gggaatgcct
    22501 taacatgtga gaagaaactt ttttatctag gtttaattct ttggatactg ctcttaaaga
    22561 ttgattatat gcttgaatag atatcgggtt accattttta gagatgaaaa tgtatttatc
    22621 tttattattc tta
//
LOCUS       DADGKS010000044        22367 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.044, whole genome shotgun sequence.
ACCESSION   DADGKS010000044 DADGKS010000000
VERSION     DADGKS010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22367
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.044"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(143..457)
                     /locus_tag="JXV47_001792"
     CDS             complement(143..457)
                     /locus_tag="JXV47_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487834.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
     gene            743..982
                     /locus_tag="JXV47_001793"
     CDS             743..982
                     /locus_tag="JXV47_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487835.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(1344..1604)
                     /locus_tag="JXV47_001794"
     CDS             complement(1344..1604)
                     /locus_tag="JXV47_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487836.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVIGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1789..2286)
                     /locus_tag="JXV47_001795"
     CDS             complement(1789..2286)
                     /locus_tag="JXV47_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HAX1487837.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(2416..3126)
                     /gene="budA"
                     /locus_tag="JXV47_001796"
     CDS             complement(2416..3126)
                     /gene="budA"
                     /locus_tag="JXV47_001796"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HAX1487838.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(3139..4803)
                     /gene="alsS"
                     /locus_tag="JXV47_001797"
     CDS             complement(3139..4803)
                     /gene="alsS"
                     /locus_tag="JXV47_001797"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HAX1487839.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(5008..5670)
                     /locus_tag="JXV47_001798"
     CDS             complement(5008..5670)
                     /locus_tag="JXV47_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAX1487840.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            complement(5680..6495)
                     /locus_tag="JXV47_001799"
     CDS             complement(5680..6495)
                     /locus_tag="JXV47_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAX1487841.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(6757..7200)
                     /locus_tag="JXV47_001800"
     CDS             complement(6757..7200)
                     /locus_tag="JXV47_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HAX1487842.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(7334..7672)
                     /locus_tag="JXV47_001801"
     CDS             complement(7334..7672)
                     /locus_tag="JXV47_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAX1487843.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(7660..8037)
                     /locus_tag="JXV47_001802"
     CDS             complement(7660..8037)
                     /locus_tag="JXV47_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAX1487844.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            8261..9454
                     /locus_tag="JXV47_001803"
     CDS             8261..9454
                     /locus_tag="JXV47_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAX1487845.1"
                     /translation="MTTYQRKLLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(9620..10042)
                     /locus_tag="JXV47_001804"
     CDS             complement(9620..10042)
                     /locus_tag="JXV47_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAX1487846.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            10632..11087
                     /locus_tag="JXV47_001805"
     CDS             10632..11087
                     /locus_tag="JXV47_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487847.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQQAAAEQASQQAQAAAP
                     EQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSKCYGN"
     gene            complement(11249..12421)
                     /locus_tag="JXV47_001806"
     CDS             complement(11249..12421)
                     /locus_tag="JXV47_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAX1487848.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(12627..14056)
                     /locus_tag="JXV47_001807"
                     /pseudo
     CDS             complement(12627..14056)
                     /locus_tag="JXV47_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306286.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
     gene            complement(14053..15555)
                     /locus_tag="JXV47_001808"
                     /pseudo
     CDS             complement(14053..15555)
                     /locus_tag="JXV47_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345213.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
     gene            complement(15552..17879)
                     /locus_tag="JXV47_001809"
     CDS             complement(15552..17879)
                     /locus_tag="JXV47_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAX1487849.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSATETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            complement(18722..19015)
                     /locus_tag="JXV47_001810"
     CDS             complement(18722..19015)
                     /locus_tag="JXV47_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HAX1487850.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(19418..20596)
                     /locus_tag="JXV47_001811"
     CDS             complement(19418..20596)
                     /locus_tag="JXV47_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAX1487851.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            complement(20700..21014)
                     /locus_tag="JXV47_001812"
     CDS             complement(20700..21014)
                     /locus_tag="JXV47_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1487852.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            21121..21336
                     /locus_tag="JXV47_001813"
     CDS             21121..21336
                     /locus_tag="JXV47_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487853.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            complement(21636..21878)
                     /locus_tag="JXV47_001814"
     CDS             complement(21636..21878)
                     /locus_tag="JXV47_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1487854.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(21865..22293)
                     /locus_tag="JXV47_001815"
     CDS             complement(21865..22293)
                     /locus_tag="JXV47_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAX1487855.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFFI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
BASE COUNT         6629 a         4373 c         3756 g         7609 t
ORIGIN      
        1 taaactctag agaaattaat tcatcctaac ataaaataat tgttcactca aaagtttttc
       61 tagaacaatt aaaacagcag gcttcacatt cgctatacat ttgtaagaag taataattcc
      121 tgtactaaaa ggcataattg ctttaattat tttttgactt ctcttcaaac acaagaagta
      181 gttgtgtaat aattgcagaa ataaggattc caataataga tataaaattt gacatggaaa
      241 cgtctataac attaaaagaa taaagtgttg aagaaagtaa actgattgaa ataacccctc
      301 cgtaaaaaat agtctgtgaa tatacccact ttttttcaga agacgtactt cgtttggttc
      361 taaaacctat ccctgcattt ctactcttat caaaaaacca aatatttaga agtaataata
      421 ttgctattat taagataaaa ttactgtaaa aatccaaaag ctatcctcct agcaactatt
      481 taaataccca aaaaaattac ctctagataa tatcatacct acgttttcac ttataaattt
      541 tttcataaaa aaagcgttta gaggcataat cgttaataca gatggtaacc aatgtatctg
      601 gtttgaactg ggatatcacc ctctccatat atgtattact aagactaata gatactataa
      661 aagacttgat agttttgcat tgattttgcc taatactgag cataggtgta tgctaaacga
      721 tactataagg agtgtgtaca taatgaaaag aattctgttt atcagtttat caaatttatt
      781 gttacttact gcttgtggga cttctgcatc aaagaacata ccttcagata cgcaaatttc
      841 gaatagtatc gattcaacaa tttctacaaa tgagaaaaat tctccggtag aaacttccga
      901 tataaaagtt tctacctctg caaaaaacag ggtaaagaaa ctgtcagcac gtctccttta
      961 tttcaaacaa actctgaatt agcttcttca tcttcttcag caaataatga tgatagtttc
     1021 gcgtttactc ctaactaaat gcaaccttta caaatgcttt acgataacaa gcctgagcta
     1081 aatgatcctg atatcagttt tgcatttttt gaaatgattg gatcggatga tctttttaaa
     1141 actactagtt tgtctatccg aaaataggac agttctggca gtataggttt ttatcgagtt
     1201 tctccaccag gcctcgttac agagacagat tctctaggcg aaccttttga ataaatcaaa
     1261 aatcatgaac aatcactgcc aactaaataa agtgccttca aaagcttggt cttctcgctt
     1321 ttgaaggcac tttatttaaa tctttatgaa actaaagtat gttcatattt gttgctatag
     1381 ttatatagat attctgttgt ttccaactca taaacgtgag tatattttgc cactactttt
     1441 ccgcattttt ctaatatttc attgcgatcg acgtcatgat attcgtctac gcagatcaca
     1501 acacaatttt ctaatttact gattacttct ccaatcactt tttgtttcaa gccaataggt
     1561 tggcaaatat atttttttcc taaaatgata gtttcgttat tcatatttca tccatcctta
     1621 atgttttttc attatttaaa atgataataa cattaaaata tgattatgaa aatcaataac
     1681 acttgtgatt ttataaaaaa ataaaaaaac cgaaaaacag aaatgcccac tgtctttccg
     1741 gctcttttta ttcttgattt ctcttctttt ttgtttcaat agacgatttt agttattaat
     1801 aaatgaaaaa gcatttatat taaaatttgc taataaaaga tctacatatt tttctagaaa
     1861 tgcttgatcg atttcatcat accctttcgt tactccgcaa tcgatatcta aaacaccgat
     1921 taaattacct tcttttacca ttggcactac gatttctgat tgtgcggctg aatcgcagga
     1981 aatgtaattt gcatgggttt tgacatcatc aacgatcaat gtttcttgtt tttcagctga
     2041 ttctccacaa actccttttc ccatcttgat acgtgtgcaa gaaactcgcc cttggaacgg
     2101 tcctaaaatc aattcattac catcgaataa ataatatcct gcaaagacag tctcaggcaa
     2161 agtctcattc aacaatgcag atgaatttgc taaatttgct aaccagttat cttctgcttc
     2221 taataatcct tgttgctgta ataataaaat ttcgtatgca tcttttttct gtttttctgt
     2281 ccacatgata aaaaccgctc ctttttgatc tatggagaag attatagctc agtttttttg
     2341 taaacgctag gttttctcct caaaaaaacg agatacgtca ggttaatcac cttgaacgca
     2401 tctcgctgtc tttttctatt ctgcttgttg gatttctgct gctaaatcag cataatcaat
     2461 cgtttcgtga acaaaagtcg gatcatcaac tggaaaatgc tgtacaaggg acgagatgcg
     2521 gctaatctca acttttcctt cagccacttc aaaatccatt acatgtccgc caaatgtatg
     2581 tgtatcatcg ataaaatgca ggtgaaatcc cgctgcagca actccttgga ataattcagg
     2641 cgtaaagaac ccgactaatg ttccttggac attgctttgt tggaattctg gttgagactc
     2701 tgaaattttt gctagtcttc tgtaaggttt ttcttgcttc ggcatgatac ggatgtgcat
     2761 atttttgaat aatccagtta tcttcactgc caaaaatagg ttttccccgg cttctcttac
     2821 taatatgtct tttttcaatt gttctccatc tgcagttttt gagacagaaa aactagtatc
     2881 tggcgtaaaa tctgtaattg ctgcataggg ggtaagttca cttccatcta attgggcaac
     2941 tgagccatct gatcttcctt gataagctac gccatctaaa aagatgactt caccatcaag
     3001 cccatgcaat gttcccaatc ccagagttcc tttttctaat atatgagcaa tcgtttctgt
     3061 tccatccatc aagccagcca tcaaagctcc taatgtcccg tgctggtata agattttttc
     3121 agtcatgtcg acacttcctt aatagaattg atctggtaag attgtttctc ccaatttctc
     3181 attatcacgg taatcaatcg gaatatcaat aattacgggt ccttctgtcg caaatccttc
     3241 ttctaaagct ttttctaatt cctctacact tgtagctcgg attcctttag cgccaaaagc
     3301 ttctgcatat ttcacaaaat caactggacc aaagtctaca cctgacgccc gctgatattt
     3361 cattttttct tggaactcta ccatattgta gtgtccatca ttccaaatca aatgaacgat
     3421 attcaatttt ttacgtaccg ccgtttctaa atcctgggca gagaataaaa atcccccatc
     3481 gccggaaact gatacgattt gtgtatttgg acgcaccaat gcagcagaaa tcgcccatgg
     3541 caatgcaaca ccaagcgttt gcataccatt actgaataac aaatgacgag gttcataact
     3601 tctaaagtgg cgtgccatcc aaatataatg actacctaca tctacggtaa cagtcatatc
     3661 atctgttact tttgactgaa gcgtgttaat aacttctaaa ggatgcaaga tacctgcttc
     3721 tccttttgat tgaacaatgt cccgctccgt taattctgct tgaagagatg ctaaatattc
     3781 ttttgcatct tctgacactt gttgaggctc taatgaacct gtcaataaat caagagtggc
     3841 tgagatatca ccgatcaatt ctctttcagg ctgcataaaa ggatcgattt cagctggcgc
     3901 ttcatcgatc acaatgatcc gcgcatcttt ttccgcattc cagtttcttg cttcatattc
     3961 gattggatca tagccaatag caataactag atcacttcgt ttcaaaagca tatctcctgg
     4021 ttggtttcta aataaaccca cacgaccaaa gaaatgcgct tctaattcac gtgagatcac
     4081 tccagctgct tggaatgtct ctacaacagg caatgctgtc tttccaacta attgcctgat
     4141 ggctaacgtt tctttttcac ttgatcctcg catacctact aatagtaccg gtagttttgc
     4201 ttctctaatg cgttcagcta ggtaacggat atcatctgca gaagcagaac ctaatttagg
     4261 atcgctcaat ggcttgatga cattcccttg gacaggtgca tccactacat cttgcgggat
     4321 actgataaag ctcgcgcctt tttttgaact cttagccata cgataagcat tggcaatcac
     4381 ttctgaaatt gtttctggat cttggatttc tgcactgtat tttgtgattg gctggaacag
     4441 tgctgcatta tccatgcttt gatgggtcaa cttcaataga tcgcttcgtt ttacttgtcc
     4501 ggcaattgct aaaactgggt caccttctgc tgtcgctgtt accaaacctg tagctaagtt
     4561 actagcacca ggaccacttg ttgcgataac tactcctggc tctcctgtaa tacgtccgat
     4621 tgcttgtgcc ataaatgcag cattttgttc gtgacgagtc acgattaatt caggaccttg
     4681 atcctctaat tcattaaata caccatcgat ttttgcacct ggtataccga atacataatc
     4741 aacatgatga ttaatcaaac tttctactac agatttcgaa ccttgtttca ttttttcgtc
     4801 cattgaacat cgtccttttt atgctttatt tttaattatt agttagaaat aatcacaaat
     4861 aattgataca gtttctaaac ctgtttcatt caaaagtata gcacgtttta tttcatttgt
     4921 ttagccatat gtttcaaaaa atgaaaaaga atgacagttt ttacataaaa actgtcattc
     4981 ttaattgaaa gtttcaattt ataaagtcta cagatccata gttctcatca atttacgatt
     5041 gttgaagtaa atcaaaccaa atacgataga aggacctagt agaatacacc attggggctt
     5101 tacgaaaaag aagagaaaca aacttgtcaa tagtaaaaaa tctagtaaac tcacatacca
     5161 ttttttcaac gtatagtaga acgctatccg tagaacttga tttggtttcg acgctggatt
     5221 tctcacctga aaataccagt agttgatgct aaaggaaact gataaacaag caagtaaaac
     5281 aaacaacgga atcaaccatt ttccataaga aaaacgtata aaaaagaaac aatcaaaaat
     5341 cattatcaca ctaactatcc aagcaaatag ccaataaaaa aatcccttta gccaaaattg
     5401 gcgaaacgtc tttatgaaca aacgtactgg tgaaaaactt ttttcttttg ctaattcttc
     5461 tgtcatacct atcatcacga tgcaacctgg accaataaaa agtaaagaaa aaataaagga
     5521 aaagacattc cttccatcta tcgacaaaag gaacgcagct gctatataca agatattgac
     5581 acaccaaaaa caaaggctac ttgccaatga ttgatacaac caataaaaga attccatata
     5641 aacatttttg tcaaaacgct gctctttcat aatcacctcc tattccttca ttcctgatga
     5701 agcgatccct tctacaaaat atttttgcat cgctaaaaat ataaaagcaa caggaagaac
     5761 agaaacaact gaggcagcca tgattaatgc gtactctgca tcaaatagcc caataaacat
     5821 tttcaaccct aactggattg ttttattttc cgtagaagac aaataaatga atggccccat
     5881 ataatcgttc catgtattaa cgaatgtgat gatcgtcaaa ctggcaatcg ccggttttgt
     5941 aagaggtaaa atgatcttgc gatagattcc ccactctgat aagccatcga tccgcgcact
     6001 ctcacataaa gaatctggga tactactgta gtattgcttc aacaagaaca caccaaaagc
     6061 attgaacgct tgtaatagca ccaacgacca caacgtatat gttaaaccca cttttctcat
     6121 cataatgaac tgcgggatca tataagactg ccaagggaca gcaatcgtgc cgatatatgc
     6181 taaaaataaa atatcgcgcc ctttaaaatt tagtttagaa aacccgtaag cagcaaaact
     6241 agaagtaaac aactgaatca acgtgatcac aacgcttaaa aaagctgtat tcttaaaaaa
     6301 tgtcactaaa ggaatacgag accaaataac cagataattc tctaaatgcc aagttttagg
     6361 gatccattga atcggaatcg tgaacacttc attatttgct ttgaatgaag cagaaaccat
     6421 ccataaaaaa ggaatgatcg tcaataaagc taatacaatc agcagaatca tacccaacca
     6481 ttgaataaag ggcatgtttt ttgaacgaat ttttgctttt tttctttcat ttcgaacacc
     6541 tccaaagtta taatcttcat ttctttgtaa tgattacaat ccagaacaac ggttattata
     6601 gctgattcat ttccgttctt cttatgtttg taagcgctta tttaacaagt tatgtaaatc
     6661 tctttatttt ttttgattta aaaatgaaaa aatacaaaag caagactgtc atacgtctcg
     6721 cttttgtatt gaaatttctt cgattagaga tacttattac tgttcaaaag cttctttgaa
     6781 acggtgaatc aattcattga ctacaggtga taaaatccga ttctttttcc agactagcat
     6841 gcagttcgtt tcaatcattg ggtcaagcgg aacgaatgtc actcgctttg aaagatgact
     6901 tacagcacct tctatgacta aagcagcacc tacctgattc tcaattagcg caaatacatt
     6961 gaaaatcaaa ttgtacgttc ctgtgatcag caactgctcc ttttttatgc ctaaccagtc
     7021 agcaaacatt cgctgtattt ctggacgctt tgagatcaaa agaggtacat tcgcaaagtc
     7081 ttcttttgtt atcacgtctt tttttgctaa aacagaattt tctaaaatga gcaatcccca
     7141 tttttccttt cttggtaaca aaatcgtttc gtatttctct gtatctactg gatctagcaa
     7201 aatcgctaaa tctaacaggc ttttttctag tcactccgtg atatcatcac ttgttccgct
     7261 gtggatatga aattgaacgc tgggataatc acggatcaac ttttctagta atagtgccaa
     7321 tgtattcgaa ttatcagctt ccacacagcc gatcgtaaat cggccgctga ataattgttt
     7381 ttttctgttc tcgaattctt gagtggtttg attcgttaaa tctaaaattt cttctgctcg
     7441 gcttttttag aaaataacct gcttctgtca agatcatttt gcggttttcg cgtacaaaca
     7501 gttctgttcc tagttcctct tctaactcct tcagttgtcg gcttaaggtt ggttgtgtaa
     7561 gatgtagaac ttctgcggct tgagagattg ttccttcttc tgcaattgtc caaaaatatt
     7621 ttagtaagcg taactccata gcgatgctcc ttgatttttt tacttgatac attccatttt
     7681 atttctagat aacacacgat catatttctt gatttttcct tgtaaacgtt ccaaacattc
     7741 ttgcatttca gcaatttttt tcgtcaaaag ttcactttct tcaatcaaaa gcttacgccg
     7801 ctcaaataca gttgcttctc cttcgctaga taggcgaata tattcaatca aagactcgat
     7861 cgataatccg gcatttcgca tacagatcgt aaagtcgacc cattttaggt cttcttctgt
     7921 ataatcacgg attccgcctt ttgtccgatt aactggtgga atcaacccga ttcgttcata
     7981 atagcgcaat gtatcggccg aaatgccctt ttcttcactg acttgtttga tattcatctg
     8041 atcactcttt ctcttaattt cttgccactt tacttatgta ttttatttat tctacaactt
     8101 taagtgtact ccaagtcaat actcatttct attaaaacta agctggatta tctatatcgg
     8161 ttgtttgtgt attatttcaa ataaaaaagt cttgtttttt tattcttttt tggatatact
     8221 tttaacaatt tagggaaatt ttaggaaaag gggtataaaa atgacaacgt atcagcgaaa
     8281 gttattatta tcgacatcgg cgggaattgc tttagagaat atggatatta tgtttttagc
     8341 tttttcatta tcttcaatga ttacttcttt tcatattagt ggtacgcaag cgggtttcat
     8401 ttcaacgatc actaatttgg ggatgctcat tggaggtatt ttttttggca tcatagctga
     8461 taaatatgga cgtgtgaaag tattttctca aacggtcctt ctgttttcga ttgcttcttt
     8521 attgatgtat tttgcttcaa acatctactt ggtttatctc tttcgcttta tcgcaggtgt
     8581 aggagcggga ggagaatacg gggcgtgtat gtccttgatt tccgaaagtt tttcaaaaaa
     8641 acaaattgga cgagcttctt cggttgctgg tattggtgcg caggtcggtg cggctttggc
     8701 tgcgatttta gctgctgtga tcattccaac gtttggttgg aagatgttgt atgtcgtagg
     8761 tgtactgccg gtgttgatgg tcttgttcat tcgtcgcggc ttgactgaac caaaggaatt
     8821 caaatctgta caatctgccg aaaagaaaac caaacttagc agactgtttg aatcaaaaca
     8881 tcttgcttgg caaacatgtg gccttagtat catggtaact gtccaaattg ccggctattt
     8941 tgggttaatg aattggctgc cttcaattat gcaaaatcga ttagggcttt cggtttctgg
     9001 gtcttcattg tggatggtca gtactatttt aggcatgtct ttggggatga tgacttttgg
     9061 cataatcatg gataaattgg ggcctaaact agccttttct ttgtttttaa tttgttcatc
     9121 cttatctgtc tatctacttg tgttagccca tagccagtgg agtttggtag cagccgctgt
     9181 gatagtcggc tactttatca atggcatgta tggtggatat ggcgcagtga ttagtagttt
     9241 gtatccaaca gaaatccgcg cgacggcgaa taatttcatt atgaaccttg gacgagctgt
     9301 tggtggtttt tcttctatcg tcatcggttt cttgatggat cattatagtt taactgccgt
     9361 aatcttgttt ttgagcggta tttacctagt cagtctgctg gtcttgacaa ctcttactgg
     9421 tgttacagca ttaagggaaa gcttgcagca ttgatagttg agtctgtaaa tgacaagaaa
     9481 gaggtgtggc aaaagcttgc atctgcggta ataagaccag ccaaatcaaa aacatgagac
     9541 actgtttccg tttggctggt cgtattactt gatgcagggc agctttttca actgctaatt
     9601 tccttctatc tggcggctac tattctttga cgtccgtcat ttcaaagtac tttactaata
     9661 acttagcata acgaaaaact gtggatacac tcgtatattg agcgtctgca taatcttcca
     9721 aatttttctc aggatgttga tacatgaatt caatcaaatg ataattatat gattttctgt
     9781 agaaatgaag ataaataatg tagattggga agttctcctg cttttccata gaaaagcgcc
     9841 gattattctc attcttcaaa atgaccttat caggatattt ttggaacaat tcttctaaat
     9901 ctgttagata attcaagata gacttacttg ataccttcaa ttcgttttgt agttcttcta
     9961 ttgaacacca acgttctgtt tcaagcagta aatgaatcat tttaattttc ttttgagaaa
    10021 cttttgttaa aaaagtctgc atattttctc ctcctgtatc tactttacta tactacatac
    10081 aagaaaaaaa acggatacaa atatcatatt gtcacaccgt caatagtgca taaacctgtt
    10141 attatttctc tttttttcct aagtattcta ttgatatgaa tcatttaatc gtttattata
    10201 taaatgtcaa taatctaata ataaaataac gtacatattt tattattgca tacttaataa
    10261 cagaactata gcaaaaaatc ccgtgtatca aaacgggatt agattaagtt tcctcaatca
    10321 ctattcataa cacaattatt ataacaagta agtaaacaat tgaaaaggac atttattgaa
    10381 aacggttgtt ttttacttaa ggaggaaatt tagtgaaaaa attagttgca ttgtttttgg
    10441 tcgcaggaag tttgttgagt gggtgtggtg ctactacgtc tactactcaa agcacaagtt
    10501 cagctcaggc ttccagcagc agtaccacga tctccgaaag tacggcagat tcatcgaaag
    10561 aacaagaaca aattgaaaag aaaaaagaag aagagaaaca aaaagcggaa aaagctgcac
    10621 tagaaaaaaa agtgacagaa gcggaatctg ctttgtcaca agctgaagca aatcctacaa
    10681 aagaaaacta tgcaactgct tcagcagcta tccaagcgct acctgaaaac aaacaagagt
    10741 tgacaagccg tcttgctgca attgattcca caatcaaagc aaaagaagca gaagaagaac
    10801 ggaaaaagca agaagaaatt gcacgacaac aagcagaaca agcgcaacaa gaagcaatcg
    10861 cacagcaaca agcagaacag gcgcgacagc aagcagcagc tgaacaggcc tctcagcagg
    10921 cacaagccgc agctcctgag caaaataatg aacaaactgt ctatgtcaca ccgaccggtt
    10981 caaaatacca tacacataaa tgtggaaatg gtacgtatac ccctgccact ttaagcgaag
    11041 ctcaagctcg tggtttaacc ccttgctcca aatgttatgg aaactaattc aaaagttata
    11101 ctataataat aaaattcttc tgaaacataa aaaaatagaa gctggcgttc cagatagtaa
    11161 accaaaaata gcagtttaca cgtccatttc gtcagcttct ctcttttttc atttagtctg
    11221 ttccctctgc ttttttggac atcttcattc attctttctc aatcaaatag tacacctctt
    11281 tttcttttcg cagtttatat cttccttttt tcaatttcat tgaaaactgt ttcgaatgtt
    11341 tatgttttac atggatttta agcaggagct cctcatgttg caagcgatag ttcctgcctt
    11401 ttaaatcaga aaatctcact agtccgtatt catcagaagc tttcacaaat ggaacttttt
    11461 ctctagtaat atagtgtttg ccgttgagcg tttttacaga aaagaccatt ccttcgattg
    11521 gtcgtccgtt tgtgttcttt acataaaaag ataaaggata gtttcgctta gcgatggcca
    11581 aagaatctaa ataagcgatg agtagccaaa ctaagccgat tgatccaagt agtataccga
    11641 taaaccaaat aaaaaatttc cattttttcc attgatcaat tccttggatc gctttttttg
    11701 cctcttttgc ttgataagga atacgatgcc ccgtcacaag cagtcgatgt gtattgacca
    11761 tataaggagt acaggtaagc aaagtcacga gatctctgcc tttttggata cccaaagaat
    11821 ctacttcatc aggtaagacc acttggattt tttctacttg atacgccaat gtctttccat
    11881 tgatctggat gaaaaactgg tctccttttt tcaacttagg caaatctgta aataattttg
    11941 cttctgggag tccacgatgc ccagaaagaa cggcatgggt gtttttcccg ccagtcggat
    12001 aagaactttc ttccaataat gacgttcctt tttgcaaaaa tatttccgtt gtctgatcga
    12061 atataggtaa gctgacattg atttttggga tttcgatgac tccaagcata tgttccataa
    12121 aaaaggcatt actaggtaaa tcttttaatg cttttgcatc aactgcttgg ttgaaactgc
    12181 ctatccctgg tgatacgttt tgctctgcca actgttggtt tttctttgtc attttttcct
    12241 gctgtttttt tatttcctct gaattcttat tcgatgcttg cttttgataa tggatgatca
    12301 tttgctgggc aagaaaatca ttcagtgaat cttctacaaa aggataagaa aagatcccga
    12361 tcccaacgac taaaatgatt gccatgaaga tgtccagtat tcttattctg cttttattca
    12421 tcatgtccac ctattttcta atatgtatat gaagaggttg tgaaatcagc gccttgacct
    12481 gagtattcgc tcaacaaacg gcaaaatagt tcctcctatt ttgccgtttg ttgagcgaat
    12541 accaagagac cgaccacttg tcacaacctt tctccccatt tgaatcacta tcgtttattt
    12601 atcgtatgat ttttgtttcc aatagtttaa gcttctgttt cttgatggcg ttttttgaag
    12661 tagatcactg ctcctccaac taaagcagta cctaccaaga tgaatacgat gatccccata
    12721 ccaccagttg aaggcaagat tcctttaggt tggttatcga tcgttgtttc atcagaagtt
    12781 gttggatcat catctactgt aaattcagtg tacgcagctt cattcttagg taatgcgtag
    12841 ccttctggtg cttttgtttc ttgaaggcag tatgcccctt gtttcagccc ttcgattgaa
    12901 aatttccctt ctgaatcaga aatcaatttc acttcttccc agtcagaacc tgtgacttca
    12961 tctgaccaag catatgggta ttctcctgag gcaagatttg ctattttttt cattaattta
    13021 acagttggat cttttgctct tagaatagaa aattctgcat cggctaattt ttcttgcgtg
    13081 ttcacatctt gtttgatgaa gtggaaatca ccgtagtttt ggacattttc tacagtaatc
    13141 gtgttatccg tagttgtatt ttcccgattg actacaccgt ttggattccc aagattggct
    13201 tcatctgcgc catggatgat accggttgtt tgttgcaatt ttccgttttt tactataaaa
    13261 gtagtttctt tttgtggatt ggttaattga taaccatctg gtgcttttgt ttcaactaaa
    13321 gtataattgc cgtctattaa tccattgaca ctgatggatc cttcagtatc agttgtgaat
    13381 gtcaacgctg actcagcagg atcatagaga gcgacaccag tgttttcatc aaaaccggtc
    13441 acgaattgat tctctgaatt tttgatctgg aattgcgccc ctgctaactt atctacccct
    13501 gaaaagttcc cagctttctg gattttgata ttgctttctt tgatgacatt tttagcatat
    13561 aggtgaatcg tgtctaaagg tttgtcaggg tctgatgaat tcgggttata aaagggtaag
    13621 cttaacacga tatttggcga cgtttcgaca ccgggctttg gtgtttctac aaagacgtat
    13681 acagcatctt tcccatcaga tttacctgga agagtcaggt tagctaatcc ttcaccagaa
    13741 gtcgttacac ttgcgaaggg tgtagcgtct gctggaactg ctgtgtcttt acttggatag
    13801 tacgtagcag tgatgtcata tacgttgaat tcaacgccgt tcaacggttc gctattcgga
    13861 aatgtcaatt ccgttccgtt gtttatttga ttttctggtg ctgaagtgaa tttcaattta
    13921 tgcaaattaa ccgtaacatt ttctggtgta ggtgatacgg cctagaaacc tctgcagttc
    13981 ctaggccgag aacgaaagga agcagcatga tagcagttcc taaaaacgtc catatttttg
    14041 ttttgatgtt tttcatttta tttccctcct attgtttcct ttttgttgtt ttttataaaa
    14101 ccaagctgtc cctgttgaaa ggactagcaa caaccctaaa attgagaaac ctccaagcat
    14161 ctcttcgctt gtttttggaa agcttcctcc atttttttca tttgatggac catttgtctg
    14221 catctgaact ggcgtttttc cattattcgt cggatttgct tttggttcgt tgatgatttc
    14281 caatggtata ggatgaagcg gatcataact gcctttttca acttcaaaga gaatggttga
    14341 ttgactcaat atatatcctt taggcggttt aatctccact agttcgtaac ttccaaaaga
    14401 caatccatgg acagaaaatg ttccatcttt actggaagta aaaatcgttg ctcttgaatc
    14461 atctttggct acccaatgat ttatcccgtt ttcttgcgct aagtattggt catttttttt
    14521 gactagaaat tgagcatctg ctagtttttg tttcgtttgc cgatccactt tgacaaattg
    14581 tttgcctcct gtttggatgg caagatgtgt ttctactgtt tgattgtcag tcgtcaaacg
    14641 tacatcgtta tcaaatgtcg ttttttcact gttttctttc aatgtcattt ggtaacggat
    14701 cgttaatttt ttcccagcaa acgaactaag atcttttcca gaatctgata agacaaaacc
    14761 atgttttgtt ttttgtgtgt gaaatgtatg aatcttgtct ccaccaatca aaaaatcgat
    14821 cgtttctggt tctagccata actgaggatc agctgtatct ttgatcgtat aggttcctat
    14881 ctcgttgatg ttctcaggaa ttgttacggt gatgagataa ggaactttat ccccatctgc
    14941 aaaatctgtc tgcttattct ctactgtttt tgttaatgtg agtgcagcag gtattttttg
    15001 ttcgctcttt ggatacaagt ggatggtcgt caatttatga ttagatgaat ctgtcacagg
    15061 aagcacaacg acaaatggtg ctgatttttc ttttacttaa tctgaagtct ttatttccgc
    15121 aaatcggtaa acagcgtcac gaccttgctc atctttgtcc gatgcactaa aagaagcaat
    15181 gccctcttcc tcgtctactg tttttgtcac attttctgcc agtatttttt cactatcact
    15241 tttttgtgct agttttcttt gtgcgtcttc cacactactt ccttctgacc gcagcttgta
    15301 aaattcatcc gagacatcat atatagcgaa agtaacgccg ttcaaccctt ttactccttg
    15361 aaagttatcc gggatattta ttccgtcgtt ttgactgata cttggcatct tatcgctttc
    15421 gaacattcga ttatgcaaag taaatgtaat aggtgattct ctagctgaca cagtcggaga
    15481 acctataaaa aagaccagta ggataaaaaa gagaacagca aatatatcca cacgtacatt
    15541 ttttgttttt ttcatcgctg ttcacctgct tttttcttac gatggataaa ataaaagaag
    15601 ccagaaaaaa taaagatcag tcctaaaaag acaaagggca gtagacctat cccacctgtc
    15661 gaaggaagca agagagtcgg attgatcgtc aacttagcgg tatctgttgc gataatcgta
    15721 taattattgt ttacacttcc ttcgcctaaa ctaatcgtta ctatttgtga tccaatatct
    15781 gtccggctgt taactgttag ggtataatcc aatgattcgc ctaagacaac accggtaacg
    15841 tggagatttc caaccgaaat cgagtgactt tgggcatcat aattaaaggc agcgtcatcg
    15901 acagtaatca ctgcgttagc tttatagatg gtataagttc ctgatgtgtt ggctatatca
    15961 gtaaatgaca acttgggatt tgctgctttg actttgtcta ttccgctatt cgttagttta
    16021 attgtatagc tgccagcatt aaccatattt tttgctgatt gtgcatctgc tgtgtaatcc
    16081 atactgctaa gtgccacttg tactggagta agcgaactag tgacaccctc tgctagcttg
    16141 acatggattg acgggacacc tgcttttcca tcatatgtct tactgccact gagctctacc
    16201 gcaccgctga tttgcttaat cgtatagaca tcagatgtct gcacgatagt aaataaatag
    16261 tttgttctgg cagctagttt agctagtccg ctttttgtca attgccaaga cgtataggtt
    16321 ccaatttcag taggcgcagt tacttcaact cccttttcat tcatcgcttt gaaatcagtt
    16381 ggattccatg tgatttgatc aatactgaga tcattgttta aaagggatgt tgattctgtt
    16441 ttatcattaa aggcatattt aacgatcggt acaacagaaa gaccatcata gtacttactg
    16501 ccatttgcat tgattgatac tgttgcattt gtcttataat ataggatgac ttcagaaatc
    16561 tgttttccat ttgcgtcctt tacgattaca tttccatttg tatctaaact agctaaaaca
    16621 ctcattgctg attggttctt tgtttctgtc gctgaaacag ctgtaaaggt atatccgttg
    16681 atagtaggcg tattagtcgt caggtcttgt gcagcacttc cgtaagtaag attcattatt
    16741 ttagaaggag caatcatctg tccaaaatag tcttgatact taatagtgat tggtgtttgt
    16801 ttgcctgtat aggtcaccgt atcgacgtta ctttctaggg ctgtgaaaga accgtttgtt
    16861 tgtgcaaaag aatagcccgt tactgctgtt ggagtgataa ccactttgtc acccacatgg
    16921 attccagata atgtagtccc gtacgttccg atttttgctg ctccaccatt gactgtataa
    16981 gaaaaagttc ctgtccgatt cgcattgacc tgaaccgttg ctgcttgata ggttggaaaa
    17041 tttgaaacat ttcccttacc atcaacgatc tgcccatttt tgatcgagta ccccgtgaat
    17101 ggaatatcat ttgctaactg tataccgatt gaaaaagtac tcatacctcc tccggcagga
    17161 agccctcccc atgttgaggg tgtaaaagaa taacttttat ccgcattggg tgtaactgaa
    17221 tcgatcgtat ttccagcggt agccaccccc atatagatac tttttgggaa tgtgatagta
    17281 gtaccattta ctgtggagcc aataaacaga ttatggatat ctggacggtt atcaataaaa
    17341 gcgattgctt tggttacgcc ttgtaacgca gttttatccg cactcatcga tccgttaacc
    17401 gcaacaatga ctccatcttt ggcatatatc actgtatatc catctggtat ggtatgtccg
    17461 ttgaaattcg cagtggccgc aacagtacta aatgtctggc ttctacctgt ttctgaataa
    17521 gctttctccc ctgctgcttt tgctgctgtg atttcttttt ctgtcggatc aatcagttga
    17581 gtcgaggatg tggttgaggt tgtctcgttg ttgctagact gattggtgct ttctatggac
    17641 tgtatttcag aatagggtgg actatttgtc tcctctgtcg tttggttagc aaaatttgac
    17701 gtttctgtat aaacgtttac ataaatactt gataagctcc ctaagaaagt aaaaatcaag
    17761 atgatcgaaa tcataatggg atgtaagtat tttcttttag atacagcttt gagtctagaa
    17821 acaaaatgtt tttgacatat acgttggatt ttattttgag ttttcttaat cattttcatc
    17881 cctcctctca ataaaaaatc atcaaataat cctttacacg ttattctaaa tttaattttt
    17941 attattttat tgatgtatag aaagtttggg gctttttttc tctttttatt ctaaggttat
    18001 tttagtcttg tcctttaata caaagatttt atttttaaat aaaaaatact ctttttttac
    18061 gattattgaa aaaaaaagat aaaacttgat taattgaagt attgcttaaa tttggaagct
    18121 atgagggaag aataaaagag ttaggacggg attatctact atttttcttt gttttaaata
    18181 tttgttatct ttgaacataa aagagaaatg tgtcgactgc agtgttgtgt ccctcatcac
    18241 gaataaacgg tgttcaatta gctgatcttg tattcactta aaaaatggta aagtacgagt
    18301 tgctattccc cattttcaat tttctaacgc tcaggacaaa atactgtttt cacaacctca
    18361 ttggaataaa agcatatata ttgtttcaag aacgaaatct tgttatcttt ttaaagggca
    18421 tctgtccaaa atctaatttt aggaggtacg ttttggtatt tattcgtaca aataaaagag
    18481 aattatcttt attcatgtaa cgcatccaat tgattttttc atgtacgctc ctggaacgat
    18541 tttactgacg attgcttatt taactgcgaa tcgctcatta gcttttatca tagctatcca
    18601 tattttgaat aacgttcttg gctttgtatt atagatacag atgacaaaaa aagttcaagt
    18661 atgcggtgta gaaccaatat cgcatacttg aacttttttc aatgagtata aattaaaact
    18721 tctaattttc aattcccatc atctgatatg cccgaccgtc tgaacttctt ttgaaaaagc
    18781 caaatgtgat tagataacgt ctttgttcga cataatcgcc actagaaaat acgttcagca
    18841 gtatcgaatt aacctctgtt tctgtataag tcactccatg gtcaaagcgt ttcaagactt
    18901 ctttcaatag gatgtatttc ttttttgttg aacttggtac ttgttttact tttccatcat
    18961 tcatgaatgt gtctaaaact ttcatctttt cttgctccgt ataagtataa accatcttct
    19021 ttctcctttt gattctaaga atactccatt tatgttagaa tattctggat tttttattaa
    19081 agcggttact cttaagaaag atattatcat agtgctcttt tttttactac tacttatagg
    19141 tagatttatt ctaatccatt attctcccct accaataatt aaagaaaaaa ctggatcagg
    19201 gtgttcaaat tacatgctaa gaaaaaagaa cccttgaata ccaagggttc tttctcagtc
    19261 tgataacaat gattaacgac ggatttcttt gatacttgtg aaaagtcgtt aaagtattga
    19321 tataaaagga tttttattac ctctgactac atattgacta atttgttaaa aaatcgtttt
    19381 tcaagaatcc tgtaatacca gtgctttcac cgttttttta actctctaaa gaactaaaag
    19441 caatcagagg ttttaccttt tcatttgacg ttaagtggcg ataaattttc gaagttgttt
    19501 ggtcagtatg gcctaagcga tctttcaaga cttcccagct acagtgttcc gctactaagc
    19561 ttgccattgt atgacgagct aaatgagtat gaaatggctt attaattcct gagcgattca
    19621 cgcaccgttt gacgtgatca tttacatact ctcgacgata aggaacacca cgtttactag
    19681 aatcaagata cacaaacaaa tatgtttctt ctataataaa cctgtaatgt tgcctcatct
    19741 cacccaaagc cttaatcaac tgttgtagct tttccataac tagaggagtt actagaactc
    19801 gtctagcaga actaactgtc ttagtagttt caattcgaaa atccttactc ttacctttaa
    19861 ctgccgtttg cttatagaac agaatttcat ttcttttgaa atctatatct ccaggctgta
    19921 gagcaagcgc ctcgctgact cggcagccag tgtaaaatag aacatggaaa agtacagaca
    19981 tcggtaattc ctcatgaaca atgccataat tcaaaaaagt tctcaattca tcgacagtaa
    20041 gaaacttgtc ctcaatatta tttatggctt cttttaaatc agttaccgtt aactgatatt
    20101 ttggcattct cacagacttc attggatttt cacttatcaa attctttctt tgacaatatt
    20161 taaaaatcat atttagaact tgaataagtg attgtaaact atttttggca tagccaacat
    20221 ttgttccatt aacgccacat tcctttaagg taaaaagcaa ttcttgaagg cactctggtg
    20281 tcaaatcaga caacttttta tcaccaatcc atcgaacaat aatttttaat tgttcctctc
    20341 gcttatcata ggttatttcc ttttgttcat ttaacgaacg gtaatattgg aaccattgct
    20401 cacctacaac actaaacttg tcattgcttg caacaatttt tttcttaagc ctttgttgtt
    20461 tctccatttc cagataagcg agttgcgcct cacgttttga attaaagcca cgtcttgttg
    20521 ttcgatatgc ttgaaagtac catgtgatcc taccagtaga actgatttgc ttcttgaatc
    20581 gatctgtttt ttccatttat tgattcctcc tattttgaag gaacccaaca agcagaaacc
    20641 ctttggaaat ctttctatct atgtcatcat tgtaccgcat cttagaaaga aaatgtaact
    20701 tataaagatc gaagtagtcg caatttttct cgatagtcat tcgaatcact ctttctcatc
    20761 cattctaaaa catcatcacg aaaatagtgt cctcgaatcc cgtaccaaca gggaggaaac
    20821 tcaccaagtt ttactaaacg gttcagtgta ctatcactta tctgaaatag tcgctttaaa
    20881 tcagtatttg ttaataccag aggtaaatga ctgactgcaa gcaatttttc cgtgtaatct
    20941 tccagttttt tttgtaaaat tgaatagaac tctatttcca gagaattaac atttgtttta
    21001 acttccaact ccatcaccct tctctctcaa aatcaaaacg accaccacgg taccccttaa
    21061 aattgtaaaa aaacactcca gtactccatc aaaacggact agaaaagagg aatttttaat
    21121 atgaaacaag gaattgcaga cataaaaata attaaagaaa ttcttgaaaa atctacggct
    21181 aatgcaatag cattcggaac aggaatcaac ttgagtacag taaaaaaact taaaagtgga
    21241 gagagagctg aagaaaaatt aaatcttgcc gatgctatta aaatcacaga atttggcatg
    21301 aaaaatatgc caaccaaaat cgaaatatgg aaatagtagt ttttctgatc tatcagctgt
    21361 tttgccaaag cacataggaa tctcacctcc ccccagtaat ggcgggccga tttggttacg
    21421 gaagtatcat tatcgtagtc gcgattctca tattaaaatt tgtcgcttaa aagctaacct
    21481 tgtcatggcg taactagaga atcaaaatct acatgtactg atagatttgc tattcatttg
    21541 tcaaagagcg ctaggctatt ttcagcctat ggaaatcctt tattttgacc cgataaaaaa
    21601 cttccataga atgaaaagga aagggaaaaa atactttaac gagttgtatc aaattcaagt
    21661 atcttctcaa tcaattttgt ttccagttgt ctacgcatat attcatctac atacataacc
    21721 attccttttt cttcttcata aactggtttc atggctaacc gtgaaatata attttgatat
    21781 tttgacagaa cgatggacat ggcaattgaa tcaccagaag ctgcggcttt gattgtcgtt
    21841 agtggtatga atggtatata tcgtttattt tgcttcatat ttgacaccca aatactttcc
    21901 tagctcttcc aaagccattt gtcgttggta ccaaacactg ccgagacttt tcccaataat
    21961 atcgccaatt tcacgatcat taagaccgat gaagaaggac ataaaaatga tttcttgtct
    22021 ttgactaggt aatgctgcaa tcgcatttgc caactcctca ttggaaataa agattttcat
    22081 accaaggaca ataaaagtac cactactatt caaatttggt tccaaataat agaactctgt
    22141 acctaaccct ttttgttcca atatttccat tgatatttgc cgttggcgaa atctagcgta
    22201 cttcttttga atatttaacg cctcattgca gactactttc ttacaaaaac tgtcaaacgt
    22261 atgttgaatg tgggtttcct ctgagtcgcc cataatattc tccccctcaa aaaattcatt
    22321 caactcgttt tacttctatc cctttccatt attactacaa tctagga
//
LOCUS       DADGKS010000045        22322 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.045, whole genome shotgun sequence.
ACCESSION   DADGKS010000045 DADGKS010000000
VERSION     DADGKS010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22322
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.045"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(233..1081)
                     /locus_tag="JXV47_001816"
     CDS             complement(233..1081)
                     /locus_tag="JXV47_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAX1487856.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(1305..3245)
                     /gene="thrS"
                     /locus_tag="JXV47_001817"
     CDS             complement(1305..3245)
                     /gene="thrS"
                     /locus_tag="JXV47_001817"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HAX1487857.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3582..3761)
                     /locus_tag="JXV47_001818"
     CDS             complement(3582..3761)
                     /locus_tag="JXV47_001818"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HAX1487858.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3808..5631)
                     /gene="cadA"
                     /locus_tag="JXV47_001819"
     CDS             complement(3808..5631)
                     /gene="cadA"
                     /locus_tag="JXV47_001819"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAX1487859.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5909..8188
                     /locus_tag="JXV47_001820"
     CDS             5909..8188
                     /locus_tag="JXV47_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAX1487860.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8281..8928)
                     /locus_tag="JXV47_001821"
     CDS             complement(8281..8928)
                     /locus_tag="JXV47_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487861.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(9107..9826)
                     /locus_tag="JXV47_001822"
     CDS             complement(9107..9826)
                     /locus_tag="JXV47_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAX1487862.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9957..11108)
                     /locus_tag="JXV47_001823"
     CDS             complement(9957..11108)
                     /locus_tag="JXV47_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HAX1487863.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11325..12065)
                     /locus_tag="JXV47_001824"
     CDS             complement(11325..12065)
                     /locus_tag="JXV47_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAX1487864.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(12069..12392)
                     /gene="rsfS"
                     /locus_tag="JXV47_001825"
     CDS             complement(12069..12392)
                     /gene="rsfS"
                     /locus_tag="JXV47_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HAX1487865.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12449..13042)
                     /locus_tag="JXV47_001826"
     CDS             complement(12449..13042)
                     /locus_tag="JXV47_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAX1487866.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(13026..13673)
                     /locus_tag="JXV47_001827"
     CDS             complement(13026..13673)
                     /locus_tag="JXV47_001827"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HAX1487867.1"
                     /translation="MNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHLV
                     MAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIELA
                     RGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPGY
                     TTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13686..13997)
                     /gene="yhbY"
                     /locus_tag="JXV47_001828"
     CDS             complement(13686..13997)
                     /gene="yhbY"
                     /locus_tag="JXV47_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HAX1487868.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(14013..15122)
                     /gene="yqeH"
                     /locus_tag="JXV47_001829"
     CDS             complement(14013..15122)
                     /gene="yqeH"
                     /locus_tag="JXV47_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HAX1487869.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(15119..15646)
                     /locus_tag="JXV47_001830"
     CDS             complement(15119..15646)
                     /locus_tag="JXV47_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HAX1487870.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15826..16611)
                     /locus_tag="JXV47_001831"
     CDS             complement(15826..16611)
                     /locus_tag="JXV47_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HAX1487871.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16604..17473)
                     /locus_tag="JXV47_001832"
     CDS             complement(16604..17473)
                     /locus_tag="JXV47_001832"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HAX1487872.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17474..18853)
                     /locus_tag="JXV47_001833"
     CDS             complement(17474..18853)
                     /locus_tag="JXV47_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HAX1487873.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18861..19280)
                     /gene="fabZ"
                     /locus_tag="JXV47_001834"
     CDS             complement(18861..19280)
                     /gene="fabZ"
                     /locus_tag="JXV47_001834"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAX1487874.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19305..19781)
                     /gene="accB"
                     /locus_tag="JXV47_001835"
     CDS             complement(19305..19781)
                     /gene="accB"
                     /locus_tag="JXV47_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HAX1487875.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19784..21019)
                     /gene="fabF"
                     /locus_tag="JXV47_001836"
     CDS             complement(19784..21019)
                     /gene="fabF"
                     /locus_tag="JXV47_001836"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HAX1487876.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(21038..21775)
                     /gene="fabG"
                     /locus_tag="JXV47_001837"
     CDS             complement(21038..21775)
                     /gene="fabG"
                     /locus_tag="JXV47_001837"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HAX1487877.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21787..>22322)
                     /locus_tag="JXV47_001838"
     CDS             complement(21787..>22322)
                     /locus_tag="JXV47_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAX1487878.1"
                     /translation="VAVMNAPIETIEESCHEASKYGIVSPANYNTPQQIVIGGEEKAV
                     DEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFSEPSFPIISNTTT
                     EIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVLSGFMKKIDKTIP
                     VLRVENKQTFDETIAIL"
BASE COUNT         6153 a         4956 c         3901 g         7312 t
ORIGIN      
        1 aagaaaaaat gggcggagca agaaattctt tacctaattt caagataaaa tcaacttttt
       61 gtttcacagc aatcacttaa agttacatat ccaactattt ttttcattaa aaaataaact
      121 tatttttgaa aattatgttt tcttaagtcg tgaaacactt tgatggatca tttatttgtg
      181 gaaaactacg ttttgttatt ctaaaaaact tatataaaaa atagtaaggt ttttatttcg
      241 aatccataaa atattcttgg attgcttctc gtgttttttt cactttttcg ctaagctttt
      301 cgtttttagc catatagaaa taaaaaatga tatcgatcgt agcaaattgg gccaaaagtg
      361 aattagttgc cgcacttcga ttcgtgattt cttttggtct agatgtttgt acgagtacat
      421 cggctatctt gctaagcggg ttatttccaa attgcgtcaa cgcaatgatt tcgatattca
      481 tgcttttcgc cagctcggct aatgcgacta catctgcact tctacctgag tttgaaacaa
      541 gccaaagcac tttctttttc tcattgctga caagttgcgg gagcaagacg tggatatctt
      601 tttcaaaaat gattggctta ccgacacgag accatttttg cagaatatct tctactacta
      661 aagaagaggc gccaacccca tataaaaaaa cagtctctgc cgattccaaa cactctacga
      721 ctttttggat cgtttcttct tctagaatat ctactgtttc ttttatcgct acttgtgcat
      781 tgttaccaag tttgtttttg atagagtaaa aggactcatt tgcttctata tcactaaaac
      841 cttcatcgat tccagtctgt agttctgttg aaatcgtgat tttgaagtcc gtcagacttt
      901 gaaaaccgat ttttttggaa aaacgtacaa ctgtcggcgc actcaacccg gaagcttctg
      961 ctaattcatt agctgtcatt gtagggacct tctcaatatt accgataatg tagttggcca
     1021 actttttttc tgctgaagaa taatcttcca tcatactttc aatacgacta attacgctca
     1081 taagttcctc caccctttta atgatagtct atgtaagtat accatatcag acccttattc
     1141 acggtcgtat actggataaa aaacaaaaaa acaatccgcc caacagaata tcttatccca
     1201 tcaatcccac agattctatt gagcatctgt gtctttgagg aatacctgtt atctattgtt
     1261 cggattgctt tctatctact acttttttac aggaaattta cctattagtt ttctctgctg
     1321 taatttttga cttctgcttc catagcatca ataaagatat tcaaatcttc tacagctgtt
     1381 tctttacttc cataacgacg tacgttcact gttgcatctt ccaattcctt gtctccaaca
     1441 actaattggt aagggatctt ttgtgtttga gaggcacgta tcttatagcc cattttttca
     1501 ttacgatcat caacttctac acgcaacccc ttcatttgca aacgttcttt gatttcataa
     1561 gcataatcgc catgtgcatc aacagaaaca gggatgattg ttgcttgtat aggtgccaac
     1621 catgttggaa aagcgccttt gtatacttct gttaaataag cgacaaaacg ttccattgta
     1681 gaaacaattc cgcggtggat aactactgga cgatgcgtat tttccccgtc ttctccaaca
     1741 tatgtcaaat caaagcgctc tggcaataag aagtctaatt gtatagttga taatgtttct
     1801 tctgtaccaa gagctgtttt gacttgaaca tctagttttg gtccgtaaaa ggctgcctcg
     1861 ccttctgctt caaagtaatc tagttctaat tcatccatag cggctttcag cattgcttgg
     1921 gctttttccc acattgcgtc atcatcaaaa tatttatctg tattgtttgg atcgcgatag
     1981 ctcaagcgga aacgataatc tgtaatattg aagtcagcat atactgccac catcaattca
     2041 agcgtacgtt taaattcatc tttgatttga tcaggacgaa caaatgtatg accatcattc
     2101 aacgtcattt ctcgtacacg ttgtaaacct gacaaagcac ctgatttttc atagcgatgc
     2161 atcattccta attcagcgat acgaattggt aattcacgat aagaatggat cgtgtttttg
     2221 tagaccatca tgtgatgagg gcagttcatt gggcgaagaa caagcatttc gccatctccc
     2281 atatccattg gcgggaacat gtcttcttga taatgatccc agtgtccaga tgttttgtac
     2341 aactcaacat ctcccattat tggtgtatat acatgttggt aacctagact aacttctttg
     2401 tctacgatat aacgttcgat cgtgcgtcgg attgttgccc cttttggaag ccagaatggc
     2461 aaaccagaac ctacttctgg ggaaaccatg aacaagtcaa gttcttttcc tagtttacga
     2521 tggtctcttt cttttgcttc ttcacggaga cggatatatt ctttcaaagc tttcttgtca
     2581 aaaaaggctg tcccgtatac acgttgcatc atttgattgt ttgagtttcc acgccaataa
     2641 gcacctgcca ctgataataa tttaaatact tgtatacggc cagtggatgg aacatgtggt
     2701 ccacgacaca aatcgatgaa ttcgccttgt tgataagcag taatcacttc ttcttctggc
     2761 aattcactaa tcagttctac tttgtacgga tcacttgcaa aaatttctaa tgcttcctgt
     2821 tttgaaagaa cacggcgttc gatcggcaga ttttctttga cgattttcat catttctgct
     2881 tcgattgccg gcaaatcttc tgcagttact tggttttgtc cattatctgt atcgtagtaa
     2941 aaccctgaat cgatagctgg tccaacgcca aagtggatat ttggatagag gcgacgcatg
     3001 gcttgggcca tcaaatgagc tgctgaatga cggactaagc caagtgcatc ttcatggtct
     3061 ggtgtgatga tctcaatact tgcatcttcc tcgattggac gagtcaaatc aacgagtttt
     3121 ccgttcactt taccagctaa agcttttttt gctaagcttt ttgaaatgct ttcagcaatt
     3181 gccaatgttg ttgttccaga ctcaaattct ttgactgcac catctggaaa agtaattttt
     3241 atcataatag tttcctcctt gaaatgtttt gattgatcag atcatcaagc tgaaaaacaa
     3301 aaaaatccta gcatctcttg aaaagagata ctaggacgaa aagttcgtgg ttccacctaa
     3361 tgttcaaacg caaatgcgtt cctcaagcgt tgtaacggtc cgaccgccct tgcttcaaca
     3421 agggtttcga aagtggtcat cctttggttt tctcctggaa aagtttcagc ctagcttttc
     3481 ctctcttatc gaagactctc aaattcagtt ggctttctca tcaatcaatt atgtgtttat
     3541 ttaaccacta ataaatagaa aaatcaagtg ggaaactaaa cttatttttt ccattcccca
     3601 tttacaccgt atgttccttt tttcatctca ttgatgatga catggatgtg ttcttttggt
     3661 gcctgcgtgt ttttatgaac agcttccgtg atatctttca tcatattttc taattgttcc
     3721 ggactgcgac cttctactaa ttcgacatgt acgaatggca taatgctctc tcctctttct
     3781 gatcgttctt ttttcaactc gattctatca tactatgttt gtcttgggta ctgaatcagg
     3841 aaaaatggct ggatcttttt ttgctctcaa ggcactcaaa atagagaccg tatccacgac
     3901 ttcttgcaaa acagctccga ataatgcggg gattagtccc gtacttgcaa ttaacatcaa
     3961 aaaaatacaa ataaagatgc caatcagtac agactgtttc gctattctca tcgtatctct
     4021 tgaaatcact actgcttttg ctacacgcaa gagatcatct ttcaagatga ccgcatctgc
     4081 actttcacta gcagctgtag aaccatgagc ccccattgca ataccgatat ctgcagcagc
     4141 aagtgctggt gcgtcattca cgccgtctcc taccatcgca acaggtcttt gatctttagg
     4201 gatactttct aaaatggtca gtttatcttg aggcaagcta cgggcatgta cagaatctaa
     4261 ttggactttt tctgcaatcg tttgagcaat ggcagatcca tccccggtga tcatcatcaa
     4321 atttttcaca tcaagttttc ttagctcctt gattgtcttt gctgcttctg ggcgaatctg
     4381 atccgaaaat aggatcgttc ctgcaaaaga tcgatcaatt gttacataga ttgctgtatt
     4441 ggacgtttct atttcttcag ctgaaacaaa agaggcacgt ccaatcttta cttcatgatt
     4501 attgactact gcttggattc cttgaccggt cacttctttc agttgactaa caggatacag
     4561 ttggctgttt ttcacgttgt tcactaacga acgagctaag atatggctag attcctgttc
     4621 tgcactagct gcatacagaa gtagctcttc tttttttatt ccattgactg gctgaatcgc
     4681 ctctacttcc aatatccctt tggtaagcgt tcctgtttta tcaaaagcaa tcgtttttgt
     4741 acgtgcgagc ttttcaatcg ttgttccagt ttttacaacg atcccgtttt tacttgaacg
     4801 gctcattcct gcaactaaag caatgggcgc agctagaatc agtggacaag gtgatgccac
     4861 taccagtacc tcagcaaatc gtaaagggtc ttttgagaac caccaagaaa taccaccgat
     4921 caaataagca atcaacgtga aagggactgc ataacgatca gctaaacgga caaatcgggc
     4981 aggcttttct tttgattctt cgactagttt aataatcatt tgatactggc tgtctgcggc
     5041 acgtttttca gcgatcattt ggatcgatcc gtctccattt aaagaccctg acataatctg
     5101 atctccaggt ttcttggttt ccgggcggga ctcacctgtc aaagaagatt catcgaccga
     5161 agattctcct ttggtcactc gaccatctgc gggtacaagt tcgccaggct tgactagtaa
     5221 ctggtcatca atatttattt catcgattac tatatcctgc aattttcctt ctttgaatcg
     5281 atgggcaatt cttggggtgt tatctaacaa agactgcagt tctttacccg ctcgtttatt
     5341 cgcgtaatcc tctagactat ctccgcccgt aagcatgatc aatatcatca aactagccca
     5401 gtattctttg acggctaatg ttgcaaggat tgcggtaatc gctaatacat ctacgccata
     5461 tcttcctgaa cgtaacgtct tgatcatttc caaaaacatc aagaaggcga gaatccctcc
     5521 agtaaatgcg acaatcgcaa atgcaagggc cggctggtga aaaacaaatt cacttaataa
     5581 agctatccca ccaataagca aagtaagtaa aaattttttg aaatgtgtca ttgttttttc
     5641 tcctctttta tgtgacttag agaggttagt aataaatttc cagctgcctc tttcatctta
     5701 agcatagtcc ttgactagca ctttttaaaa caataggcct taattgaaaa caactatcac
     5761 tatcagcgtt tccaaaattc atcagttcta caaacaaaaa tattcagcaa ggattacttt
     5821 ttcgattcat cagttaaaaa gtaccttttt tcgaaaaact atgctatact tttaattcgt
     5881 tatttacggc ggaaggagca aacatgcgat gaatgagaaa caactagaac aaacgcacgt
     5941 ggatgaaacg atcgaactaa tccagatcga acaaaatatg ctggatacaa aacaacaaga
     6001 attgactcag gaaatgaatc attcgacaaa agacacagct aatcacaaga ttcgagctgg
     6061 ttccaatgaa gctttttatg aatctgctgt tgaatatcgc caacatgagc aggaattgct
     6121 tttgaaatac catactcttg aagcacagca aaaacgcctg caaacgttgt ctgtcatgaa
     6181 agatagtcct tattttgccc gtatcgactt taaagaagac cgtgaaacag aaacattata
     6241 tctaggtatc gcttctttaa gagatctggc agaagaaaca atcgttattg actggcgcgc
     6301 accaattgcc aatctttatt atgaaggtga gattggtccc gcattttatg aaactgaaac
     6361 agatagaata gatgtcgatc tgcagttgaa acgacaattt aaaatccaag aaggacgtat
     6421 tttatctatg gtagatacgt cggaagtaat caatgatgac tttttgctag agatattgga
     6481 tgaatcatca agcaaccata tgaaaaacat cgtctctacg atacaaaaag cacaaaatgc
     6541 aatcattcgg gacacaacaa gtaaagtaat gctgattgaa ggaatcgccg gaagtggaaa
     6601 gacatccgct ttgcttcaac gtattgcttt tctgttgtat cataatcgca agtggctcga
     6661 ggctgaaaac gttcttctat tttcacccaa ccatttgttt tctgattaca tctcgactgt
     6721 attgccttca ttaggtgaaa gcggcgtgcc tacacagaca ttcaaaaatt atttggtgca
     6781 gctgctgcca gagttttctt tactagatga acagcaacaa gaaagtggtt ttttgctagg
     6841 ggaaaaagat ccgatacaag tgatgaaaag cggattgacc ttagtcgatc agattgatcg
     6901 ctatatccaa ggcatcacaa actacggtcc cttgttccgt gatatgaaaa taaatggccg
     6961 tacgatccta tcaaaggaat cgattcgcca atggtataaa gaaacaaatg aacaattacc
     7021 tttacatcat agactttctc tattacaaac gaagctcctg aaaaaattag gcggtctgca
     7081 aaaagacgaa acacgtcagc aatgggtcaa agatctggcg gaagaacagc tccaagaact
     7141 atacgcaaca gatccaaatc ttgaatatac agaacaaaag gagcgttcat tacgtaaaaa
     7201 actggccaac caaatcgtac gtaaaagatt ccgtcgaatc catcgaggga tcatgaatta
     7261 tcaatttgtc aatataacga aacaatatct ccactttcta caaactgtgc cactttctct
     7321 tctaacacga cataaaatca gcgagaccag gtggcaggaa catttgacaa ctgttcgtac
     7381 acacttgcgt caaagagaat tgcgtcaaga ggatgctgta ctattctttt tactgatgcg
     7441 ccgaacatat ccagtgacgg ttacacacaa agctcgctat atctttattg atgaaatgca
     7501 ggatttcgca ccatcacaag tggcattgct gcaagccttg ttcccaaaag caaatttgac
     7561 tttctgtgga gatctaaatc aaaatgtctt tggaaatgaa acgatcgttg gatcattgga
     7621 agaccttttc gtggaccgtg aagtcactcg tttccaatta acgacaagct atcgctccac
     7681 aaaagaaatc actgattttg ctaatcattt tattgtgaaa gaacatcaag tagaaacaac
     7741 agcaagaaaa ggagaccttc ctttgctcat ccaaggaaca acagatgata tcaaattgaa
     7801 ttggttagca gataccattc gaacgactca gggaaaagcc cggtattggc gtacagcaat
     7861 catagctaaa acacaagaag aatgcgaagc tctttatgct caactgccag acgagttgaa
     7921 acaacaagtc cagctgattt taaatgagag tgactttatg aagcgttcca ttattttact
     7981 tccagccttt ttagcaaaag gtctggagtt tgaccgagtt ttcttgtggg atgtagatgc
     8041 agaacatttt tcttctcagc aagacaaatt gatcctttac accatgtgta cacgtgcgat
     8101 gcatgaattg acccttttta cctccaataa tgaaagtcct ttgttaaaca atatggatat
     8161 ttcatcttat gagaaaaaag tactgtaagt aaaaagacaa ctgctatcat taatgttagc
     8221 agttgtcttt ttatttacaa taataattgc agaaaaagta attcaatcat ttaaggtcat
     8281 ttattctata tataaatcca aatctgtttc aggatatttt aatttgacaa gcgaaataat
     8341 cattttcagt tcttccatgt tttctggata ttctgggtca aataccttgc tatgacggcc
     8401 aatcccgcca ttgtcgatca atcggtaaat tcgattccat tcaatgaatt ggtcaattga
     8461 ttggaaattg ctgattggat agccgccaca atccaaaatc tctgatacac gaaatgctag
     8521 gtatgcacta tcgatcactt tatttttttt cgtgtctatc ttctcatttc tttcgataag
     8581 aattttttca ggacgatgtt tcaagctcca ctctaatagt agaaagaaag cctccatccg
     8641 atactcttct tcaaataacc gaaaggctga atcagaacga cgaaaaagca gcggaatcag
     8701 ataattttgt ctataaatca gcattggtgc gcggtccacc atacactcta aataacggtt
     8761 cagataccct gtaccgacat agtttcctaa tcgatagcct tcaacgccga atcttgcgta
     8821 tttttgcgct aattttgaac aatcagttac gttcacagct aactcttcta ctttgcggta
     8881 accgcttaag atacgttcaa aaggttctaa agtgattttt gcttccatat tcttccccgt
     8941 ccatcttcca catacttcat atcatttcac atgatactta tgctctcatc ataccacagg
     9001 ttgaattaga aaagaaaata aatcacacaa aaaagcaaga caatctgtta gtgagattgt
     9061 cttgcttttc gaaaaagact gaatactttt cgttaaaact ggttgcttag tcttctaatg
     9121 ccacattatg gaacacatgc tgtacatctt ctagatcttc cagtgcatca atcatttttt
     9181 caaatgtttc ttgatcttct ggagatagtg ttacctcgtt ttgagggatc atttggatct
     9241 cagcgattga aaaatcagtg attccttttt cttttaatgc ttcttgtata ctatggaaat
     9301 ccgctacttc accgtaaacg atgatttgtc cttcttcttc cattacatcg cgaacatcga
     9361 tgtctttttc cattaggtat tcaaggatct cgtcagcgtc ttctcctgca aaagcaaaga
     9421 ttgctgtatt gtcaaacatg taagaaaccg ctccggaaac acccatgttc ccgccatttt
     9481 tcccaaatgc tgcccgtacg tctgctgctg ttcgattcac attgttcgtc aatgtatcaa
     9541 caatcaccat tgagccgctt ggtccaaatc cttcatagcg caattcagag tatgtttcat
     9601 ctcctgcacc ttttgctttt tcgattgctc ggtcaataat atgttttggt acattataag
     9661 ttttagcgcg atcaatgacg aaacgtagtt tttggtttgc atgcggatca ggatcacctg
     9721 attttgctgc cgcgtagatt tcaatcccaa attttgcata aatccggcta ttattagcat
     9781 ctttagcagt tttctttgct acgatatttg cccatttacg tcccatattt tcacttcgct
     9841 ttctgatttg atagtttcat aacgcaaaaa cgtcctgttc cattatactt gtgaatcacg
     9901 attctgtgaa gctttttttc tttcttcctt cattcttctc atttttagtc aattatctat
     9961 actcggattg ggatttgccc gaaattctgt tccggaatat tgcctcccaa ttgatagatt
    10021 tgatcacttc taactaacag ttccgcttct tgtgcctctt tttttccgat tcgggaataa
    10081 atagaaatct cttttttttc ttttaagaat cttcttccag catcggtaaa tccaagtagt
    10141 cgaagataat ttttattttg ttggacagga atctcttgct ttttgatatt cagcaagaca
    10201 taacaagata atcgttggat ccgtgtccat gtatatcttt ttgtttttac ctttgacaca
    10261 aaatcctcaa aactatcagc agttgcagct gctgttttca tgcgcgattc tattccttcg
    10321 gtcatctgat agatatctgt cagttccagc aaagtagaag ataacaaccg ataacgcaaa
    10381 tacggccaat aagattccca agtctgcagc gaacaagttg aaagatcttc ttctgtctga
    10441 ggcggcacaa gtccagctat tctttttcct tcttctaacg catggcgaat ggctgttgca
    10501 ctggctatcc tctgatctgt gatgattttt tcatgatagc ctgcactttt acgtcggatc
    10561 ggatgtaatt ccatagggtg gacatacttg gcattttcct ttgcataact taatcccaag
    10621 atatgatttg gcgaagaaaa atcaagcgta atatcgggat acagactgcg aaaaacctca
    10681 gtcatttttt gcggataact atacgtttga tcagacagtt cttgaaatgc ctcttctatc
    10741 ctatcttgat tctcttggac aaagcgtccg aaactgctgt aatcaaacga agtctcttct
    10801 tctgttccaa aacacaaact gtcacagtcc agtgtttgca agatttttac tgcaccttta
    10861 gcaaaatagt cagctgactg aaccgcccat tcgacgggaa gctccactac taaatccaca
    10921 ccattttgta aagcttcatt cgcgcgatgc catttatcga tgatagccgg ttcgcctctt
    10981 tgcaaaaaat tcccgctcat tacagcaatg acgacctctg ctcctgttat ttttcgtgcc
    11041 atttccacat gatagcgatg tccattgtga aaaggattgt actctacgat aatcccgcag
    11101 cttttcatgc gcatcctcct tcatagttat cgataaaaaa gaaatagaga caagtaaaaa
    11161 aaggcaaaaa tcggaaaaaa tacccgaact atataaacta ttctcgcaaa cacaatactt
    11221 ctgcgacgaa aagctgcact gcaagagcaa tgcctatatc gttcggatat ataatttatg
    11281 ttgaagattt attcttttct tgttaactcg agcaggcaaa accgctagtc tttgtatgct
    11341 acaaagaacc agcgctttga tttctctgat gctgcttcgt ctgtaaaatc agaaaatgct
    11401 tcgactttcg aaaagccgct gttttccagc attcttaaat aactttccaa tggataggta
    11461 cgctcttgat gtagttcatc ttcacgaata aatcgaccag acccttcttg ttcttcaacg
    11521 aaaaaggtaa gaaaatgttc gatgctgtgt ttctcgcttc ctggataact atcccacaaa
    11581 aaagcaaaat tatccccttg ataatgatag ctatattctg gaaaaacctc atctacttga
    11641 taggtggagt gtacgtcaaa taaaaatcgg ccattttctt ctaacgcttg atagacttca
    11701 tcaaacactt gctgtacctc ttgtctattt ttcatatagc acagcgaatc agaaaaacag
    11761 gtaattgcct gatattgtcc gatttctgat aaatcgagca tattgccttc cacaaattgg
    11821 atcgatgcgt cttcttcata tgctcgctgg ctggcaatca tcaacatctc ttctgaaagg
    11881 tctaaccctg tcactttata tccatctttt gcaaaggcaa ccgctaatgc tccagtaccg
    11941 catgccagtt ccaaaatatt ttttgtgtct tcttgtaaat gacgtttcga aaaagctaac
    12001 cattgctgat aaagtgtttc gtccatcact tcatcgtaaa tgaaagcaaa tgtttcataa
    12061 gccatatgtt aatccaacca ttcactaaga tcgactagcg gagcatctga ccatagtttt
    12121 tccagattat agaaatttcg ttctggcgca tggaaaacat gtacgatcac atctccaaga
    12181 tcgatcaata cccattttcc gccttctttt ccttcaatac gttttacttc atatttgttt
    12241 tcttcttctt tatcaatgat ttcttctgta attgcgttga tttgacgttc gctatttgct
    12301 gaacagatca tgaaataatc tgccaacaag gaaacatttc gaacgtctaa agcgataatg
    12361 tcttctgccc gttttgaatc tgctgcttca atcgcaattt ttaattgttc tttactatct
    12421 atgatgattt cctcctaata tgagcagctt atttttttgc tacccagtaa ttatatgttt
    12481 cgattgtttt tggataaatc tgttgttctt gcgcaagcaa atgggccaat gtatgttttg
    12541 tttcaaatgc tacagcttcg tctagatcag cccatgcaat ggctcgtgca tcttgtaccc
    12601 caggaaaatc tcgacctggt tcaatatagt ctgctacata aatgattttg tcaaggagac
    12661 tcatcttagc agccccagtc gtatgcaccc ggattgcatg aagaatctct gcatcggtga
    12721 ttcctaattc ccgctctaca aacgaagcgc caacaagacc atgccagatt gcattattat
    12781 aattcaataa ctccggatca aaaccgtctc ttacgattac cattttgaac tcctcatctg
    12841 gtcgttcttt tgcataatca tgtgtcaatg cagcaatact agctttttca ggagaagcac
    12901 cgtatttttt ggcaagagcc acggctgttt cttctactcc aagcacatgc ttgaagcgtt
    12961 gttcgctcat tctcatctgt attttttgca tcaggttttc tctagaataa gcagtatatt
    13021 cattactata gtccatattc atacaaccct tcattttgaa tataatcaat tactttatct
    13081 ggaacaaggt agcggataga acagccttct ttgatctttt gacgtatttt cgtggaactg
    13141 atgtcgatct caggtacatc tacccaaatt acaggatatg gagtatccgt tgtgtatcct
    13201 ggtcgacgta tacccacaaa gttgaccata gaagtcagct catcgatttt ataccatttt
    13261 ggcaaatatt ctaccatatc cccaccgata ataaagtaat aatctgtatc cggattgttt
    13321 tgcgtcaatt ccttcatagt atcataggtg taacttttcc caccacgagc taattcaatc
    13381 gtttcaatct gcaaaaaagg attgtcttcc accgctaatt ccaacatgtt gagtcgatgt
    13441 tttgcatcaa tcgtctgttt ctcatcaaca tgaggtggct gataagaagg catcaaaaat
    13501 acgcggtcaa gacctaaatt ccggccagct tgttcagcca tcactaaatg tgcaaggtga
    13561 acgggattga atgttccgcc caagatccct acttgctttt tcttctctaa gaattgaggc
    13621 atttcttcag gaaataattg tgaacgaaca aatgtcttag cttgcgtatt catcatggtc
    13681 actccttata ttgcttttac ttcttttgat agcctttgat acttttcttt tgtggaaggt
    13741 ttgtataata caataacacg tccaatgatt tggacgattt cgcaatctat ttctttttct
    13801 aatacttgag ctgcttcttc tgcaatctca tctgtatttt gaagtaacga tactttgatc
    13861 agttctcttt tttctaaagc ttcttcaatt tgaacgatca ttgctgaatt gatcccacct
    13921 tttccgattt gaaaaatcgg ctgaagatga tgcgctttgc tacgtaaaaa acgcttttgt
    13981 tttcctctta aactcataat tttccttctt ccttaaatca atgctttgcg tttcaataca
    14041 tctacaccct ttggcgccca gcccgcaatt actactggcg ctgttacagt gatccagcct
    14101 agaccggcaa aaacgatgtc tgttttttct ttcacagaaa actcaaaacg aacaagctcc
    14161 ggaaatgcct cgacttcatc aggacgagga ggctgtaata atccacctac atgtttttga
    14221 taaaattcgt ctgctttttc cagtttcgtt cgatgaatat ttacatcatt tgacacataa
    14281 gcaataaatg aagcacgatt gccgctgata aaatcaaatc ttgcaagtcc gcccaagaaa
    14341 agtgtttgcc cttcattcag ctgataaact ttaggtttga tttcttttaa cggtgcaatg
    14401 atccgcaaat cttttttacc taagtagtgc gccatttgat ggcgatggat aattcccggt
    14461 gtatcaatca aaaaatgccc gtcatctaaa ggaatctcga ttttatccaa ggtcgttcct
    14521 ggaaactgcg aagttgtgat tacatcttgt actcccgctg tatttttgat gatttgattg
    14581 ataagcgtcg attttccgac atttgttact ccgacgatat agacatcccg tccatcgcgg
    14641 tattcttcga ttttttctaa tagttccgtc atctcatgag atttcttagc actagttaat
    14701 aatacatcta ctggacgaat tcctgcttcg taagcacgtt ccttcatcca ttgtgttaat
    14761 ttagtttttt tcaatgattt aggtaatata tccactttgt tcccaactaa aagtactgga
    14821 ttgtcaccga caaaacggtg tagtcctggg attagtgaac cattgaagtc aaaaatatcc
    14881 accacattga cgatcaatgc atctttttgc cctaattcat tcagtaagcg caaaaagtcg
    14941 tcatccgtca atgagacatc ttgggtctca ttataatggc gtaatctgaa acaacgctga
    15001 caatagactt ccccggaagc taaacctttt tccaaagccg tttgcggcgt gtatcctaat
    15061 tcaccgggtt tgtttgtttg tataacggca ccacagccga tacattgtaa ttcttctgtc
    15121 attcgattcc acctcgccag cccatatcag ggtgttttgc taatagatag gccataattc
    15181 ttttttccca aaaacgatta aattgtgtct tccaactatc tgttgcgata atgggtttta
    15241 caaggatgct acgtatccct gcacgattgg ctccacgtat atcagtcata atctgatcgc
    15301 ctaccattac tatctcatca tctgctaaat ccaattgttt ctttgctatg ttgatccctc
    15361 ttgctaaagg tttcattgct cgtgcaacat acaaaagatc aaatttttca atcgctcgcg
    15421 cgacacgttt tgaattattg tttgaaacaa caacaacagg gattcctgca tttttcattt
    15481 ctaaaatcca agtaagcaac tcttctgttc catctggatt attccatgca atcaacgtat
    15541 tgtctaaatc ggtcaatact gctttgatgc ctagattctt taattgggca ggtgtaatct
    15601 gatagatggc ttctaccatc catgttggtt tgtaatttga aaacatgctg tctcctcatc
    15661 tgcaaaaaat gaaggagcac ataaagtact cctcaacccc gtattatact gcatatcagc
    15721 aaaaaaaact acctctatac tcgttcgtct ttcagaaaaa gcatttcttt acaaaatgac
    15781 caaaaataaa gattgatcac agaaaaattt agaaacaaaa aacaactaat attggcggaa
    15841 cctcttgtat cgtttttcca gtaatttatg ctgatctaat cgaacaagtt ccgtcaatct
    15901 ttcaatcaac gcttttttca taatgtgtgc gactttatat cgtggcaact gctcgccgtt
    15961 gaacgtttca ggaataactc gatcaacgat tcctaactcg cgtagttctg gcgcagtaat
    16021 tttcatcaac tcagctgctt ctgcggcgcg actaccgtct ttccacaaaa tcgacgcaaa
    16081 tccttctgga gaaagcacag cataaatcgt ttcttccagc atccagactt catccgctaa
    16141 acctagagca agggcaccgc cacttccacc ttcaccaatg atgatggcga tgatcggtac
    16201 ctttaaatca gacatttcga gcagatttct ggcaatagcc tctccttcgc cgcgctcttc
    16261 tgctcctaca ccgcaatatg cacctgctgt attgatcaag gtaatcaccg gtctattgaa
    16321 cttttccgct tgtttcatca gtcgtaaagc ttttcgatag ccttcaggat ggggagaacc
    16381 aaaatttctg cggatatttt cctgcagatc ccgtcctttt tgaataccga tcactgttac
    16441 cggtttgcca tctaatcgag cgattccacc aacaatcgct tcgtcatctg caaataaacg
    16501 atcaccatgg cattcctcga aagaatcgaa gatctcttca aaaaaatcca agcttgtcca
    16561 tcgttcttta gctcttgcta actgaacgac atcatgtgct gtcttatcca cgatctatcc
    16621 atcctttctg tgtatgcaat tcaagaagcg tatggatttt ctgtttcaat tccatgcggg
    16681 gaacaatctg atcgacaaaa ccatgagata ataagaattc agccttttgg aaatcttctg
    16741 gaagttcctg cttgatcgtc tgttcgatga cgcgtcttcc agcaaaaccg atcaagcttt
    16801 ggggttctgc tagaataata tcgccttcca ttgcaaaact ggcagttact cctccggtcg
    16861 tcgggtccgt taaaacagtt agataaaaaa gaccttcatt gctatgccgt ttgacagcag
    16921 cagagatttt tgccatctgc attagagaaa agattccttc ttgcatccgt gcgccacctg
    16981 aagctgtgaa caagacgact ggaagacttt cctttgttgc tcgttcgaat aatctggtga
    17041 tcttttctcc gacaatcgtt cccatacttc ccatgataaa attaggatcc atcactccaa
    17101 taatgaaggg aatcccctga atggttgctt taccagtgag gactgcttca tgaagtcctg
    17161 ttttatcttg cattttttta attttttccg tatattcggg aaatgctagc ggatctttgg
    17221 ttacaagatc cgtatcccat tcttcaaaac ttttttcatc aataatcaaa gctagacgct
    17281 gccatgcacc gattcgaaaa gcgtatccgc aatgagggca tactttttct tcaccgatgt
    17341 ctttcgtata aaggatatgt ttgcaatttg gacactttgc ccacatgtta tcaggaacag
    17401 atggcgagtt agcaggtttg ctctctctat taggattgat ccgaatatat ttctttttct
    17461 taaacagagc catctatgcg cctcctatct ccgtttctgg tgtccaattc ggtaaaaatt
    17521 cttcttgtaa aaatgctgtg ctgtaatcac ctgctatgac tgcaggatga ctaatcaaat
    17581 ccatctgaaa ttctgcgttc gtgatgattc cttctgtgat aaattcactt aaggctcgct
    17641 gcatcttcat taatgcttca aaacgcgtat ttccatggac gattattttt gcaatcattg
    17701 aatcataata tggcgggatc gtatatcccg ggtaaactgc actgtctact cgcagtccca
    17761 tcccacctgc tggaagcagt aagttttgga tcttccctgg agaaggagca aaatggaaag
    17821 caggattttc tgcattaatc cggcattcga ttgcgtgtcc ttggaatact acttcttctt
    17881 gacacacatt caaaggctca ccggctgcta tctccacctg tttttttact aaatcgattc
    17941 ctgtgaccat ttctgttact ggatgttcca cttggattcg agtattcatt tccatgaaat
    18001 aaaaatcgcc ttcttcatcc atcagaaact cgatcgttcc ggcattttca taattgactg
    18061 ctttagctgc tcgaacagca gcgtctccta gtgcttctct ttttgtttgt gagatcacta
    18121 cagaaggaga ttcttccagt actttttgat tgttgcgttg taaagaacaa tctcgctcgc
    18181 ctaaatgaat gacatgacca aatcgatcac ctaagatctg aacttctata tggcgagcag
    18241 gataaatgat tttttccaaa tacatatcat catttccaaa tgccgctgct gcttcttgct
    18301 gagctgaaga aaaatgctgt gggagctctt cttttgattg aactttccga atgcctttcc
    18361 cgccaccacc tgcagctgct ttcagcatca ctggataacc aattctgtct gctatttcca
    18421 atgcttcttc tactgtagat aatacaccag tacttcctgg aatgactggg acatttgctt
    18481 cttgcatcaa ttgacgcgca ttgatcttat ttcccattgc atcgatcgtt gcacttttag
    18541 gaccaataaa tgtgatattg cactcttcac acatggaggc aaatcggcta ttttcagata
    18601 aaaaaccaaa tcctggatga attgcttcgg cttttgtcac gattgcagcg ctcagtactt
    18661 cctgaacatt cagatatgaa tcaacggctt ttgccgggcc aatgcagatt gcttcatctg
    18721 ctaactgtgt atgaagtgct tcggcatctg cttctgaata tatcgctacg gtttggatcc
    18781 ctagttcgcg gcatgcacga atgatacgta cagcgatttc accgcggtta gctatcaata
    18841 ctttagaaaa catatttcac ctatccaatc ataaaggtta attccgcttc ggctactttt
    18901 ttaccgtcta ctttagcgat tcctttgcct attccggctg aagctttcac tttcaatatc
    18961 tcaacttcaa ggtataaggt atctcccggt gtaactttct tacggaattt tgctttgtcc
    19021 aatccgccga aataagccgt ctttcccttg aattgttcaa gagaaagtaa tgcaactgct
    19081 cctgcttgag ccattgcttc aacaatcaat acccctggca taacaggttc ttctggaaaa
    19141 tgtccttgaa aaaagggctc attgatcgtt acatttttct tagcaacgat ccgttctcct
    19201 tcaaccattt cttccactcg atcaatcaaa agcattggat aacgatgtgg aatgatttct
    19261 tttatttctt gtatgttcat tgttttccct ctttcctgct ttgcttattt ttgctgaatc
    19321 ctaaagagtg gctgtccata ttcgacaact gactcgtttt ctacaaggat ttctgtgatc
    19381 actccgtcgg cctcactagt tatctcattc atcagtttca tcgcttcaat aatgcagata
    19441 acttctcctt tggcaacttg atcacctact tttttgaaag ctggtttgtc gggcgctggt
    19501 tgcagataaa cgattcccac gattggcgaa acaacctcga ttccatcaaa tactgccgat
    19561 tctttttctt tcattatttc tggagcagtt gttgcttgtt caggtatgac attgactggc
    19621 tccgaaactg gcaacgtttc gtttgtttga accatattca tgcctcgact tgttttattt
    19681 ttattcatat acaattcaaa ttgaccttca cgcaaatcga attccgttag cgaggattga
    19741 tcaaattgac tgactaattc tctgatttca ttgatatcca aaattattcc tcccagcgtt
    19801 tcatgcacag aaccgcatta tgtccgccaa accctaatga attactcatt gcataagtaa
    19861 aacttgcagg tttgctttcg tttttgacaa ctgtcaagtc aatctcagga tcttgttttt
    19921 ctacattgat cgtaggtggg ataaattgat gttctaatgc cagcaaagtt gccaaggctt
    19981 cgatcccgcc ggctgctccc aataaatgtc cagtcatcga tttcgtgctg ctgacgtaag
    20041 tatctctgaa attttcacct aatgcgattt ggattgcttt tgcttctgcc tggtcattgg
    20101 ctggtgtact tgttccgtga gcattgatat atccgacttg ttccggctgt acaccagctt
    20161 cttccatcgc aagcttcatt gctttagatg caccagaacc atctggagta ggagctgtca
    20221 tatggtaagc gtcacagttt gcaccgtatc caacgatttc tccatagatt ttggcaccgc
    20281 gagcttgtgc atgttctaaa gattcaagaa ctagaacgcc tgctccttca cccatcacaa
    20341 aaccattccg attttcgtca aacggaatcg aaccacgatt aggatcagtt gattctgaga
    20401 gtgctgttaa agctgcaaat ccagcaatcc ccatctcaca aatcgttgct tctgttcctc
    20461 cagcaagaat gacatcagaa tagccatgtt tgatgttacg gaatgcttcc ccaattgaat
    20521 tcgttccgct agcacaagct gttacgatag ctgtacaaat accttttgca cctacacgca
    20581 aagcaatatt tccagctgcc atgttggcaa tcgccattgg tacgaacatt ggagaaactc
    20641 gttttgcacc tttttcatgt agacgaataa cttggttttc gattgttgga agaccaccga
    20701 tcccagatcc gatgatgacg ccaaaccggt cttgattcat tttttcttta tctaaaccgc
    20761 tcatctccat tgcttctaaa gcagcgtaga ttccatagat cgaaaacata tccattcgtt
    20821 tgctatcttt tttaataaaa tatttatcgt aagggaaatc tttgacttca cccgctaagg
    20881 taatccctgt ttctgaagca tcaaatttag tgatcggtgc gatgccattc gtcccctctt
    20941 ttaagctatt caaaaagctg tctgcgtcat ttccaatagg tgaagtgact ccatagccag
    21001 taattaccac tcgattcatt tgtttgctct ccttttctta tccgtgcatg accaatccgc
    21061 catcgacatt gatgacttgt ccggtgatat atggattttg tgctaagaaa actgctgttt
    21121 gtgcaatatc ttctacttgt ccgaaacgct gcatcggaat ttgcttttcc gcttgttcct
    21181 tgactttgtc tgctaaaact tccgtcatat cagttgtgat gaatcctggc gcaatggcat
    21241 tacatgtaat gcctctagtt gcagcttctc gtgccacaga ttttgttaat cctactacgc
    21301 cagctttact agctgcataa tttgcttgac caatatttcc aatcaaccca gatacactag
    21361 agagattaat gatggcccct tctcgctgct tcatcatttt tttcaatacg tgctgcgtca
    21421 tattgaaggt tccaatcaaa ttgatatcca gacatttttt gaaatcttct gcatccattc
    21481 gcatcacaag tttgtcattt gtgattccgg cattgtttac taacacatgg atcgatccaa
    21541 gcttttcttc tgcttctttg atcatttgtc ccgctttctc ataatcagag atgtcaccgg
    21601 aaactcctac gcattttaca ccgaatgctt cgatttcttc tatcttttct tttggaatct
    21661 ctccgcgacc attcaaaatg atatttgctc cagcttttgc aaaagctaag gccatcgctt
    21721 tgccgattcc tcttgtacta cctgtgataa atacattttt tccttttaca tccataacgt
    21781 tcctccttat agtattgcta ttgtttcatc aaatgtctgc ttattctcaa cacgcagaac
    21841 tggtattgtt ttatcgattt ttttcataaa tccgcttaat acttttccgg ggccgacttc
    21901 gatgacttgt tcgatgccga ttgtttttaa cttatggata ctctcataga aacgaacagg
    21961 ttgcatgact tgctgttcaa gtagtcccgc gattgtttct ttcttcatta tttccgttgt
    22021 tgtgttgctt atgataggaa aagaaggttc agagaattga atctgactta ggtccttcgc
    22081 cagttttttt gctgccggtt ctaaaatagc tgtatgaaaa ggcccgctga catttagagg
    22141 gatcattctt ttgaaccctt tttcttttaa tagtaaaaca gcttcgtcta ctgctttttc
    22201 ttcgccacca atcacgatct gctgaggtgt attataattt gcaggagata cgatgccgta
    22261 cttgctagct tcatgacagc tttcctcgat cgtttcaatc ggcgcattca tcactgcaac
    22321 ca
//
LOCUS       DADGKS010000046        21993 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.046, whole genome shotgun sequence.
ACCESSION   DADGKS010000046 DADGKS010000000
VERSION     DADGKS010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21993
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.046"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            202..1167
                     /locus_tag="JXV47_001839"
     CDS             202..1167
                     /locus_tag="JXV47_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAX1487879.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGDDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(1266..2438)
                     /locus_tag="JXV47_001840"
     CDS             complement(1266..2438)
                     /locus_tag="JXV47_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1487880.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMPTIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(2425..3570)
                     /locus_tag="JXV47_001841"
     CDS             complement(2425..3570)
                     /locus_tag="JXV47_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1487881.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(3584..4508)
                     /locus_tag="JXV47_001842"
                     /pseudo
     CDS             complement(3584..4508)
                     /locus_tag="JXV47_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            4625..5704
                     /locus_tag="JXV47_001843"
     CDS             4625..5704
                     /locus_tag="JXV47_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAX1487882.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            5736..6329
                     /locus_tag="JXV47_001844"
     CDS             5736..6329
                     /locus_tag="JXV47_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1487883.1"
                     /translation="MTKSLQTILESTKEIRVLGIGHCAKDALVLYETHRPDVLLTDIR
                     MPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYLIKQNLQAIIPSV
                     KSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKEVAAGKNNKEIAD
                     ALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(6439..6666)
                     /locus_tag="JXV47_001845"
     CDS             complement(6439..6666)
                     /locus_tag="JXV47_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAX1487884.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(6769..9357)
                     /locus_tag="JXV47_001846"
     CDS             complement(6769..9357)
                     /locus_tag="JXV47_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HAX1487885.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(9377..10036)
                     /locus_tag="JXV47_001847"
     CDS             complement(9377..10036)
                     /locus_tag="JXV47_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAX1487886.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVAQHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(10085..10588)
                     /gene="trmL"
                     /locus_tag="JXV47_001848"
     CDS             complement(10085..10588)
                     /gene="trmL"
                     /locus_tag="JXV47_001848"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HAX1487887.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(10809..11675)
                     /locus_tag="JXV47_001849"
     CDS             complement(10809..11675)
                     /locus_tag="JXV47_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAX1487888.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            11784..12425
                     /locus_tag="JXV47_001850"
     CDS             11784..12425
                     /locus_tag="JXV47_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HAX1487889.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(12487..13848)
                     /gene="mgtE"
                     /locus_tag="JXV47_001851"
     CDS             complement(12487..13848)
                     /gene="mgtE"
                     /locus_tag="JXV47_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HAX1487890.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(13866..14765)
                     /locus_tag="JXV47_001852"
     CDS             complement(13866..14765)
                     /locus_tag="JXV47_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAX1487891.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(14767..15564)
                     /locus_tag="JXV47_001853"
     CDS             complement(14767..15564)
                     /locus_tag="JXV47_001853"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HAX1487892.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(15542..16246)
                     /locus_tag="JXV47_001854"
     CDS             complement(15542..16246)
                     /locus_tag="JXV47_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HAX1487893.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            16377..16952
                     /locus_tag="JXV47_001855"
     CDS             16377..16952
                     /locus_tag="JXV47_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HAX1487894.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            17070..17747
                     /locus_tag="JXV47_001856"
     CDS             17070..17747
                     /locus_tag="JXV47_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAX1487895.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
     gene            complement(17826..19634)
                     /gene="pepF"
                     /locus_tag="JXV47_001857"
     CDS             complement(17826..19634)
                     /gene="pepF"
                     /locus_tag="JXV47_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HAX1487896.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSDAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(19810..20808)
                     /locus_tag="JXV47_001858"
     CDS             complement(19810..20808)
                     /locus_tag="JXV47_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HAX1487897.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(21034..21687)
                     /locus_tag="JXV47_001859"
     CDS             complement(21034..21687)
                     /locus_tag="JXV47_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HAX1487898.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
BASE COUNT         6492 a         4699 c         3814 g         6988 t
ORIGIN      
        1 cttttttgtg tttttcggtc ttcggacctt tttcattttc ctagacttct gctataataa
       61 ccaagaatta attttgtaac agattttttt gaaaaaacaa gtttctttca ttcaaaaaat
      121 agaaaaagct tgctaattat tggttaacca gcaaacagga gtattaaaat atcttgtttt
      181 attgaatagc aggaggaaat catgaaattc cattatcata tattgatcaa tccatcggca
      241 ggcagcggaa atggctataa agtagcagaa agaattttac cggtattaaa aaataagcat
      301 attgactata cacttcatta tagtgaatac aaaggacacg atgctgagat tgctgaaact
      361 ttggcaaaag aaacattgat tccttggata gaagaagaac agaaaacaat cgatactttc
      421 ccccttttga tcatcgtagg aggtgacggc accttacatc aggtacttga tactttctat
      481 cagatggaag tagaattccc agttgcttat attccagcag gttctggaga tgattttgct
      541 cgaggggcag gccttccaaa aaatcccaaa aaaggacttc agctgatttt agcagctcaa
      601 tcaccagaaa aagtccacat aatggcttat gaagaaaaaa taagtgaaaa aaaaggaata
      661 gctgttaata atttcggtat aggattagat gcagctatcg tccatgcgac aaatcattct
      721 tccacaaaaa agcgattgaa caaatacaac ttaggatcat tttcgtattt attctctatt
      781 ctccgtgctt tattcactca aaaaggattt ccaattctgg tagatgcagg aggaaaacaa
      841 ttaagttttt caaacgcatt tttatgtaca gcaacgaagc atcctttttt tggcggagga
      901 atcgcgattg ttccaactgc tgatgcgtct aaaccagtca ttgattttgt cgtggtcgaa
      961 cgaatcaatt tctttaaaat cttgtggctc attcttttac ttatacagaa aaaacaattg
     1021 aaatcgaaat atttccatca ctacacaaca aacagattac gtatcgtttc aacaacaccg
     1081 caacatggtc aagaagatgg agaagaaatg gaaaaacgac cttttgatat cacaataacc
     1141 acaactaaac agttgttttg gtgttaataa aagaggtttt gtcagaagct acatctggaa
     1201 caccgtttat tcggaaaaaa ggactgtgac acgacttttg tcacagtcct ttttttacta
     1261 tgcagttaat tctttgccca attgggttgc catcgatagt ttctttcttt acccaaaata
     1321 aattggatca ttgaaaacac cgcagcaaaa gcaactaaga cacaaccatt gaaccaaaaa
     1381 gattctgcaa atgtttgatt gtaactgagt gtttcactga tcaagttatt attttgaaca
     1441 aaccaatatg ttggtgtgaa tgccgctatt ttgctaacca tttctggcaa gtattctgct
     1501 ggtacaaaca ccccaccgat aaagcaactg cctgtgataa aaatatcttt gatcccaccg
     1561 ctggtttctg agttttttac caatgaagtg atacaagccg aaaagctaat gatcggcaat
     1621 aaaaacaaga aagtatttaa aatatgatac cataccgtta tatcccacga ggtgtggatc
     1681 actaacagaa ccattagaag taagaagcca ctgaacaaca gcagcgagta actaatcaaa
     1741 ctaaaggtta ctttgcgatt caagtttcgt ttggtaatgg gcgcactctg gtttcgttta
     1801 ctgatctctt tgcgattaaa tgctagattg atgacgctga aaccgctaaa aatggataga
     1861 aacaacccat aagacaagaa attaaaggtt gtgcccgtca acagcttttt catccgctga
     1921 ctatatcccg cacttagctc aacttctcca gtaaccgaga gtgccatttg tgtctgttcc
     1981 atagctgcat cgattgtttt atcttcttct tgaaacagaa tcagtgtttg caaaaaggtg
     2041 ttcacttgct gtgtaacaac tgttttagaa aaggcatctg ggcgactctg tatcttgatc
     2101 gtcggcatct ttcctacttc gacttgttcg gtaaagtctg caggcagatg taagataatg
     2161 tttacacgat taaaataaag agcatcatcg atttcttttt gtgaggttcc atccaatgta
     2221 acgactgttt ccttgtcatt caaatattta cgaaggccat cgactacagg cgactcttct
     2281 tcactaatca aggcgatttt cgcatcttgc agagaggtat tttcaacatc aatattttgc
     2341 gcaaaaaaga atgtggcaac aacagtgata attacaccta tcagtaaatt cgatttattt
     2401 gctttaagca atgtccaaat cgttttataa agcgtcataa cgcacccctc tttccatcca
     2461 agcatttcct aacgcaaaaa ggaaaataaa tccgatcaac catagaagat tggtataaaa
     2521 actagccaaa tcagtgtaga aataaagttt atacaaactt tcgctgatca agttgacgag
     2581 atttaattga ccaacaatcg gaatatgaag atcaatccaa tacttcactt gttccgaccc
     2641 catcatacca gcaaaaaagc tcatcgcaat cgtcactgaa atcaagatgc tatccttttg
     2701 caccagattc atttttggta tcaaattacc aaccaatgta cctaacaaaa tcgcacacaa
     2761 cgaccccaga gcggtaacaa tcatcaacca ttgccaacgt tcaccaaagt ctacttgata
     2821 gataaaacga aagacagcta acataatata aatctctgtc aaaacaatcg taaagcttgc
     2881 tgccaaatta gcgattgaaa ctaacgattg ctttctagga atcaaggaca agcgaatacc
     2941 atttgacgat tgatttgctt gctgatcctg tacattgcgg accccccaca tcgtcccgta
     3001 gagaatcgcc attccaatca gagtgaagaa ataaaaactt ttgaaactca tattacgacc
     3061 tgcatgaact tcttgaaaag atacttcttg ttcaaaaaca gtcatgatgg gcgcgagatc
     3121 aacgttctcc acttctgcca ctttactcga aattatacca atacgctgta aaaattgatc
     3181 catgacgttt ttcatcaacg tctgactcat tcctgcttga cccacatgga gcgaaacaga
     3241 tgaaccatca atgagataaa aaccagccaa atcatctgca tttagctttt cattcgcttc
     3301 tacttccgat agttcctgta cttcaaataa tggtttatca ttgacttcga cttgttctaa
     3361 gactgtggta aaattttccg aaagcgctgt ttgatccgct ttgattacaa ttccagtatt
     3421 aatcgtttcg agattgccac cttgatcaat ctcgccaaag gccgccataa acatcaatcc
     3481 taaaagaatt ggaaaggcca atgtccaaaa caacatggat ttatttcgca gcagtatttt
     3541 tgtgcgatat ttataaaaat gccaaaacat tatttcccct cctctagtct ctcaaatcct
     3601 tgccagtaat ctctaaaaag acatcattca aggacgcttc tttggttgct atttttccgt
     3661 aactgatctt ttcttcttgt aagattgtaa gaatcggcaa caatactgta tttagttcag
     3721 tagttgttac ttggagctga ccttttttat aagcgattcc atcagaagct attgttcgct
     3781 gacaacacgt tttctgggag taatgggatg tcgatcgtca aacgatccgc cgtccgtacc
     3841 atatctttta gagattcttt ggttccttta gcaatcacct gtccttgatc catgatcacg
     3901 atctggtcgc aaagaatttc tacttcttcc atgtaatgtg ttgtatagac aatggttgct
     3961 ccttgtcgat tcagctcctt gatactttct aaaattttat tccgactttg ggggtctaca
     4021 gctactgtcg gctcatctaa aaaaattaac cgcggcttgt gggcaatccc acatgcgatg
     4081 ttcaaccgac gtttcaagcc accactaagt tctcctggac gaaacgaaac atatttttct
     4141 aatcccacta attgaatcac ctcttcaatc aaggctttcc ttttctcttt ttcggaaaca
     4201 tataaaccgc aaaaataatc gatattttct tgcacactta gttcgtcaaa gaccgcaacg
     4261 tcttgaggaa cgaccccaat cattgccttg acagcataat tttcaggagt cattgttgtc
     4321 ccgaacaatt taatggttcc tttgtcataa tttaacaaag aaagcataca gttgatggca
     4381 gtcgatttcc cactgccgtt tggtcctaac agacctaaga cttctccttc ttgtacttgc
     4441 agatcaaaat gattcaatgc tacaaaatct ccatagcgtt tgactaattt atcaatttcg
     4501 ataatcatca tgaaaaactc cttccaaatt tcttgttgat ctgactataa taaagtgcaa
     4561 gaaaagaaac tagtgacgat tggctaaacc acacatgaca tttgtcacaa tgaaggagtc
     4621 tgctatgcat aaatctcggc tactcaacga aactagcttt ctactggtta tctcattgct
     4681 tttgctggta agtcaaggat tcgttgctat gcaagttatc tatttattga tcgccgtttt
     4741 attcactggt gtcagttatt tactgcctac aaagccaaat tggattttcc aagttattct
     4801 atttctttta tgtgcctttt tacctgatct tgtcctgttt ctgccagcga cgatgcgagt
     4861 gatcgcccct gaagaaagcc accttgatta cttgtttttg ttaggttttt tgttgatttc
     4921 gacggttggt aatcatcccc ccatcaaggt cgcctttgtc gtaattttgc tgtttttttc
     4981 cttttactta cgaaaaaaag atcaacgaac gaccgatctt gagaaaaagt acattgtctc
     5041 caaagatact cattgggaaa aacaacaaga gttatcggaa caaaataaag cattggccct
     5101 gtcacaagaa acacaattag ccttgcaaat tgtggaagaa cggaaccgaa ttgcccgaga
     5161 catccatgac aatgtcggtc atctgctgtc aagtgcgatt ttacaaattg gtgcgcttga
     5221 aatgatcaat caagaaccaa aactaaaaga accattagaa aatttaagtg ccaccgttca
     5281 cactgggatg gatcggattc gtcaaagtgt ccatgacctc catgagacat cgatctcttt
     5341 tcaacactcc ttagagtttc tgatcgctga ttttccttct tctgttacga ttgaaggaaa
     5401 cttgtttgaa ggattgaatg aaacgcagca aaactgcttc ttaatggtca tcaaagaagc
     5461 cttaaccaac agtatcaaac atagtcatgc caaaaccgtt gttttacatt ttcgaacgtt
     5521 gccggccttt tatcgcttgc aaatcacgaa tgatggcacc agcccacaaa aaaattctgc
     5581 tcccggtatt ggtttgaaaa cgatgcgtca acgtgttcaa gaacaaaagg gacaagtcca
     5641 tattttccaa gaaaaccagc aatttcagtt aacgatcatt ttaccaaggg agggacacca
     5701 atgataacag tagtcattat tgagatgatc catttgtgac gaaatcgtta caaaccattt
     5761 tagaaagcac gaaagagatc cgtgtgttag gcattggtca ttgtgccaag gatgcgctag
     5821 tcttatacga aacccatcgt cccgatgttt tgctgacgga catccgcatg cctaaacaaa
     5881 cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc caaagccatc cttttgcttt
     5941 tgacgacatt caaagatgaa gaatacatcc gcgaagcatt ttccatcggt gtcaaagggt
     6001 atttaatcaa acagaacttg caagcgatta ttccttctgt caaatccgct tataatggac
     6061 aggccgtatt tggtaatgaa atcatcgaga ctttcactca aatgatgaag aataaaccga
     6121 cgattgatag tcatgcttat gcttctttta gtgaacgtga gcttgcaatc atcaaagaag
     6181 tagctgccgg gaaaaacaat aaagaaattg cagatgcctt gtacttgagt gacggcactg
     6241 ttcgcaatta catcagccaa ttactagaaa agctagattt acgggatcgc acgcaattgg
     6301 ctatctattt ttatcagcat ttgcaataag tcttatctaa cacaaaaaaa cctgaatgat
     6361 gctccttcgc atcattcagg tttttttcac atcttctatt caattgtccc gcaaaccatt
     6421 tcctcacgat tgaaagaatc aaggattcgc agggctgcca ggattcgttg gattgttcgg
     6481 cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt tctagttttg attcttcacg
     6541 atcgtctcgt tctacatcag gactttcatt caatttgaat tctttttcca tctcatctaa
     6601 ctttttaaag tcattgccag attcttttgc taatttcgct aatttatctt cggtttcttt
     6661 agccataaag taacgccccc cttttgattt cagcttagca tatcacactg aaaaaacaaa
     6721 agaaaacgct aaccaacgat catttttagc tatttctcat ctttaaaatc aagcattttt
     6781 tgccggtata aaatcgtagg gagaactgtt ttccatacca atcatcggat ctactaactg
     6841 gttatcgatc acttctgctg taagaacgaa atctttagaa acagcaggtt ctacctcttc
     6901 tttcttttct tctccaacaa atgaagaaaa cagatctggt tccactgttt ccattacttg
     6961 gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt agcttttctt ttacaacccg
     7021 tggctctttt gtatagttcc catcttcaaa tggatcattt ccgaccaaag aatcttcata
     7081 agctgctagt ttggtccgga gagtgatatt cattttatca ttatccatga tccttgattt
     7141 caacgtagtc atccggcttg ctgattcatt cgctacacaa gtgacatagg cttgctcttc
     7201 ccctaacaaa atcaacagtt ccttactgcg agtcactgcc gtgtagagca aattacgctg
     7261 aagcatccgc tgatattgat ggaccatggg caaaataacc atcttgaatt cactgccttg
     7321 tgatttatgg attgagcaac aataagaaag agtgatttta ttccattcgt ttcttttata
     7381 agtgacctca tttgcatcaa actggataac taattcatcc actttatctt cagaatcttt
     7441 tgccaagatg atacccgtga tttctcccat atctccattg aatacattca attcgggagt
     7501 attgactaat tggaggactt tgtctcctat ccgataaacg gtgtcgttcc aatgtacttc
     7561 cttttttcca ggtttccctg gattgaatat ctcctgcatc attttattta acgcatcgat
     7621 ccctgcaggt ccccgataca ttggtgctaa tacttggata tcttgtgcac ggaatccctt
     7681 atttttcgct ttttccacaa ttttagagat caagggttca atttgataag catcacttcg
     7741 gaaataggaa cgatcttttt gattctttgt gaaatctttt ggcagacgtc cttctttgat
     7801 ctcatgggca agaggaataa tactagaacc atcaccttgc cgataaatct gattgagttc
     7861 cattttggga atttgttcga tttccaaaag atcatggagt acttgaccag gaccgacaga
     7921 gggaagctga tctttgtctc ctactaagat aacttgcata ttcgtcggaa tcgctttgaa
     7981 taatgtgtta gccagccatg tatcgaccat agacatctca tcaacaatca aaagtccgcc
     8041 ttctaattct ttcgtactga ctgaaggtgt tttttcccgt ccattcagcc ccagaagacg
     8101 atggatcgta ctggcaggca gacctgtcgt ttcgttcatt cgtttagctg ctcggccagt
     8161 tggtgctgca agtagaatag gaaaaatttc ttgggtatat tttgaaggat ccaattccag
     8221 tccgttcaac tctgcaaaaa gattgacgat tccgttgatc acagtagttt tccccgtacc
     8281 tggtcctcct gttaaaataa atagagggga acggattgct tcagcgatag cttgttcttg
     8341 cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc cgaatattct tctgcacttc
     8401 tttttcagga taatggattt cttttttacg actgagaagg cgctggatcg aattaccgat
     8461 cccccattca gaaaagtaca aactgttttc gtaaagatta gtctcttctt gttgtatctt
     8521 tccttcttca acaagttgga taattacagt agcaacctga tcaggctgga tttcaattgg
     8581 gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat gtctccgccg gtacgtatgt
     8641 atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag atagctgctc gaattcttct
     8701 cggtgaatct gctgcaatac cgatttgttc ggctagatta tctgcacgtt tgaacccgat
     8761 tccttctatg tcttcgacta gctggtacgg attttcttcg atgatatcca aagactcgtt
     8821 cttataggcc tggtagatac tgaaagctaa ctgactaccg aacccgtaac gattcagtcc
     8881 catgatcact tgatccatcc cgtggtttag ccgaatcgtc tcagcaagca tttctctttt
     8941 tggcttcgtc aaaccggaga tttgttttaa taccgaagga tcagcaatga ttttttcgat
     9001 agcatcttct cccagcaatt ctacaatttt ttctgctgtt ttcttcccga ttcctgggaa
     9061 tttttcgctg gaaagatacg ctacgatccc atttgcagtt gttggctttt cttgctcata
     9121 tctttcgagt ttaagctgcc ttccgtattt aggatgatcc actaattctc cataaaaacg
     9181 ataagtctca ttttcttgaa tatcgccgaa acttccggtg actacaatct ctttttcacg
     9241 gtaatcagct gtggtttcac tgatgtgtac caaaagcact ttgtaaaaat tactaggatt
     9301 ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc atttcttctg gctgcatcgg
     9361 aagccgcctc cttcttctat agtaaaggtt ctggtgctgt ttcagttcct aaaaaatctg
     9421 tttggttcca tactttcagt tcatatggca ataatctgca aggctcttca gtctctaaaa
     9481 tcgtcaaact actattgaac aatccaccca tttcacgcaa ctcacttagc tcttttcctg
     9541 tcatccattg aatggctgca gttaaagaag ctccatgtcc tacgaataaa agtgggccat
     9601 ctttatgttg ggcaaccgca tctgctacaa cagtttcgat acgtgtgatt gccgattcaa
     9661 tcgtttctcc gtgaaaagga gaaggatcat acagatctaa atgattacgc aaattcggca
     9721 gattatccgg atatttctgg tacatttcat cgatcgactg accttctaaa gtacccagcc
     9781 ctagttctct tagcttatct gtataaaaaa tctctaccgg acgagcaagc tctttgttga
     9841 taccttctgc tgtatcacgt gctcgctttg ctgtactgga ataaattgct ttaaaaggaa
     9901 catattttac ctttttccca aatgctttga tttcttcgta actttgtggc aaaagcggag
     9961 aatcgccatt gctcccttga aaacgtcttt cctgattcca ttgtgtcttc ccatgtcggg
    10021 taaaatatag ttccatacgc agcaaactcc tgtctttctt ttattttact ctataataaa
    10081 ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa ttctaaatta gggaatcctt
    10141 gctggcgaag tgcttcatac actatcattg cagctgtatt cgataaattc aatgagcgga
    10201 catgctcatc attcataggg atgcgtaaac acttttcttc gttttcacgc ataaatgttt
    10261 ctggcaaacc ggttgtttct tttccaaata aaaagaagtg ctcttctcca tcagcaaaat
    10321 tttcgtcact atatacttta tgggcaaatt ttgagatcaa atgtagttta cgattaccta
    10381 aaaatgttaa aaaagcttct aaattactgt ggtaagtaat atttacatca ttccaataat
    10441 ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa acctagtggc tcgattaaat
    10501 gaagcggagt attcgtggct gcacacgtac gggcaatatt tccagtgttt gcagggatta
    10561 atggttcaaa taaaacgata tgattcatca ggatcattcc tctcatattt atgttcgttt
    10621 ctattttctg acaatttgat ttttgcataa aaaaaaacgt atcaactcgg tgtcagtcac
    10681 tgcgagtcgt tacgttagtg aagctcttct cactaacttt tatcagaaca ggaacctgat
    10741 aaaaaccaat gaaaaaacaa cttgttgcta atataacacc ctcaactttt ttttgcaacc
    10801 tctactcatt aaaaactgct agaaaaacgt tttctcttag ttccttttaa taattctatg
    10861 tcaattgtaa tcttcttcaa aggattctta tataagtctg ctttgattcg ctcttctacc
    10921 tgccattcta aaggtgacat ggccaaaaga tctttttgat tttcctctgg tatctcaaat
    10981 tcataggtta cacgctgacg ttcagttaat ttcattgctt cagcaaactt ggctactaca
    11041 cgttcattgg aataactctg tttttcaggt tgattcggat aaaaagcctg acgtagttcc
    11101 tttaaataat tttcttgtgg caccaccttc aacacttctc catcttctga gagtacacgt
    11161 tggaattctt ggtaatgaga aggcgaaaag atatttaaaa ccgcgttgaa tgtttgatca
    11221 gcaaacggca aattggtcaa atcagctaca caccaaaatg cttcggcaga ttgttctgta
    11281 gctgcgtaga ctccttcttt tgaaatatca aatccaacag cattttgaat ctttttcaat
    11341 tttgaaagtt cattcaagaa gctaccttct ccgcagccaa catctaatag cgagacttct
    11401 tcaggtaaat gctgcgcaat agtctcaata acgggctgat acatgccaga ttggatcatt
    11461 ctacgccttg gaacgaacat tccttgatcg tattctgttt taaccgcatg ggataaaaaa
    11521 taaagtgttc cttttttgga aaggtcaaaa cggtgattat ttttgcatat caagccatta
    11581 tcagactttt ttacttcttc ttggcaaacc ggacagcgga acagctgatg attttctgcc
    11641 aaaaactggc gtcctcggtc aatttttttt aacatagttc cccctcattt ctgttttatc
    11701 ttaccgttag atgctcactt tggcaactgc taaaaatatg atacaatgcc tagaagaaag
    11761 tgaaagataa aggagaagat tagatgatca aagaattttg cgctgaaaac tacacatcta
    11821 ttcctctagc aattgctaga ggagccgatc ggatcgaatt gtgtgacaac ttagcggtcg
    11881 gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt aagttatgct ggggaaaaag
    11941 atatccccgt aatgacgatt attcgtccta gagggggcga cttcgtctat aacgatatcg
    12001 aattgaaaat catgcatact gatttgattg aagcaaagaa attagggacg gatggcgtag
    12061 tatttggttg tcttactcct tcaggctggc tagacgaaga ggccttagaa ctattgatcg
    12121 aaacagcaga agggttgcag atcaccttcc atatggcttt tgacagtatt cctgaagatc
    12181 ggcaattcga agcaatcgat tggctggtag aacatggtgt tgaccgtatc ttgactcatg
    12241 gcggtcctgc tgacaaaact attgtagaaa atttcccacg gcttaaagaa ttgattgcct
    12301 atacagatgg ccgcttaatc attttgcctg gtggtggtgt cactgcagag aatgcagcac
    12361 atgtagctaa agaattgaac gtaagcgaag tacacggaac caaaatcgtg gatcttcagt
    12421 tataatctta taaacaaaaa aacatttgca acaggcataa tgcttattgc aaatgttttt
    12481 gtttttttac ataaaatagc ccataaataa agaagcaata ttgaaataaa tcagtacact
    12541 cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct actgctggat caaatcctag
    12601 acgatccatt agcatcggga ttaaactacc tgcaagattc gccactgtga ttgcaaatag
    12661 catagccatc cctatgacaa accccaagat aaaattatgt ttccaaaaac ctacgattag
    12721 aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg gtcaagactt cagccaaaac
    12781 aagtcgaaca aatccatgat ctttctcatc agaaatcgca agtcgacgaa cagccacagc
    12841 tagcgactgg gttccagcat taccggcagt tcctgtaatc agcgaaatga agactgctaa
    12901 aatactcgct tcacttacca agtcttcata gtgactgatt aaagaagcgg tcgacatacc
    12961 taaaaacaac agagtgatca gccaaggcaa acgtcgagac gctgccttta ctggattttc
    13021 attaatttct tccacattga ccccggcaag tcctgaataa tcgctagcag cttcatcatc
    13081 aataacgtcg atgatatcat cgactgtgac gattcctaac aaatgatcat cataatcggt
    13141 aacaggaaga gctaagaagt cataatctct aaatgtttgt gccacatctt cttggtcgtc
    13201 gcctacatga actgaaagca ctcgttcgct catcagatca gaaatcattg cgtcgtcatc
    13261 attcacgatt aggtcgcgca gagaaataac ccctactagc tgaccttctt gattaacgac
    13321 atagatgtaa tagattgttt cagctacatc tgcttcgttc ttcagcacgt acatcgcaga
    13381 gcgaacagtt tgattggcta cgatcgaaac aaattcagtt gtcatgatcg cgccagccgt
    13441 ttcatcctcg taatggagaa gttccttgat ttcactggca tcgtctgccg acatcaaact
    13501 taaatattta gcaatttgct ttttatccag cgtattaagc aagtcaacag cattatctgt
    13561 atacatctca gaaagcatat cagctgcata gctaggacgc atttcatcta ggtattcttt
    13621 catatgttcg ttgtcttctt caatcacatc gaacatatcc gctaattctt taggcgacag
    13681 ataggaatag atcagctgcc tgttctcttc tgtaagagat tggtagaatt gcccctgctc
    13741 atagatatgc atctctaaaa aactgtttct gaatgcctga atattatttt cccttaaatc
    13801 ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt tcatccaaac caatctcacc
    13861 tcgccttatt cttcaaaccg tctcacaact gcctccatgt ctgcggctaa aggctgcttg
    13921 aactccagca actcttctgt aaatggatgg taaaaacgca gatcataaca atgaagggct
    13981 tgtcttttta ttcccagatc cattcgcccg ccatacatat catcaccgag cagggcacag
    14041 ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc ctgtatgcag ctggatatca
    14101 actaacgcga tttctgttag tcgcttctct atccagtact cagtctgtgc cgaacgtcct
    14161 tcatcagaga ccattcgctt caatagcgaa gaataatctc gggcgatcgg caaatcgata
    14221 tgtccatgtg ccgataaatc tgaaagcctt ccactgacta aggcctgata ttttttcaca
    14281 aacttctttt cacgaagttg catatctaat tttgcgtgcg caaatccatg ctttgcaaaa
    14341 agcatcaaac cagatgtatc ccgatctagt cgcgtcacca catggattac ttggttttcg
    14401 taaccttgtt ttttataata agcctttaca cgattagcca ttgtcccatt tggatggtat
    14461 tgggcaggaa tagacgaaac gcctgctggt ttatttacta ccagaacgtg ttcatcttca
    14521 tacacgatat cgatcggtgt ttcatccaaa agtacggttt catgttctcc ttcagcagga
    14581 atcacaatgg ttaccttatc atccttagct agagaaaaca agacattttc tacttgatca
    14641 ttaactttga tttgaccgcc ttgaaatttt attttcgcta acagaccctt tgagatccct
    14701 ttttctttta aaaaatattt tacttgctga gaatgatctt tctcataatc ccatgtaaac
    14761 tgcatatcaa tcctcactaa taaaggcatc tttcacacga tgccaaaaat gcatatgtcg
    14821 ataagaagca aaatggatcc gttcttctgc tattcgataa taaattgagc ggatatttgc
    14881 ttttgcgaca ttcaattgat caaccgttac aagataatct tctgtatttt ccaattttat
    14941 ttctagccat tcatcatggg caatcacgat cggagaaccc aaagtacgaa acactcgatt
    15001 attcagtgaa gcaatctctg ccaactgaaa ggcattgata ctaggatgga tcacagcacc
    15061 gccgacactt ttattatatg ctgtcgaacc agtaggcgta gaaatcgtca atccatctcc
    15121 tctaaaactt tcaaacagct cgtttttgat gtatacatcg gctaccatcg tacgattggc
    15181 ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg tccggtgttt catccaaata
    15241 actgatccga acatccagca agggataact aacactttgt tcccggttcg ttcgtaagct
    15301 gtctactagt tcttccagct cgtaatcccg ccaatccgtg taaaacccta aatgacctgt
    15361 atgcacgccc aagaaacgca catcattcag acaatgactg tagtgatgga acgccgacaa
    15421 taatgtgccg tctccgccga ctgagatgac caattctggc tcatgatcat ctcgttgaat
    15481 ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact tctatagtct ttgcttcttt
    15541 attatgaacg atcgctactt tcatcccctg cctcctctct ttcgctttct ttcttcaaaa
    15601 gcgttcgata gtagacatca tctgattttc ctcttccatg ggagaataac cgctgtgctt
    15661 cttggatttc ttcacggata ctggacatct cttcatccaa ctgataggca gcttctgccg
    15721 cacgctgaag tcgttcactc atttcttctg gaaaaacgcc ttgatattta taattcagcg
    15781 aatgctcaat cgttgcccag aaattcatcg caagagtccg aatctggatt tccgccaaaa
    15841 ttttcttctc accgctgatc agctgtacag gatactcgat caccagatga taagaacggt
    15901 agccacttgc ttttttattt gtgatgtaat ctcgttcttg gagaactttc atgtcttttc
    15961 ttttacggat gatctcaaca acttgatgga tatcttctac aaactgacac atgatcctta
    16021 acccggcaat atcagacatt tcttcttcta aacgtcccat tggaatatgc cgtaattgtg
    16081 attttgttac aatactatcg actggcttga ctctcccagt gacaaattca atcgggacat
    16141 gtcgattttg ttcacggaac tgtttgcgga tcccccgcag tttcactttc aattctgata
    16201 cagtttgttc atatggtgct aaaaatgctt cccaatctcg ttccatagct gatacctcta
    16261 cttcattaac attcattgtt tattctacca tatatgcaaa gttttttcgt actcttgatt
    16321 tatgcattga ccaaaaaaag aaaattaggc aaaatagaca aaaaggagtc gatcaaatga
    16381 cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa gcaagagtac gagatattca
    16441 tcgctcacta tcaattaaca gataaagatt tccgtgtaca gactaatatt tatttcgata
    16501 ccgttgatga acagctgaag aaacaaaatt gtggcctacg gatccgtttc gttggtcatc
    16561 aagctgaata tacattaaaa acacctgctg aaaaagggcg tctcgaaaca acggatacct
    16621 ttataacaga agaagcagaa gcatttatct tcgaaaaacg tctgcctcgt tcaggcgcag
    16681 tttttcaaaa actttctgat ttgaatatcg atcctgcttc attaatccaa accggaaagc
    16741 ttacaacaaa acgggctgaa ttccctattg aagaaggact tttagctatt gatgaaagct
    16801 ggggagacaa tctacacgat tttgaactgg aactagaggt aggggatgca tctgtgggaa
    16861 aaattgcttt tataaatttt ttaaaacgtt tttctttacc ttatcgtcct gctaagaaca
    16921 agatccaacg tatgcttgaa gctaaaaatt agaaaccttt cattttcaca aggcacttga
    16981 gttcattttt ttactttttt ctgttaagtt ataggatgtg aaagaatcta gtcactagtt
    17041 gtatagaatc tattttgggg gagattcata tgatcgaaat ctatttattt gttaatcctt
    17101 taggggaata ctgtttcgaa atggaacaac agttattaca atttatcgaa gaagagtacg
    17161 ggacaccatc aaaagaaaag atgcaatttc gctttcttcc tttggtcaat ttgcagacaa
    17221 ttggggatgt catgcaacaa aaaggaattt ctcagaacaa tcttgaggaa cgtaatcact
    17281 tattctcaat gacttattct gcagcattgg actgcaaagc ggcgcagttt caaggaaaga
    17341 aaaaaggccg ccgttttttg atcaaattgc aagaagcagt cggctgtaat gacataccat
    17401 attctcaaga acttgctgaa tccatatttg aagaaatcgg cggcgatttg aatatgttta
    17461 aagaagatcg tcagtctgac ttcgttaaag aagtattctt ttctgatcaa aaaattgctc
    17521 gggaaatggg catcacaaaa cacccttctg cagtcgttta caattatgcc tgcgaccgtg
    17581 attttggtgt tttagtagaa gtaaaaggta caagtagcct ttggagaatc acagagctgt
    17641 gtaaaacaac agataactca tatcaagttt ttaatggtga acatttacat acaaatgatt
    17701 ctcagttcca ttcaagaact agccatttac acttgctttc taattaaaaa aatacgtcga
    17761 ctcccttaca agagagccga cgtatttttt tcgtttctat tcgagaaaat caaaaataga
    17821 aagccttata aacgatcgat caattcttct aattcattta gacgttgttc aaacatcgac
    17881 attgcatctt caatatatgc agcctgtgtc atatcaactc ctgctttttt cattacttcc
    17941 acaggataat cgctgttacc tgcttttagg taagccaagt agttctctag tgcctctggt
    18001 tcctggttta gtattttctt cgccagtgct gaagcagcag aaaagccagt cgagtattgg
    18061 aaaacatagt aattataata aaaatgcggt atccgtgacc attcgaattt aatttctggg
    18121 tcttcttcga ctgctggacc ataatatttt gcattcaatt taccataact atcacttagg
    18181 tattcactag tcaatggcac acctttttca tcttccgtat gcatgaaatg ctcgaattca
    18241 gcgaattgtg tctggcggaa aactgttcct ttaaacccat ccaagtaatg gttgagtaca
    18301 taagcccgta cacgagggtc tttttctgtt tccaataaat actccgttag gatattttca
    18361 ttcgttgtcg aagcaatttc tgctaaaaag atggagtagt cgccgtacac ataaggctgg
    18421 ttcgaacgag tgaaataact atgaacacta tgtcccattt cgtggacaag cgtaaatagc
    18481 tgatccagcg tatcatgcca attcaataaa atatatggat ttgtgtcata gcttcccgaa
    18541 gaataagcat cgcttcgttt ccctttattt tcgacaacat cgatccaacg ttcagagaat
    18601 gctttttcta cgatggccat gtattcttca cccattggtt tcagtgcttc taaagctttt
    18661 tcttttgctt cttcgtacgt aaaggtaatt ggagcttccc ctaagaccgg tgtataaaga
    18721 tcatacatgt gcagtttttc cacttctaat aaacgtttcc gtaattccat gtatcgatgt
    18781 aacaaaggca aatgcttgtt taccacgtct accaaagtat cgtatacact ttcaggaata
    18841 tgattattgc tcaaagacgc ttctctggca gagctgtaat tacggacttt cgctttaaaa
    18901 ttatgtcctt ttatatgtgt gcctaaagta gaagcaaatg tatttctaaa ttgttcgtaa
    18961 acactgtaca atcccttaaa tgctgcttcg cgcacccttc gatccgtgct ttctagcaac
    19021 tgaccataca cgccatgaga taattggact atttcaccat tttctccttc aatcgttgga
    19081 aaaactagat ctgcattatt caaaacagca aatgtatcac ttgaagcatc aaagatttca
    19141 cctgctccag caagaagaga ttcctgctca gcagataaga catgggctcg attatctact
    19201 atttgctgga tataatggcg atagacttcc aattttggtt cttctttgaa atattgccaa
    19261 atctggtcat ctgacaattg caatatttct ggttcaaacc aggaaacggc ttcactaact
    19321 ttcgaaaaca gactgcttgc tcttgcataa agcgcttggt aatctgtatt tccagtgtct
    19381 tgatcgtttt taaggtgcgc atatacataa atgacttcag tttggcgata aaccctcaat
    19441 acgaattcaa tcgcatttaa aaattgagaa gcgccttgat caagtgttcc tttgtgtttt
    19501 tcagattgtt ttaactcttc tgataattcc aaatatttct catcaaactc ttggtcgctt
    19561 gaaaagatct tggtcaagtc ccaagttaaa ttttcaggca attcttctcg ttttggcaac
    19621 tgctttactt ccatgaaatc cactcctttt cttcccttag ctctatctat caaaatagat
    19681 catagtctaa catccacatg tcacagcatc taacttttct actcattcat gtgtctgctt
    19741 ccatcaattt tagcataact aaatcttgtt ttacatagaa aaccgattcc tagcctattt
    19801 ttatacttac tattttttca aagaagacaa gtgtatgcat tcgttaaaaa actgctgata
    19861 gaccatctct tcatcaatca taggaaaaag ccattccctt ttatgttctt ttatttggca
    19921 aagccatgag ttgaaatcag gaactttctg gttttccaag gcttcttcgt acaacattcg
    19981 ataaagaaaa acctgttctt gtaaataaaa gaaaaaccga cttttttgat agatccacga
    20041 tgatagatgc aaaagatgtt tatgacgcaa gtagcattgt tcttgtatgg atactgtatt
    20101 cttttgcttg tgaataagtt ggcgtgtcag ccatttcttc ccatcttcac tcactttttc
    20161 tatttttttc atttggttca ttttaatttc gttactagtg aatatttctt taaggtccct
    20221 actagaaaaa gtccagcagc tactgcaaaa ggaaatatgc cctgatacag tctctgtaat
    20281 atgatgatac aaataaagct tttgtttctt gagatcagct ttccagcaat gcactcctct
    20341 ttttctatta tagtagcagc aacttttttc tatcaatgag aattgcgatt gtccaagaaa
    20401 agaattacca agtatccacc atacttggta actgttattc aaataatttt gggttctttc
    20461 aataaatctc tggtgagaca gtctagaaca ttggatttct attgctagat tcgccaacaa
    20521 aatatccggc ctttgccgca acctcggcaa ataggcttcc aaaaatactg gttctactga
    20581 ctgtcccagc caatccatga agcattcctt taactgtaag tgctcttttg attctctttc
    20641 actaaagacc gaacagttat ctgatttttg atgggcaaaa tgagcacatt ttttctttcc
    20701 ctttttcaaa atcactcttt ttcgacagcc acgacaataa tatttctttc ctttttctgc
    20761 atgtttagca aaacagcact tattatattc attcattgca agcagcattt ttctccctct
    20821 gaacttattt acgtctaaga atttatttac acgaaaaaag agggcgtgaa aaagctattc
    20881 tgcatcaagt aataagaaca gctaaacaaa aatagttccc aatatttttc gtttggttgg
    20941 gcttgttacc gcagatgcaa gcttttgaac acatttatac gaaaaaaaga ctgcgacaca
    21001 atttttgtca cagtctctta ctataatgct gatttataca aaataaaatt tcgttcgctc
    21061 gatagcatta cgcgccatca gacattgtcc atattcattc aatgtttctg gtgtacgatc
    21121 gctcttttca gcaaactcca aaattcgagc aatctgattc tctacatccg cttggttgag
    21181 attttccatc cagaagtgaa cgactaggta atagcgctct tcgaataaat acaaatcagt
    21241 ccaagcagac tctagttcga catctgttgc aagttggatc acttgttcaa aatcttcaaa
    21301 agcaaaagtt gcttgtcttt cctgttcttc tagggcgctt ccagataatt cttcctccgg
    21361 atcgctgcca ataatctgct gacgaagaaa gtcactcaca tcttctgaat caacagtaga
    21421 atcttctgat tgagaaattt cttcatccgg aagattttta ctgataaaca gttctaatcc
    21481 gtctcctttt ggcaaaactt ggaaagtgac agcttcgctt cctcggaact cctcttcgat
    21541 atcaacttct tccaaaatac tataaaagaa attttcgatt tctttgtgat tgccaagtaa
    21601 atccaaaaat gaaacgcccc gttcctctaa atcttcatga ccaattagta cacggatcgt
    21661 attttcatta atatgttcca tttccatttt gctacacctc actttgccac aatgtttaat
    21721 atagattcat tgtagcgaaa tcagcttaaa tgtaaagaaa aaaaatctcg ctgttaagcg
    21781 aatttaataa aaccagcgga tttttcaacc tttcaagcta tcttatttaa ctataacatt
    21841 tttggcagac gaatactata tagccgactt ttcagctaat tttccctctc tatttttcgt
    21901 gcaatcatca tcttctacta cctttttata catctaatca agaatacttt ttgtaaaaac
    21961 aaaaaaactt ggaaaaacta tctttgtaat agt
//
LOCUS       DADGKS010000047        21454 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.047, whole genome shotgun sequence.
ACCESSION   DADGKS010000047 DADGKS010000000
VERSION     DADGKS010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21454
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.047"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            2..400
                     /locus_tag="JXV47_001860"
     CDS             2..400
                     /locus_tag="JXV47_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAX1487899.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            384..1079
                     /locus_tag="JXV47_001861"
     CDS             384..1079
                     /locus_tag="JXV47_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HAX1487900.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1673..2560)
                     /locus_tag="JXV47_001862"
     CDS             complement(1673..2560)
                     /locus_tag="JXV47_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rotamase"
                     /protein_id="HAX1487901.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLIDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2745..3584
                     /locus_tag="JXV47_001863"
     CDS             2745..3584
                     /locus_tag="JXV47_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAX1487902.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3780..4754
                     /gene="sgrA"
                     /locus_tag="JXV47_001864"
     CDS             3780..4754
                     /gene="sgrA"
                     /locus_tag="JXV47_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HAX1487903.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5052..5408
                     /locus_tag="JXV47_001865"
     CDS             5052..5408
                     /locus_tag="JXV47_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487904.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5411..6568
                     /locus_tag="JXV47_001866"
     CDS             5411..6568
                     /locus_tag="JXV47_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487905.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6594..7034)
                     /locus_tag="JXV47_001867"
     CDS             complement(6594..7034)
                     /locus_tag="JXV47_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAX1487906.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7194..7700
                     /locus_tag="JXV47_001868"
     CDS             7194..7700
                     /locus_tag="JXV47_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAX1487907.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            7868..9781
                     /locus_tag="JXV47_001869"
     CDS             7868..9781
                     /locus_tag="JXV47_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAX1487908.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9786..10787
                     /locus_tag="JXV47_001870"
     CDS             9786..10787
                     /locus_tag="JXV47_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAX1487909.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(10989..11195)
                     /locus_tag="JXV47_001871"
     CDS             complement(10989..11195)
                     /locus_tag="JXV47_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HAX1487910.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11841..12689)
                     /locus_tag="JXV47_001872"
     CDS             complement(11841..12689)
                     /locus_tag="JXV47_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAX1487911.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12853..13755
                     /gene="gnd"
                     /locus_tag="JXV47_001873"
     CDS             12853..13755
                     /gene="gnd"
                     /locus_tag="JXV47_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HAX1487912.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            13757..14758
                     /locus_tag="JXV47_001874"
     CDS             13757..14758
                     /locus_tag="JXV47_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAX1487913.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFNVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMCEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14755..15039
                     /locus_tag="JXV47_001875"
     CDS             14755..15039
                     /locus_tag="JXV47_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAX1487914.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15072..15869
                     /locus_tag="JXV47_001876"
     CDS             15072..15869
                     /locus_tag="JXV47_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAX1487915.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLSSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            15883..16716
                     /locus_tag="JXV47_001877"
     CDS             15883..16716
                     /locus_tag="JXV47_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1487916.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16734..17591
                     /locus_tag="JXV47_001878"
     CDS             16734..17591
                     /locus_tag="JXV47_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAX1487917.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17613..18122
                     /locus_tag="JXV47_001879"
     CDS             17613..18122
                     /locus_tag="JXV47_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAX1487918.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18159..18560
                     /locus_tag="JXV47_001880"
     CDS             18159..18560
                     /locus_tag="JXV47_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487919.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18672..19025
                     /locus_tag="JXV47_001881"
     CDS             18672..19025
                     /locus_tag="JXV47_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487920.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19059..19502
                     /locus_tag="JXV47_001882"
     CDS             19059..19502
                     /locus_tag="JXV47_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAX1487921.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19519..20604
                     /gene="uxuA"
                     /locus_tag="JXV47_001883"
     CDS             19519..20604
                     /gene="uxuA"
                     /locus_tag="JXV47_001883"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAX1487922.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20597..21310
                     /locus_tag="JXV47_001884"
     CDS             20597..21310
                     /locus_tag="JXV47_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAX1487923.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
BASE COUNT         7385 a         3292 c         4473 g         6304 t
ORIGIN      
        1 gatgacgatc tttgaaacgg ttgtaacaga tgttggtata gaagcagaag tattcaggaa
       61 agaaaaaata atgattttat ttggagatga agcaccggaa acattaacag attattgtta
      121 taagattgaa ttgaatcagg taagaaaaga aataacttgt gatatgaagc tctgttttga
      181 taaacaaatg tatgtaatca cagcagtagg agatgttgtc caaactaatt tgaatgaatt
      241 aggacatatc acgataaaat ttgatggatc tcatgagccg gaacttccag gaacaatgta
      301 tgtagaagat aaggaaatgc cgcatttaag aaaggggaca atcattaaaa tcgatcaaga
      361 ggatcagaat gggggaaagc tatatggaaa tcatgcttga tacagcaaat acaaaaagta
      421 tttattcttg tcaacagttt ttgaatttaa caggcgtaac aacaaatcct acaattctga
      481 aaaaagaagg agcgtcaaac ttcttctcgc atatgaaaga aatcaaaaaa ataatcggac
      541 agattcctat ccatattcag acaataggaa gaacggaaga agaaatgata gaggatgctc
      601 gagttatcat agaagaactg ggaaaagata cgtttatcaa ggtgccggtg aatcaagcag
      661 gccttcaagc gatcaaaaag ttgaaaaaag aaggttattt gattaccggt acagctattt
      721 acacagaatt acaagggtat ttagctatta ataatggagc agattatatt gcaccttatt
      781 ataacaggat gcaaaatcaa ggcattgatg ctatgaaagt gattgattcg ttgcggactg
      841 agatcgaacg tacgcaaaga ccaacaaaaa tattagcagc tagtttcaaa aattgtgaac
      901 aagtcactac agccattcga tctggagctc atgcgataac gttaggtaaa gagctactag
      961 atcaagtatt agagatgccc tcgattgata aagcagtgag gggcttccaa gaagattggg
     1021 tgcaaacttt ccaagcagaa acgattggtg aactaaaaaa ggtcgctgat tacttctgaa
     1081 tcaatttctc cataaaataa acgatagcct tctcgaaaac tcgaggaggc tatctgacga
     1141 ttcaatattc attaatttaa agtttgggtg actattacta actattactt atttctcatt
     1201 taaacgatgt attccctaac ctctaataca tccttgtaac tctgaagtta cgccagtttt
     1261 gaataaattt cataaaaaca aatgaaaagt gtcgcataaa aatatctttc gtgtttctct
     1321 agtataacag aataagaaga acaagtccag aagggatatt tttagtcttt tttaaaataa
     1381 cttttcagtc gagtttgagt ttatgatagt tgtttttgaa gcgatacggc aagtgaaaaa
     1441 atagggaagc atgaaagaat ctacttaatg gcgcattgat tcatgtgata gaaataaaaa
     1501 acttttttaa attatatcct catgattgta acaaatccag tgatttgttt tggtacaaat
     1561 aaaaaaaggc cccgatgaag ttgtggcaaa agtggtttgc ctcaaaaata agaaggaatt
     1621 tccaaaaatc acttctcaaa ttttgccaca tccccaattg ggtcaaattt gtttatttga
     1681 atatattttt tacataagga tctttaatag ttacattgtc ttttttcatc actttacgga
     1741 ttgttttatc catgaattcc gtatcaagag tttttgcttc ggtagcaatt ttttctagct
     1801 cagatttgta tttgtcttta ttagaacctt tatcctgttt ttttaccatt tttactagat
     1861 aatagctttg ctgataagtc gttggatctg ttacaggaat gatatcagaa acttccccgt
     1921 tttttagttt aaatgctgct ttttttactt cagtaggaat ctctggattg gttgaatcaa
     1981 aattcatttt tccatcagtt tcctttaatg ttttattttt tccataagct tgaacaagct
     2041 tggagaaatt ttctccttca tttgcttctt tttttgcttt atctgcttct tctttagtcg
     2101 aaaatagaat gatctgtgta ctaacttctg gatagaattc tttccaagca gtgtctagat
     2161 ctttatctat taattttaca ttggctttca aaccgtattg gaaagccagc atctgtttaa
     2221 agagtttctt atatgtctct tctgtttggc caactgcttt taattgttcc ttgtagtttg
     2281 gaccgagttt tttgatttgt tcattatatt cttttgttac ttcctttgaa gaaatctctt
     2341 ttccgtatac atcatcaaat gctttgaaga caatcatttt ttttaatagt gtttgattat
     2401 ttgatttaac ttttgggtta tcataaaaat cctgaactgt aagtgttcca cctttaaacg
     2461 ttgcaatcgt ttcattggac ttgctacaac ctgagaatag taaaattgca catgctgaaa
     2521 ggcacataat tagtagttgt tttttcaaaa aatttcccat cctttcctta ttaaaaacag
     2581 tctaacagaa gaattaggga gacagtcttt cattttcgta aggttgctgt agatattctt
     2641 agttcgtaaa aatctattct ctctatgatg gagaacattt acatagtttt cacgagacaa
     2701 gaaagaaaag ggttgttaaa cttaatataa aggagggatg aaagatgatc aggattattc
     2761 ggttgattgg atctgtttta atagtcttag ttggttttgt tttaggaatt cttgtcaata
     2821 atgcacttgc ggatatgttt attggaaata gtgaatggat tggagcaatt gccggtacgg
     2881 tcggacattt agctgttttt ttactagctt tatttcttgc tagtaaggtc gaaggaaaaa
     2941 gaatagaaga ttatggtgtt tctgttcgag gaaaagactg ggggtattta gcgggaggtc
     3001 tcgttgttgg aattggagtg tttctgctta ttactagtcc attatatttg acgggggcgt
     3061 atcggttaga ttcaggaaac gcaaacattg tgccgctgat aacgagtttt attttattta
     3121 ttgcagtggg ggcatcagaa gagcttttat tccgtggctt ttttcagcat cagatgctta
     3181 gatttggtcc gttaatagca atgattggat ctgctgcatt atttgctctt ttgcacggat
     3241 tgaatcctaa catgacattt ctggcagttt tcaatatctt tttagcaggt tgctttttca
     3301 gcgcacttat ctacagtaca ggaagtttat ttacggctat tggtgctcat attacttgga
     3361 attggacaca aggagctatt ttgggtatac cagtcagcgg aacgcaagaa caaggttttt
     3421 tctccactct gatccaatcg caaaatacaa taattactgg gggaaacttt ggggctgaag
     3481 catctatatc aactacatta ttcttgttag tcttgattgt tggtttgtta ctctatgcat
     3541 ataaaacaaa gcggatgaag aaatacactg ctgtttatca ataaaagatg aagaaagcaa
     3601 ggctgatatc ggtcttgctt ttttaagtct gtcattgatt aaacgaaaaa gtaaacaaat
     3661 tcaagcgaat acacgacatc ttttgttaga ttttcacaac tgactgtcgt gttctcatca
     3721 ttttcatttt atataattcc tttatcaaat agaaggtaat tatatggaga gtgatagaaa
     3781 tgaagaaaac agcgaccgta ttatttgtta ttcttgggct gagtataatt gcagcaatga
     3841 ttggaatcag tacttctgca aatgaacggg caaatgagaa tctttcattt actgtgaaaa
     3901 ctgatcggat tgtttatgac atgacacaac aagtcattac tattccagtc aaaccaaaca
     3961 aaagcgtgaa tgctagtgat gtacatgctg ttctaacata tggttgggat ggtaatggaa
     4021 gttcagaaaa agttattggg gaagtttatt taaaagacgt acaatggacc gctggtattg
     4081 agtatacaat aatgatttct gcagaactat cgattgatga gatcaagagt aaagataaag
     4141 ttgatttgat tgttttttat gatggacaga tgacgatcac ggagaatttg aaaccaagca
     4201 gttggacagt tgttggaccg ccaagcagta cggatagcac aagtagtgaa agcagtacag
     4261 aaaacacgag cggtgaaagc agtacagaga gtacgagcag tgaaagtagc acagaaaaca
     4321 cgagcagcga aagcagtacg gagagtacga gtagtgaaag tagcacagga agcacgagca
     4381 gcgaaagcag tacggagagt acgagtagtg aaagtagcac aggaagcatg agtagtgaga
     4441 gtagcacagg aagcacgagc agcgaaagca gcacaggaaa agtaaataat gaacttgatt
     4501 tggtacctat cataccaact aaggaacaaa agagaaatgc agggagcaac ctaaaaagtg
     4561 tgctaaaaca gcctgatttt gtttctcgtg gaattgatca tcaagaaaaa gcgaaagaaa
     4621 cagataatag aaaaagcgat ttaccagaaa ctggtagtag aaccttgaac aagctaatta
     4681 catggatggg tgtgttactc attttgattg taggagcaag ctattttcgt tctctcttcc
     4741 atcgagtgaa ataaagaata aaagcaacag atctaaaatt gaataaaacg atagattttt
     4801 gagtgaatat ttcattcgag agtgctgtat tgcctggcga agttgtagct ttgccagatc
     4861 tatttttgtt tactaacata tttgagaaac aggaaataac aggaacacaa atggaaaata
     4921 agagcaagaa taattgacaa tgcacactgc gcatggtagt atctctgaaa aatcagtaac
     4981 gaatctattt gtacgttatt catgtagctg tcggaataag tctaaataat agataaaaag
     5041 gagtatgtac tttgtttgaa gaatttattg atatcaatga aaggcaagta tatcaatttt
     5101 tgaactattg ttatgaaaga gacgagaaat tatatgtggt gaaggatatc gctttagatc
     5161 taaactacac cctggctaag atgaattcgg tgattcaaca agcagaatcg ttttgcgaaa
     5221 ggtatccaga atataaatta tcttttcttt cagaaaacaa gatgataaaa gtcgagtttt
     5281 cttctcagtt tttactgagt aaagtttatt ctatactttt agagggaacg attggttata
     5341 ttttactgga ttcactttac aaaggtactt atcaatcctt agaaaatctt agtcaaaaaa
     5401 ttatataagt ttgcgtacga ttcaaagaaa attaagagaa cttaatacta ttttgaaaaa
     5461 ctatcattta tcttgcagct tgaaaaaagg taatccgata gaaggagaag aataccgtat
     5521 ccgatacttt tttcacttga tgtattggca gtcattcgac gaaaatcatt ctgatatatt
     5581 atcaagtata aaaaataaac gtcaactatt agaaaaattt gcgaaacatg cgccatatac
     5641 gcgtagtata gatagaaaga aatggatcag cctactaaga atttcgttgc aacgaatgaa
     5701 acaaggccac tcgattacgt atgtcccaga agagatgaac aaatttgtgc atccattgat
     5761 aacaaaagaa gagtttacgc attacatact agagcctttt tttgaagcaa acttctggtc
     5821 gatgaatcac atcactccaa cagagcaagc ttacctttat tttatgtttg gtgtaatgaa
     5881 cacctatttg gaagaagatt tgttggatac tccagataaa gtacaagaaa gttggggctg
     5941 gattgaatcg tctattgtag aaaattttga aaaaaacttc aagatttgtt ttacaacttc
     6001 agaaaaaaat tatctatatg tcaatttggc aatgatccat ttgtattcaa gggtttttgg
     6061 gacaaaaaag aaggtggatg cttttggaaa atcagcagaa gacagagatt ttcagcatat
     6121 atttccagtg atgtatccaa tcatgcaaca gttttttagt ggggtagctc gcagaattcc
     6181 agagcttaat acttattatg aaaagaacag acggttgatt tttcaatact gtatgttagt
     6241 cagggatatt tttataaaac acgaacaacc tgtcatattc tatattcaat caaagtatgg
     6301 taaaacacag gaattatggg caaagaaaag gatattatct atgactgaac gcccaataaa
     6361 atatagtgca tccgctgatc agttacctga tattgtcatt agcgattatc ctatcgacaa
     6421 aaaggcatat gatcaaacga atacacagat attttactgg aatggacaac ctacaaaaaa
     6481 tgattgggcg cgtctgaaag ctgaaatcat aaaaatcagg aatgagaaaa atagatccat
     6541 attggaaaaa ttggatttcg ttaattaaga aaagcagatt gtttatgcca aaattaagac
     6601 attgcaaaaa gattattttc tttaaaatcg acaagatgac cagaaagcaa gagttcgttg
     6661 agctcttgct ttcttttagt tttagaaagg aacatcctga ttttatcttc gctaaatcca
     6721 gtcaaaagtt ttgcagattg gtcgtagata atcggttttt tcaataaaga aggggatgta
     6781 cgaatctcaa tatatagttc actcaaactg agttcatcta ttctgtgaac aagattttta
     6841 taactaatag aatgagtaga gagcatttcg gtcacgccgt tgtttgtcaa ttttagtaag
     6901 tggataaatt catttttggt tagtggttga cgaattaagt tctgttcgat aaacggtata
     6961 tcatggacga taagccaacg ttttgcgcgt cttgaagacg agcagccaga acctgtatac
     7021 aatttaatca tcatacattc ctccaatagc taagtattta tgaaataata acatgaagaa
     7081 atagtcgaaa agtgccattt agaggtgtaa aataagaaaa tgttgtcacg tataatggaa
     7141 ctagctagat aagaaatact attaaatcaa gaaaaaagaa agaaggcaca agtatgtcaa
     7201 acacagccga cgcaatagta gtgatcgatt tacaaaaagg ggtatgtttt gattcttcgc
     7261 cgatacacga attagaaaca gtgacagcat tagtgaataa aagaatcaaa acatacgaaa
     7321 cgattgggaa accagttatt ttcgttcaac acgaagatgc tcaattagtg ccacaaacaa
     7381 aaccatggga gctattgtcg gaattatcta ttcctgagca cagttatttt gtgagaaaaa
     7441 cccatgcgaa ttcattttat aagactaatt tgagtgtttt attaactgaa ttggactgtc
     7501 attcgatcga attatgtggg gcacaagcag agtattgtat agatacgact gtgaagtttg
     7561 ctcatggatt aggataccag cttatgatgt gtagaggagc aacgacaact tatgataatc
     7621 cttttatgaa agcaaaggaa acaatcgctt tttacgagaa aatttgggat aaacgatttc
     7681 tgacattttt ggagcaataa gttgtttctt cgtttaaaaa aagcagaatg gatactggtt
     7741 tatccattct gctttattac gtaaaatgag aaaataatcc tgttctattt ttatgggata
     7801 aaccatttat tttttgtata aaaaatgttt gcgtttacat ataattctcc tagaaacata
     7861 aaaaggagtg aatagcttga gaacaaaaca agtattaaag ggagcgttgg tcatcttatt
     7921 tgctgtaagt acaagcgtcc cgcaatggac agtatatgga gagagcattt cttccgaatc
     7981 ggaatctcgg gaggtagaaa ccacagaaac tactgatgct ggaaatgaaa cgaaatcgag
     8041 tacttcacaa acagaaacaa atactgaaac aacggttgag acatctgtta ctagcacaga
     8101 tcaagaaacg accgctacca cagataacca acaaacagaa gaagcaacag ctacaaaaat
     8161 gtcaaacgac gaatcctctt ctgctaaagt aagtgacaaa gagaatggga cagaaaatga
     8221 tgatatcggt aaaggtgaaa atttcaatgg taaagaatat ttgaattact tcggtaaaca
     8281 gatgacagaa atacttaatg gaccaacaga agacatcaag tcaaaattaa tagagttatt
     8341 agtcactgag cttgctgtta atgattatgg tgtagataaa gagattatca aacatctgat
     8401 tgctacttat ctattgtacg atatcgcttt tgcaaaaaac agtgtgttga tgtcgatgct
     8461 tggaggtaca gatgatggga caacgcctac agaaaacaca ggcttctatc caaatacaaa
     8521 acaacttcat caaactgtac taaacaaaca agatggcaaa atgatggatg tatatgcata
     8581 ttatgtcgat caaggttcag ataaaacagt catgatccat ggcggatttc gagggaattg
     8641 gaataacggg atcgttacag aagaatacaa tgatttttat aaggccgggt ataatttatt
     8701 atttgttgat tccagagcga ctggtaatag cggaggcgat tatgtgacct atggacaata
     8761 tgagtcagat gacgtccttt actggataaa tcaagaagtt cgagagcggc catctcaaaa
     8821 gattttactt tatggtggtt cgatgggagc agctacgatg atgtctgtat tagcgaaaga
     8881 tattcctgtc aatgtcaaag gaattattga aaattgcgga tttgcatcaa ttgatgaaca
     8941 actacgtttt acgtacagcc agacagtagc ccccgcacta ccggatgcca taaaaaatca
     9001 gttagacatc attggggatc aagagcatga agatttattt atgggccttt tgaaacaata
     9061 ctattttgat caggagatgc atttggatac aaaagctgct ctacctacga ttggaatgtc
     9121 agattcattg cctaaattga ttatccatgg aacagcagat gatgtagtac ctgtgtctaa
     9181 cgcgcaaaaa ttatatgagt tatcaggagg gtataaagat cttttattag tagaaggagc
     9241 agggcatgga aaggcacagg aagttgacca tgctgcctac acgaaacatg taacggactt
     9301 tttgaaagta gtgttccatg atcagataaa cgtaaagtat gtggatgaaa acaataaaag
     9361 tctactcaaa gaccaggacg aaatccagct ttacggagct tatggagaaa attatatgac
     9421 agagcaaaag acattcgaag gatacgaatt agcaaatgtt gaaggaccga ctgaagggat
     9481 ttttaatgag acgataccaa ctattatttt ctattacaaa aaaatcccag tagctccacc
     9541 aaaaaagcaa gatccgacag agaatgcaga caataaggga aagaatgaac ctcgagagga
     9601 tcaatcaagt gatgatacgc aaccgattca gatgacagtg aaagtacaaa aaaagacaga
     9661 tgcaaaaaaa agaatgttgc cgaaaactgg agaaaagaaa cattcgcttc tcatttattc
     9721 aggtggattt ttatctgtta gcacgattat cacatggatt tggcgaagaa agagagggta
     9781 aatgaatgaa atggttcaag cgaatagtga ttgcagtacc agttatcatc gtagttattt
     9841 tagtcactgt atttttgatt aatcaaatca caccaaagcc gattagcttg cttgttagaa
     9901 aacaatttga cacaagtgaa aaagaacaag tatatgcccg accagatgat ttccagcaaa
     9961 aaatcgaaca aatcgatata aaaaaagaaa tatcctatcc ttcaaagtac aaaaataata
    10021 atatggatat ctacacaccg aaagtggaaa agaaaaaatt accgattctt ttctggatgc
    10081 atggaggcgc atatgtagga ggggataaaa atgattgtcg tgattatttg gaatatctat
    10141 gttcagacac gcagcaaatc atcgtaaata tagattatga acgatcaccg gaagcaaaac
    10201 atcctacacc agttatccaa ttgaacgaag ccattcaagc agctaaaaaa gagataaaag
    10261 atcaagcaga ttggtcgaat atttcgattg gtggaaattc ggcaggtgca caaattagtg
    10321 gagaatattt gttagcactt caaaatgaag aaattaaaaa agctgatcat cttgatccga
    10381 ctttggagaa caagcagatt acgaagttta tttctttgtc tggtctgttg gatccttctg
    10441 cacttactca agtaagtgat aaaatctcta gctttcttta tgaaaaatgt ggatgggctt
    10501 actttgataa taaggacttt gaacaatcag agaaggtcaa aagtttagcc ttggtcagac
    10561 atgcggatcg ttggacgcaa aacacattct taacggatgg aaatacaaat acgtttacga
    10621 aacaaatgga agaagtaact tctgtatttg agaaagcggg ggtgaaagtc acaaaagtag
    10681 attatgcgga gaaaaatgct gttttgaacc atgaatatca gtttgatttc agcaataaac
    10741 aagcgcaaga aacatatcaa aagttagtaa tgtttttcaa ggagtaaagt cttatgatgc
    10801 aaaagaggtt gtaatctgtc acttagctcc aagtcacaag gagcaatttc aataaacaag
    10861 cttttcatgg tttatgaata ttgtaacttg tgactgagga gttagagatg gcaaggggca
    10921 ccttttattc gaaatttggg aatatcacac gattattgtc acgatctctt ttacgtaaat
    10981 tttataagtc agatttgttg ttttgatcgt ttaaaaaaag caacaaatcc gaagcctgcg
    11041 gaggcaagaa gggacaaaaa gccgagtggt aagcaaaaga atgctggttc cactaatatt
    11101 ccgttgttat tgatataagg ctgggaacaa agatgaatag caaataaaat caatgcacta
    11161 gcgaaaaaaa gcaaagaaat atggatagct ttcataagca gcacctcctt ttttataatt
    11221 gtatgataaa tagattaaga atctataaat gtgacaagtt tgttaggatg tgaataaaat
    11281 gatcatctag cgaacttgaa acaaagatgg ctaatgataa gcaattaatg attcagcaat
    11341 cagataggta caaagtttac catcatacgt ctagaccaat aatagaaaat atgggaatat
    11401 aatagaaaag atttaggata cccccaaaag aatttcccca aaaattcgat gtatcctaaa
    11461 cttttttatt ttacataaca atcatatcaa ctgtgaaata aaattacaaa tgataaccta
    11521 aaatgaggcc aaaagccagt gttatcaagg aaatacttaa ttcaccaaaa ttttttttaa
    11581 ttttttagaa aataagaaac aaaaataata aaaaaaagaa aagataaatt ttttactact
    11641 gtatactaac tttgttatcg catctaacaa gtaactcgaa taataccaat acaaccttct
    11701 ccaaagatgc gatgacatac gttctaaccc accgactatt gatgttctgt accacccttg
    11761 cagaaccaaa aaagccacta ccaaatattt ggtagtggct ttttttgttt tatggatttt
    11821 tcgctttttc tgttatggtg ctattctttg atttcagaaa tagtatgtcg aactttagcg
    11881 atagaacgac gtgattcttt ttcgttgtaa aacatcaaaa tcacatatag agagtccaaa
    11941 atgcttagtt gagaaatacg ggaagctaaa gcttcagatc ggaattctgt ttcttcagaa
    12001 atagaaataa aaacgacatc gccaagttta gcaagggaag aattagcttg gctagtaata
    12061 acgattgttt ttgctccagt ttttcttacg gtttcagcaa tatggattgt ttcttttgat
    12121 tgccctgtgt gagaaatcaa aacagcacag tctttttccg tcaataaaga agcttccatc
    12181 aattgaatat ggtaatccgt gctgtgagaa gttgcgatag gggaacgcaa aaatttatga
    12241 taagcgtcag ttgctacaat ctctgaaccg ccaacaccga aaaaatagac acgtttagat
    12301 tcattgataa tagtagccgc tttttttaga tccttttgtt gtaacaactt ttttgtgtca
    12361 tttaaagttg aaatactaga ctcgaacacc ttttgcgcca tagtgagctc agtatctgtt
    12421 ttctgaatat tttcgtggat agaaatagca gatagatcat tttcttggat caacatggcc
    12481 attttaaaat ctttaaatcc attataacca agtttttttg taaattgaaa aaaagtagag
    12541 tcagcaatgc ccagttcact tgctaaattg ctaataggac tatgacttac tttgcttgga
    12601 ttttctaaaa tataatcggc gatagcctgt tcttttgggc tgaagtcgtt gtacattgtt
    12661 ttgatttgta gtcttatgga gacgctcatg agaattcctc attttcataa taagattatc
    12721 attttttccg ttctcattaa tgttaaagat acaaggagag taggaaaaaa tcaaacaaaa
    12781 aatatttttg taaaatctat ttacaaaaaa atttttttgt ataatgaggg tataagaaat
    12841 ggaggcgcta tcatggaaat tggtgtaatt ggtttgggaa aaatgggatt gaatttagct
    12901 ttaaacttaa aagagcacca tcacaaagta caaggactcg acatttcaag tacagctgtt
    12961 agtcaggcaa gagaaaatga cattcctgct tatcaagaga tctctgaatt tctagctact
    13021 tttgagcaga aaaaaatcat ctggttaatg cttcctgctg gagagataac cgaaaacatg
    13081 ttaagaaaac tttttccaaa actcggacca ggagacatta ttattgaagg cggaaactct
    13141 tattataaag attcaatccg tcgagcagaa gagtttcaga aaaatgaaat cggttacttg
    13201 gattgtggga cttctggagg aatcgaagga gcacgacatc aagcctgctt aatgattgga
    13261 ggagataaag aaacttttct atccgtggaa caattattca aagatgtagc aattgaaaga
    13321 ggatatctgt atgctggtgc atccggaagc ggacacttct tgaaaatgat ccataatgga
    13381 atcgaatatg gaatgatgca agcaatcggt gaaggattcc aacttgtaca aaaaagtgag
    13441 tatgcttttg acttggaaca agtcgcacgt gtttggaatc atggttcggt gattcgcggc
    13501 tggctgatgg aaatcatgga agatcagtta aacgaacatc ccaatttaag taattatcgg
    13561 ggaatcgttt ctgcatcagg tgaagcaaaa tggacggttg aaacagcgct agaaatggct
    13621 gttccagttc cagtaattgc aactagtttg ttcatgagga atctttcaca ggaagaagat
    13681 agtttttcag caaaagtagt ttcagcacta agaaatgggt ttggcggaca tgaaatagtt
    13741 gaaaagggtg agtaaaatgc cagattatca tatagcaatc gttaattcca gcagtttcgg
    13801 aagagtcttt ccacaccact tggaaagatt aaagtcagtt ggagacgttc atttctttaa
    13861 tgttgatcaa gagattccag gaaaagaact agcggagtta cttaaaggat tcaatatcat
    13921 tattgcaagt gttacgccat tttttcgacg agattttttt gaaaacaaag atgaactgct
    13981 attgatttcc cgacatggta ttggttacaa caatattgat ttaaaagcag caaaagaaca
    14041 ccagacaatc gtatctatca tacctgcttt agttgaacga aatgctgtag cagaaaataa
    14101 tataactaat ttgttgtcca tgcttcgacg cacgacacaa gcacaagcaa gagtcaagga
    14161 cgatcgatgg gaagatcggg cggagttcgt cggtaggacg ctgtttaaca aaacagttgg
    14221 tgtgattggt gcaggaaata ccggaagcgg agtaatcgaa attttgcgta acggttttcg
    14281 ctgtgatgtt ctagcttatg atccttacaa atcagattta tacatcgaaa gctttggtgc
    14341 aaaaaaagta gaacttcaag aattactgga acaatcagat atcatttgtt tatgtgcgaa
    14401 tttgacagaa gagaactatc acatgatttc tgataaagaa gtcgatcaga tgaaagaaaa
    14461 tgtttatcta tctaatagtg caagaggcgc tctagttgat gaagaagcga tgattaatgg
    14521 tctgaaaagc ggaaagatcg caggatatgc cacagatgtt ttagaagaag aaccgggacg
    14581 tcaagatcat ccgtatttag cgtttgaaca agtagtgatt acgccacata tatcggccta
    14641 cacaagggaa tgtttagaag caatgtgtga aaaatgtgtc agagatgtcg aacagatcag
    14701 tcagcacctt cttcctgaac gttctgtcca gacaaagagc aactatataa aaggatgatg
    14761 aagaaaatgg tgaacggttt aaaagtgaaa acaggccctc aattttattt atatgaagaa
    14821 ggtggtattt caaaagtttc tgatctcttg aaatcatacg gcgcgaaaag agtactggtc
    14881 acccacggaa cggtatcatg ggaaaaggcg ctacctaaat tagtattttt gaatgacgaa
    14941 acgattcaat ttttttatca tcgttattct ggagaatgta gttatgctga agccagacga
    15001 atagctacaa tcatcaaaaa aatgaaatcg atttcgtagt tggcgttggc ggaggaaaac
    15061 tgaccgatct agtgggttat agtgccaatc ttgcaagaat cgatttcgga gtcatcccta
    15121 ctttagctag taattgtgct ccatggacac ctcttgctgt catgtataag gagaatggac
    15181 aagcagaagg gaaaacagaa cacttttaca gacaagctgc tttttttata acagatcccc
    15241 aattagtgat tgattcccct gttccatatt tcattgccgg gttagcagat acactagcaa
    15301 aatggtatga atctgagctc atcttagaac aagatttttt gcaagatgaa tcatttttga
    15361 agctagcaca agatactgcg aagatctgca aagaagagat tttgaatcat tctgctaaag
    15421 caatccaaga tatggcacaa agaaaactgt catcggagtt caaacagctt tcagagatta
    15481 tctttgctgt tgctggttta gttggaggat taggagataa atacgcaaga aatgtggcag
    15541 cacatgctat gcatgacgct atcagtaaat atattccgga aagccatcgt tttctacatg
    15601 gagaaaaagt agcgtatggg attttctatc aactggcact agaaggtcgc tgggaaaaaa
    15661 tagacgagtt atatcctttg tatcgggaat tagaactgcc ggtttctcta gaacaaatgg
    15721 gattatttcc gaaagataaa cagataatag ataaaatggc tgaatttatt gattcgaaag
    15781 agaaagtgca tttgattcct atagaggtaa cacagaaatc actgatacag tcaatgatgg
    15841 aactggaagg ttatatcaga aagatctgaa ggaggaggac acatggaaac attaagtgta
    15901 gtacaaagtt tgttgattgc tttatgggta gccgcggtta tgtcccgctg gttaggtgga
    15961 ggagccacgt tgaccttacg tttttctcct ttgatgactg gattagtcgt cgggttgatc
    16021 atgggggaag ttgcacaagc gatgattgtt acagccgctt tgcaaatgat ttatatgggg
    16081 gttttttctc caggaggatc aatgccagct gaaccatcta ttgcagcagc tatcgcagta
    16141 ccagtcgcat tattagggga tctgtcgcca gaagcagcga ttgccgttgc ggtgccagtc
    16201 ggattgctcg gaagttactt gtatcagttt cgttttttca tcaatacttt tttaggtaaa
    16261 tatacagaca aagctgtaga agatttgaat acaaaagcta tggcccgatc aattattctt
    16321 tatccaacgg ttgcctcatt tttattattc gttccgcttg ttttcattgc tttatattta
    16381 ggggcgccat tgatcgctga tgtaatcaaa gctttagagg gaacagtcgt tatccacatt
    16441 cttgaagtag taggtggagg gttagcggca atcggtatcg cgacaactgt atacgttatc
    16501 ggtcgaaaag attatctggt ctttttcttc cttgcttatt ttatgagtgt tgttttgaaa
    16561 tctttagata ttacgatggt tacttatgcc atttttggga ttattatcgc tttgatcttt
    16621 gtccagtcgc aaaaagggaa acaagtacag cctgccacaa gcaataacaa ttcagcatct
    16681 tttgatgacg aagatgacta tgatgacgga ttttaattta ggaggaatgg gaaatggctg
    16741 aaataatgga taatcaaaca ggtgctcctg aagaaatcac gaaaaaagat gtaacaaaag
    16801 cctatctgag atggcatttt gcaaacgaaa ttcctcactc ttttgaacgt tacttggcgc
    16861 catcactact atacggaatg atgccaatct tgaaaaaact ttataaagat gaagactctt
    16921 taaaagcagc atataaacgg cagttactgt tcttcaacac tcaattaagc tggggtggcg
    16981 gtgtgattac tggcctaatg tcttctatgg aacagcaaag agcagaagaa gagtatgaag
    17041 aaaaagagat cttgatgcag gatgacttga tgtataacac gaaagcggga ttgatggggg
    17101 cactagcagg aatcggagat gcaatcgatt caggaaccgt ccaatatatt tttatcgcaa
    17161 tcgcggtacc ttgggcacaa cagggaagtc ctttaggcgc actttttcct tttatctgct
    17221 ttgggttgta tcaggtttta ctaggggtat ttttcgcaag acaagctttc actatgggcc
    17281 gtaatgctac aggcctaaag caaaacactg gtgttcagac agcgattgaa atgctatcag
    17341 ttttagggtt gtttatgatg ggggtgcttg cgggaaacta tgtaaaagta gaatcttcat
    17401 tgaaatttgc gatatccgga cgtgagtttg ttatccagga aattcttgat caaatcgtgc
    17461 cagggatatt acctttagct gtcgtaatgg gtgtgtactt gttctatacg aaaaaaggat
    17521 tgaaagtcac acaagcatta ttatggctga ctggaatatt aattgtgcta gcaggaatcg
    17581 gtattttata aaaagaaggg aacgtgaata agatgggtgt agtcaattta gcgcgtgtgg
    17641 atgagcgttt gatccatggg caagtaatgg taacgttatc tcaaaaaagt ggagtgaatt
    17701 ccatttttgt tgtagacgaa gttgtagcaa aagataaatt tatgagagat ctttacaaaa
    17761 atgcaggaag ccgtacagga caaaaaacaa ttgtcattac accagagaaa gctaaattct
    17821 attgggatga atatcaattt aaagaataca attgtatttt gatcgcaaaa acagtccaaa
    17881 cgatttacga cttagtaaaa cacggaatcc ccatggaaga attgaatatt ggagggattg
    17941 ctcaaaaaaa tcctgataca gatcttttag tgacgaaatc tgtttattta aataaatcag
    18001 atgctgaaaa attgaaagaa atgaatgaac aatatggcgt aaagaatatt tattttcaag
    18061 ccactccatc tgcacctaaa acaggattaa aagatgtatt gaacaagttt gatttgtcat
    18121 aaacaaatgc ttagaaaaaa gataaagagg gcgaaaaaat gaagaagaac gagctgtttc
    18181 gtgattggga atttcgttat cgctatattt accgtaagcg ccgtacaaaa aagagtaaac
    18241 agcgttttct ttcagcatta gtatcagata tttacagtat gagaacagat gtgacagtca
    18301 ttgcttacga tacgctagcc taccgatcaa aaaatattta tgttggagat atcgaaaaag
    18361 cagagaaagt tatctgtact tattacgata cacccgttca tgcattagga agttatttca
    18421 tgtttgattg gaaagaccaa aggaaaaaaa caatctactc tatattattg tccttcattt
    18481 tgttgttcag tttaggttgg tggggaatga tgatatataa caaaaatcct catcacgtat
    18541 tcgatctgct atccgtataa acaggtatca ctgtactagc atttgggagc tactttttct
    18601 tattgggaaa agcagctcgc ggatggccta gcagacaaac ttttattcga aatacttcat
    18661 ccatattaac gatgctagaa atgatccgta cgattgatga tccgagtgta gcgtatgcgt
    18721 ttgttgatga aggctgttat ggagaaaagg gcttagacag cgtgagatcg ggtatgaaaa
    18781 aagaggctat tcttttttat ctagactctg ttggggcaga tacaccgcta cagttttcgg
    18841 gaaattattt ttcaaataaa gaacagtggc tgaaacaagt tgataagttg aaagaaaaaa
    18901 acgtcaatta tatttttagt gcaagaaaaa agcaagcgca gttcttctat ttgaccaaaa
    18961 cagatttacg agggaaaaca tttaattggc aaaatgccaa tcagattatt gctctttttc
    19021 gataagtaaa aagtgcaaaa caaggagtga gaagactaat gttggaaatc atgatcgtta
    19081 cacatggtaa gttgagcgaa ggactgaaag atgcggcgga agtaattgtc gggacatcga
    19141 gccatattga aacaatgtgc ttagagtctg gggaggacat ccaaacattc ggagagaagg
    19201 tcaaagaaaa attaactatg atcaacacag cagaacccat gctagtattt gttgatctaa
    19261 ttagcgcaag tccgtacaat caagcgctct tggcagtcaa tgaactgact gaagaaaaga
    19321 aagcagccac ttatgtcata gggggcgtga atctgccaat gttgttagaa gcaatcaatc
    19381 atcagatgct tcacacaccg atagaagaag cggtggaaca aattgtcaaa caaggaaaag
    19441 ataatttaac tgtttggcat gcttcagcgg aagaaaaaaa attagatgag gacgattttt
    19501 agaaggaagg ctgaaaagat gaagtgggga tttagatggt atggtgaaaa aggggattcg
    19561 atcccattaa aatatgttcg ccaaataccg ggaataaatg ggataattgg aactttgctg
    19621 actaaaatgc ctggagatgt ttgggagatt tcagaaattg aggagttgaa agcatctgtt
    19681 gagagccaag gactggaact gcttggaatt gaaagtgtag cgatccacga tgcaatcaag
    19741 gcagggacag atgaacgaga ttactatatt gataactata tacgaacaat caaaaacttg
    19801 tctcgatgtg gggttcgatt gatttgttat agcttcaaac caatttttgg atgggcgaaa
    19861 actgatttgt ttaatgaaaa caacgatgga agctattctc ttttatacga tcagaaaatc
    19921 gtcgatcaga tggagccagg agaaatgtat caattgatac acagccagtc aaagggattc
    19981 aaattgccgg gttgggaaga agaacggttg aaaaaattcg ctcagctgga aaaactgtat
    20041 gaaggaatga ccgaagaaga attatttgaa aatctgactt attttttaga aaaagtgatt
    20101 ccagtgtgcg aaaaagcaga tgtaaaaatg gctatccatc cagatgatcc gccatgggaa
    20161 ctttttggtt ttcctagagt gacgaaaaat cttggcgact tgaagaaaat tctaaatgca
    20221 gtagattctc catataatgg actaacgctg tgcacaggat ctttaggggc aaatccggaa
    20281 aacgatttag ttgaaatcat ccatgaggta ggttcgcgca tccattttgt ccacttcaga
    20341 aacgtggagt ttttaggaga aagaaagttc aaagaaacgg cacatccctc tacagaaggc
    20401 tcccttgata tgtatcatat tatgaaagcg ttggtgcaag aagggttcga cggtcctata
    20461 cgccctgatc atggtagaac cgtgtggggt gaagtggcta tgcctggata tggcctgtat
    20521 gatcgtgcaa tgggactcac ttacatgcaa ggtctatatg aggcgataag taaggaaaaa
    20581 ccactgggag agcattatga ataaaatcaa gctcttcatc tttgatatgg atggcctttt
    20641 attagaaact ggacgtttag cttatcgtgc ttatgtaaaa tcagcacaaa agtatgatta
    20701 tgaaatgcgt aaggaagtct attatttact aactggccaa acagaaatgg cgataagaga
    20761 acaaatgggc attttgtacg gagaagatgt tccatatatc aaatggcgag aagcaatcaa
    20821 tcaatataaa gaaaaaatcg tgaaagaaga taagagagta tatacgaaaa aaggagcaga
    20881 agaaatttta tcttttgcaa aagaaagagg aatccataca atcgtggctt cgtctaatac
    20941 acgggtaaaa gtagaaatgt atttaaaaat ggaaaatcta tatgccttgt ttgatcaaat
    21001 catttcaggg gatgatgtaa aaaaaggaaa gccggaacca gagatctttt tgaaagcttg
    21061 ttcaaaaatg aatattcctc caagtgaagc acttgtattt gaagactcga ttgcagggat
    21121 cgaagcagca aggcgagcgg gcattttgtc ttttctcatc aaagatcatt tgatagggtt
    21181 gcccgatcat aatgggaagc ataagttgaa agtagatgta agtttatatg aatccaataa
    21241 agcagactat gaattttatg acctgcatca agcaaaacga tttttagaaa gtaaagggtt
    21301 gtatctctaa taaagaggac tattttctag tcctctttat ttattgtcct gcacgactga
    21361 gggaacagat gaaaaagaag taatttttta ttttgaagta tctaccttat ttgtagtgaa
    21421 caatttagaa caaacacaaa acgcatctac tgtt
//
LOCUS       DADGKS010000048        21342 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.048, whole genome shotgun sequence.
ACCESSION   DADGKS010000048 DADGKS010000000
VERSION     DADGKS010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21342
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.048"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            205..2676
                     /locus_tag="JXV47_001885"
     CDS             205..2676
                     /locus_tag="JXV47_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAX1487924.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(2779..4515)
                     /locus_tag="JXV47_001886"
     CDS             complement(2779..4515)
                     /locus_tag="JXV47_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HAX1487925.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(4512..5216)
                     /locus_tag="JXV47_001887"
     CDS             complement(4512..5216)
                     /locus_tag="JXV47_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1487926.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5347..5850
                     /locus_tag="JXV47_001888"
     CDS             5347..5850
                     /locus_tag="JXV47_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HAX1487927.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            5810..6148
                     /locus_tag="JXV47_001889"
     CDS             5810..6148
                     /locus_tag="JXV47_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HAX1487928.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6169..7587
                     /gene="ffh"
                     /locus_tag="JXV47_001890"
     CDS             6169..7587
                     /gene="ffh"
                     /locus_tag="JXV47_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HAX1487929.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            7699..8277
                     /locus_tag="JXV47_001891"
     CDS             7699..8277
                     /locus_tag="JXV47_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HAX1487930.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8281..8802
                     /locus_tag="JXV47_001892"
     CDS             8281..8802
                     /locus_tag="JXV47_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAX1487931.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(8881..9435)
                     /locus_tag="JXV47_001893"
     CDS             complement(8881..9435)
                     /locus_tag="JXV47_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAX1487932.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            9688..9963
                     /gene="rpsP"
                     /locus_tag="JXV47_001894"
     CDS             9688..9963
                     /gene="rpsP"
                     /locus_tag="JXV47_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HAX1487933.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            9975..10226
                     /locus_tag="JXV47_001895"
     CDS             9975..10226
                     /locus_tag="JXV47_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAX1487934.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            10351..11142
                     /locus_tag="JXV47_001896"
     CDS             10351..11142
                     /locus_tag="JXV47_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487935.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            11312..11833
                     /gene="rimM"
                     /locus_tag="JXV47_001897"
     CDS             11312..11833
                     /gene="rimM"
                     /locus_tag="JXV47_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HAX1487936.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            11823..12584
                     /gene="trmD"
                     /locus_tag="JXV47_001898"
     CDS             11823..12584
                     /gene="trmD"
                     /locus_tag="JXV47_001898"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HAX1487937.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            12720..13067
                     /gene="rplS"
                     /locus_tag="JXV47_001899"
     CDS             12720..13067
                     /gene="rplS"
                     /locus_tag="JXV47_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HAX1487938.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            13440..14102
                     /locus_tag="JXV47_001900"
     CDS             13440..14102
                     /locus_tag="JXV47_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487939.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            14181..17408
                     /gene="fss3"
                     /locus_tag="JXV47_001901"
     CDS             14181..17408
                     /gene="fss3"
                     /locus_tag="JXV47_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HAX1487940.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITGAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            17522..17836
                     /locus_tag="JXV47_001902"
     CDS             17522..17836
                     /locus_tag="JXV47_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAX1487941.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            17849..18223
                     /locus_tag="JXV47_001903"
     CDS             17849..18223
                     /locus_tag="JXV47_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAX1487942.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            18233..18577
                     /locus_tag="JXV47_001904"
     CDS             18233..18577
                     /locus_tag="JXV47_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HAX1487943.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDVEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            18648..20000
                     /locus_tag="JXV47_001905"
     CDS             18648..20000
                     /locus_tag="JXV47_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAX1487944.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVDKKFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG
                     "
     gene            20060..21202
                     /locus_tag="JXV47_001906"
     CDS             20060..21202
                     /locus_tag="JXV47_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HAX1487945.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGMLLGNFEQGNRVYEITGTAPTLSTKQGGTKIMLRKNETEYQ
                     EVKPGNSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVKTDDL"
BASE COUNT         7116 a         3809 c         4549 g         5868 t
ORIGIN      
        1 gttgaaacga agaaaaagtg ttagtagaaa atcgccttcg attttccacc aacacaaaat
       61 attatagaac cctttttttt tgctatatga caggaatgaa aggtgtttgc aagcttaatg
      121 tgaggaacac tttccatatc tgttctatac tggataggag aagtttggaa atatccagaa
      181 aacgaaatca atcgaggtag ccacatgaag aataaatgga taaatcgaag taaaaaaaag
      241 aaagtaacac aaagatcatc agataaagtc atccgtcttt ttccatcgta taaagaagga
      301 ttaacggcag atcaagtcaa ggaacgaata gaaaaaggtg cagcaaataa ttcagtcgat
      361 cccacattca aaacaaatca gcaaatcgta ttggaaaaca tatttacgta tttcaatttg
      421 atctttctta tcttagccat tttgctttgt ttagtagaat cctataagaa cttgactttt
      481 ttaccagtta tcatagccaa tacaggaatc gccatttttc aggaaattcg atccaaaaag
      541 atcttggacg aactaaatgt tttaaataca gcaaaagtca atgtcatacg agacgggata
      601 gaacaaacaa tagatataga agaccttgta atagatgaca ttgttatttt agagactgga
      661 tatcaaattc cagcagatgc agaggtcgtg gaagggaaac tgcaagttaa tgaggcttta
      721 ttgacaggcg aagcagatga aataaccaaa gaaataggtg atccattaat gtccggcagt
      781 ttcattgttt ccggaaaagc ttacgcccga ttagacaaag ttggagcaga ttcgtatatt
      841 tcccagctga cagtcaaagc caagacaatg ggagaaggag aacagtcgga gatgattgct
      901 tctcttaatc aattgatcaa atggattggg atcatcatta ttcctatcgg tatcctgctt
      961 ttttctcaaa gttacttttt taatggaaac acgatcaaag aaagtgtcgt tgcaatggaa
     1021 gcagcattga tcggtatgat acctgaagga ctgtacttgc tgacgacgat tgcattagca
     1081 ttaagtgcga ctaaactagc aaagcaaaga gttcttttac acaatatgaa aagcattgag
     1141 acattggcaa gggtaaatgt cctttgtgta gataaaacag gaacgatcac agaaaataaa
     1201 atgtctgttc aaaaaatgat cgtctctaaa aaacaagaaa taatcagtca gtcagatcaa
     1261 ttggaagcat gcattgctga ctatgcaaaa gcgatggcag gagacaatgc aacaatggaa
     1321 gctgttaaag catattttac aaaaaccact gatcaatcct atcaccatgt tattcctttt
     1381 tcttctgtcc aaaaattcag cagtgtagcg ttggcagaca aggtgtatgt tttaggagcg
     1441 cccgaaatgg ttttgcgcga tcaattgccg gaatatgcgg aagagtttgt ttctttcgct
     1501 gaaaaaggct atcgcgtgtt ggtctttggt gtgtacgatg ggattcttga agaaccagta
     1561 ttgacagaag cagtcacacc attaggctat attctgattg ctaatcctat cagaaaagaa
     1621 gcaagagcca catttgatta cttcaaaaaa cagcaagtag ccatcaaagt gatttctgga
     1681 gataatccgc tcaccgtatc caatgtagct gtccaagcag ggatttcaca tgctgatcag
     1741 tacgttgatg catctaaatt atcagaagaa gaatatgaag cagctgtcga aaaatataca
     1801 gtttttggac gcgtcaagcc agaacaaaag aaaatcttcg ttcaattgat aaagcgtaac
     1861 aatacagtag ctatgacagg tgatggcgtg aatgatattc tagccatgaa agaagcagac
     1921 tgcagtatag cgatggcttc cggaaatgaa gccgccatgc aggcctcaca agtggtctta
     1981 cttgattctg acttttcacg catgccagaa gttgttgcag aaggacggcg cgttgtgaac
     2041 aatattgagc gatcagccag cttgttttta gtgaagaata ttttctcctt tttgctctca
     2101 ctgttttcag tgatctttgc tctgacctat cctttagaac catcacaaat cacattgatt
     2161 agtttgttta ctatcggact tccatctttc ttgcttgctc tagaagaaaa caaaaagcga
     2221 atcagaggga aattcatcat gaatgtgatg gaaaaagctg tgccaggtgg actaacagat
     2281 atgatcgtag tcggtgcgtt ggtgatctgc ggggtgactt tgaatctaaa taaaacagat
     2341 gtttctacag catctaccat gcttttgatt gcagtagggt tcctcgttct ctataaaatc
     2401 tgttcaccgc tgaataaatt cagaagtcag atcattcttt tctgtgctag cggtaacttt
     2461 ttttcggtca tctttttgca taagctgttt tcaatcaccg gtatctcagc tgtatcactt
     2521 ttgctgttga gcattctatt tttctcggca gattcgattt ttaggcattt gaccacattg
     2581 gtagaatatt tgtttgaacg taaaaatgaa aaagagcaaa agccgtttag tcgcgtagct
     2641 aaaaaatttc tatcgatatt taaacgagaa aattgacgaa aagtatctca aaaaagagta
     2701 aaaaagaaca accactcgtg tatctttcga agcaggatga gtcatccaac tttaaaacgc
     2761 acgagcagtt gctctttttt acattttcgg aatggtaacg gtgaaagtcg aacctgttcc
     2821 aagatgactg tctacagtaa tcgtaccatt aaggagttgc acgtagtctt ttacaatcgc
     2881 taaccctaat ccggtcccgc ctgaatgtcg gcttcgcgcc ttgtctacgc ggtaaaaacg
     2941 ctcaaagatc cgttcctgat cctcaatgtc gatacctata ccaaagtctt ggacagaaaa
     3001 cgatagatca tctgttgcct gatagcggat aataatctcg ctgtcgcttt ttgaatattg
     3061 gacagcattt tcaattagat ttttgataat tggataaagg atatctgttt tagtagtaaa
     3121 tggttcgttc tttccaatca atcgaatcgt caaccgtttc ttttcgatga ttggctgata
     3181 attttgaacg atttgctgga aataaggttc tgtataaatt gtctggatct cgtaagaatt
     3241 ctcgccatct tttgacagct ggatgatttc ccgaatcagt ttatctaacc ggatcgcatc
     3301 tttttgcatg atctcaagaa aagaagtcag agtttgcggg tcatcttttg caccatccag
     3361 taaagtctcg gtaaaaccaa tcagtgaagt cacaggagtt tttaattcgt gagagacgtt
     3421 gccaacgaaa tccttttgta gcttttctaa acgtcgcact ttcgttaagt catacgccac
     3481 ccctagaatc tgtccggtac cttctgaatt agtaaagtag cgcaaactca agtctaatgt
     3541 ctgccgacct tctgtaaggg tgatctcctg atggatcagc ggatgctcag gagtcacttg
     3601 atgaatcagc tgaatgagtt ttggctcttg aatgacttct gtgtaccgct gttcaggttg
     3661 atagcttacc acgtttaaat gtagctgcat ctttggatta agcagtagta aacgagaatc
     3721 agcatcatca atcaggaata cgccaatcat cagttcgttc agtaacgtat ataattgctc
     3781 ttctgtggta gtacacgccc gatacatctt actcatttgt tcgctcaacg cattaatcgt
     3841 ctgatacaat tcttcccatt gatcgggtgt ttgcatgatt acttccgcct gattaggatt
     3901 ttgcaccatt ttttttagta cgggcagcac ggttttcaat ggctggtttt tttgatagat
     3961 cagataatag atcattcctg caagaacaag gaagaaagac agaaagaaga aaaagaccca
     4021 acggcgaaaa ctctcagttc tcggtaaaaa accgcttgtc ggttctgcga tacgtaaaat
     4081 ggcttctaac tggccacttt ttttgactgg taatgcgaca tataaaagat cctcattcaa
     4141 agtagtactt ttgcgcaaag cgctacctag gttcccacca ttcaatacgg ctttgatttc
     4201 gggacgggag tttcgctgtt cattcaatgt ttcattgttt gtgtcaaata agatctttcc
     4261 agtagcatcc attaaagtaa tccgttcgtt cgactgatgg acgaattctt ccaaagcagt
     4321 tttgttttgc gctgcttgga ggttttcgac atctaattgc cggatcagca gttgtgcttt
     4381 ttttgtcagg tagctttctt gctgttccac gatctgctgt tgaaaataat gggaaatcaa
     4441 ttgccagcca ccaaaaaaca aactaactaa aagaataaga aagaagagac gttcataaat
     4501 ttttttccat ttcatcgttt gggttcctga aacttatagc caaatcctct aatagtcacc
     4561 aagtactttg ggtgttttgg atctcgctcg attttttctc gcaaatgact aacgtgtaca
     4621 tctacgattc ggctttgtcc tgcgaagtca aaattccaaa tgcggtctag caatgtgtct
     4681 cggtcgatca cacggtcttt tcgtttcatg aaataaacaa gtaattcaaa ttctttcggt
     4741 gttagttcaa tcagatggtc gtctacggtc acttgataat tggtcaaatc agcagtgatt
     4801 tgtccaatcg atagatattc aggctcagct tcatcttttg attgcttacg aggttcaatt
     4861 cgtctgaata ttgctttcat acgggctaat acttcgcgag gactaaatgg tttggtcaaa
     4921 tagtcgtcag cacctatttc taggccaatg atccgatcca cttggtcatc tttagccgtc
     4981 agcatcaaaa tcggtgtttc atttttttct tgacgcagcc gctgagtgat ctccatgcca
     5041 tccatcgttg gaagcatcac atctaaaatg atgaaatcaa atgattgttc taatgctaat
     5101 tctaatcctt cgcctccatc tgtggcactg gttaccttgt agccttcttt ttccaaattg
     5161 aacgtcaaga gcgttacaat agaaggttca tcatcaacaa ctagtatttt tttcattcaa
     5221 atctccttta aataggtttc attctgttta tattttagca tagaatcagt acaaagggct
     5281 attttacaaa agaaataaat ggtataatag gaaggcactt tgctgaatag aaaggaagag
     5341 cagtcaatga ttggaatcag tgcatgttta ggcggtctgg cctgtcgcta tgatggacag
     5401 aaaaaagaag taccagaatt gatggaacta gttgaaactg gagaagctgt catggtctgt
     5461 ccagaagtga tcggcggatt accaattcct agagatcccg ctgaaatcat tggtggaaat
     5521 ggattcgatg tgtggaaaga tcaagcaaaa gtatggacga caagcggcga agatgtaacg
     5581 gaagcgtaca aaaatggcgc gatcaaagcc tatcaaaaat tgcaggaaaa acacattgat
     5641 ctagtcatca tgaaggaaaa aagcccttca tgcggaaccc attcgattta tgacggaagt
     5701 ttttccggaa taaaaaaaaa tggtgccgga gtggctactg cttattttat tcagcaaaaa
     5761 atgactgtgc tctctgatga agaatggctg aaaactagag gtgagcagaa tggaaatcga
     5821 aaagaccaat cgaatgaacg cgctctttga attttattcg accttattga cagaaaaaca
     5881 aatgaactac atggaattat attatgcaga tgatttttca ttaggtgaga tcgcggaaga
     5941 atacgaagta agccgacaag cagtatatga caatatcaag cggacaagca agatcttgga
     6001 ggattatgaa aaaaaactcc atcttttttc taattatatt gttcgagaac aggtattgga
     6061 aaatatgact gcatatatta cagataagta cccggaagat aaaaaactac ttgaatatgt
     6121 acagcaaatt caagcaatcg aagaataaat aaaaggaatg aagaaaatat ggcatttgaa
     6181 agcttaactg aacgtctcca gcaggcgatg ggaaaaataa gaaaaaaagg aaaagtatca
     6241 gaagctgacg taaaagaaat gatgcgggaa atccgccttg ccttactaga agccgatgtt
     6301 aacttgcaag tagtcaaaga ttttactaag cgcgtacgcg aacgtgcggt aggggcagaa
     6361 gtgctggaaa gtttatcacc tgcacaacaa atcgtaaaaa tcgttgatga agaattgacg
     6421 atcacacttg gttctgaaac agcagagtta aataaatcac caaaaatacc aactgttatc
     6481 atgatggctg gtcttcaagg ggcaggtaaa acgaccttta ctggtaaatt agccaattat
     6541 ttaaagaaaa atgaaaatgc tcgtccgctc ctaatcgcag gggacgtata tcgaccagct
     6601 gcgatcgacc aattgaaagt attaggtcaa cagctagacg ttcctgtatt tgatatggga
     6661 actgaagtca gcccggtaga gatcgtccgt caagggatgg agttagcaaa agaaaagaaa
     6721 aacgactatg tattgatcga tacggcagga cgtctgcata tcgatgaaac attgatggat
     6781 gagttgaaac aaatcaaaga attgacgcaa ccaaatgaga ttttgcttgt tgtcgatgcc
     6841 atgactggtc aagatgccgt caacgtagct gatagcttca accagcaatt aggtattaca
     6901 ggggtcgtca tcactaaact tgatggggat actcgaggcg gggcagcact atcgatccgc
     6961 tcagtgacag gcgcaccaat caaattcatc ggttctggtg aaaaattgac tgacttagaa
     7021 gtattccacc cagatcgtat ggctagccgt atccttggta tgggggatat gctgacattg
     7081 attgaaaaag cgcagcaaga ctacgacgag aaaaaagcgg aagaacttgc acagaaaatg
     7141 cgggaaaatt cattcgattt caatgacttt attgaacagc ttgatcaagt gatgggtatg
     7201 ggcccactgg aagatctaat caaaatgatc ccaggaatga atcaagtccc tggaatcgaa
     7261 aacgtcaagg tagatccaaa agatgttgaa cgcaaaaaag cgatggttta ttctatgacg
     7321 ccagcagaaa gagcaaatcc tgatctgttg aacccaagcc gtcgtcgccg aattgctgcc
     7381 ggttctggaa acagtgttgt tgaagtgaat cgaatgatca aacaattcaa ggaatcaaga
     7441 aaaatgatgc agcaaatgtc caaaggggat atgaacatcc caggtatgga ccaaatgttt
     7501 ggttcaggcg tcaaaggaaa actaggcaaa atggcgatga atcgaatgat caagaaaaat
     7561 aagaagaaaa agaaaaaacg gaaataagat gaaaaaaaca gcttcggtac agactgaaaa
     7621 tgtctactgc cggagctttt ctatcagcaa tttttattct ttactaatac aattactcta
     7681 aacgaagagg tggcacagat gagatgtccg tggagtgaac aaacagaaag tatgcggcaa
     7741 tatcatgata ctgtctgggg tgttcctgaa tatgatgacc aaaagctgtt ccgaaaattg
     7801 atgcttgata ttaatcaagc cggattgagc tggcagacga ttttaaataa aagtgaagca
     7861 ttcgatgaag catatgatcg attcgatatc aaaaaagtcg caaattatgg agaaacaaaa
     7921 atcagtgaac taatggaaaa caaaggaatt attcgtaacc gaagaaaaat cgaagcagcc
     7981 gtccaaaacg ccaaagcagt cttgaaaatt caagaagaaa tcggcagttt ttcagagtat
     8041 ctttggtcgt tttctaatgg aaaaatcgtt gattcttctt atcattcaca agaagaagtc
     8101 ccaacaacaa gtcctctttc agatgaatta gcaaaagatc taaagaaaag aggatttaaa
     8161 tttatcggaa gcacaacaat ctatgctttt ttagaagctg tcgggatcat caatgatcac
     8221 cttgacagtt gtttccgcaa agaagaggtc gtacgtatcg gcagaaaggg cgaataaagc
     8281 atgcgaaaaa tcatatttta tggtgctata agtttagatg gctatttggc aacgaaaacg
     8341 gatgatcttc aatggctttt tgacactcca acaggtaagc aaactactta tgaagctttt
     8401 tatgaaacaa tcgatacgac catcatgggc agaaaaactt atcaggaagc aaaaaaatat
     8461 ttggagaccg aagcaattta tccagagaaa aagaatttcg ttttttccac ccacgcacaa
     8521 ttacaattgc cagatgctga ggtcgtaaac gaagatcctg ttgcttttct aaaaaatcta
     8581 caaatgacag aaggaaaaga tatctgggtt gtgggtggcg gtcgattgat caaaccgcta
     8641 ttggaacatc aaatgattga tgaatggtat atccagatta cccctgtatt attaggggac
     8701 gggattcctt tattccaaaa aggaacatat gaagcgcgtt ttgaaatgct agacacgaca
     8761 cgattcggtg aatttatcga attgcattat gtacgaaagt agaagtaaat aaaataaaaa
     8821 aggcaactat atgcagaaat gtcctgtaca tagttgcctt ttttattacc gttatgcttt
     8881 ttactctgtt aatttgttag aaaaatctag atacgcatct aaaatcgttt ggaagaaact
     8941 taatgttcct tcaacgatat taccattttc atcaattaga ttcgcaacgt ttccgatata
     9001 tgcttccggt tgctgcaagg ttggcacatt caaaaagaca agtgattggc gtagatggtg
     9061 gtttgcgcca aagccgccga tcccacctgg tgatgcagta acgactaaac ctggtttatg
     9121 atcccaaaca ctgtgtccat aaggtcttga gcctacatct aaagcatttt tcaatactgc
     9181 tggcacagaa cggttgtatt caggagtaac gaaaacgaca ccgtctagtc ccctcacttc
     9241 ctcacgaaaa cgagtccatt cagcaggagc ctgttctgga gtttcgagat cctcattgta
     9301 aaatggcaga tcatcgattt ttacaaatac actttcgtac ccttcaggaa gcaatttcgc
     9361 aaaagcttct gctacttttt tgttgtaaga atcttttctt aaactaccaa taaaaaatcc
     9421 aatttttttt gtcatacgat ttttcctcct tcaaactatc tataataatc ttacaaaaga
     9481 taagtaactg gagcaaataa aaacacttac tgacaaaagc tacatagaag atagattact
     9541 tatttttaac aaaaaagaag tctaaaatct tctattttct aaaaaaaatc gaatttaatc
     9601 aagctgtaaa gaaaaaaagc tttacagggt aaaaaaaaac tgttacacta catcttgtga
     9661 ataaaacaat ggaggtggaa ataaataatg gcagttaaaa tccgtttaaa acgtatgggt
     9721 tctaaaaaga gtccgtttta ccgtatcgtc gtagctgatt cacgttctcc tcgtgatgga
     9781 cgtttcatcg aaactgtagg tacttacaat cctttgaaag accctgcaga agtagtttta
     9841 aaagaagact tagttcttga ctggttatca aaaggtgcac aaccttctga cactgtacgt
     9901 aacatccttt caaaagaagg cgttatgcaa aaacaccacg aagctaaatt ctcaaagaaa
     9961 taaggtgacc ggatatgaaa gatttaagcg acttagtctt aacaatcgtt cgtccgctag
    10021 tcacttatcc tgatcaagtc aagttagacg tcgtagagtc gaaagacttt tacgagtaca
    10081 atctaacagt ggctcctgaa gatattggcc gtatcattgg aaaacaaggg cgtgttgcta
    10141 aagcaatccg cacaatcgtt tacggtgttc ggatcaatgc accgaaaaaa gtgcgtttga
    10201 atatcatcga tgataaggaa aagtaaataa acgtgctgta ctcgaatttt cgagtgcagc
    10261 ttttttgttt tttttattaa ttgaagaaat gattatttgg caaaacaagc aagaaagcgt
    10321 atccttatag gaggagggag tgaacagcca atgagaaaga aaatgttatt tattccattt
    10381 gctctattgt taagcgcttg tagttcggtt actcaagaat cagacaatac acatctatca
    10441 agcagtatat ctgaaactgt taccagtcca gaaaaaagta gtaccaaaac ggcttccacc
    10501 actgaacaaa caatggctac ctcaaataat gagaaaaaga ctgctttaga ccagttgaaa
    10561 gaacaacagc caaatgttcc catgcctcta gatgtaccag tctcttcagg ctatctcaat
    10621 atcgcagcga cacatacaaa gcaaggttat tctattttat attacagaac agatcgtccc
    10681 ctcgggttga atgctgacga attgaatcaa gaaacgccta ttgcaaccta tctatatcaa
    10741 tatgggtttg cttctagtca agaaacaatc caagttttgc agccatttga gatcgacaca
    10801 aatggtcagc aagtggactt aggttctcga atcacagggt atcagcaagg tgcagcaggt
    10861 tcaagttttc ttgaatggca agaaggaaac tggcgtattc gaatccgtgg gaataatata
    10921 gaaggccaag atcccttact attagctaaa gaaatcgtag cttatttgga agaaaacagt
    10981 ctaccagcac ctgaacaatt tggtaaaatt actgttgata tgggtgatac gacgaatcga
    11041 gccgtagaag taagctggca agaaccgaaa aatgcctata cgatcactca tcaagatcct
    11101 atgtctgcgt tgaagatggc agtttctatg aagaggttgt gaaatcagcg cgctgatctg
    11161 agcccatcat ttaactccaa gtcacaggaa gtaatcaaaa atagcacgcc gcatttttgc
    11221 ataattttgg cttaatacct taaaagaaaa ctagaattgc ctcttcacac atgctaaaat
    11281 aaaacagaca aaaaagaaat ggggatataa gttgactgaa tacttgaatg taggaaaaat
    11341 cgtaaacaca caaggtatca aaggcgaagt ccgtgttatc tcaacaacgg atttcccaga
    11401 agaacgttac aaaaaaggaa cggtgctaac actattccaa gacggaaaag cacctgtgga
    11461 attaacagtc aaaagtcatc gcaaacataa aaattttgac ttattgagtt ttgaaggaca
    11521 tccttctatc aatgatgtgg aaaaatatcg ggatggcata ttaaaagtgt caaaagacaa
    11581 ctctgtagat ctagctgaaa atgaattcta ttaccatgag atcatcggtc tgcatgtatt
    11641 agaagatgga actgagttag gtaaagtaaa agaaatcttg tcaccaggtg ccaatgatgt
    11701 ttgggtcgtt caacgtccga aaaaagctga tatattgctt ccatatatcg cttctgtcgt
    11761 caaagaagtc gatttagaag ctggagtggt ccgtgtagaa attccagaag gactgattga
    11821 cgatgaagat tgatgtattg actttatttc caagaatgtt tgaaggtcct atgggggaat
    11881 ccatcatcgg taaggctgta gataaaggat tattagatat caatatctct aacttccgcg
    11941 attattcaga taacaaacat cagacagtag atgattatcc atacggcggt ggagcaggta
    12001 tgctgctcaa agtccagccc atctatgata acatccaagc cattgaaaaa gctgcaccgg
    12061 atgtcaaaaa aagagtaatt cttcttgacc cagctggtaa acgattcgat cagaaaatgg
    12121 cagaagaatt ttcacaagaa gaacacttag tattcatttg tggtcattat gagggatatg
    12181 atgaacgtat ccgcacatta gtgacagatg aagtttcctt aggagattat gtccttactg
    12241 ggggagaatt aggtgcgatg gtcatgatcg atgcaacagt tcggcttttg ccagatgtgt
    12301 tagggaatca gacttcagct caaacggatt cttattcaac cggtttattg gaacatcccc
    12361 aatatactcg cccggcagaa tataaaggga tgaaagtacc agaagtattg acaaatggaa
    12421 atcataaatt gattgaagaa tggcaattaa aagaatcact aagaaggacc tatcaacgtc
    12481 ggcctgatct tttggaaaca cttgaatgga cacctcaaat gacgaaattt ttagaagaaa
    12541 tcaagaaaga agaacaagaa aaaacagcag atgaagccaa gtgacttttt ctaaaatctt
    12601 ctttacagta ggttgataat atgttagtat tttatggtga gtgcaaaagc acttaactat
    12661 tacgatattc cgctgtgaga aaagctcata agaatatttg gaataaggag aagaaaacca
    12721 tgaatccatt aatcgaagaa ttaacaaaag aacaattacg ttctgacatc ccagcgttcc
    12781 gccctggtga cactgtgcgt gttcacgcaa aagttgttga aggtactcgt gaacgtatcc
    12841 agttatttga aggtgttgtt atcaaacgcc gcggtgctgg aatcagcgaa acttatacag
    12901 tacgtaaagt ttctaacgga gtgggcgttg aacgtacatt cccattgcat acaccacgtg
    12961 ttgcaaaaat cgaagtagtt cgctacggta aagtacgtcg tgcaaaattg tactacctac
    13021 gtgcattaca cggaaaagct gctcgtatca aagaaatcag aagataaaca cggaaaactt
    13081 ccttggaaat ctgaaatttg tgaaaagtcc ttgtatatca agggcttttt cttttttctc
    13141 tatcacagtt ttaagccatt tttggctgtt ttggaccatt tttcaatcat attcccttaa
    13201 aaattgtcct agattgtccg acattgacta tcagtgtcgt caaaataggg caaaatttag
    13261 tagtcagctt gacgacaaat ataatacgaa aaataccaaa acatttaccg aatttagcaa
    13321 cttttgaacc caagtttctc aaagggtcag ctattagcaa aaaagacaaa acatgtactt
    13381 ttctactaaa aagttgatgt gataggcttc tatctaaata actattagga gtttttatcg
    13441 tgaagcaaaa tgatggacgt atcatttgga aaaatcaaag tgagttaaaa ctgattttaa
    13501 caattaatga attcatcgaa aaacacggaa ttacatctag ccgtcaatac cagaaaaagc
    13561 tatcagaaaa tccaaattct gcaccaagta tgtggttcat taacaaaaaa tatggatcat
    13621 gggagaattt attgattagt ataggacgag aaaatactgg gtatggaaaa tgggctagaa
    13681 tgtcagaaca agaattattg gaaatagtag aagcctttat taagtgcgag aagataacct
    13741 ctcaacgaat gtacgaacaa aaatcagtag ggaagaatat tccttcactt agtaccatta
    13801 aaaagatgtt aggagatata cgtccacttt ttaaagaaaa aaatgatgga tctcgattta
    13861 ctgatttcga actgctgtta gaactaaaaa atgaaataat ccgattaaaa ctacaggatg
    13921 atttatcaat gacaaagttt cgaaaactag ttcaatcccc aaaactacca tcagttgata
    13981 caattatgaa aagaacgaac aaaaattggg aggaattgat ggcagagatt ggatttgatt
    14041 atcgaagaat caaaatttat aagcagagaa acaacctatc caagacaaag aaaactaaat
    14101 agtatcactc taaatcagac gttcaaaatt aaaatttgga cgtctttttt attacccaaa
    14161 aacgaaagga gatttatttt atgaaaaagc caagatttaa gaattggcgt ttgctcgcaa
    14221 cactgagtct attatgccaa acaattggtg gatcgcttgg cccaacgatt gcctttgctg
    14281 atgaaattac tcatccacaa acggtaactg tggaattgga tttggctcac cagtatgctg
    14341 tcgaaggtac atttagcgat ggtcgtccca tgtcagaagt taccgttccg cactatgcag
    14401 tttacaatgg tgtgaagcaa gatattttct gtattgagcc aggggtgccg atttacaatg
    14461 agttcactcc tggttatgag aaaaatccat tgcctgatat gtcggagaaa gcgaaattag
    14521 tttccgtttt atggaaggaa gctggtacgg atgtggatac acatattgtg gcccagaaga
    14581 tgatttggca agaagttaat ggctacacgc ttcactcaat taaacgttct gatggtagtg
    14641 cagtaaatat cgcagccatt gagtcaaaaa tcaatcaagc cattgcggat tatcaaaaga
    14701 aaccaagctt ccataactcc acagtgaaaa ccgtgttagg tcaatcgact actgtgacag
    14761 atacgaacgg cttgaattta tcggagtttg atgaagttgt cgagaatatc gcaaatattg
    14821 attatcgtgt gaacggcaat caactagtga ttactccaaa tgccaattca aaagagagtg
    14881 gtgaattaac cctaaagaag tcagctaata caggaacacc ggtagcttat aaaatggctg
    14941 gtcaacaaac tttgatggcg ggggcaattg ataagcccaa tacctacaca atcaaaattg
    15001 atgtggaaac tgagggttct ttgaagatta aaaaagtcga taaagaaaca ggaaatgttg
    15061 taccgggaac cgttttccat ttagactttg gaaaaacatt acctgcaaaa gacgtgacca
    15121 ccgataaaga aggcattgcg acattggatg agattcctca tggcgcgaaa gtaaccatta
    15181 ctgaaaaatc agtgccagct ccttatacga ttgacactac accaatcacc gcaaccatta
    15241 aatctggtga gactatttct gtgacttcaa aaaatactcg cgaaaaaggt caaatcattt
    15301 tgaataaaat gggggtggaa acaggaactg atctttggaa cgacaaatac tcattagccg
    15361 gaaatacgtt tgccattcgc aaagacagtc caaccggtga aattgtccaa gaaatgacca
    15421 cggatgaaaa aggtcatgcg gaaacaccaa aagagattgc caatgcgttg gaattgggaa
    15481 cctattatgt gaccgaaacc aaagctagta atggctttgt gaataccttt aaaccagtaa
    15541 aagtcgaatt gaactatgtc aatcaaaccg tggctcttgt taccagtaac gtaaaagggc
    15601 aaaaccaaga aatcactggt gaaaccactt tgacaaaaga agacaaagat accggtaatg
    15661 aaactcaagg taaagctgag tttaaaggag ctgaatatac tctctttact gcaaaagatg
    15721 gtcaagcggt caaatggagt gaggctttta aaccagagtt agtgaaggga acgaaagctt
    15781 ctgatgaaac ggtgactttg actttagatg aaaagaatca agttgctgtt aaacacttag
    15841 cgattaatga gtattactgg caagaaacca aagcacctga aggatatacc ttggatgaaa
    15901 caaagtaccc tgtttccatc aaaaaggtgg atgataacga aaaaaatgcc gtgattaccc
    15961 gagatgttac ggcaaaagaa caagtcattc gctttggctt tgatttcttt aaatttgctg
    16021 gatcagctgc tgggactgcc gaaactggct tcaatgatct gacctttaaa gtatcgccat
    16081 tggaaggaac cagtgagatt acaggtgccg aagatgaagc aattacagct tataacgagc
    16141 aactaggttt tgatggctat ggcaagtttg aaaatcttcc ttatggggat tatttacttg
    16201 aagaagtaga ggctccagaa ggatttcaaa aaattacgcc attagaaatc cgttctactt
    16261 ttaaagaaaa taaagcggat tacactaaga gtgaatacat ttttacgatt accgaaaaag
    16321 gacaaaaaca accaattaaa acggtgaccg ttccttacga gaaactgacg aataaagcat
    16381 tttctgttag cttgaatcgt ttgatgctct atgatttacc tgaagaagaa gatagcttaa
    16441 cttctcttgg gacttggaaa gacggaggca aagaattgac agaccttgat tctaccgagc
    16501 tagttgataa attgagctat aacttgcatg aaatcaaaga agactggtat gtggtagcgc
    16561 aagccattga tgtggaagcg acaaaagctg cccaagaaaa agatgaaaaa gccaaaccag
    16621 tggtaattgc cgaaacaacc gcaacgttgg cgaataaaga gaaaacagga acttggaaaa
    16681 ttttgcataa attaaccgca gaacaagttt tggataaaac catcgtctta ttcaactatg
    16741 tgtatgaaaa caagaaaccc tatgaagcag gtgatgatcc agtagcgaaa gatgctagct
    16801 tgaacaatca agcccaaact gtcaattgta cggtggaacg ccatgtttcc atccaaacaa
    16861 aagcccacct agaagatggt tcgcaaacct ttactcatgg ggatgtggtg gatatgttcg
    16921 atgatgtgtc gattacccat gatgtactgg atggctcaaa agaagctttt gaaacaattc
    16981 tgtatgcatt acttccggat aatacgacca aagaaatttg gaaatctggc aaaattgatt
    17041 atgaagtgaa tgacaaagaa ttcactaaaa ccgtacttgc ggaaaaagtg gacacaagta
    17101 aatatccaga aggtacaagt tttaccttca aagaaattaa ctatggcaaa gacggaaaca
    17161 tcaatgggaa acacaatgag gatctaaaag aaaaaactca aactttaaca cctaaaaaag
    17221 ttccgacaac accaagtgca ccagaacaac cggaaatacc aactgttcca agtgactctc
    17281 aagaatctag tcctacagta aagacattcc cacaaacagg ggagaaaaat tctaatgttc
    17341 tgctgtttat tgggtttacc ttgatctttg cgactgctgg gtattatttc tggaatcgcc
    17401 gaaactaagg tgatgtgatg aaacaactaa ataggaaaaa ccaacgtgcg cgaccgcctc
    17461 ctaaaaaaag tggtcgcgct atttttgtat ccaaaactaa aaatgaaaag aggaaaagaa
    17521 gatggaattg aaatttgttg tgccagatat ggccgaaacc tttggaaaga taaggtatgc
    17581 cggcgaaggc gaagttttaa ctgaaggata tgggcggaat actacagtaa ttggtcgtag
    17641 ttatcatttg tattccagta agcaacgagc cgatgatatt gaagtggtgg tagctgcgga
    17701 agccggcgaa aaggattttg accaagatca accactaaaa gccgtgaatc cccatttggt
    17761 tgccaaaggc tatgagattg agaatcgtgg gtttaccgac tacgtgttgt atgtcgatga
    17821 tttagtgaaa gcataggagg aaaagaagat gagattaaca gaaggtattg ttgtagattc
    17881 aggactaacg tttgggaaat tacgattttc cgcattacgc cgagaagtac ggaagcaaaa
    17941 tgaggatgga acggttagta acgaggtaaa agaacggact tataatttga aatcctctgc
    18001 gcaaggtcga atgatccaag ttagtatccc agcaaatgta cccttacgcg agtttgccta
    18061 tgacgcagag gtagagttgg tcaatccaat catggatacg gtcgccaatt atgttttccg
    18121 agaaggaact actgtcaatt ggttcattaa ggccgatgat ttagtcttga aacgacaacc
    18181 agatcaggga aattctacaa accaaaatga aggaaagaaa taggtgaagc gtatggaaat
    18241 taatgttgaa catattttag attgtctcga tcaatatgga aaaggtgagc taacggagga
    18301 acaactcact aaagcattaa cctatgatga aaaaatgttt ctgattatgc atcaagggtt
    18361 actggaagta ggtaacgatg tcgaagaaga ttttgatgta ctgaattggt taggggaaga
    18421 agagtccttc tttatggtta tcgaagtaaa tgaaagtcta tgtcgagaag ccgaaaccgt
    18481 attggaagaa attggtgtgg aaatgccgga tgccattgaa gtttttttaa agcaactagt
    18541 ggaaacgaaa caactcccta tagcagtaaa tgactagcat aactgcttga aattggatca
    18601 atgaaatcct atgaagcttt tttcgattgg aggtggaaac cataaaaatg tacaaagggc
    18661 atcgtatacg ggcaggagat cagcacttgg tttatcactt tgttcttggc tggctactcg
    18721 ctctgttcat cggttggatg agcgtctttt attttcaaga gcttagacaa tttgatattt
    18781 ctaagctatc actttctact atagaaatcg ttcgttctat aaaagattta atctatttgc
    18841 taggaagtct cgttctttca ggaagcacga tgttgcttta tatacacttt tttcaggatc
    18901 attggcgcag tttgtggcat cgacaaaagc tagcccggat gattctagaa aatcattggt
    18961 acgaagtaaa acaaactcag agtgaaggat ttttcaaaga cctcaatagt agtcgaacca
    19021 aagagacaat cagttacttc cccaaaatct attaccgtat gaaggatggt ttactttcta
    19081 ttcgcgttca aatttcactg ggaaaatatc aagatcagct tttaaagctg gaaaagaagt
    19141 tagaaagtgg tctatattgt gaactagtag aaaaggaact caaagactcc tatgtggagt
    19201 acactttact gtatgatata attgccaatc gaattgggat agacgaagta gtggcagaaa
    19261 gtggggcttt gcgattgatg aaaaatcaag tatgggctta tgattcttta cctcatatgt
    19321 taatcgctgg cggcacaggt ggtgggaaga cttacttttt actcactatc atcgaggctt
    19381 tattaaaatc tgatgccgag ctttttgttc ttgatcccaa aaatgcggac ttagccgatt
    19441 taggtacggt aatgcctcat gtctattccc aaaaggagga aatttctgct tgtgtggaag
    19501 atttctatga gcgcatgatg actcgtagca aggcaatgaa agaaatgccc aactacaaaa
    19561 caggagagaa ttatgcgttt cttggacttc caccaaactt tttaatcttt gatgaatacg
    19621 tggtttatat ggaaatgtta acgacgaagg aaagtgcggt gattttgaat aagctcaaac
    19681 aaatcgtgat gttaggtcgt caatctggtt tctttctgat tctagcttgt caaagaccgg
    19741 atgcgaaata tttaggagac gggattcgcg atcaatttaa tttccgggtg gctttgggtc
    19801 gtatgagtga actgggatat tccatgatgt ttggcgaggt tgataaaaaa ttctttatga
    19861 agcgtatcaa aggtcgaggc tatgtagata cgggagggag tgtgattagt gagttttata
    19921 cgccacttgt accaaaagga tatgatttct taagggaaat tagcgacatt ggtggattaa
    19981 acgttaatac ggaaggataa aataatagta tgtagcctag gagtgtcaag aatcctgggc
    20041 tttttttacg aggtgattta tgacattttt agatttattc gctgggattg gtggcttttg
    20101 cttaggtatg gaacaagcgg gtcaccagtg tatcggcttt tgtgaaattg atgattttgc
    20161 tcgccagagt tataaggcaa tccatgatac aagtaaggag gtggaaatgc atgacatcac
    20221 aagtgtatca gacgagttta ttcaatctct cggaccagtg gatatccttt gcggtggatt
    20281 tccgtgccaa gctttttcaa ttgcgggaaa gcggcaagga ttttccgata ctcgaggtac
    20341 tttattcttt gaaatcgctc ggttcgccgc tattctccaa cctaagtttt tattccttga
    20401 gaacgtccgg ggattactca atcacgaagg aggggctacg ttcgagacga tcctccgaac
    20461 gctggatgga ttggggtatg atgtggaatg gcaagtgctt aactcaaagg cctacgttcc
    20521 ccaaaaccgt gagcggatct tccttatcgg acattctcga gacgcatgta ccgaacaagt
    20581 atttcctatc attggatcgt ctccaacatc tgatcaaaac atcagaaact tattaaatat
    20641 caacccttcc aatcgaggaa tggggggaca agtctatggg tcagatgacg tagcgcctac
    20701 cttgaccggt gatgaaggaa tcaaaatcgc attgccggta gatgatggaa tttctgtagc
    20761 gggtatgtta ctgggaaatt ttgaacaagg caatcgggtt tatgagataa ctggaacagc
    20821 gcctactttg tcaacgaaac aaggcggaac gaagatcatg cttcggaaaa acgaaacaga
    20881 atatcaagag gtgaagccag ggaacagtgt gaacctggct tttcctaatt ccacaagtcg
    20941 tcgaggccgt ctgggaaaac aaagtgtgca taccttatta acaggagacc aacaagcagt
    21001 cgtcacggat cagtatcaaa ttcgaaagtt aacacctagg gagtgctggc ggcttcaggg
    21061 ctttccggac tgggcttttg atcgagcttc tcaagtcaat tcagatagtc agttgtataa
    21121 gcaggctgga aattctgtaa cagttccggt catttttgat attgctagaa gattaaagga
    21181 ggtaaaaaca gatgatttat gatgagttga ttggggaatc tactgggtga ttggcaagat
    21241 tcagtcagat ccggaattgg aagaagaact gtaccggctc aattttgata ttcgcaaaaa
    21301 cggggtgaaa gtccctgatg atccgtatgt aattgatgag ga
//
LOCUS       DADGKS010000049        20664 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.049, whole genome shotgun sequence.
ACCESSION   DADGKS010000049 DADGKS010000000
VERSION     DADGKS010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.049"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            168..362
                     /locus_tag="JXV47_001907"
     CDS             168..362
                     /locus_tag="JXV47_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487946.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            631..930
                     /locus_tag="JXV47_001908"
     CDS             631..930
                     /locus_tag="JXV47_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487947.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1027..1461)
                     /locus_tag="JXV47_001909"
     CDS             complement(1027..1461)
                     /locus_tag="JXV47_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1487948.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1693..2403)
                     /locus_tag="JXV47_001910"
     CDS             complement(1693..2403)
                     /locus_tag="JXV47_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAX1487949.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2393..3253)
                     /locus_tag="JXV47_001911"
     CDS             complement(2393..3253)
                     /locus_tag="JXV47_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HAX1487950.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3258..3896)
                     /locus_tag="JXV47_001912"
     CDS             complement(3258..3896)
                     /locus_tag="JXV47_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HAX1487951.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3911..4210)
                     /locus_tag="JXV47_001913"
     CDS             complement(3911..4210)
                     /locus_tag="JXV47_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAX1487952.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4253..5737)
                     /locus_tag="JXV47_001914"
     CDS             complement(4253..5737)
                     /locus_tag="JXV47_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAX1487953.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5757..6218)
                     /locus_tag="JXV47_001915"
     CDS             complement(5757..6218)
                     /locus_tag="JXV47_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAX1487954.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="JXV47_001916"
     CDS             complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="JXV47_001916"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HAX1487955.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7521..8291
                     /locus_tag="JXV47_001917"
     CDS             7521..8291
                     /locus_tag="JXV47_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAX1487956.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8564..9391)
                     /locus_tag="JXV47_001918"
     CDS             complement(8564..9391)
                     /locus_tag="JXV47_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1487957.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9959..11194
                     /locus_tag="JXV47_001919"
     CDS             9959..11194
                     /locus_tag="JXV47_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HAX1487958.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12193..12453)
                     /locus_tag="JXV47_001920"
     CDS             complement(12193..12453)
                     /locus_tag="JXV47_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAX1487959.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12480..13781)
                     /locus_tag="JXV47_001921"
     CDS             complement(12480..13781)
                     /locus_tag="JXV47_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1487960.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14073..14531)
                     /locus_tag="JXV47_001922"
     CDS             complement(14073..14531)
                     /locus_tag="JXV47_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAX1487961.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14544..15869)
                     /locus_tag="JXV47_001923"
     CDS             complement(14544..15869)
                     /locus_tag="JXV47_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005227470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HAX1487962.1"
                     /translation="MKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDEER
                     NMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKIPL
                     KHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVRRK
                     YPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREIMP
                     EIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVVEH
                     TDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLNDDR
                     RRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAVEK
                     LLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15886..17298)
                     /locus_tag="JXV47_001924"
     CDS             complement(15886..17298)
                     /locus_tag="JXV47_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1487963.1"
                     /translation="MNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADDMLNIPVIGAA
                     GNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMDPEVNMGIFGG
                     IISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLGFIWPLIQIGI
                     DNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSPSKEVFRGEMT
                     RFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMGSGAGTSFIAN
                     ITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVDYLINFRIATN
                     AILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEETELGLASKNYE
                     YMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISGIIKPTEKNYQ
                     IIIGLEVTYVMAEFNKLLEE"
     gene            complement(17315..18079)
                     /locus_tag="JXV47_001925"
     CDS             complement(17315..18079)
                     /locus_tag="JXV47_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HAX1487964.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18183..19058)
                     /locus_tag="JXV47_001926"
     CDS             complement(18183..19058)
                     /locus_tag="JXV47_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAX1487965.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(19313..19397)
                     /locus_tag="JXV47_001927"
     tRNA            complement(19313..19397)
                     /locus_tag="JXV47_001927"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19361..19363),aa:Leu,seq:caa)
     gene            complement(19415..19486)
                     /locus_tag="JXV47_001928"
     tRNA            complement(19415..19486)
                     /locus_tag="JXV47_001928"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19452..19454),aa:Gln,seq:ttg)
     gene            complement(19496..19568)
                     /locus_tag="JXV47_001929"
     tRNA            complement(19496..19568)
                     /locus_tag="JXV47_001929"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19533..19535),aa:His,seq:gtg)
     gene            complement(19630..19714)
                     /locus_tag="JXV47_001930"
     tRNA            complement(19630..19714)
                     /locus_tag="JXV47_001930"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19678..19680),aa:Leu,seq:caa)
     gene            complement(19735..19805)
                     /locus_tag="JXV47_001931"
     tRNA            complement(19735..19805)
                     /locus_tag="JXV47_001931"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19771..19773),aa:Cys,seq:gca)
     gene            complement(19851..19922)
                     /locus_tag="JXV47_001932"
     tRNA            complement(19851..19922)
                     /locus_tag="JXV47_001932"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19888..19890),aa:Gln,seq:ttg)
     gene            complement(19934..20006)
                     /locus_tag="JXV47_001933"
     tRNA            complement(19934..20006)
                     /locus_tag="JXV47_001933"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19971..19973),aa:His,seq:gtg)
     gene            complement(20009..20082)
                     /locus_tag="JXV47_001934"
     tRNA            complement(20009..20082)
                     /locus_tag="JXV47_001934"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20048..20050),aa:Trp,seq:cca)
     gene            complement(20089..20169)
                     /locus_tag="JXV47_001935"
     tRNA            complement(20089..20169)
                     /locus_tag="JXV47_001935"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20133..20135),aa:Tyr,seq:gta)
     gene            complement(20171..20246)
                     /locus_tag="JXV47_001936"
     tRNA            complement(20171..20246)
                     /locus_tag="JXV47_001936"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20211..20213),aa:Phe,seq:gaa)
     gene            complement(20282..20354)
                     /locus_tag="JXV47_001937"
     tRNA            complement(20282..20354)
                     /locus_tag="JXV47_001937"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20319..20321),aa:Asp,seq:gtc)
     gene            complement(20364..20436)
                     /locus_tag="JXV47_001938"
     tRNA            complement(20364..20436)
                     /locus_tag="JXV47_001938"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20401..20403),aa:Val,seq:tac)
     gene            complement(20452..20523)
                     /locus_tag="JXV47_001939"
     tRNA            complement(20452..20523)
                     /locus_tag="JXV47_001939"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20488..20490),aa:Glu,seq:ttc)
     gene            complement(20538..20627)
                     /locus_tag="JXV47_001940"
     tRNA            complement(20538..20627)
                     /locus_tag="JXV47_001940"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20591..20593),aa:Ser,seq:gga)
BASE COUNT         6531 a         4319 c         3275 g         6539 t
ORIGIN      
        1 taagaacaat agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa
       61 ctttcaaatt gattcttttt atttatcata aagatataga tacataatca ttttcactta
      121 catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag
      181 aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc
      241 ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa
      301 agaacgagct agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt
      361 aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt
      421 atagaattag aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac
      481 catatgatta tttcaatatg tatcctggaa ttggagatct cgtagagcta tatcaagatg
      541 aatcaaatat acttgtcatt catcatgaaa tatagagact tataaaattg tttattttta
      601 taatgtatca gtatagaaag gaaataaaac atggattata ctgttgaatt tgacagtgaa
      661 ctacttaagc aatttccaca agaagaacat ttcatgtata aagaagcaat ttcccacaaa
      721 gtgacagagt atttggagca taattttttt cgtataaagc cagtgcgtac tcgttcggca
      781 aaaggaatat acgagatgaa agtcaaaatt aataaaaaaa attatcgcat agcatttgct
      841 ttaaaaaaaa atcatgtgtt cattttttat attagttcga atttgcaaaa aattgtattt
      901 gataaagagg tgagtaaaaa aataaaatag ctgagcattg gaggatagat tgagtgatac
      961 taagtctatc ctcttgtttt tctaaagaac taagctagaa ttttttcttt tgtacgttat
     1021 tatatgttat ttgtcattac caaaaagcac cttttttctt ctagtatcta tgacataaga
     1081 aataccaccc atttccttta cttgaacaaa tcctactgat tcataaaatt tttttgtttt
     1141 ctcagtatca tctgtcaata attcgatttg gactggtcca taactagtga tcttctccaa
     1201 agcttcattc aaaagcactt tgcctattcc ttggcgctga tacctcggat gaatgaggat
     1261 atcttgaata aatgcgatcg tcgcaaaatc agtgatccaa cgaacgattc cgataatctt
     1321 cccttcccca ttacgcttta tcagagattc agattgttca aatgctctag ctaaccttgc
     1381 agtgtctttt gtgtaattcg tccaaccaac gctcttatat aattcagaaa tctcatcgat
     1441 cataagggaa tcaatattca tttttttctt cctttcttat acaattctcc ctctaataat
     1501 acagttcttt gactatttaa tctatcacat ataactctcc tgtaaagatt ctctcgattc
     1561 cttaaaattc ctctttcctt ttagaatgca tactttttga taaataaaaa ggttgtgata
     1621 aattttcttc acaacctctg tttctctcta tcaagtgtta tcttttaatt ttctaccctt
     1681 accctagcat ctctattgcc cgtagtatgc atactttcca tgtttgcgaa aataatgttt
     1741 atctagtaaa tattgcggga tttcacatat attggggttg atcagctcgt tttctttggc
     1801 catcagacaa atttcatcta agatcaaact gttttctact gctttcatag gtgaatcccc
     1861 ccatgtgaac ggtccatgtc catagacaag tactccaggg acttcgtttg gatctaattt
     1921 tctttcctta aacgtctcga caatcacatt ccctgtatga acttcgtaag cttctcttac
     1981 ttcttctttc gttaattggc gtgtacaagg aaccttacca taaaaagcat cagcatgagt
     2041 cgtgccataa gctggcaaat cgcgtcctgc ttgcgcccac atgacggagt gcgtggaatg
     2101 agtatgagta atagcagtta tatcttcaaa agtttgatac aaaacaacat gtgtggggag
     2161 atctgaagat ggttttaagc tatcttcttc tattatattt cccgacaaat ctgttaccac
     2221 catttgatct gcttgcatgc attcatatct gacaccgctt ggcttaatga cgatgactcc
     2281 tagctcacgg tccacttcac tcacattgcc ccaagtcaat ttgactaatc cgtatcgcgg
     2341 caatgccaga tttgcttcaa ggacacgttg cttcattgct gcaatttttt cttcacaaga
     2401 catcatagcc agcctccttc aatttagaac ttaagtagtc ttttgcctgc tggatttctc
     2461 ttcgaaagtc ttggcttttt tcactccaca tttcaatcag aaatgttcca tcataatcta
     2521 gacgtttcaa atgtcttaat aatccaagaa aatcaacaca accgctacca aaaggaacat
     2581 cacgaaactg gcctgaatat tcttttgtta cagggtaagt atcttttaag tggatagcag
     2641 tgatataatc gatccctttc tcaagttctc gagccggatt attttccggc catgcggaca
     2701 aattgcctag gtctggatat acttgtagaa aaggtgaatg aatctgttct ttgatttcta
     2761 aaaattttga aatggagttc ataaatggat catccatgat ttccacggaa agaatgatgc
     2821 catatttaga agcttccttt acgctttctt ttattccttc gataaagtct tctctggaat
     2881 tcattgattt ctcttcataa taaacatcgt atccagctat ttggattact ttgacgctta
     2941 gattatgcgc caaatggatt gcttttttca ttagttgttt cgctgctttt ttcttttctg
     3001 gatcagcaga accaaacgga aatcgccgat gcgcacttaa acaaatcgaa tggatacgta
     3061 caccggagct gaacatctct tctctcagct cagctatctt ttcttcagac caatctaatc
     3121 gtgctaaccg ctcatccgtc tcatcaatcg acatctcgat aaaatcgaag tccatttctt
     3181 ttacaaggga aaaacgttct ttccatgaaa tatctttggg taacgctttt tcataaatcc
     3241 caatttgagc catttcctta cccccagata cgaatgatct catctttgaa gttttgtgcg
     3301 gccttcatcg gatcatttgc tgctgtaata ccacgaccag tgataaaggt atacacatcg
     3361 atcccttcaa ataagtgtaa tgtgtgtgga tttaatccac cagttacaga aacattaaag
     3421 cctagttcaa tcagtttttt gatcttcgat aaatcttttt caccccaagt ttcaccagat
     3481 aacagcgcat cacggctttg atggtagatt acctgccgga taccgatgtt atgccaatcc
     3541 atggcttgtt caaaagtcca attgccgtag agttctactt gcaattcacc tatttctttt
     3601 tgtgctgcct ccatagttgg aatcgttgca caacaaatga ctgtcatcca gtctgctcct
     3661 gcttttgcaa cattactcgc cactgttcct ccagcgtctg cacatttcgt atcagcgact
     3721 agttttttat ctgggaacat actgcgaata cagcgaatcg ctttttgtcc ttcctgtaag
     3781 caaagaattg tgcccacttc aataatatct actacatcac caactttcat aacatctcct
     3841 aatgcatgtt ctaagtcatt gtgatctaac gcaatttgca aattcggcct gctcatctta
     3901 gttccttcct ttacttgttt ttttggtacc actttgtttc agcaaatttt tcactgattt
     3961 ctttgactga catcacattt ttgataccga taactgtaac tccttttttc tctgcctgag
     4021 taaacatatt caaaaaattg actggcgtaa aaactacatc gtattggcca gctgaacttt
     4081 ttccctctga aatggcacaa tgatggattt tggtaattgg tacgtttagt tctttcattg
     4141 ctttttccac acttctcatc atcatcaagc ttgttcctga tccatttgca cacgatacta
     4201 aaattctcat cttaatccct ccattatgag tgttgtctaa tcagattttc ttttatactc
     4261 tctgcttttc tgcatatgtg tcatagtctt ctacaatcaa aaaataacca tcaggatttt
     4321 tccgatattg taactgcgga atagccaata aaccaatgac aactacggca attccagcat
     4381 aacctaggac tttcatgatt actgtaaaca atggccaagc tgttgcccag tcgaacatcc
     4441 cgatataacc accgtatgtt gacatcccaa tccatgtagc gaataatgct gaaccgccta
     4501 cttgtatgat tcctgaaaga aacgggaaca ggcaagcggc tttgaatcca cctcggttat
     4561 tggcataaac tgctataacg gcattatcaa agaacaacgg aatgaaaccg gctatgacga
     4621 tcgttggtga tttcaataaa atcagtaaac caatcatcaa aaactgtccc aaagcaccaa
     4681 acaagaaccc aatcgttacc gcatttggcg aaccaaagcc aaaagtagca gctacgtcaa
     4741 ttcctggaac agctcctggt aaaatcgtgt ttgagattcc ttggaaagat tgagttagtt
     4801 catcgacgaa tgtccgaaca cctaattgca agatcgccag atataccgca aaatttaaag
     4861 aagtcgtcat aatgtagaat aagaaactct gcccttcttg catgaattgc gcttgaatca
     4921 aataatcttt gcctagtaca atcagaatga tcccaaagaa aaatagcatg agtaacgaag
     4981 tagcaaccat attctcattg aaaatcgaca agaatcctgg taatttgata tcttcaattt
     5041 ttttgtcttg cttgattgat ctatttttct tttcatcccg ctttttcatc cactcagcta
     5101 attttgcaaa tataaagatt ccgaacattt gctgatgtgc cactgcaaat ccggcacctt
     5161 ctgtcaattc ctgcgtgatt cctactgtta agttagaagc tactgtccaa taacaaccta
     5221 aaatcagtcc cataaaaatc aatgcttgta tcctacctag atcaggaaag caaaacagta
     5281 aaatccaaaa agcggtagct gcttgttgaa cctgaacgtt tccggtagtg aaaacggaac
     5341 gcagtttcgt atatttctga aaacggacta ataagatatt taaaacaaat gcaatcagta
     5401 ataaaatcat cacatctcca aaggtacggc caaatgtctc cattaatcca gcatccacag
     5461 cattttgtcc aaaataagga tctgtaacca tggcatccaa attgaaccgt tcctttagtc
     5521 caaccaagat tggccgaaaa ttattgacca aaccaccaga gccaacagtc aaaataaagt
     5581 aaccgaccgt tgcctttaag aatccagcga tgcattcatg aagcgggcgt ttcagcaaaa
     5641 tatagcctaa taacacgata aaaccaatca ggtatgctgg ctgcgtcaag atatttgttg
     5701 caaaatacgt ccaaatgctt aacaaaaatt cccccatctt ttttctcctc tatcaattaa
     5761 ttatattctg ccatcacaac ttggtaatca tcgatggagt tcgtagagat gagacgctca
     5821 accaatccat ctgtcattaa taattcggat aatttttgga tattttctag atgttcttct
     5881 ggatcttttg ctgcgagtgt aaaaaacaaa ctagccgttt tctcctcatt ctccccttca
     5941 ctttcaaaac ggattggctg tttcaacttg gtaaatgaaa tagctgttcc aaaaacacca
     6001 tcactttttt ctgaagaatg cggcattgct acttgaggtg cgatcacaat ataaggaccg
     6061 tatttttcta cacaatggat gatctcctcc acatacgttt catcaataat ttccttatcg
     6121 atcaatacaa gacagctttc ggcgatagct tcacgccaat ccgtgatttc tttatctggg
     6181 taatgaatca attgatggtc aaaaaagtat ttcagcaaga aactcccctt ctttcttata
     6241 aaaacgacgg aaacggtgta tcattttcaa tcgagaagac atcttcaaat cctcgataaa
     6301 aattaaactc aagatcatct ttgtttgtcg gatagatgaa tttcccgcct acttgccaga
     6361 tataaggttt aaatccatac ttcaggcgat cctttttgaa tttccaaatt tcagtgatct
     6421 cttttggatc agccataaaa ttagaccaaa tatcgtagtg gacaggaatc actacttttg
     6481 cattcaatga ctccgccatg cgcagcatat caacagaagt aactttgtct gttatccctc
     6541 gtgggttttc accataggcc cctaaacaga catcgatttt gtgttcatta ccatgtttgg
     6601 caaataaatt ggagtaatgt gaatctcctg catgataaag attccctcct gatgtttcga
     6661 ataaatagtt tactgcaatt tgatccatct cctgaggcat ttttcctttt aatacctctt
     6721 ctggatcttc acaagtgacc aacgctgtcc gatcaaacgc ttctaaagct actacattga
     6781 tgtctttgat tttgactgca tcacctggct ttactgtaat cgttttttct tcaggaattc
     6841 cccatttttg ccacgtgcga accacttctt ttggcccaat gaatgttgct tcaggacaat
     6901 tttgatgaac tgctgcggct gtatggatat ctagatgatc ggaatggata tgtgtaacga
     6961 ttaaagcgtc tacatttttt atcgcaaaag gatcgattac gaaaggctga gtacgtaaat
     7021 taggctgcat attttgaacg ccactcatac gcatcatctg atggcctttt ttcatcatgc
     7081 cattcccatg actacgtttt cccgtcccac accatagatc acataaaata ttcgttcctt
     7141 catgactttt cagccaaatt cccgtacagc ccagccacca catagcaaaa gttccaggat
     7201 ccactacttc tgtttcgatt tcttcattca agtatgtgcc ccactcagga aatgtttcta
     7261 ctaaccactt ttcttttgtt acttcattga cagttttact catttgcttg ctccccccat
     7321 atcgttgttc caacttacaa gtaaatatta atgtgtatca gcatccatga aaaccctttt
     7381 atatgaccgt ttgtttttta tatgattttc tttcagtaat caatgattgt ttcagtataa
     7441 taaagacaga tatgaatgtt taaatgaaca actagtcaaa taaatccatg gatcaagatg
     7501 tccctcagga ggcaaaagtc atgaaaaact cacttgtcaa tattgaaaaa cgtcaaaaag
     7561 aaattttgga actgcttcag cagactgaac aactatcaac tttcgaatta gctgaatccc
     7621 ttgatgtatc tattagtacg atacgaagag atttaaattt attagaagaa aaaaacgaga
     7681 tcatacgcaa ttacggttat tgttcttata attacaaaaa ccagactgat tttgatcaat
     7741 ctggtcctga aaggattaaa caagcgattg ccagagaagc tagtaaatac attaacgatt
     7801 atgatacgct gtttatcaat tctagctcga ctgcgttgaa aacactggat tttcttcaat
     7861 ctaaccattt gacagtcatt acaaacaacg tgaaaatcaa ttactctccg cacaaagata
     7921 attgtagtta tattttaact ggtggagaga tgcgctttcc aaaagaagca ctagtgggcg
     7981 acatcgcatt aaatacgatt tcttcagtca atgcagacat ttgtatcatt ggctgtagcg
     8041 gagtcgatgt agtacatggg gtcacaacaa agatattaaa tgaatcaacg atcaacgaaa
     8101 tgatggtcaa caagacaatc aaatgtaaga ttttagtcgc tgatcatcga aaaatcggac
     8161 tgacatcaaa gttcaagatt gctgatattt cagtctttga ttatttgatc actgataaat
     8221 tttgttctga aaaagtatta gaggagatca gaaatacggg gataaaaacc attcaagtag
     8281 attcatttta agaaccagga cgtaaatatg taaataggat tatcaaaaaa atgaataaca
     8341 aatttatcga taaatgaaaa acacgctacg ctcaaattga taaaggaatc ccaagatgta
     8401 tccatccaat cgataccatc ataatctatt gcttctttta taaccgttat atgttgccta
     8461 aataggaatc aaacaatatc gaaaaaagga ggtatgacaa aagtcacacc tccttttttc
     8521 gaataaacgg tattcaaatc agaacactga tttcacaacc actttatttc aggtcgtttt
     8581 caatcacctt taccgcgtaa tcatttccgt tgaaacgcgc tatttttttt gcgtccatat
     8641 atctttctaa ataatcatct tctcctaatt gcttatggca agaagcaatt tcataaagca
     8701 agtattccaa tgcataagtc gatttatgtt tcttattata ctcaataccc ttctcacata
     8761 attggattgc tttatcataa tcctcgattt tacggtaata ggtggcgata tcataatata
     8821 caatgcagac catcagatta tcaaaatcag tctcactcaa tattttaagt gtacgctcca
     8881 cataaacttt cgcaaaatct aattctcctt ttgacaagta gatcattgcc acgtttgcag
     8941 ctgcttgtaa gtgatggata tctgtttcgg tcgtttgttc caacacttga ttaaaataaa
     9001 ataatgctgc atctggtttt ttcgcataaa gatgatcaag cagtccttga taaaataaaa
     9061 tttgatttaa aagatcagaa ttacttactt tttcctgatc gatcgtttgt aaaattttat
     9121 aagattcttg gtattttgat acagaattca atgattgaat ctcatttatt tttttcctga
     9181 ttttgtcttc ttctgtttct actaatatat cggagatctc gacattcagc tttttgcaaa
     9241 gcgcacttaa gatattgatg cctggcgaca tattcttgtt ttcgatattg ctgacagttg
     9301 cttgttcaca aatgccttct gctaattgta cttgtgttaa cccctttttc tttcggtatt
     9361 cttttagtaa tgctccatct actttaatca aaacaatttc cttcccttta aaaaattatt
     9421 tctcctttat atcatacaca aaaaaaagtt ctaaacaacc aaaaatgttt agaacagaat
     9481 aaaaatttta attttaaaat aatattcaaa ttaaacaact ggcgtatctg ctccttgatt
     9541 tctttttgtg ttatctgaat aattatcgtt tacagttata acacatagtg aaaattgtca
     9601 tggcgagaaa gtctaagaat atttttaaac ataactattt ctttcttacg tgtgtataat
     9661 gacgacagca cacctatcaa ttaatataat tattttattt ttttatgttc tcatgtttat
     9721 ttttaatgac acaacttctc gtatttatct ggcacaacat ataaatcgat caaaaaattg
     9781 ttgcgtgttt ttttgaaaat tggagtttca acttgattac aaaatttaaa tttagaagtt
     9841 gtgaaaacag cgagagacag tttaatattc aaaatataca taggctactc gaacgctgtg
     9901 ttttttagta tactagtaag aaacgaaggg atagactcat tccaataagg aggatttcat
     9961 gaagacaatt ctttttgctc ctgcagtatt caatttagct gagacaacac gaatgattga
    10021 ggttgccaaa gctatgaaag accgttatta ctgtgtattc tttggctttt ctaaaacttt
    10081 tgctcctttg atcacagaaa gtggctttga gtatcattta ctagcgccga tccttacgaa
    10141 aaaacaagaa gaacaaatca taaaatttga ccagttgcgt acacttaaaa acccttttac
    10201 caaagaaatg gttgcctctc gtatcactag tgaacagagt ctgattgcta agtttgagcc
    10261 tcgactgatt gtgacaggtt cgaatgtgac aattttttta tcggcccgca ataaaaagat
    10321 tcctttagta tatgttaaac cctatgcttt gagtgaacct ttttttcaat cagagcatgc
    10381 gctgatgccc cacgagttac gtttcttcgg ccctttaagc aatccccttt ggcactggac
    10441 aaaaaagcgt atagtaaata cccgatggat ccccaatgcc ttcaaacacg ctgcacaaaa
    10501 agaaatgctt cctttaccaa aaacaagttt acaaatgatg gatgctgatc taaatctcat
    10561 cacaacgcct aaactatttt tggaagaaga acagctgccg gaaaattatc gaatcgttgg
    10621 tccaattttt gctaagctca gtacttcctt gcctgaagaa gtgctaactt ttatacagcg
    10681 aaagcaacaa gaaagaaaac gtattatcta tttcgcaatg ggtagttcag gcaatccgcg
    10741 tatgttacgc aaaattttgt tcttcttaca aaaacaaccg gatctagcgg ttattgcacc
    10801 tattgactat ctgcttgatg acattcaatc tgactcagaa gatcttttaa taacagaata
    10861 tctgtctagt catcttttgc atgaattcat tgatttttct tttatccacg gcggggaagg
    10921 gaccgtccaa actgcctgtg aatccggcaa accgtttatc ggtgtgggga tgcaatttga
    10981 gcaaagctgt aatattgact attgtgtaaa atacggaaac gcaatcgccc tcacaaaacc
    11041 agtgactgaa agaaaactgc agattgctct gcgcgaagtt tcttcaccca agattcgtca
    11101 gcaggcacgc acgctgcaag ccgtttttcc aataaatggt ccacaacaag caattcaaga
    11161 aatcgaaacc ttcctgagca accacccaat atagtttcaa gtagaaaaag cttttttaat
    11221 agagactcat cagtaatttc gctattcgag acccagacag tgaaaataca aaaaaagtaa
    11281 atagtggatt gaaaagttag agttacttaa attacggtgt ctaaaaaaca caaaatcatc
    11341 cttaaaataa aagatctgac gctatccaaa tgagcatagg tagcgtctgc catttattct
    11401 tagtcaaatt ctttgacacc tttctctggt tggatcatct caacgtttct tcaaaagaaa
    11461 gaccataata attaggcaaa tacattttct taaaatgtgt catatagatc tagaagcatc
    11521 gctttgtaga gatttgtgcc gctagtcccc tcaacaatta ctaaatcaaa tgtaggattt
    11581 accactttat ctttgataat caacctccct cttctgttga gacaatgatc tcgcaatccg
    11641 atgcatactc ctatataaac tgccagcaat ccccacatat tgagtagatc atgtcagaat
    11701 gttctatgtc gtcagcaacg atacactaaa agtcacgttc accatgactg attgctattc
    11761 ccagcacaat tatttctata cacgtttcat gatttgaata aacactcaca tcatacatat
    11821 taccattcat acaccatact gcagccccta ctatatggtt gtaagctccc aaatctatat
    11881 ttgacttgat cactttggta gtagatctac taattctaaa tccattgctg ataaaatttc
    11941 cattttttcc tccttctttc tgccaaaaca gttaaaacaa taataatctt tatgtaaaaa
    12001 agggctgtga caaaagcctt gtcacagtcc catattccga ataaacggtg gtcaaaagct
    12061 tgcatctgcg gtaataagtt caaccaaacg aaaaataagc caacatttca caaaaattta
    12121 agaagcaatt ttcgtaaatt tcttcttatt tcttgaagct aaccacttct gttacaacca
    12181 cttttagaac atttaaagct tcgatgtgac aaaccatcta tgctgctcga tcataaaatt
    12241 gatagcaaaa attccacaaa gtacatatgt cccccatgaa aacaaaacat tcatatgcgg
    12301 tacaatgatc tttggaagaa tcacgatcaa aaatgatgcc agtgcccaaa tccatcgatt
    12361 gatttgaata tgatatgtag ctagcatatt caatataagg tgactagccg ttaataaaaa
    12421 gataaaaaca aaaaataaaa tcagccaata cattgtttcc caccttctaa aaaccaaact
    12481 tagacagtct ggacttcgtt ttctccacga ctttgttcat ctgacagcat ctttttatca
    12541 taagctttta caaatggata atagataata aatgctatca atgtgttgat catgatcaag
    12601 ataacaacac gccagtcatt tcctgctgaa agataaccgc cgattggagc tggtaatgtc
    12661 catgttggca aaacagtaaa tctattgacc atttctaatt tgactgcaaa ataactgata
    12721 atagtcaaaa ctaaaggaac taagttgaac gggatgaaca tgtaaggatt caacatcata
    12781 ggagctccaa aaattatggg ctcattgata ttgaagatac caggaataat agaaaaacga
    12841 ccaacctctt tcaagaattt tgatttacag aagaatataa acaaaacaga taccacgatc
    12901 gttgctcctg caccaccaat tgttaccgtc cattgataaa actgttcagg agcgatatag
    12961 ggtaattggg tggcagctgt accatctgcc aatgcctttg cattctcatc caacatgatc
    13021 agccacattg gacgaacaac agcccctaca atactcatgc catggatacc aaatgaccac
    13081 aacaaatgga tcaaaaacat tggtagtaaa acaccaagca aattattccc taaaatattg
    13141 gttaaaggct cgaataacga taataaggca gcgtttacat caaagcccgc gacgcttcga
    13201 atcagccaag taattgttaa aatgactgca cctggaatca atgcctcaaa actacgggca
    13261 acagcaggtg gcacttgttc tggcattttg atagtaatat ttcgattttt aaagaaacga
    13321 tatacttcca ctgcaaaaat catagataag atccccgcaa acatcccaga tgctcccaaa
    13381 gaactcatag gtaagaccca gccaagaggt gcctcttcag gagttaaaac gtttacagga
    13441 acttgtaaca taaagaacgt tcctaaagat aatataccac ctgtcacact atctaatcca
    13501 tatgatttag ctagatccga acccataaca aaagttgcat aaatagccat caatcccatc
    13561 gtcatcctaa agggtaaaac aatcgttgcc gaataagggg caataaattc attccatcca
    13621 ggaaacggta aattgataaa gaccataaaa aatgtcccaa tcaaaatcaa tgacaatgtt
    13681 gaaacaaccc cattacgaat tgctaataaa tgacgctgtg taccaatttt tgccattggt
    13741 gggacaagtt tctcttcgac ccatttcatc agcttttcca ctaaaaccac tccttttcaa
    13801 taaaatatga accattcatt gcatgacaac gcaaagaatg ttcataacta attatataat
    13861 taagaaattt tatttcaata tattctctta aataatcaaa tttattttta agaatcctga
    13921 aaataagttt tctaaatcat aggagcaaca aaaaaattcg ataattaaca aaaatcaaaa
    13981 tgattaaatc tagtgattga aacatatcat ttcaaaaaaa ttttgtaaat tcacccataa
    14041 atatcaccct atttaacttt tttcatcgta cactaaaatt caaaacaact atctttaatc
    14101 tttacttctt ggttttgttt taataaattt ccttcaaaaa tgcctggaga aactacaatg
    14161 atcaccgtat ctttttgtgc ttgctccaac ttcttcaaat ctataatagc taacagtgtc
    14221 ccttctttta cctcctggtt actttcaacc cgtatctgaa acggacttcc ttcgagttca
    14281 actgtatcta aacccatatg gatcagtatt tttctgccag attcactttc gatcgttatg
    14341 gcatgtcggg taggaaatat attatcgatt attcctttaa ctggcgcatg gatatatcca
    14401 tcatgattcg ttatagcgta tccaactcct atcatttttg aagaaaagac ctcgtctttt
    14461 actgctgtta atggaataat ttgaccacta gctacagctt ttagaatgtt tcttgtttta
    14521 aagaaatgca ctttttatca cctctacttt aatgctggcc aatatttttt gtttactttg
    14581 atcatttcat ctagtatttt ttttgcgact ctggcatttg gtacggtttg attcaatgta
    14641 aatgcttgta aagctttttg ataagaacct tcaaagtaag catctactag taacttctct
    14701 actgcaactt gtgcctccat caatccttta tgaaaatcac tgattggttt tcttagtgta
    14761 attggctcca caccagttgc accaacatat gccggtattt caacaactgc atctgaccgt
    14821 agattcggaa tcgccccttg attaggaacg attagcataa agcgacgacg atcatcattc
    14881 aacaaggaaa tagctatatc gacgatatat tgtccatgct ccccaaaatt aaagttcaat
    14941 acttcttcca caataccgcg gcgtatttta tcagccattt ctttggtatt tttctctcgt
    15001 ccatccatga ccatattagc acgtgtatac tctttgtcag tatgctcaac gaccatatca
    15061 ggatataagt aatactctaa gtaattattc gggatattac ttggaaaatt tttcgtgatg
    15121 actgacatca tttgaaaggt tttttgccaa gttttatctc ctatattaaa atcggcgact
    15181 tgcatttctt ttgttattag tttttcaata atctctggca taatttctcg ttgcaattct
    15241 ttatcataaa tcgatgtata ccagccaaag tggtttaaac cataatacgt aacgatccaa
    15301 ttcttacgat cataaccgta attcactgca atcgtttctt caattgaaat agtcatatca
    15361 caggcattaa tcatttttac attcggatat ttacgacgaa cagcttcaga aacgatcgac
    15421 tctggatttg tataattcaa aatccatgct ttgggggcat agtcttgtat atgatcgaca
    15481 atttccaata aacctttgat tgagcgcatc ccataagcaa atcctccgag tccacacgtt
    15541 tcttgtccta ctaatccatg tttaagtgga atcttttcgt ccttttctcg catctccaat
    15601 cctccaacac gaatttgtga gaaaacaaaa tcgcatcctg taaaagcaag ctttggatca
    15661 tccgttgcac gaatgcgaat atttgaaaaa ccttttcttt tcagcataaa tttaacaatc
    15721 aagtacatat ccatatttct ttcttcatca atatcatata aacgtatttc agataatggc
    15781 aaccgttttt cattgttcaa aatggcttga acgattcctg gtgtatacgt actcccgcct
    15841 ccagctatag tgataatctg ttttttcatc atcatctttt cctttctatt cttctaataa
    15901 tttattgaat tctgccataa cataagtcac ttctaagccg atgataattt gataattttt
    15961 ttcagttggt ttaatgatcc cgcttatccc taattgcttg attcgctgtt cctcgaccat
    16021 ggtgggatcc actacctcta cccgtaggcg tgtattacaa ctatagacat ccaggatatt
    16081 ggcttttcct ccaaacgctt gtagcatttt tgttgccata tattcataat ttttacttgc
    16141 taaccctaac tctgtttctt ctaaggttac ttcattgcca aactctgcct tagcttcacg
    16201 tcctaatgtc tgaatgtttc tcttattgat caaataataa aaagtaacgt aatacaaggc
    16261 aaaaaagaaa attccgattg gaagaatcaa aatagcattg gtagcgattc gaaaattgat
    16321 gagataatca acaatacatg ctccgaatgt aaaaccaatt cgtatattga ataagtaaca
    16381 gacaatccct gctaaaccgg caaaaagtgc atggatcacg tacaacatag gagaaagaaa
    16441 catgaaacta aattcaacag gctcagtgat atttgcaata aatgaagttc ctgcaccgct
    16501 tcccatgatt cctttgacca tctctttatt ttctttataa gctgctttat agatagctag
    16561 acatatagct ggtataccaa acatcattac tacaaaaaaa actgataaaa acagtccagc
    16621 ctgaggatct ccgttgataa agcgtgtcat ctctcctctg aaaacttcct tgctaggaga
    16681 tgtatagctt cctaaatcgt aataaatata cgtattcaac acatggtgca gtccaaaggg
    16741 gatcagcaaa cgattcaaaa acataaatat ccccacacct aatgctccca tatcaacgag
    16801 cagttttgca aaattatcaa tcccaatttg gatgagcggc cagataaagc ccaaaaaaac
    16861 agctgcgatt gtttgtagaa tcatcaccat agtcaatggg aatttttcgc ccgcaaaata
    16921 agaaaaaact actggtaatt tttgttcttt aaagcgatta tacgtccatg ccgctactaa
    16981 accggaaata attccaccaa aaatccccat attcacttct gggtccataa tttctaagcc
    17041 ttttttcaag gtagcaatcg ctaaaaaacc agtaagtgca ggtattcctt tgtccttatt
    17101 tttgacaaaa ccgattgcaa ctcctatagc aaataagata tccaagtttc caaaaacggc
    17161 atttccagct gcaccaatta ctgggatgtt cagcatatcg tcagctgata aacgcatgat
    17221 caatcccgct aatggcatcg ctgcaactgg aagtagcatc gctcttccaa gcttctgcac
    17281 atttgattta acattcattt ttattcctcc tctattaaat atcctcatat gttactaact
    17341 caatcaaagg atcatttttc actttttgag caaatgctga atgaattaaa aattcgactt
    17401 ggtgggtacg aggatacaca aaacttgaac catttaacaa ttcctgatcc aaatacgctg
    17461 cgtgacacat gacttcgatc gttttatctt ctctcaatat catgagtaaa cttgccaaat
    17521 attcttccac actcgtattg atttgtcgtt ttttttcatc agtttctcct acgacatcga
    17581 aacaaggctc aaaataatcg acatgacgaa cttcatcttt tcgttcaaag ttgctccgaa
    17641 ccggcaaatc atattttttt gctaatgtaa caactacctc ctgattttca tccaaagtat
    17701 gagtatgatg atgactgtct aaatgagttg gtatgatccc cgcatgataa attttttgaa
    17761 tctgagcatt ccattcctga tacagttgat ctttgtcaat gttaaatgga tgctgataat
    17821 aagataagga tctgaactct ccgctttcga taagagtatc gacagttttg aggagtggtt
    17881 tgccacacgt caatgttaaa tggactccta cacctagcct aggcatttcc tttcttagtt
    17941 tcacagcatg ctcgaaaccc ggcatatttg ccatcaatgt agttgatgtc aaaattcctc
    18001 gctgataagc atccataatc ccataattca caccatggct atagccaaaa tcatccgaat
    18061 taaaaatcac ttttcccatt tcattctcct tcttttttct actaaaatag gcgcaaccaa
    18121 ataatcatag tccatttact atgtgtcatt tggttgcgcc tatagatagt tacgccctta
    18181 ttttaataga ttcttgctag atgaattgcc aaatagatga tttcattttc ttgaatggca
    18241 agttgaaatt gctgttcgat gatatcttta atctttagtg ctgtacaata cgctttgcta
    18301 tgtttaaatg tttcagtaaa aaaaccaata ttttctactg gcgtttcttc ctgataaatc
    18361 aagcgtttaa ccaggaattt gatatgaacc attaagcgat gataagtcag tgattcttta
    18421 tcataaacgt ttgaatagga tttttctaga tgggacaaaa tcgtggtcgt catttctact
    18481 atttttaagc tctttaaact attaggctct cctagctcag cattaatgat atgcatagtg
    18541 atgaatccta cttcatttga ccctaactcg gtttgatatc gatgattgat tcgctcgacc
    18601 acttctactg ctatatcata ttcatttgga taaaggaatc tcatttctgg caacataatt
    18661 gctgtgacat ctctatcttc tctttttcgt tgaatagcaa aataaatatg atctgtcaat
    18721 gtaatataga tatttgaatc taatggagag gagatcctag ctgttatcag ttcaatcact
    18781 tcttccgcaa aatccataaa ttcgattgga atctgcgaga ctatctcact gaatcgtttg
    18841 atcttttctt tagaatctaa tacaaataat ttgtcagcat cctcaacatc aaatggctta
    18901 ctcactttag cagaaaagcc aatccctttc cccatcgcaa ttttttctat tccatcgtca
    18961 tcgatcaata cagcattatg attcagcttt ttcatcacat acaccgttaa ttcacctcct
    19021 ctatatgata aaacaaaaca acttgcagac tccttcatac atatttttgt ctccaaacaa
    19081 tttttaaaga caaaaaacga cctaagaaag aaccctttct taggtcgtgc ctaattgaat
    19141 agtagcaccc tacataattt acaaaaatag tttaacacat aataaaagcg ttatcaatat
    19201 cttttttact cgttttatga taatacttgt atcgaattga tttggaggta attacataaa
    19261 aacaaaaaaa atatagcaac tctctataag aaagttgcta tattgataat tataccggcg
    19321 gccggggtcg aaccggcacg tcctcaacgg acactggatt ttgagtccag cgcgtctgcc
    19381 aattccgcca cgccggcaaa tttaaaaata ataactgggg tagctggatt cgaaccaacg
    19441 catgagggag tcaaagtccc ttgccttacc gcttggctat accccaagaa taaagggcga
    19501 atgatgggaa tcgaacccac gaatgccgga gccacaatcc ggtgcgttaa ccacttcgcc
    19561 acattcgcca tcataaaaga tgttatttaa tttctcaata aaaaactaag atgaagacat
    19621 cttagtcaat accggcggcc ggggtcgaac cggcacgccc tcaacgggca ctggattttg
    19681 agtccagcgc gtctgccaat tccgccacgc cggcaagttg atttattagt actaaggcgg
    19741 taaccggatt tgaaccggtg atgaaggttt tgcagacctc tgccttacca cttggctata
    19801 ccgccattat actattatca atctataaaa taaagaataa attatagaaa ctggggtagc
    19861 tggattcgaa ccaacgcatg agggagtcaa agtcccttgc cttaccgctt ggctataccc
    19921 caagaataaa aagggcgaat gatgggaatc gaacccacga atgccggagc cacaatccgg
    19981 tgcgttaacc acttcgccac attcgccatg gcaggggcag caggaattga acccacacta
    20041 acggttttgg agaccgctgt tctaccttta aactatgccc ctataaaatg gaggagagtg
    20101 gattcgaacc actgaaccct aaggaacgga tttacagtcc gtcgcgttta gccacttcgc
    20161 tactcctcca tggtggcgcg ggacagaatc gaactgccga cacacggagc ttcaatccgt
    20221 tgctctacca actgagctac cgcgccatat tttaaaatta ttaattgaat aacaagaacg
    20281 acggttccga cgggaatcga acccgcgatc tcctgcgtga caggcaggca tgttaacccc
    20341 tacaccacgg aaccagttca ttatggaggt taacgggatc gaaccgctga ccctctgctt
    20401 gtaaggcaga tgctctccca gctgagctaa acctccaaca ttcaattaaa atgacccgta
    20461 cgggattcga acccgtgtta ccgccgtgaa agggcggtgt cttaaccgct tgaccaacgg
    20521 gccaggtaaa tttgctacgg agagtaaggg attcgaaccc ttgagacagt ttggcaccat
    20581 ctacatgatt tccaatcatg ctccttcggc ctctcggaca actctccaga gtgaaagaag
    20641 ctcaatactc tttctcaaaa tgag
//
LOCUS       DADGKS010000050        20395 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.050, whole genome shotgun sequence.
ACCESSION   DADGKS010000050 DADGKS010000000
VERSION     DADGKS010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20395
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.050"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(383..1849)
                     /locus_tag="JXV47_001941"
     CDS             complement(383..1849)
                     /locus_tag="JXV47_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAX1487966.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(2140..4224)
                     /gene="cadA"
                     /locus_tag="JXV47_001942"
     CDS             complement(2140..4224)
                     /gene="cadA"
                     /locus_tag="JXV47_001942"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAX1487967.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKKFMQYIASAEQFSTHPIAQSVLEGYAGPLLP
                     TTNIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPLSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKKEDE"
     gene            complement(4366..4545)
                     /locus_tag="JXV47_001943"
                     /pseudo
     CDS             complement(4366..4545)
                     /locus_tag="JXV47_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308695.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
     gene            complement(4749..5108)
                     /locus_tag="JXV47_001944"
     CDS             complement(4749..5108)
                     /locus_tag="JXV47_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HAX1487968.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(5138..5479)
                     /locus_tag="JXV47_001945"
     CDS             complement(5138..5479)
                     /locus_tag="JXV47_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487969.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERVDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            complement(5476..6150)
                     /locus_tag="JXV47_001946"
     CDS             complement(5476..6150)
                     /locus_tag="JXV47_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAX1487970.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     KFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(7326..8624)
                     /gene="asnS"
                     /locus_tag="JXV47_001947"
     CDS             complement(7326..8624)
                     /gene="asnS"
                     /locus_tag="JXV47_001947"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HAX1487971.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(8664..9854)
                     /locus_tag="JXV47_001948"
     CDS             complement(8664..9854)
                     /locus_tag="JXV47_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAX1487972.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(9875..10402)
                     /locus_tag="JXV47_001949"
     CDS             complement(9875..10402)
                     /locus_tag="JXV47_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAX1487973.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(10449..13238)
                     /locus_tag="JXV47_001950"
     CDS             complement(10449..13238)
                     /locus_tag="JXV47_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAX1487974.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(13385..13585)
                     /locus_tag="JXV47_001951"
     CDS             complement(13385..13585)
                     /locus_tag="JXV47_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAX1487975.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(14038..14358)
                     /locus_tag="JXV47_001952"
     CDS             complement(14038..14358)
                     /locus_tag="JXV47_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487976.1"
                     /translation="MKKRLLWCLLSLSLSLTSQPVFAEETQRFPITGTRLYKNVYVQT
                     PDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(14861..15979)
                     /locus_tag="JXV47_001953"
     CDS             complement(14861..15979)
                     /locus_tag="JXV47_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1487977.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            16450..17757
                     /locus_tag="JXV47_001954"
     CDS             16450..17757
                     /locus_tag="JXV47_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HAX1487978.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSVT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETARLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAE
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            17878..19077
                     /locus_tag="JXV47_001955"
     CDS             17878..19077
                     /locus_tag="JXV47_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAX1487979.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYSSTWTFAVI
                     LTYFVVLEIFYSTFYFLIPLVFFSIFAFSYFSEKRRLLNGLLFNIFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVFLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCIPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYWAQSRATLNPPILLMSGGQGADEKVPE
                     AMAMKQYAMEQGIPERDILVETNSTTTLENMRYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(19104..20372)
                     /locus_tag="JXV47_001956"
     CDS             complement(19104..20372)
                     /locus_tag="JXV47_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HAX1487980.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVRKGILFLPIVKRMKEKNKV"
BASE COUNT         5902 a         4344 c         3559 g         6590 t
ORIGIN      
        1 aatggtgttc aatcagctga ccttcagcat tagctcaaaa agcggcaaaa tatgaggagc
       61 tatttttccg tttgtttctc taatactcag gtcaaatcgc tgattttaca acctcttcct
      121 taaacggtgt tccaaagctt gcatctgcgg taataagccc agccaaacga aaaatatgag
      181 gggctatttt tgtttggctg ttcttattac ttgatgcagg acagcttttt cacaacctct
      241 gattcacggt gttccagaag tagcttcttc gaaaaacaag ccgaaacttc acaaaaattt
      301 gagaagcaat tttcgtaaat tccttcttat ttcttgaagc tgaccacttc tgtcacaacc
      361 tcttgtaaca agtatttcta ttttaaggct gaaccactgt ttctggttca gtgatttctt
      421 tgtttttgtc tcgacgagca attgctggca agatcatacc taataagatc aagacgattg
      481 gtgtgatgat attcgtaaat aattggaacc accatgcttt aggatcagca gtataatcta
      541 cttttggcac cattcctagg atacatgcaa acgcagtgaa ggcaaagcac caagcaccaa
      601 agataaaacc gatttttgga tttttaacaa atttatattc agaattgaat ttcttataag
      661 ctttattcaa catcatatat gccaagaaca cccataggta acgcattggc atgacaactg
      721 agttcaagtt cgtcaaccat tttactaatt cattcatatc tttgatacca aaaatcggca
      781 acaaaataat gattcctact agtatacctg tcagaagata accattcacc aatgtacctt
      841 tacgattacg tttacgtagc cagtttggta caaattctgg atccgcatct gctaacaaga
      901 tttttagtgg tgcatcaatt gaaaaggcta atgcggagat ttgtccaatc atgtttgtca
      961 atgcgtaaat gatcatcaat gagttaccga taccatagta attacctaaa atttgaaaag
     1021 cactgtatgc cccatttgcc atcaagtctt taggaatatt atcactagca aacagcatac
     1081 ccattgcgac tgagcctaat acagcacaaa tccctaccat tgctgctaag aagatcatcc
     1141 ctttaggaaa ttcctttgca ggatttcttg tagagttgac ataaggggat attttttccg
     1201 cccctccaac tgcaaatact agcatcgaaa cggttgtgaa ataactgaaa tcaaatgttg
     1261 gaatatatgt tttcacttga ttcatatgtg gtgtggcaaa ttccatcgtt ggattgatga
     1321 acggtgccgt tacagctaaa agaataaata agatcgacat gacgaacatc gctgttccgg
     1381 ccagtccgcc aatcactttc aaagtagaaa gtccttttgt tgataaatat aaaaaggcaa
     1441 gaaatataat aagtgaaata actgctacca tttgtactga catcgtattt acgatatttc
     1501 catttccttg gactgcccaa ccaccagcaa tcagaattgc ttgaggcttt tgtgccaaat
     1561 aaggaatatg gacgacccag taagtccaag cggcatagta tgccagtcgt ttattagatg
     1621 tcgtattttc gacccatgaa ctgacgcctc ctttactatc cttgaaggct gatcctaatt
     1681 gtccaacgat caatgcgtat ggaataaaat aaatggccaa aatcaatagc caagaggtga
     1741 caactgatac tccttgctga gcatagttat taactacatt ccccatgccc caaaccatgt
     1801 taaatgcaat taacgcaaca gtaaaccagc gtaattgttt gttgttcatt cgttctctcc
     1861 tttatgataa aaatttgtta tccagatgta atcatattca atttttaaca aacttacaag
     1921 acagtgttat tttatgtgtg tattctttta tttaatacac atcgtttttt catatttttt
     1981 ccatcaaaaa aataagttat tttcttttat ttcattgacc ttattgaatt tcaagctatt
     2041 ttgaattttc tgcaaaatta aaaacattag ttattttata atcctatcta ttttctttac
     2101 atttttcatt aagaaaagga tataaaaaaa agaggacgtt cattcgtcct ctttttttac
     2161 atgcaagctt cgcatggcat tcaaaacagc taatactgtc accccaacat ctgcaaatac
     2221 tgcatctccc attgatgcaa aaccaaaagc acctaaggca agtaccaaaa tttttatccc
     2281 aatagcaaag acaatgtttt gtttgacgat tttcaatgtt ttctttgcta aatggattgc
     2341 ttctgcaatc ttcgatggtt gatcattcat gatgactaca tctgctgctt caattgcagc
     2401 atcgcttccc aatccaccca ttgcgattcc tacatctgct cttgctagca ccggtgcatc
     2461 gttgattcca tctccgacaa atgcggtctt tttattgttt ctttgtaaga tttcctctaa
     2521 ccgctgcact ttatcttcag gaagcaattc gctatatatc ttgtccacgc ctacttgctt
     2581 cccgatatga tcagcaattt ttttcgagtc gcccgtcaac atgactgtgt tcttcacacc
     2641 agcctgtttt aattgaacca atgcgtctac ggcatcttct ttcaaggtat ctgcaataac
     2701 aagataacca ctgtaacttt gatcgatcgc tagataaagc aatgtaccga tttcttgact
     2761 taaaggaaaa gagatttcaa atctttccat caatttgtga ttacctgcta atacttgttt
     2821 gccatcaact tcagctaaga tcccttcacc tgcaaattcc tggatattag ttgttggtaa
     2881 aagcggacct gcgtagcctt ctaaaacaga ttgagcaatc ggatgtgtag aaaactgttc
     2941 tgcactcgca atatattgca tgaatttctt tggatcgatt tttgtatcga tcgtctggat
     3001 cgaaaagtca cctttcgtta atgtgccggt tttatcgaat accactgtct cggtttgcgc
     3061 aagcaactcc aagtaatttg aaccttttac taatacaccg attttacttg cgcctccgat
     3121 accgccaaag aaactaagtg gcacggaaat cactaatgca catggacatg agatcactaa
     3181 aaatgtcaat gctcgataga tccattcaga aaacgccgct ccagaaacaa caagtggagg
     3241 taaaacagct aataaaacgg ccaatcctac aacgactggt gtgtaatagc gcgcgaattt
     3301 agtaatgaaa ttttcagctg gtgctttttt actgctggca ttttctacta attctaataa
     3361 tttgctgata gtagaatttt cataagattt ttctacttga actaaaaatg gtttattttt
     3421 attgataaat ccgcttaata ctgtttcacc aacatataca gatttaggga ctgattctcc
     3481 tgtaagtgct gacgtatcga ctaatgattc tccttcgatg atcgttccat ctaacggtac
     3541 acgttcacca ggcttcacaa gtacaaactg accgatctgc acgtcttcag ggttcacggt
     3601 catcaatcct tccgtcgtct gcacgtgagc tgtttctgga cggatcgcca tcaattcgcg
     3661 aatcgatttt cttgaatgac tgactgccaa tccttggaaa tactcgccga tttgataaaa
     3721 tagcatcact gctacggctt ctggatattc accgatcaac atagcgccaa tcgtagcaac
     3781 agacataaga aaattctcat caaagatttt tcctttgacg atattcatca ctgccttctt
     3841 cactacatca tatcctatca gcagataaat caataaatac cctatcaagc gaattggttc
     3901 attaaaatca aataatagca ataaagcgat acctgcaagg gaaaataaaa tccggaacag
     3961 cgtatttctc tctttttcat ttccatgttc agatactttt tccttatcta tttctgttac
     4021 tttgacatct ggttctaatt ccttcactac tttttttgtt tcttgttcaa tcgtagccaa
     4081 atgatcttcc tctgcgtcaa tcgttagttt tccagaagtg aagtttaccg ttgcttcctt
     4141 gactccattg atcttctgaa ctcctttttc gattttcatt gcacagttcg cacaatctaa
     4201 accttctaat ctgtaacttt tcattttaat gacctcctcg cctcaacata tgaacatctc
     4261 ttcataacta attataaatg aatggttatt catatgtcaa ggtatccgaa agaaaaaatg
     4321 aaaaacatct gcatcggaaa atttcttcca tacagatgtt ttggcttatt ctttcttttt
     4381 ctcttcgatc attgcccctg ctcttatcca acccgcactt gccttcttga tcttgacagg
     4441 atagcaacta agtttgaagc ctgttgctgg caatttgtct aaattcatta atttttcgat
     4501 aggacaatat cttttttcaa tccctgcaaa atgtccttcc cagatattcg aagctccact
     4561 acgctttcaa aaatatagaa agagttcttt aatgaaaatt atttcaactt tccataaaca
     4621 gtaatcccat ataaataaaa gacgtaaaag tcacatggga gaacttatac aggaaaacac
     4681 atagagtcag gtgaaataca tgtatcccac ctgactctat gcgttttcta acctttatta
     4741 ttctcttttt atacaatttc tgcaccgaat ggcatcaacg ccaatcgagc aagtttgaaa
     4801 gattgcttgg caaaaggtat ccctatgatc gtgatacata gaaggatgcc gctgacgaca
     4861 tgtgcgagag caattggtag gcctgaaacg atcagccaga tgatattaac gatcaatgac
     4921 atgccagact ggtgataaat tacttctttg ccaaaaggcg caaaagaaag ggaggcgatc
     4981 ttaaaacatt gcataccgat tgggatacct atgatcgtga tacaccaaag tatccccgct
     5041 gctaaccagc taagaccacc gattagtccg ccgaatataa accagatgac atttcctaaa
     5101 caactcattg tatttctcct tctattactg tttttgatta aaactgggca aaaattgatt
     5161 ttattcttct ttttttagct tccagcatca agtattctgc aaattttttt tggatttctt
     5221 ccgtattttc ttttgttact aatgtgtgtt ggattagttt tcctgatggt cgctgatcca
     5281 cccgttcttc tgactgttgc acgtccgctt gcgcaaatcc gataatccgt ttttcttttg
     5341 ttacagcaac gagcaatagt ttattcttat catttaggtc agctgccgtt tttgctttta
     5401 cgaatgattc tggatgatca gtaatcagct gattgatttg aggtaaatct tcttttactg
     5461 cccaccgtat ttccatcatt tctcactttt ctttcgctca tttttatctc cactaaaaaa
     5521 atcgactgcg gcaattgcat ctatccagct ttgtgcaatg atctcatgtc cgccaatcgt
     5581 tgggtggacc ccatcttctc ttgtatattt cgaaaaacca taagcaatcc ctaaagcatt
     5641 gaatatgcca tctaaaggaa ccagcaatgc gccatattcc ttagcaagtt tacgaacaat
     5701 ttggatttta gggtctaagt ctttacgcca gccatgacgg tcgtcggtta taggaagtac
     5761 aaacggctcc atcaagatga tgttgcagat ttccgctgtt tgaagttcat ttagtaattt
     5821 tcgataaacg gattcaaatt gctgcgcaga tttctcagtt ccgaatatag cctgatcgct
     5881 agtattatgc caggtatcat tgattccgat caaaatcgat acatagtcag gttgtaaagc
     5941 taaacaatct tcttgccagc gtacttgcag atctgcaatt ttgtctcctc ctatcccacg
     6001 gttcatgcat tcaaatttca tcgttggata ttgggagatt agttttccgg caatcaaaag
     6061 tggataacct ttacctagat cagttgcttc tgctcggtct cttcctgcgt ctgtaatgct
     6121 gtcaccgata aataatatac gttttttcat ttgtcaaaaa ctcctttttg aataaaacga
     6181 tgattttctt ccttatatta tcccataagc cctatcaaga cgaaagagaa aatatatgta
     6241 taaaaaatga caccagccta gtcccttcaa tcaattgaat gaacgctcat caagtgtcta
     6301 gttttttata ctttttttct taacgtgccg gattcccctt gattccttcg ttgtttggtc
     6361 cagagaaatc gatcacacct aagcttccgt caatcagacc actgatgacg ccatcagaac
     6421 atatatttat aggctcatct aagacttcca gtaaatgttc ttttactaat atctcttcta
     6481 gattgcttgg gatagattgg tcataacttt atctggtccg atgatttcaa ggatgaatta
     6541 aacttacata tggatcattg catgctgaaa atacggacct actccatctt cgaatgttac
     6601 tattagtttg ttttcaggta ctagatgctg ctttatttca acagcagaag catcatcaaa
     6661 tcagatttcc atttgaataa ccttctttgt atatgtttga ttgattgcga tttcgttata
     6721 gaaccttgtg aatcaaatag caatttcttt tgctttcttc tcttgtctgc tggaaacttc
     6781 ctttatcccg tattttaaaa aaagaactgc gagagttcgc agttcttttt tttaaataaa
     6841 cgttgctctc cggccaactc ctcggtcaca agtcacaata gtcatcaaac atgaaaaact
     6901 gttttttgaa attactcctt gtgactcgga gctgaacggc aggcgcacaa cctcttgata
     6961 taaacggtgt tcaatcagct gaccctcgat attagctaaa aaaacggtaa aatatgagaa
     7021 gctatttttc cgttttgttt ctctaatact caggtcaagg cactgatttc acaacctctt
     7081 ccttaaacgg tgttcaaaag ccagtttctc ggtattaagc caaatttatg caaaaatgtg
     7141 gaaagccatt tccacaaaat ttttcttaat actcgaaact aaacagcttt ttcacaacct
     7201 ctccactaaa cggtattcaa aagcttacat ctgcggtaat aagtcccgcc aattcaaaaa
     7261 catgaacagc tgtttttgct tggctgttct aattacttga tgcagaacag ctttttcatc
     7321 acctcttatg gataaattcg gttcaacaaa cgtgggaatg gaatagcttc acgtacatgg
     7381 tcgataccag caatccaagt gactgttcgt tcaaggccta gaccaaaacc agagtgcgga
     7441 acagaaccgt atttacgtag atcaagatac catgaatatt ctttttcatc caaaccgtga
     7501 ttacggattt gttctagcaa gaaatcatag tctgttgccc gttcgcttcc gccaataatt
     7561 tcaccgtaac cttctggtgc gatcatatct gcacaaatta ccacgtcttc tcttgttgga
     7621 tgtggtttca tgtagaatgg cttgatggct tttggatagt ttaggataaa gacaggctgt
     7681 tcgaatgaat tcgcaatgaa cgtttcatga ggtgaaccaa agtcttcgcc ccattcgatg
     7741 tcatcaaatc catttttctt cagtaattcg attgcatcat cgtaagtaat acgagggaat
     7801 ggcaattttg tataagtttt taagacttct ttgtctcgtc ctagtacatc taatgcatat
     7861 tcgcaatgat ctaaaacatt ttgtactaag aatgctacat attgttcctg tacttctaaa
     7921 ctttcttctt gatgagtgaa agccatttct ggttcgatca tccagaattc gatcaaatga
     7981 cgtcgtgttt ttgatttttc agcacggaaa gtcggaccga atgaaaagac ttttccgaaa
     8041 gccatagcag cagcttccat gtataattgg ccactttgag ataaataagc tttttgatca
     8101 aagtaatttg tttcgaatag atccgtagtg ccttctggtg cagaaccagt caagatcggc
     8161 ggatcgattt tgacaaaatg atgttgatta aagaattcat acgttgcacg aatgatttca
     8221 tttctgatct gcataatcgc atgttgtctt gaagaacgca gccataaatg acgatgatcc
     8281 atcaagaaat ctgttccgtg ttcttttggt gtgatcggat aatcgtggct ctcgcttacc
     8341 acttccacat ttgtaattcc gatttcataa ccaaattttg aacgactgtc ttcacggatt
     8401 tctccagtta ctaacacgga tgtttcttgg tgtagatttt tagctgtttg gaaaacttct
     8461 tccgacactt cgctttttac aactacacct tggaaaaagg ctgttccgtc tcttaattgt
     8521 aaaaatgcga tttttccgct tgatcgctta tttgcgaccc aagcgccgat tgttactgtt
     8581 tctcccacat ggtttttcga atcgatgatt tgaatttgtt ccacgtatga ctctcctttt
     8641 atattccttg aatttcttca ggattaattt tgacttttac tctcaataaa ttgcttgatt
     8701 ctgcgtaccg cttcttctaa cgtagcgcga tcagtggcat aactcatgcg gacattttct
     8761 ggtgccccaa agccttcgcc agtcacaagc gctacccctg tttcttctaa aagatcttct
     8821 acccattgtg tgacattttc atacttacac atgcgtagcg tttcttttac attaggaaaa
     8881 agatagaaag ctccttgcgg cttttcaaga gaaacacccg gcagttctgc cacaagcgga
     8941 tataacgtat tcaggcgttc ttcaaaggcg ttccgcattt cttctactgt atcttgctca
     9001 cctttcaatg cttcaacagc tgcatattga ctgactgctg tcggattgct agttgattgg
     9061 gaagcaacag cgatcattcc attgatgatc acaggatttc ccaccgcata accaatgcgc
     9121 cagcctgtca tcgcatatgt tttagacacg ccgttgatga tgatggtctg atttttgatt
     9181 gcttctgaaa tcgttgcaat tggagtaaac tcattgccat tataaactaa acggccataa
     9241 atatcatcag caactatcaa aatatcattt tttactgccc attcaccgat tgcctgcagt
     9301 tcattcttgc tataaatcat tccagtcgga ttcgatggag aattgatgat tacggctttt
     9361 gttttttctg aacgtgcttg ttctagctgt tcaacagtaa ctttccagct attggattct
     9421 tcccctttca caaagacagg aagtccttct gccagtttta cttgctcacc gtaactgacc
     9481 cagtaaggca caggaatgat gacttcatct tgcgggtcaa ggatcgtttg gaaaagggta
     9541 tacaaagcaa atttcgctcc gtctgttacg actgtttgtg aaggttcata gacaagtcca
     9601 tagtttttct tcagataatc aacgattgcc tgtcgaagct ctgggattcc tgctgttggt
     9661 gtataatagc tagctttccc attgcggatt gcttcgattg ctgcttcttg gatgttttct
     9721 ggtgtcgcaa aatccggttc tcccacagtc aaactcagca catctctgcc ttttgctttt
     9781 aatgccttgg cctttgccgc agctgccaaa gtgacagacg gttctaatcg ttttgttctt
     9841 tttgataact ccatcccatt cattccttta ccttttaaat tcccttgatt gtcttgactt
     9901 catctccaga ttcaaagcca atcaggtaat aattcagttt cccatttgtt tcttttccta
     9961 ctacttccca cacaggctga tcatcataca tccctaaagc agctttttcg atttggattt
    10021 caggatgggc cgcagcaatt gtctgttttg cttcgttttc agtcagtccc tttgtttgat
    10081 ccaatacttt tactttttca ccagatttag gaatgataac ggcgatttct tttcctttat
    10141 catttgtacc tgtcagtgaa aagtatgtct tctttcgagt aaaccaataa aaatgatcgg
    10201 tttcctcaag atttgcatat ttctttgcga tttctactgc ttctttcttc gcctgcaccg
    10261 ccggacgact ggaacgcaag taaaaaatcg agctgatcac gatgaccgct aataaaaata
    10321 cgatcaagcc aagtaacacg cgattaatcg ttttttcctt tgtctgtttt ttcttcaagg
    10381 gtcgtcgctc ctttatcttc attccttttc attatagcag attttaatta tgaaaaaaga
    10441 cagctcctct aacttccttc ttcatttttc tttaagaatt catggatatc ctgatagatt
    10501 tcctccatag ctagctcttt gatcggtact tttttcggta atgcatggat gatccgtgcg
    10561 ccatattttg cagtgactag tcttcgatcc aaaataagca atacgccacg atctgtctcc
    10621 gtccttatca agcgacctaa tgcttggcgt aacttcaaag ctgctttagg tacggattcc
    10681 tggtaaaaag gattgatccc ctctgattct aaataagcgt tcctagcttt gaccatcggg
    10741 cgaagcggat tatcgaaggg taaacgtgtg actacaacga tctgcaaagc atctccaggc
    10801 aaatctacac cttcccaaaa gctgtcagcg ccaaacaata cgcttttttc tgacaaaatg
    10861 aagcgtttca aaagcttctc ccggcttcca ccaaaccctt gagctagtat ttctcgtcct
    10921 ttttctagca tagacagatg cattttctga tagaccttct gcaaaacatc atgagaagtg
    10981 aataacacaa gtattggccg atcttcttgt tcgatcagac ctgtaagtgc tgtctctaaa
    11041 taatcgatat atgcttgatt gctgacttga tggacggcag gtgcctcttt tggcacatag
    11101 atccttgcct gtttctcata atcataagga gaggcaatca ctttaagagg tgctgcttca
    11161 atgccaagcc tcttagagag atagtgtcga ttagggccga tcttcagcgt tcctccaata
    11221 taaagaatac gatcatatcg aggataccaa acagtcgacg gcaacatagc cgcttgaaaa
    11281 tcatggagat gaaaaatcat ctgctgcgct gtgttcccag gaacgaacca atggatcaaa
    11341 tgatctcgcc agtcttccag ccattgatcc atcagcaagt attgcttgtc taattgatca
    11401 aataggctat ataaacttgc taaatcgatc cgcatctggt ttgtccagct ttcttggata
    11461 atctcaaaag tcagacgcat ttgtgactgt agctgctgga tctcctgata aaaaagctgc
    11521 aggtgatcaa tggctgtccc agattccagt ggcagctgat ccaacatctc ttttgtcatc
    11581 atgacttctt ctggatactg tccgttaggt tgcttgccgc tcactaaact cattaatcct
    11641 tctgccatac aaatctgtgc ttcgcatagc gcagaaagtt cttctcgata aatcgataac
    11701 cagcgtaagg cttcatgttc tttcggtaaa tagctttgta ttcggtcaaa cagctgattt
    11761 ggttcttcta attgctggat ttgtttatgg aaatagttaa tacttaatcg tttgtcattt
    11821 actttttcag cgatttccgg caaatgatgt acttcatcga tcaacaaaaa tggactagct
    11881 ggaagcaatg gttcttttcg ctgtgtttct tgtactaaaa acgcatgatt gacaatcaaa
    11941 aaattacttt gcctgatttt cttttgcaag aaacgaacaa agtcttgttc gtaaaatgac
    12001 tgatttcttg ctaaaaatcc aatacctctg tgcgcgatat ctgcaaagaa tgaatggttc
    12061 aaatttgtta aatgtaattc atccaaatca ccagtcttcg tttgcgtcag ccaaactaag
    12121 accgccattt gatacaaagc atattgtttt tgttctggcg gttccacaag tgtgccttta
    12181 aaacgctgca aatcaatata gtggcgatag cttttgataa ttacaggttg tatgggctga
    12241 tctagcaatt gattcagcaa tggaatgtct ttttctatga tctgctgctg caaaactagc
    12301 gaaacggtac tgatgacagc gggtttttca ggtgtagcca aataactcaa tggcagcaga
    12361 taaccgattg ttttacccat tcctgtagct gcttcgatca tcaaatcttt tgattcatct
    12421 tttgtgaaat ggtcgtagac cgcattcatc agtctgttct gttcttttcg atacatcagt
    12481 gttttaccaa acattttttc ttttgcttgt ttttttcttg gatatgtccg ctcgccataa
    12541 tggacggatg tgaatagttc cacttctttt ttctgcaaag ctagcccatc gacgatttct
    12601 aatgagggat caagtggctc tggtttttct ttcatttctt caatcacatg ataaatgaaa
    12661 cgactcgtat ccatacctgt gtgtctactt aatcgcgcaa tctgctctaa cgtgatgatt
    12721 ggcaattttc tcatccgttc ttcgatcagc aaaagaagtt gacctgtcac ttcggcatca
    12781 ctatctgcct gatgaggatt ctcatgaata aatccaaggc tttctgacaa atcagctaag
    12841 cgaaagcttg gttccgtcgg caagaaaatt tgtgcaagtt ctactgtatc gatgcctggt
    12901 atcttcaaac taggaagtcc gcatcgcatg agttcatggt tcaaaaaatt ataatcaaaa
    12961 taaatattat gcgcgacaaa tatggtgtct gccaaaagat tgtaaatcgt ttgggcgaca
    13021 tcttcgaaat aaggcgcttt ttggacgcgt tgattcgtga tccctgttaa atgctggatt
    13081 tgttttgaaa tcttccgccc tggatgaata tcgatcgaaa aacgtgaagt gatccgacct
    13141 gattcaatca tgacgcagcc aaattggatg atccgatctt cttttggatt cgtcccagtc
    13201 gtttcgatat caacgactgc ataagttctt ggtttcaaaa tatcttcctc ttctcctgcc
    13261 tctaatgttc ttttgaaatt atactacaaa gtgcagaaaa atactctcat cgctttttaa
    13321 agaaaataga caaaaacgcc cagacacgca aatgtctggg cgtttatttt ttagtatagg
    13381 ttaattaagc tttagtaacg tttgttgctt gaggtccgcg ttggccttct tcaacatcga
    13441 aagttactgc ttggccttct tctaaagttt tgaatccgtc gccttggata gctgagaaat
    13501 gaacgaatac atcgtttccg ttttctgcag tgatgaatcc aaatcctttt tctgagttaa
    13561 accattttac tgtacctgtt tccataataa aaatcctcct tgtgtatcaa cacatatttt
    13621 gcaattactt gaatggtgta tatctggaag atgtttattt gaaacaagct accacagatt
    13681 accgaacaaa aactactcct atagtatatc ataccgttta caaaaaagct agagtttttc
    13741 gacttttttt attaaaaaaa gttttctcag cgattacata aagtgaaaaa ccgaactttt
    13801 ttttaaaata aacgacatat tgttcagttg gtgttttttt gctctgatgt tcttttttaa
    13861 actaaaaaaa ttattctttc tgactactta tcggttctgt ttcaacggtc gaggctgggg
    13921 aagattcttt agtaggtctg atgttctcat ggtatttctg atagcctatg acagttacca
    13981 gaagaacaag gcaaaccaat acgaccaacg agattagttt ttcttttttg ctcatatcta
    14041 tacctcataa ataacaggat gatgtccatc atatttctga gtatgagtaa aagcaaaagc
    14101 tgcagctgta gaatgtaaga aatgccagca actttcataa tcacaggtcg gacagtacca
    14161 aaagtaacca aatcttggct gcaaagaccg ttcttctgtt tcaggaatcg cagaatcaag
    14221 atctggtgtc tgtacataaa catttttgta cagacgtgtg cctgtaatag gaaaccgctg
    14281 tgtttcttca gcaaaaactg gctgacttgt taaacttagg gatagagaca gcaaacacca
    14341 taacagtctt tttttcataa agacctcctt atcgataagt ttttcccaat taaaatcata
    14401 tctcaagaac gcccgttatt cacattttgt tcataaatga tgttttttgt atcataatcg
    14461 tcaaaaagag gtcgtgacca cgtcacaacc tcttttttaa acggtgttcc agaagtagct
    14521 tcttcggaaa taagccgaaa tttcacaaaa atttgagaaa taatttttgt caatctcttc
    14581 ttatttcttg aagctgacca cttctgtcac aacctcttcc ttaaacggtg ttcaaaagct
    14641 tgcatctgcg gtaataagcc caccaaacaa aaaatatgaa gagctatttt tgcttgctgt
    14701 tcttattact tgatgcagaa cagctttttc acaacctctc atacacggtg tttaatcagc
    14761 tgaccttcgg tattagctca aaaaacggca aaatatgtga aactattttt ccgtttgttt
    14821 ctctaatact caggtcaaaa cactgatttc acaacctctt ttaataacga agaatcgctg
    14881 tcagactctt ttcatctggc gcatcttttt gatccaaaat aaacactttt ccgccattaa
    14941 tgatcacatc atctgctaat gcattcaaca cttgacgccg atcatattct gtttcaggat
    15001 cttcaccgaa accatcagct aagtttgacg tagcgataaa taaatgtgac acttttcctt
    15061 ctttcgcagc tggaacgata tcaactaact gatcgatgaa tttcttatct aagagtttat
    15121 tgtattcttt tgattcttga gctgcgagtt cacttgacag cttcttcgcc ccttcttcga
    15181 tatctctaaa ggatagctgc gcaggagaag cagaaatcgc aacgtctgca caataatagg
    15241 gatttttagc aatttttttg aacatcgtct gattttctgg tagagcaaat aaataaatcg
    15301 gccattgttc tggattttcg aaagaatcct tcaagtacgt atcaactgct tggtaatagt
    15361 tgacccaatc gatctctact tcttcatctt ttggatttac gccatggaaa gttactccat
    15421 ctcgggctcc gcctcctcca ttagaagaga agttcaaacc gccacctgtc agttcagatc
    15481 ccaatgcagt aacgacatca accggtgccc cttctggtag agatacttct tttacttgtt
    15541 tgttgctgac ttcatacaat ttcatggagt cgcggttcaa tcccaataaa taataagaat
    15601 agttgaactg cccatttttg ataatagcca gtaaataagg aagatcactt acatagtatt
    15661 gatcgtctac cgggatactc aaacgatgga tataggtttg gtcagcagtt ataatgaccg
    15721 ctacactcgt agttgcacta cgccaaaacg aaggatctcc taacaaattt tcaatttttt
    15781 cttggaacgg ggaccagtca tgttcggaat attttttctc aaaacgtttc tttgcttctt
    15841 tcgcaaaatt tttgaatttg atctgatctt tttccacatc ttgatgggcg acatgcgtat
    15901 tcagcatgat cgtgacgaat ggtcctttag cgccttctga agtcaattgt gacaataatt
    15961 ctttatcctt ttttgccata aacgtacccc tcctaaaaaa atcattcctt tgtttctatc
    16021 taaagtctac cacaacacta tttttccata caataaaacg tatctaaaaa aataaaacgg
    16081 tttctacggt tttaaattta gctatttttt taagttatct tcataatttc ctcaattatt
    16141 tagccccagt cttcaactat tcttcatgaa atgctgataa actaagaaaa agaataaaag
    16201 aggtggatct tatgcatttg attatgattt tcagtttatt aagtattatc agtttatttg
    16261 ctttcagcgc ttcccgctta ttagatgcgg aaacacagcc tattcctgta aaagtacgta
    16321 aaaacgaccg ctaaccttcc ataacgtgcg ttcttatcct aaagtttttt cagaaacatt
    16381 gaaactctct cccctctctg ataaaatttt aatttgtagc gaaacaaatt aattacaagg
    16441 agatcggata tgtccataaa aaaaacacgt ctagtcctat tattggctag tctcattctt
    16501 tgccttgctt cttttctacc agctgttgct gtgcaagctg aagatacttt caaagtaaat
    16561 gcaaaagcag cctttgctgt agatgcgcaa agcggtaaga ttctttatga tcaagatgga
    16621 gaaaaaacca tggggatcgc ttcaatcaca aaaatcatcg gtctttacat cgtccttgat
    16681 caagtaaaag aagggaaact atcatgggat gataaagttt caatttcaga ttatgcagaa
    16741 aatttgagtg tcaccccaga tttatcaaat gttcctttgc ataaagaaaa cacctacacc
    16801 gttaaagaat tattcgactc tgcaatcatc cagtcagcca acgcttcaat ggttgccttg
    16861 gcagaaaaaa tctctggcag cgaagcaaaa ttcactgaac gaatgaaaga acaattgaaa
    16921 gattggggta tcaaagatgc aacgatcgtt aatgcatcag gactgaataa ctcttatctt
    16981 ggcgaaaacc gaccagaagg tactggagaa aacgacgaaa atcaaatgtc tgctcaagat
    17041 gtggctatcg ttgcccgtca tttgatcttg gattttccag aaatactgga tgtatctagc
    17101 actacgacac aaatgtttgg cgaaaacacg caatcaccag tagaaatggt caactggaac
    17161 tggatgctcc caggattcgt gaattataaa gaaggcgtgg acggattaaa aactggtacg
    17221 actgaacttg caggagcctg tttcgtcggt acgatcacta aaaacgatca acgaatcatc
    17281 actgtcgtat tgaatgcaga cggccatgcg gaaaacccaa gtgcccgttt caatgaaaca
    17341 gctcgcttaa tggattattg ctacgacaat tggtcagaaa aagagcttgg aaaagccaat
    17401 gcaagtatcc ctagtctaaa aaccattgat gtaaaagacg gaaaagaatc aacagtgccc
    17461 gttgtgctta aaagtcctgt aaaagtatgg gtacggaacg atatggatac tggaaaatta
    17521 acaatcacac caactcttga caaaaaacaa gtcactgaca atgagatcca agcacctatg
    17581 gataaaggaa caaaaatcgg taccgcaacg atcaccttgg cagaagataa attaggttat
    17641 cttgaagaca acaacgcgcc atccacagaa atcatcacgg ataaaaccgt agaaaaagca
    17701 aatattttcg ttattggctg gcgacgcgtc gcagaatttt tcggtaactt gttttaattg
    17761 aacaaaaaga aaaaagcatc tttccatgtg gaagatgttt ttttgctttt tctagtttaa
    17821 ataacagctt ttttcatcta ttttcgttat actgtataag aaaaaggagt tgaatttatg
    17881 aatctaacca gagatctgat ttttttggtt ctctatctta ttggggtatt ctccatcgtt
    17941 tattggcgaa aacagaaaaa ggatccttcc ttgttctttt acagcagtac atggacgttt
    18001 gcggtaatct tgacttattt tgtcgtgttg gaaatttttt attcgacctt ttattttttg
    18061 attcccttag tgtttttcag tatctttgcc ttttcctatt tttcagaaaa gcgaaggctg
    18121 ttgaatggtc ttttattcaa tattttcctc attagttttg gtatctactt gtttgtcttg
    18181 ctatacgaaa cacaaaatat ttttcttggc ggactgattg ccttgatcac gatcccgtta
    18241 ctgcttgtct ttctattcgg catttatgga ttgatcgttt ttcttttttg gaacggtgtc
    18301 acagttttac gtagagagtc gcattcatta gctaatcttt taacgttgat actagccatt
    18361 tttcttacat tgtttcttgt ttttgacttt ttcttgttaa aatatttacc acaatggata
    18421 aatgctttgt ttttctgcat cccattgatc ttgatctatc tatttatcgt attctacaac
    18481 tttttgactg tctcattctt gtatcagttc aaccgccctc gatacaacca agacttcatc
    18541 gttgtgttag gcgccgggtt gatcaatgga gaaacagttt ctcctcttct tgccaagcga
    18601 atcaataagg cgattgcttt ttattgggca caaagccgtg cgacattaaa tccgcctatc
    18661 ctattaatgt cgggtggaca gggagcagac gaaaaagtac cagaagcaat ggcgatgaaa
    18721 caatatgcca tggaacaagg aattcctgaa agagatattc ttgtcgaaac caattcgaca
    18781 accactttgg agaatatgcg ctattcaaag gaaatcatgg atcagcaaat gaaaggtccc
    18841 tatcgcgcga tcttcagttc caacaattac cacattttca gagctggtct ctatgcacga
    18901 caagcgaaac tgaaggcaaa tggcattggg gcaaaaacag ctttctatta cttgcctaac
    18961 gcgtttttaa gagaatacat cgccatcttg atgatgaaca aaaaaagaca tatgatcatt
    19021 tgcggattgc ttttcgcagg ttccgcattc ttatcactga tcactttact tttctaaaaa
    19081 aacaaggtgt gacaaaacat atgtcacacc ttgttttttt ctttcattct cttaactatt
    19141 ggcaaaaaga gtatcccttt tctgaccgct acttgctgag cagaataaat accgctgttg
    19201 cctgaacaca taaagctgat caagcagatc ataaagaagt atactgccgc ttgtgaaccg
    19261 aacaattcga tccccatcac aaagcaggca atcggtgtat ttgtcgcacc agaaaatact
    19321 ccgataaagc ccaatcctgc aagaaaagga acagaaacat ggagcaaagg cgctagtgct
    19381 gcaccaagcg ttgcaccaat ttcaaacaat ggtgtcactt ctcccccttg atatcccgcg
    19441 cctaaagaca aaactgtgaa gaataacttc ccaataaaat catagacatg tgcctgtcca
    19501 ttaaatgatt cctgcagtaa tggaagactc aatccgagat aacgttgtgt ttgcaaaatc
    19561 aatgctgcgg ctacaactac agccccacct atcgtatttc gccaaacagg atgaggaatc
    19621 cattgtgcat atcgcgcttt taaaaagacg atcgaacggc tgaataccca accaatcaaa
    19681 ccaaaagcaa tcccagcaac aaaaactttg aagaacagca acatactcca ttcaggaatc
    19741 acacccattt ggtaatgtag atgagaaaca ccatagcttt ctgtcataaa atttgcaaac
    19801 agtgcagcaa agaagctagg gaagatcgct tctgttcgga ctttcccgat tgccaacact
    19861 tctaatccaa ataatgttcc agctaaaggt gtgccaaata cagaactaaa acccgcactg
    19921 attccactga taatcaagat ttcccgttct gatttatcca atcggaacaa acgtgctgta
    19981 ttatctgcta acgctccccc catttggact gctgttcctt cacggccaac agatcctcca
    20041 aataaatggg tagttatggt tccaaacagt gtaagtggaa taagtcgcaa cgggattttt
    20101 tcttctccac catttccttg atcgatcact aagttgtttc cacgactaga aagaccgccg
    20161 tgatacgcat agagataagc aaaaagcgca ccactaactg gtagtagata aaggagccaa
    20221 ggatgtgata gtcggatatc tgtcacaact gtcaggctat ttaagaaaaa agcagataag
    20281 ctccccatga atataccgag aatcgctgtg atcaccagcc acttcagcat gtacactaaa
    20341 atgcgtactg gactcggtaa ttgtttttcc ataaaaaatt cctcctcaat aaaaa
//
LOCUS       DADGKS010000051        20052 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.051, whole genome shotgun sequence.
ACCESSION   DADGKS010000051 DADGKS010000000
VERSION     DADGKS010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20052
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.051"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..392)
                     /gene="prs"
                     /locus_tag="JXV47_001957"
     CDS             complement(<1..392)
                     /gene="prs"
                     /locus_tag="JXV47_001957"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAX1487981.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRML"
     gene            complement(486..1859)
                     /gene="glmU"
                     /locus_tag="JXV47_001958"
     CDS             complement(486..1859)
                     /gene="glmU"
                     /locus_tag="JXV47_001958"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HAX1487982.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(2362..3180)
                     /gene="purR"
                     /locus_tag="JXV47_001959"
     CDS             complement(2362..3180)
                     /gene="purR"
                     /locus_tag="JXV47_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HAX1487983.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(3347..4171)
                     /locus_tag="JXV47_001960"
     CDS             complement(3347..4171)
                     /locus_tag="JXV47_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAX1487984.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(4144..4824)
                     /locus_tag="JXV47_001961"
     CDS             complement(4144..4824)
                     /locus_tag="JXV47_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAX1487985.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(4847..5785)
                     /locus_tag="JXV47_001962"
     CDS             complement(4847..5785)
                     /locus_tag="JXV47_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HAX1487986.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(6030..6881)
                     /locus_tag="JXV47_001963"
     CDS             complement(6030..6881)
                     /locus_tag="JXV47_001963"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HAX1487987.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(7035..9608)
                     /gene="mprF"
                     /locus_tag="JXV47_001964"
     CDS             complement(7035..9608)
                     /gene="mprF"
                     /locus_tag="JXV47_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAX1487988.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            9749..10555
                     /gene="proC"
                     /locus_tag="JXV47_001965"
     CDS             9749..10555
                     /gene="proC"
                     /locus_tag="JXV47_001965"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HAX1487989.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(10634..12190)
                     /gene="rny"
                     /locus_tag="JXV47_001966"
     CDS             complement(10634..12190)
                     /gene="rny"
                     /locus_tag="JXV47_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HAX1487990.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(12601..13650)
                     /gene="recA"
                     /locus_tag="JXV47_001967"
     CDS             complement(12601..13650)
                     /gene="recA"
                     /locus_tag="JXV47_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HAX1487991.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(13759..15000)
                     /locus_tag="JXV47_001968"
     CDS             complement(13759..15000)
                     /locus_tag="JXV47_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HAX1487992.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(15240..15818)
                     /gene="pgsA"
                     /locus_tag="JXV47_001969"
     CDS             complement(15240..15818)
                     /gene="pgsA"
                     /locus_tag="JXV47_001969"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HAX1487993.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(16027..16911)
                     /locus_tag="JXV47_001970"
     CDS             complement(16027..16911)
                     /locus_tag="JXV47_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1487994.1"
                     /translation="MAFETIGEKLRQARLNKKISLDELQQITKIQKRYLEAIDNDDFD
                     QLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQPETVSTSRKAMHQ
                     EESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDTASSLKVEGSVEES
                     SSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITDATKPVTLEFTAVN
                     RVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNATIKANGESVPVNP
                     GENNQSPKNVNLTLQYAE"
     gene            complement(17689..18975)
                     /locus_tag="JXV47_001971"
     CDS             complement(17689..18975)
                     /locus_tag="JXV47_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAX1487995.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(18968..>20052)
                     /locus_tag="JXV47_001972"
     CDS             complement(18968..>20052)
                     /locus_tag="JXV47_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAX1487996.1"
                     /translation="QLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNLFSQA
                     VDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYFENSP
                     EQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQLPFES
                     RETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFNGLFG
                     GFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQLESLR
                     NGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRMESVT
                     IKEIQQVAEQIELQAIFFLAGGNANE"
BASE COUNT         5662 a         4401 c         3493 g         6496 t
ORIGIN      
        1 agcattcttg ttgcaccagc tttttgaatc atgtttgcta ctaatttcgc tgtgattggt
       61 tcccgtgcac gtgctttacg gtcttgacgc gcatagccat aataaggcat gactacgttg
      121 attgtttttg cacttgctcg tttcagtgcg tcaatcatga tcagcaactc catcaagtta
      181 tcattgactg ggctgctcgt tgattgaata acatagacat gcgatccacg aatactttct
      241 tcaatgttta cttgaatttc tccatcacta aattgagtaa cagatgattt tcctaactcg
      301 acgccgactg ctgctgcaat tttctctgct aatgggcgat tggaatttaa cgcaaaaatt
      361 tttaatcttg ggtcaaagta atgttttgac atggggacct ccactttctt tttcacaact
      421 ctagaattct acctaataaa tagtagtcat attttttaaa taaatcaagt gattttgcaa
      481 aagtcttagt ttagataagg gagttttttt gcatatcctt ctttattgac ttgtcttgct
      541 ctcgcaattg ccagcgcata ttctggaata ttgtctgtaa ttgttgaccc ggcagcaatc
      601 gaactgtttt tagctacctc gacaggtccg atgatattcg tgctagaacc aataaagctg
      661 tggtcgccga cagtcgtatg atgtttgttc tttccatcat agttgacgaa gacaacacca
      721 catccgacat tgatttcttc tcccagcgta gcatcaccaa cataagtcaa gtgaccgact
      781 ttagttcctt tgccgatttg agcatttttc acttccacaa agtttccgat atggacgttt
      841 tcgccaattt cagcttttgg tcgtaaatgt gcataaggtc ccacatctgc atgtttcttg
      901 acatggctgc tttcaatgac tgagttttca atgacgacgt gatcctcaat cctactgtct
      961 acgatttttg aatgtgaccc gatgacacaa tcagaaccaa tgactgtatt tccttggatt
     1021 tgtacacctg cttcgatcaa tgtgtctgga ccgatttcta cgcctgcatc gatgtatgtc
     1081 gttgctgaat cgacaaagct tacgccattg accatatgca tctggttaat tcgctttctc
     1141 atgatctcat ttgctttagc taacgcgatc cgatcattga ctcccattga ttcttcaaaa
     1201 tcatccgttt gataagcagc aactgtatgg ccttcttctt ttaagatttc gatgatatct
     1261 gttagatagt attcaccttg agcattgttt gttccaactt tgcttaacgc atcgaacaaa
     1321 gcttcgttgt caaaacagta agttcctgta ttgatttctt gtacaagagc ttcttctggt
     1381 gttgcatctt tttgttccac gattttttct acgatcccaa tatggtcacg gatgattcgt
     1441 ccatatcctg ttgggttttc tgcttgtgcc gtcaagatcg ttgcacttgc attttttcct
     1501 tggtgatatt caaaaagatt gttcagcgtt tcagtagtca ataatggtgt atcgccactg
     1561 ataactaacg ttgttccttt ttttccttcc aagaaagaag cagcttgcaa aacagcatgt
     1621 cctgttccca attgttctgc ttgtaacgca tatttactgc gttctcctag ttgtgcttta
     1681 acttgttctg ctccgtgtcc aacgatcgta atcacttcat ctggtttcgt ttcactgacc
     1741 cgattaatga tatgttctac cataggttta ccagaaacgg gatgtaaaac tttatataat
     1801 tttgacttca tgcgggtacc tttccctgcc gccaaaataa ttgcataacg tgcgtccaac
     1861 tgcgtcactc ctaaatatag tttgctgatt tcagtttatc ccagtatacc cattttttca
     1921 acaaaacaag tgattttctt ttatcccagc gttttctgga taaaaaaata gatagaccat
     1981 aacgggccta tctatttggt aaccggtgct ctcctgccaa ctcctcggtc acaagtcaca
     2041 ctactcataa aacatgaaaa gctgtttttt gaaatcgttt cttgtgactt agagttaaac
     2101 ggtaggctta caacctcttc attaaacgtt tttcaatcag ctgaccttcg gtattagctc
     2161 aataaacggc aaaatatgag gagcaatttt tccgtttatt gagctaatac tcaggacagg
     2221 acgctgattt cacaacctct agataaacgg tgttcaaaag ccagtttctc ggtattaagc
     2281 caaatttatg aaaaaatgtg gaaagccatt ttcacaaaat ttttcttact actcgaaact
     2341 aagcggcttt ttcacaacct cttattctga aaaataattt cctggcacaa ccgtaatatt
     2401 tttcgtttga gtatctacat ctttgacata aagcagtgac gtataatcat cgatggcgcg
     2461 atgaccgttg aattttgatt cggcaaatac agtgatgcca acaagttctg attcgaattc
     2521 ttcaatcaag ctcttcattc cgttgactgt tccgccgcct ttcatgaaat catccactac
     2581 aaggacacgt gaaccacgtt tcaaacttct cttagacagt tccatctttt caattctttc
     2641 agaagatcca gacacatagt tgacacttac tgttgatcct tctgttattt ttgagtcccg
     2701 gcgtacaata acgaatggcg cattcagata ataggacaca gcttgggcaa taggtacgcc
     2761 ttttgtggct acagtcatta cagcatcgat tttttcacca aggtatttag aagcaatgat
     2821 tcttccaact tgacgcagca gttcaggttc tcctaacaaa tcagagagat aaacatatcc
     2881 tcctggaagc agacggtctt gttctgatag acgttctgct agagattcaa tatatttttt
     2941 cgcctcttca tatgaaattt cagggatgaa caatacacca cctgcagcac ccgggattgt
     3001 ttccaaggtt ccataccctc gttctttaaa tgttttcttg atgattccca aatcttcact
     3061 gatagaagat ttagcagatt cataacgttc ggcaaagctt gttaaggaaa tcaattcatg
     3121 cgggtgattc aataaatact gtgtcatgtc aactagacgt tcactgcgac gtactttcac
     3181 ctattccaac tccttttaag aaattttatc gttttacatt atataagttt ttcttcaaaa
     3241 attcgagcat tttatgaaaa aataagaaaa tagttcggta tttattaaaa taaaaagaag
     3301 cctataaaaa atttttcgtt tttataaggc ttcttttctt tataatttag ttattttttc
     3361 ttctgaaggc aaccaatatt cgtttgatga tatttacaat caggaacaaa gcaataaaga
     3421 ctaatgtgat tgttgctcct ggaggtgtat ctagataaaa cgagctagtt agtcctgaca
     3481 gcatccctag aaatcctaca caaacactga tagcaatcac gacattgaag cttttgccta
     3541 atcgcatacc gattgctgcg ggaagaacca tgattgcgga tatcaaaagt gcaccggcaa
     3601 tcgggatcat cacagcaata gccacaccag taatcacatt gaacatcatc gacatcaaat
     3661 gaacgggtag cccatccacg tgggcggtat cttcatcaaa agtcagaaca tacatcggcc
     3721 gtttgaataa aaagaacaat ataccgatgg caacgaataa gattcctaaa aagatgactt
     3781 gctcccatgt aatggtcacg atcgaaccaa acagatagga ttggatactt gttgctgaat
     3841 tccctccgct caaattcatc aatactaacg ctagcgccaa accaccagcc attaaaatgg
     3901 caatggagat ttctgaatag gttcggtaga tcgttcgcag atactccaat atcacagctg
     3961 ctaatacaac gactagcatg gtcgtaagtg taggattaag gttcaaaaag aatcctaacg
     4021 ctacccctgc taaagagaca tgagaaagcg tatcagccat cagcgattgt cttctgatca
     4081 ctaaaaacac acctagcatc ggggcgattc cggcaatgaa gatagcggca agaaacgctc
     4141 ttctcatgaa ttcatatgaa agcaacgcca ttgagaatcc tcctttctca ccagtcggat
     4201 ctgtctgtcc gcatactgtt tgatatcttc atgatcatgg gtgatcatta gaactgattt
     4261 cccatggaca tgcgcactat gtcggagaag acgataaaat tcatttctgg attcttcatc
     4321 catacctgtt gttggttcat caagaacaaa taagtcaggg tcagtagcaa aaatacgcgc
     4381 taaactgatt cgctgctttt gtccgccaga caattcacct attcgccgat ttcgcatatc
     4441 ccacatccct acagcttcta aagcacgctg tacatgttga tgatcttttt cagagagacg
     4501 cttgaaccag cggcctcttg gatatcttcc tgaacggact aattcgatca ccgtactagg
     4561 aaaacctgca ttgaaagatg caacttgttg aggaatataa ccgatactta atttttttcc
     4621 ttcttgattt ttctcagcaa tctttatcat tccttttgaa ggtttcagta atcctaacga
     4681 tgctttcacc aaggttgact tggctgctcc attttctcca gttaaaatga caaattcacc
     4741 cgcatctaca tgataagaga catcttctag tacaggttca tcatcatagt aaaaggtcaa
     4801 atcagatatt tcgatataac gcaccttaca acctccattc taaaacttaa ttgatacttt
     4861 cttttaaagc tttcagattt ttttccatga cagaaatata attttcgcct gctttgattt
     4921 gttcattagt caagctttct aaaggattca acacttctag cttcactcct gtttcattcg
     4981 acaatgtctc agctaccttc gaagaggcat tttcttcaaa ataaatcact ttgatgttgt
     5041 ttttcttcac aaattctttt agctcagcta agcgacttgg tgtgggttcc tgatctggtg
     5101 aaacgcccga aatcgctact tgttttaagt cgtattgatt cgctaaataa gcaaaagcag
     5161 catgctgagt gacaaatgtg cggtttgttg catcttttag ctcatcggag tatttttgat
     5221 ccagtgcttc aagctttttg atataagcat cggcattctt cgtaaaagtt tcctttttat
     5281 ctggatattt ttcgcctaat tcttcagcaa tcgttctgac ttcttttata gctaataccg
     5341 gatcgagcca aacatgtgga tcgtattcat gtgaatgacc atgcccttct tctgattctt
     5401 catgttcgtc tgcttcttgc gattctaaac ggtcgattcc tttagctgct tcgatcatca
     5461 aggtctgttt gctatccact gaatccttta acgaatccac aaaaaattcc atgtctgaac
     5521 tattatacac gaaaacatct gcatcggaaa tttctgctct ttcttttgca cttggttcga
     5581 aatcatgcgg ctccgttcca gcagggatca aaagtttcac gtttccttca tcccctacga
     5641 tctcttttgt aaaatcatac atcggataaa aagtcgtaac gatcgtcaaa tcctcttttt
     5701 tgtctgcttc cttgttcgta tttccacatg ctgcaaacag taaagcacct atcattaccg
     5761 tagctgtcaa aagatatttt ttcatttata tgctcctttc aatgaacaaa tcggaatttt
     5821 acgatttatt aacgtgaact aatgtatcaa aataaaaaaa cacagtcaat agaaatccat
     5881 caatttctga tttaagcatg tatattcttg attaaatcgt aaaatggatg agttgctgct
     5941 catatctagc catttcacta caataaaaaa ctgaagaata ccattttagg attcctcagt
     6001 ttttcatcac ctattttact tcttatattt tattgcaggg ttcgtactaa ataaacttcc
     6061 tcacaaaaac cttttaaccc attatatact ctctgcgctc ttgaataatg ttgacacaag
     6121 gcaaaaacgg ttggtccgct tccactcatc aatgcagcat ctgctccgta cttgatcata
     6181 cgctctttga tttgatggat gactggatgc cgctttcccg ttatatcttc taaactgttt
     6241 cccatttttt tgatcatctg ctgataatct tgctctcgga tggcttcagc aagtccgtgg
     6301 atgtcttgat gttggatggc ttgcgtatct acttctctaa acactgtacg tgtagagaca
     6361 ctcattcttg gtttgaccaa cacaacccag cactgtggca tagaaggtaa tacttggatt
     6421 tcttcccctt tgccaccgac aaatgccgta cttccgtaga cacagtaagg aacatctgta
     6481 ccgacttcca aaccgatttc tgccagttct tctaacgaac agcccagatt ccataattgg
     6541 ttgatccctc ttagagcagc tgcacagtct gtacttcctc cgcctaatcc agctgctact
     6601 ggaatattct tcttaacaaa gatcttgaca ccggttttga tattgtattt attttttagc
     6661 aataaagcag cttgataaac attgttccgt tcatctaccg gtaaaaatgc tttatttgtt
     6721 tctacaatga ttttgtcttc tgttatttct tcaaaaaata gatgatctgc caagtctacg
     6781 ctcgacatca ccatttccaa ctcatgatac ccatcttgcc gtctatataa tacatccagt
     6841 cctaaattta tcttggctgg cgctttttca atcaattcca tcctctcacc cattcgaaaa
     6901 gtctaagtcg caagtattct atcataggga aaaataaaag tatagcttat gtctgcctag
     6961 tggttgattt tgtcatcgtt tcaacagctt tcacagaatt ttctcttcat aatccaaaca
     7021 agttctagtg attcttataa ttctgtgagc acttcttctg ccaaactcgg aacatttcct
     7081 ttttcttttc ctatcagact gagtagctgc atggtagcaa atccgaaatt acttcctttc
     7141 ctataagcaa aataacgtcc ttcccaatga tcgacatatt ttaatttctt ttcataagca
     7201 gactggaagg aatagaaaaa attaccataa ttatatacga tatgcatgac tttttcttga
     7261 aagaaagaaa aatctgtttc tccaacatta gctaatggag ctaagcctag attggcttcc
     7321 gagtagccca ttttctcgta tacaataaac agattggcta acagatagtc agctaattcc
     7381 tcagattctt taggtaagac ccgcaacaaa tcatatcccg cctgcttctt cgtcatcggc
     7441 tgagcggtga tgaagccaac gactttttga tctttacgga caataccgac accgctagat
     7501 aatacatatg atttatcaaa tcgtcccaca gagaagtatt tttctcgtgc accttgaagc
     7561 catttttgtg aaacttcatt tacagcttga tgtaattctt ccggcagttg atcgtaccaa
     7621 gtaaaatggt atccttcttt catcaaacgt tgatattcaa gttgctgact cagccgagac
     7681 aagtcttctg ttgctagatc aacaatccct gcttcaccta ctttcgtgaa gtgaaaaccc
     7741 aattcatgaa gcatcactac gtagctttct gatatcttat aaaacgcaag ctgatagcct
     7801 aaacaatctg cttgtttcat aaactgattc gttgctgccc gcatcatttt aggattgcca
     7861 actggatctc ctaaaacaaa gcatttgttt cctttgatct gataaccaaa aacgacttga
     7921 tcttggtcgt cttcttggta ataaaaataa ctgtaacctg acaagcgaag ctgatggctt
     7981 gtagctgtgc ctccgtatgt ttccaataaa cggtcaaaac ggtctttttc gtactcactg
     8041 ccaagcttcg tagtatcttc agctaaatat tgataaagcg ccactaaagc tagcaatgag
     8101 atgcccaaac caataagccc tgagaaccac acatcatctg aaggaaacaa aataaaatga
     8161 tttcctgtta ttcgaccgac taaaaagcgt ccgctgtgat agcctgcaat tgcgtaaacg
     8221 ataaacaaaa agccgaacaa gctagcatca aagattatag ctccccaaga ataaacgaat
     8281 tttgttcgat aaaattcttt tctggataac cacacagcta acagaatcaa gacatatacc
     8341 aatatcaact gccaagataa cgtacgtgtg attgtattta aaataccaaa agatagtaaa
     8401 gcaatcgtag gcagaaatgc ctttttgact tttactgaaa gtgctctagc aaggccgagt
     8461 aataaaaagc caaccaatag attcactgtc tgatctaaaa aattgaatga gaacggcaat
     8521 aatacttgaa atagccgact gattgcagac agattagtga ttgttgatag aagtaccatc
     8581 atgatccccg caaaatagac agcacttacg agcacgatat gcgcaacctt ttggaaaaac
     8641 agtcgcggaa tgttatctaa aaatcgattg attttgactc ctgtatgtgt gatgaacaat
     8701 agaagtcccg tcataaaagg tagaacataa taaaacaacc gataatataa tagccaaact
     8761 actgctacat cttgccgaac agacaattga ctcattccta agatcatcaa aacgtcaaaa
     8821 gtccccattc cacctgggac catcgtcagc attcctatca atgtagcaat catgaacata
     8881 ggatagatcg aaagcatcga aatatctatt ctcatcaact tgccgatgat caaaaatacc
     8941 gcaagggctc ccgtccattg tccaaaggat gccagtagca gaccaagcaa gccttttgga
     9001 taaaactcga agaacaatgt ctttctcttt agataagcaa aaaagaaaat gactggtgct
     9061 aaaaaactac cgccgaaaag ccagatccaa tagcttcgaa aaatactttc tgactgaata
     9121 aaaaagacat caataaatgt aagaaacgac catacagaca aaccagtcag cataaatagt
     9181 gcgacttttg atacagtggc taaaaccatt tttctatttg tctgctttcc ataaaaacta
     9241 gcccgcagac ttgctcctac cacaccacca aaaccggcga gattgttgat cgtgtttgtt
     9301 acccacgcag caagaagaaa ctcttttctt tccatttttg gttttccttg tttttctaag
     9361 actctgatcg tcacccaatc atacaacaac atcggagtga cacccagcag tccagccaga
     9421 atcatgagca ggatcgtcat gcggctttgt tgtcccatcc tttgccaaat atcttgccaa
     9481 ctcatgccat tagcaatatt tgcgacttga tttgccacaa agactaacac ggagccgaaa
     9541 aaaatcagtt ttaaaatcag actatgttcc tttatccatt gcagcatcaa gtatcgttta
     9601 tttttcacat tttcccattc ctaacttgta tacttttgtg tcatacccca atgttatctt
     9661 atttatttta atttttccac tttagacctg ttctttgctt gcgatgatag aaaaagaaag
     9721 atatcctaat gctaaaggag aggataacat gaaagtagga tttatcggca cagggaatat
     9781 ggcacaagct attattgatg gtttattaaa aaaaggaaca gtctcgaaag aagaggtgtt
     9841 cgtttccagt ggacattttg aaaatgcaca aaaatttgct gctgaaactg gcgtccatgc
     9901 atgcaaaagt aatcaggaag ttgcatcaca atcagatatc gttcttttag ccgtgaaacc
     9961 aaaaatcatt gaaaaagtat tggaagaact aagagaatat agccagaaag tcttattcat
    10021 ttctattgct tcaggaaaat cattaataga tttagaaaca gcgcttgaag atcctcaggc
    10081 ctccatcgta cgtgtgatgc cgaatgtcaa tgtcagcgta ggagcaggcg tttctgcgat
    10141 ttgcaaaaat gaagctgcca cggaggaaca gcttcagcaa gctacgatga tttttgaagc
    10201 aatcggcagc gtctatcctt tagcagaatc agatttcagt acattcattg gccttgctgg
    10261 cagctcaccc gcattcgttt acatgctgat cgatgcgatg ggacggactg gtgtactgaa
    10321 tggtttgtcc aaacagacag ccactgagat tgctgcaaaa gcaattatgg gttcttgtca
    10381 aaaattcctt tcaagtgata aaaatccatg ggaacttgta gaccaagttt cttctcctgg
    10441 cggtacaact gttgcaggtg tagttgcctt agaagaagca ggattcatcc cagcaatcat
    10501 caaaggaatc aatacgacga tcgagaaaga tcttgagatg ttgaataaaa aataatgata
    10561 gcaatgtttt ttcgtgcctt acaaaaaaag aagagctgtg gcttttgccg cggctcttct
    10621 tttgtatttt ttattattta gcataatcag ttgcacgagt ttcccgaata acgattactt
    10681 tgatgtgtcc aggataatcc agttcttctt cgattcgttt acgaatatca cgtactaaac
    10741 gaacagcgtc taaatccgag atttcttctg gcttgaccat tacccgaact tcgcgtccag
    10801 cttgaactgc gtaacttgat tctacaccgg cgaagctgtt cgaaatattt tccagacttc
    10861 ttaaacgacg gatgtagttt tctaatgatt cacttcgcgc accaggtctt gctgctgaga
    10921 gcgcatctgc tgcagctaca aggacagaga taacagaagt agcttccaca tctccatgat
    10981 gagaagcgat cgcgttgatt actactgggt tttctttgta cttggcagct aattccgcac
    11041 cgatctcaac gtgagatcct tcaatctcat ggtcaagtgc tttcccaata tcatggagca
    11101 acccggcacg ttttgctaat tggatatctt cgccaagctc tgctgctaag ataccagcta
    11161 attttgcaac ctcgaccgaa tgcttcaaga cgttttgtcc ataactagtt ctgaatcgca
    11221 gacgtccgat gatcttgatt agatctggat gaagtgtatg agcaccgact tcaaacgctg
    11281 cctcttcccc gtattcgcga atacgttcat ccatttcttt acgagatttc tcgaccattt
    11341 cttcgatacg cgctggatgg attcgtccat cttgtatcag tttttccaag gtcatccgtg
    11401 cgatttctct tcggattgga tcgaatccgg aaagaacaac tgcttccggt gtatcatcga
    11461 tgattaaatc gataccagtc agcgtctcaa gcgttcgaat attacgacct tctcgtccaa
    11521 tgatacgacc tttcatttca tcattcggaa gggtaacgac tgaaacagtc gtttctgaaa
    11581 cttgatctgc tgcgcagcgt tgaatcgcta atgataataa gtttttcgct ttgcgatctg
    11641 cttcttcttt ggcacgctgt tcagattctt ttaccattag agttaactca tgattcagct
    11701 cttcttcagt cgatttcatg atgacatctc gtgcgtcctc ttttgataaa ccagcaattt
    11761 tttctagttc tttttgttga tcttcaatca ttttttcaac gtctttttct cgctcttcaa
    11821 ttaattgctg ttttgaacta agtgcttctt ctttactttc aagtgagttc tcgcgttttt
    11881 ctaacgagtc atctttacga ttcagcgttt gttcgcgttg aatcaaacga ttctcttgag
    11941 attttaattc taacttactt tctctcagct cactttcaac ttcagaacgg tatttctgat
    12001 tttcttcctt agcttctaac aatgcttctt tttttagagt ttctgcttct ttttttgcac
    12061 tatcgatgat tccagcagct gatgattgtg caccagctat ttctttctcg tgacgtgact
    12121 ttgcgaccat aaaccctaaa ccaagaccga caattaaacc gatgatagcg aggagaatgt
    12181 tgaataccat aaaatccacc tccatactat ctttttcatt tttatcatct atacagcttc
    12241 tatgataaat tattctaaac tcgtcaatat gcatcttcgc atatatgtgt acaaaaaaca
    12301 tgcacaactt tattctaatg tttgtacccc gtagtgtcaa ctttaaataa acaaagaaac
    12361 ggctttctac ttattcatta aacgatggtt tttaaaataa atgacactag tttcatatag
    12421 gtaaaccttt aaattgagaa acttttctat taaattattc tttgtagatg aacagatatt
    12481 tttattttat gtacccactc gtataattaa ataactcacg atttctttat tcaataaaaa
    12541 aacggcaggt caaggagagt acctactctt cagaccagcc gtttttgttt atcataattt
    12601 ttattcttct actaaaggca attcttcttg tcctttttca tcttctggga cagcgacttc
    12661 ttcaccaata ccataagctg ctctaactag agcagaaact tctgccatca tttcaggatg
    12721 attagccata tagattttag cgttttcccg tccttgacca atccgatctt ctttataaga
    12781 ataccaagca ccgcttttat caacaatgtc tttttctact gccatgtcta gaagttctcc
    12841 ttcttgtgag atccctaaac catacatgac atctacttca gcgattttga aaggaggtgc
    12901 tactttgttt tttacgactt tgatctttgt acggttacca acaatatctg taccttgttt
    12961 caattgttct gcacgacgta cttccaaacg gatcgttgcg tagaatttca atgcgcgtcc
    13021 tccaggagtg atttctggat tcccaaacat cacgcctact ttttcacgga tttggttgat
    13081 gaaaatagcg attgtttttg ttttgttgat cgaaccagag agtttacgca atgcttgaga
    13141 catcaaacgt gcttgtaacc cgacatgtga gtcacccatt tcgccgtcga tttctgctcg
    13201 tggaactaaa gcagcaactg aatcgactac tacgatatct acagccccac ttgatactaa
    13261 agcatcagcg atctctagac cttgttctcc tgtgtcaggc tgtgaaagaa gtagttcatc
    13321 gatattcaca cctaattttt gtgcatattg cggatctaac gcatgctcag catcaatgaa
    13381 agcggccgtt ccgccatttt tttgtacttc tgcaatagcg tgtagtgcaa ctgttgtttt
    13441 acctgaactt tcaggtccat atacttcgat gatacgtcca cgggggtaac cgccgacacc
    13501 taaagcgaca tctaacgcaa gagagccact tggaattgta gagatttgtt ggtcgatttt
    13561 ttcgcccaat ttcataatag agcctttacc atagctcttt tcaatttttt tcagtgcagc
    13621 atctaaggct gctttacgat catctgccaa tacgataatc ctccttatat ttacaaatca
    13681 gagcaacatt tcattatcct tatcatatct tttttagtga aaaaaagcaa gaaaaaaccg
    13741 aacaaatatt cgcatttatc attttcttaa aagctgtttt ctcaaaagat caaatccttg
    13801 cataaccgca ttatatctga tagcagcacg atctctggca aagtgatatt tttccgaaac
    13861 cacgccgtct ttagatgaaa tagcgatcca tactgttcct gcagattgac cttctaacgt
    13921 gtccggtcca gccactccgg tgaaagctac actgtaatct gttcttgcta tctcacgtgc
    13981 ttgaatggcc atctgctcca cacattcttt gctgactgtt ccatattctg ctaatagctc
    14041 cggatcaatc tccagaaaac cagcttttgt ttggagcgag taggtaacga atccgcctgg
    14101 aaatacttca gatacaccag caatgtcgcc taatgcggct tggaaggcgc cggctgtcaa
    14161 actttccgct gctgttacag tctgcttgtt ttctttcagt agttccacta cgacttttgc
    14221 tagcgaatta tcatcgccgt atccataaaa atattcccct actcgttctt ggattttttc
    14281 ttctaatgct aaaagagctt gattccctgc ctgaacatca tttgttttca ctgtcagtcg
    14341 taatgtcact tcatttggtt tggcatatgg tgcgatcgtt ggattgatct gtgtctcaat
    14401 cagatctttt agctcagtga ccagtcgcga ttcaccaatc ccataaaagc gcaaaacttt
    14461 agaaattagt ttttcttcag aaggaaaacg ttcctctagt aaaggacgta cttgttccac
    14521 aaacattggt ttcaactcat taggcggacc gggaagaagg atatacgcat gtgtatctgt
    14581 ttgataaaaa gtccctaaag caagccctgt acgatttggt agaggaaccc cgccttcgat
    14641 aatctgggac tgttgcagat tgtttttggt catttttcga tgggttgttt caaaatatgc
    14701 caataatttt ttgtatcctt ccgtattttg tatgagagac ttaccgaggt gagccgcagt
    14761 tgcttctttt gtcaggtcat cttctgtcgg tcctaatccg ccacataaga gtatgagttc
    14821 acttcttgtt tcagctagag caatcaactc ttctaaacgc tgctgattat ctcctacaac
    14881 tgtttgataa taaacttcga tacctagatc agctagctgt tctgacaaga aagtggcatt
    14941 cgtattcacg acttgtccta gtaaaagttc tgttccgaca gctattattt ctgctttcat
    15001 tacttcccgc tcccttatat agtatacgct gtatttttat atttttttat ttaaaaagag
    15061 ggcaaggagc tgtgacaaaa atcttgtcac agctccttgt tccaaataaa cagtgttctc
    15121 ctgccaaaac ctcggtcata agtcacaata tacataaaac atgaaaagct gttttttgaa
    15181 attatccctt gtgactcaga gttagacggc aggctcacaa cctctccact aaacgatact
    15241 tacattgatc ctttgaacac accgctgttt ttgatgaagt aatccacacc tgaatagata
    15301 gtaaagatca gacaagcata aagcatgatt tgatctactg gaataccgat caggctgaat
    15361 gggatattat tgataaacag caagataata gcaaccattt gtgtagccgt cttgactttt
    15421 cccggccaag ctgcagccat gacttctcca tgttcgacaa gtagtaaacg caagcctgtg
    15481 acggctaatt cacgacagac aatgatcgct actacccaac caggggcctt tccttggtca
    15541 accaacatga taaaagcagt cataactagc attttatctg ccaacgggtc cgcaaacttg
    15601 ccaaaattag tgacaaggcc tcgcgcacgg gcaatttttc catctaacca gtctgtgata
    15661 ctagctaaag caaaaataac tgcacctact agctgtgtga cagccagtgt ggtgtctcct
    15721 acgttaaatt gtccccaatc taaaggtaaa cctacaacca aaatgaaaat cgggatcata
    15781 caaattctaa gtacagttaa tttatttggt aaattcacac tatcgactcc tttcttccct
    15841 attctacgtg actatcagcg aagtttccac cgatattatt tacttttcca aatgaattta
    15901 ttcaaaggag tatttttatt gaaattgatc tttttgaatt aacgaagaag gaccgcgaca
    15961 cagatttgtc acgatccttc ttttttatac ctacaagtaa acagatgcgt aaactaattt
    16021 atacgatcat tctgcgtatt gaagagtaag gttcacattt tttggactct gattgttttc
    16081 ccctggatta actggtacgg attctccatt cgctttgatc gttgcattgc ttgctgcacc
    16141 aatcgtgatg gtcgcatttg ttgctgtttc cggtaacacg gtactctgtg tttcatttgc
    16201 tgccagtgtc ccttgataaa cataggcatt gtctactagc acacctaacc atacacgatt
    16261 gacagcagta aattcaaggg ttacaggctt ggtagcgtct gtgatattta ctgcgatggc
    16321 actgccagaa tcttctcctg tagctattgc cattttcttt tcttcacttg attttgttgt
    16381 tgattctact gtagaagact ctttggtctg cgtgctttgc tctgaggaag aggactcctc
    16441 gactgatcct tctactttaa gcgaagaagc tgtgtctccg attattggat cagcttgacg
    16501 atcttgccaa gtcatatagc ccacgacaac gacaatcgcc aaagcaacca atcctaataa
    16561 aatgacagga agacttgtcc aaaagcgact tggatgcgat tcttcctgat gcattgcttt
    16621 tctagaagta cttactgttt caggctgcgg acgttcaggg accgatcctg tcaatttgct
    16681 tttcccatca aaaacatcga ctaaatggtc tccatcttct cctacagctt cagcgtattg
    16741 ccgaataaat gcccgcacgt aaaatttacc aggcaattgg tcaaaatcat cattgtcgat
    16801 tgcttccaaa taacgttttt gaatttttgt aatctgctgt aattcatcta aagatatttt
    16861 tttattcagg cgtgcttgcc gtaatttttc tccgatggtt tcaaaagcca ctcgttcatc
    16921 ttctccagtc tgtttgattc tccgaagcat ctgctgttgc aacgaaagac gttatgtttg
    16981 ggtgctgtga caaaagtcat gtcacagctc cttttttccg aataaacatt gttctcctgc
    17041 caactcctcg gtcacaagtc acaatatcca ataaatataa gaagctgttt tttgaacttg
    17101 ttccttgtga ctcggagtta aacggcaggc tcacgacctc tttcttaaac ggtgttcaat
    17161 cagctgttcc tcggtattag ctcaaaaacc ggcaaaatat aaggagatat ttttccgtat
    17221 gtttctctaa tactcaggtc aaaacgctga tttcacaacc tcttccttaa acggtgttca
    17281 aaagcttgca tctgcggtaa taagtccaac caagttaaaa acattaagaa gctgttttta
    17341 cttggctgtt cttattactt gatgcagggc agctttttca caacctcttg gtacacggtg
    17401 ttccagaagt agcttcttcg gcaataagcc gaaatatcac aaaaatttga gaagcaattt
    17461 tcgtaaattc cttcttattt cttgaagctg accacttctg tcacaacctc tttgattact
    17521 tcgtttgatt ttattttaat ataagttgat taaaagagag catgatttgt tttattttct
    17581 cactaatttt tccaacacaa ctaagaatac cataaaagct gattttggag gaggttccta
    17641 ctacaagtct aaaacgaaat ttaagacttt tcctcataaa atactggttt attttggtct
    17701 catgtaaaac tcgctgaagg cctcttcact tataaatgct tccccagctg ccagtacgtc
    17761 tttcatttgg atcgaatcga tgatttcagg aagatcaaat aaagttcgat cgccaaataa
    17821 actttgcgta aattgattgg caatatattc gatcgaattt aatgattgga aatattgtcc
    17881 aagcattttc ttcttcagca aatcgagatt tgtttctgac acttccggat catcagcgaa
    17941 tccaagaatg atttctttga ctttttctgc tgctttctct ggttcgtccg tatctccgct
    18001 gaagtccgca aagtgaaatt cacgatccaa gctgaattca aaaccaaagc tgtcatcgat
    18061 aattccttga ttgtacatcg ctagatagtt tcgagaagta ttgcctaaaa tcatttggaa
    18121 caacagattg attgctgttt tatagcgtaa cagttctgtt ccttcttgcg gcaatgtgtc
    18181 taatccttta ataccaagta caaatttatc tcgtgtaatg gctgcttcca atgcactttg
    18241 tttgatgatt tcttttgtgt tttcagggaa ataacgtaca atttcttgct ttggagggaa
    18301 attttttgct tcttggtttt cccgaataag tttcatcaat ttctcaggct ccatcttacc
    18361 aactacaaat aaaaccatat tgcttggctg ataaaacgtc cgatagcacg tatacaagtc
    18421 ttgagctgtg attttgtcga tactttcaac cgtgcccgca atatcgatat gcaatgggtg
    18481 tgtaggatac aagttattta gtatgccaaa aaacatccgc cagttagggt cgtcttcata
    18541 catttggatt tcctgaccga tgattccttt ttccttgttt acagtttctt ctgtgaagta
    18601 aggtgcttgt acaaaatcga tcagagtcgt cagattcttt tctacctgat ccgtcgtaga
    18661 aaacagatag ctggttttcg taaaacttgt gaaagcattg gcggaagctc cttgtttccc
    18721 aaataattga aagacatcac catcttcttt ttcaaacaac ttatgttcta aaaaatgggc
    18781 aattccatct ggaactttca ccttttcttt ttcaccatag ggaataaatt cgttatcgat
    18841 cgaaccataa ttcgtactga acaaaccata tgtcttgtga tagtcatttt taggcaacaa
    18901 atacacggtc aaaccgtttg gcagtacttc atgataaagt gtttcattga tttgctcata
    18961 ttctgtttta ttcatttgca tttcctcctg ctaaaaagaa gattgcctgc aattcgattt
    19021 gctcagctac ttgttgtatc tctttgatcg ttacgctctc catacgtttc aaccattctt
    19081 catcagataa ttttgtttcc ggcagccagc tgtccaaaaa agaagcttcg attgccgctt
    19141 gcggagagtc tagagaaagc agatattggt ttctcagcat tgcttttgtc tgagacagtt
    19201 ccaactctgt tatttcacca tttcgcaaac tttctaattg ctcgtgaatc agatgaagta
    19261 cttgatttcg gttcttttca tcgataccgg tttggacact catgaatcct cggaacgtat
    19321 ccacgctact agaggcataa taagctagac tttctttctc tctgacattc atgaaaagtt
    19381 tagagtgagg aaaaccgcca aataaaccgt taaagaccat tagcgcaaaa cgttctggtt
    19441 catcgtaata cacatttgtc tgataagcta ggttcagctt tgcttgaacg attggctcac
    19501 gtacttgtcg ttccttcacg atattcactt gaggttgggt ataaaacaga tctggataaa
    19561 ctgtttcccg cgactcaaat ggtaattgcc caactgcttc agctgctttg tccggatcaa
    19621 catcgccgac aacaaaaatg tcgatttgat catttgccat catttcttga tagtaggacg
    19681 ctagcgaact agcagtgatc ttgtccaaat cttcgactac gcccaaccct gggatctttt
    19741 gttccgggct gttttcaaaa taaagttctt gcaaggcata ggaagcaaaa gtttgtttat
    19801 cttccttcaa actttccaaa tatagacgca gattgttctt ttccaagtca aacgtcaact
    19861 gatcaaactg atgattttta atatttggat aaaataaaac ctcttttaaa aaatctaccg
    19921 cttgagaaaa aaggtttgga tcattgacat attcaccatt cacaaaactg atccctgcgt
    19981 ttagccaatg taaatttcct ttttttctaa ctgataatcc aaagcttgcg ccataaagct
    20041 ctgcaagttg cg
//
LOCUS       DADGKS010000052        19507 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.052, whole genome shotgun sequence.
ACCESSION   DADGKS010000052 DADGKS010000000
VERSION     DADGKS010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.052"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(460..1089)
                     /gene="udk"
                     /locus_tag="JXV47_001973"
     CDS             complement(460..1089)
                     /gene="udk"
                     /locus_tag="JXV47_001973"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HAX1487997.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1173..1868)
                     /locus_tag="JXV47_001974"
     CDS             complement(1173..1868)
                     /locus_tag="JXV47_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="noncanonical pyrimidine nucleotidase, YjjG
                     family"
                     /protein_id="HAX1487998.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1881..2597)
                     /locus_tag="JXV47_001975"
     CDS             complement(1881..2597)
                     /locus_tag="JXV47_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HAX1487999.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2927..3532
                     /locus_tag="JXV47_001976"
     CDS             2927..3532
                     /locus_tag="JXV47_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HAX1488000.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3857..4180
                     /locus_tag="JXV47_001977"
     CDS             3857..4180
                     /locus_tag="JXV47_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAX1488001.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4362..5732
                     /locus_tag="JXV47_001978"
     CDS             4362..5732
                     /locus_tag="JXV47_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HAX1488002.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5862..7163)
                     /locus_tag="JXV47_001979"
     CDS             complement(5862..7163)
                     /locus_tag="JXV47_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAX1488003.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7393..9384)
                     /locus_tag="JXV47_001980"
     CDS             complement(7393..9384)
                     /locus_tag="JXV47_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HAX1488004.1"
                     /translation="MATTHNTKKISMAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDKVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9528..9794)
                     /locus_tag="JXV47_001981"
     CDS             complement(9528..9794)
                     /locus_tag="JXV47_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAX1488005.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10304..12430)
                     /gene="pnp"
                     /locus_tag="JXV47_001982"
     CDS             complement(10304..12430)
                     /gene="pnp"
                     /locus_tag="JXV47_001982"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HAX1488006.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12618..12887)
                     /gene="rpsO"
                     /locus_tag="JXV47_001983"
     CDS             complement(12618..12887)
                     /gene="rpsO"
                     /locus_tag="JXV47_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HAX1488007.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13138..13701
                     /locus_tag="JXV47_001984"
     CDS             13138..13701
                     /locus_tag="JXV47_001984"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAX1488008.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13954..14475)
                     /locus_tag="JXV47_001985"
     CDS             complement(13954..14475)
                     /locus_tag="JXV47_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HAX1488009.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14478..15320)
                     /locus_tag="JXV47_001986"
     CDS             complement(14478..15320)
                     /locus_tag="JXV47_001986"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HAX1488010.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15313..16038)
                     /locus_tag="JXV47_001987"
     CDS             complement(15313..16038)
                     /locus_tag="JXV47_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HAX1488011.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16214..16510
                     /locus_tag="JXV47_001988"
     CDS             16214..16510
                     /locus_tag="JXV47_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488012.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17078..18670
                     /locus_tag="JXV47_001989"
     CDS             17078..18670
                     /locus_tag="JXV47_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750719.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAX1488013.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18683..19423
                     /locus_tag="JXV47_001990"
     CDS             18683..19423
                     /locus_tag="JXV47_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAX1488014.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         5580 a         4001 c         3702 g         6224 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaaa cagttggctg gtgactgttc aaaaagcaga atccttgctt
      421 ttcaaacggt cgcagtccgt tcaactgttt cgctgcgcac tatttatggt ttaagaaact
      481 agctactttt gttgtaatca aatcaatagc aacgtggttt tctccgcctt ctggaacaat
      541 gatatccgca tagcgcttcg ttggttcgat aaattgatga tacatcggtt taacaactgt
      601 caaatattgt tcgatcacgg agtccaatgt gcgtccccgt tcttccatat cccgtttgat
      661 acgacgaatg atacgaatgt catcatctgt atctacgtat actttgatat ccatcaagtc
      721 acgcagacgt tcgtcttcta aaatcaggat tccttctaga atgatcactt cttttggttc
      781 ctgaatgatc gttgcctgac ttcttgtatg cgctacatag tcatacacgg gtttttcaat
      841 ggctttatag ttcagtaagt cgcctacatg ctgaatcagc agatcattat caaaggcaaa
      901 tgggtgatcg taatttgtgt tcaatcgttc ttcaaaactc aaatggctct gatccttgta
      961 ataagaatct tgttcaagca tcatgatgga atggtccggg aagttgttga aaatcgcacg
     1021 gctgacactt gtctttccgc ttccggatcc acccgtcaca ccaatgataa ttggcttgct
     1081 ttttgtcatt gactaaaacc tctttcgtat ccgttttttc attctaatct attatagcga
     1141 aaaaacacga aaatgctata tttttctgaa aattaatcct tttcaatttc caataatgaa
     1201 taaagttcct ctaatgaatc gattcgataa gtaggctgga tttcttcgat ttctggtaat
     1261 ttatttctat tgaaccaaat cgtatcgatc cctgccatat ttcctccttt gatatcagaa
     1321 gtcaaagaat caccaatgat cacagtttgc tttttatcaa aattaggaat gtgggaaaag
     1381 acatgatcaa aaaattcttt catcggcttt tgcgctccga cagcttctga gacaaagata
     1441 tccttgaagt aatcaagcat tcctgcatct gttaatcgcc gatgttgcgt gtgcgacaca
     1501 ccgttcgtca caatataaag atcagcatgc ggatggacct ttttcaggat ttctagactt
     1561 cctggaacaa gatcatgacc ttggttcaag tagtggcggt agcgtttttc catttgatca
     1621 ctatctactg ttttcccaaa ttgctggaaa agtaacccaa aacgactgcc tattatttct
     1681 tctcgtgata gtctgccttt ttcaaactcc tgccataaat gatgattcaa agccttatag
     1741 ctggtttcga tttctggtgt caatgtgatt ccttgttctg caaacaaagc acttaaagca
     1801 ttggcttcag ttaattgaaa atctaacaat gtatcatcta catcgaacaa taaagtttta
     1861 tatttcatct ttttgacctc ctatttaaaa taaatactta actttttcat ctctgctaat
     1921 gtcaacgatc gatactcgcc tactcctagc tgttcatcta attccaatgg tcccatgctt
     1981 agccgtttca atgcggtcac tttctttcct tgggctaaga acatcttttt gacttgatgg
     2041 aattttcctt cttggatcgt caataaaacc gtactttggt gcttgtctgc tttgagtatt
     2101 tttaaatcag ccggcttaca ttgataccca tcagcgaata cgattccatt ttcaaatgct
     2161 gttacgtctg ccggtgtcac cctttcgttc acaactactt gataagtctt tgaaaccttt
     2221 ttttctggaa gtagcatttc atatcccaat tgtccattcg aagtgatcag caatagtcct
     2281 gttgtatctc tatctagtct tcccactgga tataatggtt ggaaacgatc ggcacttgca
     2341 atcagatcga ttactgtcgt cttttctgga tctgatacag ctgtaacagc tttttcaggt
     2401 ttattgagaa gataatagga ctcatttgtt tctaagtgtt cacctgctac ttcgatttga
     2461 tgcagtaaac tatctacatt tcgattttgt cgaaattcga ctgtgccatc tatcatcact
     2521 tgcttcaaag caaacagccg cttcatttcc ttgcgtgtcg tttctaattt ttcttctatt
     2581 aatttatcta aacgcatgct gtttcctttc ttattactac taattaatta taccttgaat
     2641 attcttgctt gcaaatacat catcatagtt attccttgac ttaattaaca gttcacgtta
     2701 cggttaaata gtaaagtgaa ttggatttct catacacagc gtaatgacct ggtggagaaa
     2761 agttgaatcc tgactttcta aggggagatg cgcgcatctc tccttttgcg cttttttaag
     2821 cgccctgcct tcgatgatgt gcacgagatt agcctttaga attcacttaa ataaaatctg
     2881 tccgttacca aagcagacag tcacatttta aggaggaatt ttggttatgt cagtatcatt
     2941 agaagtaagt aaaagagaag tacgtccccg ttcattaaga aacaaacttc gtcacgaagg
     3001 gaaagttcca gctgttgttt atgggtataa agtagaaagt acccctatct cattcgatgg
     3061 tttgacacta agcaaattgt tgcgtgaaca tggagcgaac acagtcatca cgatggacat
     3121 cgatggacaa aaagtcaata cattggttca caagatccaa acgaacactt ttaccaatca
     3181 tttcgaacat gcagaatttc tatctgtaaa catgtcggaa gaaacagaag tcgaaacaga
     3241 agtcgttctt gttggcgaat cagtgggtgc taaatctggt ggagtgttag ctcaaaactt
     3301 gtatacagta gtcgtatctg ctacaccaga caaattgcct gaacgaattg aagttgacgt
     3361 gacaaacttg gaattaggtg attctattac agtagccgat cttccaaaaa acgacgatta
     3421 caaattcgtg accgacagtg aagagcaaat cgctgctgta gtcgctcaaa gtgaagaaga
     3481 aagcacaggt gaaggtggcg aaccagaagt gatcggttca acagaagaat aatactgaaa
     3541 caatcaggtg gtgttagaag cggcgggtca gcagctttta acacgccttt tttatttcta
     3601 atcgtttatt ttcatatggg gcttccactt ttgtaaatgg ctttacaaac gaaaaatcct
     3661 aatttaccaa gcttttcctc gcatactttt atcgtacctt tataaaaatt tatactttga
     3721 aaaaaagtat tcaattattg ttgcattttt cctgattctt tattagaatg aaccctcgtt
     3781 gaagtaagta tttctagttt atcctaggat taattataaa aataaaacat tcgttgattc
     3841 gaaggaggtt aaacagatgt ttgaaagttt tgatagcagc cgcaaccgtt acgcttcagt
     3901 tggtgtcgta tcaagtttgc cagatgaatt gattgacagt atatggttta ttattgacct
     3961 agatcttaag ggagtcattc cattagaaaa tatattaacc tttgatttga tcgaaaatcg
     4021 tggaaaagtg acgatgcatt tttctcaagc aggaagcaat gtggaaatgg atattgattt
     4081 gccgtttgcc tattcgaacc aatttcctgc tcaagtatac gcctatgatg acggtacgag
     4141 agaaacgatc cttttaccaa gtgagattag acaatattaa ggtgatagat aaacgtggat
     4201 gtcccttatt ttacagacca ggccaagttg ttgattcttt gactcaattc ttggcttctt
     4261 tttatggagt ttcataaatt atcattgatt tctaattggt attctcagga taaacgctat
     4321 atactactaa ctaaatttta aagatataag gagtttaaaa gatgcgcgat ttaacaaaag
     4381 gaagccccgc taaactgatt ttgatgttca ctgttccttt actgatcgga aatgtttttc
     4441 agcagttcta caatatgatc gatatgatca tcgtgggtca gacgctaggt aaaaatgcgc
     4501 tggcagcggt tggtgcaact ggaagcctga catttttgat cattggcttt gcccaaggtt
     4561 taacagctgg tttagccatt attaccgcac aacgttacgg tgcaaaagat tatcggggtc
     4621 tgaagaaaag ttttgctgct agtgttgtca ttagtcttgt cgtcactgtg attttaactg
     4681 tcctaagtct cctgtttatt cgtccgatgc ttcaattgat gcaaactcct cctgaaatac
     4741 ttgatcaagc acaaacattt atttcaatta ttttattagg gatctttgca tcagtcagtt
     4801 tcaatttgct ttctaatgtc attcgcgcac ttggtgacag ccgcacacca ctattctttc
     4861 tgatcattgc ggtcatcatc aacgtcgtac ttgatttgat ctttattatc tattttggca
     4921 tgggtgtgga aggtgcagct attgctacag taatcgcaca agtttcttcc agcgtactgt
     4981 gtctagtgta tatcaagaaa aaaatgcctt tgttacagtt acgcaaaaaa gatttcaaat
     5041 ttgaaaaaga agagtttgct gtacacctaa atgctgcttt gccaatggcg tttcaatctt
     5101 cgatcatcgc tgttggtgct atcgtgttac aagcagcact aaatagtcta gggacagatg
     5161 tcgtagctgc tcaagccgct gctggtcgta tcgaccaatt tgcaaatcag ccgatgatgt
     5221 catttggtat tgcaatggca actttcactg cacaaaacta tggtgcgaaa gaatatggcc
     5281 gaatcttgca aggggtacgt caaactttac tgatgagtgt cggatttagt ctcttagcag
     5341 gtgctatcgt cattttcttc ggtcatttct ttgttcaatt gtttgttagc ccatcagaaa
     5401 cacgtgtatt tgaattagca caaacctact tcaatatcaa tgggtctctt tactggatct
     5461 tagcagtcct gttcatttta cgctacacac ttcaagggct tggacaaagc aagatcccta
     5521 cgatcgccgg tatgatggaa ttgcttatgc gttcttttgc agctatcgtt cttacaggaa
     5581 tgtggggata cccaggagca gcagcagctt ctcctttagc ttggatcggt tctgttgccg
     5641 tgttgcttta ctcttatatg cgttcgatga aacaattgaa acacatgggt gaagaggaac
     5701 atttcacatt agaacatgca gaagcaagat agccttgatt aaaagaaatc gttgcggcta
     5761 aaaatgaaaa cttttattga aaatatcttc ttcgtttacc gaaaacaggt tttttagata
     5821 acaaaaaggc tgtgacaaaa aatgtcacag ccttttttct tttattctat ttttctttcc
     5881 gtggactcta ctttgaaata atcgatatgt gcatgctggt attctaatac cgtgaaacgg
     5941 aatgatgcaa tctcaatgat tgttcctgct tttatttctt tatatcggct agaagcaaag
     6001 cccgcaagtg tagtaaaatt cgtttcttca aactctggaa tctctacatg aaaataacgc
     6061 tggaaatcat ctaatgttag tttgccggag atgatataag agccatctga ctgttccgct
     6121 atcaatgctt cgtccaaatc tgtctcatct cggatttccc cgacgatttc ttctaaaata
     6181 tcttcaatcg tcactaagcc gcttgtccct ccgtattcat cttttaagat agcaatatgc
     6241 tttccctttt ttcgcatgat cgtcaataat ttttttatag ggatcgtttc agttgttacg
     6301 atcggctctt caatcaactg ttctactgtc agctggtcat ctttataaga ttgcttgatc
     6361 aaatctggca aggtgacata acctaaaaca ttgtcttttg attctaagat aaccggatag
     6421 cgagtatgtc cttgttcaat cgaagctttt atcgcttctt tgacggtttc tgaagcttcg
     6481 aatacttgca tggacgtacg gtctacttgt atatcttttg ccaaggtatc atcaaattca
     6541 aacacgtttt ccaaataatg atattcttct ttggtcaact ctcctttttc ataagaattc
     6601 aatgcgacta atgtcagctc ttcttgagac aatgtctctt ctccttcaga tacgagacgc
     6661 acacctaata gcttccctag ccctgcagct gaatgattca atacccaaat aaaaggaaac
     6721 attactttat aaaaataatg aagtggttta actacgaaca agacgacctt ctccgtattg
     6781 acgatactat agctcttagg aagcagttcg ccaataacca catcgatata cgtaactaaa
     6841 ataaatccca gcgccacaga gattgtactg ctaatagccg aactaaaagg tagtttaccg
     6901 atcactggtt ctagtaaagc cgcgacagat ccttcaccga cccacccgat gatcaaaccg
     6961 gttagcgtaa ttcctaattg actagctgat aaatagttat ctaaatggtg tgtaacatga
     7021 agagctagct tggcgttctt tacattttcc ttttctagtt gttccaatct tgatcgtctg
     7081 attttcacta aagcaaattc acttgctaca aaaaatgaag taattgcaat catcaaaaat
     7141 aaaataatga aattgataac catattctcc cgcctttctc tttttctatt gtaccctttt
     7201 tctacaaaaa gattgaaaat aatgcgtatt catatttagg aataaaaaag gagatgcggc
     7261 atttttcagc cacatctcct tatcacttca aaatcattgc gttacttgtt gctaaacagc
     7321 tttttcatga cctctgataa acggtgttca agtagctgac attcgacatt agttcaggtc
     7381 aaagcgctac tttcacaacc gctctttcaa ccatgttttc cgagtatttc caatgataag
     7441 cggaacagtt tcatgtttta cttcgctgta ctctagccca aaccatgttt ctggcgaggt
     7501 agcgattttt ttgattgcca gttttgcctg catgatttga cgttgccatt ttcctagagt
     7561 tgtcacattg gaaactactt tatcaatcag gacaaattgg aaatcgccaa cttctcgccc
     7621 tggtgtcaga gagtatcttt gtggctgttt tggcaaacgg ccttgtttca tcaaatcatg
     7681 gatgacttgg cgaacatata cgttgatttc ctgttggacc ctgaaaccta agaacagatt
     7741 cacttggaca ataaaatcag tgtccatcat atctacttga tattctttcg tatatggctc
     7801 atccgtcact tccacatgaa caaaccaata gactcgtgct cttttaggcc gtttatctaa
     7861 aatcgaatag atgaactgtc ggccaacttt atcttcagcc atatcaggaa ccaagaagac
     7921 cacatttgtc tgatagattg gtaaagaagt atcatcacgt aattctctaa gctgcgggat
     7981 ataatctctc aaagacacat cctcggttga cgattcgcga ataatgttcc cttgttccca
     8041 aataaacatc acgactaaga tgatcaaacc aatcagaacg gctacaaaac cgcctcggaa
     8101 gaatttgaca acacttgaga taaagaaaac gacttctatc gcaccgaaga aaaaggtaac
     8161 taaatatgca agccaacgag aatgcccatt ttggataaga taaaagtaaa gcagtgctgt
     8221 tgtcatcaac atcgtcacag tgatcgatag accgtaagca gcttccatat gatgagacgt
     8281 tcggaatgtg acaaccacta gagaacaggc gatccataaa atcagattga ctgctgggat
     8341 atacatttgc ccgatactgt tcccaggata catgatcttt aaccgaggca gcagtttcaa
     8401 cttgattgct tctgaaacta gcgtaaacga acctgtaatc aatgcttgcg aagcaatgac
     8461 tgcagcgact gttgcaaaag caacgccgat cacgatccaa ctttgaggca tcatttggaa
     8521 gaatggattc aggttcttga tttgctgtgc ttcagggttt tgataaacat tcaacaacca
     8581 cgcagcctgc ccaaaataat tgataaccaa acaaattttg acgtaaggcc agctcagacg
     8641 aatatttcgt ttgccgacat gtccaagatc ggaataaagc gcctctgcac ctgtcgtagc
     8701 caggaaaata tttccaagaa tgaacaagcc taatttgtta tctgcactaa aaagcagctg
     8761 gatagcataa taaggattca gtgcacggat aactgtccag tcttgactga agttcattaa
     8821 tcccattacg cctaaaaaag taaaccaagc gaacatgatt ggtccgaatg cttttccgac
     8881 aatatctgta ccaaagcgtt ggaccatgaa taaaacaaaa ataataacta aagtgataat
     8941 gacgatcacg ttctggttat taccgaaccg gtcaaaaaac tgcggaattc ctcgcaagcc
     9001 ttcaatcgca gtcgttaccg tcacagcagg ggtcaatacc ccatctgcta gtaaggcagc
     9061 tcctccgatc attgcaggaa tgatcaaata tttcccacct tttcggacaa gtgtgtagag
     9121 tgagaaaatt ccaccttcac catggttatc tgcattcaat gcaatcacga catatttgat
     9181 tgttgtcagt agagtcaatg tccaaaaaat caatgagact gatccgataa caaaatcagg
     9241 attgattcct gacaatccgc cattatcttc aacaatcgat ttcataacgt aaagcggact
     9301 tgtcccgatg tctccgtaga cgactcccat cgctacaagc aggccagcca ttgatatctt
     9361 tttggtattg tgcgttgttg ccacgttttt ccctcatttc ttgttatatg gatatccttt
     9421 aggtaagctt gaatgataga tgatattctt atccatgaca cccgctttcc taaattgctt
     9481 ctaattatcc aagtaacaca ctgaagtgtc aacttatttg aataaaatta ttctttcttt
     9541 ggacgttctc tgatacgtct tgccacaaat gaataaagag caaggcaaaa aattgcaccc
     9601 aataatgctg gtatcaaata aaaaccgccg agttccggtc ccagtggtcc tagtaaaaat
     9661 tcgccgagcc aactacctaa aaaaccgata atgatatttc cagatacgcc tcccgggact
     9721 tcctttccta aaattgcgcc agctatcaaa cctaatatac cgccgataaa taacgaccat
     9781 aaaaaattca gcatctcctt tccctccttt atccatattt ctcactttta ttttacgctt
     9841 tattcagaag gactccaaaa atatgcgcca agaaactcca gaaaaaaaga agttgtaaca
     9901 aaagtgttca gcttatttcc gtagaagctg cttctggaac accgtgaatc agaggttgtg
     9961 aaatcagcgg tttgacctga gtattagaga aacaaacgga aaaatagttc ctcatatttt
    10021 gccgtttttt gagctaatat cgagggacag ctgattgaac atcgtttatt ggagaggttg
    10081 taaaaaagct gttctgcatc aagtaataag aacagccaag taaaaacagc tcctaatgtt
    10141 tttaacttgg ctggacttat taccgcagat gcaagctttt gaacaccgtt tattcgaaaa
    10201 aaaaggactg tgacacggct tttgtcacag tccccttttt tcgaataatt attgtccccc
    10261 tgtcaccttc acgatcacaa gtacattatt cctatgaatt aaattatttt tcttcatttt
    10321 tcgttgaacc atcttcgttc aacattgctt ttcttgacag atttacgcgt ccttgtttat
    10381 cgatttcagt tactttcaca aggatctcat cacctagttt aacaacatct tcgactttat
    10441 tgacacgatc gtttgctaat tgggaaatat ggacaagtcc atcttttcct ttgatcaagt
    10501 tgacgaatgc accgaatttt tcgatacgga caactttccc tagataaact tcaccaactt
    10561 tgacttcttt ggtcaaatct tcgatgatct tgatagcttt tttgatcatt tctgcatcag
    10621 ctgaagcaat acttactttt ccatcttgat cgatatcgat tttcacacca gtttcatcga
    10681 tgattccgtt gatcgtatcg ccgcctttac cgataacatc tttgatttta gcaggttcga
    10741 tctggatcat ttcgattttt ggtgcatatt ggcttaattc ttcacgtgga gcagcaatcg
    10801 ttgaagtcaa ttcttctaag atttccatac gtgcttgttt tgcttgagtt aatgcttcag
    10861 ttaggatttg ttctgtgatt ccttgaatct tgatatccat ctgtaaagca gtgataccat
    10921 cttttgtacc ggcaacttta aagtccatat cgccaagatg atcttccagc ccttggatat
    10981 cagttaggat cgtatagttt tcaccatcag aaacaagtcc catcgcaata ccggcgactg
    11041 gcgctttgat tggtacacct gcatccatca atgctaatgt gccagcacag atacttgctt
    11101 gggaagaaga accatttgat tccaatactt ctgctactaa acggatcgta taaggaaatt
    11161 cttcttctga agggattact tgtgctaacg cacgttcacc taatgcgcca tgtccgattt
    11221 cccgacgccc tggagagcct gcacgtcctg tagaaccaac agaaaattga gggaaattgt
    11281 agtggtggat gaatcgtttg ctgacttcca cccctaaacc atcaatgatt tggtgctctc
    11341 ctagaggtgc gagtgtacaa gctgataaag cttgtgtttg tcctcgtgtg aacaaacctg
    11401 atccatgtac acgtggcaat aagctgacct ctgatgacaa tggacggatt tcatccaatt
    11461 tacgcccgtc aggacggatc ttatcgatgg tgatcaattc acgtacgaca tctttttcaa
    11521 gatcttctgt gatttgttta acttctttca acaagtgatc ttcatcttca tgacctgcaa
    11581 atttctcagc ataagcttcg cggatatcga tcttcacctg ctcgatatta tcttcgcgag
    11641 caagtttttc ttcagtcatt actgctgctt tcattgtagc gtaagaagca tcaaagattt
    11701 cttttttcaa tacttcatca acttgcagta aagtcacttc cattttttct ttccctactg
    11761 cttgaacgat ttcttcttgg aaagcaacta actctttgat agcgtcaaaa ccaaacagca
    11821 atgcaccaag catgtcttct tctgaaactt ctttcgcgcc gctttcaacc atattgatgg
    11881 cttgtttcgt tccggcaaca gtcaattcga tatctgtttg ttctgcttgt tctactgttg
    11941 gattcaagac gtactcgcca tttacacgac caacttctac gcctgcgatt gggccgtcaa
    12001 atgggatatc tgagattgat agtgctaaag aagaacctag cattgctgcc atagctggcg
    12061 agcagtctgt ttctacactc atcacgatgt tcgttacttg gacttcatta cggaagcctt
    12121 ctgcaaacat cgggcgaatt ggacggtcga tcaaacgggc agtcaatgtt gcttccgtac
    12181 ttggacggcc ttctcgtttg atgaaacctc cagggatttt ccctgctgca tacatttttt
    12241 cttcataatt gatcgttaat gggaaaaagt ctgtatcttt tgcttcttta gaggccacag
    12301 ctgcacttaa gactactgta tctccataac ggactaaaac ggctccgttt gcttgttttg
    12361 ctagctgacc gacttcgatt tgtaagggac ggccgcccca tgtcgttttg aatacttgtt
    12421 tttctgacat aacttctcct tttccttctc gtgaaagcaa gacgctacta aacaaatgaa
    12481 aactgccgaa agccgtcttt tgagcagctt tcatttggtt agtaggagtc catctagctt
    12541 gatcacggaa ttttacttaa ttgatatacg agtaaaaaaa gtgagattca tgtgaatccc
    12601 actctttttg actaaaatta acgacgcaag cctaaacgtt tgatcaattc gcggtaacgt
    12661 tgaacgtcag ttttacgtaa gtaagctaac aagttacggc ggtgaccaac ttttttcatt
    12721 aggccgcggt atgaatgatg gtcttttttg tgcacgcgtg catgttcatt caagtggttg
    12781 atttcttcag ttaatacagc gatttgtact tctggagaac cagtatcccc ttcatggcga
    12841 gcgtattcgt tgatgatttc attcttgcgt tcttttgaaa ttgccatttc tttcacctct
    12901 ttcgattatt cccctgcgac tgagtaaaac gttggtgatt cgcttaacca agtggcaggt
    12961 catgtgccta gagcacacag ctatacttta cctgaaaccg ggttgaaaat caagtagtta
    13021 atcattaaga aaaggtagtt ttcaaacaat cttactacta cttttccatt tttgtggtaa
    13081 actataatgc gaaaatagac ttgaaacaca gtcttttaag aaaggggtac atattccatg
    13141 attacaatgg atgatatcat tcgtgaagga aatccgacct tacgcgaagt tgcaaaagaa
    13201 gtttctcttc cattaagcga agaagatatc tctttaggaa aagagatgct tgagttctta
    13261 aaaaacagcc aagatccaat caaagctgaa gaactacact tacgaggcgg tgttggctta
    13321 gctgctcctc aattagatat ttctaaaaga atcattgctg ttcacgtacc aagtcctgac
    13381 ccagaggcag atggaccttc tctaagtact gttatgtata atcctaaaat tttgagccat
    13441 tctgttcaag atgcttgttt aggggaaggt gaaggctgtt tatctgttga tcgagaagta
    13501 ccaggatatg ttgttcgcca tgccaaaatc actgtgtctt attatgatat gaatggtgaa
    13561 aaacacaaga ttcgtttgaa gaattatgaa tcgatcgtcg ttcaacatga aatcgaccat
    13621 atcaacggtg tgatgttcta tgaccacatc aacgatcaaa atccatttgc actaaaagaa
    13681 ggcgtattgg tgatcgagta gagaattggc aggttccttc gatactatgc tacaagaaag
    13741 ctttataaaa aaggggagtg ctcaaaagct gcacttccct tttttatgtt tctccactaa
    13801 tcgaaattta gatagacatc tagaaatcgc aattccaaaa aattctgtgt attggatacg
    13861 catcttttct tattttttct tatttcttcc atatgggtgt ttatctcaga gatgatagaa
    13921 tagtttctag gataaaaagt agcagctacg atgttatcct tcgtagagga ttcctgcttc
    13981 agctagtttt tgtttgatgt ttttcagcat atgcttttct gggtagcgga tcgtatgcag
    14041 atggatgccg cctgttaatt cggataacaa agtagcatta cttttttgat aacgtctcat
    14101 aaaggaatcg atatcttgtg gcgttttgat gtgcaaagtt cctgctaact caccgtaaag
    14161 gggatgttcc acaattacat caatgatttc accaccattt tcaacgatta gtctcagttc
    14221 ttcttctgtt tgatcttttc catgctggac agcgatttta ctgatgtgcc cagtattggt
    14281 ttcttctgtt tcgaggatat aacctcttgc tgttgccacg atacttttac ctgcagctcg
    14341 tagtaaagca atatcgccta caatgatctg acggctgact ccaaaagttt tcgcaaactt
    14401 gctagcactc actggttttt ctgtatttgc caaggtttgc atgatttgtt ttcgccgtgt
    14461 ctctccttcg atcacactta ttcctccttc attttgtttt ggtattcgcg cgagtgtttc
    14521 atcaaatcaa catacgtgtc tgttattgtt tccttatatc ccttattttt cagcagacta
    14581 acaactttat ccaatacttg ctgctctctt tttgcatcat aaactgcttg gttttcttct
    14641 tttttcactt gtcctatttt agttaccgta tccattcttt tttctaataa agcaaccaac
    14701 tctcgatcga tcatatcgat cttatgacgt aatgtttcaa gagactcttc tgttagttct
    14761 tcctctactg tcttgatgat acgagcagga tttcctgcaa tcactacatt gtcgggaaaa
    14821 gatttggtca caaccgaacc tgcgccgact actacgttgt cccctagagt gacacccggc
    14881 gtgacgataa ctcctccgcc taaccaaaca ttattaccga ttttaatggg ttttgcgtac
    14941 tccagaccgc tgttacgttt cactggatgt agtggatgcg tcgccgtgta aagctggaca
    15001 ttcggagcga acatgcagtt atcaccgatt tcaatcgtgc tgacatctaa aaatgtacaa
    15061 ttgaaatttg cataaaaatt ctccccaaca aatatattat atccgtaatc aaaattgata
    15121 actggctcca tatagatttt tttccctgta cggccaaaag tctctttcaa caattgggat
    15181 cgcagttccg ctgattctgc ttggttgatg atttggcttt gacttcttgc aaacatacgg
    15241 tcggcaacca gctcaggatc attggcaaaa taaagctcgc ctgcaatcat tttttctttt
    15301 tcggttttga attcagtcat aatctgctcc taattcttgt atttttttga aaacaaccgc
    15361 tccgtcttct tgaataaacg tataaggctc cgctaaataa acaggcgttt gattgattac
    15421 taagattttg gctgacggct ggcgaaactg taccagatca caaaacggat gaacttgaaa
    15481 actcgttcca acaatgacga tcagctctgc ttggctgacg gcataagccg cctgctccat
    15541 gactccatct tgaaaccctt caccatataa cacgatgtct gggcgtattt gtcctccgca
    15601 tgcttgatgt ttgtcgctgt gaagatattc tttccagtct accgtttgtt gacattttcg
    15661 acaatgacat tgatacagac tcccatgaaa attgacgagt tgcgggcttt tagcctttgc
    15721 gtgcaaaccg tcgatgtttt gggaaacaac ccaaacattt ttttctttcg ctagatgtgc
    15781 tatttccaaa tgaatgatat tgggttttgc ttcaggatga taaatctttt tgacaaattg
    15841 atagaattta tccggttcat tcaccattgc ttgatgactc agcaagtatt ccggctgctc
    15901 catcccgtgg tagattcctg acaaagatcg atagtctggc actccagaag gtgtggatac
    15961 ccctgcaccg gtcaaaaatg taatttgctg ataagctaat atctcttttg ctgcttcgtc
    16021 tactgttaat tgtttcatgt tttgtcacct cactttccat tatagcccat actcgaacaa
    16081 atttattgtt gaaaagtcag aaaaatggga ataaaaaagt gttatgggca tttgagcaat
    16141 ttatcacaat gttcactgac aaaagaatga aaacgtgtta caatactgct gtataaaagt
    16201 gaggtgaatc gatatgttac cattctttat ttattggggc gttattctgg cttgtatcgc
    16261 ctggttagcg ttaagcgttt atttctctgt tttttatctt gtacgcaaag aaaatggaaa
    16321 tctttgggct tttgctttat tcaacgtgat tgccgcaatt gttttagcca ttacattagc
    16381 cgtatatcga acatggggct ggggaatcac ccaatactca agtttgattt atctaatatt
    16441 agccatttat ggcgtcgttg ttcttttgca agcgatccta ggacgtgagc caaagaaagc
    16501 ggcagcttaa atgatcgaga tggaactgga cacaggaaat tttctgttct agttcttttt
    16561 ttattgtatt acatacattt ttgtgtataa ttatactatc gtttgcaatg gatagatgat
    16621 tcacattttg attgtttttt cggtaaaagt aaagatttct atatttatca gtattttttc
    16681 aaaaaccagc agttatagat tgacaaagcc tctcgagtat cgtaaacttt ttttgtataa
    16741 ataactgaat acgagatgcc tcaatcaatg aggtagaggt cgcgagaatc attaaccctg
    16801 tggagtgaag caaacatgga gaagcaggaa tagggaggat cgccgaaatg tgcacttttt
    16861 tgcttggagt gtatgttggg acgcaagtta agagcttgcg gactgtctta gcagtgatgc
    16921 taagttgcgc tatgttttgt gagaggttta tcaccttatg gaattttagc ggccttttta
    16981 tatctataaa tcggtcgctt tttatttttt cagataaagc tttaccgcat ttcatctaga
    17041 ccgctcgtgt atcatataat cagaaaggga gaaaaaaatg aaaaaaaata tggtttcagt
    17101 tgccgtacta tttgcttttg tcttctcact attcagtgtg ggatctctgg caaatgcaga
    17161 tgaaaaaaca ccgagcgatg agtttcgcgt aggtatggag gctgggtatg cacccttcaa
    17221 ctggtctcaa caaacagatg agaataatgc cttgccaatt caaggccaaa atagttacgc
    17281 cggcggttat gatgttcaaa tcgctaaaaa agtagcagat ggtttaggga aaaaattagt
    17341 catcgtccaa acgaaatggg atggtctggc tcctgccctt caatcaggca agatcgacgc
    17401 gatcatcgcc ggaatgagcc ctactgctga acgacgaaaa gaaattgatt ttaccgatcc
    17461 ttattacgaa tcacaattag tagtagtagt tcaaaaagat agcaaatatg caaaagcaaa
    17521 aagtttagca gatctttctg gagcaaagat cactgctcag ttaaatacat tccactatac
    17581 tgtgatcgat cagataccag atgtgcagaa acaacaagca atggataatt tctcagcaat
    17641 gagaacagct ttagcttctg gaatgatcga tggttatgtc agcgaacgtc cggaaggtgt
    17701 aacggcaact agtgtgaaca aagacttgga aatgcttgaa ttcagcggtg cagatggctt
    17761 ccagacaaac ccggaagatg ttcagatttc tgttggtatg cgtaaaggcg acccggatat
    17821 ccaaaaagta aaccagattc tttctggcat ctctaacgat gaacgaacca aaattatgga
    17881 ccaagcagtc aaagatcagc ctgctgcaac tgatagtgaa gaaaaacctg gcatcatttc
    17941 tgatttcact acgatttgga aacaatacgg caatatgttc ttacgaggtg ctggacttac
    18001 cttgttcatc gcattgatcg ggacagttgt cggtactaca cttggattac tgattggtgt
    18061 cttccgttcg gtacctgaat caggaaatgc actgactcgc ttcttccaaa aaatcggaaa
    18121 tgcacttctt tctatctatg tcgaagtatt ccgcggaaca ccgatgatgg tacaagcaat
    18181 ggtcatcttc tacggtctgg cactcgcttt tggcatttca ttgaaccgaa cgattgccgc
    18241 tttgtttatt gtctctctca atactggagc ttacatgaca gagatcgttc gtggggggat
    18301 ttttgcagta gatgaagggc agttcgaagc tgcgcaagcc attggtatga cccatggcca
    18361 aacgatgaga aaagttgtta ttccacaagt tttacggaat atcttgccag caacaggaaa
    18421 tgagtttgtt atcaatatca aagatacagc agttttaagt gtaatcggcg tagctgattt
    18481 gttcttccaa ggaaactctg cttccggtgc gaatttccaa ttcttccaaa catttacgat
    18541 cgtcgggatc atctacttag tcatgacctt tacgatcacc agaatcctgc gggcggtaga
    18601 aaagaaaatc gatggtcctt cagcttatac caagcttgaa gaaatcgaca attcaaattt
    18661 gcaggaataa ggaggaagaa tcatgaatga aaaaattatt gaaatcaaac atctaagaaa
    18721 aagcttcggt gaaaatgaag tattgaaaga tatcagcgta acagtcaata aaggtgaagt
    18781 tgtgacgatc atcggttctt ccggttctgg taaatctact ttcttgcgct gtatcaattt
    18841 actggaaaaa ccaacaggcg gcgagatcat ttataatgga gaaaatgtat tagctcctaa
    18901 atataattta cctaaatatc gaacgaatct aggtatggtt ttccaatcct tcaacctgtt
    18961 caacaatatg aatgtcttgg aaaactgtat gtctggtcaa acaactgtcc tgaaacgaga
    19021 taaagaaact gccaaaaaag tagcaatcga aaatctggaa aaagttggta tggatcgtta
    19081 tatcgaagcc aaaccagcac aattatctgg tggacagaaa cagcgtgtcg caattgctcg
    19141 ggcattatca atgaatccag atgtattgct attcgacgaa cctacttcgg cgttagaccc
    19201 tgaaatggtt ggcgaagtgc ttaatacgat caaagactta gcacatactg gcttgacaat
    19261 gcttatcgtg acgcatgaga tggaatttgc aaaagatgta tctgaccgtg tcatttttat
    19321 ggataaaggt gtgattgcag aagaaggtac accagaagat atctttgtcc atccgaaaga
    19381 agaacgtaca aaagaattcc tttcacgtat tttaaatgct taggatcaat agctgattgg
    19441 gacaaagagc tgcggtgttt accgcagttc ttttttatga attactcata aaaggtaaat
    19501 ttctgaa
//
LOCUS       DADGKS010000053        19323 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.053, whole genome shotgun sequence.
ACCESSION   DADGKS010000053 DADGKS010000000
VERSION     DADGKS010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19323
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.053"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..1121)
                     /locus_tag="JXV47_001991"
     CDS             complement(<1..1121)
                     /locus_tag="JXV47_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAX1488015.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSV"
     gene            1271..1831
                     /locus_tag="JXV47_001992"
     CDS             1271..1831
                     /locus_tag="JXV47_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAX1488016.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            1960..2337
                     /locus_tag="JXV47_001993"
     CDS             1960..2337
                     /locus_tag="JXV47_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HAX1488017.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            2270..4342
                     /locus_tag="JXV47_001994"
     CDS             2270..4342
                     /locus_tag="JXV47_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAX1488018.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(4553..5500)
                     /locus_tag="JXV47_001995"
     CDS             complement(4553..5500)
                     /locus_tag="JXV47_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAX1488019.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            5746..6210
                     /locus_tag="JXV47_001996"
     CDS             5746..6210
                     /locus_tag="JXV47_001996"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HAX1488020.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            complement(6272..7315)
                     /locus_tag="JXV47_001997"
     CDS             complement(6272..7315)
                     /locus_tag="JXV47_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HAX1488021.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(7692..8657)
                     /locus_tag="JXV47_001998"
     CDS             complement(7692..8657)
                     /locus_tag="JXV47_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HAX1488022.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            8891..9736
                     /locus_tag="JXV47_001999"
     CDS             8891..9736
                     /locus_tag="JXV47_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAX1488023.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            9927..11114
                     /locus_tag="JXV47_002000"
     CDS             9927..11114
                     /locus_tag="JXV47_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAX1488024.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            11120..11476
                     /locus_tag="JXV47_002001"
     CDS             11120..11476
                     /locus_tag="JXV47_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HAX1488025.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            11478..11816
                     /locus_tag="JXV47_002002"
     CDS             11478..11816
                     /locus_tag="JXV47_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HAX1488026.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            12211..13245
                     /locus_tag="JXV47_002003"
     CDS             12211..13245
                     /locus_tag="JXV47_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAX1488027.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            13238..13924
                     /locus_tag="JXV47_002004"
     CDS             13238..13924
                     /locus_tag="JXV47_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1488028.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            13948..14796
                     /locus_tag="JXV47_002005"
     CDS             13948..14796
                     /locus_tag="JXV47_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAX1488029.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            14993..15766
                     /gene="sufC"
                     /locus_tag="JXV47_002006"
     CDS             14993..15766
                     /gene="sufC"
                     /locus_tag="JXV47_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HAX1488030.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            15779..17065
                     /gene="sufD"
                     /locus_tag="JXV47_002007"
     CDS             15779..17065
                     /gene="sufD"
                     /locus_tag="JXV47_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HAX1488031.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            17062..18297
                     /locus_tag="JXV47_002008"
     CDS             17062..18297
                     /locus_tag="JXV47_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAX1488032.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            18284..18754
                     /locus_tag="JXV47_002009"
     CDS             18284..18754
                     /locus_tag="JXV47_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HAX1488033.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            18759..>19323
                     /locus_tag="JXV47_002010"
     CDS             18759..>19323
                     /locus_tag="JXV47_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HAX1488034.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPK"
BASE COUNT         6505 a         3643 c         4116 g         5059 t
ORIGIN      
        1 acactggagc cgatcatagg ccctactacg ttaccagttg cttggaaaga ttggttataa
       61 ctgaagatcc gtccagcagc ttgatgaggc gaatattttg tgatcaatgc ttggacagca
      121 gggagcagac aagcatcaga gataccaatc aaaaaacgta aggcagctaa ttgccaaaca
      181 ttcgtgacga atgccattgg gatataaacc agaatcgcaa aacccaaacc aatcgcaagt
      241 attctttcac tcccaatctt gtcacctaag cgaccaaatc ttggagcggc tatcaaagtg
      301 gcaatcccag gtatcgaagc aatgattccg ctgatcaacg taacattccc atgtccatgc
      361 agcaattggc gaatgtacag actgatgatt ggactaatgg aattgttgga tgcttggatg
      421 atcatcgttg tgacgaacat accgatgacg acgtgtggat atttcaagtc tttgaaaatc
      481 tgtttggcag aaaccatgtt ttcttttttc actgggacaa atttttcatg gacgaaaaac
      541 agactcaaca agaagacgaa aaataagatg atccctgtaa tgaaaaaggt agggcgatag
      601 ccaaacgctg aagcagagat cccgccaaga agcggtccaa gtaatgttcc tgtaacagaa
      661 ccagttgcta aggttccaag aacttgacca cttttttctt ttggcgtccc agttgcgaca
      721 agggcagtgg cattactgat ataaccagaa aaaatccctt gaagcagacg caatgcgact
      781 aattgataca cactagtcac gcaacccatc aaagaaatga cgattgccat tcctaatgaa
      841 gcacgcaaca gcatcaattt tcttcctttt tggtcggcta attttcccca ccaaggagag
      901 ataagcgtag tcaccaagaa agtagatgaa aaagtcaatc cgctccaaaa gttcaattgt
      961 gacgtactat aattacctaa cgtatctatg taaagtgaca taaaaggcat gactaaacta
     1021 aatccgatac cagccataaa tgttccaaac cataagacaa acaagttttg ttcccaagtt
     1081 tctcttttcc taaataattt ttcctttatt cttgcagcca attagactcc ttctttctga
     1141 aaattttcat ctacagctct ttattataaa ctacaatatg tagtttatca atgaaagtct
     1201 cttttttctc tttctttttc gtggtaaact gaaagagtga aggatttatt ttatgagagg
     1261 aaacatggaa atgaaaaaaa gaaatctgtc tcaagagaaa atcatcgact gctttcgaga
     1321 actagcagaa gagatggatg ttcagcaaat aacctttcag catttagcca aacgcttgga
     1381 tatcaaggct ccctcgctgt ataaccattt caaaaatatt cgtgatgtca aaacagcgct
     1441 aacagcgaaa cttctgcagg aacttaatga ccagctgcga cgggctcttg tgggaaaaag
     1501 tggtcaggaa gcactgcaga tctatgcaga aacttatcga tcctttgctt tttcaaatca
     1561 agcagtgtat gagttactga tcagtgtacc gcataccaat gaagctgttt tattagatgg
     1621 aatccatgaa acgaatcaga tcattttgca gatatttgag gcttttcaat taacgaaaga
     1681 agaaaaagtt catcgaagca gggaacttcg tagtatgatc cacggttatc tttccttacg
     1741 ttttttagga tactttacaa aagaaccaac aatcgatcca gaagacagct atttttggat
     1801 gatcaataac tttatcgcta ctttgcctta aacaatcaga ttcatttgta acaattttaa
     1861 gatgttcatt aaatgaccct tttataagag aaaattcttg caactttctt gaaaagtgac
     1921 taagatgagt ctagaaaagc tgaaagaagg agcacgagta tgtatcaagt aattaccatg
     1981 ttcggggaca atgagccttg gtggtttttt gaagactggg aagaagatat tgaagaagaa
     2041 gaaacattcg agtctttcga agaagcacga caagcgtacg aaaaacaatg gaacgaaatc
     2101 catcaaaatt atgaatatat caatgcaaaa agtaactttc tcagcgcctt ttggaatgac
     2161 ggagatgagc gctggtgtga agagtgtgac gatgatttac agcaatacaa gggacttgcg
     2221 ttgttgaaaa atcatcagcc catcacagta gaaagcagaa aggaatttta tgaaacaact
     2281 aattctagcg gaaaaaccaa gcgttgcgaa agacctaagc aaggtgcttg gtgctaatca
     2341 aaagcacaaa aattattatg aaggacccaa ggtgatcgtt acttgggccc ttggtcattt
     2401 attaggattg aaaatgccgg aagatctgaa taaggaatgg cagagctggc aaatggacac
     2461 gttgccaatg atccctaaaa aactaggaat caaaccactt cctaaaacag gacatcaatt
     2521 aaaagcaatc aagcagctgg ctcagcgaaa agatgtctca gaagcagtca ttgcgacaga
     2581 tgccggaaga gaaggggaac ttgttgctcg ctggatctta gagtatgtgc atttcaataa
     2641 accagtgaag cggttatgga tctcttctca aacagataaa gcaatcaaaa ctggattcaa
     2701 gcaactaaga cctgcgaaag aatatgatgc attgtatgaa tctgctcttg cccgggcaaa
     2761 agcggactgg ctggtaggat tgaatgtgac cagagcctta actgtgaagt acgcggataa
     2821 tttatcagca ggccgtgtgc agacaccgac actagcatta gtgagagacc aagaaaagaa
     2881 aatcgagcag ttccgtccac aaacgtattt cacgatcacg ttgcaagctg gaaaagaaca
     2941 agccaaaatg cttcaaaaaa atcaatttgc tttaaaaaca caagaagaag cacaaaaact
     3001 tgttcaattg atcagtacaa gcaaaggaac tgtcacagaa gtccaagaaa aattaaaaac
     3061 ggaatctgcg ccattgcctt atgatttaac agagatccaa agagaagcca atcaacgcta
     3121 tggctattct gcaaagaaaa cattaagtct tgtacaaagt ttgtatgaga cccataagat
     3181 cgttacttat ccgcgtacag acagcaaata tctgacaaat gacatgaaaa gtacgatgaa
     3241 agaacgattg caagcagtca gcgactttgc tcctgaggtc aagcagtatt tgaaaaacgg
     3301 agccatcgtc caacagacaa aagtattcca agacagtaaa gtgaccgatc accatgcact
     3361 tttgccaact gaaaacagag cacgttatga aaaattaagt aatgaagagc gaaaaatcta
     3421 tcaaatgatt gtctctcgtt ttttaggact gtttgctcaa ccccataaag tcagccaaac
     3481 aaaagttacg gttgaatttg gtaaagaacg attcattttt cggcaaaatc gtgtcgtcca
     3541 agcaggatgg aaaggcgaaa ctgaaactga gacggaaaca gtcaaatggg aaaaaggaat
     3601 gagaatcaat cccgatttcg ccatcaaaaa agaactatct gcaccgccta aaccattgtc
     3661 agaagcaagc ttgcttggtc aaatggaaaa atacagtctg ggaaccccag ctacgcgtgc
     3721 agagattatc gagaaactaa tcaaatctga actgatggaa cgtacccctc aaggactgca
     3781 agtatctcct aaaggtaagc aattattagt attggtaaat ccctctttag taacaccaga
     3841 tttgacagaa agctgggaaa aagaccttga agctattgct gcaggaaaga aacaagcagg
     3901 aaccttcttg aatggaatcg aaaaagaaac aaaacgcttg gtgaatgaga tcaaatcaag
     3961 caaacaagaa tatcaagatt tctcgattac ccaaaagaaa tgcccagaat gtggggccaa
     4021 tctgcgcgag aaaaacacac gtgacggcaa aatctatgtc tgcaccaatt cagattgcaa
     4081 ctaccgcaga agaaaagatc caaaagtctc taatcatcga tgcccgcaat gtcaccggaa
     4141 aatggaaatc atcgaaggta aaaacggtgc ttatttccgt tgtaaatacg atggaacgac
     4201 agaaaaattg cttgataaaa aagagcagaa gaagaaaatg accaaacatg aagaacgacg
     4261 cttgctgaaa aaatatgcac aagcagaaga accagaagaa agcccattag cagcagcact
     4321 aaaagcagca atgaagaagt aataagatat gaaagaggtt gtgatagaag tggtcagctt
     4381 caagaaataa gaaggaattt acgaaaattg cttctcaaat ttttgtgaaa tttcggctta
     4441 tttccgaaga agctacttct ggaacaccat ttattcggaa aaaaggactg tgacaagact
     4501 tttgtcacag tcctttttca tttaaaaaaa tgtttacttc atttgacgta tattattggt
     4561 gaggcttcaa ttcatttggc ttcacttttt ctgtttctct tatgatataa acaggacgct
     4621 gtttcgtttc taagaagatt ttcccaatat atttcccgat gattccaaga cataacaatt
     4681 ggattccacc aatgaacagg aagatcgaga ccatggaagg ccatcctgat gtaggatcac
     4741 caaacaacaa tgcccgcaaa ataatgaaca aaattgcaat accagaaccg acacaagaca
     4801 aagcgccgat aaatgaagca atcgttaacg gtgcatccga gaagttcacg ataccatcaa
     4861 tcgagtagtt gaataatttc cagaaggacc aagatgtttc gccagccaca cgttcgcggt
     4921 tttcataaga aatatattct gttttaaatc cgacccagct aaataatcct tttgaaaatc
     4981 ggttgtattc tgttaattct aggacggcat ccaccatttg acgagtcatc aagcggaaat
     5041 cacgagcgcc atcgaccatt tctgtatcgc tgattttatt gatcaactgg tagaattttt
     5101 tcgcaaagaa actgcgtatc gcaggctcgc cttcacgagt cgaacgccgg gtgccgacac
     5161 aatcgatatc agaagtagtg atccggttga tcatctcagg aagcagttcg ggcggatctt
     5221 gcagatcaac atccatcacg gtcactaaat ctcctgtaga agcttgcaat ccagcgtaca
     5281 gagccgcttc tttcccaaaa tttctggaaa atgagacaaa gcggacataa ggataagctg
     5341 aggctagctt cttgattgct gctaacgtac cgtcttttga tccgtcgtca ataaacaaat
     5401 attcgaactc atgggcacct ttgaattttt caacctcatc aaaaaaaaga ggaacagttt
     5461 tttcttcatt aaaacatggg acaacaattg atactttcat cgtttctatc ctttcaatcg
     5521 tatgtttata tatggtttac attcaaaatt taataaacct taaataacac ctttaaaatt
     5581 tgattttacg taaaagaaca ggtattcttt ttgtaaacta acgtatttag tttaccatgt
     5641 ttcctcggtt tatcaaactt ttaagaacaa tttttattag ttggcaagta gttttggata
     5701 gagaaaaagg aggaagttcc agtctattga ctaggagcaa acaaaatgaa aatacacaca
     5761 cctatcggct ttttatggtt agatgcagat gaatccggat tgactgctgt atcttttcag
     5821 ccaatttcag aaagcgaatc agcgaatcag cgaattttaa cgcgcacaca agaacagttt
     5881 gaagaatatt ttgcgggaaa aagaaaagaa tttgatgttc ctttatctat aaagagaggt
     5941 acgccttttc agcaaaatgt ctggaaagct ttgtcgacca ttccttatgg agaaatccga
     6001 acgtataaag aagtagccgt tgctgttgat agtccgaaag ctgtgcgagc gattgggcag
     6061 gcaaatcgaa ccaatccatt gccaatcgtt attccttgtc atcgagtgat cgggcaaaat
     6121 ggaaaactga caggatatat gggaaacgca atagatgggg ttgaaatcaa acgccaattg
     6181 ttgttgttag aaggatatct gcaaaattaa aaacagttgt gattcggaca ttgttccatg
     6241 cgagaatcac aactgttttt tcatgttcat tctaaacttt gatcagccaa ataaatagta
     6301 aagccatcac tgtttggaga agcccgacag ctaatccata agataagaag cgtgtacctt
     6361 ctttcatgaa ttttgcaaag tctaaacgca gaccaattgc cgctaaagca gtgatctcaa
     6421 accagctgct gataaaatgt gccgattggt caataactac aggtaaagaa aacaagctgt
     6481 tgaccaaaca aaagatcaca aaccctaata cataccaagg aagcggtaat tttcgttttt
     6541 tctgcgtatc agttggcgtt tcaaacagag ctggttgttt cttgtgcatg aatttttcaa
     6601 acagatagac aacaacaacg agcatcataa tacgtagaat cttaaatagc atggcgaatt
     6661 cgacaacaga attgtcaagt aagcttgccc cagcgactac ttgaccaaca gattggagtg
     6721 taccacccaa aagtgcactt ttttcaatga gatttccacc aaacaactgt aatccaagaa
     6781 aagggagagt caacatcatc acagtaccca gtagattgac tagtgtgatg atctgtcctt
     6841 tttcttcctc tttcgcatgg atggaagggg cgattgaagc aatagcagaa gaaccacaaa
     6901 cagcgtttcc tccagccatc atcaaagaag aagtatcgct gaattgcagt tttttaccaa
     6961 tcaagtaagc accgatgata gtgactgaca tttgcagtaa cacaaaaaca attcctttta
     7021 caccaatttg agcaatcgtt tgagctgtga cagttgcacc tagtaaaaaa acagagaatt
     7081 ctaatagttt gctttcagca aattttgtgc cgattgctag aacaggctgt ttaaaaaaag
     7141 tatttcctaa taaaataccc aataaaatag caatagtcgc tccacctaac tgtggcagat
     7201 aaatagcaag aagcctgctg aaggcagcga tggcaaaaga aagcagtaaa ccgggtaaga
     7261 tttcgcggac cgctgaatcc tttacagatt ttattggatg tgacaatgat ttcatttgat
     7321 cggttccttt cgtcaataaa tactaaaagc atactcgaac atagtagcac taaaccagta
     7381 ttttgacaaa agaacaagag gtcgtgacaa aagtcttgta cgacctcttg tttcgaataa
     7441 acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa atttgagaag
     7501 caattttcgt aaattccttc ttatttcttg aagctgacca cttcttttac gacctcttgg
     7561 taaacggtgt tcaaaagctt gcatctgcgg taataagccc aaccagtaca aaaacatgaa
     7621 cagctgtttt tgtttggccg ttcttattac ttgatgcaga acagcttttt cacaacctat
     7681 tgaatcgatt attaagcgat ttttttagaa acaaattttc catgtttgct atgttcttta
     7741 attaagaaac gtacgtaatg agcaagaacg tagaagacaa ctacacttgc aaacagacat
     7801 tccgcaactt ttaagaaatc caatacgcta ctatagatac ctaaactgtt gaagtaatga
     7861 acagtagtaa atatagctgt tgcagagata acaagcggga atgtaaaggc tgcatagctt
     7921 ggataaaaac gaagcttgaa caaacgtgga agcatagaca gcacaacgaa atacaatact
     7981 tgagataaag cgaacaatgc tacgacaaga taaaaattag gttcagcaaa gtttttaaga
     8041 taacctgtta ggcaaagaga accaggtgct gcaacgatcg taatcagcgg acgtgtcgga
     8101 tgagccatat ttcttacgaa aaagacacgt ttgatgatga tcggcaataa gaacgcatag
     8161 cagatcaatg aaatccaaaa gaaaattttt ccaataagtg ggaagaagtt cccggcagtt
     8221 acagtgatga ccccaaatcc aacgtaaatg ataaaccagc ttggataaat tgcttcaatt
     8281 gaaagatcag ctttgataac atggtgataa ttgaaataaa agacaaggat cacttggaag
     8341 ataacagcgc acagccaaat gaatttgaca attggtgcaa tactttcata tgaaacaaaa
     8401 taagtacaaa taaccatgag tgacatcgta aaagttggtg aaacggaggc gatgattgga
     8461 tcatgcaacg tttgtttcgt gtgttcgaat aagataaaca atttaacaaa aatgaatatc
     8521 ataagaatca tagagatacc gccagttaga ttgcctaaag caacatggtg atagtcttta
     8581 aacagatttc caagggaagc taacccaagg atcaacccgc agatcgggat cggaataatt
     8641 ttcaaaaagt tcttcatata taatattctc ctttttattt aatagatttt agtaccaaga
     8701 tgaacgaata cattgtaaaa tgaataggaa tgtatgatta cgagcaagca gacagctgat
     8761 tgtcttcatc taagttacta gttggatcag caactgtttt gttgtacatt tctattatag
     8821 atggtttttt gtatatttaa atcaaatagt ttttatagta attatcataa aaagttatgg
     8881 aagtggtgcc atgtttaagt tattaacgac ttttcgagca gtatatgaaa caagaaattt
     8941 ttccagagca gcagaagtac tgtttttatc tcaaccagca gtctcgaatc aaatcaaaca
     9001 gttggagcgg gaattgaata tcgatctttt tcaacgtaac ggaagaaaag agatgcttcc
     9061 aactaagcaa gccgacttat tatatgaacg gacactggtt ttgttagaag aatgggaaga
     9121 aactcagcaa aaattgctca atgaacaaaa tgaagaagaa gtatgtcgga tcgttgcttc
     9181 ccacaccttt gctgtctatc ttttgcctca gttgatgaaa catctgatca aaaggtttcc
     9241 taaagtgcat tttgagatcg aaatcacgaa ttctcatgaa tcattagaac aagtagcgaa
     9301 acatgaatcc gattttggtt ttatcgaaaa gccattagag acttccggcg tacaaagata
     9361 ctctttgatg gaagaccagc tagtcatcgc tggggaccca aaaagcaaat tgtggcttgt
     9421 aagagaagca aactctggtg tttttcatta cacgcagcgt tattttgaag agatgaatat
     9481 ccaagataag aagatgatcg tgaaaagtaa cgatgtaatt gttgcgttgc tgaaggaagg
     9541 aatcggtcgc tcgattttgt ctaagcgctc tgttccagaa aatgtgccaa tgactccgtt
     9601 gaatttccat cgatattttt atttcatcca acgaaccaat ctggtttctg atcagctgct
     9661 agagattgcc gaagagatcc ttcgatacaa tgaaagcaca gaaacttctc acagcgagga
     9721 gaatctcagc tggtagataa ttgcatgtat caaaaaaagt tctatgatac actaaagata
     9781 agcagtaggc ttttgtactg catttgctca agcaactgca caaacggaaa gttaattttt
     9841 cccaaatgtc tatggaaaga ctttccatta tctaactgga ccgctataat aatcagcagt
     9901 atggttttta agaaaaggga tgaaacatgg aaaaaaaatt aaaagcttcg aacgataatc
     9961 gtattgatta tggcgtgatt ttaccagtct ttctgttatg tttgattggt ctgctctcat
    10021 tatatgtagc acttagccat gatccgaaca atccagcagt cttgaaaggc gtagggatgc
    10081 aagttgtctg gtatttagtt ggagcggcag caatcgttgt catcatgcat ttgaattcca
    10141 aatggatctg gaaactgact ccttaccttt atggtttggg gttagtggta atgggactct
    10201 tgctcaaatt ctatgatcag aatttagctg cttcaacagg gtctaaaaac tggtttcgat
    10261 tcggtgcgtt tactttccag ccagcagagt tgatgaagat tgcgtacatc ttgatgatgg
    10321 cactgatcgt aactaaacat aatacgcaag taaaagaacg gacgatgaaa tcggactttt
    10381 ggctgattgg gaagctcttg atcgtgacaa taccggtttt agcattgatc atggcccaag
    10441 atgactttgg aacgatgctt gtctttcttg cgatctttgg cgggattttc ctgatgtctg
    10501 gaatctcttg gcgcatcatc gcacctgtag taatcttggc agtagtcgtt ggagcaggaa
    10561 cgatcttctt ggttacgact gaaggcggaa gagacttgct ttataaagtt ggattcaaat
    10621 cttatcagtt tgcacgtatt gattcatggc tggacccttt ccatgatacg tcaggaatga
    10681 gttatcagcc ggcccaagga cttttggcaa ttggtaccgg tggcttgttt ggtaaaggat
    10741 tcaacgtaag caatatctat gtgcctgttc gtgagtccga tatgattttt accgttatcg
    10801 gtgaaaactt cggctttatc ggtggtgcat tcgtcatttt cttgtatttt attttaatct
    10861 atcgtatgat tcgggtgtgt ttcgatacga ataatgaatt ttacgcctat atcgcaagcg
    10921 gtttgatcat gatgctgctg ttccatgtct ttgagaatat tggagcaaat atcggattac
    10981 ttcctttaac agggatccca ttgcctttca ttagtcaggg aggatcctcg attttaggga
    11041 acatgatcgg tatcgggttg atattatcga tgagatacca aaatgaagca cctgcaagat
    11101 cttcaaggag gtaagaaaat tgtacacctt ttactggtac ccgaaatgtt caacatgcaa
    11161 aaaagccaaa gcgtggttag accagcatgg cgttagttat caaaccgttg atatgatcaa
    11221 agaagtaccg aaggcctcaa cgattgagac ttggctagaa acgagtcaag taccaatccg
    11281 tcgcctgttc aacacaagcg ggatgaaata tcgggaactt ggactgaaag atcaagtagg
    11341 cgagtttacg gcttcaaaag cgagccaagt cttatcgaca gatggtatgc tgatcaagcg
    11401 accactgatc ttacgagagg accagcttgt tgcaattgga ttcaatgaaa aaatttatga
    11461 aggagaactg atataaaatg gcaggcaagc atttgaagaa aaaggacaac ctttggatct
    11521 tatttaatgg aaaagaatac tgtgttggtt tgacaaatga agcgcaagaa gaacttggag
    11581 acatcacgtt tgccaatctg ccaaaagcag gacaatcgct aaaaaaagat gaacctctga
    11641 tcgaagttga agcggaaaaa gcggtcaatg aatttgccag cccgctaacg ggtacagttt
    11701 cttctgttaa tgataaaatc ggtgaagata tcaatatctt gaatgattca gatgaaatga
    11761 atgcgtggat cttaagtttc aaagatgttg atccaaaaga atttgacgaa ttataaaatc
    11821 agaaaatcac ttgaaaaaag ttgacactga ttcttccagt tgctataatc ataagcaatc
    11881 ctatatgaaa cgagaaagct ttgaaaagaa gagtacatgt cacggacgtt tgaagagagc
    11941 cctgtttgct gaaaatgggt aacgaaaatg agatggaaga tggtcttaga gcagagtaag
    12001 cgagcgtaag caaacttact acgggagtgc ccgttacagc gcgacagtat acggaaagaa
    12061 gctaagtcca agtactggaa gaggctgtta ttgcgaagta acggtaaatc aaggtggtaa
    12121 cacggaagtt caagctttcg tccttttgct taaggcaaga gggcgaaggc ttttttgttt
    12181 gaaaaatcat aagagaaaga tgtgaatggc atgtcattaa tccaactaac gaatgtcaaa
    12241 aagacattca atgggaaaaa cggaaacatc caagccgtca atgacgtttc actaaacgtt
    12301 gaaaaagggg atatttatgg aatcgtcggc tattctggcg caggaaaaag tacattagtc
    12361 cgtctcctga atggacttga gcttcccacg agcggcgaag tgatcgtaaa cgatcaagat
    12421 attacaaaat taaaaaacaa agaattacgt acattccgaa agaaaatcgg tatgatcttc
    12481 cagcatttca acctgttatg gtcaagaact gtacttgaaa atatccagct gccgctggaa
    12541 ttagctggcg taccaaagag caaacgtaaa gaacgggcag aagaactgtt gcgtttagtc
    12601 gggttagaag gacgcggaca agcatatcct tcacaacttt ccggcggaca gaaacaacgc
    12661 gtcggtatcg cacgagcatt ggcaaatgat cctgagatcc tgctttgtga tgaggctact
    12721 agcgcattgg acccgcaaac aacagaagaa gtattagact tattgttagc gatcaataag
    12781 aaattgaatt tgaccatcgt cttgatcaca catgaaatga atgtgatccg caaaatctgc
    12841 aacaaagtcg ctgtgatgga gttggggaaa gtcgtagaag aaggagacgt attgactgtc
    12901 ttcagacaac cgaaaaaaga agtaaccaaa cgctttgtac aacaagacat cgaaccagaa
    12961 gctgattcga cagaactatt agctgaactc atcaaagaaa atccaagcgg ccgtttggca
    13021 actttgacct ttagcgaaag aaatgccaac gagccagtca tttcccaagc gattcgacgc
    13081 tataacatcg atgtcaacgt tgtgtatgga aagatcaaac aagtgaaaga aggttccttt
    13141 ggttcattga ctgtcttgat gactggtgaa accaaagaat tagatcaagc agaagtgttc
    13201 atcaaagaac aaggagtagg aattgaggtg atccatcgtg gataaaagct tttcagaaac
    13261 atatctagat tttaaacaaa tcaacccgga aacgatgaat caggctatcc ttgatacact
    13321 atatatgaca ttaatctcaa tggtcttagt gacgatcatc ggattagttt tgggattgat
    13381 cctttactct attggacgca aaaacaaacc gtatgctcga atcatttatg gaatcgtatc
    13441 gatcatcagt aatattttcc ggtcaacgcc atttatgatc ctgatggttt tgatcattcc
    13501 atttactaaa gcaatcgtag gcactatgct aggtgcgcaa gcagccattc cagctcttgt
    13561 tttatccgca gcaccatttt atgcccgtct agtagagatt gcttttcgtg aagtcagccc
    13621 tggtgtactg gaagcagcag atgcaatggg agcaagttac tgggaaatca tctggaaggt
    13681 cttgatacct gaaagtattc ccgcattgat ttctggatta acagttacaa cgatctcgat
    13741 gatcggattt actgcgatgg ccggcgcgat cggcgcaggt ggacttggag gtcttgcttg
    13801 gcaggaaggc taccagcgtg gtaatctaac agtgacattc gttgcgactt taattatttt
    13861 actaatcgta tttatcgttc aaggaatcgg tgatttctta actaagaaaa cagacaaaag
    13921 ataataggat atagggggat gtaggatatg aaaaagaaaa tttttggatt tgcagcagcg
    13981 cttttgctga ctgtaggatt agcagcatgc ggtaacaaca gcgacagcaa agattcagca
    14041 aataaagcag acgacacgac attgaaagtc ggcgcttcac cgacaccgca cgcagagatt
    14101 ttggaacatg tgaaaccatt attgaaagat gaaggaatcg atcttgaaat cgtcaaattc
    14161 gatgactatg tattaccgaa ccaatctttg gaagaaggcg acattgatgc caattacttc
    14221 cagcatattc cttatttgaa caaagaaatc aaagaaaaag gatatgactt tgtcaatgcc
    14281 ggtgctgtcc acatcgaacc aatgggcttg tactctaaaa aagtcaaaga tgtttccgaa
    14341 ttaaaagatg gtgcaacaat cattacttca aattctgaat cagactgggg acgcatcatc
    14401 acaattctac aagatgctgg cttagtcaaa gtcaaagatg gagtagatct ggaaacagca
    14461 acattcgatg atattgaaga aaaccctaag aacttgaagt tcaaccatac gatcgaccca
    14521 tcacttttag cttctacgta ccaaaatgat gaaggtgacc tagttgcaat caacgcaaac
    14581 ttcgcttacg gcgcagggtt gaatccatta gaagatgccg tattgcttga aaaggacaac
    14641 tctccttacg tgaatattat tgcgactcgt aaaggtgatg aagacagtga caaaatcaaa
    14701 aaactgattg aagtgcttca ccgcaaagaa gtccaagaat ggatcacaga caaatggggc
    14761 ggctctgtta aaccagtaaa ggctgatgca aaataaggta tggaacaaaa aagatgagaa
    14821 ataagtctgt aatggcttat ttctcatctt ttttatacct attctaattt agaaatcaaa
    14881 attgtttaat aataaataaa agatatttga ttttagtaag gaaggtcatt gcgcttcatt
    14941 ctcaattagt ctaaaatgag tgagaacgaa agagaatttg ggggtataat gcatgtctgt
    15001 cttagaaata aaaaatctac atgtgtcgat cgaggaaaaa gaaatcctta aaggcgtaaa
    15061 cctaacaatg aaaaccggag aaatccatgc catcatggga cctaacggca caggaaaatc
    15121 taccttatct gccgctatca tgggcaatcc aaactatgaa gtaacagaag gcgaaatttt
    15181 gtttgacggg aaaaatgttt tagacttgga agtagatgaa cgtgcgcgac ttggcttatt
    15241 tttagctatg caatatccaa gtgagatacc aggtatcacg aatgcggaat tcatgcgtgc
    15301 agcgatcaat gcgaaacgtg atgaaaacga caaaatttct gttatggcat ttttgaaaaa
    15361 gttagatgaa aaaatggctt tactaaatat gccagaagaa atggctgaac gttatctgaa
    15421 cgaaggtttt tctggcggag aaaagaaacg gaatgagatc ctgcaattgt tgatgttaga
    15481 acctacattt gcaattttag acgaaatcga ttcaggtctg gatatcgatg ctttgaaagt
    15541 cgttgctaaa ggagtaaatg aaatgcgcgg agacaatttc ggtgcattga tcatcaccca
    15601 ctatcaacga ttattgaact atatcacacc tgatgtcgtt cacatcatga tggaaggccg
    15661 agtagtcatg acagggaatg ctgacctagc taaacgtctg gaagcagaag gctacgctgg
    15721 tatcagtaaa gaattaggaa tcgactataa agaagaagaa gcgtaagggg gagcaagaat
    15781 gaaagaaaaa aactggctcg attatcttga cgcggtaaat gatttttctt taagtaaagg
    15841 cgaacctgat tggatgagaa ccttccgtca agacgcacta gcgaaagcag atgaactgcc
    15901 attgccgcat atcgatcggg tgaaattcca tcgctggtcg ttatttgatg tgaaagaaac
    15961 acaaaccatc agtgaaacag gcacgattcc ggcatttgat gcaatgaaag acaatcctgt
    16021 gcttgtccaa caaggttcat ggacgatttt tgaacaactg cctgtggaat tagcagaaaa
    16081 aggagtcatt tttaccgact tgttcactgc aatgatcgaa tatccagaac tagtccaaga
    16141 atattatatg aaaaaagcag taaacatgaa cgaagaccaa ttgactgcac tccatgtagc
    16201 ttttatgaac agcggtattt tcctgtatgt gcctaaaaat gtcgtgatcg atgaaccact
    16261 cgagtcctta ttcattcaag atggcgcatc cgatgagcac ttcttcaagc atgtgttgat
    16321 cgtggcagat gaacatagtg aattttctta tctggaacgt ttccagacaa ccaaagaaca
    16381 agtagcaaaa tcatcaggta atatcatcgt ggaagtcatc gctaaagctg gttcaaaaat
    16441 caaatattca gccgtagatc aattaggaga aaatattact tcttatatga atcgccgtgg
    16501 gcacatttta cgagatgctt ctgtcgactg ggcaattggt gtcatgaatg acggtcatgt
    16561 gatcgctgac tttgactcag atttagcagg agaaggtgca cacgcagaag tcaaaatcgt
    16621 ggcaatcagc tcgggcagac aaatccaagg aatcgataca cgagtaacca ataaagcccc
    16681 tcatacgatc gggcatattt tgcaacacgg agtgatccga gaaaaaggaa cattgacctt
    16741 taatggtatc ggccacatct tgaaaggggc aaaaggtgca gatgcccaac aagaaagtcg
    16801 tgtcttgatg ctttctgata aagcacgtgg tgatgcgaat cctattcttt tgatcgatga
    16861 aaacgaagta actgctggac atgctgccag tgtaggacga gttgatccag aagaaatgta
    16921 ctatctgatg agtagaggat tgcataaaga agaagcagag cgcttagtga ttcgaggatt
    16981 cctcggttct gtcttaacag caatccctgt agaacaagtt cggaaagaat tagtcgaagt
    17041 aatcgaaggg aagttgaatg gatgatcgat gctaaaaagc tacgcaatga ttttcctatc
    17101 ttatttcaag acgtcaatga tgaaccttta gtttatctgg ataatgcagc gacgacccaa
    17161 aagccaaaac aagtactcca ggcattagcg tactattacg aacacgataa cgccaatgtt
    17221 catcgcggtg tccatacgtt agcagaacgc gcgacccatg attatgaaca agcaagagaa
    17281 aaagtacggg cgttcatcca tgcaaaagaa acagcagaag tgctgtttac tcgtggtacg
    17341 acgacaagct tgaattgggt agccagaacc ttcggcgacc gctatatcaa agcaggagac
    17401 gagatagtgc tctcttacat ggaacatcat tctaatgtta tcccgtggca gcagttggca
    17461 aaacgaacag gtgctgtctt gaaatatatc gaactaacag aagaaggctt cctggatatg
    17521 gaggatgcag cgaaaaagat tacggacaaa accaaaatcg tctccattgc tcatgtatcc
    17581 aatgtcttag gtgtcttcaa tcctgttcaa gaattagctg aacttgtcca tgaaaacggc
    17641 ggggtcatcg tagtagatgg tgctcaatct gccccgcaca tggccattga tgtccaagca
    17701 ctagactgtg atttctttgc tttcagcgga cacaaaatgt gcggaccaac aggtattggt
    17761 gttttatatg gtaaacgaaa atggttagaa gaaatggaac ctgttgaatt tggtggcgaa
    17821 atgatcgatt ttgtcgaatt atacgacagt acatggaaag aactaccttg gaaattcgaa
    17881 gcagggacac caaatatcgc cggcgctatc gcattaggcc atgcaatcga ttatttgcaa
    17941 aaactcggta tggacaatat ccatcgatat gaagaagaac tagccgctta tgtgttgcca
    18001 aaattacaag caattgatgg attgactgtt tatggtccac aagacccgaa ttttcggaca
    18061 ggagtcgttg cattcaattt ggatgggtta catccccatg atgtcgcgac agctttagac
    18121 atggaagggg tagccgtcag agcaggtcat cattgtgcgc aaccgctatt gaagtacctt
    18181 gaagtatcag cgactgctcg cgcgagcttt tatttctaca acacaacgca agacgccgac
    18241 cgtttagttg aagcaatcat ggcaacaaag gagtttttcc aacatgggac tatctaaatt
    18301 agacaattta taccgtcaag tgatcttgga tcattcttcc catccgcatc atcgtggaag
    18361 cttgactgac tcgacaagca agatcgaatt gaacaacccc acatgtggag atgtgatcga
    18421 attgcaagtc gatgtaaaag acggaatcat caaaaatatc gcctttgacg gcagtggctg
    18481 ctccatcagt acggcaagtg cctcgatgat gacagacgcc gtcatcggaa aatcaataga
    18541 agaagcagaa catttaactg tagactttct acagcttgtc caaggaaaag aagtcaaaga
    18601 tcccgaccaa ttaggcgatg ctgctatgct tggtggtgta gctaaatttc ccgctcggat
    18661 caaatgtgcg acacttgcct ggaaagcact aggaaaagca atggaaaacg atggtaccgc
    18721 agctttccat cattaccaca aggaagagga gtgagaacat gggcgtacca gaattagaag
    18781 aatataaatt cgggtttcac gatgatgtcg aaccggtttt cagtacagga gaaggcttga
    18841 cagaagaagt gatccgtgag atgtcaagaa tcaaaggcga accagaatgg atgcttgaat
    18901 tccgtctgaa atctctagaa acatttaaca aaatgccaat gcaaacatgg ggccccgacc
    18961 tttcagacat cgatttcgat gccatcaaat attaccaaaa accaagtgac aaacccgctc
    19021 gtgactggga agacgtacca gaaaaaatca aagatacatt tgaaaagatt ggtataccag
    19081 aagctgaacg agcttatcta gccggtgctt ccgcacaata tgaatcagaa gtcgtgtacc
    19141 ataatatgaa agatgaattc gaaaagttag gaatcgtctt tactgacact gactctgctt
    19201 tgaaagaata ccctgaatta ttcaaagagt acttttcaaa acttgtaccg ccaaccgaca
    19261 acaaattagc agcgctgaat tcagccgtat ggtcaggtgg gacctttatt tacgtgccaa
    19321 aag
//
LOCUS       DADGKS010000054        19224 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.054, whole genome shotgun sequence.
ACCESSION   DADGKS010000054 DADGKS010000000
VERSION     DADGKS010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19224
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.054"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..2110)
                     /locus_tag="JXV47_002011"
     CDS             complement(<1..2110)
                     /locus_tag="JXV47_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488035.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWRIYDILCNNGFTKQ
                     SACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLFN
                     AAGIKEPITSLDAQVRLLIWT"
     gene            complement(2107..2811)
                     /locus_tag="JXV47_002012"
     CDS             complement(2107..2811)
                     /locus_tag="JXV47_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAX1488036.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            complement(2823..5132)
                     /locus_tag="JXV47_002013"
     CDS             complement(2823..5132)
                     /locus_tag="JXV47_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HAX1488037.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            complement(5327..5791)
                     /locus_tag="JXV47_002014"
     CDS             complement(5327..5791)
                     /locus_tag="JXV47_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488038.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            complement(5791..6417)
                     /locus_tag="JXV47_002015"
     CDS             complement(5791..6417)
                     /locus_tag="JXV47_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAX1488039.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            complement(6424..6789)
                     /locus_tag="JXV47_002016"
     CDS             complement(6424..6789)
                     /locus_tag="JXV47_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HAX1488040.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            complement(6779..7117)
                     /locus_tag="JXV47_002017"
     CDS             complement(6779..7117)
                     /locus_tag="JXV47_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488041.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            complement(7107..7433)
                     /locus_tag="JXV47_002018"
     CDS             complement(7107..7433)
                     /locus_tag="JXV47_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAX1488042.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            complement(7414..7692)
                     /locus_tag="JXV47_002019"
     CDS             complement(7414..7692)
                     /locus_tag="JXV47_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HAX1488043.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETD"
     gene            complement(7694..9058)
                     /locus_tag="JXV47_002020"
     CDS             complement(7694..9058)
                     /locus_tag="JXV47_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAX1488044.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            complement(9071..9646)
                     /locus_tag="JXV47_002021"
     CDS             complement(9071..9646)
                     /locus_tag="JXV47_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HAX1488045.1"
                     /translation="MEMKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWD
                     DLSEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDT
                     TVARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYED
                     TEAALRSRDELEKNVEERKKLIKKINQALEA"
     gene            complement(9612..10799)
                     /locus_tag="JXV47_002022"
     CDS             complement(9612..10799)
                     /locus_tag="JXV47_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAX1488046.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            complement(10863..12590)
                     /locus_tag="JXV47_002023"
     CDS             complement(10863..12590)
                     /locus_tag="JXV47_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAX1488047.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            complement(12587..13039)
                     /locus_tag="JXV47_002024"
     CDS             complement(12587..13039)
                     /locus_tag="JXV47_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HAX1488048.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            complement(13151..13531)
                     /locus_tag="JXV47_002025"
     CDS             complement(13151..13531)
                     /locus_tag="JXV47_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAX1488049.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            complement(13528..13914)
                     /locus_tag="JXV47_002026"
     CDS             complement(13528..13914)
                     /locus_tag="JXV47_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488050.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            complement(13916..14194)
                     /locus_tag="JXV47_002027"
     CDS             complement(13916..14194)
                     /locus_tag="JXV47_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488051.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            14242..14970
                     /locus_tag="JXV47_002028"
     CDS             14242..14970
                     /locus_tag="JXV47_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HAX1488052.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            complement(15116..15592)
                     /locus_tag="JXV47_002029"
     CDS             complement(15116..15592)
                     /locus_tag="JXV47_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HAX1488053.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(15552..15899)
                     /locus_tag="JXV47_002030"
     CDS             complement(15552..15899)
                     /locus_tag="JXV47_002030"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488054.1"
                     /translation="MNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVLKIE
                     QNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIRGGV
                     CEISLVKRLPRTR"
     gene            complement(15886..16071)
                     /locus_tag="JXV47_002031"
     CDS             complement(15886..16071)
                     /locus_tag="JXV47_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488055.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            complement(16072..16344)
                     /locus_tag="JXV47_002032"
     CDS             complement(16072..16344)
                     /locus_tag="JXV47_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HAX1488056.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            complement(16341..16544)
                     /locus_tag="JXV47_002033"
     CDS             complement(16341..16544)
                     /locus_tag="JXV47_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488057.1"
                     /translation="MVKVREQFKIVSDEGNVYKIKIVNINEYREADHKYLVDLYMNDK
                     YLGEGFCGDSLFDDERILKEETE"
     gene            16669..16881
                     /locus_tag="JXV47_002034"
     CDS             16669..16881
                     /locus_tag="JXV47_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488058.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
     gene            complement(16914..17108)
                     /locus_tag="JXV47_002035"
     CDS             complement(16914..17108)
                     /locus_tag="JXV47_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488059.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(17121..17303)
                     /locus_tag="JXV47_002036"
     CDS             complement(17121..17303)
                     /locus_tag="JXV47_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488060.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKI"
     gene            complement(17930..18295)
                     /locus_tag="JXV47_002037"
     CDS             complement(17930..18295)
                     /locus_tag="JXV47_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488061.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            complement(18335..18637)
                     /locus_tag="JXV47_002038"
     CDS             complement(18335..18637)
                     /locus_tag="JXV47_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488062.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            complement(18637..18936)
                     /locus_tag="JXV47_002039"
     CDS             complement(18637..18936)
                     /locus_tag="JXV47_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488063.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
BASE COUNT         5392 a         4078 c         2980 g         6774 t
ORIGIN      
        1 atgtccaaat aagcaatcga acttgtgcat ctaagctcgt tattggttct ttaatacctg
       61 cagcattaaa taagttttga acataaactt ttccatccca tgttgctgga ccaacaagag
      121 gatatgaaga accatcccac tgaactaatc cgtatgctgg tccacctatt tgaacagtat
      181 caggatcaaa agttcctcct gtttcttgtt gaatgttccc caatattcca catgcagatt
      241 gtttcgtaaa tccgttatta cacaaaatat cgtatattct ccaagctctc ttttctgcat
      301 ctgtttttaa ttcatcagga tacccaccag gtgtttctcc tccgccagat ggaccgccat
      361 tttgtcctgg tatcacttct ttacctctaa cagtaagttt tccctgaata tctaaatcac
      421 cgaaataata tgcttttccg tttcctaata acacaaatcc tttttctgca gttggagaaa
      481 ttaaaatgta ttttccatcg ccatttgtac gtattaccaa agaattttcc tcaagaggtg
      541 taggtgttac agcatttgga aatggatttc ctgctgaatc tgttgttccg atcgttccaa
      601 tggattcttt tctattccag aattccatac cttttttggt tagctccatg atttttttgt
      661 tttcattcca aatttgaagc gtgcctttta caagttttaa cacatcacca taagcattaa
      721 aggaagtttc gaatacttct gcatttattg ttcctacttt gatgaagtca gcaacaattt
      781 ctccttttga tgtgatagca ataccgaacg ggccatttac tccgttgtct gaataaccta
      841 agccatttaa attccaacgc cacactcgct ttgcattcgc cacatttgga gtatccatga
      901 taagaatctc tgatggagct ttttctggac gaaaaacgac atgcccacca gaattaccag
      961 tgatccatgc cgtcgcattc aacacatttt gaactaacgt ttctgttcga ttgtcgattt
     1021 tctttttcaa ttcttgtgct tgagtattta ctgccgaagt gtacagtgat aaatcattac
     1081 ctaaaacaat atccttatat ttcccaagcg ttgggaaata agtgtattcg accatacgct
     1141 cttttatctc gatatctagc tctttcgccc taacatgagc gacatcacca aagtgtaaag
     1201 acgctagctc ttgatacatg tcaccgtatt cgagtgtgtg ttccaacgcc accatactga
     1261 ctgtatgagt agcttttggc tcatggatac gatcattgtc aaataaggtt ttgccccatt
     1321 tgatcaattc atcaactgtt ttacaatctc cgttttcacg tttggcaata cgtcgattct
     1381 cgttggttac tccatcaatt tctaaataac catattcgat aggttctttg tcttcatcat
     1441 aatcgttatc aggaacaccg ccaaccaaat acaaactatt gacaattgat tcttcatcaa
     1501 tttcttcttc gattgcttct aaattgatgc caaaatcaat ccgaaaacca ttatctgatc
     1561 caatctgttt taccagtttc aaatcatagt tatccatatc aagttccgcg ctagtcacgc
     1621 cagtcaaatt ttgattaccg ttatttgaac caatgattgc ttcaactggc gcgacttgtc
     1681 ttgctgtaaa ttggtgcgtt gtccctacat tcgaaagata gttaaatttt tgatcaaatg
     1741 ccaaactgtt tttaagattg gtcatgatct gagacccatt gccgttatcc gtaaacgact
     1801 tgacaataaa gttcttattg gccataaaac caatatgccg agctgttaca gaaacggagg
     1861 tcaaattctt tttgacatta taaatttcaa aatattgcca tgatccatct ggtaccttcg
     1921 cttttataaa atttcctttt tttaaataag agcgatactg tccgcttctt gaatagttac
     1981 cataaaaacg atattggcca ttcagcacac gattgatttc tggcaaatct tcccaatcaa
     2041 ctaacgacgc tccgttcacg ctcaaatcat ctggcatttt tttataagca taaataaatt
     2101 cttgcgtcac agatacacac tcctattcca aaaccgcact tctttaaatt ttccggatat
     2161 ttttacctga ttccattcag gctgcaatac tggccaatca ccacgcgtaa ataaattcaa
     2221 accttcttgt attgcttttc caagctgagt atcaaccacg attgttgcag ctaacgtatt
     2281 aagtattgtt aggcttttat caccgacagc gatcgttata tctcctccgt tcgattctat
     2341 ttccagatag ggatgtgcaa tttcgtcacc atgatcaaaa atatccataa cactagaatg
     2401 aaaaatttta ggtgcttcac cgatttttct tttgagtggc tgacaacgaa aagtaacatc
     2461 gaatgtataa aagaagcccc actcgttttc gaaagggact tctttatcca tgctgcagat
     2521 agcctctaga tacttgtctg gatcattatg tgtgattaat tggcttttac cagtgagcca
     2581 tcgtttgact tctctcagtt tcgaatgtgg aatagtgatc ccttctattt ccaaatcaaa
     2641 aggttcatag tcatcaaacg tctccgtcaa ttctccgctt cggccctgaa tcgtgtaagt
     2701 ttcgtatcgc ttgttcggca taatatctgg aagctctgcc tcaatgatgc aattcatatc
     2761 aattactgca ttccgatttt tccaaataaa atttggttca tctggattca taaattgtcg
     2821 actcaaatag gaacacctcc caaatcacga atagcctgtt tgtttgcttt agcaaattta
     2881 cgattcatac gatctaactc agatggattg tttgcatcga ctttgccaat gtgtatatgc
     2941 tgttcaatgc tacctccaga aactcttcca ctgatccctt tgcgtttttc ttcgtctgat
     3001 aatggagtaa ctgtggtttt accattcttg gcagtcagta actcaggtcc agcttcacca
     3061 acaatcgctt gtccattgat tagatgaccg ccttgtgcta aataaggcag ttttgaaata
     3121 gaaaatgatt ttccacctac accaggaacc cattttggta tctttatatt attcaatcca
     3181 ccaataaatc cattgatcaa tccaatcatg gcattaatag gagctttccc tacagcaaca
     3241 ataccatcga aaatacctcc aaaaatatca actagacctt gccatgcttt tgaccaattc
     3301 cctgtaaata ctccagtgat aaaatctaga aaaccactga aaattcgttt tccagcatta
     3361 taaaaattat tgaaatttgc tataacacca tcgaaaaatc caccaaaata accacttaaa
     3421 aaattaaata tttcaacagc tacatctgaa acacctttga agaaagaatt cactccatca
     3481 tgaaaccatt taacgttatt atatgcccaa attagtccag taactaatgc gccaatagct
     3541 ataactgcta atgcaaacca gcctcccgac attccaaata aaccagcaag tccttgccaa
     3601 actcctataa aacttttaac ttccccaacg atttttgtaa cagatcccat aagtgaacca
     3661 agaacgatta gtactggtcc aactgctgcc gctataccag caattgttat gatccaattc
     3721 tttgtatctt gatctagaga cccccaccat ttagagaatt cctgtaataa ggaagttgct
     3781 ttttcaaaaa aaggcaaaag gcttacttgg actgcttcac ctacgtcagc cattgctaat
     3841 tttgcattgt tcatagcttg atcggcttga tcaattgggt cgagagtagc atcgaatgtg
     3901 tctcctacag ctcccccact ttctccagca gtttttgcta aatcttccag gttcaaagta
     3961 cctctacgaa ttgcatcggc cattctagga ccgcctttag tcccgaatac ttctgctgct
     4021 gcattgatgg cttctgtttc agaacctgca ttttttacct tgtcttgtag ttcttctagt
     4081 ccttgactta aagattttcc gtctttcgca taagccactg ttgctttaga taaactactt
     4141 aaagctgcgc ttgaatcaac accagattgc tcaaattgtc caagtaaagt gaccccttca
     4201 ccaaagctca accctaattg tttaatttgt ggtgcgccat caattgcttt ttgcatcaag
     4261 tcgtctacag attgaccagt attctgcgat gttttcgttg ttacatcaag gacagaattc
     4321 aaatcatcat attctagtcc ataagcatca atagcttgtc gagcagatat tgctgattgc
     4381 gaaacatctg tatcattgat ttcagcgtac tgtaggagat aattggttga atcttccagt
     4441 tttttatcca tgaatccaaa ttgtgtattt acctcaccaa tagcttcccc aaccgtttgt
     4501 aaaggtaaat gagtatttga accaacgttt ttgaaagact gtgaaagtct atcagcttga
     4561 tcacctgttg ctccggtttt tgtaatgatg gtatcaagtg cctcgtcaac ttcaccaaat
     4621 gctgcaagtc ctgctgctcc tgccgctaca ataggcgcgg ttactccaac agacattttt
     4681 tcaccaacgc cttttacttt ctcacctgtt tcttcgattt tctggagttt ttttgctgta
     4741 tcaacagaaa cgtcaccttg ttctttaagt gcatcgttcg tctgttctaa tgctgtacga
     4801 agtttatttt ctccggtttc agaattgagt aattgtttat aaagtttttc tgattcagca
     4861 gaatattcac cggtttcttt gacagatttt tcatattcct ctctcagcat ttgagatcgt
     4921 tgttcagcca atcctaattg tttttctaat ttttgtttag ccgctcgcaa tttttctgtt
     4981 tgagttgcat ccttgtccat cgcagacact tggtttttgt actcggcagc ggctaagttc
     5041 atttctttgt tgatttcttt gattgttttc gaataactga cttcgccatt cgttttaaaa
     5101 ttaagaacga catcagattc tttaccagcc atttatctta gcgctccttt ctaccaccaa
     5161 ggcgatttat ccatagttac agattgaggt ggttcaaaat cggtgttttg ttgtaaccac
     5221 tgtaaataag atttgagcca caagttaggt gtagacttta aaaagaaact ctcactccaa
     5281 ttcaatagag tgagagcaac gtaaatataa aaactccaag gagttcctat ctcttccgat
     5341 tctttttgtt tttctttctt tttgcttgcg ctttttgaaa gtcttgtggc ttcttggatt
     5401 tttttaggtc ttccacctga aatgtctggc tagcaaaaat ttccatacag gtactataag
     5461 cagacaacac ctctccactc attcccaaaa atttgaaaat agtttctgga tcttcctcta
     5521 aaccaccagt acgcagcatg gcataaatca aggcacgcat gatttttaga tcactaggcg
     5581 ataagttagc agaagaaatt tgtccttctt ttttagatag catggcgttc atatcagatt
     5641 caaattgcga ataatctcca ccatacacat ctgctataaa ttccatcgtt tgcatagtaa
     5701 atgaaatagg gaattctgcg ccttgaataa ttacaacagc agaatttttt aagtcttcaa
     5761 cgtgaattcc ataatcagat aaccgagcca ttaacccgca cctccaactt tagccaatgt
     5821 tttccactgt tcttcatcgt atacaggttg agcaatgaat ttattaaata attctagaga
     5881 agctccgtct ctatttgaat caaaacttgc atacatcaca ttattgtatt tcagtccgat
     5941 ggaaaccaga tttgcagtta catcgtcaat ttttgtttct tcctctgcag tggcatactc
     6001 ttcgtcaatc acattggata gttgtgtatt aggataccaa actgcttttt taccgccatt
     6061 ttcaatattt ccaataaatc caaaggcgaa gtacggaaat tctcgtgcgg tatttttgct
     6121 aaacgttact ccgcttttag caactaatcc tttgatttca tccatcactt ctatcggaat
     6181 acccacgtga tccaacgcaa gttcatgttt tgtttctcgc gacacacgac gaaacatttt
     6241 gctggatgcc catttttcta atgctgttcc attccctttg acaccgattt ttgtggcaat
     6301 tggcaatcgt aaaacttcac tataagtcgg tgcagttcca acagaatctg gcgttgccat
     6361 catcgcaatt aaaatgtcgt ccaatccttc aaaataaaaa gtatcttgtt ttcccaatta
     6421 aaatcaccct tcccataaat caagtatttt tctagtcata atttcttcaa ttttttcttt
     6481 gttttgttca tacgtaccac ttgcaaaatg ttgggcacgt tgatttgttg tgccattttc
     6541 ggcaaagcgc cagtaaaagg ccgtctcttc aaattgaact ttcacttgat cgttttcaac
     6601 tactactttt atttgatcgc gcatatgttt cttttttaag agcgacttag gaatattagg
     6661 aagcaactgc tttagataaa agttagctgc ttcttctaaa gattccaacg ataatttttt
     6721 cggatcaact tttgaaaggt ttcctaaata atccgatatt tcagaaaaac cattcttatt
     6781 acttggcatt ttccacacac ctcacatatg tgtaatagtt ggttacggta tcgtcgttct
     6841 catcaccttg tatacctgta aaatctgaat atggaatgcc agcattttgc agcgcttgtt
     6901 caataacaac taaatcctgt tctgttccaa gtgtaaaaaa agagacttgg taataaggta
     6961 attttttata gactttaccg gatgccattt ttttgctgtt actcacattt gagtacacaa
     7021 tgtatggata catcgtccct aatctggctt tgtctctgaa cactgctaac tttgttgatt
     7081 tcagcgctgt tttcaattca tcaaagctaa tcgacataag ctaaactcaa ctccatttct
     7141 cttgcatcgg gattcgtata aatgcgagta atgttatacg ttacagaatc aattttgagc
     7201 gcacttaatt tctctgtgat ggatttatcc catctgactt taattcgtct gacaacgtct
     7261 gtcttggctt gctgtgataa atatttttct tgagaagtca caccgagttc ttcatagaat
     7321 attagacgct taaattcgta aattgtagtt ggacgatcgt ttccgtctgt tcctgttttg
     7381 atgtctagca attcggcttt ccatctgaga ttattagtct gtctcttcgg cattttgaat
     7441 cgctccttgc acgataaatg gcgtcatggc attcatagct ttgtcgagtt catcctctga
     7501 aactctatat tcataggcaa tgccggcaac catcaaaata agatattctt gttggccacc
     7561 agttgctgtt ttgacataat cttttgccat atttaaataa aaagagagca aagaatcatc
     7621 catgccctct tcaaaatgaa tatgtgattt gaatttttcc tctaaagaca attctttagt
     7681 ttgctcttcc atcttaacca ccaactggtt ttgtaatttc gtagcgatat actgccggtt
     7741 caaatggaga ataaaccaat tgaccatcta gcaagttgta aatttggaat ccaatttgat
     7801 ttttaccaga gaatttttca acaagttttt gaatttccaa ggcaccaata acttcttgaa
     7861 ttttaaatgc agaaaaatcg ccaaaatata aaactggcgt gtctggttca ccctttttat
     7921 ctgctgcatc tgtccaatcc acaggatagc caactaattg gtaaccaatt ccaccttctg
     7981 cttgtgtgaa tggccgcaac aaaggaaatc catcatctgt tttcattttt tcaatggcag
     8041 tcaaagcagc tcgattaata ataaagcgtc cctttttcat cacttctgtc actggtgtat
     8101 ttttaaattc gattaatgca tcatataatt tttgcccagc acctgaagca gttagatcta
     8161 aaggtttttt aaatgctaca gcctttttgg ctaatgcacc aggattttca tttccagcgt
     8221 catcaccatt gaacatataa ttgatttctt tacgcacata agcttttttc aattcttcca
     8281 caacaatatc ttcaactgga acaccagaca tttttaataa ttttttagtt actgttgcca
     8341 aagcatcgaa ttcggcagga ttaagcaaaa tttcatcaaa ctgaatagct gtttcagcaa
     8401 tatcagttga acgctctttc ttgtttacat tcgcatctgc tttcttcaca agaattggat
     8461 atttgacatc tcctgatgtt cgcaccactg ttccgtattt acgaagtaaa ttttcttctt
     8521 gagcataagt aataacttca gatgcaatta cttctgggac agtaactgaa ccgttgccag
     8581 cttcaatccc taaagctcga gcttctgctt cagaaatatt tccagctaca aaattagcaa
     8641 atgcttttcg tagttgttga tctttttgtt tcttggtcat ttttgcacgt gcctccaatc
     8701 cgttcttaat tgatccaagt aatccatctc gttgctgttg agtaatcatt ccagaacgat
     8761 tttctgaact atcttcactg tctgaatctt cttcttgatc gttgtcttca ccagaacggc
     8821 tttcgtctga atccgtacta ttcgattgat catctgtatt gtcgtctgtt tcatcagttc
     8881 cagaatctgc gcctaattcg tctttaattc cgttcaattc atcaataaca ctgtcaattt
     8941 cttctttcac ggcttctaaa tctgcttcgc gtaattctcc tgattcaact ttttcacgta
     9001 attcagtcaa tcgttgctca cgacgtgcct tcattttttt caataattct ttatccatgt
     9061 atttttcctc ctacgcttct agcgcttgat taattttttt gattaatttt tttctttctt
     9121 cgacgttttt ttctaattca tcacgacttc ttaatgcagc ttctgtatct tcgtatgctg
     9181 gcaaaggcac aatagaaacc tcgtataatt ccacttcatg gattgttcga agcattggtt
     9241 cagaattgta gtcccacgtt tcttcagtcg gcacaaaacc aaaactacat tggttgatgt
     9301 ctcctcgttc catagattta actaagtccc ttgctaccgt tgtgtccggt aaatcaactt
     9361 cgaatttcaa accacgttca tcttcttcaa ggcgaagggt tccgctttta gtacgtccta
     9421 gcacattgga ccaatcgtga ttgaacaaac aacgaacatc cgaattacta attgcctttg
     9481 agaatgcacc aggaacaatc acttcgctta agtcatccca taaaagtgtt tgactgttga
     9541 atacagcagc gtagccgcta atggtcctcg tatgagtttc ttcatcggaa cgtgttgaaa
     9601 gattggtgat gtcaatcgtg cgaatttcct tcttcttcat ttccatcacc tcctttcaag
     9661 tcttgatcat tcgttggtaa ggaatcatct gttgcatttt tctggccaat cctagataag
     9721 tcatttgaaa tatagatagc ttgtgtttct ggagtattct gtttaggaaa accaagcatt
     9781 tctgccacgt tatctggact tgtaatcccg gtacgaacga tgttgtagcc aatatttgtt
     9841 tttgttgagt aaggaacaaa atccaaaata ttaattttcc attccactct atagccagaa
     9901 ttaggcataa aaaaaagagc ggtgtaatgt tcgctcttgt ttttcaatat tggtttgatt
     9961 gctttgttgt gcagatacat catcgctttt tcaatatctg tcttcatcag cgattgatac
    10021 gtatcaacat tgattcctag aaattttcct aagtcttttt tgtaaacacc taaataattc
    10081 aaaattgccg cgtcatcaac aggacttttt aatgtctcga tggaatatcc ttttcccaaa
    10141 ggaatcatct taacagaatg atcactctca ttttgcgttc cttccagttg atccaatata
    10201 gctttgacaa tttttgtttg ggcgctatta tttggattga tgtgggcgtc tagtttaagc
    10261 atgaacgcaa gtaaaccgcc tttagtatat ttgtccgtca aaactttttc agcgctcaga
    10321 acgccttcta gagtgtttct tgcaagatca attattccag caccttttaa tgaatcagtt
    10381 ccgatgttct taatgtgtcg aatcatttga ccaggtattt tttgaccatt catttcaaat
    10441 tcttcttgaa gtcgttcatt gattttagtt gttacaccgt acgccaaatg aagctgatcc
    10501 ctatccgtta atgggaatgt ctcaccattg atcaataaag tatttgtttc caatttggta
    10561 aattcgaatc ctgtcaaata atcattggga ctcttcaaaa tatttagtaa gtgatgatct
    10621 ttgacttcgt tgccgtcggg accaataaca attggtgtgg ccaatgccac ctgattagat
    10681 atgtcttgaa ctaattcata aacatcagaa gattccatga tagatgaatc cgtcacatat
    10741 ctttgaccat aacgtgtgta gtgtccaaaa atatcctcga tatatccacg tttttccata
    10801 aaagaataga ctgcattcga taaccgatca cgtaatttca atttttttca ccgcctttct
    10861 atttatctat agatggaact taggtaatca tctaactcat ctgaatcaat atctgtcatt
    10921 tgattcatcg tttccttatg accacacaaa aacgccacga acccatcaat ctttttcttt
    10981 gattgacgtt tacttggcgc tttttgtcca ttgatgttag taattgctac aacgttcaaa
    11041 gtgcaataaa ggaataatgg attatcaaat tgaattcgtt tctcataaaa caaccgttcg
    11101 acatcgtcaa aaggagcatt caatacttta ggatattgag caacttcaac gcattccaat
    11161 cctaagtttt ctaatttctc aacaagtttg tcactcatcg ctggatcata attcacttgc
    11221 tgaatatcat ataaattcat gcagtcctct atgtactgca aaatctgatc ttgatcaatc
    11281 atttttccgt cgcaaaattc aacgaaacct tgttcagcca aatcactgta aggaacatta
    11341 tcttcttttt ctcgaaactc taaatcttca ttcggaataa aataaagttg ctttacttta
    11401 agaaccgctt taccatcttc atcccatgtt gggaagttta aagatacaca ggtcaaatct
    11461 cgtgtacgtg ataaatctaa accgatataa catggttcgc cacttaaatc accaagttct
    11521 tgtgtggtaa ctaaacatgg ctctacttga tcctgttcaa agaaattatc cgcgccgttc
    11581 acaaatacat ccaagtgttt cgttagaaat tcagctttgg aatgagctga ccgttgcgct
    11641 gttttaaatg ccgattctaa agcagataaa tcgactgata ttccccagtt aggattgcac
    11701 atttcccaga cttttctatc cgtccaatca taatttttat ttggctcata gattagaaca
    11761 aagtttgaat cattatcatc acgtttcaac acttcttttg cttcgcgata tacacgcatt
    11821 ccaacagacg acgaaccttt cccagcagtt gagatattaa acatcaatgg ctgtggtaaa
    11881 gatatctgag cagacttaaa attgtcatac tgttccattt tctcctgttt atgcaattca
    11941 tcgttcaata caaaatatgg attggatccc tcgatattat caatattctt ggtttgaaca
    12001 ataaatttat ttgagtaagc catatcttca tgaatatagt cataagtaat actagaaaca
    12061 gttccctttg gccccctaaa tattttagtt ccttcaagta ggattggatt gtttaagatt
    12121 gtaactgcaa aaggtttggc agcatattgc gcttgagcaa aatcagatgc gcaagcatag
    12181 caatcaactg ataacgcccc ttctccgtac attgcatatc ctaatgaacc gacagcaatc
    12241 aatgttttac cattcttttt tggaatctgg acataagcct cacgagtaac gcgtacaatt
    12301 tggccttttt cattttcttt aacccaacca taaatccaag aataaataaa tttttcccag
    12361 ggttctaaaa gaaacggttt tcccaccatt tctccttttg tgtgaacaat aaatgattct
    12421 acccaatcca tcatttcatt cgcgcgatct acatcaaacc aaatatcttt tctttttttc
    12481 cactgatacc agcgatctat tgctaaacga acggtcttag gatacttctt aggtttcttt
    12541 cttacttctt ttgcaaataa atcagcataa tttacaccag gttcaatcat ttttcagcac
    12601 ctgccttctt acgccattta tttctgtgcg ctgctagttc atctactggc tttacttctg
    12661 ggcgtgtaat ttcttcatct tttcttgcgg tcgatcctcc agcaattagt ctaccagttt
    12721 ttgctttgtt tgttaatcct aataaatcta gagctttcat cttcttatct gcccaagttt
    12781 ctacttgttg tgccaatgga tgttttgatt gattagtagc tcctgattta ttcgtgaatt
    12841 tttgcgtctc cggaaatcct ttttccttcc acaataaata tttgtgttgg taaatttcaa
    12901 aaatatccaa gtatgattcg attaatggat caagagtgat ggtgtacaaa tcagacaaat
    12961 tcattatttc taagatacga gctttttcag cacttacttt ttcatcaata atcgctttac
    13021 gttgcgcttt agtcgtcatt tttgtataca cccccctttg ttttttgaaa aatttgacct
    13081 aacgatgcgc gtgactcccc gctaccctat ctccccacgc gaaaaaattt tgaaaatgaa
    13141 taggggggct tcaattgaaa tacgaaggaa aaactttttt gtcttccgtt tcgttttcaa
    13201 caattggatg acattttgaa cataatagca tgagattgtt tggatcaagc ttaagcagtt
    13261 cgttgtcttt gattggtaca atgtgatgga cgtgtgctct ctttccaaat atgaactgac
    13321 cacaccgctg acaatgacca ccttctcttt cataaataaa ttgacgcata tctttccatg
    13381 cttgcgttcg atagaatggt ttgttctcat gatgataaac agactttgct tgctgcttct
    13441 tcttgcgtga tctgcttgat ctcttgtgtt cagtacagta gatacccttt gctattttgt
    13501 tcgtgcatcc gtcaaactga cagtatttca ttctacttca cgaataagat ttatgatatc
    13561 gccttttgca cggatagcac caggaatatc aataccatgt ttcttagcat atgcacgcaa
    13621 ttcttttgca gtcatattgt ccagttcatc cgtatcttca gtggactgat cattagtagc
    13681 ttcgtctcca tcaaaattag cagcagtgtt tccatcgcta tcaagaattt cactgctatg
    13741 agctatgagt tcgccattga cagcaacaaa tgatttgcca tcactcaaaa ttcctttttc
    13801 ttcttttact tcaaaatttg gttcttgatc tttcggaaca actactgtcc ttttcttttc
    13861 tgaatcccaa tactctgttc cactaatgga tgttctaatt ttgatcattg ccattttaat
    13921 tctctccttt gtaatttgta cggattactt ttgcgcccat tcgctcatac cattcaatcg
    13981 tttcctgcag attgggtaga gtgtgtgaca ataaagaaat aactaacgta ttcattccag
    14041 ttctgtaatc atcattctcc acttgcacat gtgcatgatt accattccaa ttttctctgt
    14101 acggactatt ctctgcttca attgctttct tataaacttt agccaaactt gattctactt
    14161 caatactaag taccgcttca tgaaaatcat tcatttgttt actctcctat cagatatttt
    14221 gtggtatgat ttataaaaaa gatgcgaggt gttttaatgc ttcaagaagt taatattaag
    14281 tatcgtgatc gtcaaaatac agagacaatt tatttgccaa atagttgtcc gcattgcgga
    14341 aatataatga ctccgtatgt gtattttggg gtttcatcat atagtgcgtt cgataatgat
    14401 agaatctttg gcgtattagt acagtgtata aatgatgagt gcaacaaatt ttatagttta
    14461 caatttataa atacgtttaa tgaagatgaa ggatattctg aaaatatttt aattaaagat
    14521 tattaccgtc cgccgattaa aatagattta ccagaaaata ttgaaaaagt ttctcctaca
    14581 tttgttgata tttatactca agccacacaa gctaaatctg agcaattgga acaaattgct
    14641 ggagttggtt atagaaaagc tctagaattt ctaattaaag attatgcaat atctaaaaat
    14701 tcagaggatg aagataaaat aaaaaaaatg ttattaggta aaacaattga aaattatttg
    14761 aatgattttc ctaaactcca aagattagcc aaagctgcta cttggattgg taatgatgaa
    14821 acgcactatg ttcgtagaca tactaataaa gatgttcatg atatggatgc atttattaaa
    14881 tcagcagcgc aatttatcgc ggctgattat gatgctgatt tagctgatca atttataaat
    14941 ggaaataact ttatgccaac tactaattaa aagaataaaa gagccacaga taccaattaa
    15001 taaaacggtt gggatatctt ggctctttca tatttttttg acactaatag aatatcatgc
    15061 tgctaacaat gtttacatag ctacaatgac cgaacattta gtgaacagtg taattttaga
    15121 ataaagagag ttgttctttg tacttctcgc tattgtaaaa atcaatttcg ttttcttttt
    15181 tcaatcggtc agcttgtctg tgttcatact catctaaaaa gttcaatgtc tttctaattt
    15241 ctgcatgtcg ctgtctgaca tacgatgagc tatacccaac agattcagca atatcttcta
    15301 agctcatttg atcaacatat ttcatcttaa caatttgatt atcgatacca gaaaagctat
    15361 ctatcagcaa taacatttct tctttttgct cgatcaacaa ttccaattca ttttctatct
    15421 tttggatatt ctcttctaaa gaagaagttc tcgaattctt ttcgatgcgg acgtttgcta
    15481 aatcaccaca gacccatcga ttcaattcaa gcttactttt attaagattc cactttaagt
    15541 aaagaatctg ctcatctagt tcttggtaat cttttaacca atgaaatctc acaaacgcca
    15601 ccccttatgg tagaatagta ttgcgctgct atctcgaaag gggtagcttt tttatttttt
    15661 cttagccgtt ccattctgga ttgccttttg ttccaaacgt cgttttttct tcttaatctt
    15721 tgattttgtt tttcccatac aattctcctt tccgaaaaca cattttgttc gatttttaat
    15781 actaaataaa agttggccag aatttttcgt tcgtctttac tcatcttttt ttgaataaga
    15841 ttactagcat aaaaatagtt agtaccacga aaatgaacag gtaaatcaat tacgttcacc
    15901 ttcttcatgc cagttatcag ccactagaat ctttgcgtta gtgccgccac cgttttcttt
    15961 tttgtatttt tcaaatgctt tataagcagc tgtttttgat ttatagattt ttccggaacc
    16021 gactgggaac atccatgtgc cctctgtgat agctaagatg tatactttca tttaattcac
    16081 ccctttaatc cccaacacta catatccgga cttctgcatg taatcagtaa tataagtgat
    16141 ctctgctttg tatgagtcac cagtgtaact aaatgttggt ctcgttagtc caggtaattc
    16201 atgtttaatg tattttttat attcacgtag tattaactga tcaccaactt tgaagtcacg
    16261 atcattcttg cggatctcga attgtttgcg tccgctcgtc actgcttcaa aatattctgg
    16321 tagtattttt agttcgtgga tcattctgtt tcctccttca aaattcgctc atcatcaaaa
    16381 agtgaatctc cacaaaatcc ttctcccaaa tatttatcgt tcatgtataa gtcaaccaaa
    16441 tatttgtgat ctgcttctcg atattcatta atattaacga tctttatttt gtaaacatta
    16501 ccttcgtcgc tcactatctt gaattgttct ctgactttca ccaccgttcc tcctcttttt
    16561 gaaaaaattt tagtgttttt gtaagacccc ctaaatcagc ttttttattt gatataatac
    16621 ttgtatcgat taatcaaatc gaaattaaat ttaaaaaggt gatttatcat gaatatcaac
    16681 aatttagtaa aactcgttga acaacgtttt aaagaatcag gattagaaca attaaaaaaa
    16741 gataattctc cagaattatt ttctaatttt accgaagacg acattcctac tcttaaacaa
    16801 ttaaaatatt attctgatta ttggacgcaa actcgtgaga atgaattaaa tttagaaaaa
    16861 ctcattatta aaaagaaata gcaactccag cccacacggc tggtttttta gtttcaactt
    16921 ccctccttac gggtcaaaat catcggttcc ggcataatct gatcatcctt tagcaacaaa
    16981 tcaggatatt ttttccttag cttcttattg ttcgtgtaag ttttcaatag ccattggttg
    17041 gcttcgcttt tgctttctcc agaaaaataa attttccctg tttggatgcc tgcaagttga
    17101 atcatcattt tcacctcaaa tcaaattttt tctgctagat ggagcaaaag caatccgaca
    17161 tcaagaatct tttgacccat tatttcagct actttgctcg gcttaactcc ttgagaaaag
    17221 agcaagcgtg cttgctctat ctcttcgtga gtccaaataa atttggcttc ctcaaggata
    17281 attactggat cagttgctct cattgttcct ctggaaaaat gatgtcattc ttatgcttgg
    17341 accaggtatc tgcatatgga acaaagtatt gtctagctaa ttcgatttga tcaattaaag
    17401 cagtttctga taattcatgg tctgcagcaa tttcattcat actatcgcct tcatctaaac
    17461 agataagacc gttgacgtta tcgattttta catttgtgac tgcttgactt tctccacgct
    17521 cataatattc tacagttgat actgatacat cagcttcgga gtttaattgc agaatctgtt
    17581 actgccggga taatttaata ttcttttcat aattcacctt ttttcctact gacatcgaat
    17641 atttttcatg ttatgattag ccgtgaaagg agagctatat tatgtgttta cacatgatgt
    17701 ccttagctca ttcggttctt tggaagcttt tttggaaata actctcaggt tcttgacgca
    17761 aatctcattt attctttgaa acaaaaaact tccattttcc gagagctttg gatcacttca
    17821 aaagagattt gcatttatat ttctgtgacc ttgagtcgcg taaagaacct tacagcaatg
    17881 gcggcaattc cactttcagg aaaccgcctt ttttcattga tattggtggt tagcggacta
    17941 cccattttct ttcggcagtg ccaaaccaca aatgatctgt gttgatgttt aggtagttgt
    18001 ataccagata agctaaatcc aaagtgcctg catcttcaag acgacaatat tccaaaaatt
    18061 ctcccatagc tggacataaa aatcctggag ctatcatatc ccaacagtta atagtgcaaa
    18121 gaaattcgtt tagcttctga acgttttctt tggtttcacg aattacaaca tactccaatt
    18181 cttctccgct ggcagagcat tccaaaactt caaattgatt aagaaatggt agaacatatg
    18241 cttcaaacat caacattcca tctttctgtt tttgcacttg ttttgcatca atcatgtcta
    18301 tcctcctatt cagttatttc ttccattaat ggaattattt caggtcactg gacttaacga
    18361 aaacaccatt gaccatcttt ccagtccgac ctttgatttc gtcataagca aaatccaagc
    18421 actcgtataa atccatatca ttttgcattg ccaagatgat caaggttact actacatcgc
    18481 caattccgtc tcttaaacca tgttcatctt ttctagctag agaagcggca acttccccga
    18541 tttcttcgac cgtttttaac atttgcttgc tgaaatccgc ttgatccaat cccttatctt
    18601 ttgcccactg ctctactttc gcgattagtt cgtccattat ttctcctcca catacctaaa
    18661 ctgtcttcct tttgaatcaa tccataagct cctagctcta tcccaaataa tatttttgct
    18721 cagaccagta atttcagata actgtttagc ggtacccgtt actagaattc gatcaccatg
    18781 ccagattgca atctttctcg gcgttctccg tttgggcttt tcagtccaca ttgatttacc
    18841 gagcttttgg acttctgcaa ctattttttt atcttcctgc caatcttctg aataagtcaa
    18901 ttcgataatt cgctgcattg ccgctttctt atccatcccg acattctcct ttcagtaatt
    18961 tgagtacttg atcaagtgcg ctctcacgtc cgccatgaaa tgtgttgagc cacttgtctt
    19021 cgtacgacac actttgtctt aaagcttctt gatgcattaa ttcgatctgt gctgtaaatg
    19081 tctttaggtc catcttgttt acacctgctc aagttcatta agatgttttt gcaagccttt
    19141 aacacaatca atgaatagta atttggtata tgctaaattt cttaattgcg ttccatcgat
    19201 atagagtgcg aaatagtatc tgag
//
LOCUS       DADGKS010000055        18714 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.055, whole genome shotgun sequence.
ACCESSION   DADGKS010000055 DADGKS010000000
VERSION     DADGKS010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18714
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.055"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            275..1753
                     /locus_tag="JXV47_002040"
     CDS             275..1753
                     /locus_tag="JXV47_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAX1488064.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            2030..4089
                     /locus_tag="JXV47_002041"
                     /pseudo
     CDS             2030..4089
                     /locus_tag="JXV47_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4172..4741
                     /locus_tag="JXV47_002042"
     CDS             4172..4741
                     /locus_tag="JXV47_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1488065.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(4916..5722)
                     /locus_tag="JXV47_002043"
     CDS             complement(4916..5722)
                     /locus_tag="JXV47_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488066.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            5860..7374
                     /locus_tag="JXV47_002044"
     CDS             5860..7374
                     /locus_tag="JXV47_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HAX1488067.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(7777..8760)
                     /locus_tag="JXV47_002045"
     CDS             complement(7777..8760)
                     /locus_tag="JXV47_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HAX1488068.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(8765..9412)
                     /locus_tag="JXV47_002046"
     CDS             complement(8765..9412)
                     /locus_tag="JXV47_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAX1488069.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(9497..10129)
                     /locus_tag="JXV47_002047"
     CDS             complement(9497..10129)
                     /locus_tag="JXV47_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAX1488070.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(10145..10696)
                     /gene="coaC"
                     /locus_tag="JXV47_002048"
     CDS             complement(10145..10696)
                     /gene="coaC"
                     /locus_tag="JXV47_002048"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HAX1488071.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(10693..11430)
                     /locus_tag="JXV47_002049"
     CDS             complement(10693..11430)
                     /locus_tag="JXV47_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HAX1488072.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(11427..12416)
                     /locus_tag="JXV47_002050"
     CDS             complement(11427..12416)
                     /locus_tag="JXV47_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HAX1488073.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIITFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            12674..13216
                     /locus_tag="JXV47_002051"
     CDS             12674..13216
                     /locus_tag="JXV47_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1488074.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            13233..14318
                     /locus_tag="JXV47_002052"
     CDS             13233..14318
                     /locus_tag="JXV47_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1488075.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            14330..15136
                     /locus_tag="JXV47_002053"
     CDS             14330..15136
                     /locus_tag="JXV47_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1488076.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            15137..15964
                     /locus_tag="JXV47_002054"
     CDS             15137..15964
                     /locus_tag="JXV47_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1488077.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            15961..17034
                     /locus_tag="JXV47_002055"
     CDS             15961..17034
                     /locus_tag="JXV47_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAX1488078.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            17462..>18714
                     /locus_tag="JXV47_002056"
     CDS             17462..>18714
                     /locus_tag="JXV47_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAX1488079.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNE"
BASE COUNT         6141 a         3257 c         3756 g         5560 t
ORIGIN      
        1 taaaagagca ggacggtggc cgtcctgctc ttttttgtgg ttgtttacgc aaatggcgca
       61 aatcttgtac attttaacac aataaaacaa aaaatataga atatttcctc ataaattttt
      121 ccattttttg caatattctc aaaaaaaaga taaaaaatga gaataactga tgaaaaaaca
      181 agcataatcc atcataaaat cagtataggt gaaaagatga actttcatct gcatatcaag
      241 taattggtat gaggcatttt ttgaggtgta ggatatgaag ttggattacc ttatagaaga
      301 ggaagataga gaaaaactgc tgctagctag atatttagaa tttgagaaaa agaattatgt
      361 agtgctgcct aagttatatg aaacattagg tttgtctaaa tttaaaacaa gaaattatat
      421 catagaatta aataaagaat ttactgaatt caaaacaaag ccagagatcc aaatttcaga
      481 agaagcagag atccatgtcg aacgtctgaa tttgacggat atcaaaaatt taagaagaat
      541 ctactttcaa cgatcaaaaa ttgctcgact gttaacggag atcgtggatt caaaagtaac
      601 gatcgaaaaa tttgcagaga atcatttttt aagcatatca agagcctatg taaaaagaag
      661 agaattagtc tcttttcttg aacagcatca aataaagtta aagaaaaaca tattagttgg
      721 ggaagaaata aacatacgga acgtattatt tggggtatat ttcggggtct ttaatggttt
      781 ttctatgcca tttagagaaa gcgtcatgaa tgaagcaaag agtatcgtgc aatattttga
      841 atatctgttc aatttaaaac tgtctgcaac aaaacgaatc aaattcaatt tgctaaccac
      901 tattagtttg ttgagggcct atgggaatca accaatcgga aaacgtttct tttcagatga
      961 atactttaag agctcagaag gaatgaagat catcaaggat ttatcacata tttcttttct
     1021 tcatatccct aaagagcaga tcattgatga gatttcttat atcatgttgt ttttgatcac
     1081 ggaagaagaa tttgaattag atggcgcatt tggacttgcg gaagctcatt ttcatgatat
     1141 ccacatgatt agtcaaaaaa tgtcagtgga attgattgat caattaccat tttcgattga
     1201 aatctctgaa gaagaaagac tatatatacg aaaagaactt cgtatgggta tgatgcatgt
     1261 caatcgaaaa aattggatat tcgactttga gatgactagc tttacgtcta aaaagcagct
     1321 acagtttttc ttcgagacgt atccaatatt cagtacagca atccaaaagg tcatacaaga
     1381 gaataaacgc tatttcttgg gaaaagatga acgtttcatg attcgcttat tttatgatta
     1441 tctcttttta ttggtcggta tttgtccggt atcatatttt gaagcaccga ttcatgtctg
     1501 tattgatttt tcgcaaggat ctgcttatac cgattacatt atttctcaag tgaaaggatt
     1561 taaaaattac aatattgtga ttgagagtcg aatcacttct cgtacgaata tttatttatc
     1621 tgattgttta cttgaaaaat ttaataaaga acagataatt tggaaaaatc caccgactcc
     1681 agatgactgg gaatattttg gaaataccat catcagagaa aaaaatagac atttaactga
     1741 aaaaatcagc tagtatttat ggatggcagc tttgtctcac atatttatta gctgatttat
     1801 gtttttttca aagaaaaggt aactagatat aactagatat aactagatat attacttaac
     1861 aaaattaaaa agtacataag ttattattcc gattttcttg aaacaataaa aaatcaaaaa
     1921 aaatactctc ctaatagtcc atcttctttt gattttattt atataatgaa atcatcttat
     1981 gaaaattact acttcatgtt tagacaagag tagggaggac taagaataaa tgtgttcaaa
     2041 aagacgttca aaacaactaa ataaacacgc ttgtcgttta gataaggaac ggtcgtgttc
     2101 tgaaaaacac tacgttaagt ttatgatgcg cacgatgctg atcagtttat ctgtaggtgt
     2161 ctatatgcat gtacccgttc aggcaacgac acaaaccatc aaggtcgtac gtacctctgt
     2221 ttctgagacc actgattccc ctatcactat tactcatact ttcactgatg caaatggaaa
     2281 acagctactt cctgcattga cttcctataa taaagtcagt tatcctccaa cgataaacca
     2341 ctactggtta attcctaaca aaacattatg gacatcggaa accggaagca gtgtgccgct
     2401 ttctatcttt tccgatatga ctgatcctac aaaaggtgat cagttaaaac agatcactga
     2461 tattttgaat catgctttga cagatataaa ggacggtgga agcgcacaag tttcttatgt
     2521 atatgaaaaa gattattcac agtttgaaag aaagaaaatc gatgttctgg cagggacaaa
     2581 agtttcgata tctgatctgg tagaaaggct gaagaacgca gatggaacac aaggagatat
     2641 gtccaaagta atttcaaaca atgggaatat cgtggatacg actaatacag gaacatctac
     2701 tatttccttg tcctattttg atccaattgc tttaaaaaca atgactgcat ctgctgtgat
     2761 ccatgttcgt gctgatcaaa cagctatcaa aggaaaagat cttcacttaa gaacaggaga
     2821 gagttacgcc cctaaagatc ttgttgaata tgtaacaaaa agcgatggaa cttcaggaaa
     2881 taaagaagaa atcaaaatga acgggacagt agatactaca actccgggag aatatcccgt
     2941 tgtattaact tatatagact cgaaaacatc aaatgtggca gaaacaacag ctgtagttta
     3001 tgtagaagca tctgctgctt catcgactgt catcactcat tttatagata gtcaaacaaa
     3061 taaagaactt caagcagaaa cacatatgag tagtgtaaat cgtattcctg atttgcgcct
     3121 acctgctgaa ttttctgatc gagtgccaaa tatagattta tcgacttatg aacaaaatgg
     3181 gaaagtcact tctatttctg attggatgca agcaaacgga ttagacagaa aaagtcactg
     3241 gtcggagatc cttgaagtac ttcactcaga actgatgaat aataggaagc aatcaggagg
     3301 ggaaattacc tttacttatg tttatatacc agacaatcgt tcattagaag gtcatgatct
     3361 tattgttcat ccaaacgaaa aaataaacaa agaagagttg atccaatcag caacaaattc
     3421 cttaggtaaa cccgtaccgt taaaggatgt atcggttaca atcaatgaag taccattgga
     3481 ggatggttat ttgaccaaac aaacaggtga ttttacgatt atgtatagtt atcatgaccc
     3541 gtattcactc caagaactcc atgctcagtc actattacat gttttaccat taaacaaaca
     3601 gatagatcaa aaagaacaaa aaagacaaga agaaagcttg tcagaaaaaa acaacaaatg
     3661 gctcatgcag tttctccaac agggaaagta aaacaaacaa gaagcctaga gttagcaaga
     3721 atatctagaa aaatctcaga atctaataaa acgataaggc aagaagctca tttggcccca
     3781 caagtttctg gattggaaaa tgaaatttta gagcctaaaa taaaacaaca atcagaaaaa
     3841 gaatttgttg ctaaacagtc ggaagatcag aaggaatcag atgaccagaa ggaaacgaag
     3901 aaaaaacgct tgtcaactat tgattccacc gatgagcatc tgcagccgca agtaccactt
     3961 cctagtccgg gaacacccgc acctggtgga ggtattcctt cttctgcttt aggagatttc
     4021 atgcgaggta tggcaggaac atgggtatac gctaatcgaa atgaatttga cgcagatgac
     4081 tggttctgat ttatatctct atctgttata gtcaaataag tagctgagtc atatgttatt
     4141 tggcataatg gagacgagga gggatagaaa aatgttagat aaaacgttac cttacgcaga
     4201 aatctggatg acaagaccac ttcaacaaaa tgttccaatc acgcctttag cggaaggttt
     4261 tgaatttcga ttttatcaaa aagaagatga atctgcttgg gcggagattg agacttccgt
     4321 tggggaattt caaacgacag atgaagcact tgagtatttt caacaaaact ttgctcctta
     4381 tcctgaagaa cttgaaagaa ggatgttttt tgtagagaca aaaaaaggag aaaaagtagc
     4441 aacctgtacc gcttggcgaa aaaaatcaag agagcaagtg tatccggttt ttcattggtt
     4501 agcagtgaaa ccagattacc aaggaaaagg gctcgcaaaa gcattgactg ccagagtctt
     4561 gcaagaattt cctaccctcc atacggacgg accaatctat cttcacacac agacatggag
     4621 ccatcaggcg attgctcttt ataaaaaaat gggttttact tttattgctg aaaatctaga
     4681 cggcacacct aatccagatt atgaaaaagt tatgcaggtt ttaagtaaat tagataaata
     4741 acgaaatggt gaaataagtc ctcagtattg ggataaaaaa cgaaatagtc attcctcata
     4801 tcttactttt ttgagttaat actatcggat aactaatggc atgccataca ttcaaaaaag
     4861 aaggggcagt gacaaaagta ttgtcactgc cccttctctt gttttttagc atgttttatc
     4921 gtttgatttt tttaggaata aaattcttga tgaacgtaaa tttttggtaa tcgtttcgac
     4981 tatagaggta accaaataca ctgaaaacaa ctgctccaat aaaattaaca aataaatcct
     5041 tcatagtatc catgattccc acgtctaagt aaccattttg gatgattgtt ttatctgttt
     5101 taccatctgc attttgactt tcaatgattg tccgagtgat atctggaaca tgatagacag
     5161 tgtttccgtc tttacttaac tccacactat tgatttgctg gatgatcgta tctttttgca
     5221 tatcgaattg cagtaattta tctgctgaaa attccacaaa ctcccacata acaccaactg
     5281 tcatcgaaaa acagaaggaa acaactgcta gtaataaagg agtcaagttc atggtttttg
     5341 tatttttatt gagcaaataa acaagggaaa agccgacacc cccagctaaa aatccgctga
     5401 atgcatgtag aaaagtatcc cacattgaaa aatagccata aaaatcactt aactctccta
     5461 aaactgttga actaaaaata aaagataaca aaatgatttc tagcatattt ggaatctgta
     5521 tctttaatat cttttccaga aaataaggga tttcaaataa aattaatgtc agtaataaaa
     5581 gcattgtatt tccccagtgt tggttccaga cctgatccac tagcataata acgacgatga
     5641 tacgtaataa aatatagatt ccgtttgtga ttctacctgc agtttttgta ctgttcgtaa
     5701 aaaaggtttt caaatgattc ataaaataac tccttcatgt atatccttaa ttatactaag
     5761 aagcgtgtgt ttaccaaagc tatatgactt aaagaaaaac agagttgata ttgtgaaaaa
     5821 aatcacttaa tatagtataa ggagaaaagg gggatacaaa tgaaaaaatt agttgctggt
     5881 ttattaacag ccgttgcact tcttgctatg agcgcatgcg gcgcagatca gaaaaataca
     5941 gcgcagacaa gttctagtac gaaggaatct gccgaagtat catcaggcgc ttctgaacaa
     6001 gtatatacag atccaaaaga aatgaaagaa tcttatgatg tcgtgattat tggagctggt
     6061 ggtgcaggga tggcagcagc tatcgaagca aaagatgctg ggttgaatcc agtaattttg
     6121 gaaaagatgc ctgttgccgg aggaaacaca tctaaatcat caagcggtat gaatgcttca
     6181 gaaacaaaat ttcaaaaaga agaaggaatc aaagactcga atgatgcctt ctatgaagaa
     6241 acgctaaaag gtggtggagg aacgaatgat aaagaaatgc ttcgatactt tgtcgatcac
     6301 tctgctgatg cggtcgattg gctagatcaa aacggtatca aactggacaa cttaacgatc
     6361 actggaggga tgagtgaaaa gaggacacat cgtccgtctg atggctcggc tattggtgga
     6421 tacttagtgg aggggttatt gaataacgtc catgagcggg aaatccctat ttttgtcaac
     6481 gcagatgtga cagacattaa gaaaaatggg gaaacggtca atgaagtgac tgtacatgtt
     6541 caaggagaag aaccaaaaga ggtcaccgga aaagcaatcg tagttaccac aggcggtttt
     6601 ggtgccagca aagaatttat tgaaaaatat cgtcccgatt tagctgatta tattacgaca
     6661 aatcaagaag gatcaactgg agatggtatc accatgattg aaaaattagg tggacaaacc
     6721 gttgatatgg ataaaataca aattcatcca actgtgcagc aggatgaggg ggtcttgatt
     6781 ggtgaggttg ttcgcggaga aggagcaatc ttggtcgatc aagaggggaa aagatttgtc
     6841 aatgaaatgg atacaaggga taaagtatct gcagcaatta cagcattgcc tgaaaaatca
     6901 gcttatttga tttttgacca aggcgtgcgt gatcgtgcca cagctattga attttatgac
     6961 caaaaaggat atgtcacaac tggaaagaca atggaagaat tagcagaaaa aatcgattta
     7021 ccaaaagaaa cactagcaaa aacagttgat ggatggaata cggatgttgc ggagaaaaaa
     7081 gatgctcaat tcaaccgtgc cacagccatg gaacatgact tatcgtctcc gaattattat
     7141 gcgatcaaaa tcgcaccagg aatccattac acgatgggcg gtgtgaaaat caatacgaac
     7201 actgaagtat tagataaaga aaaccagcca attagggggt tatatgctgc tggtgaagtc
     7261 acaggtggct tacatggaaa caaccggatc ggtggaaatt cagttgcgga gatcattatt
     7321 tttgggcgac aagcgggcat acaagcagct cgatttgctt cggaaaatga atgaaataga
     7381 acgtaaataa aaagaggttg tgaaatcagc gttttgagct aataccgagg gtcagctgat
     7441 tgaacactgt ttagtgaaga ggttgtgaaa aagctgccct gcatcaagta ataagaacag
     7501 ccaagtaaaa acagcttctt atgtttttaa cttggttgga cttattaccg cagatgcaag
     7561 cttttgaaca ccgtttattc ggaaaaagag cgtgggacaa aagtaaagaa cacttttgtc
     7621 tcacgctcta aacacgtata aacggcggaa gcagaagaaa ttccttcgga aataagctga
     7681 aattcacaaa aatttgaaaa gcaattttcg tgaatttctt cttatttctt ggagttaaac
     7741 gcttctgtcc cagcctcttt tttgatcagc atgattttat tcagttatct tcaaaatgat
     7801 ttttccgatg tttttgtttg cttccatata ttcatgcgct tgtttgactg cgctgaattg
     7861 gaatgtacgg tcaatgattg gccgaatctt gccattttct agaaaaggcc cagctttttg
     7921 cataaaagtt tgtgcgagct ctgctttata ctgatcactt ctaggtgtca ataatgtacc
     7981 aagcagttgg acacgtttcc caatcaatac accaaggtct atctcaggca cgatggtccc
     8041 acctagcata ccaatcaaga cccaacgtcc atcaacggct atagaagcta aattcttttc
     8101 ccagtaagaa gcgccgatga aatccaaaat aacatcgact ccccgacctt cagtgatttt
     8161 tcgtacctct tcttgaaagt cttgtttttt atagttgatc aattcatctg caccaagttc
     8221 tttacaaaag gcgagttttt cttctgatcc tgcagtaacg atgattttcg cgtgagaaag
     8281 ctgtctagct aattggatcg ctgctgttcc cacaccactt gctcctgcat ggatcaagac
     8341 agtttcgcct tcttgtaatt ttccaagcca gtaaagtgtt tgataagcag tcaaaaaaac
     8401 ttctgagatt ccagcagcag aaacatagtc tagcgtatca gggagaagga ttgcacgatc
     8461 ggcaggcatc acagcatatt cggcataacc acctagattg actaatccgt atacttttgt
     8521 cccaggagta aaagtggaga tatcactttt attctcaact acctctccag ctacttcgac
     8581 tcccaaaata gggtagggag gtttcaaaga gactgattct cttttcataa tatctgttcg
     8641 attgacagct gctgtatgga ctttgatcag taattcgcct tgttttggtt taggaacagg
     8701 cacttcaatt tgttctaata catctacaga accaggatgc ttgattgaaa tggcacgcat
     8761 ggatctattc ctcctttgcc cattcttgga atgctgtatt caactctttg ctaccttcag
     8821 aaagtactag agtcgtacga gaaatatccg tttcttccac tagagcggca agtacagcag
     8881 caactgtaga gcgagtgatc gtttttgatg ccttctcatt aggcttagtt aattgaatgg
     8941 aagtaacttc ttcatcgtta gtcaatgtga ctggttgaag aatgacaaaa tctaagttag
     9001 ttcgtttcag ccattcatct gcataatgtt tagtaatata ataatctgtc atggactcag
     9061 gccattttgc tggttcatct gcataaacag cactgaccat cagatagcga gagacatgcg
     9121 cattttcagc tgcgatcact gttttgattg cgccatccaa gtctacttgc agaagattct
     9181 ttccttgaga gccggcagca aaaatcaata catcgatgcc tttgaatgct tcggtcattt
     9241 tttccacgga ccaagttaaa tcaaaagaga catacgaaac attctctttt tttactaatg
     9301 tttgggaagc aacatctctc acccctgcaa aaatttcatg ggaacttgga gctaaatctt
     9361 ttatcaggtg tcggccaatt tgtccgtttg cacctacaac aaaaattttc atttggatca
     9421 tcctttcgac gtcaaatctt tccattcaat agtaacacca aaagagaaaa aaatcagaga
     9481 tcggctacga tgactatcag ttagtaagag aagggtgctt gaagtatctt aacaagacat
     9541 tgcatactgc tgcagtcgca agacctgcga cgattccttc aggtatacca cttgtaaaaa
     9601 taaccgctag aatagctgaa taaacagcat ttaaatttgt tccgatgact ttggcataat
     9661 cttgctggaa taaaaagtag atcatattca tcactaaaat cgtattggtc aatgaaccgg
     9721 aaagtccagc taagaataaa gaaacggaat ctgctttttg tttcattagt ttgcgcagac
     9781 ctttataaac gaaataagga accaccccaa tcaagatgcg aggaataaac gcgatcagca
     9841 aggctttcca gcttccatgt tctgttccga tgactgggat aaacggagaa aagacaaaag
     9901 acaaaggtgt ttggataact gtgctacgga tcatgctgat cagtccaaat gtaccgccaa
     9961 gaaaagcacc tagtcttggt cctaaaacga tcgaagcaat gattacagga atatgcatgg
    10021 ttgttgcatt gattggaccg atagggataa aacctaaagg cgtaacagct aataaaatca
    10081 aaatagctaa aaacatcgca gttaatgtaa agttttttgt atttttcata agtactcctt
    10141 ttttctaagc atttctttca ttaagagtca gcatgacctg ttcgatgatc gtctgaatat
    10201 cagctaaggc accttttcca aaatctccac aagctaaaag agattctctt ggttcaattt
    10261 cctgatagcc gacagatctc aatgtttcca gattacgctg agtgatcggg ttttgataca
    10321 tattcgtgtt catggcaggg gcaatcaatt ttggtgttcc cactggaagc gccattgcga
    10381 ctgttgaaag aagatcgtct gcaatgccgt ttgctagctt gccgataatg tttgctgtag
    10441 caggcgcgat gagaaacaag tcagcttgtt ttgctagttc gatatgattg attacctgcg
    10501 gatttgattc ttgcatgacg tctgtatgga ctgcgcgctt cgacagagat tgcaaggtta
    10561 atggcgtgat aaaatgtgtg ctgcttttag acataatcac atctacctgg gcacctaatt
    10621 tgacgaattg acttgtaaga tcagcgcttt tgtaagcaga aatacttcca gtaacgccta
    10681 gtaagatctt tttcattttg attcctccag tctaattttc tcagtaatca atgcagcaat
    10741 ctcagattta ctttgagctt cttccactgt tccatcttta gataagagat agccgtggtg
    10801 tgtctcgcca tggatttccg tcaaatcatt tgcgaaaata aaatcagttt tgttatttat
    10861 cagactattt tttgcgactg ccagaagaga ttcctttggt acatctacta atagtttgaa
    10921 accaatgatt tttgcttttg gctgccattc acgtagataa gaaatgattt ttggtgtttt
    10981 cttcaaaacg agcacaagat gctcggtgtt agaagagatc tttgaaacag tggtatctgt
    11041 ctgttcattt tccgcaaacc aattgtccag ttcttcttgc gttgaagaag tgggtaggtt
    11101 ttttgccagc tgttcttctg aaaaactaaa agcaggagta aaatcactga ctgccatact
    11161 gtggataatc gcatcgtagt gttctttttt cgttagttct tctaattgta aaaataagtc
    11221 cagtgcagat tcgatcgtat aaatcgttat attggagtgt cttttcggtt tcagtgcttg
    11281 tttcgtagtc acgtaatcga ttgtggtatc cggattggca gctaaataat cagctaatgc
    11341 ttgccctaat cgtcctgtcg aatgatttgt aatagcacgt acttgatcga ttttttcagt
    11401 cgttcctcca gctgtgatta gaatcttcat ttatggtcac ctacatttac tagtgttctt
    11461 ccttggtgtg ttccagcaag tagtttagat gctgtttcag gcaattgatc cagagtaatc
    11521 tcttggacga ccagttcatc tgcaatctgc aaatccgcca tctgttgcca taaagaaaga
    11581 cgttgatcta ttggtacatt gacagaatca attccaatca actggatgtt tcgcagaata
    11641 aaaggcaaga cagtcgcgtt tagtttgatt cccccagcat tgccacataa agctactgca
    11701 ccgttataag agatcaatgg aagaagactg cttagctgct cgccacctac tgtgtcgatg
    11761 acatagtcga tttgctgttt tcctaaagct tttgttgtct ctggcagaaa ttcatcaggt
    11821 cgtacgactt gcaaagcacc tagacttttt agccatgtga cagactcttc ttttctggaa
    11881 aaggtaatga ttgactggaa tcctagttta tgtaacaggg ctatcgctgt actgcctaca
    11941 ccgccagaag caccagtaac gacaactttt ttatcggagg tcataccttg acggattaaa
    12001 gcgttcacac acaacatagc agtaaaccct gctgtaccaa ggatcatcgc ttgacgcagc
    12061 gtcatatttt ttggtagagg aactaaccag tctcctggta ctttttgata ttggctataa
    12121 ccgcctggat gggtgacgcc aagcccaaaa ccagtagcaa gtacaagatc ttcttttgaa
    12181 aaacgtggat tgttactttg gacgacagtt ccggataaat caatccctgg agtcatcgga
    12241 tatgttcgta tcacctgacc agactcgctc attgccaatg catctttata attgacatca
    12301 gaataggcaa tttttaccaa gacttcattt tcagccaact cagtaaatgg cagatcactg
    12361 attgctgtat ggaaaacagg ttcctttatt acctgaaaag atcgaaaagc gttcattcgt
    12421 gagacactcc ttttaaaatt ttcttttatc ataccataaa gcctactctt ttattcttgt
    12481 tcttccgtaa atttagacaa aaattaggtg aaaaataaag aatcaaacaa ctagaattta
    12541 ttccaaaaga taaagaaata ttcagcaaaa aaaattttac aaagggttgc ctttttcaat
    12601 aaatttcgta tactaatacg agtggtagta aacaggaagt ttactattag aaaacttcga
    12661 ttcggaggaa attatggaaa ttggtgagaa gttaagaaat ttgcgcatcc aaaagaattt
    12721 gacacaagaa gaactaggcg aacgcacaga tttgtcaaaa gggtatattt cccagttgga
    12781 acgagattta agttcaccat caatggaaac attcttttct attcttgaag tcttaggtgt
    12841 gactccagaa gaattttttc atcaagaagc agcgaatctg caagtggttt attcaaaaga
    12901 agatcatacg gtttatttcg atgaagaaaa cgggtatgaa ttggaatggc tcgtggctga
    12961 ttcgaatgaa aaagaaatgg agcctgtctt gctgactttt gaaggtgcag gagaatataa
    13021 gacgtttgaa ccttcattat ctgaaacgtt tatttttgta ttagaagggg aattagagtt
    13081 aagcttagga gagacggtct atgtggcaaa agcaggacag tcgatctatt atcaagcgac
    13141 aaaacaacat caattaagga atcatctcaa aaaacgaaca aaagtattga ttgttgcaac
    13201 gcaatcatat ttgtaatata gggggtaaaa acgtggggaa accaatcatt tcatttgatc
    13261 aagtagtgaa acgctatgat gatgaaacag tattaaaaaa agtaagtttt gagatcgaac
    13321 aaggaaaatt ttatacactg cttggtcctt ccggctgtgg taaaacaacg atcctacgta
    13381 ttatagctgg attcaccgaa gctacagaag gggacatcta ttttgaaggg aaacggttga
    13441 atgatttgcc agctaataag cgacaagtaa atacagtctt ccaagattat gcactttttc
    13501 ctcatatgaa tgtttttgat aacgttgctt ttggattgaa gatcaagaaa atgtccaaat
    13561 cagatatcga aaagaaggta aaagatgctt tgcgtatggt ccagcttcct ggatacgaaa
    13621 aacgggagat tagtgaaatg tctggtggtc aaagacagcg tgtagcgatt gcacgagcaa
    13681 ttgtaaatga accgaaagta ttgctattag atgaaccgtt atcggcgctt gatttgaaac
    13741 tacgtacaga tatgcagtat gaactgcggg atctgcaaca acgattagga atcacgttta
    13801 tttttgttac tcatgaccaa gaagaagcgt tggcaatgag tgatgagatt tttgtcatga
    13861 ataaagggaa aatcgtccaa agtggtacac ccgtagatat ttatgatgag ccaatcaatc
    13921 atttcgttgc tgattttgtt ggggagagca atatcgtgga cggtgtaatg atcgaagata
    13981 atctagttga gtttgttggt aagcaatttg aatgtgtcga tggcgggatg cgtctaaatg
    14041 aaccagttga agttgtttta cgcccagagg atttgacgat cacgacacca gataaaggaa
    14101 aactagtcgt aacggtcgat actcagctgt ttcgtggtgt ccattatgaa atcatctgtt
    14161 atgatgaaca gcaaaatgaa tggatggtcc attcaacgaa aaaagctaaa gaaggaagca
    14221 aagtaggatt ggcctttgag ccagaagata tccatgtcat gcgtttcaac gagtctgaag
    14281 aagaattcga tgcacgtctt gacagctacg aagaataggg gggacaagaa tgaaaacaat
    14341 gcgcaggatc tattccgtcc cttatatttt gtggctcggt ttattcgtga tcgcgcctgt
    14401 attaatgatc atttatcaat ctttttttga tatgaatggg caattcacgc tgaataatta
    14461 tctatcttat tttacgtcgg ggacatcgct ttctatgacg atcaattctg tatggtatgc
    14521 atttttgatc acgtttttca cgctgatcat cagttacccg actgcttatt ttttaacaaa
    14581 actgaagcac aagcaattat ggctgatgct gattattttg cctacatggg tgaatctgct
    14641 gcttaaagct tacgcattta ttgggatttt cagtgtgcac ggcagcgtga atcatttctt
    14701 tgattttatc gggatcgggc cgaaacagat attattcaca gacttcagtt ttctgttcgt
    14761 ggcaacgtat atcgagattc catttatgat tatgccaatt ttcaatgcat tggaagagat
    14821 gaatccttct ttgatcagtg ctagtagaga tttaggcgcg aatagctttg agaccttccg
    14881 acgagtgatt tttccgttat cattaaatgg tgtgaaaagt ggtgtccaag cagtatttat
    14941 tccttctctt tctttattca tgctgactcg tctgattggc ggaaatcggg tgatcacttt
    15001 aggaacggct atcgaacagc atttcttggt tacacaaaac tgggggatgg gttctacaat
    15061 cggtgtgatt ttaatcattg ctatgttcat cgtgatgctc ctgacaggcg agaagaaaaa
    15121 aggaggtcgc tcataaatga aaaaatttaa atggtcgtat ctttatttag ggatcgtctt
    15181 tttattctta tatgcaccga tcttctatct gattttttat tccttcaatg aaggaggaac
    15241 gatgaacagc tttacaggat ttacttggga aaattatgaa gctgtttttg aagatacacg
    15301 tttgatcatt atcgtattga atacgttcat gctggctttc ttatctgcat tgatcgccac
    15361 gatcatcggg acatttgggg ctatgggaat ctattacacg aaaaaacgac gtgcacggac
    15421 agcgttgttg agcatgaata acatcttatt agtctctcct gatgttatta tcggtgctag
    15481 tttcttgatt ttctttacac tactaggatt cggattaggt tttcagagtg tattgctttc
    15541 ccatattgct ttcagcattc caatcgtcgt cttgatggtc ttgccaaaat tgcaggaaat
    15601 gaacgattca atggtcgatg cggctagaga ccttggtgct aataatttcc aagtagtcaa
    15661 aaatatcatt ttgccttatc tttctccagg aatcatagct ggatatttta tggcatttac
    15721 ctattctctt gatgattttg cggttacatt tttcgtcaca ggaaatggct ttacgacgct
    15781 ctcagtagag atctattctc gtgcaagaca aggaatcagt ttagaaatca atgcgctaag
    15841 tgcgttagtt ttcttgttct ccatgatatt ggtcattgga tactacttta ttagtaaaga
    15901 aaaccgtcca aaacggctga agaaaaacag aagagtacgc gagggggtgg cacggctgcg
    15961 atgaaaaaat tacaatctct gtttttaggt attctcatca ttattgcggt gctgctgctt
    16021 ggtgttcgtc aacttgaaaa aacaagtggc atgagtggag caaaggtact taccatctat
    16081 aactggggag attatatcga tcctagtttg atcacgaaat ttgaaaaaga atatggatac
    16141 aaagtgaatt atgaaacatt tgattctaat gaagcgatgt tcacaaaaat ccagcaaggt
    16201 gggacaaact acgacatcgc tataccaagt gaatatatga tccaaaaaat gatcaaagaa
    16261 aaactagtac ttccattaga tcattcgaag atcaaaggat taaataatat tgatccacga
    16321 tttttagact tggattttga tccagataat cagtattcga ttccatattt ttggggaact
    16381 ttagggatcg tatataacga taaattcttt gatgcaaatc aaattaagca ttgggatgat
    16441 ttgtggaagc cggaattaaa agacagtttg atgctgattg acggtgcacg agaagttatg
    16501 gggctttctt tgaatagttt aggctattct ttgaatagta agaatatggc acagctgaca
    16561 gaagcagcaa ataaattgaa tcatttaaca ccaaatgtca aagcaatcgt ggcagatgag
    16621 atcaaaatgt atatgatcaa tgaagaagcc tccgtggcag tgacattttc tggcgaagct
    16681 gccgatatga tgtgggaaaa tgaacattta cattatgtga tcccaccaga aggatccaat
    16741 ctttggtttg ataatatcgt tatgccaaaa accgtgaaaa ataaagaagg tgcctatgat
    16801 ttcatcaact ttatgctaga accggaaaat gcggcacaaa atgcagagta tattggttat
    16861 tctacaccaa atgaagaagc aaaagcgtta ttgccaaaag acatttcgtc ggacgaacaa
    16921 ttctatccat ctgatgacac gatctcccat cttgaagtct acaaagatct aggatcgaaa
    16981 tacctaggca tctataatga cctattctta gaattcaaga tgtataggag ataatggcaa
    17041 aactcagtaa gaatggggac ttatcaacgt tctaaagagc taaaaatcgt cctttttcta
    17101 tctgagtttt ccaatcttct accaaaagcg gatgaaacgc cgcttttttt gtgttatttt
    17161 attttttcta ccacgttttt ctaccagaga aaagtggaca aaaccattgt aaaatagggc
    17221 ccgagacggg ctagtaaatc taagattgaa aaagttacag aaggataaag taattggaaa
    17281 ctatgcaaat atacttaacc cttctgtaat ctattaataa aactaatata tgaatccagt
    17341 tcaatatttg tagctatgaa aaaacataaa aatcatatta gataaaaact aaattggtag
    17401 ataaattatt ttgtcagata tctgaggcaa atattcgact atttgtgttt caaagtaaaa
    17461 attggaatac aaatatagaa tagacatatt gcagccgata gtttattatg cttttagaca
    17521 cattaaactg gaggaaaaaa tgaaaaagag cgctaaagat cgagtttttg atgagctgat
    17581 acgactaaca gggaatatgt cttctgtcac tgccgagaaa atttcgaaga atctaggtat
    17641 ctctcgtcag aatgccagcc attatttgac gagattagtg gaagataaaa aggtcgagaa
    17701 attaccggga aagcctgttt tgtggaagcc tttagatgaa tatgcggttg tagataatac
    17761 ggagcaaata aacgaagcct ttcattctgt agttggtcat gacggaagtc tgagagaggt
    17821 cattcaaaaa tgtatagccg ctgtcaaata tccgcctaac ggactcagtg tattaataaa
    17881 tggagccacg ggtgttggaa aaagtttttt agccacaaaa atttttgaat acgctatcca
    17941 tgagcaaatt attgaaaaag atgcaccatt tgctatctta aactgtgccg attatgcgga
    18001 caatcccgaa ctgctttcgg caacactgtt tggatacaag aagggggcct ttacgggggc
    18061 tgaaaaggat accgatggtt tattggcaac ggccaacaac ggctatcttt ttctcgatga
    18121 ggtccatcgc ctatcgaaag aaaatcaaga aaagctcttt ctatttattg atactggaaa
    18181 ctatcgtcca gtcggtgaaa atgtaaattg gcattctgct aaggttcgtt ttattttcgc
    18241 cacgacggaa aaaggtgaaa attatttatt agacaccttt gatcggcgta ttcaaattag
    18301 tgttatgttg ccaacttttg aagatcgccc cattcgagaa cgattagagc tgattcaatt
    18361 attttttcaa aatgaagcgg atgttttaca aaaagatatt attgtttcaa gagaagcctt
    18421 gtctttaatg ttatctcatc cctttagtgg gaatattggt aagctgaaga atatcattaa
    18481 aatcagttgt gcggatgtgt atagtcgaac acaagaagaa ccattaacga ttgggaaaaa
    18541 tgagatcttg attcagttaa atatgctgga atccgaagta gaaagcttgc cgattgctag
    18601 tttattgata aagaaaaatc aaaagataaa aacggatcga atcaaaccgt ttgattatga
    18661 ttcgattttg gaaaaaatta ctcagctgat aaatgaaggt aatttcaatg aaaa
//
LOCUS       DADGKS010000056        18564 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.056, whole genome shotgun sequence.
ACCESSION   DADGKS010000056 DADGKS010000000
VERSION     DADGKS010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18564
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.056"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            6..305
                     /locus_tag="JXV47_002057"
     CDS             6..305
                     /locus_tag="JXV47_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAX1488080.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="JXV47_002058"
     CDS             378..1739
                     /locus_tag="JXV47_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HAX1488081.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="JXV47_002059"
     CDS             1761..2021
                     /locus_tag="JXV47_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488082.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="JXV47_002060"
     CDS             2035..2787
                     /locus_tag="JXV47_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HAX1488083.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="JXV47_002061"
     CDS             complement(2881..3486)
                     /locus_tag="JXV47_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAX1488084.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="JXV47_002062"
     CDS             complement(3539..4513)
                     /locus_tag="JXV47_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HAX1488085.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5670)
                     /locus_tag="JXV47_002063"
     CDS             complement(4891..5670)
                     /locus_tag="JXV47_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAX1488086.1"
                     /translation="MLLRVVGSIIFRYTLEEVNNVPKYEEIANILRERIRSKEYPLDS
                     FLPNQVDLVKEFGASRMTIKKAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEY
                     EGLSLQMKRRHRSLKSQIIHFDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVL
                     EHTFMPVHLVPGLKKEHLLASIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAE
                     NDPVLEVQQVVYLKDGQPIEYSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="JXV47_002064"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="JXV47_002064"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAX1488087.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="JXV47_002065"
     CDS             7161..8558
                     /locus_tag="JXV47_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAX1488088.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="JXV47_002066"
     CDS             8639..9079
                     /locus_tag="JXV47_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAX1488089.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="JXV47_002067"
     CDS             9227..9553
                     /locus_tag="JXV47_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAX1488090.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="JXV47_002068"
     CDS             9554..10303
                     /locus_tag="JXV47_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488091.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="JXV47_002069"
     CDS             complement(10383..10838)
                     /locus_tag="JXV47_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAX1488092.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="JXV47_002070"
     CDS             complement(11265..11540)
                     /locus_tag="JXV47_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488093.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="JXV47_002071"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="JXV47_002071"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HAX1488094.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12978..14429)
                     /gene="cls"
                     /locus_tag="JXV47_002072"
     CDS             complement(12978..14429)
                     /gene="cls"
                     /locus_tag="JXV47_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAX1488095.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14770..17436
                     /locus_tag="JXV47_002073"
     CDS             14770..17436
                     /locus_tag="JXV47_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAX1488096.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17800..18552
                     /locus_tag="JXV47_002074"
     CDS             17800..18552
                     /locus_tag="JXV47_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAX1488097.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
BASE COUNT         5964 a         3212 c         3832 g         5556 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaag
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag ttgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    12721 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    12781 aggtcgtgag cctgccgtcc agctccgagt cacaaggaac aagttcaaaa aacagcttct
    12841 catgtttgtt gaatattgtg acttgtgacc gaggagttgg caggagaaca ccgtttgttc
    12901 ggaagaaggg actgtgacaa gatttttgtc acagtccctt taatcttagt atatttttct
    12961 ctacttgaat aaaaaaatta taggattgga gaaaataatc gagaaatttg ttgcttgaat
    13021 aatagccagt tagacatttc cttgactgtt tcagttgtca tggatgaaca atgtgtctca
    13081 tcttctttga actgagtagc aagttcttct aaaaactcag gatcgtaaat gacagcactt
    13141 gtttcaaaat tcaatcggta gctacgaata tcttgatttg ctgaacctac catgcagatt
    13201 tcatcatcca ttatcaatgt ttttgcatgg aggaagccgt tctcatagac aaggatttgt
    13261 acattttcct tgatcagctg ccgagcataa tattgtgttg ctcgataaat aaaaggatga
    13321 tccggtttgt tgggaatcat gattttcaca tctacaccag aggcagttgc gatttttaaa
    13381 gcagcaatga cactttcatc aggaacaagg taaggtgtct gtatccaaac acgtttttta
    13441 gcagaagtaa tcaatttgat aaatgaaagc ttgatttgtt ccctttcgtt attcggtccg
    13501 cttgaaacaa gctggatgga tgtatcagca agcttagatt catctcgatc tgctttttta
    13561 aagaaataat tcaaatgata gccgaccttt ttttcttcag gtaccgagac gttccagtct
    13621 gttaagaagc gaagctggag caaagaagaa gcggcaccga aaatccgtat atgcgtatcg
    13681 cgccaatagc cgaatttttt tgttgtattt acatattgat tggcaatatt gaaaccaccg
    13741 gtataactaa tctttccatc gatcacaacg atttttcggt gatcatggta attcaatcgg
    13801 aaacgaagta atgccctttg tgaggtaaca aatgtatgga catgtccacc atttttgatt
    13861 agacgattga aatcttttgc ttttgtgcca tgagagccaa atgcatcata taatattcga
    13921 acttccacgc cttctgcggc tttttcttct aaaacatgta agacttgctg gccgatatta
    13981 tctgtcacaa atgcgtaata ttcgatatgg atcgaatgtt tggctttttt tagatcttga
    14041 agcagtgaat ccaatttctc ttgtccgtct gtgagaagag tgacagaatt cattcttgtc
    14101 agcggcatac gatttaatga agagaagaag tcaacaaatt gctgtttgtc tttatcgccc
    14161 atgtcaggat cgtaatgttc aatggtatct cctctaaaag actgaaagtt ttctaattct
    14221 ttcaagtcac tttgtcggag atagaatttt ttcttatccg ttaatccacg tccgaaaaat
    14281 aaatataata caaagcccac cccaggaagg gcaaacaata ctaagagcca tgcccaaatg
    14341 gctgctacat ctcggggttt gatcaaaata gccaccaaag caataagtgc atttaataga
    14401 taaagggcgg ttataatact agataccaca aaaatgttcc tccttacata caataacatt
    14461 agtatagcat gatagaagaa agaagcctac caaggtgaat atacttttca ctcctttcat
    14521 gaaaatgtag gtaaatcggg ctaaagtagt tgctttttgt aggttaataa ggtaggatat
    14581 tagtacagtt gaatatctcc ttaggggagt aaccggcaac gtttgttgcg ataatatcaa
    14641 cagtaagtta accaaatggt tttctggtat tgtatgaaat ggtgagacct aagacaaatg
    14701 cgtatttgtc ttaggtctct tttttttcag acaggactag ggccaagatc aaaaaatggg
    14761 ggatgaaatt tggaaaacaa ggaacaagca caacaagcgg tctataaaga aacgatcgac
    14821 tcgttgatgc agcaaacgca gagctcaacc gatggattga gcaccacgca agcgaaggaa
    14881 aaattagaaa gagatggctt gaaccagcta aaagaaaagc cgaagaagcc aacttggaaa
    14941 ttgttcttag aaactttcaa agatgcaatg gttatcgtat tgctgattgt cgcactgatt
    15001 cagatggtca tgggtgacta catcgaattc ttagttattt ttgcagtatt gatgttgaat
    15061 tctataatca gtgttgtcca aacaaaaaaa gcagaaggtt ctttagaagc gttgaaaaac
    15121 ctttcagcgc ccgatgctcg agtgattcgt gatggtaagg aaaaaacgat tccggcaaac
    15181 gaacttgtgg taggagatat cgtgttgtta gacgcaggcg attatgtacc tgctgatgga
    15241 cgtttactag atgcgggatc attaaaagta gatgaaggta tgctgacagg agagtcgact
    15301 tctgcagaaa aagaagtaac ggatatcaca agtacggtac caatcggaga tcgtacaaat
    15361 atggtattca gtggaacgat cgtaacttac ggacgcggta aattcttagt gacttcaact
    15421 gggaataata cggagatcgg acaagttgct ggccttttgg aatcaacaac tgagcaagtc
    15481 actccgttac aacgaggtct ggataaattc agtaaaaaac taagtttggc tattttggca
    15541 ttgtctttat tgattttagg tatccaactg tttcgtattt atcttggaga aggtacagga
    15601 gatatgactg cagatatcgt cagcgcagtg atgtttgccg tagccgtagc cgtagctgct
    15661 attccagaag cattacagtc tatcgtaaca atcgtgttat ctttgggaac gaataaaatg
    15721 gcaaaacgtc atgccattat tcggaagctt ccagcagttg aaacacttgg ttcgacaagt
    15781 atcatctgta cagataagac tggtacattg acacaaaaca aaatgacagt tgttgactac
    15841 tttttaggta atggcgatac tggggatttc acaaatgacc cttcaaaatg gacagctgac
    15901 gaacgtcgct tgatcgaaat cagtgtttta gcgaatgatg catcgatcag tgaagacggt
    15961 actaaattgg gcgaccctac ggaagtagcg tttatcgact ttagtgaaaa attaaaccag
    16021 ccttatcagg aaatccgaaa caactaccca agacaagcag aacttccttt tgactcagat
    16081 cgaaaattaa tgtctactgg acacacaatt gataacaaaa attacttgtt tgttaaaggc
    16141 ggaccagata tcgtcttcca acgcagtaaa aaagtattgc taaatggtga agtcgttccg
    16201 atgacggatg aattgatgaa aaaattccaa gagcaaaatg aagctttttc aacacgcgca
    16261 ttacgtgtac tagcttttgc ttaccgtcca cttgataatt ttgatttatc atttgaagat
    16321 gaagacgatt tgatccttgt tggtttgctt gctatgatcg atcctccacg tgctgaagtg
    16381 actcaggcgg taacagaagc aagaagtgca ggaatcaaaa caatcatgat tactggtgac
    16441 cacaaaacaa cagctgttgc tatcgcaaaa caaatcggga tttttgaaga aggaaacctg
    16501 gctttgaccg ggacggaact agatgaattg acagaagatc aactaaacga agttttagaa
    16561 aaagtcactg tttatgcacg tgtttcacct gagaataaaa ttcgtatcgt tcgtgcttgg
    16621 caaaataaag gtcatatctc agctatgaca ggtgatggtg taaatgacgc accagcattg
    16681 aaacaagcag acatcggaat tgctatggga acgggtacag atgtggcaaa agatgcagca
    16741 gcgatggtat tgacggatga taactttgct tctattgtca gcgcagtaga agtaggacgt
    16801 aatgtgtttg ataatatcaa gaaagctatt tcttatctat ttgcaggaaa tttaggtgcg
    16861 atcattgcga tcatctttgc cttagttgct gactggtcca atccatttac agcattacaa
    16921 ctgttgttca tcaatttagt caatgattca ctgccagcaa ttgcattagg tacagaaaaa
    16981 gctgaacctg ctacgatgaa ccgcccgcca agagatccaa attcaggaat ctttacggac
    17041 aaaacattga tttctgtaac gtatcgtggt gtgctgattg ggattgctgt tatctttgct
    17101 caatggcttg gcatgcagca ttcacctgaa ttcggtgtag ccatgtcatt ttcaacattg
    17161 atttggtgtc ggacattgca aacattccca gcacgttcaa acacacaaac agctatccaa
    17221 gcagggttct tctctaacag aagtgtctta ctagctgtag ttgtatgtag cgcgctttac
    17281 tgcttaacaa tgatcccagg actgaaagaa gtcttctcta tcccatcagc atttggattg
    17341 acagaagtct ttacatgtat gggaatcgca cttgtgacaa ttgttttgat ggaaatcact
    17401 aaattgatca ttgtacgagt acaaggaaat aaataaaacg aatcaacgag gttgtgagcc
    17461 tgccgtttaa ttctgagtca caaggtgcaa tttcaacaaa cagcttctca tgtttgttga
    17521 atattgtgac ttgtgaccga agagttggca ggagaacacc gtttaaggaa gaagttgtaa
    17581 aatcagcatt ttgagctaat actgagggtc atctgattgg acactgttta ttcggaaaga
    17641 gggactttga cacgactttg gtcacagtcc ctttttttat ttatgataga cggaaagcca
    17701 atcattttat tattcatcaa aagagataga atagataaaa gaggagaatg atttattccg
    17761 aaaagtgaaa acatataaca aaaaattaga ggaaatcaaa tgaatgaaaa agaatgggat
    17821 gaatttgctg aagaatatta tgaaatccag caagaatcgc aagtaactat tgctgaagat
    17881 gtaaaaaatt atctgaaaac ggagaaagtc ctgcctgctg aaacagcagc agacgttgct
    17941 ggaggatctg gcagatttct ttccttagca aaagaaatta atcgctatga tttgatcgat
    18001 ttttcttcag gaatgctaga aaatgcaaaa aaagaagcag aaaaaaatga gttgccaaat
    18061 gtttccttta tcaaacagtc gttagaagaa tttatccaat caaatgagac atatgaaatg
    18121 gtttttacag cagcaaatcc agcattggta catcttattc aattagaaaa attgatgaaa
    18181 aagtcaagca aatggtgcgt gataatcaga gtagtggaat caatcgatga tgttttttat
    18241 cctatcgaaa agcaactagg aatgatagaa gaagatccta atacatcgcc agttgtaatg
    18301 gatcaatttg aaacatactt aattgatgaa ggattcaaag tgaagaaaaa agattttact
    18361 tattttacac aggaatcaat tactgaagaa ttgatgaagc tatactatga cgcgtacgca
    18421 aaagatcctg ttgtgaccag gtacattcgc aaactattca gtgaaaaacg agaaatcctt
    18481 agtacgacta agctgaccta tagactgctc ctttggtccg cagataaaaa aagaaccttt
    18541 cacgactcgt gaagggttct tttt
//
LOCUS       DADGKS010000057        18007 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.057, whole genome shotgun sequence.
ACCESSION   DADGKS010000057 DADGKS010000000
VERSION     DADGKS010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18007
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.057"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(587..1612)
                     /locus_tag="JXV47_002075"
     CDS             complement(587..1612)
                     /locus_tag="JXV47_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAX1488098.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            1887..3572
                     /locus_tag="JXV47_002076"
     CDS             1887..3572
                     /locus_tag="JXV47_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HAX1488099.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            3586..4869
                     /locus_tag="JXV47_002077"
     CDS             3586..4869
                     /locus_tag="JXV47_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAX1488100.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            4939..5808
                     /locus_tag="JXV47_002078"
     CDS             4939..5808
                     /locus_tag="JXV47_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1488101.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            5805..6641
                     /locus_tag="JXV47_002079"
     CDS             5805..6641
                     /locus_tag="JXV47_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAX1488102.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            6667..7734
                     /locus_tag="JXV47_002080"
     CDS             6667..7734
                     /locus_tag="JXV47_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HAX1488103.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            7731..8558
                     /locus_tag="JXV47_002081"
     CDS             7731..8558
                     /locus_tag="JXV47_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAX1488104.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            8603..9628
                     /locus_tag="JXV47_002082"
     CDS             8603..9628
                     /locus_tag="JXV47_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAX1488105.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            9625..11808
                     /locus_tag="JXV47_002083"
     CDS             9625..11808
                     /locus_tag="JXV47_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAX1488106.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            11808..12938
                     /locus_tag="JXV47_002084"
     CDS             11808..12938
                     /locus_tag="JXV47_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAX1488107.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            12935..13612
                     /gene="pgmB"
                     /locus_tag="JXV47_002085"
     CDS             12935..13612
                     /gene="pgmB"
                     /locus_tag="JXV47_002085"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAX1488108.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            13696..14223
                     /gene="msrA"
                     /locus_tag="JXV47_002086"
     CDS             13696..14223
                     /gene="msrA"
                     /locus_tag="JXV47_002086"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAX1488109.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(14424..15110)
                     /locus_tag="JXV47_002087"
     CDS             complement(14424..15110)
                     /locus_tag="JXV47_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HAX1488110.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            15190..16728
                     /locus_tag="JXV47_002088"
     CDS             15190..16728
                     /locus_tag="JXV47_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HAX1488111.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            16848..17315
                     /locus_tag="JXV47_002089"
     CDS             16848..17315
                     /locus_tag="JXV47_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HAX1488112.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            17753..>18007
                     /locus_tag="JXV47_002090"
     CDS             17753..>18007
                     /locus_tag="JXV47_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HAX1488113.1"
                     /translation="MVLFAPQRAPETRSVCQTSELKLEENNVRTTYMAKPGEVERKWY
                     VVDATDVPLGRLSTVVASVLRGKNKPTFTPHLDTGDFVIVI"
BASE COUNT         5842 a         3255 c         3885 g         5025 t
ORIGIN      
        1 aaaaagaggt tgtgacaaat tattgtcaca acctcttttt tggtttgtct aaaataattt
       61 gtctaactag aagaaaagtg ggaaaggatc ttaacaacat cggttcgtat ccaattaagg
      121 tatcggaacg atcatcttcc aagagaagtc aatcaacaaa agtaaagata gatcattttt
      181 tgaatgcaaa ataaattgat gggaagatag agcggttatt tttaatattt tgctagctat
      241 tattgaataa ttcctcgaat aaaacaaaac cagtagacat gtctgttatt ctatttatgt
      301 tttagagata agtatcccca aataacatgg attgaaataa gggtaaatgt gtttaaaaaa
      361 acgaactata aaaacttata cacaacgtgg ttaaaaatag ttttttcttc cctgtggaaa
      421 aaatagttta acacaaacat tatagttatc cacagctatc taaaacagat ggaaaataag
      481 aaaaattcgc taaaataccg ggagggggta acgagggatg agtgattgaa aaaagaacag
      541 agtaactgac ttatcctcag tgtttctgtt cttttataat tctgttctac atttcttgtt
      601 gttggatcga atctgtgaga gtaatctcgg ttgaaagaat gattcttttt tcttcagggt
      661 attggtggtg gattagttgg aataaaagtt ctgtggcttt gattcctaac tgatttgtcg
      721 gaatgtctat ccgagtcaac tgtggcgaaa atagggagga caataaggga tcactgaatc
      781 ctgcgatcga aagatcatca ggtatctgct ttccagattg ttctgccact ttgtaaatac
      841 tcaatgattt taatgcatcg gtagaaaaaa tcgcagttgg tctttctcgt agcttcatta
      901 aatcattcat tgctgccatg ctatcttcta agcgaaagcc gccgtctata atccattcat
      961 tacggatatc taggtggtga tcaaataagc attgacggta accattgaga cgatcattgg
     1021 atacataaac ttctgtcgga gcatggagac agccgatatg acggtgtcca ttcttgatca
     1081 gtgtttccac caaatcgtaa ctatcctgga aattatccgt gtccactgag tagatgttcg
     1141 tgtagtcgtt tccgactttt ccgattacca caataggaat attgtattga tccaattcaa
     1201 aaagaagtgt ttcatccatc gtagagctta aaataataat tcctcggatc attttttctt
     1261 ggatcttttt cgcgcatttt tctagctctt cttctggtgt ttttgccgtt tgtagaatca
     1321 agtcgaagtt attttgttca gaaacggcag aaatggattg aataacatct gaaaaaaaag
     1381 gattgccata ggtcgtatga gaagtacgat gagataatgc tagaatcgcg tcaaaaccat
     1441 ttcctgacag tcctcttgca attttgctcg gttcataatt caattctttg attgcttgaa
     1501 gtacacttgc ttttgcttta tcagagatat ttggctggtt atttaatact ctggagacag
     1561 ttgattttga gacattagct tttttcgcaa tgtcataaat agtaggtttc aattttatat
     1621 gcacctcctt tttgggagcg ttttagaata attccatagt acaatagaca ttcttttttg
     1681 tctatgattt tgaaaattta ggaatagctt gcatgatcat gagagaccat atttttttaa
     1741 gaagctatta attattgata cataagcttt cttatttgta tttttgtgta tatcaaaatt
     1801 atttaaaaaa atgctattga cagtaagcgt tttccataat atgatcaaat cgttgggaac
     1861 gctcccaaaa aagaaagggg aatccgatgt atacaaaact tttacaagcg atttatcgcg
     1921 actcagattt gtctgagaaa accgcctcta tgattgaaca aaaagtcagt gtttatcagc
     1981 agaagaaagg ccaggcaggc aaactgcatt gggacgaaga agatattttc ttgattactt
     2041 atggggatca attttttgaa gagcagcaac caactttgcg tacatttaag aaattttatc
     2101 aaaagtattt ggcagataca tttagagttg tacatttctt gccatttttc ccatatacat
     2161 ctgatgatgg tttctccgtt gtaaattatc aggcaatcaa cgaccgtttg ggcacatggg
     2221 aagatataga agaaatgaga agcgaaacac ggttaatgtt cgactttgtc tgcaatcata
     2281 tgtctgccga aagtacttgg tttcaggaat atttaaactt gaatgatacg tacaaagatt
     2341 tttttattga tttgccactg gatacagata caagcagcgt gactagacca aggaccagcc
     2401 cgttacttac aacgttcatt gacaaaaacg ggaaagaaaa acacgtatgg acgactttta
     2461 gcgaagatca agtagacttg aattttaaaa atccagaagt tttattgaaa atgatcgata
     2521 ttcttttgtt ttacttagaa aaaggcgctt catttattcg cttggacgct gtgggatttt
     2581 tatggaaaga actaggaact tcttgtatac acctgccaga aacgcataaa atcatccaat
     2641 tattccgtgc aatcgctgat gaagcagctc caggaacggt attgatcact gagacaaatg
     2701 tgccacacaa agataatatc agttattttg ggaatggcga gaatgaagca cagatggtct
     2761 atcagttttc gctaccacct ttgacccttc aagcgattcg ttcgggtaat acaagtaagt
     2821 tgaaagaatg gttaaaaacc atcgatttcg catcgaaaaa aacaactttt tttaattttt
     2881 tagcctccca tgacggtatc ggattgaatc cggtacgagg tattctgccg gaaaaaacga
     2941 tccttgaatt agtggaacag ctgaagaaag agggtgcccg agtaaactac aagaaaaacc
     3001 cagatggaac gaccagtcca tatgagataa acgctacgta tctagatgcg ttaagttctc
     3061 caacagatac gacggaatgg agaagcaaac gctttttagc tgctcattca tttttggtaa
     3121 cgttaccagg cgtgccggca atttatattc aaagtgtgct gggaagtcga aatgattaca
     3181 aaggcgtaga aaaaacagga gagaatcgaa aaatcaatcg gcaaaaattt ttgttagcag
     3241 atattgagaa agagttgcag acagatccat taagaacagc agtatatggt gaattgaccc
     3301 agatgctatc tattcgaaaa aaagaaaaag ccttccatcc gaatagtttg atttacttac
     3361 tggactcagc agattctttt atcagtttta ttcgcgaagc gaaggaagag aaagtcttag
     3421 ttatccataa tttttccaat caatcagcag gttatctttt accaaaagga gattacctag
     3481 acctgttttc tggacaaatt atccattgca gtcaagaacg aaagttgata ttccagccgt
     3541 atgaatatat gtggctgaaa ataataaaat aagaggtgga aaaaaatgaa aaaaattatt
     3601 gttactacct gtctgctagc tactggattt cttcttactg cttgtggtga aagtcaaagc
     3661 tctaacgaat cacaacagac aacgattcaa ttcatgcact cttctgtcga acaggaacga
     3721 ttaagtgtga tcaatgaact ggttgctgat tttgaaaaag aaaatccaga catcaaaatc
     3781 aagcaagtgc cggtagaaga atcagcgttc aatacaaaaa tcgttacgtt agctcgttcc
     3841 ggtaaattac cagaagtaat ggaagtcagt caggattttg ctaaagtgat ggataaagat
     3901 gaactgattg atcagacggc agtccaaaac gttatcgagg aagctggaga agataattat
     3961 tatgacggag ccaaaaacct tgttcgttca gaagatggaa aaagctatat tgctgcacca
     4021 attagcggct gggttcaagg tatttggtat gacaaagaaa aattatcaga agctggtttt
     4081 tcagaaccag aaaattggga tgatatttta aaaattgctc aacatttcac agataaagag
     4141 aataaacaat atggaattgc tatgcctact gctgaaggaa caatgagtga gcaagcgttc
     4201 tctcaatttg ctttgtcaaa tggagcaaat gttttggatg atgaaggcga ggtaacgatc
     4261 gatacggaaa agatgagaga agcattgtcg ttttatcaaa acttatccca atacacgatg
     4321 ccaggctcta atgatgtgac agaaatcaaa gatgctttca tgaatggaac agcaccaatg
     4381 gcaatctatt caacttacat tttgccttct gtttatgaag cggggaactc agaaaatatc
     4441 ggttttgcta tcccaacaca aaaagatcaa gctgtctatg gcacagtatc tggattgacg
     4501 atttcttctg gtctagacga gaaacaaaaa gaggctgctg aagcattcac agctttctta
     4561 tctcaaccga aaaacatgga aaagtgggtc ttgatgtctc ctggtggtgc tcaaccagtg
     4621 aataaacaag tagtcgaact ggatggttac aaagaaaatg aagtcatcaa gtcttttggc
     4681 gagctgccat ctgagattgc tagtgctttt gatgaagtac aagtctttgg actagtcggg
     4741 gaaaagaatt tcacgaaaat gggagatatc acaagctcag gtgtgatcgg aaaagcagtg
     4801 aaccaagtaa ctgtcggaaa cgaagatgtc gatcaagctt tagctgacgc acaaaaaaat
     4861 acgaaataac aagaagttct gccaatggtg ttcgaaaaaa gtagatagct attggcagat
     4921 tatcaggggg aggtttcaat gaatcgtcca aggaaacatt ctgacttaaa attagccatg
     4981 ggacttttag caccaagcat gcttttatta gctgttttag tgctgattcc aatgctttcc
     5041 aatattcaga tcagtttttt cgatatgccg ctgaatccta actcagacgc cgtttttatc
     5101 ggattaagca attatcttga aattttaagt gatagtgaat tttatcgttc tttaggttta
     5161 acagttgctt acacattctt agttgtagca ggcagtacag ctttaggatt agccgtagct
     5221 attttgctta accgcaagtt cagatttagg aaaacggtgc gttcactgat tttattaagt
     5281 tatgttacgc catctatttc tttgattttt gcttggaaat atatgttcaa taatagttat
     5341 ggaatcgtca atgatctgtt agtagatagg ttgcagcttt tcaacgaagc accgctgtgg
     5401 ttcgaccagc cagttgctag cttctttatg gtcgttttgt ttgctatctg gagatactat
     5461 ccgtatgcgt ttatttcatt tttggctatt ttgcaaacag tcgacaaaac gctttatgaa
     5521 gcagctgaaa tggacggtgc aaatgcttgg cagaagttca agatcgtgac actgccggca
     5581 atcaaaccag tactagcaac tgtgattgtt ttacgatcta tctggatgtt ctatatgttt
     5641 acagatgtct atctactgac gaataaagtc aatatcttag gcgtttattt gtatcagaca
     5701 gcctttgcgt tcaatgatct tggaaaagca gcagctatat cgattctatt gttcatcatt
     5761 attgcagcgg tcgtcttgct ctcacgaaag aaggtggact tgaaatgaaa aataaaaaga
     5821 gcaggaaaat cttattttac gcgacgattt tgttgctatt agctgtcaat ttgtttccat
     5881 ttttgatcat gctgatgaca tcattcaagg attcacaaga agcaattgca acgacacaaa
     5941 ctatttttcc gaaagaatgg acttttgaac attatcagga tattttcaat gctgagattt
     6001 ttccattcat catgtatttc aaaaatagtt tagtgatctc cttgatagcc tccgtaactg
     6061 cagtagtgat tgggatcagc ggggcatacg ctttgtcaaa actacgcttc aaagctcgct
     6121 cgaaaatcaa tgctagcttt tacaccgttt atatgttttc cggtattttg atcgttgttc
     6181 cattatttaa aatcatttcc ggtctaggtt tgtatgatac caatacagca ctgattatca
     6241 cgatggtcgt tcaaacactt cctactgcga tattcatgct aaaaagttat tttgacacga
     6301 ttccgactga tattgaagaa gcagcaatga tcgatggtct tagccggatc cagatcatta
     6361 ttcggatcat tataccattg gctatttctg gaatcatttc tgtcttcgtt tattgcttta
     6421 tggtttcgtg gaatgattat ttatttgctt cgattttcct gtcgacctcc gaaaaattta
     6481 ctttaccaat cggtttgaac acattattca gtacaccaga ctacatttgg ggacgaatga
     6541 tggccgcttc attggtgacc gctttaccag tcatcattat gtatgcgtta tctgaacgat
     6601 ttattaaagg tgatttagtc gaaggcggcg taaaaggata aaaagaaaag aaagaggaaa
     6661 gaaaagatga aaaaattagt tgcattagaa ccaagaatag ccggattcaa agattacgaa
     6721 gaccgtgaga tcgaaaagaa cgaagtacgt atccgagtaa ttttcgctac tccaaaacca
     6781 ggaacagaaa ttgtcgactt tagaggatta agtccattta tcgatgaaga attttcagaa
     6841 gaatggcgcc tattcttgcc aagagaagaa ggaagccaac gcggtgtggt atttggcgaa
     6901 tttcaattag gaaatatgat tgtcggtacg atcgaagaaa cgggcagttt ggtgacagag
     6961 tatcaaaaag gagagttagt ctgcacttat ggacccattc gtgaaacgct gattacaaac
     7021 ggtgttgata attataaact acgtaaactt gatcggttgg atcaatggaa aaatgcagta
     7081 tgttacgatc ctgctcaatt cgctttaggt ggtatccggg aagcacatgt tcgagcaggt
     7141 gatgctgtag caatcttcgg tttaggcgct atcgggcaaa ttgcgattca attagctaaa
     7201 aaagcaggtg ctactaccat cgttgggatc gatcccatag cgcagcgtag agaattagca
     7261 gaaaaatacg gtgccgatta cacgctagat cctatgaaag cagatgtcgg ttttcgtcta
     7321 aaggaattga cagataaacg tggagtagat tcagttattg aaacgagtgg cagtgctgcc
     7381 gcattacaag cttctttaag agggatcggc tatggcggga tcatttctta tgttgccttt
     7441 gctaaacctt ttccagctgg gtttaatctt ggtcgcgaag cacatttcaa taatgcaaaa
     7501 atcgtctttg ctcgagcatc tagtgaacca aacccagatt acccaagatg gaaccgtaaa
     7561 cgaatcgagg acacatgttg ggaattattg atgaacggtt acttggattg tgaagaaatc
     7621 attgatccag ttgtgccatt tgcagaaagc gcagaagctt acatgcgtta tgtagaccag
     7681 cacccagaag aaagtatcaa aatgggcgtt caagtccgag gaggagaaca atgaaattcg
     7741 gtacgcaaga tcaagcattt ttcccaagag acattttaga aaaatttaga tttatcaaag
     7801 actgtggatt tgaagaatac gaaatcgacg gtaagttgtt aatagaaaat atcgacacag
     7861 tcaaacaggc aatcaaagaa acagggatcc cagtagtgac agcttgtaac ggctacgatg
     7921 ggtggatcgg tgactttatc gaagaacggc gtcttaatgg tgtacgtcaa attgctgaga
     7981 ttttgcgtgc actaagcgag gttggaggca aaggaatcgt tatcccagca gcttggggaa
     8041 tgttcactta tcgattaccg ccgatggttt caccccgaag caaagaagga gactataaag
     8101 cagtcagcga atcacttcgt tatttagata aagtagccga agaaacaggt acggttattt
     8161 atttggagcc tttgaaccga taccaagacc atatgatcaa tttgttagcg gatgcgcgtc
     8221 attacattga ctctaatcaa ttgaaacatg tgcagatcat cgctgatttt tatcatatga
     8281 atattgaaga agatgatatt tcaaaagcat tgactacgca aaaagagtat gtgggtcata
     8341 tccatttagc agataatcat cgctaccaac caggatctgg cgcaattgat tttactcgcc
     8401 attttcaaac gctacttcaa aatgagtatg aaggttatat ggtatatgaa tgtcgtttgc
     8461 gaggagaaaa tgaagtgaaa atttatcagg aatcattgca atacttgaaa aactgtctgg
     8521 aaacagcgcg tcatttaaat gatttagaga aagaatagag aaagaataac aataagtaaa
     8581 taagcaaagg agggagaaat aaatgaagaa agtagcaatc ataggcgctg gacaagtagc
     8641 agaaaaagta catgctgctt attatcaaaa aagatcagat gtcttagaat tggccgctgt
     8701 ggttgatcca gtcagccagc gagcagaaga cttttgccga cgtacaggat tttctcatgc
     8761 gtatacatca gttacacaaa tgctgaatga gatttctccc gatatcgtga gtgtctgtac
     8821 acccaatcgc tttcacttcg aacatgtatt ggctgccctc gaagctaatg cttcagtgat
     8881 gtgcgagaaa ccaccagcta tgacagctga tcaagcaaga aagatggcag agacagccga
     8941 taaaaacggg cagattttgg cttatggatt ccagcatcgt ttttctgacg aagcaacaat
     9001 gatcaagaat catcttgatg ttctcgggga tatttattac gtagaagcga atgcgcttcg
     9061 tcggtctggt gttccaggct ggggaacgtt tatcgacaaa gaacttcaag gaggcgggcc
     9121 tttgatcgat tatggcattc acatgcttga tacagcgatg tatattactg gatttcctaa
     9181 agtaaaaagc gttcgggcgt acagcttcca aaaaattggt acgaaaaaaa attcagggaa
     9241 attcgggaaa tgggatccaa gcaaattcac agtagaagat gcaatttttg gcacactgga
     9301 attagaaaac ggcaagatca tccaactgaa tacttcgttt gctttgaata tcagagaaga
     9361 caaactgaat gtggcttttt gtggcgatca ggcaggtgct aatctgtatc caggcgaact
     9421 attcgaagat gtagatggaa agctggtttc cttacaaaag accacgccag ttaatgaccc
     9481 acatgaacta agtatggctc attttgtgaa tcgggcgctc ggtgaccaga ctcagatgat
     9541 tgcagatggc tggcaaggat atgtcatcca gaatctggtg gaaaatttat atcgttcggc
     9601 agaaacagga gaagttatta ccttatgaaa gtagaagaaa aacagtttga tttagagtat
     9661 atcaataagt atgcgagtca gatgaccatt ggaaatggat tttttggtat cagaggaagc
     9721 caggaggaag actatcggaa tcaagtaagg ggaatgtttg cagctggtgt atataaccga
     9781 cctttaggag cagaatcagc cgagttagtg aatctcccag atgtcatcag atgggaaata
     9841 aaaatcgacg gtgaacattt ttctcttgag acgatgaaag ttcttgcata cgagcgggca
     9901 ctagatttag aaatgggaga gcttaaacgc tatgcgctca ttgaaactgc tcaaggaaaa
     9961 aaagtggaag tcattacttg tcgtgttgct gatcaaaata atctccatca ggcagccctg
    10021 aaagtggtca tcaagccgtt gaccgaagac tgccaagtag atgtgaaaac gggtatcgat
    10081 ggacagcaaa ccaattttgg tacacagcag ttggttgaaa aagaactgcg agtatttggt
    10141 gacgatttga tcagtgcatc ctaccagaca acagaaagta aaattgatat tgggattgca
    10201 gctaaattca ataaagcagg tgtattccaa gcaaaaaatc gccggatcac cgcttccttt
    10261 tcagaaaaga tcagaaaaaa tacgtccttt acgctggaga agatcatcgt gctctctacc
    10321 tctcttcagc aaacagaccc gtttaagaaa agtattgccc aagcccagaa aagcgttagt
    10381 tatacagaaa ttttagagca gtcgatgtct tattggacag atttttggca tcagcatcgg
    10441 ataacgatcc aaggcgattc ttctttcgat cagttagcga tggacttcgc tgcttaccat
    10501 ttacagatta tgactccccg caatgatcca agtgttagtg taggggcgaa gggactaact
    10561 ggcgaaggtt ataaagggca tgttttctgg gatacggaaa tttttatcct gcctttcttt
    10621 ttatatcagt ttcctgaagt agcaaagaat ttgctgctgt accgttatga tcgattagaa
    10681 ggcgcacggc aaaaagcaag agattatcac tatcaaggtg cacttttccc atgggaaagc
    10741 gcacacactg gtcaggaaga gacacccaaa tttgctgcat tgaatatcaa aaccggaaca
    10801 agacaagaag ttgcttcagc tgccgcagaa catcatatca gtgcagacct tgcttatgcc
    10861 gttcaagagt atgtccaagc aacagaggat caatcgtttt tagaaacaaa gggaaaaacg
    10921 ctcattcatg aaacagcagc tttttggctg agcagagctg taaaagtcga tgatcattta
    10981 gagatacaca gagtcattgg tccagatgaa tacacagaat atatcgacaa taatgcatat
    11041 acgaactatc tggcgcatta taatgtggcc ttagctgtta aatatcaagc tggcgatccg
    11101 ctttttttga aagaatgtca aaatttttta gataagttat atttgccagt gcctaacaaa
    11161 gaacagctga ttccgcaaga tgacacgtat ctcagtaagc cagttattga tttgaccact
    11221 tacaaagaac gtcctggcag ccagtctatt ttacttgatt atgcccgtag cgaagtaaat
    11281 gaactccaag tcagcaagca agcagatctt gtcatgctgt tatacttatt acctgagtat
    11341 ttttctcaac caatcgtttc taagaatttg cattactatg aaaacaaaac aatccacgac
    11401 tcatcgttga gtaaagcgat tcacgccata gaggcttgcc gtatccaaga aatggaatgg
    11461 gcgtatcatt tattccaaga agcgtgcctg attgatttag gaccagatcc gcattcatca
    11521 gatgacggaa ttcatgctgc ttcattagga gcactatggc tagcagttat atttggtttt
    11581 tcaggtatta cagtaacgaa tggaactctt tctatttctc caagacttcc ttcagcatgg
    11641 gaaaaaattt cttttccttt tatttggaaa aatcacaggt tgctatttgt tttgacaaaa
    11701 aaacaaatag taataaaaaa agagacgaaa gaaacattac ctatttttgt caatggagac
    11761 caataccagc tggaaaaaga actgatcttg gaacggaggg gaaaataatg cgtattctga
    11821 ttgcgccaga ttctttcaaa gaaagtctga cagccttaga ggcagcacaa gccattcaat
    11881 caggttttca agaagttttt gttcaggctg aatatgatct gctacctata ggcgatggag
    11941 gagaaggaac ggtttcatca ttagcagaca gtttaaggtt gaagcggcaa acagcagtcg
    12001 ttactaatgc atttggcaaa aacaaagaaa tccagtacgc ttcagacggt caaactgcga
    12061 tttttgaaat ggcagaaatc gtcggattga aagatgtccc actaaaccaa caacagccac
    12121 ttaggttatc cacgcgagga gtaggagaac tgatacgaca attgttgcaa caaggtgttc
    12181 gacacatcat catcggcgtt ggcggaagta gtaccaacga tggcggcatc ggcatggcag
    12241 aaggtctagg ttatgctttt tacgatcaag ataatcaaaa agtagaagca ctgggagaaa
    12301 atctaggtaa aattgctaca gttgataaaa cgaacgtgcc tattgagctg attaaagcca
    12361 aaatcactgt cattactgat gttactaatc ttttatgcgg aaaagaaggc gcttcttttg
    12421 ttttcggacc acaaaaaggc ttgaaagaaa atgaattagc agtggctgac caagccatgc
    12481 atgattttta tatgagattt gcccctcaag taatcgaggc atcgggcagt agtgctggtg
    12541 gtggaatggg tgcaggactg ttagcatttg cttcagggaa aatagtctct ggcatcgact
    12601 acgtattgga tttactggag ttcgataaac gggtacagca agcagacctc gtaatcgtag
    12661 gcgaaggacg tctagatgga caaagtctaa aaggaaaagc gccagttggg attgctagaa
    12721 gagtaccaga gggcgttcct gtgatagcta tttgcggaag tgttggtaaa ggaagcgaaa
    12781 aagcagcaga tgttggcatt tcggccgttt ttccgatcct tcctgcagct gtgcctttac
    12841 aagaagcttt acagcaagcc actgataatc ttcatcgcac agctaaaaac atcgcatctt
    12901 tacttcaagt cgttcatttt caaggaggta atcgatgaaa atcaaagcag cactattcga
    12961 tttagatggc gttcttgtag acacagctcg ttatcattac gaagcgtggc tggttttagc
    13021 taaccagctg tccattccat tcactgagaa agaaaacgag caactgaaag gaatatccag
    13081 aaccgagtca ctagagcgat tgctgtcatt tggaaaaatg gaacagaaat tctcagaaaa
    13141 agagaaatca gcctttgctg agcaaaaaaa caatctatat cttcaagcga ttcaaaaaat
    13201 ggatgaaaca tccgttttgc ctggtgcaat agctgttctt gagtacttga aaaaaacaaa
    13261 catcaagatc ggattgggat cagcaagcaa aaatgcacgc ctcattttag aaaaaacgaa
    13321 tttgacaagt tattttgatg tccttattga cggcacgcaa gtatcaaaag caaaacctga
    13381 tccagaagtt tttctcaaag gagcacagca attgaatgta ccgccaaatg catgcttggt
    13441 cattgaagat tcagaagctg gttgtcaagc agctttggct ggtaacatgc atgtattggg
    13501 aataggtgaa aacataaatc ttccttctgc tgaatatgtg attcctgatt taaccgtttt
    13561 tgatcaagta cgttcgtttt ggcatttatc agaagccgta tcacgtatat aatagtttcc
    13621 gttttttctg tcacaagcaa aacgttatcc tccttttgga aatcaaggta tgatgagaaa
    13681 aaagggggat tttatatgac aaaaaaagca gttttcgcag gcggatgctt ttggtgtatg
    13741 gtcaaaccat ttgaagagca gccagggatc atttctgtga catccggtta tactggcggg
    13801 catgtaccaa atccaactta tgaacaagta acaacaggca caacagggca tacagaagca
    13861 gtagagatcg aatatgatcc agaagttatt tcttatgatc agttggtgga aatctattgg
    13921 cagcaaaccg atccgactga cgcattagga cagttcgctg atcgcggtga ttcttatcgt
    13981 ccagtgatct actataatga tgaagaagaa cgaaatattg cagagcgttc aaaacaagca
    14041 ttgcaagaca gcgggcgatt cgataagcca atcgtgacaa aaatcgaacc aagaagcgaa
    14101 ttttatcctg cagaagatta ccatcaggat tattacaaga aaaacaagct ccattacaat
    14161 ctttatcgag aaggttctgg acgtgcaggt ttccttcgtc gacattgggg cgtcaagaaa
    14221 taagaagccg aaaaagctac ttatggaaca ccgtatatca gaggttgtaa aaccagcatt
    14281 ttgagctaat actgagggtc agctgattga acaccattta gtggagaggt tgtgaacctg
    14341 tcgcctagct ccaagtcaca aggatttggt aagagaacac tatatatcag aggttgtgac
    14401 aagtcgtttg tcacaacctt ttttcaatac ctaagatgaa ggacaatcag caacgcactg
    14461 ctcaaaaaag gaatgaaagg cagcttttcc aacttttttt tatgacagat aaagtaaaca
    14521 gaaaaaacgg atattccaaa cagactagca agaaacaaga tctgaagcaa ctcttctaga
    14581 gacaagccac cactccaaga aagcatcaac agagtatcgc cagctccgag ataggattga
    14641 ccatagcgaa ggcacacacc gcctacgata aacgttaaca gcacactttg ccattggaag
    14701 acgccggcct gcaaccaaaa aatccataaa attgcccaag aacagaatag cgtgtgagaa
    14761 tggaccatga agtaaaataa atccatcaac gaaaatagca aagccgaaag catccatatg
    14821 aacgtcgaaa aatttcttgc ggaagaaaaa gtaaagaacc aggcaaaaag accaccacat
    14881 aaggcttctg ccaacaaata gtagaagggc aaccgacacc tgcaatagcg gcagcgaaat
    14941 cgttggacga tgatcgagag aatcggaatc aattcatacc aagaaagcga acgacagcat
    15001 ttgacacaat gagatctagg ataaataata gagtgaccta acggaatccg ctgggcggtt
    15061 aaacataaaa atgatccgat acagcaacca atgataaaat aaagtaacac gccatctccc
    15121 ccttttcaaa accaagatac gcaagcttaa actaaatttt tgtacataca taaaatttga
    15181 ggtgaaaaaa tgaacgtttc aatcggatta gatatcggaa ccacacaaac caaagcagtt
    15241 gctttcacag atgaagccca agaagcagca tccgcttatt ttcgctaccc tttgatccaa
    15301 gaaacacaag ggatggcaga acaagatcag gaattgatct ttcaaggtgt ctgcaccgtt
    15361 ataaaagaag taattaaaca gttgccttca gacacaatca ttcaatttgt ctccttctcc
    15421 tctgcgatgc atggcctgat attgttggat gaagagaaaa caccgttatc tcgaatgatc
    15481 acttgggcag ataaccgagc agcggacgaa gcagaaaaac tgaaatatac cgtgcttggc
    15541 aaagaatttt atcggcagac tgggacgccg attcatccaa tgacaccatt gaacaaaatc
    15601 aagtggctgc aaaacagcca acctgaatta ttcaaaaaaa ctgcttattt tgtcggtatc
    15661 aaagactata tcttttatag attgtttggc gaactgatca gcgactacgg aacagcttca
    15721 ggaactggat attttgatat ccatgaattc caatgggcag aagaagtgct tgactacttg
    15781 aacattcgaa tagagcaatt gccgcaagtc tttccttcca cctatcaagt aacaggtcta
    15841 ccatcaaaaa cagcagcaga actaggtttg ccaaatgata tatcatttgt tttgggaggg
    15901 gcagacgggc cgctttctaa tctagggtta ggtgcttttg gtgatacgat cgccgctttg
    15961 accgtaggaa cgagcggagc acttcgtttt attactactc agcctcagtt ccatccagaa
    16021 atggagacgt tttgttatgt tctggatcag aaacattggg tagtgggagg agcgactagc
    16081 aatggtgctg gcatctttga ttgggcaggg catacatttt tacaggaagt cgttcaatct
    16141 gctaaagaaa aaggagaaaa tccatatgat gcactgcttt cggctatcgc ttttgtgcca
    16201 gcgggtgcca atggtctgat ttttcatccc tatttacttg gtgagcgagc accgctttgg
    16261 gacgcagatg cgtttggcag ttttatcggt ttacagcggc aacatacaga aaaagaaatg
    16321 atgaaggcga ttctagaagg gatctgtctc aacctttatc ggattttaaa aggagtttgc
    16381 caggaaaatc agctcacaga gatccgtgct acaggcgggt ttgctcaatc tccgattttt
    16441 cgtcagatga tggctgatgt actgggttac ccgcttgttt tccctactgt cacagaagca
    16501 tccgcattag gagctgtgat tttaggctgg agaagcatcg gaaagatcca aagtatcagt
    16561 gaagcacagg aattgataga attgaaagag caagttggag tacaagaaac tgatcataaa
    16621 aaatatcaga aaatctatcc attatttgtt tcgacacaaa agcatttagc acagacttat
    16681 cagcaatttg ctcaactgcg agaagaatta gctgattctg aaaaatgatt ggctttacgg
    16741 ataaaaaagc gaactgaaaa tcgttctcag gtaaatgatt ttgttgtact tttcattgaa
    16801 agtctactat tattttaagt gtaagaaaat gttaggaggc aagaaagatg aaattccaac
    16861 aaaccaaaga agtattaaat caattagttg cagatctaag ccaaatgtct gttgttgttc
    16921 accaaacaca ttggtacatg agaggaccag gtttccttac attgcaccca atgatggatg
    16981 agttcatgga tgatttgaac gctcagttag atgaagtatc cgaacgcttg atcacattag
    17041 acggttcacc ttattctaca ttgcgtgaat ttgcagataa cacaaaaatc cctgatgaaa
    17101 ttggccgctg ggatcgtact attccagaac gtttggaaac acttgttgca ggctatcgtt
    17161 atctagcaga tctttaccaa aaaggaatcg aagtttctgg agaagaaggc gacgatccaa
    17221 cacaagatat ctttatcgaa ttcaaaacag ccacagaaaa acgtatctgg atgatccaag
    17281 ctcatttggg caaagcgcca gagatcgacg cgtaaaaact gttgttgaac ttgaccgaaa
    17341 aagaggttgt gaaatcagcg ttttgacctg agtattagag aaacaaacgt caaaatagtt
    17401 cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa caccgtttac
    17461 caagaggttg taagcctgcc gttcagctcc gagtcacaag aaacaatttt aaaaaacagc
    17521 ttcttatgtt ttatggatat tgtgacttgt gaccgaggag ttggcaggag aacaccgttt
    17581 attcaaaata aggggttgtg acaagacttt tgtcacagcc tctttttgtt tttcattttg
    17641 acaggaaacg acccttttat ataaaagaaa gaaaagaagt aaagtttcat ataaattttt
    17701 caatcaagca gaaaaacgtt gacattgact agattagcgg gtaatatgtt aaatggtatt
    17761 gtttgcccca caaagagccc cggaaactcg aagtgtatgt caaacatcag aacttaaatt
    17821 ggaggaaaat aacgtgcgta caacatatat ggccaaacca ggcgaagtag aacgtaaatg
    17881 gtatgtagta gacgcaactg atgttccatt gggacgtctt tcaacagttg ttgcatctgt
    17941 actacgtggt aaaaataaac caactttcac acctcatttg gatactggcg atttcgtcat
    18001 cgtcatc
//
LOCUS       DADGKS010000058        16894 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.058, whole genome shotgun sequence.
ACCESSION   DADGKS010000058 DADGKS010000000
VERSION     DADGKS010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16894
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.058"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(451..1761)
                     /locus_tag="JXV47_002091"
     CDS             complement(451..1761)
                     /locus_tag="JXV47_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAX1488114.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1773..3191)
                     /locus_tag="JXV47_002092"
     CDS             complement(1773..3191)
                     /locus_tag="JXV47_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAX1488115.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3431..4999)
                     /locus_tag="JXV47_002093"
     CDS             complement(3431..4999)
                     /locus_tag="JXV47_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HAX1488116.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(5003..5413)
                     /locus_tag="JXV47_002094"
     CDS             complement(5003..5413)
                     /locus_tag="JXV47_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HAX1488117.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5410..6333)
                     /locus_tag="JXV47_002095"
     CDS             complement(5410..6333)
                     /locus_tag="JXV47_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HAX1488118.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6330..7208)
                     /locus_tag="JXV47_002096"
     CDS             complement(6330..7208)
                     /locus_tag="JXV47_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAX1488119.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7195..8532)
                     /locus_tag="JXV47_002097"
     CDS             complement(7195..8532)
                     /locus_tag="JXV47_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAX1488120.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8535..9638)
                     /locus_tag="JXV47_002098"
     CDS             complement(8535..9638)
                     /locus_tag="JXV47_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAX1488121.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9712..11220)
                     /locus_tag="JXV47_002099"
     CDS             complement(9712..11220)
                     /locus_tag="JXV47_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAX1488122.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11186..11878)
                     /locus_tag="JXV47_002100"
     CDS             complement(11186..11878)
                     /locus_tag="JXV47_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAX1488123.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11900..12874)
                     /locus_tag="JXV47_002101"
     CDS             complement(11900..12874)
                     /locus_tag="JXV47_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1488124.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13174..14046
                     /locus_tag="JXV47_002102"
     CDS             13174..14046
                     /locus_tag="JXV47_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAX1488125.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14628..16826)
                     /locus_tag="JXV47_002103"
     CDS             complement(14628..16826)
                     /locus_tag="JXV47_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1488126.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLFSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
BASE COUNT         4973 a         3535 c         2740 g         5646 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcgag agtgtttccc gattcatttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt ttcgatttcg
      181 tttttcgaaa tctttcagca actcatttat cataacttat cgtttgttat ttgtcaagaa
      241 cttttttgaa gtttttttcg atagaatcaa gcttcgcaag tggttctttt taacgactta
      301 gttatcttat cacgtctaaa aacatgtgtc aactcttttt tggaattttc ataaaatgtt
      361 tcaatgaagc gcgacaacgt tgtttaatat atcattaaaa aaaataaagg tcaagctaaa
      421 atattattta agcttgacct tattataatt tcaacgattg tcaaaagtat tgtttgcagc
      481 tgtgttgcca gtttctatag ataaatcaca gcttttgaaa cataagtttt gtactgcttc
      541 gattcgcccg aattcttttg cagttatttg gcaatgagaa aagcagacat cttctatagg
      601 cttttcagga aatgctacta aatcaaaagc tcgggaagga agtgagtaac ctggagaaag
      661 gcatgcctgt acgtttttga tgtgtatgtc tttgactttc gtcatttgct ttgattcagg
      721 tatttcttca gccactgctt gccaactttc tggcatttga gcaaggtcat tgctattttt
      781 tctattgtat tcattatgcc agtccattat ccaagaaaaa ggaaattgta catcaatcat
      841 attcagattt tctaccctga tattttcgat cactccccct ctttcttttg aagatttcat
      901 tcgaatacca cagtctgact gaaaaaaatc gatatcgtga atatatacgt cactaactcc
      961 agcactaact tcgctaccaa tagttacacc gtatcctgaa cggattttac atctagcaac
     1021 ctcgattctt gatgattttc gattgactct tgcaccattg ccatctctgc cagacttaat
     1081 agcaatacaa tcatcaccac aggccaaatc acattcatag acacgcacat ttgttgaaga
     1141 atcaatatca atcccatctg tacttggtcc atcattgttg cggatgatta ctttttctac
     1201 taatacatcg ttagaataag tgatttgcaa gttccaaaaa cctgatttct gaaaaatcaa
     1261 atcacgaaca acaacatgtt ctgcatgata cagtaaacaa gcgcgtggac gtttaatagc
     1321 ataatccgca atccaacgaa gtcccttttg atcgtattca gctcttgtcc cgcttttttg
     1381 atcttttccc caatacagct cccaccaatg gtctccttga ccgtcgatta ttccttttcc
     1441 ttctataaga atatctttcg ccgagagaac attcaaaatc gctgctggcc atttcatttc
     1501 tacgccggct actcgtgtat cgatttctgg aaatgcttcg atatctgttc tccccttgag
     1561 gactgcacct tcttcaaaga taagatgact cttatctttt aaaaaaaggg ctccgactaa
     1621 ataaatgcct tttggaataa atacaggtaa gtgttctttc gcaccttgat cgattgcttt
     1681 ttgcagtatt attgtatcat cttgttgagt gtcgtttgtt ttaaagttca aagcattgat
     1741 aatccctttt tttgtccgca atacgtttct ccctatcttt cattgatttt tttcaattct
     1801 tcaccaataa atacagtttt tgaacgattc agtgggtaac ctactagcaa aatgattgcg
     1861 gatacaaata agcagaatgc tggtaacaag tttgccatcg tataaatcct ttcttgtact
     1921 aaaactgatt ggatggctcc acctgttgta gacgattggt aaccaatgag tgccagcata
     1981 aatccgccta ccgctcctgc acatgcttgt cctacttttc tcgcaaaaga atttactcca
     2041 tatactgttc catcttctct taagcctgtc ttatattgat gataatcaat cacgtcagta
     2101 atgaatgccc agaccatcaa attgaataaa ccagatccta aagtagcgat aaataaaaga
     2161 atcagatata cccatgcatt tgttatatga aggaaataca tcagcaagta catacatgaa
     2221 gaagcaagta acgcaaatac gcttgcttcc tttttaccaa ataattttgt cagctttgta
     2281 gcaaatggtg ctaaaactac tactgttccg taagtaaata aaagagcaac agacattgct
     2341 tgtttattat ggaagtaatc attgaataaa taagtcatat tcgtcccagc taaaatctga
     2401 ttgatcacaa tgaaaatgtc aacaatgact aaaataatca gtgctcgatt agctaacaaa
     2461 ccttttacca actgagaagc agatactttt tcgtttttga caactcttac tctttcagta
     2521 gtcaatttac aagttaacat atatgcgaca aatgctattg cagcacatcc gattgaaatc
     2581 caaaagaaat gattccctga aacgacttgt tgtccactct tgttatgggt atacattaaa
     2641 atcggaatga agaatcctgt agttgatccg ccaatcgcag aaccaatgct tcggaacgtg
     2701 gacaacgagg tgcggtcatt aggatttgag ctaattgctg ctgccattgc tccatacggg
     2761 atattgattg ttgagagaaa aatcccataa acaatgtatg aaacaaaaat ataagcaatc
     2821 ttcaccgtca ttggaagatg ttggacgaat ggcaaaaaca aaatgacagt cactaagcaa
     2881 aatggatact tcatttttct gatccaagga ataaatcggc cagtttctgt taactctgag
     2941 acatcacata atcttccaac catcacatca gcaaacgcat ccaaaattct cgaaatcaag
     3001 aataacgtac ctacgattgc ccctgaaacg ccaagaacat tcgtataata aatcatcaag
     3061 aaactattga ctaaacctaa aataaaacag ttacctagat caccgaacat gtagcctatc
     3121 ttatcggaaa tcccaaattc ctttttttct ttttttattg tatttgctgt aacagcattt
     3181 tgtgaaagca tttgaattcc tcctacctct tctagtaaac gttttcaaaa ttataactct
     3241 ttttttcttg tttttatatt cacaatgttg gctttttatt gcattatctt gacagataaa
     3301 aaacaaaaaa taatctaaaa acattgatgc ataagattga taactttttt tacataacaa
     3361 tatatacaaa caaaaaaatt cactaactag tgaaaataag ttagtgaacc tcatttatta
     3421 aagaattaaa ttacagatga tcttttccat catacttgaa aaactcaaaa tcagcataac
     3481 ttcctctttt tttatttaga tcatgcactg ctatcccgat aaaatttcca gtaaaccctc
     3541 ctgagagtat acacatgttt ttttgcggac ctactttctt ccattcttca gttgatacgt
     3601 ctttcaaatg aaactgtgct gtctctttct ttacagtgac tttcaaaaaa gtcttctttt
     3661 ctgtgagtgg aatcgtccaa tcttctattt gtgctactcc gttttctgat tctatcatac
     3721 gtaggcattt tcccttgtcc tcattccaag taacataaca ataaatataa ttggattcat
     3781 ttaagtacag taccagtcca gccatctgat taaaattatt aggcatgtat tcaaatgctg
     3841 tctccgcatc aaaagtaaaa tccgtttgcc gaatagctaa caaatgatgt tcgaaggtag
     3901 attgaagaga ttcaccggaa atcagacgta aaaaacctgg tctacatttt gtatcacacc
     3961 aatcagcatt tggcaaaatg cgtctggcat tccagttctt ctttagctct ccttcaaatg
     4021 tatccataaa ctgatgatct ttttcttgtt gtacctcttc atttgtctca atcattattt
     4081 cttccatcgg agttgtctgg ctatctttaa gtcttaacca atcgtcggac gtccaataca
     4141 cttcttgaat agcggtttct cttcccaaaa tagccgcacc gtttaatggt ctggtacaaa
     4201 gatatgtcat gtaccatctt cctgacgggg tttgtactaa gctcccatgt cctgtacatt
     4261 gcaatgtaga agcaggtttg tcactagctg tcagcatagg aaaaccagga tcaagctcgt
     4321 aaggaccagt aatattcttt gctcggcaaa ctgtaactga atgtcctctt cctgtaccgc
     4381 cttctgccgt catcaaataa taatacccgt tacgaaaata caaatgtggt gcctccgttt
     4441 tcgctaattc tgtacctgca aatattttat agatgggacc atcaagcttc ttcttctctg
     4501 catcatattc ttgtaatacg ataccgctgg atttattcgg tgtgtccaga cgataatccc
     4561 atagttcatt gacaagccat ttttttcccg tttcaagatc atggaacaaa gaaggatcaa
     4621 agccgttact atttaaataa attggttcgg accaaggacc tgtgatctca gatgcagtga
     4681 tcaaataatt gtggacatct ttaaacggac ggcctgcact tttgacatct gtgtaaacaa
     4741 gataaaacaa tccatcagca taactgattt gtggcgccca tatacttcca tttgtaggat
     4801 ttccttgcaa agatacttga gtggtcaaaa tatccgttgt atgtgaccag ttgactaaat
     4861 ttttcgactc atatactcgg attcctggaa gccattcaaa agaggagaca ataatgtaat
     4921 accgctcttt cactcttaat atattaggat ctggattgaa tcctcttaaa ataggatttt
     4981 tcactttgat agtctgcatg attcaggctc cttttctcat tcttactcga tataaactga
     5041 atgccccagc tgcgaaataa aaaaatgcaa aaggaaacgc aataaactga gtgccaatca
     5101 acaatatgaa tcctgttata aaatacaaac cagtggcagt tgttaagtat tttcctttag
     5161 cagtcaaaaa caatgctact gctaaaaaag caagtgaaat aaacaacaca acggcaaaca
     5221 gaccagtcat gtcctgtaat aatccaaatg tattttctaa agacaaagtt gaatgatcta
     5281 cagcaagcga ctgataactt tttttaaact ctgacgcaga catattactt aaagtaactg
     5341 ctaacccgcc aaagaaaatc aaagatagac tgccaccgac cattcctagc aatagttccc
     5401 attttctttt catttctgaa ccccctgctt ttctaaatgt atccattcag gtcttttgat
     5461 cgatgtttca taattgttat tacgttcaga gaatttgaca gtctgttcat ttttcttgtc
     5521 atcccaatta tcccaaccag ttgggtgaac atgcccacct atcttacacg cttcaaataa
     5581 gacatttgca tacggacgcc acggtcttcc taaatagacg tttctagtat caggttctgc
     5641 agtcaaggta cagctttcaa aacgataccc tgttttttga tttttcggcg tagatgctgc
     5701 tgtgatgtat ccaggatttt tactggctaa gctatggata tgacactgat gaaaaacggc
     5761 atctgcccca ccaaatatga aatccaccgt tccttcaatc cagcaatatt cataggtctg
     5821 acgacaatac tcaggattgg cagaagccgg tgtacaaaaa ggagtaccat ctttttgcaa
     5881 atcaggcaac ggacccgtgc ataaggtatc ctgataacca gatagtcgac agttttttaa
     5941 agatacgcga tctcctgaat tgaataaagc aacagcctgt cctacctttt ctcctggacc
     6001 tgctgtattt tcgatgtgaa gattttctaa tacgacattc gatccttcta agaaaaaagt
     6061 agcacttcgg aaagtcccta actggctacc gtcaagatac tcctgttttg caaaacgatt
     6121 accggagata actactgttc ctgctcccac aagtttaaaa ttggataatc tgctttctat
     6181 atattcatca tatcttcctt cttttactat caagaccttt ggatggctat ccggcaggcc
     6241 tgccaaataa tcgattcctt cttggatagt ttcaaaatcc gtcggggtat ctatagcatt
     6301 ctttccaatt atcagtttgt ctttcatcct cataaatgct cccttatgaa ttgtttccaa
     6361 atatttctca tttcttgtgt ttccatatga ccgcctgtta aagaaaaaga agaaaagttt
     6421 tctggactac ccattgattg atactttttg tccagccctt ttctcagctt cagtacgcct
     6481 tcgtccaagc acatcgtatc gttttttcca actaagctaa gacgagggcg cggagcgatt
     6541 ttttcttgga ttgctaacgt tgtataagct gtcaatagat ttggcacata gtaataaaac
     6601 ccatgatgat ctaggcggcg atgtagcaaa agtatttcga tgtccacctg tgccgctaga
     6661 tcaatacaaa ctttgacacg agaatccaat gctgtcaccc accagcttaa taagcctccc
     6721 atagaaagac caatcgttgc gagccgttga gtatctgtgt cttcccttgt ctccaaataa
     6781 tcgatcaagc tgatcacatc ataaatacgc attccccata acgtttttcc tgttaataaa
     6841 aattgtttga acaactcgct ttcagaaata cctccgcgtt cttcaaatcc ccaagcatca
     6901 atcgaccaaa cagcatatcc cattcctgtc agtacttctg caaaagatgg agaagctaag
     6961 taaggagcac catggatcaa ttcacttttc ccgactgaaa aatctccgcc gtgagaatgc
     7021 aggtaaagga ccggcggaaa cggtccttct ttttctggat aagcatagag ggctggtact
     7081 gtttccaatt catttaagta caattgatag tattcaagca taaaaccgtt ttgtttttct
     7141 cggtataatc gttttccact aggggtatgt ctgctagatg gagcacctaa aaaatcattc
     7201 aactgcataa gcaaagtttt tacgaacaac cagttcatcc atattttctg attgatttga
     7261 ttggaatttc tcaatactga tttctttagt attttctaat agaaatgctg gtccctcgtg
     7321 attttcaatc gacatctggt taaaggaaac cttacccgca aagccaatat aaaatccttg
     7381 tctgctcatt tcctctattc ctgtcatcat agcaggaaca ccgggaactg catcttgggc
     7441 catcgagaca tcgatattgt caaatgtgat ttcttgtatg aattgttccg ctaatccata
     7501 aataaaacct gcagaagcat ggacattcct tgccgtgata ttcgaaaaat ggatccttct
     7561 gaatgctggt gtccgttcat ctatcggata agcctttttt tcccatacat acggttcttt
     7621 ccctcgcgga ccacagaaat aataaagatt cagtataaat ggacacatca cattatccat
     7681 gactatattg gatactcgaa tatcttcaac gatcccgcct cgacctcgtc tagatttcaa
     7741 tcgtattcct cgatcagttt cttggaagat acaatttgaa atggtaatat tacgaatact
     7801 accactcatt tcacttccta atacgacacc gccatgtcca tggaccatcg tgcaatttgt
     7861 gatcgtgata ttttcgcaag cgatcctttc gtacgtatct tcagtccctg ccttgattgc
     7921 aatacagtca tctcccacgt caatatggca attactaata cgcacatttt tgcatgattc
     7981 tggatcaatt ccgtctgtat ttggtgaatc cgctgggttc aagatcgtca agttatcaaa
     8041 cgttgcatta ctgcaaagaa tcgggttgat cgtccaactt ggtgactgga tcaatttaat
     8101 atctttcaca gtaattcgat gacagttatg gaaactcatc aatttaggac gaggataagc
     8161 gagattatct ggttcatttc taaaagtatg ccaccatttt tttccatttc catctaatgt
     8221 accgaaacca gtgacagaga tgttctctac attttgagca tagatacagg aagcataaac
     8281 ttttcgatgg actccttccc aacgtgaatg aacaacagga taatcttttg gatcgtcaga
     8341 gaatttcaga accgctcctg cgcttaaatg aagttcgaca ttgcttttta aaaataaagc
     8401 tcctgttaga aattcacctg ctggaacaac tacggtcccg cctccgtcac ttgctgcagc
     8461 atcaatggct tgttgtattg cttcagtatt caattcatca attgatgcgc caaatgtcaa
     8521 aatatcatac atatttataa tgcctccact tcaatcaatg cttgcaagaa tgcaccaacg
     8581 cctttttgat cattacaaat aattggttca ctgatgtagt aagcatatga accatctcgc
     8641 tgatctgctc cgcctaaccc tgctacttga cagtttttat tcaagttcag ccagccttct
     8701 tttgtttcca gaacaaattc atcaagtaat ccttgatgtg atttcttcac ttgtggaagc
     8761 cattcttctt tgttcagcag tcccaaacgt attcctttag ccattgcgta aacaaacata
     8821 ctactgccgg aagcttccag ataatttcct ttccgttttg tttctgttgt tacttgatac
     8881 catgtcccgc tgttttcttc ttgatatgga agtaatgcag ccagtgtctt ttctagaatt
     8941 tctttcagca aagaacaatc tgtttcttca tgaagtaatt cataggtatc tgctgcagcc
     9001 atcaaatacc agccaatcga tcggctccaa aaatgatggg atagacctgt ttttggatca
     9061 gcccatggtt ggaccttctt ttcatcccat gcatgaatca gcaaatttgt ttttggatcg
     9121 aatagatgtt tataactgat ttcaaactgt ctcaaaacat cttggtaatc tttttcttca
     9181 ctaaaattct ggataaattc agcataaaaa ggagaaccca tatataagcc atccaaccaa
     9241 atttgataag gataaatttc tttatgccaa aaagctcctt cggatgtgcg tggatggttt
     9301 gccaactgct gggaaaggag ttctgctgct tttttatatt tttcttcgcc tgtttctttg
     9361 tacaataaaa agaaaagctt tcctgtattt acatggtcga tattgtattc ttcaacgctg
     9421 tagccacgga tcgttccatc ttcttgcacg aaatagtcga tattgtcttt tatgaaatca
     9481 aaataaattt tttcttgggt tcgttcccaa agtaattgga accctttaag tacgacgcca
     9541 tagtcataag accattttcc tttataccac ttttcttcat ataagcgagg tgttctttcc
     9601 atgatacttt ttgctaattt ctttgaccag ttttccatta tttgctctcc tttaaaaatt
     9661 aaaataggat ttgggacaaa taccaagaag tatttgtccc aatcgtctat attactgtgc
     9721 cgctgctttg tatgcttcct cgtactcttg tgtgattcga tcgcctcctt gtgctttcca
     9781 gtcttctaca gcttttttga atccatcttc gtcaagctgt cccatgatgt attgcaccgt
     9841 agcatcaatg acgatttttt caatttctga tcctacttca ttgttcgtcg gtgaatccaa
     9901 tggcacagaa ggatccatta cagcaaattc ttcattttct ttgatcaatt gattagagaa
     9961 ttctttttca gggtctgtat ctttgaaaga gaacgtcact tcactaggac gagagcttga
    10021 taacggttgc acctcttgtt gccaaagatc catatcgata aattcgatag aaccatcatc
    10081 attcaattca taatgcgttc cttcgatacc gccagtcatc aatttataca catcttcttc
    10141 taaaagatca tcaacaaatt gaagtaattt cttcaattgt gcttcgtctt ttacttgaga
    10201 tttgggaaat gctagcaagc cgccaatacc atttccttct gaccaaacat gataaccgcc
    10261 gccttcacca tctgagatct tgtttacagg cactaattcc atatcatctt gaataccttg
    10321 acccatcgtc ttcagattct tgatatccac cattccagtg tagattccag ttcttccttg
    10381 tgcaaattgt tcttgctgat cagtcttttg ggtaactgca aagtcttgtg ccaaatagcc
    10441 attctcaaat agatctcttg aaaaattcaa agctttcata tactcttctg tatcaaattc
    10501 tggagtgaat ttgccattat cgtctacagc ccagccattt ggtgctccaa aataagaagt
    10561 gaaaagttta aagctggtat aacgaatatc actaggcgca cgatcgccaa aaccaactgt
    10621 gtcgtccaca ccatttccat caggatcgtt ttctgtaaat tgtttagcta cttcataaag
    10681 ctcatccatg gtagttggaa catctagtcc tagattatcc aaccagtctt ttcgaatgac
    10741 taagccagca cgagcgtagt ctttttgtat cggtacgccg tacaaggcac cgtcgatact
    10801 cgcagcttcg attctatctt cagaaatttg acttaaattt ttatagtctt ttaaatattc
    10861 tgatacatcc cagaatacgc ctgattttaa cgcattgcgg acagaagagt ttttcaacat
    10921 cgcaatttga agtgtaacga tatctcctag ttcatcagaa gccaatgcag ttgttaatct
    10981 ttcttctttt gaagcatcag gaatccagtt gaatgtcagt tccgtatcgg ttttttcttc
    11041 gatcaagttc acaatcgtgt ctgtaggcgg tgaagcatga tgcaaaatat ttaaccaagt
    11101 gattttagct tttccatctt ctgtctctga agaactgtta cttgaactgc tgccgcatgc
    11161 ggcaagtgct agaattcctg caaaactaag acctaatttt acgagcgttg cttttttcat
    11221 aaattttctc cttcactgtt ttaataatat ttttgttttc ttctgttttt tctgtatatg
    11281 agttcttcca ttccaaatgg caaaatatag aatttgctgt ccacgtgact gcggaaaaga
    11341 agagactgcc accgataaag gttaaaacac ctggcattgt ttggatgatc atcagataaa
    11401 tccctaccat acttaatatc aacactaatg agtaatgaag atgtgagaat ccgaataaaa
    11461 atgccatttt cattttgaaa aaatatcctt tccaatcata atgagccatg attgggaaaa
    11521 tatagagtgc tgagagcaca tatatgaacg cagcaatata caaagcgatc ctaagatacc
    11581 aattgtgtat gaaagaaaga tccacaagta aaacaatccc gatggcgcca tatatccagc
    11641 tcatcagcaa ggtttcacga tagttttctt taaaatatgt gaagtacgtt ttcgtcaaag
    11701 gaaacgtttc ttttgagcgc agccattttc taatcactgc aaccatcgca tacgatgcag
    11761 gaccgaaagt aaaaactccc aaacctgcga tgactaaacc gccccacaga aaattcaaat
    11821 aaaccaactg taaaatacga tttagccttc cgtttatttt atctaatgac tgcagcatat
    11881 ctttccctct ctttctatct tagtaaacgc cgtcttctcc tagctttttg gcaatcttat
    11941 tagctaaaat taccataaac aatcctacga cccctttaaa caatcccatt gctgtactga
    12001 aacttaactg tccattcttc aatccagctg tataaatata ggtgtcgaaa atttctgcaa
    12061 cgcttcgatt caatgaattc aataacaagt acatatgctc gaaccctaag tctaatgtct
    12121 gaccgatttt tagaatcagc aaggtaatga ttactggacg aattgccggc aatgtaacat
    12181 gccatgtttt gcgtaagcgt cctgctccat ccatttctgc agcttcatac aactgtgtat
    12241 cgactgcagt tatcgctgaa aggtagatga tcgtagacca gcccaactct ttccagatca
    12301 cttgtccgat atatactgtg cgtgtccatt caggggatgt tagaaaactg attttttcaa
    12361 atcccattgt tgcaaggaat tcattcaata cccctccgtc aacattcaaa aatacataag
    12421 taatcgaaac aatgattacc caagacatga agtgagggat gtaaatgatc gtttgaatcc
    12481 cgtttttcaa tcgtttgttc gttacttcat ttaatagtaa agacaaaatg attggcatcg
    12541 gaaaaaacac gaagatattt aatccgaaca agatcaacgt atttcttaat aatgtaaaga
    12601 atgtcggttc tgtaaacaaa cgaatgaaat gtttgaaacc gacccaagga cttcccatta
    12661 ttcctaaaaa tggttgataa tcttgaaaag caataacgag tccccccata ggaagatacc
    12721 taaaaatcaa gaaataaagg actcccggca gaatcatcac atataaaaat ttattcgttt
    12781 tgattcctgc aattattttt tttcgtcttc tgagcttttc ttcttttttc gatagcgtca
    12841 gttgaaatgg ttcttgtttc tttacacttt ccataagccc ctccttagtt ttgtgaatgt
    12901 ttgctgctta tgacttcatg atagataact atctgaatta cgtatataat catttttacc
    12961 gtaagtaaaa acgcttacat agcaatgatt tttgtgctat acaaaacgat aaagtgtatt
    13021 ttttcacaaa taaactacgc atagcaaacc ttctattttt ttctatctga cacttagcat
    13081 aggaaatgat tatatacgta atctttcacc gatgataaat tgaacatata gaaacagaaa
    13141 catttaattt attttgagga ggagcctatc tatatgaaaa agaaagtctc tataggagaa
    13201 agaagtttta cacttttcaa caatacgttt ctaattttgc tagctttgat ctgtatcgtt
    13261 ccttttttaa atatcatcgc tacatctttt gcttctacac aagaagtcgt cgcgaaaaag
    13321 tttatccttt ttcctactac cttttcttta gacgcgtatc gctacattct ttctacgccg
    13381 accattttta gagcacttgc tgtttcgatt ggtgttacag gtgtcggaac gatcgtcagt
    13441 atgtgtgcaa cttcactgat ggcctacggt ctttccagaa agtatttgtt tggtcgaggt
    13501 ttcgtcaact ttcttgttgt attttctatg ttgttcagcg gggggatgat tccaacgttc
    13561 ttagttgttc gttctctagg gctggtcaat tcttactggg ccatgatcct gcctgtggct
    13621 gttaatgcaa tgaatatgat cattatgaga aactttttcc aagccttgcc ggatagtttg
    13681 gaagaatcag caaaaatgga tggttgcaca gattttggtg tatttttcaa aattatgctg
    13741 ccattagctt taccgtctat tgctactatc tcgctttttt atgctgttac ttactggaac
    13801 acttatatga ctgctatttt gtatatcaac gattcatcta aatggccgat acagattctt
    13861 ttacgccaaa tcgtcattgt atcaagtggg atgcaagcag aaagtagtgc cgttgatgtg
    13921 attccaccag cacaaacagt taaaatggct gttatcgtta ttgcaacagt gcctatgctg
    13981 attgtttatc cttttgttca gaaatatttt gtcaaaggag cactcgtagg ttctgtcaaa
    14041 gggtgattat gtactgaacg caaaatggta gttgtgtcag aagtggtcag cttcaagaaa
    14101 taagaaggca tttacgaaaa ttgcttctta aatttttgtg aaatttcggc ttatttttcg
    14161 aagaatctac tcctggaaca ccgtgtatca gaggttgtga aagagacgtt cagccttgag
    14221 cgatgataaa aactctcaca aacattgcga cgagtaaccc acaggagcaa taagaagcga
    14281 ttttgaaaaa tagcttccca tatttcacaa aattatgcct tattgtcgat agcctgtctc
    14341 ttgaacgcca tttattcgta aaaaagaact gtgacaagac ttttgtcaca gttctttttg
    14401 cgtgcttagc cttgaaattt aactatccat aaatacaaat actagggtta ttctaacttc
    14461 ttttattgct tgaatcagtc cacaagaaaa acagcctctt gattaaacgg cgtttatctt
    14521 gttgattctg cggcaataaa atcagccagc agcaaaacat gaagtgctgt tttttgctgt
    14581 cctcttttat tgcttgaatc agatcacaag aaaaacagcc tcttgattca caaatatttt
    14641 tttcgatatt ctcccggcgt aatcgattcc ttctttttaa agaaacgaat aaaattttgc
    14701 ggatttcgat attgcaatct ttctgcaatc tcttttacgg agaggttagt ctctttcaac
    14761 catttttttg ctacctctaa acgatgattt tgaacaaaat caccaaattt ttctcctgtt
    14821 tcctttttaa atacattact taaatagtta gggttataat gcaacctatc agcgatcaca
    14881 tctaaagaca gatcacgatc atattctgtg tagacgatat gcataatatt ctccgacaaa
    14941 tttttaaatt catgatcagt gattgcttga gagcattctg tgattggcag aactaattgt
    15001 tctaaaacaa gtttttctag ttctttggga tgataattgt tcagtgcttt tacataaatt
    15061 tgtttcatgt tatcaaagtt ttttgaatct actcccaata actgtcctaa ttgaacgagt
    15121 tcattgatca agcggaccga aactacttcc cgactcaaag gatttttatt ttgtgcaaac
    15181 aatgcatcaa tcaattcatg tactaaattc ttcacttcct gatttccaga acgaatggct
    15241 tcaaacaatc gattttgttc ttctatcgga tatctaataa gtgttttttc atgagcagca
    15301 ggaacgattt cctgataaaa aataattgaa cttggaccag tatttacacg ataatacagg
    15361 gcttcttttg cccgatcaac cgattgcttg ctttcattca gcgtttcgaa ccggttactg
    15421 atgcctatac tgatagttaa attcaagtat tcttttacac gtttttgaat gagtcggcaa
    15481 tactccatga cttttttgct tgcttctgca tcatctttat ccattcgata aatagtggct
    15541 tgcatttctt cattcaaaac gatcggcagc attcgatttt cctttggcac aatttccgtg
    15601 atcatgttgt tgatcgctaa aagtagcaaa tcacgctccc caccgtgact atcttctaac
    15661 agatcgattt gaaccaaagc tgtataatag cagtcatttt gagaactata accaaattgc
    15721 tgcaaccgct gatctagttc tcgcctttct actcgatttc taaataaact aagtacaaat
    15781 agcgtttcca gctgtggctt ttgggtaact aagtgtgcac ttaacgcttc tttttctcct
    15841 atgatccgac tgactgattg agcgaccaaa tctagttctt tcccactgaa tccttttgat
    15901 ttaagattca gacgttcctg tatttgagaa atcggacggg caaatctgtc cgaaaataag
    15961 taggaaaaaa gaccaatgag tcctaccagt gttaaagaca ctgcaactag cccgattctc
    16021 agattgcgga tcattgcgcc aattgcacta gagtcaactt ctaatctgta aatccaatta
    16081 ttataatctg atttcagtac tatatacgtt ttatcttttt ctcttatcac tttcagctga
    16141 ttgtaatcta gatccacgtc cgttaataca gttggttgct ctttattttt tactgtctga
    16201 gtagtaaaaa ggttgccaac ttcgttttca atagaaagta tgtcttctcc actttcacca
    16261 acaacttgtt ctattgtatg tttctctatc gtagcaattc ccaatgcata tttttctttt
    16321 tcaaacattg gcaaagaaat caccatttcg attcctttgt ttttcttttg ccaaaataaa
    16381 ttatttttgt tatttatgta cttctgttga tacttttcaa cttcctcttc ggtcagttga
    16441 ctcaacgatc cattgattac tccccattta ccagccaaac tgactaaatc ataattatta
    16501 tcatccataa caatcgtttc tataaaattt agttctttcc tgatttcaga ataagtggag
    16561 taatctgtat atgtcagcgg atgcttgaat atgtccgaga aatttttggt cgaaccatac
    16621 gtagaaaacg aatattcaat cgttctaatt ttccattcaa cgttagtttt aacttgcctg
    16681 agcaaattct ttttgtctgt taaataactc gattcgatcg attcataggt attctggtaa
    16741 atgaataaac taaatcctat gacaagtacg gctcctaata aaaacatcgg taaaaatatt
    16801 ttataaaata ctgtactttt cttcattttc ttcctctcct ccttttaaaa taaaaggctt
    16861 tcatttttct gtaaaattga tactcatcta atta
//
LOCUS       DADGKS010000059        16065 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.059, whole genome shotgun sequence.
ACCESSION   DADGKS010000059 DADGKS010000000
VERSION     DADGKS010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16065
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.059"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            49..164
                     /gene="rrf"
                     /locus_tag="JXV47_002104"
     rRNA            49..164
                     /gene="rrf"
                     /locus_tag="JXV47_002104"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(217..687)
                     /locus_tag="JXV47_002105"
     CDS             complement(217..687)
                     /locus_tag="JXV47_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HAX1488127.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(846..1304)
                     /locus_tag="JXV47_002106"
     CDS             complement(846..1304)
                     /locus_tag="JXV47_002106"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HAX1488128.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1475..2620)
                     /locus_tag="JXV47_002107"
     CDS             complement(1475..2620)
                     /locus_tag="JXV47_002107"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HAX1488129.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2633..3550)
                     /locus_tag="JXV47_002108"
     CDS             complement(2633..3550)
                     /locus_tag="JXV47_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HAX1488130.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3978..4541
                     /gene="efp"
                     /locus_tag="JXV47_002109"
     CDS             3978..4541
                     /gene="efp"
                     /locus_tag="JXV47_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HAX1488131.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            5027..6286
                     /gene="lysA"
                     /locus_tag="JXV47_002110"
     CDS             5027..6286
                     /gene="lysA"
                     /locus_tag="JXV47_002110"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HAX1488132.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            6273..7073
                     /gene="dapF"
                     /locus_tag="JXV47_002111"
     CDS             6273..7073
                     /gene="dapF"
                     /locus_tag="JXV47_002111"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HAX1488133.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            7076..7957
                     /locus_tag="JXV47_002112"
     CDS             7076..7957
                     /locus_tag="JXV47_002112"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HAX1488134.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            7954..8670
                     /locus_tag="JXV47_002113"
     CDS             7954..8670
                     /locus_tag="JXV47_002113"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HAX1488135.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            8676..9371
                     /gene="dapD"
                     /locus_tag="JXV47_002114"
     CDS             8676..9371
                     /gene="dapD"
                     /locus_tag="JXV47_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HAX1488136.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            9387..10388
                     /locus_tag="JXV47_002115"
     CDS             9387..10388
                     /locus_tag="JXV47_002115"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HAX1488137.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            10385..11746
                     /locus_tag="JXV47_002116"
     CDS             10385..11746
                     /locus_tag="JXV47_002116"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HAX1488138.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            11706..12857
                     /locus_tag="JXV47_002117"
     CDS             11706..12857
                     /locus_tag="JXV47_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAX1488139.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            12832..14001
                     /locus_tag="JXV47_002118"
     CDS             12832..14001
                     /locus_tag="JXV47_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAX1488140.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            14176..15555
                     /locus_tag="JXV47_002119"
     CDS             14176..15555
                     /locus_tag="JXV47_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAX1488141.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            15836..16065
                     /locus_tag="JXV47_002120"
                     /pseudo
     CDS             15836..16065
                     /locus_tag="JXV47_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5252 a         2838 c         3427 g         4548 t
ORIGIN      
        1 tccagttttg agtgaacaaa atttactcaa taaaagataa caccacagtg tggtggcgat
       61 agcgagaagg atacacctgt aaccatgccg aacacagaag ttaagcttct tagcgccgat
      121 tgtagtgagg ggttgcccct tgtgagagta ggacgtcgcc acgcaaaggc aaaaagatga
      181 actagaaata gttcatcttt ttttattttt attaagttaa agaacggatt caattgcagc
      241 ggtcattttc aatggagaag tttgtggtgc aaatcgttcg attactttgc catttctatc
      301 aatcaaaaat ttagtaaaat tccattttat tgctttagtg acagtaccag gagcttcatt
      361 tttaagataa gtaaaaagag gatctgtatt ttctccattt acgtcaatca attgatgcat
      421 agggaaggta acgccataag tggttttaca agcttctgct gcttcagtcg ctgaatctag
      481 ctcttgttta aattgattgg aaggaaagcc taagataacc agaccttgtg tctgataagc
      541 ttggtaaagt tcttctaatt gtttaaattg aggtgctaga ccgcattttg ttgcagtgtt
      601 aacaatgatt atcggtttgc ctgcatattt tttcaatgaa tagacagtgc cgtcttctaa
      661 agtagtttca aaattataaa tagacataaa gttttctcct ttctatttta tataataaaa
      721 agagcgctaa actgaaaact agctatttgt tttcccgttt agaactcttt tcagacaata
      781 aatatttaat aaaatacgaa gataagatag ctatattgct tctcatcttt acgttctttt
      841 agaaactatg cttctacttc agaccattca tcgcgttttg ctaaaaattc acgagccaaa
      901 gcttgtgcac cttctagtgt atggctggca gcccagccac attgtgtttc attgcttgca
      961 ggtacttcag tagcttcaag aacatctttc attgttgctt caagaacatc taaaatgtct
     1021 tcgtagcttt catgattcaa tacagtcaag taaaagcctg tttggcatcc cattggagac
     1081 cagtctacga tgtaatctgc gtgattgcgg attagttcgg cagtcaagtg ctcaagtgaa
     1141 tgtagacttg gcatgtccat gtgttcttta tttggttgtt taaagcggac gtcgtattta
     1201 atgatgacat cgccatgcgc acccgttttt cgatcagcta cacgtacata aggtgctttg
     1261 acttttgtat ggtcaagatt aaaactttcg acattcattc tcatttgtaa gactcctatc
     1321 tgtttgttca ttcgttttga tgcttttcac taaagaatta tttagtgaaa tttacaaaaa
     1381 cgtctttcta cttgattcta acacttatcg tttccaaggt gtagcaatct gaaatatttt
     1441 ttagattttt ctgctaagtc gtttattggg acttctagtt cttgattctg tcaaatgcct
     1501 gagctaaatc gtttatgaga tcctgaccat actcaattcc tacagaaaga cggatcaagc
     1561 cgtcctttat gccagcctct tctcgttttt cttttggaat agacgcatga gtcatgacag
     1621 aaggaatttc cactaaactt tctacgccac ctaaactttc tgctaaagta aatagttgga
     1681 gtgattcaac aaatggaata gcagattctt cattttttaa agtaaaagaa atcattccgc
     1741 taaagccgct catctgctgc ttagcaactc catggagttc atgatcgggt aatcctggat
     1801 agtagacctt ttctactgct ggatgagaaa atagaaaatc agctaccaca aaagcatttt
     1861 tttgatgttc ctccatacga acacttagtg tcttgattcc gcgctgaagt aaccagctat
     1921 cttggggacc aagtacggct ccgatagcat tttggtaaaa tccgatctga tcggctagat
     1981 ctttatggtt agaagtcact aaaccagcta ctacatcgct gtgtccgcct agatatttgg
     2041 taccgctatg gacaacgata tcagaaccga gatctaaagg tctttgaaaa taaggagtag
     2101 caaatgtatt gtcagcaata actatcaatc catgttgatg agccagagtg gcactttttt
     2161 ctaaatcagt aatctttaga agcggattgc taggtgtttc aagataaagt gcttttgtat
     2221 tgggtttgat ggattgttct attttatcaa gattactcgt atctatgatc gtgtactcga
     2281 gaccattttt agtaagaact ttgtcaaata gacggaatgt tcctccatag acatcatctc
     2341 ctaataagat atgatcgcca gcttgaaaaa gagaaaaaac ggcatgaatc ccagaaagac
     2401 cagaagaaaa agcgaatcct cgaacaccgc cttccaaatc agcaatcagt tcttccaatg
     2461 caaaacgagt aggattacca gatcttgaat attcatattg tttaggctgg ccgacgccat
     2521 cttgccgata agtggatgtt tgataaatag gtacactgac agctcctgtt gtgggatctt
     2581 cactgatgcc tccgtggatc aattttgttt gaatgtgcat gtttctttcc tcctataagt
     2641 aaatgttttt tgataaatag cggtctgctg cgtctggaaa aatcgtaacg acacgatgac
     2701 caggtggtaa acgacgaatt tctcttaatg ctgctgcaaa agccgcacca ctcgaacttc
     2761 caactaatag tccttgttct cgtgctaact gcctagtata gttaaaccct tctacatcag
     2821 agattgtctc gatctgattg attgaaaggg gagaaagaaa cggcggaatg aattctacac
     2881 cgataccctc aatttcgtga ggggctggat caccaccatt taacacagag ccctctggtt
     2941 ctacaccgat tattcgaatg tcgggatatt tttctttcaa aaaggtagaa gttccagcaa
     3001 aggttccacc actcccaatt cctgctacaa aactatggat attttctttg atttcatgaa
     3061 agatttctgg ccctaacgta tgatagtaag cagcaggatt atctttattt tcaaattgaa
     3121 gaggcagata gctgtttgat atctcctctg caagtttttt acttttgctg atggcaccga
     3181 tgattccttg ctcactagga gaatggatga tctttgctcc caatgctttc atcaattgtt
     3241 gtttttctaa gctaaacttc tctggaacaa caaaaaccgt tcttaatttg tatgtgagtg
     3301 cggccagagc gatcccaatt cctgtatttc cggcagttgg ttcgatgatc gtcgtttttt
     3361 cattgatttt tccttgggca aatccttctt tgatcaaata actgcccaat ctatctttga
     3421 tacttcctcc aggatttaaa tattctagtt ttgcataaat agcagaacct ttaggcatag
     3481 aatagtgctg attgtcaaag cgataaagcg gtgtggaacc aatagcttct gtaattgtcg
     3541 agataatcat gtgggcctcc taaaaaaaga taataaaaaa aggagctgac tattaaatca
     3601 gctccttgaa agacatagag aaaaattgag tagataaaaa gataagttac ctggtactca
     3661 ttctatgaag ggcaattaat agacatgaca aatagtatgc tgcttttatg caccatacaa
     3721 cagcaacgat tcaattgttt ttggttgctg actgtcatgt gtatccctcc aagtaaaatt
     3781 tttattaacg atagcatgaa aaaaaataaa agtcaaaggc ttgaaagaaa aaaatatttc
     3841 gatagcatcg tttacccgtg tttatttttc tgacaaatag gcatgagacc ttaaaagata
     3901 gagaatactc tagttttctg gccggttgtc tgatacaata aagttgatta tgataaagaa
     3961 aagaaggagc aaaaataatg atctcagcaa gtgatttaag agccggtatg actttcgtac
     4021 aagacggcaa actgattaaa gttctggatg caagccacca taaacctggt aaaggaaata
     4081 cagttatgcg tatgaaactg aaagatgtcc gttcaggtgc aacatacgac acaacgttca
     4141 gaccagaaga aaaatttgaa aaagcacata tcgacacaaa acctgtacaa tatttgtaca
     4201 cgatggatga tacagctttc ttcatggatt tggaaacata tgagcaatat gaaattcctg
     4261 tagaaacagt agaagaagaa atgaaatata tcctagaaaa catggaagta aaaatccaat
     4321 ttttcggtag cgaagtcatc ggcgttcaat taccaacaac tgtcgtatta cgtgttgtgg
     4381 aaacacaacc ttccatcaaa ggtgcaacag tcactggttc aggtaagcca gcgacaatgg
     4441 aaactggctt agtagtcaat gttcctgact tcatcgaaac agatgaattg ttggaaatca
     4501 atacagcaga aggttcttat gtaaaacgtg cgtcaaaata attcgctaac ggattgataa
     4561 gaatttgaaa acagagcttg acctcttgaa aggcagatca tcggatctgc ctttcaagag
     4621 gttttttgtg gaatcagcaa attgaaaaat aaaaaagtat ttgattttat ttatattttg
     4681 aaagatgaat ggcaaaagct agagaaagaa aaaactgcac ttatttatga agaaattgaa
     4741 atgattcata aaattgaaaa tatccgaact attccgaact atattgaagc gaaaatattt
     4801 tttcatcact aaatagtgtt gaatttatgt ttttatgtat aaatagcttc taatagttcg
     4861 ggtattttgt ttttataacc atttttattc ttatttttaa aaaaatattt cgaaatatac
     4921 tagacaattc agaaaatttt gtttaatatt attccaataa aattcaaatc tttatcaaat
     4981 gaaattccaa taaaaacgga aaaaaagtga aaagaggaat gaaaaaatga cagaattgat
     5041 aattggcgga gtcacagcaa gcacattggc agaaaagtat aagacacctc tgtatgtgta
     5101 tgatgaagaa aagatgagac aaacgatgct gtcattcaag cgaggctttg tatcgaaacg
     5161 ttttgataca aaagtgcttt acgcctctaa agcattccaa acgattgaga tgctgcattt
     5221 agttcgtgaa tatggattcg ggctagatgt tgtcagtggt ggggaaatct ataccgcttt
     5281 gcaagctgat tttcctagag atactatcta cttccatggt aacaacaaga cgccagagga
     5341 actgatctat gcacttgaaa atgatttgtt gcatattgtt gccgataatt tgatggaagt
     5401 tgaattatta gcagaattaa gccaacgcta tttaaaaaaa atctgtatca tgcttcggtt
     5461 gaatgtcgga gtagaagcac atactcatga atatatcgtc actgcgcata ttgattcaaa
     5521 attcggcatg agctatgaaa gtaaagagtg ccaacaagcc cttcagttga taaaagaaag
     5581 cagctatcta gagttagaag gatttcatgc tcatatcggg tcacaaattt ttgatgttac
     5641 tgcttggtta gctgaaatcg acaaattgac gaattactta accgattttg accaacctct
     5701 ttccttgaat cttggcggag ggtttgggat tcgttataca caaaatgatc agccgatccc
     5761 agtcgaagag gcactaaaaa aactgattga atatacggaa gaagctttgg aaaaacgaaa
     5821 actgaccatt cgtcaattac tgatcgaacc gggtagaagt attgttggag aagctggtac
     5881 aacactatac acgattggtt tcatcaaaaa gacaccacat aaaaaatatt actttgtaga
     5941 tggcgggatg acagataata tccgtccagc tctgtatcag gcagaatacg attgtgattt
     6001 agcagcaaaa ctgtcggaag aaaaaacaga gaaagtgacg attgcaggaa aaatgtgtga
     6061 atcaggcgat gtggtaatta aagaagctta tttgccgaaa gcagaatcgg gtgatctttt
     6121 agctgtttat tccacgggag cttatggata ctcgatgagc agcaactaca atcgagcgac
     6181 acgaccagca gttgtttttg tcaataatgg ccaatcaaga ctgattgttc gcagacaagc
     6241 attttctgat ctactaaggg gggaagtttc ctatgatcct tcataaatat aatggctgcg
     6301 gaaatgattt tatcttatta gattacgcag aagacacaga ttatagtcaa ttagccgctt
     6361 ctttatgcac aaaagaaaaa tatgatatag acggattgat cgccgtaaaa atcgatccgt
     6421 tggaaatgat ctattacaac aaagatggca gccgcgcgcc gatgtgcgga aatggcattc
     6481 gctgttttgc tcgatacgta aatgatcaga acatgatgaa tgaacaggaa ttcaacgtag
     6541 agacattagc aggcacaaga aaaattacgg tgttggatcc ctcacctttt tattgcagcg
     6601 tagatatggg agtgccagat gattctccgg aaaaaatcaa agctaatcaa acttatccaa
     6661 taaaaaacca ggaaatagag atcaatggtg aaaaagtaac gatcactagt ttatttttag
     6721 gaacgattca taccgttgtt tttgttgaaa atgcgcgtga ggaagtctgg agaaaaagag
     6781 gtgaactgat ctgtcatcat cctttgttca aagaaaaaac caatgtcaac tttgtagaag
     6841 tagtcaatga acaagaattg atcgtccgta cctatgaaag aggagtaggt tggacacttg
     6901 cttgcggtac aggttgctgt gcctcttatg tggttgctaa ggaaactggg aaaatttcag
     6961 cagatcaggt agttgttcac ttggaacaag gagacttgat gatctctggt gaggatgcga
     7021 tacaaatggc tggcccagca gttcatgaat ggacaagaat attggaggaa tgaagatgat
     7081 aaaaggttcg atcgtggcgc tgatcacgcc gatgaatgaa gagggatcag tagattatgc
     7141 tggtttggaa aaattgatcc aattccattt agatgaacaa acagatggat tattagtttt
     7201 aggtacaaca ggagaatctt ctacgctcac acaatctgag gaggagcaga tccttcaact
     7261 gacagtaaag aaagtggctg gccgtgtgcc ggtgattgca ggagctggaa cgaataatac
     7321 gaaagaaacg attgaaaaag cgaagcattt tgcttctttg ggggcagacg cacttttggt
     7381 catcacccct tactacaaca aaacaagtga tgcaggacta gctgctcatt ttacagcaat
     7441 tgcagaagcc tcaccgattc cgcttatttt gtataatgtt ccttctagaa caggcatgtc
     7501 gattccaatc catgtattag taaatttagc agaacatcct aatatcattg gtttgaaaga
     7561 agcctcagga gatatggctt atgtgatgga tgccgctcgg ttgattggag aagaattctt
     7621 cctttacagt ggaaatgatg atttgatcct accagtaatg agtgtaggag gaagcggtgt
     7681 aataagtgta tgggcgaata tccaacctaa aatagtccat gaattagtaa aagatacgca
     7741 ggacggaaga tggcagcaag caaaagaaaa gcaattaaat gcacttgaac tgatccatgc
     7801 cttgttcagt gagaccaatc ctattcctgt caaagcagcc atgtcattat tagacttacc
     7861 ttccggacct ctacgcctgc ctttagtttc tctttcaaaa gagaaaaaga aacaattagc
     7921 tcagcttttg ttaaaagaaa ggacggttga aaaatgaaaa tcggactgat tggcagtgga
     7981 cagatgggaa atagagtcga agaagttgca caagaaagag gagatacggt ccttctttta
     8041 cggacggcac ctaaagaagc aactacgctt gcttttacgg aactgccaga actgcttatt
     8101 gatttttctc atccagataa tttagagaaa atcctttcgt atagcttatc atatcaactt
     8161 ccgttagtca ttggcacgac aggttataca caatcacagt tccaagaaat aaaagaacat
     8221 gccaaacatg tacctgtgat gtatagtgct aatttttcgt tcggcatcat ggtgatgaat
     8281 caactaatca agcaagcagc tgcaatgttg caaggctggc agatcgaact gattgaaaaa
     8341 catcatagtc gtaaaaaaga tgcaccatct ggtactgcaa atatgctgct tcaaacaatc
     8401 caagaagtgc aaaagctgca gcccgtatac aactggcaag ggaaaaaaag agaagaaaac
     8461 caaattggtg tacacagtat tcgtgcaggt tctttacctg gtgaacatga tgtattgttt
     8521 gctgctactg atgaaatatt tacgatcaaa catgaatctt tttctaatcg aatctttgct
     8581 gcaggcgcag tagaagcagc ggactggttg aaagatcagt caccaggtta ttacaaatta
     8641 gaagatttat taatggacaa aggggtgtaa aaaacgtgga agctcaagaa atcatccgct
     8701 acattcaaac ggcatctaaa aagacgcctg tgaaagtcta tctgaatgta accgagccaa
     8761 tcgaatttaa agaaagtaaa gtttttggtg aaggaagcag cttcgttgtt tttggtgact
     8821 atgagacgat tgctccggtt ttagaagctg aatcagaaaa aatcattgaa atcgaaatcg
     8881 aaactgctgc aagatacagc gcagttcctt tgctagatat taaaaaaatt aatgctcgta
     8941 tcgaaccagg tgctattatc agagatcaag tgtcaatcgg caacaatgcc gtgatcatga
     9001 tgggagcgat tatcaatatt ggtgcagtaa tcggtgaaaa cacgatgatt gatatgggtg
     9061 ctgtcttagg tggacgagcg acagtgggca aaaactgcca tattggtgca ggagctgtct
     9121 tagcaggtgt gatcgaacca gcatcggcca aaccggttat cgtagaagac ggcgtactgg
     9181 taggtgcgaa tgcagtgatt gttgaaggtg tccatatcgg aaaagatgca gtcgtggcag
     9241 caggagcagt ggttttagaa gatgtggcag cagaaactgt tgtcggtgga atacctgcac
     9301 gtgtattaaa aataagtgat gatcagacaa aagaaaatac agcattgatt gctgcgttac
     9361 gcgaattata gaggagatgg agaaaaatgc gcgaaataga tacctgtatt gtgggggcaa
     9421 ccggattagt cggccaaacg atgctcaaag tgttagaaga atatgatttt ccagtaggac
     9481 gattgaaatt attagcttca aaacgttcag ccggtaaagt ttgtgtattc aagaaaaaga
     9541 aacacactgt acaggaattg acagaaactt catttgaagg atatgattta gcgctatttt
     9601 ctgcaggtgc ttctgtatcc aaagagtttg cgccaatcgc acgaagtcag ggactatttg
     9661 tcatagataa ttcctcagca tggcgggaag attcggatat tccattaatc gttccagagg
     9721 tcaatctgga agactataca ttgaatcggc tgattgcaaa tccaaattgt tcaaccattc
     9781 aagcggtact tccgcttaaa gctttacaag aagcctttgg tatccagcga gtcaattatt
     9841 cgacctatca agcagtttct ggttccgggc aaaaaggcat tgaagatctt catcgtacgc
     9901 aaaatgacga ggaaccagtt ttgtatcctt ataatattag ccaaacggtg attccggaaa
     9961 tcgatcagcc tttggaaaat gggtatacaa aagaagaaca gaaaatgata aatgagaccc
    10021 gtaagattct gcatcagcct gctttgccag tatcagcaac ctgcgtacgt gtgccaatcg
    10081 aaaatggaca tggagtctct gtggcagttc aactgcaaaa agagtttacg acggaagaaa
    10141 ttagagagtg tctcagccag tttccaggga ttcaattaga agatgatcta gcagcacata
    10201 aatatccgac gagcattctt gctagaggaa cagatatggt ttatgttggg aggatcagaa
    10261 aagacacttc tttagagaac ggattgttgt tctatacgac tgccgataac atacgcaaag
    10321 gagccgctgc gaatgccgta cagattgctg cagctttaat gcagaaaata gcggaggtgg
    10381 caagatgagt aatacgctga aagtagcgaa attcggcgga acatcgatgt ctcatgaaga
    10441 gcaattcaaa aaagtccgta caattgttct ttcagatccc aatcgccaag tgatcgttgt
    10501 ttctgcttta ggcaaacgta cgtcagatga tgacaaagta acagacttac tttatttgat
    10561 ttatgcttac cttcagcatc atgttgattg gacacccctt tggaaaagga tttgtgatcg
    10621 tttcattcaa gtaagagatg ttcttgccct gcagttacct attgaagatg aactagcacg
    10681 catacagaaa caactggaag acgaaaagat aactgaagat tatttagtaa gtagaggtga
    10741 atatctgact gctcaactga tggctgagta tcttggttac cagtttattg acgcaaaaga
    10801 cctgattttc tttgactatg atgggaaaat cgatcaggaa aaaacagcac aggaaatcac
    10861 aaaagcattt aaaagatatc cgaaaatggt tgttccaggg ttttacgggg cgaaccctgc
    10921 aggaaaagaa aaattattgg gccgtggggg aagcgacatt accggcgcga tactggcgaa
    10981 gatgttgcaa gcggaaagtt atgagaattg gacggatgtt tcaggaatca tgatggctga
    11041 tccgcgaatc atcgatcatc ctaaaatcat cgaggaaatc tcttttagag aactgagaga
    11101 gatggcttat atgggggcta acgttcttca tgaagcagct gttttcccag ttcaagaggc
    11161 tgatatcccc atccaaataa aaaataccaa tgatcctttc gctcaaggga caaaaatatc
    11221 gaatcacgaa atagaaaagg aaaatggact gacaggaata gctggacgca aggattttct
    11281 ttccatcact ttattcaaac gtcatatgtc cgatgaaatc gggtttatct ggaaagcaat
    11341 gagcattttt gctaaacatg agatatcaat cgaacatatt ccttcaggga tcgacaatat
    11401 cggagtgatc gtctcagcag aagcgattgc cgataagtta tttctcatca cgaaagaatt
    11461 aaaagaaaca cttggcgtgg aagaaatcgt cgtgatcgaa gacttagctt tgatctctgt
    11521 cgttgggggt ccgcataaag aattgattgg attatctggg aaagtgttat cgatattgaa
    11581 caaattagaa attcgcacat cgatcttatc acaaggagca caggagttga atctgatcat
    11641 cggtgtaccg aataatcaat atgaaacagt agtgaagggt atctatgaag ggatggtgaa
    11701 tacggatgct gaaagaatat cgaatggcac tccatcaaat tcctgaaatc gggtttcatg
    11761 aattcaagac aaaaaaatat ttatatgaac aagtaaaaaa cagcgaggcc gttatccatg
    11821 aaatcggcga aacaggacta ctcctttatt ttgataatca gcaagaagaa acgattgctt
    11881 ttcgaacaga tatcgatgca ctgccagtca aagaagaaac gaatctctct tttgcttcta
    11941 agcatgaagg ttatatgcat gcatgtggtc atgacggaca tatggcgatg cttttagggt
    12001 tgactgactt tataactaaa cacattgagg atcttattta taatgtagta ctgatctatc
    12061 agccatcaga agaaatttcc ggtggcgcac aaagcgttat tcagtcagga ttgttggata
    12121 aatatgaagt acaagcaata tttggctttc atctatggcc tggactagct aagggagaag
    12181 ttttctctcg accaggacct ttgatggcac aaagcagtga aacagacatt atcattaaag
    12241 gccagtctgc acatattgct tctagtgaaa aaggaatcga tagtctggag gcagctgtac
    12301 gatttttgaa gaatgtttat gattttgacc ggcaattacc ggcagagtgg aatcatctaa
    12361 tgaaatttgg ccaaatccaa ggtggaacga tccgaaatgt tttagctgga gaagttattg
    12421 tatccggaag tatccgttct tacagttcag atatgcaaaa ttatttgaag aggggattag
    12481 accatttagc agaacagttt cactctacag ctactatttc ttttcgctat aatgacggct
    12541 atccagctgt aatcaaccat agaggcttat atgcagcact gttagattca aacaaactac
    12601 atgaattaga tgctccagtt cttcaagccg aagattttgg catatatacg caacaatatc
    12661 catgtgtatt tttcttttta ggtgtcggtg atacccctgc tttacatgat ccgacgttcg
    12721 attttgatat ggatgtttta gaaaatggtg tagaatggta caaaacgatt ctttttacag
    12781 aaaatcttct tgtaaaaatc gatagcagtt caaaagagga gcgagtaaat aatgatgaat
    12841 ttatccaatc gatttagtcc taggctttct agaatagaag tatcaaaaat acgacaattc
    12901 gatcagcaaa tatcgtcgat accagatgtg atcaaactca ccctgggaga accggatttt
    12961 ccaactcctg aacatgtcaa gcaagcagga atagcagcga ttgaagaaga cttttctcac
    13021 tataccggaa tgagaggatt agaggaactg cgggaagcgg cttgtatatt tcagcaacag
    13081 cgttatggat taacttatga tccgcaaacg gaagttttga cgacagttgg tgcaacggaa
    13141 gcgattgcct ctgcgttgtt atctgttttg gaagaaggag acaaggttct tattccagcg
    13201 cctgcttatt caggatatca gccattagtg gaactagctg gtgctgaatt gatcccgata
    13261 gatacttctg acacagggtt tgtctgtcag ccggaacaat ttgaacgagc atttgaacaa
    13321 tatggatcag ctgtcaaagc agtcatttta aactatccta acaatcctac tgggacgaca
    13381 ttgtctgcaa aacaattgaa agcaatcgct gaggttttaa aaaaatatcc ggtatttgtt
    13441 ataagtgatg aagtatatgc tgaattgact tatagtggaa cgcatatgtc catagctact
    13501 tatcttccag aacaaacaat cgtgataagc gggttatcca agtcacatgc gatgactggt
    13561 tggcgagtgg gctttatttt tgctcaaaaa gcccttattg acgaactaat taaagtccat
    13621 caatatctgg tgactgccgc tacaacgatg tcgcaaaaag ctgcggctga agcgctaata
    13681 aatggggtga aagatagcga gaatatgaaa gagcaatatc aaacacgaag agactatctg
    13741 gtccagcaat tggcgccttt aggatttgaa gtgacccagc caaacggtgc attttacttg
    13801 ttttgcaaac tcccagctgc cattcaaact gactcttggc agttttgtgt agaattagcg
    13861 gaacaggcaa aagttgcgtg tatcccagga attgcatttg gcccagaagg agaaggttat
    13921 atccggattt cttatgctag cagcatggaa aaattacatg aggcctgcaa acggatcaaa
    13981 gactttttaa cagaacagtg attcatagat tttatcaaaa aaacaatcgt taattttgcg
    14041 gtatattctg caaggagacg attgtttttt aaatttagtt caaatgaacg cgtttctttt
    14101 gattcataac taatgtaatg ttaagtttaa attgtttaga atgattttaa aagaatattc
    14161 aaggaggttt catcaatgga aaaaatcaaa gttgtcattg taggtgcatc tcatggaggg
    14221 catcaatcga tcttggaact attgacacga tacggtgaaa atgtagatat cacgctattt
    14281 gaagcaggag actatatttc cttcatgtca tgtggtatgg agctgtattt agaagacaag
    14341 gtaacagatg taaatgatgt acgtaatttc agaccagaaa actttccgca atccaatgtt
    14401 catattttaa ataatcacga agtaaaaacg atcgatgccg ataaaaaaac agtaacggtt
    14461 actagcgcat cagataacga aacaaaagaa tatccttatg acaaattgat tttgagttct
    14521 ggtgtcaaac caaacaatct gccagtacca ggagcagatc tagaaaatgt ctacttgatg
    14581 cgtggataca attgggcaac caaaatcaaa gaaaaattaa atgatccggc tattaaaaaa
    14641 atcgctgtcg taggtgcggg ttacattggg atcgaagcag cagaagcaag ccgaaaagct
    14701 gggaaagaag tcgtattgct tgatgtgatc gatagacctt taggcactta tttagatgct
    14761 gagatgacag atattttaga acaacaccta aatgaaaacg gtattgaagt tttgacaaat
    14821 gcaaaaatcg aagcttttac tggtaacgga aaagttgagg caatcaaaac aagtgaaaaa
    14881 gaaatcccag cagatctagt cattcaagct gccggtgtga aggcaaatac agaatggtta
    14941 aaagggatcg tcgacttaga tgaacgtggc tggatccaaa caaatgaata cttgcaaacg
    15001 aatcttccag atgtgtatgc agtaggagat gctacacttg cttattctat cccagcacgc
    15061 aaaaaaatgc cgatcgcttt agcgactgtt gcacgtagag aagcacgtta tgtagtaaaa
    15121 catctttttg aagaagtacc aaacaaaccg ttcggcggag tcgtaggttc ctctgcatta
    15181 agtgtctttg actatcattt tgcagcaagc ggattgaata gctttacagc agcaaaagca
    15241 ggagtagatg tacgagtgtc ttattatgaa gatacgttac gaccaaaata tgtaccagaa
    15301 gaacaaggaa atccaaaagt gtccatccaa ttattctcgg atccaatgac ccatcaattg
    15361 ctaggaggag cagtattatc tacctatgat gttacaggtc aaggaaatgt attggcacta
    15421 gcgatccaaa acaaactgac tttagaagaa ctagcagaag ctgacttctt cttccagcca
    15481 ggctttgacc gacaatggag catgttgaat ctagccgctc aacaagcgtt aggagaagaa
    15541 ccatttgtag aataagaaaa cgaaatattt gaaaagaggt tgtgaaaaag ctgccttgca
    15601 tcaagtaata agaacagcca agtaaaaaca gcttcttatg tttttaactt ggctggactt
    15661 attaccgcag atgcaagctt ttgaacaccg tttattttca aaaaagggac tgtgacacga
    15721 tttgtgtacc gacccccaaa agttagacca aaaaatctaa cttttggagg tcggtatttt
    15781 ttatggttaa atatactttt gaacttaaat taaagatcgt tcatgattat ttggatggca
    15841 aaggcgattg gaccgtaaaa atccagatca agagattgaa gcggaaatgc ttaaaattcg
    15901 ggagaagcac aaggattatg gctgtttacg gatgaccaat gaactaagaa accgcggttt
    15961 ctctatcaat aaaaagaaag ttcagcgctt gatcaagaag ctaggaataa aagtaacggc
    16021 atacacgcgt aaatcacgtc gctacaattc ttatcgagga aaagt
//
LOCUS       DADGKS010000060        15632 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.060, whole genome shotgun sequence.
ACCESSION   DADGKS010000060 DADGKS010000000
VERSION     DADGKS010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15632
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.060"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..281)
                     /locus_tag="JXV47_002121"
     CDS             complement(<1..281)
                     /locus_tag="JXV47_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar nucleotide-binding protein"
                     /protein_id="HAX1488142.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNA"
     gene            complement(379..1407)
                     /gene="rfbB"
                     /locus_tag="JXV47_002122"
     CDS             complement(379..1407)
                     /gene="rfbB"
                     /locus_tag="JXV47_002122"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HAX1488143.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            complement(1429..2001)
                     /gene="rfbC"
                     /locus_tag="JXV47_002123"
     CDS             complement(1429..2001)
                     /gene="rfbC"
                     /locus_tag="JXV47_002123"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HAX1488144.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            complement(2015..2881)
                     /gene="rfbA"
                     /locus_tag="JXV47_002124"
     CDS             complement(2015..2881)
                     /gene="rfbA"
                     /locus_tag="JXV47_002124"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HAX1488145.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            complement(2981..3715)
                     /locus_tag="JXV47_002125"
     CDS             complement(2981..3715)
                     /locus_tag="JXV47_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAX1488146.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            complement(3693..4520)
                     /locus_tag="JXV47_002126"
     CDS             complement(3693..4520)
                     /locus_tag="JXV47_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAX1488147.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            complement(4520..5320)
                     /locus_tag="JXV47_002127"
     CDS             complement(4520..5320)
                     /locus_tag="JXV47_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAX1488148.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            complement(5313..6452)
                     /locus_tag="JXV47_002128"
     CDS             complement(5313..6452)
                     /locus_tag="JXV47_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HAX1488149.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            6492..6650
                     /locus_tag="JXV47_002129"
                     /pseudo
     CDS             6492..6650
                     /locus_tag="JXV47_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008788611.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-binding domain-containing protein"
     gene            complement(6657..7850)
                     /locus_tag="JXV47_002130"
     CDS             complement(6657..7850)
                     /locus_tag="JXV47_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAX1488150.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            complement(7929..8135)
                     /locus_tag="JXV47_002131"
     CDS             complement(7929..8135)
                     /locus_tag="JXV47_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HAX1488151.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            complement(8128..9270)
                     /locus_tag="JXV47_002132"
     CDS             complement(8128..9270)
                     /locus_tag="JXV47_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAX1488152.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            9782..10417
                     /locus_tag="JXV47_002133"
     CDS             9782..10417
                     /locus_tag="JXV47_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1488153.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            10553..10645
                     /locus_tag="JXV47_002134"
                     /pseudo
     CDS             10553..10645
                     /locus_tag="JXV47_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323349.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            10759..11394
                     /locus_tag="JXV47_002135"
     CDS             10759..11394
                     /locus_tag="JXV47_002135"
                     /inference="COORDINATES: protein motif:HMM:NF012655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAX1488154.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            11501..12739
                     /locus_tag="JXV47_002136"
     CDS             11501..12739
                     /locus_tag="JXV47_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004081244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAX1488155.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            12966..13385
                     /locus_tag="JXV47_002137"
     CDS             12966..13385
                     /locus_tag="JXV47_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009269612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAX1488156.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            13390..13629
                     /locus_tag="JXV47_002138"
     CDS             13390..13629
                     /locus_tag="JXV47_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008788617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1488157.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(13854..14777)
                     /locus_tag="JXV47_002139"
     CDS             complement(13854..14777)
                     /locus_tag="JXV47_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HAX1488158.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(14809..15573)
                     /gene="map"
                     /locus_tag="JXV47_002140"
     CDS             complement(14809..15573)
                     /gene="map"
                     /locus_tag="JXV47_002140"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HAX1488159.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
BASE COUNT         4704 a         3077 c         2779 g         5072 t
ORIGIN      
        1 gcattcacag cttttgctgc aagtgctaca tttcttgtac catcaacatt gatcttctca
       61 tctaattctt ttgcttcttc ttctgcttta tctactgctg tgtaagctgc acaatggaaa
      121 ataacatcag gttttaattc tgtgatgtaa gccattgttt tctcggcatc tgtgatatcc
      181 aagtcttttg catctgttga aacatattgc agattttttt catctaataa atggcgcaat
      241 tctgtaccta gttgcccatt tcctccagtt aataaaaaca tatgattatc cgctccttga
      301 tttttatttt aaaaaagaga caggcgagcg cctgcctcac atgtgttttt ccattaatac
      361 agtgacattt tctctgtatt attgtccatt tttggcatat gctgcttcaa cggcctcttt
      421 ttcttttttc caccagtctt catgttcttc gtaccatttg atcgtgtcag ccaacccatc
      481 acggaagttc gtaaactcag gcttccatcc taactcttcc cgtaattttg tcgaatcgat
      541 tgcataacgc aagtcgtgtc ctgcacggtc gtttacatgg tcgtacgcat cttttggttg
      601 acccatcatt tctaagatca attccatcac ggtcttatta tcttcttcac cgtctgcacc
      661 gatcagatag gtttcgccaa ttctgccttt cgtcaaaatc agccacactg ctgaagaatg
      721 atcattcgta tggatccagt cacgaacatt ctttccttcg ccatataatt ttggacgaat
      781 accgcttaag atattcgtta cttggcgagg aataaatttt tcaatatgct gataaggacc
      841 atagttgttt gaacagtttg aaatggttgc acgtaagcca aaagaacgca cccatgcttt
      901 tactaacaga tctgaaccag cttttgtaga agaatatgga cttgaaggat tatatggtgt
      961 ttccgcagtg aatttttctc cttcgccttc cccatgtcct ggcaggtctt cacgtaatgg
     1021 aagatcgccg taaacctcgt cagtagatac gtgatgatag cgtacatcat acttgcggca
     1081 agcttctaaa agtgtatacg taccaatgat attcgtttgt acaaatggga aaggatcttt
     1141 taatgaatta tcgttatggg attctgccgc gtaatgaaca actgcgtccg cttcttttac
     1201 tagacggtcc actaattctg catctgcaac atctcctacg accaattcta cgcgatcgct
     1261 aggaagtcca gccaagttct ctttgtttcc tgcataagtc agtttatcca aaacagtgac
     1321 atgcacttct ggatgattgt ttaccacgta atgaacgaaa ttagagccga tgaatccggc
     1381 acctccggta acaatgatgt ttttcataag aaaatttctc cttaattctt agatttctcc
     1441 gtaaacaaat ggattttctg cttcaaattc ttttaatgtc ggatgacggt gatctttttc
     1501 cgacataatc gctcttgatg gatcaattgg ccaatcaatc gctaaatctg gatcatcaaa
     1561 tgcgatgccc ccatctgctt ctgcattata gtaattatca cacttataaa ggaagttcac
     1621 atttggtgtc aaagtaacga atccatgggc atatccttta ggtacaagca actgtcgatg
     1681 attatgttca gataagataa atccgtccca ttgaccataa gtcgggctac ctttgcggat
     1741 atccactact acatctaaaa ctgctccagt gactacccga atcaattttg tctgtgcagc
     1801 ttctcctttt tggaaatgaa gcccccgaag gacaccagct tcagctgata gtgaatggtt
     1861 gtcttgaaca aagtcatatt tcaatccatg ttctgcaaat tttgcttttg aataactttc
     1921 tgtgaagaaa ccgcgatgat cgccaaagac gtccatttct acgattttga catctgttaa
     1981 ttttgtatct gttactttca tctgtaagga ctccttattc agcggccaaa ttcaataaat
     2041 attgaccgta ttgatttttt ttcaatggct gtgcaagggc cagcaattgt tccttatcga
     2101 tgtagcccat acggtaagca atttcttcca aacaagccac ttttaagttc tgacgttttt
     2161 caattgtttc gataaaggta gatgcttcaa gcaatgattc atgtgttcct gtatcaagcc
     2221 aagcaaatcc gcgtcccata agttctacgg atagttttcc tttatccaaa tatgctttat
     2281 tgacatccgt aatctctagt tctccacgtt ctgaaggttt gataccttta gcgatagaaa
     2341 ttacctcatt gtcataaaaa taaaggccag ttacagcgta atttgatttt ggctgagcag
     2401 gcttttcttc aatcgacaaa gcttgcatat tctcatcaaa ttctactaca ccaaagcgtt
     2461 ctggatcatt gacatgatag ccaaatactg tcgcgcctgt atcttttgaa gctgctcgtt
     2521 gcaacatttt agacagaccg ccaccatagt aaatattgtc ccctaatacc aagcagacac
     2581 tatcatctcc aataaattct tctccaatga taaacgcttg tgccaatcca tctggacttt
     2641 cttgtactgc atattcgatc tgcagtccta aatcatttcc gtttccaaat aattccttga
     2701 aacgtggtgt atcttgtggc gttgaaataa tcagaatttc tttgattccc gccaacatca
     2761 gagtagacat tggataataa atcattggtt tgtcataaat cggcatcaat tgtttcgatg
     2821 ttgcctttgt taaagggtac agacgtgttc cgctgccccc agcaagaatg attcccttca
     2881 tggatatctg ctctcctttt tgatttcaaa tttcactttg ttattatctc atcaattgtt
     2941 atatttgtca tggaaatatt aaggatttaa acatctttta tcaacgttta aaccattttc
     3001 gtttgatcaa cgccgtaatc agatgaacac gccaagaaat tttttgccgt aatttagaat
     3061 gtgtttcaat ctcactcgcg tttaaatcat gtcttcggta cagagttaac ggttctctta
     3121 ggaacccagt cttctttcct cccagcaaac caatccacat atcatgcatc ggcacttctg
     3181 acgggatcgg caaaatatcg ggttttaaag aagaccggaa agccatacca gcaccaatat
     3241 agtgacttct tatcacatta ttaagccatc cttctttgga atttcgaaac gaaaaatacg
     3301 aatcatggat ctcttgcagc tcgctgtcca caatgattaa atcagaaact actactagct
     3361 gatccggatt ctgctcaaaa tagtcagtga tctttttcac ttttgtctcc aaccaaacat
     3421 catcttggtc tgccaaaaag attagatctc ctttcgtctg ctggatcgca taaccaaaat
     3481 tagcgatcaa tccttgacga ggccccgaaa aaagctggat tcgcttatct ttttctgcgt
     3541 attcagttaa tatatcccat gtatcatcta ctgacccatc atcagaaatg actacttcat
     3601 cttctgctga aagctgagat aaaatactat ctaactgctc tcttaaatat ctgcctccat
     3661 taaaggtagc tatacaaacc gaacgcacga attcacacct tccaattctt aacatatgag
     3721 cgcaaagtca tccgccagat atgccggttt ttgacggtca agaactgttt agctgttctt
     3781 aacaataatt gtcgtcggtg actggataaa tgcctttgat catattcatg ataaaatcga
     3841 ttttctgctt gtaaaataga acggtatcga ttacttgaaa ctttttcata gtctaaaacc
     3901 gaaagatcat gttccattcg tacaggaagg atctccacag ttttttccaa ctgatccact
     3961 ttccaaaaca gccaatgatc caaaaaatct aaagaaaaag caggattaaa cccgccaatc
     4021 ttttttagaa atttgacaga ccaggcaaca cctgaattga ttgccatgat tcgttcagct
     4081 gttgggcctt caacttctac tgcttgagct gtacgattga tataacgatc tgaatatagg
     4141 ggagaaactt gtcggctccc agaaaaaatc atcggaactg cagcaacaca ttcatctgta
     4201 aaggttactt tacgcaatag ttcaaaataa tcgtcgacta gcctcgtatc ctgatccaga
     4261 gtgacgagac aacgtgttcc ttcatctgct tgagacaacg caaaattata agccaccgct
     4321 aaaccaggat tttgcggatc atgatgataa acgatatttt ctttttcaaa cagctcattt
     4381 tgctgccttt gaggactatt atcgtaaata ataagctgaa tttgcttttc gctaagtgct
     4441 ttgcttaatg gtccataagc tggagattga ctgaatagtt gctgataaag cacaacgact
     4501 actaatattt ctggtttcat cagaaaaaac gccaccccca cttattgaaa aatttcatca
     4561 tagaagtcaa aaacacgcga aacagttttg catttcgatg cgcacccttc ccgtaaaaat
     4621 ggataactgc ataaaagggt gtgtacaata acttgtaacc tgctttttca aaactcaaac
     4681 acaagtcgtt gtcttcaaag tacatgaaga aacgctcatc aaaccccttt atctctttaa
     4741 atttatcaat atcagctacc ataaaactac ctgagatcat ccgtacataa ctattagcat
     4801 cagtaggcaa tcctcggcat tcaaacacag ccagtcgttt gtcaaacttt tttttgaccc
     4861 atttgaaagg cacaaagcgc aaaacgtaat caaaaacagc cagctgctca cggatgaggt
     4921 gctgagttgt tccatcttca ttaagaatct taggtgctaa catcgcacat tccggatgtt
     4981 ctttcaataa caagaccaat gctgtaactg tctcttcatc cactaaaata tctgggttac
     5041 aaataatgcc atagcgagaa tcgctagcta tcagattgtg attatgtcca taaccaaatc
     5101 cggaattttc atcatgaaaa tagatatcga tgtagggata tttcctatac tctgttagtc
     5161 tttttttgta ctcgggaagt gaattgttgt caaaaattcg gatttttact gctgtttcat
     5221 cttttacagt tgaaataaaa ttatctagtg tccgaaaaat tttatcactg tttgccgtca
     5281 caatactaat aaggatcggc tggtttaatt tgttattcat ctatatgacg gttccatttc
     5341 ttcaaatatt tctgttttac ttgcgtacgg tactctttat tccctaaaaa tcgcaatgtt
     5401 tttaaaataa actgatgttt ctcattgatc agaccaatca attcaaataa taaaattgca
     5461 gcaaacaaca tggcaataat caatatgatc gttccgattc ttccagtata attcatgacc
     5521 atagctgtga aagaaaacat caaagccatc gcataaatcg tcaggacagc acctttatga
     5581 gtaaagccta aactgattag tcggtgatga agatgttttt tatctgctgt agaaaaagaa
     5641 acacggtttg cttttctcct aatgatagca aaaaacgtgt ctgttaccgg cactcccatg
     5701 acgatcagca aagaaatcga tgaaacaaaa gtcacgttct tcagcccttg tagtgaaagg
     5761 acggccatca taaaccctag gaatagagct cctgtatcgc ctaaataaat ctttgccgga
     5821 taaaaattgt aaggaaaaaa accgataata cttgctacaa gacagaaaat aacaactgga
     5881 atatacactg tagaagcatg gaggaaaaaa tatccaatga ttcctatcgt aattaaaccg
     5941 atcaatgaaa tccctgccgc cagcccatcc aaaccgtcaa tcagattgac cgcattcgtg
     6001 ataccgaaga tccaaaaaat cgttacggga aaactaagcc agcctagttg gatatatcca
     6061 ataaaaggaa gcgtgaagga atcaatacgt atatctgcta caaaataaat aataagagaa
     6121 gcaatcaaga tccctatact tttttgttta ggtgtcagct catatttatc atcgagcact
     6181 cctgtgacta tgattactaa agaagcaatc aagatcggta caatatacga ttgagggata
     6241 attttacgga ataagaataa agtcgatata acaaatgaaa taaagatagg cagtccgccc
     6301 gctgaaggca ttggaacttt atttattctt ctttcatttg gtttgtcgac catacctgtt
     6361 tgtactgaaa tgattttgaa tacaggtgtt aatatcagtg ataataaaat tgtcagaaaa
     6421 aatcttataa ccatactaaa agaaacaagc atatgggcac ctactttaat taagagtcat
     6481 aattattata aattatatat gtctttttga ctatcttttt atatcttctc aaatgtccgc
     6541 aaagccttat tttatcggct ctacgggcat tttgcttttg tggtaaacct cgcatatcta
     6601 ggtctatctt cttatatttt ccctgtcaat cgtggttaaa atcgtggtaa atacttctat
     6661 gcgattagac gctgaacctc tgattttgcg gtatctatgg acgcatgagc gtaccagttc
     6721 attgtgatac tgatgtttga atgccccatg atatactgta aatctttcgg gttcatgttc
     6781 ttgcttgcca gccttgtgca gaatgtatgg cgtagcgtat gcggtgtaat atgtggcaag
     6841 ggattgtcct tgtggtgctt gttgtatttc tttaccatac ggataaataa ggcgttataa
     6901 tcaatggcaa cttttggatt acctttcgga ttgataaaca caaaaccgct gtgtccgtct
     6961 acctctatcg actttatctt tggtcggctg ttgataaccc gttgaaatgc ctgtatcgtt
     7021 tctttgctta atggcacttg ccttatcccg cttttcgtct taggcgtttc aatataatag
     7081 ccctgttcct tactctttag taactggtgg tcgataatca caacttcatt cttgaaatca
     7141 atgtcggcta ctgtcagtcc gcacagttcc gagatacgaa gtcctgtctt taacagtatc
     7201 agcacatcat cataatgctt gtgatacacg ttgtccgtct taataaatga caataaggct
     7261 tgctcctgtt cctctgtcaa tgcgactttc tctttggtat cattttctat gacttcactt
     7321 agcttgaaat caaaagggtt tttcctcaca taatcatctt gtatggctat gtagaatgac
     7381 gcttttaacg agcgtttatg gttgttaatg gtattgtagg aaaagccttt gtctttcatg
     7441 cgtaacgccc attctttagc gtcagagggt tttatcgtat caatgctcct agcacctaac
     7501 ttgtcctctt ttaataaccg catgagttgt tcccgttgtt tctgtgtgct tttcttcaca
     7561 tttgtcctct gtgcgttctg tttggcatag agttggcaaa gcgtcatttt cttgcctgtg
     7621 ctgtcgatac cgtcctcaat atcccgtctt atctgctgtt ccagttctcg aagtgagggt
     7681 ttttcccgtt ttccctttgg tgtcgggtct gtgggtgtca atctccaagc atacacatat
     7741 tttgtgtttc ccaatgcgtc tacatattta tataagtatt ttccgtctgt tcgttggctc
     7801 tctccagtat gcaggatacg acctttgtta tcccgtcttt tttctttcat ggtgtctgct
     7861 cctttccttg ttggaaagag ccttgatatg acttgtgttc atcataacac atacaaggct
     7921 catttgcatt agattgcgtc caatttatca ataacctttt caaactgtcg gcgtttaatc
     7981 tgtatgcggt tgccattcat aatgagccag ccagcgtcct tgttttcctc tgccaatcgt
     8041 cttaacttgt tttctccaat gcggaaatac tttgacgctt cttcaatggt aagggtgtat
     8101 ttttcccata cgggaatatc ctgtgtatta ctcataaaac accccctcac tttcgattac
     8161 gtctgatatg tccgtacaca tctgttccac aagcatttcc tgtttttcag aaaggtgggt
     8221 acattcatca atcattttca tgtagtttga acctgtcagc ctgtcgattt cctctatcat
     8281 cacgattgac ggcatgacct gtctttccag ccattgcaga gtgcgttcca tattgacagg
     8341 tacagggttc atttcaaaag gtaaactgtc atgggaaatg aatatctccc acaatggata
     8401 gtcaggaaat tccacaaaat cggtaatgag ataaaacacc agcccatgag ggttatacgt
     8461 caataacagt tcttcaactg cctgtaccgc ctttttgtca cgcagacgaa tttcaaaacg
     8521 gttgataata tcggtatgtt tctttttcgt tgcctgttcc ttttgttttt catacaggca
     8581 gaaatatttt gtgcttgcct ttgagccgat ataaagggta cttgctaaat tacggttttt
     8641 tccgcttaat tttccacctt gtacattttc atagttttta cagcgacatt ccgcaccacc
     8701 atttctgtat ttttcagata gcacaggaat atccagcaga ccgcacatat cattgattgc
     8761 caagtcaaaa cgtcggataa caccgccaca gtcaagacag cggtttaaga atgaatacca
     8821 gtccctgttc tgtgcctgta agacatattc catgttgcgt gagcctgccc cttttaattc
     8881 taaaaatacg cccatgtgtt catcatcaga agccatgacc ttgatttccc cgtaagcata
     8941 atgctcctta tagccataat acccatagtc ataatggata aaataatctg ctttcatgcc
     9001 aagcaccttt cggataactt ccaatgcgtc agtcgttgga aaacggacag acagataatc
     9061 aacgagcaga taaaaaggct tatcgcagat atagtaattc agacaacgca ggataatgtt
     9121 ctgtgtttcc ttgctggcgt tagcttttcc gttctcaaag cggttgatac tatatcttga
     9181 tacatgggta agacttgcaa gttctccttg tgaaagaccg ctggcaagac gtttgttctt
     9241 catttcaagt gcaaattcta aattgttcat tgtattcctc caatcccaca atagccttga
     9301 aatacctgta aaccaccttt caaaaagtgt gatatgtact atcttcttaa aacctctcat
     9361 tactactcac aggtttgggg gtgtatggtt tttgacttgt cttttgtgaa atagtgcccc
     9421 cctgttagat aacgggggca cagacaaggc tcgcaggctc gccagccgac aaagcatttc
     9481 ttccccttga cacaaggtgt catggcggta agcctgagag gcttccgcca ccgtgtcaga
     9541 aatactttgt cagcaagttc tgttttgcct tttctaacaa gttccatttc aaccgatatt
     9601 catatctacg gatttaatca gataggtatt tctttttgaa tgtttttata tttcattcta
     9661 ttgtgcttat tcgattacaa gaacatagta attcttatat gcttatttgt caatatcttt
     9721 ttttgccttt acaaatcata ttaagcatga tagacttata atagcgaaga tataacgaga
     9781 tatggagggt tatgcaatga aaataagcca tttaggaaat aatatacaga ccataagaaa
     9841 atttagggga atgaaacaac aggaacttgc ggacaaaatc ggtatcaata tgcagagcct
     9901 ttccaagatt gaaagagggt tgaactatcc tgcctatgaa acgctggaaa agataatgga
     9961 agtgctggac gttacgccca atgaattgtt gtcgggagaa tggaagtatg tcaatcaatc
    10021 tgaaaaggaa gtctgtcagt ttttaagagc cgaagaacgt ctaaatgcag aactgaaaca
    10081 tggacactat gataacttct ttgacagcga ggaagaatgg ctggaatatg agttagaaaa
    10141 gttacgggaa tatattacag actatatcaa cgggaaaagc attgaagcgt ccgaccttta
    10201 cccaatcaaa gaatttatcc agcatttgaa gtttcaaaaa ttattagacc gctatgatga
    10261 tttatacagt atggatatgt ttggggaaag catagaggga cataagtata agacacctta
    10321 tcaagtcgtg aaaatgataa acccgaactc aaaagaagat atggaactgt tacgagaagt
    10381 attaaggaat aacaattttg atgatgagga cgagtaactt ttttcctctt gcgagaagat
    10441 acagcaaaca aaaagcccga tcaagagtgc aaagcaccac caatggtggc aaagctcttg
    10501 acagggcttt ttcttttctg ttgtgggcaa tcaagaggaa gaaagggata aaatctgatt
    10561 tgtggtaaat caggcaaagg caacgcaggt atcacagtat gaattgacac cgcataagga
    10621 aagcaactgg aagattgtag aataaatgaa aaaggcttgc attctgcatt tttataaaat
    10681 tgcaagtctt tatattgaca agcataaaat actaagatat actttaatca gaccaacggt
    10741 ttgtattgga ggtaagttat ggcacgaaat aaatatccag aagaaacagt aaaactcatt
    10801 ttagatgttt ctacaaaaat gttttgtgaa aaaggatatg ataacacatc attgcaagat
    10861 attatcaatg aaacaaaact ttctaaaggt gctatttatc atcatttcga ttcaaaggaa
    10921 gatattttaa aagcaatttt tcaaagaatt ggaaatgaaa atgcagtaat atttgctaaa
    10981 attagagata acgatagttt aaacggttta gaaaagttaa gagaaatatt taagacagcg
    11041 gtattcaatt ctaaccaaag cgttttattg acagtttctc ctcaactatt aaacaatcct
    11101 cgttttcttg ctatgcaaat agaacaaatg tatgaaattg tagtacctga atttgttgaa
    11161 cccgttttag aacaaggtat caaggataag tctttggaga ttgaaaattc acatgaaatt
    11221 gcagaagtta tcatggtatt aagtaatgta tggctcaacc cattagttga aatgacggat
    11281 aaagagggta tggaaaaacg ttgcaataca ttcaatgccc ttttaaatgg aataggcata
    11341 gacacattat tagacgaaga aacaatttct gcatttatac agttttgtaa ataactgtat
    11401 ttgttatccc tatacgatag actgctctat aaaagagcag tttatttaaa ccattatata
    11461 aaccgacggt ctgtttgatt aaataaaaag gagagatttt atgcaagcag aaaaaaaact
    11521 ttttaatcgt gattttatac ttgttgttat aggacagata atttctttat ttggaaacgc
    11581 tatcctacga tttgcattac cgtactattt gttaaaagaa actggttcat cagctttgtt
    11641 tggtattgct acagcctgct cttttttacc tatggttatt ttgtcgctgg taggtggtat
    11701 tattgctgac aggacaaata aaagaaacat tatggtcata ctagattttg taacagcaat
    11761 cataatttta gtattttatt tgtcattggg aaaaattcct atcatacctt tgtttattgt
    11821 tgctttgatg ttactttatg gtatttctgg tgcatatcaa ccagcggtac aagcaagtat
    11881 tcctctattg gtatcatcag ataaacttac cgtcggtaat gctataataa atcaagtaaa
    11941 tactttagca aactttatcg gaccagctat aagcggagta gtttttcaat tttatggtat
    12001 caatcccatt ttaattgtta gtattatatg ttttactttt tcagccatta tggaaatttt
    12061 tatccatatt ccacaccaaa aaagacctcg tgaagtaggt gtaattgcag ttgctaaaaa
    12121 cgatttaaaa gatagttata cctttttgaa aaaggagaaa cccattttta tatccgtaat
    12181 ctttttggtt tgcattttca atttggtttt aagtgctgtt ttaattgttg gtctgcctat
    12241 cttaatttct gaagttttaa aaatgccaga tacactatat ggtttttcac aatcagcatt
    12301 atcattaggt ggtttatgtg gtggtatttt aacagctctt gttgcttcaa agttaaaact
    12361 aaaaaacctt tataccttgt tacttatttg ttctgtttct gttttactta tgggaatttc
    12421 gctattttta gaattgcctg caatagtttc ctactgggta gttacagtga tgtgctttgt
    12481 ggctatgggt gtatctacta tgtttgttgt tcaaatttac actcttgttc agacacaaac
    12541 accaccgcaa ttagtaggaa agataatggc tacgctggta gcagttgcta tgtgcggtca
    12601 acctattgga caaatggttt acggtatttt attcgatgta tttatacaag aaacatgggt
    12661 tgttatgttt gtagcttcta ttgcttcaat catgatttca atatattcaa aaagaatttt
    12721 tcaaaagtta gagatataat acaaggggtt aaatagtatg ttaggctaaa aacaatatat
    12781 aaaagaaaat ttgaaatctg ctaaaaggat agtgttataa aagaaagagt aatattgcag
    12841 tatttaaggc tcgcacaaat atatgttttg tgtgggcttt tttcttacca tttttctgta
    12901 tttctaaagg gtataaacgg tattccgttt atatatttca gcattagcag aaagggggtg
    12961 agattatgag gacatcttct ttcgagcata tcgtcagatt acagttcaat tctttaatgc
    13021 tgattgtcat taagaacaaa gtgaaaagtc gaaacagaca gcttgcaaga cattctaaac
    13081 gtgaagtatt gttttgtgaa atagccgaaa cgaaacaagt tgaacgtgga acgattgata
    13141 cctgttttta tgattgtgta tcatttaaag tcttgcactt tacaatttat gtatctgatg
    13201 aaacacttgg tacagtttta catagactgt cagaaaaaca gcgtagtgcg attttattac
    13261 gttattttca aggaatgaac gacagagaaa tttcagaact gtaccatgta tcacgttctg
    13321 ctatttgcag tagaagaact agaggactaa ggaagttaaa aatgcttttg agcgaaagga
    13381 agtaaagaaa tgagtaaaga ttatggctat ccctcttttg aattgatttg caaagcgtca
    13441 agcggagatg aaatggcagt taaagagatt ttgaagtttt atgacggtta tatttctaaa
    13501 ttatgcttgc gtccttttta ccactctgaa agtggtaaaa tcattatgca ggttgatgaa
    13561 gaactaaaag gagaaattca tacagacatg atgaaagcaa tattgaaatt tgaaatcgga
    13621 gtgaagtaat caactgtata aaaaaatcgg gagatacaca gtttcgtgct atctccctta
    13681 gtagttttac ggtcatatca aggctcattc aatcgtggta aattcgtggt aagatgagtg
    13741 tttttctata cttcaaaatg cttgaatgta tagtgtttat gcggataatt gaaaattaga
    13801 tataaaattt caaataaatt actgatataa atttacaata agaactcttg tttctacttt
    13861 tttttatgag aaaatttagt tttcaattta ttgaaccatt ttcggcttgg atctcgacgt
    13921 tttttgattt gatgacccgt cacgtattct tgaacaactg cattgatgat tccgcccaaa
    13981 atgatgatcg tagcagcaaa attaagccaa agcatgagta caataaaact tcctatgatc
    14041 tgataaccgc tgatcctcgt tgcaaaatac ctagcataga tactaaacac ttgtgataac
    14101 agcatccagc cgacagtagc gaagatcgtg cccggaatga tcgtcttcaa cttcaactga
    14161 gcattaggga caattaaata aatcaagaac atgatgacaa ataaagctac caatgtgatt
    14221 ggccacttca aagtttggaa ctgatcgata aagttcacgg gtatttgtac gattggctga
    14281 atagcatcca aaatcagctg tcccaaccca agaacgatag ttaccccact aatagcaatc
    14341 atgaacaaga caatgacaat tagtgagaag aaacggacga tcaaaaaatt ttttctattt
    14401 tctacgccat acgctttatt catcgcaatt tgcaaagcat tgatactttg acttgcagac
    14461 cataaagccg ctaatgcaga aacggataac aagcctcctg aactttgtgt caaaaggtct
    14521 ttgattgcag gaccgataaa ctggtaaacg gtctcaggaa tcacttctcg taaataggtc
    14581 agtacagtct cttgatcgat gtggagaaac ggtaaaatat taccaaaagc aataatcaat
    14641 ggaaataaag acaagagtaa ataataagca acgacgacag aggtcgtact catttctgaa
    14701 tcagtgatgc gcttttgagt cgtctcaata aagcgcatca gattttcatt ttgttttatt
    14761 ttgttccaaa ctttcatgta cctctcccgt acctattgac tggatagatc aataagtgcc
    14821 ttcttctcct tgtgatgtca aaattcttgg accatcttta gtaatagcca atgtatgttc
    14881 atattggcaa gaaagtccgc cgtctcttgt atacgcagtc cagccgttag gatccatttt
    14941 cattttccaa gttccggtat taaccatagg ttcgatcgtg ataaccatgc cttctttcaa
    15001 ccgcaaccct tttccagctt ctccgtaatg aggaactgct ggttcttcat gaatcgtagg
    15061 accaacgcca tgaccaataa aatcacgaac gatcgctaga ttttcgcctt ctacataagt
    15121 ttggatagca tgaccgatgt caccaatccg attccctact tgtgcttgct caataccgat
    15181 gtacaaagct ttcttcgtta cttccatcaa tcggtcgatc tcaggtgtag attctccaac
    15241 tacataggcc caacaagaat cagaaatgcc gcctttcaaa tcgatacaca tatcgacttt
    15301 taccaaatca ccgtttttca aaggcttttt acgagggaat ccatgacaaa tttcatcatt
    15361 tatactgata caagtcgcat attcataccc ttcaaagcca atttgcgcag caattccgcc
    15421 atgactctcg atatagtttc tgacaaatac ctcaatatcc caacttgtga ttcctggttt
    15481 tataaaatca cgcagatttt tatgtacatc tgctaataaa gctccagatt ctgccatcat
    15541 ttcaatttca cgtgctgatt ttaaagtaat catattttcg tctccttttt acaaatccct
    15601 ctcattttaa catagcggca tacatttagc ca
//
LOCUS       DADGKS010000061        15470 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.061, whole genome shotgun sequence.
ACCESSION   DADGKS010000061 DADGKS010000000
VERSION     DADGKS010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15470
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.061"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            59..1681
                     /locus_tag="JXV47_002141"
     CDS             59..1681
                     /locus_tag="JXV47_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488160.1"
                     /translation="MNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAFHINR
                     ALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLYIVTL
                     ITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPLILLG
                     FIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIFLIIK
                     LIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDSELLS
                     FGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLNIIQA
                     PWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNMVKEM
                     NFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPNKDEI
                     TFTFKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTIRYSY
                     TFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
     gene            complement(1948..3117)
                     /locus_tag="JXV47_002142"
     CDS             complement(1948..3117)
                     /locus_tag="JXV47_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAX1488161.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            3321..4496
                     /gene="mltG"
                     /locus_tag="JXV47_002143"
     CDS             3321..4496
                     /gene="mltG"
                     /locus_tag="JXV47_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HAX1488162.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            4632..5111
                     /gene="greA"
                     /locus_tag="JXV47_002144"
     CDS             4632..5111
                     /gene="greA"
                     /locus_tag="JXV47_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HAX1488163.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            5280..6011
                     /locus_tag="JXV47_002145"
     CDS             5280..6011
                     /locus_tag="JXV47_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HAX1488164.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            6008..7075
                     /locus_tag="JXV47_002146"
     CDS             6008..7075
                     /locus_tag="JXV47_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAX1488165.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            7082..7714
                     /locus_tag="JXV47_002147"
     CDS             7082..7714
                     /locus_tag="JXV47_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1488166.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            7854..8519
                     /locus_tag="JXV47_002148"
     CDS             7854..8519
                     /locus_tag="JXV47_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HAX1488167.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            8547..8840
                     /locus_tag="JXV47_002149"
     CDS             8547..8840
                     /locus_tag="JXV47_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HAX1488168.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(8908..9855)
                     /locus_tag="JXV47_002150"
     CDS             complement(8908..9855)
                     /locus_tag="JXV47_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAX1488169.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(10033..10836)
                     /locus_tag="JXV47_002151"
     CDS             complement(10033..10836)
                     /locus_tag="JXV47_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HAX1488170.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            10982..11896
                     /locus_tag="JXV47_002152"
     CDS             10982..11896
                     /locus_tag="JXV47_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAX1488171.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            11944..12414
                     /locus_tag="JXV47_002153"
     CDS             11944..12414
                     /locus_tag="JXV47_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HAX1488172.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            12499..13107
                     /locus_tag="JXV47_002154"
     CDS             12499..13107
                     /locus_tag="JXV47_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HAX1488173.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            13241..13441
                     /locus_tag="JXV47_002155"
     CDS             13241..13441
                     /locus_tag="JXV47_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAX1488174.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            14195..15421
                     /locus_tag="JXV47_002156"
     CDS             14195..15421
                     /locus_tag="JXV47_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HAX1488175.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
BASE COUNT         5270 a         2323 c         3014 g         4863 t
ORIGIN      
        1 tagtgtttaa aaaaaataaa tgatactata tgtaatataa aaaaacatga ggtggtatat
       61 gaatttgaaa aaaatttttt ctgtaaaaat atttatagtt tatgcatttg ttagtttatt
      121 atatttattt ccagcattta aaaacatgga aatatttggc ttttatgata cggcatttca
      181 cattaatcgt gcgttaagtt tagaatctat ttttagctcc cctattaatt ttgaaacgtt
      241 tagatcatat ggcatgcaag taaataattt ttacccatgg ttaactctat atcctttatt
      301 tttattgatc aagtttacta atttagcaat aggctataac ctttttcttt atattgttac
      361 gctcattact ctatttatat gtcattatgt aatgtatgaa attaccaaaa aacatgttac
      421 tagctccttt ttcgctatta tatatacaac atcttctttt aggagtgtag aaatatttct
      481 tcgaggggca atgggggaat tactcgcaat gtcaatactt cctcttattt tactcgggtt
      541 tataaagctt tacgactcaa aaaaagaatc ttgggttatg ttggcgatta gcatgacttt
      601 attaatttac actcatgttc tttctgtagc tatgactatg gtaatgatta taattgcttt
      661 aattattcaa ttttatcgga aaaagaaaat agaaatcttc ttaattatta aattaataaa
      721 agctgctata gttactttac ttctttcact agcgtttata ggtcctatga ttgagcagac
      781 attgtatcaa gatctgaata gaccttatgt ggatatatta caaaaaagag caatttatct
      841 gggtaaagag tttttgattg gaagtataga ttcagaatta ctatcatttg gtattggctt
      901 aactttgctt atttgtttaa ttatactaac atttaacttt aaaaaattag gaatcttatc
      961 taaaatcact tatataatgg gtataatatc tattctactt tgtacaaaaa tatttccatg
     1021 gtttgcctta caaaatactc ctttaaatat tattcaagct ccttggcgtt ttatgatatt
     1081 ttcaacattg ttcatatctt tttcagtatc tctatttatt tctccacagt tggaaaaatt
     1141 ttcttataca aggagaagaa attttatact attattaata ttagctattt caattttaaa
     1201 ttattcatca gtagttaaca tggtgaaaga aatgaatttt caaggaactt attctaatga
     1261 acaaatggaa aataaacttg aagaatttga gaattttgat tatgtaccta taggctataa
     1321 aaaagatcaa ttgcttttga aaaaccatca agttacagaa gatggtcaag ttatttatag
     1381 tagcttttct ccaaataaag atgaaattac atttacgttt aaatcttcaa aaggcaaaac
     1441 aatagtttta cctgtattcc ggtataaagg attaacggtt actgttaatt caaaaaatgc
     1501 tacagtacta aaacaaggag gtccttttgt tacagtaaaa agtgaaagtg gaataaataa
     1561 agtaacaatc aggtattcat acacattttt ttctaaaatc tcattattta tttctataat
     1621 cacgctaatt gttcttcttt tttattgcat aaaattaaaa ataagaacaa gccatgaatg
     1681 atttgctagc acatatttta gcaatctaaa gatactattt tagatttaat aggccctttg
     1741 tcaaataatg ttggtaaaga gaaatcttag aataatttgg acagaacaga aagaagaaca
     1801 cctctttctg ttctgtttat ttggaattaa agtctgtagc aaaaattgat ttttagattt
     1861 gtcccacact ctttcctacg tttagtcgag tacttttttt aagcaaatgc tattcaaaga
     1921 agtagtattt gctatctttt catcatatca gctatttgcc aacttagtag ttccttccat
     1981 caggtcatag atttggtttc ttagatcagc agtaggcagt ttgatagttt tgtcagcttt
     2041 tatattgctt tccatgatga tagcatcctg tgaatctttg ctaaatatag cagatgtatc
     2101 aaaagagtcg atatttcctt gcgacaggat ataattatct ccgctatata ccccaccact
     2161 atatggatgt ccattcgcat tttcacgcca taatgagaag agtaagtctt tggaaactag
     2221 ttttccagat aaaacttgtg taaacagcgt atttaaatca tagacggaca tactgatatt
     2281 accagtccct aattcgttat ggatctctgt ttcagattct gtcagtggtt taaagtaatc
     2341 atcctcttta gacatttgat aggatagtgc atgattggat gaatttttga cttggtcata
     2401 aaattttgta tgctgtaatc ctaaaggttc gatgatatca tcggtcaata atttttcata
     2461 cggttgattt gttaatttga tcaaaattcc agtcaatatg gtaaagttca atgaatcata
     2521 atgagaggtc tgataatctg taaattttaa gtgctgaatc gcaaattgaa cgacttcttc
     2581 atcagtcatc ggtatggttg gagaagcagt tcggtgcaag cctgagcgca tatacagcaa
     2641 gtcacggata gtaatttgct ggctgccagc aatttgtgga tagaattgag ccagcttagt
     2701 atctaaagaa aggtgcccac gctcgacttg ttttaaaatc aaaagagtag tcaatgcttt
     2761 ttgaaccgaa ccaatctgat aataaagaga aggatcattt ggttgttgcg tgagtttatt
     2821 cgcatagcca tagccttttt ccatgatgat gcgattattt ttctttacgt aaattgagcc
     2881 aatataatca ttttttctta atagttgatc gattttttca acgagctgtt gttcattggt
     2941 agtcagtatc aacttttttt gagctgattg agcatgggca actatctgag agtgttcatt
     3001 attgtaaaat tgccatccaa gaatagttcc tgtagagaac gcactaaggc taaacaacac
     3061 gacaacgatc attaaaaatg aatattttct ttttttagca tgttttcctt ttttcataat
     3121 agtttattta gtctcctttc ttttttacag aaagaataaa gctaaaatag cttgtatctt
     3181 gataacattt attttaatct tatagtaatg gatttactac ttacattttt gatagaatat
     3241 ttaaataaaa tcattcacgc caattcaaat atcatgtata atgaataaag ttacgaactt
     3301 gatagtaagg aggagttgtt ttgtcaggaa acaaacaaca cccaagtaaa gataaaaaag
     3361 aagccagtaa ggcagctaca gcagatataa tcgacaagcg gagaaatctg cgtaaaaaag
     3421 aagataagat tgtgaggaag atcattttag tgattgctct tacattattg attattggcg
     3481 gatttcttgg atttaccgtg tatcgttatg tagatagcgg gttgaagcct ttagataaat
     3541 cagatgacca attagtccaa gtcgagatcc cgagtggctc ttctaacaag cagattggtg
     3601 agattttgga gaaggacaat attattaaaa gcgggattgt tttcaattat tatacaaaat
     3661 ttaaaaattt aactggcttt caagctggct attatcagtt agcgcctaat atgactcttg
     3721 acgagattgg caaacagttg caagaaggcg gtacttctga gccaacaaaa gttgcagatg
     3781 ggaaaattgc cattccagaa gggtacgata tcgatcagat tgctgaacgg gtagcgaagg
     3841 taactggtaa agacaagaaa gaatttttag atttagtgaa tgatgagact ttctttaacg
     3901 agttgcacca aaaattccca gaactgttgg aaagtgcatc taaagctgag aacacaaaat
     3961 accgtttgga aggttactta ttcccagcca catatgatta ttacacgagt acttcgctta
     4021 aggatctagt gattgaaatg gtgaacaaga cgaatacggt catgcaaaac tattattcag
     4081 ctatcaagca gaaaaatttg actgtacaag aagttttaac tctagcttct ctagttgaaa
     4141 aagaaggcgt aaaagaaaat gatcgtaaaa acattgcaca agtcttcttt aaccgaatca
     4201 aagcaaatat gccacttcag tcagatatct ctgttttata cgcattaggt gaacacaaag
     4261 aattagtgac gtatgaagat acagctgtag attcaccata taatttgtat accaataccg
     4321 gctatggacc tggacctttt gacaatccaa gcgaagaggc aatcaaggca gtattagaac
     4381 cagcagaaaa tgactattat tatttcgtag cagatacgag cactggaaat gtttatttcg
     4441 ctaaaactta tgaagaacat atggaattag tggaaaaata tgtaaataat tcttagaaaa
     4501 acaggctcta gacattgatc atttttagaa aaacatttac atttgaagaa aagcgtggta
     4561 atcttttttg gactatattc ctcaaaagat taccttttgc ggtattttat cgaaaaaagg
     4621 agacgttaca catggtagag aaagtttatc caatgactct agaaggtaaa gaaaaattag
     4681 aaaaagaatt agaagaacta aaaacagtca aacgcggaga aatcattgaa cgaatcaaaa
     4741 ttgcccgcgg tttcggagat ctttccgaaa actctgaata tgaatcagcg aaagatgaac
     4801 aagcatttgt tgaaggaaga atcacaacaa ttgaaaatat gattcgtttt gctcaaatca
     4861 tcgataacga cggtgtagat gcagatgagg tatcaattgg taaaacagtt acattcatcg
     4921 aactaccaga tggagaagaa gaagagtaca cgattgtcgg aagcgctgaa gcagatccgt
     4981 tttctggcaa aatttccaat gattctccta ttgcgcaagc attgattggc aaacgtaaaa
     5041 atgatgaagt aactattgct actccaggtg gcgatatgtt agttaaaatc gtcaaagtag
     5101 aacaagcgta gtctgactga aagatctaga gagttcatct tactgatgat acactctaga
     5161 tctttttctc tttgtgtatt ttagatttca acaaacgatc ttacatctaa agtcctatag
     5221 ccaacagtta aaaaaatagg tatgatgaaa tgagaatgtg tcaggaggga gaaagagcga
     5281 tgaatagttc ttggcgtttt tttgtggtag ttgaagcact actgctgtta tttgctgttt
     5341 ggcaaatcgt aaacaatact ggacttttgc ttttagtgat attcggtatt ttcaatatat
     5401 atctagctat gcgcaaacat cctcgtacta aatttcaaaa ttttcaattg atattaggaa
     5461 gtttggtcat tttttttagc ttagtcaaca gtcctgcttt atggatgatg gctgtatttg
     5521 ccgttttatt tattggtctg aaaggtgtag agatttcagg gatagattta accaaaaatg
     5581 ctttttggcg aaagaaacag atcatgatga tccaaacaga gcaattaaaa acacataata
     5641 atgagcggaa aagacagcaa ttattcggta accaacgtat tggaaacgac gtctatgaat
     5701 gggacgatat caacatcgcc gtcatttctg gtgatactat catagatttg ggcaatacgc
     5761 ttttgccaaa agatgataat attgtgattg taagaaaagg gataggcaga acacggatct
     5821 tagtaccttt gggcgtagcc atccgattag agcatgcgac attagtagga aatgtcttgt
     5881 ttgaagaaga gcaattttct ttgaaaaatg aacaaatcaa aatctacagc agtgattatg
     5941 atgaaaaccc tcgtagattg aagattatta ctaatacctt gattggagat gtcgaggtga
     6001 tacgaatatg atgggaaaaa tatccagagc gatgctagct gtttattcgg ggattgcggc
     6061 tttccttatt attctatttt cacttttcac ttatttttat gccagcaatc aaagtcattg
     6121 gtggggagaa ttactgcgtg cacgtttatt atatgttccg cttatcttcc atttgttagc
     6181 catttcctta ggtgtaggat taattgtctt tctattatta tcacttattc aaaagacaaa
     6241 atacgggaaa atcgaagaaa agctgcgtgc actttcttct ggcaattatg aatccaaatt
     6301 gttgcttctt ccgatcccaa gtgcatcgga cgatttatac atcaaagata ttgataagga
     6361 aatcactaag ataaaagaaa aaatgattga agtatctagt gaattacaaa ttgtaacgag
     6421 ccgtccccaa tatgtagatg gacaaaccaa agaagaaatt ttagaattag aaagacatcg
     6481 attagcccgt gagctgcatg attcagtttc gcaacaattg tttgcagcaa tgatgatgat
     6541 gtcggcattg acggagcaag cagaaaaaag cgagacacca gaaatgtttc gcaagcagtt
     6601 gaaaatggta gcagagatca tcaacgcttc ccagtctgag atgcgtgcgc tgcttcttca
     6661 tctacgtcca gtcaatttag aagagaaaag tttaaagcaa ggtatcgagc agttattgaa
     6721 ggaattgcaa aataaaatcc agatttcgct gaaatgggat gtagaagatg taaaactatc
     6781 tagttccatt gaggatcact tgttccgaat cgttcaagaa ttgttatcaa atacattaag
     6841 acatgctaaa gccaatgaat tagaggtata tttgcacaaa atagacaata atcttttgtt
     6901 acgtattatt gacgacggaa cagggtttaa tatgaatgaa acgaaaacgg gaagttatgg
     6961 attgaacaat atcaaagaac gagtagctgg tattggtgga acagtaaaaa tcattagttt
     7021 taaaggtcaa ggtacaagtg tagaaatcaa ggtccctttg atgaaggagg catagataag
     7081 gatgataaaa gttttattag tagatgacca tgaaatggtg cgcttaggcg tctcttttta
     7141 tttatctatt caagaagaca ttgaagtaat tggagaagct gaaaatggac gacaaggcta
     7201 tgagaaggcg atgacacttc gaccggacgt cattttaatg gacttagtca tggaagaaat
     7261 ggatggtatc gaatcaacaa aagcaatctt aaaagattgg ccagaagcta aaatcattat
     7321 cgtaaccagt tttattgatg acgaaaaagt ttatcctgcc attgaagcag gtgcagcagg
     7381 gtatttgttg aagacctcta ccgcacatga aattgctgat gctataaggg caacgcaacg
     7441 tggcgagcga gtattagaac cagaagtgac aacaaaaatg atggaaaaaa tgagtcggcg
     7501 aaatgagcct gtattacatg aagaactaac gaatcgggaa aatgaaattt taatgctgat
     7561 ttctgaagga aaaagtaatc aggaaatagc ggacgaattg tttattacac tgaaaacagt
     7621 aaaaacacat gtttccaata tattggctaa gctagaagtg gaagaccgta cacaagccgc
     7681 tatctatgca ttcaaacatg gtttggtgaa ataaaaacga tgataaagag gataatcaaa
     7741 agctgagaaa ataactatta tttttcttgg cttttttaca ataatgatgc ttgcttttgt
     7801 ttttgtaaag gctttgttat actgagaaaa gaagatacta aaggaggaaa acggtgaaac
     7861 aaaattttgc aattgtaggt cttggacgat ttggcggaag tatctgccga acactgatcg
     7921 aagctggtca agaagtactg gctattgata gtaatgaaga tcgggtcaat gaatatatga
     7981 atatagccac tcatgctgtt gtggcaaatg cacaggatga aatgacactt cgatcattag
     8041 gcataagaaa tttcgatcat gtaattgtcg ctattggaga agatattcaa gccagtatct
     8101 tagttactct gatggtaaag gaaatgggcg taccaaatat tttagcaaaa gcccaaaatg
     8161 agtatcatgc cagagtactt gaaaagatcg gagctgatcg cgtcgtccat cccgagcgag
     8221 acatgggaat aaggattgcg cataatttag tgtcaaagaa tattttagat tacctagagt
     8281 tgtcagataa atattcttta gcagaaatcc gagtctccaa tcctaaattt ttcaacaaaa
     8341 cattagctga attaaatttc aggcaacgtt ttgacttaac agtagtcgcc atacgaagag
     8401 tagatcaaac ggttatcgct tctcctgcag cagatgaata tgttcgtgaa aatgataatc
     8461 tactggttat tggagagaca ggcgatgtgg atattctaga cgataagatg aatcaataga
     8521 aagaaaagag aaagtaggtt gttgggatga aattaacggt aacgccaaaa gcacaaaagt
     8581 ggtttgactc agaaattgat ctgccagaaa cttacggaat acgttttttt ggaaaagtct
     8641 acggcaaaac agaggttcat gatggttttt cgattggaat gtcagttgaa cagccagaac
     8701 atcctgtaaa gaaagtggaa attgatggga cacttttttt tatcgaggaa gcagatgaat
     8761 ggttctttaa aggatatgat ttacttgttg attatgatcc caacctggag gagccaacct
     8821 atcactttaa aaaacaataa aaaaagagag ggtgacacaa tttttgtcac cttctctttt
     8881 ttcttttgaa aatattgttt tcagctatta atatcctgca gacaatttta cttgattggt
     8941 ttgaagctca tgggtggcaa agtagctttt cagattggtt aaaaaaatag ccattaattt
     9001 cttttgaaaa tcaggtgtca aacctgcaat gtgggaagta atcagtacat tgtccatttt
     9061 ccaaagagga tgatcttgtg gaagaggctc ttcctcaaaa acgtctaatg ctgcaaagga
     9121 aagttgctgg ttatttaaag cctgcaccag atcttgtgtc ttaacagaag caccacggcc
     9181 aacattgatg aatacagatt ttggatcaaa gtgttcaaac atatgctgat caaagagccc
     9241 agttgtttcc tccgttagag gtaagatatt gactacgaaa tctacttcag gaagaacttc
     9301 ctttagttga tttaaagaaa aagtcttttc cattccttct gctggatgac cggatgtatt
     9361 gattccatag cagttcatgt ctaatgcttt gcattttttt gcaatcattt ttccaatatg
     9421 gccagttcca atgattagta tttttttccc ttggatagat tggtaatgga ccgatgaacc
     9481 taaccatttc atgtcactct gtgccttttg tgcttgaaaa agaccacgag aatacccaag
     9541 gatgattcct aagacatgct ccgtaatcga ttcactgtgg atgccactac catttgaaag
     9601 taaaatatgt ttctttgaaa aagtctcaag gggtagctga tcaacaccag ctgagataga
     9661 ttggacccat ttcaaggtag aagaggctaa tagtttttct tggtagtctg agttccagcc
     9721 caaactgatc tctacatttt gtagatcctc tggttgtaat tctgttttaa agatataacc
     9781 aggcgctata gtatggattt cttcgataaa ttcatcacga aatggacgat ctgcataaat
     9841 gattctttct gacatagtta atttcccgcc tttctttact ctaagtgtag cgcatacaag
     9901 aagaactttg aagcgccttg cttgtttttt gagaaagaaa tatttttcaa ataaaaaagg
     9961 ggctgtgaca aaaaaatgtc acaacctcta aaagggtcta ttgaagtaga aataacgagt
    10021 tgtctttatt tcttaattga tcgatatttt tgcccatcct ttgacagctt gagcaaaaat
    10081 aaagattcct gcaaaagcaa tgaaggcgct agtgtcaaaa gaaggaagaa agaccatcaa
    10141 gattgttgca attatagtag gcaatgaaat tgaatagatc aatgttttta aacaatcaag
    10201 aaaagtagct tttgttagtc gaaagcgtgc atagagaaaa gcagcaatgt tggtaaatag
    10261 caaagtgatc agcagattca gaaaactagg ataaatagaa aatataaatg tcaggacttt
    10321 tatccaaagt ggtatagatg cttcacttaa aaaagaacgg agctgcttac ctgttaagtt
    10381 ttttaaagat tcattggtgt agggaagttc taattggtta ttgttcaaca aagcagaagt
    10441 cgtgcctgta ttaggaagag ctatgataag tttgtttttt aacatcccga cactaacaaa
    10501 attccccatc aaatcagtag agatgtcctg ttctgttcgt tttccctctg gatcaaatgt
    10561 gaagataatg gagtttgttt ggtaaatgaa tccttctttt tcttcggttt gaagctgccc
    10621 gttttggatt gtaaaatcag gaatgcgagt agcaatcttt tgcccatcca attgaatgtt
    10681 gtttaagact tgaaaaactt gaaaagagat tggcaaagcc ataattatac tcaaaactaa
    10741 aagatagaca atggctttcc aaaatgggac atttctcgcc tcctttaggt ctttgaatcg
    10801 tataaaggaa ctgataatta attgttttgt tgtcataagt actcctcatc tagtagtgtc
    10861 atcacttgca attctagcga agtatcaagt gaaatacaag tgctttaagg aaacagctga
    10921 atgattggtg aaatatcaaa aaaatgttat tcttgtctaa agactatcca atataaataa
    10981 aatggaggaa ggaatagtgc ctacacagcc acagagatca tcaaaaaaac tatttggagt
    11041 agtggttttg aatgcggtga tcactttatc agaatttatt ggagggatta tgtcagggag
    11101 tttgtctctt gtttcagatg ctttccataa ccttagtgat acattggcaa ttattttttc
    11161 ttacggggca caaaaaatgg cccgaaaaga agcaaataaa aaacgtacgt atggctacca
    11221 gcgtttagaa atattgagtg ctttcatcaa ctcattcata ttgatcatat tatccttgtt
    11281 tttaaccgtt gaagcattca agcggttcac ttcaccagaa aagataaata gtcatttgat
    11341 gctaacagta gcagttattg gattgctcgc gaatttgttc tcagtattat tattacgaca
    11401 agaagcagat gaaagtttga atataaaatc tagttatttg catttgttaa gtgatacact
    11461 gtcttcggta agtgtgatta tcggagcaat tttgatccgt tttttcgata tctactggat
    11521 cgatccagtt attacactga tcatttcgat atatatattg atagaagcga taatggtgat
    11581 caaaaaagct gccgctattt tgatacaaag tgcacctgct atcgactatg aaaaaatgga
    11641 acaagaaatt gaagcaatcg atggggtaaa ggatgttcat catgtccata tttggcagta
    11701 tagcgaaaag ataattattt tcgacggaca tattgatttt gaagatcagc tactaagcga
    11761 gattgaaaag atatatcctc gtataatttc tttattaaaa ttaaaatatg gtattacaca
    11821 tgtgacgatc caagcagaga caaaggcaaa ggatcaaaaa aaattaattt ttttaaataa
    11881 agatgaaagt tattgaaata tagagtatga taaataagaa tttttaataa ggtaggttgg
    11941 ctcatgaagc agtatcgaca gttaaaagga tatttagaag caaaaggata ttgggagata
    12001 ctagtctatc tcttttttgg tggtttggct acgattgtaa attttgttag ttttgctctc
    12061 gcacgccaat attttgattt aagtatggcc ttatccaatt ctatttcgtg gttttgttct
    12121 gtattgtttg cttttgtaac gaacaaactt tgggtattcc attcaaaatc accgaatttt
    12181 acacatgcac ttattgaatg cggtaagttc ttcttctacc gtatcctttc ttacggattg
    12241 gacatggggg caatggtatt gttgatcaat gttatgaaca gcaatgagta tgtggcgaaa
    12301 atcatcactc aaattattgt tatccttgcg aactatattt tcagcaagtt gtttattttt
    12361 aaagaaactg aggtttttga agaagaagta ggtcaaagtg aaaaagacga ctaggcataa
    12421 caattgaaga atttccttct ctttgttact ctttgtaatg tagacattat taagaaaaca
    12481 ttgaggagga atttttttat gacttacaca ttaccagatc taccttatgc atatgacgca
    12541 ttggaacctt atattgacga agaaacgatg catctgcatc atgataagca tcacaatact
    12601 tatgtgacga atttaaattc agcaattgag aaatacccag aattaggcga aaaaacaata
    12661 gaagaattat tatctgatat ggacgctatt ccaacagata tcaagacagc tgtacgtaac
    12721 aatggtggcg gacatgctaa ccattcattt ttctgggaaa tcatggcacc aaatgctggt
    12781 ggcgaaccta caggagaaat aaaagaagcg attaatgaag cttttggtga tttttcttct
    12841 tttaaagaag aattcaaaaa agcagccgct ggacgatttg gttctggatg ggcttggctt
    12901 gtaatggaaa atggaaaatt agctattacc tctactgcaa atcaagattc tccattgatg
    12961 gaaggaaaga caccaattct aggtttggac gtttgggaac atgcttatta tttgaaatat
    13021 aaaaatgtcc gaccagatta tattgcagca ttctggaatg ttattaattg ggatgaagta
    13081 aacaaacgtt tcgaagcagc aaaataacca tttcctccgt catatcagtc ttaaaaataa
    13141 tttggaaaat aaaagagcga aagcttgcta gcgttttcta aattgggtat aatgttcttg
    13201 caaggttact tgcaagaact tttttggagg atatacattt atggaacacg gaacggttaa
    13261 atggttcaac aatgaaaaag gatttgggtt tattacagta gacggcggag atgacgtatt
    13321 tgttcatttc tcagcaattc aaggagacgg cttcaagagc ctagaagaag gtcaagaagt
    13381 agaattcacg attgttgaag gtgcacgcgg acctcaagct gctgaagtga ctaaattata
    13441 ataatttgtt gaataaagac acgacttctt agagagtcgt gtctttttgt ctatttatga
    13501 agtttttaga ttttttggct aagtaaatgc atttgttcac ttgacatgtc ctaactaatt
    13561 atcaagcaag gaacattttc ttcgttagta atggatttta aagaaatttc agtttttgga
    13621 tgttgaataa aagaccattt gtgaaaccac tagtatacat actcattacc atgtcaattc
    13681 tattacttta aaagaaaatc gttttacttt gaagaggagc atatctatcc attaaaagat
    13741 gatggtaatg caatcactag ttcgagtcat tttaagagcc atgcagtgag ctggaaataa
    13801 aacgaataga agatgggttt aacaaaagga ccagtcatag gaagaaattg tcgtgaaatc
    13861 gaatgataat ctgaacggta ggcaaagact gttaaaaaga tgggaaaggt atgtgcgatc
    13921 attttactgc acgattattt ggaaaatacc ttgttgttcg ctttttctgg aaaaaataca
    13981 taaaaaaaga taaaacgatt gcgaactgcg tgtattcggt ctttcgatct ttttcacggt
    14041 atggtatgat agttaagaat tttgagaaat tttaaaaaat aataatcgtt acacaaaaat
    14101 gttttttaaa gttttcttat gattaaaaag tgaatttgct gattgaacag ttatatgaga
    14161 caatatttta gaaaatgtga aacagaggtg tattatgaag cgatggcaaa aagttctatt
    14221 aaccttgtta ggggtattcg ttttgctgat tgccggatta tcagcatacg gaatcagatt
    14281 tatgggagaa gcgagccaaa cagtaaacaa aatttctaaa aactctaatc gaatatcctc
    14341 caaacgttct gagagagtaa gcattgatga caaagaacct ttttcggttt tgctattagg
    14401 tttagatacc ggtggattag gaagaacgga acaaggacgt tctgatacga tgatggtagt
    14461 aacagttaat ccgaaacaaa aaaaatcaac gatcatcagt ttggaccgag atatttatac
    14521 gaatatcgta ggttatggaa cggtagataa attaaatcat gcctacgcat ttggtggtgt
    14581 cgaaatggcc atggattcaa ttgagcaact gctcgatatt cctattgatc attatgtaac
    14641 gatcaatttg gatggcatgg aagatttgat caatgcggtc ggtggcatca aagtgaataa
    14701 taaaattgac tttactttgg atggtgtcca tgtaccagta ggtgaacaaa cattgaatgg
    14761 agaaaaaggt ttagcctatt ctcgaatgcg acacgaagat ccagaaggcg atatcggtcg
    14821 acaacgtcgt cagcgggaag tagtgacgaa aatcgtcaat aaagttttaa gtttagatgg
    14881 cgtaagcaat tatagaaaaa ttttaaaagc agttgagaac aatgtgacga cggacttaga
    14941 ttgggatgac atgcttgatg tagcgacgaa ctacaccccg gcgtttgaaa caatcaaaca
    15001 agaccagttg caaggcgaag gacaaatgat caatgatatc tactatcaaa ttttaggaaa
    15061 aaatgatctt ctttcgatcc aaaatgaact gaagaaacaa ttaaatataa aaacaagcga
    15121 tacattacct aatttgaaaa atgagaatgc ttcaatgatg ttctttgatg attcggaaga
    15181 tggcgattcg acaaacggtg atggatcgaa tagtgaaggg tacaccgatt attcttccta
    15241 ttcagaaaac acatatgatc agtaccaaga tccgaatacc tattatcagc aaacagaaga
    15301 tacaagtcag tactatacac caagtcaaga tactcaaagt tatgatcctt acgctggaca
    15361 ggaacaaaat ggttatggtt atgaccagaa taatgagtat ggaacaacaa gtgggtacta
    15421 gaaaaaaata gtttggttaa taaagagtgc cacctaaatt agacaaaaaa
//
LOCUS       DADGKS010000062        15317 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.062, whole genome shotgun sequence.
ACCESSION   DADGKS010000062 DADGKS010000000
VERSION     DADGKS010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15317
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.062"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..1609)
                     /locus_tag="JXV47_002157"
     CDS             complement(<1..1609)
                     /locus_tag="JXV47_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HAX1488176.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAK"
     gene            complement(1610..2011)
                     /gene="ftsL"
                     /locus_tag="JXV47_002158"
     CDS             complement(1610..2011)
                     /gene="ftsL"
                     /locus_tag="JXV47_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HAX1488177.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            complement(2016..2975)
                     /gene="rsmH"
                     /locus_tag="JXV47_002159"
     CDS             complement(2016..2975)
                     /gene="rsmH"
                     /locus_tag="JXV47_002159"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HAX1488178.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            complement(2996..3427)
                     /gene="mraZ"
                     /locus_tag="JXV47_002160"
     CDS             complement(2996..3427)
                     /gene="mraZ"
                     /locus_tag="JXV47_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HAX1488179.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            complement(3597..3965)
                     /locus_tag="JXV47_002161"
     CDS             complement(3597..3965)
                     /locus_tag="JXV47_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HAX1488180.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            4136..5092
                     /locus_tag="JXV47_002162"
     CDS             4136..5092
                     /locus_tag="JXV47_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAX1488181.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            5165..5281
                     /locus_tag="JXV47_002163"
     CDS             5165..5281
                     /locus_tag="JXV47_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HAX1488182.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(5336..7018)
                     /gene="recN"
                     /locus_tag="JXV47_002164"
     CDS             complement(5336..7018)
                     /gene="recN"
                     /locus_tag="JXV47_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HAX1488183.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(7036..7485)
                     /locus_tag="JXV47_002165"
     CDS             complement(7036..7485)
                     /locus_tag="JXV47_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAX1488184.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            complement(7592..8410)
                     /locus_tag="JXV47_002166"
     CDS             complement(7592..8410)
                     /locus_tag="JXV47_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HAX1488185.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            complement(8419..9309)
                     /locus_tag="JXV47_002167"
     CDS             complement(8419..9309)
                     /locus_tag="JXV47_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAX1488186.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            complement(9311..9535)
                     /locus_tag="JXV47_002168"
     CDS             complement(9311..9535)
                     /locus_tag="JXV47_002168"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HAX1488187.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            complement(9540..10877)
                     /locus_tag="JXV47_002169"
     CDS             complement(9540..10877)
                     /locus_tag="JXV47_002169"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HAX1488188.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            complement(10878..11732)
                     /locus_tag="JXV47_002170"
     CDS             complement(10878..11732)
                     /locus_tag="JXV47_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HAX1488189.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            complement(11829..12278)
                     /gene="nusB"
                     /locus_tag="JXV47_002171"
     CDS             complement(11829..12278)
                     /gene="nusB"
                     /locus_tag="JXV47_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HAX1488190.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            complement(12271..12696)
                     /locus_tag="JXV47_002172"
     CDS             complement(12271..12696)
                     /locus_tag="JXV47_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAX1488191.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            complement(12942..14006)
                     /locus_tag="JXV47_002173"
     CDS             complement(12942..14006)
                     /locus_tag="JXV47_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAX1488192.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            complement(14178..14423)
                     /locus_tag="JXV47_002174"
     CDS             complement(14178..14423)
                     /locus_tag="JXV47_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAX1488193.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            complement(14562..14936)
                     /locus_tag="JXV47_002175"
     CDS             complement(14562..14936)
                     /locus_tag="JXV47_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HAX1488194.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGNNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            complement(15019..>15317)
                     /locus_tag="JXV47_002176"
     CDS             complement(15019..>15317)
                     /locus_tag="JXV47_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="hosphoenolpyruvate-dependent sugar
                     phosphotransferase system catalyzes the phosphorylation of
                     incoming sugar substrates concomitant with their
                     translocation across the cell membrane; IID with IIC forms
                     the translocation channel; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PTS mannose family transporter subunit IID"
                     /protein_id="HAX1488195.1"
                     /translation="LPVVSTVKLDKGAYIEWDKLPSGGEGIKSAFEQVNNGLALSPEK
                     VTTLQDNLDQLIPGLAALGLTLLCMWLLKKKVSPIVIILGLFVVGVVGHVIGLL"
BASE COUNT         4306 a         3374 c         2517 g         5120 t
ORIGIN      
        1 tttttgccga tacattgtat ccaggtacac tatatacacc ataagcacta ccgtagtttt
       61 cgctttcgac aacatctctc atatattcac ggactttttc tgttgtttct tttgaaaaag
      121 gttgccctag aacttctgtt tgagttgttc gctcttctcc agtttgggga tccaccactt
      181 tgctgatata tcgaggttga atcattgtac cgttattcgc aatagaagtg aaagctttca
      241 tcatttggaa attcgtcaca cctaccgctt gtccataagc actcattgct cggtcgacaa
      301 tatttaatgt aggtaaagca ccgtttactt catcatctaa tccagaatga gtactttgtc
      361 caaatcccag tttttgtaaa tagttatacc atcgtccgcc taatcgctgt tccagtatga
      421 ccatcccgac gttacttgac catgaaagag cttgacgcat ggtcagcaca cctttttcac
      481 caaagtcatg gtcattgatc gtagcatctt ctacttggat ttttccagat tggaaggttt
      541 cattctcgtt gaattctcct tcttcgatag cagctgcagt agtgaaaact ttcatggttg
      601 atcctggttc ataactatct tgtaccaaga aattacgcca gatagcatct tttccagtca
      661 atccttccat tgtttcagga ttgaaagtag gtcgttgtcc cattgccaag atttctccgg
      721 tttttgcttt catcaggact gctgtcaatt cttctggctg atattcttca tttacttgat
      781 ccatcagtgt ttctaaataa ctttgtagtc tgctgtctaa agtcgtgtag atatcttgtc
      841 cgtcgacagc tttttcttct tctgccactg tacctggcag aggattttga aaattatctt
      901 tttgataaat aatcttacca tctttaccgc tcaagatatc attgtaagca gactccaaac
      961 ctagtttacc aactaagcca ttctcatctt tgtctggaac tgcgtatcca ataaaatgag
     1021 aagaaaagac gccatttgga tacatccgag cctgatggtc gacaaaataa agaccagcga
     1081 caccttcttt tttcatgtcc gcttcgatgt tttgcttggt ttcttgggag atatttttcc
     1141 catagctacc aaattcaact tgatacagct ctttttttgc gccgtcctct aaaatattca
     1201 gtgcatcttt tttgtctata gaaagattct tatgcaggat ttctgctatt ttatcaaaat
     1261 tcttttcttc aacatacagt tttttatccc cagaggtata tgtttttgag agtatcgctt
     1321 taattgaata agaggaggca tcttctgcga gcgccacacc gttacgatca taaatcgttc
     1381 ctctttttgc ttttactact tcacttcctt ggtacaactg ttttgttttt tcagctaatg
     1441 aggtaccagc aacatgacct ccaataacga tatacgagaa acggacggca aataaaaaga
     1501 acaatccaat actcgtagca aataaaatga tacctacttt tttgcgattg ttcatcggat
     1561 ttagattttt cttttccata aaccgccgaa ttttattttt aagactcatt tacttcactt
     1621 tccttaaatt gtcgtcatta atagacaatc ctttttcttc tgcgatttgt ttaatccgtt
     1681 cagtacgaga aagttcgttt ttttcttgtt ctaaactcgt tttttcttgc tttttatcat
     1741 tgatttctgt ttgtattgac gtgatttctt tttcagctcc gctgatattt gtgcgcagca
     1801 taactgttaa aacacataaa gcaacaatag caatcgccac gcttgccaca gcaatttttt
     1861 ccaaagcaga aatctgcttt aatcgttttg ccggtgattg tggaagaatg atttcttgat
     1921 tcgaagaaga atcaggcatt tgttgttccg gctgatccac caattcaggt aaatcatatt
     1981 cgtaatcttg cattttcttt aattctgcca tcattctact cctctttcat tcttattttt
     2041 tctgcaatac gtaactttgc actgcgtgat cgattgtttt ctgttagctc ttcctctgaa
     2101 ggaaggattg gtttacgagt aatgactttc agttctggtt ggaattcgtc aggtatgaca
     2161 ggaagtcccg gtggtagatc ttgtaccgta ctatattctt taaacatact tttgacaatt
     2221 ctgtcttcca atgaatggaa tgtgattacg ctgattcttc cattgacttt caataaccgg
     2281 attgcctgtt ctaaagaggc ctcttcggca ccgagttcgt catttactgc aatccgcaca
     2341 gcttgaaaaa ttctttttgc aggatgcccg ccttttcttc ttgcgggagc tgggatgact
     2401 tgtttaatga tttcgacaag ctcaccagtt gtttggattg gttttgtttt tcgtactcgt
     2461 tcgatttcac gagcaatttg tttggaaaat ttctcctcgc catagcggaa gaaaatcttt
     2521 actaattcat ggtaggaata ttcattaatt acgtgataag cggataaagg agctgactga
     2581 tccatgcgca tatccaacgg tgcatcttga tgataactaa atccacgttc tgcttcatct
     2641 agctgaggag aggaaacccc tagatcatac aaaatgccgt ctaccttatc tacatgctca
     2701 ctcaagcgtt cttctaattc tctgaagttc gctttgataa atgtgaccat accttgttcg
     2761 acataagaag ctaaacgcag cttggcgtga tcgattgctt tttgatcttg gtcaaacgca
     2821 tacagatgcc ctttagaact tagttggctt aataaatatt cactatgtcc ggcaccgccg
     2881 agtgtacagt ctacataaac gccatccggt ttgatgttca atccatctac cgtttctttc
     2941 aacatgactg tatagtgttg aaatgtttca gtcattagtc agcctcttcc tattcttata
     3001 gtccgaaatc aatcatactt tcagcaattt cgtcaaagtt ctcttctgct gctgcagaaa
     3061 aatcttgcca tcgtgtctca tcccaaattt caattcggtt agatacaccg atgactacgc
     3121 aaccttttgt caaagctgca taatttctta acgtgctggg tatattgatt cgtccttgtt
     3181 tatcaagttc gcattcagtg gcagccgaat agaagaatcg cacaaaagta cgtgcgtctt
     3241 ttttagccaa cggcatttcg ttcagtttag cttccagatt ttcccattcg ctcatcggat
     3301 agccgaaaag acagccatcc aatccgcgtg tcagaacaaa cttttcgcca agttcttcac
     3361 gaagttttga gggcacgatt aaacgtcctt ttgcatcaat attatgttgg aattcaccca
     3421 tcaacattga aagcccccca ttcctccact aactaaaatt agtctaccac aatcccccac
     3481 tttctaccac cttttctggg aaatccggga acaacttttt ttattcataa acattttttt
     3541 aaaaatcaag ctgcaaaaag ccttttaaaa gactttttac agcttttcta tttttttcat
     3601 aggtaagaaa gtatgttcac aatgatcaag acagcgtaca agacgattgt caacagaaaa
     3661 accaaacgcc aagtcatctt gaaataacgc ggataaataa tttcttcata ataatatgct
     3721 tggaaaacag caatacaaat tcccattagc aaaacagaaa taaagaaaaa cggtaagata
     3781 gaaattgtcc ctgtatttct agacaatgca tgcataccgc cccacaaaaa aggaatcgcc
     3841 aaatcagggg cttttatttt aaaacgacga tttaacgaaa ataattttac aagaaattgg
     3901 caaccaaaca aaacgattac cgggtaaata taccaaaaca agataagtgg tgtgaatgtg
     3961 cccatgaacg taaactcctt ttttatcgtt gcttcaagta tactgtatat actttacaca
     4021 actgtttcat tttatttaaa tttatgcagt tatattctat atcttacaaa cacattccat
     4081 gtattccaat tccctatccg ttataataaa agaaacaggc aacaggagga aaatcatgat
     4141 caaatatttt acattagata atgagaaact gcgtaatacc ggaaaggaaa ctgaccaaac
     4201 gatctggtat tgtgtagaac gtcctaatca agaagagatt catcagctga cacatcaatt
     4261 tgaaattccg tcagattaca tcacttccat attggacgat gcagaaaatt cccgtacaga
     4321 agaattcaat caatcaaagt tgacaaagcc agcgttatta ttgttacaat atccttttgc
     4381 taaaacaagt cctagcggtt attttcaagt ggatacatac ccgctctcta ttattttgac
     4441 gcccaaaaag aagcttatca caattacgaa tcatgaacca ctgtttttaa agaaagtctt
     4501 tagccagacc tttccaaaaa gtgatatttc gcctaatctc aatatcttct ttcaattcat
     4561 ttggcaggtc acactctctt acaacagtta tttagctacg cttcaatctc aatgcgatac
     4621 tttggaagcc aaacttcaag tatccactga aaacaaacaa ctttatcaaa tcatggatat
     4681 ccaaaaaagc ctcgtttatt tcagagaagc gacttctgct aatttagatg cattgaaaga
     4741 actagcgcaa aataaacttt tccaagaaaa tcatgctttg aaaaatcatt tacgtgatgt
     4801 attggtggaa acagagcagg caatgactac ttctcgcatt caattaaaac tagtagaaca
     4861 aatgaatcag actttttcag caatcgtatc gaataatctg aataatatta tgaaaatttt
     4921 aacttcttta acgattattt taactatacc gacaatcgtc ggcagtatct atggaatgaa
     4981 cattaagtta cctattgctg aaagggatga tgcctttata tggctagttc tattaacatt
     5041 atttatttgt atcgtaacta cctattattt aaaaaaaggg aagtttttat aaaaaagccc
     5101 tcttgtggaa atggaaaaaa gattgtacac ttgaatcaac taattaatga cgaggttgaa
     5161 aacaatgcgt gaaaaaaaac aaacaagtac ttttgctaaa gtaacaaaat ttgtcatttg
     5221 gacaatgctg attttaacga ttggatctgt tgtattgact gctgtaatga gtgtcatgta
     5281 aaaataaaat atagctatca gctgctgaaa aggacctgaa ccactgcgag gtggctcagg
     5341 tcctttttgc gagtttcaat agttcttttg catgttcgag tgtgagtttt gtaatctcac
     5401 ttccagccag catacgtgca atttcttctt ctctttcttt tgttttcaac tctgaaacag
     5461 aagtttgcgt acgtccatca atcactgctt tcacaatata atattgatag tcggcgactg
     5521 cagcaacttg aggcagatga gtgatgcaca aaacttgaga gtatttcgat atttgagaaa
     5581 ttttatctgc gatggcctgt gcaactcttc cgctcacacc tgtatccact tcatcaaaaa
     5641 taatacttgt cacaccttgc tcagaagaaa aaatagtttt caaagcaagc aacatccgag
     5701 acagttcgcc accagaagcg actttcacca aaggcttcag tggctctcct ggattggtcg
     5761 taatgtaaaa ttcgatttgg tcaaatccat catgattcaa ttgtctattt tcttctttta
     5821 agaaacgtac ctcaaactca gtgttttcca tatacagact tttcaattca tgcagaatgg
     5881 atttttccaa ttcttttgcg atttttttac gcgcttcatg aagatctgcg gcttgttgct
     5941 gaagtagaag ctctttttgc tctagttcct ctttcatttt gtccaattga ccttctgaaa
     6001 aatcagaaga agctagctct tcggtgattt cgtcatagta agccaatatt gactcaatgg
     6061 attcgccgta tttacgtttc aactgtcgga ttaattctaa acgttgcgta acttcttcta
     6121 aacgactctc atctaactcc aataaatcaa tctgacgact catatcgccg attgcatctt
     6181 gcagcaaata gtaagcactt tggatatttt cataaattgc ttcatactcc acatctagat
     6241 gggcgatccc ttgcagttct gaaacggcca agccaacacc atctacactg ttttgttcat
     6301 tattcgtcag tgctccgtaa cctgcagcta atccatcagc aattttttga taattgctaa
     6361 gtttttctct ttcttctttt aatttctctt cttctccgac ttgcaaatca gcagcagcta
     6421 tttcttcttg ctggaaatgg agcatatcta ttctctgaac ataggatttt tcattttgct
     6481 gcacttttcg tacccttttt tccagctcac gataagagat atattcttgc tgataactct
     6541 ttttcttctg ttggaaagct acatctccaa aacgatccaa taaagcaaga tgtgattcag
     6601 gctggagcag ttcctgatgt tcgttttgtc cttggatatc tactaaataa ctgccgattc
     6661 ttctcagatt agctaatgtg ataatatgac cattcactcg acaaacattt tttccagtta
     6721 aggacatatc ccgtcgaaca atcagattgt cctcatctgt ttcgatccct aattcaacca
     6781 tcagttcaga gaatccttct tgttttggta gttcaaacaa cccttcaagc acacattttt
     6841 ctgctccttg acgtatataa tcgcttgaac ctcttcctcc tgctaacaga cctaaagcat
     6901 cgataataat ggatttaccc gcaccagtct ctccggtcag cgcggtcatt ccttcgtgaa
     6961 aagaaagccg caattccgga ataatcgcaa agttagtaat actgatttct tgtagcatca
     7021 cattcgctcc tcaacttaaa ggtaatgcag gaagtctttc ttcaataaaa ctgcctggtc
     7081 ttcagttcgt gtaatcatca aaacattatc gtcatcattg ataatcgaaa ataattcttt
     7141 cttgtaacgt ttatcaatca aatttgctgc tgccgaagca tttcccggca atgttttcaa
     7201 aataacaaat ttttccattt ggtcaactgc cacgaaagcg tcttttaata gtttttccaa
     7261 tttagtattt acatcttcgt ttgtttcagc tggtatgcta taacggtagc cgccatctga
     7321 agccggtacc ttgatcagtt tcagttcctt tatatctctg gaaatcgtag cttgagtaac
     7381 agatattcct ttgcttttca ggatttcaac aaattcttcc tgctttcgga tatcttgctc
     7441 actcaacaat cgagtaatca aacgatgccg atcttttttt ctcattacgt cttcgctcct
     7501 tagcatattc ttcttaatca atgatagctt atttccttgg tataataaag aagaatccgc
     7561 atacttctca cttgattttc acagttacaa tttatttatg gtcaaactgt tcgtgtgcat
     7621 ttgaaaccac ttctgccata ttaatagctg aattgattgt tccgctttcg ggtactttcc
     7681 tcaagtgagc caagaactcg atatttcctt ctccccccgt gatcggagaa taacttaatt
     7741 ccagcacatc atatccacct tgtgccgcaa atgacaaaat gtcttctaaa actttttgat
     7801 gggtctgagg gtcacgaaca attccgtttt tccctacagc ttctctgcct gcttcgaatt
     7861 ggggtttgat taaagcaatc acttctccct cttcttttaa aatagcatgt aatggaggca
     7921 gcatcagttt tagtgaaata aaagaaacat cgataacagc aacttctgga attcctaagg
     7981 taaagtcttc gggttttgca taacgaaaat tcactctttc cattacgacg actctaggat
     8041 cttgtcttat tttccaagct agctgattgt agccaacgtc taaagcataa ctcatttttg
     8101 cgccattttg caaagctgca tcagtaaatc cgccagtgga tgcaccaata tctaacaatg
     8161 tttttccttc aacagataga tcaaatgctt tgagtgcttt ttctaatttt aatccccctc
     8221 gagaaacata aggaagtttt ttacctttga ctcttaattc actactcact ggaatttttt
     8281 ctcccggttt atcaaaccgc tcgttttttt cgttgtaaat caaaccagcc atcactgaac
     8341 gtttggcttg ttctcttgtt tcaaataatc cttgtttgac cgctaataca tctacgcgtt
     8401 ctttttccat tctttccctc atttctccac atcaaattgc ttgatcatct ggcgcatcag
     8461 cccgccatca aaagaaaaaa cgtcctcttc taatttgtct atgatcttgt tggcggataa
     8521 cagctcaatc tccaacgcct cacgtgtctt ttctaggcct aataaacgcg ggtaagtatt
     8581 tttttccata cgttcatctt taccagctgt tttccctaat gttttcgttg taccaatcac
     8641 atcgagtaga tcatctctta tctgaaaagc taaacctaaa tgttcggcta atcgttgaag
     8701 tagcaataag atttcttcag gttgcttcgc taatatgcca ccagccagca aggcataacg
     8761 aatcaaatgc cctgtctttc tttcatgaat aaatgctaat tcttctaaag aaagcttttt
     8821 cgattcgccc tcgatatctg cagcttgccc agcaaccata ccttgtgatc ccgcacaaac
     8881 agctaattgc tgaagcagca gaagcttagg agaattacct aagtgtgcca tactgattag
     8941 ctggaatgct cctgtaagca aaccatctcc ggccaatata gctaatgctt cgccgaatac
     9001 tttatgattg gtaggttttc ctctacgaag atcatcattg tccatcgcag gcaaatcatc
     9061 gtggatcaag gaatacgtat gcaccatttc taaagcagct gctacttgat agacgggaac
     9121 atcaataggc tcatcaaagg aagcaacggc cgttaaaagt aataagggac gtattctttt
     9181 cccgcctgct ttcactgaat aactcatcgc atcatagagt cctctatccg ttgtatgctc
     9241 atctaaaaaa gacaagattt ctttttctac agcaggtaga tgaatagctg aaaagtcagt
     9301 taatctcatc tcagctttcc tcgtttccgt caaaatcaac ttcttcattt gattctgtca
     9361 tcattttcgt caaggtctct tctgctttag ctaatgtatc ttggcaatgt ttgcttaatt
     9421 ccattcctcg tttaaacgaa tctagagctg attctaatgg aacgtctcct tgttctaact
     9481 gcatgacaat tttttctaat tcttgcagtg actcttcaaa agttggattt tccatatttt
     9541 tattctcctt tgtctatctc ttgtacttgt cctttaacga ttccatcttg ataatggatc
     9601 gtcagcaaat ccccttgatg aatctcggtg acacttttta ctacttgatc atttaacgtc
     9661 gtatagctgt agcctcttcc catgattttc aatggactca acaaatcaag agattgaaca
     9721 gcttgagcaa aacgctgctg ctgttgtttc atatattgtt ggattttctc ttctaagcgt
     9781 ttttctagat aagcagtttc ttggcgagct gctttaactc gataaagcgg agccacttgt
     9841 tccaattggt ggcttaatgc gatcgtttgt ttttctttcg catgataaat ttgctgtgta
     9901 gcttgatata atcgctgttt caactggtct aatttgatgg tctgaccttc atacaatctt
     9961 tcaggctgcc gaaatacata ggaacgtcga gcacgctcga accgttcttg tttgcgctgg
    10021 atctggcgta caaacgcctg ctgcaatcta gcttgccgtt cttgaatgcg catcaactct
    10081 tctgacaaaa caggaacagc taattctgca gctgctgttg gagtggcagc ccgaacatct
    10141 gctactaaat cagcgatcgt ggtatctgtt tcatgtccta cagatgaaat caccggcgta
    10201 ttagcttgat aaatcgcccg agcaacccgc tcttcattaa acggccataa atcctcaatc
    10261 gaaccacccc cacgaccgat gatcattgta tcgaaattgc ccatctcttc tactctctgg
    10321 atattcctga caacattgtc cgctgcttgg tttccttgta caactgttgg gaacaaaacc
    10381 aattggacaa ttggatatct tcttttcacc gtcgtgatga tatcgcggat aaccgctccg
    10441 cttggactgg taaggaccgc gattcgcttt gggaaacgtg gcagcatttt tttaggccct
    10501 tgaaaaaggc cttccttcat cagcttttct tttcgttctt ccaattcttg atataaagca
    10561 cctattccat caggctccat gtgctctaca tagatttgat aagaacctcc cgcttcatat
    10621 aatgaaatac gcccaacgac aaggactttc attccttctt ttggctggaa tcgtaatttt
    10681 tggaatgctc ctttgaacat aatagcagat atttttgcat ggtcatcttt taagctgaaa
    10741 tattgatggg cattggcacg taaacggaaa ttcgatattt cgcctgttaa atatacgcgt
    10801 tctaaataag gatcggcatc aaattttctt ttcaaatact tcgttaatgt agtgacagtt
    10861 aaatattctt gtgccatcta ttcacctgct ccaaaagctt cggcagattt tacggtttga
    10921 tacatcagca tcgtgatagt cattggccct acaccctttg gcacaggagt gatccagcct
    10981 gcaataggct ccacttcatc aaatttcaca tcaccgatca gcttaccgtt agcatcacga
    11041 ttcatcccta catctatcac tacagcacct ggttttacga attcttttgt gacaaaatgt
    11101 ccacgtccta ttgctacgac taaaatatct gcttcttgtg ccagttcagc cagattttcg
    11161 gttttagaat gagcaacagt aacagttgca tctgccatca agagtagctg agccatcggt
    11221 ttaccgacga tattgcttcg tccgataact actgctcgtt tacccgccgg atcgatagaa
    11281 taagcttcaa acattttcat gatgccgtat ggagtacaag gaatcttgtc cggtttaccc
    11341 gcaaggagtc tgcctaaatt catcggatga aaaccgtcta cgtctttttc agggcggata
    11401 gctaacagga tcttttcttc atctatatgc tttggcaatg gtaattggac caatatacca
    11461 tgaaaactag gatcttgatt gtatttttca atttctgcaa gtagttcgtc ttcagaaatc
    11521 gtctcaggat aacgctctac caatgaatgg attccgattt cttttgctac acgttcttta
    11581 tttcttacat agatttggct ggctggattt tcccctacca ataaaacgac taatccggga
    11641 tggataccat tatctttcaa tttttggatt ttttcagcaa tctctgcctg cattttttca
    11701 gctaattctt ttccgttaat caattctgcc atctaaccac tcccagatat tttttgtgtt
    11761 ttcattctac catagaattt tcccgattta taacaggttt atgatgattc atagaaaaaa
    11821 gctaggactt acgccccagc ttctaattct ttcaatacat tggataaaac accgttgacg
    11881 aatttacgtg aacggtcatc actaaatgtt tttgccaact cgattgcttc atttaaagca
    11941 acagccgctg gtacatctgt cacataagtc atttcaaaaa tcgcgatacg caagatcacc
    12001 aaatccattt ttgagatccg attgatgtgc caattgtttt ttaaatgttt ttcaatcact
    12061 ttatccaatt catctttttt tgcacagaca ccgccaacta gcgtatcaag ataaacagga
    12121 acaaactctg attcatcttc gttgatcatg tcgcggtggt ctaattcgat tgcgttgaaa
    12181 atcgcatctt cttttgttag gtctgcattg aagtctaatg gaaataaagc ctgcaatgcc
    12241 atttcccgaa tctcgtgtct tgataattct ttattcattc tcttcctctt cgtcttcaaa
    12301 aagttcttcg attgttggtt gttctaattt ttcaggaaca acagctacta catggatatt
    12361 gacttcagat aaatcgatat ccgtcatgaa aaggacttgc tggctgaccc gttcctgcat
    12421 ttccattgct actttaggaa ctgaaacacc atattctaga taacagtaaa gatctacttt
    12481 caagccatct tcctcgtttg ctaagtaaac accttttccg tgagctgcac gtcctaataa
    12541 ttcagtgaca ttgctggcaa aagttccgcg cattccgtat acgccttcta ctttagaagc
    12601 tgcaatcccg ataattactt cgatgacttc aggagcgatc acgatctctc ctaaatcttg
    12661 gtttgcgttt aaaatcaaat ttttttcatc tgccatttat ttattcctcc ctttgcctaa
    12721 gcacgagata catccgaatt ctctatgatg cggcatagtg atcacgtggt aagaaaactg
    12781 ccgccgatca gctgcaaact gctatgaatt ggagaaaaca cccaacttta ttatctctta
    12841 cagcttaaaa gttcttctat agtgtatcat taaatcgagt gattttctat aacaaagtct
    12901 gtgaacactg atttttacgc ttacttcttc tattgatgaa actataagat gatcaattct
    12961 tttggtgaac gagtcaacac acgatttcca tcttctgtga tcaacaagtc atcctcaata
    13021 cgtactccac cgattcctgg taagtagatc cctggttcat cagtgatcac atttcctggt
    13081 acaaattgct tttctgcacg agaagaaacg tttggtcctt cgtggatctc taaaccgatc
    13141 ccatgtcctg tagaatgtcc aaatgcttcc ccgtaaccat gttttgaaat ataatctcta
    13201 gcaactgcat ctaattggac accagtcatt cctggttttg cagcatcaat aactgctaat
    13261 tgagcatcta agactatttg ataaatttct tttaattttt ccccaggatc accaatagcg
    13321 aatgtacgtg tcatatcgga aacgtaccct tcgtaatagc aaccaaagtc caatgtgatc
    13381 aagtcacctt gttcgatgat ttttttgctt gctacaccat gcggcatagc cgaacgcaat
    13441 ccgctagcaa cgatcgtatc aaaagaaaca cctgaagcgc caagagaacg catataaaag
    13501 tctagttgat ttgcgacttc aatctcagtc atgcccggtt ggatcatttt caggatgtga
    13561 tcatatgcca tatccgcaat atgacatgct ttttcgataa tagcgatttc ttcttcatct
    13621 ttcacttctc tgagttcttc gatcatctgt gaaacaggta ctaattccgc atcgatgatt
    13681 tcttctaaaa ccgaatattc taaaaatgag actgttgttt cctcaaaagc taatgagtgc
    13741 agttcttctt tgcgtactaa gtttgctacc tcatcaaaaa taggtccgac atttttaata
    13801 atttcaaacc cttgagcctg cgctgccgcc tgctcggtat aacgaaaatc agtaataaaa
    13861 aatgcttttt ccaaagtaat aacagctaat cctgtcgtac ctgtaaagtt cgttaagtaa
    13921 cgaagattgt acggactggt aaccaaaaat gaatccaaat tttcttcttg catttttttg
    13981 cgcaattttt ctacacgtag catcataatg aaactccctc tttctttgca cgcttttttc
    14041 cattatagca aacttttctt cgtacacgac agttaaataa aaatttccgg aaaacttctt
    14101 tttattttaa ataaataaag ccaaaaagga gtcacagtct cgctgcaact ccttttagtt
    14161 tactattttg taaaaactta tgatcgtttt ccaaagaaaa atgagacaac tgctaccaaa
    14221 atcactgcgc ctaaaataga tggaataagt gccatacctg cagcttttgg tccccattcg
    14281 ccgaaaatcg cttgtccaat acttgaaccg actagtccag caatgatatt cgttacacag
    14341 cccatcgaat ttcctttact ggtgatcgca cctgcaattg ctccgatcac ggctccaaca
    14401 atcaatgtcc ataaccaact cataatataa cctccttctt tgctaatcaa ttttagcata
    14461 tgggatttaa aggggacaaa taattggttt tgctatttca tattttcttc tgcaaagtaa
    14521 aaaaataaag aaaacctcct cttagaagtt ttctttattt tttacttgcg tttaaacata
    14581 ctacgaatac cacgtttcac tacatcaaag aaactcaatg attgtaccat tctatcttca
    14641 tctacatatt ctctgatcgc acgaagcact tttttaggtt ctttggaaga aaatgtgtat
    14701 gtaccatttt ttttcgtttg aatggcatat cgaggaatcc attttccctt tagcatgact
    14761 gatgctagta cataatccac ttcttcccat ggaatttgga tatatttgcg tctatctcgc
    14821 gcatggtaaa actcaaaacc attattacct atcatgattt gcccgtaatc tgtcagaccc
    14881 gtaaacgaag tagcatcaat taccaagtct acttttgtat tgattgattg aaccattttc
    14941 tccctccaga tatttgttta tgaacagtat actatataaa aaaagctcgg gacaacgccc
    15001 gagctatatt tttatggatt ataaaagtcc gatgacgtgt ccaacaacac cgactacgaa
    15061 taaaccaagg atgataacga ttggagaaac ctttttctta agcaaccaca tacataacaa
    15121 tgttaatcct aatgcagcta aaccaggaat caattggtct aagttgtctt gtaatgttgt
    15181 taccttttca ggagaaaggg ctaagccatt attaacttgt tcaaatgcac tcttgattcc
    15241 ttcaccacct gaaggcaatt tatcccattc gatgtaagca cctttatcta attttacagt
    15301 tgatacaact ggtaaga
//
LOCUS       DADGKS010000063        15229 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.063, whole genome shotgun sequence.
ACCESSION   DADGKS010000063 DADGKS010000000
VERSION     DADGKS010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15229
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.063"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            278..786
                     /locus_tag="JXV47_002177"
                     /pseudo
     CDS             278..786
                     /locus_tag="JXV47_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
     gene            879..2041
                     /locus_tag="JXV47_002178"
     CDS             join(879..1155,1155..2041)
                     /locus_tag="JXV47_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAX1488196.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLIPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2321..3301
                     /locus_tag="JXV47_002179"
     CDS             2321..3301
                     /locus_tag="JXV47_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAX1488197.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3423..4841
                     /locus_tag="JXV47_002180"
     CDS             3423..4841
                     /locus_tag="JXV47_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HAX1488198.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4912..6381
                     /locus_tag="JXV47_002181"
     CDS             4912..6381
                     /locus_tag="JXV47_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1488199.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6391..6858
                     /locus_tag="JXV47_002182"
     CDS             6391..6858
                     /locus_tag="JXV47_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAX1488200.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6894..7766
                     /locus_tag="JXV47_002183"
     CDS             6894..7766
                     /locus_tag="JXV47_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAX1488201.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFIKSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7847..10381
                     /locus_tag="JXV47_002184"
     CDS             7847..10381
                     /locus_tag="JXV47_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAX1488202.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDRILKECAGSSEYNYLESD
                     EFIALRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFR
                     MKNDKQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITAS
                     AIARETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQM
                     YEKIESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLS
                     QKKNVIVSCLSGEGISEKVKDILKRYLDNQVEILIFDFNALKKIAKEKDTMIFKNTIC
                     VLSTTEFYIQGIDCLNLENLINGNQTLEKLNKYMDSDSCEFCLNELVKLFTIEGASTK
                     LRFLDSKKVFNEIEKVLYLYEKYYDVKIPSFLRINLFLHLSGMIERIMIGDGITNEHL
                     KEGAQLFDTFLNVSKDFFSEIKDIYCIEIPKGEYELIYTIFEQTIF"
     gene            10537..11310
                     /locus_tag="JXV47_002185"
     CDS             10537..11310
                     /locus_tag="JXV47_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1488203.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            11303..12094
                     /locus_tag="JXV47_002186"
     CDS             11303..12094
                     /locus_tag="JXV47_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAX1488204.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            12104..12595
                     /locus_tag="JXV47_002187"
     CDS             12104..12595
                     /locus_tag="JXV47_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAX1488205.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            12613..13023
                     /locus_tag="JXV47_002188"
     CDS             12613..13023
                     /locus_tag="JXV47_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAX1488206.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            13027..14427
                     /locus_tag="JXV47_002189"
     CDS             13027..14427
                     /locus_tag="JXV47_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HAX1488207.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            14450..14824
                     /locus_tag="JXV47_002190"
     CDS             14450..14824
                     /locus_tag="JXV47_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAX1488208.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
BASE COUNT         5286 a         2134 c         3046 g         4763 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat agccctaaac
      241 aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa tagaaagagg
      301 tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca tcaaagtaaa
      361 taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc taaaactcag
      421 tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta gtattacgga
      481 attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc ccactttaga
      541 gaaaatgaat cttataagca tttctcaaaa aaaggaaata agaaaactaa acttgtatcg
      601 ttaacaaaat atggtcgaaa ggtgtacgaa tcacataatt atttacatga agagctttat
      661 agctcaataa atgaagcgtt agaatcattc tcaccagacc aaatttcaac cattaaacag
      721 attctagaaa aagtatctta tacaatcaat gaatatcaag taagtctgac aagaaaggaa
      781 gattgacatg aaaaaaatga tttttgaatc ggctacacta gactagacag aaaaaataag
      841 gtgtgtaaaa taaatgaaaa cacactggag gaatttttat gtcaagacgt caacgtagaa
      901 cctattcaaa agaattcaaa caacaagtcg tcgatcttta tctcgcagga aagccccgag
      961 ctgaaatcat tcgagattat gagctgacta cctcggcctt tgataagtgg gtcaagcaag
     1021 cgcaaactac tggctcgttt caggaaaaag ataacttgat ccctgaacaa gtagaactaa
     1081 ttgcattacg aaagaaaaat aaacagcttg aaatggagaa tgacatttta aagcaagcgg
     1141 cgctgatatt gggacgaaaa gacaagtaat tgataccaat aagcacaaat actcaatatc
     1201 agcgatgtgt aaagtgttaa acatctcttg ccaaacctat tattatcaag ccaaaccagt
     1261 tgaagatgaa tcagaactgg aagaactcgt tcaagaagaa tttattcgca atcgaaaagc
     1321 ttatggtacc aggaagctga agcagtgctt ggccaatcta ggtcttcaag tgagtcaacg
     1381 cagaatcggc cgtatgatga aacagcgtgg cttgcgttca acatacacat tggctcattt
     1441 caaattccat tcttctactt gtaacgaagc caagaccgcc aatattctag acggaacctt
     1501 cctacaggaa aagtcattag aagcgattgt aaccgacctt acctatgttc gtgttgggaa
     1561 gaaatggcag tatatctgcc tgattcttga tttgtttaat cgagaaatca tcggctattc
     1621 atgcggggag aagaaagatg cgacgttagt caaggaagct tttgcaaaga ttccgtactc
     1681 gttgaataat gtacaacttt ttcacacgga tcgtggaaaa gaattcgata accagacgat
     1741 tgacgaaatt ttatgggcct ttaatatcac gcgttcctta agcaaaaaag gctgccccta
     1801 tgataacgcc gttgcagaat ccacctataa atctgtcaaa gtagaattcg ttcatcaata
     1861 ccgctttgag acattggcta atttgcgatt agagctattt gattacgtcc attggtggaa
     1921 taccatccgg ctgcacggca cgttaggcta tgagacaccg atcagttttc gacagcagag
     1981 attggcgcag cgaatccttg ataatgagct cggatgtgat accggtggcg aggcacctta
     2041 attatttgaa tgagcttctg ccttagagaa tcagattcga ggaggctcgt tgtcaagggc
     2101 agtcggaaca ccagcagcaa gcttacgcaa taccttataa tttttgtcaa aaaaagtgtt
     2161 gccattccac atatatcttt aaacagctat tgccagataa aaataaatga tattatatat
     2221 ataaatactt atccgaaaag gggaatgaga gagtcaaggt tcttggaatg tcgaatagtc
     2281 gagtaggtag attttctatc tacaaccttg ttgtttaaaa atgaaaaaaa ttggaattag
     2341 agaagttgcg aaagaggcaa atgtttctcc tacgactgtg tcgagggtat tgaatgatcg
     2401 tggatatttg agtgaggaaa caaaaagaaa agtttttgat gccatgaaaa aattagaata
     2461 ctatcctaat gaactggcga gagcactttt taaaaacgaa acatataccg taggtttgat
     2521 ttttcctaca attactaatc catttcacgc tgagttaatt caagatatcg agttcgagct
     2581 ttccagcagg ggatataaag tgttgctgtg caatagctta aacaatccaa caaaagaaaa
     2641 agagtacttg acgatgttga gaaagaatca ggttgatgga attatagtag gaacgcacaa
     2701 taaagatatt gcggattatg atattccagg gctacctatt gtagcgattg atagaagtct
     2761 tggtgaaaat acagttacag tatcttgtga taattacagg ggtggggaat tagctactca
     2821 actacttgta aatcatggct gtcagaatat actgtgtatt cggggagata gtaagataaa
     2881 gctacccgcg aatagtagga ctttagcata taaagatgtt ttgaataaat tcatgctgga
     2941 accgttagtc ctagaagtac catttgtaaa agaaatcaat gaaaaaaatg aaataattaa
     3001 gacatatctg gaaactcatc caaatattga cggggttttt gcaggagatg atttattggc
     3061 ttctttggcg attaacaact taggaagttc gggcaaaaga gttccaaaag aggttaaagt
     3121 gattggattt gatggagctc aacaaacatt gatttataat ccagaattat caactattca
     3181 acagcctata gatcaaatat ctaaagtagc agtaaaaaaa ttattgaata tgattaaggg
     3241 cgaaaaggag acggatgaac tttcacttcc agtaaagctc ataaaaaaaa atacagcata
     3301 agttaaatcg gcgaaaaatt ccttcgtcga tttaaaaata tttttatgaa acgggttgac
     3361 atatgaaacg ggttgacata tattagttgt gaagataaaa accttttcac tggaggaaga
     3421 aaatggagaa attattaatt aaaagcaata atcatcaact ttactaccaa cctaaggatg
     3481 tttgggtcgg agatgttatg ccttacggga aagaaggaaa attctttatt tatcatcaac
     3541 gtgatactag aaatccagtt ccttttggag aaccgtttgg ctgggcttta gcaactacga
     3601 aagattttgt tcattttgaa gactttgggg aatctctttt aagaggggat gacaatgaga
     3661 gagaccagtt tatctacgct ggttctgtat ttgaggcaaa tggaaaggtt cacgcatttt
     3721 atacagggta taatcgtgaa ttcttagcgc agggaaagac atctcaagtg ttgcttcatg
     3781 ctgagagtga tgattttgtt cattgggaaa aatcagaaac agcattggag ttagaaccac
     3841 aagaagggta tgatattcga aactggagag atccatttgt cgtttgggat gatgaaaaag
     3901 aagaatattt gctaatttta ggggcgcgaa agggtcagga taaacatcta caaaccggac
     3961 gtttagtgga atttacatca aaagatttaa ctaattggga attcaaaggt gatttttggg
     4021 ctccgggatt gtataccatg tttgaaatgc cagaactttt caagattggt gactggtggt
     4081 atcttgtcta ttcagaatac tcagatggaa ataaaatact ctatcgaatg agtcaaagtt
     4141 tggaaggtcc ttggattaag cctaaagatg aagcttttga tggacgggct tattatgcag
     4201 gtagaacagc ttatgatgga aaacgtcgag tcctatttgg atgggtacca acaaaagatc
     4261 aagaaaatga taaaaacaat tatttatggg gaggtacttt ggttcctcat gaagtctatc
     4321 aaaaagagga tttttcactt ggggtaaaac ccatagacga agtgtggaat gcattcataa
     4381 atttacatga tattgccgat gtagagatag aaacagcaga cacaagagaa gaagtaacgc
     4441 ttgtcaaaaa tagtggaact ttgtttaatt tagaaacaac aatttcattt gatgagaatc
     4501 ttagtgactt ttcactgaga ttatataaaa accttgagac agatgaatct tacgaatatc
     4561 gcttcaattt agatgagggg cgtcttacat ttgataaaaa cccttgttac ccttggtttc
     4621 aatatatgga taaaggactt attagaccta tatctttaaa gcctaaccaa tcttataaac
     4681 taaaagtgat tgttgatgac aatataatga cactttatat tgatggaatc gctcttaacg
     4741 ctcgtgtaca tggttgtttt ggtcaagcaa ttactattac agcaacaaat ggatcaatga
     4801 ctgcaataaa taccaagttt tcaaatgaaa taaagaaata ataaacgtca atcatgtggc
     4861 aggtctgaaa atcaaacatg acctgtcaca tttaaaaggg aggataaatg aatggactac
     4921 aaaaaaattg ccgaagatgt attggaaaac gttggaggaa aagagaatat ctcaagcgct
     4981 acacactgca ttactcgttt acgtttaatt cttaaagaca aaagcaaagc gaatatggaa
     5041 atgcttgagg aaatagaagg tgcaaaaggt gttcttttca atagtggaca gttacaagta
     5101 attttcggaa caggtataat tgaaaaggtt tacaaagagt tcgttgaatt gacaggagct
     5161 aaggaagtat ccgtttctga aatgaaagac gaaggagtca ataattcagg aaatagactt
     5221 caacgagctt ttaaagtttt ctcggatatc tttattccga tcattccagc ttttattggg
     5281 gcagcaatgg ttttaggaat tcgttcgttg attaccactc ctggaatgtt tggaatggat
     5341 ggctcattcg ctgatcacaa tgtattccta aatgatttat ccaaatttct gggtattatt
     5401 gcaaccacat ttgattattt accagtttta gttatgtatt ctgcaacaaa acgttttggc
     5461 ggaaacccta ttttaggatt acttgtagga tttgttatga ttcatccagg actagccaat
     5521 cggaatgatt tcgtcatggg aactataaag cctgattatt ggcatttatt tggattaagc
     5581 attccagcag ttgcgtttca agggggtgtt tttccagcaa ttttgacttc ttggttttta
     5641 gcaaaagttg agaaaattac aaataaatat tctcctcaag tacttgctta cattttagtc
     5701 ccaactgtga caattgttct tgccaacttt gcactatttt tagtgtttgg tccattgggg
     5761 aattttatcg gtaatgtttt aggtggaatc attgatttcc tatatatgaa gatgggtgcc
     5821 tttggtgctt ttgtttttgc aggcgcgtta caaccattag ttgtaacagg aacacaacat
     5881 gctattcaag gtattgaggc aaacttagtc gcaacaactg gattcaatta tatccaacct
     5941 atttggtcag tttcaattat tgcccaaggt ggcggttgta ttggtatgta tttactcttt
     6001 aagaaaaaat ctaaagatag agatattgcg atttcaagct ttattccaac actggtaggt
     6061 attactgaac cggctatctt tgctgttaat ttgaaatatt caatcgttcc ttttgtttgc
     6121 tcgtttattg gtgctggttt tggtggagca tttatgaaaa tttttgatgt aaaagccatt
     6181 ggacaaggat tgactgtatt gccaggtctg actattgcta atccagttct tccttatata
     6241 tttggtaatc tcatagcatt cattttacca atcattttta ttctcgctta tgataaatat
     6301 aaagtgttta tccctgaagc taaacaccgt aaatttgcag aaaaaactga ctcaaaaaaa
     6361 ttgccagttc aagtaaagtg agatgagagc atgttaaatt tttttagaaa aaatgaaata
     6421 agcgttgtag cacctgcaac cggtgttttt gaaaaactgg agaaattaag tgatccagtc
     6481 ttttcaaaag gaatgatggg acaaggattt gcaattgatg caaaaaacga aacgattgta
     6541 tctccaatcg atggttttgt ttcaagtatt tttcctacaa aacatgcctt aggaataaaa
     6601 acaaaatcag gaattgagat acttgttcat gtaggaatag atacagttga gctaaatggt
     6661 gagggatttg atattaaagt tcaagaagga caaaaagtta aggctgggga tattcttatg
     6721 accattaatt ttgtagtttt tgaaaagaat cacaagacta aagatgtcat tgttgttttt
     6781 ccagactacc aagacgaaat tttcattccg aaacttgaag aagtaaaaca aggacaagaa
     6841 ttgtttgttc ttggctaatg ataagtaatt aataatagaa tcgaggaaaa tgtatggttt
     6901 ttggggctat tgaagctggt ggaacaaaat ttgtttgtgc cattggagat aaagatttga
     6961 acatatttga aaaagtcagc tttcccacga ctacacccaa agaaacaatg aatttagttt
     7021 tagatttttt taatcatcat aaagatgatt tagaaggtat cggagtggga tcgttcggtc
     7081 ctattgatat tcattgtgaa tctaaaacgt atggcttcat taaatcaacg ccaaaacttg
     7141 cttggcagga ttttgatttt attggaagtt taaaaaagca acttaatatt ccaactgctt
     7201 ggacgactga tgtaaatgcc tcttgctatg gtgaatatgt ttctggaaat ggcagaggcc
     7261 tttcaagtgt tgtttactat accgtaggaa cgggcatagg aggtggcgct atccaaaacg
     7321 gaaacttcat tgaaggtttt agtcatccag aaatgggaca tatgcttgta aaacgacaca
     7381 ataaagacaa cttttctggg acatgtccat tccacggaga ctgtttagag ggcttagctg
     7441 ctggtccggc aatcgaaaga agatcaggga aaaagggaca agaagtgact gaaaatgacg
     7501 ttacttggga aatagaagct tattacattg ctcagtgtgc atataataca acattgatgt
     7561 tatcacctga tgtcattata tttggtggcg gagtaatgaa acaaaaacac ttaaaaaaga
     7621 aagtacaaga taagtttatt gagttgatca acggatatgt cgctattccc gatgttgaca
     7681 attatattat gacaccaaaa ttgttagata attctggtat tgtaggttgt ttagctttag
     7741 caagagacgt taaagaaaaa tcttaatttg gaaaaaagat cgtctcgact atttgtttgg
     7801 ttgatgcgat ctttttttca attagtaatt gaagggacgc ctaaaagtga aaaaaaaaat
     7861 gaaagatgaa gtattagagt atatcaaaaa taatttaaag tattacgatt tttctgctca
     7921 agatattgca atgaaatttt gtattaaaag aaatgtcgct tcccactatt tgaatcagtt
     7981 attttcagat ggaaaattac taaagaatga ttctgttaga ccagtaatgt tcaagtataa
     8041 tcaacaaaag ccaaaagact gcttttctaa gtttattgga gcagacatat ctttgaaatc
     8101 cactatagat aaatgcaaag ctactgtaat gtatccccct aatggcctcc cattaataat
     8161 aaaaggaaac agtggcgttg gaaaaagttt tttagcaagt ttgatctatc agtatgctct
     8221 tgatagaaaa gtaattcata atgacgcaaa atttgttgtt gtgaattgtg cagattatgc
     8281 aaataatcca gagctattgt cagcagtttt atttggatat aaaaaaggag cctttactgg
     8341 ggctgaaaaa gatactgcag ggatgctatc ttctgctaat ggaggatacc tttttttaga
     8401 tgaggttcac aatctaagtg cagaaaacca agagaaattg tttcttctta tggattctca
     8461 aaagtatcgt aaacttggtg aaagtgtgca atgggagtat gcaaatgttc gccttatctt
     8521 agccacaaca gaagataaaa atacctcttt gttagcaact tttagaagac gcatcccagc
     8581 tgaaatcact ctgccagatt acaataatag aagtacatct gaaaaaattc aattattatt
     8641 tgaatttctt aaagatgaag caattacgat tgattcaaaa atattttgtt cgattgaact
     8701 ttttactgat cttttatcga aaacatttga aggaaatgtt ggagaattga ggaatgaaat
     8761 caagcttctt tgtgcagaag gttatttagg aaataagaga aagtcttcaa tttatttagg
     8821 ggacaaacta gacagcggtt tttggataga tccagaaatt agtatagatt taaaaaaaat
     8881 gtttcttaaa tcactttctg aaattgattt gattgaactt tttcaaaatc acatttcaat
     8941 tgaagaaagc atgagtcaat taagagatag aatacttaaa gagtgtgcag gttcttctga
     9001 gtataattat ttagaaagtg acgaatttat agcattaaga aactatgttg ttaataaaat
     9061 atcaccaatt attgattcga caggtctatg tttattagat gaattcttgg cggatatcag
     9121 tctatttata atgtttattg atgtaattga agaaacatca agaaattttt tgctgtctaa
     9181 gttcagaaaa tttcgtatga aaaatgataa acaaaaatta ttggcaaatg agatttggag
     9241 tagtttagaa gtcgaagaaa gtaaacaaga acttttgttg aaatggatac tttttcttgt
     9301 aaagaagttc tatgtgaaaa taccagaaac ccattgtctg atagttatgc acggtaaaat
     9361 aacagcttct gcgatcgcaa gggaaacaaa taagttgctg aatacatatg tttatgaggc
     9421 tttcgatatg ccaattgaag gtgagactag tgacttaatt aacctaatca acaatttttg
     9481 taaaagtata gatacgacga atggactcat tctgctagtt gatatgggat cattggaaca
     9541 aatgtatgaa aaaattgaat ccaatgtaat aggtgatttg gtaattttaa acaatgtttc
     9601 tacagcttta gcgattgaat gtgggattca agtttgccaa aaaaagccaa ttagtcattt
     9661 ttaccagatg gattttgatt cgtttcaagt taaagttcag tattataaag gattatcaca
     9721 aaagaaaaat gtaatagtat cttgtctctc tggtgagggg atttctgaaa aagttaagga
     9781 tattttaaaa cggtatctcg ataatcaagt ggagattttg atttttgatt ttaacgcatt
     9841 aaagaaaata gcaaaggaaa aagatactat gatttttaag aatacaattt gtgttctttc
     9901 aaccactgaa ttttacattc aaggaatcga ttgtttaaat ttagaaaatc taattaatgg
     9961 gaatcaaacc ttagaaaaat taaataagta tatggactcg gatagctgtg agttctgctt
    10021 aaatgaatta gttaaactct ttactattga aggcgctagt actaagcttc gctttttaga
    10081 ttccaaaaaa gtattcaatg agatagaaaa agtactatat ttgtatgaaa aatattacga
    10141 tgtcaaaatc ccaagttttc tgagaattaa tctatttcta catctttctg gaatgattga
    10201 acgaattatg attggtgatg gaataacaaa tgaacatttg aaagagggag cgcaactatt
    10261 tgatactttt ttaaatgtat caaaagattt tttttcagaa atcaaagata tttactgtat
    10321 tgaaataccc aaaggagagt atgagttaat ctatacaatt tttgagcaga ctattttcta
    10381 aatagcatac tagcgtctaa aaaaatgaaa gggtgtccaa agtatattta gacgctcatt
    10441 taattaatat ttactgtatt ttcccgcttt attggataat gttagttggc acagtaattg
    10501 cttatataaa agtataagaa gaaaggagag aacaaaatgg cgttttggca aacattttta
    10561 gttgtgttgt atggattttt cattaactgg gataaggaag ggcccaaaat cggaacctcc
    10621 caacctgtcg ttgcaggttt cttgaccgga cttattatgg gagatattca aactggactt
    10681 tatatcggtg ggactttgca attaatgaca ctaggtatta ctagttttgg tggtgcatca
    10741 gtaccggatt atcaaacagc agcattgatc ggtacttatt tagcaatctc aactaaccag
    10801 gatgcttcta taggaataac tttagcaata ccggtagcaa tgttaattgt acaactagat
    10861 gttctaaagt ggtcaacaaa catttttttt caacaaaagg cagaaaaatt cgcacaaaaa
    10921 gaagattatc aaaaattaga gtggatgcaa tatttggcat caattaatac aagctttgta
    10981 tctggaattc ctgttttgtt aactgtgata ttaggcccaa cgttagtggg aagtgcaatc
    11041 aattatattc ctgaatgggt taccggtggt ttaaaggtag cagggggact attacctgct
    11101 gttgggatag gaatgctact taaatattta cctacaaaag attactttgc ctatttgtta
    11161 gttggtttcg ttttggcagt ttatttccaa ataccaattt tagggatttc gttacttggc
    11221 gctgcaatcg cactaatcgt atataaaaat agatcaaata atactcaagt agcaccagct
    11281 gcaacaggag gttttgacga agatgaataa gaaactgaca aaaatcgaca aacaagtaat
    11341 tttccggtgg attctcaatg gtgcaacttc attaaattat gaaaaaatgg aagggttggg
    11401 ttatgcgtat tctatgcttc cttttatcaa ggacacatat aaagatgatc ctgaaggaat
    11461 gaaacaatcc gttttagctc acttacaatt ttttaacact acgccgtata cagcgcctta
    11521 cattattggt atgaatgttg gaattgaaaa agaagaaaaa aataagtctt tggaagcagt
    11581 aagtgctctg aaaacaggtc taatgggtcc tttagcggga attggagata gtgtatttgt
    11641 agttattcca tggactattt ttggagcaat tgcagctaat atggcattgg aaggtagttt
    11701 tgttggaatt attttgtgga tactggcatc aattttatta aggattactg cttatccttt
    11761 ataccttgct gggaaagaat cgggtgcgag cctactaact caaattgaaa caaaattaaa
    11821 gtctattact gatgcagtat caattttagg gttaatggtg gtcggtgcac tcattgccac
    11881 agttgtaaaa gtgaatgttg gctttgaatt taaacaaggc gacttaacaa tgaccggaaa
    11941 tgaaatcttt gatcaagtta tgcctggttt attacctgca tgtgtagtag caattgtgta
    12001 ttatttgtta ggacgaaagg ttaaaccagt ttatgtaatt ctattaatct tagtagtttc
    12061 tattgcgtta agagcgttaa atattttgaa gtaggtgttg aatatggatg aaaaaatgaa
    12121 aggtattata catgttcgta ttgatgatcg aatgattcat ggacaagtag caacacaatg
    12181 gacaaatcaa ttgagtgcta acagaattat ggttattaat aatgaagtag ccaatgatga
    12241 cgtaaaaaaa gctgtagttc gcctcgctgc accacctaat gttagaactt caataattac
    12301 aagggaagta gcagttaaaa atattctttc tggtaaatat gaaggacaaa aagttcttat
    12361 tgttgcagtt tctccaatcg atgttaaatt tttgattgat aacggtttac caataacaag
    12421 tgtaaacgta ggaaatttat caagaaggaa tggaacagaa cgcatccgtc cgacgataaa
    12481 tattactgaa gaagagagag aggcttttaa agaactaatt agtgatggag ttgaagtgac
    12541 agtgatacaa actcctagag attcaaaaga atttttaaag gattttattt attaagaaca
    12601 gaggatgagt ggatggagtt tataattaca tctcatggaa atattgccat tggatttgta
    12661 gatacattaa aaatgttttt tggcgataat ttaaattgtc atgtggtaac acttggagat
    12721 gcaggcattg aagaattccg tgaaaacatt gaaaaaatag tttctcaagt aaaaaatcaa
    12781 gaagttatgg tatttgctga cttgattggt ggaacacctt tcaacgaatt tgctaaaaga
    12841 agtgaagtat ttcaaaatgg gtttcaactt cttggtggca tgaatttagg aattttgatt
    12901 gaggctgtca atttgagatt acaaggaaaa aaaagcgatg atatcatcga aaatctaaga
    12961 aatatgaata caattgcgtg tcttgcagat atgcaaagac atactaacga agaggatgag
    13021 tgataaatgc aaaaaatttt ttacaagcct aaagattttt ggtttgggga ttgcatgcct
    13081 ttttataaag atggaacttt ttatctattt catcaacgag atacgagaaa tcctaaacct
    13141 ttaactgatc cttttgggtg gtcactagtt acaaccactg attttgtgaa atttgaagaa
    13201 tacggggaag taattcatcg tggtggcaac gatgacattg atcaatacat ttacgctgga
    13261 agtattgtcc aaggaatcaa tgagtattta gctttgtata ctggacataa tcgcaaagct
    13321 aagttggatg gaaaaacttc agaagtgtta atgattgcaa gttctaaaga tttaattcat
    13381 tggaaaaagg atggcgaagc agcaaaactt gttcctcaag aaggatatga taagaatgat
    13441 tggcgcgatc cttttgcaat ttttgatcaa gatcatggaa aatacgtttt gatactagga
    13501 gctagaaaac cagcaagtaa gaaaaagccg acggggagat tggtctattt tgaatccgaa
    13561 gatttaaaag attggaattt caaaggagac tactgggcta ataatgaatt taacatgatt
    13621 gaaatgcctg atatatttga aattgatgga acgtggtatt tacttttttc agagtattgt
    13681 gaagataaaa agactaaata tcgagtcgga gcaggattat tttcagattg gaaatcacca
    13741 gtagacgaag ctttcgacgg aaaagcctat tatgcagcaa gaacagtcgg aactaatgaa
    13801 actggccgtt ttctaactgg ctgggtggca acaaaagaag gggagaacga tcaaaataac
    13861 tgggattggg gcggtgcact tgttccacat caaattattc aaaagacaga caaaactctt
    13921 ggtgttaaac tgcctgaaaa aataattgag aattttaaag aaatcactcc attttcaagt
    13981 tttaagttag agaaagaatt tggaaaaaaa gaaagagtaa ttgttcctaa aatcgaagat
    14041 tattttctat ttgaaacaac tttgactatt acatcgttaa caaaggagtt tgctttaaaa
    14101 ttatttgtag atagtgatac tcaagaagga tacgaatttc gtatttcatt gattaataat
    14161 cagcttactt tcggaaaaac tccgaactat ccttggcctc aaatgtttga taaggggctg
    14221 caacgaccac tatttttgga aataggcaaa gaatatgaac taaagttaat tgttgatgat
    14281 acgatagctg ttttatatat tgataatgtt gctttaagta ctagaatgta tgataaagtc
    14341 ggaacagcat taagtatgac tgttacggag ggagcaatca aggtagataa actagactat
    14401 tcaataaatt atgaatgtgg attttaaaac aattgaaggg atgatgtaag tgaaattaaa
    14461 tggtttacaa catattggaa ttccaacaaa agattttgga gcttcaaaaa tcttttatga
    14521 atccttaggg tttagtctga ttaatgaaga aatgaatgtg ggaagtaaag tcggcttttt
    14581 cgagttgaat ggaacgataa tagaaatatg ggaagataaa actactgagt gtagaggagc
    14641 cattgatcat ctagcattag atacggatga catagatgag gtattcaatt caattcaaga
    14701 tttaggatat gaattattag ataaaaatat tatggaatta ccgttctggg aaaatggaat
    14761 ccgttacttt aatttctacg gaccaaatca tgagattata gagataagcc aaatgaagaa
    14821 ataaatagat aacgaagtgc tctaagttgg tatgaacgaa aagtacttca ttttttggta
    14881 tcagcatttc aatagtttaa tgagaattta ctatttcaaa ttaattcaaa gtgacagtat
    14941 tttttactta tttggtttca aattttgtaa tccttcctat ttattggaat acactccaca
    15001 ttttgtatac aagtcatatc atgttttagc aaagctctta ccaagcaaag ttataatgat
    15061 gttttccaaa gtttgatctt tcgatggagg ctaacacata ttttttgcag gacagccaaa
    15121 attagatgta tagaatagag tctgtgaggc gtatagacag tttattgtct gtatgccttt
    15181 ttttattttg aaaaattttt agtatttttc gaaaaatgct cactcctag
//
LOCUS       DADGKS010000064        15137 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.064, whole genome shotgun sequence.
ACCESSION   DADGKS010000064 DADGKS010000000
VERSION     DADGKS010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15137
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.064"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            4..2376
                     /locus_tag="JXV47_002191"
     CDS             4..2376
                     /locus_tag="JXV47_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488209.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEEYVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESAFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     RPTDSMKEKENDHFYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTLETPENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2437..3897
                     /locus_tag="JXV47_002192"
     CDS             2437..3897
                     /locus_tag="JXV47_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HAX1488210.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQIKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3908..6112
                     /gene="topB"
                     /locus_tag="JXV47_002193"
     CDS             3908..6112
                     /gene="topB"
                     /locus_tag="JXV47_002193"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAX1488211.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLRAEEISTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYES
                     LTPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGVLLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSIDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            6352..6945
                     /locus_tag="JXV47_002194"
     CDS             6352..6945
                     /locus_tag="JXV47_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection protein"
                     /protein_id="HAX1488212.1"
                     /translation="MQEKLKELLAIRDGNLSMKEARKLGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEIEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            6958..7857
                     /locus_tag="JXV47_002195"
     CDS             6958..7857
                     /locus_tag="JXV47_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HAX1488213.1"
                     /translation="MTPTQFAAKTRNLAKRTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTAQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIIGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            7860..8357
                     /gene="ssb"
                     /locus_tag="JXV47_002196"
     CDS             7860..8357
                     /gene="ssb"
                     /locus_tag="JXV47_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAX1488214.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMVTLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNALQNPFGNPFGGQSIDISD
                     DDLPF"
     gene            8723..8983
                     /locus_tag="JXV47_002197"
     CDS             8723..8983
                     /locus_tag="JXV47_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488215.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9428..9634
                     /locus_tag="JXV47_002198"
     CDS             9428..9634
                     /locus_tag="JXV47_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HAX1488216.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGQRAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            9682..9885
                     /locus_tag="JXV47_002199"
     CDS             9682..9885
                     /locus_tag="JXV47_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488217.1"
                     /translation="MVDKEVISEKVAEALLIPRYWTIETPLVEDAPTMLFEDLVKIAG
                     YELHYQENMETYENEYWLTKLEN"
     gene            9901..10338
                     /locus_tag="JXV47_002200"
     CDS             9901..10338
                     /locus_tag="JXV47_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488218.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            10331..11038
                     /locus_tag="JXV47_002201"
     CDS             10331..11038
                     /locus_tag="JXV47_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488219.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKHRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSCTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATIDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKRQ"
     gene            11418..11597
                     /locus_tag="JXV47_002202"
     CDS             11418..11597
                     /locus_tag="JXV47_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488220.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            11922..12185
                     /locus_tag="JXV47_002203"
     CDS             11922..12185
                     /locus_tag="JXV47_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HAX1488221.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            12179..12529
                     /locus_tag="JXV47_002204"
     CDS             12179..12529
                     /locus_tag="JXV47_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAX1488222.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(12553..13167)
                     /locus_tag="JXV47_002205"
     CDS             complement(12553..13167)
                     /locus_tag="JXV47_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAX1488223.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            13481..13903
                     /locus_tag="JXV47_002206"
     CDS             13481..13903
                     /locus_tag="JXV47_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488224.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            13913..14116
                     /locus_tag="JXV47_002207"
     CDS             13913..14116
                     /locus_tag="JXV47_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488225.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            14327..14911
                     /locus_tag="JXV47_002208"
     CDS             14327..14911
                     /locus_tag="JXV47_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAX1488226.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT         5570 a         2451 c         3060 g         4056 t
ORIGIN      
        1 aacatggcag aagaaaaaga accactagac aatagtcgtt tgggaaaatc caaaagaaaa
       61 ctagtacgat tgcaaaatga attaaacgaa caaattgaaa agatgtttga acaccaaaaa
      121 atgacgaacg gtcaaccaat gaacgacaag aggaatggcc gttcatggtt taaccagcaa
      181 gaacgaatcg aaaataaagt ccaaagtctg agagaagaga tcaagcaaca agaagaatac
      241 gtggaaaagc ttgaaagaca agaagagcta aaggaaatgg gctataacaa gtacggcgga
      301 ctggatatga cgatcgataa tattccaaga atcaaagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcgg ctttttcagc cgccacgatc cgaaaatacc aacggaagtt ggaaacatta
      421 gaacagctga aagaaaaatc agaaaaagga aaagaaaata tcctccctga agtacaagcg
      481 atcattgaca gcggacgagt gacgcaatgg aaaaaaaatc caaccattta ttttttgaaa
      541 ggctatcgaa aagttgcttt agaactgaat gaaaacgggg gatttgagga atcaaaaaaa
      601 taccaagcca cgtcggaaga ggaaaaagca gctgttcgtg aattacttga agaggctaga
      661 ccaactgatt ctatgaagga gaaagaaaac gatcatttct atcgagtaga attcaacgaa
      721 aatgatccag aaaaaggatt gaaaagttat ggtggggaga tcgtaacatt cgaattgatc
      781 gatcaactca aaacattgga taaccaatac gccgcagaag caggttatta taaattctat
      841 tttgaggaag tgaagaacgg agaagtagtc gatcagatcc gaatggatct aggggatggc
      901 gtcaacagta atcaaccaat ctatttagag ttagcaaaat tgtgcgaaca agtacctgag
      961 aaggaacaaa aacaatcggt caaaaatgaa cctgtttcga aagaacaaat gcagtcgaaa
     1021 gaaacaaaaa caaaacaaaa gggctatcaa aaacgaacgg cagaagagat taaacaagaa
     1081 gttaaatccc tttcgcaaca ggcactggat gcggtgaaaa agcataccca ttctcctgaa
     1141 gacgtcaaag aacttttgaa ctttatgtct cgttttccag aacgatcctt tagaaatcaa
     1201 ttattgattg aggaacaatt tccaggtgca acggcttgtt taggtcgtgc cgcgttgaaa
     1261 aaagaaggaa tctatatcaa aaaaggggaa caagggaaca agatctttgt cagaaaaacg
     1321 gtcaaagggt tttatgagaa aggacgtggc tttgttcgag aaacagaagc tacaccagaa
     1381 gataaaaaac gaatcgaaag tggtcaaatc gaagtgatca aaaaacctta ctatacgatt
     1441 gaaaaagtgt ttgatatcac acaaacacag ttaaaacctg aagactatcc gaaaatcttt
     1501 ccgaaccgtg tctttgattt tcaattggat aaaaaaggac agtcagaact tcaagctggg
     1561 attcaagcgg tagccaacaa tattggaata caaattcgag atatgacaga aagtgaagtc
     1621 tatcaaagag aattaggaca agcacgtggg gcgtatgttc gtaacgaatt tactggcgaa
     1681 gaagaaatcg tcatgaatac tcgaaatact cctacgcagc atttagctac aagtattcat
     1741 gaattagccc atgcaagaat gcacaaattt tcagaattag ataccgcaac taaagaattg
     1801 caggcagaaa tgacttctta tattgtgtgc aaacattttg gaatggacac gtcggagaaa
     1861 gctattcctt atattgcagc atggacgaag aatggtcaga cgttggatga taaggaagct
     1921 gcggaacgtg ggaaaatcat gaatgatgtc agccgtgtcg caaatgaatt cattcaaacc
     1981 atttctaatg aaatcaatca atacagagaa agagaaccag agatccaacc agcagaagtg
     2041 aagcaggagc ataaaaatac tttagaaacg ccagagaata agaatattgt gcccgttggt
     2101 tcactttgga tcgacaagaa agacgggaaa gtaatggaag aagatacggg tcgaacgtta
     2161 catttgaagg atgcggcgtt tattgaagat ccgcagcata atcaagtaat tttaaaagga
     2221 aaaagttatg gaaaagagat ccaaacggcg ttaccttcag aagaatttgc gctaggaaat
     2281 ccattccgat tttcacttga gacagtgtca gaagtggcaa aacgaaaaaa tgaaatctat
     2341 tatgaacaac aattgtcaca aaaagaacgt gtataaaaca agtaaaaaag actatctgaa
     2401 aaacggatag tcttttttct tttgggaggt tttaaaatga ccgagaaaaa aatgagtctt
     2461 attgatcgat gtaaacagat cgatatagtg gattttgctc gaaacaatgg aatggctgta
     2521 gtcaataaag gacgagatta tcgcttagaa gaccatgatt catttgtttt tgatcgaaga
     2581 aaacaacgtt tttattggaa cagtcaaaat attagtggcg acattattga attagctaaa
     2641 ctttttttca tagacaaaga gatccaagac cctaagcaac aatttaaagc agccactgat
     2701 tttattctaa agaatgaaga caaaacagaa cgagtggaaa atcttcattt tgaaacagaa
     2761 aagtacaaag atcaccccgt tgattatcaa ccactcacag aaaaaggaag gaattatctg
     2821 aaggaagaac gaaaactacc agagtggctg attgattatg cagaaaaaga agggttgatt
     2881 gccgaactaa agccaaaata tgaacggcaa aatttcttag ttcgagacga tcgtttagat
     2941 catgcggtcg cctttttatg gaaagatcca cagacaaaag agacagtagg ggcgagttat
     3001 caaggaacgt tcattgatta tgaacgtttt ggtgagagag gcacatataa gcatatagat
     3061 aaaaattcga cagcgaatca tggctttaac ctaaagatcg gtgaccctaa gcagataaaa
     3121 ttttttgaga gtagtattga tttacttagc tatgctgcac tgaatcgtga tcagttaaac
     3181 gatacgtggt tagtctctat ggaagggtta aaacaccatg tgatcagtca ttattttggt
     3241 gaggcagtat ctgaattgag aaagaaacaa gcctttcctc aatccatcga gatttgtgtg
     3301 gataatgacc gtgcaggaca tattttctac gaaaaagaac aattaatggg cgcagtcgat
     3361 ccatttacga atcagaaagt acgttgtgaa cgaggaatcg ctaatgattg gcaagtgcca
     3421 aaagaataca aaatcattta tgaagaagtc gcaaaagaag aaaaggtcac accagaagct
     3481 attatggcca tacacaagac agaaaacaat ctgcaattaa cgaaccaact ggtttccgct
     3541 cacaaagtaa atgcgttttt tggccagcag ctttctgtta acgattcaat agaagccatt
     3601 aatttgaaag atatttgtag agaagtcgca aaagaattaa aagtttgtga acgcgtggat
     3661 ggtacgtacg attttgatcg tttttatcaa gaaaaagggg atattaatgc gcagattctt
     3721 ttctcttata aagcagaaca atactacaaa ggctataaaa atcatgaaca tgaatttgta
     3781 cctgaagtaa aaaaggactg gaacgatcaa ttgaagcatg agatccagca acaagaaatc
     3841 agaaagcaaa aacgtgccat gttgtttcaa caaggcagac aacaagaaag ggagtgaaat
     3901 cgtcatgatg aaaaccgtta ttttagcaga aaagccgtca caagcgaaag cttatgccga
     3961 tagcttctct aaagccactc gaaaagacgg gtattttgaa atccaagatc gattgtttcc
     4021 tggtgaaact gtgatcacgt atggttttgg tcatttagtc gaattagatt cgcccgatat
     4081 gtacgatgaa aattggaaac aatggtcatt agaacatttg cctattttcc ctacacatta
     4141 tcactatcat gttcctaaag ataagaaaaa gcaattcaag gtggtgaaac agcaacttca
     4201 atcggccgac accattatta ttgcgacaga tagcgatcgt gaaggggaac tgatcgcttg
     4261 gacgatcatt caacaagtag gcgccgatca aggaaaaacc tttaaaagac tttggatcaa
     4321 ctccttagaa aaagaagcca tttatcaggg attccagcag ttacgagacg caaaagagac
     4381 ctatccaaaa tttgaagaag cacaagcacg tcagatcgcc gattggttaa ttgggatgaa
     4441 cggtagccca ctgtatagtt tactcttgca gcaaaaaggc ataccaggaa gcttttcctt
     4501 aggcagagtc caaaccccaa cgctttacat gatttatcaa ttgcaggaaa agattagaaa
     4561 tttcaagaaa gaaccttatt ttgaaggaaa atccgaagta atcgctcaaa atggcgcatt
     4621 tgatgcgaag cttgatccga atgaaaccca agcgacgcaa gaagcatttg aagattattt
     4681 aaaagaaaag ggggttcaat tgggaaaaca gccaggcatg attcgccaag ttgaaaccga
     4741 gaaaaaaagc gcggcaagtc cacgtctttt ttctctatcc agccttcagt ctaaaatgaa
     4801 tcagctcatg aaagctagtg ccaaagacac tttggaagcc atgcaaggct tgtatgaagg
     4861 gaaatatcta agctatccgc gaacggatac cccttacatt acggaagggg aatatgcgta
     4921 tctgttggat cacttagacg aatacaagca ttttttgagg gctgaagaaa tttcgactcc
     4981 tattcataca ccgaatagta ggtacgtgaa caacaagaaa gtccaggaac attacgcaat
     5041 cattcctaca aaaacagtta tgacagaagc gacgtatgaa agtctgacac ctttacaaca
     5101 agcgatttac gagcaagttt taaaaacgac agtggcgatg tttgcggaaa aatataccta
     5161 tgaagaaaca acgatcttga cgcaagtcca gcagcttcag ttaaaggcaa tcggaaaagt
     5221 accgatagat ctaggttgga agaagttatt tggcaaagag agcgacggaa aagagaagga
     5281 agaagagccg ctacttccta aagtgacaaa aggagaaatg gtgacggtag atctacaagt
     5341 ccttgaaaaa gaaaccaagc caccacaacc ttataccgaa ggtacgttga tcactgcgat
     5401 gaaaacagct gggaaaaccg tggatagtga agaagcgcaa tccatattga aagaagtgga
     5461 aggaatcggt acagaagcga cacgggcgaa tattattgaa accttgaaac aaaaggaata
     5521 tatcaaggta gagaaaaata agcttgtggt gacgaataaa ggggttttgc tttgccaagc
     5581 tgtggaaaaa gagccgctgc ttacgagtgc cgaaatgacc gccaaatggg aaagctactt
     5641 gttaaagatt ggagaacgaa aaggaacaca aaccactttt ctagccaata tccaaaagtt
     5701 tgtctctcac ttattggaag tcgtcccagg acaaatccaa tccattgatt ttggatcgac
     5761 gttacaagaa gtgaaagcag ccagtgaaaa gcaagaagcc gcgcgtcatt taggaatttg
     5821 tccaaaatgc caggaacaag aagtcttact ctatcaaaag gtggcagctt gtacgtctga
     5881 agcctgtgat tttaaattat ggacaacgat tgccaaaaag aaactcacag cgacacagct
     5941 gaaggagatt attcaaaata gccgaacaag ccaaccagtg aaagggttaa aaggtcagaa
     6001 gggttcgttt gaagcaacga ttgttttaaa agaagacttc actacaggct ttgaattttc
     6061 tgaaaagaaa aaaacgaact tcaagaaaag aacacgacgc acgacaaaat aatggagggt
     6121 taatcttatg cgtaatacaa cacacaaaca acaagaaatc gaaaatcaaa aagccaaaat
     6181 tcgttcagaa caagagaaat tacgtgccag taaaagaaga cttcagcaat taaagaacca
     6241 gcaacggatt caaaaagaaa tcgaattaga tcgatagaca ttaaccttgt tacaaataca
     6301 ctatcatgat atatttaatg tagtgtattt gtaacaaaag gggggaagta aatgcaagag
     6361 aaactgaaag aattgttggc tattcgcgat ggaaatttat ctatgaagga agccagaaaa
     6421 ttaggaatcg cagcaaccac tgtacaaaga ttggtgaatc aaggaaaatt gatcaaagtt
     6481 gatcgtggtt attatgtaga ggatggtcat ggaatagatg atttattttg gcttcagcaa
     6541 cgtttttcca ggggaatctt ctctcatgaa acgactttag atatttacca gctttctacg
     6601 aatatgccga aattcattca cttaactttt ccccatggat ataacgttga tcgttcaatt
     6661 acaaaagagc agcagttaca atttcatttc gtgaagaaag aagtttatga actaggaaaa
     6721 gtagagggaa cttcctttca aggaaatcct attactatgt atgataaaga gcgtacactt
     6781 tgtgatattt ggaatccgag atatgaaatt gaatatgaaa tgaaattaga agcattaaaa
     6841 gagtacatgg aagacccatt gagagatcca agtaaattaa gagattacat gacaaaacta
     6901 catgtagaaa aagaaatgaa ataccacatg caaagcttat attgatggag gaaaaagatg
     6961 acaccgacac aatttgcagc aaaaacaaga aatttagcaa agaggacagg attaaatgca
     7021 cagttagtac aacggcattt tatgatggat cgtttaattg aacaaatttc tgaatctaag
     7081 tataaaaatg atttcatttt gaaaggtggc tttttattag gatcaaaata tggaatcgat
     7141 agaaggacga caattgatat cgacacgaca tttagaaata gcaaattaac tgaagaaaaa
     7201 ttgaagagta tttttaatga tttaactagg aaacccacga aagaaggtat tgttttctct
     7261 attcaaggaa tgaaggaaac aagagaagcc gatttttatc ctggatttca aattaaattg
     7321 gtggctaatt tagagaaagt acgtgtgcca tttaaaatgg acgtgacaac aggagattct
     7381 atttatcctg aagtagatac acactatcac caattaatgt ttgaagataa aaaggtggag
     7441 attccagctt atccaacagc acaaattatt gcagaaaagc taagtgctac gttcagcttt
     7501 ggcacagata attcgagagc aaaagattac tacgacttat ttaccattcc gaaactagaa
     7561 aatatcgata cgaaagagtt atacaaaagt gttcgaaata catttacaaa acgtggggat
     7621 acaaaaccgt tgtcctttta ttatgaaaga gaaatggata agatcatagg aaatgactat
     7681 ttggaaaagc agtgggaaaa atatcgctca gttaacacgt ttgcgaattc catttcattt
     7741 acagatacag tcaacgaaat tgatcaccta atgaaaagtg tgatcaaaat tgaaaatcaa
     7801 gaaagaaaac ggcagtttaa aagatcacaa caaatgaatc aagaaatgga gagataaaga
     7861 tgatcaataa tgtaacttta gtaggacgct taaccaaaga tccagattta cgttataccg
     7921 cgagtggtac tgcagtagcg acttttaccc tagctgtcaa ccgaaatttc acgaatcaaa
     7981 acggcaatcg agaagctgat tttattaact gtgtgatttg gcgcaaacca gcagaaacaa
     8041 tggtgacatt agctaaaaaa ggtagcttga ttggtgtagt tgggcggatt caaacgcgga
     8101 cttatgacaa ccagcaagga caacgtgtgt atgtgacaga agttgtggcc gataatttcc
     8161 aactattaga aagcaaagca gcgacagaaa gccgtgcgca cgctgatcaa tcgtccacca
     8221 gtccaagcac caccactttt gaacaacggg atacagcgac gcctaataac aatggattga
     8281 acgctttaca gaatccattt gggaatccat ttggtggaca atcaatcgat attagcgatg
     8341 atgatctacc gttctaagta gcattttcta ttggttgcat ttgctacggt ttatgttata
     8401 atttagtcaa caaaaagaat tttcaatcta taaccaaaaa ccactagctg gcgggctagt
     8461 ggttttcttt tacgtttcta ttataagaat taacgggtag gcttactgtc tttcttggca
     8521 aatttacaat caagccattt gcagatatag tgcgcggcta cttctgccat gattgcaaaa
     8581 acaaaatcaa aaagaatttt caaacctata acctcctccc cttgccagat taggccgggg
     8641 tagcagacag caagactatt atagcataat tgaaatatcc aaatgattgg atttttgcta
     8701 taattttagc gaggtgattg tgatgaacaa atatgttggt ttgcttgata aaatccgagt
     8761 aataaaaacg caaccgttat tggttcgctt tactttacaa acgattcatg aatcgattaa
     8821 ttgtgtagtt gcagatattg aaattatcga taaattgcta attatggatg atggaaaata
     8881 caatattgcc gtcacaggtc acttcaataa acgaaatcag ctagttattg ctagcatgta
     8941 tgttagaaat cccgatcatt ttacgcgatc gatgggcata taaaaaaaga agagttgcaa
     9001 tcctaatgta ggactgcagc tctttttgtt ttacatagaa acaagaaaaa tgaaaaggcc
     9061 tttttaggaa ggcgcgagcg ccttctcaat tgaaaaacct ctctcactcc aaccgccacc
     9121 gccgttcgag aagaaaggaa gtgaacgttg cacgttcact aagataaagg gtcttgcaaa
     9181 gcaagacaaa atagaaaaaa cttcctctca ccaaaaggtt cgttcctgtt cgttatctct
     9241 ttattgattt gccagaccgg caacaagttg ccttttatca ccaaaaagcg acaaggacaa
     9301 gggtaaatgg cacgctgcgc gcccttgtcc ttgtcgcttt tcgttgattc attctggcca
     9361 acaaatcaat aaagaaagaa ctaacgaaag gaagtaaaac ctttcctaag aggaggcaga
     9421 atcaatcatg cgaaagaaat ttgattattg gggtgttccc ttcagcgaat tattcccaaa
     9481 ctatcatgca ccacatactg tcgaatgcga ttgtggacaa agagcgaaat gtatcaaaag
     9541 ctatcgtttg tatcaatgtc caacatgcgg aaaaaaatac accttgtctt atggcgatta
     9601 tattttgatt gatgagaaag gaaagaaacg ctgatgaaaa cataacataa attattgact
     9661 gtaaaagaag tcgttcaaat tttggtggac aaagaagtca tttctgaaaa agtagcagaa
     9721 gctttactta ttccgcggta ctggacgata gaaacccctt tagtagagga tgcaccgact
     9781 atgctatttg aagacctagt gaagattgca ggatatgaac tgcattatca agaaaacatg
     9841 gaaacttatg aaaacgaata ttggttaacc aaattagaga actaaaaagg agaaaaaaat
     9901 atggctcaaa attactatga cgaatttgtc aaattacctt tggataaaat ggcacaaaaa
     9961 atggaggata tgacattcct ataccatgag acacgtgttc caaaaaaaca ttataaggaa
    10021 agattgtcgg tagctgtgga agaaatgatt gaatcaggtg tcgaaatgaa tctcattgcg
    10081 acgtactatc gaacactgga agaactgaaa aaacaaaatg caaaatggtt tttccaagcc
    10141 ttactatgct tggaagtagg tgtcaaacca agcactatta aaccttctga atatcaagct
    10201 ttagaactaa cgtatgggaa atttgtcgaa acgaaaaaag ccaagactgt ttcaagtgaa
    10261 tggttagatt attttgaaaa tatcaataag tatggcgcct attacaccat gaaaaaggag
    10321 gacaacgaaa atgaataagg tgatttatca actaacaacg gaagatgtgt cacacttttt
    10381 aacaaacaaa gaacatttga atgaagtaat cagacggatt caaaaagact ttagttgtat
    10441 ggaagaaatg aagtacttta ttcaaagagt cgaagaacaa ttgtatttgg aaagtgaaac
    10501 gagtcaaacg aaggtcacag tcagcaataa ttatttagac gtgtataaac atcgtcctga
    10561 aacggtaaaa aaaggaacgg agcttctacg actagaaaca gaaaaataca tcatgaatgt
    10621 ttacctagaa aggagtgaac tggtcgaaaa ctttgtcagc tgcacgattt gcaggaaaca
    10681 ctattactca gaatcagaat attattcaat ttttgagagc atggaattaa tggaagaaga
    10741 aatggaagag ctaaacagca aaaatgcgac gatagacgat tattatcttg tatttactag
    10801 atttttgacg tgtggaacgg aatctatcgt gttaatggga atggattatg aactcgctgt
    10861 acccgaagca tttttgaggg aatatgtaga agaagtagat aacccaggcg acgactggta
    10921 cacgacttta actgattttt tagataccta cacttacgac gatacagaag aaatccaaaa
    10981 tgaacttgac cgtaaacgaa tgccatatca acgatttgaa aggaaaaaaa ggcaataatc
    11041 atttataccg aaaagtgaga atgtgtgaaa taagaacaaa aaccttgaaa ttaagggaat
    11101 ggttcttatt tcgcaccaat cgctccaacc gcccccgccg cttaggtggt gcgaaataag
    11161 cgggcaaagc ccgataacct aagagaaaga aggagatcca tatgaataaa atcattcctc
    11221 tgttgttcgt actgtgtatt ggcgagatac ttatgcgtca tggtgcagct gtacatttaa
    11281 acttcgtagt attcttagga atactagtat tttgtttgat tttttggcgc tttgtgttag
    11341 cccttgtgag tctactattc aagttgattg cagccatatt tttcataggg ttatttcgat
    11401 gaaaggagag agtactaatg ccaattgcaa taggaaataa acggttaccc gtgacattag
    11461 atgaaaagag acaaaaagaa ttgcagcaac taaagcagaa gtacggaaaa agtgaatcta
    11521 agattatgtg tattgcgtta gatctattga tcgcgcaaga aaaagcagga tttgatatac
    11581 cagcactaaa aaagtgacgt cacttttcat ttgaagaaac aaaagtgata gcacttaatt
    11641 gttcctacta tttagaatat tttctatgtc ctttttattc cattttgtat caataactat
    11701 gaaatcttta aagtatccag atcaattttt ttcttacctg attctaaaga ttttgttttc
    11761 ttaaacatat tatgatttcc tttcgactat tttcatataa atgttaacat agtttatgga
    11821 ttcatggaat gttaatctaa tttaatagaa aaggataatt aagtatatac gttttttctt
    11881 atgtatgtta tactatgtat atacagaaag aggtgtctac tatggaaatg ttacctataa
    11941 aaaaatgggg aaatagtaat ggccttagat tgccaaagta tattatggaa tatcttggaa
    12001 ttcatacaga agacaaagtg aagataatac aagaagaagt aaacggtcag aagcggctaa
    12061 ttatcgaagc ggctaatata gaaaatgaat taacaattga acagttattt gaaaattaca
    12121 ctgatgaaag aaatcatgtg acgattcaaa atttaggtga agcagtaggt aatgaaaaat
    12181 ggtgagaaaa cctagacaag gcgatattct attattgaat acagcacctc gatctggaca
    12241 cgaacagaca ggtaaaagac cttatattgt tttaagtcat gatattattg cggattatag
    12301 taacgttgtt acagttgctc caatttctag tacaactaga aactatccgc tatatgtaaa
    12361 tataaactca gaatatgaaa tgaagacaac aggaaaagta ttattagatc aactaacgac
    12421 aattgattat gaagccagag agtgtatttt tttggaaaaa gcgcatgata gtttagttga
    12481 ggagttattg atgaaagtta gaacagtttt tcaaaaagta agcaaataaa atagaaacag
    12541 cagcatgatc aactattcgt gattgaccat gctgtctttt tttattctat atacggtttg
    12601 tctcgtaaca ttgtagtctt ttgcaatctt agcgatcgca acaccttttt ttagatcctc
    12661 aacgatgttt ttataaacaa gacgacgttg gggatctttt gcattggcac tgtatagctt
    12721 aggacgtcct ttataaacac cgttcgcttt tgcaatctta atgccttgtg cctgacgtcg
    12781 tttagattcg gtacgttctt gttcagcgat catggccaaa atttgaatga tcaaatcttt
    12841 aatgaattta tccaggagag gattgccaat tgcttcggcc atgatcggta gacttgtgat
    12901 gatcagctgc acatttttct tcttcaagta attgactgaa gcgatgatct cgtcgtaatt
    12961 tcttccaagt cgatcaatag cttccacaat aaaaatatct tgatctcgga cgaaatccag
    13021 tgcttcttga aaaacaggtc gatgagtaat cgttgcgcca gattgtttct caatgaaaat
    13081 tctctctgca ccgaattttt tcatttcttc aatctgccgt tgttcatttt gatcgatgga
    13141 tgagacacgt atgtatgcaa ctctcaaaat ttttacctac tttctgcaac tatttaaaaa
    13201 acaccctaat catacacgag aaaaccagat ttttcaatgt cgcggtcgtg tctagttagg
    13261 gtatacctta tatagacaaa aactaatgat ggaggaaata gtatgtgtca cttttctttt
    13321 taaatggcaa tattttttgt aaataaatgt caatcaagaa aatttaaacg attatgacat
    13381 taaaaatata ttttatgaat tttctagtat ataacttgat ttatctgtta agatttatta
    13441 agaaaacgtt ttcttatttt tgatttcgag gtgatagaca atgaaaaata agtttatttt
    13501 atctttaggt attttaacta ttggaattag tgtaactgga actacaattc ctacatttgc
    13561 tgatagtaca aatgaaccaa ctactgtagt agataataac caagaattaa ctcctttaga
    13621 taggaacgga atagccattg gtaacccaac taacgactta actgttactg aaaattattt
    13681 aatagtttct ccattacttg ctcgagcagc ttctaaaacg atacgagtga caggaacgat
    13741 gatttttgat aaagttggtt ggccttctag acctcctcaa tcacggaatt ggaaagaaaa
    13801 aagaaatggt tattggtact atggaaaatt gtatttacaa agttataaat cagctggaaa
    13861 caattggatt gcgacttatt caggaacctt aactagaaag tagggatttt ttatgccaga
    13921 atttgtgaac acaccaaatt tttatcaaga tagcgatatt ctaagtaaaa ttaatttacc
    13981 gaaagaagaa tcagctttac aagttcagcg aactttacag gagacacaaa aaattcaaaa
    14041 atcaatttct aatctagaag attctgaaga aaaaagaaaa aaaagagacc aaaaaacata
    14101 tcaaaaagaa aaataatgat tttaaaaaaa gagtgtctag tcgacattct ttttttctaa
    14161 ttgaaagtgt tcataaaatc acccatttct ggacactttc tttttttgct ttatttttca
    14221 aaaaaacaat tcatttcatg ttcataaacc cataacaata tctatgttca gttaaactat
    14281 atggataaag ttatgttaca ataaaattaa tgaaggagtg atttttttga aaataggata
    14341 cgcccgggta tctactggtt tacaaaattt ggatttacaa gaagacagcc taaataaatt
    14401 tggttgtgaa aaaattttta ctgatcatat gagtggggca aaaagtaatc gaccaggatt
    14461 agaaatggcc attgattttg ttcgctctgg cgatacactt gtcgtttggc gcttagatcg
    14521 tttaggtaga aatatggaag atttgatttc aatcgtcaat cgactgaatg agcgtggtgt
    14581 gagttttcat agtattcaag aaaatattac gatggacaaa tcaagttcta caggacagct
    14641 catgtttcat ttgtttgcgg catttgcaga atttgagcgt aatttgatcc tggaacgatc
    14701 cgcagcagga cgagcagctg ctcgtgcaag aggacggttt ggtggtcgtc ctgaaaaatt
    14761 gtctgaacaa gatttggaat tactgaagac tttagtggat agcggtacac ctattaagac
    14821 tattgcggaa cggtggaacg tctcaagaac caccatttat cgttatttgg caaaaatgga
    14881 ggagaaaaat ggaaagacaa attctcatta gtttttgtca tttaatgctg aaaatttttg
    14941 ccatttatct agaaaagtga caatagtatg agaatttttt gtaagtgtct actgataact
    15001 tattctcaaa tgttgtaagg attttattca tttgttaata ttaaagaacg gaactccaaa
    15061 aaagtccgta ctctaatttg cagtctctca ctcttttaga gtgagagttt ttattagatt
    15121 ttcaaattaa ttagtaa
//
LOCUS       DADGKS010000065        15093 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.065, whole genome shotgun sequence.
ACCESSION   DADGKS010000065 DADGKS010000000
VERSION     DADGKS010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15093
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.065"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..444)
                     /locus_tag="JXV47_002209"
     CDS             complement(<1..444)
                     /locus_tag="JXV47_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488227.1"
                     /translation="MIIKKKFTVLLTIIVTGIMSGFALVIINKQVLYRTNEFFHQTDT
                     YTPIRLPQHFIGQEEYEQLIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLE
                     MTLYYQGDVKSSHEKVPYSNTSFRVTSIEESIKIKDFEGEFFLMTR"
     gene            570..1235
                     /locus_tag="JXV47_002210"
     CDS             570..1235
                     /locus_tag="JXV47_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1488228.1"
                     /translation="MNIGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHQTLGLPIDFPSIESATESIEPTLPDEPLVIKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETVDRFNPFLKPQIGYTTLPVGYVENSIEHWVCNDIFVHGTW
                     LSFHAGEVEKGKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILIQDYDDALKRSPQEP
                     DRH"
     gene            complement(1632..3665)
                     /gene="brxL"
                     /locus_tag="JXV47_002211"
     CDS             complement(1632..3665)
                     /gene="brxL"
                     /locus_tag="JXV47_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002397592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease Lon-related BREX system protein BrxL"
                     /protein_id="HAX1488229.1"
                     /translation="MEQQEILKLSEFFPGKIVRKDLTKKIKEGANVPVYVLEYLLGMY
                     ASSLDETLVEKGVENVKNILARNYVRPDEAEKVKAKIRELGGYTVIDKVTVHLNEKKD
                     CYEAEFSNLGLKNVQISEEYPKKFDRLLGGGIWCIVSMEYWYDENDRWNSPFIAKKVD
                     PIQMPGLDIEAYKMARKEFTTNEWIDLLLRSIGMEPTQFNKRVKWLHLARLIPLIENN
                     FNLCELGPRGTGKSHVYKEISPNSILVSGGQTTVANLFYNMASRTMGLVGMWDCVAFD
                     EVAGIKFKDNDGVQIMKDYMASGSFARGKEEKNASASMAFVGNINQSVDVILKTSNLF
                     EPFPEVMGTDSAFLDRMHCYLPGWEIPKYRPDFFTNDYGFITDYFSEVMRELRKVSFG
                     DSFDKYFKLGSQLNQRDTIAVRRIVSGMMKLLYPDGRFEKSDVEEILRFALEMRRRVK
                     EQLKKIGGMEFYDVNFSYIDLEEEREEYVSVPEQGGGTLIPEGLGKPGHLYTVSYGKT
                     GQLGTYKLETQMTSGNGKFERTGINSDAGAREAMDSAYRYLRANYGSVSQSISLTTKD
                     FVVHVQDMNGIGMTKTLSLSTIIALCSVSLNKPVLPSLVILGDITIGGSMIKVDNLAN
                     CLQVAKDAGAKKVLVPMISAADIGTVPPELMGTFNLIFYQTPEDAVFKALGVE"
     gene            complement(3783..6305)
                     /gene="pglZ"
                     /locus_tag="JXV47_002212"
     CDS             complement(3783..6305)
                     /gene="pglZ"
                     /locus_tag="JXV47_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system phosphatase PglZ type A"
                     /protein_id="HAX1488230.1"
                     /translation="MTDINTQQIEEKLNQRFPNYGCRKIIFWFDSNQDFLEEIDSLVI
                     QNAKIYRLEKDAQFKTKRLLEYEDPETNYLIYAPFPRWDDKDEDNHLLSVLNYSEEFS
                     ADRLAIIMNELAIPLRFHQTVKQYRNFFNAKDRMRSFGEFSTHMTINKSETIELMIMA
                     VLLKSKSIRLNDLLRVVLKSFTESRENPLRELDKYQLTAKFWEFIQMKFGFTDSQPTL
                     EKLTMCLYLNYFYYQIDQEMPKKFKGFEILHLKANIITFMDQFMNDTRYMESFEQLSK
                     KVYQAIDGDGLLDSIEIDDLIEADVFSEIHAKILMFYAERLKASDTTTKIAGQTIFDS
                     LKQREKMHFASDYIYEYQLLKHAYYLVDKNRLCLPMNMDNLLTQYEKEMYWVDTHYRK
                     FIWNSDHIEEKQKYGQLYRLVEANYSKFLDQSGQIWNQTFEFKNRPSIRKFYNQAVMK
                     RSVKTVVIISDAFRYELGMNLERKLVREKKYSTNMASFLSVLPSVTEFGKAALLPNNQ
                     LTYNEGTEVLIDGKKTNGLSNRNAILQQRDANAVALNYDDVVKMNKAEVREVFNGKSV
                     IYIYHDQVDRTGDHSNENRVFEACDLAISEISRLINRLHNDGSIYRFIVTADHGFIYK
                     RSHVEEVDKIENPSRNEKDRVERRFILSEEEYEIIGTKNYSLGDSLGNDDTRNICVPI
                     TSSIFKKAGGGQSYVHGGSSIQEMLVPVLEITVAKGSNAKEPVAIELMTSNRRITGLS
                     TTLEFYQKNAISDVYDPASFWLYFEDEYGERISNEEIYVADSKTEDANQRFTKFVFEF
                     VNRRYTVEDTYYLVIKNQKNDLTERIKFIIDNPFAESFDFDI"
     gene            complement(6421..10053)
                     /gene="pglX"
                     /locus_tag="JXV47_002213"
     CDS             complement(6421..10053)
                     /gene="pglX"
                     /locus_tag="JXV47_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system adenine-specific
                     DNA-methyltransferase PglX"
                     /protein_id="HAX1488231.1"
                     /translation="MDKKAIKNFAVNARRKLIDEVMTKAKRLGIDESKIEDVKKIDSN
                     LQEIEKSGIRIQGKEIAQRNKLIAELKQRASVTSYSEAFQELIEEVAYTWFNRLIAIR
                     FMEVNDYLPDTYRVLSSEISGKIEPDIITDIYDADIFEELSSNEQQQVRTWKTDNSAE
                     AMDKLYQLIFIKICNQLNDYLPELFEEVEDYTELLFTASYIKKDGVIADLLSIPEDDF
                     YVQAGGQVEIIGWLYQYYNSEPHNQVVNIYKGIVKKQDIPAATQLFTTDWVVRYMVDN
                     SLGKYWLDHYPNSELRNKLKYLIPDKYAFEQATSVSNLKPEELKIIDNAMGSGHILVY
                     AFDVLMEIYLTLGYSERDAARAIVEYNLYGLEIDKRAYQLSYFAIMMKGRQYDRLFLK
                     KSLSPNLREFIDSPKVTDEYQERISELNNDKYSERWNEYKELIFDQFENGKELGSIIK
                     LVDKNNQAITKEYLGKVREYISKFNEFTNMDILYGMKEIQEKYLHILDVAEMLVDKYV
                     AVVTNPPYLNKMDKKLKKYVNDNYSDVKKDLFSVFIKLNSQMLIDNGYASFMTPFVWM
                     FISSYEKLRSFLINERNISSLIQMEYSAFEEATVPICTFTIKNSNEQDGSYIKLSDFK
                     GGMEVQKIKTLEAIHQHGECDYFYSTNQDNFKKIPGMPIAYWASDNVITDFAQGKLTN
                     DVADAKQGLATGNNNKFLRYWFEVEFNKIKFDAKTLEDAKKSRKKWFPTTKGGRFRKW
                     YGNNEYVVNWENDGDEIKNYVNENGKLKSRPQNLNYYFKKGITWSTLSSGQVSFRLQN
                     QAIFETKGSVLFSKDITDFEEIFGYVNSKLVNHFLTFISPTLDYHEGPMGKLPFLKVT
                     SERKLKKIREKVDENIDIARKDYNALETSYEFRRNILLSYMFKKDLSEAFNCLSRQLV
                     NQFNTLKSNEEELNDIFINHYSLEKELTKEVQDEYISARLPDKAREIKDFISYSIGCI
                     FGRYSLDEDGLIFAGGEWDPSRYQKFKPDTDNVLLITDDEYFKDSQIDIVNRFIDFVE
                     ITFGKETLEENLQFIADTLGGKGTSREIIRRYFVQDFYKDHLKTYSNRPIYWQLDSGK
                     QNGFKALMYLHRYTPDQLGKVRTEYLHELQKAYDNRIELRQQQISTSDNPKERNAMTK
                     EIVKIQKQLKEVREYDEKLGHLALKRIELDLDDGVIVNYDKLQRDPKTGEKFQIFAKG
                     VKEPKK"
     gene            complement(10117..13788)
                     /gene="brxC"
                     /locus_tag="JXV47_002214"
     CDS             complement(10117..13788)
                     /gene="brxC"
                     /locus_tag="JXV47_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX system P-loop protein BrxC"
                     /protein_id="HAX1488232.1"
                     /translation="MLIKDIFAKPIDRNIQGVIKVGQAKDENVQQELEEYVVTKELQK
                     HFKTIFDAYQRSINTPTDKMGVWIQGFFGSGKSHFLKIISYLLANREINDKKAIDYFK
                     EDGKIKDPLTLATMERCSQINTDVILFNIDSKSDAGGKKDKNGIVNVFLKVFNEMQGL
                     STIPHLADFERRLIKEEKFDAFKAAFEEINGAKWQEERHEFDWIQDDIKEAALKIDFM
                     SEAAIDNFLEKASGNYLISIDDFANLVKSYLDSKEADHHIAFLVDEVGQYIGGNRELT
                     LQLQTVVEDLGRICEGKAWVLVTSQEAIDHVTNFDNNSDNDFSKIKDRFATTVSLSSA
                     NADEVIKERILKKKEFANDSLALQFETVQTELKNKLLFVDSPELKLFQDAENYAEVYP
                     FIPYQFNLLGQILTEIRNHSYQGSNLSSGERSLLAMFKEAAERNKENDTTSLVSLDQF
                     YYSLERWIDTAISRVITQATNNSHIQRPTDIDNFNVNVLRILFMIKYVDQAIKPNVEN
                     ITSLMIRNINEDRLETKKRVEEALDLLIKENFVRKNLDSYIFQTDEEQEITREIKNQN
                     ITDSDLIVELSKRIFDGVLDRNSFAYEKLGMSGGNKFKNRYTFTYAQVLDQRPYKQAG
                     NAEMTVNFISPYSDLAGQEAELALKSSRNLLFVELPSDKEFKDDIAMYARMNLYLTTT
                     YSSVVKNFDAIRSEKSGELQELSASINDQLNELLKSAKFFYNGAEIQLTGSDFKAKFQ
                     SALQKMAEEVYHKLNQIDAPKEKEDILYLVKESKNEIIEDPSNEQAVQEIFNFINDQK
                     RNHLTITMKTIRDRFETKQPYGFTELDVEWCIAKLFMSGKIDLLYNNVQISRMDDPNS
                     IVMIIQKRRESEKIKIEPSAVISPKAKKLVDEIGRELFQSRNIVDENNNEHTMENFKK
                     YLKGQLDNLRSYFDLQNTYTYPSAYEYEQIKKYLEVIVQTSDVEDFFYTIKKYRDELF
                     DWAETYDKIKNFHKQNSTQKKIWENAQDKIRLIEKSRRQTSSQEIDQLIHEMKTILKK
                     ADPYSDMMKLNELIQEFIEQYNQLLELESQEILNKLTEEKQATFKLLEGKDFKDQFVP
                     IVDQEFQELKAKIEQANTIDDLVFLSLNVAEQYLIFNQRFDNEENRRRQEEQARKQIE
                     AANLIRETEKDEIDSAAKAEEIAIVKPTIQQKTVPMRTLNVHVKTIKSAADIDELTAE
                     INQKLKEQLQENTEITIQF"
     gene            complement(13813..14388)
                     /locus_tag="JXV47_002215"
     CDS             complement(13813..14388)
                     /locus_tag="JXV47_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1788 domain-containing protein"
                     /protein_id="HAX1488233.1"
                     /translation="MSLSIQEHLEKLNEVIQKEDFLLNRGLGNEVGYYIFDYDPKDEL
                     IVRDYINDISGTSVGDNYEVKVYNLYVIMLEYLEKRGFTEKAIKMEERRGLQKLVESI
                     GRLLKMDLPEEENVFFEYVDAHTPEKSVVFLTGIGELYPLIRAHSILNKMHQVFDRVP
                     VVMMYPGEYDELSLTILNTNKDDNYYRAFRI"
     gene            complement(14388..14987)
                     /locus_tag="JXV47_002216"
     CDS             complement(14388..14987)
                     /locus_tag="JXV47_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1819 family protein"
                     /protein_id="HAX1488234.1"
                     /translation="MNKKYSAGLVSKRFWFSEFKLYIQLRLEGYTDIEIKEKNEHENI
                     FFAVSSNRQKEIYQNVKRRVSQLDEAGLQLFNQLNIDNQKLVNLISILMIDDLFNEFM
                     TEVYAENLRKGNLQLTPVDYRSFFTEKRRSSEDISKWKDYTIKRLIAAYQTNLIETGL
                     VRGEKEYGRMTPILLDKRLIQWLVDKNRKDIVLALGGIL"
BASE COUNT         4646 a         2905 c         2079 g         5463 t
ORIGIN      
        1 tctcgtcatc aagaaaaatt caccttcaaa atcttttatt ttgatcgatt cttcaatgga
       61 cgttacgcga aaggaggtat tagaataggg taccttctcg tgagaagatt tgacatcccc
      121 ttgataatac aatgtcattt caagctttgg ctgtatcttg aagttccaag atgtatctac
      181 ttcattggat tcatttactg tttttttcat ataagaaagc tcagtttctg atgagacatt
      241 ttcaaatacc atgattagct gctcatattc ttcttgccca ataaaatgtt gtggcaatcg
      301 aatcggagta taagtatctg tttgatggaa aaattcattt gtccgataga gtacctgttt
      361 atttataata accaaggcaa aaccactcat gataccggtc actatgattg tgagtaaaac
      421 tgtgaacttt tttttgatta tcaccactct cccttactta aatgattctt tgataaaatc
      481 ataccgtttt tcatcaaaaa aacgtatcta tcaaatgtat aggtcatgta gaataaatct
      541 atatactgta gaatcgaaag gagaagaaga tgaacatcgg agaaaaaata cgaacttacc
      601 gcagaaattg taagcttacg caaaaagaat taggcgaaaa aatcggtgtt tccgataaaa
      661 caatctctag ttgggaaaat tctcgtacaa tgccagacct tgaaatgctg tcacttttac
      721 atcagacttt aggtctgccg attgattttc cttctattga atcagctacc gaatcaatag
      781 aaccaacatt gccggatgaa cctcttgtta tcaagaaatc ttattcatca aaacaaccct
      841 tctcactcaa aaagacacta tctttctttc tgctcgtctt ttgtttggtc tatctttttc
      901 ttatcaatta tcaatataaa aatgaaacgg ttgatcgatt caatcctttt ttgaaaccac
      961 aaatcggcta taccacactc cctgtaggat acgtggaaaa ttccatcgaa cattgggtat
     1021 gtaatgatat ctttgttcat ggtacatggc tgtcttttca cgctggagag gtagaaaaag
     1081 gtaagaatca tgctgtaatc aaacacaaag gaaaacacgt catgaacgtt cgcctgctca
     1141 cttgggaagc cattccctca gattaccaag aaatcctcat ccaagactat gacgatgcct
     1201 taaaaagaag ccctcaggag ccagataggc attaagtagg agatgaacgt agagatagaa
     1261 aaaatcaatg cacatgatct tatcaaaaaa aaacaggggt acaaattaat tgaaaaagct
     1321 ttgagatgaa agttcctaaa taaaaaagtt cagaatgata ggtaaaaaaa tgactaacta
     1381 ttctagtatt aggctatttg tattattctt ctgttatttt tatatcaaaa aatccagaaa
     1441 taactaaata taggtatttc tggcttatag tataatattt acgccacagc ccccaatgat
     1501 tctttttgga atcatgatca aggacggaca tacacaaaaa tattttgccc attcgatccg
     1561 aatagattaa cgactaatct agtaagtaat atagattggt acgtagtcaa accagcaaat
     1621 ggaaaagttg tctattccac cccaagggct ttaaagacag catcttccgg cgtttgataa
     1681 aaaatcaaat taaaggtacc cattaattct gggggtacag ttccaatatc agcagcgctt
     1741 atcataggta caagtacttt tttcgctccg gcatcttttg ctacttgtaa acagttagct
     1801 aaattatcta ccttaatcat agaaccacca attgtaatat cccctaaaat aactaaactt
     1861 ggtaatacag gtttatttaa ggaaactgag cataaagcta ttatagttga taacgataat
     1921 gtttttgtca taccaatgcc attcatatct tgaacatgaa cgacaaaatc ttttgtcgtc
     1981 aaactaatag actgactaac acttccataa ttagctctta aatatcggta tgccgaatcc
     2041 atcgcttctc ttgctccagc atctgaattg atcccagtac gttcaaactt tccatttccc
     2101 gaagtcattt gcgtttccaa tttataggta cctaattgcc cagttttgcc ataagatacc
     2161 gtgtacaaat gccctggctt ccctaaccct tctggaatca aagttcctcc accttgttca
     2221 ggaacagaaa catactcttc tcgctcttct tctaaatcaa tgtatgaaaa attgacatca
     2281 taaaattcca ttccaccaat tttctttaat tgttctttta cacgacgacg catttcaaga
     2341 gcaaatctta gtatttcttc gacatcactt ttttcaaatc taccatcagg atacaacagt
     2401 ttcatcatcc cagatacaat ccgacgaact gcaatcgtat cccgctgatt taattgagaa
     2461 ccaagtttga aatatttatc aaaactatcg ccaaaactaa cttttcgaag ctcacgcatg
     2521 acttcagaaa aataatctgt aatgaagcca tagtcatttg taaaaaaatc tggtcgatat
     2581 ttaggaattt cccaacctgg taaataacaa tgcatccgat ccaaaaaggc tgaatccgtc
     2641 cccataacct ccggaaatgg ctcaaataaa ttcgaagttt tcaatattac atcaacgctt
     2701 tgattaatat ttcctacaaa agccattgat gctgaagcat tcttttcttc tttgcctcta
     2761 gcaaaagatc ctgaagccat gtaatctttc atgatttgaa cgccatcatt atccttaaat
     2821 ttaatcccag caacttcgtc aaaagcaaca cagtcccaca tacctacaag tcccattgta
     2881 cgactagcca tattatagaa aaggtttgct actgttgttt gtccacctga aacaaggatt
     2941 gagtttggtg aaatttcttt atatacatgc gatttacctg taccacgtgg tcctagttca
     3001 cagagattaa aattattttc aattaatgga ataagtcttg ctaaatgaag ccattttacc
     3061 cttttattaa attgtgtagg ttccatacca atggaccgta gaagtaagtc aatccattca
     3121 tttgtagtaa actccttgcg agccatcttg taagcctcaa tgtctaaacc aggcatttgg
     3181 attggatcaa ccttttttgc aataaaaggg ctattccaac gatcattctc atcataccaa
     3241 tattccatcg aaacaataca ccagatcccc ccacctaata atcgatcaaa ttttttcgga
     3301 tactcttcac taatttgaac attttttaat cccaggttag agaattctgc ttcataacaa
     3361 tctttctttt catttaaatg tacagttact ttatcaataa ctgtataacc acccaattca
     3421 cgaatttttg cttttacttt ttctgcttca tcaggacgca catagtttcg agcaagaata
     3481 tttttaacat tttccacacc tttttcaacc aatgtttcat ccaatgacga agcatacata
     3541 ccaagtaaat attccaatac ataaacaggt acattcgcac cttctttaat tttctttgtt
     3601 aaatcttttc tgacaatctt tccgggaaag aattcagata actttaaaat ttcctgttgt
     3661 tccactagaa ttcctccatg tgttcagtca ttataatagc aattaaagta tatcatactt
     3721 aaccagtagg cttgataata caaaagaaaa agtatccaca aaaaattgtg gatacctcgt
     3781 ttttatatat caaaatcaaa tgattctgca aaaggattat ctataatgaa ttttattcgc
     3841 tcggtcaaat catttttttg attttttatc actaaataat aagtatcttc aactgtatat
     3901 cgacgattta caaattcaaa aacaaattta gtaaaccgct gatttgcatc ttctgttttt
     3961 gaatccgcaa catagatttc ttcatttgag atacgttcac catattcatc ttcaaaataa
     4021 agccagaaag atgcggggtc ataaacatca ctaattgcat ttttttgata gaattctaac
     4081 gtggttgata atcctgtaat tctgcggttg ctagtcatta attcaattgc tactggttcc
     4141 tttgcattgc tacctttggc taccgtaatt tctagaacag ggactagcat ttcttgaata
     4201 gatgaccctc catgaacgta gctttgtccc ccgccagctt tcttaaaaat acttgaagta
     4261 atcgggacac aaatgtttct agtgtcatca tttcctaaag aatctcccaa agagtaattt
     4321 ttcgtaccaa ttatttcgta ttcttcttca ctaagaataa aacgacgttc tacacgatct
     4381 ttttcatttc tagatggatt ttcaatctta tctacttctt caacgtggct tcttttataa
     4441 ataaatccat gatcagccgt aactataaaa cgatagatac tgccatcatt atgcaagcga
     4501 ttaataagtc gggaaatttc gcttatcgct aaatcacagg cctcaaaaac tcgattttca
     4561 ttcgagtgat cacctgttct atccacttga tcgtgataaa tataaatgac tgatttgcca
     4621 ttaaatactt ctcgtacctc agccttattc atcttaacca catcatcata atttaaagct
     4681 acagcatttg catctcgttg ctggagaatc gcatttcgat tggataaacc attcgttttt
     4741 ttcccatcaa tcagtacttc tgttccttca ttgtaagtta gttgattgtt tggtaataag
     4801 gcggctttac cgaattcagt aactgaaggt aatacagaaa gaaagctagc catgtttgtt
     4861 gaatacttct tttctctaac taacttacgt tctaaattca tccctaactc atatcgaaaa
     4921 gcatctgaaa taataactac agttttaaca gagcgtttca ttacagcttg attataaaat
     4981 tttcgaatgg atggacgatt cttaaattca aaagtttgat tccaaatttg tcctgattga
     5041 tcaagaaact tcgaataatt tgcttcaact aatcgataca attggccata tttttgcttt
     5101 tcttctatat gatcactatt ccaaataaat ttccgataat gcgtatcaac ccaatacatt
     5161 tccttctcat attgagttag caaattatcc atgttcatcg gcaagcacaa tctgttttta
     5221 tccacaagat aataagcatg tttcaataat tgatactcat aaatataatc cgatgcgaaa
     5281 tgcatttttt cgcgctgctt taaactatca aaaattgttt gtcctgcaat tttcgttgta
     5341 gtgtcagaag cctttaatcg ttctgcataa aacattaata tttttgcatg aatctcagaa
     5401 aatacgtctg cttcaattag atcatcaatt tctatactgt ctaataatcc atcaccatca
     5461 atagcctgat atactttttt agatagctgt tcaaagcttt ccatgtaacg tgtatcattc
     5521 ataaactgat ccatgaaagt aataatgttt gctttcaaat gtagtatttc aaatcctttg
     5581 aacttcttcg gcatctcttg atcaatttga taataaaaat agttcaaata aagacacatc
     5641 gtcagctttt ccaatgttgg ctggctatcc gtaaagccaa atttcatttg aataaattcc
     5701 caaaatttag ctgttaactg atacttatca agttccctta aaggattctc cctactttct
     5761 gtaaagcttt ttagaactac acgcagtaaa tcatttaatc gaatactttt cgatttcaac
     5821 aaaacagcca ttatcattaa ttcaatcgtt tctgatttat taattgtcat atgcgtacta
     5881 aattcaccaa aacttctcat gcgatccttt gcattaaaga aattacgata ctgtttaact
     5941 gtctgatgaa atctaagtgg aatagccaat tcattcatga taatcgctaa gcggtctgca
     6001 ctaaattcct ctgaataatt caatacactc aacaaatgat tatcttcatc tttatcatcc
     6061 caacgaggaa atggcgcata gattaaatag ttagtttcgg gatcttcata ttccaataaa
     6121 cgcttagttt taaattgtgc gtccttttct aatcgataga tttttgcatt ttgaatgacc
     6181 aatgagtcaa tttcttcaag aaaatcctga tttgaatcaa accaaaaaat gattttccta
     6241 catccataat taggaaaacg ttgatttaat ttttcttcaa tttgttgcgt atttatatct
     6301 gtcatcaatc tcacctaatc gttctctttc tatacccctt atattgacat aatttggata
     6361 atttcgcacg caatttaaga ataaaaaaga aagttgttag aaaacaactt tcttagataa
     6421 ctattttttt ggttctttga ccccttttgc aaaaatttgg aatttctcgc cggttttagg
     6481 atcacgctgc aacttatcat aattgacaat tacaccatca tctaagtcta attcaattcg
     6541 ttttaatgct aagtgaccca acttctcgtc atactcacga acttctttta attgcttctg
     6601 aatctttaca atttcttttg tcattgcatt tctttctttt gggttatcac ttgttgaaat
     6661 ttgttgctga cgcaattcga ttcgattgtc atacgctttt tgtagttcgt gtaggtattc
     6721 agtacgtact tttcctaatt gatctggtgt atagcgatgc aagtacatta acgctttaaa
     6781 gccattttgt tttcctgagt ccaattgcca ataaattggt cgattggagt atgtttttaa
     6841 atggtctttg taaaaatctt gtacgaagta acgacgaata atttctcgac ttgtcccttt
     6901 gccacctaaa gtgtcagcga taaactggag attttcttca agggtttctt taccaaaagt
     6961 aatctcaacg aaatcaatga aacgattgac aatgtcaatt tggctatcct tgaaatactc
     7021 atcatcggtg atgagtaaaa cattatcagt atcaggttta aatttttgat agcgggaagg
     7081 atcccattcg ccgccagcga agatgagacc atcttcgtct agggagtaac gaccgaagat
     7141 acaacctatt gaataagaaa taaaatcctt aatttccctc gccttatcag gtaaccttgc
     7201 agagatatat tcatcttgaa cctcttttgt taattctttt tcaagagaat aatgattaat
     7261 gaatatgtcg ttcagttcct cttcattcga ttttagagta ttaaattgat taaccaactg
     7321 cctacttaga cagttaaatg cctctgagag atctttttta aacatataac ttaacaaaat
     7381 gtttcttcta aactcgtatg acgtttcaag agcattatag tcttttctag ctatatcgat
     7441 attttcatcc actttttctc ttattttttt taattttctc tcagatgtaa ctttaagaaa
     7501 aggtagtttt cccattggtc cttcatggta atccaaggtg ggagaaataa aagttaaaaa
     7561 gtgattaact aatttagagt ttacatagcc aaatatttct tcaaagtcag ttatatcctt
     7621 tgagaacaga acagatcctt tagtttcaaa aattgcctga ttctgcaatc taaaagatac
     7681 ttgtccagat gaaagtgtcg accaagtaat tcccttttta aaatagtaat taagattttg
     7741 tggtctagat tttaacttcc cattttcatt aacataattt tttatttcat ctccatcatt
     7801 ctcccagtta accacgtatt cattgtttcc ataccatttt ctaaaacgac cacctttagt
     7861 tgtaggaaac catttttttc tagacttttt agcgtcctct aatgttttag catcaaactt
     7921 tattttgtta aattctactt caaaccaata ccgcaaaaat ttattgttat ttccggttgc
     7981 caacccttgt tttgcatctg caacatcgtt agttaatttt ccttgagcaa aatcagtgat
     8041 tacgttatcg cttgcccagt aagcaatcgg cattcctggg atttttttga agttgtcttg
     8101 attagtacta taaaaataat cgcattcacc atgctgatga attgcttcta acgttttaat
     8161 tttttgaact tccattccac ctttaaaatc tgataatttt atatagcttc catcttgttc
     8221 atttgaattt tttatcgtaa acgtacaaat tggaacggtt gcttcttcaa aagctgaata
     8281 ctccatttga atcaaactag aaatgtttct ttcattaatt aaaaatgagc gtaacttttc
     8341 atagctagaa atgaacatcc aaacaaatgg cgtcataaag gaagcatatc cattatcaat
     8401 cagcatttgg ctattcaatt taataaacac agaaaataga tcttttttga catcagaata
     8461 gttatcattt acatattttt ttaatttctt atccatttta ttaagataag gcggattagt
     8521 gactaccgct acatatttat caactagcat ttcagccacg tcaagaatgt gcaagtattt
     8581 ttcttgtatt tccttcatcc cataaagaat atccatattc gtaaattcgt tgaattttga
     8641 tatatactct cttacttttc ctaagtattc tttagttatt gcctgattat ttttatcgac
     8701 taacttaatg attgatccaa gttctttccc attttcaaat tgatcaaaaa ttaactcttt
     8761 gtattcattc cagcgttcac tatacttatc attgttcaat tcactaatac gctcttgata
     8821 ctcgtctgtc actttaggag aatcaataaa ctctcttaaa ttcggcgata gacttttttt
     8881 caaaaaaaga cgatcgtatt gacgcccttt catcataatt gcaaaataag acaattgata
     8941 cgctctttta tcgatttcaa gaccatataa attgtattca acgattgcac gtgcagcatc
     9001 acgctcagaa tatcctaacg taagataaat ttccatcaat acatcgaagg cgtaaactaa
     9061 aatatgccca gaccccattg cgttatcgat aatttttagt tcttctggtt ttaaattact
     9121 tacagatgtt gcttgttcaa aagcatattt atctggaatt aagtatttca acttatttct
     9181 taattcacta ttgggataat gatctaacca atactttcct aaactattgt caaccatata
     9241 acgaacgacc caatctgtgg taaatagttg agttgctgcc ggaatatctt gttttttgac
     9301 aatcccttta taaatattca ccacttgatt atgtggctca ctattatagt actgatacaa
     9361 ccacccaata atctctacct gtccaccagc ttgaacatag aaatcatcct ctggaatact
     9421 taaaagatca gcgattacac catctttttt aatataagaa gctgtaaaca aaagttctgt
     9481 ataatcttct acttcttcaa atagctcagg taagtaatca ttcaattgat tacagatttt
     9541 tataaaaatc aattgataca gcttgtccat tgcttctgct gaattatctg ttttccaagt
     9601 tctgacttgt tgctgttcat tactagataa ttcttcaaag atatcggcat cataaatatc
     9661 tgtaataata tctggctcaa ttttcccact tatttcacta gataatacac gatacgtgtc
     9721 aggtaaataa tcatttacct ccataaaccg aatggcaatc aatcggttaa accacgtata
     9781 agcaacctct tcgattaact cttgaaaagc ttctgaataa gaagtgacag aagcacgttg
     9841 ttttagttct gcaatcaatt tgtttctttg cgctatttct tttccttgaa ttcttattcc
     9901 tgatttttcg atttcttgta aattgctatc aattttcttc acatcttcaa tttttgattc
     9961 atcaattcct aaacgttttg ctttagtcat tacttcatca attaattttc tacgggcatt
    10021 gaccgcgaaa ttctttatcg ctttcttatc catttttctt tcccttctat atgtaacctt
    10081 tgaaaagaca ggcacctttt tatgcctgtc ttttcactag aattgaatcg tgatttctgt
    10141 attttcttga agttgttcct tcagtttttg attaatttca gctgttaact catcaatatc
    10201 tgctgctgac ttaatagttt taacatgaac gttaagtgtt ctcattggta ctgttttctg
    10261 ttgaatagta ggttttacta tcgctatttc ttcagctttt gctgcagagt ctatttcatc
    10321 tttttcagtt tcacgaatca agtttgctgc ttcaatttgt ttacgtgctt gttcttcttg
    10381 acgtctgcgg ttttcttcat tatcgaaacg ttgattaaag atcaaatact gttctgctac
    10441 gtttaatgat aagaaaacaa gatcatctat agtattcgct tgttcaattt ttgctttcag
    10501 ttcttgaaat tcttggtcaa ctattggtac aaattgatcc ttaaaatctt ttccttctaa
    10561 taatttaaat gttgcttgtt tttcttccgt taatttattt aatatttcct gactttccaa
    10621 ctctaacagt tgattatatt gttcaataaa ttcttgaatc aactcattta gtttcatcat
    10681 atctgaataa ggatcagcct ttttcaaaat ggttttcatc tcatgaatca attgatcaat
    10741 ttcttggcta gaagtttgac gccgactttt ttcgattaat ctaattttat cttgtgcatt
    10801 ctcccagatt tttttctgag tactattttg cttgtggaaa tttttaattt tatcatatgt
    10861 ttcagcccag tcgaataatt catcgcgata ttttttgatt gtataaaaaa agtcttcaac
    10921 atctgacgtt tgaacaatta cttcaagata tttttttatt tgctcatatt cataagcact
    10981 agggtaggta taagtgtttt gtaaatcaaa ataagagcgt aaattgtcta attgaccttt
    11041 taaatatttc ttgaaatttt ccattgtatg ttcattgtta ttttcatcaa caatattacg
    11101 actttgaaac agttctctac cgatttcgtc aaccaatttt tttgcttttg gcgaaatcac
    11161 cgcgcttggt tcaattttta tcttttcact ttctcgtcgt ttttgaataa tcattacaat
    11221 actatttgga tcatccatcc gtgaaatttg tacattgtta taaagtaaat caattttacc
    11281 agacatgaaa agtttagcga tgcaccattc cacatcaagt tctgtgaatc catacggttg
    11341 ttttgtttca aaacgatcac gaattgtttt catcgtaatc gttaggtgat ttctcttttg
    11401 atcattgata aaattgaaaa tttcctgaac tgcttgctca tttgatggat cttcaataat
    11461 ttcatttttg ctttctttca ctaaatataa gatatcttct ttttctttag gcgcatcaat
    11521 ttggtttaat ttatggtata cttcttcagc cattttctga agtgctgatt ggaattttgc
    11581 tttaaagtcg gagcctgtca gttgaatttc tgcaccgtta tagaaaaatt ttgcagattt
    11641 caacagttca tttaattgat cgttgatact tgcacttagt tcctgtaatt caccagattt
    11701 ttccgaacga atcgcgtcaa agttctttac tacactcgaa taagtcgttg ttaaataaag
    11761 attcattcta gcatacattg ctatatcatc tttaaattct ttatctgatg gcaattctac
    11821 gaataataag ttacgggaac tcttaagcgc aagttctgcc tcttgacctg ctaaatcaga
    11881 gtatggtgaa ataaaattaa ctgtcatttc agcatttcca gcttgcttgt atggacgttg
    11941 atctaacact tgtgcataag taaacgtata ccggttttta aatttatttc cacctgacat
    12001 gcctaatttt tcataggcaa aactatttcg gtctagaacg ccgtcaaaaa ttcgtttaga
    12061 tagttctacg atcaaatcac tatctgtaat attttgattt ttaatctcac gagtaatttc
    12121 ctgttcttca tcagtttgga aaatataact atctaagttc ttccgcacaa agttttcctt
    12181 aattaaaagg tccaatgctt cttctactcg ttttttagtt tccaggcggt cttcgttgat
    12241 atttcttatc atcaagctcg taatattttc aacatttggt ttgatggctt gatcaacata
    12301 tttaatcatg aataaaattc gtaagacatt tacgttaaag ttatctatat cagttggtct
    12361 ttgaatatga gaattatttg tagcttgtgt aatcactcgg ctaattgctg tatcaatcca
    12421 acgttctaac gagtaataaa actgatctaa agaaaccaaa ctggttgtat cattttcctt
    12481 atttcgttca gcggcttctt taaacattgc tagtaatgaa cgttcaccag acgataagtt
    12541 tgatccttga tagctgtgat tacgaatctc ggttagaatt tgccccaata aattgaattg
    12601 atagggaata aatggataaa cttctgcgta attttcagca tcttggaaga gctttaattc
    12661 aggactatca acaaagagta atttattttt caattctgtt tgaacagttt caaattgtaa
    12721 ggctaaagaa tcattggcaa actctttttt cttcaaaata cgttctttaa ttacttcatc
    12781 ggcatttgct gaagataaac tcacagttgt ggcaaaacga tccttgatct tagaaaaatc
    12841 attatcagaa ttgttatcaa agtttgttac gtgatcaatc gcttcctgac ttgtcactaa
    12901 tacccaagcc ttaccttcac aaattcgacc caaatcttcc acaacggttt gtaactgcaa
    12961 agtcaactca cgattaccgc cgatatattg tccgacctca tcgactagaa aggcaatatg
    13021 atggtctgct tctttggaat caagatagct tttaactaga tttgcaaagt catcaatgct
    13081 tattaaataa tttcctgatg ctttttctaa aaaattatca atagcggctt cactcataaa
    13141 atcgatttta agtgccgctt ctttgatatc atcttggatc caatcaaact catggcgctc
    13201 ttcttgccat tttgccccat taatctcttc aaaagcagct ttgaatgcat caaacttttc
    13261 ttctttaatt aaccgacgtt caaaatctgc tagatgtgga atcgtgctta atccttgcat
    13321 ttcgttaaat acctttaaaa aaacattcac gattccgttt ttgtcttttt taccacctgc
    13381 atcacttttt gaatcaatat taaacagaat aacatctgta tttatttgtg agcaccgttc
    13441 catcgttgcc aaagtcagtg gatctttgat tttcccatct tctttgaagt aatcaatggc
    13501 tttcttgtca tttatttctc gatttgcgag caagtaagaa ataattttta agaaatgaga
    13561 tttacctgaa ccaaagaacc cctgaatcca aacacccatt ttatctgttg gtgtattgat
    13621 actccgttgg taggcatcaa aaattgtttt aaagtgtttt tgtagttctt tcgtaaccac
    13681 gtattcttct aattcttgtt gaacattttc atcctttgct tgaccgacct taataactcc
    13741 ttgaatattt cggtcaattg gttttgcaaa aatatcttta attagcattt aatctcctac
    13801 cttccatccc aactaaattc taaatgctcg ataataatta tcatctttat tggtattaag
    13861 aattgtcaaa cttaattcat catattcccc tggatacatc atcacaactg gtacgcgatc
    13921 aaatacctga tgcattttat ttaaaataga gtgcgctcta attaatggat ataattcgcc
    13981 aattcctgtc aggaacacaa ctgatttttc tggtgtatgg gcatccacat attcaaaaaa
    14041 tacattttct tcctcaggta aatccatttt caataaacga ccaatgcttt ccactaattt
    14101 ttgtaaacca cgtcgttctt ccatcttaat cgctttttca gtgaaaccgc gtttttctag
    14161 atactctaac ataatcacat agagattata aactttcact tcataattat caccaacaga
    14221 tgttccagat atatcattaa tataatctct tacaattaac tcgtctttcg gatcgtagtc
    14281 aaagatataa tagcctactt cattacctaa accacgattc aataaaaaat cttctttttg
    14341 aattacttca ttcaactttt ccaaatgctc ttgaatcgat aatgacatta taaaattcct
    14401 cccagtgcta gtacaatatc tttacgattc ttgtcaacta accattgaat caatcgttta
    14461 tctaataata tcggagtcat tcgtccatat tctttttccc ctctgactaa tcctgtttca
    14521 attagattcg tttgataagc ggcaataagc cgtttaatcg tataatcttt ccattttgaa
    14581 atatcttctg aacttctccg cttctctgta aaaaaagaac ggtaatcaac tggtgttaat
    14641 tgcaaatttc ctttacgtag attttcagca tatacctcag tcataaattc attaaaaaga
    14701 tcatcaatca taaggatgga aatcaaattc actaactttt gattatctat atttaactga
    14761 ttgaaaagtt gcaatccagc ttcatccagt tgactaactc tccttttcac gttctgatag
    14821 atttcttttt gacggttact gctcactgca aaaaaaatat tttcatgttc atttttctct
    14881 ttaatttcta tatctgtata tccttctagt cgtaattgaa tatataactt gaactctgaa
    14941 aaccaaaagc gtttagaaac tagaccagca gaatattttt tattcaatag attgcctcct
    15001 aatcatctat aattcaataa gtaaacaagt gttttttgct catcgttagc attcattttt
    15061 tagtatctac tatacaatac atatttatta tag
//
LOCUS       DADGKS010000066        14815 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.067, whole genome shotgun sequence.
ACCESSION   DADGKS010000066 DADGKS010000000
VERSION     DADGKS010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14815
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.067"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(296..1024)
                     /locus_tag="JXV47_002217"
     CDS             complement(296..1024)
                     /locus_tag="JXV47_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1488235.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(1002..2576)
                     /locus_tag="JXV47_002218"
     CDS             complement(1002..2576)
                     /locus_tag="JXV47_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAX1488236.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDFQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEAKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            2805..3743
                     /locus_tag="JXV47_002219"
     CDS             2805..3743
                     /locus_tag="JXV47_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1488237.1"
                     /translation="MKLKKGLLGNLKKNRALFIMLLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSSVGFVLILITNKIVNKLDPSSALF"
     gene            3755..4666
                     /locus_tag="JXV47_002220"
     CDS             3755..4666
                     /locus_tag="JXV47_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAX1488238.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            4690..6162
                     /locus_tag="JXV47_002221"
     CDS             4690..6162
                     /locus_tag="JXV47_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAX1488239.1"
                     /translation="MKKNMQKYLIGGASVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            6213..6824
                     /locus_tag="JXV47_002222"
     CDS             6213..6824
                     /locus_tag="JXV47_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAX1488240.1"
                     /translation="MNENKWTKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFRILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            6854..8767
                     /locus_tag="JXV47_002223"
     CDS             6854..8767
                     /locus_tag="JXV47_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HAX1488241.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLALMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            8895..11876
                     /locus_tag="JXV47_002224"
     CDS             8895..11876
                     /locus_tag="JXV47_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 42"
                     /protein_id="HAX1488242.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGSGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            11873..13534
                     /locus_tag="JXV47_002225"
     CDS             11873..13534
                     /locus_tag="JXV47_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HAX1488243.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SANLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            13574..14506
                     /locus_tag="JXV47_002226"
     CDS             13574..14506
                     /locus_tag="JXV47_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HAX1488244.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
BASE COUNT         4815 a         2333 c         2978 g         4689 t
ORIGIN      
        1 atttaaataa ctacatccat ttattctatc ttctaaaata gcctttttca tttcagttaa
       61 atagttcagc gccatttttg cactcgactt gcatagtagt tttttccata ttcctcaacc
      121 tcagcggggg ttgaagacat aaggaaaatc ctatgcgtta tgctcaactg gatctgatta
      181 aatattctaa tgtatttttc tctaccatca ttaaatggtt aatagccaaa aatcaccact
      241 tttcaatggc tccttgttgt ataagtataa ctagaagatg aacacgtctg agaaattata
      301 gaagcttttt acggtaatta ctggggctgt gtccagtagt ttttttgaag agaacagaaa
      361 aatagctcac gtgatctatt cctacttttt gactaatttc atcaatagat aagaatgtgt
      421 ctttcagtag agcacttgct cttttgattc gaaagtctag caagtaatca tgaaaggaat
      481 aacctgtttc ttttttgaag gcccgtccta aataagcggg atggtaatgg aattgtgtag
      541 ctacatcttt gagcgtaagc ttttcactat aattgttttg aacgtaatca atcacttgtt
      601 gaattgactc attaaaagaa tcatcagtta gagagttttg attagctgct gatttacgca
      661 ttttttcttc ttgtactaac ttaactaaat aaggaaaatc aatgggtttc gttatgtaac
      721 ttttaataga taaatcaatc cccttttttg catactgaaa attttggtgg gcactaatga
      781 caatactagt aaagtagcga ttggatgttt gttgcaaaga ttcgattaat tcgagtccag
      841 aaattttccc catcgtaata tctgtgataa gtaaatcaaa gcgctggttt tgcaggtttt
      901 taaatgcttc gtctccgtct gtgtagcagt gatcgataat gatgtcgggg actttcttca
      961 aaagataatg ccttatgcct tctacaattg tacaatcatc gtcaacaatt gcaattctca
     1021 acatgcatat tccccccttt ttgtattttg atagtaatcg ttgttccgac gtgtagttgg
     1081 ctttctataa caaaacgtgt atctccagga tagagatgct ttatacgtcg aaaagaattt
     1141 gagatgccga tattctcact ataaggaata tcatcattaa gtttttgttg aatatgctcc
     1201 agcttgtctt ggtccattcc tttcccattt tcaacgattt ttaacacata atggttggtt
     1261 gtttcagttg catagacagt caaacgattt tccttttttg atgaatcgaa gccgtgttta
     1321 atataatttt caacaaatgg ctgtaaagaa agttttggta acattaattg atcaatatga
     1381 tcaatcagct gatagtcaaa gttatgtcga taacgacgtt gatgtagttg caaggagagg
     1441 tcgatattaa ttaattcctc tttcaaatca attatgtcgg gctgatatgt attattgcga
     1501 tacaacttgc tcaataaata tatactgtcg ctgatttctt cgtcatcatt caatatggca
     1561 gtcattcgaa taaattccaa attattaaat agaaaatgag gctcgatttg atattgaagt
     1621 gctgcatact ttgcttcttg cttcaaccaa ttattttcat aaagtgtttt ttgatatgta
     1681 gcattatcta aataaaactg attgatatgc atagcgattt ctttcaaatc accgactttg
     1741 ttttcgatat tgattgactt gtagtctcct gtagatgaat gatttaagga agtaatgatt
     1801 tcctgatact gctggatata gttacgaaaa cttctattta ataattgatg aatagcaaga
     1861 ataaacaaac tcattaataa gaaaatcatg attgccagac ctaataaggt ttgtgacgaa
     1921 taatttggat tttcatatac ttgtaatgtg tggttaccga tagctatctg ttgcgttttt
     1981 ttccatttag aaggcgagat gtcttcagat aaattgacgg aatcaatacc attagacaaa
     2041 gaataattgt aatgtgttgg aaagagactc ttttttagcg cgttgatcga aacgtctaga
     2101 atcaatgtag catcgggcat gtcctcacta atgaaactta atgaacgaat aaaagaaatt
     2161 ttttcgtttt ttgtaggtgc gtaggcactt aagtattttt cgtaatctaa tgagatagat
     2221 atatttttaa cttcatcatc ttgcacaagt ttttttaagt tatctactaa ataggtaggg
     2281 gagcgatcct ttgacaaaat atcttccatg tattcagcag gtgatgagag gtagtagtca
     2341 ttaaggtttt cttggaaatc ataattttga tagatctctg tcacgatacc ggagagaata
     2401 cgattatatg tttccatata gtgggtgatt tgctgaatgt tttgcaggtt ttgatttttt
     2461 tctttttcaa tcacattgat ataggaaaag aacaatgtga aacaggcaag taaagtaata
     2521 aaaaaaatca atatgtatgt aaaacgcata ataacttttg ataaatcgtt tttcattcaa
     2581 agtcctcatt ttgataatct ctaattttat gaatcattat agcacatatt acaagtgatg
     2641 taaacgcttt gcaaacaggg ctacttatga ttgtgaatac agtttccgtt taaaaactat
     2701 tctattgtag aggtttaata aactaaaaat aatgtataaa aaattaatgt aagcgattaa
     2761 ccaagtgggt ataatcaagg aaacgctgag agaggagaga caaaatgaag ctaaagaaag
     2821 ggttattagg aaatctaaaa aaaaaccgag cattgtttat tatgctttta ccaggtgcgt
     2881 tatggttatt tatattttgc tatataccaa tgtttggagt tgtaatcgct tttaaagatt
     2941 tcagaatttc atcaagggga ttctttacaa gtttgttcaa cagtccttgg gttggctggg
     3001 aaaatttcaa atatctcttt gcttcgcaag atgcttggat cattactcgc aatacggttg
     3061 tttataacgt tgtaggtatt ttgctaagta ctttttgtac agtgtcatta gcaatcattc
     3121 tgagccaaat ggcgaacaaa cggttattga aaaagatgca gacatttatg atttttccta
     3181 attttttatc atgggtagtc atcagttact ttgtttacgc atttttgagt acggataaag
     3241 gattaattaa tattttacta agcaattttg gtgtggaacc cataaattgg tatagtgaac
     3301 cgaagtactg gccttttatt attgttttta cgagtttatg gaaaggcgta ggctatggat
     3361 ccatcattta ttacgcgtca attatgggga tcgatactag ttattatgaa gctgctttag
     3421 ttgatggtgc cagtaaatgg caacagataa ggaatgtagt cttgccacat ttaagatcga
     3481 ttattgtcat tatgttgatt ttgtctgttg gtagtatttt tcgagctgat tttggattgt
     3541 tttatcaatt gccaagaaat tcgggggctc tttatgatgt gacgaatgta ttagatactt
     3601 atgtctaccg tggattaatg aatagcggag atatcggaat gtctacggca gcgggattat
     3661 atcagtcatc agttggcttt gtcttgattt tgattactaa taagatagtc aacaagttag
     3721 atcctagttc agcactattt taggaggaat caaaatgata tcaaaattaa aacggcagat
     3781 gtacttttcg ctgccagtcg aacggttttt cacaatatta ctaatcttat ttactcttag
     3841 ctgtattttt ccctttattt tcgtaatcgt catttcatta acagatgaaa aagcattaca
     3901 actcaacggt tacgaattat tgccggctca atggagcact gatgcatatc aatacttaat
     3961 acaagatggc ggacagttac ttcggtcatt aggcgttaca attatgatta cagtgattgg
     4021 aacgttgatt actgttttta tgacgggaac ctatgcttat gttttatcaa gagcctcttt
     4081 cccttaccgg aagttcttta ctttttatct tttttttacc atgttatttg cgggagggat
     4141 ggttccttct tacttagtga tgacgaagat gcttggctta aaaaatacaa tttgggcttt
     4201 gattctacct cttgctttta gcccatacaa tgtcattatt ttaaggacat tctttaagaa
     4261 gtcgattcca gaatcgatta tcgaatccgc taaaatggat ggctgtagtg agtttcgagt
     4321 ttttttccaa atcgttttgc ctttagcgat cccaggggtt gcaacaatag gtttattttc
     4381 aagcttaggt tattggaatg actggttcaa cgcattgctg tatattgaca ccaacaaatt
     4441 gattccattg caatatttgt taatgaagat tcaaaattca atggaattct tagcaaataa
     4501 taatgacatt acattagcgc agcaacaagc aattcaaaat agccttcctc aagaatcaac
     4561 acgaatggca atggtcgtag tagctacttt accgattgca attgtttatc cgttcttcca
     4621 aaaatacttt gttcaaggat tgacgatcgg tggagtgaaa gaataaaaaa gaataggaga
     4681 tgttaaaaga tgaaaaagaa catgcagaaa tatttgattg gtggtgcttc tgtactaacc
     4741 cttggcctat taggtgcttg tggtagcagt aatggcgaag caaataatga aacaggaacc
     4801 acaaaagtta cttggtatca ggttggagaa gaacccaaag attttgatga ggtcatgaca
     4861 aaagtcaacg aaaaattaaa ggaagaaatc aatgtagagt tggatatgcg gctgattccg
     4921 gacggggatt atcagcaaaa gcttggtgtg atgatcaatt caggagaaga atatgatatt
     4981 tgtttcgtca atggcacaga ttatgtgaat tatgggaaca aaggtgcttt cattagtctc
     5041 aacgatcatt tggataaaga gttgaaagat tatgcagctg aattgaatga aggatttatt
     5101 gaaggtgggg caattaatgg cgaaacttat ggattgccag tcaataacga tattgccaca
     5161 acggaatatt ggacctttaa taaagatttg gtagatcaat accaattgga tgtagagaat
     5221 gttgaaggtg tagaaacatt ggctccagta ttagaaaagt ttgcagaaaa aaatactgat
     5281 acgaatatta cgccaatcgg tatgacccgt accagtgtct gtattcctta tgacaatatt
     5341 atcggtggtg gtgtaccgct agcggttgca tttgaaggcg atacacaaac agttgttaat
     5401 acttatgaga ctccagaaat gatgacttat ttgaaggcta tgcatgagtt ttataaaaaa
     5461 ggatatattt tgaaagatgc agccactgtt acgacagatc catttcgaat tgatagtaaa
     5521 aactggtttt taggtcgtaa ctcaagtggt tatcaaccat tagcacaaaa aaaattagaa
     5581 gctctagcgg gacatggatt aattttaaaa ccagctggaa aagcttttaa aacgactgga
     5641 tttgcaagag tggcaatgca tgcggtatct gcttcaagta aacatccgga agcagccttg
     5701 aaattgttga attatgtgaa taccaatcaa gaagtagcgg atttaatggt ttatggaatt
     5761 gaaggaaaac actatgatcg caatgaagat ggttcgatta ctttaacaaa ctctgatgat
     5821 tattatcaag gcgcttgggc attggtaaat acttatctag tttcaaaaac ttcaccgatt
     5881 acagaagaaa gtaaaaaact agaagaagaa agtaaaaagt ttcaaaatga agcaccgatg
     5941 tctcctattt taggtttctc ttttgacgct tctgattttc gaacagaaat tgcaagtgta
     6001 caaaatatcg tgtcacaata tgaagtactt ttaagctcgg gaacagttga ccctgaacaa
     6061 tatgtaccag agttgttaga aaaactagaa aaagctggat tggataaaat tcaggcatct
     6121 gctcaagaac aatacgatga atggcgaaaa tctaacaaat aattttttac taaatgaaaa
     6181 gaatagacta agcagttagt ggggggattc aaatgaacga aaacaaatgg accaaaggat
     6241 ttaattgggt ttttcaattg ttgttactaa actttactta ttttatacta atttgtttag
     6301 gatttggaat tttaggtttt ttccctgcta cgatagcttt gattgctggc gttgtgaatc
     6361 gaaaaaaata tggcttgcaa gagtctgtga agttcatgag taaaatctat aagaaaaatt
     6421 ttgttagata taatctatat tgctggtcag caactttgtt gttggccggc aatattacta
     6481 cgatctggct ttgttggcag caaagcgcac cattgtttta tttattaagt acattattat
     6541 cggtaattac actgttccta gtctttgcaa tgttgaattg ggtcgtgatc aaaagtcttg
     6601 ggttgtggat gatgggagac cgactgattg actatttgct tttcacagca acgatgttgc
     6661 caacggtagt catgcaaggc ttggtgcttg gaatttattt ccgaatattg atgattttgc
     6721 ctgtgatttt tctgtttggc ggaacagctg taacggtaat attgattagt aaattaactg
     6781 aaagagcgtt agcaaagttg ccttgtcaga tacaatcgca ctaatttttt cacaaaaagg
     6841 agtatttctt tctatgaagt taactgataa acaagtagct aatatagcct ttatccagca
     6901 acttgagatt ccattgacac aaaaagatga agaacaaata gacttgattt ttactgacac
     6961 aaaggctaat gtgcgacaaa tcaagattac taaaaatgag cagcaacgaa tttgcttgtc
     7021 ttattcacat gaagacttgc tgtatcgagg attgtttatc tgccttccac gttttttagc
     7081 tcaaggagga gagatgccat acattgaaga aacctcgatc attgagacca gttattcatt
     7141 agatgcttct cgtaatggcg tgatgaataa agagactcta aaaaaattca tttcttactt
     7201 agcgttgatg gggtacaaca cattgtatat ttacacagaa gatacctatg aagtagaaga
     7261 ccttccatat tttggttacc ttcgcggagc gtatacaaaa gaagaagtga atgaaattgt
     7321 tgaatttgct tctggttttg gcatagaagt agttccatcg atccagaccc ttgctcactt
     7381 gacccaattt ttgaagtggt atgctcaaca agaactgatg gatgatcaaa atactctact
     7441 gatcggtgaa gaaaaggttt atgcggcaat cgaaaagatg attattgcct gcaaagaaat
     7501 gtatcagaca gagcgtattc atttgggaat ggatgaagcc tatcaagcag gtctgggacg
     7561 atatttaagc ctgtatgggt attgtgatcg gacaacttta atgattcaac atatggaccg
     7621 tgtgttatca attgttgata aatataagat gaaaccaatg atttggagtg atttcattta
     7681 taagctatta gatgaaaccg gtaaagatag gtattacaat cctgatttta aactcaaagc
     7741 attagcagct aaaggattac cagcaggatt aacctatgtt cattgggact atggttcaga
     7801 tgaagtttcc tcctatgaga aagtaattga taaccatttg aaattttgtg acattgatca
     7861 ttacgtttta gctagtggtg cccatatctg ggggagacta gccccgaatc atgggaaaac
     7921 agaagcaatt gtttctgcag ctgtaaaagc ttctaaaaat aaaggtgtac gttctgtgat
     7981 gttaactact tggggagatg aagggcagga aacagagcat tggcattcct taattggggc
     8041 attaaaatta gcagattatg tctattctga agaagagtgg aatgattttg aggaaatcta
     8101 cgatcgttta ttaggaacag gtagttatca attaatgtcc gaattacgat atttcgatga
     8161 agtggatacc attacaaata acaacttaca aatggcttcc gtgagtaaac tgctactttg
     8221 gcaagatccg ttagttggta tatatgactt tcatgtagcc gctcataaca aaattgccac
     8281 tagaacaatt ggtacttatt atcatgagtt agctcagaaa ttagatatga ataaaaattg
     8341 gaatccaaaa caaccaattt taacaactat tcgtcaacga tatatacttt tagctgaaat
     8401 tttagcacaa aaggcagaac taggcatcta tttacaacac tgctgtctgg tagaagacct
     8461 tgcaggatta atggaattag cgaatcggtg tgaagcacta gccaatcgag taaatgaatt
     8521 ggcatctatt catgaaataa tttggtatca aacatacaaa acctatggtt gggaagtatt
     8581 agaacaacga tatgctgcat tagctcatcg tctgaaaacc gttgcgcgtc gtattaaaaa
     8641 tcatcttcag gggcaagatg ccctagagga gcttttggaa gaacgattac cgttttgtca
     8701 atatcaagtg ccgcttgaaa tttctggctt taattatcgg caaagctcgg tgtcaggcta
     8761 caattaacga aggaatcttc ccgttgaacg gaccacttgc tcatctaatg ggaaagtggt
     8821 tcgttttcta ttcataagta gcttaccact aactctttta ttaagaagag aaaaaaagta
     8881 ggaagtgaga aaatatgtta tcggactatt atcaaaatct gtcagttata agtgtcaata
     8941 cagaaccatt acgtaattat tatattcctt atgcaagtaa agaagaagca aaacaagagt
     9001 tagaaaggga aaaaacgagc cagtttatcg atctcaatgg tacatgggat tttcagtatt
     9061 atccttctgt ccaacagtta ccggaaaatt tttttcaaga ggcctttact gaaagctatg
     9121 atagaatttc tgttcctgga gtttggcaaa cagagggatt tgacttacct cagtatatca
     9181 atgtatctta tccaattcct tttgatccgc cttatgtacc taatgatacc ccttgtggtg
     9241 tatatcggcg tcagtttcaa attgagcaaa cagatgcacg cttttactta aatctagaag
     9301 gagcagatag taattgtttt gtttggataa atagaaactt tgtaggctat gaccaagtga
     9361 gtcatagtac atctgaattt gatgtgacca agtatttaca ggttggggtt aatgaaattc
     9421 aaattctagt gatgaagtgg tgtgatggta cctactttga agatcaggat aagtggcgaa
     9481 tgagcggtct atttcgtcca gtgtatcttc ttcaacgacc aactatgcat ctgacaagtt
     9541 atcaactacg gacgttgact gatcctaaaa aaggaagcgg aacattaatg gtttcttttc
     9601 aacgatttac tcctattgaa gtatcgttac ctatttctta cgaattattc catcctgatg
     9661 gacgtctcat agcgaaaggg gagtgttact cggaacaaca aataaatttg gatgttgaag
     9721 attgcctttt ttggacagca gaaacgccta aattatatac attactttta acatgtaatg
     9781 gtgaatattt taaagaaaaa gttggctttc gagcactgac gatcaagaat cgtaagttat
     9841 tgctgaacgg aacacctatt aaattatatg gagtcaacta tcatgacgtg aatcagcaag
     9901 gcacgccagt gatgacccga gagcagttac gtgcagattt gttattaatg aaaaaattaa
     9961 atgtgaatac tgtacgaacg gcacattacc ctaaatcacc agatttttat gaattggcgg
    10021 atgagattgg tctgtatgta atcaatgaag cagatttgga gtgtcatggt gtggttaatc
    10081 tatatgatac tgaagcgaat tatcaactaa ttgctaatga tccgacattc gaaaagccga
    10141 ttatggaccg agtgatccgt tctattcttc cttatcaaaa tcgaagctct atcattatgt
    10201 ggtctatggg gaatgaatct ggttatggag taaattttga aaaagctcaa gctttagcac
    10261 ggaaattgga tgattcacgg ttgattcata atgaacgctc gattgaacca gttattgacc
    10321 aagtgaatga ttttagtaac ttggatgtta ttagtcaaat gtatccccca ctggaagatg
    10381 ttcatcgtca ttgtcaaaga agtgatactg aaaaaccttt ttttatgtgt gaatatagcc
    10441 acgctatggg caacggtcct ggagatctta aaacgtactt cgatttgatt caacagtatg
    10501 attcctttct tggcggttgt gtctgggagt ggactgatca tgcaatcaat agaggaactt
    10561 tagaaacgcc atcttattta tacggtggtg attttggtga aaaatatcac gacggcaatt
    10621 tttgcgtaga tggtttattg accccagatc ggcaattaac agtaggtgca ttggagtacc
    10681 gtaatattca ttcgcctatt caactgattg ctgtagatga ggagctgcaa gaagtaacct
    10741 tgagcaatat aactgctttt acagccggtt cagcatttaa cctttctctt gaatggtata
    10801 tagatggaaa aaaaacagtt tatgaagtaa tgaatccttt catacttgag cctggcaaaa
    10861 gttgttcatt gcccatcaca gtacctacaa cgattcatgg tgctcatacg gttgctgttt
    10921 cgctatctgt ttataaaaat gatgagcttt atggacagca acagctcttt cttaaaaaag
    10981 aaaaaatgag attgccaaga actgctcatc ataatgatgc accacaaatt tcagtaaaag
    11041 gcacagagct gataatcaaa ggagaatcct ttatttatat atatcaatta gcaaaagctg
    11101 cgttcacttc tgtaaagatc aatcaaaagg aacttttgga acgtcctact caattttcaa
    11161 tttggcgtgc accaacggat aatgatcgta acttagtaaa caaatggaaa gcagctggat
    11221 atgctgaaat gtctttagaa atcagaaaaa aagactggaa attcgtagat gatcatctcc
    11281 tgatcgaaac gtcttatcga ggagttattc caggattaca gccaattttt acaatgcaca
    11341 tacagttgaa aataaatggt gcaggcgtaa tcaaccaaaa agtatcagtg gagaaaaatc
    11401 cgatttttcc agatttccct cgctttggga tggactggcc gttgaatgat actttttcga
    11461 aggtttctta ttgtggctat gggccgtatg aaagttatcc tgataagcac tatgctgcga
    11521 tgtttggtat ttatgagatg gagattgagg aatttgatca gccatatatc aaaccacaag
    11581 aatatggtaa ccgctggcaa tgtgattggg tatcaatcaa aaatcatcaa ggatctacca
    11641 tgacggttta tggaaactct aatttttctg ctctgcctta tagtcaagct caattaaccg
    11701 aaaagtcaca ccattatgaa ttaataaaag aaaatagaac ttggttcaat ttaagttata
    11761 aacaaaatgg tatcggctca cacagttgcg gtccttattt agaagatcgt ttccgtttta
    11821 tggaagatac ttttgactgg aatatagtga ttactttcaa aggagaaaat agatgaaaga
    11881 aacaaagatc aatcaagtca aaaaaaaatt atctcgttat caagaagttg tttatcgaaa
    11941 ccattgctta aaatggtcaa aaaataagct gaatgttcgt tttaatggat tattttatcg
    12001 tttcgaacag ttagaagaag tctggaaacc ggtaacgaat ttccaatcat gtcctgtaca
    12061 gctcataaat gatccaaaag aaacatacga tttatgtata acacaccttt ataaccagca
    12121 tttgaaaaat gacggatttt atttaaaggt tactaatgac aatcaactta cgattgaatc
    12181 agcaaacctt cgagggtttc aatatgctat ggaagcctta ttagagagtt ttttttcggt
    12241 aggagatcaa ttattattac cggaattgat tctgaaacat gaaccatcag tgaaaattcg
    12301 aggaatcatt gaagggtttt atggtatccc ctggacacat gaaatgcgcc tctctctttt
    12361 ttcatatatg aaagataacc aattgaatac ttttatgtat gcccctaaag atgatgaatt
    12421 attacgtaaa aaatggcgtg aactctacga tgcgcaagaa ttagacaaat ttaaggagct
    12481 tttatctgct gctgaggcta gcaatatcga tttttggtac ttaattagtc ctggaaatga
    12541 tattgatatt acgtgtgaag aagacattca agttcttctg aaaaagttag aacaactgat
    12601 tgagcttggc gtatttcaat ttggtctatt aatggatgat attgactatc aattaaaagg
    12661 tgctgctaaa cgccgttttc gagagccagc attcgctcat gcctatttag tgaatcgagt
    12721 agaggaatat cttagcactc ggttgtccaa tcatgaatta gtcatttgtc ctacagaata
    12781 tgataatcgt catggttctc gctatttagc aacgttaagt caagaaatac cagaacaatt
    12841 accgttcttt tggactggcc caagcacgtt agcggcgtca atttctacag aagagctgca
    12901 ggaaatggct tctgtctatc aacggccgat gctgatttgg gataatattc cggtaaatga
    12961 ttatttagag gataaagaac tattgttcat gagtccatat gagaatcgaa caccgaatct
    13021 ttctaaggag agataccagg ttacaggagt agtttcgaat ccaatggctc aattagaagc
    13081 ttcaaagttt acgatcaata gtatggctaa ttacttatgg aactgtgagc gttttgatcc
    13141 tttggaaact tggacgtcag tcgttgaaaa agtagttgga agtaaactac aaccagctta
    13201 tcttacctta accaatgctt ttccaaatca ttacacaagc agtctgcttt cagatgaaga
    13261 attactgcta gccaaagacc cagaatgggt cacaaaagaa atggctgctt tagtccaagc
    13321 agtaaaatgg atccagcaag aacaacatac atctagattg agaacagaat tggagccttg
    13381 gttacaagca atcacagaaa gttggacttt ctggcaagaa tggcaattaa aaaaagatcc
    13441 aaaagaagca gaagaatggt tggctaagaa aaaaacacac cgcataggac gtgatttagt
    13501 aactgcccat ttagagcaaa ttatcaaaag ttagatatct taaaaaataa aaagcaagaa
    13561 aaaggagaac aaaatggtca agagattaat tagtgcaaac tacagtgatg tcaagaaaat
    13621 gacgtcaaaa gagttgaagc aatccatcaa agcgagtgaa ggacgggtga ttgtttgtga
    13681 aacggttgct aatactcttc cacaatctgg agaaattacg aatgcagaag ttgcgtcagc
    13741 atttggtgca gatttgattc ttttaaatgg tttcgattgt tatcgtcctg cagtttttgg
    13801 actaccaaat gtgacgattg agaaggtttt tgatctacag caaacgattg aaaacccgat
    13861 tcctaaatta aaagaactag tcggtcgtcc tgtgggaatt aatttagaac ccattgcccc
    13921 taaaacaaat atgatgagtg agaaagtaga aatcagccaa ggaagagcaa gctctgttga
    13981 aacgatacaa aaagcagaag aactaggagt cgattttatt tgctttaccg gtaatccagg
    14041 cactggagta accaatttag aaattactaa atccgtaaaa atggcaaaaa agtatttttc
    14101 gggattgatt attgctggga aaatgcatag cgccggctca gaagagccag ttgtgaataa
    14161 agaggcgatt atttcttatg cggaagcagg cgcagatatt ttactagttc cttcagtagg
    14221 gtctatccca ggctttttag agcaagacct aattgaagcg gttcggttgg caaaaaaata
    14281 tgatttgtta acgatgtctg caatcggtac tagtcaggaa agtgcccgac cagaaacatt
    14341 gcggcaatta gccattatga ataaaagttg tggtgttgat ttacaacata ttggagatgc
    14401 tggatacggg ggattggcac cagcagaaaa tattttcgaa acctcggttg caattagagg
    14461 aatgcgacat accatcaact gcgttagccg ctcgatcaat cgctaacaaa attaaataaa
    14521 aaatggttaa attgattatt taagtgggaa catacttgag atatcagcta acttctgtca
    14581 ctttaaaaaa gggactgtga cagaagtgaa aatagacaaa aaatatccga acaagagact
    14641 aggatagcag aaaaactatc gttttgcaac gaggaccaac tggaccgtag gagcaattct
    14701 cttattgttc ggatatttcg cttgttcaag gacttatgtc tgtagtgccc ttttttggta
    14761 ggaaaaatgg tagggaacca tatcattttt aatgaaaatc aagcatttca aaagt
//
LOCUS       DADGKS010000067        14811 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.068, whole genome shotgun sequence.
ACCESSION   DADGKS010000067 DADGKS010000000
VERSION     DADGKS010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14811
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.068"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(268..834)
                     /locus_tag="JXV47_002227"
     CDS             complement(268..834)
                     /locus_tag="JXV47_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAX1488245.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(834..1790)
                     /locus_tag="JXV47_002228"
     CDS             complement(834..1790)
                     /locus_tag="JXV47_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HAX1488246.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(1790..2446)
                     /locus_tag="JXV47_002229"
     CDS             complement(1790..2446)
                     /locus_tag="JXV47_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAX1488247.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            2816..4834
                     /locus_tag="JXV47_002230"
     CDS             2816..4834
                     /locus_tag="JXV47_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAX1488248.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     gene            5261..7675
                     /locus_tag="JXV47_002231"
     CDS             5261..7675
                     /locus_tag="JXV47_002231"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016183651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HAX1488249.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8023..9576
                     /locus_tag="JXV47_002232"
     CDS             8023..9576
                     /locus_tag="JXV47_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAX1488250.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(9957..11741)
                     /locus_tag="JXV47_002233"
     CDS             complement(9957..11741)
                     /locus_tag="JXV47_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1488251.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(11756..13477)
                     /locus_tag="JXV47_002234"
     CDS             complement(11756..13477)
                     /locus_tag="JXV47_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1488252.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13577..14338
                     /locus_tag="JXV47_002235"
     CDS             13577..14338
                     /locus_tag="JXV47_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAX1488253.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         4816 a         2728 c         2946 g         4321 t
ORIGIN      
        1 gagttattag cagaaaatgg attttatgcg gaactttatc ataatcaatt tgtatttgaa
       61 taaagaggtt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa tcaaaaacag
      121 cttctcatgt ttttgatttg gttggactta ttaccgcaga tataagcttt tgagcaccgt
      181 gaataaagag gttatgaaat caacgctcta acctgagtat tagagaaaaa aacgcaaaac
      241 atatcattta tgttttgcgt tttttattta tctttttttc tcaatacaat ataaaatagg
      301 cggctggttc ttttggttga taaaccgata attcagcaca ttatatgttt cctgtggcag
      361 tttggaacaa aaagaatcaa ccatatccag ttctttttct ccaccttcat gaccatagta
      421 gacgacaagg atcaatcgtc cgcgaggcac aagtcgtttc aatatttctt ccatagctgt
      481 gcgtgtagtc tctggcatag tgatgattgc tttatcactt tttgggagat accctagatt
      541 gaaaatccct gctttgagat tttgttgttc agctatcact tctcctaacg tttcgtggcc
      601 ttgtagaaac aatgagacac gttcttctaa ctgacgctgt tctagccttt cacgagtagc
      661 atcgattgct tgttgctgga tatcaaaact atagacatga ccagtttttc cgatgtgttc
      721 tgctagaaaa accgtatcgt ggccattgcc catcgttgca tctacgacgt gatcccctgg
      781 ttgcaagatt tcttgcagta atgtatggct gaaatgcaaa gcagtttgca acatcagacg
      841 ctcacctttt tccgtacatc atattttcct tggaagctat ctctgcgaag aagttcttca
      901 tcaattgcat tcaagacttc ccattttttc aagctccaca ttggtccaat caaggaatcc
      961 cacggcgcat cccctgtcaa acgatggatg atgatctctt ttggtatcat ttccagctgg
     1021 tcgcaaatga cattgacata gtcaggacgg ctcattaatt gaaggcgacc ttcatgatag
     1081 tcccgcaaca ttctcgtttt gcgcatcaga tgcatcaaat ggagcttgat tccttggata
     1141 tctgaatcta aaatggtgcg tctgacattt tctttcatca tttctaaact ttcgcctggt
     1201 aatccgttga tcaaatgcgt acaaacacgg atattatgtt tgcgtaattt agccacgcca
     1261 tctaaataag tttgataatc atgtgctcgg ttgatcagtt ttgaagtttc ttcaaaagtt
     1321 gtttgcaatc caagttctac ccataaatac atccgctcgt tcagttcagc aaggtaatca
     1381 actacttcat ctggcagaca atccggtcgt gtaccgactg ataatcctac gacacctggt
     1441 aaattgacta cttgctcaaa tcgttctttg attatttcaa ctggcgcatg ggtgtttgta
     1501 aaattttgga aataaacgat gtattgttgg acatgaggcc atttttgatg catcatgtcg
     1561 atttctttct ggaattggat tggaagaggg tcttcaggtg caacgatcat gtctcccgaa
     1621 ccagatacac tgcaaaaagt acaaccgcca tgggcaacag tcccatctcg attcggacag
     1681 tcaaatcctc catcgatcgg caccttgaaa attttcccgc caaactcatt tcgtaaagcg
     1741 taattccaag aatgatatct tttatttcct tctgaataag gaaaagtcat taaaagtcct
     1801 tctttctgta agagttatct atttgttttc ttttttctct atacactgga taagtcaggc
     1861 acagccaaga aagactgagt aagtagccgc cgatgatatc agtaggaaaa tgaacgccca
     1921 gataaatgcg gcttatcccg acacttacta taataaacat catcagcaat tgaagcaatg
     1981 tgcgtaaggt tcttttttga acaaaagctg gaagcagaaa tagtaaagaa ccgtaaagaa
     2041 tcatactgcc tgctgcatgt ccactaggga aactgtaact tgtttcaact actaagtgcg
     2101 ccaatgaagg acgctctcgc atgaaaaata gtttgatcac cgggttgatg attccagcaa
     2161 ttacaataaa tccagaaacg aaccaaaatg tttctgccct ttttttctta taccacatcc
     2221 ataaagccgc acaagcaaat aaaatgatga cggtaagagg attaccgaat ttagtcataa
     2281 agagttggta gctgttcaga tcaggataag aagctctgac aatgcctgta aaccactgat
     2341 cgaaaccaga aagccacgac agatggaact ttacgatcca gcccaaaatg aaaaacagga
     2401 caagaaagaa gctaccagcc acctgaaatg atgttttata tttcatacaa ttcctccttt
     2461 gaagcaatga cttattatag catttttggt ccagcgaaaa aaacggtaaa gagataaaac
     2521 caatgtatga ttcctctttg aataaccaat attcttataa aaaaaataac tgtaatcgga
     2581 aagacatttt ttggtaatgc aaatgaaatg ttagggaaat aaaatcagtg tttttcgaaa
     2641 tccttttaaa caagaacgta gacgtaggaa gaacttgaaa atgaacagaa gttgttcatt
     2701 acggtaaatt acaatatgat tacaaaaaac aacaaagctc ttaaataact tttaataaat
     2761 attaagagaa gttataatta ttaataatag ataaattgaa gttggaggat agaagatgga
     2821 aaacattgca agaaaagaac ggagacgttt agaacagacc aaacgttttc gaaaagcaaa
     2881 acgaggggca gcaatcgtgg gaactgcgat ggtaggctgt tctgtcgctg ccccattagt
     2941 acagccggtt cctgttcaag cggatgaaac acctgttcag ttcggcgcaa gaatcaatac
     3001 agcggcattt atcacagaaa ttgctactta tgctcaacca atcgctcaag ccaacgatct
     3061 atatgcatca gtgatgatcg cacaagcagt tgtagaaagc ggttggggca gtagtgcgtt
     3121 atctcaagca ccttattata atctttttgg gataaaaggc agctatcaag gacaaaccgt
     3181 ctacatggat acgcttgaat ttttaaataa tcaatgggta aataaaaagg agcctttccg
     3241 acaatatcct tcttttgctg aatctttcaa tgacaatgcc tatgtactta gaaatacttc
     3301 atttggcaac ggttattact atgccggtac ttggaagagc aacacgaaat cctatacaga
     3361 tgcgacagct tgtttgacag ggcgttatgc gactgatcct ggttacgcag gcaaattaaa
     3421 taatatcatc gcaacttacg gattgaccca atatgataca ccagctagcg gaaacgcagg
     3481 cggtggagcg actacaggtg gcaataatac tggaagtgca ggtagtactg gcggttcaag
     3541 caattctggt aatacaaact caggttcagc aacttcgacc acttatactg tccaatctgg
     3601 tgattctgtt tggggaatct caaataaatt cggtatcaca atggatcaat tgatccaatg
     3661 gaacaacatc caaaacaatt tcatttatcc aggacaaaaa ctgacaatca aaggtagcca
     3721 ggaaaatggc tcttcgacga ataattccgg taacaatacc aactcttcag gaaatgctgg
     3781 tacatcaaac ggaggacaaa caactggtgc gaaatacact gttcaatctg gtgattctgt
     3841 ttggaagatc tcaaatgatc acggaattac gatggctcaa ttgattgaat ggaacaatat
     3901 caagaacaat ttcgtttatc caggacaaca gctaatcgta tcaaatggcg gttcttctaa
     3961 tgctggagca aatactggct caaatactgg gaatacaagt ggctctagtt cgtccagctc
     4021 aagttcttct aatacagctt caggaacgaa atatacagtt aaagccggag actctgtttg
     4081 gagcgtctca aataaatacg gaattacgat ggctcagcta atccaatgga acaatatcca
     4141 aaataacttt atctacccag gacaacaact gactgtttca aacagtggat caacaaacag
     4201 cacgtcaggt aatacaggtt cgtcaaccaa tacaaataac agcagttcag ttaatactgg
     4261 cagcagttcg tctcaaggca cttataccgt gaaagcaggt gaatctgttt ggagcgtggc
     4321 aaataaaaac ggcatcacga tggatcagtt aatcgaatgg aataatatca aaaacaactt
     4381 catttatcca ggacagcaat tgatcgttaa aggtggaact tcggcaaata caaatacagg
     4441 ttcaactact tctgcagcga aaccaaatac accgaatacg tctgctacga caagtacatc
     4501 atccactggt aatacgatgt ataccgtgaa agcgggcgag tcagtttgga gcgtagcgaa
     4561 caaacatcat atcacgatgg atcagttaat cgaatggaat aatatcaaaa ataatttcat
     4621 ctatccagga cagcaagtga ttgtgaagaa aggttcatct caatcaacaa accaacaatc
     4681 agttactggt tcgaaaacct atactgtgaa atctggagaa tctgtttgga gtgttgctga
     4741 cagtcatgga attacaatgg ctcaactaat cgaatggaac aatattaaga acaactttat
     4801 ttatccaggt caaacgttga ttgtagctaa ataaaatagc tgttcgaaga aataacgatt
     4861 gaattccaca aaaatatttg ttactataag gctacttaaa tatgacaaca cttgaaaagg
     4921 aagtagtaaa aagactgaag tttcagagag cgcatggctg gtgagaatgt gcacggatgc
     4981 ttttgaactc gcctttgagt tgcccttgct gaatacccga gtaagcaagc ggcggtgacg
     5041 gccgttacaa cgttcgaggc cttttcacta aggtaaaatt aggtggtacc gcgtagatta
     5101 cgtcctataa aaagagcaat ctttttatag gattttttta tttcttttgt gaagtttgag
     5161 aaaacaaagc aaaaggaaat aaaaataaac agattctgcc ggttttttcg ttatatttat
     5221 aatagaaaca agtgttttca atagaacagg aggacagcaa atgagttaca atcataaaga
     5281 aattgagaaa aaatggcaaa aatactgggc aaaaacgaat actttcaaca cccatgatga
     5341 tcctgaaaag ccaaaatttt acgcactgga tatgtttccc tatccatccg gtcaagggct
     5401 acatgtaggg catcctgaag gttatacggc aacggatatc ctttcacgtg tgaaaagaag
     5461 tcaaggatac aacgtgctgc atccaatggg gtgggatgca ttcggtctgc ctgctgaaca
     5521 atatgcgcta gatacaggaa acgatccagc tgagtttacc caaaaaaata tcgaaacatt
     5581 ccgacgccaa atcaattctt taggatttag ttatgactgg aatcgcgaag tgaatacaac
     5641 tgatccggag tattataaat ggacacaatg gatctttacg aagctttatg aaaaaggtct
     5701 agcttatgaa gcagaagtag cggtaaactg ggtacctgaa ttaggaacag ttatttcaaa
     5761 tgaagaagtg atcgatggga aaagtgaacg tggtggctat gatgtagtca gaaaaccaat
     5821 gcgccaatgg atgctgaaaa tcactgctta tgctgatcgc ttattggatg atctagaatt
     5881 agttgattgg ccagaaagca ttaaagaaat gcaaagaaat tggatcggtc gttcagtagg
     5941 agcaaatatt gaatttaaag tggctggtac ggataaatcc tataccgtat ttacgacacg
     6001 accagatact ctattcggtg caacttactc ggttcttgca cctgaactag atcttgttag
     6061 agaaattacg acccctgaac aaaaagctgc tgtagaagct tatatcgaag agacagctaa
     6121 aaaatcagat ctaaagagaa cggatcttgc aaaagaaaaa acaggagtat ttactggtgc
     6181 ttatgcaatc aatccagtta atggcaagga aatcccaatc tggatcgccg attatgtatt
     6241 atcttcatac ggcacaggag ccatcatggc tgttccagca catgatgaac gtgactttga
     6301 attcgctcaa actttcggac tagaaattct tccagttatc gaaggtggag atgttgaaaa
     6361 agctgcttac acagaagatg gtacgcacat caactctgaa tttctagacg gcatgaacaa
     6421 acaagaagca atcgataaaa tgaatgaatg gctagaagaa aatggcgtag ggaaaaaaga
     6481 agtcagctat cgcttacgtg actggctatt ctcccgtcaa cgttactggg gtgaaccaat
     6541 cccaatcatc cattgggagg acggaacagt cacagctgtc ccagaagaag agctaccatt
     6601 acggttgcct aagacaaaaa acatcaagcc aagcggtact ggagaatctc cattagcaaa
     6661 tatcgaggag tgggtcaatg tcgttgatcc tgtaacaggt aaaaaaggcc gtcgcgaaac
     6721 gaatacaatg ccacaatggg caggaagctc atggtattac ctgcgttata tcgaccctca
     6781 taacaaaaaa gaactagcag attatgaaaa gttgaagcgt tggctaccag ttgacatcta
     6841 cattggtgga gcagaacatg cggtacttca tttactatat gcacgattct ggcataaatt
     6901 cttatacgat atcggtgttg ttcctacaaa agaaccattc caaaaactat acaatcaagg
     6961 aatgatctta ggcgaaaaca acgaaaaaat gtcaaaatct cgtggtaatg tagtcaatcc
     7021 tgatgatgtg gtcgaaactt acggtgcaga tacactgcgc atgtacgaaa tgttcatggg
     7081 gccattagat gcttcgattg cttggagcga aaatggctta gaaggaagcc gtaaattctt
     7141 ggatcgtgta tggcgtttga tcgttgatga gaacaataaa atgcgtgacc gtatcactac
     7201 attgaatgat ggcaagcttg ataaagtgta tcatcaaaca gtgaaaaaag tgacagaaga
     7261 ctatgaaaat cttcatttca atacagcaat ctcccaattg atggtcttta tcaatgaagc
     7321 ctataaagtg gacgctctgc cttatgaata tatcgaagga tttgttcaac tactcgcacc
     7381 gattgctcct cacatgggtg aagaactatg ggcaatcctt ggaaatgatg gtggtatttc
     7441 ttacgcacca tggccaacat acgatgaagc agcacttgtt gaagacgaag tagaagttgt
     7501 tttccaagta aacggtaaag ttcgtgcgaa aagcaatgtt ccccgagact taggaaaaga
     7561 tgagctagaa aaagcagcat tagccaatga aatagtgcaa gaatatattg aaggcaaaac
     7621 agtcagaaaa gttattgcgg taccaaacaa gttagtcaat atcgttgcta attaattggc
     7681 tctttgtcaa taaggactga tgagttgtgc aaaatcaaat ctgggccaga atgaacttca
     7741 ttctgtctca gattttttgt tatttcaaat tgattaattg attgatcaaa aaggttttga
     7801 ttttcatgtt ctcaaacacg ttcaatgtct ttttcttctg aatggtcttg taagagatct
     7861 ctgtaatcat caaatttttg tctattaatc ttagtatttt ttgatgtata aactacctga
     7921 aattgagagt acataccaaa ttcataaatt ttttattagt gggactagtg attgtatgga
     7981 ttttgacgca taatgaatga agtatgagaa aaggagagac aaatggatca agaactattt
     8041 attatcgaag tattatcagc taaacaaaaa attatcgaga aagcgaaaaa aagagcgaaa
     8101 agaataatgt tcaagctttt aagcttagta tttttctctg gtttgctttt tttcggagct
     8161 gtatcgttcc tatatcgcca tatgagtgca gtagtccgtt cagctgaagg gatgcaaaaa
     8221 ttaaataatt tgtatcactt ttcgtgggga gttggcggaa taacaattgt tgtgcttatt
     8281 gtttttcttc tacttatttg gctccgttac catcaattgt cgcgtcattt cgatcaatgg
     8341 cttagtcaaa gagcacaaca gtttttacat aataaaccaa cttctcaaga tgatgactat
     8401 ctttattttg agaagacttc gacgagtcaa gcttttcgga tacaaaaaag tgattgccag
     8461 ttattgctga gatcacttga tgatttacct atctacttag gcgaaagcaa atcaaaattc
     8521 ggaatgaaca cattccatat ttttttacta gaaaacgaac ccagatggga aaaaagccag
     8581 tcttcgcctg gtggatacct gacaactaag atgagtacat tagtcactgg ttttttcctc
     8641 attcttttag ctggaacaat ctattatggg agatacactc agccaaaaat gtcttctcat
     8701 ataaatgctg cttctcacat gacaatgaac tcaactaacg atacgcatat acaaaagaca
     8761 aatgaagggt tgttagctga tcctaagcaa aaggtaaatt tgacaacaca aaagataaat
     8821 gatctcaaac ttgatacaga gacgcactct ctctatatga caacagatag tggtgctaat
     8881 tgggtatttg tgccgattga ttcgcaatgg ttgcgttttg gcgaatacac cctgacaacg
     8941 gggctgattc ctgaaggtta ttggatggac aacacatatg atatttccgc cgatttctca
     9001 tggtttatct attcttctgg ggatgatgta cgtctgctga cttcaagaga taatggtaaa
     9061 acatggcaaa cgtctattat cacccaatca gttcagccga tacgttatcg aaaagcggta
     9121 ttttatggca acgatggtct atttatctgt acatcagcca gtgggatgtc tgcagaaact
     9181 ttgtacattt acactactat ggatggcgga atcacttgga taaaaagtgg aagtacaatg
     9241 atcaatcagc cagtacaaaa tgtcagcttc gttacaactt ctttaggttt tgtttcgaca
     9301 cgtgaaagtt tgttttatac aaacaacgga ggacgctcat tcaaagaatc agttctgtcg
     9361 attccggaaa actatcagac aggggggata gatctttttc aatcaccaaa tgaagttact
     9421 caaataagcg cgaatacgtt agagacaaaa ttttatttgt tgaaaaaagg accaatcgat
     9481 gcagggaaaa tgtttgcctg cctcttccgt tcaactgata acggggaaac atggcaattc
     9541 gttcagcaac tatcgcaagt agaacaagga gattaaagaa gagagattgt gagcctgacg
     9601 ttcagcaccg agtcacaaga aacaaattca aaaaacagct tctcatattt gttgaatagt
     9661 gtaactcgtg attcggagtt gacaagagca acaagaagcg attttgaagt atagcttctc
     9721 gtattttaca agatcgtgtc ttattgccga taggttgtct cttgaacacc gtttattcgt
     9781 aaaaagggat tgtgacaagt cttttgtcac tacttaccga acgaaactga aggagctatc
     9841 caaaaagtat cattagtatt attctttgtg tttctagtgg caccactagt acatttaaaa
     9901 aagctatcga tcatggacta atcatacatg atcgatagct ttttagataa tgtttgttac
     9961 gctatctgaa attgactatt ataaagactg gcataaagcg ttggtgattg gagtagttca
    10021 gaatgtgttc ctttttcgac gatatcgcca ttcttcatta caaggatcat gtctgcattt
    10081 tcaatcgttg acaaacggtg tgcaatcaca aaacttgtcc tatcttttgt cacagcttcc
    10141 attgcttgct gaatcaatgc ttctgttcgt gtatctacgc tagaagttgc ttcatctaaa
    10201 ataacgacag gaggattcgc tagaatgact cgagcaattg tcaataattg ttgctgtcct
    10261 tgagataacg tgccgttttc gctagaaatg atcgtatcat atccgtctgg cagtgttcga
    10321 ataaagtgat cacattgtgc gatttcagcc gcttcgataa tttgttctct tgtggcatcc
    10381 attttcccgt aggcgatatt atcagctacc gttccttcaa acagccaggt attttgtaaa
    10441 accatcccaa aagaacgacg tagttctcca cgtgaaagct tggtaatatc aagaccgtcg
    10501 aattcgatct ttcctttatt cagttcataa aaacgcatca gcagattgac taaagtcgtt
    10561 tttcctgcac cagttggacc aacgatcgct accgtttgtt ttggctttac tgaaaaatcg
    10621 acttgattca tcaatatttt atctgatgtg taaccaaact gtacattttt gaaagctatt
    10681 tttcctttcg gttgttctaa aagtcttgca tctggaaggt ctggaatttc atctgtttca
    10741 tctaatatct caaatatcct atcgattgct gccattgcgg attggatcga gttgatcaca
    10801 taagaagcgg tagaaattgg ttcagaaatc tgattgatgt actgaagata agcttgtaag
    10861 aagccgatcg tcacaccacc tgatagaaca agcatagcac cgaataccgc acttatgatg
    10921 aaggcgagtt gattaatgaa acgaatggcc ggatagatag cacagttcat aaattgagca
    10981 cgtttaaaag cgttgtattg ctttttattt acttcgtgta tagcagcttc tgcatgagct
    11041 tgctgattga atgttttgac cactagatta ccagctaaga tttcttccat tcgattattt
    11101 aaaacaccca gttcatactg attctgttca gaaatctgtt tgtttttgtt cgcaatctta
    11161 gttgtaacaa ttgaactgcc aacgatcagc aataagacga gcaaagtaag cttgctttcg
    11221 atataaaaca gcatcagacc agcagcagct attgttacga cagaagtaaa aaattgattg
    11281 atacctgtca ataacacttg agaaagttga ttgagaccgg tagttgtccg actaatgatg
    11341 tcacctactt gatgattgtc aaaaaacgac atcggtaatg ttttgaattt ttttgtgatt
    11401 tcttttcgca ccctcaatgt gatcttttcg cttaacgctg ccattgtccg ttcctgaata
    11461 aatgaagtga tgctgcttaa gactgaacag ccgatcagca ataagacagg gaacaacaat
    11521 gcttgtttga tatcactgaa agaaagctgt ccaatacctg tttttcttat ttctgataag
    11581 agatcatcga tcccgattcc catgatcaag ggcatggcta cgactaatag gttcccgaat
    11641 aaactgcata gaaacaatcc gtaaaaatat ttatgttcag gtttgatcat tttccaaaaa
    11701 cgtatcaaag cacgcgtgtt caacgttttt ttcttttcca tcgtatccct tctttctata
    11761 ttccttgtga ttttgcaaac tcctgataag tttggcaatt agacagtagt tcttcatgag
    11821 taccttgtcc aacgattttt ccttcatcta aaacaatgat gttatctgct tgttggattg
    11881 tactgaggcg ttgagcaaca atcacgagag ttttctccga catgtgttta tgaagggctg
    11941 ctcttaatgc tgcatctgtt ttatagtcta aagcggagaa actatcatcg aatacataga
    12001 tctctgctgg tttgatcaac gctcgagcaa tacatatccg ctgtttctgg ccccctgaat
    12061 aattagaacc gccttgagca acaaagctgt ccaatccgtc aggaagggtg tccactagtt
    12121 cttctaattg agcgatcttg atcgctttag acaactcttc tgttgaggca tattcatttc
    12181 ccatctgcaa gttgcttaaa attgtcccgc tgaataagaa agccttctga gggacataac
    12241 tgatgtggga gcggatctgt tcttgagtca tttgagtaag aggaatacca ccaagggtta
    12301 cttttcctat cgtagggtca ctaagtctca agagaagttt cgccaaacta ctttttccag
    12361 atccggtccc gccaacgatc gctgttgttt ttcctttagg tattgtgaaa tcaatatctt
    12421 ctagaactgg atcagagatt tcagtatatt taaatgtgac atgttcaaaa gcagctgcat
    12481 ttgtctgatc aaaggttggt tcagctactg ttttgatcgt ctcttcctca atttcgatct
    12541 ctgcttgcag tatttcttct atccgtcgta atgaggcaaa cgatttaggg ataatgacca
    12601 ataccatagc tgcgatcatc aagtaagcaa gtgtcagcat agagtattcg actacagcag
    12661 tcacgacacc gatttgtaat gctccttctg ctacaagatt tccgccaaac cacaaaatag
    12721 aagcataaac gattcccatg agcaaaaaag caattggagt gacccaagca aatattcggt
    12781 tcactttgat catttgatta gcatagtcag caaagctctt attcgttcgc ttttcttcat
    12841 atgattgatt atcaaaggca cggatcatat taatcccagt aaagaattct ctcaatgtga
    12901 tggtgatccg atccattttt ggctggatac tcaaagataa aggtgcccct cgtttcatca
    12961 gtcgataaac aatccataca taaaaaacaa cagagatcaa tgtaacccat gttagtaata
    13021 gagaataacg aaacatcatg agaatggtga aaacgcaaat aaccggtgct ggtaagatca
    13081 tttggcaaaa taaaacaatc atttgctgga cattatcgac atcattcgtc attcttgtca
    13141 aaagagatcc agaactaaaa cgactgatat ccttcattga cagctgttgg aatttacgga
    13201 aatatttctc ccgcgtttgg aatccaaacc tagcggaagc caatgctgaa aagtaactag
    13261 aggcaactgc agcgattgtt cctagaaacg ctacaagcag catttcaact ccaatttttt
    13321 ttataactga ggcttcgcca cttgctatac ctgtgtcgat cagctttgct actaattttg
    13381 gtacacctaa tgtaccggcg atttctaaac agatcatcac aaaggtaagg agagcgagtc
    13441 ctttgttttt ctgtaagaat gtttttaaga tagacatatt attcctcctt ttttcctgat
    13501 acttttcgat tctatacctt caagtaactt gaaggtcaat agaaaaaaga ataaactgaa
    13561 aaagaggtga gaaaaaatga aaaaaatgta tacgattggc caagtatcgg aactatttga
    13621 tttgccaaaa tcaacgatcc gctattggga tgaacaagga ttaatccgtt caagtagaca
    13681 agaagagaat gattatcgat tgtttgatat cgatgatatt tttatgcttt atgatatcgt
    13741 tttttataga aaattagata taccgatcaa acagatgaag aatttatatg gaaaaacatt
    13801 gacggagtta tatgagacac ttgatgaaac agaaagaaga atccataaag aactggtggt
    13861 gatgaaacaa aaacaaaaag agataaggga gcaaaaaaaa cagttgaaat tgatgatcga
    13921 tacaaacgag gaagaatttc ctgtagaaga gatccctttt gactgtatga tctcaacgga
    13981 gtttgaagat attgtggaaa tcaaaaaatt tctacctaac tattcaagct ttgggatgat
    14041 gagtatgcca gcttccagtt cacagacgat gtatggattt tttatcgacc ctagtgaagt
    14101 acatttattt actcaagacg tgatttggga gaaaaaagat acggctgttt atcgtcgatt
    14161 cttattgaaa tccgagatga accatgcgga acgtaataat attttagaaa tcagagaaag
    14221 aatgtatgaa aaaggatgga aaacaggaga agtgatcggc cagtatctat tgacgaatac
    14281 ggatgaaaac aatatcagaa ctgaatatta tcatgcatgg atagaaatga aaaaatagga
    14341 aatatgtgtt taagataact cgaaaatgat ggttgtttta gttataaaga aaaattttct
    14401 ggttcgatta cgggtttaat gtgggggatt attagtcgtg gatagataga attttagttt
    14461 tttagaggaa atatgtcttt aaaaatggaa tggttgcaat tcttagcgat atatacgatg
    14521 taattgtcct cttaaaaaag tatggaaaaa taattgtatt gggtgttatg tataattcat
    14581 ggtgaactga gactaatgag aagaaaaatt catattgtta tgagtgagat tgtatcagat
    14641 gagaatgata aattaaatag gtgcataaaa gcattacact taaaatacat tgttgcttac
    14701 attattacaa tatgttaata aggcaaaaat aaatagatgg attgaataaa catatttttt
    14761 aatcaaatag tccctactgt gactttcctc agctatcggt gatactaccg a
//
LOCUS       DADGKS010000068        14575 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.069, whole genome shotgun sequence.
ACCESSION   DADGKS010000068 DADGKS010000000
VERSION     DADGKS010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14575
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.069"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            17..1357
                     /locus_tag="JXV47_002236"
     CDS             17..1357
                     /locus_tag="JXV47_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAX1488254.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            1575..2018
                     /locus_tag="JXV47_002237"
     CDS             1575..2018
                     /locus_tag="JXV47_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HAX1488255.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(2522..3940)
                     /gene="nhaC"
                     /locus_tag="JXV47_002238"
     CDS             complement(2522..3940)
                     /gene="nhaC"
                     /locus_tag="JXV47_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAX1488256.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(4343..5566)
                     /locus_tag="JXV47_002239"
     CDS             complement(4343..5566)
                     /locus_tag="JXV47_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HAX1488257.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(5597..6436)
                     /locus_tag="JXV47_002240"
     CDS             complement(5597..6436)
                     /locus_tag="JXV47_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HAX1488258.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(6453..7133)
                     /locus_tag="JXV47_002241"
     CDS             complement(6453..7133)
                     /locus_tag="JXV47_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1488259.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(7135..8208)
                     /locus_tag="JXV47_002242"
     CDS             complement(7135..8208)
                     /locus_tag="JXV47_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAX1488260.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     gene            complement(8855..9526)
                     /locus_tag="JXV47_002243"
     CDS             complement(8855..9526)
                     /locus_tag="JXV47_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAX1488261.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(9613..12291)
                     /gene="mgtA"
                     /locus_tag="JXV47_002244"
     CDS             complement(9613..12291)
                     /gene="mgtA"
                     /locus_tag="JXV47_002244"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HAX1488262.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            12950..13387
                     /gene="ndk"
                     /locus_tag="JXV47_002245"
     CDS             12950..13387
                     /gene="ndk"
                     /locus_tag="JXV47_002245"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HAX1488263.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(13409..14275)
                     /locus_tag="JXV47_002246"
     CDS             complement(13409..14275)
                     /locus_tag="JXV47_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAX1488264.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
BASE COUNT         4174 a         3037 c         2576 g         4788 t
ORIGIN      
        1 aagaaagagg tcatttatgg aagataaaaa attgaaaaaa caacttagct ccagacatat
       61 caccatgtta gctttaggtg gagcaatcgg tgcaggtcta tttaaaggaa gtggcgaagc
      121 gattgggatc gccggccctt ctgtattgat tgcttttttg attggtgggc tgattttata
      181 tatcgtgatg aaaggtctgg gaaaaatcgt tttaagcggt ggcgacacgc atcacggatt
      241 atctggtttg atacgccctt atctaggtgc tcattctgct gattttactg attgggtcta
      301 ctggtctatg tggattatca atatcatcgc tgaagctgtt gcagctgctt cctttttgca
      361 gttgtggttc ccgcacattc cagcctgggt atttgttttt atgttggctg ttttaactac
      421 gatcatcaat ctttattcgg tacggttatt cgcagaaaca gaatattggc tggcttttgc
      481 taaaatcagt gtcattatct tactgatcat ttttgctact tatcttgtcg gtcagcaaat
      541 gttgggcaca ggcgttttcc ctacccttca gcaattgact gaccatggtg ggtttactcc
      601 tcatggtatg aagggaatca tcagttcttt gcttgtagtt atctattctt acggcggttc
      661 tgaactgatt gctatcacgg taagcgaagc agatgatcct aaacgtgcga ttcctaaagc
      721 aatcaaaggt gtcatgggaa gaatcatttc cttttacatc attcctttgt ttttgctttt
      781 gattcttttt ccttggaata ctttagcagg cacgaatgtc agtccttttg tgatggtatt
      841 tgaaaaaatg aatatcccat ttgcagcgga tatcgtcaat tttgtgattg tccttgcttt
      901 gttctcatct atcaattcgg gtgtgtatgc atcttcaaga attttgttct tccgtttgaa
      961 ggatcgaaaa ggttcctcta gaaaactagc tgttttaaac aagcatcaag taccgcaacg
     1021 tgctgtttta ttttgtacca gtgttcttta tcttggtgta gctctttctt attttgtcgg
     1081 tgacaaatta tttggctatc tggcaggttc cctttcgtat acagtattat tgatctggat
     1141 cattatcagt gcggcatcct ttgtactggc actaagaaaa ggaacattat gggataaagg
     1201 aatcagcttt tttgcattag ctgtcttagg attgattttc cttggtatcc tgttcacgaa
     1261 ctccattggg gtaactgtat tgactggcct gctttacctg ttcatttatt tcagttatca
     1321 aaaaaagaat gatgcgttcg tattgacgaa tgaatgaaat cgatagaaaa ttttatttta
     1381 tttatgtgga atagatggag ctattgaaga aaggagttgt gacaaaagtc ttgttgcaac
     1441 tcctttttcc gaataaacag tctcatgacc tcttggtaaa cggtgttcaa aaaccctctg
     1501 tgcaaaataa ttgattgttc tccatgctca tgacatgata gaagaaagga atgaaaaaaa
     1561 ggagtttgtt ttaaatgaaa aagtattgga agtttttgtt gatgatcggt gtttcaacgg
     1621 tagttatgtt tggtatgatg tacttgaatg tctatgcgct cgatcatatc ttcttcagtc
     1681 gtacacgagt attcatggcg ttgatgatgg gtgcagtcat ggcagtcatc atgctgttgt
     1741 tcatgtggaa aatgtatgaa aacaaaaaga taaatgttat gatcttagcc gctagtcttc
     1801 ttgtttttgc cggttccttg tttatggtac gaagccaaac tactgtcaac gacacagctt
     1861 ggatgaaggc catgattcct catcattcta tcgctatcct ggcaagtaaa cgagctgatt
     1921 taaaagatcc tgaagtaaaa aaattagcgg aagaaatcat tcaggcacaa gaagaagaga
     1981 tcgacaaaat gaaaaaaatg atcaaagaaa tggaatgacc attatccgtc caaataaaaa
     2041 aagaggatgt tccagaagtt atcagcttca agaaataaga agaagctact tctggaacgc
     2101 cgtgaataag gggttgtgaa aaagctgccc tgcatcaagt aataagaaca gccaaacaaa
     2161 aatagcttct cctatttttc gtttggttag gcttattacc gcagatgcaa gcttttgaac
     2221 accgtttatt aagaggttgt aaaatcagcg ttctgacctg agtattagag agacaaatgg
     2281 aaaaatagtt cctcatattt tgccattttt tgagctaata ccgagggtca gctgattgaa
     2341 caccgtttat cgagaggttg tgaaaaagtc gcttagtttc gcgtattaag aaaaattttg
     2401 tgaaatggct ttccacattt ttgtataaat ttggcttaat accgagaaac tggcttttga
     2461 ataccgttta ttcgtaaaag ggattgtgac aaaagtcttg tcacaatccc tttttatgtt
     2521 tttattgttc taattgcgct gtcttgctta ctgcttcttg cggtttcaca aatttttttg
     2581 agattcccca acctgtgaag gcactgacca tcgaaaacac aggagaaagc aaactgaaaa
     2641 atacgaatgg caagtaagtg agtgtaggaa taccaaatgt acttgctacg aaacttccgg
     2701 caattcccca aggcactaag tagttgatta ctgttccacc atcttctagc gttctaccta
     2761 atacagttgg atcaaatcct gctttttcat aagtttcttt aaatgcatta ccaggcagaa
     2821 taacagatag gaattgttca ccaataaaaa tatttactcc gatacttgtc atcaatgttg
     2881 taaaaatcaa atttggtgtg ttcgtcatct ttcttgatac tcgttccatc acggttgaga
     2941 tcaagccaaa ttcgatcaac aatccaccta atgacaaagt tagaataatc aatgacacag
     3001 taggcatcat actttcgatt cctccgcggc taagcagtga atcgatttgt tggtttccag
     3061 tatttgaaac aaaccctgat tcgatgaccc cagccaactt cgttaaggaa gtttgtgggt
     3121 tttgaataaa aatcattcct actgctacag cgatattcaa caaaatcgtt aaaattgccg
     3181 gcaccttttt ccatgcacac agtaacatta aaaataaagg aatcagtgac cagattgaaa
     3241 tagtaaagtt tgcttctaga acatcagtca cttcacgaat agatgaaaga cttgcggctt
     3301 tacttgtgtg tcctaaaatc atgaataaaa agaaagaaac aacaaatgcc gggacagttg
     3361 accacatcat atgcttgatg tgtttgaaca aatcggcatc aacaatagct gctgctagat
     3421 ttgttgattc ggataatgga gacatcttat ctccaaaaac ggcacctgaa acaatagctc
     3481 caacaaccag cgctggattt aagcctagtg ttgtcccaat accgaaaaat gcaatcccaa
     3541 tcgttgacat aacagtaaag gcactcccta cagcgctacc tacgattgca cacacaacaa
     3601 atacagaagg gacaaaccac tggacactga tcaatttgaa cccaatgacc attagagttg
     3661 gaatgatccc tgcttgtatc catacagcaa tcaatgaacc gactaaaata aaaataaaga
     3721 ttgggatgat tcctggtttg atgccattga tgattccttc gtgcagccaa tctgtcgggt
     3781 atctttttat cactgcatac aacatgacca ttccgatcgc tgctaagatc gtgatattag
     3841 gtgagacctt taatccgaca acgccaatcg caatgcctaa aacaataacc attaatacaa
     3901 gtgttgcttc taaaaaactt ggtgttcctt tttttcccat gataatctct ccttttttag
     3961 ttgttcttat gttctaaaaa agttaagata tcggattact ccgccgcaat tcatccgcga
     4021 ttcctccttt ataaaaataa aaagacctgt tttaaactaa ggacgaatga ctccgcggta
     4081 ccaccttaat taaaaacaga tctgtttttc actttcaaac ttttattcaa atgtatggac
     4141 tttccatgta attcgtcaat taggcttgat cggttcacag cgaccaccga ctttctgaac
     4201 aaaacaccta accgctactg cgtgaaaagt tgacttgtac gaagtttacc ttccataaga
     4261 tcatttgtca atgaaaaaga aaatattttt tcatttttct gaaaattatt tttataactt
     4321 tcacacacaa gattattttt tactagaaag tagcgccctc ttgttttttt cttgctacta
     4381 tttcttgatg ttcttgcttg attctttcta atagctttgg ctctttcaac agatcaagag
     4441 ctgtattggc gagtagttct gctgcaatcg caatagaagc aaggcctttg tcacttttag
     4501 cagcagcttt gaattcttct gtgtgtccgg caatatatgt ctcagagatt gctaccgtag
     4561 gctggattgt tggtatgact tggctgacat ttcctacatc agaagaaccg agacttgttc
     4621 tttgttccgt ttctatttct tcatctggaa cacctgcttc ttttgcatgc tggaagaata
     4681 agtcatcaaa agaaggagta acgatgacat catcaactgc attttggaac aatccaaact
     4741 caaaagtcgt gcccgtactt atcgcagcac ctcgtacgat attttccact ttttcatata
     4801 ctttatctaa tgtttgccga tttcctgcac gtaaatagaa acgtccagca gcgtaatctg
     4861 gaatgacgtt ggcagctact cctccgtctg taatgatccc atggatattg acatcttttg
     4921 gcaattgcaa gcgtagagcg ttgattccat taaacacttg gatcaatgct tccaaagcat
     4981 ttactccttt ttcaggtgct gctgctgcat gggaagcgac accgtaaaat ttgatgtcga
     5041 ctggatcatt cgctaaagat tctgtcgttt tcccataacg aaaagctgga tggacgcata
     5101 acgctacatc gacatcctca aaaaaacctt ctcgaacaaa gctgccttta gctgatccgt
     5161 tctcgccccc ttcttcccct ggggtgccat atacacggat ttctccacca gtttcatcaa
     5221 tgaattgctt cactatgctg gcggctaata cggagtaagt accaaacaaa ttatgcccgc
     5281 atgcatgacc aatacctggt aaagcatcga attctgccaa aaaggcaatt gtgggaccgg
     5341 gtttattgga aatataacgt gcatcaaagg ctgttcggtg tccagctact tctttttcta
     5401 cccaaaacct ttctttttct aattgtttaa tcaacgctgc tgaggaataa aactcatagt
     5461 tacttacttc aggatgttcg tggatatcta gagcaagtgc ttgatattct ggtaaacgat
     5521 attggattag atccttcaat tggtttgttg agattgttgt tgtcataaaa aattcctcct
     5581 atgctagtca tttttcttat tttctcccga atgtttccca tgcaggcacg cttgatcctt
     5641 ttgatgtttt ctcgattact ttgactgtgt cttctgtttg ataagcgtct actatttttt
     5701 gatacgtttt attgttttca tcttcttttc ttgcaacgat gatattcaca taaggacgtg
     5761 catggtcatc cactggttct aagaagatgg catcagaagc aggattaaat ccagcatcta
     5821 cagctacacc gctattgatc actgaaatgt ctacatctga caaagcacgt gctgtttggg
     5881 aagcatctaa ttcagaaatg tctagatttt ttctattctc ggtaatatca gaaacagtgg
     5941 gcgcttgtcc ttttgcctta tccactttga tcaatccagc agtttgcaat aacagaagag
     6001 ctctgccgcc atttgtaaca tcattaggga ttgctacttt tgctccgtct ttgatatcag
     6061 ctacatcctt caaagtgtta gaataaattc ccagcggtgc attgacagta tttccgatcg
     6121 atactaaatc agttccgtgt tctttattgt aattgtctaa aaagaattga tgttggaaag
     6181 aattcaaatc aatcgatcca tctgctaaag ccacatttgg ttgattgtaa tctgtaaatt
     6241 tcacgtattc caaattaatg ttctcctttt tcaaacggtc tttcacgttg tcccatacat
     6301 ctgtatcttc tccaataatc cctagtttta cgatagtttc ttttttgtca gttgtatctg
     6361 cttttccttg gctacaccct gccaaccaaa taattgctac aaatgtaatg actacaaaac
     6421 gaataatttt tttcattttt tctcctccac tttcaatgtg taattttttt aatcagttga
     6481 ttactgataa attgacttaa aaaaactaag attagaatca ataatgtagc cacaatcgtt
     6541 acatctgttt ggaatcgatt ataccctctc gatatagcaa gattccctaa tccgcctgca
     6601 cctactgctc cagccatggt agtcagtccg atcacgttga tgatagtcaa cgccgagacc
     6661 cgaatgatac caggcaaacc ttctaacaaa tacacacgta aaatgatacc gattggactg
     6721 gttcccatcg cttctgccgc ttcgatcacc ccaggatcaa cttctagcag tgcgttctcg
     6781 atttgacgag caaaaaacgg aacaactcca aaaatcaatg gcactaaagc tgctttcgca
     6841 ccaatcgtcg ttccaactaa gaaacgagta gtcaatgcta aaagagaaag caagataatg
     6901 aaagggatgg aacgaatgat attgatcagc ttatcaagta tttcaaatag cagacggtta
     6961 gctagtaatc cattagggcg tgtcactact aacgtcacac ctaagatgat tccaatcatc
     7021 ccgccaatga atgctgtcca aaaagacata tatagtgttt gcttcgtcgc ttcgacaaat
     7081 tcatccggaa tcaaataaac attgggcaaa tatgttttaa agaaatcagt cattttatct
     7141 tcctccttcg atcactttga tacgactatc taaatcgttt ttttgtaaaa tatttatttt
     7201 tacaccagat ttgatcaaat aatccaatgc ttttttccgc tgtttggttt ctccagctaa
     7261 agtaacgatc aaactcccta acggcgtttc ttgtaataac tctacattgc catataaaat
     7321 attcgctgtt acttgatatt tgctgtacag atgagcgatt agaggttcgt tcgtctgatt
     7381 tccaatataa cttaattcca ccagccattt attggcgatc tgatcggcaa aagcagaatg
     7441 ggcaatgatc gtttctaatg cttggtcaag atgagtagct gttcgaataa aatctttggt
     7501 caattcttct tcaggattgc tgaagatctg gatgctgcta cctttttcaa cgattcttcc
     7561 atcttccata accgctacct tgttgcagat ttctttgaca acttgcatct catgagtgat
     7621 caggacgatt gttaaaccta actggcgatt caattttttt aacaatgcaa ggatctgaag
     7681 ggtcgttttc ggatcaagtg cactggttgc ttcatcacat aataatacct taggttcatt
     7741 cgccaaagct cgtgcgattg ctactcgttg tttttgtccc cccgacagtt gtttaggata
     7801 agcagatgct ttttcttcca aaccgacaag ttccagtagt tcattcactt tttgacgacg
     7861 ttcctgtttc gattttccag aatactttaa agaaaaatca acgttgtcaa aaatagttcg
     7921 gctttccatt agattgaaat gctgaaagat cataccgatg gcctttcttt cttttcgcaa
     7981 ttctttggga gagagctgac tcagattcgt ctgattgaca atgacttctc ctgctgttgg
     8041 tttctgcagc aaattcatca cacgaactaa cgtacttttc cctgcacctg agtaaccgac
     8101 gattccataa acatcgcctt tttcaatcgt taaatctaca gaatctactg cctgtatctc
     8161 tttttctttt tgtttgaaac atacagaaac atctcgcaat tcaatcatta aaattcctcc
     8221 ttatctaaaa aaagcgtcct caagaaaatg aaaatgtcat tttcttgagg acgctttttt
     8281 gcgtgttacc acctcatgtt caagctgtgt tcacacacaa ctcctcttca agtacgatca
     8341 tactctagca agatatcggt cgcagccgtc atcgccttac atctatgctc gggatgaatt
     8401 gctcgatggc cattttccaa tagtcgttcc ttgcttcttc tcagctaccg aagctctctg
     8461 tcaaaggttc ttctatcgta cttaccattt caatgcaaat aatattcaaa aaaaaagtcc
     8521 ttttactaac ataaactatg tcagtaaaag gacgacgtat cgcggtacca ccttttttcg
     8581 gaagtttcct tccctcaagc ccaacatctc aaaaagagag attggcgttc gttttaacgg
     8641 tcgaacagtt ccgaatttgc ctacttatcg acaaattatt ctccaaggcc attttcagct
     8701 tttcttactt gactcttctc accagccaga gcctctctgc aaagtttcca aacttacttt
     8761 ccttttcaac gaaatcgata ttttgttgtt gggattaatc tacatgagga aaactgaaaa
     8821 gtcaagtacg aaattcaaat tattttttct atatttattt ttctgttttt ttatttaaca
     8881 tttcaataac agttcgaaga tcttttcctt ccgcaagaag tttcaatttt tccttttctt
     8941 cgacggtata atttcggaca aaactggaat caggtatcaa aacaacgcct aatcctgctc
     9001 gtgaagcagc tgttgctcct actaaagaat cttccactgc aaaggctgaa ctagcttcta
     9061 atcctgttcg ttccaaagct gtcagataag gaatcggtga aggcttgttc tccgacactt
     9121 cgtctccgaa tgtaaacgtg tccaagtaat cagctaattt aaagtgatcc aagatatctg
     9181 ttgctctttt cgtaacagtg gtcgtagcaa tgcctagttt catatgacgt tcttttaagt
     9241 ctgccaatat ttcttttgca tatggtttta agtggatggc tccgcttgtc agctgttgat
     9301 aaaaatattc ttcacgcttc gctcggactt cctgtacttt ttcagggcta cctgctgctt
     9361 tcactaaaat atcaaaactt tgtttccagt tttttccgcc ccaagcgtca acgatttctt
     9421 ttgggatatg gatatcaaat tgctgaaatc cccaaagcca gccatcacga tacgtttttt
     9481 ctgtgtcaac taacaaacca tctaaatcaa atattgcacc tttcatctat acattaatcc
     9541 tttccaaaac aatacacata gtttagcacg actggtccaa aaagaacaga agcaaagaac
     9601 cagccttctc gtttataaga gttcttggaa tcgacggata tagattttct tcacagctgt
     9661 cacaagcgcc agataagcga tgactgtagc aaataaccat aaccagtaat tgccaggaag
     9721 tggcatcaag cctaattcag caccaaaact tgtaaaagga aggacagaac cgacaataat
     9781 tcctaatgta gtgataacaa acatggcaaa tgttgcgttg ctttggataa atggtacttt
     9841 cggtgtacgc agtgcatgga gcactaaggt ttgtgtccat agtgattcga caaaccatcc
     9901 tgcatggaat aatgcgatga aaatcactcg ctgtgaacta tccaatgtat ggaaacttcc
     9961 gcccactaca gcaggacaaa taacaaaata catcaacaag taagtagtaa tatcaaatat
    10021 cgaacttgtt ggaccaaagt aaaccatgaa ttccccaata ctagatgcat tccatttttt
    10081 tggctcgtcc aaatattctt tatccatccg atcccatggc aaggaaatgc aggaaacatc
    10141 atagatcaga ttcaaaaaca aaagttgtaa aggcagcatt ggtaaaaatg gcaggaacgt
    10201 acttgcaatc agcacggaaa acatattgcc aaaattagaa cttgctgtag ccttgatata
    10261 tttcatgata ttcccaaaag tttctcgtcc agaaagaagg cctctttcca aaatcgtcaa
    10321 atctttttct aaaaggatca cgtctgcaga ttctttcgca atatccacag ctgtatctac
    10381 agaaataccg atatcagcca ctttcattgc aggagcgtca ttgataccat ctcctaaaaa
    10441 tccgacagta tgaccatttt tacgtaaagc tgtcgtcaaa cgtgcttttt gctgaggatt
    10501 caattttacg aatacttcat ggtcttcagc tacttgtgct aattcatgat cactcatttc
    10561 cgagattttc tcaccggtaa ccaattcatt gatctctaga cctacttgac ggcacactga
    10621 acgtgtaact aattcgttgt ccccagtcag aacttttaca gctacaccat gttctttcag
    10681 agctttcaac gcttgtttcg ttgtttcttt tggtggatca aggaaagcaa gataaccaat
    10741 caaaaccatg tctgactcat ctttgactga aaattctcca acgacgcttg gattggtctt
    10801 ttgtgcgaca ccaatcactc gtaagccatc ttcattaagt gactgtactt ttgcaagtac
    10861 ggcttctttt cgttcttttg ttaatggtgt aacagtaccg ccaagatcaa taaatttaga
    10921 aatgttcagc atttcttcaa tcgcaccttt tgtgatcatt tgtgttttac cagctggatc
    10981 agcaaccaca acactcatac gacgacgttc aaaatcaaaa ggaatttcat ccactttttg
    11041 ataattgatc ttatctgtat ctaaagtttc tgttgcttca tcaatgatag ccacatctaa
    11101 caaatttttc agccctgttt gatagtagct atttagatac gcatggcgca aaacacgatc
    11161 atcttcattt ccttcacaat ccatatgata ttcaagaatg attttatctt gtgtcaatgt
    11221 ccccgtttta tccgtacata acacatcgat tgcaccaaag ttctggatgg cattcaaatt
    11281 tttgatcact gttccttttt tggccatcac acttgctcct ttgaccaaat tcgtcgtaac
    11341 gatcattgga agcatttcag gtgttagacc aactgctaca gatagtccaa aaagaaaagc
    11401 ttctagccaa tccccttttg taagcccatt gatgacgata actgctggag ccatcaatga
    11461 cataaatttg atcagtagca tggatgtttt atggatgcct aattcaaagc ttgattgaat
    11521 tggtttttca gatagcgttt ctgctacatg accaaatagt gtttcatttc caacagaaac
    11581 aatgattcct tccgcacttc cactgatgac attacttccc ataaagacaa gattttcgta
    11641 acttgtttcg ctttgctgat cgtcttcaca tactttcgca tgcttttcta ctggatagct
    11701 ttcccctgtc aatgctgctt gggaaatgaa taaatccttt gcggacaata aacgcatatc
    11761 cgctggtatc atatcccctg ctgaaagccg aacaagatct ccacagacga tttcttccat
    11821 aggaatctct gtgtactttc cattacgttt tacagctgcc gttactttca caagtgattt
    11881 cagtttttca gccgcttgat tggaacgtac ggactgaatc aacgtcattg tcccgctgac
    11941 gataaccata gtgaagataa tggctacacc gaaaagatct ttatctccag gagctgctaa
    12001 tacatattcc gtgatgaatg aaataattcc taatgcgatc aacactaatg taaatggcgt
    12061 gatgtatgct ttcaatattt ctacaatgaa tggtgttttt ttgccatatg aaatcgcatt
    12121 ttcaccgtaa ttttctcttg aacgttcgat ttgttcttct gtcaatccat ttgctgatgc
    12181 atggaatagt tcaaataatt cttgtttcgt ttttccagca aaagctgcat agattttttg
    12241 tgtatctttc tttttttcca tctcaatctc tcctttgtgt ccaaaagaca gctgttctcg
    12301 ctgcttttgg tctttagcta ttcatcggat cgatagagaa aaaactgaaa ggggctgaga
    12361 acagatagat aatagccctg gcctttcctc tagatccttg tttttcgaat gactgtcatc
    12421 catttgttct catctccttt actaagtaat tttaattcat gacttccaat catttttcga
    12481 atagttattt ttccaattag accacctcct ttttattttt caccgatggg gatttgcggc
    12541 aacaaaaaaa cctctcgcca aatactcagc gaaaggtttg aaaaagcata ttaaaaaaag
    12601 cttctcagat ctcatcgttg agttttgaca ctgtacaacg taaaaagcag atacctgctt
    12661 ttagctacct tatgaaaagc cttatctcga caattcctgt tctacccatt ggcgtctctc
    12721 gacgtttttg ggcagtagcc tatgtttgta taggagcctc acctaacaaa tcttattcgg
    12781 ttttccttcg ttaatataac aactaaaaaa gaggatgtca aatcaatttt ccatgttttt
    12841 catacttttt ttaaaataca cacgttatat tcctgtctca cgcggtttta tttgtctcat
    12901 tttccacctc ccgctataat agaaatatag taggaaacga ggtgctgtta tggaaagaac
    12961 acttgttatt atcaagccag acggcgtgag acgccattta gtcggaagca tcatccaacg
    13021 ttttgaagca aagggactgg ccattgctga aatgaagttt gaaactatga ctcctgaatt
    13081 agcaaaagaa cattatcagc acttgactga gcgcagtttt tttgatgaac tgatcgatta
    13141 catgacttcc ggtcctgtcg tttatcttgt gctggtcggc gaggaagtga tcgatatcgt
    13201 ccgtaagatg gttggagcaa caaaagctgc cgatgctgtt ccaggtacga tccgaggaga
    13261 ctacgcgctg ccggggactg aaaacatcat tcacgcttct gattcccgtg atgctgcggt
    13321 aaaagagatc gcccgctttt tcccgccatt cgatataaac aaaccgtctg aaaaagcggc
    13381 gaagtgatac aaattctaaa ctgctggtct agttgctggg ttcagcaatg gccagcagtt
    13441 ttttctctaa ggacctccgt tgattctttc ctaacatata ttcgagcact gtgaagaatt
    13501 cttggtagtc tttcgtcttt tcttccccta aagcagcaga aatcaatctt tgataataat
    13561 ctgccatcaa tgtttcatag atcactgtac ttctttcttt atgtgctaag ctccgtttca
    13621 tatcttcatt cacactacgt gcctttttca accgaccatt ttctatataa aacgaagtca
    13681 ggttcattaa aaaagtaaag agatactgct catgattgtt caactgtgct aatcgtcgca
    13741 ttcttttttt gattttcaaa taattgttct caatgaaccg atcactgaat atccaaggaa
    13801 aatcagctag aatagatagt tcaaattgac catagtctgg tatctgcatc aagtattctt
    13861 caatgattcg gcattcataa cgtaaaaatt caaattctgt ctcagatact tctgtttttt
    13921 cgaccatgtg aagattcaaa accaaataat acagatcttc tgttttctta aaatgcctac
    13981 ggttattgct gatctcttta taaggatcaa agctgtcttc ttgtacccga tctagcattc
    14041 gtcttttttt ctttaacttt attggttcat ccagctggtt tcgcatccat tcatattctg
    14101 caagtgtcat gttcattcgc tctaaaaatg atctcaatgt tacaaatgac atttttttca
    14161 ctgaatttgt ctcaatcccg actagagaag tcttaaaaca gattccttcc gctaattggg
    14221 actgtgtcaa cttcttgttg actcgaagtt tcttgatcaa ttcaccatca tacataatag
    14281 ttctcctttt taatttaaat ttttccacat tcaataaata gatacgttaa aaaggaaaaa
    14341 tacacgaaaa aaataaaaaa atgttttttt cataaaaaat accaaccttc aagcattaga
    14401 atgttgtcta actactgaag gttggtttga ttgtttattg attatttttt tgctgttcaa
    14461 cgtctgttct tgttactgga tataagttgg ttgttgtttt attaccattt tttgaaaaga
    14521 cacttgtcga atgttcgcct ttttgctttt cgattgcttc attacgttcc gcttc
//
LOCUS       DADGKS010000069        13948 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.070, whole genome shotgun sequence.
ACCESSION   DADGKS010000069 DADGKS010000000
VERSION     DADGKS010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13948
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.070"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            949..1422
                     /locus_tag="JXV47_002247"
     CDS             949..1422
                     /locus_tag="JXV47_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HAX1488265.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1431..1658
                     /locus_tag="JXV47_002248"
     CDS             1431..1658
                     /locus_tag="JXV47_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1488266.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2294..2665
                     /locus_tag="JXV47_002249"
     CDS             2294..2665
                     /locus_tag="JXV47_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488267.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2921..3163)
                     /locus_tag="JXV47_002250"
     CDS             complement(2921..3163)
                     /locus_tag="JXV47_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAX1488268.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3195..4097)
                     /locus_tag="JXV47_002251"
     CDS             complement(3195..4097)
                     /locus_tag="JXV47_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAX1488269.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(4110..4298)
                     /locus_tag="JXV47_002252"
     CDS             complement(4110..4298)
                     /locus_tag="JXV47_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAX1488270.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(4312..4875)
                     /gene="amaP"
                     /locus_tag="JXV47_002253"
     CDS             complement(4312..4875)
                     /gene="amaP"
                     /locus_tag="JXV47_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAX1488271.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(4913..5806)
                     /locus_tag="JXV47_002254"
     CDS             complement(4913..5806)
                     /locus_tag="JXV47_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAX1488272.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(5884..6822)
                     /locus_tag="JXV47_002255"
     CDS             complement(5884..6822)
                     /locus_tag="JXV47_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAX1488273.1"
                     /translation="MRYYFVDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPD
                     DIFVGTEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLI
                     TCIDRKTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAAR
                     KTTENEELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQ
                     RQTEKMIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTG
                     GLPGKSSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(6856..7206)
                     /locus_tag="JXV47_002256"
     CDS             complement(6856..7206)
                     /locus_tag="JXV47_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAX1488274.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(7239..8141)
                     /locus_tag="JXV47_002257"
     CDS             complement(7239..8141)
                     /locus_tag="JXV47_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAX1488275.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(8134..8991)
                     /locus_tag="JXV47_002258"
     CDS             complement(8134..8991)
                     /locus_tag="JXV47_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAX1488276.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            9325..10134
                     /locus_tag="JXV47_002259"
     CDS             9325..10134
                     /locus_tag="JXV47_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAX1488277.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            10174..10671
                     /locus_tag="JXV47_002260"
     CDS             10174..10671
                     /locus_tag="JXV47_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAX1488278.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(11056..11129)
                     /locus_tag="JXV47_002261"
     tRNA            complement(11056..11129)
                     /locus_tag="JXV47_002261"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11093..11095),aa:Ile,seq:cat)
     gene            11316..11639
                     /locus_tag="JXV47_002262"
     CDS             11316..11639
                     /locus_tag="JXV47_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488279.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            11803..12057
                     /locus_tag="JXV47_002263"
     CDS             11803..12057
                     /locus_tag="JXV47_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488280.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            12127..12372
                     /locus_tag="JXV47_002264"
     CDS             12127..12372
                     /locus_tag="JXV47_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1488281.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            12448..12813
                     /locus_tag="JXV47_002265"
     CDS             12448..12813
                     /locus_tag="JXV47_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488282.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(12874..13437)
                     /locus_tag="JXV47_002266"
     CDS             complement(12874..13437)
                     /locus_tag="JXV47_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488283.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
BASE COUNT         4090 a         2577 c         2304 g         4977 t
ORIGIN      
        1 ttttcggaga attaaaaaat acaataaata actttagtta ctttaatgcg ttcttacttt
       61 atttttatat tatcattttt cttattcact tctttggttt atactattct tataaataaa
      121 aacgaggtat gtcctatgat gaaaagattg tactattcat tgatcataac gattggctat
      181 ttgattgtat caaatctagg aaatatggta tttggtatca gtaaagaatt cagttggact
      241 actacattat gggaatctct attctttttc atcttcgtat ttttgttaca aaattatcga
      301 aaaaaataaa catgtgccat ctatctgttg gcacatgttt taggatttat ggtacttttt
      361 attcggcaat ccattttatt tttctacttc ttcttaatac ctctaacact tttgatttat
      421 aaactaatcc aatgcatcta cttgcgctta ttaagctatt tcagctagat agtaccaccc
      481 catgcgtcaa tgcttgattt tccttttgta taacattgta taagcaataa aggacaaata
      541 agtggtgatt acaccaaacc attgaataag aaaaattctg atacgtaaat aaacatgaac
      601 ttgaaaaaat taatgaatcg gttagctact acgtagttgt cttttttctc atacagttct
      661 gttaacttac acttctcttc gctagataat aaaaaatcct ccaactgtat tgtccaatat
      721 aatcccaggc atctaaacta gcattataga agagacacac atagaatcta aaataactgg
      781 ttttaaatgt ttcttacaat caaaaaaagc tgttaaatgc actccacacc ttcatactct
      841 atcatttttt ataaacgata tatttttatt gtttttcgat aaaaaatagt tgttttacaa
      901 taattattct gctatatttt agctatcaaa gataaaagag ggataaaaat gaaatttaaa
      961 acattgctat taaaatttgt cgttttaggt ataagtgccg tatttatttt gttcggcgta
     1021 cttttttata ctcagatcgc tacaagcgaa aaaggattca attttgattg gcagaccaca
     1081 ttatttgttt ctgtcattta ctttgccctt ctcctaggga tcgttattgc ttatttctta
     1141 ttgaaactat tgaaaaaaat cgaagataac caagcttttt ccactcaaag cttaaacata
     1201 ctaaaaaaaa tcgaacgaac cattttgttt attggtttcg ccttttttgg cttacttcct
     1261 aaatttatga aagtagcgga tttagacgat gctccaggtt tgatgttggt aggaatcgct
     1321 gtcgtattca ttccttttgc agtatacaca ttaacaagcg tgctggaaaa actgcttgaa
     1381 catgcgattt tacttaagac agatcatgat ttgacagtgt gaggtgcgac atggcaatta
     1441 tcgttaattt agatgtagta ttagctcaaa aaaaaatgag tgtgactgaa ttgagtgaga
     1501 aagtgggcat tacgatggca aacatctcta ttctaaaaaa tggaaaagca aaagccatcc
     1561 gtttttccac tctcgaaaaa atctgccaag ttttggagtg tcaaccaggt gatttgttga
     1621 cctataaaaa tgactcgaat actataccag aagaataaaa taaagtagaa caaacagtaa
     1681 ataaaaaata atctgaatga tagatgtgtg agacttttag aagttattta cgtctattat
     1741 tcagattttt tatttcgatt gaataccgtt ttatctataa ataagatatg tactgactca
     1801 tacaaagggg gccttttctt ctccatgtac tatcactttt cctgatacaa ctggtttcct
     1861 gttacgttgt agttggatct gcttttagta taatacttta ttcattccac cagactgata
     1921 gcagtttgag cagtctaaat aatcatgtag tattacaggc cattctgttt cataccttga
     1981 agtgcttaaa acttcagcta atggcccatt gtgttaactc ttactccatt cttttttagt
     2041 aagctcccat atatactgta aagccttcta tatattatgt catgttgctt tttaacattt
     2101 actatgtagt tttgataaaa tgatttgaat aacagtgatg gacaattctt ttttattttt
     2161 aacattattt tgataataat gattatttat ttaaaaatac attagataac atttgttacg
     2221 acacgaaaaa gcttcacaaa caaatatcgt tattttaaaa tgagggcgaa ctcacacaat
     2281 taggaggaat agtatgccat ttattgttta cttttttctt tcattactcg tgatctatat
     2341 tccattacca acatttttcc tgctcgtcaa tcgtctagca gagcaacatg atacgattgc
     2401 tgctcttacg aaactttgtt tacttctatt tgtttgtcta gattacttta cgagctatta
     2461 ttggctaaaa cagacaagag taaaaaagag atattatttc ttccttgtct ttttcaatct
     2521 ctttgagttt ctgatccatt gctttttact tcatcagtat catacgatcc atttgtggat
     2581 catctgggtt ttcaaagtgg tcgtattatt ttgtatgttc acctttccta tctcaagaaa
     2641 atttagggag gcattgtttt attaaagaag cttctctgta tcaataaaga cacatttaag
     2701 gaaaaacttt taaaaatcta attgggaatt tgcccgcata aataagaggc tgtgacaaaa
     2761 gtcttgtcac agcctcttat tccgtataaa cagtgttcaa aagcttgcat cttcgataat
     2821 atgcccaacc aaatgaaaaa tatgagaagc tatttttgtt tggctgttct tattacttga
     2881 tgaagaacag ctttttcacg acctcttttt aaaagtcttt ttacagtttt cgagcaaaga
     2941 atgatacgat tagtactaaa atgatggcac caatcaatga tggcacgatt gccattcctg
     3001 caatacttgg tccccaagaa cctaataatg cttgaccaag tgctgatcca actaaacctg
     3061 ctacgacatt tgcaataatc cccatcgaag aacctttatt cgtgattgct cctgcaattg
     3121 ctccgataat tcctccgacg ataagtgacc aaataaatcc catgtttcgt tcctcctaat
     3181 gttttacttc cttattactg aacccgtggt tctgtatttt cttttacttt ttgtgcgccg
     3241 cttccagctg ctgattttac tttatctgtt tgattcgaag caaattcacc ggtttttttc
     3301 gctgcgtcag ttactttgtc ttgcaccgtt tcttgatctt tttcaaattc ttcttttgtt
     3361 ttgatgtcca ctacgttagc gttgacttcg atcacttcta aatgtgtcat attttttact
     3421 tctttgccga ttacttcttg catttcttca aagatttttt cgatatcttt gccatattcc
     3481 acaatgacat ccatatcaac tgctacttgt tttttaccga cttctgtttc gatcccagcc
     3541 gttacattat ctgtattcac aagttttcct gccacattag agaagaaacc accgtttgca
     3601 gataataaac cgtctacttg ttcaattgcg attccgatga ttttttgcac aactttatct
     3661 tcataattca gctcaccgcg cattgaatct tcctgttcag aatcatgctt tccttggtta
     3721 tttgtatgat cagaaccaag ttttccttgt ccgtttgtgt ggtcagaact aagtttttct
     3781 tgtgctttcg catggtcaga aggatgtttt tgctcttcca caggtttaga aggatcgatt
     3841 gcatcatgtt gttctggaac tttagattct ggagttcctg gatgatgagg tgcatgcttt
     3901 tctgcatcat gtttcttctc ttctactcct tgttgaacgt tagggactac tggatctgga
     3961 tgtgcagata ctggtgctgt tttgttcttt tcatcgttca caccatttga ttggtttggt
     4021 gtcgttgggt ctggatgtgc agacactggt ttttggttgt tcattttatt gttattattt
     4081 ttgttattgt tattcatgga tgtttcctcc taagatttaa aatagtgatc taagattttc
     4141 gtttgtttca gataaaaacc gatagcgacg ccgatcgctg ccatgatcaa gatcaataag
     4201 gtcttgaaaa agcccacggt gatccataaa acggctaata tcaatccaag taccccaaag
     4261 atgataggga gcttgtatgt cgaaaatagt tctttcattt ttggtccccc cctattctac
     4321 tcgtttgcgg tcattgcttc gtttagctgg ttcttcaaag cctgtgtatt tcaccgatac
     4381 tttcactggc tcttttgttc ccaatatgtg ttgtacttca ttttcgattt ctttcatcaa
     4441 tgttcctgtt ttaccaatga gtgctgaagt tcgtttcaac tcccctttta cattgacggc
     4501 gatcttgttt ttcgttgctt tgacatttac ttttggtgaa tggatgaatt catcttcatg
     4561 caagtgagaa cgaaccattc cttcaattgc ttttttatcc aacgtcaact ccccatcacc
     4621 atgtttcagt agaaagtttc cgattgtttt tggataaaac aggaaaacaa gtaacgtgat
     4681 aattgtcaaa atagcaaatg caacggcaag ccaaaataca tattgttgca cgtatgaatt
     4741 agtgatggaa aagaatcgaa acttctctag ctgaaaaggc aatggatagg ttgcacttaa
     4801 tagtatcgca aacaaaagca cagatagcaa aagtaatgtt ccgatcactc cgatcgtttt
     4861 tacaccttta ttcattttcg cacctcctca taggggtgaa acgatcaact tcttataagt
     4921 tgatcgcttc tccaccagtt actccgtaaa tttgggctgt aacataactt gctttattcg
     4981 atgctaagaa aacataaact ggtgctaatt ctcctggctg acctgcacgt tctagtaaac
     5041 tttgctgacc aaattcaggg atcgaatcag aaggttgtcc ttcgtctagt tgtaatggtg
     5101 tccagattgg accaggtgct acaccattta cacggattcc tttaggtgca agctgttttg
     5161 ctaaaccgat cgtaaagtta gcgattgaag cttttgttgc tgcgtaatct aataaatgtt
     5221 cgcttggatt gaatgcttga acagaagttg ttgttacgat tgctcctcct gctgggatat
     5281 gcggaacagc ttctttcact aaagcaaaca tagcgatgat gtttatcata aatgtgtctt
     5341 tgacttgctc aagtggtaac tcagcaatag actgacaaga aatttgctgt cctgcgttta
     5401 gtaccatcgt atctagcccg ccaagttcac tcacggcttt atctatgatt tctttaggtg
     5461 cttgttcgtc acgaagatca aaaggtagta agacaatctt acgtcctgca actttcacgt
     5521 attttgctac ttcctctgca tctttttctt ctcctgggaa gaattgaaga gcgatatctg
     5581 ccccttctct agcaaatgca atcgctgctg cacgaccgat ccctgaatct ccaccagtga
     5641 ttagtacacg gcggttttct agttgattat tgccttcata ggattcttct ccacaatcag
     5701 gaacaggaat catattctgc tgtaaagctg gtgtatcctg atcttgttta ggaaatttct
     5761 ccgtatggta caagtttcgc gggtcgatta attttggttc tgtcattgct gtattcctcc
     5821 tagtttttaa attgtattgc caaaacaaat ttctttgttt gatacctgtt ttaaatagat
     5881 tctttaattt gtataatctt tccggtataa atggtaacct aaaactactg ctgctatcaa
     5941 agagccaaag actacgagta taaagcctag agcagaactt ttacccggta atcctcctgt
     6001 attcattccc caaatccctg cgaacaacgc cggaacggaa atgattaatg cagctgaatc
     6061 tagatatttc atgatatgat ttagattatt gtccatcatc ccgttgaata gatcaccaat
     6121 actctctaat aaatctcgat agatctcgat cattttttct gtttgtcgct gtctcaaatg
     6181 gacatcatag agtagctgtt catcgtctaa acgtttgatg aaagtttcag aattccataa
     6241 ttgatccatt gtttcccgtt gatctcttaa ggtatgatcg atatatacga tgtctctttc
     6301 aagatctgcc tgtttataca gttcttcatt ttccgttgtt ttacgagctg ctttatccaa
     6361 agcgtcaatt cgctttttca tctctcttag ttctttcacg taatgggtgt aaatatctaa
     6421 taatgtatac gtgatgatct tttcaaacga gtttaaatga tttccatgct ttgtcagcag
     6481 ccgatccaca aattcggttt ttctatcgat acaagtaatc aagagattat cggaaagtac
     6541 aaaagatatt ggcgttaatt ttttttcgat acgattatct gactgatcta gattaatcac
     6601 taccaaagaa aatggatgct ctagtttcgt ctcataaagg cgctccatcc gagaaacttc
     6661 ttccggatat tcggttccta cgaaaatatc atcaggaagc tcgaattctt cgattgcttg
     6721 ctcaatctct tcgggctttg cactatcaag tacgagccaa ttatattttt tttcatctgt
     6781 ttctattaca ttcttttctt catccacaaa gtagtatctc aatgtatacc tcctttttgg
     6841 actttctcga aactattagc tgaagaagca gttctttaat ttgatattat aatcgagtac
     6901 tgcgatttca ttttctaatg aaaagctgtc aagctgtttg ttgaagtcca tgttcaatcg
     6961 tttaccgaaa taattttgct ctaatttaga tgtatagatg tccaataatg gatgctcgat
     7021 tttagtcgca tattctccaa attccgaaac aaaaggaatg atttgaaaaa agctgccttt
     7081 tgcaaaagca cctttgtccc ttagaaatgg atcggaatca ttgataagcg cgagtgcgat
     7141 ttttgtattt tccccaacct tttcaattaa cgtctctact gcatttttag acattgtaat
     7201 ttccattcct actccccctc ttcagttgtt gtcttctatt atttaacaac tacatctgtt
     7261 tttggttgaa cttttgcata ttttggatat ttagggaatt tagctacaca acggaaagcc
     7321 gtcatccctg catatttttc gtaatatttc ttcgttggcc cttcaaaatc cttgctccac
     7381 ggtttcacat gtcctgaaaa atggataatg taaggattgt tgcgagtttc ttcgtattca
     7441 cgttcacctg ctgctgttgg atgttttttt gcttttgcca tgatatagcc ttgtgcattc
     7501 caacgcggat gaagtggtaa ccaacggtca tgtaagatag catttaatgc atcttggtca
     7561 tggaatcgta atttttctgg attatgttcg atgaaatcta atactttttg cgtaatattt
     7621 tcatctaacc attttttcac attgatcagc atcaaacctg agttgaaata acgcattgat
     7681 ttagctgaaa ttttcatttt ttccagtcgt tgatggaacc cagcgtcttc aacagctgct
     7741 acgattgaat caccgaagtc aagacgccat aatttagaga tatcttgtaa agcgatcatg
     7801 tcgcaatcca tatataagat acgttcaact tctgtgccgc ggaacaattc cggaatcgca
     7861 atacgataat aagctgtttc tggaatacga tcgctgatta ccacatttgt aaagaattct
     7921 ttattgattt tcaagaattc cacatctgag ttcattcgtg cgtttttcac tgagaagcgt
     7981 aaaagctgtt tactttcaaa atcgatatca tcgtcaatca catagaaccg aacaaattta
     8041 gacgggttgc aattatctaa tactgagaca aataatgcag ctaaatgtgg tacgaatttt
     8101 gtgttacaac ttgcgactac tgctatttct tttttattca ttgatctcgc ctactttcgt
     8161 tagagtactg tgtgctaatt tttttaagta taaattggta tacggatgat ctttcaacgt
     8221 attccaaggt ttatcatgtc ctgtaaagtg aacgatcgaa ggtttttcat ttccttcttt
     8281 atactgacgt tcatattttt catttggtgc tggatgacgt tcaaaaatca gcgaagtctg
     8341 catgttccat tttggatgaa gttgttccca atcttcataa agtacagcat tcaaagcatc
     8401 ttggtcgtga tagatgattc gatcgccatt ttcactgagg taatggatag ttttttctgt
     8461 aatttctttt ttattccatt gatcaatgtc aatcaccatc actcctgaat tgaagtacaa
     8521 gtcatcggaa tcgattccta atctttccaa agctttcact tggcctggat cgataatagc
     8581 gccgattgtt tttccattta acggctcatc atatagtttt acgatatcgt ctagtactaa
     8641 cacatctgaa tctaagtaaa ggactttctt ataatcctct ttagctaata agtttggtaa
     8701 agaaattctt aagtaagcgg tagttgtgat atggtcactg actaggaagt cttcgtagat
     8761 atctttttcc actgtcagga attggatact tgcattactt gaatatttat ttaccgtttc
     8821 ttccaatcct tctttactat attctgatag accatcgtca atcacataaa attttatgcg
     8881 tcttgtttta ttgcaatttt ctaatgcagt tgcgatcatc acgctcaagt aaggagcata
     8941 attttcgtct gaagcagtta ccacaggaac tacgccgtat ctcttctcca tcaaaatcac
     9001 tcctttttct aatctttttc taacctgttc tacatctaga atattcctca tttggtttta
     9061 aagcaaaata tatgctttgt tttcattgaa tattttaaaa tttttttatc acaaaacgca
     9121 tcggtaagcg ctaactattc gtttttcatg gctttttatt caaaggtatt gaccaaaaac
     9181 tactatatat agccaccttt ttcttaagaa tgttttttga aaaaattcat aatgacaaag
     9241 caagttagtt tcattttttt aaattctcat ttaatcttaa ggtaacagga aaatagatat
     9301 gtaaaaagaa agtaggaaga taaaatgaaa ctagcagcga ttgatttaga cggtaccttg
     9361 cttgatcgaa atggaaagat accagaagaa aatatccaag cacttcggaa atttgatgaa
     9421 aatggcggaa tcgtaaccgt cgctaccgga aggaacagca tttctgctaa agatattttt
     9481 tccgaattag gaatcggtgg ctatttgatt tcttccaatg gttcactgat tgctgaaatg
     9541 aaggatggaa aaatggcgaa agttctcaga cgttcaaaaa tagatagcga tacactgaga
     9601 aaagccttct tctatgctca agaagcgaaa atatccatca ttgctagccg agaaacccaa
     9661 gatgatcagc tgacattcga tgaatcaaat ctagtcaaag atgaccctta ttatgaacat
     9721 ttcaatttac agaaccattc ttttgatcaa attttaaata tgttggaaga tccttctctt
     9781 agctatctta aattagcatt aacagataag agtgaagaaa aactacagaa gctacaaaga
     9841 gatctgcaag cagatggtat ccaatcagta ttctctgatc cgcatttctt agaaatcacg
     9901 cctacaggta tcactaaagc tcattcactt gtttttctgg cggattacct tggaatcgaa
     9961 tcgagtgaca tcatggcttt tggcgatcaa gaaaacgaca ttgctatgtt gaattacagc
    10021 gggttgagta ttgcgatggg gaatgcacag cgacaagtaa aagaaattgc aaaccaagta
    10081 acactgacga atgaagaagc tggtgttgct tatattttaa aaaacttcta ttaaaaagaa
    10141 taaaatgacg atatgaatgt aggaggaaag aaaatgttag ttattattga tatgcaaaat
    10201 catattcttg atccaaacag cgaattttat attccagagt cagatcaatt ggcagaacgt
    10261 attgctcaaa gattagctaa agcacgccaa aataatgaat atattctctt cacacgggat
    10321 ataccagttg aactgaagga caaagaagaa gaacgagaag atttgcaatt gatccctctt
    10381 ctttctccac aagaaaatga acgagtgatt aaaaagtatt actttacgat tccacctgaa
    10441 actttagctg aaatccagga aactttattt gaaagcaaag aagaacaaaa agagatcgaa
    10501 gtagtcggga ttgaaacaaa cttgtgtgta ctctctaatc tgataggcct gcagagtgct
    10561 tttcctgaag cagacttttt tgttgatcca atgttagtct ccagtagaaa acacggagaa
    10621 tccgctttag agctgttgaa agatttcaac gtctctatcg tcgaatcata aaaatatcta
    10681 tcttcattta cgatatttaa cacacaataa aaaaagcacg cagaactgtt ttagtcctac
    10741 gtgctttttc tatcaaagta gattggcttt tttatgacac agagtgaaac ggcaggctca
    10801 cgacctcttt cttaaatggt gttcaatcag ctgaccctcg gtattagctt aacaaacggc
    10861 aaaatatgag gaactatttt tccgtttgtt aagctaatac tcaggtcaaa acgctgattt
    10921 cacaacctct tccttaaacg gtattcaaaa gcttgcatct gcagtaataa gaacagccaa
    10981 gtaaaaacat aagaagctgt ttttacttgg ctgttcttat tacttgatgc agggcagctt
    11041 tttcacaacc tcttatgtac cttgtaggac tcgaacctac gaccggacgg ttatgagccg
    11101 tctgctctaa ccaactgagc taaaggtaca tcataaataa aatttatttt tgttactttt
    11161 caactatagc acgaatgaca aactctcaca agtttcaaaa tataagtaaa ataatattgt
    11221 tattcttatt tcttttactt gtgtcataac tattttgtta ctttaatttt tatttgctta
    11281 ttttagaaaa aatgttattc ttttatttat tctcaatgtt aggagtgatt attttgccat
    11341 ttattgcgat tttattcgat ttagttgcgg cagcagctta ttttctccaa ttaaattatc
    11401 aaacctcagg aattctgttt attggaatga tttttcaagg tgtgattacc cttttgcttc
    11461 ttgtcatgat gctcagctat aaaggaaaaa gatatgcccg tattcaaaca aaagtatttg
    11521 ttaaatatgt ttccattcgc tatgggatca tcattctttc ctttttagtg aatgcgatcg
    11581 tcctcttttt atatgtattg aattacttag atatcaatcc attgattttt tctcgataga
    11641 taagacacat tcagcggaac agttcctgct tatcagcaga aaactgttct gctttttcat
    11701 ttttcattga tctattcttc ttttattttc ctagcatttc atttgtgatg tatgcaataa
    11761 catgttatct tttattatat gaatcgttga ggagtccgtt acatgattac gttggtgaga
    11821 gttttgtttt gggtgcctgc ggtcgcactg gtcgcaagta ttgtttatct tatgaattgg
    11881 aacaaagaac ggttttattt agctattttg actcttccgg ctatctactt tatgtggaaa
    11941 gtttttaatt acaactactt tgaacccgat agtgttttta tagaagaatt atcaggactg
    12001 gttttgtctt tattgatcgt cattctttat ttgatacgtt taaataaaaa acattgagta
    12061 ctattgattg catgtgtagc tttctatagt cattataact attctactat aatgaaaggt
    12121 gattaaatga gtatcgaaga agctatttta ctggatactt tacgttgtcg tctgaatttc
    12181 ttaagaactg gccgatcttt atctcaagta gctgtttcta gcgcgttaag tattccttta
    12241 ttcaaatatc gtaagtacga agaaggagaa gaaattccaa gcatcattga attaatctat
    12301 atcgctgact tttacgatat ttccgttgat tacctaattg gtcgctcaga aacagcaagc
    12361 aaactgaagt gattttttcc agccttggtg ctggtttttt catttaacgt ctaaggttaa
    12421 caatctatat ataaaggaga catttctatg cgattatggc atgaaaaatt gatttcaaag
    12481 cttcctcgtc aacagctttt aggacaacat cgggaatgct gtgcattaag aggaaatggc
    12541 tggggaaaga aacatgctac tgtggattat gtttttcact attctcctta tagattattc
    12601 caatatcatc agcttgtcat ggatgaaatg gaaaaacgtg gttacagccc agcaccagag
    12661 tggaaaaatc ctatgtatcg tggcaaatca tgcgaagcat tttttgattt acctactgta
    12721 gagcgcaacg tgccgattta tccggaacac gatgaagttt atctagcaga atgtttagca
    12781 aatttggagc aaaaaggaat ttatcttacc taatataact agaaaagcct tctatctcct
    12841 cttacttcat taaaaagctt taaccatctt agatcaagct aaaatgtcgt aagttttagg
    12901 gttatcttca tcctcacgtg caaaactaaa agcgtactct agttttggtt catcgccaac
    12961 ttccctagac ataaatgaac atctcctgac gtggtttaaa agtaccgcat cttcgacgtc
    13021 tgtatacgat gcacagcaca gattgcttct tttgatcttt cttttgattt ttctgttgct
    13081 tcttctacac cttcttcgat tactacatcg atgcttacaa ttgcttctgc ctaatattcc
    13141 catgcatcgt cgatttaagc ctctgtagtc actgtgatcg tttccacatt ttaactcctc
    13201 tgtcgtggct tcagttgatt ttgtgatcag ttcagttgct aagccagagt cagaacaacc
    13261 tgccattgct agcgttaata ttgatagtaa aaatagtttt tttatcataa ggttcccccc
    13321 ctgaaaatag actaaaataa taacgctttc tttttttgtt ttcagacgaa aattaataat
    13381 ttctaaatat tctttaaaaa agcttataac tattatgcct tttttaatat ataacacagt
    13441 tatttttaaa aataagaatg ctaaatcact ctacaataac ggcgaaagca caaaaaataa
    13501 aaaaattatt acgttattaa aaaaacagat gaaagatcag gttttattag atctcattct
    13561 ttcatcactt gaagggattt aatgaactac tttttcctct ttgtcgtttt tatatattcg
    13621 tattccttca aacagtagga tagcctcttt caatgcttga tatttgaact gtccgttact
    13681 taaaaattta gatgtgccgc cctcttccta gaacatattc ttttttactt tttcattaat
    13741 tgacagacca atcgaacgaa actgtaaatt tcgataggat aatgattggt caaactcatt
    13801 cattttcaag acatctcgat tcatattcaa gataggaatc tttttatcaa catcacttta
    13861 ttcgtatttt cctctaccat aaaagcttca cgctccacaa aattgtttta tacactacta
    13921 ttcagcccat tcaacgacca atgaattt
//
LOCUS       DADGKS010000070        13808 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.071, whole genome shotgun sequence.
ACCESSION   DADGKS010000070 DADGKS010000000
VERSION     DADGKS010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13808
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.071"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(162..2159)
                     /gene="tkt"
                     /locus_tag="JXV47_002267"
     CDS             complement(162..2159)
                     /gene="tkt"
                     /locus_tag="JXV47_002267"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HAX1488284.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2261..2512)
                     /locus_tag="JXV47_002268"
     CDS             complement(2261..2512)
                     /locus_tag="JXV47_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HAX1488285.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2659..3282
                     /gene="lexA"
                     /locus_tag="JXV47_002269"
     CDS             2659..3282
                     /gene="lexA"
                     /locus_tag="JXV47_002269"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HAX1488286.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3462..3680
                     /locus_tag="JXV47_002270"
     CDS             3462..3680
                     /locus_tag="JXV47_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488287.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3969..4481)
                     /locus_tag="JXV47_002271"
     CDS             complement(3969..4481)
                     /locus_tag="JXV47_002271"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HAX1488288.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="JXV47_002272"
     CDS             complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="JXV47_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HAX1488289.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6934..7368)
                     /locus_tag="JXV47_002273"
     CDS             complement(6934..7368)
                     /locus_tag="JXV47_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HAX1488290.1"
                     /translation="MKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPLILV
                     IIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQREFRN
                     ERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7378..8166)
                     /locus_tag="JXV47_002274"
     CDS             complement(7378..8166)
                     /locus_tag="JXV47_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAX1488291.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8163..9104)
                     /locus_tag="JXV47_002275"
     CDS             complement(8163..9104)
                     /locus_tag="JXV47_002275"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HAX1488292.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9281..9868)
                     /locus_tag="JXV47_002276"
     CDS             complement(9281..9868)
                     /locus_tag="JXV47_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HAX1488293.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10089..11402)
                     /gene="obgE"
                     /locus_tag="JXV47_002277"
     CDS             complement(10089..11402)
                     /gene="obgE"
                     /locus_tag="JXV47_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HAX1488294.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11690..12700
                     /gene="gap"
                     /locus_tag="JXV47_002278"
     CDS             11690..12700
                     /gene="gap"
                     /locus_tag="JXV47_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAX1488295.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12785..13720)
                     /locus_tag="JXV47_002279"
     CDS             complement(12785..13720)
                     /locus_tag="JXV47_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAX1488296.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         3808 a         3096 c         2435 g         4469 t
ORIGIN      
        1 ctcaagaaac acaaactaat ccgaagaatt ctttgttttg tcatttaaat gtaacatagc
       61 cgaaaacgaa aagtaatatt gatttattct tctaacacat aaagaacagc tgtctccaac
      121 ttgcagacag ctgttcttat cagtcaaaca attgcttgga tctatgatag ttgattgtac
      181 gtattcacga cattttctac tgtaaatcca aattcttcta aaattttagt gccaggggca
      241 gatgcaccga aatgatcgat tgtaatcgtt gcgccctctg ttcctacgta gcgttcccat
      301 ccaaatgatg cagcagcttc gatagccaca cgtttcttca ctgatttagg aagtacactt
      361 tctttatatt cagaagattg tttttcaaag aggtcaaagc ttggcataga aacaacagaa
      421 acatctttgc ctttttcagc caattctttt tgagctttca cagccaaatc aacttcagaa
      481 cctgttgcaa tcaaaatacc ttctggtgtt tctccttgtg atggagaaag aacatacgcg
      541 ccttttttca ccatttcatc tgctacttct tttgtagaag gcaatactgg aaggttttga
      601 cgactcaata caaggatagt aggcgcatct gttgtctcca tcgctacttt ccaagcagca
      661 cgtgtttcat ttccgtctgc cggacgaatc acttgaacac caggcatgca gcgaacagat
      721 gctagttgtt caatcggttc gtgcgttggt ccgtcttctc cgacagcaac cgagtcatgt
      781 gttaagacgt aaacaacagg agtatgttgg attgctgcta aacgaactgc tggtcttaga
      841 taatcgacaa agacaaagaa tgttccaccg tagatacgag ttccgccatg aagttggata
      901 ccattcatag ccgaagccat tgcaaattcg cggacaccga accagatgtt gcgtccttca
      961 taatgttcag gagtgaaatc tttatctgca gccaccattg tattattgga acctgacaag
     1021 tccgctgaac caccccagaa gcttggtata gctttcgata attcttggat gacttcttta
     1081 cttgaaacac ggcttgcttg actgcttcca acttcataag ttggcaattc tgcatcccag
     1141 ttttctggta gtttgccatc aaaagcatct tcaaattgtt gtgctaattc aggataagct
     1201 tttttataat tggcaaacat ttcattccat gcatcttcag ctttttgtcc ttcttctatc
     1261 atcgtttgat ggaagcgggc agctacttct tctggaacag tgaaatctgg atactcccaa
     1321 ccataaactt ctttagccat cttgatgcca tcttcaccaa gaggagcacc atgaacagca
     1381 gatgttcctt ctttaggagc accatagccg atgactgttt ttacttcgat caatgttggt
     1441 ttgtctgttt cagcttttgc ttcttcaatc gctttagaga ttgcttctag gtcatttccg
     1501 tctttcacta agatatgttg ccagccatat gcttcatagc gagcaccaac gttttctgtg
     1561 aaagcttttg aagttggacc gtctagtgaa atatcgtttg aatcgtataa aacgatcaat
     1621 ttccctagtt tcatatgacc tgccatcgaa cttgcttctt gagatacccc ttccatcaag
     1681 tctccgtcac cgcatattgc atacgtatag tgatccatca cattaaagtt ttctttgtta
     1741 tacgttgctg caaggtgcgc ttctgccatt gccataccga cagccattgc aatcccttgt
     1801 cctaatggcc ctgtagtggc ttctacacca tctgtatgat gtacttcagg atgtcctggt
     1861 gttttagaat cccattgacg gaattgtttc aaatcatcga ttgtcacttg atagccagct
     1921 aaatgaagca agctatacaa cattgctgac ccatgtcctg ccgaaagaac gaaacggtcg
     1981 cggtcagccc agttttttga tgtcgttgga tttactttca ggtgttttgt ccataacgca
     2041 tatgccatag gtgctgcgcc catcggcaat ccaggatgtc ctgagtttgc tttttggact
     2101 gcttcaatac ttaatgtacg aattgtgtta acgccaagtt ggtcaatttt gtcaaacaaa
     2161 ataacccctc ctattaattt aggttttttt tacctttatt tcttacactt tcattctata
     2221 agatgtcaca cgaaaaagca atctttttca gtatttttta ctaaaagttg tcatttcggt
     2281 tgtgtaagcc ttttttcttt tggatttctt ttaatttttc cggggtcacg tcattgccct
     2341 caggatcgac gactttcatt ccttcgatat gatgacgcat accggaacga aaagcttcca
     2401 aatactcttt gcgcaagttg atttgttctt gttcttcggc ttttgagaga ccattttcct
     2461 tctttttacg tgcaagttca ttgatccgct ctattttttc aggtgacagc atgctcagcc
     2521 ctccttttac tctccttcat attatataaa aactgaaaaa aaaacaacta gataaactaa
     2581 ataaaatacg aacattcgtt tgatttagcg ctttttatat ggtactattt atttatcaag
     2641 tgaaagaagg tgtaccttgt ggcccgacaa actgaatcaa gacaaatcga agtcttacga
     2701 tatatccatg aacaagtaac ccaaaaagga tacccgccga ctgtccgtga aatcggggaa
     2761 gctgttcagc tttcttctac ttctactgtt cacggtcatc ttgcacggct tgaaaaaaaa
     2821 gggtttatcc aaagagatcc gacgaaacct cgtgcaatcg agttgacaaa acaaggttta
     2881 gaaaagattg ggattcgtcc aacaactatt ccagtacttg gcgtcgtaac agctggagaa
     2941 cccattttag cagtagagga tgcttcagac ttctttccaa tccctcctaa tctttcttcc
     3001 gaagaaggca gtctctttat gctgacaatt cgtggagata gtatgatcaa tgctgggata
     3061 ttggatggtg acaacgtgat cgttcggaag caagaaactg ctcaaaatgg cgatattgtc
     3121 attgcaatga ctgccgagga cgaagcgact tgcaaacgat tctataaaga aaaaaacttt
     3181 ttccgtctgc agcctgaaaa cgacttgctc gaaccaatca tcttagatca agtatctata
     3241 ttaggacgag tagtaggact ttatcgtagt catatctatt aattgctact aattaaaaga
     3301 aaacttttta aaaagagttt gagacgttgg tctcaaactc ttttttcgcc cgggttcttc
     3361 ttctttcaaa tttttatcac ttccctcttt acaaaccgaa caaatattcg tatactaaat
     3421 atacgaacaa ttgttcgcat aaattaaaga ggtgagaatt catgaaatca atgagacgtc
     3481 ttggcttagt attaactgtt ttgtttttag gtattattat tggtaatttc ggcatacgtc
     3541 cagctttact tgtgtttgtt ccgttattta ctttgtggtt catgttgtgg gatgaaaaga
     3601 agtaccgtca atctgagcgg cgcagaattc atgaagatca tttctatcat gagccctact
     3661 acagatccag gcaatcataa taaggattga ctgctaatta ttcaaaagac aagaagttaa
     3721 acttttacgg gggtgtgaca aaaatcggtc acatcctttt tttcgaataa acggtgttct
     3781 aaagccagtt tttcggtatt aagtcaaatt gcggaaaaag tgatttttta aacttctact
     3841 ggtctttgct tgtttccatt tataaaaaaa tagcgaccct caaaagtcag atagagaatc
     3901 tgacttttga gggtcgcttt aaaatcgctt ctttaagaat aacatcaaga atagcttctt
     3961 ttttctgctt aatattccat taatgtaatg atgtcatatc ctttgatttt gtcgcgtcca
     4021 tggagatcca tcaattcgat caaaaatgcg cagcctacga ctacaccgcc taattgttcg
     4081 atcagttcga tcgtcgcttt gattgttcct ccagtagcta gcaaatcgtc acaaatcagc
     4141 acacgttgac ctggtttaat ggcatcctta tgcaatgtca atgtatctgt tccatattct
     4201 aatccataag tcacttcgat ggtttctcga ggtaacttcc cttttttgcg gactggggca
     4261 aaaccgactc ctaactcata agcaacagga catcctacga tgaatccacg ggcttctggc
     4321 ccaactacca tatcaattcg tttttctttt gcataattta cgatttgttt agtagcttcc
     4381 cgataagcgt caccatctgc catcagtggg gaaatatctc gaaacacaat tccttttgac
     4441 ggatagtcgg gaatactggc aatataatct tttaaatcca ctctttgttt cctcctaggt
     4501 tgttaaccat ttctttatgg taggaatatc gctcaaaagc aaaaattcct caactttgat
     4561 tttattgagc cgtcgctggt ataatctgct ctcagtcaaa ggatgacttt ctgggctagc
     4621 gactttttgt aaaacaccgt tctctattgt aacaaatttc aattcaaaaa acacctgtat
     4681 cataaaaatt aataattttt cagggatacg caaatattga gctattgctt ttattttatg
     4741 acgtatatca attcgttctt gagaatggat caatttaaac aattttgcgt actgttctct
     4801 tgtgcctacc ccattcaaat aggcctcatc aggtgaaatc cccatcagat aaacacgatt
     4861 gaatgaataa gaccgaaaaa cttctttcag atccgctaaa tcatctggac aatccataac
     4921 aactagagag tttggttttc ttttttcaat tattgccttt acagaatcta gtccttcgaa
     4981 aacaatcgca gcttcctgga taatctcagg cacgaatttc aacgtcgaag aatcaaatgc
     5041 taaataaagg ctaccttccg acgttcggct ctgttcacgg aaacgttttg cccgccaatc
     5101 aaatacttgc agaccaccca cagaaaaatc agataccatc agctgcggtt tcttacgccc
     5161 gttccattca ttgatcgaaa gctttcctac cacatctacc tgattattca gcagttcttc
     5221 ttcttgagta ccaaaaccaa aagcgaccgc atcaagctga ctcgatgcat cggaaaggac
     5281 aaatttcaga tgctgttggt ttgctccgat tcttttgata ttttctgctt ggacttgtcg
     5341 aaataaaaac tgaggcaaag gattatccgt accaaatggc gccaatagtt tcagctcatc
     5401 aattcgctct actgttactt catttggcag caatacttca tcaattctca actcaggccc
     5461 tctcatcaag tcaatttgat gatcgactat atattggttc atcttctcct gtagtatagt
     5521 gacattttca cttggcatcg ttaaaccgac tgctgcatga tgtcctccga agtaagtaaa
     5581 taaatctcgc atctggtcaa gcatttcaaa aagattcaag gcttcaatac tacgtccaga
     5641 tcctttagct gatccatctt cttttaaagt aaggacaagc gttggtttac ccgtttcatt
     5701 cattattttc ccagcaacaa tgcccaaaac gccttcatgc catcctcggt ttaccaatag
     5761 atggatatga ttctccttat tgaccatcgc taatgcttct tgtgttatct gctctacgat
     5821 tgcttttctt tcttcattga tctcattcaa tttttttgct tgaacggatg cttcctcttc
     5881 atcaaacgtc gcaagtaacg agacggcagg acgtggatcg cccatccgac cgattgcatt
     5941 tagtctggga gcaatcgaaa aaccgatcgt tgtttcgtct gcgtccctca tttttacgcc
     6001 gctttcttca aatagcgcct gaagtcctat ccgttctgaa tgatgaatgg catcgattcc
     6061 taatgaaaca aggattcgat tctcatcagt caatgaaact aaatcggcga tcgttcctat
     6121 cgctactaaa tccaaaaatt ctgcaggcgg ttcttccaat aatgcagaag ctactttgaa
     6181 tgctactccg actcctgcca aatctggaaa tggatagtgc cccgctggat gacgagggtg
     6241 aacaatcgca taagcgtctg gtaaattctc aggtagttcg tgatgatctg taatgatcac
     6301 gtctacacca gcttgctgag cgtatgctac cgcatcattt cctgctaccc cgttatcaac
     6361 agtgatgatc aactggattc cttcttcgat cttttcttgg tataccgatt ggtttggtcc
     6421 atacccatgc tcaaatcgat ttggcaggaa tacttctact tctgcaccaa gtaattccag
     6481 tgtttctttc attaccgttg cactggtgat cccatctgcg tcataatcac cgtaaacgag
     6541 gattttttct ccactgatta cagcttcttg gattcggctg attgctttat ccatatcgtg
     6601 tatcagatac ggatcatgta attcttgttc ctttggatgt aaaaatcggt tgatatcctt
     6661 ttcctcatgg taacctcttt gccacagtaa cttaccgaca aatggagata atttcagttc
     6721 acggatcatt tggagaaagg attcagaagg ctctgtctcg cttaacttcc aatcaaaatt
     6781 tgcttgtctc actttctcac tcctaactta gttattatag caaaggaaat cagcaaaaaa
     6841 aagcagaaag aaagaataaa aacagatcag atccgctaga cagatgttca gcaggacctg
     6901 atcttttgta cgaccattta tgaaatatcc ctattagtca aaataattga agctttgttt
     6961 gggcgattga gttttttgtt cttccggcgc tttcaattga ctgatttgtg cggttttcgc
     7021 ttgtaactcc gcctgataag cagcttccaa ctccgcacgt tcgtttctaa actcgcgttg
     7081 ctgttcttct tttgcttctt caattttctt ttgaagttct gtttgatatt ctgacatttc
     7141 ctgagtcagc tgtttgattt gctttttttg ctgccatagt gttgccgaag cagtcaaaaa
     7201 tacaatcagt gcaccaatca gcgcagaacc gatgatcact aagatcaatg gcgcagaaaa
     7261 ggaagtgaag ccaaaactta caggaacatt tttattgttc aatacagcaa aaagaacaat
     7321 aatcaaaact aaaacaaatc caagaatcac attgctttgc tttttcaatt ccttcaccta
     7381 ctttttgtta aaaattccgc tggctaaata atcaccaatc gttggaaaca gcgtataaaa
     7441 ttttgatgca acttctaaaa taaacggttg attgatttcc cgttttggat gtctcatatt
     7501 gcggacgatc atttttgcca acttggcagg ttctaaaacg atttgtccga ctttttccaa
     7561 atagcttccg cttggatcag ccttatcgaa gaaatttgtc tcgattggac ctggattcac
     7621 tgtcgtaaca gctacgccaa gtggtttcaa ttctaatcgc aaagcgttgg agaagccaag
     7681 gactgcaaat ttcgtggcag aataaaccgt tgattttgca gttgccattt ttccagccat
     7741 agaggcgata ttaatgatat gaccttgtct tctttctgcc atatcgatcg caaatttttg
     7801 tgtcaaaacc atcattccta agatgttgac ttcaaacata tcgtatgctt ttccaaggtc
     7861 gaatgtaagg aagtcttcga aaatcccaaa acccgcattg tttaccagaa tatcgacgcg
     7921 cccgacttct tccatcacct tttcatataa ttcgtccacg ctttcaggat tgctgacgtc
     7981 taccttgaaa gcataagcct ctttgccgct caagcgtctg cactcgtctc tgacaccttc
     8041 tacaaatgcc attcttcgtg cgcaacttat aacgattgct ccttgctttg ctgcttcata
     8101 acagatttgt gcgcccagac cgcctgaact acctgttact aaaacaactt tatcttctaa
     8161 attcatgcct cttcctcctc gcgaaatgga atctcaatgc tatcaaaatc tttcataatc
     8221 gtcgtgtttt caaacacttc ttgtgcttct ttttcaagct ctaaagctgc ttttcctaaa
     8281 tatctcgcac tgatatgagt aagtagcagc cgttttgcct gcgcttcttt tgcaacttca
     8341 gcagcttgat gagtcgtgga atggaaatag ttgtgcgcca ttcttgcttc atctttatta
     8401 aatgtgcttt catgtaccag aatatcgcta ttttccgcaa gcacaacgga attatgtgtt
     8461 tttctcgtat cgcctaaaat agtcacgatt cgtccttttt tatctggacc tacgaaatct
     8521 tttccattga tcgtccgccc atcttctagt tggatcgttt caccttgctt cagtttgccg
     8581 tacagtggtc cagctggaat acctaattct tttagacgat ccacctgcaa ttctccttta
     8641 tgatcatgtt caaccacacg ataaccaaaa ctgtcgatcc catgatttag tttttttgta
     8701 taaacagaaa attgctgatc agtaaaaatc ggggctgttt catttagctc aatgaatttc
     8761 agcggataac ttaaacgcgt ttgcgaaata cctaaagaga cttttatgta ttcctctatc
     8821 ccttttggcc cgtaaatctc taatggcgta tccccacctt gaaatgaccg gctgctgatg
     8881 agcccgggaa gtccaaaaat atgatcgccg tgtaaatgtg taatgaaaat tttaccgatt
     8941 tttctcggac gaatagtcgt tcgcaaaatc tgcatttgcg tgccttcgcc acagtcgaac
     9001 aaccaaactt cattgcgctc gtctaaaagt ttcaatgcta tacttgtcac atttctatgt
     9061 tttgcaggaa cacctgcacc tgttcctaaa aattgtaatt ccataatcta cctgactttc
     9121 tttaagttcc tctttaattt tagggtaaaa agaagggata atcaaccgta agtcgagaat
     9181 gggttcaaat taaaaataac gttctaaagc gatagcgttt tctttgaaaa ttactataaa
     9241 aacagcagcg aacccgtttg agatcctctg ctgtttttta ttaatttgaa gatccagaac
     9301 tttcattgtc gttggaagtt tgcggatgtt tgtccttcca agtcttttgt gcagcttctt
     9361 tcgcatgatt ttcagcttct ttcgcatcat gcacatcttt ttcgacatct tcataatcca
     9421 agcgagtaat ttctccgcct aattccatca ttaccaattg attcagtggg cgattgtcct
     9481 cttcatcagc aatcaagatc agtcctgtag ctccttcacc gattttattt cctacaaagt
     9541 cgaacacggt ctgggcatct tttatttctt tggcatcttg tgtcgcaccg atcattcctc
     9601 cggcaaacca tcctaataaa atccctagcg gaccacctaa tacaccaacc aacattccga
     9661 ttaatccacc cgtagaagat ttgttattac cggtaaagtc gataaaatct tctattttga
     9721 attgatgtgt cccattagga tcatggctga caactgccat ctgttctcct ttaatcgaac
     9781 gaacagcatg taactttttg atttctgaaa atgcctgata tgcctggctt tctacttgaa
     9841 aatttaaaat gattactcgt ttgctcatta aaaacgcccc tttcatacct tcttgttatt
     9901 tattttacct ttaattgaaa aataagaaaa gaaaagcact ctttttttcc aataaaatag
     9961 ggctgtgaca aaagtcgtat cacagctcct ttttccgaat aaacggcgtt cttgaagctg
    10021 atcacttctg tcacaacctc ccttaaatct gaatctatat tttttggtat ttgtttttat
    10081 ttgcttgcct attcgacaaa ttcaaattca aactcaccga tacgtacaag gtcgccatct
    10141 ttcgcaccgc gtgcccgaag agcttcatcc acacccatac cacgtaattg acgagcaaaa
    10201 cgcatcactg tttcatcatg atcgaaattc gtcatttgga ataatttttc gatcttctca
    10261 ccagataaga tccacgttgc atctgaatca cgatcgattt ggaactcagg accttctgga
    10321 ttgaatccat agtgtacagt ttcttcttcc agttcttctt cgtacaatgg gaattctggc
    10381 gttacttcta acaaatctgc tgtagcattc aataacgcgt ccaatccttg tcgagtcact
    10441 ccagaaattg gaaatactgg gatgtcatca gcaaattcat cttctttttc cttgttcagc
    10501 tgttctttga atttcactag attttccggt gcatccggca tatccatttt gtttgccacg
    10561 atgatttgcg gacgctctag caagcgtaag ttataagtag ataattcttt gttgatggca
    10621 agatagtctt cataaggatc tcgtccttcc atcccactca tatcgatcac atgtaaaatt
    10681 actcgtgttc tttcgatatg acgaaggaat tgtgtaccca gcccaacacc ttgcgaagct
    10741 ccttcaatca agcctggcaa gtctgctgcg gcaaaacttc tgccatcact tgtagtaacc
    10801 attcctagat taggtacgag cgtcgtgaaa tgataagcgc cgatttttgg acgagcagat
    10861 gaaataacgg atagtaaagt cgatttcccg acagatggaa aacctacaag tccaacgtct
    10921 gccaatactt tcaattctag ttcgattttt cgctcttgtc ctggttcacc gttttcagca
    10981 atttccggtg caggattccg aggagaggca aaacggatat tccctcgtcc accgcgtcca
    11041 ccttttgcca caactagtgt ttgaccattt tcaattaaat ctcctaaaag agcaccagtc
    11101 tccgcatctc ggacagtggt tccttgtggt actttaacat aggtatcttc tgaaccacga
    11161 ccgtgcatcc ctttactcat cccattttca cctggctgcg ctttgaaatg gcgattgaac
    11221 cgaaaatcca tcaatgtacg taacccttca tcgacgatca agatgacatc gccgccacga
    11281 ccaccgtctc cgccagccgg tccgccgtca ggaacgtatt tttcgcgacg aaatgcaacc
    11341 attccgtctc cgcccttgcc agctttcaca tcgatcgtta cttgatctaa aaacatggac
    11401 ataattaagt cctcctatta ttcatttatt tatttgactg cctgaatttc cacaataaac
    11461 aaaagtctta cttattttat cggtgaaatc tgattttgtc tatcatttca gcaaaaagat
    11521 tgtttacctt cttctttttt tatcatttgg taaggtttcc aacctttttt ctgctaccaa
    11581 gtataatttt ttgacaaaat attctttgcg tagcagaata acagtgtatt aattgtatta
    11641 attgaggatg ccgtttcaca gcacccctaa taaaggagga acttttgata tgacagtaaa
    11701 agtaggtatt aacggatttg ggcgtattgg ccgtctggct ttccgccgca tcaaagaagt
    11761 ctcagatgat attgaagtag tagcaatcaa cgacttaaca agtccaacta tgttagcaca
    11821 attattgcaa tttgactcta ctcatggtac ttatcctggc acagttactg caacagaaga
    11881 ctcaatcgta gtggatggcg aagcaactcg tgtttatgca gaacccgacg caagcaaaat
    11941 cccttgggca aaagaaaacg gtgtagatat cgtactagaa tgtactggtt tttatacatc
    12001 tgaagaaaaa gcaaaagcgc atttagatgc tggtgtcaaa cgagtagtta tttctgcccc
    12061 agctggtgct atgaaaacca tcgtctataa cgtcaatgat gatacattag atgaaaacga
    12121 caaaatcatc tcagcaggtt catgtacaac aaactgttta gcacctatgg cttatttctt
    12181 aaataatgaa tttgggatcg aagttggtac aatgacaaca gttcatgcct acacttccac
    12241 acaaatgctc ttagatggac ctgtaaaagg cggtaatttg cgtgctgctc gttcagctgc
    12301 tgacaatact atcccacatt ctactggtgc tgcgaaagca atcggcttag ttatccctga
    12361 gctacaagga aaattacaag gacacgcaca acgtgttcca gtcgttgatg gttcattaac
    12421 tgaattggtt tcagtattga aaacaaaagt aactgctgat caagtaaacg aagcaatcaa
    12481 aaaacacaca gttgacaatc cttcattcgg gtatgatgac cgtcaaatcg tttctagcga
    12541 tgtcattgga acaactcaag gttcgatctt tgacccaacg caaacagaag taacaactgc
    12601 tggtgatttc caacttgtta aaactgttgc atggtatgac aatgagtatg gatttacttg
    12661 ccaaatgatt cgcttactag aaaaattcgc taacttgtaa tttgatagat caatcgataa
    12721 aagaagcctt tgactggatc cagtcaaagg cttctttctt ttcatcccct acttttaaac
    12781 tcgttcaatg aacatattgg cttaaaaatt gttggactac ttgctgatat ttttcaggat
    12841 ctgtcttgta tgcttccgca tgctcggctc cttttacaac atacttttct tttggtccct
    12901 tcgttgcacg atagacctta tctaacattt caaatggtac aaatgtatct tcgtctccat
    12961 gtataaagag cattgggcgc tggtttttct tcaattgttc cactgcattt gcttcaccga
    13021 aaaagtagcc agcacggact tttgtcacta gactcgttac ttgcataagc ggaaatgctg
    13081 gaagactaaa catatcgtct agctgataag caagctcatc atgaacggaa gaataaccgc
    13141 aatcttcaat gattgctttc acattatctg gtagtttttc tccgctagtc atcataactg
    13201 ttgctgctcc catgctgaca ccgtatagaa cgatttcttg cgattttcca ttgttttcta
    13261 gcactttgtt tatccactgt acatagtctt tacgctctgg ccatccaaat ccaatgtaat
    13321 ccccttcgct ttttccatgt cctcttgcat caggaacaag gacattgtaa cccatatcat
    13381 gaaacatctt tgcgtaattg gtcatcgttt cagcgtttcc catatagcca tgagccacaa
    13441 gagctgtttt ttcacttttc gtttcagcag gaagataaat cgctgataat ttcagaccgt
    13501 cttttgaagt gatggtccaa tcgcttcggt tttcttttga actaaaccat ttatgtgcat
    13561 ccgtttcttt ggatgtctgt gttgtaccag gtgtatcttc gtctaaaaag tctttctcag
    13621 aaggcacaac agcataatta taaaaataat tccctgcaaa cactaacgca acaatcagag
    13681 ctaaagcgac gcctaaaagg attttcatcc aaagtttcat aaatcatcca tctcatttct
    13741 cttttttcat ataaccttga attagtataa tcaaagaatc tctactatgc aatgttcatt
    13801 tttataac
//
LOCUS       DADGKS010000071        13732 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.072, whole genome shotgun sequence.
ACCESSION   DADGKS010000071 DADGKS010000000
VERSION     DADGKS010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.072"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(143..1345)
                     /locus_tag="JXV47_002280"
     CDS             complement(143..1345)
                     /locus_tag="JXV47_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAX1488297.1"
                     /translation="MKTKYPCVYQDKNGRFSYLVELGTDQVTGKRIQKKGTKDSLGKR
                     FSSAREAHKEVMRIKNEYMVVNGFANYDLTYKEFMEQSYVPHYKASVQKSTWSSRECG
                     LIQITEFFGDKKLREINVRDCENYRIWLLNDSGYSQAYSSLMYGMFRKSLDYAVTLQF
                     LNENISKRTKAIPKGKSIVPYWTKEEFEEVLAKIYKDDFYEHMCFLMIWLYYMTGVRV
                     SEGLALNWNDVDFKRKKLRVHHTLEMTNQKDFIRKPYTKTESGLRIISLDDDTIEVLK
                     KWKVIQKNHGVEQFILSYTDLPLYRSTVQRIIQRYAKLAKVPLIQGKGLRHSHVSYLI
                     NEFNADILVVSQRLGHSSPEITLKHYAHLWSRNDEGIAEQMTGNIKFTCATKSKVANF
                     NGNQAVKI"
     gene            complement(1348..1542)
                     /locus_tag="JXV47_002281"
     CDS             complement(1348..1542)
                     /locus_tag="JXV47_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAX1488298.1"
                     /translation="MKNTICRKDLEALGFKTHQATTIIRQAKTRMVNQGYPYYNNKRV
                     GVVPRQVIEEIIGVPLSQEE"
     gene            complement(1589..2437)
                     /locus_tag="JXV47_002282"
     CDS             complement(1589..2437)
                     /locus_tag="JXV47_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HAX1488299.1"
                     /translation="MQAYNQKIIETPTYIEIYDYEAIITPKRKTIENEVNLERKQKLA
                     WIYENDITLEKRKNYDELSAQGQYDSLKRKQKHYQSMRFEIARLVDTNFDNQTKFLTL
                     TFKENIQDIEYANNEFKKFIKRLNYDLYKTKKANLKYLATWEKQQRGAIHYHIILFDF
                     PFISFNRLTTIWGQGFVKINKIDVDSIENRGRYISKYFDKELELKEHKKKAFFKSRNL
                     KLPTVTKKMVKKPYDSTNQDILYTSEYIVRRPFFYNALALNELGSPEQVMDFQESTVH
                     YTKIKK"
     gene            complement(2642..2992)
                     /locus_tag="JXV47_002283"
     CDS             complement(2642..2992)
                     /locus_tag="JXV47_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488300.1"
                     /translation="MPIKITDLSLPKETLEKEYQVVNVTRWQKEGEILGWSYECILPK
                     LRYEKISVKVKSEHPVITPEELTQQGLAIITFTNLVIVPWGRSNGQFVSYGLSATADT
                     ATLIPRKQGTTTQN"
     gene            3587..4033
                     /locus_tag="JXV47_002284"
     CDS             3587..4033
                     /locus_tag="JXV47_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HAX1488301.1"
                     /translation="MKDYVVQITKEVLEESKTLNKLSSKAKEEAVTILSSGIIDYIEM
                     SGEIKYGEKDRIAKMVKESIKTFDVKQDLTFNDSYLIGKLINILGTDEDTELFLSSLS
                     MIFTDKHFSTRFGGEELVEIFQSMRPALIKLYREKTPDEFYDWFEK"
     gene            4657..5649
                     /locus_tag="JXV47_002285"
     CDS             4657..5649
                     /locus_tag="JXV47_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1488302.1"
                     /translation="MYWEEIELEKTLGPGGEIRAVQRDKKNISKWEKLKKQLRRDKWM
                     YLLLLPGIIMTFIFKYVPMYGAVIAFKDYNPMLGILESPWVGLDHFREFISSPNFTLL
                     LSNTLKISIYGLLLGFFPPIILALSLNQIINKKIKQKIQLILYAPNFISVVIIVGMLF
                     LFLSANGPINGLVEKVTGQPIMFMSNPAYFRTIYILSGIWQGIGWSSILYTATLAGVS
                     TDLYEAANIDGANILQKIWHIDLPALRPVMVISFILAAGGIMNVGYEKAYLMQTSMNI
                     PASEIISTYVYKVGLQSGDYAYSAAVGLFNMIINVVLLLIVNNITKRLNDGQGL"
     gene            5665..6549
                     /locus_tag="JXV47_002286"
     CDS             5665..6549
                     /locus_tag="JXV47_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAX1488303.1"
                     /translation="MNSALSKIDRQILWLNRVIVTFLVVITIVPLIYVLVASFMDPAT
                     LINKGISFNPKDWTIQGYQRVFADDSILRGFVNSLFYSFSFSLLTVFITMITAYPLSR
                     PNLAGKKIIMTFFVITMFVGGGLIPTYLLVKNLGMLDSVWAIIVPGAINVWNIILART
                     YFSALPKELSEAATIDGANDLQILFKVMLPLAKPIMFVLFLYAFVGQWNSYFDAMIYI
                     KDPDLQPLQLVLRNILIQNQPSQDMVGANTAMAEMKQIAELIKYATIVISSLPLIIMY
                     PFFQKYFDKGVLVGSVKG"
     gene            6598..8205
                     /locus_tag="JXV47_002287"
     CDS             6598..8205
                     /locus_tag="JXV47_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAX1488304.1"
                     /translation="MKAKWMLPIVFTSVLILGACGGSKEKSKSSPDYELENVSFPLKE
                     KVSLKMMSQSAPLAPNDPNDKLIFQRLEEETNLHIDWTNYSSDFAEKRNLDIASGDLP
                     DAIFNAAAGDYDLLNWAESGVIVPIEDLIEDYMPNLKKIFDENPEYRQMSTAPDGHIY
                     SMPWIEELGEGKESIHTVNGMAWINKEWLDNLGLEMPQTTDQLMTVLEAFKTQDPNGN
                     GEADEIPFSFINNGGNEDLKFLMGAFGLGDNDDHLVVDNDGQVQFTANKEGYKEAIKY
                     FNEMNNKGLIDKEAFEQDWNTYVAKGKEHKYGVYFTWDKANITGADDSYDVLPVLAGP
                     DGTKHVTRTNGMGFSRDRFVITSANKNLELTARWIDKMYEPLQSVQNNWGTYGDEAQA
                     NIFELKDGMLKHLPLEGTAPGELRQKTEAGGPLAVLDSYYGTVTTMPDDAKWRLDLMH
                     DTYLPYITEDNIYPRVFLEKEETDRLAKIETDMWDYIYRKRAEWITGGKIDEEWEEYL
                     AELERVGLEEWIQIKQTGYDNFLKGAQ"
     gene            8206..9690
                     /locus_tag="JXV47_002288"
     CDS             8206..9690
                     /locus_tag="JXV47_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016621147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HAX1488305.1"
                     /translation="MLVEETAILDKANRFIEMMRGKVNPQYRQNYHFSAPIGWINDPN
                     GFIYYKGHYHLFYQYYPYDSRWGPMHWGHARSSDLVHWEDLPVALAPDQPYDSGGCFS
                     GSAIERDGKLYLFYTGCQEIDGISHQHQCLAVSEDGIHFSKYSGNPVVAEKQLGENGL
                     IQEFRDPKVIVHNDGYYMVVATKSTQSTGRIVMFQSSDLYTWHFYSVLLEGTSEQGIM
                     WECPDLFHLDGRDVLIMSPIQIKKNGLEYHNISSTMACIGEVNWETGQMIVDNFHEMD
                     FGMDFYAPQTTRDPNGGRVMIAWMQMWDRTLPTHELGHLWAGSMSLPRELRVKKNRLV
                     QKPISTVYSHLVYQQGSENIAVTDTSVVFRNALSDSSYLHLVADLEKAEVFTIELLRS
                     KTDCLKLAYDTATQVFELDRQKLGRELTGAEEDPLNVRKVEVPLIDNQLVLEIFRDTS
                     SIEVFINGLEVMTATFYELEKARDILFHSIGESRIQAFETASVK"
     gene            9867..10859
                     /locus_tag="JXV47_002289"
     CDS             9867..10859
                     /locus_tag="JXV47_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005230454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAX1488306.1"
                     /translation="MKATMKDVAKLAGVGVGTVSRVLNNGSVKASTREKVEAAMTELN
                     YQPDFYARGLKMKHTNTVALILPTVWHPFFGEFAYHVETALERQNYKLYLCNSSGNSE
                     KEQEYIQMVSQNKVDGIIGITYSDIDEYISSNLPFVSIDRYFTEEVIYVTADNAAGGR
                     LAANELYRRGCQNVAYIGGYQETPNETKSRRKYFEIECRQLGISYKALDMLEPLDHLS
                     ERVTNFLLENPDIDGIFTINDPMALAVIDMLEKIGKNVPEDVQVIGFDGQKMTEGDPY
                     LVSTIAQPTKQMAEVAVAKLIAVINGETVEKRTVLPIEFGEGDTTKPLVRNDFA"
     gene            10911..11780
                     /locus_tag="JXV47_002290"
     CDS             10911..11780
                     /locus_tag="JXV47_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAX1488307.1"
                     /translation="MLYGGIEAGGTKFVCGIGNEQLQVIERKSFPTTTPEETMEQVFD
                     FFDKYKGNIASIGVGAFGPIDIQIESRTYGYITNTPKLAWQNYHFVGALENALSVPIY
                     WTTDVNAACYGEYMAGYGKGKNSVLYYTVGTGVGGGAVVDGKIVAGFSHPEMGHMLLQ
                     RHNEDQFEGICPFHHDCLEGLASGPAIEKRFGRKAQTISFDHPYWTIEADYLAQCVYN
                     TTLLYAPEVIILGGGVMKQPQLLELIRQSFKEKMGSYVDTPTLEEYLLTPRLADNAGL
                     IGCLALAIKKLNH"
     gene            complement(12200..13693)
                     /gene="guaA"
                     /locus_tag="JXV47_002291"
     CDS             complement(12200..13693)
                     /gene="guaA"
                     /locus_tag="JXV47_002291"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAX1488308.1"
                     /translation="MITRRIREFGVFSELMSHRITAEEVKAMNPKGIILSGGPNSVYD
                     EKAFGIDEKIFDLGIPVLGICYGMQLITYKLGGKVKPAKNREYGKAELEITSAEAALF
                     QNTPEKQTVWMSHGDLVTQAPTDFDVVATSKDCPIASIQNAERKMYGIQFHAEVRHSE
                     YGNDLLRHFTLDVCQCTGDWTMDNFIDMEIAKIREQVGDKKVLLGLSGGVDSSVVGVL
                     LQKAIGDQLTCIFVDHVLLRKGEAEQVMESLGGKFGLNIIKVDAKERFLSKLAGVSDP
                     EEKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQGTLYTDVIESGTETAQTIKSHHNVG
                     GLPEDMQFKLIEPLNTLFKDEVRELGTQLGMPDSIVWRQPFPGPGLGIRVLGELTEEK
                     LEIVRESDAILREEIANAGLDRDIWQYFTVLPGIRSVGVMGDGRTYDYTVGIRAVTSI
                     DGMTADFARIPWEVLQKISVRIVNEVAHVNRIVYDITSKPPATVEWE"
BASE COUNT         4214 a         2322 c         2832 g         4364 t
ORIGIN      
        1 ttgaaaaacg ttgatttatc ggcattcccc atccatatta tatttacgtc ttattcccac
       61 tcaatatgag tagcctcgta aagaagctat tatatcagtg ctttttcagc ctattcctca
      121 ttttggtagg gaaatggtag ggttagattt ttactgcttg atttccatta aagtttgcaa
      181 ctttagattt tgttgcacag gtaaatttaa tgtttcctgt catttgttct gcaattcctt
      241 catcattacg gctccataga tgagcgtagt gctttaaagt gatttcaggg ctagaatggc
      301 ctaaccgttg cgacacgacc agaatgtctg cgttaaactc attgattagg tagctaacat
      361 gagaatgacg taatcctttt ccttgtatta ggggtacctt agctagtttg gcataacgct
      421 gaataattcg ttgaacagtt gaacgataga gtgggaggtc agtgtagcta agaataaatt
      481 gttctacacc atgatttttt tgaataactt tccacttttt tagcacttca attgtatcat
      541 cgtccagaga aatgatccgc aagccgcttt cagtttttgt gtaaggtttc cgaataaaat
      601 ctttttgatt tgtcatttcc aaggtgtgat gaaccctcaa ctttttacgt ttgaagtcca
      661 cgtcattcca attaagtgct aatccttcgc ttacacgaac accagtcatg taatatagcc
      721 agatcattaa aaaacacata tgttcgtaga aatcatcttt ataaattttt gccaaaactt
      781 cttcaaattc ttcttttgtc cagtaaggaa cgattgattt tccttttgga attgcttttg
      841 ttcttttgga aatattctca ttcagaaatt gcagggtgac cgcatagtct aatgatttac
      901 gaaacatacc gtacataagt gaactgtatg cttgtgagta tccgctatcg ttcaataacc
      961 aaattcgata attttcacaa tctcgcacat tgatttcacg aagcttctta tcaccgaaaa
     1021 attcagtaat ctgaatcaat ccacactcac gagaactcca agtacttttt tgtacgctag
     1081 ctttgtagtg tggaacgtaa gactgctcca taaattcttt gtaagttaaa tcataattcg
     1141 caaatccatt tacaaccatg tattcatttt ttatacgcat gacttctttg tgtgcttcac
     1201 gagctgatga gaatcgtttt cctagagaat cttttgttcc tttcttctgg atcctctttc
     1261 cagtcacttg atctgttcct aactcaacta gataagaaaa gcgaccattt ttatcttgat
     1321 acacacaagg gtattttgtt ttcatagtta ttcctcctgt gaaagaggaa cacctataat
     1381 ttcttcaatt acttgtcggg gtactacccc aactctttta ttattataat atggatatcc
     1441 ctgatttacc attcttgttt ttgcttgtcg gattattgtg gtagcttgat gtgttttaaa
     1501 tcctagagcc tctaaatctt ttcgacaaat tgtatttttc attgtataaa ctcactttca
     1561 aagaaaacac tatcattggg taatagtgtt atttctttat ttttgtataa tgaacggtac
     1621 tttcttgaaa atccatcact tgttcaggac ttcccaactc atttaaagct aaagcattgt
     1681 aaaaaaatgg acgtctaact atatattcgc ttgtatatag tatatcttga ttcgtggaat
     1741 catagggttt ctttaccatc tttttggtga cagttggtag tttgagattc cgggacttga
     1801 aaaaagcttt tttcttatgc tctttcaatt ccagctcttt atcgaaatat ttgctgatat
     1861 agcgcccgcg attttcgata ctgtctacat cgatcttgtt gatcttaacg aaaccctgac
     1921 cccaaatcgt agttaaccgg ttaaatgaga taaaggggaa atcaaacaag ataatatggt
     1981 agtggattgc accgcgttgc tgcttttccc acgtggcgag atactttaaa tttgcttttt
     2041 tagttttata gaggtcataa ttcagtcgtt tgataaattt tttaaattca ttatttgcat
     2101 actcaatgtc ttgaatgttt tctttgaaag tgagagttaa aaatttcgtt tgattgtcaa
     2161 aattcgtgtc tacaaggcgg gcaatctcaa atcgcatact ttgataatgt ttctgtttgc
     2221 gttttaaact gtcatattgt ccttgagcgg ataattcatc atagtttttt cttttttcaa
     2281 gagtaatatc attttcataa atccaagcta atttttgttt tcgttccaga tttacttcgt
     2341 tttcgatcgt tttacgtttg ggagtaatga ttgcttcata atcataaatt tcaatatacg
     2401 tgggagtttc aatgattttc tgattataag cttgcaaaaa tcatcactcc ttgttgcgta
     2461 ttcgattgtc aaagaaccag tcattttctc ctgatgttga tctataaatc aagttaaggg
     2521 ggaaggcctg cgtagcagcc cttctagcct atggggtgtt gggcggtctt aacggacaga
     2581 aacggctctg tgggcgctgc cccgccgttt cgtcctaacc acccaacact ccatagtata
     2641 gttagttttg tgtagtggta ccttgttttc tgggaatcaa agttgccgta tcagcggttg
     2701 ccgataaccc ataactgaca aattgtccat tcgagcgtcc ccaaggtaca atcaccaaat
     2761 tggtaaatgt aattatggct aaaccttgtt gggtaagttc ttccggcgtg atcacaggat
     2821 gttcagattt gactttgaca ctgatttttt cgtagcgaag ttttggtagg atacattcgt
     2881 agctccaacc tagaatttcg ccctcctttt gccagcgagt gacattgacg acttggtatt
     2941 ctttttcgag tgtttctttt ggtaaactga gatcggtaat ttttattggc atcacaattc
     3001 tcctttttta tacgaaagtt tatacgattt gattaaaaaa tatagatggc catctacgac
     3061 ttgtattata tacgagaact tatacgtagt caagagattt tctaaaaaaa tatatacgat
     3121 tttttatacg agtgttataa tgaaaaaaat gataaggagg aatttgaata tgtttggttt
     3181 agtacaacct aataaagtga aggtgggcca acgaatcaaa gaaataaaag acggaatgtc
     3241 tctctctttt acagaattag ggaatcgatt aggtttaaaa aagccgacga tcagttccta
     3301 cgttcaaggc tatgcgttgg ctcctaagag tgtgatcaac caattatcta gtatcagcgg
     3361 aaaacctgtc ggctggtttt attttgggca tgtggaagaa tatatccgag agtatttgtt
     3421 tctcattggt cagaaaaaaa tagtggacga ttatcctgaa atcattgaga aaataaagca
     3481 agaattttat acgggcgagt tcaaaaatcc tgcttgggag aatgagctag gctatccttt
     3541 ggaggaattt atccaagaat gttttgtaga atattcgagt gaaatcatga aggactatgt
     3601 cgtacagatt acgaaagagg tacttgaaga atccaaaacg ctaaacaaac tatcatcaaa
     3661 agcaaaagaa gaagctgtca cgattctttc atctgggatc attgactata tcgagatgag
     3721 tggtgagatc aagtatggag agaaagatcg cattgcgaaa atggtgaaag aatcaataaa
     3781 aacctttgat gtgaaacaag acctgacatt taatgattcc tatttgattg gaaagttgat
     3841 caatattctt ggtacagatg aagatacgga gctgtttctt tcttctttat caatgatatt
     3901 tactgataag catttttcca ctcgatttgg tggggaagaa ttagtcgaaa tatttcaatc
     3961 gatgcgacca gcgttaatca aactctatcg ggagaaaaca ccagatgaat tttatgattg
     4021 gtttgagaag taaaataaga aaagtggctt agattacaag ttggtgaaaa aatttttttc
     4081 agcataacat cagtaatcta taaaggggtt gttgattata ctgtagaagt taagtactca
     4141 agagattttt tgtacgtaaa caaagcaaaa aagggtgcag tttcactaga aaatgtactc
     4201 ttttttgtga tttttcttag ttatagagtt tttttgaaac tttaaaaatg agaaaacata
     4261 ttgattttaa agagtgtaga catagcttct tttgctaaat agattaaact tactggtgag
     4321 tggtcttgaa catactttta aatcacattt tactgagttt tattggattt tataattcat
     4381 tggaaacctc gtacttaatc tgtttttatc tatcgactag aatctgtata tattccagct
     4441 atcaatgagg ccgcagaaaa gggtgcttaa aaataatctg ttgtttaaaa tattattatc
     4501 agaatactta gatacaaaat tctggcacaa agtaaaaaaa atattgactt aaaaaaatgg
     4561 atatggtaat ctataaacga aaatagtggt aacgtttcca aaatgcatct tcgttaaatt
     4621 tttatttttt taaacgaaaa tggaaacgtt tctaaaatgt attgggagga gattgaattg
     4681 gaaaagacat tgggaccagg tggtgagata agggcggtac aacgggataa aaaaaatatt
     4741 tcgaagtggg aaaaattaaa gaaacagttg cggcgtgata agtggatgta cttgttgctc
     4801 ttaccaggta tcatcatgac gtttatcttt aagtatgtgc caatgtacgg tgctgtgatt
     4861 gcatttaaag actataatcc tatgctagga attttggaaa gtccttgggt aggactagat
     4921 cactttaggg aatttatcag ttcaccaaat tttacgcttt tgctgagcaa cacattaaaa
     4981 attagtattt atggtttatt gttaggtttt tttccaccaa ttattttagc actgagcttg
     5041 aatcaaatta tcaataaaaa aataaaacag aaaatccagt tgattctata tgcgccgaat
     5101 tttatctcag tagttattat tgtggggatg ctgtttttgt tcctatccgc aaatggacct
     5161 attaatgggt tagtagaaaa ggttacgggg caaccaatta tgttcatgtc taatccagct
     5221 tatttcagaa cgatttatat tttatcggga atttggcaag gaatcggctg gtcatccatt
     5281 ctttacaccg caacgctggc gggagtcagt accgatttat atgaggcagc aaatatcgat
     5341 ggggcaaata ttttacaaaa gatttggcat atcgatttgc ctgcattgag gcctgtgatg
     5401 gtgatcagct tcatcttggc cgccggcggt attatgaatg taggatatga aaaagcctac
     5461 ttgatgcaaa cttcaatgaa catccctgcc tcagaaatca tttccactta tgtatacaaa
     5521 gtcggcttgc aatcaggtga ttatgcctac tctgctgctg ttggtctgtt caatatgatt
     5581 attaatgtcg ttttattact gattgtcaac aatataacca agcggctaaa cgatggtcaa
     5641 ggcttgtaat gaaaggagaa aattatgaat agtgctttat caaaaatcga ccgtcaaatc
     5701 ttatggttga atcgagtgat tgtaactttt ttagtcgtca tcaccattgt tccgctgatt
     5761 tatgtactgg tagcttcttt tatggaccca gctactttga tcaataaagg tataagcttc
     5821 aatccgaaag attggacaat acagggatat caacgggtat ttgcagatga ttccatttta
     5881 cgcggttttg taaattcgtt gttttactct tttagcttca gcttattgac tgtatttatt
     5941 acgatgatca ctgcgtatcc tttgtctcga cctaacttgg cggggaaaaa gattattatg
     6001 actttttttg tcattacaat gttcgtgggt ggtggcttga tacctaccta tttattggta
     6061 aagaacttgg gcatgttaga tagtgtatgg gcgattatcg taccaggtgc tataaatgtg
     6121 tggaatatta tcttagcccg tacctatttt agtgctttgc caaaagaact ttctgaagct
     6181 gctactatcg atggcgccaa tgacttgcaa atactgttca aagtcatgct tccattagcg
     6241 aaaccaatta tgttcgtatt gtttttatat gcctttgttg ggcaatggaa ctcatacttt
     6301 gatgccatga tttacatcaa agatcccgac ttacagccgt tgcaactcgt attaagaaat
     6361 attttgatcc aaaaccaacc ttcacaagac atggtgggag ccaatactgc catggcagaa
     6421 atgaaacaaa ttgctgagtt gatcaaatac gcaacgatcg tcatttctag tctgccatta
     6481 atcataatgt atcctttctt ccaaaaatat tttgataaag gtgttttagt tggttctgtt
     6541 aaagggtaag tattgttcac tatttgtatg aataaaaatt ataaaggaga ttttaagatg
     6601 aaagcaaaat ggatgctgcc aatcgttttt acttccgtac taattttggg ggcttgtgga
     6661 ggctcaaaag aaaagagtaa atcaagccct gattatgaac tagaaaatgt ctcttttcca
     6721 ttgaaagaaa aagtatcttt aaaaatgatg tctcaaagtg cccctttggc tcccaatgat
     6781 cctaatgaca aattgatttt ccaacgatta gaagaagaga ccaatctcca tattgattgg
     6841 acaaactaca gtagtgattt tgccgaaaaa agaaatttgg atatcgctag tggtgattta
     6901 ccagatgcca tcttcaacgc cgctgcaggt gactatgatt tattaaactg ggcggaaagt
     6961 ggcgttattg taccgattga agatttgatc gaagattata tgccaaatct gaagaaaatt
     7021 tttgatgaaa accccgaata ccgacaaatg tctactgcac ctgatggtca catttactct
     7081 atgccttgga ttgaagaatt aggcgaagga aaagagtcga ttcatacagt aaatgggatg
     7141 gcttggatca acaaggagtg gttggataat ttgggtcttg aaatgccgca aaccactgat
     7201 cagttgatga ctgtgttgga ggctttcaag acgcaagatc caaatggtaa tggtgaagca
     7261 gatgaaattc cttttagctt tattaacaat ggaggaaacg aagacttaaa atttttaatg
     7321 ggggcattcg gtctaggtga taatgatgac cacttagtcg ttgataacga tggtcaggta
     7381 caatttactg ctaacaaaga agggtataaa gaagccatca aatatttcaa tgaaatgaat
     7441 aataaaggtc ttattgataa agaggctttc gaacaagatt ggaatacgta tgttgccaaa
     7501 gggaaagaac ataagtatgg cgtgtacttt acttgggata aagcaaatat cacgggtgca
     7561 gatgatagtt atgacgtctt gccagtctta gcgggaccag atggaacgaa acatgttact
     7621 cgtacgaatg gcatgggttt ctcaagagat cgtttcgtaa ttactagtgc gaataaaaac
     7681 ttggaactta cagctaggtg gatagataaa atgtatgaac cgttacagtc tgtccaaaat
     7741 aactggggaa cctacggtga tgaagcacag gcgaatattt ttgaattaaa ggatggtatg
     7801 ttaaaacatt tgcctttaga ggggacagca ccgggggaac taagacaaaa aaccgaagct
     7861 ggaggaccat tagcagttct tgattcttat tacggcacag tcactactat gccagatgat
     7921 gcgaagtggc gtttagattt gatgcatgac acgtatttgc catatattac agaagacaat
     7981 atctatccac gtgtcttttt agaaaaagaa gaaacagatc gattagcaaa aatcgaaacg
     8041 gatatgtggg attacatcta tcgcaaaaga gcagagtgga tcaccggcgg taaaatcgat
     8101 gaagaatggg aagaatacct tgctgaattg gaacgtgtag gtttggaaga atggattcaa
     8161 ataaaacaaa ctggctatga taattttttg aagggagcac aataagtgtt agtagaagaa
     8221 acggcgattt tggataaagc aaatcgattt attgaaatga tgcgaggaaa agttaaccct
     8281 cagtatcgac aaaactatca tttttccgca cccatcgggt ggataaatga ccccaatggg
     8341 tttatatatt acaaagggca ttaccatctc ttctatcaat actatcctta cgatagtcga
     8401 tgggggccca tgcattgggg gcatgcgcgc agtagtgatt tggtccattg ggaagatcta
     8461 ccagtagcgt tagccccaga tcaaccttat gacagcggcg ggtgtttctc aggaagtgca
     8521 attgaaagag acggaaaact atatttattt tatacaggct gtcaagaaat tgatggtatt
     8581 agccatcagc atcaatgttt ggcggtctct gaagatggta ttcattttag caaatacagt
     8641 ggtaatcctg tggtagcaga aaaacagcta ggtgaaaatg ggctaataca agaatttcgt
     8701 gatcctaaag taattgttca caacgatggt tactatatgg tagtagctac taaatctaca
     8761 cagtctactg gtagaatagt gatgtttcaa tcgtcagatt tgtatacttg gcacttttac
     8821 tctgtgctgc tagaagggac ttcagagcaa ggaataatgt gggaatgtcc tgatttattc
     8881 catttagacg gacgagatgt cttaatcatg tctccgatac aaatcaagaa gaacggactg
     8941 gaatatcata atatcagttc taccatggct tgtattggtg aggtaaactg ggaaacaggt
     9001 cagatgatag ttgataattt ccatgaaatg gattttggaa tggattttta tgcaccacaa
     9061 acaacaagag atcctaatgg tggacgggtg atgattgctt ggatgcagat gtgggatcgt
     9121 acattgccta cacatgagtt aggccatctt tgggcaggct ctatgagttt gccccgagag
     9181 ttaagagtga aaaaaaatcg attggtacaa aaacccatct caactgtata tagtcattta
     9241 gtttatcaac aaggcagtga aaatattgca gtgactgaca catcagtcgt atttcgaaac
     9301 gcgctgtctg attcttcata tttacatcta gtcgcagatt tggagaaagc tgaagttttt
     9361 acaattgaat tactgcggtc taagacggat tgtctcaaac tagcctatga cactgctaca
     9421 caggtttttg aattggatcg tcagaaacta ggaagagagc ttacaggggc ggaagaagac
     9481 cctctgaatg tacgaaaagt tgaagtacct ttgattgata atcagctcgt tcttgagatt
     9541 tttagagata cctcatcaat tgaagtcttt attaatgggt tagaagttat gacggctact
     9601 ttctatgagc tggaaaaagc tcgagatatc ttgtttcatt cgatcggaga aagtcgtatt
     9661 caagcttttg aaacagcgag tgtgaaataa atgtttgatt gcttaggcga tgaatcaatt
     9721 atttaatagg ttttgaagga taatgttttt agaaaagaac agatagctag atttcccatg
     9781 gatttgctat tagtattttg aaaaaattag taatttatga caaaattcat tatactaaac
     9841 ttgtgcagaa atgtgaggga tcaactatga aagcaacaat gaaagatgtc gcaaaattag
     9901 caggtgttgg agtaggaact gtttcccggg tattgaataa cggttctgtt aaagcttcta
     9961 ctagagaaaa agttgaagca gcaatgacag agttaaacta tcaaccagat ttttatgccc
    10021 gggggttaaa gatgaagcat acgaacacgg ttgctttgat tctacccacg gtatggcatc
    10081 cattttttgg cgaatttgcc taccatgtag aaacagcatt agaaagacaa aactacaagc
    10141 tttatttgtg taactccagt ggtaatagtg aaaaagaaca agaatatatc cagatggtca
    10201 gccaaaataa agtagacggc atcattggaa ttacttattc agatatcgat gaatacattt
    10261 cgagtaatct gccttttgtt agtattgacc gttatttcac tgaagaggtg atttatgtga
    10321 ccgctgacaa tgcggccggt ggacgtttgg ctgcaaatga actttatcgc cgaggatgtc
    10381 agaatgtagc atatatcggt gggtaccaag aaacaccgaa tgaaacgaag agtcgtcgaa
    10441 aatattttga aatcgagtgc cgtcaactgg ggatttccta taaagcgtta gatatgttag
    10501 aacctttaga ccatctctca gaacgtgtaa caaatttttt gttagagaat cccgatatcg
    10561 atgggatttt tacgatcaac gatccaatgg cattagctgt cattgatatg cttgaaaaaa
    10621 tagggaaaaa cgtaccagag gatgtccaag ttatcggatt tgatggtcaa aagatgacag
    10681 aaggagatcc ttatctagtc tcaacgattg cccaacctac aaagcaaatg gcggaagtgg
    10741 cagtggcaaa attaattgct gtcattaatg gagagacagt agaaaaacgt accgtattgc
    10801 cgattgaatt tggcgaaggt gacacaacga aacctttagt gagaaacgat tttgcttagt
    10861 gcaaatacgt ttcttttttt gaaaatgagt gaatgaaagg tgtagataaa atgttatatg
    10921 gtggaataga agccggtgga acaaagtttg tctgtgggat tggtaatgaa caattacaag
    10981 tgatagaacg gaaaagtttt cctaccacaa caccagaaga aacgatggag caagtgtttg
    11041 atttctttga taagtacaaa ggaaatatcg catcaattgg tgtaggagca tttgggccta
    11101 ttgatattca aatcgaatca agaacttacg gatatatcac caacacaccg aagttagctt
    11161 ggcaaaatta tcattttgta ggagctttgg aaaacgcctt gtcggttccc atctattgga
    11221 ctaccgatgt aaatgctgct tgttatggag aatatatggc agggtatgga aaaggtaaaa
    11281 atagtgttct gtattacacc gttggtacag gtgttggtgg tggtgctgta gtggatggga
    11341 aaatagtcgc aggttttagt catcctgaaa tgggacatat gctcttacaa cgtcataatg
    11401 aagatcaatt tgaaggaatc tgtccttttc atcatgattg tttggaaggg ttagcatcag
    11461 gacctgcgat tgaaaaacgc tttggaagaa aagcccagac tatctcattt gatcatcctt
    11521 attggacgat tgaggcagat tatcttgctc agtgtgtgta taacacaacg ttactatatg
    11581 caccggaagt aataatttta ggcgggggtg taatgaaaca gccgcaacta ctcgagttga
    11641 ttcgccaatc gtttaaagaa aaaatgggtt cctacgtgga tacgcctact ctcgaagaat
    11701 atctactaac tccaaggctt gctgacaatg cgggcttgat tggctgccta gctttagcaa
    11761 taaagaaact caatcattag aatagtattt attagaacta ttcataacat accggaagtt
    11821 taaaagggta ttctgaaact taaatagtct caattcattc ttctttcttg agaatctgag
    11881 tagagacttt tattctgttt caaattaata taattacgaa atgatattga gtacaagaaa
    11941 gttcttttta ccagatcttt taaatcgaaa aatctgatat atatatttat agtactaaaa
    12001 atctgattag ataaaaagct aattcaatag gaaaataaag gtagtgaata aaagcaaagc
    12061 ccttgttagt agttaatcta acaagggctt tggtagggaa aatggtagga aaccatctta
    12121 ttttttacga aaatcaggaa ctttagtaat tgaataatgt tgatttatag gtattcctca
    12181 tccatattat gttggctctt tattcccact ccactgttgc aggtggtttg ctggtaatat
    12241 catacacgat acggttaacg tgtgcgactt catttacgat acggacactg attttttgca
    12301 agacttccca agggatacgg gcaaagtcag cggtcatgcc gtcaatagaa gtgacagcac
    12361 ggatacctac agtgtagtca tacgtacggc catctcccat aaccccaaca gagcgaatgc
    12421 ctggtaggac ggtgaagtat tgccagatgt cgcgatctaa accggcattg gcgatttctt
    12481 cgcgcaagat agcgtctgat tcacggacga tttctaattt ttcttctgtc aattcaccaa
    12541 ggacacgaat acctaagcct ggtccaggga atggttggcg ccaaacgatg ctgtcaggca
    12601 tgcctaattg ggtacctaat tcacgtactt cgtctttgaa caatgtgttc aatggctcga
    12661 tcagcttgaa ttgcatgtct tcaggtaatc cacctacatt gtgatgtgat ttgatggttt
    12721 gggcagtttc agttcctgat tcgatcacat cggtataaag ggttccttgt gcaaggaaag
    12781 aaacgccttc ttcaccggca agtttggttg cttcatcatc gaagacatat acaaattcat
    12841 ttccaatgat tttacgtttt tcttctggat cagacacgcc agcaagtttt gataagaaac
    12901 gttctttggc atcgactttt ataatgttca agccaaattt tccgccaaga ctttccataa
    12961 cttgttctgc ttcaccttta cgcaacaata cgtgatcaac gaagatacat gttaattgat
    13021 cgccgatcgc tttttgtaaa agaacaccaa caacagagga atctactccg cctgaaaggc
    13081 ctaataaaac ttttttgtca ccgacttgtt cacgaatttt tgcgatctcc atgtcgatga
    13141 agttatccat tgtccagtca ccagtacatt ggcagacatc tagtgtaaaa tggcgcaaca
    13201 agtcatttcc atattcggaa tggcgaactt ctgcatggaa ttggattccg tacattttgc
    13261 gttctgcatt ttggatcgat gcgatggggc aatctttgct ggtagcaacg acatcgaaat
    13321 cagtcggtgc ttgggtaact aggtcaccat gactcatcca aacggtttgt ttttcaggag
    13381 tgttttggaa aagggccgct tctgcagaag tgatttccaa ttctgctttt ccgtattcac
    13441 ggtttttggc tggtttaact tttccgccta atttataagt aatcaactgc ataccgtaac
    13501 agattcctaa aactgggatc cccaaatcaa aaatcttttc atcaatacca aaggccttct
    13561 catcataaac actgtttggt ccgccagaaa ggatgattcc tttagggttc attgccttta
    13621 cttcttctgc ggtaatgcgg tggctcatca actctgagaa aacaccgaac tcacgaatac
    13681 ggcgagtgat cagttggtta tactgactac cgtaatcaag tacgataatt tt
//
LOCUS       DADGKS010000072        13696 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.073, whole genome shotgun sequence.
ACCESSION   DADGKS010000072 DADGKS010000000
VERSION     DADGKS010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13696
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.073"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            496..1098
                     /locus_tag="JXV47_002292"
     CDS             496..1098
                     /locus_tag="JXV47_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAX1488309.1"
                     /translation="MAKIGYARVSSKEQNLDRQLKALEGVSKVFSDKLSGQSVERPQL
                     QAMLNYIREGDIVVVTELDRLGRNNKELTELMNQIQIKGATLEVLNLPSMNGIEDENL
                     RRLINNLVIELYKYQAESERKRIKERQAQGIEIAKKKGKFKGRQPKFKENDPRLQHAF
                     DLFLNGCSDKEVEEQTGINRRTFRRYRSRYNVTVDQRKKQ"
     gene            1114..1791
                     /locus_tag="JXV47_002293"
                     /pseudo
     CDS             1114..1791
                     /locus_tag="JXV47_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            2303..2599
                     /locus_tag="JXV47_002294"
     CDS             2303..2599
                     /locus_tag="JXV47_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="HAX1488310.1"
                     /translation="MSKGFLEPALFNQERNVLDSEIKNLTTEKTNLVTNSASGVLRAN
                     EIKDLINYVSADNFNGDYTEELFEEFVVNIIVNSRDELTFNLKCGLSLKEKVVR"
     gene            2600..3016
                     /locus_tag="JXV47_002295"
     CDS             2600..3016
                     /locus_tag="JXV47_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HAX1488311.1"
                     /translation="MAYIPYGYKIQDGVVTVDEKAAGQVKVFFEKYISGLSLTVAGEQ
                     AGIEKTHSVMGRILKNVNYLGNDTYPAIIDKEIFDKAEEVRDKRAKDLGRVVELAAFT
                     SPPPKERFKMKKADNKMPVDPFERAEYLYSLIESEE"
     gene            3036..4580
                     /locus_tag="JXV47_002296"
     CDS             3036..4580
                     /locus_tag="JXV47_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAX1488312.1"
                     /translation="MVIPARKRVGSTAAKEKIKKLRVAAYCRVSTETEEQNSSYEVQV
                     SHYTEFIKKNNEWEFAGIFADDGISGTNTKKRDEFNRMIAECMDGNIDMVITKSISRF
                     ARNTLDCLQYIRQLKDKNISVYFEKENINTTDAKGEVLLTIMASLAQQESQSLSQNVK
                     LGLQYRYQQGKVQVNHKRFMGYTKDEDGNLTIVPEEAEIIKRIYREYLEGQSLVGIGR
                     ALEKDGILTAAGKPRWRPESVKKILQNEKYIGDALLQKTVTVDFLTKKRVKNEGHVPQ
                     YYVENSHEAIIPKELFLQAQEEIHRRSNIYTGEGKNKRIYSSKYALSAITFCGDCGDI
                     YRRVYWNIHGRKEFVWRCVTRIEQGPEVCKNRTVKEDELYGAVMTAINKLLAGGNNMI
                     KTLEENIHAVIGETTEYQISEINNSLEEKQKELIKLANKGQDYDHLADEIDELRDKRQ
                     ILLVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEGHFVIAFKS
                     GIEMEI"
     gene            4723..4947
                     /locus_tag="JXV47_002297"
     CDS             4723..4947
                     /locus_tag="JXV47_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1488313.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            4962..5831
                     /locus_tag="JXV47_002298"
     CDS             4962..5831
                     /locus_tag="JXV47_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HAX1488314.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            5812..6546
                     /locus_tag="JXV47_002299"
     CDS             5812..6546
                     /locus_tag="JXV47_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008766909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAX1488315.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            6579..7487
                     /locus_tag="JXV47_002300"
     CDS             6579..7487
                     /locus_tag="JXV47_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HAX1488316.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            7484..8026
                     /gene="sat4"
                     /locus_tag="JXV47_002301"
     CDS             7484..8026
                     /gene="sat4"
                     /locus_tag="JXV47_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HAX1488317.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            8119..8913
                     /locus_tag="JXV47_002302"
                     /note="aph(3')-IIIa"
     CDS             8119..8913
                     /locus_tag="JXV47_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HAX1488318.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            complement(9021..9209)
                     /locus_tag="JXV47_002303"
                     /pseudo
     CDS             complement(9021..9209)
                     /locus_tag="JXV47_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913594.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            9189..9761
                     /locus_tag="JXV47_002304"
     CDS             9189..9761
                     /locus_tag="JXV47_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAX1488319.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIEPISLGFYEQNWYLIGFAG"
     gene            10101..10955
                     /locus_tag="JXV47_002305"
     CDS             10101..10955
                     /locus_tag="JXV47_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAX1488320.1"
                     /translation="MEKEKLKILEELRRILNNKNEAIIILNNYFKGGVGKSKLSTMFA
                     YLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKNGNLASSIIHLTDNL
                     DLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIIIDTVPTPSVYTNNAI
                     VASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFVPYLVDTDSATIKSN
                     LEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVLSMYENVFFEMIERI
                     IQLENEKE"
     gene            11054..11263
                     /locus_tag="JXV47_002306"
     CDS             11054..11263
                     /locus_tag="JXV47_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HAX1488321.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
     gene            11280..11552
                     /locus_tag="JXV47_002307"
     CDS             11280..11552
                     /locus_tag="JXV47_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAX1488322.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            11554..12417
                     /locus_tag="JXV47_002308"
     CDS             11554..12417
                     /locus_tag="JXV47_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin zeta"
                     /protein_id="HAX1488323.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(12680..13417)
                     /gene="erm(B)"
                     /locus_tag="JXV47_002309"
     CDS             complement(12680..13417)
                     /gene="erm(B)"
                     /locus_tag="JXV47_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAX1488324.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(13542..13625)
                     /locus_tag="JXV47_002310"
     CDS             complement(13542..13625)
                     /locus_tag="JXV47_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HAX1488325.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
BASE COUNT         4853 a         2128 c         2848 g         3867 t
ORIGIN      
        1 tatgatacgt gtttgttttt ctgtgctgtt tagtgaatga ttagcagaaa tatagagagt
       61 aagattttaa ttaattatta gggggagaag gagagagtag cccgaaaact tttagttggc
      121 ttggactgaa cgaagtgagg gaaaggctac taaaacgtcg aggggcagtg agagcgaagc
      181 gaacacttga tcttttaagt tgctatcttt ttaaggtcaa tagagtatac ttatttgtcc
      241 taatatggtt ttagcagtat aattgacttg gtgaataggt catttaagtt gggcataata
      301 ggaggagtaa aatgaaaaaa tttatttatc gagttttaga aaatgacgaa gtggtggcta
      361 tttttaatga gcaacaatat gcgcaagatt ttatcgctta cgaaaagaca atttctgata
      421 agcaatttga aattgaaaaa gtagatatag ctgattggtt attgcaaccg agagaatttt
      481 agaggttggt tgaaaatggc taaaattggt tatgcacgtg tcagtagcaa agaacagaac
      541 ttagatagac aactgaaagc gttagagggc gtttctaagg tcttttcaga caaattaagc
      601 ggtcaatcgg tcgaacgccc acaattacaa gctatgctta actatattcg tgaaggggat
      661 atagttgttg ttactgaatt agatcgatta ggacgaaata ataaagaatt aacagaattg
      721 atgaatcaaa ttcaaattaa gggggcaacc ctggaagtct taaatttacc ctcaatgaat
      781 ggtattgaag atgaaaattt aagacggctg attaataatt tagtgattga attgtataag
      841 taccaagcgg aatctgaacg caaacgaatt aaagaacgcc aagcccaagg aattgaaatt
      901 gctaagaaaa aaggaaaatt caaagggcga caacctaaat tcaaagaaaa tgatccacgt
      961 ttacaacacg ctttcgattt atttttgaat ggttgttccg ataaagaagt tgaagaacaa
     1021 actggaatta atcgccgaac gtttagaagg tatcgatcaa gatacaacgt gacagtagat
     1081 caaagaaaaa aacaatgaaa agagggatag ttaatgagta cggttatttt agctgaaaaa
     1141 ccaagccagg cattagccta cgcaagtgct ttaaaacaaa gcaccaaaaa agacggttat
     1201 tttgagatca aagacccact atttacagat gaaacgttta tcacctttgg ttttgggcat
     1261 ttagtcgaat tagcagaacc aggtcattat aacgaaaagt ggcagaactg gaaacttgaa
     1321 tctttgccga tttttcctga tcgatacgat tttgaagttg caaaagataa gggaaagcag
     1381 tttaaaattg ttgctgaact tctcaaaaag gcaaatacaa ttattgtcgc aacagatagc
     1441 gacagagaag gtgaaaatat cgcctggtcg attatccata aagcaaatgc cttttctaaa
     1501 gataaaacgt ataaaagatt atggatcaat agcttagaaa aagatgtgat ccgaagcggt
     1561 tttcaaaatt tgcaaccagg aatgaattac tatccctttt atcaagaagc gcaaacacgc
     1621 caaattgccg attggttgat cggcatgaac gcaagccctt tatatacctt gaatttacaa
     1681 caaaaaggcg tacaaggtac attttcatta ggacgtgtac aaacaccgac tttatatctc
     1741 atttatcaac gccaggaagc aatagaaaac tttaaaaaag aacctttttt cctgaataat
     1801 tcatagtttt actaatagtc tttcctaaca ttgatttaat agtctttaaa gtattctgct
     1861 tcatcaccca ttaggtgatg aaaaaagaac ccctttctga tttagcggac aaatactttg
     1921 acctaatctc agaagatata aaagaaaaaa taataaaata tccgatttat actttgtata
     1981 aagaactaaa gtagttagca aatcatttac agcaaatcac tatgttccac ataccatttt
     2041 acatacttac cttatccacg acacatgttg agatagtatc gaagataaag aaagttgctc
     2101 catgttgttt ttgcgagatg gggaaatcaa agccacattg acaaccatga tgaataagct
     2161 tgctttcagt cataagctaa tcctagaacc acttttcaag tcagttagcc aaatcgatga
     2221 agaaagcgac cgtgaaagaa tggacgctat tgataagcta atggagcaac tattggaaga
     2281 acgcaatacc cttattgcac tgatgtccaa aggtttccta gaacctgctc tttttaatca
     2341 ggaacgaaat gttttagata gtgagattaa aaatcttact accgaaaaaa caaacctggt
     2401 aacgaactct gcgagtgggg ttttgcgagc aaacgagata aaggacctca ttaattatgt
     2461 gtcagcagat aattttaatg gtgactacac ggaagaacta tttgaagaat ttgtagtgaa
     2521 catcattgta aattccaggg atgagctgac attcaatttg aaatgcggtc tttccctgaa
     2581 agaaaaggtg gtgagataaa tggcatatat tccatatgga tacaaaattc aagatggagt
     2641 ggttactgtc gatgaaaagg cagcaggtca agtaaaggta ttctttgaga aatacatatc
     2701 aggactatcc cttacagtgg ctggcgaaca ggcaggtatt gaaaagacac attctgtgat
     2761 ggggcgcatt ttgaaaaacg tcaactacct tggaaatgat acgtatccag caattattga
     2821 taaagagata tttgataaag ctgaagaagt tagagataaa cgtgcaaagg atttaggacg
     2881 agtggtagag cttgccgctt tcacctctcc ccctcccaaa gaacgattca aaatgaaaaa
     2941 ggcagataat aagatgccag tggatccttt tgaacgagca gaatacttat acagtctgat
     3001 agaaagcgag gaataaagtg acagagaaaa atataatggt tattcctgct cgtaaaagag
     3061 taggaagtac agccgcaaaa gaaaagataa agaaacttcg tgttgctgcc tattgccgtg
     3121 tttctacaga aacagaagaa caaaattcta gctatgaggt tcaggtctca cactatacag
     3181 agtttataaa gaaaaataat gaatgggagt ttgctggcat ctttgcagat gatggtatct
     3241 ctggtacgaa cactaaaaag cgtgacgaat ttaatcgcat gattgcagag tgtatggacg
     3301 gtaacatcga catggttatt acaaaatcca tcagccgatt tgcgcgtaac accctagact
     3361 gccttcaata cattagacag ctcaaggata agaacatatc agtttatttt gagaaagaga
     3421 acatcaacac cacggatgcc aaaggtgagg ttttgctgac tattatggca tctttggcac
     3481 agcaggaaag ccagagcctt tcacaaaacg ttaagcttgg gctacagtac cgataccaac
     3541 aaggaaaggt gcaggtcaac cataagcgat ttatgggcta cacgaaagat gaagatggaa
     3601 atttaactat tgtccccgaa gaagctgaga ttatcaaacg catctaccga gaataccttg
     3661 agggtcagag tctagtgggc attggtcgag cccttgaaaa ggatggtatt ttaacagcag
     3721 cgggaaaacc aagatggcga ccagaatcag ttaagaagat acttcaaaac gaaaaataca
     3781 tcggagatgc ccttctgcaa aagactgtca cagtagattt tctgaccaag aaacgagtga
     3841 aaaatgaagg gcatgttccc caatattatg ttgaaaatag ccatgaagcg attattccta
     3901 aagagttatt tttgcaggcg caagaagaaa ttcatcggag aagcaatatc tacacaggag
     3961 aaggcaagaa caaaagaatt tacagtagca agtacgcttt aagtgccatc accttctgtg
     4021 gagattgtgg cgatatttat agacgggtct attggaatat ccacggaaga aaagaatttg
     4081 tctggcgatg cgtgactaga atcgagcaag gtcctgaagt ttgtaagaac cgaaccgtaa
     4141 aagaagatga actttatggt gcagtaatga ctgcgattaa taagctactt gcaggtggga
     4201 acaatatgat aaagacactg gaagagaata ttcatgctgt gattggcgaa accacagaat
     4261 accaaatttc agagattaac aactcactag aggaaaaaca aaaagaacta atcaagctgg
     4321 cgaacaaggg tcaagactat gaccacttag cagatgagat tgatgagctg agagacaagc
     4381 gacagatcct tttagtagaa gatgcctccc tcagtggcga gaacgagcga atcaatgagc
     4441 tgattgaatt tatccgcaag aacaaattcc gcaccttaga atatgatgat aagcttgtaa
     4501 ggaagataat ccagagcgtt acagtctatg aaggccactt cgtcatagcc ttcaaatctg
     4561 gcatcgaaat ggaaatatga aaaccagaag taaatagccc atgactctac agtagagttg
     4621 tgggttttct tttgcttgct gattataata atattttaat aactattgtg tttatcaacc
     4681 aaatggttta taatattctt agcgtaaact tggaggtgct gtatgactac ggcagaaatg
     4741 attaaagaac tgtgtgagca aatgaatata agtgtttccg aacttgctag acgtattggc
     4801 cagactccac agaatttcaa taaaaaatta caacgagaaa cagtaacctt ggatgagttg
     4861 aaggccattg ctgatgtgct aggtgtcaag tttgtgcagg catttatttt accagatgga
     4921 gaagaaataa aaatatctaa cgaataaagg aggatgttta tatggtaggt aatgttattc
     4981 aaatagtaac agagaaatta tcatctttgc cttttataga aggcatcgta ttagggggct
     5041 cacgtgcaag aggcacccat acagaaaatt ctgatataga tatcggaatc tattacaatt
     5101 cagactcatt tgacctgaca gcgattaatc aaattgctac agagttggat gatgagaata
     5161 gaaacaacct tgttgtacct cccggagcgt ggggtgattg ggttaatggc ggtggatggt
     5221 tagttataaa cgggtgtcat gttgacttga tattacgtga tataaaacgg gtggaacaaa
     5281 taatcaaaga tacggagcaa ggaattgtta ctgccaatta tcagaccggg catccccatg
     5341 gttatataag tgctatgtat cgtggagaat tagcgattag taaaatacta tatgctaaga
     5401 acgaaagctt atgcgaatta aaaaagcagg cagaaattta ccctactgct ctaaagaaaa
     5461 gcttgatgaa cttttttata tttgaagctg aattctcttt aatgtttgta aaagcaaatg
     5521 cgggggcaga ggataaatat tatattgcag gccatgtttt tcgtattatt tcatgcttaa
     5581 atcaagtact atttgcatgt aataatgctt attgcattaa cgaaaagaaa gctataaaac
     5641 tgcttgaaac ttttgaatat aaacctgaaa aatatgccga aagagttaat catatttttg
     5701 aagtactcgg tctttctctt tttgaatgct acgacatgac cgagaaactt tataaagaag
     5761 tgaatgaaat tgtatcggag ataaataact ttttaaacga ggagagttca gatgaaagaa
     5821 aacaaatatg atgataatat attttttcaa aaatacagtc aaatgagtcg ctcgcagaaa
     5881 ggactggctg gtgcgggaga atgggagact ttgaaaaaga tgctacctga ttttaagggt
     5941 aagcgtgtgc ttgatttagg atgcggctat ggatggcact gtatatatgc gatggaaaac
     6001 ggtgcttcct ctgtagtagg tgttgatatt tctcataaaa tgctcgaagt agcaaaagga
     6061 aaaacccatt ttccacagat tgaatatgaa tgctgtgcca tagaagatgt ggatttccca
     6121 gaggagagct ttgatgtaat actaagttcg cttgcgtttc attatgtagc agactatgag
     6181 aatttaataa aaaagatata taggatgctg aaggctggtg gcaatttagt ttttacagtt
     6241 gaacatcctg tttttactgc tcatggaaca caagactggt attataacga aaaaggagaa
     6301 atactgcatt tcccggtgga caattattat tatgagggca aacggacagc tatgtttttg
     6361 gaagaaaagg ttacaaaata tcatagaaca ctgaccacat atctaaatac actgctttca
     6421 aatagtttta taataaatca gattgtggag ccacagccgc cagagaacat gatggatatt
     6481 ccggggatgg cggatgaaat gcgacgccca atgatgctga ttgtatcggc aaaaaagaag
     6541 atgtaataat atagaaaaaa taaacgagga gtatgtaaat gagatcagaa aaagaaatga
     6601 tggatttagt actttcttta gcagaacagg atgaacgtat tcgaattgtg acccttgagg
     6661 ggtcacgcgc aaatattaat atacctaaag atgaatttca ggattatgat attacatatt
     6721 ttgtaagtga tatagaaccg tttatatcta atgatgactg gcttaatcaa tttgggaata
     6781 taataatgat gcaaaagccg gaggatatgg aattattccc acctgaagaa aagggatttt
     6841 cctatcttat gctatttgat gattacaata aaattgatct taccttattg cccttggaag
     6901 agttagataa ttacctaaag ggcgataaat taataaaggt tctaattgat aaagattgta
     6961 gaattaaaag ggacatagtt ccgactgata tagattatca tgtaagaaag ccaagcgcaa
     7021 gggagtatga tgattgctgc aatgaatttt ggaatgtaac accttatgtt attaaaggat
     7081 tgtgccgtaa ggaaatttta tttgctattg atcattttaa tcagattgtt cgccatgagc
     7141 tgctgagaat gatatcatgg aaggtcggca tcgaaacagg ctttaaatta agtgtaggca
     7201 agaactataa gtttattgaa aggtatatat ccgaggattt gtgggagaaa cttttgtcca
     7261 cctaccggat ggattcctat gaaaacatat gggaagcatt atttctatgc catcaattgt
     7321 tcagggcggt atccggtgag gtggcggaaa ggcttcatta tgcctatccg gagtatgata
     7381 ggaatataac aaaatatacc agggacatgt ataaaaaata cactggtaaa accggctgcc
     7441 tggatagcac atatgccgct gatatagaag agaggcggga acagtgatta cagaaatgaa
     7501 agcagggcac ctgaaagata tcgataaacc cagcgaacca tttgaggtga taggtaagat
     7561 tataccgagg tatgaaaacg agaattggac ctttacagaa ttactctatg aagcgccata
     7621 tttaaaaagc taccaagacg aagaggatga agaggatgag gaggcagatt gccttgaata
     7681 tattgacaat actgataaga taatatatct ttactaccaa gacgataaat gcgtcggaaa
     7741 agttaaactg cgaaaaaatt ggaaccggta cgcttatata gaagatatcg ccgtatgtaa
     7801 ggatttcagg gggcaaggca taggcagcgc gcttatcaat atatctatag aatgggcaaa
     7861 gcataaaaac ttgcatggac taatgcttga aacccaggac aataacctta tagcttgtaa
     7921 attctatcat aattgtggtt tcaaaatcgg ctccgtcgat actatgttat acgccaactt
     7981 tgaaaacaac tttgaaaaag ctgttttctg gtatttaagg ttttagaatg caaggaacag
     8041 tgaattggag ttcgtcttgt tataattagc ttcttggggt atctttaaat actgtagaaa
     8101 agaggaagga aataataaat ggctaaaatg agaatatcac cggaattgaa aaaactgatc
     8161 gaaaaatacc gctgcgtaaa agatacggaa ggaatgtctc ctgctaaggt atataagctg
     8221 gtgggagaaa atgaaaacct atatttaaaa atgacggaca gccggtataa agggaccacc
     8281 tatgatgtgg aacgggaaaa ggacatgatg ctatggctgg aaggaaagct gcctgttcca
     8341 aaggtcctgc actttgaacg gcatgatggc tggagcaatc tgctcatgag tgaggccgat
     8401 ggcgtccttt gctcggaaga gtatgaagat gaacaaagcc ctgaaaagat tatcgagctg
     8461 tatgcggagt gcatcaggct ctttcactcc atcgacatat cggattgtcc ctatacgaat
     8521 agcttagaca gccgcttagc cgaattggat tacttactga ataacgatct ggccgatgtg
     8581 gattgcgaaa actgggaaga agacactcca tttaaagatc cgcgcgagct gtatgatttt
     8641 ttaaagacgg aaaagcccga agaggaactt gtcttttccc acggcgacct gggagacagc
     8701 aacatctttg tgaaagatgg caaagtaagt ggctttattg atcttgggag aagcggcagg
     8761 gcggacaagt ggtatgacat tgccttctgc gtccggtcga tcagggagga tatcggggaa
     8821 gaacagtatg tcgagctatt ttttgactta ctggggatca agcctgattg ggagaaaata
     8881 aaatattata ttttactgga tgaattgttt tagtacctag atttagatgt ctaaaaagct
     8941 ttaactacaa gctttttaga catctaatct tttctgaagt acatccgcaa ctgtccatac
     9001 tctgatgttt tatatctttt ctaaaagttc gctagataga gttctatatt agagatgtaa
     9061 agagttttgg tgaagaggtt tgtgagtatg gcttttataa ccagggtgca atgagaagca
     9121 ctaacagcag ctagcttaag aacgcatagg atatactttt tatggaagtc acagaggagg
     9181 aataaaattt gaacaggatt aacagagtaa cctctattct tattcagctg caatcaaaaa
     9241 aaataattcc tgccaaagaa attgcacagc gatttaatat aagcttaagg acagtttaca
     9301 gagatatccg gacacttgaa gaagccggaa taccaattgg atctgaggcc ggaaaaggat
     9361 attttcttgt agagggcttc ctacttccgc cggtaatgtt tacagcggcg gaagtgggtg
     9421 cattgattac agcagggaaa tttttaaatt gccatggaga tgaatcattt ataaaggatt
     9481 ttgattcagc tatgtataaa atcaaatcta ttttgaagca tggtgaaaaa aactatgcac
     9541 aggagttgga gaacagtatt aacgtgtaca gcacatctgg acagaaaaat acattggcgg
     9601 ataacgttat tgcagcaatt cagactgcaa tctgcaataa aagggtaata tcaattcaat
     9661 atcctgcatc aggagggcaa gaaccggaaa gcagaatgat agagcctata tcactggggt
     9721 tttatgaaca gaactggtac ttaatcggtt ttgcaggcta agaaatgaat ataggaattt
     9781 tcgtgtggat cggattaaaa gcatttgcat agaagaagag ctctgtcaaa gccatgatgg
     9841 ctctttggaa caaatattaa aacaaatgct ttcatataaa aaactatatg ccctacaatg
     9901 ccgttgtaaa aattggggaa aagggatata ttgattttat atctttctca aaataaatat
     9961 aaaagccctt taaagagggc ttttatatat taatcacaaa tcacttatca caaatcacaa
    10021 gtgattaatc acaaatcact tgtgatttgt gattcttaat gatacaatat tactatacaa
    10081 aaaaagaatg gggcgtagtt atggagaagg aaaaactaaa aatacttgaa gaattaagac
    10141 gtattttaaa caataaaaat gaagcaatta ttatcttgaa taattacttt aaaggtggtg
    10201 ttggaaagtc caaattatcg actatgtttg cttacttgac agacaaattg aatttaaaag
    10261 ttttaatgat cgataaggac ttacaggcaa cattgacaaa agacttagca aaaacttttg
    10321 aggtagaatt gccacgtgtc aatttttatg aaggcttgaa aaatggaaac ttggcttctt
    10381 ctattattca tttgactgat aatttagact tgatccctgg cacgtttgat ttgatgttac
    10441 tgccaaaatt aactcgctca tggacgtttg aaaatgaaag tagattgctt gctactcttt
    10501 tagcaccttt aaaaagtgac tatgatctta ttattattga tactgtacca acgccaagcg
    10561 tttatacaaa taatgcaatc gtggcgagtg attacgttat gatcccttta caagcagaag
    10621 aagaaagtac aaacaacatt caaaactata tttcctattt gattgatttg caagaacagt
    10681 ttaaccctgg actagatatg attggttttg ttccttattt agttgatacg gacagcgcaa
    10741 cgataaaatc aaacctggaa gaactgtaca aagaacataa agaggataat ttggttttcc
    10801 gaaatattat caagcgaagt aataaagtaa gtacttggtc taaaaatggc attacagaac
    10861 acaaaggcta tgacaaaaaa gttttgtcta tgtatgagaa cgtatttttt gaaatgattg
    10921 agcgaatcat tcaattagaa aatgaaaaag aatagaatca caaatcacaa gtgattaatc
    10981 acaaatcact tgtgatttgt gataggtgat gataaaataa atagtaagaa gaaatagaaa
    11041 gaagtgagcg atcgtgggaa atttaggcgc acagaaagca aaacgaaatg atacgccaat
    11101 cagcgcaaaa aaagatataa tgggggataa gacggttcgt gttcgtgccg acttgcacca
    11161 tatcataaaa atcgaaacag caaagaatgg cggaaacgta aaagaagtta tggatcaagc
    11221 cttagaagaa tatatacgga aatatttacc tgacaaactt taaaaggagt gaaaatgaaa
    11281 tggcagttac gtatgaaaaa acatttgaaa ttgaaatcat taatgagtta tcggcaagtg
    11341 tttataatcg ggtattaaat tatgttttga atcatgaact agatactaaa aatactcgtt
    11401 tactagaagt gaatctttta aatcaattag aagtggcaca agaagttgat ttatttcaac
    11461 aaccatttga agaattacaa gctattcatg agtattggcg gtcaatgaat caatattcaa
    11521 aacaaatttt gaataaagag aaagtggctt aacatggcga atattactga cttcaccgaa
    11581 aagcaatttg aagatcgttt agaaaagaat gttgaacgac taactaaaaa tagactagcg
    11641 gttgaatcgc caaccgcttt tttacttggt gggcaaccag ggtcagggaa aaccagtttg
    11701 cgatcagcaa tttttgaaga aacacaaggg aatgttattg tcattgataa tgataccttt
    11761 aaacaacagc acccaaattt tgacgaatta gtgaaactct atgaaaaaga cgtagtaaaa
    11821 cacgttaccc cttattcgaa tcgcatgaca gaagcactta ttagccgttt aagcgatcaa
    11881 ggctataatt tagtgattga aggaacagga cgaacaacag acgttcccat tcaaacagcc
    11941 acaatgcttc aatctaaagg ttatgaaaca aaaatatacg tcatggcagt accgaaaatt
    12001 gaatcatact taggaacgat tgaacgatat gaaaccatgt atgcagatga tccaatgaca
    12061 gctagggcaa caccaaaaca agcgcatgat attgttgtca aaaacttacc gaccaattta
    12121 gaaacccttc ataaaacggg cttatttagc gatataaggc tttacaatag agaaggagtg
    12181 aaactctatt caagcttaga aacgccttcc attagtccga aagagacctt agaaagagaa
    12241 ttaaatcgta aagtatcagg gaaagaaatt caaccgactt tggagagaat agagcaaaaa
    12301 atggttcaaa atcaacacca agaaacccct gaatttaaag caattcaaca aaaaatggaa
    12361 agcttgcagc tacctacacc accaataccc aaaacaccta aacttccagg tatttaaacc
    12421 ttaaaaaagg aaaagagtag ttaccaaaaa acggtaacta ctcttttttt ataaaaacat
    12481 ttcctcatgt tggggtcccg agcgcctacg aggaatttgt atcgataaga aatagattta
    12541 aaaatttcgc tgtttttttc taatttcatt ttgaggtgaa ttaattggta gttattagag
    12601 gtgccctata cctaataatt tatctacatt ccctttagta acgtgtaact ttccaaattt
    12661 acaaaagcga ctcatagaat tatttcctcc cgttaaataa tagataacta ttaaaaatag
    12721 acaatacttg ctcataagta acggtactta aattgtttac tttggcgtgt ttcattgctt
    12781 gatgaaactg atttttagta aacagttgac gatattctcg attgacccat tttgaaacaa
    12841 agtacgtata tagcttccaa tatttatctg gaacatctgt ggtatggcgg gtaagtttta
    12901 ttaagacact gtttactttt ggtttaggat gaaagcattc cgctggcagc ttaagcaatt
    12961 gctgaatcga gacttgagtg tgcaagagca accctagtgt tcggtgaata tccaaggtac
    13021 gcttgtagaa tccttcttca acaatcagat agatgtcaga cgcatggctt tcaaaaacca
    13081 cttttttaat aatttgtgtg cttaaatggt aaggaatatt cccaacaatt ttatacctct
    13141 gtttgttagg gaattgaaac tgtagaatat cttggtgaat taaagtgaca cgagtgttca
    13201 gttttaattt ttctgacgat aagttgaata gatgactgtc taattcaata gacgttacct
    13261 gtttacttat tttagccagt ttcgtcgtta aatgcccttt acctgttcca atttcgtaaa
    13321 cggtatcggt ttcttttaaa ttcaattgtt ttattatttg gttgagtact ttttcactcg
    13381 ttaaaaagtt ttgagaatat tttatatttt tgttcatgta atcactcctg aagtgattac
    13441 atctataaat aaatacagaa gttaaacgat ttgtttgtaa ttttagttat ctgtttaaaa
    13501 agtcataaga ttagtcactg gtaggaatta atctaacgta tttatttatc tgcgtaatca
    13561 ctgtttttag tctgtttcaa aacggtagat gttttatcta cattacgcat ttggaatacc
    13621 aacatgacga atccctcctt cttaattaca aatttttagc atctaattta acttcaattc
    13681 ctattataca aaattt
//
LOCUS       DADGKS010000073        13083 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.074, whole genome shotgun sequence.
ACCESSION   DADGKS010000073 DADGKS010000000
VERSION     DADGKS010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13083
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.074"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(78..2198)
                     /locus_tag="JXV47_002311"
     CDS             complement(78..2198)
                     /locus_tag="JXV47_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAX1488326.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLAKGKNVIYIHLESFQQFLIDYKLTDENG
                     LQLEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHKG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2428..3606
                     /locus_tag="JXV47_002312"
     CDS             2428..3606
                     /locus_tag="JXV47_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HAX1488327.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIVGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3622..4380
                     /gene="aroD"
                     /locus_tag="JXV47_002313"
     CDS             3622..4380
                     /gene="aroD"
                     /locus_tag="JXV47_002313"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HAX1488328.1"
                     /translation="MVWVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLAGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4403..4888
                     /gene="ybaK"
                     /locus_tag="JXV47_002314"
     CDS             4403..4888
                     /gene="ybaK"
                     /locus_tag="JXV47_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HAX1488329.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSHIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4959..6212)
                     /locus_tag="JXV47_002315"
     CDS             complement(4959..6212)
                     /locus_tag="JXV47_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAX1488330.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6328..7677
                     /gene="gdhA"
                     /locus_tag="JXV47_002316"
     CDS             6328..7677
                     /gene="gdhA"
                     /locus_tag="JXV47_002316"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HAX1488331.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNAQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7789..9135
                     /locus_tag="JXV47_002317"
     CDS             7789..9135
                     /locus_tag="JXV47_002317"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HAX1488332.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9443..9829)
                     /locus_tag="JXV47_002318"
     CDS             complement(9443..9829)
                     /locus_tag="JXV47_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAX1488333.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYTEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            10708..10920
                     /locus_tag="JXV47_002319"
     CDS             10708..10920
                     /locus_tag="JXV47_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488334.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPTELVS"
     gene            complement(11198..12997)
                     /locus_tag="JXV47_002320"
     CDS             complement(11198..12997)
                     /locus_tag="JXV47_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAX1488335.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRSFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
BASE COUNT         4290 a         2353 c         2577 g         3863 t
ORIGIN      
        1 tattctaaga tttctcttta ccaacatcat ttgacaaaga gcctaatttt gtcgctgctc
       61 cttttaaatt tattttatca ttcggaagaa cttgtggtcg ttccgtgaag ttcttggtac
      121 gtttgcgttt tataaagatc aacagttgat tgtcccttgt gttcactaaa gacactagtt
      181 gacttgtcac caagagattt ttcagcttct tttaatttct ctaagccatt cttgtagtca
      241 taatcactgg tatcaattgg gtctaatcca ctattcgtat agaaccgaag aagatcacca
      301 ttattgattt ggtcagaaac agctaactgt ttatcaactt tttctttcag tgaatcaatt
      361 tcattctgta cttcctcagt aggttcagta atagcttcac cagtttcgtt actatagatc
      421 gtaccaccgt agtaagtata ttttggtgta acaaaatcac catcacggaa agaaacaagc
      481 tgttcatgat ctttcgagaa tagatcttgt cctaactgaa tataattttt tgtatctaca
      541 cctagtaagt gaagtaatgt aggcaaggca tcaacttgtc cgccgtaagt gtgattgatt
      601 ccgccctgtg tttgtccagg gatatggatc atataaggga cacgctgcat ttgtgcattg
      661 tcgtagtttg tccaagtaga acttgttttt ccaactaatt cagctagatt tttatttctt
      721 gaattcgaga caccgtaatg gtcaccgtaa aggacgatga ctgaattatc atacaagccg
      781 ctttctttca aataattgaa gaattcttgt acggcggtat ctaaataatt ggctgtcgca
      841 aagtaaccgt tgatcgtttc atcatttgta ttggctaacg ggaatcctgc ttcgtcattg
      901 gtgaattttg aataaggata atggttagat acagcaatga attttgaata aaatggttgt
      961 tgcagacgtt ccaagtattg tacggattgt tggaaaaatg gtttatcatg caacccgtat
     1021 tggaacgaat tgtcatcatt aacatcataa taagaagaat caaagaaata atcatatcct
     1081 aaattcttgt atgtctcgtt tcgattccag aatgtaccag cgttcccatg gaataccgca
     1141 ctagtgtaac cttgtgtttg acttaaaata tcaggtgcag cttggaaagt attttttccg
     1201 cctaattgtg tgaacaagga gccttgattc aagccaaaca atgaattttc catcagcgtt
     1261 tccgcatcgc ttgtttttcc tgcttttact tgatggaaaa agttgtcaaa actgaacgtg
     1321 ctgttgctgt ggtaaagact attgatgaaa ggtgtaactt caagctggag accattctca
     1381 tctgtcaatt tataatcgat caggaattgc tggaagcttt ctaaatggat ataaatcaca
     1441 ttttttcctt tagcgagccc gaacaaatca tcatttggtg ctgcataatg ttcttttaca
     1501 taattttcta cttctttcat atcattggga cttgcttctg cccgcacttg gtttgtctgg
     1561 taagtttgaa caccgtcata aaccatgaaa gcattcaagc caagatattt gaccaaataa
     1621 tcacgagaga atgttcgagt cagcaattct ggacgatcag cttccgccat aaaaagattt
     1681 cctgagaaaa tcataactgc taatgtagag atcgcaaaag ccattcttgc tcggatcggg
     1741 cgagggtcca acttgatttt ttttgcaatc agcagaacag tcaagataat aaaatcgatc
     1801 caatagatca catcatatgg gcgaaacagt cgaatggcac tttctcccag accactcgct
     1861 actttcccag cacctaaaat cgtgttgatc gtaatgaagt ccgtgaattc tcgataataa
     1921 gtgacattcg aaaaaacaag caatgtcaaa agaaaataaa tgaccatcat cgtgatataa
     1981 gcaactctag ggcgtctgat ataaagagca attccaagta ataacaatgt agttgcaata
     2041 gggttgataa acaagataaa gtattgaatg ccactttcga ttccgagatg gaaatcaact
     2101 aaataggcaa aaatcgtttt caaccaaagt aaaacaacta gtaaagaaaa aaatccgagc
     2161 ctcttattca aaaaggcagg tgtttttata catttcaaga taatcttcct ttctgcactt
     2221 cttaatcaca gaagtgtcat gaaaccatgt tacacagctc acttattctc atttatttta
     2281 ctagtatgac aatatagtgt caattgaaac cagaagttta tgctgtttca ttaaggtttt
     2341 ctttaagctt catgaaaaaa tgagcagtaa gacaagtcct atgttttttg ttatacttgg
     2401 gaagagaaag ctaaagcagg tgaaggaatg aaagtaaaag taaaaaaaag agcaagcaat
     2461 cgattgaaaa aaggatatcc actgatccaa aaagaagacc ttgctcatcc ccaaaaagaa
     2521 accacgcaat gggtggaatt agttgattcg caaaaccaat ttatcgcaaa aggatatcta
     2581 ggaaagcaga ataagggaat cggttgggta ttgagccagc agaacatccc atttgatcaa
     2641 tctttttttg aagaattttt tgtgaagtca aaagaaaaaa gaactttctt tttttcagat
     2701 gattctacta ccgcttttcg tatattcaat ggagaaggag acgggatcgg cggtctgatt
     2761 gttgattatt atgcaggtta tgctgttttt tcttggtata acgaaacgtt atatgcacat
     2821 cgtgaattat tgattcaagc ttttcgtgaa atctacccgg aaatcgtagg aggctatgag
     2881 aaaattcgat ttgaatcagt aaatctgcct gagagccagt tcatttacgg aaaagaggca
     2941 ccggaaccct tgatcgtaaa agaaaacgga gtaaaatttg ccgtttattt aaatgaagga
     3001 ttaatgactg ggatcttttt agaccaaaaa gaagtacggg gatcattagc agaaggtttc
     3061 gcttctggga aaacagtttt gaacatgttt agttataccg gcgccttttc tgttgctgcc
     3121 gcaatgggag gggcaatcga aacaacaagt gtcgatctag caaaacgcag tttaaaaaaa
     3181 acacaggaac agtttgaagt gaatggtttg gatgtcgatc agcaaaaaat cattgttatg
     3241 gacgtattcg agtatttcaa atacgccaaa agaaaacaat ttttatatga catgattgta
     3301 ttggatccac caagttttgc cagaaataag aaaaaagtct ttcgcgtagc aaaagattat
     3361 ggggaactgg tcaaggatag tctggatatt ttagcagaag acgggatact tattgcgtct
     3421 acaaatgctg cgaatgtctc gatagaacaa ttccaaacaa tgattgaaga ggaattccat
     3481 gccaaaaatg tttcttttga acaacttgct ttatatcgtc tgccaaaaga tttccagacg
     3541 acggatacct ttttagaagg caattatctg aaagtgtttg tttatcaaat taaaaataac
     3601 cattagaagg agcgatgcag aatggtttgg gtaaagggat tgaatatagg aagcggtaga
     3661 ccaaagattt gtgcgcctct tatcggggcc gtccgagagg aagtattacg tgaagcagtt
     3721 cttgcacgtg aagcaggggc cgatttagtc gaatggcgag tcgatcatta tcgtgaagtt
     3781 ttttcttttg atgaagtagc agaaacattg gttcttatcc atgagatgct tgatggactg
     3841 ccgttattat ttacgtttcg taccttagct gaaggcggag aacaagacat atcgatccgt
     3901 cagtatcgcg acctttatga acatgtgata cacacaggat tagtagatat ggtcgatatc
     3961 gagttgttca aagtagaaag tctaggaaaa agactgatag aggaaatcaa gtctttaaac
     4021 attcctttaa ttatcagtag tcatgatttt aaagaaacac cagcagaccc tgtcttgctt
     4081 taccgattga atgttatgga acattttgga gccgatatcg gaaaactggc agtaactccc
     4141 aataatgaac gagatgtttt gcggttgatg gagttgacta gacgggcaaa tgcttttgtc
     4201 tccatgccta ttattacgat gtccatggga aatcttggta aaatttctcg tctggctggc
     4261 ggaacgacgg gttccgttat gacatttggt tccttaagca gcgattctac ttctgctcca
     4321 ggacaattac cggtcaaagc attgaagcaa attattcaat tattaaatga accgttgtag
     4381 aacaagtttg aggtgatatt ttttggcaaa gaaaaaaata gtaaaaacga atgcaatccg
     4441 tatggtcgaa caaaaaaaga ttccctatac agagcacgaa tatgagtggg acgaaagcca
     4501 cctaagtgcg tcatcggtcg ctgaacagct tccagaaagc caatctcata tatttaaaac
     4561 actggttgct gtgggcaatg tgacggggcc tcttgttgct gtgataccgg gagaagccga
     4621 attgaatcta aaaaaattag caaaagtttc agggaataaa aaagtagaaa tgctccattt
     4681 aaaagatttg gaagcaacga ccggatacat acgtggtggc tgctcgccta taggtatgaa
     4741 aaaactattt cctacttatt tagatcaaat tgcagaaagc tatgaacaaa tcattgtctc
     4801 ggctggcaga agagggctac agatggagtt agcacctcaa gatatctgtg cattaacgag
     4861 cggacaattt gcagatataa aacaataaat catacgtata aaagaaagaa ggaggccggg
     4921 atgttgtttg tccagtctcc ttctttcttt tttatacatt atgctctttg cccggcattc
     4981 attcctgcta catgccctgt agcgaaagcc gctgtgatat taaagccgcc agtataacca
     5041 ttgacatcca gtaattctcc cgcaaaatac agaccatcaa tgattttact ctccaatgtt
     5101 ttaggataaa tttcctttag agaaacccct ccgccagtta caaatgattt ctcaatagga
     5161 aaagttttgt tgattgatag cttaaactct ttgcatagtt gaacaaaatc ttgaatttgt
     5221 ttttgagagg cttgttgtcc tgtcagatga tccatttcaa gccgctcaag aaagaaaact
     5281 aacaatcgct caggcaatat accatgccaa gcattgacca agttcttttt ggttgcttta
     5341 cttttttctg tcaatatatg aataagctct tgtttggttt gtgtagggaa acaatccaga
     5401 gaaagtgtca ctggttctcc cgttttctct aattctttat tgacaaaact tgaacaacgc
     5461 agtgcagccg gaccagaaat accgaaatgg gtgaaaagta aatccatcgt atgttcagtc
     5521 aatacacgac cttttttatt taaaacgcgt aaagtgatgt cttgtaaaga aagcccttga
     5581 agtgttttct cctgaatata cggttcatcc gatatcaagg gggactctgt cgcataaaga
     5641 ggcgtcaccg tgtgacccac tcgcttcacg atcttgtacc catctccagt agaaccagta
     5701 gatggataag tccgtccacc agttgttaag ataatggcag gagcatggaa ctcttcgaat
     5761 tccgtgcgta taccgtaaat tttatgttct ttgtggatca atttctctac tcgagtagag
     5821 aatagaagcg tcacatctag ttctttcaga cgattgagca atgcttcgat aatcgttttt
     5881 gatttatttg ttacaggaaa catccgtcca tgatcctctt cttttaaatg tacgccttgt
     5941 gattcaaaga agttcatgat atcgaaatta ttccattgcg caaacgtact atataaaaac
     6001 tttccatttc caggaatatg tgcaatcaaa tcatcaacag gacgattgtt cgtaacattg
     6061 caccgaccac cacctgtcat cagtagtttt tttcctgctt ttttgttttt ttcgatcaag
     6121 agtacgcgtg cgccttgttc agctgcactg atcgctgcca tcatcccgct tgttccagcg
     6181 ccgactacga tcacatcata cagtttttcc attccctcac ctcaaggaaa gtgtagcata
     6241 tctgaagaaa gaaaacagaa aaaatgtttt gagccaaaag agaaaatgag ctaaaatgag
     6301 ggaagataag caaaggagcg tggaacgatg acaaacgcaa cagaatatgt tcaagcaatt
     6361 caagaaaagc tacatcaaaa ggatcaaggg caagaagaat ttttacaagc aatcgatgaa
     6421 ttcatgccca cggttatgtc ttttttggac actcatcccg aatatatcga aaagaatatc
     6481 ttagaacttt taacggaacc agaaagagtt attcaatttc gagtgccttg gcaagatgat
     6541 gaaggaaact ggcgagtaaa tagagggtac cgtatccaat acaactcagc tatcggccct
     6601 tataaaggtg gattgcgctt ccatcctagt gtcaatctaa gtatcttgaa atttttggct
     6661 tttgaacaga ttttcaagaa tagtttaacc ggtctgccaa tcggtggagg aaaaggcgga
     6721 agtgacttcg atcctaaagg aaaatctgat aatgagatca tgcgtttttg tcaaagtttc
     6781 atgctggaat tgtcaaaaca tatcggccca tcgattgatg ttcctgcggg agatatcggt
     6841 gtaggagcta gagaaatcgg ctatttgttc ggcgaatata aacgattgaa aaaatatgat
     6901 actggtgtgt tgacaggtaa acctttggat ttttggggaa gtaagatacg tacggaagct
     6961 actggttatg gattagtgta ttatgtcaaa catctattga acgaagaaaa agattcattt
     7021 aatcaaaaaa cagtttttgt ttccggaagc gggaatgtag ccatttatgc aatcgaaaaa
     7081 gtgcaagagc taggcgggaa agttgttaca tgttcagatt ctagcgggta catctatgat
     7141 ccagaaggaa tagatgtgaa actattgaaa gaagtcaaag aaatcaatag acaacgtttg
     7201 acggaatacg caaaccaacg tccttctgct atttatcatg ctggagaatc tgtttggaca
     7261 ttgaaagaaa aagcggatat cgctttgcca tgtgctactc aaaatgaaat agacgaaagc
     7321 ttggccgaaa tcttagtaga aaatgggatc aaaatcgtag cagaaggcgc taatatgcca
     7381 tgtacagtaa aagctgtttc tgttcttcat gaagcaggcg tgtggtattg tccaggaaaa
     7441 gctgctaatg ctggaggagt agcagtatct gctttagaaa tgagtcagaa cgcccagcga
     7501 ttgacttggg aaagagagca agtggatgag cagctggatc aaatcatgga aacgatttac
     7561 catacgtgtc gccaaacagc agccgagtac ggcgacgaaa aaaatctgct tcttggagca
     7621 aatgttgctg gatttgaaaa agttgccaaa gcaatggcag cagaaggttt agtttgaaaa
     7681 atgaaacttt cttggaaata ttgtcagcat tttgtttatt tgcttgaaaa ataataaaaa
     7741 aaaacgtaaa gtattacctg tagagtaaac ctataaggag gagaacaaat ggcacacatt
     7801 cattttgact attcaaaagt agcaccgttt gtcaacgaac aagagttagg gtacatgcaa
     7861 agccaagtaa cagcagccca caacgaatta cgggaaggta ctggcgcagg aagcgacttc
     7921 cgcggctgga tcgatttacc aacgaactat gacaaagaag aatttgcacg tatcaaagaa
     7981 gcagctaaaa aaatccaatc tgattctgaa gtattagttg ttatcggtat cggtggttct
     8041 tatttaggcg ctcgtgcagc gatcgacttc ttgaatcaca cattcttcaa tttattagat
     8101 agcaacacaa gaaaagcacc acaaatcttc tttgccggaa attcaatcag ctcaacatat
     8161 attgctgact tgatcgaagt aatcggtgat cgcgactttt cagtaaacgt tatttcaaaa
     8221 tctggaacaa ctactgaacc agcgattgcg ttccgtgtat tcaaagagct tcttgttaag
     8281 aaatatggac aagaagaagc aaacaaacgt atctacgcta caacagataa agcaaaaggt
     8341 gcagttaaag tagaagcaga tgcagaaggt tgggaaactt tcgtgattcc tgatgacatc
     8401 ggcggacgtt tctctgtatt aactgctgtt ggtttgttac caatcgctgt tagtggtgca
     8461 gatatcgatg cattgatgca aggtgccgct gatgcaagca aagcatactc aagcgacaaa
     8521 ctagaagaaa acgaagctta ccaatacgca gcaatgcgca acattcttta ccgtaaaggc
     8581 aaagtaactg agttgttgat caactatgaa ccaggaatgc aatacttctc agaatggtgg
     8641 aaacaattgt atggtgaatc tgaaggaaaa gaccaaaaag gcatctatcc ttcaagcgca
     8701 aacttctcaa ctgatttgca ctctttagga caattcatcc aagaaggacg tcgcaatatt
     8761 tttgaaacag ttgtgaaggt tgaaaaacct cgtaaatcaa tcacaattcc tgaacaagca
     8821 gaagatttag acggtctagg ctacttgcaa ggaaaagaag tggacttcgt aaatacaaaa
     8881 gcatttgaag gaacattgct tgctcataca gacggtgacg tgcctaactt gctagtcaaa
     8941 attccagaaa tggatgctta tacattgggt tatacaatgt acttctttga aattgctgta
     9001 ggtatttcag gttacttgaa tggaatcaac ccattcgacc aaccaggtgt agaagcttac
     9061 aagaaaaaca tgttcgcact tctaggcaaa ccgggctttg aagatcttgc taaagaattg
     9121 aacgaacgcc tgtaagataa gggtttttcg ctagatttaa ataatcagtg atagaaacat
     9181 gttcgcttta aaatgaaaac tggtacccat ttaggtactc aaacatactg catcgtttat
     9241 tcagaataag gggctgtgac aagacgtttg tcacagtccc ttgtttgtat agaaatcgat
     9301 tgattgcctt gctctttagt ttgttttagg actttaagaa cagtgaggct gacttcgaag
     9361 gttaattctg tttttttgtt ttctagaatc agtaagcaaa aaagcactca cttcgagtgc
     9421 ttttttgcga tatattctta gcttaagata ggcctaattt ttcttttaca gatgagggta
     9481 ccttatcgct ggtaattact tttttctcta tgatccgctt ttcgcttgct ttcaactgca
     9541 agatcgttcc ttcggtgtaa gcagaaccat tggcagagtc accagaagta atgacatcga
     9601 aatctaactg tcttttttca ccgttttcag cataagcatc tacgttgtat ttaaaacctc
     9661 ttccaattac ttccccatta tctgctttga tatcagtttc tgcaggcatt ggagctttga
     9721 ctaccgcata ataatcttta cctacataag tagactgata gtagtcccaa cctttccatc
     9781 ctataaaagc aatcaatatg ataacgatca accctaaaat ttttttcatg aaagatctcc
     9841 ttttttattt ttattatatt aaatattata cagataataa cggaatatta tcatcgaaac
     9901 agctaacaaa attgtcataa aaaacgagat ggttgatatt agaacttgtg tttttgttta
     9961 ggtctagaga taaagagaga caatttccaa atatatgtaa tgaatacaaa aagacgtttg
    10021 tcgcggatta ccgttacaaa cgtcttttat tgattttccg agatctcatc agtcgccatt
    10081 tggaatggtt cactccttat ctagattcgt ttaatgctcg gactgcttgt tcgattgtaa
    10141 taccaaacgc aacgttattt tcgttttgtg catcaatcgc cataaaacgg ttagaagttg
    10201 tatcaaaagc tacgcggtat tgcatatttg tttttgtaaa cgtcataaaa ttcatctcct
    10261 ttgtaatgta atttagttct tgaaagtttc ctttaaactt tcgaacttat accaagttta
    10321 gcatcgtacg ttttttgatg caattaaaaa gcatttatca ttttccttat ttattttttc
    10381 ttaaatggtt tagctatttt cttttaatcc gataagtagc ccaatcatca aggttacaaa
    10441 tactattgct tgaatataaa tcatatgctc acctctttat aaataactta gcaatataaa
    10501 gaaaaaaacg cacgaacaac ataggaatat aaacaaacgt ttttgtcaca acgtctaaga
    10561 tcgtgttaaa aaatagttat ctaaaaagca gaaagatact caaaataaaa aataaaaaaa
    10621 tgaataaaaa cgttttcaaa tacaaggtaa tttgttatta taaaataaag aaaaaacaaa
    10681 ataaaaataa agaaaagagg gaatgaaatg gtaaaagcag aagtaggaag atcttatata
    10741 tgcaaaccga tcggagtatc tcatgaacta atcggctgta ttgaacgtac atatatcaac
    10801 acggctgtcg tgtatgttga aagttatgac caacgagact atcaacttat caatgaaagc
    10861 aagtatcgca tgctcgtaaa attctgtgat attagcgcac ctactgaatt ggtttcttaa
    10921 acagtatttt tgagaattcg caagaactcc cttataatat aaataaagac agaagggagc
    10981 gagaagatat gccaaaaaga aaaagttcag ggaaaatggg aattattctt gcagtgatct
    11041 ctgcaattcc tgctatttta gctattgttc gtgcgatgaa ggaatcaaga gaaagttaag
    11101 cacacattat gagcgtcaaa caaaaaacgc atatacctgc ggtggcaggt tatgcgtttt
    11161 ttgttgtata aagacttttt tcattaacga tttttgatta gccgactccc aaaacaaaat
    11221 ttagcagttt atctgaataa gtgatttctt catctgtttg tttcacactt tcatttagta
    11281 gtcccatctc atcggttatg ataccatcca caccataaaa catcatgcga ctcatggcat
    11341 ctgaatcgtt gattgtccat acatatactt cttttccgtc ttggtgggca gaattaatga
    11401 agttacggtt gatcgtacta tattccattg tcagaaaatc agcaggcgtc acagggggcc
    11461 caacaatatt gaaaggtaag atgtagccca cataaaagtt tggttctgct tcttttaaat
    11521 ctgaaacggt ttggtacgtc aaactttgca aaatatgatg gttctctaag ataactttgc
    11581 ggtatttatg gacaaatcgt tcgacaaggt catccgaatc ttttttagag gtcttgatct
    11641 caataagtaa tttttggttt agcttatgtg ctttttccaa ataagaatca aaagaacaaa
    11701 caggggcttg cactccgttt tcagtaactg taagatttgt caattctttc aatgtaagat
    11761 cctgtggtgt tccatttacc cctgttaagt gacgaagatt tgcatcatgc atcactacga
    11821 aatgaccatc ttttgtttcc tgaacatcca tctctacata atcaggatga tagtctctgc
    11881 ttgttttttc aagtgcttct aaagtatttt gcgccccatt ttgggtactc acacctctgt
    11941 gagagacagt cactggtttt gtctgaacag ctgaagtcag ataatccata ttgtaaagac
    12001 agacgccaat accgaaaaaa actgcaaaaa gagtcaaacc agtgtttttc agcgcagaga
    12061 aacgcaagtt gggggcttgt gggataaacc acttagggat ctcaggcaag aagccttcgt
    12121 catccatgaa atcaacaatg atataaaaaa tccctacggt agacatcacg atattgaata
    12181 ataaaatccc ttgtaaaagc gtcatagcaa acacagcgct gatcaatgca tagtctggga
    12241 aaaattgttc aaccatactt tgtgccaaaa taacaacgat atatcctaaa gaagaaagga
    12301 gtaaaatcgt accgccaatc acaataaatt ggcccgtgat ggccaaaaga cgcgatttgg
    12361 tcaatgacca gctttcccga atggctgctc gaaaagaacg atctcgtaga atcatttccg
    12421 gtaaagcaaa aatcagtcga atcccaatat agccaaggaa aatataaacg agtaaaaagg
    12481 aactgacgat gatccaacga ttagcaaaaa taaaatccat aatgaaagcg gggattttta
    12541 tttttgacag tagatcagaa ttaaaactta atccgctgat cggtagaatc aataaaaaat
    12601 aagcaaggaa aaacaaaaaa gtaatgggtc tcactttctt cagctgaagt atcgtcaagt
    12661 gtaagagttg cttcaaagag attggttctt tctttttaat aaaaaaaaca ctcatcaaaa
    12721 gaaaagtaaa ttcgaaataa actaacagta aaatcgtcat caaaactacg attaacgaga
    12781 gtagaacccc aggatgttga gaaaaaattg aaggaatatt gtcataagac aaatagtcaa
    12841 ttgcccctcg gtgtaaaata aaacgggtcg tactgctcaa taagggtaaa caaataaata
    12901 aaataaagcc atgcatcagc aagacatcac ggaaataagc ttgtgttcct tttaaaaagt
    12961 cccaagcatt acctaagcta cgtttcaaat aattcatcct atcacctgct cttcacattg
    13021 tagcgcaaat ctaatgaaaa aggaaagggt gcagtgtgtt ttgcagaccc tttcccagat
    13081 tta
//
LOCUS       DADGKS010000074        12738 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.075, whole genome shotgun sequence.
ACCESSION   DADGKS010000074 DADGKS010000000
VERSION     DADGKS010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.075"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            97..540
                     /locus_tag="JXV47_002321"
     CDS             97..540
                     /locus_tag="JXV47_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAX1488336.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(546..1730)
                     /locus_tag="JXV47_002322"
     CDS             complement(546..1730)
                     /locus_tag="JXV47_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HAX1488337.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            1998..2696
                     /locus_tag="JXV47_002323"
     CDS             1998..2696
                     /locus_tag="JXV47_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HAX1488338.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2703..3380
                     /gene="nth"
                     /locus_tag="JXV47_002324"
     CDS             2703..3380
                     /gene="nth"
                     /locus_tag="JXV47_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HAX1488339.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3506..4039)
                     /locus_tag="JXV47_002325"
     CDS             complement(3506..4039)
                     /locus_tag="JXV47_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488340.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4336..6717)
                     /locus_tag="JXV47_002326"
     CDS             complement(4336..6717)
                     /locus_tag="JXV47_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAX1488341.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6707..7354)
                     /gene="recU"
                     /locus_tag="JXV47_002327"
     CDS             complement(6707..7354)
                     /gene="recU"
                     /locus_tag="JXV47_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HAX1488342.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7418..7957
                     /locus_tag="JXV47_002328"
     CDS             7418..7957
                     /locus_tag="JXV47_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HAX1488343.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8047..8466
                     /gene="gpsB"
                     /locus_tag="JXV47_002329"
     CDS             8047..8466
                     /gene="gpsB"
                     /locus_tag="JXV47_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HAX1488344.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8488..8855
                     /gene="rnpB"
                     /locus_tag="JXV47_002330"
     ncRNA           8488..8855
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="JXV47_002330"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9064..10230
                     /locus_tag="JXV47_002331"
     CDS             9064..10230
                     /locus_tag="JXV47_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HAX1488345.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10276..11772
                     /locus_tag="JXV47_002332"
     CDS             10276..11772
                     /locus_tag="JXV47_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HAX1488346.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11853..12536
                     /locus_tag="JXV47_002333"
     CDS             11853..12536
                     /locus_tag="JXV47_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAX1488347.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
BASE COUNT         4273 a         2230 c         2630 g         3605 t
ORIGIN      
        1 tcttggtttc agattgggtt ttcctacaaa atatttttat ctttgttgaa taggaaacaa
       61 aaaaacaata taatgaaaga aaaagaaggt gtagaaatgg ataaaagaca actgctaata
      121 gaagaatatc tggatttagc taatgagatt attcatcgta ataaaccaga aatggaaaaa
      181 gaatttgcag gatttactct aaatgaacta gaagtgattg aacatatcgg gaaaatccct
      241 gatcctaacg tgacaaaatt agcgaatgct agttacatga ctagaggagc catcagtaag
      301 ctaacaaaaa aactgatagc tagagggatc ataaacactt atcaaagcga agagaataaa
      361 aaagaaatct attttcaatt gacgccaatc ggacaaaaaa taaggaatag acacgagcaa
      421 ctccatcaaa aatgggtaca gcgagatgct actgtatttg aaaatatgtc aaaagaagaa
      481 tttgacacag tatttcgttt tatcggtcga tacagagaat ttatacgaag tagcaaatga
      541 agctactatt ttttattgta gtgataatag gcaaaaatca taagcaaaaa tccgaatacc
      601 gtcggaagaa atggtgctgc agcataaagc tgtcctgcga ttagcgggcc gatgacgcgc
      661 gatagagatt gtatactttg ggtaccgccc attacaagac cttgctggtt atctgagaca
      721 gaattggata gttggccatt gaatacagga gtaaaaatag aatcaccgaa accataacag
      781 ataatcccaa ataaaaacaa aatcggcagt agaagaattc cagataatgt gatgaataga
      841 taggcgagga tttcactgaa catccctatt cttgtgatct gctgttctga aaattttttg
      901 agcaatcgag gcataatgaa caattgcgag acagtatcca agattccaat caaagagaag
      961 cttaaaccaa ccaacccagc cttccactga aaggcgtcaa tcgaaaattg agaaaagata
     1021 gattgaagag agccagctgc caaccaaaca gcaaaacctg ctgtcaataa aggaataacg
     1081 gatgaaatct tgaataattg ttgtaattgg tgaaaaggtc ttacatggga gaaacttaaa
     1141 tctactgaac gtttttttat tggaaggctt tctagcataa atgtgtagcc ataaacggca
     1201 tttaagaaag taaagagtgc tccaataaat ataggaacag aattccccaa ctcagctaat
     1261 agacccccta taataggacc cagcgttgtt cctataccga ctaaagcacc catccatcca
     1321 aaaactttgg ttctttcatt aggttccgtg atgtcggcaa agtaagcata taaggtggag
     1381 atttctcctg ccgtcaatcc ttcaatgata cgaccaagga acaacatcca tatcgaattt
     1441 cctaaaccaa aaagcaaata tccgatactt gatcctaata aactgataat aaggatcgga
     1501 tgacgcccaa aatgatcact taagctaccg agaatggggg cagataagaa ggcagctaga
     1561 gcataaacag acatgagcaa agtgatatag aaagcttgct gatgtatgga gtgagaataa
     1621 ggcagcgtta aaaacggaag tacaggactg acgatagtaa atcctaatcc agtgaataag
     1681 acagagacgt atccaaaaac tttagaatgt ttatttgtga aactgtacat gtaaaaactc
     1741 ctttatgcaa taatgttaac ttggaaacaa aaatagtgta tagtaatttt gtttccttgt
     1801 caacattcta aggaacagcg aaatctactt aatttattta ttccgaaaag tgaagatacg
     1861 catcaaaaac atgaacaaac aaaaatcaag tagacgacat tgtaaatctg accgatcagt
     1921 gaagtaaata gaaaagaaac ctgttcttgc ttcccatgtt ttttttacgt atactgtgat
     1981 tgagcggagg agaaatcatg ttgaatttag aaaattactt aagcgctgga caaacagtca
     2041 tatctaatct tttacttaaa aattatcata ggatcggtct acaatctgaa gaatttttat
     2101 ttgttctaca gttgcatatg gcacagcttg aaggagatac tttccctgat ttgcagatga
     2161 ttgctatgga tatgggaatc aaacaagatc agatttttca aatactggat cgtctcgtaa
     2221 caaatggatt tatcaagata gaaacgacga ttgtcaacgg taaaaaagca gatcgatata
     2281 atctttaccc catctatgat ctattaggtg agtatttaaa aacacaagaa aaaaaatacg
     2341 aagaaaaaac acaagaaaaa gaaatccagt cagtgtatca attatttgaa caagaatttg
     2401 gacgcccgct ttcttcgatc gagttccagc ggatcggaca atggctagaa gaagaccatt
     2461 atcagccgga aattttgaag ctagcactgc gggaagccgt attaaatcag gcttatagtt
     2521 ttaattacgt tgaccgcatt ttgctatcgt gggaaagaaa aaatctacgt acaaaacaac
     2581 aagtggaaga agaccaaaaa cgaagaaaac agcagcttct tcaaagagaa gtagaacagt
     2641 cagctcaaca agaagaattg ccgaaagtct cactgaaaaa ttggttggag gagtagcgga
     2701 atatgttaag caaacaaaaa acaatggaag ctctagaaac gatgtatgga atgtttcccg
     2761 aagcacatgg agaactcaag cacaataatc catttgagtt attgattgca gtgatcttaa
     2821 gtgcccaggc gacagatgta tcagtgaata aagcaacgcc agatttgttt gcctcttttc
     2881 cgacacccga tgcgttagca gaagcttcaa tcgatgaaat cattcttaaa ataaaaacga
     2941 ttggtttgta tcgaaataaa gcaaaaaaca tcaaagcgtg tgcacagcag ctgattgaac
     3001 gtttcgatgg gcaagtgcca acgtcaagag aagaattgat gtctcttcct ggtgtaggca
     3061 gaaagacagc aaatgtcgta ttgggggatg cattcgggat accagcaatc gcagtagata
     3121 cccacgtgga acgtgtctca aaacgcctga ggatctgcaa actagatgct acggtcatgg
     3181 aagtagaaga aacactgatg cggaaagtac cacaagaatt atgggtaaag acacatcata
     3241 cactgatttt ttttggtaga tatcattgca cggcaagaaa tcccaagtgc gaggtatgtc
     3301 ctttgctatc aatatgtcaa gatgggaaaa atcggatgcg tctaaaagaa aaggcgctaa
     3361 aaaagaaacc acgcctgtag acgtggtttc tttaattgca aataaatgta tgaattatct
     3421 tgttattatg gagaaaagct gtttcgttta tcttttttgc atgaaaaagt aaatgtacat
     3481 actcagtagc taggatggta acttattaca atttattgcg ataaaaataa aagttgttat
     3541 ttttattggg aaaatacccg atgtagaaaa taatgccttc caatatacct ataaaataag
     3601 tccagtattc caaaggatta tataaataag tgacgtatct atctaaaggt gtaataaaaa
     3661 tgataagtga taataaaaaa ataccattta taactaaaca taaactaatg gatttgggcg
     3721 gtttcaggct catcagaaaa atatagattc tggtgaacaa caaccataaa aaagtgagaa
     3781 tcattgcatg agagcttctt tccataaatt ttcctttaag agtagtgctt aaaagtacag
     3841 aaaaaataat aaatgcaagg ataggagcaa ttaaagtaaa tttatttaat aataaacaaa
     3901 atttttcagc ttttttattc ttggaataac gaggtattgt tttcgataaa aaaagatggt
     3961 gcagacaaat tatgataatt aagcatacta tcagataact caaaatgaag ccttctttca
     4021 aaaaattatt caaaaccata tattgtattt tttatttgat aataacaatg ggattattaa
     4081 gaagtggcac taaataaaag actagtgtgt atttagccga tttaattata aacaagtaaa
     4141 tggataaagt atatgtaatg ataaaagaaa aatggatttt ctaattttta agctaaatgt
     4201 tagatcacac atgtatatgc tggatagtct tataaaaaat catgtaatac agcttggtac
     4261 atgattttta tttgtagctg ttttttacat agacacaaaa aagaaaccac gcttgtagac
     4321 gtggtttctt ttttactatc tgtttccaga agctgaggtg ctgctggatg gtgtatggtc
     4381 atttgcagca tccgctccgc tagttgctgg ctcactggaa gaagcaggag gagcagatga
     4441 agacggtgtc gagctttctt cggatgaaga agaaggaacc gttgttgaag acgctggctc
     4501 gcttgtttct gctgtcgtgc tttcttttga ggactcagca gttgattcgc tttgactagt
     4561 agagctagag ctttgagtcg ttgtctctgt tgttgagctt ccaggagtct ggacatagct
     4621 ggaagatgga atagttgttg atggtgtaat tgcattcgat ctagctgtat attgatcttt
     4681 gtagtacagt tcaccgccca cacgaattaa tccgcttggc atctcccagt ctgtatttgt
     4741 cacgttagct gaaacatact gcataagctc gcgataaaca tcagaggcta cgtgtgacga
     4801 ttctgaagtg acaggcgtca tttttttatt gtaacctgtc cacacggaaa tcgaataatt
     4861 tggcgtatag cccgcaaata ggatatctgg atacacccca gaagaaatac caagttttgc
     4921 atactcgtca tctgtgtaat tggatgttcc ggtcttaccg gcttgatata acccagcgat
     4981 ttgcgcattc gtaccagttc cttcagtgat cgtatctttt aaaatgtctg tgatcatata
     5041 agctgtttct ggagacatgg ctgtttttcc atctggctca taagtttctt ctgttccgtc
     5101 ttggaagacg attttattaa catattgagg tttgtaataa gtccctccat tggcgaaagc
     5161 cgcataggct gctgccattt ttaaggaaga agctccgtat tttgtcccat cttgttcttc
     5221 cgtattacta gagatcgcat tcgattgatg gatcgtactg tattcgatcc caagattttt
     5281 taagaaagaa gccactttat ctgaaccgac ttcattgaat aatttgactg ctggaacatt
     5341 acgggataag taaagtgctt ggcgtaaagt aatggtgccc atatattgat tatcccagtt
     5401 tcctacagga gtcgaagtcc cttcatagtt atacggtgcg tcagtaatag tttttccagt
     5461 agaatatttc aaatattcaa aagctggtcc gtaatctgtg acaggtttca tcgtagaacc
     5521 aaaatcacgg gaagtattca ctgctaagtt gttgcctaaa gttacgtctt ctgcgatgtg
     5581 acgtccgcca atctgggctt ttactttccc ggtattggtg tcgataaggg tggaggcaac
     5641 ttgcatctcg tcgtctgggt aagagacata ctgatccgtg ttgacgatat catatagttt
     5701 cttttgggcg tccagatcca aattcgtata aatctctaaa ccgtctgtgt agacattctt
     5761 atctgttttt tcttgtactt cattgatgac ttctttgaca taattatcga cgatcttagt
     5821 attgtcatcg gattgagtta gttcttgcag accatccgtt accggtacat taacagcttg
     5881 atcatattct gtttgagaga ttttttcgtt ttgaagcatc gtatacaaaa cagtatctcg
     5941 tcttttcttc gcctgatctg gataaacata aggatcatag gcggaagggg cttgaggcat
     6001 cccagcaagc aatgctgttt gcggtaaaga aagttctgat aatttcttac caaagtacat
     6061 ctcagaagct gtctccatcc cgtacaagcc gtttgacata tacactttat ttacgtagta
     6121 ggtcaagatc tcttgtttcg attttttttg ttccaatctt acagccatcc acgcttcttg
     6181 ggccttgcgt ttcagagtct gatcctcggc actggtggag aagaaggaaa gtttgatcaa
     6241 ttgctgtgtc aaagtacttc cgccttgcag tccgccagag gtaaagttag agagggcaga
     6301 accgatgatc cgaatagggt caaccccgat gtgtttataa aaacggcgat cttctaccga
     6361 cacgatcgca tcttctaatg ttttcggtaa ttcattcgca gaaatttttt cacgcttttc
     6421 tgcgcctaaa tcttcgaata gttcgccatc ttgtgtatat agtttggaag atacggtagc
     6481 gtctaatttt ttatccgtca attcgggcgc atcttttgcg taataccaga aaagtcctac
     6541 acctgctaaa aagaggatac agaaaaatga gagtattcct aaaaggatct tgataaataa
     6601 tcctttttta tgtgttccag aggactttcc agaacctttg ccagaattct tcttcacact
     6661 ctttttagga gtaggctgtt tctgtcgtct agagcttcta gtttgttcat ttgccattct
     6721 tgctttctcc ttcaatagat aatgttgata aatagaagtc aaccgcgtcc aaataaggaa
     6781 tccgcggaga aataccagtt ttgatctcta ttcctagttc ttcgatcaaa gataaaggta
     6841 gtgatttgcg tcctttttcc ttttgggcgt cccagtaagc aatcaaatga acactattca
     6901 aataaaaaca gcgcttcaaa gacgaaaacc ataacaagac aaagcagacc ccattttgtt
     6961 cgaggcatgc tttcatatgt tcgatttgat gggcatggaa gtttttaaag ggaaaagatg
     7021 ttttgttctt ggtttctttt gcttcaaagt ccaagtaaaa gcctcgatag acgccattat
     7081 agtctgtagt tgaggcttgg gtaaagtagg cttccttgat cacagcagca cttctcttag
     7141 gatagtctac tttcacgatt tggatagggg taggcttttt atggataacc gccaacccgc
     7201 gggaaagata atatttatta ctttcattga ttgcttcttc aaagcgcatc ccccgattgc
     7261 cgaattcagt gatctgattt cttttttctt gaattttttc gacgggagag gcattcttat
     7321 aataaggttg gccatttgga tagcgcaata ccatctttaa tcacactcct aggccacatt
     7381 atagcaaaaa agcggataga aagaaaagga atctgagatg gataagtcaa aagtaatcta
     7441 tgtgtctggg tatcgaagtt tcgaactcgg tgtttttaaa gaaaatgatc ctaaaatcca
     7501 agttgttaaa aatgttttaa aaaaagaact ccatcagtta gcagaagaag ggctggaatg
     7561 ggtacttgtc agtgggaatt tgggcgtcga actatgggct gtgcaaatag tagcggaatt
     7621 gaaagaagaa tatccggaac tatctcttgg tattttgtat cctttttctg attttggtaa
     7681 taactggaat gaagggaacc aagaaaaaaa acaattagca gaacaattag cagattatgt
     7741 cgaagctgtt agccatcaac cctaccaatc acctagtcag ctaaagaatc acactcgttt
     7801 tatacttgag catacagtgg gctgtctgct gatctatgat gaagaattcc ctggaaaaac
     7861 gaagtatttt tttgaagatg cacagaatta ccaagcagat catccctacg aaattcggct
     7921 gatcagtatg gacgatcttc aaaattttag tgaataatcg atattgtgtt tgatttatca
     7981 acttttttcc tatacaatga aaaaggtaga aatgttatta cgtaaatgaa aactagaggt
     8041 gtaaatatgg cgaatttggt ttatagtcct aaagacattt tacaacaaga attcaaaaca
     8101 aaaatgcgcg gctatgatcc cgttgaagtt gatgaattct tagacaatat catcaaagat
     8161 tatgaaactt acagcaaaga actccttgct ttacaagaag aaaacgatcg attgagtgca
     8221 aaagtagctc aattatctaa aactcaagga gcagctcaaa cacgcgtgca acaaacagag
     8281 gcaccaaaga gcgcagcagt gaccaatttt gatatcttaa aacgcttgtc aaatcttgaa
     8341 cgtgaagtat ttggtaaaaa gcttgatcaa caagcaagtg cagtcaaacc agcacaacct
     8401 aatccaaata actacacaaa tgcagacaca agcttagatg ataatgaaaa aacacgtcaa
     8461 ttttaatttt tgattaatga atttgcggtt ttcgggtaat cgcggtctga cttgatcagg
     8521 ctgaggaaag tccatgctcg cacaggctgt gatgcctgta gtgttcgtgc ttagcgaaac
     8581 cataagctaa ggtactcttt ggagtaacgg caggaaaaca agctaaggct tcggctatgc
     8641 ttaagtatcc ttgaaagtgc cacagtgacg aagcggctgg ggaaacccat ccggtggaac
     8701 gcggtaaacc cctcgagcga gcaacccaaa caatggtagg ggcgcttttt gtctggaaga
     8761 agaacaggac aaaaaggcag tataactgca gatagatggt taccgctttg ttttttctcc
     8821 ctggaaaagc aaagtacaga acatggctta tagaaaaccg caaacatcag ggaattaggt
     8881 cgtgacaaaa gtaatgcgtt ataagaaaca agaaaaacat ttgaaagcta tttttcaata
     8941 cttcagatga atcgttctta ttacaaaaca aacttttgta tcaccggtta ttcggaattt
     9001 gagtaaaagt gtggggtagg actgatgtcc cacctccttt ttttataaat aaggagattg
     9061 tgtatggaaa aaaacaggaa gttcaacctc gtcgcaactg cggcaagcgg gctagaagca
     9121 ctggttggta aagaattaag agatcttgga atcgaatgcc aagttgagaa cggacgtgca
     9181 cgttttgaag gaacaatgga aacgatcgct acagctaatt tatggttacg tacagcagat
     9241 cgagtaaaaa tcgtggttgg ggaattcgat gcgtatacgt ttgatgaatt gtttgaaaac
     9301 gtaaaagcat tgccttggga agattttctt ccactagatg cagcttttcc tgtagctgga
     9361 aaatcgatca agtcgaaact atatagcaca cctgattgcc aagcgatcac aaaaaaagca
     9421 atcgttgaac gtctccgtac ctattatcac cgtccagctt ctgtaccact gacggaaact
     9481 ggcgcacatt ttcagttgga agtagctttg ctgaaagacc atgtgatggt aactctggat
     9541 acgacaggac caagtttatt caaacgtggt tatcgcttag aaaaaggtgg agcaccattg
     9601 aaagaaaaca tggcagcagc acttattatg ttgacaaatt ggcgaaaaga ccgtccattt
     9661 tatgatcctg tatgtggttc aggtacgctt tgtattgaag cagccttaat aggccataat
     9721 atcgcaccag gattcaatcg tgagtttgct tgcgaatctt gggattggtt cagtcaagaa
     9781 atcatggaaa atgttcgatc agcagccgaa gaaaaagcag attatgatat tgaattagat
     9841 attactggtt cagatatcaa tggacggatg attgaaattg ccaaagccaa tgcagaagaa
     9901 atcggattag gctcttcgat tacctttaag caacaagcag tcaaagactt caaaacggat
     9961 aaagaatacg gggtcatcgt ggctaatccg ccttacggag aacgtctagg agaagaagaa
    10021 actgttcgga aattatataa agaaatgggc gatgtattcc gtccattaaa aacatggagt
    10081 aaatatatct tgactagcga cttagcgttt gaggaatttt acggacaaaa agcaaccaaa
    10141 aaaagaaaat tgtacaatgg tgcattgcgt acggatctat tccagtattg gggaactcgt
    10201 ccgcctagaa aaaaagagaa agacgaataa tcttactaat tgattcattc aattggatgt
    10261 ttggaggaat agggaatgaa agaaaaagag tttttacaag aagtaaaaga aatcaatctt
    10321 ctacaacaag ctttaggaat cctcgattgg gatacacaaa caggtatgcc tgaaaaagct
    10381 agtgcatacc gaagtgaagt agacagctat ctttacagca tttatttttc aaaaaaaatc
    10441 ggtccaaaaa tcaaagaagc cattcgctat ttttctgaac atccggaaga attgtcggaa
    10501 gttggaactg ccgtttttgc caaagtaaaa gaagagtatg atttggaaca tcgcgtaccg
    10561 gaagatctta tgagaaaata tacagctgcc gtttcttcag cacacggaca atggcaaaaa
    10621 gctagagaaa cacaacaatt ttctgatttt caacacgcat tgaatcaaaa tattgaatta
    10681 acaaaacagt tgatacctta ctggagaaaa gatgaaaaga cgaattatga tgttttgctg
    10741 aatcaatacg aacccgggat gactgtcgaa atccttgata aggtatttga tcagcttaaa
    10801 gaaggaattc tttcgatccg ccgtacgctc caagaaaaag ggactgaacc tgaaacagac
    10861 tttttaaatc ggagaatgac gaaaaaacaa cagaagagat ttgtagtgaa agtaatcgaa
    10921 caacttggtt atgattttag tcgtggtcgt ttagatgaca ctgtccaccc atttatgact
    10981 ggaattaatc cgaatgatgc acgaatcacg acacgatgga acgaaacaga tttcaaaatg
    11041 gctgtttttg gagtgatcca cgaggctggt catggtatgt atgaacaaga catcgatgat
    11101 aaatatgcgt atacaccggt ttatgaaggt acatcaatgg gtatccatga atcacaatcg
    11161 ttgtttaacg agatcattat tggaagtagt cgcagcttct ggaaaaagca atatcctttc
    11221 tttcaagaat gtgcagaagg aacattcgat gatattcctt ttgacaaatt ttatcgttca
    11281 ttgaaccata caaaatcaag tttggttcgt atcgaggcag acagtttgac ttaccctctc
    11341 catatcatca ttcgttatga aatcgaaaaa atgattttca atgaaggggt agatgttgct
    11401 gaactacctg aaatatggaa tcaaaaatat gaagagtatc tgggaatacg accaacaaat
    11461 gatgtggaag gcatcctaca agacgttcat tggtcaggtg caagctttgg ttattttccc
    11521 tcttatgcat tagggtacat gtatgcggca caattacttc attctttgca gcaagaaata
    11581 gatgtggaaa atgttctagc gtcagacgat tattctccaa tcaaaaactg gatgtcagag
    11641 catatccatc aatatggtgc atctagaaaa ccaaatcaat taatcatgga tgcaacacat
    11701 gaaccgctta atccgcaata cctgatcgac tatatgaaag acctgtattt taatgtatat
    11761 caggtaaaat aaaatacaat ttacaaagat agctgaaatt catctaatct atagatgttt
    11821 tcagctattt acttaagaaa gaagtggaac gaatggataa attacaagtg atcgctgatt
    11881 atagtatgga ccaattagcg catgatcaaa caggacatgg gagcgatcat accaaaagag
    11941 ttgtcaagtt agctgaaaaa attttggaga cggaaccgca ggcagaccgc tttgtgacgc
    12001 ttgcagcagc ttacctacat gatacgattg atgataaagt cgttaaaaat gagaacgagg
    12061 caaagcaaca gcttcgtgta ttccttcgct ctttgccaat agtagaggaa cagatctcga
    12121 tgattttttc cattatcgaa aatatgtcct tttctaaaaa tctctctgaa gcggccgaac
    12181 tatctctgga aggtaagatc gttcaagacg ctgatcgtat cgaagcatta ggagcaatcg
    12241 gcattttgcg tactgcttat ttcggcggtg gacatgggca cccgattttt gatcctgaac
    12301 tgtatccgca aacattcaag gacaaagaaa attaccgaaa aggcacgaca gtgatcaatc
    12361 atttttatga aaaactgttc ttgctgtctg ataaaatgaa tactgattac ggatatgaag
    12421 aagccaaacg aagagaaacc ttcatgcgtg aattcttaga agaatttttt ctggaatggt
    12481 ctattgacga tgaaaatttt actccagaca attggatcaa aaataacaaa aaatgatgga
    12541 ggttgtgaca gaagtggtca gctccaagat atttcggatc attttccgta aaagttactt
    12601 ctggaacact gtttaccaag aggtcgtgag cctgccgttc agctccgagt cacaaggaac
    12661 aatttcaaaa aatagcttct cgtgtttgat gaatattgta acttgtgatt cggaattggc
    12721 aggagaacac cgtttatt
//
LOCUS       DADGKS010000075        12734 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.076, whole genome shotgun sequence.
ACCESSION   DADGKS010000075 DADGKS010000000
VERSION     DADGKS010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.076"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(86..265)
                     /gene="rpmF"
                     /locus_tag="JXV47_002334"
     CDS             complement(86..265)
                     /gene="rpmF"
                     /locus_tag="JXV47_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAX1488348.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(323..892)
                     /locus_tag="JXV47_002335"
     CDS             complement(323..892)
                     /locus_tag="JXV47_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HAX1488349.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1078..1980
                     /locus_tag="JXV47_002336"
     CDS             1078..1980
                     /locus_tag="JXV47_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAX1488350.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="JXV47_002337"
     CDS             complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="JXV47_002337"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HAX1488351.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="JXV47_002338"
     CDS             complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="JXV47_002338"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HAX1488352.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="JXV47_002339"
     CDS             complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="JXV47_002339"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HAX1488353.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8548..8733
                     /locus_tag="JXV47_002340"
     CDS             8548..8733
                     /locus_tag="JXV47_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HAX1488354.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8795..9991)
                     /locus_tag="JXV47_002341"
     CDS             complement(8795..9991)
                     /locus_tag="JXV47_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAX1488355.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10161..11597)
                     /locus_tag="JXV47_002342"
     CDS             complement(10161..11597)
                     /locus_tag="JXV47_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAX1488356.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11890..12699
                     /locus_tag="JXV47_002343"
     CDS             11890..12699
                     /locus_tag="JXV47_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAX1488357.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3801 a         2673 c         2250 g         4010 t
ORIGIN      
        1 tattttttat ttaccgacta caaaaaaata aacctcaagg ctccatggtt agccttgagg
       61 ttttacattt tctaattaaa atgtattaag cttcttttga cattacgtcc ttaccatcat
      121 agtaaccaca atttgcacat acgtgatggc tttttttcat ttcaccacag tttggacatt
      181 cgtttaaccc tttgattgtc aatttgtagt gtgtacgacg ttttgctttt ttagcttttg
      241 atgttcttct agctggtact gccattttgc tacacctcct tgtaaagtct tgtatctaaa
      301 ttagacacaa tatattccaa tcttacttgt tatcgtcgtc ttttgattta gaatcaaaaa
      361 gttcagatag ttttgcaaga cgaggatcaa ttttattctc ggcttcttcc atttttctgc
      421 gctggtattc ttcttcggaa acaacttccc aatcattgcc ttttggaagt tctgttgctg
      481 cttcctcttc ttttgtcaat acccgcattg gaatcgccaa taagatgttg tcttcaatcg
      541 actctgctaa attcaataat ggaccttcaa ttagcaaaat ctcatctgca gacatttgtt
      601 catctctact ttggaattgt tcttctgtca tgaatacttc gtctacagaa aaatccatgg
      661 gcagttcaac aggttctagt gaacgtgttg aaggaactgt caaagtcgtc tgcacagtgt
      721 aatgaacgat atagcctttc ttatcaactg agaccaaacc ttcgacttcc actggcgcaa
      781 catcaagtat taaattgtct cgcttcatga gagcggcttt caagtcgagc gtctcatgaa
      841 aagttaacgg tgtctcctgg tattttctca attccaataa agaccatttc atttttcatc
      901 actcctaagc aacaaaagca attatacagg gcaaaaagca tgttgtcaat gaaattttct
      961 tgacaccttg cagttcataa aaaaacagaa aaatctttat tagaaagcct ctgtttgcta
     1021 tcatcctcag aatcatttac aataatcatt attccattaa aggagcggat gatcttcatg
     1081 aacacgaaag atatcgaata ctatgtccaa atcgtcaaac aaaaaaattt tacgaaagtg
     1141 gctaattatt tccgtgtgag ccaacctact attacatatg cattacaacg tcttgaaaaa
     1201 gagtttgaca ccgtacttat tacaagagat cgatcgcatc acgaattaat cgtcacgcct
     1261 tctggaaagc agctgtttct ccatgcacaa accattctcc aagagatttc tactgcaaga
     1321 gctgaaatca ctcagttgca aaagaaaaag cttcgttttg gcatgcctcc tattatcggc
     1381 aatgaatact ttcctaaact gtcaagttac tttatcaagc atgaattgat gaatcaaatt
     1441 gagattaccg atggaggctc tcgggactta tacgggatga tccgacaagg gaggatcgat
     1501 ttagctgtat taggctcaac acagccaatc gtggatcaat atttagaaac agagttactt
     1561 ttggacaaac gtttcatgat cgtcgtgcca cctacacatc ctctttccaa gcaggatact
     1621 gtctctttca aagatatagc agatgaacag tttgtactat tgaacgaaca ttatgtccac
     1681 cccgcagcat tcactaagct ttctaaacaa acacatactc atccaaaagt tgtttatcaa
     1741 agcaatgact tgacgatttt aaagagtatg gtccgagaaa atgtgggtat cggttttttg
     1801 gcagagattg ctgtccatcc tgaagatcat ttagtttgcc tccctctttc agatgaagtt
     1861 cagcctcgct tcttgatttc attggcaaaa cgaacacagc agatcgtcac gcctcttcaa
     1921 gaacaagtag tccaagttat ccatgaattc gttacagcac aaaaaaacag ctcttcgtaa
     1981 aagaagagct gtttttattt tttattaagc taaattagat agctgttgtt tcgccacggt
     2041 aaacgatgcc gcgacgtgaa tcaacggtaa tcaattcacc ttctgtaatt gttgttgttg
     2101 cgcctttagc accaacgatt acaggaatat cttgtgcaat tcctacaact gcagcgtgag
     2161 aagtcaatcc gccttcttca acgataacag cagctgcttt ttcgattgca ggcatatatt
     2221 ctttgtcagt tgatggtaca actagaacca ttccgtcttt tgcttttttt acagcttctt
     2281 cagcagatga agcaataact gcatttgcaa cgacagattt ttgtccaacg ccttgagctt
     2341 ctaataattt agaaccaatc atttgaattt tcatcacgtt agttgttccg cgttcaccaa
     2401 ctggtacacc agcagtgatc aagattaaat cgccttctga tgcgaaacct aattcaacag
     2461 cttttttagc tgctagttca aacatttcat cagttgttga tggtttttca gcaactgttg
     2521 ggtaaacgcc ccagtttaac atcaaaccac gttttgtgcg ttcgtcaaaa gtaacagcca
     2581 agatatctgc atctggacga tattttgaaa tcatttttgc agtgtatcct gattcagttg
     2641 cagcaacgat tgttttcacg cctagatttt ttgcagcacg agctacagat aaaccgattg
     2701 tttcagttac atctgtttta tcgaattcgt tcaattggaa tgtacctaat tctgataatg
     2761 cattttcagc ttcttggtcg atacgtgcca ttgttgaaac agcttcaact gggtagtccc
     2821 cgtttgcaga ttcaccagat agcattgttg catctgtgcc atcaaataca gcgttagcaa
     2881 cgtcagaagc ttccgcacgt gttggacgtg ggttttcttg cattgattct aacatttgtg
     2941 tagcagtgat aactgggata ccagcagcat tacatttttt gataatgcgt ttttgaacca
     3001 ttggtactag ttcagctggg atttcaacac ccatatctcc gcgggcaatc ataacaccgt
     3061 cagaaacttt gatgatttcg tcaatgttgt cgataccttc ttgagattcg attttaggga
     3121 agatttgaac atgagtcatg tctttttctt ctaagatttc gcggatatct agaacgtctt
     3181 gtgctttacg tacaaaactt gcagcgataa agtcgatatc gttgtctaaa ccaaaacgaa
     3241 tatcgtcagc atcttttgga gtaatacctg gcaaactaat agaaacgcct ggtgcattta
     3301 cccctttacg tgatcctagc atacctgcat ttttaacttc tacgactaat tcacggtttg
     3361 cttcgtcttt ttcaatgatt tgcatatcga tcaaaccatc atcaaataaa atgtgtccgc
     3421 caacgtgaac atcgtcaaat aatcctgggt aagtaaccgc gattttttct tttgaaccta
     3481 catgttcagg atccatagag atgcgtgttt gatctcctac ttcaaatttg atgtatcctg
     3541 cacgaccaaa atcagcttct gttgtgcctt gaacagttgt acggatttca gctccttttg
     3601 tatctaaaag aataccgaca tcttttcctg tctttttaac tgcttcacgg accatagtca
     3661 tacgtgataa ttgttcttca tggtcaccat gagaaaaatt aaagcggaag acatttgccc
     3721 cagattcaat caattgagaa ataatttcta ctgagttact tgctggtcct aatgtactaa
     3781 cgattttggt ttttttcatt taaaaaactc tcccattcaa ttttgtttat ttaaagctgt
     3841 acacagctta aatagcttgg tttctttcac tcttaaaatg aaagtgaatt atttagatca
     3901 tatagtgata agtctggttt atgtttgttg ttttcaagtg tatcaatgat gtcagacgca
     3961 acgatttcgt tgtcatggat accgacacat aatccacctt ttccttcttg aagcaattcg
     4021 acagcgtaag caccgaattt acttgccaac acgcggtcgc gtgcgcttgg tgctccacca
     4081 cggacaacgt gtcccaagat agatacacgt gtatgatagt caccaaattc tgaaagtttc
     4141 tcagcgaatt catttccgcc cattacacct tcagccaaga tgatcaagca atgtttcttc
     4201 ccgcgatcgc ggccttcttg gattttttta gcaactgaag ccatatcaaa atcatgttct
     4261 gggatgatga tttcatccgc tccgccagcc acacctgacc ataaagcgat gtctcctgca
     4321 ttgcgtccca ttacttcgat aacgaatgta cgaacatgag aagtcgctgt gtcacgaata
     4381 cggtcaattg attctagtac tgtattgatt gctgtatcaa aaccgattgt gaaatcagtc
     4441 ccaggaatat cattatcgat tgttccagga atacctactg ctgggaaacc gcgttttgtc
     4501 aaagccattg cgccatgata agagccgtct cctccgataa ccactagacc ttcgattccg
     4561 aattttttca attgttcgat tccttttaat tgaccttctt cagttgcaaa ttctggataa
     4621 cgtgcagaat acaagaatgt accaccacgt tggatcttgt cacctacatc tgccacatca
     4681 agacgacgaa tatctccagc aactaaaccg gcaaaaccat aattgatccc gtatacttcc
     4741 agtccttcgt aaataccttt acgaacaacg gcacgaacag ctgcattcat tccaggtgcg
     4801 tctccgccac tggtcaaaat tccgatgcgt ttcataataa acattcacct cattaaaata
     4861 ctttatccta agtatgactt aggtttacaa ccatttttgc gttaaccacg actaacattc
     4921 taacattatt tttctcactt gtcttgattt acggataaaa aaatgaaaaa aaatgaaagc
     4981 aagtagtatt ttttaccgta agttatttga aaaccacatt atcttcgcca agcagataaa
     5041 taagttgccc ctttatactc ttgctgtcat ccacccaata agcatctgac agaactactt
     5101 ttcgttgcgt tttttcgtga tacataacta ctggtatata tcctgggtgt ttctgaaaaa
     5161 tcacttgtaa ttgtttcatt atctcgggat cttcccgttc ttctgtaata cgcaaatagc
     5221 aagtttgtga aggatactgg gcttctaact ggttaggatc agcaaagctt tctccaatta
     5281 gttgcagttc ctgattatat ttgctgattt cgctccgccc ttgaacaaag atcactcgat
     5341 caacggcaaa caaattacga tatttacgat aaagagttgg aaaaactgtg acagaaattt
     5401 ctccactact gtcggttcct tcaacaaagg ccatcagttc tccttttttt gtccgaattt
     5461 ctctaacttc cttgatcatc actaataaat tgactggttg attagggacg atatctgtaa
     5521 tcagctgaac ttgtttagct aaacgaagac gatcaaaccc ttctgcagga tgacctgaca
     5581 aataaatacc taagtactcc tcttccagct tcaagcgttc ttctagtgta tagtcagcga
     5641 cttcttcttc ttttaatgcc atgattccca gcaagtcaag acttccacca ctgtaaacga
     5701 tattttggat ttttccttcg agatcaagca tcaattgttt cctgttagga gataattcat
     5761 caaaaactcc tactgctgtc agtgattgca gtaactctaa tttcagccaa cgcttatcga
     5821 tccgtatgag gaattgatcc actgactgga acgggccatt ttgttttctt tcgtttaata
     5881 tatcttctac aaaatcacgc cgaatacctt ttatcgctgt cagtccgaat ctgatttctt
     5941 ccttattgac caactcaaaa ctggaattac tttgattaat ggacggcgag gaaagtttga
     6001 gtttattttt acgtgcttct gcaatatatt ctttcaattt tgatgtgtta tgccgaacag
     6061 aattcatcag gctggtaaag aaagcacctg gatgatgggc ttttagatac gccatttgga
     6121 atcccacgaa tgaataagca aatgcatgtg accgattgaa tccatagttt gcaaattttt
     6181 cgatatattc atatacggtc gctgctgttt tttccgaata tccctgttgt aatgctcctg
     6241 atacaaaatg cgacttttct tcatctaata cgtctttttt ctttttactc actgcccgtc
     6301 gcagaatatc tgactgccct aatgtaaatc cagccatagt cgaggcgatc tgcatgattt
     6361 gttcctgata gacgatcact ccatatgtgt ttttcaaaat cgggatcagt gaatcatctg
     6421 ggtagcgaat ggcttctttt cctttcttcc tggcaatgaa ggtatctata ttttgcatag
     6481 ggcctggtcg atacaatgca ttgactgcgg caatatcttc gatgttttct ggatctaatc
     6541 ttcgtaaaac gttccggata ccagcagatt caaattgaaa tactcctgag gtttcgcctc
     6601 gttgaaacaa gagcagcgtt tttgcatcat ttagcgggat ctcttttaat cggatctcat
     6661 acccttctac tcgcttaaca gctttcaaag taaaatcaat aatcgataag ttgcgtagtc
     6721 ctaaaaagtc cattttcaaa agaccgattg cttctacctc attcatcgta tactgggtca
     6781 gaaaagcttc atcagaaccg cgttggagcg gaactagttc aagtagattc ttatcgctga
     6841 taactacacc tgctgcgtga gtcgaaacat gtcttggcaa tccttctaaa atcactgcag
     6901 ttttgaataa aagttggttt ttttcgcttg cctgaactaa ttctactaat tgatgcgaag
     6961 ttttataagc ttgggtcaat gtgattttca attgattggg tattgctttt gaccagcggt
     7021 ttgcttcact ttgcgataaa ccaaacactc tagctgcatc tctaagaacc atttttgctg
     7081 ccattgtgcc aaatgttgcg atttgtgcca tatgatattg tccatacttt tctcgaacat
     7141 aattcaatac ttcttcacgt cgattgtcag gaatatccaa atcgatatct ggcatcgtaa
     7201 agcgttcggg gtttaaaaag cgttcgaaca gcaaatcata ttctaatgga tccacatctg
     7261 tgatttctaa cacataggct actaatgaac ccgcagcaga accacgacct gcaccggtaa
     7321 cgattttgtt tctatgagca aaagccatta catcccatac gatcaagaaa taatcatcga
     7381 atcccatttg atggatgaca gataactcgt agtccaaacg ttcttggtat tcctttgtat
     7441 agtcagtgat tcggcgttcc acttgcgaat agcataactc tcttaaatat tctccagctt
     7501 gttttccatt aggaactgga taatgcggaa gtaatttctg atggaactgg aattcaaatg
     7561 aaatcgattc agctaaacgc tgggcgccta ttacagcttg ggaaagaccc gctttttcga
     7621 atcgtttgat catttcttgt tctgaaagaa gatagacatt tgctgttagt ggtaaagatg
     7681 cagataaatt ttctaaaggt atttggcttc cctctttgat atgtttcatc acttcaagtg
     7741 caaaaagttc ttcttgttgt aaactagcga tgggatgtaa tgcacaaagc gaataatttt
     7801 cttttatcac atactgatac cattcaggca attgatcagg cgtgttttct gtcaagccga
     7861 tataaaaatt tctagtaaaa acattttcaa gtaaaaactg ccaatgaccg aaaaagttat
     7921 cctctttatt gaaagcctca gaaacagaat gatttgccgg aacaacaaac gctagatggt
     7981 cggtttctgt catttctgca agttccaatt tttcttggat catttttcgg ctggaaagtt
     8041 tcatcagctg ctgataacct atttcatctt ttgcgtacgc aagcaagcca taattttttt
     8101 cttcataagt ataactaaga tgtaatccaa tgattggctg tactccttct tctacacaaa
     8161 tacgatagaa ttcaggtgca ccgtataaga catctttatc cgttatggct aatgaagtgt
     8221 agccttgttt ttttgcttct tgtacatatt ctcgaatacg tatcgtactt tgtaaaagag
     8281 aataagaagt aattgtataa agttgtggga aaaacatctt gcattccgcc ttttttttcg
     8341 ttaaaattca ctagcgttaa aaggtttgat ccttttactt tcattaagat agcaggcgct
     8401 gaagttgatt attccacttc atttgcttgc ttgtaatctg taggaatgag ttctttcgca
     8461 agaactcaaa ttttattgag atttggtctc gtttctttac attcaaagaa aatctggtaa
     8521 aattaagata gaaaagaggt gttctttatg cgatatatcg ttacattatt ctgggctgtc
     8581 gttctaggtc aagtagtcgg ttatattggt gctgcattaa caagcggaac atatgatttt
     8641 actttgacaa caatcatttc attcattgcg ggtgtcatta tccttttgat tggtgcagtt
     8701 gcgccaagaa aagaaacctc tgcccattcg taaaaaaaca gccaagagct tgagatttct
     8761 caagctcttt tttattttct actcctcacc accattataa tctgctgcga agaactttac
     8821 gaaagttgaa taaagaaaga agaatatttg acagaacaaa caaacttgtc acaataaaaa
     8881 cagcactgta attataagca tgcgcgactg tcgatcctag catgggacct aaaacttgtc
     8941 caaagttgct aaacatctga ttgtagctat agattcggct gactccttct tgaggcgtaa
     9001 tcttactgat cagtgtattg acagaaggca tcaaagcgcc agttgaaaag cctaaaataa
     9061 agcgaagtat acctaattgg agcggtgtag tgacgaatgc cataggtaaa taacagcaaa
     9121 atgataaaat gagtcctcca attagaactt tttgattccc aatcttatcc cctagttttc
     9181 ctagtttcgg tgaagaaaag acagcggaaa caccagctat cgaaacaatc aagccgctga
     9241 caaaaaggat attttctgta cttccgctca attcacgaat atataaggtc aaaatagggc
     9301 tgatcgtagt gattcctatc tgtaaaatca aggtcgtaat gaagagaccg atcaaaatag
     9361 agagatgatc catttttgaa aaaatttctt tggtgcttat cagatctttt ttctcgattg
     9421 gatggaaatc ttctttgact aagaaaatgg tcaataccgt tgtgatcatc aacaaagccc
     9481 ctgtgatcaa gaatacattt tccataccaa accactgagc cagtgcaccg cccattgaag
     9541 gtccgatcag atttccagca atcgctccgg tagacaatgt tcctaacgcc catccgctct
     9601 tttctctagg tgcctgtgaa gcaatcatcg ctgtggcatt tggaatatat ccagacaaaa
     9661 tcccattcca aaaccgcatg atcaaaagcc aatacgcgtt tggtacaaaa gccaaagatc
     9721 ccattgttaa tgtcatccct gctgctgcac ggatcatcat gagttttcgg ccttttcgat
     9781 cagctagatt tccccagatt ggtgcaacca cggcagatgc aaaagcagtc acagagattg
     9841 ctagtcccga aaacaattcg atttgatctt ttggtgttcc tagttgctca acataaactg
     9901 gtatgaatgg cataactaaa ctaatacttg caccagtgaa aaaacagcca atccacgcaa
     9961 tcactaaatt ttttctccaa ttaatctcca tctatcatcc ctctttcgtc tcttttatca
    10021 tacctatttt cgaataaaca agcaacgatc tcgccagtaa aaagagaaaa atcccgcaaa
    10081 ggtcatttta tatgtaacgt tctttttatg taaaacaaaa agagatcaga acaaatactg
    10141 ttccaatccc ttctctttag ttaaattgtt gctagaatga tgaagttgat aatgaataaa
    10201 atatcaacga tccacaaagc aacagaaact tgattgtatt ttcctttgat tactttcaca
    10261 attgtataga aaataaatcc tgctgcaatc ccataggaaa tgctatagca caatcccata
    10321 aagatcgatg caaagaaggc cggtaaagct tcttccatat ctagccattt gatgtctgca
    10381 aaagaagcca tcatcattac tccaactaaa atcaatgctg gcgcagttgc ttgatttggt
    10441 acaatggcga tcagtggaga gaataaacta cttaatgcga atagcactgc cactactact
    10501 gaagtcaaac cagtacgtcc accggccccg atcccagctg cagattcgac ataagttgtt
    10561 gtattcgatg taccaaagat agcccccaca gaagtagcga tcgcatcggc aaatagtgct
    10621 ttatccattt ttgttttgaa cccacgacca tcttccaacg cgatctcgtc ttcttttgag
    10681 aaaatacctg tgcggcgtcc tgtaccgata aatgttccga tcgtatcgaa agtatcagat
    10741 aaactgaatg cgatgatcgt catcaatact tgaggaatct tggaagaatc actgaataaa
    10801 gattgcatgc cttcagaacc aaatgctgca ccgaaagttg ttcctaattc tttaaatgaa
    10861 ttacctaacg aattcgtttg ccaatcaatg gaacttaaat caacaacacc cataaaaata
    10921 ccaaggactg tggtcgctac gataccgata agaatagccc cacggacatt ttttacaact
    10981 aaaatggctg tcagtaccaa accaatcaca gccaataaga taggagcgtt gtcaaagttg
    11041 gctaacgcag ggacgattcc accatttatc gtaacatttg tcgcttttcc gccttcaacg
    11101 acagagctcg aaatagctga ctggtctgct gaaaaagata agaatcctgc atttttgatt
    11161 ccgacatacg caacgaaaat accgatcccg ccaccaatcg catgttgaag actttcggga
    11221 atcgcccgaa taatcatttt tcgaatattt gtgacagtaa taaaaatatt gattaatccg
    11281 caaataaaca ccattgccaa ggcttgttgc caagaataac caagcccaaa aacgaccgta
    11341 aaagtgaaaa atgcgttcaa tcccatacca ggtgcctgag catatggtac atttgcgaac
    11401 aatcccatta ccagcgtacc aataatcgat gcaatgattg tcgctagaaa tactgcttgg
    11461 aagggcatac ctgatgctga caaaatcgtc ggatttacga ataagatata actcatggca
    11521 aagaatgtcg ttactcccgc cattatttca gttgatacat ttgtattgtt tttctttaaa
    11581 ccgaaaaact tttccataaa aagttccact ccctgaattt ttttctgatg gaaaactata
    11641 ataataaaaa ataagtaaaa tagggcaaat ccatcgaaca atttcaaatt atatagacgt
    11701 ttcattcgct tttcaacgtt tttttaacaa aaaaagcgaa aataatactt aacgttcgtg
    11761 tttagcttat gtttagctat ttatatagcc ataactgtag tttttgttag gaatagctga
    11821 ttgctcttgt taattaccta aaatatgcta gactaaaaca aatgctagtt gaggaaggaa
    11881 ggacccttat tgaataaaaa attaattgcc atcgatctgg acggaactac cctcaatcaa
    11941 gattcgatga ttacatctaa aacaaaagag actctaaaaa aagcaatcaa tgccggtcat
    12001 catgtcagta ttgctacagg acgcccattc cgaatgagcc atcagtttta ccaacaatta
    12061 gaattaacaa caccgatggt taattttaac ggcgcattag tacacatccc taatcagcac
    12121 tgggatggtg aaagagaaac gttgatcaat cgtgaaatcg cttttgaaat cttatcgcaa
    12181 aaaaagcagc taaatttaga ttttatcgct gctgaaaatc gtgatacttt ttttattgac
    12241 agttttgatt tctttgatga aaaaattttt gcttcttctc gtccaggaga gaagaatttg
    12301 ctttctccta aaaatttgac gacaaatcct acatctttgc ttgtccgaac agacaaacgt
    12361 tttgcaggag ctgtatctgc tgaattaaca cgtcaatttg gcagttatgt cgatgttcgg
    12421 acatggggtg gacctactgc catcttagag attgtttcaa aaggaatcca aaaagcaaaa
    12481 ggcgtgcaag agattgctaa ctacctgtct atcgatcaaa aagacgtcat tgcctttggt
    12541 gacgagcata atgatttgga attgttggat tatgcaggtt ggggagtagc tatggctaac
    12601 ggtactgacc aactcaaagg cattgcaaat gatgtcactc ctttgagcaa tcaggaagac
    12661 ggtttagctg tttatctgga aaaactactt aaactataat agagaattag attccacaaa
    12721 aaagaggttg tgac
//
LOCUS       DADGKS010000076        12522 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.077, whole genome shotgun sequence.
ACCESSION   DADGKS010000076 DADGKS010000000
VERSION     DADGKS010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12522
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.077"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(144..464)
                     /locus_tag="JXV47_002344"
     CDS             complement(144..464)
                     /locus_tag="JXV47_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAX1488358.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(612..2846)
                     /locus_tag="JXV47_002345"
     CDS             complement(612..2846)
                     /locus_tag="JXV47_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAX1488359.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            3325..3591
                     /locus_tag="JXV47_002346"
     CDS             3325..3591
                     /locus_tag="JXV47_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HAX1488360.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            3591..5318
                     /gene="ptsP"
                     /locus_tag="JXV47_002347"
     CDS             3591..5318
                     /gene="ptsP"
                     /locus_tag="JXV47_002347"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HAX1488361.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            5449..6528
                     /locus_tag="JXV47_002348"
     CDS             5449..6528
                     /locus_tag="JXV47_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAX1488362.1"
                     /translation="MLYYISEGGRKVKVLLYFESEKMLAKSGIGRALDHQKRALTEVG
                     ISYTLDEKEDYDILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIRSNQL
                     SPIVKKYLVGLYQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQ
                     KFREYFKLSPDQKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIR
                     KIVKEDHPENVLFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVR
                     DIPVYNGWLEDSKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEE
                     LKNVYESVLNEKVSSKLKKVNQVKD"
     gene            6545..7768
                     /locus_tag="JXV47_002349"
     CDS             6545..7768
                     /locus_tag="JXV47_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAX1488363.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            7857..8744
                     /locus_tag="JXV47_002350"
     CDS             7857..8744
                     /locus_tag="JXV47_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HAX1488364.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            8830..9060
                     /locus_tag="JXV47_002351"
     CDS             8830..9060
                     /locus_tag="JXV47_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HAX1488365.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(9117..10082)
                     /locus_tag="JXV47_002352"
     CDS             complement(9117..10082)
                     /locus_tag="JXV47_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAX1488366.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            10388..10828
                     /locus_tag="JXV47_002353"
     CDS             10388..10828
                     /locus_tag="JXV47_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAX1488367.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            10838..11800
                     /locus_tag="JXV47_002354"
     CDS             10838..11800
                     /locus_tag="JXV47_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HAX1488368.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            11853..12077
                     /locus_tag="JXV47_002355"
     CDS             11853..12077
                     /locus_tag="JXV47_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAX1488369.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            12184..>12522
                     /locus_tag="JXV47_002356"
     CDS             12184..>12522
                     /locus_tag="JXV47_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAX1488370.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKR"
BASE COUNT         4073 a         2168 c         2561 g         3720 t
ORIGIN      
        1 atttgaaaag caattttcgt gaatttcagc ttatttccga aggagttgct tctgctttcg
       61 ccgtttatac gtgtttagag cgtgagacaa aagtgttctt tacttttgtc ccacgctctt
      121 taattattat gttcaaaatt tgtttacacg gctaatgtag cgcctaattc atgttttgga
      181 atcgagattt caacaaggcc tgccaattcg attactttga tttcatcctc gtggtaaacg
      241 gcgtctttga ttttatctaa gaaataattt ttagcatctt cgatttcttt cggctggatt
      301 ttacgtttgt cattgatcag cagaatttca ttatgttcag gggcttcagt gtagacaata
      361 gtggtatttc cggctgtgta gaccttgact agatgggcat cagtgttttc aagctggttt
      421 aatacaagac gggaatggct gtttgttaca tttaccaatt tcatggcgct cacctctttt
      481 atgtattttt aattgcttgt ttctcttatt ataatttctt ttttataaaa tgaacagtat
      541 tttgactttt ctgaaaaaag aatgagacgg catttctcaa agaaataccg tctcacgcta
      601 taaaactgga tttattcagc cgtttcttcg gctgattctt tagccaaacg ttctggttta
      661 gaagtaacga tgatttttcc atctttatcc agttttgctt tcaactcatg gatagaaggg
      721 tgatcaagat aaaattcagc gataccatct tcgatttgtt cttggatcgt gcgtcgaaga
      781 ggacgagcac ccatagatgg atcatagcct aagtcaacta atttttcttt gacattcgta
      841 ggaacttcga tgtgaagttg ctgtgctgcc agcatttggt tgacatcgtc tagcattagt
      901 gtgacgattg tcatcaagtt ttcttttgat aatgcactga attcgatgat cccgtcaaaa
      961 cggttcagaa attctggtgt aaagtagttg tttaattggt tcaatacaga acgagtaaca
     1021 ccttcgcgtg ccgcaccaaa accaacgttt gcttctactt taccagttcc ggcattactt
     1081 gtcataatga tgatcgtatc tttaaagctg accgttcttc cttgtgcatc tgtcaatcga
     1141 ccatcatcta agatttgcaa gaacatatgc aaaacatctg gatgagcttt ttctacttca
     1201 tctaacaaga caagactgta aggatttctc cgtacttttt ctgttaattg accagcttct
     1261 tcgtatccga cataacctgg aggagaacca atcaatttag agacactatg tttttccata
     1321 tattcagaca tatcgaaacg aatcattgaa tcttgtgaac cgaatagttc gtaggcaagt
     1381 tgtttcgcaa gctctgtttt acctacacca gttggtccaa caaataagaa ggagccgatt
     1441 ggacgattct gtttgtttaa tccaacacgg tttcggcgaa tcgctttcgc tactcgatct
     1501 acagcgttat cttgtccgat gacatgagct ttcaagtcat ctgctaagtt tttcagttgt
     1561 gtctgttctt tttcttttaa ttcacccact ggaatacctg tccgttgttc aacgattttt
     1621 tccatatctt tttcggtaat cacaggtgtt tcctcttcag tgagctgacg ttctttcatt
     1681 ttttgaagtt tattgatctg atcgcgataa taagctgctt tttcgaaatc ttcttctcga
     1741 gaagctaaaa ctttttgttc ttctgcttct tgcagttttt tctcgattgt tttaggatca
     1801 acgatttgga tcgtcaagtt tttcttagaa cctgtttcat ctagcaaatc gatggcttta
     1861 tccggcaaga agcgatcttg gacgtaacga ttggataaag ttgcggctgc ttcgatggcc
     1921 tcatcagtat attttacatg atgatagtct tcataacgtt tttgcaaacc tttcaaaata
     1981 ctgatcgttt cttcgacagt tggttcatct acccgtacag gttgcatacg acgttctaaa
     2041 gcagcgtctt tttcgatgat gcggtactca tttaaggtag tagcaccaac catttgcaat
     2101 tctcctcgag ctaaagctgg ttttaaaata ttaccagcat ccatatttcc atcaccagca
     2161 gaaccagcac cgacgatttc gtgaacttca tctatgaata ggatcacatt ttctgcttga
     2221 cggatctctt caatcaattt ttgcatacgt tcttcaaatt gtcctcgtat accagtacct
     2281 tggactaaag atacgacatc taaacgaatg acttctttgt ccattaattt ttgcggtaca
     2341 tcaccatcta cgattttttg tgctaaacct tcaacaactg ctgttttacc aacacctggt
     2401 tctccaatca agacaggatt gttcttggtt cggcgattta aaatttcaat gactcgtttg
     2461 atttcgtcat cgcgtccgat cacaggatcg atatcacctt gtcgtgcttg ttctgtgata
     2521 ttgattccgt attctcccaa taaaccttct gtattgcctt gaggtggctg accaccattg
     2581 aagttgttgt ttccgccaaa ttgtgttggt ggtgtttgct cataatttcc ttgctgttgc
     2641 atttggcgag acatggaacg gaaaagatcg tccaaactgc caaatccaaa tggatcattt
     2701 tgggccatat tagtcagacc tccattttgt tgatttttga ttttttgata acagctctga
     2761 cagtaatcga gttgtgtccg ctgaccattg acagtggcat acaagtgaat cgttgcctca
     2821 ttcttgccgc agttttgaca aagcatgaat cattcacgtc ctttcacaaa aatgggtaca
     2881 tccatatttt acatctcgtt tttcatgagg taaaagaata acccctagtt ttttaagaga
     2941 tttatgaggt agaaaaggtg aaatctctat tgaccattcc tgacctttga ctcttattat
     3001 actaaaaata aaaagggaag caagtaattc gtttcatatg aaaacaaaga gggtcaaagg
     3061 aaagaatgat aaacgtcagg agaagagaaa gcgacaagaa aaaggaaata aacacgtttg
     3121 ttataaaatg tgaagaaaag gatgaaaaag aatccggaat aatttgaata cttttatctg
     3181 aaattgaatg aaaactgttg tatctaacga aaaaaaatgt taatctttac agatgaaagg
     3241 gtggcatttg ttaggattct ctgaattact aaaaaagaaa accctcacat aaaaacaaca
     3301 ctcacttaaa ggagaccgat taatatggaa aagaaagaat ttcacgtagt agcagaaact
     3361 gggatccacg ctcgtccagc tacactatta gtacaaacag caagcaaatt taactctgat
     3421 gtaaacttag agtataaagg taaatcagta aacttgaaat caatcatggg cgttatgtct
     3481 ttaggtgtag gtcaaggttc tgatgttact attactgcag aaggtgctga cgaagctgat
     3541 gcaatggcag caatcgttga aacaatgaag aaagaaggct tatctgaata atggttgaaa
     3601 tgctaaaagg gattgccgct agtgacggtg tagccgttgc aaaagcttac ctgctagttc
     3661 aaccggattt aacattcagt aaggcaacag tagaagatac tgcggctgaa gaagctcgtt
     3721 tggatgctgc attagctaaa tctactgaag aattgcagca aattcgtgaa aaagcagcgc
     3781 aaagcttagg tgaagcagaa gcgcaagtat ttgatgccca tttgatggtt ctttcagatc
     3841 cagaaatggt aggtcaaatc aagcaaaata ttaaagacaa cagcgtaaat gctgaatcag
     3901 cgctaaaaga agtaacggat atgtatatcg gtatgttcga agcaatggaa gataatgctt
     3961 atatgcaaga gcgtgctgca gatattcgtg acgttgctaa acgtatttta gcgcacttat
     4021 taggcgttac tttaccaaat ccatcaatga tcaacgaaga agtggtcgtt gttgcacatg
     4081 acttgactcc aagtgataca gcacaattag atcgcaattt tgtaaaagcg tttgtaacag
     4141 acattggtgg acgtacttca cattctgcta tcatggcacg ttctttagaa attccagcaa
     4201 tcgttgggac aaaagaaatt actgctaaag tcaaagaagg cgatattttg gctgtcaacg
     4261 ggatcgaagg cgatgtaatc atcgatccta cagatgaaca aaaagctgaa tttgaaaaag
     4321 caggtgcaga ttacgcagca caaaaagcag aatgggaaaa attaaaaaat gcagaaactg
     4381 tcacagctga cggcaagcat tttgaattag ctgcaaacat cggaacacca aaagatctag
     4441 ttggtgtcca taataatggt ggagaagcag ttggtctgta ccgtactgaa ttcctgtata
     4501 tggattctcc agacttccca acagaagatg accaatatga agcttacaaa gctgtattag
     4561 aaggtatgga aggaaaacct gtagttgttc gtacaatgga catcggtgga gataaagaac
     4621 taccatatct gcaattacct catgaaatga atccattctt aggatatcgt gcattgcgta
     4681 tcagtttatc tgaacaaggc gacgaaatgt tccgtacaca aatgcgtgca ttgcttcgtg
     4741 catctgttca tggtaattta cgtatcatgt tccctatggt agctacactc aaagaattcc
     4801 gcgcagcaaa agcgatcttt gaagaagaaa aacaaaaatt gataagtgaa ggcaaggaag
     4861 tatctgatac gatccaagtc ggcatcatga tcgagattcc agcagcagca gtcttagcag
     4921 acaagtttgc aaaagaagta gatttcttct ctgtaggtac gaacgatttg attcaataca
     4981 caatggcagc agaccgtatg aacgaacgcg tttcttactt gtaccaacca tataacccat
     5041 caattttacg tttgatcaaa aatgtaattg atgcagcaca cgctgaagga aaatgggcag
     5101 gtatgtgtgg agaaatggct ggagatcaaa cagctgttcc attgctagta ggtatgggtc
     5161 tagatgagtt ctcaatgagt gcgacatcta ttcttaaaac gcgtagttta atgaaacgct
     5221 tggacacagc gaaaatggct gaacttgctg atcgtgcatt gaaagaatgc gatatgatgg
     5281 aagaagtcgt tgaacttgtt catgaatatg taaaataaac aacgtatcaa aagctggtgt
     5341 ggcttgtaaa agagctacgc cagttttttt gttctttttt aagaaaacgt ttttgtcagt
     5401 aagaatagac aaaaataggg cttaagtttg agtgacagtt tgtaggctat gttatactat
     5461 ataagtgaag ggggacgtaa ggtgaaggta ttattatatt ttgaaagtga aaagatgctt
     5521 gcaaaatctg gaatcgggcg tgcgcttgat catcaaaaac gtgctctgac ggaagtcggt
     5581 atctcttata cactagatga aaaagaagat tatgacatcc tgcacatcaa tacatacgga
     5641 atcaatagtc ataatatggt caataaagcc agaagagaag gaaaaaaagt tgtctatcat
     5701 gcgcattcta cagaggaaga tttccgaaat tcctttatca gatcgaacca gctttctcct
     5761 atcgtaaaaa aatatctggt aggattgtac caaaaagcgg actatctgat cacgccaaca
     5821 ccttattcaa aacagttgtt ggaaagctat ggtatccgtg tgccgattca agctatttcc
     5881 aatgggatcg acttagagaa atatcaccct gatccaatga aagaacaaaa gttcagagaa
     5941 tatttcaaac tgtctccgga tcaaaaagta atcatttgtg tcggtttgtt tttcgaacgt
     6001 aaaggaatca ttgatttcgt agaaattgct aagaagatgc ccgaatacac atttatttgg
     6061 tttggtcatg ttcccatgta ctcgattcct cggaacatcc ggaaaattgt aaaagaagat
     6121 catcctgaaa atgtcctgtt tcctggttac attcgtggag agatcataga aggtgcgtat
     6181 tcaggtgcag atctattctt tttcccttct tatgaagaga cagaagggat cgttgtttta
     6241 gaagctttag caagcaaaca aaacgtactt gttcgagata ttccagtgta taatggctgg
     6301 ttagaagata gcaagaactg ctatatgggg aagacaaacg aagaatttat ccgactgatc
     6361 caacagatta ccaatcaaga actaccgagt acgacacaag ccggttatca aacagcaaaa
     6421 gagcgaagta tcaataaaat cggtgaagaa cttaaaaatg tatacgaaag tgtactgaat
     6481 gaaaaagtct ctagcaaatt aaaaaaagta aatcaggtca aggactagtt tggaggcgaa
     6541 aaacatgaaa atcggctttt ttaccgatac ctactttccg caagtcagcg gagttgctac
     6601 atcgatcaaa acattaaaac aagaattaga aagacatggg catgaagtct atatttttac
     6661 aacgaccgat cctaatgcgg ataagttgga aaaagatgtg attcgaatgc caagtgtacc
     6721 atttatttct ttcaaggatc gaagagttgt tgttagaggc atgtggtatg cttatttggt
     6781 tgccaaagaa ctagaactag atcttattca tacccataca gaattcggag cagggatact
     6841 tgggaagatg gtagctaaga agttgaaaat acctctgatc catacttacc atacgatgta
     6901 tgaagactac cttcattata tcggtaaagg aaaagtgatc aggcaatccc atgtaaaata
     6961 cttgtctaga ttatttgcaa atcatacgac aggtgtagtt tgtccaagtg aacgtgttat
     7021 tgatacatta cgcagctatg gtgtaatagc accgcttcgc gtgattccta ctggtatcga
     7081 cattgaaaaa ttcaaacgtt ctgatatcac tcagcaggat atcagcaaat taagggagtc
     7141 actaggtctt caggaaaacc atttgatgat tctttcttta agcaggattt cttatgagaa
     7201 aaatatccaa gccttgatta atgggtttcc tcaggtcatc tccgcttatc ctaacgccag
     7261 attagttatc gtaggaaaag gaccttatgt agaagagtta gaggaattga tctcagaact
     7321 gcagttagaa gaatttgtgc agttcacagg agaagtggac aacaatgatg tagcacttta
     7381 ttataaagcg gcagattatt ttgtcagtgc ttctacttca gaaacacaag ggcttactta
     7441 tacagaagcg atggcagccg gaacaccttg tgtcgtggaa ggaaatgctt atttgaaccg
     7501 attgttcgat catccttcat tagggaaaac ttttgaaacc gacgaagact ttgcaccagc
     7561 acttattgat tatatttcca gtgaagttcc taaagatcca aaagttttag aagctaaact
     7621 ttatgatatt tcatctacac atttcggcga agctatgatc gaattttatc aagacatggt
     7681 tgtttatcat gaagaagaga tgcgaagaaa agaagaagaa gactcgattg aacgaatcaa
     7741 aataaaatta aattcattta aaagataaaa ttcaaacatt ttttatgaaa aaatccttgt
     7801 ttctagcgta tactagcata gaagcaagga tttttgattt ttaggaggtc gaaaaaatga
     7861 aacttggttt tatcggaaca ggcgtcatgg gaagtgctgt cgcacgccat ctactagaag
     7921 caggacacga agtagctgtc tataatcgga caaaagcaaa agctgatcct ttagtaacag
     7981 aaggagctat ctgggcagat acaccaaaag cggtagcaga acaaagtaat attctcttta
     8041 caatggtagg ttaccccaaa gatgtagaag aaatctacta tggacagtcg gggatttttt
     8101 ctgcagatat ctcaggacat attttagttg atttgactac aagtacacca agcctggcag
     8161 aaaaaattgc aaaaacagca aaagaaaaag gcgcagatgc gttagatgca ccggtatccg
     8221 gtggtgactt aggagcaaag aatggtacac tgacgatcat ggtcggtgga gaagaagccg
     8281 tttatgatca agtactgcct ttattcaaag aatttggtac gacatttaca ttgcatggtt
     8341 ctgctgggaa aggtcagcat acaaaaatgg ctaatcagat catgattgca ggtacgatga
     8401 caggaatgac ggaaatgctt gtctatgcac aaaaaaacgg acttgattta aagaaagtga
     8461 ttgagacgct ttcaggtgga agtgcagcta actggtcttt aagcaattat tctcctcgta
     8521 ttttaaaaga agattacaca cctggttttt ttgtcaaaca ttttatcaaa gatttaaaga
     8581 ttgcattaga agaagcagaa aaaatggatc ttgtattgcc agcaactacc caagcattga
     8641 aactatatga agagttggca gataaaggtt ttgagaatga cggaacccaa gctttgatca
     8701 aactttggtg gcctgaagga aaaataccag aaaaaaaatc ataaaaaacg agttttttta
     8761 gagaaaatca atgcaagtag gctatgcttt tgatacaata taacagaaat aagaaaagga
     8821 ggacctccga tgacacattc acaattagtc gcaatcataa aacgactgga ggctatggtc
     8881 gagtcagcag ataatgaact gcaagttcgc cgttttgaaa aagaaggcgt agagaagtgt
     8941 acagtaactt atgataaagc gaccgataca tttgaattaa ctgaaacaga tactcatcag
     9001 caatacgaat ttgataatat cgatatcgta gcgatggaaa tctatgactt aatccaataa
     9061 attttaggat aattgacatt tgaagttgaa gatgcctaaa agaagccgag aagcaactaa
     9121 tttagttgct tttcagcttc ttttttgttt aacagttcaa tttcaaactg ttctttttct
     9181 aattttttgc ggtaactgat caagatttgt acaggatcga tttcttcttt tgacaattga
     9241 cgtttcaaag ataaatgagc ttctttcttt tcataataga agtcaggaga aacgtcacca
     9301 gaggtaatca ttgtttctgc aagttgacca taacaaacga ggtagtgctt tttctgactc
     9361 tcatctgctg ctaatggcat gctgaaggtg agcgatggtg ttcttaaaaa ctgcttttgt
     9421 tcctggatcc gtctaataaa ataagtaact aattcgatat ctttttgaag cataccggct
     9481 ttttcgaaat tcaactgata gatgaaatgt tgttgtcttt ttttcaagta agtcagtagc
     9541 tttttatttc ggccttgaaa cagcccttgg agttcctttt ttttctgttc aaaagtcatt
     9601 tcctgtaggt caggaagctg gactcgcaaa gctaacaaac taatttcaga caaccaaggc
     9661 atttgataag tttcttccat tatacgcaaa atagacggca tttttttata gagacgaaaa
     9721 ggcccgtatg ttcgagccgt aggagtatct gttaatacaa atcccttatt ggtaatatgt
     9781 acataattat aattactgaa ataattcatt tgtcggttat aaaaaggacg gtaatgttgg
     9841 atcaattgac actcgagcaa taaagcatct aattccgtgt ctactacgac gaaatcaaaa
     9901 tctgttatat gatgaatcat acgtaatact ttttttgaat gctgtttatt ctgatgaaaa
     9961 tagctgctta ctctattttt gagccgtttt gctttaccaa catagatgac cttaccatct
    10021 cggtctttca taagatagac acccggcagc atggggagag ttttcatttt ttcttttaac
    10081 ataggatctc cttttacgct ttgaataaaa agactataac aaattttgaa ataatggaca
    10141 agttttaggg aattctatag ttctgttcac agaaaatact ttgataatca aaatatgtga
    10201 gatagatgat ttttctaata aaagaaatta taaatgctga tttatcagtt gttttaaatg
    10261 agtaaaatct taaaaaaagc tcatatagta aaaaaatgat cttttaaggt tgcattttga
    10321 aaaaagttaa gatatagttt gaacatcaaa agatttgata atcaaactaa ttagtggacg
    10381 gtggaacatg gaaccagatt taaaaacagt aaatgattat cttgttagtg tcttcaatga
    10441 tattttgaca atcgaagagt ctgagctgaa aaaatctcaa ttcaaagatc tgtcaatcac
    10501 agagatgcac acgatcgagg caatcgggat gtacaagaaa aaaacaactt cagaagtagc
    10561 caaagaacta tcaattactg ttgggacctt gaccactgct attaacaagt tagtaaaaaa
    10621 aggctatgtc gaacgtatcc gcagtgaaga tgaccgccgc gttgtaaagt tgggactaac
    10681 gaaaaaagga aagttactat ttcgggtcca tcagcatttt catcgtgaaa tggtcaagaa
    10741 catcttagac ggaatggcta cggaggaaca gcatgccttg ctggatgcac tgaaaaactt
    10801 gcacgacttc ttgcaagact ataagtgagg atatttaatg gaacaatttg gaatgattac
    10861 tgcaacagcc agcgtccttc ctgaaaagat tattactaat aatgatcttt ccaagatgat
    10921 ggatacctct gatgaatgga tttcgtcaag gacgggtatt cgtgaacgaa gatgtgtaac
    10981 aaatcaggag acttctgatt tatgcatttt agtggcggaa aaattgataa aacagaaaaa
    11041 tctaaaccct aaagatttgg attttatttt agtagcaaca atgtcgcccg attacacgac
    11101 accatctgta gcagcacaag tacaagggaa attgggagca actcatgcta tcgcttttga
    11161 tatcagtgct gcgtgctcag gatttgttta tgcgttaagc atggctgaaa aaatgatccg
    11221 ctgcggctca actaagggac tggtgattgg tggtgaaaca ctatctaagc taatcgattg
    11281 gtctgatcgt acgactgctg tgttgtttgg cgatggagca ggtgggattc tcttagaagc
    11341 gaatccacag aaaaaattgc tgaaagaaaa attagcagct gacggtacca gaagtagctc
    11401 attgaccgct ggctaccagc aaaataaaaa tccgttctat tcagaagatt cagaaggttc
    11461 gtattatttg caaatgactg gcagagatat ttttgatttt gccgtacgag acgttgcaaa
    11521 caatatccaa gaagtcatga aagacaaacc agttgattat ctgcttttgc atcaggcaaa
    11581 cctcagaatt attgagaaaa ttgcccgaaa agtaaagatg ccgcaagaaa agttcctgac
    11641 caatatggat aaatatggga atacatctgc tgcaagcatc cctatcttat tggatgaagc
    11701 agtttctagt ggaaagatca ccttaggaaa acagcagaaa gtaatattta caggctatgg
    11761 cggaggttta acatggggaa gtattctcat ggagttgtag actgttaaat tataaaaata
    11821 aaaagcaaac aatatcggag gaatatatta ttatggtatt cgaaaaaatt caagaaatca
    11881 tcgcagaaga attaggaaaa gaaactgaag aaatcaaatt gactactgac atccaagaag
    11941 acttagaagc tgacagcttg gatttattcc aaatcatcaa tgaaattgaa gatgaatttg
    12001 acgtgaaaat cgaaacagaa gacggaatca aaacggttca agatttagtg acttacgtag
    12061 aaaaacaaac tgcataatca ttaaaattag gttgggggct gggacatttc ctgaaatagg
    12121 aatgtctcgg cctttttgaa taggaagaat caaacatata ttctggatat attggagaaa
    12181 aacatgaaaa cagcattctt atttagtggc caaggtgcac aatatcaagg tatgggaaaa
    12241 gatttatatg aagaagccgt tgtaaagcag acatttgatg aagcaagtga gattctcggc
    12301 tacgatatgg ctgaactttg ctttacagaa aatgaacgtt tggatcagac gcaatataca
    12361 cagccagcta ttctaacagt cagcatcgcg tattatcgct tattgaagga gcatggaatc
    12421 atcccagatg cagctttagg actgagttta ggagaatatt cggcattagt agctagtaat
    12481 gcgctatcct tcactgaagc agttgcgtta gtagcaaaaa ga
//
LOCUS       DADGKS010000077        12229 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.078, whole genome shotgun sequence.
ACCESSION   DADGKS010000077 DADGKS010000000
VERSION     DADGKS010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12229
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.078"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            42..2180
                     /locus_tag="JXV47_002357"
     CDS             42..2180
                     /locus_tag="JXV47_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAX1488371.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(2548..3531)
                     /locus_tag="JXV47_002358"
     CDS             complement(2548..3531)
                     /locus_tag="JXV47_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HAX1488372.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            3909..5300
                     /locus_tag="JXV47_002359"
     CDS             3909..5300
                     /locus_tag="JXV47_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAX1488373.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            5316..6356
                     /locus_tag="JXV47_002360"
     CDS             5316..6356
                     /locus_tag="JXV47_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAX1488374.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            6375..7460
                     /locus_tag="JXV47_002361"
     CDS             6375..7460
                     /locus_tag="JXV47_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HAX1488375.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            7493..8455
                     /locus_tag="JXV47_002362"
     CDS             7493..8455
                     /locus_tag="JXV47_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HAX1488376.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTAFKIFR
                     AIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGM
                     FAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKW
                     FDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
     gene            8448..9875
                     /locus_tag="JXV47_002363"
     CDS             8448..9875
                     /locus_tag="JXV47_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HAX1488377.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKEN"
     gene            9877..10947
                     /locus_tag="JXV47_002364"
     CDS             9877..10947
                     /locus_tag="JXV47_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488378.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            10934..>12229
                     /locus_tag="JXV47_002365"
     CDS             10934..>12229
                     /locus_tag="JXV47_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HAX1488379.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFS"
BASE COUNT         4223 a         1749 c         2163 g         4094 t
ORIGIN      
        1 taaataatga ttaacttata aagataagga gtaaacgaat cgtgcaaaaa aaagaaattg
       61 ccgtatttat cgatcaaatc actcgtgaac gggccactgg cgatttgctt attgtgggct
      121 gggcaattga tgaagtgacc aaagaaatcc ctacgataaa ggtagaaaaa gaaaatgtga
      181 ttgctgaagc aacacatgtc gtaagattgg atatcaatca tttatataat cttgatgtta
      241 agacccaaag cggttttaag gtacgtttat cagggaaaat gagaggaaaa gccatcttag
      301 acttccaaac agcgagacat caaaatggca tagctgtgaa attaaacggt aaataccctt
      361 atgatgacgg cattgaatct tcatgggaaa gaaaaaaaag attactgaaa aaagggataa
      421 attatgcaag gactcatggc gtaaaaaaag cgatccgtcg ggtcaaattg gaattgaagc
      481 caggatcgat cgactatgca gagtggatca gtcgtcatga gaaaccagat ttgaaagagc
      541 aaaggaaaga agcacaagga tttgcgtacc gtccattgat ttccatactt atgcctgtct
      601 ataacgttga aatcaaatgg ctcgaaaaat gcattgattc ggtactggat caaacgtatg
      661 atcattggga actatgtatc agtgatgatg cttctactga tccagctatc cgaaagtgtc
      721 tggaatccta tcaagcaaaa gatgatagaa tcaaagtcgt tttccgaaaa gaaaatggac
      781 acatcagtct ggcaactaat tctgcattgg aaatagcaga aggagaattt atagcactct
      841 tagataatga tgatgaatta ccgccatttg cattatatga agtggcaaaa gtgctaaacg
      901 tacatccaga actggatgtg atctacagtg acgaagataa aatcgatgca gatggcaatc
      961 gctttgatcc gcatttcaaa gcagactggt cgcctgatac attgatggga aataattata
     1021 tctctcactt aggcgtatat cgaacaagca ttgttaaaga acttggcggt ttccgtaaag
     1081 gctatgaagg ttctcaagat tatgatttgg tccttcgtgt gacagaacaa atccctgcag
     1141 atcatattta ccacattgac cgagtcttgt atcattggcg gacgatccca ggatcaactg
     1201 caagtaatgg cgaagccaaa agttatatct atgattccgg agtgaaagca ttgacagatg
     1261 ccctgtctag aagaaacatc aaaggaagcg tacgtcctgg cagaatttct ggattttatg
     1321 agattgctta tgacgtcttg caagaggatt tggtcagtgt gatcattcca acgaagaatg
     1381 gctatgaaga tctaaaaact tgtgtggatt cgatcatcga aaaaacgtct tattcaaatt
     1441 atgaaatcat tattgcggat aacggaagta cagatccaaa aatgcaagaa ttatttgcag
     1501 aatacaagca tcagctgaaa gaccgcttta tcgtagaatt gattgacatt ccattcaatt
     1561 attctcgaat taacaattta gcagcagaaa aagcaaacgg caaatacttt ttattcttga
     1621 ataacgatac agaagtgatt gagccagatt ggatgacggt gatggtttct tatgcacagt
     1681 ttgatcgaat cggctgtgta ggagcaaaac tgttttatcc agatgataca acgcagcatg
     1741 caggagtatt attaggaatc ggtggtgttg cagggcatgc attgaataac tatgatcgaa
     1801 cacattgtgg ttatttcggc cgattggtca ttgacgtcaa ttacttagca gtcactgcag
     1861 cttgtatgat ggtcaaggca gctgacttca atgctgttaa cgggtttgat gaaacattag
     1921 aagtagcatt caacgatgtt gacttgtgct tgaaagttta tgaactgggt cgttacaatg
     1981 tctatgcaca tcaagcagaa ttgtaccatt tcgaatctaa atcaagaggt tatgaagata
     2041 ctccagaaaa acaaagacgt tttgctggtg aaatcaaaaa aatgcaagat aaatggccag
     2101 catatattgc gcatgatcca ttttacaatg ataatttaac aaaagaagga atcggcgact
     2161 tttcgttgag accagattaa actataataa aaagctgtta tgttgtgatt cgctcgcaca
     2221 taacggcttt ttatagtttt ttgtcaaaaa aaggcagaag gtgccgactc aaaaaaataa
     2281 gtcgaggttg ggacagaagt gtttaactcc gagaaataag aagaaattca cgaaaattgc
     2341 ttttcaaatt tttgtgaatt tcggcttatt taagaagaag ttgcttctgc tcccaccgtt
     2401 tattcgtttt taaagaatga gacaaaagtg tttcttactt ttgtcccacg ctcttattca
     2461 tgctcagagc gccaatagat acaaaatcat agccaaagtt tcacgaaccc tagctgtcaa
     2521 agaatcgata ttttatttta atataggcta ttttaaaata aatggtttaa ggtattcctc
     2581 tacaaaagcc actctatcaa ttatcatggg tttaaaataa gaagtgatgg agataaccag
     2641 attgttctta gcgtcaatat aaagaacatt tccactatta ccaattgctg aatatatttc
     2701 gttctcagaa tctaataccc accataaata gccatatctc atattttgta agtcttctaa
     2761 agcactggtt ctaggtttga acatctcgtt tatccacatg ggtggtacga tttgttttcc
     2821 tttatacatc cctttattta ggcataatac accaattttt gccagatcac ttgccgataa
     2881 acacaaacca tatcctgccg tcccgatatt tagtggatca caaaaccaga cattggtttt
     2941 aggagactta tccattgtaa actgcttatg ttcttcagct gtttcagcat aataattgac
     3001 atggtttggt atccctatag gatcaaatag atacttattg gcaaaatcaa cagttgttag
     3061 cttacttgtc tgatacaaca agccagttaa tatgtgtaaa cagacagttt gatagttgaa
     3121 ttcgccggtt ataccttttc ttcctcccaa taaatctagt gatgtttttg tccaatcttc
     3181 acttgaacag acttttgtcc atggatcgcc tttacatttg tagggtgctt tcattgttag
     3241 caagtgcttg attgtaatag cgtaaatagt tttctccccg cgtttcactt tatactctgg
     3301 aaaataatct aatactttat catcgatact tttgattaat ccttgctcta aagcaatgcc
     3361 aatcagcaaa gatacaatac ttttcgttgc tgacatgata tgacaagtat cgtctttttt
     3421 ataaccattc cattcatctg tataaacttc taccccatcc ttatatgcga caatttgaca
     3481 tatatttggt tgtcgaaaac caataaaatc atgcaactct tgtttattca taagatatta
     3541 cctcactttc ttctataagc ataatgtcat taaaaatcga tttcaatttt ttcgattctt
     3601 cacgtaatac aggtattctt atggactaga cagcgctttg ggaagatgga ttctctgaaa
     3661 aatataaagg ttcactttat gagtggataa aaaaagcagc aaatacttcg acttctttaa
     3721 tttaccaaca ttagtgaaaa tcgattcatc tggagatttg taatttagag tccttgtctt
     3781 gattagaggt gtataaagct ttttattaga catttttaaa ttccattaca atttgcttat
     3841 aaactaggtt tttaaaggtg actatggtaa gataatagag atattatttt gtgattagga
     3901 gtgtatatat gaataaaaat ggagaatgga gtgctgcacg acggatattc attatattaa
     3961 tggatgttat tgtatacaat gcagcaatat atagtagttt cttactgaag tttcgtggag
     4021 agatcccatt acgaaattta gaaactttcc aacactcagc aattattatt tcagtgattt
     4081 ttattgcgtt gaacattttg ttgggtgcat atgtttttta taatcgaatg atcagtgaca
     4141 tcgtgtttgt cacagtcatc ggtcaggtat tgatgacact agggatcatg gtagtgactt
     4201 ttgcgggccg ctggtttgct tttccacgtc ttgttatctt actttcattt gttctcggta
     4261 cgcttttctt aagtatctat cgtattctcg tatataaact ttatttacgc gtaagtcgag
     4321 ataaaaaggt cgtcattatt gggttagaaa aggatgtcgc accagcaatc caaaattttg
     4381 gttcaaagaa aaacaacaaa cataaagtcg aagcagtcat tcttgataac tattatgcaa
     4441 acatcaaaaa tatgattaaa gacatcgata ttgtctatct tgcttctcat atcgaagaaa
     4501 ctgaaaaaat caaaatctat caattagtta ctaaaaatga aaaaaaattg tttttgaata
     4561 caacatttga aaacttgaca ttgatcaatc caaatattat gaatttcgaa gatgaaagta
     4621 ttattgaagc atctggattt agaatccaac ctgaatatga actattcaaa cgtttgtttg
     4681 atatcatcgt ttcacttgtt ttattagtta ttgcttcacc atttatgtta ttcacagcaa
     4741 ttttagtcaa agtgacatca ccgggaccaa tcatctataa acaagtgcgg atcacaaaaa
     4801 atcaaaagga attttcaatc tataaattcc gctcgatgac cgccacagcc gaagcaaaat
     4861 ctggaccagt tttagctaag agcaatgatg cacgagtaac gcctgtaggt aaatttattc
     4921 gagctgtccg ctttgatgaa ttaccacaaa tcttcaatgt gctgaaaggc gatatgtcga
     4981 tcgtaggacc acgtcctgaa cgtcctttct tcgtcgatca gttcaatgca gaaaaccctt
     5041 attactactt acggcataat gttcgtgctg gtatcactgg gtatgcacaa gtctatggaa
     5101 aatatgtctc tgattacaac agtaaattac gttttgattt actttatatc aaaaaatatt
     5161 cattgatgct tgatttaaag atcttgctgc aaaccatcaa gatcctattt gataaaatgt
     5221 cctctcaagg acttgaagaa gacgaaaatg tgatctcatt ggcagaaatt gcttttccga
     5281 atgaaaaaat ctttcgctag ttgggaggcg taaaaatgaa caatccgaaa ttcagcataa
     5341 tcgtaccagt atacaatgca gaagcaacta ttggtcgaac gattgatatt ctaaaagaat
     5401 tggattatga agagtacgaa gtcgttttag taaatgatgg atcaacagat caaacacagg
     5461 aaatcattca agaactgatt gaaaatgatg aacgttttga attgattact acgaccaatc
     5521 aagggcccgg attagcaaga aacgaaggaa taagacagtc aaaaggagaa tatctcttat
     5581 tcttcgatgc agatgacacg ccagtaaaaa cgatcttgtc agattatgat catttgctag
     5641 aaaagagtcc aaaagcggat cttgttgtta gttcgtttgt ttttcgtaca atggacgagg
     5701 gaagaatcgt ttccgaaaaa gaaaacttag ttacagaatg tcactatcta actcacgaag
     5761 agtttataaa agacatgtat cagttaatga atgaacagtt gatgtatgtt gtatggaaca
     5821 aatgctatcg tagcgatatt ctgaaaaata accaaattct atttaaaact tataatagtt
     5881 gtgaggatcg aatatttaac ttacattatt atgaatactg tcatcaagtg atcatgaacc
     5941 caaaagtaga atatatttat gaatttgaag gtgggaaggg gatcactaat caataccgac
     6001 ctaacaagtt cgaaacattt aaagaattct attcattagc aaatactgta acagacgata
     6061 ttaataaaga cggtatggcg gcgcttcttt taaaagggac aacttcagtt attttttcta
     6121 tttatagtac ctctgcaaga acttcaaaag agaagaaaga cgaagcaaag cagatattga
     6181 gtgatccagt gatccgagaa gccaagcaaa ttgctaagac ggattcttca gcaaaaaaaa
     6241 taacaaagtt gctttacaat atgccagctc cactattttt atctgctgta aaagttggaa
     6301 gcttcgttga agtgaaaatg ccagggttaa tggctgcttt gaagcgagta tattagttaa
     6361 tggaggaaaa tataatgaaa agaattttgc attttcaggg acgaatgggt ttaggtggag
     6421 cagagtcttt catgatgaat ttatatcgta aaattgatcg tacaaactat caatttgatt
     6481 ttttgattta tgaagattat gcagatgttc aagactatca ttcagagatt gaaagattag
     6541 gaggccgtat ttttgttgta cctaatccta agaaaaatat ttttaaatat ttaatagaag
     6601 tgaataagtt actaaaaaaa gaatcttttt ctatagttca caatcaggtt tattttggcg
     6661 ggggaattaa tttatggtta gccaaaaaga atggaatcag acagagaatt gctcatagcc
     6721 atgcaactga agatggaaaa tctcaaaata ttgtaatgaa tgtattgcgt aaatttttaa
     6781 ccaaattgtt gttacaaaat gcaacagact accttgccgt tagtcaagaa gctggtgaaa
     6841 gtctgtttca aaaccacccc tttgagatag ttcataatgg tattgattta gagctttata
     6901 gtaaaaattc agaagctaag gttaataaga gaaaagaatt ggatatctca atgagtactt
     6961 ttgttgtggg aaacattgga cgattagaga aacaaaaaaa tcaatcttat ttgttagaga
     7021 tttttttaga aatactaaaa atgaattctg attcttactt gattttagta ggtgaagggt
     7081 cacttagaaa taaactgaaa gccaaagcag tagaattgga tatagagaaa agagtaaaat
     7141 ttttaggaga aagaaacgat attcccgagt tattatctgt gatggatgtt tttgtaatgc
     7201 cttctcttta tgaaggtctg ccaatggttg gattagaagc acaagcagca aaattaaaat
     7261 tagtcttagc agatactatt tccaaagata caaagttaac aaataatgtg gattttgtat
     7321 cattagatga aacaccacaa gaatgggcaa aaaaagtaat aaaagagccg tatgctaata
     7381 aaataacaca agaactaaag agttatgatg tttcgtacac tactgaacaa atggagagta
     7441 tatatagtag agatcattaa aaatgttcaa gatattttag gagtgattat ttttgaaaat
     7501 atgttatttg atattggcat acaatgatat tggcaactta aagagattgg tcaatcgatt
     7561 gaacgaaaat gcagttttta ttattcatat agataaaaaa actgatatag aaccatttat
     7621 tgaagcattt aaatcatatg ataatgttga atttttatgt aataaaaacc gtgttaaaat
     7681 ttattggggt ggtttttcca ttgtacaagc agaaatcaat ttagtaaaga gagcattaca
     7741 aaatgagaaa tatttaaaat atgtattatt atctggtgct gattatccaa tcaaagataa
     7801 tgagtatatt tataattatt ttaaaaagaa tagttcagtg gagtttattc gtggaataga
     7861 tctagatcaa attaaacata aagaatttta ttataaacat atagatgtat atcaaaaaca
     7921 tgattatcct agaattaata ggaataacac aactgcattt aaaattttta gagctataat
     7981 taatcgttgt ctgaggatga ttaaacttcc cccaaaaatt agacaccata aatttgattt
     8041 gtatcatggt tctcaatggt gggctttgtc gaaagaatgc ctaacagaat taatacaaat
     8101 gtatgaacaa aatcaacaag actacctgaa ttttaaaata ggtatgtttg ccccagatga
     8161 aaaatttttt catacacttt tttttaattc ctcgttcaaa aataaaaatg ttattggagg
     8221 accagattta ccacttgaat tgaaaaatat tgaagaaact actttacaaa cttcgaaatt
     8281 agcaaatatt catattattg atccttccat gaacaaatgg tttgatgaaa gggatataga
     8341 tcaaataaaa gaaagtgaaa aattatttgt aagaaaagtt aaatcggatt actctgataa
     8401 actattaaat agaattgata aagaaatttt gaaagttgga aatatagatg aatagaatag
     8461 tacctgtttt agagaagagt ttattaagtc gagatgcgtt tcgagtaata aatttaatca
     8521 tttgtctgct ttattttatg cctagtactt ttaatgtaac taatatcccg atgaaaatag
     8581 cttttgcttg gggtggaatt atagttttgt atgaggtttt tataaagaaa aattttttta
     8641 aaatgcgttt ttcttggcta ctgattggag caatgattag ttttatctta actataatca
     8701 ttaacagaga aaatttttta attccatcta tttataattt tggatatttg ctgattactt
     8761 tgatagtaat ttttcctgca gacttttcac aaagtgaaga ggaaaaaaag aaaaaaatgg
     8821 tgtattttaa taatgttttc attatcataa tttttttagc tgcgctaata tctatctatc
     8881 aatttatttt tttgatttct tatcatgtcc caacaggaac gccaggatta cttgcaagac
     8941 aaggttttat tgaacatcgg ttatttggtg tctatacaag tccaaatgtt ggagctatgt
     9001 ttggatatac ttctattatt ttaagtttaa ttagtgtatt aatttcaaaa ataacaaaaa
     9061 cgattcgtgt tttttatatg atgaatttta tcgtacaaat attttatatt acactttctt
     9121 cgtctagagg tgcccaggta gtaatttgtt cttttttagt attatttctt ttgttgtttg
     9181 ccaattcaaa atttagaaag agcattagag aagtactacc tgtaaaaatc aaatggatgg
     9241 taagcatatt attagttcta ttggtatatt tttcttttgg tactaattat gctaaggatt
     9301 ttttagcaac aattcctgta tcgattgata gaaaagtaga agttatagag tcaaatgaat
     9361 cagataaaac tccacttcca gaaaaagaag taatattaca gcattctagt gataactccg
     9421 aaatttcagc tggtcgtttt acgatttgga aagctgcgct taaagttata agaccaactt
     9481 tgttatttgg ttatggagag accgatttct atgggaatag cgatgcaaaa tttttgaaaa
     9541 aagtagatct tgatactaca gatgtgaatg aactaaaaag agcacatgga aacatgcata
     9601 atggatttct tcaagtactt gtatcaagtg gtataattgc ttttatatgt atctatgctt
     9661 tctatgtgtt aaatatcttt agtttactca aaacattttt tagaagtaaa gtgaattatg
     9721 cgtttcttgg tattgtttta atttttatac tatctatttt tatagatgaa atggtggagg
     9781 ctcatgtact tttcaataag cgcgatgtca tttcaattgt tttctggtat tatttgggaa
     9841 gcatttctta cttgtattta aaaaaggaga attaatatga agacagcttt cattgcttgg
     9901 actcctttac atttgattaa tatattaaat gtttatcaaa atttttaccg agaatcaaaa
     9961 ggagatttat ttatttattc tgaatttgaa aacgctagaa gatatagtga gcgtataaaa
    10021 gaattagggc tatttaatga tgttgttttt gtgaatcacc ggaaaatcgg ttcttccttt
    10081 aaacgtaaaa ttaacttgtt aactaaccat aatcaatttt tctcggatga tttatccgtt
    10141 tatgatgaaa tttttataca gggggaaaat tatttcacaa aaatactttt ctccaatgtt
    10201 tacaaaaaaa atccagatgt aaaactaaat tatatagaag atggtttggg tacttatttg
    10261 aagaagagta tattttcaac aagtaaaaac gttcaaagag tttttaaaat attaaataaa
    10321 aatagcatct tcaaaaaaaa aattgacgat tattttgtct attgtccgga attgttactt
    10381 tatgatgtaa aaaatataaa aaaaattccc aaaatagatg aaaacagtaa attgatgaaa
    10441 aacatacaat caatctttgg gatagaagaa gtttttgtcg gagataaatg tatctttttt
    10501 gatcaacctt tattatctga tggttatggc atagatgaaa cagatatttt cgctaaagta
    10561 aatagtatat tttctggaaa aaaagaaact ttaattaagc ttcatcctag agcaaggaca
    10621 aatcgttatg gtgaaaaaaa catattgaat tccagtttac cgtttgaagt cttgctactt
    10681 gaaaatgact tctcttcaac acttttgatt agtcctatat ctacaatttc tttttcacca
    10741 tctatgatgt ttgaaaagac gatcaactct attatgttgg ctaaattaat tttaaatgaa
    10801 tatacagcat tatctgaaga taaaaaagaa acattgacaa atattgttct tttctgtgaa
    10861 cattataacc gtctatcaga agaaaaaatt ttactcccag aaaactgggc agaattaaga
    10921 aagttggtag agtatgggat tatttaacac actttccaag tcaaaattag ttaagtccag
    10981 tttctggtat actataggga atttttttat taagggaatt tcattcataa ctattcctat
    11041 ttttgtaaat attactactc aagcagaata tggtttgatt aataatttca cttcatttgt
    11101 atcaattttt tcgattcttg ttgggctaag cctaaattcg gcaattaata atgcaagttt
    11161 tgactataaa gatgacataa atgaatttat gtcatcggta ctttctctag ctacactttc
    11221 gttaattgtg ttcttattaa tagggaacat atattttttg ttttcaaatg ctttttttga
    11281 tatgaaccaa cttgtattta atttgatgtt attacaaagt tttgctagtt ttgtaattag
    11341 ttatatccag tcttatttta cgattaactt taaccatttt aaatatttga ttttatcttt
    11401 tatatctact tttttgaata ttgcaatctc tgtagctttg atgcagacat tatattttga
    11461 tgataaatat gttggcagag tagtcggcgg aacactgtca tttgtgttga taggtttagt
    11521 aatttattta agaataatga taaagggtgc tcattttttt gataaaaaac agtggagata
    11581 cgctttaaaa atctctttgc cgctaatccc acattcctta gcaaatatag ttttagcaca
    11641 attcgataga attatgatta attcttattt aggtcctgct gcggggggaa tatattccta
    11701 cattagtaac ataggtatta ttctaagcgt aatatggatg tctactaata acgcctgggt
    11761 tccatggttc tatggtgaga tgagtaaaaa taatgaaaaa aaagtgaaga aagttagtaa
    11821 ctattattta gtagtcttta ctttgattac gatgattgta atggtagttt cgattgattt
    11881 agcaaaattt atggctccga aagactatta ttctgggtta tctttagtgg ttccgataac
    11941 cttaggctat ttctttcagt ttttatatag tttaccagtt aatgctgaat tttatgagaa
    12001 aaaaacatcg tttattgcga ttggtacagt agcaagtgct atagttaata tactattaaa
    12061 catgattttc atacctaggt taggaataat tgctgctgga tacacaaccg tatttacgta
    12121 ttttttactt tttatttttc attataatat cgctaaaaaa attacgaata aacaattatt
    12181 tgacacaaaa aaaatatgta tcataataat ttttgtatca attttttct
//
LOCUS       DADGKS010000078        12144 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.079, whole genome shotgun sequence.
ACCESSION   DADGKS010000078 DADGKS010000000
VERSION     DADGKS010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12144
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.079"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..566
                     /locus_tag="JXV47_002366"
     CDS             <1..566
                     /locus_tag="JXV47_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAX1488380.1"
                     /translation="YFKSEKDTSSLTLTLEEGVEPDKVTSKVINQLKEKGSLKHLGEY
                     EVLDTAMLTKGIGQILSTITYFITAVAGISLFIAGVGVMNMMYISVSERTKEIGIRRA
                     LGATRKSIMLQFLLEGLILTLSGGLIGYLLGMALAYSVGSLIKVNVSLDLFTILLAVG
                     VSSVIGLVFSVMPASEAAKKDLIDILR"
     gene            967..1572
                     /locus_tag="JXV47_002367"
     CDS             967..1572
                     /locus_tag="JXV47_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HAX1488381.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            1588..2160
                     /locus_tag="JXV47_002368"
     CDS             1588..2160
                     /locus_tag="JXV47_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAX1488382.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2412..2669)
                     /locus_tag="JXV47_002369"
     CDS             complement(2412..2669)
                     /locus_tag="JXV47_002369"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488383.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIF
                     MIVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
     gene            complement(2795..3610)
                     /locus_tag="JXV47_002370"
     CDS             complement(2795..3610)
                     /locus_tag="JXV47_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488384.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
     gene            4127..5452
                     /locus_tag="JXV47_002371"
     CDS             4127..5452
                     /locus_tag="JXV47_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAX1488385.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRL
                     NQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            5445..5795
                     /locus_tag="JXV47_002372"
     CDS             5445..5795
                     /locus_tag="JXV47_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488386.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
     gene            5777..5962
                     /locus_tag="JXV47_002373"
     CDS             5777..5962
                     /locus_tag="JXV47_002373"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488387.1"
                     /translation="MGSIRMNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSF
                     YVEAAAGYHKYEYYIGY"
     gene            complement(6866..7141)
                     /locus_tag="JXV47_002374"
     CDS             complement(6866..7141)
                     /locus_tag="JXV47_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HAX1488388.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(7113..8066)
                     /locus_tag="JXV47_002375"
     CDS             complement(7113..8066)
                     /locus_tag="JXV47_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAX1488389.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            8678..10171
                     /locus_tag="JXV47_002376"
     CDS             8678..10171
                     /locus_tag="JXV47_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepR"
                     /protein_id="HAX1488390.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            10306..10602
                     /locus_tag="JXV47_002377"
     CDS             10306..10602
                     /locus_tag="JXV47_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HAX1488391.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            10703..11554
                     /locus_tag="JXV47_002378"
     CDS             10703..11554
                     /locus_tag="JXV47_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488392.1"
                     /translation="MKSDDWIEHNWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            11575..11787
                     /locus_tag="JXV47_002379"
     CDS             11575..11787
                     /locus_tag="JXV47_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488393.1"
                     /translation="MIPLYRIVLIVGMELKTLKKEQLFKVKERHNQLLCSKTGTMNIE
                     YRTEYLELTNQTDFLLIRKQQEQEKN"
BASE COUNT         4172 a         1863 c         2268 g         3841 t
ORIGIN      
        1 attattttaa gtctgaaaag gatacatcgt ctctaacgtt aactttagag gaaggagttg
       61 aacctgacaa ggtgacctct aaagtgataa accaattgaa agaaaaaggt agtttgaaac
      121 atttggggga atatgaagtg ttagatacgg ctatgttaac gaaaggaatt ggtcaaatcc
      181 tcagtacgat cacttatttt ataacagctg tagcaggtat atctttattt atcgcagggg
      241 taggtgtaat gaacatgatg tatatatctg tatctgaacg aacaaaagag atcggtataa
      301 gaagagccct aggagctact cgaaaatcga ttatgctgca gttcctttta gaaggtttga
      361 ttttaactct ttcaggaggg ttaattggct atttattagg aatggctctt gcttatagtg
      421 ttggttcttt gataaaggta aacgtgtcac ttgatctatt tactatttta ctagcggttg
      481 gggtatcttc ggttattgga ctggtctttt ctgtaatgcc cgcttcagag gctgcaaaaa
      541 aagatttaat tgatattctt agataaaatc agaatgacaa gaatatttac gttctagatt
      601 ctaaaataaa acacaaagag accaaccagg caccctattg tttctttgta gtatagagat
      661 attctttggc ttgtaagaga tcaatagagt taggtgaccg gagttcgaaa taaaggaaat
      721 ttttgattgt ataggagaat tctttatccc taatatttag aattttgagt atgccatgtt
      781 gatgttttag attctctata aatatagagg tgtatcaaag gtcaactaga ctgtgcaaaa
      841 tagagacact tgaaaaatct atcgggggtc agaaacttaa tagtttttga cacataaaca
      901 aaatcgcgat ataatggggt tgagagtgtt tcataaactt atgtcataaa gttaaggaga
      961 tttcgcatga ttttagagaa taaattggga ttaaccaatc aagttgagtt ggctaaggtt
     1021 gaagaaaaac tcagtaaaca aaaagcgaaa gaattgtacg attgtggaaa aataaatgaa
     1081 atcgaagttg gtacatttaa aggtttatct gaaattcatg aatttctatt ttcggatatt
     1141 tacgattttg ccggaaaaat ccgatcggtc aatattgcaa aaggaaattt tcgatttgca
     1201 ccagttatgt atttagaaca ttcgttacag catattgatc agatgccaca aacttctttt
     1261 gaagagatta tcaagaaata tgtggagatg aatatcgctc acccatttcg agaaggaaat
     1321 ggccgaagta ctagaatttg gctggatctc attttaaagg aagaattgca aaaagttgta
     1381 gattggaact taatcgataa agcagactat ctttctgcaa tggagcgaag tcccataaac
     1441 gatttggaaa tacgctatct aatttccaat gctctgactg ataaaattga cgatcgcgag
     1501 ttatatatga aaggaatcga tgtcagctat ttctatgaag ggtattctga gtatacgata
     1561 gatgatttgt aaaagtaggt ggaccaaatg acgaaatatg gatatgcacg tgtctcaacc
     1621 gcttctcaaa gtacaaaaga acaaattcaa cagttgcttg agaacggcgt agagaagaag
     1681 aatatttttt cagaaaaatt tacgggtaca aaacgggatc ggccaaaatt caatcagctg
     1741 ttggctggtc tgaagcctgg agatgaaata gttgttacga agcttgatcg atttgctcgt
     1801 aacacgagag aagcattaga gatcattgaa cctttactcg atgataacgt aacgatcaag
     1861 gttttgaatc taggaacgat tgaaaatacg tccatggggc gaatggtgac acggacgttg
     1921 ttgagtgtag cagaaatgga acgtgatatg attgtggaac gtacccaaga aggaaaaatg
     1981 tttgcaagaa agaataatcc taatttcaga gaaggacgtc cgaaagcaac aatcacaccg
     2041 aagaagaggc acgcatatga actgcttact tcaggtaaat cgtataagga agttgaagct
     2101 ataaccggtt tcagtcgcag tacgcttttt agaataaaga agaaaattga agaaagttaa
     2161 aaaagaagtc tcagcgaacc agacaggtaa atacttaatg cgttctagat atgagtctat
     2221 tagcatgttg tgaaatataa tattttttta tttacttgat ttctgctcaa aaaatgtgta
     2281 tggtaactgt aaaaggtaaa gtaattaaag gtatgctagc cacgcttact atattaggat
     2341 accatcatat atttataatg aacgatttgt tcgtctacca aacaacacat atcgttcagc
     2401 gtaagtcacg tttaggaacg tggctttttt agtgttatta tcgataaata atctattgac
     2461 tctattgatt ttatctccat atccctacgg tgttgattgt ctttagatct ttcatttaag
     2521 aaccaaataa ctatcataaa aatcagcact gctgctaata taataaacag cattcctatt
     2581 gtgatattac ctattgattt taccataact acgattaaag taataatggc attcaagtct
     2641 cctttgttct ctatatataa attagccata aatcatcttc ctttcaaatt aagatacttg
     2701 tttgatacca ataaatagta agcgtggcta gcataccttt ttctgtaata gcaagtgttc
     2761 taatagtcca aacttaatga tggaccgatg ctagttatag tacagtaatg ttttctttct
     2821 tatctagatt tttagtaagc tctatcagca aatctaacaa atctgagtcc ttttcagaaa
     2881 ctaaattaaa tctagtgttt acaacaaagt tttcatgttc tatattgttt agattatttg
     2941 cggaaaggag ggcttctaga tcttgacatt caaatctata tgcatcgtca taaatcttac
     3001 tagaaggagt gcttaattcg aaattactta ttttctcatc ttggaccaag ataaatttat
     3061 agatagtatc tttttgtgtt tttcttttaa aaacacaaca gagtgtgtta taaggaacgt
     3121 tataattttc atcagcctca ttttttctcc attcaaacaa atgataaact gcaaccaagt
     3181 tgccatcaat ttcatggaca gtgctctcgg taacatcctt taaagaacta tcaagggcta
     3241 atttatagta actagagaga ggaagtaaaa ttgtcgattt actgagatgg ttatcgtcta
     3301 tacgtgcaat catacctaaa tcaactaagg ttttattcca ggtgtttata gttttagttg
     3361 tcactcctag agactctgct atggtattga ccgaatgcca ggaatccccg ccttcattct
     3421 ttgccttaaa acagtaatac agatataaat taatagcttt gttattcggt aaatattttt
     3481 caagttctgt tggtagaata aagtaagaat ccttaatgtt ttttctgaac tgtctccagt
     3541 ctctgtagtt ttgtttataa agttgtgaaa cggtttttcc acctttagaa agtcctgcta
     3601 tcttaaccaa tcttattgct cctttcttga atctgtcatg atcatacagt attttttact
     3661 tgtagtccag caccttaata tattatccta tgtaattaat ttcgtactag atagtaatta
     3721 ttttttattt aattctctag tcacttacaa ataagttata taaactacga ttaataaatt
     3781 attacaaaaa ctattaagaa aacttctaca tacaactatt acaaaactat taagaaactg
     3841 aatactccta ttttttgttt ttaaggaaag ttttttcttt tttgaatttc ttattttttt
     3901 ctaatataac taagcaaaac tggataatac gacacttatt ttcaaatttt cacaagacta
     3961 atagtaaata tccatttaat aaagtgatac aatgtgttga ttttacaaat caacagaaga
     4021 agtagggaaa taacttacct atgcttcttt ttttgtacat ttaatcgatt cttctttaca
     4081 aaaacgaacg tatgtttgta taatgtggaa gaatggagtg ttatttatga tggattattc
     4141 aaaagagcca gtaaatgatt actttttgat cgatatgaaa agcttttacg caagtgtcga
     4201 atgtatagaa aggaatttag atccattaac gactgaatta gtcgtcatga gtcgagcgga
     4261 taatacagga tcagggttga ttttagcttc ttcaccagct gcaaagaaga agtacggtat
     4321 ttctaatgtc agtcgaccac gagatctacc gcaacctttt cctaaaacgt tacatgtcgt
     4381 tccaccacgc atgaatctct atattaagcg aaatatgcag gtaaacaata ttttcagaag
     4441 gtatgtagca gacgaagatt tattgattta ctcgatcgat gaatcgatct taaaagtgac
     4501 cagatcaatg aatcttttta cgactgaagg aacaagaagt caacggagaa agaagctggc
     4561 tcaaatgatc caggagaata ttaaagaaga gctaggattg cttgctacag taggtgtcgg
     4621 agataatccc ttattagcta aacttgcttt agacaatgaa gcaaaacata atgatggatt
     4681 ccttgctgaa tggacgtatc aaaatgttcc tgataaagta tggaatattc ctgaaatgac
     4741 agacctttgg ggtattggat ctcgaatgaa aaaaagactc aaccaaattg gtatcatgag
     4801 tattaaagac ttagctaatt ggaatccata cactattaag agccatttag gtgtgattgg
     4861 cttacagctg tattttcatg cgaacgggat cgatcgaaca gatatagcga tcccaccaga
     4921 accgacaaag gaaaaatcat atggtaattc acaagtgtta ccacgagatt ataccaggag
     4981 aaatgaaatc gaactggtgg taaaagaaat ggcggaacaa gtagctattc gtatcaggca
     5041 acataactgt aaaacaggtt gtgtccattt atacattggc acgtcgatct tagaaacgag
     5101 accaggtttt tcacaccaga tgaagatccc tataacagat aatacaaagg aattgcagaa
     5161 ttactgtctt ttcttgtttg ataagtatta tgaaggacaa gaagtaaggc acgttggaat
     5221 aacctatagc aagcttgtgt acactgattc gcttcagctg gatttattta gtgatccaca
     5281 aaagcaaatt gacgaagaaa atttagataa aattattgac aagattcggc aaaaatatgg
     5341 ttttacgtcg attgtacatg cttcttctat gttagaaggc gctcgtagta ttactagaag
     5401 tacattggtt ggtggccatg caggcggcgc aggagggctt aaaaatgatt gattataatg
     5461 atcgtggacg tttaaagtgg gcaggttttt atttatctga tcatactgaa aaaattgatg
     5521 ccgacaatga acaacgagcc aatcaaaatt tggcaaaaga acaaatgacg actgaagagg
     5581 ttgcggaagt attgaacgct gcagtcataa aaaatagatc agtatgtatt caaaaagaag
     5641 aacgaaacgc tgaaggatac tatccagaag atattgttag caagatctta ggtagtgatg
     5701 agctggggat ctacgttgga aaaaacaaag ttcactacga cgaaatacgt catatcgaat
     5761 tttaccagga taataaatgg ggtcgattag aatgaacatt atccagcaat atgagctaaa
     5821 gtatataacc tttgatcagc tatcagaaga gatttggggt tatggccagc gtttgataaa
     5881 tgaggttggt gttgaacgct tctctttcta tgtagaagct gcagcaggat accataaata
     5941 cgaatactat attggctatt aaagtgcaat aaaattatat ttcttttatg ttttacattt
     6001 tgtatcaatt ctgataaaat tacctatagg taattaaaaa atataaaaaa actagttaca
     6061 accttaggac gttgtaacta gcttgaagca tactagagct aactaaaata gcactagaaa
     6121 gcaatgttaa acccgtccaa caaacttgat ttaacattga gaccagctta ttcagctaaa
     6181 tatagttgaa taagcttctt ttgttttaaa aaaacaaaag gtgtactacg aataacgcaa
     6241 gtaaaagaaa tactattaca accagtaggc tacaagtaag tattactaaa cattgcgtag
     6301 ttagaacctt tgctctattg tctaaagcca caaaattaga gatcagcttt atgatgctaa
     6361 gagcgagctg catccatgcg gacataggtt cttttgacac tattaattct cctttttagg
     6421 ataagggaaa ttgctagtag ttttttcatt agcaccatcc cccttcattt gattgagtct
     6481 agtgctgctg tgatagtttg ctgtttaata tgcttacatt cttattataa cataaatgaa
     6541 acaaacacat ggttagaggt cgtatcaatc aaaatagtgt ctcacaaacg atttattact
     6601 tactcctgct gactaacgga ctgttcttca gtaactgtaa ctatatgttt gttaaaacca
     6661 ccattacctg tagataaaaa ccaatatatt tactatactc actatattaa atatatttag
     6721 tatagtaaaa actagaaaca ataaaatttg tgaatgttgt atacccccaa acaatacaca
     6781 tattttgaag gattaggatt aataaagcta aaaatatagt aagtatacta aatatattta
     6841 ctatatctag tatacttact atattttaat cttttgatcg tctattatat ataatccgtt
     6901 cctcgtcgtt taaagtatca acataggcgt ccattgcaag tttgactatt tcatacatag
     6961 gaatatcttt tgcataacta agatcccgaa tggtttttag tacgggagga tctacttgaa
     7021 ctggttttct ttctttcgca gtgtactttc gttcccctaa ctcgacatta atatcatctt
     7081 taattgaaat atcttcagca ccaattttct tcttatcttt gttcgttggt aataatgcca
     7141 tttagtttaa tctcctttcc aagaggtagg atatgattgg ccattgagtc agcatattta
     7201 ggtgtataat caaatccttc aatatcacca tgttgttcat agtattcaat tctttcttct
     7261 aattctgtaa agatgtctgc aaaaatagcc caccatcttc gatctacata atcatttaat
     7321 tggataccat tctcaccata catttctaac cgatccgagc ctttaacaat gcttttaaaa
     7381 atgtttgatt caccatactt atcaattgtt ttttgatagt ttgcgtgttg agaggaacgt
     7441 cgcactgaga aaagaacagg caaaattcca atgatttgaa gatgagactc ttcaaaattc
     7501 gtgacaatcg gaactaaaac tttattaata aaatcttctg ttccttccat tgcgtaccgt
     7561 tttaattctt gcattgcaat aatataatct gcagcagtta agaatgcacg aaccacatta
     7621 tctgttgatg gtgggcagtc gataaagata taatcgaaat tttttctcaa ttcttctaaa
     7681 ggtttaatga aggccaatga tctcttacga cgatcaggat atttttcgga caagtattca
     7741 ttaagttctt cagatccagg agagccagcc ataatatata aatgtggact tacttgagta
     7801 atacctgaaa cccagtcccc ttttttgatt gctgcagaca tggatcgatc aaagctagta
     7861 atttgatacg ttgatccaat gttggaagta gtatttcttt gttggtcata atcaattagc
     7921 aacacgtctt tttcaaaaag ttgactagaa acaatcgcta ataaatcatt gtctgtagtc
     7981 ttaccaatgc cgccttttct acctgtaagc attacaactt ttcctagttt atctgatgtt
     8041 ttaaatgcag tccgtaagtt ttccatagtt ccctccaatt tcctatacta aatatattta
     8101 gtatacttca tatacttaat atattcgata tatctaatat actccaaatt gataagaatt
     8161 cagactttat aaggaatata gtggatatac taaatatatt tgctatattc agtatatcag
     8221 atatattcaa aatgtcaaaa tatatttgtg cgttttgcgt tgacaattta gagtgaaaag
     8281 aggtaaactt aattctatag aaaccacaga taattcacta tttacaaagt agcaaaagca
     8341 gtggtactct ttaaacagaa aaattacata aaaaaaagag acggaaataa ttgattttag
     8401 cagaatcaat tatttctgaa tcacatggtt aggacatgtg ttcacgctcg tctcaagaat
     8461 atgtaagtag ctaccaacta cttatattaa aagttgatcg gatacctttt ccgattgcct
     8521 ttattctacc aaaaaaaggc gagcaactca acagaagaac gtttatttag tgtacttaaa
     8581 ttaaatattc ttaaacactg aagagagaac acatactatg gctgagatta aagctaaact
     8641 gtgttctctt tttgtttgag aaaggacgtt acaatcgatg ttgagcgaaa tttattcagc
     8701 tattcttaaa aacggcttac gtacatacaa atatcgaaac agcaccatga aacctgcagg
     8761 tcatattgat tccagtagga gtggtgctat ctttgcgtac cgtagcaagc aattaatgaa
     8821 tgttgggcgt ggtatggtca ttacttcgga agaagctatt ttagagaacg aaaagaaact
     8881 aacgcattgg acacctaata cctatcgctt tggtacttat gcggatgatt atcgaacagt
     8941 ggttaaaggt cattctgaga aaaacttaag tcaaatcaac acatttgtag ttgatatcga
     9001 ttcaaaagag aaccatcaag gcgaaattat tttagcctgt ttagatcaag tgggctacat
     9061 gccaacgcta attttagaat cagatcatgg ttatcaagtt tattttgtac taaagacacc
     9121 aggctatgtc acaaagaaaa gcaatttcaa ggtgatcgat gtagcaaaaa aaatttcaaa
     9181 aacaattcgt ctacagttgg ctgaaaaatt gtccggagtg gatctaggat gtaaccactt
     9241 cggaattgct cgattcccac aagaaaataa tattgttttt aaagaaatga actatcagta
     9301 ttcttttgct gactggattc aatggtcgat gaagcttgaa tcagatcaaa aaacaaaaga
     9361 agatcgagaa cgaaaactaa ttgtctttcc tgagaaaaaa gaaattcgtc aagtagatga
     9421 accgtggttc gatatgttac ttcataaagc aaacatcgtc ggcggagaag gacgtcttgg
     9481 tcgaaataat gtgattttca cgctttcttt agcttattac tcttcaggtt atgcattgga
     9541 tacttgcgaa tacaatatgt tcacattcaa cgaacggtta caggaaccgc tatctgaagc
     9601 agaattagta aagattgtac gtagtgctta ttctggtaat tatcaagcag caagcagaga
     9661 attcattatt gaattgtgcc agcaatgggt ttcaccaacc ttaaaaaata atgatctgtt
     9721 cattcaacga cgtggctggt ggaaatttaa aaagccacga gatcaaagaa aatatagtca
     9781 taaaaatgaa tggaaagaag atctattggc ttatctaagc gaaaaaagtc ttgctagtga
     9841 gccttatttg aacctgtcaa aaaaagaatt ggcttcacaa ctaacgatgc ccaagcgaac
     9901 acttgataag atcttaaatg agttacgaga ggagaataaa gtcttctaca aggtaacacg
     9961 aggaagaaat ggcggaatga tcattgcttc agtcaaaacg ttgttcgcga gggttattca
    10021 actaagtaaa gaaaagagac tagattattc aacaaggatc acagaggtat ttggactcaa
    10081 cgagagctta gtagaagaga catttagaca attatcaacc cccttgaacc ctcttaaaga
    10141 agtgaatctt tttgaagtag atacaggttg aaaaataaaa ggtgcaaatt gccttataca
    10201 atatatctat gatacttctg taggtgttgc tccctttgcc tagctacgtg taggtggtat
    10261 acttataact gcgtatgcag tcttatgtat catggaggaa gttgtatgtc gttaaaaaat
    10321 tatgtctatt cacatcctgt taatgtgttt atcattggtc gtttgggatt atctgtggaa
    10381 gtgttctgtg agctttatgg ttttaagcag gggactttgt cttcttgggt taccagggaa
    10441 aaaacagttg cttctttgcc gattgagttt cttcatgggt tgtccttagc ttctggggag
    10501 actatggatc aggtatatga ttgtttgtgt gtgttagagc aggagtatat tgagtataaa
    10561 atagctaacg agttaagaaa aaggaagaag tatatccagt agtagttttt atttacttaa
    10621 aaaattggtt cattgagcaa cctatcgctg ctaaagtagc aaaggaaaac gttaaaggaa
    10681 agaatttagg gaagaaatcg aaatgaaatc ggacgactgg attgaacaca actggcttcc
    10741 tctgaaaaga aatagcaaac gaaagaaatt ttgggtattg caattatggc cattaggaaa
    10801 actttgtagt tacggggcac gacttattct tgatttaacc gtttactcga ttggagtatt
    10861 tggaacggct tattacttga taaatgatcc caataggatt gcagcatcag acatttttac
    10921 agtgctaatg acgttgattt ttgtcatgct attgtctatt tttactcaat tagtcatgca
    10981 atttaccagg caaaaattaa cagcaggaaa acttttcaaa agcctattcg atttaattgt
    11041 tgtaaatgca attctagcga ctttaataaa acaaattgaa caatctggaa gaacaacaaa
    11101 aggagtgaag gattttttat tgacgtttat tcactttgta aatggacaca tgtatttgtt
    11161 tgaagtgggt attattctct tttttgtcgg gtatgtatcc acgaaactta ttaaacgttc
    11221 aattgaaaaa gaaattgaaa ttgacctgat tccgacactt cttggttatg agtacaatgt
    11281 tgattttgga agatatgacg aattgatcaa tacggatatc gttcacacga gtatccatga
    11341 atctactgtt aagggcatca gatctatttt aaaaaatggc caggaaatga aagcaataga
    11401 tcgaagaaaa gagatctaca atttttatga agtcgaagca agcctacgat atggcatcgg
    11461 aaaattgtgg ttagatggaa gtaatattcg tcaaaacaaa ccatacattt tttggaacag
    11521 tagtgattta gaacttccaa tgaaagataa ataattatgg agaatcgttt gaaaatgatt
    11581 cctctataca ggattgtgct tatagttggc atggagttaa aaaccttaaa gaaggagcag
    11641 ttattcaaag tgaaagaacg tcataatcag ttactatgta gtaaaacggg tacgatgaac
    11701 attgaatacc gaacagaata tttagaatta acgaatcaaa ctgatttttt gttgattcga
    11761 aagcaacaag agcaagaaaa aaattaatgg ctacttatag ccaattgatt gatgaatggg
    11821 aacaattcaa ggaatctaaa attccagaac gtctctaaaa gcctttattt gtaaagagca
    11881 taaggaaacg tgggaacact ttttaaaaaa agtgttccaa taggctgtgc ctattacgtt
    11941 tctcaaaaat aaatgtggga acaaaatatt taaaaatagg atagtgaaag gatagtgaag
    12001 gatagtaaaa ggagggtagt aggatagcaa aaaggatagg ctccttttcg ctatcctttt
    12061 taaattggag gaattaatat ggaagtaaga ataagaaatg tggatgagaa aatcgtaaga
    12121 gaaattgatc gaagatgtga cgaa
//
LOCUS       DADGKS010000079        11526 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.080, whole genome shotgun sequence.
ACCESSION   DADGKS010000079 DADGKS010000000
VERSION     DADGKS010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11526
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.080"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..734)
                     /locus_tag="JXV47_002380"
     CDS             complement(<1..734)
                     /locus_tag="JXV47_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase family protein"
                     /protein_id="HAX1488394.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEK"
     gene            complement(1149..1919)
                     /locus_tag="JXV47_002381"
     CDS             complement(1149..1919)
                     /locus_tag="JXV47_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1488395.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(1912..2847)
                     /locus_tag="JXV47_002382"
     CDS             complement(1912..2847)
                     /locus_tag="JXV47_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1488396.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(3163..4812)
                     /locus_tag="JXV47_002383"
     CDS             complement(3163..4812)
                     /locus_tag="JXV47_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAX1488397.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(4929..7532)
                     /locus_tag="JXV47_002384"
     CDS             complement(4929..7532)
                     /locus_tag="JXV47_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAX1488398.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(7544..8593)
                     /locus_tag="JXV47_002385"
     CDS             complement(7544..8593)
                     /locus_tag="JXV47_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HAX1488399.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(8619..8933)
                     /locus_tag="JXV47_002386"
     CDS             complement(8619..8933)
                     /locus_tag="JXV47_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HAX1488400.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(8949..9395)
                     /locus_tag="JXV47_002387"
     CDS             complement(8949..9395)
                     /locus_tag="JXV47_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAX1488401.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(9396..11372)
                     /locus_tag="JXV47_002388"
     CDS             complement(9396..11372)
                     /locus_tag="JXV47_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HAX1488402.1"
                     /translation="MKIEIIIVHLSCIQEVKIMGIEFSERQMKILYFLIENEHTTYKE
                     LSEQLYVSTKTISKDILILKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKIN
                     IADSPEDRLTYVFAKLLNTNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLV
                     SDRNGVRIKADEKSKRRLMSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDI
                     LKKVAELLNRYMNKTQLKFTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNT
                     LILIKMIEKAFSIIVPIDEQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVR
                     IKLNEFYPDEELINNLVLHLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEE
                     IEERFCIHFNEDEIAYVTLHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFA
                     DMVEIEDVLSINELQDRKVTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQL
                     NEQTEDAFLNLLDKRFCFFTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKL
                     SSTAMNDFAMPHIEVDFIKKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKI
                     YETFNEIASNHELLANLKTSSSFEKLVYILKEGL"
BASE COUNT         3432 a         2394 c         1815 g         3885 t
ORIGIN      
        1 tctttttcaa atgcataagg attcttgaaa atcccccggc caatcatgat gccatctacg
       61 ccatattttt cggccaattc ttctcctgtc tggcgatctg ggatatctcc gttgatcgtg
      121 atcagtgttt gcggagcgat ttggtcacgt aaagcaatga ttttagggat gacttcccaa
      181 tgtgcatcta ctttactcat ctctttacgc gtacgcaaat ggacagaaag attggctata
      241 tcttgatgaa gtaggtgact gatccattct tccatctcag acatttccgt atagccgata
      301 cgcgtcttga cgctgacagg caaaccgcca gctttagccg cttcaatcaa ttgtgccgct
      361 acttctgggc gaaggatcaa gccactgcct tttccacgtt ctgctacatt agggactggg
      421 cagcccatgt tgatatcgat tccttggaag cccatttctg ccatagcaat gctcatttct
      481 ctaaaaaatt ctggcttgtc tccccaaata tgggcaacca tcggctgttc atcttctgta
      541 aaggtcaatc ttcctcgtac actgtctttt ccatctggat gacagaaact gtctgagttt
      601 gtaaactcag taaagaagac atccggtgct gctgcatgct ttacgacatg gcgaaataca
      661 acatctgtta catcttccat tggtgctaaa acaaaaaaag gctttggcag ctctttccaa
      721 aaattagtag tcatttattt gttactctcc attctatcaa gcagtgaagt cgcaatcttt
      781 ctcaaaaaca ttgtcattat actaggaaac aaaaaaagaa gcaaagtgaa cagcttaaaa
      841 gatgtttctg attgagcaaa aaaagactgt gacaaaaatc ttatcacaat tccttttccg
      901 gaataaatgg tgttcaaaag cttgcatctg cggtaataag tccaaccaaa cgaaaaatag
      961 gaggagctat ttttgtttgg ctgttcttat tacttgatgc agaacagctt tttcacaacc
     1021 tctccactaa acggtgttca atcagctgac cctcggtatt agctcaacaa acgacaaaat
     1081 atgaggaact attttcccgt ttgtttctct aatactcagg tcaaaacgct gatttcacaa
     1141 cctcttttct aacttctcaa tcctcttcct ttattgatca aataccaagt aacggcgtac
     1201 aaaacaacga tgaatagcac aagtacgatc atcgatgttg ctactggcac atcgattgtt
     1261 ccaaggaatc cgtaacggaa accggagatc atataaacga tcggattgac tttcgaaaca
     1321 gcttgccaaa atggcggcaa catagagatg gcatagaaaa cgccacctag ataagttaac
     1381 ggctgcaaga caaatgtagg cacgatcgat acatcatcat aagactgagc aaaaatcccg
     1441 ttgagcagtc ctgctaacga aaacaagatt gccgtcatca ataatgtaat gatgaccatg
     1501 aaccatgaat acacatgaag tggtacaaag aacaaggaaa tgatcgttac gagagagccg
     1561 acgagaatac tgcgacccac tccgccaatc acaaagcccc aaatgatcac atgcgtagga
     1621 acaggcgcta ccaagatttc ttcgatgttt ttctggaatt tttgagagaa gaaggacgaa
     1681 gaaacgttgg catacgaact agtgatagca gacatcataa tcaaaccagg cacgatgaat
     1741 tccatatatg aaaaaccacc catgtcaccg atccgaccac cgatcatttt tccgaaaata
     1801 acaaagtaca aggatgtcgt gatcacaggc ggaaccagtg tttggaccca gatacgcaaa
     1861 tagcggttcg tttccttgat agctaaactt tttaatgcag taaaataaag attaaacatt
     1921 tttctcctcc gtatgattat tttcttctgt gattttcaaa aacagttctt ctaaacgatt
     1981 cgacttattc ctcatagaaa gaactttgat tccttgtctt gtcagctgat cgaagattcc
     2041 gttcacccct tgatttcgtt caacttcgac agcgattgtc tgttcatctt caaatgtaca
     2101 agcgtatcct tcaatcacag gtttggtctc atatggcgct aaatcaaaga taaatgtttc
     2161 aaattgcagt ttggatagaa gctctttcat actagtattc tcgatcagtt cacctgattg
     2221 gatgatcccg atgttgcgac aaagcatttc agcttcttct aaataatgcg tcgtcaaaat
     2281 gatcgttgta ccattttcgt tcaattctcg gagaaactcc cacatctcgc gtctcaattc
     2341 aatatcgact cctgctgttg gttcatccaa gatcagcaaa cgtggttcat gcatcaatgc
     2401 cctagcaatc atcagtcttc gcttcattcc cccggaaagc atacgtgcac ggacatttct
     2461 cttttcccaa agattggact gcttcaaata tttttcgctg cgtttcatcg cttctttgcg
     2521 agagacaccg tagtagcctg cttgattcac gacgatttgc tggaccgttt caaagggatt
     2581 gaaattgaac tcttgcggga ctaatccaat ctgttgcttt gctcggacta gatccgtatc
     2641 cagatcataa ccgaagacat tcacttttcc agatgtttta ttgactaaag aagtaatgat
     2701 tccgatcgtt gtagacttcc cagctccatt tggtcctaat agcgcataga aatctccttc
     2761 tttcacggaa agatcgattc ctcgcaatgc ttcgacccca cttccataaa cctttttcaa
     2821 attatttatt tcaagcgcat ttgccattta tttcctatct ccttatagac atgattcttt
     2881 attgtatcat ggaatacagc agatgaaaaa acaacttggt tccagcgaaa aatcaggttg
     2941 ctgggctcag gaaaatctcc taatgaaaga catcaatcgg acgaagtcag acaacctttt
     3001 cagaaaaaac aaatcgaaga taaaggatta ctattcatat gtgcaacaaa aggagcgtga
     3061 gacaaaagta aagaacactt ttgtctcacg ctctaaacac gtataaacgg cggaagcaaa
     3121 agccaagatt tttgatccaa taaatacttt cgatcacttc gcctatccca atacatgcca
     3181 ctgccgcttt tcatcaaata acgcggcttc cgtttttgcg gtttctacta aagtctctgg
     3241 gtaatccaaa actttcagca aggcaatcgc atttcgggtc cttgaaggtc cttcttttaa
     3301 tttgaaatca aaactgattc cttttccttc tgttacttgt tcttcaaagt ggacattctc
     3361 acaataattc tttaaaatct ctgtcaattc gatatcatgt gtggcgacaa atgctaaaga
     3421 tggatactcc gcaagccacc gaacgactga agcggaagaa gcaatccgtt cgatcgtatt
     3481 tgtccctttt aaaatctcat ctacgaagca gtagcagcgt tctttggaag ccacttggtc
     3541 caacaaacgt ttgatcgatt tgatttctga aacaaaataa ctgtcgcctt caaataaatc
     3601 atcttcgatt gccatggaag tcaacacatg tccaggttgc agggtaaact gttctgcaat
     3661 cgctgtttgg atcgtctgtg ctagaataca gctgatggct atacttttga catacgtaga
     3721 ttttcctgat gcattggaac ccgtgactaa tgtattcttc tgccagttga ccggattcac
     3781 taccgcttct tttaacaatg gatgatagat atctttcgct gtcacaccgc cctcagtaaa
     3841 ctctggtcgg caagtgatgg gcatataagt acggtaattc aatattgcag cggctacttc
     3901 taattctccc agcaattccc acagcttgat ggcttcagtt gaatgctttt ctaatttagt
     3961 gagaacgaaa tgataggaga taaatggcag catgaacatg atgttgacat attcaaaaat
     4021 caactctgct tcactcccac tcttcatacg aaatgaaaaa cctaatttag ggatgtctct
     4081 taatggttta gtttgctgtt tcagctcttc ttgaagtggt gtcggcagtt ttgctagctg
     4141 attggcggct gaaatcgttg aaaccaaata actcatgcta ttcagctctg tttctagtgt
     4201 ttgtttcttc actagataat agaccgtatt gaatactaac ccaccgattg ccaaatagat
     4261 tcctagtact tgtcctaaaa gaagcaaacc caaacccacc agcggaagca agccaagaaa
     4321 aataaataaa cctacgcgtc caatcttttt actttttcca tccgctagat attgttttgc
     4381 aaaattatga tctttttttc ctaaacgagc gaattgatat tggatttttt ctctcagttg
     4441 aggattttcc tgataaaaag caatcagttt ttctaactgc tgatcttcac caaaatcaaa
     4501 gctgcgtaaa cgttgataca acgcttctga acctacacta gaataggtac tgttgattcc
     4561 ttcgaatact tcgaacatat ccaggtcata ccaagtaaga tcatcgattt cgctatccca
     4621 tgaacggaac ttcttctccg tgagccatgc ttccttcaag ctttcttctt tatcaaatct
     4681 cggttgataa ggaatttttt cccatttgct acgaactgtt tcctttaatt tcaaacgtga
     4741 aaaaatgtct aaagcaacta ataaaataac agctgcaata ataattaaaa cgataaattc
     4801 tctttgaccc atatccctct ccgttccttt atttgttagc tttagtatag cactgttgcg
     4861 ctatttgaaa agagggtaaa aaaacacctt tcaaaataaa aggtgttttt ttcttgtata
     4921 ttacatattt atctctcatt tatcaaaatt gacaaataat catagggagg aattgttgtt
     4981 aattcttgtt tattctccag tgcattgaca actgtcccaa gggaaaggat agcctcaggt
     5041 actatttttt cttgttctgt tggattagct aagcgaagaa caaatccttg ttcatgaaaa
     5101 taagaaggat aaatcgatga tacaattaag tcttcaggta attcaatcaa tgaaaattta
     5161 cgaggaacat caagttcatt ttgtaatggc caaatcttgt tatctaacct gtgaataaat
     5221 acattcagtt tctgcttttg ataagaaata gattgttcta accgtttttc tgcctgtttt
     5281 gccactttga actcattaaa tcttccttct tctacattaa atccaaaagt gactttatac
     5341 tcacctatct cttgagctag cggtgtttcc atcatgacat gcccttcatt tgtcgtatct
     5401 cctgaagctc gcccaggtcg ccaagcaaga ttaggttttc caagttcccc tgttgttgaa
     5461 aataaggtta tgattaattg attttctata cgttcatact cttttaaacc atctgcataa
     5521 aacgtaaaat aatgatcatt ttctgccaca gagacactct tatcgaatat ttctaaatta
     5581 acaggtttct ctaccatagt ttctgaccaa ttcggaggaa tgacatcagg ggtattttca
     5641 ataaatccgt tttgaatttg tgcaattgat ttttcagatt tatctaaaac attaattgct
     5701 aagcgcatac gatgcgagta aacagtatta tgaattttga gtgtgccttc aacgatttga
     5761 ctttctccca gactgaacga tatttcataa gatatttctt ccatttcggg tttttcagat
     5821 aaacgatctt ttaaatcttt aggaagttga gcttttccgt aaacaactaa tgtttcttgt
     5881 aaagaatctt tatatacttt agctgtttct aattttagag atagttctgt atctccttct
     5941 aatggtgaat aatcatacgt atcgccatca tttgctgaat cgatcaaatg aacgaaatca
     6001 agatattgtc tatctccaac tatcaaattc aattgcccat ctttaaaaga aagtttatat
     6061 ttattgttac ttatctcagt tttgtctatc tcgattgctg tttctaattt ttcattattt
     6121 ttctcaaatt caacaacagt gtatcctagt gctggcacat ttacatttat ttttatgtca
     6181 agttcataat aagctggttc atcaaaatat tcgaaacctg tagcaatcat ccgataagca
     6241 tttttccgtt ctggaaaata aacttctttt tcaatgatat tatagggact acctttgaag
     6301 tgtattttct ttgaatcagc tactacatgc acgattttcg atccactata attctcagtc
     6361 gttgtgttga aaacaaggac ttcattcgat tttagcttta atgcatcagc catccgtttt
     6421 acaataaggt tttcgattcc gtcagctatc tcattagctt ctttgattcg atggaaaata
     6481 tcttccgcaa cattatctga aacacagcca ccaatactat catgagcctg gttttgcaaa
     6541 atctttttcc ataaccgacg aagtaggcct ttactgatat ggataccatt tctttctgca
     6601 atcagcatga gcggctcaac tcgttttaga attttttgtt ccaatttaaa attttctatt
     6661 ttcatttttg ttcttactga gccaatagaa cgatgaacac gagagtaaac cggctgacga
     6721 agttcacctt tatattcagg taattctttt ttgtttctga taacttctac ataagaagga
     6781 taatctgaaa taatattgtg gaatttactg tatttattca acttctctac gacttgatca
     6841 aaatttaaaa tcattgactt ttgatctaca cccgaaggta ctaaaatatc tttgtttttt
     6901 ccttgcatat gaagcatttc aactgcttca tccaactttt cttttgcaaa ttcaggaata
     6961 tctttaattg cgtctaaggt catcattcca gtcatataac caaatggaaa attcatggca
     7021 taaacaaatt tatctcccaa tcctttccag ataaaataag gagatggaac catcgtttca
     7081 aagtttaatc ctcgccaaca catgaaatta tcgatttcta cttgatgcaa aagtgtaggc
     7141 aaattcgcat tgaacccaaa cgtgtcaggc aaatacccta ccatcattgg atctccatat
     7201 ttaaggatcg tatcactgat tccaatcatt aagtttctta aaattgattc agcatccact
     7261 aataaggcat ctgtttgtgc ataccacggt cccacgaata gttgtcctgt tttcatcagt
     7321 cgttggataa ccttaagctt ttgcggattg atctccaaat actcatcgac gattgaagtt
     7381 tgtccatcta aacaaaagtt tactttaggg ttcctttcca attcatctag aacttcagta
     7441 aagacctgat cagacaatac gatggcatct tcatttgtaa aataccattc tctgtcccag
     7501 tgcgtgtgtt gaattatatg tgcatttacc atatcagatt ctcctacttt ccttcttcta
     7561 ctgaatttac ttgttgttct tttttatact tgatggattt tagtgcattg accattaacg
     7621 ctgtaaccac tcccccaata acaattgata ctaaatataa aggtatattc gtaacaaaag
     7681 gaattgccat aaaggttgaa agcattgttt cttgagtaac accaaaaaat ccatttagac
     7741 cacatgctac tgcagtgccc accacgatgc ttggtattac tcgtaaagga tctttcacgg
     7801 caaacgggat cgtcccttca gtaatcccca caaggcccat aatcatagct gtctttgcat
     7861 tatctcgttc cgattcatca taaagttttt tgtttaaaat tgttgctaaa aacattccaa
     7921 atggcggaat agcaattcct aataacatgg ctgtactagg tccaaagctt ccgcttgaaa
     7981 aagaagcaac cccaaaagca tatgcgattt tattgatagg tcctcccata tcaaacgcca
     8041 tcattcctcc taaaatagcc gacatcaaag cagcatttgc tcctgacatg ccttctagcc
     8101 aattagtcag tcctgttgtc attgcttgaa taggcgtagc tagtacatac cataatatga
     8161 ttccaacaac taatgtagta acaaaaggaa tcagcataat tgattttaga ctaataactt
     8221 gcatcggtac ttttactttt ttcaatgcat tagctaaata gccacaagct aatccagcaa
     8281 ccattcctcc aataaatccc ataccaagat tttgacacat catcccagtg ataaaagctg
     8341 gtgctagacc gggacggtca gcaattgaat atgcgatata ggctgaaatc atcggtacga
     8401 taaactgtaa tcccgtctga ccaatcattc gcaggactcc ccagaatgta tccgtctggt
     8461 cccaaacacc tgtgccacca aaaatgactg caatagaagt tagtaaccct gctgctacga
     8521 caagcgggat catataggaa accccacttt ggaaatgatt tagaatttct cttccttgtt
     8581 tcttgaattc cattagtaac tcccccacga tatatttttt atttgttaat taatgcaatt
     8641 gcttcatcaa tcgtctcttc accatctttt actacctctg aggtccctac tgttaaaatc
     8701 ggtttaccgt caaagcgacc tcgttctgaa acatttgtat ctactgcaaa tatgacaaca
     8761 tctgcctcgg aaacatccga aattgaaagt ttgttttcta tccccatagc cccctgtgtt
     8821 tctactttaa tatctaaccc tttcttcttc gcaaactttt ctaaattagc ttttgccata
     8881 taagtatggg caatccctgc gatacatgct gttactgcta ctatttttgt catatgaaat
     8941 tcctcctttt aaaatgatag agcttttacc aattcttttt tatttctcga atcttttatt
     9001 cttttaacaa actcgtcatc catcaatctt ccagataatt ctgctaaaat acgtaaatga
     9061 ttagtacctt tatcagtgtc ttttattgct aacaaaaaga cgagatcaac tggttgatca
     9121 tctaatgcgc cccattcaac agaccgcttt aacttggcta cagccactgt tgattcaatt
     9181 actgctaggc ttttgccatg aggaatggcg atatttttcc caattcctgt ggtcatatgg
     9241 ttttctctgt caaatacgtc tttttgaaat tgtttgtggt cagacacaaa cccattagtc
     9301 tctaacaatt tcgataattt ttcgactaca ctttttttat cagatgcatt taaatctatc
     9361 actatattat ttatattgat tttttcactg atcatttata agccttcttt caatatataa
     9421 actaattttt caaacgacga actcgttttt aaatttgcta ataactcatg attcgaagcg
     9481 atttcattga atgtttcata aattttattc aattcaggtt ttactttttc attaagtgca
     9541 aaaaagaaaa cagaatgaac aagtgtccca tcccaatcaa ttccttctgg attaacgtag
     9601 acacagatta ctggcttttt tataaaatct acttcgatat gcggcatagc aaaatcattc
     9661 atcgctgttg aagatagttt ttctcttttg attgctccct ctagtatccc ttctttcgcg
     9721 taattttctt ttaccaattt tttggtaatt atatttaaaa cgttcacttg attatccttt
     9781 atttggtggg taaaaaagca aaatcgttta tctaataaat ttagaaaagc atcttctgtt
     9841 tgttcattta actgtagata ctgttttact tttctgacat ctgcccctaa catcaaagga
     9901 ctaacaacaa taacaggaaa atttgtattt tcaatcggaa tcgtgcttat aacaagttca
     9961 tcagtgactt ttctatcttg tagttcattg atgcttagta catcttctat ctcaaccata
    10021 tctgcaaaac cgttatttat tctttgctct aataattttg atgttccata tccgctacta
    10081 caaactaata tcactttcgt tttgtcaggt ttgtaacgat ccaaaagtga ttgaatatgg
    10141 agtgttacgt aagcgatttc atcttcatta aaatgtatac agaatctctc ttcgatttcc
    10201 tctaataaat ctacacttat cataaatgac cttttaaaag aatatttgat tttgtccgta
    10261 taagggttat agatatttac tcccaatttg agtcttttaa ctgctgcatt gagatgtaat
    10321 actagattat tgatcaattc ttcatcagga taaaattcat ttaatttaat tcttactaac
    10381 tcttgtagct caacacccat atctaaatag gaaagcttcg tttgatctaa gtcgtgattc
    10441 atagcatttt tttcaatcga agtaatgtga atgtcaacat aagcttgttc atctattggc
    10501 acaataattg aaaatgcttt ttcaatcatt ttgattaaaa taagtgtatt ctttgagatt
    10561 tcttcttcag aattattact acgtgataag aaattgcttg tttcaatcct ttctatcgca
    10621 atagcaaggt ggatagctaa agtttgaaat tcataatctg taaatttcaa ttgtgtctta
    10681 ttcatgtatc gattaagcaa ttcggctact tttttcaata tgtccttatt taagaaatta
    10741 ttcgcttcac caatgaaatt gatattcaag tctaagagat ctgttttact gttagatgct
    10801 gtaaagccac cccaataata gttcacaact tctgacatca accttctttt acttttttca
    10861 tcagctttga tgcgcacgcc atttcgatct gaaactaagg acatcccatg cttgtttagt
    10921 ctttttctaa catctttcat tgtgctttct accgtcgacc tgctcacgta taattcgtca
    10981 gcaagatttt gaatctttag agaatcatta gtattcaata atttagcaaa cacataagtt
    11041 agacggtcct ccggagagtc tgcgatattg attttatgac tggataataa atttcgaagt
    11101 gtttcttttt ttccaataag cgaaacgcct tttttaggtt gaaccaacat ttgtacatct
    11161 ggcatttttt ggattatttc tttcaaaatt aaaatatctt tgctaattgt tttcgtagat
    11221 acatataatt gttctgataa ttctttgtaa gttgtgtgct cattttcaat caaaaagtat
    11281 agtattttca tttgccgttc gctaaattcg atgcccatta tcttcacctc ctgaatacag
    11341 cttaagtgta caattattat ctctattttc atacagaaga aagttcttga ttaatgtaga
    11401 agtttctaat attcttgatt atttcaaatc aataaaaaag cctgcaatat ttatatcaca
    11461 ggcttttttc tctattaaat atatataaga taatacattt ttctactagt tctcactaat
    11521 cttgta
//
LOCUS       DADGKS010000080        11410 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.081, whole genome shotgun sequence.
ACCESSION   DADGKS010000080 DADGKS010000000
VERSION     DADGKS010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11410
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.081"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(70..1491)
                     /locus_tag="JXV47_002389"
     CDS             complement(70..1491)
                     /locus_tag="JXV47_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAX1488403.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(1734..3611)
                     /gene="tdc"
                     /locus_tag="JXV47_002390"
     CDS             complement(1734..3611)
                     /gene="tdc"
                     /locus_tag="JXV47_002390"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAX1488404.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(3902..5158)
                     /locus_tag="JXV47_002391"
     CDS             complement(3902..5158)
                     /locus_tag="JXV47_002391"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HAX1488405.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     gene            5738..7039
                     /locus_tag="JXV47_002392"
     CDS             5738..7039
                     /locus_tag="JXV47_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAX1488406.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(7108..7707)
                     /locus_tag="JXV47_002393"
     CDS             complement(7108..7707)
                     /locus_tag="JXV47_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAX1488407.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            7962..8843
                     /locus_tag="JXV47_002394"
     CDS             7962..8843
                     /locus_tag="JXV47_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1488408.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            8856..10466
                     /locus_tag="JXV47_002395"
     CDS             8856..10466
                     /locus_tag="JXV47_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HAX1488409.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(10543..11202)
                     /locus_tag="JXV47_002396"
     CDS             complement(10543..11202)
                     /locus_tag="JXV47_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAX1488410.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
BASE COUNT         3325 a         2281 c         2075 g         3729 t
ORIGIN      
        1 aaaaactatt cacttggcag gacctcctac taaatcagcg acaaaacgtc ggctgaaaga
       61 cttatttttt tatttttctt ctaaactttt ttctacctca atcccccaag aatctttctt
      121 gaagtgattg atgatcaatg gaataacgaa catgaccact gtgatagctg ctactaataa
      181 tgcatcactc aatgtcgctg tacctaatgt agcaaatacg acaacgatga tagagaagat
      241 cagcatgcag ctgactaccc aagctaatcc gtttccgttt ttaccaattc ggtaaggacg
      301 ttcgaattct ggatgtttct tacgcatttt aagcaatgaa acagcaatca aaatgtacac
      361 gatacaataa ataacagttg tagcatttgt aagtgtcaag aatacagcac ttacgtcatc
      421 cattacacca taaagcaaag caaataatga aataacgatt gattgtgtta gaacgacatt
      481 tctagatacg ccgtatttgt tttctttatg gaatccgaat tttggtggaa ggaatccttc
      541 acgagctact tggatgattg tttttgatgg tccagtaacc caagctgata attgtaaaag
      601 cacaccaata aataccatga agctgaagat atttccgatc acttctggta agcctaggat
      661 ttgacagtca atcaagatag gctgcgtgat atttgctaat tccatttttc catctggtac
      721 gacatttgct acaagcatcg cattgatgac attcaataaa actaatccga tcaaagcgat
      781 aaatacgcct tttgtataat tttttgttgc gtctttcaaa cgaggcatgt aaacagaact
      841 catttcgatc ccaacaaaaa taaatgtgat accagctaag tatttcaatg aatcaatatg
      901 ttccaagtca gggaaagctt ttgaccatga aaagtcacct agatagccgt ttgagactag
      961 tccgactttg aaggctgcca aaacacctaa aacgaacatg atgactactg ggatatatac
     1021 ccctagccat acaccgatgt tcccgccgac ttttgccata tcgaatttca agttcaagat
     1081 cgtgatgatc cagtagataa ctaaaataca acctaaaacg aaccagtgat tattgccaag
     1141 ttctacatta ccaaatgtgt ttcctaacaa tggtcctaaa gtagaagcga ccattaccat
     1201 acctgggaac atttgcaccc ataatagcca tgcaacgaca aatccccatt tgctgcccag
     1261 tgctgttttt acccataact gaggaccgcc ttcttgagga agcatcgtgg aaagctcacc
     1321 ggaaaccatt gatatcggac cggcaaaaaa caaaactgca aaaattgaat aaaaaatcaa
     1381 tgtccaaccg actgcggcta acgtaggaat actccgaacc gttgcacaca gtgccattgt
     1441 cagaccgata aaggtcccaa gacccatttt acttacttca gatttactca ccgttgacac
     1501 tctccttgat tttttggata aaataacggt gtctttgaag tagtttcagc aataaacgaa
     1561 acaattcagc gaatatttga ggggattctt tgagtttatt gcttgaaggg tttcttcaaa
     1621 gacaacctca aaacaaaggg atcgaagagc ttaggtctcc ccttgctctt cagatccaaa
     1681 catgcgtcag aaacagttag tattcaagct gttttctaac atgattacct tgcttatttt
     1741 gcttcgcttg ccaataattg gtctgcgtag attttttcca atttttcttg aagagctgct
     1801 ttgatttttt cagcatattc ttcaaagtgt tcttctttgt tcatgtatgg tgtcattacg
     1861 ctggcacgca atacagttac ttttccggca cggttccatt cttcatctga gaatcctagt
     1921 tggttcacaa attgtaatgg gctgttgcca tagtctggga tagcaaagtc agtatgtgaa
     1981 gttaagaact cattaccgta aatgcttcct ttcacgtatg aagaataatc atatacgtca
     2041 tggttcaatt tattcattgc aactaagtca tcgttgcctt tttctttgaa tacatagtct
     2101 accatattga aatctggata agttaatgga tgaacttcga tttctttgtc tcctacttta
     2161 aatgacaagt cattcaagaa gttgtagaaa cgatgtgcac cttcgattga tgcacccatt
     2221 aatttaccat atcctgtgac attcaaaggt aagacatggt gtgctgccca aacgctggct
     2281 gctgttgccc ctgcttttga accttccaag atataagccc caagtaatgc tgggatatct
     2341 gcgccttttt caaatacata tgtcgcaaag taagagataa cgtctctcat gcggatatct
     2401 ttgatgacga taccaccggc agaatatgga acatagccca ttttatgtgg gtcaatcgtt
     2461 acagattctg cttcttcgat tgctttatat gcactgtgta cttcttctaa gatataatct
     2521 ttgttttctg taaagacatt gtatttgtaa tgaacatctt ttaaatcttc aaatggaatg
     2581 aagttgttgt cttcgtctaa gaaaatcgca cggccgtatc cgccataagc agcatctacg
     2641 tgtaagtaga agtaaatacc gtctttttct aatacgcgac gcaatgcaac gattttatcg
     2701 ataccgtcga ttgctccttc ttctgttgat cctacaacac cgactacacc taggattggt
     2761 gttttttcag ctgctagacc acgaacgatt ttttcaagtt cgttgatgtc catgcgatag
     2821 ttgtggtcaa ctggcactgg aatcacttgg tctaaaccga taccgatgat gtcggcagct
     2881 tttagccatg aatagtgttt agtttgtgga accaaccatt ttcctaattt ttctaaatgt
     2941 tttccgctac gtgctgagtg agctttgatt tcgtcgattt tttctgggac gctgtctaac
     3001 agattcatga tttcttctgt tgacaagttc attaattccc aatcgctttt tccagcaact
     3061 agttcaggtg tcacttcttt cattgcaagc ggcaatgatt tgatgttgcg ggcataccaa
     3121 agtccttcta agtttgctaa agaaccatca gcaacgatgt ggccccagcc atctttatag
     3181 ctcattaatt ttgcaaattc cattcctact tcttcttcca tttggcttgt tgcaggagaa
     3241 gattcatagg caacgttatt accattccat agcatagcaa aattgtacgc tagtaaagat
     3301 ggcatcaatg tttcagagtt catatgaccc cagtaacgtc cggcattatg ccaaggaacg
     3361 gaatgggtac gcatccgcgc tgaaatttct gatagaacat cctttgtttt attcacagtg
     3421 tgttcaaaac tagcactgct tttttcttct ggcgtaataa taggcatgtc ttgaggcatg
     3481 tagttttgac gccagcctaa atgttcatcc accaattcat tcaacaaagc tttatagatt
     3541 tggccgttct cagctttgtc cccaatgaat agggcattta ggtttagatc tttcgacaat
     3601 gattcactca tagtgaaacc ctcctaaaaa aatatttaaa ttttgtcgag ccctacatta
     3661 cacctgttct tctattctgt aaactaagtt ttggcctgat ttttaatcat attttaatat
     3721 gtatcaatta tccgaattgt tcacactttt gaaataatta aaaaaaacga gggaatttac
     3781 aaatgtaaac tccctcgcaa agattgtatt aacgacaacc agcgttctat tttaggatgg
     3841 gtttcaaaat tggaatgttg taatagtatt tccctttttc aaggtaaaaa cttactaaat
     3901 tctaatcaat tactttggcc aaaaagtaat ttttcttacc ttttcgaata accacaaact
     3961 taccatcgaa ttcatcggat ggatttatga caaaatttaa atcggtaacg cggtcaccgt
     4021 taatacttat agctccgttt gaaacatctt cacgtgcttg acgtttagat ggttcaattt
     4081 ttgtggaaac aagcagttcc acgatatttt caggtgtgct tgaaatttca acgttcggca
     4141 ttttaccgaa tccttgcgcg atttcttccg catttagttc tttaatattt ccagagaaca
     4201 atgcttgcgt tattttttgc gcttctttca agtcttcttc actatgcaca aatcttgtaa
     4261 cttcttctgc caaacggcgt tgtgcttcac gtttctcagg ttctgtctct acttttttcg
     4321 ctaagtcttc gatttcttct tgagacaaga aagtaaagaa tttcaagtat ttcactacat
     4381 cgcgatcatc ttgattcaac cagaattggt agaactcaaa tggtgaagtt ttcttcggat
     4441 caagccaaac ggcaccgcct gcagtttttc cgaatttcgt tccgtcagcc ttcagcatca
     4501 atgggatcgt taaaccgaac gcttctgctt ctggtccttc taattttcgg attaggtcta
     4561 atccagctgt gatatttccc cattggtctg ctccaccgat ttgcaattgc acatcgtatg
     4621 ttttatgcag atgcaaaaag tcgatagatt gcaggatttg gtaagtaaac tctgtaaatg
     4681 agattcctac ttccaaacgg ctggcaacga tatcttttgc taacatcgtg ttgatgttga
     4741 agtttttacc gtagtctctc aaaaattcaa gtaaagagat ttttgacaac cagtcgtagt
     4801 tgttcacaaa tgtgatattt gcatctttac caaacaattt tctcatttga ttggaaagtg
     4861 cgtccacgtt atgttgcact tgttccatcg tttgcaacac acgttctgtt ttgcggccgc
     4921 ttgggtcgcc gatcgttcct gttccgccgc caatcagaat atatggatga tggcctgcca
     4981 attggaatct tttcatcatc ataaatggaa tcaaatgtcc gatatgcatc gaatcaccag
     5041 ttggatcaac gccgcaataa agtgaaatgc tcttttcttc aacgagctcg cgaagtcttt
     5101 cttcgtttgt ttgctgatta atggcgtcgc gccaagttaa ttcatcaata atattcattt
     5161 tactgacctc cgtgtagttt ttttatgaaa gcaggaacct gctagcatgt gtaattaatt
     5221 atttcttcag gataggatag gaaataaaaa aagtcccttg gcatataagc caagggacga
     5281 aatctcgcgg taccacccaa tttgtatgtc tagatatcca acatacctct cgaacattta
     5341 acgctgtcgc gtggcaatca ctgccaaaga ctcctgaaat gtaattcgct ttaaagcatg
     5401 tactggtttg cagcgaccac cagctttctg aaacattggc tttaacaact acttcgtttc
     5461 gatcttcgtc ttgttattat taatatgtgt ctatcataga gcgcaacttt ttctttgtca
     5521 acagaaaaag gatatttttt ttaaattcct cattttttct tttttgaatc cgctctaatt
     5581 ccgaacattt tattttcaat tattgttaaa agaaataact ttttctgtat tttttctgca
     5641 atttatcgag aagtcacttt actttgcctc ttattctttc ttcgttacaa taaggaatgg
     5701 gacaagtaaa aaaatgaaaa agcaagggac gaggtatatg gaaaaaaagc aaaaaattat
     5761 tttaggagcc acttctgctt taactatcgt tattttaatt ctaagtttgt tttttgtcat
     5821 ccgatcatct acaaaaaaag aaccaatcat tcctgaaaaa aaaataacag aaaaagcaaa
     5881 agaaccgaca gatgataagc aacaactagt tactcaagca aaaaatctgg ctcaaagcta
     5941 cgattatgac caagcgattg cgttattgga aaaagatagt aagaacggat ctactgaaac
     6001 acaacagctt cttcaaacac taaaaaagga gaaagaacaa ctgatcgact ggtctgatcc
     6061 tactcagatc tctcatgtct ttttccacag cttgatcgtg gacccgcaaa aagccttcca
     6121 ctctcaacag gcacaaggat acaaagatta tatggtgact gttgaagaat tcaaccgttc
     6181 gatcgaacaa ctttatcaaa atgattttgt tttagttaat ttgaatgatt tgatccaaaa
     6241 agacgaacaa ggaaatcttt cctttaacgg gcttgcgcta cctgaaggaa aaaaaccatt
     6301 ggttctttca caagatgatg tcagctatta tgaatatatg gataattccg gttttcctag
     6361 ccgattggtc gtatcaaata acaatgaaat caaaaatgtc tataaagaga aagataaaga
     6421 agaaatcggt gactttgaca tggttcctct gatcgatgcc tttgtcaaga aacatcctga
     6481 tttttcttat cgaggcgcaa aaggtacctt ggccctgaca ggttacaacg gagttttagg
     6541 ttatcgaaca tcaaaatctc aatatggaga caatgaaaaa acaaaaaaag agattaaaga
     6601 agctaaaaaa gtggcggaac agttgaagaa agacggctgg agctttgctt cccatacatg
     6661 gggtcacttg aatatgactc aagcttcact agaagatgta aaaaaagaca atgaattgtg
     6721 gcagcaagaa gttgcaccta tcctaggaaa aacaaatatt ctgatttatc catttggtgc
     6781 agacatcagc gactggcagc cttattcagc agaaaatcaa aaatttgctt acttgaagag
     6841 tcaaggtttc gatattttct gtaatgtcga tgcttctaca ccagcttggg gacaattagg
     6901 tacggatttc tatcgaaatg ctcggatcaa tatcgatggc attcgttttc aatctgattt
     6961 agacggaaaa aatcctattc ttgatccatt catcaatgtc catgatgtct atgacaaaga
     7021 agcacgcgaa tctgcttgat tttacgtcat ttatgaacca aaaaagccga actgacattt
     7081 tatcgtcagt ttcggctttt ttatgcttta tttcttcttc ggtgcgattc ccttgatcag
     7141 gacttctgtc cattctgctg tatatggaag cagttttgcg tatatctccg gcttagaaat
     7201 tccttctacc attgcttgaa aatagaggat caagaactca tccgaatatt tcaaatccac
     7261 ttttccttct ttccgccctc gatggaaaag atcaagcatg atactgaaac tttcttgcgt
     7321 atacgcatcc atcgcgtcag aaaattcttt tttttctttt tttgtatagt atgtcatcaa
     7381 atcgatataa aattgtttgt tcactcgatt gagataacgg attttgtttt cactcatggc
     7441 aatcagtgtt tcttcaaatg gaagattttc cgcaatcaac gctttcgctt cttgccctaa
     7501 atcattcata aatgcaaaaa atacttcata aatcagccct tccttgctgc caaaatattt
     7561 aaaaatcgtc gctttactta cctgagcgtt ctcagctacc ttatccattg tcactccagc
     7621 ggttcctatg tctgtgttca tcaagtcaaa agctgcttgt aaaatctctt tctttttctc
     7681 ttgtgctctc ttttcaaaac cgttcatttg tagagcctcc cgtaatttta aacttttata
     7741 atatatatag ttcaaattta ttctgaggtt tattataact atctattgag aaagtatcaa
     7801 gctagcaatt ccttgtttat gaattcattg acagaaattt ataaaaagaa tattatgtac
     7861 taaaataata aaaaaaagtt ttataaaaag gtataaaacc tttttattaa actatttaat
     7921 cttgtttagt atatattttt agaaaaagga gtggggtttt tatggcagaa atcgtcaaag
     7981 tcacacattt gaaaaagagc tttggtcgtt tcgaagcttt aaaagatgtc tctttcaccg
     8041 tacattcagg tgaagtcgtt ggatttatcg gaccaaatgg ttctggaaaa tccacgacga
     8101 ttcggacact tttagggatt ataaaaaaag acggcggaac ggcaacgatt tttgggcaag
     8161 atgtatggga agatagttta tctatccatg aacgtctttc ttatgttcca ggcgatatct
     8221 ctttgtgggg aaatttgact ggaggagcga tcatcgatct cttcatgaag cttcatggaa
     8281 aagggagtgc tcaaaaaaaa gatgaactga ttcaacgttt ctctcttgat cctaagaaaa
     8341 aagcaaaaaa ctattcaaaa ggaaatcgcc aaaaagtggg cttgattgct gctttggctg
     8401 ttgattcgga tctctattta tttgatgagc ctacttctgg tttagatcct ttgatggaaa
     8461 cgattttcca agaagaagtt gaaaaattga aagaacaggg caaatccatc ctactttctt
     8521 ctcatattct cagtgaagtc gagcgactag cggataaagt cgtgatcata cgcgaaggaa
     8581 cactcgatga agaaggaaca ctcgatgaat tgcgtcattt gactcgttcg accatcacta
     8641 tagaaacaga agcagagaat agtcacttag cacaattgaa cggtgtccat gactttgtgc
     8701 aaaaaggtca cctcgctcaa tttgctgctg ataacgaagc tttcgatgtg attttagctg
     8761 aagcgtccaa attaggtgtg aaaaaatttg aatctattcc accgactctt gaggatttat
     8821 tcatgagaca ttatgaagga tgaggaggaa gcgaaatgac tgataaattt tcacgctggt
     8881 ccaccctttt ttctcaaaac cttagccgtg actggaaaaa gatcctgata tggctagtcg
     8941 gtgtcactgc tttttctggt ggttttgtcc ctgcgtttga agaattgact tccggacaag
     9001 gattagctgg attatacgaa accttgcaaa acccggcaat gattgcaatg gtcggaccaa
     9061 ctccagcttc gaatgctgct gagtatactt taggagcgat gtatgcaaat gaaatgttgc
     9121 ttttttgcag tttgtttgct gctgtgatct ctgttttaca cgtggtgagc caaacgagaa
     9181 aaaaagaaga acttggtctg attgaactta ttcgttcctt tcgagtcgga cgtcaagcaa
     9241 actctttagc tgtcatcgct gaaagtattc tgatcaattt gcttttagca atatcgatca
     9301 gctgtacgat gatttttttc caagcggatt cgatcactgc agaaggtgct tggctttttg
     9361 ggctatctgt aggtagtatg gggattttgg ggagtgccgt tgcactgttt gctgcacaac
     9421 tgatgccaag ttcagccagt tcgaatggtc tgtctttagc gtttttaggt ggactttacc
     9481 ttctacgagc aataacagat gtagctgatt cctccctttc gatgtggaat cctttaggct
     9541 ggtcttattt gacctatcca tttacaacta acaactggat tcctttgctt tatttgtttt
     9601 tgttcagtct aatcttgata atcagttcat ttgttttaga ggaacatcga gatttgaaca
     9661 ccggctatat ccccgaacgt gaaggaaaac cgtatgctaa acgttctctt ttatccttgc
     9721 gtggtttatt attctatcta aataaaggga tgacaatcag ttggcttatc acttttggtt
     9781 tgatgggggc ggcatacggc tctatctacg ggaatatgca acagttttta gaaagtaacg
     9841 acttaatgaa acagatgttt atccaatctg gcgtctcaat tgaaaaaaac tttacaagca
     9901 cgatcatggt agtcttgatt tgtctagctg ctattttacc aattgctagc atcaatcgtt
     9961 tatttacaga agaaacccac ggacgtatga atcagctgtt cgcaacaaaa atttctagga
    10021 accaacttta ttggaccaat atgttactag ctattctatt tgctatattg gcaatcctga
    10081 ttagttctgg tgcactaggg ctttctgctt tggcttcgat gaaggatgcg aaagacatgg
    10141 atctattgat gtttcttaaa gccgggttca atttcctgcc tgccgtttta gtgtttatcg
    10201 gaattagtgg ctttctattc ggatggcttc ctcgaatcgg taaacttgct tatatctact
    10261 tagcttactc ctttgcactc aattactttg gcggaatttt ggatttacca gaatggtttt
    10321 ccaaaacagc tgtccctagc tgggttccac ggatgccaaa cgattctttt gatctttccg
    10381 tgttccttac gttatcatgt atcagccttg cactgttcgt ccttggttct attggttata
    10441 ggcgaagaga cttactagaa ggataataaa aaagcatgta caatttcatg ctagcctcca
    10501 aatctgggtc aaaaatccaa catttggagg tcattttttt atttacaagt cttctaactg
    10561 ctctttatca atgatccaga cttctcgatt ctttcttttt acataaccat tctcctctaa
    10621 taatttaaat tttctagata aagtttcggg ggtcgtaccg ataaatgcag caagttcttt
    10681 cattttcatt ggcaggaaaa agtgatcctt ccctgtcgct ttagctaagt caagcagata
    10741 gacagcgact cgttcttcta ctttttccat catcaaaaaa gttgtctgct gctgtacttt
    10801 tgttaatttc tcaacgttga ttgctaaaag tttcagacta agggcgggat aatgcagtaa
    10861 gagttccgag aaatcttttt gtctcaatat gcaaatttcc gttttttcta gtgcttcgcc
    10921 aaataaagac tcatttggaa cgcctagcaa ctggctctct ccctcatatc cgcccggctc
    10981 tattactcgt aaaagctgtt cctttccgct agcagataat tgatacactt tcatactgcc
    11041 ggaggccacg atcactaatt gaggttctcc attcggcgca agaatctgtt ctcctttttc
    11101 cacatagtga tgtttgacaa gtgcgtgtac tttttcttga tcttgctgta ctaagtgatt
    11161 gaacaaagga acaaatgaaa cacataaatg atcatgactc ataatctctc ctccttctaa
    11221 acagctattt ctaataaaga aacataactt cccttattcc aactgataat tttcttttat
    11281 catagcataa acgtcaagcg aaccagatac cagcaaatag agtggatttc tttttgtccc
    11341 ttgctttatt ttccttcttt tgagacctta agtaattgat tcctatcaat tttttaaata
    11401 tttacttttt
//
LOCUS       DADGKS010000081        11407 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.082, whole genome shotgun sequence.
ACCESSION   DADGKS010000081 DADGKS010000000
VERSION     DADGKS010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11407
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.082"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(56..280)
                     /locus_tag="JXV47_002397"
     CDS             complement(56..280)
                     /locus_tag="JXV47_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HAX1488411.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(478..2058)
                     /locus_tag="JXV47_002398"
     CDS             complement(478..2058)
                     /locus_tag="JXV47_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HAX1488412.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(2459..3835)
                     /locus_tag="JXV47_002399"
     CDS             complement(2459..3835)
                     /locus_tag="JXV47_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAX1488413.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(3963..5081)
                     /locus_tag="JXV47_002400"
     CDS             complement(3963..5081)
                     /locus_tag="JXV47_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAX1488414.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            5223..5657
                     /locus_tag="JXV47_002401"
     CDS             5223..5657
                     /locus_tag="JXV47_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1488415.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(5735..6268)
                     /locus_tag="JXV47_002402"
     CDS             complement(5735..6268)
                     /locus_tag="JXV47_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HAX1488416.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(6362..7540)
                     /gene="mutY"
                     /locus_tag="JXV47_002403"
     CDS             complement(6362..7540)
                     /gene="mutY"
                     /locus_tag="JXV47_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HAX1488417.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(7533..8330)
                     /gene="recX"
                     /locus_tag="JXV47_002404"
     CDS             complement(7533..8330)
                     /gene="recX"
                     /locus_tag="JXV47_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HAX1488418.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            8437..9819
                     /gene="rlmD"
                     /locus_tag="JXV47_002405"
     CDS             8437..9819
                     /gene="rlmD"
                     /locus_tag="JXV47_002405"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAX1488419.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(9993..10571)
                     /locus_tag="JXV47_002406"
     CDS             complement(9993..10571)
                     /locus_tag="JXV47_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin-binding protein"
                     /protein_id="HAX1488420.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            10893..11363
                     /locus_tag="JXV47_002407"
     CDS             10893..11363
                     /locus_tag="JXV47_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HAX1488421.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
BASE COUNT         3356 a         2289 c         1946 g         3816 t
ORIGIN      
        1 gaattccagc ttatttcttg gagttaaacg cttctgtctc agcctctttt tctttctagc
       61 tttttgattt ttctcttttc ttttgtactt ttctcttttc attttcagtt ctacgcgtgt
      121 ctttattttt aactttttcc tctttatgga tgattgatcg tactttttgt gcaatttgct
      181 cgtttttgtc ccagtctttt acatctaata atcgacataa tcgtaacatc tcttcttttt
      241 tctgtttttt tctttcacgt ctttgccatt ctgtttccat gtgtcacact ctcctttctt
      301 taatcatatg tacgcaaaat aatttttata tttttttgat tagacatttc tatgatttta
      361 atatagtaaa aagagccgtc acggaaaatc cgtcacggct ctaaacaaaa tatgagaggc
      421 tgtttttgtt tggctattct tattacttga tgcagggcag cttgtgtcaa gacttcttta
      481 catcaaactt tttaatttta cattgggata tttatccgca aaccagcgtt ctgcaaattg
      541 gttctcgaat aagaacaacg gttggtcgaa acggtcacga gccaagatat tgcgacttga
      601 actcatcttc tcatccaaat cttctggatc gatccagcga gcgattttgt gtcccattgg
      661 agacatgatt acttcggcgt tatactcatt taacatacga tattggaata cttcgaattg
      721 tagctgacca acagctccaa tgatatattc ttccgttaga tatgttttat aaagctgaat
      781 cgctccttct tgaactaatt gatagattcc tttgtggaag gatttttgtt tcatgacatt
      841 ttttgcagtc actttcataa acagctctgg agtaaatgaa gggagttctt cataagcaac
      901 ttttagtttt ccttcgaaca atgtatcccc aatctgataa ttgcctgtat catatacacc
      961 gatgatatcg cctgctactg ctttttcgac gttttctctc gaatctgcca taaattgtgt
     1021 gacattgctt aatttcagtt ttttatttgt acgttccaac cagacatcca ttcctcgttc
     1081 gaatgttcca gaacagattc ggacaaaagc gattcggtca cgatgggctg gattcatatt
     1141 tgcttggatc ttgaatacga aacctgaaaa ttcttcctca taaggactta ccatctgatc
     1201 atcttgtgtt ttgtgtccat aaggagctgg tgccaattca acgaaagtct ctaaaaaagt
     1261 ctgtacaccg aagttagtca atgcagaacc aaaaaatact ggtgtctgat cgccacgagc
     1321 aattttttct tgattaaatg catctccagc ctctttgatt agttctactt cttctaagac
     1381 ttgttcatat aaggaatttt cagttagagg atgattttcg ggaagcagtc catcttcatc
     1441 caattctact aatcgttcat cctgataatt ttccggacga taaaactcta cacgattatg
     1501 gtagatatca taaagacctt ctagcccttt acccataccg attggccaat tcatcggata
     1561 agattcgata tctaatagct cttctaattc ttctaacaat tccaatggtt cacgaccatc
     1621 acgatctagt ttgttgataa aagtaaatat cgggatgcca cgttttttta caacttggaa
     1681 taatttcttt gtctgtgctt cgatcccttt tgcactatcg attaccatga ccgcactatc
     1741 cacggccatc aaagtacgat aagtatcttc agaaaaatct tcatgtcctg gtgtatccaa
     1801 gatatttact cgtttccctt gataatcaaa ctgcataaca gaactagtaa cagaaatccc
     1861 acgttgtttc tcgatttcca tccagtctga tttggcaaaa ttacctgttt ttttgccttt
     1921 tacggtcccg gcttgacgga tagccccacc aaacaatagt aattgttctg taatcgttgt
     1981 tttcccagca tccggatggg aaatgatcgc aaaagttctg cgattgtcca cttgttgctt
     2041 taattttgga ttattcataa cctaactcca tttcttccat tcaattattt atattttctc
     2101 taggcacaga ttgtccgatc tcttaaagaa agacaatttc atatagggct gtgacaaaag
     2161 ccgtgtagca gtctcttttt ccgagtaaac ggcgttctag agacagccta tcagcaataa
     2221 gcccacccaa gccaaaaata cgaaaagctg tttttgcttg gctgctctta ttacttaatg
     2281 caggatagct ttttcacaac ctttgtcaac tactacaact gaatcagtat agcatggatt
     2341 cagcgaatga aaaagccacc aaaccataag agtcaaatat ttttttgtca gctgactaaa
     2401 agaaaagacg tgttgcttgt ttattcaagc aacacgtctt tcataaccaa gtttccaatt
     2461 atcttcttgg ctcgtcatct tcgaattctt ttctgaagta tcttcgttct tcttcaggtt
     2521 ccgcttctgt ttcttccgga tcatgaaaaa tgacacggat tttaaggatt cgagaacctt
     2581 ccatttcttc agaaaccagc gtaatattat cgacatcaaa cgataacttt tcgccttcat
     2641 ccggaatcat gcctaatgct gtaatcaaat aaccagccat cgtatctaca tcactcatat
     2701 gcagatcact gtcaaaagct tcattgaact catcaatcag catacgtcct tggatgatat
     2761 attcgtgttc atcgattttt tcataaagat tctcaacttc atctgattca tcatcgattt
     2821 ctccgacgat ttcttctaaa aggtcttcta gtgttgctaa cccaacgacg ccgccatatt
     2881 catctaataa aatagccatc tgattctgcg tctttttcat ttcatataac agatcatcaa
     2941 taaagaccgt ttcaggaacg aataaaggct cctgcatgat tttcttgata tctaaattat
     3001 caaagccgaa tttatgggca gcttttagta aattctttgt atgaaggatt ccgactactt
     3061 tatctttgtc ttcgttataa acagggattc ttgaatagtt ttcggataaa acttcattca
     3121 cattttcttc cacagtgtcg ttgatatcaa tcataaatgc atccgttcgt gggaccatga
     3181 cttctcgggc aactttcgta tcaagagaaa aaaccccttg gagcatttct aattcttcat
     3241 tattcaatac gccttcgttt tcaagcatat aacgcatttc atctctggtc atttttgaat
     3301 cttcatcatc aaaagtcatc ggcgtgatac gcgccaataa acttgtggaa gcagaaagca
     3361 gccagacgaa gggcttagct actacaccaa tcaagcgtat cagccctgaa gtgaactttg
     3421 cgacttcttc tgatttattt aaagcaatac gtttagggta caattctcca aaaacaatcg
     3481 atacataggt caaaatagcc agcacaatga tatttgcaat attttttgcc gctgtgccgc
     3541 cacctaatac cggagctaac cgttccgata aagtattagc tagtgaagca ccagacaaaa
     3601 tgttgaccaa agtgattcct acttggattg tcgataggaa attatttgga ttctgcaata
     3661 tttttaaaag cttttgagat ttcacatctc cttcatcagc tttttgctcg attcgattct
     3721 tattgatcga aacaacagca atttcggaag ctgctaaaaa agcattgatc aatgtcaaaa
     3781 cgatcaataa taaaatctgc gctaacagcg actgactctc agggtcagca ttcataatcg
     3841 cattctctcc ttataaaatt aatttttagt ttacgataga aaaaaacgtg gcactatagc
     3901 cacgttaaaa tggtatcaca aagcaatttt ctttgcaata aaaacaagtg tactaaaact
     3961 acctacgagg tcgtagcaat tttcttcttg ttttcatttt gcttgtcttc tttgacgatt
     4021 ttgattatat aggaaatgat cgtcttgcag attgcgtaaa aaggaacacc taagaagata
     4081 ccaagcaatc cggcaatatt tccagctact agaagaacga taatgatcgt taatggatgg
     4141 attttcagtg atttcccaat tacattagga taaatgatat tcccatccaa ctgttggacg
     4201 attagcacaa ccacacaaca aagtaatgct tttaccggat cattgaagac tgttactaga
     4261 aatgcaggtg ctagtcctag ataaggtcct aaatatggaa ttaggtttgt caatcccgca
     4321 atgaccccaa ataagaaagc ataatccaca ccaattacca tatatcctaa aaatgtgaag
     4381 gtaccaacga ataaacattc gattgcttgt ccgctaatgt aattagccaa tgttttattc
     4441 agttgcccca ataactccac aatttggttt cttctttttt ctgggaaaaa ctgttggatg
     4501 tttggcacta gtttttctcc gtctttcaac atatagaaca agatgaatgg tgctgtaatg
     4561 attactacgg ttgccgaagc gatcgttcca acgatcgaac ctaaactatt ggatactcca
     4621 ctaaggaatt gctgaatgat tgtcccgtaa gaaatgtcta attgctcaaa atatttattg
     4681 atatctactt ccttgaacaa aggcaattcg gctacctctt ttaaccagct ttctacctgt
     4741 ttgatgaaat caggcatatt agatgccaat gaggaaattt gctgtactag acttgggatg
     4801 acactaagta aaatccaaat aattgctgca actaaaagga gcagcacaat tgcgacagcc
     4861 catattcttt tgatttttgc tttcatcaac agcttgacaa taggattcaa taaatagtaa
     4921 agaaagcctg caatcagtac aggtgcaaat aacgtggaaa aaaatgtccc gatcggttcg
     4981 aaaataaagt ttatttctga tgaaatcatg atcaatgcag ctatgatcaa taattcaagc
     5041 gaccaaaaca ttagtttaga ctgtctaagt ttttcaaaca atagatttcc tcctttcttt
     5101 cttactagta tatattatat tcgttaaaaa ttcttttatt ctttttttat ttttgaaaac
     5161 ttgccatact ttttatttgt tttattttcc agtatactat acgaaaggaa ggtggctaga
     5221 ccatgaaagt tgtacaaaca aaagatacaa tgagcaatat ttacttagat gctgtacgga
     5281 tcaggcatca agtttttgta gtcgaacagg gtgtgccttt gtctcgagaa atagacaaag
     5341 atgaagccca ttgtatccac ttcgtcctgt actcagataa aaaagaaccg caaggaactg
     5401 tacgtctttt gcctttagaa aacggaaaaa tgaaattaca gcggatggcg attctttctg
     5461 aatacagaca ccaagggtta ggaaaaatat tgattgaaga agcagaaaac tttgctaaga
     5521 atcaaggcta taatacgatt ttattagggg cacagtccac agctgaaact ttttacgaaa
     5581 aactaggata tacagcttac ggcgatcctt ttgaagatgc tggcatgcct catatttata
     5641 tgaaaaagac tttataaaaa tttatttcga aaaaagcaaa aaacagcaag cttttgagaa
     5701 aaatctctca ctggcttact gttctttttt gtgtttactt acgcgacaat tgcttgtaac
     5761 ggttatacca aatatcaata tagccttccg agaacgggcc atctccatta ttgatccagt
     5821 caaccagaat cttcacattt tcttttagga tgaagtcaat atcgttcggg taattcatca
     5881 ttttgctgtg catctcatat tcatcgacat ccaatagtcg tttctcgccg tcaggaaata
     5941 ccttgatatc caagtcatag tcgatatatt tcaaggcctc atcgtccagc aaaaaaggtg
     6001 aagctagatt acaataatag gaaaccccct tttctctgat cattgctatt acattgaacc
     6061 agtatttttt atgaaaataa acaatcgctg gttcgcgcgt tacccatcgg cgtccatcag
     6121 attcagtgac taatgtgtga tcattcacgc cgatcataga gtgttcgctt gtttttaata
     6181 ccatggtatc tcgccacgtt cgatgcaatt tgccgtcgtg cttgtaactt tggatcgtca
     6241 caaactctcc ttcttttgga actcccatag caacccttcc ttaagcagca ttttgtgctt
     6301 tgtgtttggg tgttcattac accgacatca taattattat atcaataaaa atgagctttg
     6361 cctagaaagg attcctattg tttcgatttt tctctaactg atctaccagt ttcatttgga
     6421 ccttaggaaa aacgaccgaa tcaaatgcat caggcttcaa ccacttcgaa gttttgttct
     6481 cggtaaattc ttgttctgct ccctcggttg cccgtccgta aaaaaggaga acatgccatt
     6541 tcagatgact aaaaatatga gtaacttctc ctaaatgtcg tgtctgccaa acaaagagtt
     6601 cctgcttttc aaatgggaga ttttgctctt cttctgctac taggtcatca aacagatcga
     6661 tttctggctt tgtttcccat tcttttttca atcgctcata ctcctcttgt gtcacttcca
     6721 tcattggaaa tgtccacata ttcgccagca atttttggct atctctttct tcaaaataat
     6781 acgctccaga atgattttga agagctgcac tgatataata aacgtctttt ggctttgctt
     6841 tttttgtttt tacaggaaaa ctcgtttgga ttcctcgttt gttagctaaa caaaaggctt
     6901 ggatcggaca agtctcacac tttggagaag ttggtgtaca gatagctgaa cctagatcca
     6961 tcattgcttg gttgaattca cctggatgct tttcatcaat gattttccgc atcgcttcat
     7021 caaagatttt cctgctagaa gcttttgcga tgtctgcttc aatgcaaaac aatctgctga
     7081 ctactcgcat cacgttgccg tcaactgcag gttctggaag tccaaatgcg atacttgcaa
     7141 tcgcgcctgt cgtatatggt cctattccct tcaatgagct aatttcttca ggcgtttgcg
     7201 gcatttcccc atcaaattct gacatgatct gtttagcagc agcttggatg ttccgggctc
     7261 ttgagtaata accaaggccc tcccatgctt ttaaaagctt ttcttctgga gcatttgcta
     7321 gctcttcaat tgtaggaaac cattccatga aacgataaaa ataatcgatc actgtgtcta
     7381 ctctggtttg ctgaagcatg atctcagaga tccagatacg ataaggatca cgattatagc
     7441 gccaaggcag gtttcttttt tcttgttcat accattgaat gaactgatct tgaaattctt
     7501 ttgtttcttt atctgtccat ttttcccatt ctttattcac tttcctcttc cttttccgta
     7561 atgaatcgct ggatcatatc caaatcaaat cctttttgat ataagctttg ctttactttt
     7621 agatttcttt ttttaggttc aaaccttaaa tttcttcgcc atagtttatc tccttgtttg
     7681 actaaataat catattctat ttcttgatct gcttcttgcg gaagatcagc tatcgcttgt
     7741 tggatcactt cttgagaaaa gcctttcgtc atcaatgttt gttggatttt tctcaataat
     7801 tctttttggc tttttccgtg attttttcca aacgcttttt cggctgtctg atgtgcattt
     7861 tgaacttggt cttcaaatgt atattggctg agcgcttgtt caatgatttc aggtttcaaa
     7921 cctttttgct gcatctgctg cgctaatttc tttggtcctt tgtcacttaa gcgcatattc
     7981 gtgcgcacat aactttcccc atagaccaaa tcatcgacaa ggtccaattc ttttaagcgg
     8041 gctacgattt tatttcgatc ttcttgaagg atttcctttt cttttaagta tgttcggatt
     8101 tctttttccg atcgcaactg ataacttaag taattcattg ctaggtgaaa accgaaatca
     8161 gctccgctac tcttcttgat ctcttggata gtttcttcgt ctaattcccg tccttttaat
     8221 aatcgatagc gtactaatac atcttcagat acttgtaaag cttctccttc agataaatct
     8281 acgcgataga aagggccttt gcctttactg attctcgtaa cggttaacat aaacatcctc
     8341 ctcgaacata tattctctat cataccacag aaaatccccg taatcaggta ttatatgtta
     8401 gaataaacca cagaaaaaag aaaaagggag atacttatgg cagaaacaat tgtcaaaact
     8461 ggacaaacgg ttcctttgaa aatcaagcgt ttaggcataa atggtgaagg aatcggttat
     8521 ttcaaacggt tgatcatatt tgttccatat gcactaccaa aagaagaagt actagtgaaa
     8581 atcacgaaag caactcctcg ctatgcagaa ggagaattaa taaaagtcaa aaaaacaagc
     8641 aaagatcgcg tagtggcacc atgtcctgtt tactatgaat gcggtggctg tcaattacaa
     8701 cacttagctt atcaagctca attggatttt aaaaaggatc tgcttttgca agcattggaa
     8761 aaattcaaac cagcaggctt tcgatcttat caacttttgc cgacgatcgg gatggatgag
     8821 ccttggcatt atagaaacaa agcacaattt cagttacgaa aaaataagca gactcaaaaa
     8881 attgaagctg gtttatacga agcaaactct catcagttag tccctataac agactgcttg
     8941 gttcaagaac ctcgaacaca aaaagtaatg aatactgttg ttcaactatt gaataaattt
     9001 gatgcaccca tctatgatga acggacaaac agtggaatct tccgcacaat catggttaga
     9061 atcggtgtta aaactgggga gttacaagtt gtttttatta ctcgcagtaa aaaattcccg
     9121 caaaaaaacg caatgatccg tgagatcaat gaacgactgc ccgaagttgt ttcaatcatg
     9181 caaaatgtcc aggcacaaaa aacgtctctc gtgatggggg atgaaacgat ccacttatgg
     9241 ggaaaagaag ccattgaaga acaaatcaat gaagtgactt tcgatctttc tcctcgtgcc
     9301 ttctttcaac tcaatcctca gcagaccgaa ttgctttatg gcgaaggaat caaagcatta
     9361 gatgtccagc ctaatgaaac gatcgtggat gcttattgcg gagttgggac gatcggctta
     9421 agtgtagcaa aacaagccaa agaagtacgg ggaatggata ccgttcctca agcaatcgct
     9481 gatgcaaaaa aaaatgcgga aagattagga tatcacaaca ctcgatatga agtcgggaca
     9541 gcagagcaag ttctgcctaa atggttgaat gaaggttttc agcctgatgg tatcatcgta
     9601 gatccaccac gtacgggttt ggataacgca ttgatccaat cattattgaa ataccctcca
     9661 aaaaaacttg tttatatctc ctgtaatgtt tctacacttg ccagagatct ggttaattta
     9721 agtaaaaagt tcaagattga atatttacag tccgtcgaca tgtttcctca gactgcacgt
     9781 tgtgaagttg tcgtgaagat gacgagactc gctgactaaa tgaaagaggt tgtgaaaaag
     9841 tctgccctgt atcaagtaat aagaacagcc aaacaaaaat agctcttcat gttttatgaa
     9901 tactgtactt gtgaccgaag agttaacagg aggacactat ttatttaaaa aaagggttgt
     9961 gacatagttt ttgtcacagc cctttttgat tattattgga tattcacgtc tatcacttga
    10021 taaaatgcat ttgtcgtatc gctgatattc catactgcta aaatcacatt atatcctttt
    10081 cgatcctgcg gaagtgtgat cgtttggttg actgtttttg gtggaacagt tgctttgtcg
    10141 tctatttttg tgatcaattc aaaatcacta aatttcaaag gttgattagg attccaagtt
    10201 ggtttggtaa tgtagtaatc ccaagtactt gtccgatgtt gtgctgttaa attccaagta
    10261 atatttaatg ttcctggatt aaccatgttt ttatgccatc tgttagatgt ctgttcatct
    10321 aaaggctcaa agccgctgac tcctgcacta gcaatttttc catcaatgaa tgtatttttg
    10381 gtagcttcga tactttgcgg ttcccattgt gctcttccga cattttgatt taagtttcct
    10441 gctgctgatg ttcctaggta tgcacggctt cctggagaag taatataacc atgcgcaaaa
    10501 cctggaatgc taaaaccgaa caaccctaaa ctaactaacc caataaacaa taacgtacta
    10561 atctttttca tgtagaaacc tccttcattt gataaccaca ttgtaaacgc tttattgtat
    10621 taacacaaac attatgcttt tataatttta tgttgaagta aaaaaggtga aaaaagtaag
    10681 atgcagatta taacagaagt agacgagaaa agtacaaata gaaaacatga gaatcaaatc
    10741 atatgatctt tttcaaaaac atcattcata taaacaaatg ttcaactttt taataacaac
    10801 aattatcaat ttttttctta cttcacaaac taaatacagg tcttgctgtg agccttcatg
    10861 gtaaactaat attatagaaa ggagttagta aaatgaagat gataaaagat attcgttttt
    10921 gggtttgtgt tataggaatt gtcatattag gctttttatc agggttgctt agcggaaatc
    10981 ccggaaaata ttactattct ttgcaacttc caccatttgc accacctagc tggatatttg
    11041 ggccgatgtg gaccttactg tatatattga tgggtatttc tctttatttg ttacttaatc
    11101 acaacaacaa aaaacagcga aacaatcttg tcggtctttt tgtgattcag ttcattttta
    11161 attttatatg gtctgctcta ttttttaatt taagaaatat tttcattgca gcaatcgata
    11221 ttacactttt agttattttc ttgtcagtgc ttatgtatca gttgtggctg catcatcgcc
    11281 tggcaatgtg gctcatgatt ccttattatt tatgggtact attcgcaact ctattgaatt
    11341 attcaattta ttttttaaac taagcgctaa aaagagacgt cctgtaattt aacacataga
    11401 aaaagtg
//
LOCUS       DADGKS010000082        11247 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.083, whole genome shotgun sequence.
ACCESSION   DADGKS010000082 DADGKS010000000
VERSION     DADGKS010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11247
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.083"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..2981
                     /gene="fss3"
                     /locus_tag="JXV47_002408"
     CDS             <1..2981
                     /gene="fss3"
                     /locus_tag="JXV47_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HAX1488422.1"
                     /translation="CVEPGVPIYNEFTPGYEKNPLPDMSDKAKLVSVLWKKVGTDADT
                     HIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAIEAKINQAIADYQKKPSFHNSTAKTV
                     LGQSTTVTDTNNLNLSEFDEVVENTANIDYRVNGNQLIISPNANSKESGVLTLKKSAG
                     TGTPVAYKKAGQQTLMAGAIDKPNTYTVKIDVEMEGSLKIKKVDKESGDIIPGTVFHL
                     DFGKTLPAKDVTTDKEGIATLDEIPHGTKVTITEKSVPAPYTIDTTPMTATIKAGETI
                     SVTSKNTREKGQIILDKTGIETGSDLWNDNYSLAGNTFAIRKDSPTGEIVQEMTTDEK
                     GHAETPKEIANALELGTYYVTETKASHGFVNTFKPVKVELNYVNQTVALVTSNVKGQN
                     QEITGETTLTKEDKDTGHETQGKAEFKRAEYTLFTVKDGKAVKWTENFKPELLKGTKA
                     SDETVTLTLDEKNQVAVKHLAINEYYWQETKAPEGYTLDETKYPVSIKKVDDSEKNAV
                     ITRDVAAKEQVIRFGFDFFKFAGSTTGTAETGFNDLTFKVSPLEGTNEITGAEDEATT
                     AYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGFQKITPLEIRSTFKENKEDYTKSDYI
                     FTITEKGQKQPIKTVTVPYGNLTNENFSVSLNRLMLYDLPEEEDSLTSLATWKEGDKE
                     LTTLDSTELVDKLSYNLHEIKEDWYIVAQAIDVDATKAAQEKDKKAKPVAIAETTATL
                     ANKEKTGTWEILHKLTVEQVLDKTIVLFNYVYESKEAYEAGDEPVAKDASLNNQAQTV
                     NCMVERHVSIQTKAHLEEGSQTFTHGDVVDMFDDVSITHDVLDGSKEAFETILYALFP
                     DGTSKEIWKSGKIDYEVNDKEFTKTVLAEKVDTSKYPEGTSFTFKEINYDKDGNINGK
                     HNEDLKEKSQTLTPKKVPTTPSTPEQSEMPTVPSGSQESSPTVKAFPQTGEKTSNVLL
                     FIGFSLIFATAGYYFWNRRN"
     gene            3093..3407
                     /locus_tag="JXV47_002409"
     CDS             3093..3407
                     /locus_tag="JXV47_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAX1488423.1"
                     /translation="MELKFVVPDMVETFGKLTYGGEGEVLSEGYGRNTTIVGRSYHLF
                     SNKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLIAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            3420..3794
                     /locus_tag="JXV47_002410"
     CDS             3420..3794
                     /locus_tag="JXV47_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAX1488424.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQLNQGKPTNQNEGKK"
     gene            3804..4148
                     /locus_tag="JXV47_002411"
     CDS             3804..4148
                     /locus_tag="JXV47_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HAX1488425.1"
                     /translation="MEINVEHILDCLDQFGKGELTEEQLTNALTYDEKMFLIMHQGLL
                     EVGNDAKEDFDVLDWLGEEESFFMVVEVNESLCRQAESVLEEIDVEMPDAIERFLKQL
                     VETKQLPVVVND"
     gene            4217..5233
                     /locus_tag="JXV47_002412"
     CDS             4217..5233
                     /locus_tag="JXV47_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAX1488426.1"
                     /translation="MYKGHRIRAGDQHLIYHFVLGWLIFLFIGWMSVFYLQELRQFDI
                     SKVSFSTSEIGWSMKDVICLLGSLALSGSMMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQGEGFFKDLNSSWTKESISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LENKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIEEIVAENGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIQALLKSDAELFILDPKNADLADLGTIMPHVYSQK
                     EEISECVEDFYERMIARSRSMKEMPNYKTGENYAYLGLPPNFLIFDEYVAYMGANRFP
                     TSIE"
     gene            5827..7701
                     /gene="ltrA"
                     /locus_tag="JXV47_002413"
     CDS             5827..7701
                     /gene="ltrA"
                     /locus_tag="JXV47_002413"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAX1488427.1"
                     /translation="MNVETDEVQGSGKNVGKSVMEVPRLNTKIRYWEYYDLQETFDQL
                     FTQSRNGKKFYQLYELIISENNILLAYRTIKANKGSSTPGTDSFTIDNYKEMNQAEFI
                     HLILSHLENYKPKSIKRVMIPKPNGEKRPLGIPCMIDRMIQQMFKQILEPICEAKFYE
                     HSYGFRPLRSAKHALGRIMYLINISKMHYAVDIDIKGFFDNVNHRLLIKQLWNIGICD
                     KQVLAILSKSLKSPIQGEGIPSKGTIQGGIISPLLSNVVLNDLDHWVSKQWHTFETKY
                     PYTKGYNKFRALRDTNLKQGYIVRYADDFKIMTNDYPTALKWFHAVKLYLKDRLKLDI
                     SNEKSKIVNLRKCKSEFLGFAICVKQKGKKWVCNSRISNKKKDQIKEEIKQRIKDIQK
                     SPTAQNALLFNALVLGVHNYFRYATHINLDLNRMNYVLSFTTYNRLSNCSTRCYPNKA
                     SPTYKKFYSTTMKTYKVAGVYLYPLCDVSTKTIYGFNTEDTPFTPFGRQRLEHKSLQS
                     LVFQELRKLMESKIPNRTVEYLDSRISRYSMKSGKCEITKQFLPAKAVHCHHYLPKSL
                     GGDDKFDNLRIIHKDIHLLIHTTNKMIIDHYVHELKLVPEQIAKINLYRKMCNLQNIQ
                     "
     gene            7827..8183
                     /locus_tag="JXV47_002414"
     CDS             7827..8183
                     /locus_tag="JXV47_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HAX1488428.1"
                     /translation="MILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRV
                     ALGRMSELGYSMMFGEVDKNFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREIS
                     NIVGLTVHTERENNSV"
     gene            8228..9370
                     /gene="dcm"
                     /locus_tag="JXV47_002415"
     CDS             8228..9370
                     /gene="dcm"
                     /locus_tag="JXV47_002415"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HAX1488429.1"
                     /translation="MTFLDLFAGIGGFRLGMEQAGHQCIGFCEIDEFARRSYKAIHDT
                     RKEVEMHDITSVSDEFVRSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     ATLLQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQSRERI
                     FLIGHSRDACTEQVFPIIGSSSTSDQNIRNLVNINPSNRGMGGQVYGSDSVAPTLTGD
                     EGIKIALPVKDGISVAGMLSGNFEQGNRIYEVTGTAPTLSTKQGGTKIMIRKNETEYQ
                     EVKPGDSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKGVKAYDL"
     gene            9360..9649
                     /locus_tag="JXV47_002416"
                     /pseudo
     CDS             9360..9649
                     /locus_tag="JXV47_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395166.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            9905..11089
                     /locus_tag="JXV47_002417"
     CDS             9905..11089
                     /locus_tag="JXV47_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAX1488430.1"
                     /translation="MAQRNLDYRLLKERRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     IASTKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDVRKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYYAIQDLL
                     KGRSIESTTFSIINRYLRFADKVDGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     IV"
     gene            11104..11199
                     /locus_tag="JXV47_002418"
     CDS             11104..11199
                     /locus_tag="JXV47_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HAX1488431.1"
                     /translation="MEIVKDMLLVLGGSMLGVTVMCLMNASAAAD"
BASE COUNT         3772 a         1932 c         2516 g         3027 t
ORIGIN      
        1 tctgtgttga accaggagtc ccgatttaca atgagttcac tcctggatat gagaagaacc
       61 cgttaccaga tatgtccgat aaagccaaat tagtttccgt tttatggaaa aaagtaggta
      121 cagatgcaga tactcatatt gtggcacaga agatgatctg gcaagaagtt aatgggtata
      181 cccttcactc aataaaacga tcagatggta gtgccgtaaa tatcgcagcc attgaggcaa
      241 aaatcaatca agccattgcc gattatcaga agaaaccaag cttccataat agtacggcta
      301 aaacagtatt agggcaatcg actactgtga cggatacgaa taatctgaat ttgtcagagt
      361 tcgatgaggt tgtggaaaat accgcaaaca ttgattatcg tgtgaatggc aatcagttga
      421 taatcagccc aaatgccaat tcaaaagaaa gtggtgtgtt gacgcttaag aaatctgctg
      481 gtaccggaac acctgtcgcc tataaaaagg ctggccaaca gactttaatg gccggggcga
      541 tcgataagcc gaacacttat acggtcaaaa ttgatgtgga aatggagggt tctttgaaga
      601 ttaaaaaagt tgataaagaa tcgggtgata ttataccagg aacggttttc catttagact
      661 ttggaaaaac tttacccgca aaagacgtga ccaccgataa agaaggcatt gcgaccttag
      721 atgagattcc tcatggtaca aaggtaacca ttactgaaaa atcggtgccg gcgccttata
      781 cgattgatac cacacccatg actgccacaa ttaaagcagg tgaaaccatt tcagtgactt
      841 caaaaaatac gcgagaaaaa ggtcaaatta ttctggataa aaccggaatt gaaacaggga
      901 gtgatctttg gaacgataat tactctttag cgggcaatac gtttgccatt cgcaaggata
      961 gcccaactgg tgaaatcgtc caagaaatga ccacggatga aaaaggtcat gcagaaacac
     1021 caaaagagat tgccaatgcg ttggaattgg gaacctacta tgtgactgaa accaaggcta
     1081 gtcatggctt tgtgaatact ttcaaaccag taaaagtcga attgaattat gtcaatcaaa
     1141 cagtggctct tgttaccagt aacgtaaaag ggcaaaacca agaaattact ggtgaaacca
     1201 ctttgacaaa agaagacaaa gataccggtc atgaaactca agggaaagct gagtttaaaa
     1261 gagctgaata caccttgttt actgttaagg atggaaaagc ggtcaaatgg accgagaact
     1321 ttaaaccaga attgttgaag ggaacgaaag cttctgatga aaccgtaact ttgactttag
     1381 atgaaaagaa tcaagttgcc gttaaacact tagcgattaa tgagtattac tggcaagaaa
     1441 ccaaagcgcc tgaaggatat accttggatg aaacaaagta tcctgtatcc atcaaaaagg
     1501 tggatgatag cgaaaaaaat gctgtgatta ctcgagatgt tgcggcaaaa gaacaagtga
     1561 ttcgctttgg ctttgatttc tttaaatttg ctggatcaac tactggcact gccgaaactg
     1621 gcttcaatga tctaaccttt aaagtgtcgc cattggaagg aaccaatgaa atcaccggtg
     1681 ccgaagatga agcgaccaca gcttataacg agcaattagg gtttgatggt tatggcaagt
     1741 ttgaaaatct tccttatggg gattatttac ttgaagaagt agaagcccca gaaggttttc
     1801 aaaagattac gccattagaa atccgttcta cttttaaaga aaataaagag gattatacca
     1861 agagtgatta tatctttact attaccgaaa aagggcaaaa gcaaccgatt aaaacggtaa
     1921 cggtccctta tgggaatcta accaatgaga atttctcagt cagtttgaac cgtttgatgc
     1981 tttatgattt gcctgaggaa gaagatagct taacttctct tgcgacttgg aaagaaggag
     2041 ataaagaatt gactactctt gattctaccg agctagtcga taaattgagc tataatctac
     2101 atgaaatcaa agaagactgg tatatcgtag ctcaagccat cgatgtagat gctacaaaag
     2161 ctgcccaaga aaaagataaa aaagccaaac cggtggcgat tgcggaaaca accgcaactt
     2221 tagcgaataa agagaaaaca ggaacttggg agattctgca taaattaact gtcgaacaag
     2281 ttttagacaa gaccattgtc ttattcaact atgtgtatga aagcaaagaa gcctatgaag
     2341 ctggtgatga gccggtagcg aaggatgcta gcttgaacaa tcaagcgcaa actgttaatt
     2401 gtatggtgga acgtcatgtt tccatccaaa ccaaagcgca cttagaagaa ggttctcaga
     2461 cctttactca tggtgacgtg gtagatatgt ttgatgatgt atccattacc catgatgtac
     2521 tagatggctc aaaagaagct tttgaaacaa ttctgtacgc tttatttcca gatggtacaa
     2581 gtaaagaaat ttggaaatct ggcaagattg attacgaagt gaatgacaaa gaatttacca
     2641 aaaccgtact tgcggaaaaa gtggatacaa gtaaatatcc agaaggtaca agttttacct
     2701 tcaaagaaat taactatgac aaagatggga atatcaatgg aaaacacaat gaagatttga
     2761 aagaaaaatc tcaaacttta acgcccaaaa aagttccgac aacaccaagt acaccagaac
     2821 aatctgaaat gccaactgtt ccaagtggct ctcaagaatc tagtcctaca gtgaaggcat
     2881 tccctcaaac cggggagaaa acttccaatg tgctactgtt cattggcttt agcttgatct
     2941 ttgcgacggc tggctattat ttttggaatc gtcggaacta aggtgataag atgaaacatg
     3001 taaatagtag aaaacaatac gcgcgaccgc ctcctaaaaa agtggtcgcg ctatttttgt
     3061 attcaaaact aacaatgaaa agaggaaaaa atatggaatt gaaatttgtt gtaccagata
     3121 tggtcgagac gttcggaaaa ctaacatacg gtggtgaagg tgaagttcta tcggaagggt
     3181 atggtcgaaa tactacaatt gttggtcgaa gttaccatct gttttcaaat aaacaacggg
     3241 ccgatgatat tgaagtggtg gtagctgcgg aagccggcga aaaggatttt gaccaagatc
     3301 aaccactaaa agctgtaaat ccccacttaa ttgccaaagg ctatgaaatt gagaatcgtg
     3361 ggtttaccga ttacgtgttg tatgttgatg atttagtgaa agcataggag gaaaagaaga
     3421 tgagattaac agaaggtatt gtcgtagatt caggattaac ctttggcaag ttgcgttttt
     3481 ccgcattacg tcgagaagta cgcaagcaaa atgaggacgg aacggttagt aacgaggtaa
     3541 aagaacggac ctataatttg aaatcctccg cgcaaggtcg aatgatccaa gtcagtattc
     3601 cagcaaatgt acccttacgc gagtttgctt atgatgcaga ggtagagctg gtcaatccaa
     3661 tcgtggatac ggtcgccaat tatgtttttc gggaaggaac caccgttaat tggtttatca
     3721 aggcagatga tttagtcttg aaacgacaac tgaatcaagg aaaacctacg aaccaaaatg
     3781 aaggaaagaa ataggtgaag aatatggaaa ttaatgttga acatatttta gattgtctcg
     3841 atcaatttgg caaaggtgag ctaacggagg aacaactcac taacgcatta acctatgatg
     3901 aaaaaatgtt tctgattatg catcaagggt tactggaagt aggtaacgat gccaaagaag
     3961 actttgatgt actggattgg ttaggggaag aagagtcttt ctttatggtt gtcgaggtaa
     4021 atgaaagttt atgtcggcag gcagaatctg ttttggaaga aatcgatgtg gagatgccgg
     4081 atgccatcga aagattttta aaacaattag tggaaacgaa acaacttccc gtagtagtaa
     4141 atgactagca taactttttg aaattgccca atgaaatcct attgggcttt ttcgactgga
     4201 ggtggaaacc atcaaaatgt acaaaggaca tcgcatacgc gcaggagatc aacacttgat
     4261 ttatcacttt gttcttggct ggctaatctt tttgttcatt ggttggatga gcgtctttta
     4321 tttacaagaa cttagacaat ttgatatttc taaggtatca ttttccacta gtgaaattgg
     4381 ctggtctatg aaggatgtaa tctgcttgct aggaagtctc gctctttcag gaagcatgat
     4441 gttactttat atacactttt ttcaggatca ttggcgaagt ctttggcatc gacaaaagtt
     4501 agctcggatg attctagaaa accattggta tgaagtaaag cagactcaag gtgaaggttt
     4561 tttcaaagat ttgaatagta gttggaccaa agagagtatc agttacttcc ccaaaattta
     4621 ttatcgaatg aaagatggct tactttctat tcgcgttcaa atttcactgg gaaaatatca
     4681 ggatcagcta ttgaagttgg aaaataagtt agaaagcgga ctgtattgtg agttagtaga
     4741 aaaagaactc aaagactcct atgtggaata caccttgtta tacgatatga ttgccaatcg
     4801 aattgggata gaagaaatag tggcagaaaa tggggcgttg cgattgatga aaaatcaagt
     4861 atgggcgtat gattccttgc cgcatatgtt aattgctggc ggcacaggtg gtgggaagac
     4921 ctatttctta ctcaccatta ttcaagcact attgaagtca gatgcagaat tgtttatcct
     4981 cgatcccaaa aatgcggacc tcgccgattt aggtacgata atgcctcacg tatactccca
     5041 aaaagaagaa atttctgaat gtgtggaaga tttttacgaa cgcatgatag ctcgtagtag
     5101 gtcaatgaaa gaaatgccca actacaaaac aggagagaat tatgcgtatc tcggacttcc
     5161 gcccaacttt ttaatctttg atgaatacgt ggcttatatg ggtgcgaatc gttttcctac
     5221 aagcatcgaa tagatgtgaa atggaagcct attgagatta tcaatagtga caactaatgt
     5281 tttgagagat ggaatgaaag ccttcaagtt gagctgaaac atccccgcta atactcctac
     5341 atgctctaat caatgaagta gattggtttt ggtatgaagc taggtgaagt cgtctgaaat
     5401 ctgcctaagt gcttgagcat aaggctgact atagggcggg cggctgaaaa agataactat
     5461 ggtaagaatg tctgaaaatg actgacgaat ctgcgaatgt acgggtctaa aaggctgatc
     5521 ttattgaaag ataggaacat acggacgtat ggtgagatac cgacaagtaa ggttccatga
     5581 tatgaaaatc gggatagcta acgaagaagc tataatttca caggctcata gtagatacct
     5641 aaggttatac atgatagcta aaaacattgg aacgatgtaa gcagaaaact atcaattaaa
     5701 tgactacttc tagataggtg catataagta ataacgaaat tgctttgttt ctgtgaaagt
     5761 aagggcacag taccgatgaa gcgtctaaca aatgtggagg gatagcccta agtctattta
     5821 ataacaatga atgttgaaac agatgaagtt caaggatctg gtaagaacgt gggaaaatcc
     5881 gttatggagg tgccacgctt gaacacaaaa atacgttact gggaatatta tgatctacaa
     5941 gaaacattcg atcagctatt tactcaaagt agaaacggga aaaagtttta tcaattatat
     6001 gagttaatca tttctgaaaa taatattctt ttagcatacc gtactatcaa ggcaaacaag
     6061 gggtcttcga caccaggaac ggattccttc acaattgata actataagga aatgaaccaa
     6121 gcagagttta tccatcttat tctcagtcat ttagaaaatt acaaaccaaa atccataaag
     6181 cgagtaatga tacctaaacc caatggtgag aaacgcccat taggaattcc atgcatgatt
     6241 gatcgaatga tccaacagat gttcaagcag atactggagc caatatgtga agctaagttt
     6301 tatgaacata gctacggttt cagaccattg agaagtgcaa agcatgctct aggtcgcatt
     6361 atgtatctca taaacatcag taaaatgcac tatgcagtag acattgatat caaaggtttc
     6421 tttgataatg taaaccaccg tttactgata aaacaattat ggaatatagg aatttgtgac
     6481 aaacaagtct tagctattct ttcaaaatct ctgaaatcac ccattcaagg agaaggtatc
     6541 ccgagcaaag gaacgatcca aggaggtatc atttctccac tattatctaa tgttgttcta
     6601 aacgacttag accattgggt ctcaaagcag tggcatacct ttgaaacaaa gtatccctat
     6661 actaaaggtt acaataaatt tcgtgctcta agagatacaa atctaaagca aggctatatt
     6721 gtcaggtacg cagatgactt taaaatcatg actaatgatt atccgacagc attaaaatgg
     6781 ttccacgctg tcaagcttta cctaaaagac agacttaaat tagatatttc caatgagaag
     6841 tctaaaatcg tcaatttgcg taaatgtaag tcggaatttt taggattcgc tatttgcgtg
     6901 aaacaaaaag ggaaaaaatg ggtttgtaat tcacgtattt ctaacaaaaa aaaggatcag
     6961 attaaagaag agattaaaca aagaatcaaa gatattcaaa agagtcctac agcacaaaat
     7021 gctctcctgt ttaatgctct cgtgctcggt gttcataatt atttcaggta tgccactcat
     7081 attaatttag atttgaatag gatgaactac gttctttcat tcactactta caaccgatta
     7141 tcaaattgta gtacaagatg ttaccccaac aaagcttccc caacttacaa aaagttttac
     7201 tcaacaacga tgaaaacgta taaagtagct ggagtctatt tgtaccctct ttgcgacgta
     7261 tctacaaaaa caatttacgg atttaatacg gaggatacac cgtttactcc gtttggtcgt
     7321 caaagattgg agcacaaaag cctacagtct cttgtgttcc aagaattaag aaaattgatg
     7381 gaatcgaaaa taccgaatag aacggttgag tatttagata gtagaatatc tcgttactca
     7441 atgaaatcag gcaagtgtga gattacaaaa caatttttgc cagcaaaagc cgttcactgt
     7501 catcactatt tgccaaaaag tcttggtgga gacgacaaat tcgataactt gagaattatt
     7561 cataaggata tccatcttct gatccataca acaaataaaa tgataatcga tcactacgtg
     7621 catgaactga aactggtgcc agagcaaata gcaaaaatca acctttatcg aaagatgtgt
     7681 aatctgcaaa acattcaata gaaaataaat agatggaacg ccgtatgagg tgaaagtctc
     7741 acgtacggtg tggagcgggg gaaaagatgg agattatatc aaattcttac ctatcgctat
     7801 agatgttaac gacaaaagaa agtgcggtga ttttgaataa gcttaaacaa atcgtgatgt
     7861 taggccgtca atctggtttc tttctgattc tagcttgtca aaggccggat gcgaaatatc
     7921 taggagatgg gattcgcgat cagtttaact tccgtgtggc tttgggtcgt atgagtgagc
     7981 ttgggtattc catgatgttt ggagaagtcg ataaaaattt ttttatgaaa cgcatcaaag
     8041 gacgaggtta tgtagataca gggggcagtg tgattagtga gttttatacg ccacttgtac
     8101 caaaagggta tgatttctta agggaaatta gcaacattgt tggattaacc gttcatacgg
     8161 aaagagaaaa taatagtgtg tagcctagga atatcaataa tcctgggctt ttttattgag
     8221 gtgatttatg acatttttag atttattcgc cgggattggt ggctttcgct taggtatgga
     8281 acaagccggt caccagtgta tcggtttttg tgaaattgat gaatttgctc ggaggagtta
     8341 taaagcaatc catgatacaa ggaaggaggt ggaaatgcat gacatcacaa gtgtatcaga
     8401 cgaatttgtt cgatccctcg gaccagtgga catcctttgc ggcggctttc cgtgccaagc
     8461 tttttcaatt gcgggaaagc ggcaaggatt ttccgatact cgaggtactt tattctttga
     8521 aatcgctcgg ttcgccactc ttctccaacc taagtttcta ttccttgaga acgtccgggg
     8581 attgctcaat cacgaaggag gggctacgtt cgagacgatc ctccgaacgt tggatggatt
     8641 ggggtatgat gtggaatggc aagtgcttaa ctcaaaggcc tacgttcccc aaagccgtga
     8701 gcggatcttc cttatcggac attctcgaga tgcatgtacc gaacaagtat ttcctatcat
     8761 tggatcgtct tcaacatctg atcaaaacat cagaaacttg gtaaatatca atccttccaa
     8821 tcgaggaatg ggtggccaag tctatggttc agatagcgta gcaccaacct tgaccggtga
     8881 tgaaggaatt aaaattgcct taccggtaaa ggatgggatt tctgtagcgg gtatgttgtc
     8941 gggaaatttt gaacaaggca ataggattta tgaggtaacc ggaacagccc ccactttgtc
     9001 aacgaaacaa gggggaacga agattatgat tcggaaaaat gaaacagaat atcaagaggt
     9061 gaagccaggg gacagtgtga acctggcttt tcctaattcc acaagtcgcc gaggtcgtct
     9121 gggaaaacaa agtgtgcata ccttactaac aggagaccaa caagcggtag tcacggatca
     9181 gtaccagatt cgaaagttaa cacctaggga gtgctggcgg cttcagggct ttccagattg
     9241 ggcttttgat cgagcttctc aagtcaattc agatagtcag ttgtataaac aggccggaaa
     9301 ctcagtaaca gttccggtca tttttgatat tgctagaaga ttaaaggggg taaaagcata
     9361 tgatttatga cgagttgatt ggagaaatct actggatgat tggcaagatt caggcagatc
     9421 cgaaattgga agaagaactg taccggctca attttgatat tcgcaaaaac ggggtgaaag
     9481 tccaggtgat tcgtatgtag tggatgagga aacggatgct cgaatggagc tcaatcaagt
     9541 catcggtgaa ttggaacgaa ttgcggacct tgccaaagaa cctgatatcc gccaatactt
     9601 gtttgagata aaagcagagt tggaaattga gggtatcacc gcggagtaat agggaaataa
     9661 cccactgata ggcactgacc gcgggggatt tgcgaagcag aaatcctccg tggtgctgtg
     9721 cctgttcatg gacggcggca gccggccatg atgtctcacc ccccgtatct aacagggggg
     9781 tacaaaaaca caaaaaacaa gcaagtaacc ataaaaaatg cttgttgtat caaggatatt
     9841 aagtaatttg tataggtgtt aactcatttg gaaaagttaa caccttgaat ttggaggtga
     9901 aaacttggcg caacgaaatt tagattatcg gttattaaaa gaacgacgca acgaatatgg
     9961 cgtttcacaa aataaattag ctactgcttg cggacttagc cgcccatacc taaatcagat
    10021 agaaaacggt ggcgtaatcg cctctacaaa gaccatgaga aaaatttttg atcaactgga
    10081 aagtttcaat cccgatttac ctttaacgtt actatttgac tatgtaagga ttcgctttcc
    10141 cacaacggat gtgcggaaaa ttattcaaga aattctccat ttgaaattcg agtatatgct
    10201 tcatgaagat tacgcctttt actcctatca agaacaatat gtcatgggcg atattgtagt
    10261 gatgttatct catgaagaag ataaaggtgt ccttttggaa ttaaaaggtc gtggttgccg
    10321 gcagtttgaa acttttttac tcgcccaaaa gcgtagctgg tacgactttt ttgaagattg
    10381 tctaaaagcc ggtggcgtga tgaaacgctt ggatttagca atcaatgatc gagtggggct
    10441 actggatatt cctgatttaa cgaaaaaatg tcagaaggaa gaatgtatct ccttgtttcg
    10501 taccttcaaa agttaccgtt ccggggaact gttgaaagct gatgaaaagg atggtatggg
    10561 caatacctta tatattggca gcctcaaaag cgaggtttat ttttgtttgt acgaaaaaga
    10621 ttatgaacaa tatatcaagt tagggattcc attggaccag accgaaacga aaaatcgttt
    10681 tgagattcgg ttgaaaaatg accgtgctta ttatgcgatt caagatttgt taaaaggtcg
    10741 tagcattgaa agtaccacgt tttccattat caatcggtat ttgcgatttg cggataaagt
    10801 agatggaaaa cggcgaacca attggccctt gaatgaacaa tggggtcgtt ttattggacg
    10861 gaatcggaaa gagattcaat taacttctga accgaaaccg tataccattg aacgaacatt
    10921 aaattggcta ggtagacaag tcgcccctac gtggaaaatg gctaaggagt tggatcgatt
    10981 gaatcaaaca acgtatatcc aggatatggt acagaatgcg cgactctcgg accggcataa
    11041 aaagattttg gagcaacaaa gtatggcaat cgaaaacttg attgtatgaa aagaggaatt
    11101 ttgatggaaa ttgtaaaaga tatgttattg gtacttggtg gcagtatgct tggtgttacc
    11161 gtgatgtgct tgatgaatgc aagtgcagca gcggattgag caatggaaaa gaaaggaaag
    11221 tgacaaaatg aatttcggac aaaattt
//
LOCUS       DADGKS010000083        11127 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.084, whole genome shotgun sequence.
ACCESSION   DADGKS010000083 DADGKS010000000
VERSION     DADGKS010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11127
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.084"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(99..1229)
                     /locus_tag="JXV47_002419"
     CDS             complement(99..1229)
                     /locus_tag="JXV47_002419"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HAX1488432.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     gene            complement(1878..3080)
                     /locus_tag="JXV47_002420"
     CDS             complement(1878..3080)
                     /locus_tag="JXV47_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAX1488433.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="JXV47_002421"
     CDS             complement(3140..3343)
                     /locus_tag="JXV47_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAX1488434.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="JXV47_002422"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="JXV47_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            4880..5692
                     /locus_tag="JXV47_002423"
     CDS             4880..5692
                     /locus_tag="JXV47_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1488435.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6716..6868)
                     /locus_tag="JXV47_002424"
     CDS             complement(6716..6868)
                     /locus_tag="JXV47_002424"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488436.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
     gene            complement(7059..7937)
                     /locus_tag="JXV47_002425"
     CDS             complement(7059..7937)
                     /locus_tag="JXV47_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAX1488437.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7976..9094)
                     /locus_tag="JXV47_002426"
     CDS             complement(7976..9094)
                     /locus_tag="JXV47_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HAX1488438.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9091..>11127)
                     /locus_tag="JXV47_002427"
     CDS             complement(9091..>11127)
                     /locus_tag="JXV47_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HAX1488439.1"
                     /translation="GNVTTSNEYSYYRNIPDVKGLTFDVSNQKTLANLDVCGTIQTLT
                     FYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVYHLSESDHRIEVDVIQDCLPRY
                     IHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETHESLQVSVKDVPSYQEKYSDQQ
                     NVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTFQESDIEKWLKETLNYFAQLFG
                     QLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNWGSYPATNRIWNKDMYYASLPF
                     TMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSNSLSSALLASLYFEHTGDTKFF
                     ERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDAFALGKYHTGSNLCLWKACIGL
                     AEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPFGEQFLEGIGDEEKTTYSVKHY
                     QKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMPFYQFLDNKDHLYQNTMAFSAS
                     SFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNPQAFVTRLEELICLADLDGSWW
                     WWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQYFGLKFKKGVLQIDPVDNLTFS
                     WKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKKILHVEKGKTIHIQRRKR"
BASE COUNT         3375 a         2343 c         1807 g         3602 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaaattatc
     6481 aatcatttca aggtaatata actacctgag tttattatcg attaaaatgc taactacatt
     6541 tgcaagagaa gcgagagtta aaggtaaata tagaatttct acttttttag caatagaaat
     6601 aggaataaaa tatttaaaat gtatagaaac tttctttttt tttcttgcta tctttttata
     6661 atcacaactc tctataatag aattacgatt tattttatac ggctgaaaaa atctatcacc
     6721 aaaaaaattc aaacattaag ccaaggatta tgaagtcaac atttcgaaaa atgaacatac
     6781 attggtaagc aactataact attaccacag acataaagta acacaatata ttactattta
     6841 agtgtacgcc accagtgaat atcctcaagg tatacagcgc acaacaaaaa gaaaaaagga
     6901 aacgcagaag catttccttt cagtgattta atgaaaacaa cacgatttga cttagagcct
     6961 ttttatttga attcattttc gctttatcca acttcatttg atcatttgat tactcggtta
     7021 aatacttttg acatgagtat caatgaaaca ttcattaatt atggttgctt atttcttacc
     7081 gcttttctgg ccaatgctaa tccgccgatt attccggcat tatcacctaa ttcgggcgta
     7141 ataatgtagc tatcaattgg tggtatttca acatatccat ttataagctc aacaaattta
     7201 tcctgaactt ttttcttcat gtgttcttgt ttcattacac caccgccaaa aataattcta
     7261 tctggcgaaa acatcagtgt tgtattgtat gcacattggg caaggtaaaa ggcttcaatc
     7321 tgccaaaacg aatcgtcagc caataaattc tggcctttta cacccaaccg tttttcaatc
     7381 gctggtcctg ctgccatccc ctctaaacaa tcttggtgga agggacagtt tcctgaaaaa
     7441 ttgtcctttg gatgtcgctt gatcaacata tgccccattt ccggatgact gaacccttcc
     7501 acgaaagtcc cattgaacaa ggcaccacct ccgatacctg ttcccacagt gaagtatgca
     7561 acacctgcta accctttgcc agaaccagca acatattcac catagcaagc cgcattgaca
     7621 tctgttgtcc attcaatcgg aatattgaaa tattgcttta gcgttcctac aaaattgaaa
     7681 ttttgccaag caagttttgg tgttgatgtg atatgaccga aactcgttga tttgcattga
     7741 atatcaattg gaccaaagca gccgaccccg atgcctgcca attgttcctt aaaaggttta
     7801 aaaaaatcaa tgacctgctt cattgtttca actggagttg ttgtgggaaa actgactctt
     7861 tccaaaatcg ttaattcctc agtaccgact gcacagacaa atttagtccc tccagcttca
     7921 attgccccat atatcatcat aggttcctcc cttcgaatat gtgaaaaaca cttcattaac
     7981 gcggcaagcg ttctcgatca gtgaaatgac gtttagtatt tcctgaagct tctgttgaat
     8041 accagtaagc gacactagca acatcgtctt gccgctcaaa taagcgaaca tcatcgttgc
     8101 cgatttgttg taaagtgacc gataaatctt cggtaaaaca gatggggtct tgaagatgcc
     8161 aacgataaag accatgtcgt ggcattgcgt cgtcaccaaa ggcatgaacg gcattcaatt
     8221 ttcccgtttc aaaacgatct cttgtggcat ctctatttga ttggtaagga taccctaaaa
     8281 aggctgttga atagtttttc gcatgtggac gtccgaactc atcgtactca tgaaaggccc
     8341 acgccccgcc aaaataatct tctgaacctg ttgaggttac ggtcggatac tcactatccc
     8401 catcaatgta gaatttaaac tcgccttcgc cccaccaata acgttctagg caggtaagcg
     8461 caaggtaagt acccacgtaa tagccttgac cctttaatcg atcaattaac ttataatcct
     8521 cctgtaattt ggtaatgcgt tcccgatgcc aatttgcgtg aaaatatagg ctattttctt
     8581 ccaattcgtc caccaaagcg taatttatcg tataaaaaaa tgaggacata tccttcggat
     8641 gtaaattctc gatcgtaatt ttagcggatg tttggaaagg catttcgaaa taggaattaa
     8701 agccccctgt aggattaacc actatcggca acgagttcac ctcgcaacgc tctccaaacc
     8761 cattacaaaa gaaatcccct aaaggacttt caacagcagg gctatccgac ccatcccaat
     8821 aaattcttaa gattaaatca cgtaaaacaa aactgccaaa ttctgttcga tcacgaatcg
     8881 tcatccacat atgacgaatt attcccgttc cagtaatatc cgcaatcaca gtttcttcac
     8941 cagaagtcag cggaattgcg ccacgacctt tgcggcttgg tcctagctcg cttggcaaca
     9001 tcgcagcttt acctttctcg cctgttggat tttcgggagt gattgctcga ctctggattt
     9061 ttttaaattg ggtaatattt tttagtatac tcatcttttt ctcctttgaa tgtgaatcgt
     9121 ttttcccttt tctacgtgaa gaattttttt cgtatcactt attttcaatg gcttttctga
     9181 caaatttgaa atactcaact cggattgcgt acattcaatc gaaatgaagg cttgaccgaa
     9241 cttcaaattc ttccaagaaa acgttaaatt atcaacagga tcaatttgca atactccttt
     9301 tttgaatttc aatccgaaat attgactgat cattaggctg acaaaaagac ccgatgccca
     9361 gccgcatttg ccgcagccaa agtctcgcac gacttctcct tgttgagcct ctaagcgata
     9421 cggccaccac caccacgaac cgtctaaatc tgccaaacaa attagttctt ctaatcgggt
     9481 tacgaaagct tgagggttgt gcagctcgct cattaaaaca gtgataaagc caggaaaagt
     9541 ggcgccggat tctaatcccc aagtgatgcc tttgatttcc tcgctatagg ttggattgaa
     9601 agaactagca gaaaaggcca tggtgttctg atataaatga tctttattat ctaaaaattg
     9661 ataaaaaggc atcaacgtag tgtctgattc ttctccatca tgcatcaata aattaatttt
     9721 tccatccaca atcacatcac ttaaaaagat taacccttgc tcaagaatcg gtttttgata
     9781 gtgcttcact gaataggttg ttttctcctc atcaccgatt ccctccaaaa attgctcacc
     9841 aaaaggacca tcgatagtca tttgtttaca aattgattcc tttagtttac aggcaatgtt
     9901 tttgtatcgc ttgctaagac tcagttgttc tagggcttca aaaatttctg caagtccaat
     9961 acaggccttc caaagacaaa gattgctgcc ggtatgatac tttccaagtg caaaggcgtc
    10021 tgataaccaa acagatggaa aaagcattgg ttcccctgac cgacgttgag ctaatatgtc
    10081 ctcaataatt cttgaagcat tcagtagaac ctgcggacac cgctcaaaga attttgtatc
    10141 cccagtatgt tcaaaataaa gactagccag taacgcactg gataacgaat tactcagaga
    10201 atgattgata cctcctgtaa attttgaacc aggaaactta acgccatatt gatcaaacca
    10261 tagaaccgtt ttttgacata actccggttc aaacatggtg aatggcaatg atgcgtaata
    10321 catatcctta ttccaaattc gattagtagc aggatagctg ccccaattgc tgccgacgac
    10381 ctgtccctgt cgattcatac cgaaactaga aaagctttga taaagtgcac gacgatagag
    10441 atggacaact ctatcgtttg gcattgacag ctgcccaaat agctgagcaa aatagttcaa
    10501 tgtttccttc agccattttt cgatatcaga ttcctgaaaa gtcattactt cttcaaaagc
    10561 atttgggtcc acaaaagcaa tggcgaagct tgccacttcc tgttgtgcga tcgtgtcctt
    10621 atttcctttt tgagaaatca acacattttg ctgatccgaa tacttctctt gatacgaagg
    10681 cacatctttc actgaaactt gaaggctttc gtgtgtttca ttcacaatgt aaacctgttg
    10741 aacaagcata cttaaacgct tattagccag tatgggagca aaggatacta caatgacctt
    10801 aaacgtcgaa taatgatgaa tatatctagg caaacagtct tgaatcacat cgacttcaat
    10861 acgatgatcc gattctgaca aatggtagac aatcccgttt acttcaacct ttaaggataa
    10921 cgaattggtt tgagagagct gtttattgac ccaaacacct ggtttttcct cagttagtaa
    10981 attttctcga taaaaggtca acgtttgaat cgtcccgcaa acatcaaggt ttgctaatgt
    11041 cttttgatta cttacatcga aggtcaatcc ctttacatca ggaatattcc gatagtagct
    11101 gtattcgttt gaagtagtca catttcc
//
LOCUS       DADGKS010000084        11094 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.085, whole genome shotgun sequence.
ACCESSION   DADGKS010000084 DADGKS010000000
VERSION     DADGKS010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11094
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.085"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            33..656
                     /locus_tag="JXV47_002428"
     CDS             33..656
                     /locus_tag="JXV47_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488440.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1106..2155
                     /locus_tag="JXV47_002429"
     CDS             1106..2155
                     /locus_tag="JXV47_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAX1488441.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2152..3033
                     /locus_tag="JXV47_002430"
     CDS             2152..3033
                     /locus_tag="JXV47_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1488442.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3036..3806
                     /locus_tag="JXV47_002431"
     CDS             3036..3806
                     /locus_tag="JXV47_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAX1488443.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4085..4939
                     /gene="aroE"
                     /locus_tag="JXV47_002432"
     CDS             4085..4939
                     /gene="aroE"
                     /locus_tag="JXV47_002432"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HAX1488444.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5117..6280
                     /locus_tag="JXV47_002433"
     CDS             5117..6280
                     /locus_tag="JXV47_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAX1488445.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6397..6807
                     /locus_tag="JXV47_002434"
     CDS             6397..6807
                     /locus_tag="JXV47_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAX1488446.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6981..9209
                     /gene="topB"
                     /locus_tag="JXV47_002435"
     CDS             6981..9209
                     /gene="topB"
                     /locus_tag="JXV47_002435"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAX1488447.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9347..9664
                     /locus_tag="JXV47_002436"
     CDS             9347..9664
                     /locus_tag="JXV47_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488448.1"
                     /translation="MKKVHSFLNYLMGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAY
                     SPTLILSTLTAGAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQ
                     YFG"
     gene            9824..10060
                     /locus_tag="JXV47_002437"
     CDS             9824..10060
                     /locus_tag="JXV47_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAX1488449.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10057..10455
                     /locus_tag="JXV47_002438"
     CDS             10057..10455
                     /locus_tag="JXV47_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HAX1488450.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
BASE COUNT         3876 a         1834 c         2304 g         3080 t
ORIGIN      
        1 aataaaaaat aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat
       61 cgagagtaca agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt
      121 attttcgacg tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt
      181 tattgccgga aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa
      241 ccagcaaatt gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg
      301 cgatatcggt gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt
      361 ttaatgatcc tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt
      421 atgatgtaca tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt
      481 tctttgatgg aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt
      541 ttgataagga gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag
      601 aagaagaatt ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca
      661 ttggcgcgat gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg
      721 tttgatcttc aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt
      781 cgattagact taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt
      841 atttcagcag aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg
      901 agactttccc atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga
      961 catgaacatt gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga
     1021 ccgctttggc cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa
     1081 agattgactt tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat
     1141 tattttagtt tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag
     1201 tacttcgacg aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca
     1261 tccggcatta gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa
     1321 agaaggagaa aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc
     1381 cacaatgagt caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc
     1441 tgccgctcaa tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac
     1501 ggatcctgtg ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg
     1561 tgtttctgat cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa
     1621 tgcaaaaaaa gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc
     1681 acaagcagaa gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc
     1741 cactaatgag attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt
     1801 tccattagat aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc
     1861 aaatatcccc gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat
     1921 cgggatcaat caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag
     1981 tggaaaagaa aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat
     2041 caatcaatct caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc
     2101 caaaatcatt acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta
     2161 tcagctattt cacaaggcat gctttgggca atattaggat tagggatttt catgacttat
     2221 cggatcttag actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc
     2281 tgtgtgacag ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt
     2341 gctggcatga tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt
     2401 attttagcag ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga
     2461 acaccaaatc tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg
     2521 ttacctgatt actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct
     2581 gtactgctat tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac
     2641 gaaacgatgg ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact
     2701 ttgtcgaacg gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca
     2761 gatgtaaata aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa
     2821 gtgatcttcc aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc
     2881 atttatcagc tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag
     2941 ttgttctccg ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg
     3001 aacttaaaaa cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa
     3061 atggcagaaa agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta
     3121 accttacaat cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa
     3181 gcacactgtt caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta
     3241 aagatcagct gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt
     3301 tccaagaccc caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg
     3361 cacaaaaaag aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag
     3421 attttttcag actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag
     3481 cgggtgaatt atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag
     3541 ctcctgagtt actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag
     3601 cattaatgcg attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca
     3661 cgcatcgaat ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga
     3721 aaatcgttca agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc
     3781 agttctttga agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact
     3841 tgaaaactca ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa
     3901 catatttggg tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt
     3961 ctttgctctg acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc
     4021 gtactttttc gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa
     4081 taagatgatt tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag
     4141 tttatcccca ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt
     4201 agctttccaa gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga
     4261 tatgttaggt gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga
     4321 ggtaagccag gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg
     4381 tttgattggc tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat
     4441 ttcgatcaaa aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac
     4501 tgttcaagct gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac
     4561 attcgctcaa gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa
     4621 agttcgtgac tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct
     4681 agtcaatgca acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat
     4741 aagcatgatg catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg
     4801 tttattaaaa gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat
     4861 ctaccaagga gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat
     4921 tgaaaagctg tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg
     4981 gtctcaagaa aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat
     5041 tatcaaaaaa tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa
     5101 acgaggagga accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa
     5161 acctctgaag cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat
     5221 ggaaaatgag gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt
     5281 gaaccaatac gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa
     5341 taaaaaattt ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc
     5401 gtggaaaaaa atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt
     5461 ttttattggt aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac
     5521 ctttcatggg caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac
     5581 acgcggagaa gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc
     5641 ccataagccg aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg
     5701 acaaaataag atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt
     5761 agtagaaaat tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga
     5821 aaaagtgatc gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa
     5881 tctggatggt gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca
     5941 gtacgcacgt ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca
     6001 agtaatgaac gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta
     6061 tgcagctggt aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa
     6121 aaacctcttt tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga
     6181 cggttcgtgg aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca
     6241 aatgaatcaa tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag
     6301 aagctgcgca aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc
     6361 ttatggtaga tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa
     6421 aatgagtcgc gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt
     6481 atcaccacat acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa
     6541 aatctaatca cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg
     6601 ccagaaggaa ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca
     6661 agaaatgaag aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag
     6721 atgccactgg atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc
     6781 atcaactggc agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa
     6841 gcagcaaacg gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt
     6901 atcttttttt tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat
     6961 taagtaacgg aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa
     7021 aagcctatgc cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg
     7081 atccattgtt tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg
     7141 ttgctccagg agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt
     7201 tcccagaaac cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa
     7261 aacgagaatt gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg
     7321 aagccatcgc gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt
     7381 tacgtttatg gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc
     7441 aacctggaaa gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt
     7501 ggctgattgg aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg
     7561 atggcagttt ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc
     7621 aagaagaaat caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga
     7681 caaacaaagg gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag
     7741 agttaacgaa ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc
     7801 ttgaagttac gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt
     7861 tgcagacaaa gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc
     7921 aaggattgta cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag
     7981 aaaatgagca tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag
     8041 aagaagtaca gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc
     8101 aagaacatca tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc
     8161 tttccaaatt acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg
     8221 ctgcagatta tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa
     8281 aaagcatcgg aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa
     8341 aaaagaaaga agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac
     8401 tgaaaagtat ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca
     8461 cagcaatgaa aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag
     8521 aagtagaagg aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga
     8581 agcattacat cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt
     8641 gtaaggcagt agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag
     8701 ggtacttgag aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca
     8761 aaaaattcat cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt
     8821 cagatgagat tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag
     8881 gaagatgtcc aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct
     8941 tgaatccgga atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa
     9001 cgaatctcag agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg
     9061 gtaaaaaagg gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt
     9121 cttttccatg gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa
     9181 gaaaaaataa tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt
     9241 ccgaaaagtg agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa
     9301 cgttggggta ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca
     9361 ttcattttta aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct
     9421 aaagtatcct gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc
     9481 accaacgttg attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca
     9541 taaaacgaca agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc
     9601 ggctatgatc attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg
     9661 ttaagaatac gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt
     9721 tcgtaagaaa aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa
     9781 tgtacttact atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa
     9841 gtataaaatt agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga
     9901 attcatgggt gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt
     9961 acgaatgatc aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa
    10021 tcaatatgaa gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa
    10081 attatcaaaa tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta
    10141 aaagatgcaa atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa
    10201 gaactctatc ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa
    10261 catccttttc ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa
    10321 ttgaataatt gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt
    10381 accactagtt cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa
    10441 accgcaataa aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa
    10501 ggaatatgct gattttttta tgtttaatca tacaaaatag ttttttcata aaaatatgga
    10561 aaatatggat taattttgaa ataattgatt taaaaggaat acaaaagagt gaatagtagg
    10621 aaatagtggt ttagaactag tgggctgatt ttttatatat tttagtttac ataatatata
    10681 ttatacaaag tagatttaaa aaatgataaa cctctctcga acggtttttt atcaaaaatc
    10741 gtcatttttc catcaaaatc tgcttatgca aaattataaa aaaattttgc agtttttctt
    10801 actttttttg tcgtttaatt gaatgataaa aaccagtttc tttattcagt taatcaaata
    10861 tgaacgaatt agatatgaat cattgtattt gccgttgcgg aaggattttt taattaacca
    10921 cagataaaca ttgataacga ttcgcttatt gtaatcaaca gattaaattt catatgttca
    10981 tatgtacgga tacattttcg gaccgattaa ttttaaccat tctatttatt tgcttaccta
    11041 ttagatatca ataaaaaact gcttaacagc tatttcagct gttaagcagt ttta
//
LOCUS       DADGKS010000085        10318 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.087, whole genome shotgun sequence.
ACCESSION   DADGKS010000085 DADGKS010000000
VERSION     DADGKS010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10318
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.087"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(71..904)
                     /locus_tag="JXV47_002439"
     CDS             complement(71..904)
                     /locus_tag="JXV47_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HAX1488451.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(1208..3373)
                     /locus_tag="JXV47_002440"
     CDS             complement(1208..3373)
                     /locus_tag="JXV47_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1488452.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            3633..5927
                     /locus_tag="JXV47_002441"
     CDS             3633..5927
                     /locus_tag="JXV47_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAX1488453.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            5920..6585
                     /gene="pgmB"
                     /locus_tag="JXV47_002442"
     CDS             5920..6585
                     /gene="pgmB"
                     /locus_tag="JXV47_002442"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAX1488454.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            6578..7585
                     /locus_tag="JXV47_002443"
     CDS             6578..7585
                     /locus_tag="JXV47_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAX1488455.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            7607..8626
                     /locus_tag="JXV47_002444"
     CDS             7607..8626
                     /locus_tag="JXV47_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAX1488456.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(8907..10274)
                     /gene="nhaC"
                     /locus_tag="JXV47_002445"
     CDS             complement(8907..10274)
                     /gene="nhaC"
                     /locus_tag="JXV47_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAX1488457.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
BASE COUNT         3198 a         2242 c         1909 g         2969 t
ORIGIN      
        1 ctctccaaac ggtataatcg tttggagagt tttattttaa tcagtttttt tatgttatat
       61 gttatatttt ttattcgttc acatctaatt cgatttccac cccgtagtga tcactgatga
      121 ttggactatc gatcccatca aaaatccgtt gatatttttt aacctgcatt ccttcaggga
      181 cgaaaataaa atctatacgc aatttttctg tattttgttc ccaaccatct attttctttt
      241 ccacagtagc tgcttttcct ttttcattcg cgacaacata cgaatcttga agaagaaggc
      301 aactttctct tacagtataa taaccttgag agtctactgg attattgaaa tcacctagga
      361 aaaaaagtgg tacgcgagtt tccaaaaagt agttttccaa gtttttccac tcaaaataaa
      421 agccactttt tttatctgtc caccaagaaa agtggcagct cgagacaaaa atgtcctgat
      481 catctatctt tgttttccca atcaagatct tgcgtgtctg ataatcttct ttcttttgaa
      541 attgggagac ggtaaggacc tgactttcca atgttttttt cgtaagcagt gcatttcctt
      601 cttcatattt atcataaccg atgtggctca tttcccaact ccaaaaatac tcttttccgt
      661 gttcctttaa aagctgaact aaacggtagg caaaattatc tttacggata ggtacttgat
      721 tctttaccgg acagaacttc attagcttcg caggttctac ttcttcagat tccagtaatt
      781 ggttgatttc ttgtaaagca atcacttcat aatcttctaa caggatctta tctgctaatt
      841 cttgcaattt tttctctggt tctggctcaa gccagctatg cgtgttgagt gtcatgaatt
      901 tcattggttt tctccttgtc ttcatttcga aacaaaaggg ttgtgacaaa atttttgtca
      961 caacctctcc agcaaatagt gttctcctgc taactcctca gtaataagct caatggacca
     1021 ggagctattt tttgtttggc tgtttttatc acttggtgca gggcagcttt ttcacgacct
     1081 ctccactaaa cagtattcaa actgctgctt ctcggtaata agcccaacca aacgaaaaat
     1141 aggaggagct atttttgttt ggctgttctt atgacttgat gcaggacagc tttttcacaa
     1201 cctctcctta cattttaatg gagccgatca ctttaccagc tgtcactgta cctaattgct
     1261 tgatcactac ttcttctact ttatcgtttg taaatacgat catgatcgtt ggatcttttt
     1321 cttcgttttg gatcacatca agatccatct cagctaattt cgttcctgtt cctacttctt
     1381 ggccttcttt gacagcaatc tcaaaagctg gctgattcat ttggactgta tcgattccca
     1441 tatggatcaa aacttcgata ccatctttcg tttccagccc aattgcatgt ttgctaggga
     1501 aaatacttgt cacttttcca gcgatcggcg caacaacttc tcttgatgtt ggaataacag
     1561 caaagccgtc acccatcatt ttttgtgaga ataccggatc ttttacttca gataaaggaa
     1621 tcacttctcc agaagctgcg gaaactagtt cttgttctat acctaagtat tgcttactac
     1681 ctgcttgtcc atttcctgta gaaaccattt ctggctctgg aatctctgct cctgattgca
     1741 gcagatcttc gatatctgat ttcaagacat ctgcttttgg tccataaact gcttggactc
     1801 cattgtcttt gacgatcaat cccatcgccc ctgctcgttt ccaggcttct tcagtcccta
     1861 ctttttctcg atcatttaca cttacgcgta accgagtcat acaagcatcg acatctttga
     1921 tattttcttt tcctcccagc aaatgaatga tctggaccac ttgctgatct gctgttcctg
     1981 ttccgctgtt agatacaacg gtttcttcac tgtcattgtc gtaatttccg ttacgtcccg
     2041 gtgtagcaaa gttgaatttt ttgatcaaga aatttgctaa gaaatacgta acaacaccaa
     2101 aagcgatcac acacaacacg aagttgataa gatctccacc tagacccgct ttgatagcta
     2161 acggtgtccg agtcagcaat tcgatattcc caaatgaatg gacccgcaat ggcaagatat
     2221 ctgccatcgc aaatgcagcc ccttggatca ctgaataaat gacatataat ggcacagcag
     2281 caaacataaa catgaactcc aatggttctg ttacacctgt tagaaagaca gccaacgctg
     2341 ctgaaaaata cattgattta tatcttgctt tcttatcagg atcgacatta cgatacatcg
     2401 caaaagccat tcccatcaag atacctgaag aaccaatcat ttgtcctact ttgaaacgag
     2461 ccggcgtcca gttatgcaac acaaactcat attgcgacat atcccctgca cctttaagat
     2521 tcactaaatc agtggcccaa gccaaccata acggatcttg cccaaatact tgtgtccccg
     2581 cctgtgcgcc tgataaaatc tcatacgatc cgccaagctg tgtatagttg ataggaatcg
     2641 tcagcatatg atgcaatcca aatggcaata gtaaacgttc taatgttcca aataaaaacg
     2701 gtgctagaat cggtgcgctt tcttgtgatt ctgcaatcca taaaccaaaa ttattgattc
     2761 cagcctgtac gtttggccac accacagcaa gaatcaatgc cacgattgtt gaccataaga
     2821 taacaacaaa cggaacaaag cgctttccat tgaaaaatga caaagcatcc ggcaattttc
     2881 tataattata gtacttatta taagccattg ccccgacaaa tccagcgatg atccctacga
     2941 atactcccat attcaaagct ggtgcttcca atacacttgt aaaaaatcct ttaaccatga
     3001 tcttcgtacc gaacagagtg tgggtaaatg catcttcatt cgcaagcatg tcacttgtga
     3061 caccaaagat agccccagtg atccgattga ttaaaataaa tgagatccca gctgcaaatg
     3121 ctccgcctgc tctttctttt gcccaacttc ctcctattgc taaagcaaat aaaatatgaa
     3181 gattaccaat aattgcccaa ccaatatttt caattactcc gcccgttgtg acaagcggcg
     3241 tccaatcagg attgatcaag ggaattgatt tccctatact gatcatcaac ccagctgccg
     3301 gcataactgc taccacaacc attaaagcct ttccaaattt ttgccaaaac tcaaaactaa
     3361 atatcttttt cattccgttt agctccttta cgcaatcggt ttcgttaaac gtattatagc
     3421 gtgcgttttc ttttttgtaa atgctttatt ttttattttt ctgtctatac cattctataa
     3481 aacctataat acgtgtgttc ccttctataa ttttctccta aaaatttatt tttttaagct
     3541 tttttctatg aaatattttc ttttgtctat tgacttgtgc aatcggttgc gtttattatg
     3601 aacgtataaa acagctcatt aggaggagaa aaatgaaaca gatcaaacga ctatttgcta
     3661 ttgatccatg gaaaatcagc acgacacaat tagataaaaa aaatcttcga ctgcaagaat
     3721 ctttaacaag tattggaaac ggttatatgg ggatgcgcgg gaactttgaa gaaacttact
     3781 caggggacca ccatcaaggt acttatttgg cgggtgtctg gtatcccgat aagacacgtg
     3841 tcggctggtg gaaaaatggt tatccagaat actttggaaa agtgatcaac gccttgaact
     3901 ttatcgcgat agatatttcg atcaacgatc agctgatcga cttggcttct ttggaaccag
     3961 aagactttta ctgggaatta gatatgaaaa atggtgtatt atctcgtaca ttcacaatca
     4021 ctacttctac taataaagta cgcatttcct tcgaacgttt tctgagcatt gtcaaaaaag
     4081 aatcagctta tatctattta actatagaaa tgcttgaagg tagcggaaca gtcaaactcg
     4141 tatcaaaatt ggatggaaat gttcaaaacg aagacagcaa ctatgatgaa catttttgga
     4201 atgagattga tcgtggaact atagaagaaa tcggctattt gacgactaaa actattccaa
     4261 acaactttgg gattgaacaa tttactgtta ctgcagcaat gcgccatttc gttaatggaa
     4321 aatcagtcat ccctgactat cacgaagata ctttagcatt acatggttgc ttgtctgcag
     4381 aattatctca aggtgagaca tggtcagtgg aaaaagaaat tatcgttctt actagtagag
     4441 atattccaga agcgcagcaa gcagaaaaag ctgtctcaga attaacgaac cagacaaaca
     4501 attatatcca agcaaaagaa gagcaaacag cggcttgggc agaacgatgg aagcttgccg
     4561 atgtggtcat cgaaggagac gaagaagcac aacaaggtat tcgattcaat ttgttccaac
     4621 tattctctac ttactacggc gaagatgaac gattgaatat cggccccaaa ggattcacag
     4681 gagaaaaata cggcggagcc acttactggg atacagaagc gtatgctgtc cctctttatc
     4741 ttgctttagc caaacctgaa gtaactaaga atctgctgaa atatcggcat aatcaactgc
     4801 cgcaagcaat ccacaacgct cagcaacaag gattaaaagg cgcgctttat cctatggtca
     4861 ccttcactgg tgtcgaatgc cataacgagt gggaaatcac attcgaggag attcaccgaa
     4921 atggcgcgat tgcctatgca atctacaatt atacgaatta caccggcgat acggaatatt
     4981 tgaaaaatga aggactggaa gttttagcag aaatcgcacg cttctgggca gaccgtgtcc
     5041 atttttcaaa acgagcaaat aaatacatga tccacggtgt gaccggccca aacgaatatg
     5101 agaacaatat caataacaat tggtatacaa atacgatcgc agcttgggtc ttgcgttaca
     5161 cgcgagaaaa ttatttaact tatcaaaaag aagctgctat cactatcagc gaagaagaac
     5221 tagccaaatg gaaagatatc gcagagaaca tgtacttccc agttgacgaa gaattaggaa
     5281 tctttgtcca gcatgacaca ttcttagata aagatctcat gcctgtatcc gatattccca
     5341 caagcgatct tcctctgaat cagcattggt cttgggacaa aatccttaga tcttgcttca
     5401 tcaagcaggc agatgtacta caggggattt atttcttcaa tgatactttt acaaaagaag
     5461 aaaagcaaaa aaactttgat ttctatgaac caatgactgt ccatgagtct tccctttcgc
     5521 caagtatcca ttcgatttta gcagcagaat taggaatgga aagcaaagct gtagaaatgt
     5581 accagcgaac agctcgcttg gatttggata attacaataa cgacacagaa gacggcttgc
     5641 acatcacttc catgactggt agctggttgt cgattgtcca aggatttgct caaatgaaaa
     5701 ctgcccatga tcagttgaga ttcgcaccat ttctgccaaa aacttggaaa gcttattctt
     5761 tccatatcaa ttatcgcgga cgtttattgt tcatctcagt cacagatgaa caagttactt
     5821 tcgagttatt agaaggttct cctctagaaa tttacgtcta tgaacagtct tattctttag
     5881 cggatcgtct agaaataacg ctaagaaagg aggaagcaaa tgtttaaagg ggtattgttt
     5941 gatttagacg gtgtcattac cgatactgct gaattccatt atcgtgcttg gcgaaagctt
     6001 ggtcaggaaa tcggcattac gatcgaccac acattcaacg aacagctaaa aggcgtcagc
     6061 cgagaagact cactctcttt gcttttagct tatggcggaa aagaacactc tttttcaaag
     6121 gaagaatttg cagaattagc gaaaagaaaa aacgattatt atttagagat gatccagacg
     6181 atcgaaccaa aagatgtctt ccccggggtc gtgcctttac tggattcttt aaaagaagaa
     6241 aaaatcaaga ttgctcttgc ttctgcaagt aaaaacgggc cattcctact tgaaaaaatg
     6301 ggtcttacac cttactttga tgctattgcc gacccggcag aagcaacaaa cggaaaacct
     6361 gcgccagata tcttcctcct tgcagcaaaa gctgtcggac taaaagcaga agaatgtatc
     6421 gggatcgaag acgcgcaagc cggtatccaa gccatcctct caagtggcgc tcaaccaatt
     6481 ggcgtgggac gtgctgaaga ccttggagag gagatcccgc ttgtccctga tacgactttt
     6541 cttacgatcg attacttgaa agaaaagtgg catgaccatg gataatccag agatctccgt
     6601 cgtaccagtt ccagagactg aaataaagaa aatcacattg aagaacgact acttagaagt
     6661 cgttcttctc aattacggtg cccgcctgca ccaaatcttc gcaccagaca aagaaggaaa
     6721 atcagaaaat gttttattgt cttacgatcg tttcgaagat gttctaacag acaaaagctt
     6781 ttttggagca actgtcggac ctgtagccgg aaggatccgg gatgcttctt ggggtgagca
     6841 tagattggag aaaaactgcg gatcacacca tatccacggt ggcacgaaag gctggtcttt
     6901 ccaattttgg gaagtagaag ttttcaaaac tccatcatca ataggtgtgg tcttttactt
     6961 aaaagatgaa ttttctacct atccaggacc aatcactgct acgatcactt accgtttaac
     7021 aaaaaacgaa ttagagatga caacctctgc tagtagcctt gttgaaacca tctgcaatcc
     7081 gaccaaccat gcctacttca acctttcagg aaatggaaca agagacatct atgaacatca
     7141 gttaacggtc tttttagatg gtgtgcttga attagatcaa gaaaaactgc ctactggaaa
     7201 ttggacaaaa aaagaaaaac tgccaatcga ctttagaaaa tccccaacac tgcaagagat
     7261 ccttgcatgt tatccagatg gactagatga tgtatttctt ttgcatcatc ctaggctttc
     7321 caaaacttcc ttacaattat tcgagaagca ttctggtcgc caaatgacta tagcaacttc
     7381 taataaaagt atggtattat tttctacgac tggattcgaa gctgatttct ctgtcaatgg
     7441 aaaacagatg cattcaaact acggattagc aatcgaaccg caagaaatcc ctgatatcgt
     7501 tcatttcccc aaatttggat cgatcaacct ccatcctggt caagaacgga tcagtcagac
     7561 gatttatcgg ttctctgcac aataacaaga gaaaggtgtt tttatcatgg ctattaccgt
     7621 aaaagatgtg gcgaaaaaag ccggtgttgc cacctcgacc gtctctcgtg tcatcaacga
     7681 tcatcctagt atttccgaga caacaaagaa gaaagtccga aaaattatgg atgaactagg
     7741 ttatgttcct aacatgactg cccgcaatct aggaaaacgc atttccagtg ccatcggcgt
     7801 aatcttaccc cctcttgatt caaaagagcg gatcggtaac ccattttatc ttgagatcat
     7861 ggaagcaatc aacgaagaag cgcggaatta tgatatgact acagcaatcg ctactgctaa
     7921 aaattttgaa ttgctgttag agaacgtcca gcgtatgcat ttacaaaaac aagtagatgg
     7981 ttttattcta gtgtattcag atagtcaaga tactgtcatt gattatttat accaaaacca
     8041 catccctttc actttgatcg gacagcctta tcatcatgag aacgaaatcg tttatgtaga
     8101 taatgataac cagcttctag gtaaacaagc aacagaattt ttgatccaga atggacataa
     8161 gaatatcctg tttgtgacaa acacgactca tgaaagtttg tatttcgaac gatatttcgg
     8221 ttatcaaaaa gcaatgatga tggctggtct tcctgcgtta tccagtgtag tactagagca
     8281 tccggaggat tatctgtcct ttgagaaaac gttgaaagaa aacgaagcca cagcattggt
     8341 ggtcattgac gatatcttcg cccttcgcac gatgcagttg gcgcaaatgt atggctatgt
     8401 cattccagag acactctccg tcattagctt caacaactcg atcttctcaa cattaacaca
     8461 cccttacctt acaagtatcg atatcgatat ctccgaatta ggacgtgtcg ctatgcaaaa
     8521 gctgcgcgaa ttgatccatg aagaattgag cagtggcgta cgtttggtca tccctcatcg
     8581 cttgatcaaa agagagacag tcgttccttt agaaaaccca tactaaatag ctgactcact
     8641 aaatacgctg accatttatc ctatggtcag ctttttatgt aaaagaagat actacttcta
     8701 acacattgtt tatctgtaaa aaagagcgtg ggacaaaagt aaagaacact tttgtctcac
     8761 gctctaaaca cgtataaacg gcggaagcag aagcaactcc ttcggaaata agctgaaatt
     8821 cacaaaaatt taaaaagcaa ttttcttgag tttcttctta tttcttggag ttaaacgctt
     8881 ctgtcccagc ctcttttttc cttccttcaa ttttttacac gtcgacgatt caataaaaaa
     8941 ccgcctaata ttgtaaagac aggtgcaaga atcgagaaaa aggcgaatgg caagtaatgc
     9001 aacgcgctaa ctttcatcgt tcccataatg aatgtgccgc tgactcccca cggtacgaga
     9061 gaattgacgg tcgcacctga atccgctagt gttcgtgtca aataggtttt tgataagcca
     9121 acgtcatcaa aagaacgctt gaatgtttct cctggaagaa tgatggacag atactgttct
     9181 ccaacgatca gattgattcc gatacagctc aaggcagtaa acccgactaa acgagaaggt
     9241 cggtccatct tttcttttaa ttcttgaacg atggtatcaa cgatcagata tttgatcagt
     9301 aacccaccta atgccaatgc aagtaaaatc aaactagcag aacctaacat actcatgatc
     9361 ccgcctcgag aaagcagttc atctagcttt ggatcaggtg tatttgcgac ataaccattc
     9421 atcaagatgt ctgctgcttt tccgaccgtc aaacttttct catggataaa agaaagaacg
     9481 agagcagctg tcgatcccgc tagtaatgta gggatagccg gaattttttt gattgccccc
     9541 ccaaataaaa taactagtgg aatcaatgtc caaggagaga tccaaaagct cgctttcatg
     9601 ttttggatca tttcattgat actagctaga tcggctgaat gactgttatg tcctaatatc
     9661 gtataaaaaa tcaacgaaag gacgaatgct gggaaatccg tataacgcat accagcgata
     9721 tgttcgaata gattaactcc tccaataccc gctgccaagt tggtcgtatc tgataaaggc
     9781 gagcagttat tccctaaaaa ggcaccggaa acgactgcgc ctgtagtcat tgcatcattg
     9841 aatccaagta aatgaccgat ccccaaaaaa gcaattccaa tcgtcgaaat cgttgtaaat
     9901 gaactgccga cagtcactcc gacaattgca caaacaagaa atgctgtcgg taaaaagaaa
     9961 cgcacagaaa caagtttaaa tccataaacc ataatcgtag ggatggttcc agataaaatc
    10021 catgaagcaa ctaagacacc aatcaaaaga aaaatcagga ttggaatgat ccctggagtg
    10081 attcctttga tgatcccgtc atggatctca tcccatgtga actttttaaa tctgccataa
    10141 aacaacaaac acatgaaagc tgcaaggatc gggatatgtg gcgagagctg gaatccgatg
    10201 atcagtactc ctaggagtgc caacaacacg atcaatacag cgatactttc ttttaaagaa
    10261 atatttttat tcatcgtcga tctcctattt caaatgaaaa ggccctgcca tgaaaaaa
//
LOCUS       DADGKS010000086         9994 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.089, whole genome shotgun sequence.
ACCESSION   DADGKS010000086 DADGKS010000000
VERSION     DADGKS010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9994
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.089"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..642)
                     /locus_tag="JXV47_002446"
     CDS             complement(<1..642)
                     /locus_tag="JXV47_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAX1488458.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKE"
     gene            complement(806..1129)
                     /locus_tag="JXV47_002447"
     CDS             complement(806..1129)
                     /locus_tag="JXV47_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAX1488459.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWKTTQPRLRDSLIFLGGSLAIVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEK
                     KESGN"
     gene            1917..5144
                     /gene="fss3"
                     /locus_tag="JXV47_002448"
     CDS             1917..5144
                     /gene="fss3"
                     /locus_tag="JXV47_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HAX1488460.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVALVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            5257..5571
                     /locus_tag="JXV47_002449"
     CDS             5257..5571
                     /locus_tag="JXV47_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAX1488461.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            5584..5958
                     /locus_tag="JXV47_002450"
     CDS             5584..5958
                     /locus_tag="JXV47_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAX1488462.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            5968..6303
                     /locus_tag="JXV47_002451"
     CDS             5968..6303
                     /locus_tag="JXV47_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HAX1488463.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            6386..7726
                     /locus_tag="JXV47_002452"
     CDS             6386..7726
                     /locus_tag="JXV47_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010759325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAX1488464.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            7804..8478
                     /locus_tag="JXV47_002453"
     CDS             7804..8478
                     /locus_tag="JXV47_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAX1488465.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            8711..9145
                     /gene="dcm"
                     /locus_tag="JXV47_002454"
     CDS             8711..9145
                     /gene="dcm"
                     /locus_tag="JXV47_002454"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HAX1488466.1"
                     /translation="MRFLDLFAGIGGFRLGMEQASHHCIGFCEIDKFARRSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQRFSDTRGTLFFEIARF
                     TTLLRPKLLFLENVRGLLNHEGGATFETILRTLDGLGYDVEW"
     gene            9146..9853
                     /locus_tag="JXV47_002455"
     CDS             9146..9853
                     /locus_tag="JXV47_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HAX1488467.1"
                     /translation="MLNSKAYIPQSRERIFLIGHSRDACTEQVFPIIGPSSTSDQNIR
                     NLVNINPSNRGMGGQVYGSDGVAPTLTGDEGIKIALPARDGISVAGLLPGKFEQGNRV
                     YEVTGTAPTLSTKQGGTKIMIRKNETEYQEVKPEDSVNLAFPNSTSRRGRLGKQSVHT
                     LLTGDQQAIVTDQYQIRKLTPRECWRLQGFPDWAFDRDSQVNSDSQLYKQAGNSVTVP
                     VIFDIARRLKELDVHGL"
BASE COUNT         3252 a         1760 c         2137 g         2845 t
ORIGIN      
        1 ttctttgatc aagtgtcctt catgcaaaat accatagtga gtggcgatct gtgacaattc
       61 atctagcaag tggctagaaa gcaagacggt gatgccccgt tcttttacca aacgttggat
      121 gatttctcgc atttctgcca tccctgctgg atccatccca ttcgtcggtt catccaaaat
      181 caaaaattct ggattcgtga tcagtgcatt tgcaatagct aaacgctggc gcatacctaa
      241 agagaaattc tttgctttct ttttccctgt attttccaat cgcatcattt tcagcaggtc
      301 ttcgatttct ctatccgaca caccgccgtt cgctgcttgg atacgtaggt tatctcttgc
      361 agttaattct ggataaagag caggggtttc aatcgattga cccatacgtc gtcttgctgc
      421 ctgcaaatcc gtcgttccaa ataattcgat cgaaccttca tcaatcgaga tcaaacccat
      481 aatagttctc ataaaggtag acttacccgc tccattttcc ccaatcaatc catagatcat
      541 tccacgtttg atttcgattg atactttatc taatgctttg gcagcaccgt attttttggt
      601 tataccagtt gctttcaaga ccgtttcatt tccaaaatcc atacttatcc ttctttctta
      661 ttgatgagtg aagtatagtt gacgggtata aagaaagcag ccagaaatgt ataaagaaag
      721 tgtaaatttt ccaattgaat gtcaaaaaaa acaatcggac aatacgtgtc tttcctatta
      781 tcaggcagtt tgttatacgc ttgtatcagt ttcctgattc tttcttttcg accaaagtcg
      841 tttctctgta ttcctcttca ctgaaaattt ttgcttcttt cagatcaagc ttgagtaatt
      901 ttaccagacc ggttataagg ataactatag caagactccc tcccagaaaa attagactgt
      961 ctcgcagacg tggttgcgtt gtcttccaat caaagagcgc accaaacagt gctaatccaa
     1021 gtggactggc caccatggta atcgttgtta tcgttgacat aagacgtcct tgtatatgcg
     1081 ttggaacttc tcgctgaagc cagaccatat aaaaagcaaa agaaaacatt aatccttaaa
     1141 aacggactta tgaaaaataa tacatgccgt ttgggattta caattagcta ccaaataaga
     1201 ggttatgaca aaagactttt cacaatccct tcttccgaat aaacggtgtt ctcctgccaa
     1261 ctcctcggtc acaagtcaca atatttatca aacatgagaa gcaatttttg taaattcctt
     1321 cttatttctt gaagctgacc acttctgtca caacctcaga agcggataaa taatattgtt
     1381 tgatgatact ttatcttttt cccgtttgtt tatagatcga atgatattat agaccaagaa
     1441 tcctacctat taacatagct aaaaacacaa aaaaggcact ttccaaattg tggaaagtgc
     1501 cagaaaagtt aggattaagg taactgcgct cagcattgct tcgcccagta cgattctcgt
     1561 aactcgtgaa ctcgaacgat aatcgcaatt aacgttttga gaactgtgaa gctttacggg
     1621 ctttcttaag acctggtttt ttcttcgtat cattgaataa gtttgaaaaa ccttgattta
     1681 taaaggtttt cccgtaaata tattttatta tatttgatta aatttgaaat gtttgtgttc
     1741 taaaatgtgt tctaatttaa aggcagtata tttcgtattt tagattaaat ttttaggctc
     1801 attcattctc aaatccattc tattcagtca ataaaaattt taaaaagact ttataaacaa
     1861 agatgttcaa gcgagcatct tatttttttg tgcttaattt gaaaggagaa catttcatgt
     1921 ataaaaaaca aaaaaagaaa ttatgtgtat taactatttt gagtttggct gttcaagcaa
     1981 ttgttggagc aattgctcct acgattactt ttgctgatga aattacccat ccacaaacgg
     2041 taaccgtaga actagattta gcacatcaat atgctgttga aggaactttt agtgatggtc
     2101 gtccaatgtc agaagtcact gttccgcatt atgcagtgta caacggcttt aaacaagata
     2161 ttttctgtat tgaaccagga gtcccgattt acaatgagtt cactcctggc tatgagaaaa
     2221 acccgttacc agatatgtcc gataaagcca aattagtttc cgttttatgg aaaaaagtag
     2281 gtacagatgc agatactcat attgtggcac agaagatgat ctggcaagaa gttaatgggt
     2341 atacccttca ctcaataaaa cgatcagatg gtagtgccgt aaatatcgca gccattgagg
     2401 caaaaataaa tcaagccatt gacgattatc agaagaaacc aaccttccat aatagtacgg
     2461 ctaaaacagt attagggcaa tcgactactg tgacggatac gaataatctg aatttgtcag
     2521 agttcgatga ggttgtggaa aatgccgcaa acattgatta tcgtgtgaat ggtaatcagt
     2581 tgataatcac cccaaatgcc aattcaaaag aaagtggtgt gctgacgctt aagaaatctg
     2641 ctggtaccgg aacacctgtc gcctataaaa aggctggcca acagacttta atggccgggg
     2701 cgattgataa acctaatacc tacacaatca aaattgatgt ggaaacggag ggttctttaa
     2761 agatcaaaaa agtcgataaa gaatcgggtg atgttgtacc aggaacggtt ttccatttag
     2821 actttggaaa aactttacct gcaaaagacg tgactactga caaagaaggc attgctacat
     2881 tggatgagat tcctcatggt acaaaagtaa ccattaccga aaaatcagta ccggcgcctt
     2941 atacgattga taccaccccc atgactacca ccattaaagc aggcgaaacc atttacgtga
     3001 cttcaaaaaa cgcacgggaa aaagggcaaa tcattctgga taaaagcgga gttgaaacag
     3061 ggagtgatct ttggaatgac aattattcct tagctggtaa tacgtttgcc attcgcaaag
     3121 acagtccaac cggtgaaatc gttcaagaaa tgaccacgga tgaaaacggt catgcggaaa
     3181 caccaaaaga gattgctaat gcgttggaat tgggaaccta ttatgtgacc gaaactaaag
     3241 ctagtcatgg gttcgtgaat acgttcaaac ctgtaaaagt cgaattgaag tatgccaatc
     3301 aaaccgtagc ccttgttacc agtaacgtaa aagggcaaaa tcaagaagtc actggcgaaa
     3361 ccactttgac gaaagaagac aaagatactg gggataaagc acaaggtaag gcagtctttg
     3421 agggtgctga atacaccttg tttactgcta aggatggaaa agctgttaaa tggagtgagg
     3481 cttttaaacc agagttagcg aagggaacga aaggttctga tgaaacggtc actttgactt
     3541 tagacgaaaa gaaccaagtt gccgttaaac atttagctat caacgagtat tattggcaag
     3601 aaacaaaagc gcccgaagga tatagccttg atgaaacaaa gtatcctgta tccatcaaaa
     3661 aggtggatga tagcgaaaaa aatgccgtga ttacccgaaa tgttacggca aaagaacaag
     3721 tgattcgctt tggctttgat ttctttaaat ttgctggatc agctgcgggc actaccgaaa
     3781 ctggcttcaa tgatctgacc tttaaagtgt cgccattgga agggaccaat gaaatcacag
     3841 gtgccgaaga tgaagcgacc acagcttata acgagcaatt agggtttgat ggttatggca
     3901 agtttgaaaa tcttccttat ggggattatt tacttgaaga agtagaagcc ccagaaggtt
     3961 ttcaaaagat tacgccatta gaaatccgtt ctacttttaa ggaaaacaaa gaagactttg
     4021 tgaagagtga gtatgtcttt accattaccg aacaagacca aaaacaacca attaaaacgg
     4081 tgaccgttcc ttacgagaag ctgacgaaca aagcattttc tgttagtttg aaccgtttaa
     4141 tgctctatga tttgcctgag gaagaagata gtttaacttc tcttgcgact tggaaagacg
     4201 gaaacaaaga attaacttct ctggattcta ccgagctagt tgataaattg agttacaatc
     4261 tacatgaaat caaagaagac tggtatgtgg tagcgcaagc cattgatgtg gatgcgacaa
     4321 aagctgccca agaaaaagat gaaaaagcca aaccagtggt gattgcagaa acaagcgcaa
     4381 cgttggcgaa caaagagaaa acaggaactt ggaaaattca gcataaatta accgccgaac
     4441 aagttttaaa taaaactatt gtcttattca actatgtgta tgaaaataag gaagcttttg
     4501 aagcaggcga taagccagta gcgaaggatg ttagcttgaa taaccaagcc caaactgtca
     4561 gttgtacagt ggaacaccat gtttctatcc aaacaaaggc ccacctagaa aacggttctc
     4621 agacctttac tcatggtgat gtggtggata tgtttgatga tgtgtcgatt actcatgatg
     4681 tactggatgg ctcaaaagaa gctttcgaaa caattctgta tgctttatta ccggatggta
     4741 caaacaaaga aatttggaaa tctggcaaga ttgattatga agtaaatgat aaagaattca
     4801 ccaaaactgt gcttgcgaaa aaagtagata ccggaaaata tccagaagga accaagttta
     4861 cttttgcgga aatcaattac gataaagatg ggaatatcaa tggaaaacac aatgaagatt
     4921 tgaaagaaaa atctcaaacc ttaacaccaa aagaagttcc aaccatacta agtacgccga
     4981 aacaaccgga aacaccaact gttccaagtg gctctcaaga atctagtccc acagtgaaga
     5041 ccttccctca aaccggggag aaaaattcca atgttttact gttcattggt tttactttga
     5101 tttttgcgac ggcgggctat tatttctgga atcgccggaa ctaaggtgat gagatgatac
     5161 aagtaaatcc taagaaccaa cgtgcgcgac cgcctcctaa aaaagtagtc gcgctatttt
     5221 tgtatccaaa actaacaatg aaaagaggaa aagaagatgg aattgaaatt tgtcgtgcca
     5281 gatatggctg aaacctttgg aaagttaagt tatgccggtg aaggagaaat tataacagaa
     5341 ggatatggac ggaatactac ggtgattggt cgcagttatc atttgtattc cagtaagcaa
     5401 cgggccgatg atattgaggt ggtagtagct gcggaagccg gtgaaaagga ttttgatcaa
     5461 gaccaaccgc taaaagccgt gaatccccat ttggttgcca aaggctatga gattgagaat
     5521 cgtgggttta ctgattacgt gttgtatgtt gatgatttag tgaaagcata ggaggaaaag
     5581 aagatgagat taacagaagg tattgtcgta gattcaggtt taacatttgg gaagttgcgt
     5641 ttttccgcat tacgccgaga agtacggaag caaaatgagg atggaacaat tggtaatgag
     5701 gtaaaagaac gaacctataa tttaaaatcc tctgcacaag ggcgaatgat tcaagttagt
     5761 atcccagcta atgtaccctt acgcgagttt gcttatgatg cagaggtaga gttggtcaat
     5821 ccaatcgtgg ataccgttgc caattatgtt tttcgagaag gaactaccgt taattggttc
     5881 attaaggcgg atgatttagt cttgaagcgg cagccgaatc aaggaaatcc tacgaaccaa
     5941 aatgaaagaa agaaataggt gaagattatg gaaattaatg ttgaacatat tttagattgt
     6001 ctcgatcaat atggaaaagg cgagctgact gaggaacaac tcgttaaagc attaacctct
     6061 gatgaaaaaa tgtttctgat tatacatcaa ggtttacttg gagaaaatag cgacagtgaa
     6121 gaagactctg atgtactaga ctggttagga gaagaagagt ctttctttat agttgtcgaa
     6181 gtaaatgaaa acttatgtcg gcaggcagaa tccattttgg aagaaattgg tgtggagatg
     6241 ccggatgcta ttgaaggctt tttaaatcaa ttggttgaaa cgaaacaact cccctcctcg
     6301 tagcagtaaa tgactagcat aactttttga aattgcctaa tgaaatccta ttgggctttt
     6361 tcgattggag gtggaaacca tcaaaatgta caaaggacat cgcatacgcg caggagatca
     6421 gcacttggtt tatcactttg ttcttggctg gctactcgct ctgttcatcg gttggatgag
     6481 cgtcttttat tttcaagagt ttagacaatt tgatatttct aagctatcac tttctactat
     6541 tgaaatcgtt tggtctataa aagatttagt atgtctgctt ggaagtctcg ctttttcagg
     6601 agctatgata ttgctttata ttcacttttt tcttgatcat tggcgaagct tgtggcatcg
     6661 acaaaagcta gctcggatga ttctagagaa ccattggtat gaagtgaaac aaactcaaag
     6721 tgaaggcttt ttcaaagatt tgaatagtag ccgaaccaga gagactatca gttacttccc
     6781 caaaatctat tatcgaatga aagatggatt actgtctatt cgcgttcaaa tttcacttgg
     6841 gaaataccaa gatcagcttt taaaattgga aaagaagtta gaaagcggac tgtattgtga
     6901 gttagtagaa aaggaactca aagactccta tgtggagtat actttactgt atgatatgat
     6961 cgccaatcga attgggatag acgaagtagt ggcagaaaat gggactctgc gattgatgaa
     7021 aaatcaagta tgggcttatg attctttacc ccatatgtta atcgctggtg gcacgggtgg
     7081 agggaagacc tatttcctcc tcaccattat cgaagcacta ttgaagtcag atgcagaatt
     7141 gtttatcctc gatcccaaaa atgcagattt agctgattta ggtacggtga tgcctcatgt
     7201 ttattcacaa aaggaagaaa tttctgcttg tgtggaagat ttctatgaac gtatgatggc
     7261 tcgtagcaag gcaatgaaag aaatgtctaa ctacaaaaca ggagagaatt atgcctatct
     7321 tggacttcca cccaactttt taatctttga tgaatacgtg gcttatatgg agatgttaac
     7381 gacgaaagaa agtgcggtga ttttgaataa gctcaaacaa atcgtgatgt tgggtcgtca
     7441 atctggtttc tttctgattt tggcttgcca aaggccggat gcgaaatatt taggagacgg
     7501 aatccgcgat caattcaact ttcgcgtggc tttgggtcgt atgagtgaac tcggatattc
     7561 catgatgttt ggggaggtcg aaaaaaactt ctttatgaag cacatcaaag gtcgaggtta
     7621 tgtggataca ggtggcagtg tgattagtga gttttatacg ccacttgtac caaaagggta
     7681 tgatttctta gattcaatta gtaaattaga aaagatgaat gattgagtga tcttcaatac
     7741 tgactttata cttcaagtaa cgtataatac ttttatatag taggaagaaa ggggataatt
     7801 aatatggaaa gtaatgattc ttatttagag tatgcaaaag caaataagga taagtttatt
     7861 tcttatatta tcaaagggaa atcccccgaa gttggacgag acgcagtttt tatggcaggg
     7921 agtcctgggg ctggaaaatc agaggttgcc attggattag ctgagaatta tgataaccat
     7981 gtgattattg atgcggatta ctttcgcacc cagtttcctg attataatgg aaaaaactct
     8041 agtctctttc aaaaagcatc ttcttggttg gtagagcagg catttagata tgtcttagat
     8101 catggctatt cttttattct ggatgcaact tttgcaatat taagtgctga aaaaaatatc
     8161 tcgcgggcgt tgaaaaaaca ttttcgagtg acgattttct atgtttatca agaccctaaa
     8221 atcgcttgga aatttacaca agaacgtgaa attgcagagg gacgtcatgt gccgaaaaag
     8281 gcatttatta acgctttttt caaatcaaga gagaacattg caaaagtaaa gagtaaacat
     8341 ccagatgtat tgcttcatat cataataaaa gattatacga ataatatttc cgaagttcat
     8401 tatgctacgg ataatctaga attattttta ccactagggt atagtaggaa agatttggag
     8461 gttcaattac atgactgaga aagaacaagt aacgaaaatt gtaaagaaat acaataagag
     8521 cattgcggat ttatcggaaa atgctactgc aaaagagttc aaaacggtga ttaaatatgt
     8581 agccgatcag gccaatgaaa aacaacggaa attagttgga ttaaataaaa aatagtagga
     8641 caaattaata atgtatgagc caagagcaaa atgttcttgg cttttttctt tgcaatgaat
     8701 gaggtaatgt atgagatttt tagatttatt cgccggtatt ggtggctttc gtttaggtat
     8761 ggaacaggcg agccatcatt gtatcggttt ttgtgaaatt gataaatttg ctagacgtag
     8821 ttataaagca attcatgata caagtaagga ggtggaaatg catgacatca caagtgtatc
     8881 agatgagttt attcaatccc tcggaccagt ggacatcctt tgcggcggat ttccgtgcca
     8941 agctttttca attgcgggaa agcggcaaag attttccgat actcgaggta ctttattctt
     9001 tgaaatcgct cggttcacca ctcttctccg acctaagctt ttattccttg agaacgtccg
     9061 aggattgctc aatcacgaag gaggggctac gttcgagacg atcctccgaa cgctggatgg
     9121 attggggtat gacgtggagt ggtaggtgct taactcaaag gcctacattc cccaaagccg
     9181 ggagcggata ttccttatcg gacattctcg agacgcatgt accgaacaag tatttcctat
     9241 cattggaccg tcttcaacat ctgatcaaaa catcagaaat ttggtaaata tcaatccttc
     9301 caatcgagga atggggggac aagtctatgg ttcagatggc gtagcgccaa ccttaacagg
     9361 tgatgaagga atcaaaatcg cactgccagc aagggatgga atctctgtag caggactatt
     9421 accgggaaag tttgaacaag gtaatcgagt ttatgaagtt actggaaccg cccccacctt
     9481 gtcaacgaaa caaggtggta caaaaatcat gattcgaaaa aatgaaacag aatatcaaga
     9541 ggtgaagcca gaagacagtg tgaatctggc ttttcctaat tccacaagtc gccgaggtcg
     9601 tctgggaaaa cagagtgttc ataccttact aacaggagac caacaagcga tcgtcacgga
     9661 tcagtatcaa attcggaagc taacacctag agagtgttgg cgacttcagg gctttcccga
     9721 ttgggctttt gatcgagatt ctcaagtcaa ttcagatagt cagttgtata agcaagccgg
     9781 aaactctgta acagttccgg tcatttttga tattgccaga agattaaaag agttggatgt
     9841 acatggttta tgatgagttg attggagaaa tttattgggt gattggaaag attcagtcag
     9901 acccagaatt agaagaacaa ttgcgacggt taaaatttga tattcgcaag aatggtgtca
     9961 aagtcgctgg cgatccatat ttaatgaatg agga
//
LOCUS       DADGKS010000087         9766 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.090, whole genome shotgun sequence.
ACCESSION   DADGKS010000087 DADGKS010000000
VERSION     DADGKS010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9766
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.090"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(354..1556)
                     /locus_tag="JXV47_002456"
     CDS             complement(354..1556)
                     /locus_tag="JXV47_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAX1488468.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            1673..2188
                     /locus_tag="JXV47_002457"
     CDS             1673..2188
                     /locus_tag="JXV47_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAX1488469.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(2387..2833)
                     /locus_tag="JXV47_002458"
     CDS             complement(2387..2833)
                     /locus_tag="JXV47_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAX1488470.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(2880..4358)
                     /gene="msr"
                     /locus_tag="JXV47_002459"
     CDS             complement(2880..4358)
                     /gene="msr"
                     /locus_tag="JXV47_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAX1488471.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(4712..5341)
                     /locus_tag="JXV47_002460"
     CDS             complement(4712..5341)
                     /locus_tag="JXV47_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAX1488472.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(5325..5789)
                     /locus_tag="JXV47_002461"
     CDS             complement(5325..5789)
                     /locus_tag="JXV47_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAX1488473.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(6276..7544)
                     /locus_tag="JXV47_002462"
     CDS             complement(6276..7544)
                     /locus_tag="JXV47_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase"
                     /protein_id="HAX1488474.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(7775..8512)
                     /locus_tag="JXV47_002463"
     CDS             complement(7775..8512)
                     /locus_tag="JXV47_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAX1488475.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(8579..9148)
                     /locus_tag="JXV47_002464"
     CDS             complement(8579..9148)
                     /locus_tag="JXV47_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HAX1488476.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            9276..>9766
                     /locus_tag="JXV47_002465"
     CDS             9276..>9766
                     /locus_tag="JXV47_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAX1488477.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDR"
BASE COUNT         2910 a         2031 c         1715 g         3110 t
ORIGIN      
        1 cagctgaccc tcggtattag ctcaaaaaac ggtaaaatat gagaagctat ttttccgttt
       61 tgtttctcta atacttagga taaaacgctg attttacaac ctctgttaaa cggtgttcaa
      121 tcagctgtcc ttcggtatta gctcaaaaaa cggcaaaata tgaggaacta tttttccgtt
      181 tgtttctcta atactcagga caaaacgctg attttacaac ctcctgataa acggtgttca
      241 aaagcttgca tctgcggtaa taagcccaac caaacgaaaa atatgagaag ctatttttgt
      301 ttggctgttc ttatgacttg atgcaggaca gctttttcac aacctctgat ttcttattct
      361 tcttcatttg tagcaaaata attacggtga taaatgatac aacatacact gataagaaca
      421 atggcacctg caaaataaaa cgcatagctt tcaccaatat gttcaccaat cacacctgca
      481 ataaatggtg ctaaagctcc accgaaaaag cggacaaaac tatagctgga cgaagcaacg
      541 tttcgttgca gacctggtat ttccatagca atcgtcgtca acagtgtatt gataattcct
      601 tggaaaaatc ctgctaacac aatgctgatc ggtacaagga ctggcataga agttccagct
      661 cctaataaca gcaaacaaat aatgaataag acaaatgctg ctaaaattgt ccgataagtc
      721 gtaaacttcc gctcaagagc cggtgcaacg aaaatcgaag caatagccag aagcacaccc
      781 cagccaaaaa atacaaaacc gacttctaat tcagaatagc caatcaataa aaatggcgca
      841 tacgcaagta aagtaaagaa tccgaaatta tataacaatg cgattagtcc aactgaacga
      901 agtttatgat tgcttaacgc tttgacacct tcccaaaggc ctacttttct ctttggtttc
      961 tcagtttcag gtaaaagtac cgctagggct ataaaaccgc aaaacatcaa aaatgctacc
     1021 ccaaaaaatg gataacgcca tgaaccactg cccaagaccc caccgactag agggccaaca
     1081 gccattccgc agccaagtgc tgcttcatac atcatgattg ctttttctgt gttaccaact
     1141 aaaatactga cgatcgttgc taaagcagta gagacaaata aagcattccc gacaccccag
     1201 ccggcacgta acccaatcag cattccgata ttcccagata atccgccaag accagcgaat
     1261 acaacgatga taaacaatcc tgtcatcaat gtttttttca aaccgatccg actagataag
     1321 aaacctgtaa atagcatcac cacaccagtg actaacatgt aactagtaaa taacagggtc
     1381 gtttcagctg gcgtagcgtt taactgtgca gcaatcgttt ttaagattgg gtctactaga
     1441 cccactccca taaaagcgat catacaggta gctgctacaa ctagcgctga acttttcccc
     1501 tttgtttctt catttgtttg ttcttgtata tctatttgat tctccaatat ttccatccct
     1561 ttctctctat tagcatcata catgatttat tttacatgtc aatatgcaca tgtaaaacgt
     1621 ggaaacttta ctgtgatata ataaagaaaa taagacgaga ggtaggattt ttatgaatac
     1681 tttagcctat atattattat gcgtgctttt atccaaacca cgttctgggt atgaattgaa
     1741 gcagctgatc acaatttttt gggaagccca tcacagtcag atctatacaa cgcttgccaa
     1801 gttagaccag cagggttatg tgaccgtttt ggacaaagac gagcactctc aaaaaaagat
     1861 ctaccacttg actgatgaag gacgtgctct tgtagaggaa tggatcaaag aggaaactcc
     1921 cgctcctacg caaaaagatg aatttctagc aaaaatctat gctttttcga cgctcgataa
     1981 aacaacagct actggactgc tattcactag agaacaacag ctgaacaaaa tcatgcaaaa
     2041 aaatcaaaaa aaattgaatg acctctcgct agacaagaaa caagaatttg gacgttatgt
     2101 tgtgatccag cgcagaatta tgctttgtca gcaggaactc caatggtgtc agcaagtaag
     2161 agaacaaatg cagcagtttt ttgagtaagg gataaacaga acctttctag aaatatctat
     2221 tgaagagcaa attatcttca ataaaagagc aatacagttg gaaaagaaaa agcgatccga
     2281 acgacaggcc aaaacctatc gttcggatca ctatttttct agaactgcat tcaagagact
     2341 atgacaaaaa gcatgccaag gccttttttc aaataacagt gttccatcat tcattacttt
     2401 gaattgcttt tagcacactt cttgaaagcg ggccaacgat gatcaactgc aacggtaaag
     2461 cggcaatcac attcattttc caagcattca tataagcaga gaataattga tcaggtattc
     2521 cttgttccat gatcacaccg aataaagaca tacatgtcac cattcctaaa accatcaagc
     2581 atgaaatagt taagatcatt tggaccttgc tttctggatt tactggtagt ttaaaggcaa
     2641 tttttttcgc cagcacaccg atgatgaaga catccaaaat gaaagccacc acgaatccag
     2701 gcactagacc aatcaacaaa cttgataaat gaagatcttg atgcagccat aaattatacg
     2761 cgctcatccc caagaccatc aaaaaacaca tcattgttgt aaaaattatt ccttcttttt
     2821 tatttgtagg caatctgtac cactccttta aatttgtcac gaaaatcatc gtagcacatt
     2881 taaaaatttc tcgtaagtac tttttttatt ttctgccctt ttatttcata aacttcatca
     2941 gccgtacgct cgacaaagta agaatcatga gaagtaaaca aaatcgttcc cggatatatt
     3001 tgcattagct tctctaaagc ttcgatcgtt gccatatcaa taaaattagt cggttcatct
     3061 aacagcaaca cattacttgg cttagtaaaa agcaaagcaa tcgtcagacg ggtcgcttct
     3121 cccccactta atgtacataa cggtttcgtc aaagtttcct gagcaaaccc taagtgattc
     3181 agcaaactac ggacaagcga ttctgaaaac tctgtttgtc tcatgacaaa acgaatgatg
     3241 gattcttcag atgtcatttg ataacccttt tgctgatata cttgaaagct tactttcgga
     3301 gagagaagga ttccttctcc ttgtttgcgg atatgttcta ataaggttgt cttacctgaa
     3361 ccattttcac cgacaatcgc gattttttta cctaaagaaa actgaaaatc accatttacc
     3421 agtaatgttc tcccacttct ttccaattgg acattttgtc ccatgatggg atagcggctg
     3481 tggagttcaa gagattttgg tactggaaaa cggatttgtt tcatctgctg cggcttggtt
     3541 gtttctccta ttttttggag tcttctctct aatgttttcg cattcttttg gatggctttt
     3601 tgtacactgt ctttttgttt agaggaagac aaccgatccg gtctgatttg ttgctttttc
     3661 tttttactgg acactttttc caacttttcc gcttgttttt tcttttcttg gatcgatttt
     3721 tccaatcgtt ttttctcttt catgatcgac tctgcttctc gtagctgagt ctttttctcc
     3781 aattcctttt gagtgagata ggcactataa ttccccgaaa actctcggat ttctccgtct
     3841 tttacttccc agattttcga tgctagctca tctagaaaat agcgatcatg actaacaaaa
     3901 accagcgtac cataataata acgaagctct tcaatcagtc gatcaatact ttttctatct
     3961 agatgggttg ttggctcgtc tagaagcatc ccttgttcat aagaagaaag aagacgtatc
     4021 aactcgatct ttcgttcttc ccctccgctc catttccgct ctgaagtttc ttccagtctt
     4081 aactggaaat gactggctaa ttccaaattt aggtcctttg cttcagcgag ataggttaat
     4141 tgaggcaggt agttgaaggt gatctctgtt tggattttcc catgatcggg aaaaagttca
     4201 ccggctatta gtttgagcaa agtcgattta ccgacaccat tttctcctat gatccctata
     4261 cgatcttgct gatagacacg aagagaatca atagatagtt ctagctggtt gccaaagctg
     4321 acttgtagat ttgttatatt tactgctaaa ttttccatat gttttacact cctatttcat
     4381 gtaaaacaac aattatcgat actaaaaaag agcagaaaaa tctgtttgca aaaaaactgc
     4441 atcacatctt ttcctactct gaacgaaata actatgacta aatcaccaaa tctgtcatag
     4501 ctttcaccta ttctactgtc gttcgaaaaa atggacatac tccatccatg aaattgttgt
     4561 ttatacatgt cttttgaatt tatttagttg ttattcaaaa gttcgaaacg taatttcatc
     4621 gatgcagtca tttttccgac ctcctttttt attaggttac cacacacgat tcaaaaaaag
     4681 caatagctac tgaatagtaa ctgaaaacct tttattcgaa cgtagtgatc ttttctggtg
     4741 ctaaacgaac agactcgtaa ccttcttcta ccgcttttcc tattgataaa ataataactg
     4801 gaacataacg gtctttatcc aaaccaaatg cctctgccaa ctgatctgct tcgaatccac
     4861 caattggatt tgtttcatag ccatgatcac gcgcaactaa catgaattgc atagccgcta
     4921 agctagaatc gactttgact acatcgttca tttcttctct tgaaaaactc ttgtaataag
     4981 gaatgatcgc agctaattgt tgatctctga cttcttttgg catcttccct gattcgtaag
     5041 cttggttgta gatttcttcg ccatattcgt aacattgcat atcgccaaaa atcatgacca
     5101 ttgcagaaga agtatcattt tgtctcgtat tgaaacggat caaaggacgc aagatttctt
     5161 ttgcttcctc gctttcagcg accacaaagc gccatggttg catattgaca gaagaaggtg
     5221 cagtcgtcgc ttctttgatc atttccagca tttcttcgtg tgggattttg tatgtttcat
     5281 catatacgcg aacggatctt ctaccagtca taattgttga aaaatcattt ttttgttcca
     5341 ttattattaa cctctttcgt ttctgttgtt atattgcaaa gttgggtatt caatttatct
     5401 aaaagtgtta gaaattgttt catttctaca tcgctgaaag ccggggatag cacggaacct
     5461 gtatctttat ggtccatttc acaatgctcg attttcttct gggctttttc tgttagcgct
     5521 acatacactt cccggttgtt ctgaggattt ctctgacgcg aaacatagcc atttgcttcc
     5581 aataccttca gatgacgagt aactgctcct tgatcaatct gcaacttttc ttgcaaactg
     5641 ctttgtagca atggattttc ttctttcagt ctcatcatga tctcgtatct agtaagactt
     5701 ataccgatat tttcttcaaa gatctggacg attttttgat cggctaattt gatttgatat
     5761 aaaaggtgac taatctcttc taaagacata atttcctcct ttctaataat tgactcgtca
     5821 acgattgact tgtcaataat agaataaaaa aagaaaaaag tcaaagaatc agctgtgtaa
     5881 taaaaaaaac gctctcaata gaaaagtata gagaaaagaa attttttgta gaatgaacgg
     5941 aaaaaatgat aaagaaagca caacgctaaa accaagatta ttgattctta tcaaactata
     6001 gaagatagct cttctgcagt agaaaatttt acaccgccaa aaatttccga aatcgccttt
     6061 tgcaagaatc ccgtcgaata ttagaaattg gatcagtatg cttaaacagt aataaaaaag
     6121 ttatgacaag atgttgtcac aacctttttt gagtaaacgg tgttcaaaaa cttgcatctg
     6181 cggtaataag ttcaaccaaa caaaaaacat gaaaatctgt ttttgtttgg ctgttcttac
     6241 tacttgatgc agggcagctt tttcactacc tctttttaat aaccataaaa tcctattcct
     6301 tcatatctcc agcccatcgg tgttagccaa tctctttcct tagcactcaa ggtatagtga
     6361 tgggtaccag ttttttcatt tggattaaat agtcgataaa ttggcttgga accaccagaa
     6421 taaaaactta gaccttcata acgccaaccg atttttgtta aagagttgat ctcagattgt
     6481 gccattgtgt aatgatggtc tccactgtaa ggattgtata aacggtagac aggttgtccg
     6541 ctgtttggtg cttgccaagc aatcccttca tattcccagc ctacagttgg cagataattt
     6601 ttttctccgg cattcaatgt atataaatgt tctcctgtat gacggttata cagacgatac
     6661 atcggagaag ttgaagttgg tgctgtatca tactgtgtca gattataggt ttcgattaca
     6721 ttgttcaatg tagaaccata attaggcgca gtggcataac gacctgttag ccaagccgta
     6781 gcatctttgt aagagttcgt attgcttttc catgcaccgg aatagtagta aacgcctggc
     6841 tgaaaagaag tcgtcttcaa taccgttacg ttatcttgca atgattcttt gtacgaagga
     6901 tattttctaa aagcggcatt caccgtaatc cattgcccat tcacatattc cgaagtaggc
     6961 atcgtaacag attggccatt atagcttcct ttaatcccaa atagattgta attaggggca
     7021 gaagccaaag tactgttccc ccagccactt tcaacgatgg cttgagcaat catgactgat
     7081 gcatataagt cattggcact tgccaaactt tgtgcagttg aggcaatact atcaatgaac
     7141 gcttgttgag aattagcaga tgagcgagca taaaaagcat agccagtata gttttcgaat
     7201 tcagacaaat ctgcttgatg ggtatgtgtc aatgtttgcc catctgtcaa ttggttcgtg
     7261 atttcttctg cattctctgg attgttctga gcttctgctg atgtactgtc ttcggtttgt
     7321 gtttgttctg ttgtttcagt tgttggttct tcggttgaaa ttgtattttc tgagacagta
     7381 gctgactgca aagtactttc tgtatcgttt tcaattcctg tttctgaaga actcgatgtc
     7441 tgagttgcga cagtttctgt cgattcttca gctagcactg ttgtgttggc aactgctaga
     7501 tttcctaaaa gaataacgct aaataataaa ttctttgctt tcatcttttt tctcctttga
     7561 attatgaaac ttttcctaaa taacagtgta actaaaaaag taaaagcaag tcaatgtcca
     7621 tatttaaata acatttgttt ctttttaata aatttgcttt ttctgcataa aaagacgtaa
     7681 atgaagaata ttcttctcca ttcacgcctt aaattgatgg tcgtttgaat aactatttaa
     7741 caagtaattc tctctggata ttatccgtta tggattatac ttcctgtgtc gtcggacgga
     7801 taatcatgtt gctgacagac atccggtctg gcgtttctat cgcaaatgct acagcagaag
     7861 ctatatcttc agatgttaat ccccattctt tttgcgcttc atgaagttca agagcagcct
     7921 ttttgtcgct gatggtttga tataattcag tttgaacagc tcctggagag atgatcgtag
     7981 atttgatgtt attttgccgt tgctcttgac gtaatccttc catgattgca cggacagcaa
     8041 attttgttcc gcaataaacg gcggaatcag gataaacaac atgtcccgcc acagaatcag
     8101 ttgaaatgat atgcccagat ttttgttttt ccatgattgg aagtacggcg gaaattccat
     8161 ttaacacacc catgatgttg atatcaagca tattttgcca ttcatcacgg tgaccttcaa
     8221 ctaatggagc ggttggcatg attcctgcat tattgtacaa tacatcgatt cgaccgaact
     8281 tttccatcgc taaatcgata actgcttgga cttgtgcaaa atctcttaca tctgctgttt
     8341 gaatatatag ctcagcttct ggtaaagatt cttttattgc ttttaggcga tcttctcggc
     8401 gtgcagctat aactagttta gccccttttt ctgctaatag cttcgttgtt gcttcaccga
     8461 ttccgcttga agcgcccatg atgacaatca ctttttctga taaatcattc attctattct
     8521 cctcctgttt tgaaaaatct cttgcttata ctcactatct cttatttcat cttactgttc
     8581 aaataatccg ttcgacaggt ttgacgattt tggcagggat tcctgcaacg atggtattgt
     8641 ctgggacatc tttcgtaaca gttgcattcg ctgcaacaat ggcattctcg ccaatcgtta
     8701 cgcctggcag aatagttgct cctgctccga tccaagcatt tttcttgatg tggattggct
     8761 ttactgacaa gcctcttcgt tcttttggat cggttagatg gttcaccgtg atgaggttga
     8821 cacgaggacc aatcaatact gaatcttcta aacagatgcc acctaagtca acgaacatca
     8881 cttgacgatt gataaagaca tttttcccta tactaatatg tttgccgaaa tctgtataaa
     8941 aaggcagcag aacagtcacc gtatcatcta ctttgtcact aatgatattt tctagccgtt
     9001 tgcggatatc tgctggttca tggtacccag tattcagcgc tgctaaaggc tcttcgtttt
     9061 ccgcttggat ctgatggatc acttcaaaga gcggatccgt tactcgaatc tctttattga
     9121 cgatttgttt ttcgatgagg cttgtcattt tgctccctcc ttttatcctt actttataac
     9181 ggacggctta tgatgtctaa tacttataaa acatacttaa ctattccttt taactatact
     9241 tagtggtatg cttttttaaa aacaggaggg aaaaaatgga tattcgtata ctgacgtatt
     9301 ttttagcagt agctagagaa aaaaatatca gccgagcagc aaaatctctg catatcacgc
     9361 aacctactct ctcaaaacaa ctgaaagatt tagaagaaga acttggtgtg acacttttca
     9421 ctcgaggctc ccgagagata cagttgacgg attctggtcg atatctttat tcaaaaggaa
     9481 aagaaatctt gtcgttggta gaaaaaacgg cgaacaattt aacaaatgac gcaatcatct
     9541 ctggagaaat ctacattggc ggaggcgaaa ctaaagcaat ctctttcatt tctgatagcc
     9601 ttcattcgtt gatcaaggcg catcctgata tccagtttca tttatatagc gggaatgcag
     9661 atgatatcat agacaaactg gatagcggat tacttgattt tggactcgta atcgaaccga
     9721 caaacaaaca aaaataccag tcatttcgac tgccagccca agatcg
//
LOCUS       DADGKS010000088         9551 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.091, whole genome shotgun sequence.
ACCESSION   DADGKS010000088 DADGKS010000000
VERSION     DADGKS010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9551
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.091"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            1..417
                     /locus_tag="JXV47_002466"
                     /pseudo
     CDS             1..417
                     /locus_tag="JXV47_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            complement(325..1041)
                     /locus_tag="JXV47_002467"
     CDS             complement(325..1041)
                     /locus_tag="JXV47_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HAX1488478.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(1091..1300)
                     /locus_tag="JXV47_002468"
     CDS             complement(1091..1300)
                     /locus_tag="JXV47_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488479.1"
                     /translation="MDVLREYSSLFTEAYLLEQFGYKIPFADYQQGVGTAAELSFYEG
                     ISQAVGRPVDAEHFEQRISSTGKSE"
     gene            1577..2850
                     /locus_tag="JXV47_002469"
                     /pseudo
     CDS             1577..2850
                     /locus_tag="JXV47_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(2957..3988)
                     /locus_tag="JXV47_002470"
     CDS             complement(2957..3988)
                     /locus_tag="JXV47_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1488480.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(3995..4825)
                     /locus_tag="JXV47_002471"
     CDS             complement(3995..4825)
                     /locus_tag="JXV47_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1488481.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(4822..5628)
                     /locus_tag="JXV47_002472"
     CDS             complement(4822..5628)
                     /locus_tag="JXV47_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAX1488482.1"
                     /translation="MKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLANYS
                     DIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLAANF
                     AGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYPSMK
                     EVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALTSSN
                     VNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(5634..6458)
                     /locus_tag="JXV47_002473"
     CDS             complement(5634..6458)
                     /locus_tag="JXV47_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphatase"
                     /protein_id="HAX1488483.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(6448..7548)
                     /locus_tag="JXV47_002474"
     CDS             complement(6448..7548)
                     /locus_tag="JXV47_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAX1488484.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            7726..8511
                     /locus_tag="JXV47_002475"
     CDS             7726..8511
                     /locus_tag="JXV47_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HAX1488485.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            8544..8927
                     /locus_tag="JXV47_002476"
     CDS             8544..8927
                     /locus_tag="JXV47_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAX1488486.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            9003..9134
                     /locus_tag="JXV47_002477"
     CDS             9003..9134
                     /locus_tag="JXV47_002477"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAX1488487.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            9103..9339
                     /locus_tag="JXV47_002478"
     CDS             9103..9339
                     /locus_tag="JXV47_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAX1488488.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            9351..9518
                     /locus_tag="JXV47_002479"
     CDS             9351..9518
                     /locus_tag="JXV47_002479"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488489.1"
                     /translation="MELGGLPELDGRYTVFGQVYQGLEIVAAIAAQPTNSEDVPIEPV
                     FIRQINFEKTS"
BASE COUNT         2796 a         2267 c         1850 g         2638 t
ORIGIN      
        1 gttccatgag ttttatttgt gttgatggga caacccatca gctatttacg atccttgaag
       61 atcgcagact ttacaaacta actcaatact tcctgcactt tcctagaaaa gcccgtttaa
      121 aggtcaagta cctagaatgc cagctattgt cagctgctta aaacggtctt tccaaatgcg
      181 gagatcgtaa ctgatcgctt tcatattgtc caacatatca atcgcagctt caatcaattg
      241 cgtatccaga tcatgaatcg ttttcgagcc tcgcactctg aaaatcagaa gaagtaccgt
      301 cggctcaagc gatattggaa actcttactc aaagattcca cgacattgga gccgctcaaa
      361 cggcattatc atcgactgtt taaacgacca attagtcaaa cagaaatcgt cgatgaaccg
      421 ttgtgcacaa tggtgtcctg aacgtacagc gacaccttcc atatccagag cagtcgccac
      481 atcacgggga tggatgccat ccaaattaaa agcaaccacg ccagtatgat gttcaggatc
      541 ttgcggtccg taaatggtga taccgccgat cgcttgtaat ttaggtaaaa cgtaggcaac
      601 cagttcttgc tcataacgat gaatattctc cataccaatc tcattcaagt aatcgattgc
      661 tcctgcaatg ttcggagtac cagcttcaaa tttccatggc agctctttcc atgaactatc
      721 gtaaagattg acaaaatcta tcatttcacc gccgaattcg actggctcca tttgttctaa
      781 caattgacgt ttgccatata atacaccgat tcctgtcggc ccgcacattt tatgcccgct
      841 aaaggcgaaa aaatctgcat ccaacgcttg tacatcaact gtcatatgcg gtgctgcttg
      901 ggcaccgact ggactatcct caactacaac agcctgttca accctcagcc gtttcaagca
      961 caacaaataa ccttctggat ctggtttgcc gacctgaaga tcatcgatcg tcacaaagga
     1021 atcaattttt tccttaatca tcggatgtgc ttcaaaaaaa tagtctagct cccgcagttc
     1081 agaattgaga ctactccgat tttccagtgc tgctgatccg ctgctcaaaa tgttcagcat
     1141 ccactggtct cccaaccgct tgacttatcc cttcataaaa ggacagttct gctgccgtcc
     1201 caacaccttg ttgatagtct gcaaaaggaa ttttatagcc gaactgctcc agtaaatagg
     1261 cttcagtaaa tagtgatgaa tactctcgta aaacatccat tcactgtcaa tcatcgtccc
     1321 atcaaaatca aaaataagtg ctttggtcat cttctttccc ccttacccaa aacaagcaaa
     1381 agctgtgtcc tgctctctct acagtatcag cataaaaact gccgtctgaa aagtcaaagg
     1441 tgaaagaaat gtggcgctat aatttctagg actgatagta aatcattcta tcagtccttt
     1501 tgagcataaa aaaacaaaac atacagaagc tccgttagaa ttgaatcacc acaacacaat
     1561 caaaggagcg ttctgtatgc ctgatcttca tcttatcaaa ctattactag gaatcaaaga
     1621 tggaaacatt caaatcactc atgtcgagaa gaaaaaaata cattcaatca acagtatcgt
     1681 tgtttctgcc acgctcatta aaacgattca gccctgtcct cagtgtaaac aggtgaatca
     1741 acatgggctg atcgttaaga acggaaagaa aaaatcgctg gtccttctca ataagtgtgc
     1801 gaatcaacgg acttatcttg ctttggcaaa gcaacggtac ctctgtcgtg gctgtcacac
     1861 ctattttacg gcgaatacct acattgttga aaaaaactgt tttatcgcca aacaagtaca
     1921 ttataaaata ttggaggaat tgactgaaaa acaagcaatg acgacgattt ctaaacattg
     1981 cggcgtttct tggtcaaccg tttcgcgaac actcgcttct ctgctcccca tgacaaacgt
     2041 gaaaataaat tggttgcctc gctgttcatt ggtagatgaa tttcgttcat tgaaaaatca
     2101 agtcggtccc tattcttttt cttgtatgga tggcgatact gggaaattac tggatattct
     2161 tccttcacgt aagaagaaag atctcatttc ttattttatg caatttgaac gacgtgcacg
     2221 tttaaacgta aaaatactcg taacagatat gaacgcctct tatgctttgc tgataaaaga
     2281 gtgctttcct catgccaaac tcgttgtgga tcgctttcac atcgtcaagc acctcattcg
     2341 cagttttaag gatatttgac tatgagtcat gaaaagcttc gaccgaaacg atccaataca
     2401 agccaaacac tatcgacaag tgaaggcttt atctcgactt ctgatcaaac gacaggacac
     2461 gcttgtttat gataaatgga caaaatggcg taattttggt tgggcctatt taaccgaaag
     2521 tgaagtcgta gaacgtctac tttctacttc tgatgaacta cgaatagctt atgcttacta
     2581 tcaagaaatt cttcaagctt tttatgacaa agaagcggac atcttctttc agcttgtaaa
     2641 aacaatgccc aagtcggttc caagagaact gcatcatata aaaaaagcgt ttataaacta
     2701 tgaatccggc attcgtttag ccttagagtt gccttactca aatggcaaaa tagaaaatct
     2761 gcatacccac atcaaagcat tgaaacgaat agcttacggg ttaggatgag aaccagaatt
     2821 ttcttaatca atcatctgat cacttattaa acataaaaaa acatctaaag cagaaaatca
     2881 attctacctt agatgttctt atatcactct atcagtccta tttgacaaag agccagaaat
     2941 gtttgccgac tatacactag ctttgttgtg caaaatgctg agtatcaatt tccacaggga
     3001 ttgctagaat atctttcagc tgaatgtata aggcatcgct aattttctct tcccgatcgt
     3061 tcaaccgatc cactaaaatt tctttgccct ccagcgtttg aaaaacatac cgttgaatgt
     3121 tgcctaaaat aaatgattcc ttccatagaa ccggaatctt aaccccctga ggaaccggtt
     3181 caaattgaat cagctccggt cttaaataat aaatgcagcg attgccctta gcggaaaact
     3241 cgtgggtata ctgattcagc tcataccatt cgaaacgatt atagttgccg ataaattccg
     3301 caacaaatcg gctctgagga ttctgataca attccttcga ggtggaaacc tgagccaccc
     3361 gcccagcttc catcacaaaa atccgatcac tgattcgcat cgcctcttct tggtcatgag
     3421 tcacaaaaat catcgtcatc cctagcgatt gctggatagc gcgcaaatcc cgctgcagct
     3481 gttttctaat tcgggcatcc aaagcactta atggctcatc cagcagcagg actttcggtt
     3541 cagtgaccaa tgagcgagcc agtgccaccc gttgtcgttg accgccagaa agaaactgga
     3601 catttttatc tgcctgctcc gtcatatcca ccaatgatag catctcaaaa accttttcct
     3661 gaatcacctc aggactcagc ttctttacct tcaaaccaaa ggctacattt tcaaaaacag
     3721 tcatagttgg aaacaatgca tactgttgaa aaacaaagcc gatattgcga tccttcgtag
     3781 gcttatcggc aatattctca ttgtccagca caatctcacc gctctttggt tgttccaatc
     3841 ccgtgataca gcgcagcaac gtagactttc cgcacccgct gggacctagt aaagtaacca
     3901 gctcaccctt ttcaatctga atttcatcaa tagctaaaat ctgtttttca tcaaaaaaca
     3961 gattgagatc atgtatttct aaaaacattt tccgtcacaa ctcctttaag ggcttctttt
     4021 tcgactgctt ctcttccctc gtctgcttaa gggacagctg ttgcttttgt cgataagtca
     4081 gcataaaggt agttaaagca attcccacca taaacagcaa atacaaaacc atcacagcgc
     4141 tagccaaatg gccgttttcg ttcatccgcc gcagcatata gatgcgtacc gtctgaaatc
     4201 gaccgccaat caacaggttc gtcagcatgt actccccaaa aaccgaagaa aaaatcatca
     4261 gagaaactag ggtcacaccg atacggatgt ttggaaacag cacctggata ataatcgtag
     4321 acatcggggc gcccaaggtt tctgctgcat ccactaattc cttcagatta attaagcgca
     4381 tctggttgtt aagactaaga tagacaatcg gcaacgccgt aataaacaat gcacctacca
     4441 acactacaaa cattgggata ccagtttcag catacgttcg aagcaaagcc gttaccaaaa
     4501 tcactcctgg taaagcatac ggcagcagga gcagcttttc cagccaacga ttcaaacgag
     4561 ggaaatacaa atgaatccaa ataatggtgg gaatcatcaa caacagaatc gtcaccaaga
     4621 ccacacctgc taataaaagt gagcgaccca ccgcagcaat aaattccctg tccgtcagca
     4681 gctgttggaa ccattgcaag gtaaaatcac taggtaaaag cgattttgac catttagtgg
     4741 agctggcata caaaatcgtt ccaataatcg gcagcaagta atacaggaca aagcagaaca
     4801 aaatcggttt tattaacttt ttcacgtctg caccaccttg cctttctttt gaataatcaa
     4861 cattgccgtt accagcagga cacctaaagc gactgccaac gcactgccta aattaggctt
     4921 ggcgaacaca tctcccgaca ctaaagccgc aattcgaatc gttaaaagat ttacattact
     4981 gctggtcagg gcatacgctg tttcataggt ccccatgcca ttagcaaata agatgacaaa
     5041 ggtgctggca atcgatggtc gcaaaaaagg caaagccacc ttgaaccaag catacgctga
     5101 tgaagcgccc agcaattgtg cggactccag ccattccttt ttcacttcct tcatgctggg
     5161 atacaaaaac aagaccccta acggaatttg gaaataggta tacgtgatgg tcaatcccca
     5221 ccaagaatac aaattgaagt ccgctagaaa tggcaaaatc attttcagca cacctacatt
     5281 ccccaacaaa ataataaaag agaatgccag cggaatccca gcaaaattag ctgccaaatt
     5341 ggaaacaaag gtgattttct cctgcaattt agtcgataga ttcattaagc ataaacataa
     5401 aataaacgtc ccgattaacc caatcacact ggagctgaca gcaatcagta cgctgttaac
     5461 aaaggcctgt gtgtaatatt tgttgctgaa aatatcactg taattggcca atgtccactg
     5521 gttagttaaa tcactgtgca agctgcacag aaccataaaa agcagcggca gcagtaaaaa
     5581 tgcacagaag ataaaggagg caggaaccag aaccaagcgt tttttcatct ctttcatccc
     5641 ctcatcaatt cttgaatgtc ctgcattttc tctgacggtg caattcctaa taaccagcaa
     5701 aacaatggag ccgccagcag ctgtggtaca gtttgttcct tcagcttttg gcgtttattt
     5761 gaaatcaaat aaaaaggaac ttcacgatgt gcagccaagc tgccgccatg cagtccgtgc
     5821 gcatccatcc cgtgatccgc agtcaccacg acttgataac ctttttgcag ccattcagga
     5881 aggtaaatag ccaataatct gtccgcctga ttaaccgctg ctgcatattc atgagaatcg
     5941 gcggtaaatt tgtgaccgac atcatcaata ttcatcgaat gtacgaccaa aaagtctggc
     6001 tgatactgat tcactaaata atgggcatcc gcaaataaat gcgaatcagg gtaagtgtcc
     6061 tcactataaa agatgccatg ctgaatcagt cgctcctcct gatgctggat gcgatcaacc
     6121 aaacgattat agggggcttg attgtacaac tcgctgtacc agtggtaagc ggcggctcct
     6181 gtttttccgc cagcttcctt aactaattca aacagcgacc actctttgga tcgctgagca
     6241 tggtaattac tatagatgcc attttcatag gctggaacgc cggtcatcag tacttcgtat
     6301 aacggacgtg aattgctggg cagctcactt tttaccttca ataagcttgc ttgctggtgc
     6361 tcaactaaat gattcatgaa cccaagctgg gcgacggctg tgtcgtagcg acagccgtct
     6421 agtataacta caatcagttt gtcaagtcta ctttgcatag gtcagtacct ccgcctgcca
     6481 aagctctgga agctctacag aggtcttgtt ccaagcttca ttgtcttcaa ctggcaccgc
     6541 cgcttcataa gcatcctccg gcagtaattt ttcagctact tctttaggca gctctacctt
     6601 gcgaataggt cgcgcatagc cctttgccaa attgatttgc ccttcatcag ataaaatata
     6661 ttcccgtgct agctttgccg cattgggatg aggggcattt ttattgatta aggttgtata
     6721 cccgctaatg atggagccgt ctgttggcac agttacctca aaacgctcgg agtcaatttg
     6781 gtcacgataa tttagtccat tgaagtccca aacaactgcc acatcgattt cacctttttc
     6841 aagatttgct acgctggcat caacggtgga caaacggcct ttttctgcca tttttttgta
     6901 gtaattcaga cctggctgaa tatccttttc gtcacctccg ttggcaatcg ccgcagccaa
     6961 tacagcaaat tgtgcttggt tggcaatcgt cacatccccc acgctaactt gatagtcacc
     7021 ctcttgcagc tccttccagc tagtcggtgc ttgcttcaca ttctctttat cggtgataaa
     7081 ggaaatggtt cccgtatagc ttaacaacca atccccatca tcatcctttg cccaatccgg
     7141 aatttcctcc caatagttgg tcttataagg taaggttaac tctttgcttt cagccaacgg
     7201 accgaagctg ataccgacat caccaatatc ggcggttcca ttttttcctt ctgattcaaa
     7261 cttagccaat tcttctgcac tggacatatc cgtatccacg tgacttaagc cgtattcttt
     7321 ttcaaggtcg ttccaagtgc ctacccaatt tgcccaagta tccggcattc ccaagctggc
     7381 aatctctcct tcttccttgg ctttttctat aatcgtatct aaagagtcgt ctgccgcagc
     7441 cgattgcttc gttgcttcac ctgagccgca gcctgtcagc aggatactta ctgttgctgc
     7501 acaaaataaa ccgatagtca tgttacgaat tttttcattc attttcattc attcttctcc
     7561 cctttcgata attccattct aacaaagctt tgtaatgaga gaatcagttt cttgaaaagg
     7621 tttcatgaac aatgtaaagg ttgtatatgg tttgtaaatt tcgacgaatt cccgttaacc
     7681 ttctaaagct tttgcggtat gatagtagaa aaaaggaggc tccctatgca gtattatgat
     7741 cagcatctcc acacgtattt ttcctttgat tcagaggaaa aatttgaaaa ctatttagcc
     7801 tatcagccgg agtttttcgt ttctacggat cactttgatt taaacaatcc atctaccgga
     7861 aaagatgaca ttccggatta tccagcctat ataaacaaac tggactcttt aaaagaaacc
     7921 tattccacca aatttctgcg aggtatcgag attggcgttg ttccaggaca agaagagcgg
     7981 atcgtggatt acctcgctca gcatccttat gatttaaagc tggtaagtat tcatcaaaat
     8041 ggccgctttg attatatgga cgatgtggtt ttaaccaaag atcccattca aactaccaag
     8101 gaatattttg atcagatgtt gcaggtcttg acggattttc cagaaggaga tattttgact
     8161 cactttgatt atggattacg ccgcttcacc ttcacagcgg aagaattcgc ggagcatttt
     8221 gaggctcagc tgctaacgat tttcaaaaag gttgttgaac gagaattggc gatggagtta
     8281 aatgccaaga gcttcttgaa atacggcaac gaagaccttt accgttatgc cgttcctttg
     8341 tatcaaagtg tcggcggaaa gctctttacc ttaggctcgg atgctcatgt tgccgaagat
     8401 tatcagctgg gctttaaaaa aatgagtcag ctgttggcag actgtcaggt agaaaagttg
     8461 ctagtcattc aaggaaaaga acgccgcctg acgccgctgc cgattttgtg attcctatat
     8521 aatagaagaa agtggtgaaa aaaatgagca acctgtggga ctacaatcaa gaggcaccca
     8581 tccattattt aattgcgcga cattgggatg cgttgaaaat tgaggcggtt tgccgatcct
     8641 tgttagcagc cgttccaaaa caacaactgg aaaatttttt ggtggctgac agcttgcagc
     8701 gggaaaaagt tcaggcttat tttgcagcct ttaaagatca gcctttggaa tatttgcatg
     8761 cgcagtttca tcttttttat caagtagccg ccccagatga ctacaacgat ttacgaggac
     8821 agctgcaatt gacctttcaa gcggatgaaa ccgcctatac cgttttattg ggaatggctc
     8881 gccttggtga tcaggcgaag gtcgagtggc ggattttcga tatttgatgg caggatcaag
     8941 gcgtttcagt tgcaaacctt cctctctttc aattagaaaa accgcagcag gaagaagttt
     9001 gtgtgctggt caccgatgct ggtgaaattc gtctccgctt atttcctgac caagctcccc
     9061 tggctgtagc caactggcgc tccctagctg agcaaggcgt ttatgacaac acacctttcg
     9121 gctcgtgtca ttaaggaatt tgttattcaa ggtggcgctt tggatggttc tggtgatgaa
     9181 gctgtttcca gctatgaggg ctttttcgct gatgaagtgc atcgcggact ttatcatttt
     9241 aatggcgcct tggccttagg ggaccacggc ccccacacca acggcaacca gttttttatt
     9301 gtgcaaaaca caaaggcgca ggctgacctg ctaatgtaaa gcaagcatac ttggagcttg
     9361 gaggactacc ggagctggat ggtcgttata ctgtttttgg acaggtatac caagggttag
     9421 aaatcgtagc agcgatcgca gctcagccga caaacagtga agatgtaccg attgagccag
     9481 tgttcattcg acaaattaac ttcgaaaaaa catcgtaaaa agacactcac tgacttcagc
     9541 aaaagctcta t
//
LOCUS       DADGKS010000089         9531 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.092, whole genome shotgun sequence.
ACCESSION   DADGKS010000089 DADGKS010000000
VERSION     DADGKS010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9531
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.092"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(129..776)
                     /locus_tag="JXV47_002480"
     CDS             complement(129..776)
                     /locus_tag="JXV47_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HAX1488490.1"
                     /translation="MEQTIKPYQYFFIKREVDQLLNAYSSVNDPKTVQTVQALAAEKI
                     RDILEHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(1055..1558)
                     /locus_tag="JXV47_002481"
     CDS             complement(1055..1558)
                     /locus_tag="JXV47_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAX1488491.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(1681..2445)
                     /locus_tag="JXV47_002482"
     CDS             complement(1681..2445)
                     /locus_tag="JXV47_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HAX1488492.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     NAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLADVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            2552..2827
                     /locus_tag="JXV47_002483"
     CDS             2552..2827
                     /locus_tag="JXV47_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HAX1488493.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            3504..4454
                     /gene="yidC"
                     /locus_tag="JXV47_002484"
     CDS             3504..4454
                     /gene="yidC"
                     /locus_tag="JXV47_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAX1488494.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPANNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(4633..5607)
                     /gene="lacD"
                     /locus_tag="JXV47_002485"
     CDS             complement(4633..5607)
                     /gene="lacD"
                     /locus_tag="JXV47_002485"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAX1488495.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPEYGLPAAALREKECGLLLAYEKTGYDTKIPGR
                     LPDLLNIWSVKRLKEAGADACKFLLYYDVDEPAEINVQKQIVIERIGSECEAEGIPFF
                     LEILSYDATIGDPSSLAYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QETCYSQAEASAYFYEQSKVTEQPFIFLSAGVNATLFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLEETATPVYVDR"
     gene            complement(5604..6062)
                     /locus_tag="JXV47_002486"
     CDS             complement(5604..6062)
                     /locus_tag="JXV47_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAX1488496.1"
                     /translation="MTIIHEENIFLQQPLDSQEEAFKFLAKQTFCLGIALDEKEVYQK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSMIIATLNKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRKAKSKTEIATILTKEIGEDL"
     gene            complement(6059..7522)
                     /locus_tag="JXV47_002487"
     CDS             complement(6059..7522)
                     /locus_tag="JXV47_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1488497.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGIKIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFAGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTVLADNEAADTLEPEAMSGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSFDPDHAQYNATAAMVKAVGDAAMGMMVPVLAAYIAEGIAKRPGLVVGFVGGIVAM
                     NGGTGFLGGILAGFLAGYFILFLQKLLTILPKQLDGLKAIFLYPVIGVAFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEHSNPLVLGVIVGCMCAFDMGGPVNKAAYVTGTALLAQGN
                     TTFMAGVSAACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKMDNKAANRTVIEKGRAGDLS"
     gene            complement(7504..8454)
                     /gene="pfkB"
                     /locus_tag="JXV47_002488"
     CDS             complement(7504..8454)
                     /gene="pfkB"
                     /locus_tag="JXV47_002488"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010779385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAX1488498.1"
                     /translation="MSIYTCTMNLAIDLFIETEEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQQKQIQTEFIEVPGMTRINVFTQVNQTGEE
                     YKLVNQGPKIPQTAVHNFLNQIRALQAEDYLCVSGSLPRGLSPKVLIEISRICQEKGI
                     HLIIDSSDQEAMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVELGAENV
                     LLSLGEKGAILFTKDRVFRGNSPKGKVVNTACAGDTMLGAFLAGYMNRRPLDETLRKS
                     IAAGSSTAFRKGLTDFLDVEELSKQIKIKEERFETWENIN"
     gene            8597..9346
                     /locus_tag="JXV47_002489"
     CDS             8597..9346
                     /locus_tag="JXV47_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAX1488499.1"
                     /translation="MDHKLSETEQYLWNFIEHHILEIPNYSIVKLSEQANVSTATIVR
                     TMKKKGYEGFTSFKHHLKEGENKNINFSFLDKVDKGIRRAILKNEQEVVRTINMLEIG
                     NIEDAIQRIKFADRVFVFARGFSEMIGQEMLVKLQLTGKNCQMHTDPEIIKSISRKLT
                     KKDSVIFVSLNGETKELVTAAKNCYDAEIGSILVTANHSSTLKDYCEINLVGFKSEGS
                     YFPDYEVRSRLPLQIIARILLDAYVLRMGEN"
BASE COUNT         2854 a         2007 c         1643 g         3027 t
ORIGIN      
        1 aagaaagggg ctatccccag actttagtag gcgtcattag ctatctttcg ttagcattta
       61 aaggcgaaca ccatcaccta ttcacttcca ttaaaagata gcatattttt ctgtaaaaaa
      121 caataaaatt atcgttcttt ctttacacgt tcagcaaatt catagaaagg agccaatttc
      181 gttaactgtt gattacattg gtcactatca tgacaaatat aattcccctt tttcgtatac
      241 gtgccatcag aacctgcttt cgttgtagaa agaaaaagcg acacattcga tgttttctga
      301 cagattgcac agattccctt atttatcgtt ggtgataaag taccgctaat cccttttaat
      361 ttttcatctt cgtaatagac catgaatttt ttctgcgtac ctggatcatt ccagccgatg
      421 tacgtatgtt cttgcaagtc gatttcattc caagctggtt gtttgagttt tttcactttt
      481 cggaataatt tctcgatttg tggtttgcta ggctgcataa acggctggac gatttgcttc
      541 agctcctcca atgctctttc tgcttgcgct tttgtcagtt ttacgtctaa aactgtcgtt
      601 aaaaatgtat cgatttctgg cagttcgtgt tctaatatgt ctcgaatctt ttcagctgct
      661 agtgcctgaa ctgtttgtac cgtttttgga tcattgacag atgagtacgc atttaataac
      721 tgatctactt ctctttttat aaaaaaatat tggtatggtt ttattgtttg ttccatgatt
      781 ttaaagtcct ttcttctaac caaagtgcat actttgtaga aaaaagtgat cttctgcaaa
      841 gtatgtgtta cctgaagatc ccggactctt ttaaataaga tacgttttgc atcttatcat
      901 cacccccttt aatgttcatt cttctatgta catgattcat tcgataaata aaagtaaacc
      961 gtatcttgaa cagatagtca actgcaaaca gaaaaaaccg agaaaatcag ccagattttc
     1021 tcggaatata gtctattatt attggtttta cctattaaat cgaggattct ttcccaaagt
     1081 aacgttgcca tctcttacgc atacttgcag acatgggctg agccgcttct ttgactgcgc
     1141 agtatttgtc cacgaatgtc acaatatatc cttctttata cttaggcggt gcgatcgttg
     1201 caccccacat gtgcttcaaa atgatatctc gctcaagatc cgacaaatcg gtgatttttt
     1261 ctgcattctt tacagcaatt cttggatgga tatacgcatg tgtcccctcg tcaaatttcg
     1321 tcgtacgcca atcatagtag aacagatcat gcaaaagtcc agcacgcgct gttgctttag
     1381 cattgccacc ccattttttt gcgagcagat aactatagta agaaacactg atggaatgct
     1441 ccaaacgagt ggaatgaaca tgctgtgtgt aattcgctaa ttttttcact gcttctgttt
     1501 ctaaaagatc ttgtacataa gacatatatt cttcgtcttc acgccatttt tctgtcataa
     1561 ttatcgatct gccacctttt tgaatttcat tttcttctga aattgatcta agtataccac
     1621 cagtgttcgg attattctag tcgctctaga taaaatagct aaagcttaat agttccttaa
     1681 tcataaagaa aaatgataaa gaacgatccc tgctgcgact ccgacattca atgattccgc
     1741 atttcctttc attgggatat atacgttctg atcagtcaaa gacaagattt cctgacttac
     1801 tccctgacct tcgtttccca tgattatagc gaaatcctct gttttttcta ctttgtctaa
     1861 tgcatgtgct tcttcattta attctgtacc gtacaccgta aaccctttgc ctttcattac
     1921 agggattaca tctgccaaat ctttttgtaa cacaggcaaa tgataattgc ttccctgcat
     1981 gcttcgcagc acctttgtac tataaatatc tgccgttcct ttacctaata aaacaccagc
     2041 cataccaaac gcatctgccg tacggatcat cgttcccaca tttccaggat cctgtacatt
     2101 atctagtaaa agccagcctc ctgaaaaatc tggcgtatct tcagatgtta acgtcatcac
     2161 tgctaagatc ccttgcggtg taggtagatc tgacatagcg gtcatgacct catctgaaac
     2221 tagaaaagta gaaatctctt tgtttacagc cagccagtct ccccattctt tcatacctct
     2281 ctgtgtcaca aaaagttctt ttatttctgc attagacgac gcagcttctt cgatcagatg
     2341 gaacccttcc aaaagatatt ctgccttttc ttctctgtat ttctttttat gtagtttttt
     2401 taattctttg attcttggat tttttgctga ttggatctct ttcacattcc tcacctcaac
     2461 tgattatatc atggaatagg tgcttgagct tgtttcatcc taaaaaaatc ggtatcattg
     2521 atttataaaa caggaaagaa aggtgacgaa catgcgcaaa gttaaaatga atgtccaagg
     2581 acgtgtccag ggcgtgggat ttcgctatat gaccaagatg gttgctgatc agttaggcgt
     2641 gaccggaacg gtaaaaaacg aagacgacgg ctcagtcaca atcgaagcaa tcggaaatga
     2701 cgacatcatc caaaaattta tcgaagaagt caagaagtct ccgagcccaa gtggacgagt
     2761 gcagtatgtg gatgtccaag aagatccgat gattgaggaa cgaaagaaat ttgatgtagt
     2821 gggataaggt tgtgaaaagg tcgcttagtt ttgagtatta aggaaaattt tgtgaaaatg
     2881 gctttccaca tttttgcata aatttgactt aataccgaga aactgacttt tgaacaccgt
     2941 cgataaggtt gtttttgaag cgctttgcct cgagtattaa ggagaaacat tttcaaaata
     3001 gcttctcata ttttgaaatg taatgactta ataccgagag gcagctgata aaacaccgtc
     3061 aataaggttg tgaaaaagct ggtctgcatc aagcattaag gactggttgt gataaatagc
     3121 tctccatatt tttcaacagg ctggacttaa tgccgtagat gcaagctttt gaacaccgtc
     3181 gataaggttg tttttgaggc gctttgcctc aagtattaaa gacaggtagt aaaaaagctg
     3241 atctataact tgcaatgaat ttgcttaacc catattttcc agacagaaca aaaaagtttt
     3301 tagtttttta aataagaaag aaacacttgg aatcactctt ttctttctaa gtatttcttt
     3361 cttgattttt tgtctttttt caaaattttt cgctacgaaa aagaacgaat atttatatga
     3421 aatttctatg aagttgattg aattccatgc gcttttttag tatagttaag tttgtgtaaa
     3481 aattatagaa gaggaagtat tctatgaata aatggaaaaa ctggttattg ggatccggac
     3541 ttgtcagtat cctgctcttt ttatctggct gtgtgcggat ggattcaaac ggaaaccctg
     3601 acacttcagg aatcgtttat cgagtactcg tccatcctat gggccaagcg attacatatc
     3661 tagttgagaa tttcaattgg tcttacggct gggcagttat tgcaatgact gtgatcgttc
     3721 gtatcatcat cttgccacta ggtatcagtc aatcgaaaaa aacaatgatc caatctgaaa
     3781 aaatgcaagc gttaaaacca caagttgaag cagcacagca aaagctaaaa gctgcaacaa
     3841 cacgtgaaga acaaatggca gcacaagcag aaatgcagca agtatatcgc gaaaatggat
     3901 tgagtatgac cggcggaatc ggctgtctgc ctctattgat ccaaatgccg atcttctctg
     3961 ccttgtattt tacggcacgc tacacagaag gtatccggga atcatctttt tacggcatcg
     4021 atctaggctc accaagtatg gtgcttgtgg ccatcgcagg ggtcgcttat ctgcttcaag
     4081 gatatatttc aacaatcggt attcctgaag aacagaaaaa gacgatgcgt acgatgctga
     4141 tcgtctctcc tgctatgatc gtcttcatgt caatcagtgc gccagccggt gttacacttt
     4201 actgggtagt cggtggtgtg ttcagctgtc tgcaaacatt catcacaaac gttatgatga
     4261 aaccacgttt gaaagcacaa gtggcagaag agttgaaaca aaacccgcca aaacaagtcg
     4321 tcactccaag aaaagacgtg acagaatcag caaagccagc taacaacaaa caagcaacaa
     4381 aacaaatcaa acaaccaaaa aacagtacaa acaacaaagg ccgcaacgca ggaaagcagc
     4441 agaagcggaa gtagatagta aataagagtg taataaaaat tcattaacag ttttagcaat
     4501 taaaaatatc gaccaagatt tttgaaaaag aaatctggtc gatattttta tttaagtgaa
     4561 tgtttaattt gaatcatcga ttgatcgcta tctaattgca gcagcatctt tttatgaaga
     4621 aacaactttt tcttatctat caacgtagac aggtgttgct gtttcttcta atagtgtact
     4681 taattcttta atattttgtt ttccttcttc taacatccaa ctactcgctt tttcttcgcc
     4741 ttcggtaaca aaaggtgcca ctcccttcgc ccatgttgct cgcccacata agacaccatt
     4801 gaatgtcgaa cctgattgtt ttgcaaaacg taatgtatct tgaaatagcg tagcattgac
     4861 tcccgcactt aaaaaaataa acggttgttc agtcactttc gattgttcat agaaatacgc
     4921 ggatgcctct gcttgactat aacaagtctc ttgcccatat ccttccacaa atctcatatt
     4981 cactggcact tctactttca atacatccac ttgataacgt tcttttgaaa attctcgcat
     5041 ggcttcaata actttatgtg gttttacttt tgcataggca agagaagacg gatcgccaat
     5101 agttgcatca taagaaagaa tctctaaaaa gaaaggtatg ccttctgctt cgcattctga
     5161 accaatccgt tctataacta tttgtttttg cacattaatc tctgctggtt catcaacgtc
     5221 atagtacaat aaaaatttac aagcatccgc accagcttct tttaaccttt tcaccgacca
     5281 aatattcaat aaatcaggta atcttcccgg tattttcgta tcatagccgg ttttttcata
     5341 agctagcagt aagccacatt ctttctctcg aagcgctgct gcaggcaggc cgtattctgg
     5401 atcaagtaaa atagctgagg catagggagt caggtattga gaaaccatct gtttaaattg
     5461 gatgatgtct tctgatgtag cttctttata ttggttgatc attttcttca aagcaccacg
     5521 ctggtcgatt gctaatgcgc taataattcc agcttcatcc gtcaatcgct tcaaacgttc
     5581 ctgtttttct atactcatct tcttcataga tcttcaccta tttctttagt taatattgtg
     5641 gctatttctg tttttgattt tgcttttctc aactgttctg taacctcttt tcgcatcaat
     5701 gatcgtgcaa cgagagacaa taatttcaaa tgagtcgttc ctgcttctga atctggaata
     5761 aataacgcaa aaataaaatc aactgactgt ctatctaaac tgttccattc aattcctttg
     5821 ttcagtgtgg cgataatcat actaggttcg ttgattgttt gagacttcgc atgagggata
     5881 gcaaaacctg acattattcc tgtagtccct tctttttctc tttctagaag tttttgatat
     5941 acttcttttt cgtcaagagc gatccctaaa cagaatgttt gctttgctaa aaacttaaat
     6001 gcttcttctt gactatccaa tggctgttgt aaaaaaatgt tctcttcatg aatgattgtc
     6061 atgataagtc tcctgctctt cctttttcga taactgtacg atttgctgct ttattatcca
     6121 tcttcttgtc tttatcagtt actcttttct tttggattaa tcctagtatc actccaccaa
     6181 cgatcgaacc aataagaatc gctgtaaccc attggatttt tcccgtcact acaggtaaca
     6241 ctaaaaaacc accatgtggt gctggaactt ggacgccaaa caaataagtt aagacagcag
     6301 caattgatga gcctaacatc atcgtgggta acactcggat cgggtctttc gcagcaaacg
     6361 gaatagctcc ttccgtaata tgagttgatc ctaaaataaa attaaccaaa cctgcattac
     6421 gatcattggt atcaaaatat ttaccaaaca ataaagtagc aaaaccagta atcaacggtg
     6481 gtgcaataca agctgctgac acaccagcca taaaagtcgt gtttccttgt gccaaaagag
     6541 ctgttcctgt tacatatgcc gccttattaa ccggtcctcc catatcaaac gcacacatac
     6601 agccaacaat cacgccaaga acaagtggat tcgaatgttc aaatccagct aaaaagctca
     6661 tcattccttc atttatagcc ttcattggac ctgccagcaa agacatcacg atgccaataa
     6721 atgctacacc aataactgga tataagaaga ttgccttcaa gccatctagt tgtttaggta
     6781 aaattgtcag tagcttttgc aaaaataaga taaaataacc tgctaagaac ccagctaaaa
     6841 tacctcctaa aaatccagta ccgccattca tggctacgat tccaccaaca aatccaacga
     6901 ctaaccctgg acgtttcgcg atcccttctg caatataagc tgctaaaact ggaaccatca
     6961 ttcccattgc tgcatcgcca actgctttta ccattgccgc tgtagcattg tattgtgcat
     7021 gatctggatc aaaagaatag attccccaaa cggcaaatga aatagcaatc aatactccgc
     7081 cagctaccac gaaaggcaac atatgagaga caccgttcat taaattttta tagatgctac
     7141 gaccaaaatt agcaccactc atcgcttctg gttctaaagt atcagcagct tcattatctg
     7201 ctaagacagt accttttcct gccaatgctt cgtcaatcag ccgttgtgca tccttgattc
     7261 ctgtactgac agaaacatca atgactcgtt ttcccgcaaa tctttctgaa tggacatctt
     7321 tatctgcggc aataatgaca gcatctgcct gtttgatttc ttcagccgtt aattcatttt
     7381 cgatcccaat ttgtccatgg gtctccactt tgatcttgat gccttttttc ctagctgctt
     7441 gttctaatgc ctcttgcgcc atgtaagtat gcgcaattcc tgtcggacaa ccggttgctg
     7501 caattagttg atattttccc atgtttcaaa cctctcttcc ttgattttga tttgtttact
     7561 taattcctcc acatccaaaa aatcagtcag tcctttacga aaagcggttg agctgcctgc
     7621 tgctatgctt ttacgtaacg tttcatcaag cggtcgtcga ttcatatatc ctgctaaaaa
     7681 agcgcctaac atggtatcac ctgcacatgc tgtattgaca acttttcctt ttggcgagtt
     7741 tcctcgaaac accctgtctt tcgtaaaaag aatcgctcct ttctcaccga gggataacaa
     7801 aacattttct gcacctaact ctactagtcg ttgtccataa acaaagtaat cttcatctgt
     7861 aaccattttt cgtccgaacc aagaagaaag ttcttcctcg ttcggtttca gcaaaaacgg
     7921 tcgatagggt aaacaatcca tggcttcttg atcactacta tcaataatca aatgaatccc
     7981 cttttcctga caaatccgac tgatttctat taaaaccttt ggagacagcc ctcttggtaa
     8041 actcccagaa acacaaagat aatcttctgc ttgtaatgct cttatttgat ttaaaaaatt
     8101 atggacagct gtctgcggta ttttaggtcc ttgattcact aatttgtatt cttctcccgt
     8161 ttgattgact tgtgtaaata cattgatacg cgtcatacca ggcacttcaa taaactctgt
     8221 ttggatttgt ttctgctgta aatagtcttc tatatacttt cctgtaaacc cagcagaaaa
     8281 acctaatgcc gtacttggga aatctagcat ttttaatact agtgacacat tcaccccttt
     8341 tccgtttgcc tgaatgtcat cctcttttgt gcggtttacc ataaaaggat gcatctcctc
     8401 tgtttcaata aatagatcaa ttgccaaatt catcgtgcat gtgtagatag acataaccaa
     8461 cgacctcctt gactctatta tgaaatacgc gaaagagaaa atgttttctt aatcgtccca
     8521 acacaaagaa aacctttaca tttataaact cgtcgtgcta ttttttaact aacttttggt
     8581 gaaagaagga aagaatatgg atcacaaatt aagtgaaaca gaacagtacc tctggaactt
     8641 tatcgaacac cacatcctag agatccctaa ctactccatc gtgaaactaa gtgaacaagc
     8701 aaatgtctca acagccacca ttgtgcggac aatgaaaaag aaaggctatg aaggatttac
     8761 ttcgtttaag caccatctaa aagaaggaga aaacaagaac atcaattttt ctttcttaga
     8821 taaagtagac aaaggtatcc gtcgagccat tctaaaaaat gaacaagaag tggtacgtac
     8881 gatcaatatg ttggaaatcg gaaatattga ggatgcaata caaagaatca aatttgctga
     8941 ccgggttttt gtctttgcac gaggattttc agaaatgatt ggtcaagaga tgctcgtaaa
     9001 acttcaatta acagggaaaa attgtcaaat gcatactgat ccagaaatca tcaaaagcat
     9061 cagtcggaaa ctaactaaga aagacagcgt tatttttgtt tctttgaacg gcgagacaaa
     9121 agaactcgtc accgccgcaa agaattgcta tgatgcagag attggttcga ttctagttac
     9181 agccaatcat tcctctacac tgaaagacta ttgcgagatc aatctcgtag gtttcaaatc
     9241 agaaggttct tatttccctg attatgaagt acggtcacgt ttgcctctcc agattatagc
     9301 gagaatcctg cttgacgcct atgtattgcg tatgggggag aattgaaaag cagtttatta
     9361 tggttggtta cagtttaaaa catcacattt tttattcttt atattgtatg gactcacgga
     9421 aactttttat gtataaagtt attcacaatc tataaagtta ctttaaataa caaaaaaata
     9481 attgaaaata cttaaaatca aaaaatatct ttttaatcaa taaaaaaatt g
//
LOCUS       DADGKS010000090         9432 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.093, whole genome shotgun sequence.
ACCESSION   DADGKS010000090 DADGKS010000000
VERSION     DADGKS010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.093"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..680
                     /locus_tag="JXV47_002490"
     CDS             <1..680
                     /locus_tag="JXV47_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAX1488500.1"
                     /translation="YFSRFSLATREAVQWIVIDMYAPYVSLVKKLFPNAQLIIDRFHI
                     VQHIGRTFLNHRVKETTARLKGTSHSQRGLGKKLKRYWKLLQKEEAKLNYEKRVWRAS
                     FKDYLTESEIVDRLLSACPNLRQGYQLYQDILYAVKKRDQSLFEDCLNREVSGLPETY
                     TTTLRTFKKFLPQIQNALHYSYSNGPLECLNNHIKVLKRNAYGFRSFYNFKLRIMIRH
                     GKTFLTK"
     gene            800..1000
                     /locus_tag="JXV47_002491"
     CDS             800..1000
                     /locus_tag="JXV47_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAX1488501.1"
                     /translation="MIEEEQKNIWDRYYKADPSSKNTKIGESGLGLSIVKELVRLHHG
                     SIEVTSRKNEGTTFLIQFPKEK"
     gene            1076..1273
                     /locus_tag="JXV47_002492"
     CDS             1076..1273
                     /locus_tag="JXV47_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488502.1"
                     /translation="MVECLKNKKMEANFVKAVISGSIVFQEEYRDMEKDFSKKGIELI
                     DYPRSCPILDKEYPEILTTFF"
     gene            complement(1570..3117)
                     /locus_tag="JXV47_002493"
     CDS             complement(1570..3117)
                     /locus_tag="JXV47_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HAX1488503.1"
                     /translation="MNITFLETSDMHGYVSPTDYSGRTDLALGTAKVSSKLKELRAKA
                     DGPVITIENGDFIQGSPLSYYLAKEYGSAKELTDLINQMSYDVQVLGNHEFNYGVDYL
                     EEAIKNYQAPILGANMVNKNDQPYFGNAYKIIEKVGVKIAILGLTTQYIPHWEKPETL
                     AGITFKSIVETAKEYVPLLRKQADLVIVSYHGGFEKDLLTGEDTEALTGENEGYELLQ
                     QVEGIDALFTGHQHRKIAETVHGVPVVQPGYRGEFIGEIRLTVEKKEGQVVVTDHQVA
                     LHSVEKSEPDPEILAAIVPVEEKLEKWLDQPLGKVNGNMRINDPMQARLEEHPYVEFI
                     NRVQLFASGSEISGTALFNNEGKGFGETITMRDVITNYIYPNTLAVIQINGADLRAAL
                     EQTANYLAVENNQIVFNPAFIQPKPQYYNYDMYEGIQYTIDMKQPVGQRITELRFKGH
                     PVLPQQMLEVVTNQYRAIGGGNYAMFGAEKIVREIQIDMTELIADYLNIHPRIEAKVN
                     HNFQVIL"
     gene            complement(3201..4004)
                     /locus_tag="JXV47_002494"
     CDS             complement(3201..4004)
                     /locus_tag="JXV47_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAX1488504.1"
                     /translation="MNILHISDIHFRREYEACEEGYKGMLATMQNPLIPLEQCIHHLL
                     QQTPLDLVIISGDLTEDGEIDDYRYLKTWLENALGETTILVTLGNHDIKEHFWVGWCD
                     EAASSAPYNQIVKYPEFTVISFDNSSYGYADGIVDDQQFQWLKKALEQEKDQPIFLVT
                     HHHLLSHQSSIPKWPGTERFLKLIAPYDIRCILNGHTHHTFTDEINGIPYFTVSSMSF
                     VGEDEGDGFVRFEERHGYNLYHLDQGRIVRQTTENFIPGNILKTLQMKD"
     gene            complement(4007..4789)
                     /gene="phnE"
                     /locus_tag="JXV47_002495"
     CDS             complement(4007..4789)
                     /gene="phnE"
                     /locus_tag="JXV47_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HAX1488505.1"
                     /translation="MMLREMNRRTLLSLVALVILVILSAATLDYSGLSTFSPSMGMDV
                     LRGLGQPDWQFLYDGSGEDLISLLLLTIGIACLGTMIATVLAIPITLISAVNLWQAHP
                     WVTKIGKLICNVLRAFPELVFAIIFVKVVGPGPFAGVMAIGVHQIGMLGKLFTEEMEA
                     MDERLVEEMHAVGANFWQTIFFVRIPYLMPIYCSLALNHFEIAVRSAATLGLVGAGGI
                     GAPLIFAIQTRSWSKVSIILIGVVVTVFILDQITGIIRKRLR"
     gene            complement(4786..5565)
                     /gene="phnE"
                     /locus_tag="JXV47_002496"
     CDS             complement(4786..5565)
                     /gene="phnE"
                     /locus_tag="JXV47_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HAX1488506.1"
                     /translation="MSLKETVHFKWYKHLLILLFLIVCFQGSAWITSADFSQVFQNSN
                     QMTVFLSRFIHPDFSYLPKLVEPMVKTLQMSLLGTVIGLILAIPVSFLATTVVTENRL
                     LSTIFRFLLGLVRTIPTLLLAALFVAVFGIGEATGVLTIAVFTFGMVSQLMFQAIETI
                     DFGPIEAAAAVGANKMQIAIWSIAPQVLSQFASYAFYAFEVNVRASTVLGYVGAGGIG
                     VILNSSLALLNYERVSIIILTILVTVAIVDKLSERVRRSLL"
     gene            complement(5537..6328)
                     /gene="phnC"
                     /locus_tag="JXV47_002497"
     CDS             complement(5537..6328)
                     /gene="phnC"
                     /locus_tag="JXV47_002497"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter ATP-binding protein"
                     /protein_id="HAX1488507.1"
                     /translation="MIIFDNVSKVYPNGVVGLKDIDLTIEDGEFVSIIGLSGAGKSTL
                     LRSINRLAETTKGDIRINGTSITKANKKELRQIRRQIGLISQSFNLVKRSTVQKNVLS
                     GRLGYYSTWKSILGLFTKEDYQQTKEALEKVGLSDKLQTRSDELSGGQQQRVSIARAL
                     VQQAPIILADEPVASLDPITTQKVMMDLKNINQTMDKTVIVNLHSVPLAREFSTRVLA
                     LKAAQVVFDGRPDDLTDERLEQIYGNAIFEEKAGEIDELERNRSL"
     gene            complement(6389..7318)
                     /locus_tag="JXV47_002498"
     CDS             complement(6389..7318)
                     /locus_tag="JXV47_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate/phosphite/phosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HAX1488508.1"
                     /translation="MQFKQLAKGFIGVMLLTTLAACGSGNTSSSSEKESKEKLVVQFV
                     PTNNDGSMEAKAKPFAKYLSKKLDREVEVTLATDYSTIVEAMSSGQVDVGIMPPAAYV
                     QAKDAGAADAILTSQLGDYDQETGLPLKDKLTNTFKGEVLVRADSGLNKLTDLKGKNI
                     ATLSPNSASGYIYPVAELKDAGIDPTADTKMTTVNDIPSEITAVLNKQMDAAFVFEGA
                     RNVFASNFPDNDLFKDLKVLYLTKGDIPNDAIAVQPDMSKDLKAKIKETFLNMKDDKD
                     GKEAMALWGHQGYEEAADSAYDTIRDYTKKAAE"
     gene            7513..8196
                     /locus_tag="JXV47_002499"
     CDS             7513..8196
                     /locus_tag="JXV47_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HAX1488509.1"
                     /translation="MKKIHDTKQLTAYVEKHNLQDYMDSDILAMASLLFFEKEEHLIQ
                     TGKTSDYLYFLVDGTVMVYSYSSDTQNICIDYAKPATPLGEASSLWELSPKSSVKAVT
                     KCICISIPLNQYRTQLQKDVRFLQNICQLLSYRLNSGINLANSLTEPVETRLAKFILT
                     HHENERFSFRLTTCASILNVSYRHLLRTITNFREENIIEKKKNYYLIHDIEALEDLAE
                     NISSPVKAE"
     gene            8357..9400
                     /locus_tag="JXV47_002500"
     CDS             8357..9400
                     /locus_tag="JXV47_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HAX1488510.1"
                     /translation="MKKILVSLLFLVSLVTLVGCSQSQGEKQSEKEKSKIALVLGFGG
                     VDDRSFNQAGWEGLEAWGKEKKLTAKKDFTYIETNNPEDNSTNIDQAIRNGFTTIISL
                     SYLQAEELENAAKDNPKLKFALVDGEITGKKNISSATFKDQESAYLAGLAAAYTTKSD
                     QVGFIGGMEGPVIQRFQSGFEAGVKAGATALNKEITVNVQYAASYDSLDKGKAIAASM
                     YKEGVDILYQAAGSTGAGVFQEAKARNENDYSRKVWVIGVDRDQADEGDYKMENGETG
                     NFTLTSTKKNVGAEVKEFAETSHNDKFPGGKHLTFGLKEEGVDLTKGQLSEEAYQAVS
                     DAKEKIISGDFRL"
BASE COUNT         2893 a         1933 c         1869 g         2737 t
ORIGIN      
        1 gctatttttc tcggttttca ttagcgactc gtgaagccgt tcaatggatt gttattgata
       61 tgtatgcgcc ttatgtttca ttggtgaaaa agcttttccc gaatgctcag ttgatcatcg
      121 accgtttcca catcgtccaa catattggca gaaccttctt gaatcatcga gtgaaagaaa
      181 ccacggcacg gcttaaagga acttcccact ctcaacgagg gttagggaaa aaattgaaac
      241 gctattggaa actcctacaa aaagaagaag caaagttaaa ctacgaaaaa agggtttggc
      301 gtgccagttt taaagattat ttgactgaaa gtgagattgt cgatcgactg ttatctgctt
      361 gtcccaacct gcgccaaggc tatcagttat accaagacat tctttatgcg gtaaagaaaa
      421 gagatcagtc attatttgag gactgtttaa acagagaagt cagcggtctt cctgaaacct
      481 atacaaccac tttacgaacg tttaaaaagt ttctgccaca gatccaaaat gcgcttcact
      541 acagctattc aaatggacca ttggaatgtt taaacaacca catcaaagta ttaaaacgca
      601 atgcgtacgg ctttcgcagc ttttacaatt tcaaactacg gatcatgatt cgtcatggca
      661 aaacattttt aaccaaataa acagaacaga aagagagttt cttctttctg ttctgtccaa
      721 attattctaa gatttctctt taccaacatc atttgacaaa gagcctgtat ttattactgt
      781 cgaggacaat ggcatcggca tgattgaaga ggaacaaaaa aacatttggg atcgctatta
      841 taaagccgat ccgtcaagta aaaatacaaa gataggcgag tcaggtcttg gattatcaat
      901 cgtgaaggaa ctagtgcgcc tgcaccacgg ttcaattgaa gtgaccagcc gaaaaaatga
      961 aggaacgacc ttcctgatac aatttccaaa agaaaaataa aattaccagt aaaaaaccgt
     1021 ggagagatag ctgctattga tttttgctat gtcttttctt tgagaggtat ccggtatggt
     1081 ggagtgtctg aaaaataaaa aaatggaggc caattttgtg aaagctgtta tttctggaag
     1141 tattgttttc caagaagaat atcgagatat ggaaaaagat ttcagtaaaa aaggcattga
     1201 attaattgat tatcctcgct catgtccgat cctagacaaa gagtatccag aaatcttgac
     1261 gacttttttt taaatatcgc agcagcggat ttattttttg tatttaatca agatcggaaa
     1321 ggggtattag gctatattgg tgccgcaact ttttcagaaa tgaagtattg tctgatgcaa
     1381 aatcttattc atggaaaaag gatcaaaata gtcttattta aggaaccatc agaggaaaat
     1441 tttttgtttt gatgaggtag atcgctggct aaagaatggc tggatggaaa tcagacagcc
     1501 taacaatttg gcataacaaa ggtgtgggca aaaaactgct cacacctttt tgaatttttt
     1561 atttatatac tacaaaatca cttgaaaatt atgattcact tttgcttcga tgcgtgggtg
     1621 aatattcaaa tagtcggcaa ttaattcggt catgtcgatt tggatttctc ggacaatttt
     1681 ctccgcacca aacatcgcat aatttcctcc gccgattgcc cgatattgat ttgtcaccac
     1741 ttccagcatt tgttgcggaa gaacggggtg acctttaaaa cgaagttcgg taatccgttg
     1801 tccaacaggc tgtttcatat caatagtgta ctgaatccct tcatacatgt cataattgta
     1861 gtactggggc ttaggctgaa taaaggctgg attgaatacg atttggttat tttctacagc
     1921 taaataattt gcggtctgct ccaacgccgc tctcaaatct gcaccattta tttgaatcac
     1981 tgccagagta ttcggataaa tatagttggt gatgacgtcc cgcatcgtga tcgtctcacc
     2041 aaagcctttt ccttcattat tgaataacgc agttccagaa atctctgagc cgctggcaaa
     2101 taattgtaca cgattaataa actctacata gggatgttcc tcaagacgag cctgcatcgg
     2161 atcattaata cgcatatttc cgttcacttt acctaagggt tgatccaacc atttctctag
     2221 tttttcttct accggtacga tcgctgcaag aatttctgga tcaggctctg atttttcaac
     2281 tgagtgtaaa gcaacctggt gatctgtaac aaccacttgc ccctcttttt tctcgacggt
     2341 aagacgaatt tcaccgatga actcgccacg atagcctggt tgaacaacgg gaactccatg
     2401 aaccgtttca gcaattttcc ggtgctgatg accggtgaaa agggcgtcaa tgccttcaac
     2461 ctgctgcaat agctcgtagc cttcattctc tccagttagc gcttctgtgt cctcaccggt
     2521 taacaagtct ttttcaaatc cgccgtggta actaacgatt accaagtctg cttgtttcct
     2581 taatagagga acatattctt ttgctgtttc gacgatactc ttaaacgtaa ttcctgctaa
     2641 ggtttctggc ttttcccagt gaggaatgta ttgtgtcgtt aatcccaaga tagcaatttt
     2701 tacacccacc ttttcgataa tcttataggc gtttccaaag tatggttggt catttttgtt
     2761 caccatattg gctcctaata taggcgcttg ataattctta atcgcttcct cgagataatc
     2821 cacaccatag ttaaactcat gatttcccaa cacttgaaca tcatagctca tttggttaat
     2881 caagtctgta agctctttgg ctgaaccata ttctttagca agataataac tcaaaggaga
     2941 cccttggatg aaatcaccat tttcgatcgt aattaccggt ccatctgctt ttgcccgtaa
     3001 ttccttcagt ttcgacgata ctttagccgt tcctaaggcc agatcggttc tgccggaata
     3061 gtctgttggt gaaacatagc catgcatatc acttgtctct aaaaacgtaa tgttcattct
     3121 gcgtgctcct ttagctgact caaaatagaa aaaccgaagc gtattcagct gttcggtctc
     3181 tttttttgat ttataatgcc ttaatccttc atttgaagtg tttttaaaat gttgcctgga
     3241 ataaagtttt ctgttgtctg gcgaacaatc cttccttgat cgagatgata aaggttatac
     3301 ccatgacgtt cttcaaagcg tacgaagcca tcgccttcat cttcaccaac aaaggacata
     3361 ctcgatacag taaaataggg gatcccatta atttcatcag taaatgtgtg atgggtatga
     3421 ccgtttagga tacagcgaat atcgtaaggt gcgattagct tcaagaaacg ttcggtacca
     3481 ggccattttg gtatactgct ttggtgagac agtagatgat gatgggtgac caagaaaatc
     3541 ggttggtctt tttcttgctc taaggctttt ttcagccatt gaaattgctg atcgtccact
     3601 ataccatctg cgtatccata gcttgaatta tcaaaggaaa tcactgtaaa ctcaggatat
     3661 ttgactatct ggttgtacgg ggcagaagag gcggcttcat cgcaccagcc tacccaaaaa
     3721 tgttctttga tatcgtgatt gcctagagta acaagaatcg tcgtttctcc tagcgcattt
     3781 tccagccaag tcttcaagta tcgataatcg tctatttcgc catcttcggt taaatctccg
     3841 ctgataatca caaggtccaa gggtgtttgc tgcaggagat gatgaatgca ttgctccaga
     3901 gggataaggg gattctgcat cgtagccagc attcccttat agccttcttc acaagcctca
     3961 tactctctgc gaaagtgtat atctgatata tgcaatatat tcattcttat ctcaatctct
     4021 ttcttataat tccggttatt tgatctaaaa taaacacggt tacgactacg ccaatcaaaa
     4081 taatactcac tttgctccaa gaccgagttt gaatcgcgaa tatcaatgga gcaccgattc
     4141 cgccagcgcc aactaagcct aaggtagccg cactacgaac cgctatttca aaatgattta
     4201 atgctaaaga acaataaatc ggcatcaaat aggggatgcg aacaaagaaa atcgtttgcc
     4261 aaaaatttgc tcctaccgca tgcatttctt caacaagtcg ctcatccatc gcttccattt
     4321 cttctgtaaa aagtttgcca agcattccga tctgatggac gccaatcgcc ataacaccag
     4381 caaaggggcc aggtccgacg actttcacaa aaataattgc aaaaactagt tcaggaaaag
     4441 ctcgtaaaac attacagata agcttgccaa tttttgttac ccatggatgt gcttgccaga
     4501 ggttaaccgc actgatcaag gtaatgggaa tcgctaatac cgtagcgatc attgtcccta
     4561 aacaggcgat tccaatggtt aataatagca aactaatcaa atcctcgccg ctgccatcat
     4621 atagaaactg ccaatcaggc tgacctaacc ctctcaaaac gtccattccc atggaaggag
     4681 agaaggtgct taatccagag taatccagag tagcggccga caaaataacg agaatcacta
     4741 aagcaactaa tgataaaagg gttcttctgt tcatttcacg aagcatcata acagggacct
     4801 cctgacacgt tcacttaatt tatcaacgat cgcgacagtt actaggatcg ttagaataat
     4861 gattgaaact cgttcataat tcaaaagcgc aagtgaggaa tttagaataa cgccaatacc
     4921 accagctccg acatatccaa ggacagtaga agcacgaaca ttcacctcaa acgcgtaaaa
     4981 agcatagctc gcaaactgac tcaaaacttg tggagcgatc gaccaaatag cgatttgcat
     5041 tttatttgct ccaacagccg cagcggcttc aatcgggcca aagtcaatgg tttcaattgc
     5101 ttgaaacatt aattgtgaca ccataccaaa agtaaagaca gcgatagtca acacgccagt
     5161 cgcttcacca attccaaaca cagcaacaaa aagcgcggct aaaagcaggg tagggatggt
     5221 ccgtactaaa cctaaaagaa aacgaaagat ggtagaaaga agacggtttt ctgtcactac
     5281 agtggtcgct aaaaaactaa cagggatcgc taaaattaag ccaatgaccg ttccaagcaa
     5341 agacatttga agtgttttca ccataggctc gactaattta ggtaaatagc taaagtctgg
     5401 atgaatgaag cgtgataaaa agacagtcat ttgattggag ttttgaaaaa cctgagaaaa
     5461 atcagctgac gtgatccagg cacttccttg aaaacaaaca attaagaaca gaagaataag
     5521 caggtgttta taccatttaa agtgaacggt ttctttcaag ctcatcgatt tcgcctgcct
     5581 tttcttcaaa gattgcattg ccataaattt gctctaagcg ttcatcggtt aagtcgtctg
     5641 gacgaccatc aaagacaacc tgagcagctt ttaacgcgag cacacgcgta gaaaactcac
     5701 gagccagagg gactgaatgc agattgacaa tgactgtttt atccatcgtt tgattgatat
     5761 tttttaggtc catcataacc ttttgagtcg tgattggatc taatgatgca acgggttcat
     5821 ccgctaaaat aatgggggct tgctgcacga gtgctcgcgc aatggatact cgctgttgtt
     5881 gcccaccact gagctcatca ctgcgtgtct gcaatttatc agacaaacca actttttcca
     5941 gtgcttcctt tgtctgctgg tagtcttcct tcgtaaaaag acctaaaata cttttccaag
     6001 tggagtaata gcccaaacgt ccagatagca catttttctg aaccgtacta cgctttacca
     6061 gattgaagct ttgcgagatt agaccaatct ggcggcgaat ctgtcgcagc tcttttttat
     6121 tcgcttttgt aatagaggtt ccattaatgc gaatatctcc tttggtggtt tctgccaagc
     6181 gattgatact gcgcagcaga gtgctctttc cagcaccact caaccctatg atggaaacaa
     6241 attctccatc ttcaattgtt aagtcaatat ccttcaagcc aacaacgcca ttgggataga
     6301 ccttcgaaac attgtcaaaa ataatcatta tccttctcca tttttttaag tgtaagcaaa
     6361 aaaaagcttg ctgacactta ctgatgtttt attctgctgc ttttttcgtg tagtctctga
     6421 tcgtgtcata ggcagaatca gcagcttctt catagccctg atgcccccac aaagccattg
     6481 cttctttgcc atctttatca tccttcatat ttaagaaggt ctctttaatt ttcgctttta
     6541 aatcttttga catgtcaggc tgtacagcga ttgcgtcatt cggaatatcg ccttttgtca
     6601 ggtacaggac ttttaaatcc ttaaataaat cattatctgg gaaattcgaa gcaaaaacat
     6661 ttcgcgcgcc ttcaaaaaca aacgccgcat ccatttgctt gttcaacact gcggtaatct
     6721 cactcggaat atcattcaca gtggtcatct ttgtatctgc agtaggatca atcccagcat
     6781 ctttcaattc agcgacagga tagatgtagc cgctagcaga gttaggactt aaggttgcga
     6841 tattttttcc ttttaaatca gttaacttat tcaatccgct atcggcacga accaatactt
     6901 ctcctttaaa ggtgttcgta agtttgtcct ttaatggcaa gccagtttct tgatcataat
     6961 cgccgagctg agaagtcagg attgcatctg cagctccagc atcctttgct tgaacatagg
     7021 ctgcaggcgg cataattccg acatcgactt gaccagaaga catcgcttcg acgatcgttg
     7081 aataatcagt agctaacgtc acttctacct cacgatctaa ctttttcgat aaatacttag
     7141 caaatggttt tgcttttgcc tccatactac catcattgtt tgttggaacg aattgaacaa
     7201 ctaatttttc tttgctctct ttttctgagc tgctacttgt attcccagaa ccgcaggccg
     7261 ccaaagtggt caataacatg actccgatga acccttttgc taactgtttg aactgcattt
     7321 ttctcctcct gttggatata atttctaata cgtctaaatc atagcaggga atcaaaatca
     7381 atgaagtgac gcacgtccta ttttacacaa cttttacata caatttacaa acaattataa
     7441 ataattattc gtattgagcc gaaaaacaat ctaagctata ataaagaaaa acttcttaga
     7501 ggtgacgatt tcatgaaaaa aatccatgat acgaagcaat taactgctta cgttgagaag
     7561 cacaacctgc aggattatat ggattcagat atattggcaa tggcttcttt actttttttt
     7621 gaaaaggaag agcacctcat tcaaacggga aaaacctcag attatttgta ttttttagtg
     7681 gatgggacgg taatggtgta ctcgtattct tctgatacac aaaatatttg catcgattac
     7741 gcaaagcccg ctacaccact cggcgaagcc tcttcattgt gggaattatc gccgaaaagc
     7801 agcgttaaag cagtgactaa gtgcatctgt atcagcattc cgctaaatca atatcgaaca
     7861 cagcttcaaa aagatgttcg ctttttgcag aatatttgcc agttactaag ttatcgttta
     7921 aattccggga taaatttggc gaactcactg acagaacctg ttgaaactcg tttagcaaag
     7981 tttattttga cccatcacga aaacgaacgt ttctcatttc ggttaaccac ctgcgcctca
     8041 atcttaaatg tcagttatcg acatctttta cgaacaatca cgaattttcg tgaggagaat
     8101 attatcgaaa agaaaaagaa ttattacttg attcatgata tcgaagcttt agaggactta
     8161 gctgagaata taagtagtcc agtaaaagca gaataacagc tataaaaaaa cagcagtcag
     8221 aagtgattgc tggttttttg atagtggaga aattgggaaa cggaaaatct tcgttgaaga
     8281 gtagtgttct atatattggt atgctatact tttaaaagtt caatgtgtca agacacataa
     8341 aaaggggaga aaaattttga agaaaatact tgtttcattg ttgtttttgg tgtcattagt
     8401 aacgttagtc ggctgtagtc agtctcaggg ggagaagcaa agtgaaaaag agaaaagtaa
     8461 aatcgctttg gttcttggat ttggcggggt tgatgaccgc tccttcaatc aagctggctg
     8521 ggaaggatta gaggcttggg gaaaagagaa aaagctgaca gcaaaaaaag attttacgta
     8581 tatagaaacg aacaatccag aggataacag taccaatatc gatcaggcaa tcagaaacgg
     8641 ctttaccacc attattagct tgagctactt gcaagcagag gaactggaaa atgctgctaa
     8701 agataatcca aagttgaaat ttgccttggt agatggtgag attactggga aaaagaatat
     8761 ctcatcagca acctttaaag atcaagaaag tgcgtattta gcaggactag ctgccgcata
     8821 tacgacaaaa agtgatcaag taggctttat tggtggaatg gaagggcccg tgatccaacg
     8881 tttccaaagc ggatttgaag ctggcgttaa ggcaggggcc acagcactga acaaggaaat
     8941 tactgttaac gtacaatatg ctgcatccta tgattcgcta gataaaggaa aagctattgc
     9001 tgcttctatg tacaaagagg gagtcgatat tctttatcag gcggcaggaa gtactggagc
     9061 tggggtgttc caagaagcaa aagcccgcaa tgaaaacgac tatagcagaa aagtatgggt
     9121 gattggtgta gatcgcgatc aagcggatga aggggattat aaaatggaga acggcgagac
     9181 agggaatttc acgttgactt ctacaaagaa aaatgtcggt gcagaagtca aagaatttgc
     9241 agaaacttct cataacgata aatttcctgg cggcaagcat ttgacctttg gtttgaaaga
     9301 agaaggggta gatctgacaa aaggacaatt atcagaggaa gcctatcagg cagtttcaga
     9361 cgcaaaagag aaaatcatca gtggtgattt cagactgtag acaaagtcca ttttatggat
     9421 gatgtctaca gt
//
LOCUS       DADGKS010000091         9384 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.094, whole genome shotgun sequence.
ACCESSION   DADGKS010000091 DADGKS010000000
VERSION     DADGKS010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9384
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.094"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..1879)
                     /gene="rpoC"
                     /locus_tag="JXV47_002501"
     CDS             complement(<1..1879)
                     /gene="rpoC"
                     /locus_tag="JXV47_002501"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HAX1488511.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AE"
     gene            complement(1958..5575)
                     /gene="rpoB"
                     /locus_tag="JXV47_002502"
     CDS             complement(1958..5575)
                     /gene="rpoB"
                     /locus_tag="JXV47_002502"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAX1488512.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            6303..7271
                     /locus_tag="JXV47_002503"
     CDS             6303..7271
                     /locus_tag="JXV47_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAX1488513.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            7289..8194
                     /locus_tag="JXV47_002504"
     CDS             7289..8194
                     /locus_tag="JXV47_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1488514.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            8191..8997
                     /locus_tag="JXV47_002505"
     CDS             8191..8997
                     /locus_tag="JXV47_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAX1488515.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            9154..>9384
                     /locus_tag="JXV47_002506"
     CDS             9154..>9384
                     /locus_tag="JXV47_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAX1488516.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIP"
BASE COUNT         2595 a         2057 c         1883 g         2849 t
ORIGIN      
        1 cttctgcgat gatgtttcct aagtttttct tcttgaacgg taatactaat tcttgctctt
       61 tgatatgtgc aggaatatca gtaccagctt caacaaagta tttgtccggt gtttggacgg
      121 tcaagttgaa gtctgttggt tcattcagat aagggaattc aggaggcatg atctcgttga
      181 agatgatctt accaactgtt gtgatcatcg tacgttcttt ttgccattca gtaaatggtt
      241 tttcacctaa tgagttaggg ttcacaccga tacgtgaatg taaatgaaca tatccgttgc
      301 gccatgcgat aacggcttcg ttttgatctc tgaagaccat tccttcgcct tcgcgtcctt
      361 cttcttccat tgtcaagtag tagttaccta gaaccatatc ttgagaagga gtaacaactg
      421 gtttaccatc tttagggttc aagatgtttt gagcagctaa catcaacata cgtgcttctg
      481 cttgtgcttc ttcattcaat ggaacgtgga cagccatttg gtctccatcg aaatcggcat
      541 tataagcttc acatacaagt ggatgcaaac ggattgcgcg tccttgtact aaaactggtt
      601 cgaatgcttg gataccaagt cggtgaagcg taggtgcccg gttcagcaat actgggtgtt
      661 ccttgattac gtcttctaaa acatcccata cttcgtcttc ttgacgttcg attttacgtt
      721 tcgcattttt gatgtttgaa gctagttcgc gttgaacaag ctcacgcatc acgaatggtt
      781 tgaataattc aatggccatt tcttttggaa gtccacattg gtacatcttc aagaaaggtc
      841 caacaacgat aacggaacga cctgagtagt cgacacgttt acctagcaag ttttgacgga
      901 aacgaccttg tttccctttc aacatatgag aaagagattt caatgggcgg ttacctggtc
      961 cagtaactgg acgtccgcga cgaccgttat cgatcaatgc atctactgct tcttgcagca
     1021 tacgtttttc attttgaacg atgattccag gtgcattcaa gtctaacaaa cgtttcaaac
     1081 ggttattacg gttgattaca cgacggtaaa gatcattcaa gtcacttgtt gcaaaacgtc
     1141 caccttctaa ttgaaccatt gggcgtaaat ctggtggaat aacagggata acgtccataa
     1201 ccatccagct tggttgattt cctgaagcgc ggaatgcttc taaaatatcc aaacggcgga
     1261 ttgcacgtgt acgtttttgt ccttgtgcag atttcaattc ttctttcaat tcggctgctt
     1321 ctgcatctag atcaacatta tcaagtaatt gtttaatcgc ttctgcaccc atagcagctt
     1381 ggaattcttg tccatattgt tcacgttttt cgcgatattc gcgttctgtc aacaattgtt
     1441 ttttctctaa attcgtattt cctggttcga tgactacata tgaagcaaaa taaatgattt
     1501 cttccaaagc gcgtgggctc atgtctaata caagacccat acgtgaagga atccctttaa
     1561 agtaccagat atgtgaaaca ggagctgcta attcaatatg tcccatgcgt tcacggcgaa
     1621 ctttcgaacg agtaacttcc actccgcatc gatcacaaac gattccttta taacggatac
     1681 gtttgtattt tccgcaggca cattcccagt cttttgtagg accaaaaatc cgctcacaga
     1741 acaacccttc gcgttcaggt tttaaggtac gatagttaat cgtctcaggt ttttttactt
     1801 caccgtaaga ccagcttctg attttttcgg gagaagccaa acctatttgc atactttcga
     1861 atttatttac atcgatcaaa aggggttccc tccatttcat ttaatggcaa accgcaagac
     1921 ggctgatctt cgaccgcctt gcagctcata gaccggatta gtctaaatta tcttctgcgg
     1981 tttcaaagtt ttggatgaca tcgtcttttt catcttccac ttgttcagca gctttctttt
     2041 ctaattcttt ggcagtttgc tgttcggcaa attttgtcaa agcatcaaca gtgatcaaat
     2101 cgtcgtcttc atcgtccatg tcgcgaagtt cgatctctgt ttcttcgata tccaagacac
     2161 gcatgtccag acctagtgat tgcaattctt tcaccaatac gcggaatgat tccggtacac
     2221 ctggttttgg aattggttca cccttgacga ttgcttcgta tgttttcaca cgtccgacta
     2281 cgtcatctga tttgtatgtc aagatttctt gtaaagtata agccgcaccg taagcttcca
     2341 gtgcccatac ttccatttca ccaaaacgtt gtccaccaaa ttgagcttta cctcccaatg
     2401 gttgttgtgt aaccaatgag taaggtccga ttgaacgtgc atgcaatttg tcatcgacca
     2461 tgtgagcaag tttgatcatg tacatcacac cgacagacac acgtccatca aatggttcac
     2521 ctgtacgtcc gtcgtacaga acagttttcg catcgctggc cataccggct tcacgaactg
     2581 tttcccatac gtcttcatca cttgcaccat caaatactgg cgttgctacg tggataccta
     2641 actgacgtgc agccataccc aagtgtaatt ccaatacttg cccgatgttc atacgtgaag
     2701 gcacccctaa aggattcagc atgatatcga ttggtgttcc atcaggtagg aatggcatat
     2761 cttcttccgg cataatacgg gatacaaccc ctttatttcc gtgacgaccg gccattttat
     2821 ccccttcatg gattttacgt ttttgaacga tataaacacg aactaacatg tttacgcctg
     2881 gtgacaattc atctccagct tcacgagtaa agattttcac atcgtgaacg ataccgccgc
     2941 cgccatgtgg tacacgtaat gatgtatcgc ggacttcacg agctttttcg ccaaagatcg
     3001 catgcaatag acgttcttct gcagataatt ctgttacccc ttttggcgtg actttcccta
     3061 caagcaaatc gccatcttgg acttctgcac caatacggat gatacccatt tcgtctaaat
     3121 cttttaatgc gtcttccccg acattaggga tttcgcgtgt gatttcttca ggtcctaatt
     3181 ttgtatcgcg ggcttctgat tcatattctt caatatggat agaagtgtat acgtcatctt
     3241 ttaccaaacg acggctcatg atgatcgcat cttcatagtt gtacccttcc caagtcatga
     3301 aaccaactaa aacgttttgg cctagagcca tttcgccttg ttccatagat ggtccgtctg
     3361 ccagagtatc ccctttttcg actttctcac ccaaatgaac gattggacgt tggttgtagc
     3421 ttgttccgga gtttgaacga cggaattttg ttacatcgta tttatctaat gcaccgttgt
     3481 cgcggcgtac gcggatttca gaagcatcaa cgtattcaac gacaccgtca tgtttacata
     3541 acaaagcagc tcctgagtca tgcgctgatt tgtattccat accagtacca acccatggtg
     3601 cttgaggatt gatcaacggc actgcttgac gctgcatgtt ggcacccatc aaggcacggt
     3661 tggagtcatc gttttccaag aaaggaatac atgctgtcgc aacggcaact acttgtttag
     3721 gtgatacgtc catgtagtct actttatcaa tagatacttc taagttttca ctttgagcac
     3781 gagccataac aacgtcttga gcaaatgttc catcttcatt caatgggctg tttgcttggg
     3841 ctacgatgta atggtcttcg atatcagctg tcaagtagtc gatttggtca gtaacacgac
     3901 ctgtttcacg gtctacacga cgataaggtg tttcgataaa tccgaattta tttactttcg
     3961 cataactgga caaactattg atcaacccga tgtttgggcc ttcaggagtt tcgatcggac
     4021 acatacggcc atagtgggag tagtgaacgt cacgaacttc ataaccggcg cggtcacgag
     4081 tcaatccgcc aggtcctaag gctgaaagac gacgtttgtg tgtcaattcg ccaagagggt
     4141 ttgtttgatc catgaactgt gacaactgag aagaaccaaa gaattctttg atacttgcca
     4201 caactggacg gatattgatc aattgttgag gtgtcaatgt ttcagtatct tggatcgaca
     4261 ttctttcacg aaccacacgt tccatacgtg ctagcccgat acggaattgg ttttgtaaaa
     4321 gttcaccgac tgaacggata cgacgatttc ctaagtggtc gatatcatcg acattgccga
     4381 taccttccat caagttcaag aaatagctca ttgaagcaat gatgtcggct ggacgaaccg
     4441 tttttacagc tgcttctgga tagccgtttc cgatcacgtt tacttcacgt tcagggtctc
     4501 ttggtgaaaa tactttgatg acttggacag tcattggatc tgtgaccaca ccgtcttctg
     4561 atggatagta agtcactgaa tttaggccat tatcaatgaa aggagctagt gtttccatga
     4621 cttggtgagt cagaactgtt cctttttcaa cgatgatctc gcctgtttct ggatcaacta
     4681 atgtttcagc taatgtcaga ttcaatagac gtgttttcaa atctaatttt ttgtttactt
     4741 tgtaacgacc aacgtttgct aagtcgtaac gttttggatc gaagaaacga gcattcagca
     4801 agttacgtga gctgtctgct gtttttggtt cgcctggacg caaacgttcg taaacgtctt
     4861 tcaaaccttc ttctgttctt gagtcgcttg cgtttttatg caagtctttt tcgactgtat
     4921 tgcgtaatgt ttcgctgtcg ccgaagattt caaagatcgt atcatcggaa ccaaatccta
     4981 acgcacgaac taatacggtt aaaggaatct tacgtgtacg gtcgatacgt acataagaga
     5041 tgtcttttgc atcagtttcc atttctagcc aagctccacg gttagggata acagtagaac
     5101 cgaatccttc ttttccgttt ttgtcgactt ttccatggaa atagacacct ggtgaacgga
     5161 ctaactgaga aacgattact cgctctgccc cgttgatgat gaatgttcct tgttctgtca
     5221 ttaatgggaa atcaccgaag aatacttctt gtgctttgat ttcgccagtc tcgcggtttg
     5281 tcaaacgcaa tgttacatgt aatggtgcag agtagtttgc atcatgcgca cgagcttctg
     5341 ctactgtata ctttggttct ttcaattcat aatctacaaa ttccaaagat agattgccat
     5401 tgaagtcatc gattggcaaa atgtcttcaa acatttctct aagtccctca tctaagaacc
     5461 attggtaaga gtctgtttga atttcgatca aatttggtaa ttccaacact tcactgattc
     5521 ttgcgaaact tctacgttcg cgatgttttc cgtattttac tacgtgtcca gccaagctct
     5581 tcacccctct aaaatgtcat tcaaaaagac tacccgatca attgttacaa taatatttca
     5641 aatattattt ttaggtaaca acagacattt tttgcggctt ttaggcaaaa aaaaaccaaa
     5701 aatagaacat tctcttgaaa ccttacttcg tgagcttcta cttttgtttc cttatattaa
     5761 agccgaaacg gacaatattt cgtttctgcc ttttcttcat cagatagttt ttgcaacttc
     5821 atatactaca cttattttct ataaaagtca acacttcctg gcgtttcttc tgctttttcg
     5881 caacattttc ttaatgtttt caattttatg ttttcaatta tctgacaatt cttaattgac
     5941 agaccttttt atctcggtta tactttagaa aattcatttt gtggaggaac ttctatgcga
     6001 accaacatca accaaatcgc accaacacaa ctgaataact tttactttag ctactttaga
     6061 taggtttgta ttcatcatga tggatacaaa cgttaaacga cagtttgtat ctatgatggc
     6121 taaagaactt tgtattgcag caaaaagcca cgtagacaaa atgctaagtg gctgagcagt
     6181 gaaaatacaa agtaaaagta tcaagcattc tactttttca atttattttc cgacttttca
     6241 atccatttgg acattttgtc tgaatggatt ttttgtttcc caaaattaag gaggaaaaag
     6301 aaatgaaaaa aaatataatc atcggattag gcgctgccct gctactagct ttaggaggtt
     6361 gcgcacaaaa agacaattcc gcagaggcat cagatggaca aaaaacaatt ggcgtattgc
     6421 aacttgtaca acataactcg ttagatgctg cctataaagg attcaaagaa ggattagcag
     6481 aagaagggta taaagaaggc gataatctaa caatcgatta tcaaaatgcc caaaacaatc
     6541 aagacaacct gaaaagtatg agtgagaaac tcgtcaaaga agatcctgat ttgctacttg
     6601 gaatcgccac tccagcagca caatctttat taaatgaaac aaccactatc ccgatgactg
     6661 tcacagcggt cacagacttg gaacaagccc atttagtcac atccaatgaa aaacctggcg
     6721 gcaatgtgac tggcacgaca gatatggtgc caatcgaaaa acaaatcggc ttactgttaa
     6781 atatcgtgcc agacgccaaa acaatcggca tcatgtataa caacggtgaa gcaaactcta
     6841 agatccaagc tgatttggca gaaaaagaat tgaaaaaagc gggcgtcaaa gtcaaagtac
     6901 tgacagcaaa ttccacaaat gatgtccaac aagtgacgaa aagtctagct aaagatgtag
     6961 atggaatcta tattcctact gataacacgt tcgcaagtgc ggcaagtgtt gtcggtgaag
     7021 tcgcaaaaga aacaaaaaca cctgtcgttg ctggcgcagt tgatcaagtc aaagacggcg
     7081 gtctagcaac agtaggaatc gactacgaaa gcttgggcaa acaaacaggg atcatggcag
     7141 caaaaatctt agacggcaag aatccaagtg aacttcctgt cgaaacagcg aatgatttgg
     7201 aactgtatgt caataaagac atggccaaag cattaggcat caatccagac agcatcaaag
     7261 aagctgaata aaacacagga ggattctcat gacaaatttg ctctctcttt tcttatcatc
     7321 tgcatcgcaa ggggtcttat gggccctact tgcgattggt gtatacgtca ctttccgtat
     7381 cttggacatt gccgacttga ctgctgaagg aagctttcct ttaggtgcag ggatcgcggc
     7441 agtaagtatt acaaatggct atcatccatt gacagcttgt cttctaggct ttttaggggg
     7501 tgcggcagca gggcttgttt ccggactgct tcacacaaaa ttgaaaattc ccgcccttct
     7561 tgcagggatc atcaccatga ctggtttata ttctgtcaca tcccgtgtga tgggtgcgcc
     7621 gaacatctct ttattgggtc agccaacgat ctttcattgg gtcgagtcat tcggcataac
     7681 aaaagacaac gctgtactga tcgtcggtct gctttttgct ttgatcgttg tatgtttact
     7741 tgttttgttc ttacgtacag aaacaggact tgctattcgt gcaactggcg ataatctggc
     7801 aatgagcgaa gcaaacggga tcaacacaga taatatgaag atcatcggtt atatgatttc
     7861 taatggatgc attgctcttt ctggctcctt acttgcgcaa aacaacggct ttgctgattt
     7921 aaattctggt attggaacga tcgtaattgg acttgcttct attatcatcg cagaagtttt
     7981 gttacgtaac cagccactat ttctccgtct cttgactgtc gttttaggtg cggtcattta
     8041 tcgttttatt ttagcgttag tcttcgaact gaatgttgaa ccaagtgatt cgaaacttgc
     8101 ttctgctttc gtgctagtga tctgtctttc tttcccgcag atccagcaaa aattccattt
     8161 acctcaaaaa aagaaaggcg gtagtgtcaa atgaatgacg tcttaacatt ggaaaatctc
     8221 catcatacct ttgaaaaagg aacgatcaac gaaaatcatg tcctgaaagg cattaatctt
     8281 tccttagatc ccggcgactt cgtgacgatc atcggtggaa atggggctgg taaatctact
     8341 ttgctgaaca gcatcgccgg tacattttct gtcgatcagg gtcaaatttt attgaatgga
     8401 aaaaatatca cgaaaaaatc tgttgtcgaa cgttcgaaat ccatcagtcg cgtattccaa
     8461 gatcctaaac tagggacagc cgttcgttta acggtagaag aaaatcttgc tcttgctatg
     8521 aaacgaggaa aaaaacgcgg cttcttccgt ggtgtcaaac cacaagaccg aacatttttc
     8581 aaagaccagc tggttcggct aaatttgggg ttggaaaatc gtttatcctc agaaatcggt
     8641 ttgctgtctg gaggacaacg tcaagctatt acgttattga tggccacatt acagcgtcca
     8701 gaactgatct tattagatga acacactgca gcgcttgacc ctgctacttc caaaacggtg
     8761 atggaattga cagaaaagct gatcactgag cagaatctca ctgcttttat ggtcactcat
     8821 gacatggaag acgcgatccg ctatgggagt cgactgatca tgctgcatca aggaaggatc
     8881 gtcgtagata tccagcaaga ggaaaaacag cagctcacag tgccccaatt attagcgttg
     8941 ttcaaacaaa acagcggcac ggcattaaaa gacgatcaag tacttttatc ttcataatca
     9001 gaaagaggat gggacaaaaa atgaacgccc accctcttct tttttctctt tccttctttc
     9061 gtttttgctt tatgtatcaa ccgttgtttc ttcgaaaact attttgttct ctccttcttc
     9121 ctgatagaat ggatgggaaa ggagcttgat gccatgacaa cgaaagacaa ggtacttcaa
     9181 ttattgaaaa agacaccaga ttttctttcc ggagaaaagt tggcacagca actggaagtt
     9241 tcccggacaa gtatttggaa agccatcaaa gaattggaaa aggcaggcta tcgttttgag
     9301 cacgggccta cagggtatcg ttacctgccc tctgacgtac tagatgcaaa agaaatccag
     9361 caagagctac ggtcgtttat tcct
//
LOCUS       DADGKS010000092         9086 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.096, whole genome shotgun sequence.
ACCESSION   DADGKS010000092 DADGKS010000000
VERSION     DADGKS010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9086
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.096"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..282)
                     /locus_tag="JXV47_002507"
     CDS             complement(<1..282)
                     /locus_tag="JXV47_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAX1488517.1"
                     /translation="MSITKNIKCTDEKTSHSIKQILNIKDSHITFSKDAISKERVHGR
                     MANVFTGLLTGEAHRCECCGFDSVIRHAYHDSWIQLLPYQEVPTYLHLYK"
     gene            complement(430..988)
                     /locus_tag="JXV47_002508"
                     /pseudo
     CDS             complement(430..988)
                     /locus_tag="JXV47_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302360.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1157..3268
                     /locus_tag="JXV47_002509"
     CDS             1157..3268
                     /locus_tag="JXV47_002509"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012579.1,HMM:NF013070.1,HMM:NF019826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAX1488518.1"
                     /translation="MNTKDLKLLETIVRSHVTNSQQLKSLVHFSTRQITYSIKKINDE
                     LSLHGLSLIKRSNSGEWLYEANDLQKLLIYMNQAMVFKEGAIPEYINDDLAYSEIRRY
                     SELLFILANPKKVTTQEIMAFIGISKNTARNDFSKIKKELPPDYTLIFDPQNGYMIES
                     SMAKLHTLLLEVFNYLFERHATVNRFESLFSEEREFVGFFIHTYEQTFKLKFSDNSLT
                     KLYYLIGLSLSSFKRRTKGQIDFSYDLQELDEFQMIRSCIDQHYQHAEIAIDYEWLTL
                     LFLSFNTISNEFEILDSRIYQVIMEMITLFQSKSAIRISNKEELTNRLMNHLRPAIYR
                     IRYELPFEIDDLAEIVKENHEVSAVLNFVKESIVPLEAFLRKTIPETELYLISVYFCS
                     ELLNSSIIETPVRKKAIVVCSNGLIMANVMAKTLKEIFPDIQFVASSSVREMDKFVED
                     VDLIFSNQPLKSEIPLYIIQPIMNEEEKNRLRNRVLIDFSTNNISKETRNLTEIIKRY
                     SAVQNEESLQTDIERFLINYANSLIYLDRQSKQAQKISFVELLVSEGIILVSTKQLTW
                     QNAMELSCQPLLKEQVINQNYQTILMSQMADEEAYYFLNNRIAIPHSSPENGVIKGGC
                     SLLISVDPIIFPGNRPIHFISPFAIGKKENYLLAINQLLQLSKDEEYQQEILLCTTED
                     EVRKKIKNFLRRKQYVNNEFS"
     gene            3246..3896
                     /locus_tag="JXV47_002510"
     CDS             3246..3896
                     /locus_tag="JXV47_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HAX1488519.1"
                     /translation="MSITNFPELTIILRGYSFEEAMFVMEELAAMNTSVGIEVTTNND
                     DFARIITEGNKKFGQQLLIGAGTVLTFSQADQAIAGGAKFLLGPKKFSTPIFSLAKER
                     GVVTVPSAFTPSEIQVMFDEGADIVKVFPAVTVGPTYFKQLAGPFGIRPLMAVGGVTI
                     DNIAAFKKAGVVYFGVGSSMFQKADIQNRNGQAIRKSIQSYLDKLAEAGSEEDESH"
     gene            3883..4335
                     /locus_tag="JXV47_002511"
     CDS             3883..4335
                     /locus_tag="JXV47_002511"
                     /inference="COORDINATES: protein motif:HMM:NF012579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAX1488520.1"
                     /translation="MSLIKLEEKNILLNQSFSNQEEYFQKITKKLMTENMVKEGYLES
                     ITKRETTYPTGLYIGERSIAIPHTDYQLSNVTAILVSVLKDSLHFQRMDDPEEMVSVN
                     VIIHLLFDSPDKQPQLLKELMSKVTNQDFLQAIMEAKSKTEVLTAFNQ"
     gene            4352..4657
                     /locus_tag="JXV47_002512"
     CDS             4352..4657
                     /locus_tag="JXV47_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIB"
                     /protein_id="HAX1488521.1"
                     /translation="MSKKTIIVACASSMITSTMAANKIRKIAKTNGLPEPRILQLKFS
                     EVAGALESNQVDFIVPTGKLQENVTKGIKVIPGTPFVTGVNEEKSESLVLEALKELD"
     gene            4669..5946
                     /locus_tag="JXV47_002513"
     CDS             4669..5946
                     /locus_tag="JXV47_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010492829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS maltose transporter subunit IIABC"
                     /protein_id="HAX1488522.1"
                     /translation="MNIVIDALNWISSLGPMIMMPIIILILGLFFRIKLNTLLKSALT
                     VGIGFAGVNIIINWFISQVGPSVQLMVKNWGIQTSIMDVGWPARAAATWSFPLAAVMV
                     FIILGINVLMLIFKKTNTVMVDFWSYNHYIFVAALVYYATDKNIILAVIFGAIDAIIS
                     FKLADWTTPLVEDYFELEGVNFPTANSVGWAPLAWLLNKLWDRIPGLNKVDARPEKIQ
                     ERFGFVGEPMFMGFVIGLVIGLLAKEPVDKVLILGMSTSATMVLTPKMMQILMEGLLP
                     FANSVKKFLNVKFPGNNFTMGVDAALTVANSSAIATGIIMVPITLVLAAILPGNKLLP
                     ISDIAYQAMWLSAWPVAFSKGNIIRGILSTTIITACVLLIATSLAGIHTQLALAGGFQ
                     LPAGMTQISTEDAGTHIIGFILMKIAEFISNIF"
     gene            5965..7113
                     /gene="dgoD"
                     /locus_tag="JXV47_002514"
     CDS             5965..7113
                     /gene="dgoD"
                     /locus_tag="JXV47_002514"
                     /EC_number="4.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactonate dehydratase"
                     /protein_id="HAX1488523.1"
                     /translation="MKISKITVYKVKPRWIFVKISTDEGIEGWGEMISGTKTETVVAG
                     AYEIGNRFLVGQNPFAIERLFQEMHRSFFRGGPINGTIVSGLEMALWDIKGKALNVPV
                     YELLGGAARDKIKVYSWIGGDRPSEVVEQAQDRVDRGFTAVKMNATEELHYIDSYEKV
                     AEVVERVASIRERFGDTLSIGVDFHGRVHKPMAKVLAKALEPYHPMFLEEVVLPENEE
                     HFSEVANAVAVPLATGERLYTRWQFKSILQQGAIDIIQPDVALCGGILETRKIAAMAE
                     AYDIAVAPHAPYGPIALAATLQVDSCTPNVFIQEQSLGIHYNKGFDLLDFVKNKEIFQ
                     YKDGFVDLPTKPGLGLEMDEDRVKEIAQEGLVWTNPKWKNYDGTIAEW"
     gene            7125..8027
                     /locus_tag="JXV47_002515"
     CDS             7125..8027
                     /locus_tag="JXV47_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aryldialkylphosphatase"
                     /protein_id="HAX1488524.1"
                     /translation="MINTVTGPIEAESLGTTFIHEHLYVIPNELRKYEDYTLDDIYHS
                     IAEVMAFKQAGGKTIVDLTPINYGRNPLALKMISEATGVNVAFVTGFHKEEFQPKWLT
                     TLNDDEIFELLYSEITHGVTSQNLLPGAMKVGTSKNEVTLAEQRILAIAGQVQKKTGI
                     PIITHCDGGTMGLEQINCLTKNGAKASNICLSHVDLTKDFHYLAQICETGASICMDHI
                     GRELANHDADRVQLIKRLVDAGYENQICLSGDMGRKKYLPTYGGTPGLTYILTSLKEE
                     LLKVMSEPTFNKMIEMNPINILSK"
     gene            complement(8696..>9086)
                     /locus_tag="JXV47_002516"
     CDS             complement(8696..>9086)
                     /locus_tag="JXV47_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAX1488525.1"
                     /translation="FKQFPLFQGKYMTESEVLDYLLSIDNQLRQSYEVYQELLAAFDA
                     KDFTEFFNLIESLPHSLNDGFKKAICYLKKHTEAITNSLKYPYSNGKLEGKNNLIKVI
                     KRIAFGFRTFRHLRMRVLIQQNICEII"
BASE COUNT         2948 a         1397 c         1854 g         2887 t
ORIGIN      
        1 tttgtacagg tgtagataag ttggtacttc ttgatacgga agcaactgaa tccaactatc
       61 atgataagca tgacggatga cagaatcaaa cccacaacat tcgcaacgat gcgcttctcc
      121 agttaataag ccggtaaata cattggccat acggccatga acgcgctctt tactaatggc
      181 atcttttgaa aaggtaatat gggaatcttt gatgttcaaa atttgtttga tggaatgact
      241 tgtcttttca tccgtacatt tgatattctt agttatggac atttggttat cctcctatga
      301 ttgtttttgc cgatttaatt ataggacaac cagatgtctt tttgttataa aaaaatattt
      361 ggcgtcacta ctcagtttga gtaacaaaac caaatattat agaaccggct ttttcagttt
      421 tttcccttca caaacaacat cgatgatttt ctcggcatgg gtacgggtat cattcattaa
      481 ttctgtatcg gttggatatt tgatgttttg tggagcacaa gtggcatcca aaatcaatgt
      541 tccggaattg aaatcgtcat aagaatcgtt gtccttatcg tcttttttct tgtcgaagac
      601 gagtattttt tcattgattt ctatcaacgt tgtttcgtcc aagcgtttcc ggaaatagac
      661 cattgtagag catcgaaagg cttggcatct tgatagcccg gcaaaccgat gaagaactat
      721 aaatacgggt tttcttgaat ttgtaagacc gtttcttcgt cgctatagct atattccttt
      781 tgaatcagta gagctccgaa ggtcatgcga aagggttttg cgacgtttcc ttttttttac
      841 gaaaattttt agcgtagtct ttttcaagtt cagcccatgg aatgagctct gctttttgaa
      901 tccaacggtt agacggattc attttgagac ctatcggttg attgaaatct tcaaaagcca
      961 attgaacggt tgtttgtaat ttatacatga aaagcctcca aaattgagtg gtactccaca
     1021 ccattctgat ggtgcataag ataaaaaatt aaagaagtgc ctgtcatttg tctgatttaa
     1081 gccaaggttt gacaaatttt ggatattcca attaatactg taagcggtta tatttaactc
     1141 agggaggtag atgaatgtga atacaaaaga tttaaaactg ttagaaacca ttgtacgatc
     1201 acatgtgaca aactctcaac aattgaaatc attagtacat ttttcgacta ggcagataac
     1261 ttactctata aaaaaaatta atgatgaatt atcccttcat ggattgagtc tgataaagcg
     1321 aagtaactca ggggagtggt tatatgaagc caatgatctt caaaaacttt tgatatacat
     1381 gaatcaagca atggttttta aagaaggtgc gattcctgaa tatataaacg atgatttggc
     1441 ttatagtgag ataagaagat attcggaact gttatttatt ctagccaacc ccaaaaaagt
     1501 gacaacccaa gaaataatgg cgtttattgg tatcagtaaa aatacggcta gaaacgactt
     1561 ttctaaaata aaaaaagagt tgccaccaga ctacactttg atatttgatc cccaaaatgg
     1621 ctatatgatt gaatcaagca tggcaaagct tcatacattg ctcttagaag ttttcaatta
     1681 tttatttgaa aggcatgcaa cagttaaccg ttttgagtca ctcttttctg aagaaaggga
     1741 atttgttggt ttttttattc acacctacga acaaactttt aaattgaaat tttctgataa
     1801 ttcactaacc aaactttatt atttgatagg tttatcactt tctagtttta aaagaaggac
     1861 gaaaggacag attgatttta gttatgattt acaggaatta gatgagtttc aaatgattcg
     1921 aagctgcatt gatcaacatt atcaacatgc tgagatagct atagattatg aatggttgac
     1981 gcttctgttt ttatcattca atacaatttc aaatgagttt gaaattttag attcaagaat
     2041 ctatcaagta attatggaga tgattacctt atttcaaagt aaatcagcta ttcggattag
     2101 taataaagaa gagttgacca atcgattgat gaatcattta cgacctgcaa tctatcgaat
     2161 tcgctacgaa ttaccatttg aaatagatga tttagctgaa attgttaagg aaaaccatga
     2221 agttagtgcg gtacttaatt ttgttaaaga atccattgta cctttggaag catttttgcg
     2281 taagacgatt cctgaaactg aattatattt gatttctgtt tatttttgtt cggagctatt
     2341 aaattcttct attatcgaaa cacctgttag aaaaaaggca atcgtcgtat gtagcaatgg
     2401 attgattatg gccaatgtaa tggcgaaaac attgaaagaa atttttccag atattcagtt
     2461 tgttgctagt tcttcggtca gagagatgga taagtttgtc gaagatgttg atttgatttt
     2521 tagcaatcaa ccattgaaaa gtgaaattcc attatatatt atacaaccga ttatgaacga
     2581 agaagaaaaa aaccgcttgc ggaaccgtgt actcattgat ttttctacga ataatatcag
     2641 caaagagact aggaacctta ctgaaattat taagcgttac tctgctgttc aaaatgaaga
     2701 aagtctacaa actgatattg agagattttt aattaattat gcaaattcac taatatatct
     2761 agatcgtcaa agtaaacagg cacaaaagat atcttttgtg gaattgcttg tttctgaagg
     2821 gattattctt gtatctacga aacaacttac ttggcagaac gcgatggaat tgtcttgtca
     2881 gcctttatta aaggagcagg taattaatca gaactatcag actattttaa tgagtcaaat
     2941 ggcggatgaa gaggcttatt attttcttaa taatcgtatt gctattccac attcatcgcc
     3001 agaaaatggg gtaattaagg gcggttgctc gttacttata tcagttgatc caattatttt
     3061 tcctggaaat aggcctatcc attttatttc cccttttgca attggaaaga aggaaaatta
     3121 tttacttgcg attaaccaat tactacaact ttctaaggac gaggaatatc agcaagaaat
     3181 acttctttgc acgacggaag atgaagtgag aaaaaaaata aaaaattttt taaggaggaa
     3241 gcaatatgtc aataacgaat tttcctgaat taaccatcat tttaagagga tatagttttg
     3301 aagaggcgat gtttgtcatg gaagaattgg ctgcgatgaa cacttcggta ggaattgaag
     3361 taacaaccaa taatgatgac tttgcacgta tcatcacaga aggcaacaaa aaatttgggc
     3421 aacaattatt gattggtgca gggacagttt taacattttc acaagcagat caagcaattg
     3481 ctggtggtgc gaaattttta ttaggaccaa aaaaattttc aacaccaatt ttttcgttgg
     3541 ctaaagaacg tggggtggta actgtgccat cagcttttac gccatcggaa attcaagtta
     3601 tgtttgatga aggtgccgat attgtaaagg tttttccagc agtcactgta gggccaacct
     3661 actttaaaca actggccggt ccttttggta tacggccttt aatggcagtt ggaggagtga
     3721 cgattgataa tattgcggct tttaaaaaag caggagttgt gtactttggg gtaggatcaa
     3781 gcatgtttca aaaagctgat atacaaaacc gcaatgggca agctattcga aaatcaattc
     3841 aatcatattt agataaacta gctgaagcag gaagtgaaga agatgagtct cattaaatta
     3901 gaagaaaaaa atattttgtt aaatcaaagt ttttcaaacc aagaagaata ctttcaaaag
     3961 attacaaaga aactgatgac ggaaaacatg gtaaaggagg gatatctcga gtcaatcact
     4021 aagagagaaa caacttatcc aacggggcta tatattgggg aacgctcaat cgcaattcca
     4081 catacagatt atcagttatc aaatgttacc gctattttag tatccgttct taaagatagt
     4141 ttgcattttc agcgaatgga tgatcccgaa gaaatggttt cagtgaatgt tattattcac
     4201 cttttattcg atagtcccga taagcaaccg caattattga aggagttgat gagtaaagtt
     4261 accaatcagg atttcttaca agcaattatg gaagcaaaga gtaaaacaga agttttaact
     4321 gcatttaatc aataaattgg agggaaatac aatgagtaaa aaaacaatta tcgtcgcatg
     4381 tgcatcatca atgattacat ctacaatggc agctaataaa attcggaaaa tagcaaaaac
     4441 aaatggatta ccagaacctc gaattttgca actaaaattt tcagaagttg caggtgcttt
     4501 agaatcaaat caagttgact ttatcgttcc tacagggaaa ttacaagaaa atgtaaccaa
     4561 aggaattaaa gttatacctg gaacaccatt tgttactgga gtgaatgaag aaaaatctga
     4621 atctttggtg ttagaagcat tgaaagagct tgactaggag ggtgaaaaat gaatattgtc
     4681 attgatgcgt taaactggat ctcaagtttg ggtccgatga ttatgatgcc tatcattatc
     4741 ttgattttag gattattttt tagaattaag ctaaatacat tactaaaatc agcgttgact
     4801 gtggggattg gttttgcggg tgtaaatatt attattaatt ggtttatttc acaggtaggt
     4861 ccatctgttc agttaatggt caaaaattgg ggtattcaaa caagtattat ggatgtcggc
     4921 tggccagctc gtgcagcagc cacttggtct tttcctctag cagcagttat ggtatttatt
     4981 attttgggta ttaatgtgtt gatgctgatt tttaaaaaga ccaatacagt aatggtcgat
     5041 ttctggagtt ataatcacta tatttttgta gctgctttgg tttattatgc aacggataaa
     5101 aatattatat tggcggtaat cttcggggcg attgatgcaa ttattagttt taaactcgct
     5161 gattggacaa cgccgttagt agaggattac tttgaactag aaggggttaa tttcccgact
     5221 gcgaactcag ttggttgggc acccttggct tggctactta acaaattgtg ggaccgcatt
     5281 cctggattaa ataaggtaga tgctcgtcct gaaaaaattc aagagcggtt tggttttgtt
     5341 ggtgagccta tgtttatggg atttgtcatc ggcttggtta ttgggttatt agcaaaagaa
     5401 cctgttgata aggtattgat attgggaatg agtacttctg caacaatggt tctaacacct
     5461 aaaatgatgc aaattttaat ggaaggatta ttaccctttg ctaattctgt taagaaattc
     5521 ttgaatgtaa aatttccagg aaacaatttt acaatgggtg tggatgctgc gttgacagtt
     5581 gctaattcaa gtgccattgc tacgggtatt atcatggttc cgattacctt agtgttggct
     5641 gctattttac caggtaacaa actcttacct atttcagata ttgcctacca agcaatgtgg
     5701 ctatctgcat ggccggtcgc cttttcaaaa ggaaatatta ttcgcggaat actttccacc
     5761 acgattataa cagcttgtgt gcttttaatt gctactagtt tagccggcat acatacacaa
     5821 ttagctttgg ctgggggatt ccaattacca gcaggaatga cacaaatatc taccgaagat
     5881 gcaggtacac acattattgg tttcatttta atgaagattg ctgagtttat ttcaaatatt
     5941 ttctaatatt caggagggca tacagtgaaa atttcaaaaa ttacagtcta taaagtaaaa
     6001 ccaagatgga tttttgtcaa aatatctaca gatgaaggta ttgaaggctg gggtgaaatg
     6061 atttctggaa ctaagactga aacagttgtg gcaggagctt atgagatagg aaatcgattc
     6121 ttagttggtc aaaacccatt tgcaattgaa cgtctgtttc aggaaatgca tcgttcattt
     6181 ttccgaggtg gtcctattaa tggaacgatt gtctctggac ttgaaatggc tttatgggat
     6241 attaaaggga aagccttaaa tgttccagtt tatgaattac taggtggagc agcccgtgat
     6301 aaaatcaaag tatattcttg gattggtgga gatcgtcctt ctgaagtagt agagcaggca
     6361 caagatcgag tagatcgtgg gtttaccgcc gtgaaaatga acgcgacaga agaattacac
     6421 tacattgatt cttatgaaaa agtagctgaa gtagtggaac gtgttgcttc aattagagaa
     6481 cgttttggag atacattgag cattggtgtc gattttcatg gtcgtgttca caaaccaatg
     6541 gctaaggttt tagcaaaagc actggaaccc tatcatccaa tgttcttaga agaagtggtt
     6601 ttgccggaga atgaagaaca tttcagtgaa gtagccaatg cagttgctgt accactagca
     6661 acgggtgaac gtttgtatac aagatggcaa tttaaatcaa ttcttcaaca gggagcgatt
     6721 gatatcattc aaccagatgt agctttatgt ggagggattt tagaaacaag aaaaattgct
     6781 gcaatggctg aagcttatga tatagcagtt gccccccatg caccatatgg accgattgcg
     6841 ttagcagcta cattacaagt tgattcttgt acacctaatg tgtttattca agaacaaagc
     6901 ttaggtattc attacaacaa agggtttgat ttgttagatt ttgtaaagaa taaagagata
     6961 ttccaataca aagatggctt cgtagatctt ccgacaaaac caggtttagg gttagaaatg
     7021 gacgaagatc gagtgaaaga aattgcacaa gaaggtttag tttggaccaa tcctaagtgg
     7081 aaaaattatg atggtacaat cgctgaatgg taggagatga gtgcatgatc aatacggtta
     7141 caggcccaat cgaagctgag tctttgggta caacatttat tcatgaacat ttatatgtca
     7201 ttcctaatga gttaagaaag tatgaagatt ataccttgga tgatatttat catagtattg
     7261 cggaagttat ggcttttaaa caagctggtg gaaaaactat cgttgatttg acaccaatta
     7321 attatggacg aaatccgtta gctttgaaaa tgatatctga agctaccgga gtgaatgtag
     7381 catttgttac gggattccat aaggaagagt ttcagccaaa atggttgaca acgctcaatg
     7441 atgatgagat ctttgagttg ctttattccg aaataactca cggagtcact tcacaaaacc
     7501 ttttgccagg agcaatgaaa gtaggtacga gtaaaaatga ggttacattg gctgaacaac
     7561 gaatactagc catagccggt caagtacaaa aaaaaacagg gattcccatt attacgcatt
     7621 gtgatggggg gacgatggga ctggagcaaa ttaattgttt aacaaaaaac ggtgcgaaag
     7681 caagtaatat ttgtttgagt catgtagatt taactaaaga ttttcactat ttagctcaaa
     7741 tctgtgaaac gggagcaagt atttgtatgg atcatattgg ccgagagttg gcgaatcatg
     7801 atgcagaccg cgtccaacta attaaacgac tggttgatgc gggttatgaa aatcagattt
     7861 gtctttcagg tgatatggga cgaaaaaaat atttgccaac ttatggagga acgcctgggc
     7921 ttacctatat tttaacaagt ttgaaagaag aactattaaa agtaatgagt gaaccaactt
     7981 ttaataaaat gattgagatg aatccaatta atatactgag taagtgaagt caattgaatc
     8041 attcagaaga actaatgaaa ttagttgctt tcgcagggtt aattcttctc tctgggtttg
     8101 gaaaagaggg cttagcttcg gattccctag ttaaactagg ggttttatca ggttattgta
     8161 ctgattataa gtacctgaat tattcatgaa atactttttc cgtcgtttta taggcagttg
     8221 ggtcaataaa aagatcagaa aaacgaacga gagactctca taacgtgcca ctaaataaaa
     8281 atcgtacgtt attttaaaaa atgggttgat tctaggcagt actttgtcgg tctattttta
     8341 gaaaaagagg ttctttgtca aacatacatg aattcgcaag ctcattcacc ctgaaggatg
     8401 aaaggcagaa actgtagtat actaatggtg gaaaggaaaa aaagccgcca gcaatttgga
     8461 aaagaacgtt atgtcgattg tcaaactggc ttgctttatt tctcgagaac cctgaaatat
     8521 agccaatgag catgtgtata aaaaattgat tttatatgaa ataaagcact cctttcctaa
     8581 aattattgga aaggagtgcg ttttttatgg aaattattta ggttctttgt caattgctat
     8641 tgttttgctc aaatcgtatg ttaggaaatg cttcggcatt tccttttttg cgttattaaa
     8701 tgatttcaca gatgttctgt tgaatcagga cacgcatccg gagatgacga aaagtccgaa
     8761 atccaaaagc aattcttttg attactttga tgaggttatt ctttccctcc aattttccgt
     8821 ttgaataggg atattttaag gagtttgtga ttgcttctgt gtgctttttc agataacaaa
     8881 ttgccttttt aaacccatca ttcaaggaat gtggcaatga ttcaatgaga ttgaaaaatt
     8941 cagtaaaatc ttttgcatca aaagcagcta ataactcttg atagacttca tagctttgtc
     9001 gtagttggtt atctatagag agtaggtaat caagcacctc cgactccgtc atgtatttcc
     9061 cttggaagag gggaaattgc ttaaaa
//
LOCUS       DADGKS010000093         8879 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.097, whole genome shotgun sequence.
ACCESSION   DADGKS010000093 DADGKS010000000
VERSION     DADGKS010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8879
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.097"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(553..1533)
                     /locus_tag="JXV47_002517"
     CDS             complement(553..1533)
                     /locus_tag="JXV47_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HAX1488526.1"
                     /translation="MLFLKKEDIIKSFSMREAIDADKKALSLYSAGKASVPLRTNIDV
                     PKSNGQSLYMPAYVEGGEGALGVKIVSVYPENIKKNLPSVPATMIVLDPETGMVSACL
                     DGTYLTQLRTGAVQGAATELLAREDAKIGALIGTGGQAQSQLEAMLTVRKLEEVRIFD
                     IDFERASQFAEKMMQQFSVTMRPTKTSQECVEGADIITSVTTSKRATFSAEWVKKGAH
                     INGVGAYTPEMCEIPREIIKAADVVIFDTMDGVLKEAGDFISPLQDGYIQRDSYHGEL
                     GQLINEELIGRTSGEQITIFKTVGSAVLDVVVATEIVKKAKENNLGKLIF"
     gene            complement(1546..2424)
                     /locus_tag="JXV47_002518"
     CDS             complement(1546..2424)
                     /locus_tag="JXV47_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HAX1488527.1"
                     /translation="MIRNILLTLIVAINLYFIIYFLRDLFKNKQNFKEEPGDMRLLPF
                     TSFIIFFLSTFGVSDFAIGTVLYPKLKWVSMKKLPGTLNTQCVVPVAVMALSYITAIN
                     VGIKTLAVCIICQIIGAYLGPRFVVKLPEKTIKLFVGIGLVIAALLIFAGQMNWIPSN
                     GTASELYGGKLILAGFLLFVYGALNNIGIGSYALTMVTVYLLGLNPVAAFPIMMGACT
                     FSVPIGSVQFIKFNEYSRKITLFTSTFGVLGVLVAVFLVKSLDTYILKWIVILVLLYS
                     AYTMLGSQLKKVTAAN"
     gene            complement(2440..3240)
                     /locus_tag="JXV47_002519"
     CDS             complement(2440..3240)
                     /locus_tag="JXV47_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HAX1488528.1"
                     /translation="METIIQIMKKYDFSEMETRVYTTLLEKGNLTGYEVSKISGVPRS
                     KVYNILEKLLKKNLIVVNKSEPKLYHAISANEFLEKLEKSVKNDLSFLTKNLGMIKEK
                     DEEEMLWKVDGIEYVLDKVEHLVKNAKESLLIQVWHENFTDSLLKALQQAEKRVDKFV
                     LILFSSTHEYDLPLEKYYIHGFETDKLADFGARWINIVADEQEVVFGTINEELQSTDV
                     TWTKNHAMVNLAKEYVKHDAYTLKVIAESPEELKAKYGEGFEGIRKIY"
     gene            4632..4958
                     /locus_tag="JXV47_002520"
     CDS             4632..4958
                     /locus_tag="JXV47_002520"
                     /inference="COORDINATES: protein motif:HMM:NF013698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAX1488529.1"
                     /translation="MFKIFRKNCCGLDVHKTWIYACIGITDANGRTVYKQARFSSFTK
                     GLNELAEWLAKYNCKDVCLESSGKFWIPVFNILEKTCFVTLAHPKYTKPQKGNKTDRK
                     DAKMDL"
     gene            4966..5874
                     /locus_tag="JXV47_002521"
     CDS             4966..5874
                     /locus_tag="JXV47_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAX1488530.1"
                     /translation="MCDMIKPSFIPGLEIRQLRDLMRYRTKLTNMKTSEKNRALNCLT
                     VSNLKLDDVFSDVFGKSSTSIIQYLLEHPGESFDVRPFIHARCKTPVEEIQAAVEGAI
                     SVPQAIKLRQCLNHINEIEKHREEINLEIQALAEPFSPVLELLRTIPGLDTQPITAIA
                     ILSEIGPDMSVFPTSKHFISWAGCCPRNDRSARRTKSTRISRAGQSLKPLLVQIANAL
                     LRSKEHPEFKNRYRRIKANRGHKKAIIAICKMLLTAIWNVLSKVEPYSAKGYLEPKPA
                     KEEKVLTQSQALDLLRKRGYTIIDSA"
     gene            6503..6754
                     /locus_tag="JXV47_002522"
     CDS             6503..6754
                     /locus_tag="JXV47_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HAX1488531.1"
                     /translation="MKSNQKSGFYTFIKAISSVLECDCIIGPYSMLIKMGFPSTESLD
                     SFINDLSKFGRTNTQIVFSTLVSLMVYQFWNVYHALLLK"
     gene            7296..7454
                     /locus_tag="JXV47_002523"
     CDS             7296..7454
                     /locus_tag="JXV47_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1488532.1"
                     /translation="MNKKQACEFLGIDNNTLDKWIRVYNFPVIKIDGVVRFDVEDIKD
                     FMNTFKKN"
     gene            7526..8752
                     /locus_tag="JXV47_002524"
     CDS             7526..8752
                     /locus_tag="JXV47_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAX1488533.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGIASEKYQKVFPTRQLAIKA
                     EREMKKKIETVLREENANSLELKGKIKFKDFYESKWLPRYELGQTTRSNRAPSNVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILCYIEFNRTTKIIQCITAPKKMALEEKRIREGNQALSSEELTDWIEAVNNDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFNKNTVRLKYALDKYQRKTHTKGWKDTV
                     IQAPEVVMTLLREWKSAQAEQLLKLKIIQTPDQYLFTYSKPSGEVNCPVHADYLNYRI
                     NAIKKRHPELAQLSPHKLRHTYATIAREGGANMNQISNALTHSDISTTKIYVNTPDVV
                     DKSVFEAFQKGLNKCD"
BASE COUNT         2817 a         1695 c         1480 g         2887 t
ORIGIN      
        1 tctttcagga agacttcggt aatttttagg agttctacct attcttttaa ccgtttattc
       61 tctttttcta agcgtgtaat ttcatttctg cgaatggatt tcatgacttc ctctaccgag
      121 aaaagtacgt tatccatatt tttcaacttc ttgaactcat caatacacgc tattagagcg
      181 agcttctagc tatagactaa cttctttaac agaaaaccct tcttccgtta ccagttttac
      241 agcggtaatt ttaaatattt catcaaatga acgtcttggc ataatccaga tcttcgcttt
      301 ctcttaattt ggtgtcaatt ttagtataac ccgtccaact tattttttaa ctaagtgccc
      361 ggtttttctt gacaactcca cccaaaagtt agattttttg gtctaagttt tagggtcgct
      421 tcattactag aattcaacaa gagatgtttt ttattttatt taaattatgg ggtcagtttc
      481 catttgatta caaacttctt tgttttcttt ttttaaacgc aataataaag gttttaattt
      541 cagccttttt aattagaaaa tcaattttcc caaattattt tctttagctt tcttaacgat
      601 ttctgtcgca actaccacat ctaatacagc cgaaccaact gttttgaaga tcgtgatttg
      661 ttctccactt gtccgaccga tcaattcttc attgatcagt tggcctagtt ccccatgata
      721 gctgtctctt tgaatatacc catcttgcag cggtgaaatg aagtccccag cttcttttag
      781 aacaccgtcc atggtatcaa aaataacaac atctgcggct ttgattattt ctcgtggaat
      841 ttcacacatt tccggtgtgt aagcaccgac tccattgatg tgcgcacctt ttttgaccca
      901 ctcagcagag aatgtcgcac gttttgaagt ggtcacactt gtaatgatgt ctgctccttc
      961 aacgcattct tgactggttt ttgttgggcg catcgttaca gaaaattgtt gcatcatttt
     1021 ttcagcaaat tggctggcac gctcaaaatc aatatcaaaa atccgaactt cttctaattt
     1081 acgaacggtc aacattgctt ctaattgtga ctgtgcttgt ccgccggttc caatcagcgc
     1141 gccaatttta gcatcttctc ttgcaagaag ttctgttgct gctccttgaa cagcgcctgt
     1201 tcttaattgt gtcaaataag taccatccaa acaagcggat accatacccg tttctggatc
     1261 caatacgatc atcgttgctg gtacacttgg taagtttttc ttgatgtttt caggatacac
     1321 ggaaacgatt ttgacaccta gcgcgccttc gccaccttct acataagcag gcatatataa
     1381 gctttgtccg ttgctttttg gcacatcgat attggtgcga agaggcacac ttgcctttcc
     1441 tgctgaatac aatgacagtg cttttttgtc cgcatcgatg gcttctctca ttgaaaaact
     1501 tttgataata tcttcttttt taagaaataa catttgaatc gctccttaat tagctgctgt
     1561 aacttttttt aattgactgc ccaacatcgt atatgcactg tatagtaaga ccaaaatcac
     1621 gatccatttc aggatatagg tatctaaaga tttgactagg aatacagcga ccaatacccc
     1681 caatacaccg aaggttgaag taaaaagtgt gatttttctg ctgtattcat taaatttaat
     1741 gaattgaaca ctgccgatcg gtactgagaa ggtacaagcc cccatcataa taggaaaggc
     1801 tgcaactgga ttcaagccta gcaagtagac agttaccatc gttaacgcat aagaaccaat
     1861 gccgatattg ttcaatgcac catagacaaa gagtaaaaat cctgccaaga ttaattttcc
     1921 gccatacaat tcactggctg ttccgtttga tggaatccag ttcatttgtc ctgcaaaaat
     1981 caacaatgca gcaatgacca atcctatgcc gacaaacagt ttgatcgttt tctctggtaa
     2041 cttcacgaca aatcttggtc ctaaatatgc accgataatt tggcagataa tacaaacagc
     2101 tagtgtcttg atccctacgt tgatggcagt gatgtaagac aatgccatga cggctaccgg
     2161 tactacacat tgggtattca acgttccggg tagttttttc atgctgaccc atttcaactt
     2221 tggataaagg acggttccga tagcaaagtc ggaaacgcca aatgttgaaa gaaagaagat
     2281 gataaatgac gtgaagggca acagacgcat atcccctggt tcttctttga aattttgttt
     2341 gtttttgaaa aggtctctta gaaagtaaat aataaaatat agattgattg cgacaattag
     2401 tgtcagcaaa atattccgaa tcataaaaaa ttcctcctac tagtaaatct ttctgattcc
     2461 ctcaaagccc tcaccatatt ttgctttaag ttcttcagga gattctgcaa tcacttttag
     2521 tgtatatgca tcatgtttga catattcttt tgctagattg accatggcgt ggttttttgt
     2581 ccaagtgaca tcggttgatt gcagttcttc gttaatggta ccaaacacga cttcttgctc
     2641 atcggcgacg atgttgatcc atcttgctcc aaagtcagca agtttgtctg tttcaaaacc
     2701 atgaatataa tacttttcta agggaagatc atattcatgg gtagaactga ataaaatcag
     2761 tacaaactta tcaactcttt tttcagcttg ctgcaatgcc tttagtagtg aatccgtgaa
     2821 attctcatgc caaacttgaa tgagcaaact ttcttttgcg tttttcacca aatgctctac
     2881 tttatccaga acatactcga taccatcaac tttccacagc atttcttctt catctttttc
     2941 tttgatcatc cctagattct tggtaagaaa agaaagatca tttttaacac ttttttctaa
     3001 tttctctaaa aactcatttg ccgagatggc atgataaagt ttaggttctg atttattaac
     3061 gacaatcaaa ttctttttta atagtttttc caaaatatta tatactttcg agcgtggcac
     3121 acctgagatt ttacttactt catatcctgt aagattacct ttttctaata gtgtggtata
     3181 cactcttgtc tccatctctg aaaaatcata ttttttcatg atttgaataa tcgtttccat
     3241 tgattaatcc tcactttatt tttagtagct actacggtaa caactataaa ttctttttga
     3301 ttatctgtca agagttagtt caataacaca catataataa ttagcttaaa aacaatcttt
     3361 ttattaaaaa gaaacattat aatatgaatg tttgtgaaaa aataatacaa cttagtcatt
     3421 ctttacaacg atttatagaa aaacaacctc tttaaatata aaaggtacgg gttactgatt
     3481 acttgtaaat ctttacgttc cagttttatt ctttctaaaa aatatactca cttcttttct
     3541 tagacttctt tttttgattc tcctctttat ggtcttgtcc ttttttgcct tcaaaatatt
     3601 taaataaacc cctttcaaaa gcatttctag gttttggaca ataaggaatg acttttttct
     3661 tcatataaat acctcattta actatttgat atcatcacat tatcaaaaaa aataggtttt
     3721 ttattaaaac tatcttgacc tttcgggaga tttcactgtg atttattttt attcccatac
     3781 ttttttcgtt ggtcactttc gtatacctaa tctaagcgat catcggcgac ggtgctttta
     3841 caacgaatgg caggacaaaa caaggggcgg aaaaactttt ttgcctattt cataaaaaac
     3901 tttttcctac agcaatccct tgttttgtcc taccacacgt tgtgaaccca aagcacgccg
     3961 acgaacgctt agctatacga aaatgacctc caaaaacaaa aaagtgaggt gaatagaaac
     4021 aaaaagaaat tgaaatctcc caaaatgtcg tccgcctcgg agacaacttg ctgctgaaaa
     4081 tggttggtta attcatttaa gtattaaata agataaatca tcaaattaat cggaaaaata
     4141 gcatgattgg ccttatcaaa aataaactgt aaaaacttat atttctatga gtggtggaac
     4201 aatgctaata ccaaattaat ttatcgatta cccacctgca caaaccaaag atagcattat
     4261 taggaaacga atcaatcagc gaatccagca ttataatgag gatactaaaa ataaagtttt
     4321 cataattata aatccgcctt cctacgaaag gcaccaatga ggtgatgaaa accttagagc
     4381 gctttctttc tttttttatt ccgtgttacc ctttccttgc aggtccctgg tacactacag
     4441 aacccgagga ggtgagtggc ggggctgtat agcggcaacc ccgcataatt atatggtgtc
     4501 ggtcatccgt taaggcatca atgaatggcg caaacccgta gcccgtaaac ttatctcttc
     4561 cgaagttgac tcgatttcgc cggatgacca gtccctacca aacctgtact atttttttac
     4621 aggaggttgc tatgttcaaa atctttcgta aaaattgttg tggcttggat gtccacaaaa
     4681 cgtggatcta tgcgtgtatc ggaatcacag atgcgaatgg tcgtacagtg tataagcaag
     4741 ctcgcttctc ttcctttaca aaaggtctca atgaattagc tgaatggctt gctaaataca
     4801 actgtaagga tgtgtgtttg gaatcttccg gtaaattttg gattcctgtt tttaatattc
     4861 ttgaaaaaac ttgttttgtc acactggctc atccgaagta caccaaaccc cagaaaggaa
     4921 ataaaacaga tcgcaaagat gcaaaaatgg atttgtgatc tctttatgtg cgacatgatc
     4981 aaacccagtt ttattcctgg tcttgaaatc cgccagcttc gtgatctaat gcgttatcgg
     5041 acgaaactga ccaacatgaa aacaagtgaa aagaatcgtg ctttaaactg cttaaccgtt
     5101 tctaatctga aactagatga tgtttttagt gatgtgttcg gaaaatcatc cacttctatc
     5161 atccaatact tgttagaaca tcccggtgaa tcatttgatg ttcgaccatt tatccatgcc
     5221 cgttgtaaaa ctcccgttga agaaatccaa gcggcagttg agggggcgat ttctgtacct
     5281 caagcgatta agcttcgcca atgcctcaac catattaacg agattgagaa gcatcgagaa
     5341 gagatcaatc tagagattca agctcttgca gaacccttct cccctgtttt ggaactactt
     5401 cgtaccatac cgggcttaga cactcagcca ataacagcga ttgcgattct ttcagaaata
     5461 ggaccggata tgtccgtgtt tccaacttcg aaacacttta tttcttgggc tggatgctgt
     5521 ccaagaaacg atcgcagtgc ccgacgaaca aaatcaacac gtatctctcg tgcagggcag
     5581 tcgttgaaac cgctacttgt acagattgcc aatgctcttc tcagatccaa agaacatcca
     5641 gaatttaaaa atcgctatcg tagaatcaaa gcgaatcgtg gacacaagaa agctatcatt
     5701 gctatttgta agatgctcct gaccgctatc tggaatgtct tatcaaaggt ggaaccctat
     5761 tctgctaaag gatatctgga gccaaaacct gcgaaagaag agaaagttct gacgcaatcc
     5821 caagctctgg accttttaag aaaacgcgga tataccatta tagatagtgc ttaaaccaaa
     5881 gttacgttga ttcttcctaa atagactcgt tgtcttccat ttcaaaaatt ttgaaaacgg
     5941 taggcttatt tagtgtaccg ttcttcaggt atcttcaaat agatttattt tcaaacttat
     6001 ttcctttctt cttttactct cctatagctt agcatttaag tgggcactcg tgtcaccttg
     6061 ctagatagct atgaatgccg taataagcct cctagtatat aggcagactg ccaattataa
     6121 ctgattcaat ccacattatg ataaaatcca ccttttcgtt tcatatgtgt tgaaatatca
     6181 catatgtcaa aagtgcacga gtcttttcat tcagtgcttt gtaaatactc aaaattattc
     6241 cttttcactt taaaaaaaag ataattagta caaaatcaga aatgaggaaa gtattaggat
     6301 ggactagaaa ggagttgttg aatttgttgc aacagattgg tcatttatca attaaaaatt
     6361 aggtgaagtt ttattcatca ctgcagctgc tgtttcccag agaataaaac gtctagaaga
     6421 aactggtcag ttactgtatt atcaagcagc aattgactac gaacaagctt gattactaac
     6481 caaagcgttt atccacctgt tgattaaatc aaatcaaaaa tcaggttttt atacgttcat
     6541 aaaagcaatc tccagtgtac tcgaatgtga ctgtatcata ggtccttatt cgatgttaat
     6601 caaaatgggg tttccttcta ccgaatcatt ggacagtttt atcaatgatt tatcaaagtt
     6661 tggacgaacc aacacccaaa tcgttttctc gactcttgtt tccttaatgg tttatcagtt
     6721 ctggaatgtt tatcatgcgc ttttattaaa atagaaaaga gcttttttca tgcgacaaag
     6781 cagtgatcat ttattggcac atgcaatctt tgtggatcca ttttttgaaa atacgatatt
     6841 tagttttgac ccaaaaatct ttaaatacgt atttgataat ttatcttaac aaccagataa
     6901 ttttattcag caccgtatta tctatattga attctcggaa tcaagataaa tttttttccg
     6961 tttttgtttc ttttttaatc ttcttcttgt tattaatagt gattaggatg atattcctat
     7021 attgatcttt gataattaga tataattttt gaataacgtt ccctgctatt cgagctagaa
     7081 atacaagtac gccatgacct agttagcgac aactacttag agatttcttt tgttctggga
     7141 caacaaaatg ccatgacaat agcagtaaat aatgatactt ccgtaaggct cgccgtaaac
     7201 tggggagagg tgaaattcct atgtgcttac ccaaagcggt tcaaaaattt taaactatta
     7261 ttttaggaga tgattttata aaatcgaaag cctacttgaa taaaaaacaa gcctgtgaat
     7321 ttctaggaat tgataataat actttagata agtggattcg tgtatataat tttccagtaa
     7381 taaaaattga tggcgtagtt cgctttgacg tagaggatat caaagatttc atgaatacat
     7441 tcaaaaaaaa ttgaaatttt cttctcgtca catatactat aaatagcgaa atgtactgcc
     7501 ttacttttta aaggagtgag gaagtttgcc tacaaagctt tcaaatggga aatataaaac
     7561 taatctgagg tatccaaaaa aattcagaga aatcactgga attgcatcag agaagtatca
     7621 aaaagtattt ccaactaggc aattagctat taaggccgaa agggaaatga aaaagaagat
     7681 tgaaacagtt ttaagagagg agaatgcaaa ctcactagaa ttgaaaggaa aaataaaatt
     7741 taaagatttt tatgaatcaa aatggcttcc tagatatgaa ctaggtcaaa ctactaggtc
     7801 aaacagggct ccaagtaatg taacaattag taatactaag gatatattcc gattgcacat
     7861 ccttccaatg tttggtgaat atgcaatgaa ttatctgaat tcaaatactg agataatatc
     7921 agatgaatta acaaagaaat cgaaagaata cgcaaatata aaaattatca aaggctatgt
     7981 tcgctctatg tttgatattg ccgaaatact atgttatatc gaattcaacc gaactaccaa
     8041 aattattcaa tgtattaccg cgcctaagaa aatggcttta gaagaaaaaa ggataaggga
     8101 agggaatcaa gcattatcat cagaagagct gactgattgg atagaagcag taaacaatga
     8161 cttaaataat cacttgctta cacttcacga ttacacactt ttcatgctta ccttatatct
     8221 aggtgataga aaaagtgaga cttatgctct gcaatggaaa tatattgatt ttaataaaaa
     8281 tacggttcgt ctcaaatatg ctttagataa atatcaaaga aagacacata caaaaggttg
     8341 gaaagacacc gttattcagg caccagaagt tgtgatgaca ttattaagag aatggaaatc
     8401 agctcaggct gaacaattgt tgaaactaaa aattatacaa acacctgacc agtacctctt
     8461 tacctattcc aaaccttctg gagaagtaaa ttgtcctgtt cacgctgact acttaaacta
     8521 tcgaatcaat gcaataaaaa aaaggcatcc tgaattggct caattatctc cacacaaact
     8581 tcgtcatacc tatgcaacta tagctaggga aggtggagca aatatgaatc aaatctctaa
     8641 tgctttaacg cactcggata tttctactac aaaaatatac gtgaacacac ctgacgtagt
     8701 tgataaatct gtttttgaag catttcaaaa aggattgaat aagtgtgatt aacatgtgtt
     8761 ctcaaatgtg ttcttattat aaaaaaagac actttccaaa taattgaaaa gtgtcctgaa
     8821 atattgatat aaaaagaata ttaacgtttt gagaattgtg aagctttacg agctttttt
//
LOCUS       DADGKS010000094         8726 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.098, whole genome shotgun sequence.
ACCESSION   DADGKS010000094 DADGKS010000000
VERSION     DADGKS010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8726
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.098"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            86..1093
                     /locus_tag="JXV47_002525"
     CDS             86..1093
                     /locus_tag="JXV47_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAX1488534.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            1105..2109
                     /gene="neuB"
                     /locus_tag="JXV47_002526"
     CDS             1105..2109
                     /gene="neuB"
                     /locus_tag="JXV47_002526"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HAX1488535.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            2106..3254
                     /gene="neuC"
                     /locus_tag="JXV47_002527"
     CDS             2106..3254
                     /gene="neuC"
                     /locus_tag="JXV47_002527"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HAX1488536.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            3227..3904
                     /locus_tag="JXV47_002528"
     CDS             3227..3904
                     /locus_tag="JXV47_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAX1488537.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            3894..5036
                     /locus_tag="JXV47_002529"
     CDS             3894..5036
                     /locus_tag="JXV47_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HAX1488538.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            5049..6026
                     /locus_tag="JXV47_002530"
     CDS             5049..6026
                     /locus_tag="JXV47_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAX1488539.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            6026..6934
                     /locus_tag="JXV47_002531"
     CDS             6026..6934
                     /locus_tag="JXV47_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HAX1488540.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            6935..7687
                     /locus_tag="JXV47_002532"
     CDS             6935..7687
                     /locus_tag="JXV47_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HAX1488541.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            7692..8639
                     /locus_tag="JXV47_002533"
     CDS             7692..8639
                     /locus_tag="JXV47_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAX1488542.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT         3212 a         1100 c         1672 g         2742 t
ORIGIN      
        1 attattgata attagtttag ttatatattt tttaaagatt aagaatcgaa ttatagatga
       61 ctataattca taggaggaga tataagtgtt taaaggaaaa acaatattag taactggcgg
      121 aactggttcc attggaagtg aaattgttcg tcagctttta aaatatgaac caaaagctat
      181 cagaatttat agtagaggtg aagaaaaaca attttatatg caacaagagc tctcaaatca
      241 cactaatttg agatttttaa ttggtgatat cagagactct caaaggattg attatgcatg
      301 tcgtgatgtg gatattattt ttcatgctgc cgcaatgaaa cacgttccag caagtgaata
      361 taatcctatg gaagctgtaa aaacaaatgt gatgggaact caaaatgtaa tagatgcagc
      421 gatcaaaaat aatgtaaaac attttgtagg tatcagtaca gataaagtag tgagtcctac
      481 taacaccatg ggtgcgacaa agttattgag tgaaaaatta ataatagctg ccaatcagta
      541 taaaggaaaa acagaaacaa tattttcttg tgtaaggttt ggaaatgtca tggggtcaag
      601 tggatctgtt attcctcttt ttagtaaaca aataaaaaac aataaagata ttactttgac
      661 agatgttgat atgacacgat ttatgatgtc aataccggat gctgcaagat tagttctgtc
      721 tgctgctatg aattcaaaat ttggagaaac atatgtctta aaaatgccgg caatcaatat
      781 tttaacttta gctcaatcat taataaaaat atataatgat acacatgatg aaaaatatag
      841 aggtgaaata aaagttgtag gtatcaggcc aggagaaaaa ttatatgaag agctaatgac
      901 tacagacgaa attgaacgct catatgaaaa tgataaaatg tatatcattc caccacacta
      961 tcatgctact gacgaactgt acaaagatta tgaaaaaatt aaaatcactg catactcttc
     1021 agatgcaaca gaattaatga gtggacagga atttattaga atcgcaaaag agaataatgt
     1081 cgtgacttgg taaggagttt tatgatgaaa tcagaagtat atgtaattgc agaaattggt
     1141 gtaaaccata atggaagtct agatttagct ttagaaagta ttgataaagc taaagaatgt
     1201 ggagctaacg cggttaaatt tcaaacattt aaaacgaata agctagtttc caaaaaggct
     1261 ccaatggcaa aatatcagaa ggataatctt aaagaggaca gttctcaatt tgaaatgcta
     1321 aaaaaattag aattatctca atctgatttt attagaataa aagattattg tatacaaaat
     1381 aaaattgatt ttttgtctac tccttttgat gaagaaagtg cagactttct aaaacaaatt
     1441 ggtgtacaag gatttaaaat tggctcagga gatttaacaa atttaccttt tcttagaaaa
     1501 atagatatgt atgggttgcc agttttatta tctacaggta tggctgatat tcatgaggtc
     1561 agtgaggctg tagattgttt catagatagt ccagttacta ttttacattg tacttcaaat
     1621 tatccggcta gttctgaaga tattaattta ttggcgatta acacattaaa agaaatgttc
     1681 gggatacccg ttgggtactc cgatcattca ttgggatatg atgttggtat ttgtgctgtt
     1741 gcgatgggtg ctaaggtaat tgagaaacat tttaccttgg ataaggaact acctggtcca
     1801 gatcataaag cttctttaga tcctcaggaa tttgcagatt ttgtaaagca tattagaaac
     1861 actgaaatat ttttaggtga tggtgttaag cgagcaatgc cttctgaact tagtacaaaa
     1921 gaagtatcaa gaaaaagcct agtggtcact gagaatttaa atgtgggaga tattcttaca
     1981 gagaaatctc ttacaataaa acgtcctgga aatggaatag ctcctaagtt tttatatcaa
     2041 tatattggca aaaaagttaa aagaccaata agtgcagata gtgttctgct tgaggaagat
     2101 gttgaatgaa aaaaatactt atagtaagtg gaacacgagc tgattatgga atatataaac
     2161 ctgttgctga gaatttacta caagataatt gggatgtatc atttgttgtt tctggaatgc
     2221 atttatccca taaatatgga tttactaaag aattgatctt agctgacgga tttagaatta
     2281 gtggagaagt tcaaagtttg tttttagaga acaataaggg aaacatggct cggtctgtgg
     2341 cattagagat aaatggtttc acaaatatat ttgaacaaac tagccctgat tttgtattat
     2401 tactagggga tagaggagaa atgttggcag ctgcgatagc ttgtttgtat cttggaatca
     2461 aaacagcaca tattcacgga ggcgaagtgt ctggtactgt agatgaatca ataagacatg
     2521 ccataacgaa aatagcatct gttcattttg ctgctacgga aaaaagcaaa gagcgtttaa
     2581 taaaaatggg ggaagattct tggagagttt ttcccgtcgg agctcctaga atagatacta
     2641 ttttaaataa tagattacct agttttagag atataaaaga aaaatatcat ctaaaatttg
     2701 aaaagaaaaa atacgttttg caagtatttc atccagttgt aaccgaacta gaaaatatag
     2761 aaaaacaaat tttagctttg atcaattcaa tggaacaaca atctcaacca attatttgca
     2821 ttttacctaa tagtgatgct ggtagcgaaa ttatcagaaa aatgtaccag aaatatttaa
     2881 aaacggatat tatttatatt acgaatttag agccggagga atacctgact atattaaaag
     2941 agtgcaaatt tatgatcgga aattcttctt ctgggataat tgaagctgca tcattcaaaa
     3001 taccagtaat aaatttagga accagacaaa atggacgaga acaatctaaa aatattataa
     3061 atgcaaatct aaatgaaaat gaaattgaaa ctgctttgaa taaaatacaa gatcctcagt
     3121 ttataaaaag cttgaaaaat gttaagaaca tctacggtga cggcaacagt tctagaagaa
     3181 taacaaaaac attgaatcaa atattgaatg atggggaaga tattaagtgg attcaaaaac
     3241 aaatagctta ttaaaatata ctagtgatcc atacattatt attggggctg gcggacacgc
     3301 aaaagtcatt attgaaacct taagattaga aaataagtta atatatggat tttttgatga
     3361 taagcaaaat aaaatgcaag atctgaaata tcttgggaaa ataaacgaat tgaatagctg
     3421 ggcggatagc aaaaaaaaaa tctataaatt tattgtagct attggtgact gtgtagtaag
     3481 aaaaaagatt ataaaaaaat tgaatatgcc aagtgagcaa tatggaatag ctgttcatcc
     3541 aagtgctata gtggcaaaag aaatttcaat tggttatgga actgttattt ttgcgaatgc
     3601 tgtaattaac ccagatgctg taattggaga gcatgctata ataaacacag gtagcattgt
     3661 tgagcatgat tgtagaatta ataactatgt tcatttatct ccaggtgtat gcttagcggg
     3721 tggagtacat gtaggtgtag gaactcaaat aggaattggt tctcaatgta tccagatgaa
     3781 gaaaattgga tcttggtgta tgataggcgc agggagcact attgttaagg atattccctc
     3841 acattcctta gcttatggca atccagctaa aattaagaaa gaaggaatta attttgaatt
     3901 ctagaatttt attatcaagt cctcatatgg gaggaacaga agaaaaatat gttgctaagg
     3961 cttttaaaga taattggata gcgccattag gtgaaaatgt ggataaattt gaagaaagta
     4021 ttacaaaata tactggttct aagggcggag cttctgcgtt aagttcaggt acagctgcca
     4081 tacatcttgc cttaagactg cttaatgttg gaaaaaacga tattgtcttt gctccttcat
     4141 ttacttttat agctacagta aatcctattt tatatcaagg ggctgtacca gtgttcattg
     4201 actcagaacc taatacatgg aatatgagcc ctgttgcact agagagcgca ttagaagaag
     4261 ctgaaagaaa caaccaatta cctaaggcaa tcatcgtagt gaatttatat ggtcaaatgg
     4321 ctgattatga acgaatttta gctattgcaa accaatttaa tgttccagtg atagaagatg
     4381 cagcggaatc gttaggttct acttataagg gaatttcgtc aggcttattt gggacaattg
     4441 ggatctattc atttaacggt aataagatca tcacaacctc aggtggagga gctctagtgt
     4501 ctagtgataa aaaatatgtt gagcattcaa gatttttagc aacacaagca agagatcaag
     4561 caccgtatta tcaacatagc gaaataggtt ataattaccg tctaagcaat atttctgccg
     4621 gtatcggacg tggacaaatg gaagtattga atgatagagt agctaaacga agagaaattt
     4681 tcaatcgata taaggaagct ttttctggaa ttgatagaat tgaaatgatg ccagaagtgg
     4741 atggcatggt gccaaatcgt tggttgtcta ctttaacgat caatgattat aattctattg
     4801 atcaagtagt taacgtaata aataaactaa atgaaaaaaa cattgaaaca agagctttgt
     4861 ggaaaccact acatttgcaa ccagtatttc aaggggtaaa aatgtattac catgataata
     4921 atcttagtgt gtcagaaaag ttatttaata gcggcttatg cttaccttct ggaagtaata
     4981 tgacagatag tgaacaagaa tttgttattg atgagtttaa aaaaatattc aagtaggtgt
     5041 gatattttat gaacatagga attattggtt taggttccat ggggaaaaga agacttagac
     5101 tcattcaaga acactttaat gatattttac tatgtggtgt tgatactaat gaggcgagac
     5161 gaaaggaagt tgaaaaggaa tttggaatac caacttataa tagtctaaca gaggcaaaaa
     5221 atttgtttga aataaattca gtttttgttt gtacatcccc tataacccat gaatttatta
     5281 taaaagaggc tttaaattta gattgtaata tctttacgga aatcaattta ttaaatgaat
     5341 attatgatga aataatcgaa gtagctaaaa agaaagatag attactttat ctatcttcta
     5401 catttttgaa gagaaaagaa attcaatata ttaagtctaa agtgacgcat aataaaaaaa
     5461 tttcttatca ataccatgta ggacagtatt tacccgactg gcatccttgg gaagattatc
     5521 gcaatttttt tgtttcaaac aaaaaaacta atgggtgtag agaaatattc gctattgaat
     5581 taccttggat tatagataca tttgggaaag ttaaatcgtt tactgtaatg acccagaaat
     5641 tatccaatct tgatattgat tattcggaca gtttcactct tattattgag catgaaactg
     5701 gtatagttgg aactttaagt gtagatgttg tttcaagagt agctaaaaga aatttaacta
     5761 taattggtga aaagatttta atagaatggg aaggtaaccc ggattctcta ttttcatgga
     5821 atgaagaaac ttctagtatg acagatattc aattgtacga tgaggttatg catgataata
     5881 attattcaca tactattatt gaagatgcat atttagagga gattaaagaa tttttcacgc
     5941 ttttggaaaa gaaaatggaa ccccaatata cttttgaaaa agataagtat attattaact
     6001 taattaacga cattgaggta aattaatgat gaaagtaatt ttttttgggt tagggtcaat
     6061 tggaaagaga catctaaaaa atctaataag ctatggaaaa aagaattcta ttaattttga
     6121 tataacagct tatagtagca gtggaaaaaa agagtttgaa gaaataacgt atattcaaaa
     6181 tagagacgat ttggatacac attatgatat agcttttatt acaaatccga cttttaagca
     6241 tctggaaaca ctaaatgtaa ttgttgaaaa agttgattac atatttttag aaaaacctgc
     6301 tttttctgag agtattgatc ttactcaata taattatgat tacaaaaata tttatgttgc
     6361 tgctccactg aggtataaaa atatcatgga agttgttcgt aatagtattc aaagtaaaaa
     6421 agtatattct gtaagagcta tttgttctac ttatcttcct gattggagaa aaggtactga
     6481 ttatagaaat aattattctg cctttaaatc tatgggggga ggagtagaat tagactgtat
     6541 acatgaattg gattatatta taaacctatt tggtttccct aaatcagtaa aaaaacagtt
     6601 tggtaaatat tcgaatcttg aaattaacag taatgattta gcaacatata tattgagata
     6661 cgatgataaa attatagaaa ttcatttaga ttattttgga agagttccta caagaaaatt
     6721 tcaattgttt actttagatg aatgtatcaa tgttgactta ttaaataata aaataagttt
     6781 tgaagaaaac attgttaaag aaatgcctga atctgctaat gatatgtatg agaaggagtt
     6841 gaaatatttc tttgaaaacg tagtaacagg caaagaaaac tggaatgatt tatatcatgc
     6901 aaacgaagta ttgaaaatag ctgaggagaa ataaatggaa attttattta ctatttgtgg
     6961 tagagctggg tctaaggggt ttaaaaataa aaatttgaaa tatttggcag gaaagcccct
     7021 agtccatttc gctttagcaa tgatagatat ctatcaacaa aaacatcctg aacataattg
     7081 cacgacttgt ttgaatacgg acagtaatga gttagtagaa ttgacgacta agttaaatcc
     7141 gtctgtgaaa attgtagaac gtaaacctga attagctaca gatactgtag ggaaaattga
     7201 agtgatacgt gattcattct tacaactaga aagagaagat aatatatttg atttaattat
     7261 agatttagat ttgacttcac ctttacgtga agtttctaat cttgaagaat taatagatga
     7321 acatctaaaa aatttagata aagacgtcta cttttcagtt gtttctgcaa gacgtaatcc
     7381 ctattttaat atggtaaaaa gaattgaaaa tgaagttact atagttaata aatcaagata
     7441 cacatctagg caacagacac ctgaagtttt tgaaatgaat gcctcaatgt attcttttaa
     7501 acctgaattt ctaaaaaaaa gtaattatat ttttgatggg caatgtggga taataaaaat
     7561 gagagattat ctaattttag atattgatag tgaagaagat tttaaatggt tagaattttt
     7621 gtttcctaaa tttttagaag attcttcgga gcttcaagat atctataatt atttatatcg
     7681 gaggtaaaag gatgagctgt tatcttatca ccggtggggc tggcttcatt ggttctacct
     7741 tagccaatca tttaggagaa gaacatgtgg taatcgtcgt cgatgactta tcaatgggaa
     7801 aagtagaaaa tcttgatatg acgaaaaata tcacttttat tgagggagat gtcgctgaga
     7861 aatccttgat ggaagagatc atgaaagcta ataaatttga ttatatcttt catttagcag
     7921 cagttgctag tgtggcagat tcagttgccc gaccagtaga aacacatcgt gtgaattttg
     7981 aaagtgtatt aatgatttta gaattgatcc gcaagtatca acctgattta aaacggatcg
     8041 tgtttagttc ttcagcggct gtttatgggg atgaaccgac tttaccaaaa aaagaagagt
     8101 ccgtgattcg cccattgacg ccttatgcgg ttgataaatt cgctgcagaa caatatgtgc
     8161 tagattattg tcatttatat gatgtacccg gtagcgcagt tcgttttttc aatgtctatg
     8221 gtccaaatca aaatccgaat tctccataca gtggtgtgat ttctattctc gtagatcgct
     8281 ataagaaaca aatcgtagga gaagcaactt catttacatt atttggtgat ggaagccagt
     8341 ctagagactt tgtttatata gatgatgtaa tccaagcatt acttttagtt gcgaatgagg
     8401 aagctgcact ggggaaacaa ttcaatgttg gaacgggtaa agcaaccaca cttttggaat
     8461 tgattcatgc aatcaatgaa attctcggtg tagaattgac acttgaatac aaagaagagc
     8521 gttcgggtga tatccatgac tctctagcag atattactaa gatccagtca attggctatc
     8581 aaccgaaata tggtatttta agtggaatga ctaattattt gaaaactgaa atcaattaaa
     8641 acatactaag ataagattag agggtaaatt caggctcttt gtcaataagg actgatgagt
     8701 tttgtaaaat caaatctggg atagaa
//
LOCUS       DADGKS010000095         8675 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.099, whole genome shotgun sequence.
ACCESSION   DADGKS010000095 DADGKS010000000
VERSION     DADGKS010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8675
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.099"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..1101
                     /locus_tag="JXV47_002534"
     CDS             <1..1101
                     /locus_tag="JXV47_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAX1488543.1"
                     /translation="KKETIVRFEQYNHMPLVTRLKKQRYTCKNCRTHWTAQSYFVRLS
                     HSIADHVRYKIASLLTEKVSLSFIAKSCQVSLTTVTRTLKEFKSYLPKPSKKILPRVL
                     MVDEFRSHASIEDKMSFICADGETGNLIAVLPTRKLPRLTSYFLGCTNPEEVEFLVTD
                     MNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQALNELRIREMNELRKAGQKSQAEKLKK
                     NWRFLLKNRASINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSAPLKEAYPFFHELV
                     EAFRDKDPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITSAMIYPYSNGKIEAKNT
                     HIKTMKRVSYGFKSFENMRIRIFLINQLINVR"
     gene            complement(1280..1615)
                     /locus_tag="JXV47_002535"
     CDS             complement(1280..1615)
                     /locus_tag="JXV47_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAX1488544.1"
                     /translation="MKMNTNDIATVYVAFTAAEGGKRRPVYILKNGLDTISFLSITSK
                     YHTKSDKIKLKYVEIRDWKQAGLKKESWIDVGTLNELPKNNKKVKWKKIGELSPSDLQ
                     RLEERMEEL"
     gene            complement(1599..1871)
                     /locus_tag="JXV47_002536"
     CDS             complement(1599..1871)
                     /locus_tag="JXV47_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HAX1488545.1"
                     /translation="MEKMAKLQISMDEKLKNEAESIIDELGMSPKTAVTVFYKQIVEQ
                     GKIPFSIELSEKSKRIHNIQRLAEKLPVQKLDTDEKIEEWFNEDEY"
     gene            complement(2322..3125)
                     /locus_tag="JXV47_002537"
     CDS             complement(2322..3125)
                     /locus_tag="JXV47_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAX1488546.1"
                     /translation="MRFLHLSDIHFRENYQTNLFTAELFPTIKNPQLALEKLLQELSL
                     TVYDFILLTGDLVHEGGISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVES
                     NETGEYIHCTNQNGLRIISLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLVHH
                     PLSWEDPSIVTEVPEGFAELIAESDILGIFVGHIHQGSSAEFAGKKQFMAESLSFGVD
                     EYPDYSLFTNRTGFTSGSLIDGKIFTYQHYLTPHQIEIGRMKKPITGNH"
     gene            complement(3103..4227)
                     /locus_tag="JXV47_002538"
     CDS             complement(3103..4227)
                     /locus_tag="JXV47_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1488547.1"
                     /translation="MGETLELRNIGKKYGEHTILKEIDLAVAAGERIVLLGPSGSGKS
                     TLLRMIAGLEKITSGELFLGTQLANKLPCGEREIAMVFQNYALYPHMTVKENIIFALR
                     ANKIKTADIQHRLEEALKMLGLTPYQDRLPKDLSGGQRQRVALARAVVKRSNYFLLDE
                     PLSNLDVRLRLDARKELVKIHQRYKQTFVYVTHDQIEAMTLADRIVLLNEGRIQMIDT
                     PKNVYTKPKNTFTANFIGSPGMNIMPVTYDQGTLKVASQFLTLNPAWQKQLLQVSGSL
                     YLGIRPEHVTFSKETSDLHGQVKYRELLGQSYAYTVKVDGIEMIVLNEKPTWQIGDAV
                     NLRIEPERMHFFDYQTQENLGYPDYFIEERGNSHALFASL"
     gene            complement(4243..5058)
                     /locus_tag="JXV47_002539"
     CDS             complement(4243..5058)
                     /locus_tag="JXV47_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAX1488548.1"
                     /translation="MKIKRWLPHLLFMFIIIIIIYPLLFIMANSFKPLKDAYQTITSL
                     IPQPFTLENFCYLFENLPIIKITRNTFFIATIITVVKLGVAFFAAYSFTYCRIKGKKI
                     WYFIIIGTMFIPFTVAMIPNYLLIAKLNLIDTTWGVIIPQFADAMGIFLLTQTMREIP
                     VSLLDVAALDNIKQTTVMSKIVFPLTRHAITSTGIWFFITSWNEYVWPVLILRTVDNY
                     TLPLAMQTYISSEGGTNFTVAMAISLITMFVPLVLYAIFQKYIIGTFVSAGIK"
     gene            complement(5048..5929)
                     /locus_tag="JXV47_002540"
     CDS             complement(5048..5929)
                     /locus_tag="JXV47_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1488549.1"
                     /translation="MSEMKRYVGYLYLAPAIILLGVFVFYPLIYTIYLSFFDWNMVAP
                     TKEFVGFANYVKVLTDPVFHKVLKNTLSYTVLFVLLSCVFPYITSFLLGIVIEKGQNL
                     YKPLFFIPAVISLVVAGMVFTWILNPVSGPIAVLLGNFGLRLPMWMNLQGWVIAVIAG
                     ITAWKVFGYNFIVIFAAIVGIDQEMIEAAKLDRVPIWRIFFTIVLPMSSSTGLYLLVM
                     TIVQGLQYVFTPIKIITRGGPNNGSANVIYYAYQKAFEMYKVGESSAISVLTLLIFAV
                     FLGVIFKFVEKGVYYEN"
     gene            complement(6005..7294)
                     /locus_tag="JXV47_002541"
     CDS             complement(6005..7294)
                     /locus_tag="JXV47_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002581297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAX1488550.1"
                     /translation="MLKKNLVIGVVSVLSVISLAACGSGNTKTTKKSEGRVTIEYWHV
                     NADTLGGKTVNELVDKYNQSQDKVKVVAKYNPDMYKGLMQNLQASVASKEIPDVVQVG
                     WAFKDYFAENFKYTNPQSLVEEVDPDNADYFKDHFLDNIMALSEKDGKQVGIPYSISN
                     PVLYLNQDILKAAGLDENGPKTWEEVQTFSKIIKEKTGKYGVYIQEPADNWAQQAILE
                     SNGASVIKDGKATFASKDGIAAYELYQRMVKDQTALHTTWEQGVQSFIDGNVAMVYTT
                     IAQRDNIQKNSTFTAKAVESPSWEGKKVKLPAGGAMLAVTSQTDKKKEATWDFLKYLY
                     SVESLAKWTEGTGYLPPRKDVADAQNGLKAFLAENQMMIPAIDQMDKMVSWSSFPGDA
                     GLEAEQKLLDMRDKILSGNSVNETMKATQKEINELLK"
     gene            complement(7522..8166)
                     /locus_tag="JXV47_002542"
                     /pseudo
     CDS             complement(7522..8166)
                     /locus_tag="JXV47_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
BASE COUNT         2691 a         1850 c         1371 g         2763 t
ORIGIN      
        1 aagaaggaaa cgattgtccg ttttgaacaa tacaatcata tgcctttggt tacgcgccta
       61 aaaaagcaac gctatacctg taaaaactgt cgtacccatt ggacggctca aagttatttt
      121 gtccgactca gccattcaat cgcagatcat gttcgatata aaattgcttc tttactgact
      181 gaaaaagtat ctttgtcttt tattgcgaaa agttgtcagg tatctttgac taccgttact
      241 cgtacattga aagagtttaa aagctattta ccaaagcctt ctaagaagat tctccccaga
      301 gtattgatgg ttgatgaatt tcgttcgcac gcttccatag aagataaaat gagctttatt
      361 tgcgcagatg gtgaaacagg aaacttaatt gctgtcttgc ctacgcgtaa attacctcga
      421 ttaacaagct atttcttagg ctgcaccaat ccagaagaag tagaattctt agtcacagac
      481 atgaacgccg cttacttcca gcttaccaaa cgtgttctgc caaatgcgaa agtagtgatt
      541 gatcggtttc atattgtcaa acacatgaat caggcactca atgagttgcg tatccgtgaa
      601 atgaatgagc ttcgtaaagc aggacagaaa agtcaggcag aaaaactgaa aaagaactgg
      661 cgctttctgc taaaaaatcg tgcaagcatc aaccattatg agtacaaaac atggaaaagt
      721 ttccgagcac caaaataccc atttctcact gaagcaatga tgattgatcg attgcttgag
      781 ttttctgcgc ctctaaagga ggcgtatccc ttttttcatg aattagtcga agcctttcga
      841 gacaaagacc ctgacttatt tttctcctta ttggcagaac ttcccgaaac gttagatgac
      901 ggctttcggg agaagcttca aaaccttctg acctatgaag aaggtatcac cagcgcaatg
      961 atctatcctt attccaatgg aaaaattgaa gcgaagaata cccacataaa gacaatgaaa
     1021 cgagtatcct acggatttaa atcattcgag aacatgagaa ttagaatctt tttgatcaat
     1081 caattaatca atgtaagata acaaaaaatc tgaaccagaa tgtggttcat tctgacccgg
     1141 atttgatttt gcacaactca tcagtcctta ttgacaaaga gccaaaaatc tgagccagaa
     1201 tgaggttcat tctgacccag atttgatttt gtacaaccca tcagtcctta ttgacaaaga
     1261 gcccttcttt ttagtattat tataattctt ccatgcgttc ttccagtcgc tgtaaatcgc
     1321 ttggacttaa ttccccaatt tttttccatt tgaccttttt gttgtttttg ggtaattcgt
     1381 ttagagttcc tacgtcaatc caagattctt tttttagtcc tgcctgtttc caatccctta
     1441 tttcaacgta tttcagcttt attttatcgg atttagtatg atattttgaa gtaattgaca
     1501 gaaacgaaat tgtgtccagt ccatttttta gaatatagac aggccggcgt ttaccgccct
     1561 ctgcagctgt gaaagcaacg tagacggttg ctatatcatt agtattcatc ttcattgaac
     1621 cattcttcaa ttttttcgtc agtgtctagt ttttggacag gcaatttttc cgctaatctt
     1681 tgaatattat ggattcgttt acttttttcc gacaattcaa tagaaaatgg gatttttcct
     1741 tgctcaacaa tttgcttata aaaaacggtg acggctgttt tggggctcat gcctagttca
     1801 tcaataatgc tttctgcttc atttttcaat ttttcgtcca tagaaatttg taacttagcc
     1861 attttctcca cctctttctg acaaacacat tatatcacgg aaagagttca aatggaatta
     1921 atacaactac ttttgaactc cttgaaatgc agtgtattta tctaaatata aggaaaggat
     1981 atagtgctaa atggccttga tagatagaaa agtttcaaaa tccgccacag cgataattga
     2041 agcgaacact caacgacaca cagaacagga aaagactcct aaaagaacca aattaactag
     2101 gacgtgtctg aaaactccac aaagatgtgg tatgctctgg taaaaaacga atggcacaac
     2161 cacgaagacc gatatggttc ttggaaaact ttctccaccc tttttgtaat tggagggata
     2221 gtggtttatt gatagcgatt ttccaagttc ttcaagtgga accagacatt gagcaccacg
     2281 gctaaaaagt gaatgaagtc tttattttta atcaataatt tttaatgatt accagtaatt
     2341 ggttttttca tgcgccctat ttctatttga tgtggagtta aataatgctg ataagtaaaa
     2401 atttttccgt caattaaact gccactagtg aatcctgttc tattggtaaa aagagaatag
     2461 tctgggtatt catctacacc aaatgataaa gattcagcca taaactgttt tttaccagca
     2521 aattcagcac tgctaccttg atggatatgt cctacaaaaa tacctaaaat atcactttcg
     2581 gcaatcaatt cagcaaaacc ttccggaact tcagttacaa tagatggatc ttcccacgac
     2641 aatggatgat gaaccaataa aatcgttccc ttttcagcag gtgtacccaa ccactcttgt
     2701 aattgaatca tctgtcctat cgatattttt ccttcgtgct gggtatcttg agcagaatcc
     2761 aaggaaataa ttcgtaaccc attttgattc gtacaatgga tatactctcc cgtttcattg
     2821 ctttcaacac tcattccttc aaagaaaaca ctgcgacgat catgattccc acgacaaaaa
     2881 tagtaaggtg tggttgggaa atattgatcc aacattttcc gtaagacttg ataatcagaa
     2941 atcccccctt catgtactaa atcacctgtt aatagaataa aatcgtacac tgttaacgag
     3001 agttcttgta acaatttttc caatgccaac tgtggatttt taattgttgg aaatagttca
     3061 gcagtaaaca agttagtttg atagttttct ctaaaatgga tatcagagag atgcaaaaag
     3121 cgcatggcta ttccctcttt cttcaataaa ataatcagga tatcctaaat tttcttgcgt
     3181 ctgataatca aaaaaatgca ttctttcagg ttctatgcgg agattgactg catcaccaat
     3241 ctgccaagta ggtttttcat taaggacaat catttctata ccatcgactt taacggtgta
     3301 cgcataactt tgacctaata gctcacgata cttcacttga ccgtgtaaat cgcttgtttc
     3361 ttttgaaaag gttacgtgtt ctggtcttat gcctaaatac aatgagccac taacctgaag
     3421 aagttgtttt tgccaagctg gattcaatgt taaaaattga ctggctacct ttaatgttcc
     3481 ttgatcataa gtaactggca taatattcat gcctggcgaa ccaataaaat ttgcagtaaa
     3541 agtattttta ggtttcgtat aaacattttt cggcgtatca atcatctgaa ttctaccttc
     3601 attcaataaa acaatccggt cagctaacgt catcgcttca atttgatcat gagtgacgta
     3661 gacaaaagtt tgtttataac gttgatgaat ttttaccaat tcttttcgtg catccaatcg
     3721 taaacgcaca tccaaatttg ataacggttc atctaataaa aaataattac tccgtttaac
     3781 caccgcacga gccaatgcta cacgctgccg ttgccctcct gacaaatctt taggaagtcg
     3841 atcttggtat ggcgttaaac ctaacatctt caaagcttct tccaaacggt gctgaatgtc
     3901 agctgtctta attttattcg cccttaatgc aaaaataata ttctccttta cagtcatgtg
     3961 aggatataaa gcataatttt gaaaaaccat tgcgatctct cgttctccac aaggtagctt
     4021 atttgctagt tgtgtaccta aaaaaagctc tccactcgta attttttcca aaccagcaat
     4081 cattctcagc aaagtagatt ttcctgaacc agatggtccc agtaacacaa ttcgttctcc
     4141 agcggccaca gctaaatcaa tttcttttaa aatggtatgt tctccatatt tttttccgat
     4201 atttcttaat tcaagcgttt ctcccatgat ttgtcctcca atttatttaa tacctgcaga
     4261 aacaaaagtc ccgataatat atttttgaaa aattgcatac aagactaacg gtacaaacat
     4321 tgtaattaaa ctaatcgcca ttgctacggt aaaatttgtc ccaccttcag aactaatata
     4381 ggtctgcatc gccaacggca aagtataatt atctactgtc cgtaaaatta ataccggcca
     4441 aacatactca ttccaagagg taataaaaaa ccaaataccg gtagaagtaa tcgcatgtct
     4501 agtaagagga aaaacaattt tactcatgac ggttgtttgt ttgatgttat ccaatgccgc
     4561 cacatctaga aggctcactg gaatttcccg cattgtttgc gtcaataaaa aaatgcccat
     4621 cgcatcagca aattgtggta ttatcacacc ccaagtagta tcaattaaat taagttttgc
     4681 aatcaacaaa taattaggaa tcatcgcaac agtaaaagga atgaacatcg taccaatgat
     4741 gataaagtac cagattttct tccctttgat tcggcaataa gtaaaactat atgccgcaaa
     4801 aaaagctacg cctaacttaa caaccgttat aattgtagca ataaaaaaag tatttctcgt
     4861 aattttgata attggaagat tttcgaacaa atagcaaaaa ttttccaagg taaacggctg
     4921 tggtatcaaa ctagtaatcg tctgataggc atctttcaat ggcttaaaag aattggccat
     4981 aataaacaat aatggataga taataatgat tatgatgaac ataaataaga gatgtggcaa
     5041 ccagcgttta attttcatag taaaccccct tttccacaaa tttaaatatt acccctaaga
     5101 aaacagcaaa tattaataaa gttaaaactg aaattgctga agattctccg actttataca
     5161 tttcaaaagc cttttgataa gcataataga tcacgtttgc actaccatta ttcggtccac
     5221 cacgagtgat gatcttaatc ggagtaaaca catactgcag accttgaaca atggtcatca
     5281 ccaataaata tagtcctgtc gaactactca taggcaacac aattgtaaaa aaaatgcgcc
     5341 agatgggtac acgatccaac ttagctgctt cgatcatctc ttgatcaatt cccacaattg
     5401 ctgcaaaaat gacaatgaaa ttataaccaa aaactttcca agcagtaata cctgcaatca
     5461 cagcaattac ccaaccttgt aaattcatcc acataggcag tcttaaacca aaatttccca
     5521 acaagacagc aattggtccc gataccggat ttaatatcca tgtaaaaacc atccccgcca
     5581 ctaccaaaga aatcacagct ggaataaaaa ataatggttt atacaaattc tgcccttttt
     5641 ctataactat tcctaataaa aaggatgtaa tatatgggaa cacacagctc agcaagacaa
     5701 atagaacggt ataggacaaa gtattcttca acactttatg aaagactgga tcagtcagca
     5761 cctttacata gttggcaaag ccaacaaatt ctttagtggg ggccaccata ttccagtcaa
     5821 aaaaactcaa atagatcgta taaatcaatg gataaaaaac aaacacgccc aacaaaataa
     5881 ttgctggcgc cagatacaaa taacctacat agcgcttcat ttccgacagc ctcctcatcc
     5941 ttatgtcaaa agcagacgac cttgtttttc ctttcttaca ggcgctgtcg tctgcttgct
     6001 ttgcttattt gagtaactca ttaatttcct tttgagtagc tttcatcgtt tcattgacgg
     6061 aattacctga taaaatttta tcccgcatat ccaacaattt ttgttcagct tctaatccag
     6121 catctccagg aaatgaactc caactgacca tcttatccat ctgatcaatt gctggtatca
     6181 tcatctgatt ttcagctaag aaagctttta atccattttg ggcgtctgca acatctttac
     6241 gtggtggtaa ataaccagta ccttctgtcc atttagctaa agattcaaca ctataaagat
     6301 attttaagaa atcccaagtt gcttcctttt tcttatccgt ttgtgatgta acagctaaca
     6361 ttgcgccacc agcaggtagt ttaacttttt tcccttccca acttggtgac tcaactgctt
     6421 tagcagtaaa agtactattt ttttgaatgt tgtccctttg agcaatagtg gtatagacca
     6481 tcgcgacgtt accatcaata aagctttgca caccttgttc ccacgtagtg tgtaatgccg
     6541 tctggtcttt taccatcctt tgatataatt cataagcagc gataccatct ttagaagcaa
     6601 aggtagcttt gccatctttt attacacttg ccccattact ttctaaaatt gcttgttgtg
     6661 cccaattatc agcaggttct tgaatataca cgccatactt tccagttttt tcttttatta
     6721 tcttagaaaa agtttgaact tcttcccaag tttttggacc attttcatcc aagcccgctg
     6781 cttttaatat atcttgattt aaatataaaa ccggattact aatggagtaa ggaataccca
     6841 cttgtttacc atctttttca gacagtgcca tgatattgtc taaaaaatga tctttaaaat
     6901 aatcagcatt atccggatcc acttcttcta ctaaagattg aggattagta tatttgaaat
     6961 tttctgcaaa ataatcttta aaagcccatc ccacttgtac tacgtccggt atttctttgg
     7021 aggcaacaga agcttgtaaa ttttgcatca agcctttata catatcagga ttatattttg
     7081 ctacaacctt cactttgtct tgagattgat tgtatttatc tactaattca ttcactgttt
     7141 ttccacctag ggtatccgca ttaacatgcc aatactctat cgttacacga ccctccgatt
     7201 tttttgttgt cttggtattc ccactaccac aagctgccaa agagatgaca cttaaaacag
     7261 acacaacccc tataacaaga tttttcttta acataacatt aacttcctcc taatttcttt
     7321 atggccattt ttctaatcaa gaaatattat gaactaccaa tgtaaatttc tagttaattt
     7381 tctgtaaata attcgaaatt tgtgcatttc ggggtacagg gtcactggac atatccatca
     7441 agctaagaat aaagccccca tatggtcatg tatcccatct ccaaatctct taactcctct
     7501 gttttgatta taaaatagtt tattctgtgc tcctttcttc cataaatagg cccatgcaca
     7561 acgtgaggtt atattataaa caccacagcg cgcaaggtac tcaatcgttt ctagttcatt
     7621 gactgtccat acagaaaatg tcaatcctag ctgctgcccc acttcacggg ccaacttagt
     7681 taaccatcct tcatgaatat tgacgatttg aacgctttga taggctaatt tctgtaaggt
     7741 atcgatcaaa tctgcttcgg taatatcccc aagttttttc ccttcgaact gattttcaat
     7801 attataaaat atatgctttc cccaaatcgc agcccaagat aattgtacat agccactaag
     7861 aacaatttgt ggccagattt gataggtttg tgccagcgaa aaaacggcca tttccaatcc
     7921 ctcttctttt aaatcacagt taatggtcat ggttgccttc tcattggcca ctgcttgaaa
     7981 cacctgctca agggttaccg aatctgggac aacttcttac ctgtcatggg ctagtattag
     8041 cgtaccatct gtttgctgac gcacatctac ttcaaaacaa agctggcgat ccaaacaaaa
     8101 gcgaagaaat gcccagctat tctcctccgt attgtcacta ccagagtgtg cagtgatcat
     8161 ggtcattttg acccctcctt taattccgtg attttctccc acacgtccac tataccgatg
     8221 aagcgttaat ttcttgttaa tttcttgtaa attccctgcg ttttttcagt aaactagttg
     8281 taaatcttgc atgctccttc ctacgaactc atgaatcgtc gattttgccc ttctagctag
     8341 tttcaccaat taagtagttc tacattcccc gcttttaacc tactacacct ttttttgttt
     8401 tcagctattc cttcttcttg ctgaaagtcc ttgaggttct ttcttacagg ataccatcaa
     8461 ggtgttcaat ggcttattcc cattgaatga ccgagactta ctatcagatt tctgctcgtt
     8521 gaaccaagtc tttgatacag gatttcttcc gtcatcttct cacaaatacc accttgcgtt
     8581 tctctagcga ttggtcgatg tgcaccctcc cagtggactg tcactacccc tttttgctat
     8641 gcctagccca caaaaaaagc tgtcctcaca gacag
//
LOCUS       DADGKS010000096         8629 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.100, whole genome shotgun sequence.
ACCESSION   DADGKS010000096 DADGKS010000000
VERSION     DADGKS010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8629)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8629)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8629
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.100"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            117..575
                     /locus_tag="JXV47_002543"
     CDS             117..575
                     /locus_tag="JXV47_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAX1488551.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            588..4625
                     /locus_tag="JXV47_002544"
     CDS             588..4625
                     /locus_tag="JXV47_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAX1488552.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            4625..5938
                     /locus_tag="JXV47_002545"
     CDS             4625..5938
                     /locus_tag="JXV47_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAX1488553.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            5931..7628
                     /locus_tag="JXV47_002546"
     CDS             5931..7628
                     /locus_tag="JXV47_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAX1488554.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            7702..8595
                     /locus_tag="JXV47_002547"
     CDS             7702..8595
                     /locus_tag="JXV47_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAX1488555.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
BASE COUNT         2979 a         1495 c         1983 g         2172 t
ORIGIN      
        1 ctaaaaagga tatcatttga tttaaaatta aaattaaatt aaattataat tagatgggca
       61 ttgttttgtt gattgttgtg aaagaagaca aatatttttg aaaggagtat aaggatgtga
      121 aagggttaaa attgaagctt ttgcagttag taactgtcag tttgctattt ggaccatatt
      181 tccagtcagt ctatcatatg acgaccctgg atgtagctgc tgagtcaaca gaaacaaagg
      241 aggatgaggt attcttagat gaggactatg caaaaattga agggaagtat attgaaaaag
      301 aagaaaccct tgaatggcat ctggcttttg aaaaaaagga aagtgccaat gaaggtagaa
      361 tacgtttagc aatcgatgcg gcagccgccg ggattggtac cgtaaaaaac gttcgtggaa
      421 caggtctatc ctcctatgat gaagatggag aagacctaaa agtcgagacg atcgatggtc
      481 aagaatggta tgtcggaaaa gtttattcaa aagaagcaga aaccggcaca ttgatttttg
      541 aaacagaaaa gatccccgat gtgaacgaag ggtaactacc tcttcaagtg gtggttgatg
      601 aaagaataga taaccaagaa ttacaagaaa atgaaactga tacagaagat tccgctgaaa
      661 ttcaacgtag cgaagaaaat gagatggaaa agctggacga accaatcgta cccagcggtc
      721 aagcactcca gcgcattcaa cgccagttat tcaacggtat tttggagcgt cttgggccaa
      781 cagctacgca agacccctat gaatatatct atcctagcgg agaagttgaa aacgaacagc
      841 atcgctaccc gaagtttaca acgaatgact atacaaaagt gttaggaaat tggacacaaa
      901 gcaatgaacg ctatcaagga gacaaaggct cgccatatga cggagagaac ttgatcgatg
      961 atagtgatta tacaaacggg ggagcgaact ggcgaaatta cgactatgct actaataatg
     1021 gatcaactgc aggcgaagaa gatagaaacg ttccagctca aaccgttcag ctttggggaa
     1081 atgaacggaa ttttgaaaac agttacttgg attataacgg ggcgtacatc aaaaaatggg
     1141 tagaacctgt tctgccaagc agcacagcat ctgatctaca tcctgaagat gcaacaaccc
     1201 tttacaatgt ctatctagat gtcatcgggg gcgagaaaaa ggaaatcagt ccaatcgata
     1261 tcgtttttgt tctagataag tcagcgagta tgagtgaatt aaccgctggg accaatagtc
     1321 aaactaaaaa tgctgcgttg attgaggcag taaacgaaat gagtaaagat ctgctctctg
     1381 acccgagtct ggatattcga atcggtatgg tgaattttta ccataatagt acagctatca
     1441 ataaccatga gcaaatcagt tcggacatct ttccattgac aaatgatatc aatcgtttga
     1501 cgggaagtga gaatacagca ttaaatcgta caccaatcgg aggaactccg cttacactag
     1561 ggcttaaaaa tggctatgaa acattgtata aagacaatgg cggagaaaat agaaatccag
     1621 aaaaaatcct aatcgttgtg ggagatggga caccgacctt cagttatgca ccgattcagt
     1681 caagttatcg tacgagcact aatggagctt ggagcaactg gactgtgatg gaagataaga
     1741 ttgctgaaga taatgacgtt ttgttcagaa attttgagga gttttctggg aatacttcta
     1801 atgcagggtt tactcatcca gttacctatg catctgactt taaccgtcca gaagatgaag
     1861 taaatgtaca ctatcgttat ggagaggtaa aagaaggaga taataaagcg actcactggg
     1921 ttggtgatgg ttcttctaat aacaatacga atggcagtcc tacttcgcaa gaaaagtcat
     1981 ctgcgatcaa cacagttgct tatcatcatt ggctgaaaaa caagtatcaa gagaacccgc
     2041 caagtatctt ctccattggt ttaggaatcg atggaaacgt tagcgggaga caacgactag
     2101 atgctattgg acgaaatgta ttgaaaaata ttgctgattt agaagaagat ggcgtaacac
     2161 cgcgatatta caatgcgaac aacaagaatg acattgttac agccttggag gatatctctt
     2221 ctaccttcaa gagaacgatc cagcaagcca cactttatga tgaaactggt tttaatgtct
     2281 caccatttgg agctggcaga tcggcagata ttcagtttta ccatctagat ccaggagaaa
     2341 acggcatgaa gtaccaagag ccagaaatat gggatgaaga acgtcatgga caagccccac
     2401 cagaagtagt ggcgactccg acaacgtatg tcggacggga aaaccaagct tataaatttt
     2461 ctccgatttc tttaggtgaa ggggaaatgg tcaggatcaa gtaccaagta aaacttgatg
     2521 cgggagctca agacggaaat ttttgcacag tgaacaatat ggcctatatt cagaacctgg
     2581 aggattatga gaatgatatc actactggac ggatgtattt cccatcttct tccattcgtt
     2641 acgaacataa aggccgtaat ttccaagtca gcaagaaggg tcaaaatggc gagccgttgg
     2701 ctggagtcga atttgcatta tatgaccaaa atccagagag tggggaagcc gaaccaatcg
     2761 aaacaagtaa aactaccacg gacggaatag cgatctttga aacgaagatg ccgattttag
     2821 gagatgaaac tggagcagtc agcgacatat tttggatcag agagatcgct ggaccaccac
     2881 gttatcagtt agtagatgag acgtatcaat tccaaatcaa aaaatatgca gccaacgaag
     2941 atgagatgtt aggtcactac gagcttgtag atgaatatac atctggttcg agagtcggcg
     3001 gaccggaagg taaagatccg aattcctatt atgaaggaga atatcacaag ctttctgttg
     3061 tacaagagcc taacatagaa ggcacagagt atgatgagtt gtatgtcaaa ctggaaatgc
     3121 gaaatgaatt caagccaatc cacatgaata tcaataaact aattgaaggc agtaatatgc
     3181 caatcaatgg cgcagagttt gaactttatg aaacagatgg taacggactg gaaatcggat
     3241 atccagtagc gaaagggctt tctggtgtga acgaagtaga ggaagagaaa gggagactca
     3301 cgttctattc agtagatgaa gacgggaaat atgtaatcgt ggatggtgag aaagttattc
     3361 atccaatcgg agagccagat tcatttgttt ataaggatag tgaagaaact accaactatg
     3421 cagaatacaa aatcattgag agccagaacc cagaaggttt caaagaacct gatgaaaatg
     3481 acacatggat cttgcgactt tacgataatg ctatagggac tatccaactc aagcaaacag
     3541 gtgaagaaaa ttggcaatat ctcacgtata caacagatga agaggatcgt ttatgggtag
     3601 cattcactgc ttacaatacg tttgattatc gggagatccg agttagaaaa ttagaccatg
     3661 aaggccatac attagatggt gcaggtttcg atatcaggaa agtgggggat tcttccttcc
     3721 cgctgtatcg agcatacact ggtaatccgt tagaaccaga agaatcgaaa cgtttgcctg
     3781 ggatcggata cttctattct cgtgccgtag gagtagaaaa gtatgtcgat ttaaattacg
     3841 accaacctct gcatctgtct attggtgaat atgaggtctc ggaatctgtc gcaccaaatg
     3901 ggtatcggct atctgatcaa gtgttccagt ttgcactgaa tgaagaaggt aagtttatca
     3961 ttgaagatac ggtcatcgaa gacgaaactg ctcccttgcc ggaaggctat gaaatcatcg
     4021 atggtgtact acaagtaacc ttagaagatg aactagcgcc aatcgatttg gaacttttga
     4081 aaattgacag tatgaatagc cgacgtcttg aaggcgcaga attttcaatt gagaaacaaa
     4141 atagtgcagg agagtatgaa atcatcgagg gaggcttggc accagatcca aacgattctt
     4201 ccctattcaa tgcttcagac ttgttggaag gggtctatcg gatcaaggaa gtgaagtcac
     4261 ctgacagcta tagaaaactt ccaggttact ttattttaga aattagttat cgagaagaac
     4321 ctgacataga aaatgatcgg gtagttccag gaaaagaagc gggtacacta aaagttgaga
     4381 tttcgtatta tccaaacgaa gaagcagaga cgcctgatct acagcaagag ttagaatatg
     4441 aacttttgga gacaaatcga atcagattac agcttagtgt cgggaacgat cctgaaaatc
     4501 cgttgcctgc tacaggagga tccggacgat tattctatat cctgcttgct gcattcttca
     4561 tggcgcttgc aggagcagcc tatggtttgt ttgtcagaca atctaaaaag gagggagcaa
     4621 ggtaatgaaa aagctgttgt gtttgatgct tcaattactt gttttactac cgcttgcagc
     4681 agtccttctt ccacatgcga tgtcggcaga agaatcaggg gaagatgtcg tggaattcgt
     4741 gttgcataaa cggatgattc gagatatcga ttataacgat caatttgaat accatgaaaa
     4801 tgatggcttg gctatctctg aggaagcagg ggaaacagca gatatcattt cacagacggt
     4861 gccactaaat ggagcgacat ttgccattta cgacatgacc gattattatc atgaaaaaaa
     4921 agctgctgaa aacatgactc ctaaagaatt cgtccagcaa atcgctgaaa cgaacagaaa
     4981 caatatccgt cagctaatca cagaagaaag gcttgtccaa atagggactt cggtaacaac
     5041 tgggaaagat acggttggcg gattaggaga cgggattgca cgtatcaaag cacctaagaa
     5101 aaaccaagat cgggatgcag tttatttgat tttcgaagaa tcgattgatc cagaagttgg
     5161 attggatgtt gatatcgatc agacagctat cccaattgct gctattttgc caatttatca
     5221 cccgacagaa tcaaccgagg aactgcaaga gattcatatc tatcctaaaa atgtcggtta
     5281 tctaagagat ccatacttct tcaagtatgg acgtcaaaga ggaacaactg aaaaaggaaa
     5341 accattagaa ggtgctgttt ttgctctata tcagatgata gaagggggga aatattattt
     5401 agatatggct cctgctaatg acttgaaaaa tcaatggatc aaaccagcag acaatgatcc
     5461 tttgaatgac aaaaatgtaa gcaaattcat ttcggataaa gagggccttg ttacgacagg
     5521 acaacgtttc ttgccttctg gcacctatta ttttgaagaa ttaaaaggtg tggaaggtta
     5581 cgagatggat gaagcaagta agagaatcga ggtcatcatc cctgaatttt gggtggatgc
     5641 aaaaggccaa ccacaatatg tagtagttaa cggacaggag atggctgaat tagaatccgg
     5701 gaaagttcca gtctctgcct atgaatccgc aacaccacgt gtttataacg agaccgtaaa
     5761 agaaacaacg gacaaaccga aagagccgag tggtccaagc aatccaggtc aatcaggaaa
     5821 atggtccgta ttcccgcaaa cgaatgaagc aagaacgttg atttctttac taggaattct
     5881 tttattgtta ggtgctgttt tattaataaa aaaagaacgg ggagaaaaaa atgaataaaa
     5941 aaatgattgt cacgggaatg agtgtactgt tactcgttac tgcgggaata gggattttcg
     6001 ggaacggaaa actagtcaaa gccgaagaag tcgcacaaaa accaagtgaa gtgacgatta
     6061 cattacacaa aaaaggtttc tcatctgttc cggaagaacg accgaatagc ggattggttt
     6121 ctacggattt tggtgaagaa aatattccag gagtcgattt tgatttgttt gacgtaacgg
     6181 aagtatatta cgatttgatt cgagataatc ctttaacacc ggaacgagaa gacggtctta
     6241 attctgccga agcgattgaa tggattcaaa aacggcacac agaaagttgg tttttaaaat
     6301 atcgactgac aagtattgac aaacaaacaa cgaatgaagc tggagaagcg gtattctcta
     6361 ccgtccaagt gacggaagaa gcaccttctt ctagagataa agtctatctt ttcttagaaa
     6421 cttattcgcc agctcatatt tccagaatcg cgtctccaat ggttgttatg atgccagtga
     6481 tgatgcctga tatggtggat ggcgtgtggg atggttctac atggaaagac acatacaata
     6541 cagatgtgca tttgtatccg aaaaacgaaa tcagagaagc agataaacag atgaatgtag
     6601 aggaaagcga ccttagacaa gtaacgatta ttaatgaagc tggagaacaa gaaacgattt
     6661 cttatattga tctagaaaga ggaaaaacgg cttcttacac gatcacagca cctattcctt
     6721 atttcatcga ttctgtcctt gaaaacggaa gcgctgttat caaaaattac aaaatcacag
     6781 atacgcctac agttggtcta acttattatg atcaggaaat agaagtgcga gccggcgaga
     6841 cgattttaac aaaaggacaa gattatatag tagaagtagt aagcaacggg tttgtcgtga
     6901 cgattttgac agaagaaaat ggagtagcca aagtagatac tttaggtaga ttagcagatg
     6961 cacgtggagg agatttaacg atcacgtata atttgaaggt ttccacagaa ctagaagcgg
     7021 atgatttcca taacaacaca gcggttattg aaatcggacg aaatgatgaa tttgattatg
     7081 aagaaggagt agagccgcca gagaaagtca caacaggtgg aagaaagttt gaaaaatatg
     7141 atgcatcaag cagtgaattg cttaaagatg caagattcga attgtggaat gaagaccgtt
     7201 ctgaatacgc aatattttat aaaggggagt cgcctttagc tgtttatgaa tcaggagcag
     7261 atagaattga gtgggcaaca agcggacaag caacagaatt tgtcgcagat ggaaatggat
     7321 actttgaggt tcaagggtta gattatggaa cctatcaaat gaaagagacc atggcgccag
     7381 aaggttatgt acttccaaca ggtgaggcag cctttactga atttatcatc tcttatggaa
     7441 gctataatga agaaattcag atcgtaggag tagaaaatcc agggccagaa agagtaccga
     7501 atatgaaacg cgggtcactt cctgctactg gtgggaacgg gctcttggca ttcttactaa
     7561 tcggaataag tttgatgatt ggagcgtaca gctggtaccg taaatctaaa atgaagtctg
     7621 aagtataagc aacaaaaata agctgcagca atcggtttta taaaggttgc tgcagttttt
     7681 ttaaataaga aggtgaagaa aatgaaaaag aaaataggta atagacctca aacccaaatc
     7741 agtcttttat tacaattatt tatggcagtg atgtttcttg ccggagctgc agtttttaca
     7801 tatccatttt tagcagatgc tctcagcaat tatttggatc aaagaaggat cgagaattat
     7861 caaaagcagc ttgaacgcga taaagaagaa aaacatgagc aacaattagc agtgcatgaa
     7921 aagaaaaatc agacgcttgc tcatacatca gtaatcccag gaatgggaca agtcaaagat
     7981 ccttttgagc aagcggttag aaatgtccaa aatccaggaa aagaatatta cgaacaacat
     8041 atgatcggag ccatctatat tccgaaaatc aatgttagct tgcctttatt tgatgaaacg
     8101 aatgatcttt tgttagatag aggagcgaca gtcctgcaag gcacctcttt tccaactgga
     8161 ggagagagta cacattccgt gattaccgcc catagcggta ttgctgagaa aaaactcttt
     8221 acggatcttg aagaaatgga gcaagatgac cgattctatc ttgaagtgta tggtcggatg
     8281 ctcgcttatg aagtcgttga gaaaattgtt gtccttccaa caaaaacaaa tacattagca
     8341 attagagaaa agcaggatct agtcacactt atcacttgta caccttacac cgtgaacact
     8401 caccgattac tagtgacagg aagacgagtt ccctttacag aagaagtctc ttcaaagata
     8461 gaacagacaa aaaaatacca tctttatcga ttacttatac tccttctagg tatattgcta
     8521 gtgctaacgc ttttcggtta ttggtgttat cgaaaattta aaagacaaaa acaacgaaag
     8581 aaaaataaca gataatagac caattattaa gaataacata ataaattta
//
LOCUS       DADGKS010000097         8590 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.101, whole genome shotgun sequence.
ACCESSION   DADGKS010000097 DADGKS010000000
VERSION     DADGKS010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.101"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(48..1514)
                     /locus_tag="JXV47_002548"
     CDS             complement(48..1514)
                     /locus_tag="JXV47_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HAX1488556.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
     gene            1902..2498
                     /locus_tag="JXV47_002549"
     CDS             1902..2498
                     /locus_tag="JXV47_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAX1488557.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
     gene            complement(2556..3038)
                     /locus_tag="JXV47_002550"
     CDS             complement(2556..3038)
                     /locus_tag="JXV47_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488558.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3144..3341)
                     /locus_tag="JXV47_002551"
     CDS             complement(3144..3341)
                     /locus_tag="JXV47_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488559.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3636..4394
                     /locus_tag="JXV47_002552"
     CDS             3636..4394
                     /locus_tag="JXV47_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HAX1488560.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4454..4882
                     /locus_tag="JXV47_002553"
     CDS             4454..4882
                     /locus_tag="JXV47_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488561.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4928..5000
                     /locus_tag="JXV47_002554"
     tRNA            4928..5000
                     /locus_tag="JXV47_002554"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4961..4963,aa:Gln,seq:ctg)
     gene            complement(5150..5521)
                     /locus_tag="JXV47_002555"
     CDS             complement(5150..5521)
                     /locus_tag="JXV47_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAX1488562.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5736..5921
                     /locus_tag="JXV47_002556"
     CDS             5736..5921
                     /locus_tag="JXV47_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488563.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(6004..6192)
                     /locus_tag="JXV47_002557"
     CDS             complement(6004..6192)
                     /locus_tag="JXV47_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488564.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(6216..6479)
                     /locus_tag="JXV47_002558"
     CDS             complement(6216..6479)
                     /locus_tag="JXV47_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488565.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            6637..6894
                     /locus_tag="JXV47_002559"
     CDS             6637..6894
                     /locus_tag="JXV47_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HAX1488566.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(6965..7156)
                     /locus_tag="JXV47_002560"
     CDS             complement(6965..7156)
                     /locus_tag="JXV47_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488567.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(7297..7617)
                     /locus_tag="JXV47_002561"
     CDS             complement(7297..7617)
                     /locus_tag="JXV47_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488568.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(7640..8074)
                     /locus_tag="JXV47_002562"
     CDS             complement(7640..8074)
                     /locus_tag="JXV47_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAX1488569.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            8409..>8590
                     /locus_tag="JXV47_002563"
     CDS             8409..>8590
                     /locus_tag="JXV47_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAX1488570.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
BASE COUNT         2722 a         1695 c         1361 g         2812 t
ORIGIN      
        1 aacaggaact gctgcaaata agcaattcct gtttttatgt tcattgatta atgaatagag
       61 cccattagtt ttttgattgg ttctttcaca gtaaatagca agataccacc gacgattgct
      121 actgcaccga taataccgaa gtaagcagat tctgttcccg gtgtgtagaa gcgtgcaatt
      181 tgtgcattga ttgcttgtga agaagcatca gctaagaacc aaatagcgat tgtttgtgat
      241 tcaaatgctc gtggtgctaa ttttgttgtc acagacaaac caactggtga aagacacaat
      301 tcagcaataa ccacgatgaa gaaacttccc aacaaccaca atggacttac ttttccactt
      361 gtaccataaa gcatacccgg caacatcaat agcaagtacg ataatcctgc aaataaaagt
      421 ccaagagaga atttcactac tgtagatggt tgacgttcac caagtttcgt ccacatcgtt
      481 acgaatactg gtgtcagaat aaagatgaaa attggattca atgattgata ccagcttgct
      541 tggatcgtta caccaaatag cgtagattgt gtacgttcac tagcaaataa agctaagata
      601 gatgaacctt gttcttgtaa tgaccagaaa atgattgctg caaggaataa tgggatataa
      661 gcccatactc ttggtttttc ttcagcagtt acatcttttg aagtcagcat tttgataaag
      721 taatacaacg gtaagataat ccccaataca ctgattgtat tgacaaaaaa gtcaattgtc
      781 agatgaccag ttagttgtgc cccgccgaat actgcagcga taacaacaag tgcgatgatc
      841 aagttacgga tgaatccttt acgttcttca gttgtcaaag gattcggcgg tgttgtaccc
      901 actccgtcta atgtcttgcg tccttggatg atgtattgta ataatccaaa gaacatccca
      961 atagcagcta aagagaaccc taaatgatag ttatattctt gaccgattgt accaacgatt
     1021 agtggtgcta ataatgcccc taagttgaca cccatgtaaa aaatcgaaaa tcctgcatct
     1081 cttcgcaagt cagtctttga ataaagatgt ccgaccatgc cagaaacatt tggtttcaaa
     1141 aaggcggttc cgataataat caatgccatc gaaacaaaca atgtacttac accaaatggt
     1201 aaagccaaga cgatgtggcc aagcataatg aaaactccac cgaagaatac agtgcgtttt
     1261 gctcctaaca ctcggtcaga tacccatccg ccgacgatac tagacatgta gatcaaagat
     1321 ccgtagatcg acatgatagc taatgctgtt gctcgtggta atccaagtcc cccgttggca
     1381 actgtatcgt acatataata gataagtaat gcacgcatac cgtaataact aaatcgttcc
     1441 cacatctcag tgaagaacaa agttgacaat cccttcggct gcccgaagaa gcccttgtct
     1501 tgctgttttt ccataatcta taccccaatt ctttaaattt tcagaaaata ttatacatct
     1561 ttaccgaaaa atttaactaa aaaacttatt taagaaatat aaactaattt tctataaaag
     1621 caagtaattt ttaatggcaa tatcataaaa aaaaagaaga tagagattta ataattatat
     1681 atcagctgtt tttttcaaat aagcaaaaat tcctaaaaca caacaatgaa agcgataact
     1741 aagaaaatcc ttacataacg atttttctta ttaaaattgt tttttgaact tcgcttattt
     1801 tttgtgagca tatctgttta cttacttttt gtaaggtgct atacttcatt tcgtaatcaa
     1861 ttaaaaaaat gcaaaacgca aatcaaagga gaaattttat tatgacaact tttactgaca
     1921 ctttgaaaaa ccgccgttca atctatcatc taggacgtaa tgtttcactt tctaatgaag
     1981 aattaacaac tttgatcaaa gaagcaatta aagaaagccc aactgctttc aatgctcaat
     2041 caacacgcgc agttatcctt ttcggagatg cacatgaaaa actttgggaa atcactgaag
     2101 aagcacttcg cccattgact ccagcagaag ctttcccaaa tacacaaaac aaattagctg
     2161 gtttcaaaaa tggttatggt acagtattat tcttcaaaga tactgacgtg gtaaaaggtc
     2221 tacaagaaca atttgaatta tatgcagaca acttcccaga ttggtcagaa caatcaaacg
     2281 gaatcgcaac agctaatact tgggtagcat tagttgataa aggattgggc gcaaacttgc
     2341 aacattacaa cccagttatt gacgaagcag ttgcaaaaga atggaatatc ccttcaaact
     2401 ggaaactacg ttcgcaatta gtattcggtt caccagaaac accggctgag gaaaaagaat
     2461 acatgaacga tgccgatcgc ttccgcgtat ttggataatt ttatttgaaa taaaaaacag
     2521 aggttgtgac aaacatcttg tcgcaacctc tgtttttatt ctggatcaat cataatatca
     2581 atctctgcct catcgtttaa gcgttgggac aaaaatggaa ctaattcttc taatgatgca
     2641 gaaaatttca gcatcggtcc tcgccatccg tttcggaaaa aattcatttt tacgatttta
     2701 gaaccttttg gctgatataa tacaatttta ttgatctcag aaaaaggaac accttttttg
     2761 tcaaagctat tcaaaacaag tccttcttct gtgattcctc tactgtccaa caaaaaacta
     2821 ataaaaatca ttgctgacaa gatccctttt gccaattcat ctgctgtagg atgactgatg
     2881 agtgtatacc aaatgactag tgacactaag aagggtatca ccaagtagac ccatcgattt
     2941 cgcacagtcc gataaataat ttcttttcga accagccaaa gaaataaaaa catcacaaca
     3001 acgaataaaa acaatagaac cgtaaagaat gttaccatga caactcgcct cgctttttct
     3061 tctccagaaa ataggaaaag aatactgatt taccttctca aagaaattgg acttgcagca
     3121 cgccgcacgt ccaattgttt tctttattca aatgtatcat attttgcaac aaccatgctt
     3181 gctttttcat ctaataattc ttggtcctct gcagcacatt gggcaacttt gaccacggcg
     3241 cagtttgtca tttttgatac aacttcacca atgaccgttt ttgtaaaacc aattggtttg
     3301 catgcatatt gttctcctaa attaatcatt tcttccgtca tcaaaatcct cctaaactgc
     3361 tggaactttt ctccacatta ccactgctat ttctttggag atttaactca ttgattttta
     3421 tttacagtta aaaatcaacc ttacaggcat tatagcgtac tgttttcgtt ttcacaatta
     3481 aaacagctgt tgtatttaga agaatttttt tcaaaaaatt aaaacatatt ccttaaaaac
     3541 taattatttc ctacatatta aaatataata cttccatttc caataaaaat acatttataa
     3601 taggaaagat aaacagctga aaagggagat ttcaaatgaa gaaaaaaacg ttcaaaaaac
     3661 tattgtttct agggggcaca gctgctcttt tattaagcgg tacaagttat tacctacata
     3721 tccattctcc agaacataca atgaacactg cacaaaaaag ttcaacacaa aaaacgaaaa
     3781 agacaaaaga gaaagcagaa gttttactag atgttccatt agagagccag tttgattctc
     3841 cttctttaga aaatggctgt gaagtcactt cgctttctat gcttttatct ttttatggtt
     3901 atgaaacaac taaaaaccag ttagctgagc aattggatta cgtccctgtt ttcaatgcag
     3961 atgggactca tggcgatcct aatgaaggat ttgttggtga tatcagtggc ggagactggg
     4021 ctatggtcgt ctatgttccc ccagttgcct cccttgctca gcaaatcgtc caaacggatt
     4081 atcacacttt tccaaaaacc gatgctcaac tcgatgatat caaaaaagca ctatctaaag
     4141 gaaatcctgt ctggacttct gtgactatca attttgaagt cccagatgaa actgatttta
     4201 tgacttggac cacaaataat ggagaagtaa gagtcactcc tcttgttcat gcttgtgtag
     4261 tcactggata tgacaaagaa aatatttatg tcaacgatcc ctatggtgta aaaaatcgag
     4321 cagtaccgat caacgatttt tcggcgattt tcactgcaat gggtggacag atgctaactt
     4381 tggagaaaag ctagtaattc aaacaaaaat cccttatact caagatacca aacctttgaa
     4441 gggagcgtag ataatggaaa aattcacaca taaaaaaatg gatccaaatg aaattccgat
     4501 tatttttgtc cgtgactgca agggaaatgt tcaaggtaaa gtctctatta atgagtggaa
     4561 cgagcgtcgc agacctgcta ccctcaatga actggaaatc aaattgtatc gtcaatctct
     4621 tgtttattac gcagatcaag agtacgagaa agccaccgat ttattgaaat ttctaattgc
     4681 tcgaacagag tatactcgct ttgaatatat tgaacgttta gcaaacatct atcatattat
     4741 gaatgaacct gtcaaagaat atcagttatt ggacaccgtc ttgtcagtag cagaactgat
     4801 tgcccttcct gctggattag aaaagaaact agtacgccgc cttttacgag taaagcaaca
     4861 actatccgat caagaaaaat aacttgcgtt tttttaggaa agtgctatga ttattttgtt
     4921 gaataaatgg gatgtagcca aactggtaag gcacttgact ctgaatcaag caattgtagg
     4981 ttcgaaccct gccatcccaa tttgatgtgc ttgctgaaaa aatgaacccc ctgtaaaaga
     5041 acaatctttt tgcaggggga ttattgtatt atttttacta cttgtattta gtttacataa
     5101 ttaaattatg aataataaaa tcgggcgtat tcttaataca aaaactgatt tacccaataa
     5161 ttgctaatgc tttctccgga actttttctc taggaacttc ctcatacgtt tctatgtgtg
     5221 ctcctttatt gctaattttc aaataatgat tttcttttaa cacagaaaga ccattaaatt
     5281 caaccgttcg ttctttccca ttggcatcag cagctttctg cacatacctt gctgtaccat
     5341 attcatttac ttcctctggt ttttgtgtct ttacatagac ctctcctttt tcaactaatg
     5401 gatttagctg atcaagtata ccagggattt ctccataact tccttcagta taatatttca
     5461 gtccaaatag caaaatacca ctaatcgccg ccagtccaat caaatattta atcactttca
     5521 tctttctacc tccttgttat atattcagta tatgggtcag ttaaagaaat tccatccgtc
     5581 ccaagttgga gatttttctc ctactttaga agcgagaatc gagtgttttt ttagtaaaaa
     5641 tgatcgttat ttgatattat tgacgtgtgg ataaatcagt ttttctcgtt ttgtccatgt
     5701 aaaaaatcat gttgatagca aaggatgtgt tcaaaatgaa tcaagaagaa ttatttcaaa
     5761 aagtcaagga aatgattaag aacggcaatt tcgatggcgc aaaacgattt atcgaagaac
     5821 ataaagaaca attaggacct tataaagaga aagcccaaaa tcttttaaaa gatgtaaata
     5881 tcgacagtgt caaaaacaaa tttaaaaatc tattcaaata agtaaaactt tcacttttgt
     5941 aaaatcaaag gaggacaatg ctgctgcatc gtcctccttt ggttcttttc tgaatacttc
     6001 atactaaaat aaacgtgtcg gatcgtaatg ataagtcaca ttgccgttca gtgaggcttt
     6061 tcccaccaca tatttacgat tctccaactt cagccacgct tctcgaaaag ccattaattc
     6121 ttctcttttt acatcaatct tttcgatttt tccatcgatc aaatcttgaa taagttgttc
     6181 atatggattc atttttttcc tccatctgct gtcaatcaat aagttgtaaa aataggttca
     6241 tatgcttttt tggtatctag atcttctctg actttgactg tcgtataaat aattttttct
     6301 actgggatac tataataact tccttcacca ttattgaatc ggtgaacgtc tttctttgct
     6361 aaaataccat ttattttatt cgtcagtaca cgttgttcga cactgttact tacaacatag
     6421 taaatcaccc gaatattatt gatcaaatgc aaatcgattt ctaacactac atgatccatg
     6481 aaaatcccac tccttctttc actttgatta tagcaagttt ctcctctaat ttcaaaatcg
     6541 atacagattt taccggataa atccacaaaa ctgcttgcgc catttcgcac aaagtgttat
     6601 tttgtatcat ggactttatt tatcggaggc aatagtatga tcgcgatcgg tcaatttgtt
     6661 ttttatattc ctttttttat tatgataagc attcttttct attacataaa atggacaaaa
     6721 aagaagtttt cagttttact ggcctcttta cctgctgtat attttactta tcaaattttt
     6781 tcttttaggc attgggaaac aacgtctgta ttaataacac acatcatcga attgacgctt
     6841 tcagtaattt ttcttattat ttggatctat tttttatata agaatcagaa ttgaatccct
     6901 cgcatgttta aaaagaaaac gattaaagat gcagcaaatt tctgccgatc tttaatcgtt
     6961 ttttctattc tgttatacca aaaaaatgtt tgaatcggtg aaggatcgtt ccttgtttta
     7021 attctataaa ttcttgtgcg atcgggtact tttcttccaa attttctttg ttcttttcga
     7081 tcaggctttt cgcttcttca tattttttat ctgcacatag tgcttttact tcctgtaata
     7141 cttttcctgc ttccatttgc ctcaccctct tgccatttta ttgctttaag ttttatttaa
     7201 gttatacgca ttattctagt ttcatcccaa ataacctttt ttcattttta ctcctcgaac
     7261 taatcagttt tctaaaggct gattggttcg tcttttttat ttttcctcca tttcattctg
     7321 ctcttctgtt aatttatcta atgctttgat tgatgctgcg gctcttgcat aatcatagct
     7381 gtataattcc ataaatttat caggcagaac aaaccacgct ggatgataac cgttagctgt
     7441 gacagggaat cctttatctt gttggttatc tccatcccat ctcagagcaa cacctttttt
     7501 tcctttccac tttactaaag cgatcgagta tcccttcttt gtttgtgtgc cgtcttcaat
     7561 aattgctaaa atttctattt tttcttttgg cgcacggact tcttgaggac gaaccatttt
     7621 ctattcctcc cttatctcat tacttcacga ccaacacact gcaaggggca tgtgatacga
     7681 cataagaagc ggtcgatcca actaatgctt gttgtatagc accttttcct gtcgctccca
     7741 taacgatcaa atcaatattt tcttgtccag ggatgacatt ggcaatcaaa tttcttggat
     7801 ctccagtttc aactattgcg tggatctcag caatgccgta ctctttggca tcattgattt
     7861 ttttcagcat ggctacttct gttctttgtt tttcatctgc atagattttt gaaaaggcat
     7921 aggcactatg ggtcagctca actttgttga tgattgacac gataaataag tgggcttcat
     7981 tgtcctttgc taagtcaagg gcttcagcga acgctttgat cgattgtctt gatccgtcaa
     8041 ctgctaccat gatgttctgg tatcttttac tcattggaac cgcctccttt ttcttttatt
     8101 gtaacatctc aagcaaaaat acaaaaaata tacgcaatat gtaaataaaa tgatgaacaa
     8161 aagcaatttc tttcaagtta tttatacatt tcttttctca tcagaacacc tgttctaatc
     8221 ccattatttc tgcattatgt gaaattcctc atcatttttc acatcgagcg aacatcattc
     8281 tgttacaaaa aacgtggatt tgtcataaat tgtcatgctt cttttaccta tgaaatattt
     8341 tcacgtgtta aagtattcct cgttgaacac aacaaataaa actttttaac gaataaagga
     8401 gatttttcat gacatcactt aaaactttac tttttggaac aactttggct gccggcgctg
     8461 cattcttcat gggaacgact gctcatgcgg acgaagctta taccgttcaa tcaggtgata
     8521 ctctatcaac gatttctcaa aaatacgttg gtgataactc cttgatcaat gccattgcag
     8581 aatcaaattc
//
LOCUS       DADGKS010000098         8493 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.102, whole genome shotgun sequence.
ACCESSION   DADGKS010000098 DADGKS010000000
VERSION     DADGKS010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.102"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..173)
                     /locus_tag="JXV47_002564"
     CDS             complement(<1..173)
                     /locus_tag="JXV47_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009325336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1488571.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFL"
     gene            complement(593..1714)
                     /locus_tag="JXV47_002565"
     CDS             complement(593..1714)
                     /locus_tag="JXV47_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HAX1488572.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVVDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYRPG"
     gene            2042..3451
                     /locus_tag="JXV47_002566"
     CDS             2042..3451
                     /locus_tag="JXV47_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HAX1488573.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /locus_tag="JXV47_002567"
     CDS             3448..4176
                     /locus_tag="JXV47_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAX1488574.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="JXV47_002568"
     CDS             complement(4304..5215)
                     /locus_tag="JXV47_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAX1488575.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="JXV47_002569"
     CDS             complement(5232..6239)
                     /locus_tag="JXV47_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAX1488576.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSIPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="JXV47_002570"
     CDS             complement(6236..8365)
                     /locus_tag="JXV47_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAX1488577.1"
                     /translation="MKKKLFRIVGIVFISIVTLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..8477)
                     /locus_tag="JXV47_002571"
     CDS             complement(8370..8477)
                     /locus_tag="JXV47_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488578.1"
                     /translation="MQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2600 a         1727 c         1486 g         2680 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtctgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccacca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggaattga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca gagtgacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg ttt
//
LOCUS       DADGKS010000099         8425 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.103, whole genome shotgun sequence.
ACCESSION   DADGKS010000099 DADGKS010000000
VERSION     DADGKS010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8425
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.103"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            471..2108
                     /locus_tag="JXV47_002572"
     CDS             471..2108
                     /locus_tag="JXV47_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAX1488579.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSMGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(2253..2993)
                     /gene="truA"
                     /locus_tag="JXV47_002573"
     CDS             complement(2253..2993)
                     /gene="truA"
                     /locus_tag="JXV47_002573"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAX1488580.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(3184..3819)
                     /locus_tag="JXV47_002574"
     CDS             complement(3184..3819)
                     /locus_tag="JXV47_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HAX1488581.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(3966..5207)
                     /gene="sstT"
                     /locus_tag="JXV47_002575"
     CDS             complement(3966..5207)
                     /gene="sstT"
                     /locus_tag="JXV47_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HAX1488582.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            5405..6401
                     /locus_tag="JXV47_002576"
                     /pseudo
     CDS             5405..6401
                     /locus_tag="JXV47_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            6417..>8425
                     /locus_tag="JXV47_002577"
     CDS             6417..>8425
                     /locus_tag="JXV47_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAX1488583.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKILTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQK"
BASE COUNT         2785 a         1547 c         1293 g         2800 t
ORIGIN      
        1 aactaatcag aatcgtacaa atatttaata accaaatata tagaacataa cttaatatta
       61 agttatttga aattccataa aaaacgactg caggaattat tgtaagaaaa ggataaaaat
      121 agttcagtcc atctccataa ttgttaaatg ttgtatagtt gattggccct tcaaaaatag
      181 aagataaccc tttgattcgt gaaagatgaa aagataaatc acctgttgta taaatttctt
      241 gagcatttct cataaaattt actgaatata aagtactaag taagataaga actactaaaa
      301 gaaatgcttt tttacttatt ttcatagatt tgttgttctc cttttttaat tctattttca
      361 gtatactaga attgtctttt tttaataagt tttgcgttaa atttttcata gcactagtat
      421 gatatactag aaaagaatca atttttatta cttttaaata ggagaaaaaa atgaaaaaaa
      481 acaaaaacca aataatagat atcattttta tgttatttct aagttttgct tacgtcatcc
      541 ctctattcat gtctatggga atctatcata gtgtcaatca ggatacttac tttcatttat
      601 ctcgaatcat aggactagat aatgtatgga gttctccagt aaacttcaat aacttcgatc
      661 atcatggaac aatgatgaat attttttatc catggcttac tctttatcca gcttttttat
      721 tttataaaat gatgggaaat cttgttttaa gttataatat ctactatttt tttatcactt
      781 ttttaacaat ggtcgtttct tatttttcta tgaaacaaat aaaaaacaat cgttatattt
      841 cgctgttatt ttcgattatt tatacatttt ccgcctatcg tgccattgac atattccatc
      901 gtgcttcatt gggagaagct gtcgctttaa catttttgcc tttgatacta atggggtgtt
      961 acgaaattta tattagagat taccaaaaat ggtactggtt gtctattggc atgacgctag
     1021 tagtgtatac tcatttactt tctgtcgcta tggtttctgt atttattgga ggaacgttgt
     1081 ttctttcttt ttatttttgg gaccaaaaaa tcgctagact cttaagtctt ttaaaagcta
     1141 ccgtcctcac ctttttttta agtgcgggat tcttaattcc ttttattcaa caatctagag
     1201 cacaagaatt gaaagtccca ctgggaaaag aattaagtgg tatggctcct agtgatatgc
     1261 tgacacacat tttaaataat aactataaca actatactat tggattattc ttatttctcg
     1321 gattgattgg tgcttttatt tttataaaaa aattaactgc tgatgattta tttattttct
     1381 ttcttggtgt atttgttctt ttttgttcaa ccaatttatt tccttggcaa ctttttaacc
     1441 atacaccagt taagagtcta caatttgtct ggcggttaaa tggtttttct tctttattta
     1501 tagcctatac gatgagtata gtgatctatt atattttttc tactaaaaat aattcatgga
     1561 aaataatggt ctttacgttt cttgcactaa tattgcatct ctcaggagta agcaattcta
     1621 tccatgctaa caaagattca ttaacactta tagcacctga agacgctgtt gctatagctg
     1681 aaaattacaa tcatactgat tatgcaaaca aagagtcaat ctatcatcct gatatgatta
     1741 ataatgatca atatttacta ggtaaccagg aaataaatcc aacaactcat tttatgagta
     1801 acaaacttac aattgaatta gataattcga ataataaaaa tactgtcttg acgacaccta
     1861 tttatcgtta taaagggcaa gtggcttcta ttaatggcaa actagtacaa acaaaattat
     1921 ctaagtttgg cacaactgaa ttaactattc ctccaggtat aaataaagtc gttattactt
     1981 atcagtacac aaaactagca attgcttcaa gatatttatc tatcgttact ttgattttat
     2041 ttttacttta tcgatttact ttttctaaac aaaaacaacc gagaagagaa gtacaacatt
     2101 ctcactagat ttttatttaa gaaagacttt ttagctgtac acataaacag gctaaaaagt
     2161 ctttttttat atttctttaa tttgcttcat acattattta acatcgatat ttatactgtg
     2221 aaacatgcgt ttcatccatt atcaaagtat ttttatcgat aataaacttc atccaaaaac
     2281 agaccttgtg cagggacggt ttctcctgca tgttgccgca ctttgctttc aaatatttca
     2341 tcgattgttt ctatcggcat ggcacctgtg ccgatttcta gtaatgtccc catgataatc
     2401 cgcaccattt tatataagaa tccgtctccg acaaaagtaa aatgaagcat ttctcccttt
     2461 cgttcgatag ataattcatc aatcgtacgc actgtggatt tttttgattt tttcaatgca
     2521 gaaaaaccaa tgaaatcatg tgtacccact aatttttcgc aagctgcatt cagcttgtcc
     2581 atatccaact cttgagggaa ataaaagctg tggtttcgct caaatgctga aggaatcacg
     2641 ttgttccaaa cataatagct gtattttttg cccaccgcat tatatcttga atggaagcgc
     2701 tcaggcattt cttcgattct tttgatgaca atatcccgcg gaaggtaacg attcataaag
     2761 tcgatcattt ctgccagtcc aatttctgtg tttgttttaa aatttgctac ttgtcctcgc
     2821 gcatgggtgc cagcatctgt tcttcctgat ccaataattt ctatctcttc atttgtcatc
     2881 tgatgcaata ctttttcgat ttttccttga atggttttat cgtcatctcc aagtctttgc
     2941 catcctgaat atctttttcc gtcatattcg attgtcaact tgatgtttct catattttag
     3001 tggctcctct gtcttccatt tggtcttctc tctacctttt taagattgta gcacaaaata
     3061 tagctccttt cttctctaaa acagaagcta tacaagaaaa ctgtggaaat atatatttca
     3121 gaaaaacaaa aaacagccac cggatgaagt atccgctgac tgttcaattt gacggctcaa
     3181 gttttactgt ttgagatgca agatactcaa ccaggcaatg ggcacataat taaagaaaaa
     3241 actgattctt tggcaaaaac ctattttatt cagtaatggc caagaattta tagaaggaat
     3301 tcttgccagt ccataaatcg ccgcaaaaag caaactgatc acagacagtc caaggtataa
     3361 gtggcttacg tccatttgcc cattttttcg atagatcaag aaaagaagaa ctggaaacaa
     3421 taaaaaacca ctgtaaccta aacctgatcc gatattatgg acccatgtcg agacattcca
     3481 cgaagattca tgggtattga tactgaacaa acctgtaaag atacaatcac ctataccata
     3541 gaacgcgatg gctgctgtaa ctagggtagc taacacacga gatgtactta caaatgcagc
     3601 atacaatgca ggcaatgaca ggatgaaaaa gatccctgaa accacagacc aaataagaaa
     3661 cgcttttctt acaggactgg aaacctctcc aaatacactg atcacgctct tcatttgatc
     3721 taattcagga taatacaatc ctaatacgta cggagtcaaa aaatcactca gcacgcctaa
     3781 taataaaaag aaaaaaccaa atttacgtaa aaaatccatg atacgcctcc aataacaatt
     3841 acctatgctt ttaattgtta ttataagcga ctttatcttg atttaacaga aacctctatt
     3901 tacacgaaca tctatataac tcattaaaaa ctcgaatcat tttaaaaata ctaaatatct
     3961 aacgttcaac gttcacttaa tccatctaaa caatctttca atttgatttt ttccccactt
     4021 cttttacgcg cgcctagctc tcctattgca gtaaacaaca gatcacttga cgaatttaag
     4081 gcagtttcca ttgaatcctg gataacaccg ataataaatc caataccgac gatttgcatc
     4141 gcgacatcat tagagatacc aaacaaacta catgctaatg gaatcaataa cagtgaaccg
     4201 cccgcaacac ctgaagctcc acaagcagct aaagcagaca aaatacataa aaggactttc
     4261 aaaacaaaag gtgcttcaat ccctaaagaa tgtacagcag tcaacgtcat caaggaaatg
     4321 gtaatcgcgg caccgcccat attgatcgta gcacctaacg ggatcgatat ggaataagac
     4381 tcttttgtca atttcaatct ttcagccaac atcatgttta tcgggatatt tgcggcagaa
     4441 cttcgggtaa agaaagcggg aagtgcgctt tctttcaaac aaaagaaaat caatggatag
     4501 ggattttctt taataaacaa aaacgtgagg aatgggtaca caactaatgc gacaaacagc
     4561 atcgtaccga tcaaaacaag taaaagctgc agatactctg ccaatccagc tattccagtc
     4621 gtagcaattg attgataaac caatcctaaa atccctatcg gagcaaatgc aataatcact
     4681 tgtacgactt gtgacaacgc tatagatatc tgatccacca actcttttgt cgattctgaa
     4741 cgtgctcgaa aagctagtcc caacaataca gcccagaata agacgccaag gtaattcgca
     4801 tcaataagag attgaacagg attttgtgtg acattcgtca acatagtaga taaaacactt
     4861 tccaaacttt gcggtgcttt ttcagatact gtttcttgta aagtaatagg aacagtaaaa
     4921 attgaactta caataactgc tacaagtgca gaaagcaatg ttcccactaa atataagatc
     4981 aaaataggct tcacgaatgt cttattccca attttatgct tggcaattga cgccatcgtc
     5041 aagaaaaaaa ccagaatagg tgcgattgcc ttcaagcaac tgacaaacaa cgttcccaat
     5101 attgaaataa atgtccatgt ggggaaaaag ataccaaaca atattccgac taaaatacca
     5161 acaacaatac gttgaactaa cgacatatcc aaaaacttct ctaacaaatg accacccttt
     5221 cacaatttta acaatcattg tatcatttta tgcaaagaaa ctaaaggtat aattttctaa
     5281 aaattctaac aatacaaaca accatttctt gctaattttg tactttttct gtctacacgt
     5341 tgttttttga gatattctaa gttaggatgt tattaatggg caacttatca ggaaacgttt
     5401 tcttatgttt ttgtccaatt tttttgtgag gtgtttattc ttgaaaaaaa taaagaagga
     5461 gagttatggc ttcctgacaa tctttgtcgc ttgtataatg atggttttac agcgtatatt
     5521 gatttcagca gtcactattc ctacatatgc aacaaaccct ggtcgattct acatctatac
     5581 atttttacaa acttccgttg ttattggtgc aaatttgatc ccactttaca tgggttacca
     5641 atatcaaaaa atcgcccgtt taaaagtttt acattattta agtcgttttg cctttatatt
     5701 cctaatagcc acactagttt gcaatatctt ttttttacgt acaagctggc agcttgaata
     5761 ttcgtgatta ttggcttatc ctaacaccta tcagtcagaa ttactttact tatgctgttt
     5821 cttgtacttt gcttttttgt agtattcctt atacagttgg atttttaaat aaattatcga
     5881 aaacaacaat taaatatcta ctattatttt taacaattgg attagttggc tgctctactc
     5941 tatttaataa agacccgttt gcattacaga atggacagag tattttatgg attttttatt
     6001 tatttttaat gggttatggt ttgaaagaat ggaactggaa agaaaaggtc cgctataagc
     6061 ttcctcaagt atttatcagc ttgattgttt tattcggttt gattattttg atgacacaaa
     6121 tttcactcat catcagagga aatacagata cagcgctgag gttttctaaa ccatattctc
     6181 tcttcgcaat gtattatact ttctcttcgt ttttattttt agaaatgcta tctgataaat
     6241 taggtataaa aggaagagga aattttcttg ctgtattttt gattgtcact caagttatat
     6301 gtaatttccc tttagtttct tatcgcgtat ctacatttat gaaacgtgaa tttccaaact
     6361 cagggaaggc atggctgata aatatcgggc agttttttat ttgctattta ttagcagtgt
     6421 ccctcctagt tatcttttta ttttatatac aaaaaatccg tttcattcat cgtttcatcg
     6481 aatacttcgc ttttgattcg attgaacaat taactcagcg ttggaaaaaa agaattcatt
     6541 ggctttttgt tcataaaagt tattttttag ttgcagcatt tttttactgc tttaccttcg
     6601 tgcagatttt cgttttagaa ccaaaagaag gttggaaaga aactatccag gttgccttaa
     6661 aaatatttac tcagcgacaa gcacccatga tcctgacaat catcattatt atgggatttt
     6721 tcttcttact attgttgatt tccaatcgtt tttggtacgc cttgactgct accttgatca
     6781 ttaacttact gctcactatt tcgacagtaa tcaaaatgga aatgcgggaa gagcctgtct
     6841 ttccttcaga tttaaaaata ctgaccggat tgtcagaact attatcgatg gttagcccag
     6901 tcttattaat cgtgggcgga ttgatccttc tcctattatt gattactagt attattgtac
     6961 aacgtagact acaaaaacag tattccttga agattcattg gaaacgtcga tttatcagta
     7021 tcgctgtatt attaggatgt ttttcgggtg tctttttcat taatcacaaa aattcgcctt
     7081 ctttcttgct gtttaattta tttaaagtaa acaagacttt ctttaaccag caaggcgccg
     7141 taaaagataa cggaccagtc attcaattcc taaacaatat cgacattaaa atcatggaag
     7201 aacctgctgg ctattcgaaa gaaaaaatta atggaataat gaaaaagtac aacacaaagg
     7261 cagatgaaat caaccaaaca agaagtgact ggttaaacaa tcagacgatc gttctcaatt
     7321 taagtgaaag cttcagtgat cctgcacgtg tccctaatct gacagtacct acagacccta
     7381 ttccttacat caaaagcatt ataacagaag gaacaggagg attgatgtta tccgtcggtt
     7441 atggtggcgg aacagctaac atggaatggg aaggactgac aggcttgagt atcagtaacc
     7501 tgtctgcttc gttagttaca ccttataccc agctagtgga gcgtcagaaa ataagtccaa
     7561 atattaccga tctattcgat gaaaaaatag ccatccatcc ttttacagct gctctttatc
     7621 gcagaaaaca agtgtttgat aaatttggtt ttgacaggtt ctattattta gacagtccgg
     7681 ataaattaac ttatacggat aaaatagaac aaagcccacg catatcggat gattcagcat
     7741 acaaagaaac cttgaaagct ttacaaagca atacagaaac gtcacaattc atccaattat
     7801 ccactatgca aaaccatatg ccttatgatg attactatag tgaattgaac tacactgctg
     7861 aaggaactgc tgtcattcct aatagaagaa aagaattaca aacttatatg caaggccttc
     7921 actataccga tacagcagta aaaaaattca tccaagaaat cgacaaaatc gataaaccga
     7981 ttacctttgt tttttatggt gaccatttac ccgcaatcta tagtgggaat gattcgaaaa
     8041 aatatggatt agaacagcac cagacagatt atttcattta taacaacaag tatagtcgtg
     8101 aacaagcagc tacgttaaat aaagaagttg ttgctcctaa taactttggt gctatggctc
     8161 ttgagcatgc gaatatcaaa gtaactcctt actatgcgtt gttgacagaa gtatctaatc
     8221 atctacctgc attaacaatt gatcctacag aaagcttgtc taatcgtttt aatggaaaac
     8281 aggtctttgt tacagaggat agtcaaatta tccaagaaaa aaatttaact gagaaacaaa
     8341 aagaaattct agaagattat cgtctgatac aatatgatct tgttgcaggt aaccagtaca
     8401 gtgcaacatg ggcgacacaa aaaat
//
LOCUS       DADGKS010000100         8287 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.104, whole genome shotgun sequence.
ACCESSION   DADGKS010000100 DADGKS010000000
VERSION     DADGKS010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8287
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.104"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            167..1240
                     /locus_tag="JXV47_002578"
     CDS             167..1240
                     /locus_tag="JXV47_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAX1488584.1"
                     /translation="MIELRDISVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEAGK
                     IIEKGSSIQIFSHPEEELTKDFIRTATHLDQALETISAHAAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRQKALDYLIKS
                     GVKVTILQKNELDNRIKVIEGGN"
     gene            1242..1922
                     /locus_tag="JXV47_002579"
     CDS             1242..1922
                     /locus_tag="JXV47_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1488585.1"
                     /translation="MTEFFKTYLPNVYLIPDEFIEATKQTLYMSFWTAFIGGIIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILVLVFLSQFISN
                     QLIKKVTH"
     gene            1939..2778
                     /locus_tag="JXV47_002580"
     CDS             1939..2778
                     /locus_tag="JXV47_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HAX1488586.1"
                     /translation="MKKIIRFAVITFVAIIWLAGCSQGKAATTEKKETTVKLGIIGED
                     TDVWDDVKDRLKKENIHLEYVKFTDYNQPNAALADGSIDLNSFQHQFFLDNYNEEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENKKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDEHARPYVNIIVARKEDEDNKTYQKIVDAYQTEETAKVIEKTSKGSSVPAWETF
                     GRK"
     gene            2810..4033
                     /locus_tag="JXV47_002581"
     CDS             2810..4033
                     /locus_tag="JXV47_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HAX1488587.1"
                     /translation="MTTTLSTNQLKDLIQYRLPEYQALALAIHDHPEVSNYEFYSSAA
                     LIKQLEKEGFWVEKEVAGHRTGFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDEIGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDAALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAALSTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSEKGLASIAIAAELLANTALDLLREPKLLEKIKQE
                     HQEIVARKKQEGATF"
     gene            4437..5855
                     /gene="nhaC"
                     /locus_tag="JXV47_002582"
     CDS             4437..5855
                     /gene="nhaC"
                     /locus_tag="JXV47_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAX1488588.1"
                     /translation="MEKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKKYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDILEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPKLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(6117..6560)
                     /locus_tag="JXV47_002583"
     CDS             complement(6117..6560)
                     /locus_tag="JXV47_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HAX1488589.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINAMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILTSKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(6755..8095)
                     /locus_tag="JXV47_002584"
     CDS             complement(6755..8095)
                     /locus_tag="JXV47_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAX1488590.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGIILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHAADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFAAYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLIIFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLTLRKGTLW
                     DKGISFFALAVLWLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
BASE COUNT         2722 a         1511 c         1690 g         2364 t
ORIGIN      
        1 tgacggctgc gaccgatatc ttgctagagt atgatggtac ttgaagagga gttgtgtgtg
       61 aacacagctt gaacatgagg tggtaacacg caaaaaggcg tcctcaagaa aatgactatt
      121 ttcattttct tgaggatgct ttttttatag acaaggagga atgttaatga ttgaattgcg
      181 agatatttct gtatgtttca aacaaaaaga aaaagagata caggcagtag attctgtaga
      241 tttaacgatt gaaaaagggg atgtttatgg gatcgtcggt tactcaggtg caggaaagag
      301 tacgttagtc cgcgtgatga atttgttgca gaaaccaaca gcaggagaag tcatcgtcaa
      361 tcagacgaat ttaagccagc tctctccaaa agaattgcga aaagaaagaa aggccatcgg
      421 tatgatcttt cagcatttca atctaatgga aagtcgaacg atttttgaca acgtagattt
      481 ttctctaaag tattctggaa aatcaaaaca ggaacgtcgt caaaaagtga atgaactact
      541 ggaacttgtc ggtctggaag aaaaagcatc tgcgtatcct aaacaactgt cgggggggca
      601 aaaacaacga gtggcaatcg cacgagctct ggcaaatgaa cctaaagtgt tgttatgcga
      661 tgaagcaact agtgcacttg atccgaaaac gacccttcag atccttgcac tgttaaaaaa
      721 actaaatcgt cagctaggtc taacaatcgt cctgatcact catgagatgc aagttgtcaa
      781 agaaatctgc aacaaggtag cggttatgga agcggggaaa atcattgaaa aaggtagcag
      841 catccagatt ttcagtcatc ctgaagaaga attgactaaa gattttattc ggacagcgac
      901 acaccttgac caagcattgg aaacaatcag tgcccatgct gcttttgccg atcagattgc
      961 aaataaatgg ttggtggaat taagttatat cggcaaccag acgaacgaac ctctaatcgc
     1021 tcatctttac agcaagtacc aagtaacagc gaatatctta tacggtaatg tagagctatt
     1081 acaagaaaca cccttaggaa gtttgatcgt tactttagct ggagaaacca aacagcggca
     1141 aaaagcattg gattatttga ttaaatctgg tgtaaaagta actattttac aaaaaaatga
     1201 attagataac cgtatcaaag tcatcgaagg aggaaactaa aatgactgaa ttttttaaaa
     1261 catatttgcc gaatgtctat ttgattccgg atgaattcat cgaagcgaca aagcaaacac
     1321 tatatatgtc tttttggacg gcattcattg gtgggatcat cggaatcatc ttaggtgtga
     1381 cgttagtagt gacacgtcca aatggattac tagctaacag gctgctgttc gaaatacttg
     1441 ataagttgat caatatcatt cgttccatcc ctttcattat cttgctttct cttttagctt
     1501 tgactactcg tttcttagtt ggaacgacga ttggtgccaa agcagcttta gtccctttga
     1561 tttttggcgt tgtcccgttt tttgcccgtc aaatcgagaa tgcactgcta gaagttgatc
     1621 ctggggtgat cgaagcagca gaagcgatgg gcacgagccc aatcggcatc attttacgtg
     1681 tttatttgtt agaagggtta cctggtatca ttcgggtctc agcgttgacg atcatcaatg
     1741 tgatcggact gactaccatg gctggagcag taggtgccgg aggattaggg aatcttgcta
     1801 tatcgagagg atataatcga ttccaaacag atgtaacgat tgtcgctaca ttattgattc
     1861 tggtcttagt ttttttgagt caatttatca gtaatcaact gattaaaaaa gtcacacatt
     1921 gaaaatggag gagaaaaaat gaaaaaaatt attcgttttg cagtcattac atttgtagca
     1981 attatttggt tggcaggatg cagccaagga aaagcagcta caactgaaaa aaaagaaacg
     2041 accgtaaaac tagggatcat tggggaagat acagatgtat gggacgatgt gaaagaccgt
     2101 ttgaaaaagg aaaacatcca tttggaatat gtgaaattta cagattacaa tcagccaaat
     2161 gcggctttag cagatggatc gatcgatttg aattccttcc aacatcaatt ctttttagac
     2221 aattacaatg aagaacacgg aactgattta gtatcgattg ggaatacggt taatgcaccg
     2281 ttgggaattt attccaatac gttaaaagat gtggctgata tcaaagatgg agcaaaagtt
     2341 gcaatcccta atgatgtcac gaatggcggc agagctcttc tgttattgca aactgctgga
     2401 ttgatcaaag tggacaaggc aaaaggccaa gcgcctaccg tttctgatat taccgagaat
     2461 aaaaaaaatc tagacatttc tgagttagat gcttcccaaa cagcacgtgc tttgtcagat
     2521 gtagatattt cagtcatcaa tagcggtgta gctgtagatg ctggatttaa tcccgcttct
     2581 gatgcaatct tcttagaacc agtcgatgag catgcacgtc cttatgtcaa tatcatcgtt
     2641 gcaagaaaag aagatgaaga caataaaacg tatcaaaaaa tagtagatgc ctatcaaaca
     2701 gaagaaacag ccaaagtaat cgaaaaaaca tcaaaaggtt caagcgtacc tgcgtgggaa
     2761 acattcggga gaaaataaga aaaaacgact agcataggag gaaattttta tgacaaccac
     2821 actctcaaca aatcaattga aggatctgat tcaataccgt ttaccagaat atcaagcact
     2881 tgcactagct atccacgacc atcctgaagt aagtaattat gaattttatt cctcagcagc
     2941 tttaatcaaa caattggaaa aagaagggtt ctgggtagaa aaagaagtag ctgggcaccg
     3001 aacaggcttt gatgcacgtt atatttccaa taaaccaggt ccgacaattg cctttttggc
     3061 agaatttgat gctttaccag gtattggtca tgcatgcgga cataatttat ttggtactta
     3121 ctccgtatta gcagccagca tagtgaaaca attcattgat gagattggcg gagaaattcg
     3181 tgtgtatggt actccggggg aagaaggagg cgaaaatgga tcagctaagg gaagcttcgt
     3241 tcgggaaggt ttttttgagg atgtcgatgc agcattatgt gtccatccag cttttcgtta
     3301 tgggaaaacg acagaatctt tagcaaatga tccagtcgat atcaaatttt acggtgtcgc
     3361 ttctcatgca gcagcagcac ctgaaaaagg agtaaatgct ttggaagcct tgatccaagt
     3421 gtttaacgga atcaacgctc tacgcttgca attgccaaaa gatgtcaata tccatggaat
     3481 cattacagat ggaggcgtgg cggccaatgt cataccagac tacgctgctg gacgtttcta
     3541 tttacgtgca ggaaatcgac aaacattaga caaagtatat gaaaaagtgg aaaatatcgt
     3601 acgaggtgct gcattaagca cgggtacgac ttttgagttt ggattgttcc aaaatgcagt
     3661 cgatgatgtc atcgtaacgc cttctttcga tgacttattc ttccaacatg caaaagaagc
     3721 aggggttcct gatgaagaaa tagaaacgga acaaagaaca agtctaggtt cttctgatgt
     3781 aggaaatgtt agccaagtta ttccaacgat acagcctact gtagcaatct ctgagacata
     3841 tattgccgga catacagaag aattcaaagc tgctgctaaa agtgaaaaag gacttgcttc
     3901 tattgcgatt gcagcggaat tacttgccaa tacagctcta gatttattga gagaacccaa
     3961 gctattagaa aaaatcaaac aagaacatca agaaatagta gcaagaaaaa aacaagaggg
     4021 cgctactttc tagtaaaaag ataaagttgt gcgcgaaagt tataaaaata attttcagaa
     4081 aaatgaaaaa atattttctt tttcattgac aaatgatctt atggaaggta aacttcatac
     4141 aagtcaactt ttcacgcagt agtggttagg tgttttgttc agaaagtcgg tggtcgctgt
     4201 gaaccgatca agcctaattg acgaattaca tggaaagtcc atacatttga ataatcgttt
     4261 gaaagtgaaa aacagatctg tttttaatta aggtggtacc gcggagtcat tcgtccttag
     4321 ttgaaagcag gtctttttat ttttataaag gaggaatcgc ggatgaattg tggcggagta
     4381 atccgatatc ttaacttttt tagaacataa gaacaactaa aaaaggagag attatcatgg
     4441 aaaaaaaagg aacaccaagt tttttagaag caacacttgt attgatggtc attgttttag
     4501 gcattgcgat tggcgttgtc ggattaaagg tttcacctaa tatcacgatt ttggcagcta
     4561 tcggaatggt catgttgtac gcagtgataa aaaaataccc gacagattgg ctgcacgaag
     4621 ggatcatcaa tggcatcaaa ccggggatca ttccaatctt tatttttatt ttagtcggtt
     4681 cattgattgc tgtatggata caagcaggaa ttattccaac cctcatggtc attggattta
     4741 aattgattag tgtccagtgg ttcgtccctt ctgtatttgt tgtttgtgca atcgtaggta
     4801 gcgctgtagg gagtgccttt actgttatgt caacgattgg gattgcattt ttcggtattg
     4861 ggacaacact aggactaaat ccagcccttg ttgttggagc cattgtttca ggtgccgttt
     4921 ttggagacaa gatgtctcca ttatccgaat caacaaattt agcagcagct attgttgatg
     4981 ccgatttgtt caaacacatc aagcatatga tgtggtcaac tgttccggca tttgttgttt
     5041 ctttcttttt attcatgatt ttaggacaca caagtaaagc cgcaagtctt tcatctattc
     5101 gtgaagtgac tgatatttta gaagcaaact ttactatttc gatctggtca ctgattcctc
     5161 tatttttaat gctcttgtgt gcatggaaaa aggtaccggc aattttgacg attttgttga
     5221 atattgctgt agcagtagga atgatcttta ttcaaaaccc acaaacttcc ttaacgaagt
     5281 tggcaggggt catcgaatcg ggatttgttt caaatactgg aaaccaacaa atcgattcac
     5341 tacttagccg tggaggaatc gaaagcatga tgccaactgt gtcattgatt attctaacat
     5401 tgtcattagg tggtttgttg atcgaatttg ggttgatctc aaccgttatg gaacgagtat
     5461 caagaaagat gacgaacacc ccaaaattga tttttacaac attgatgaca agcatcggag
     5521 taaatatctt tattggagaa caatttctat ctgttatcct gcctggtaat gcatttaaag
     5581 aaacttacga aaaagcagga tttgatccaa ctgtattagg gagaacacta gaagatggtg
     5641 gaacagtaat caactactta gtgccttggg gaatcgccgg aagtttcgta gcaagtacat
     5701 ttggcattcc tacactcact tacttgccat tcgtgttttt cagtttgctt tcacctgtgt
     5761 tttcgatggt cagtgccttt acaggttggg ggatctcaaa gaaatttgtg aaaccgcaag
     5821 aagcagtaag caagacagcg caattagaac aataaaaacg taaaaaggga gtgtgacaag
     5881 acttttgtca cactcccttt tacgaacaaa cggtgttcaa aagcttgcat ttgcggtaat
     5941 aagcctaacc aaacgaaaaa tatgagaagc tatttttgtt tggctgttct tattacttga
     6001 tgcagggcag ctttttcaca acctctgatt cacggtgttc cagaagtagc ttcttcttat
     6061 ttcttgaagt tgatcacttc tggaacatcc tcttttttta tttggatgga taatggtcat
     6121 tccatttctt tgatcatttt tttcattttg tcgatttctt cttcttgtgc ctgaatgatt
     6181 tcttccgcta atttttttac ttcaggatct tttaaatcag ctcgtttact tgtcaagata
     6241 gcaatagagt gatgagggat catcgccttc atccacgccg tatcgttgac agttgtttgg
     6301 cttcgtacca taaataagga accggcaaaa acaagaagac tagcggctaa aatcatagca
     6361 tttatctttt tgttttcata cattttccac atgaacaaca acatgatgac tgccatgact
     6421 gcacccatca tcaacgccat gaatacacgt gtgcgactga agaagatatg atcaagcgca
     6481 taaacattca aatacatcat accaaacatg actaccgtcg aaacaccaat catcaacaaa
     6541 aacttccaat actttttcat ttaaaacaaa ctcctttttc ttcattcctt tcttctatca
     6601 tgtcatgagc gtggagaaca atcaattaat ctgcacagat ggtttttgaa caccgtttat
     6661 tcggaaaaaa gaactgcaac aatttttgtc gcagctcctt tttttcaata gctccagata
     6721 ttcaatataa atagaataaa attctctatt ggtttcattc attcgtcaag acgaaagcat
     6781 cattcttttt ttgataactg aaataaatga acaggtaaag caaaccggtc aatacagtta
     6841 ccccaatgga gttcgtgaat aggataccaa ggaaaatcaa ccataagact gctaatgcaa
     6901 aaaagctgat tcctttgtcc cataacgttc ctttccttag tgtcagtaca aaggacgcag
     6961 cactgataat gatccagatc aataatactg tataggaaag agaacctgcc agatagccaa
     7021 ataatttgtc accgacaaaa taagaaagag ccacacctag ataaagaaca ctggtacaaa
     7081 acagcacagc acgttgcggt acttgatgct tgtttaaaac agctagtttt ctagaggaac
     7141 ctttccgatc tttcaagcgg aagaacaaaa ttctcgaaga agcatataca cctgaattga
     7201 tagacgagaa cagagcaaga acaatcacga aattgacgat atctgccgca aatggaatat
     7261 tcattttttc aaataccatc acaaaaggac taacgttcgt gcctgctaaa gtattccaag
     7321 gaaaaataat caaaagcaaa aataaaggaa taatgtaaaa ggaaatgatt cttcccatga
     7381 cgcctttgat tgctttagga atcgcacgtt taggatcatc tgcttcgctt actgtgatag
     7441 caatcaactc agaaccgccg taagaataga taactacaag caaagaactg atgattccct
     7501 tcataccgtg gggagtaaaa ccaccatgat cagttaattg ttgaagggta gggaaaacac
     7561 cagtacccaa catttgctga ccgacaagat aagcagcaaa aatgatcaat aggataatga
     7621 cactgatttt agcaaaggcc agccaatatt ctgtctctgc gaataatcgt accgaataaa
     7681 gattgatgat agtagttaaa acagccaaca taaaaacaaa tacccaagct gggatgtggg
     7741 ggaaccacaa ctgtaaaaag gaagcagctg caacagcttc agcaatgata ttgataatcc
     7801 acatggacca gtagacccaa tcggtaaaat cggcagcatg agcacctaga tatggacgaa
     7861 tcaatccaga taatccgtgg tgcgtatcac caccacttaa aacaattttt cccagacctt
     7921 tcatcacgat atataaaatt atgccgccaa tcaaaaaagc gatcaataca gaagggccgg
     7981 cgattccaat cgcttcgcca cttcctttaa atagacctgc accaatcgct ccacctaaag
     8041 ctagcatggt gatatgtcgg gagctaagtt gttttttcaa ttttttatct tccataaata
     8101 acctctttct tttaaattca caatcaaaat gcatagtaag aataaatagt aagaataaat
     8161 agtaataata ataatgacta atgataacaa attttcagat aattacaact attcagaaaa
     8221 cttttgggca tattttaatg gaagaatgat ttatttcatc gtattttcat agaaatgtta
     8281 aattttt
//
LOCUS       DADGKS010000101         8278 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.105, whole genome shotgun sequence.
ACCESSION   DADGKS010000101 DADGKS010000000
VERSION     DADGKS010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8278
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.105"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..177
                     /locus_tag="JXV47_002585"
     CDS             <1..177
                     /locus_tag="JXV47_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488591.1"
                     /translation="QSLVLLAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGV
                     KDVLLSLFNRIVGA"
     gene            190..693
                     /locus_tag="JXV47_002586"
     CDS             190..693
                     /locus_tag="JXV47_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAX1488592.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            753..1142
                     /locus_tag="JXV47_002587"
     CDS             753..1142
                     /locus_tag="JXV47_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAX1488593.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            1129..3576
                     /locus_tag="JXV47_002588"
     CDS             1129..3576
                     /locus_tag="JXV47_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAX1488594.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            3581..5704
                     /locus_tag="JXV47_002589"
     CDS             3581..5704
                     /locus_tag="JXV47_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAX1488595.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            5701..6705
                     /locus_tag="JXV47_002590"
     CDS             5701..6705
                     /locus_tag="JXV47_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAX1488596.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            6724..7635
                     /locus_tag="JXV47_002591"
     CDS             6724..7635
                     /locus_tag="JXV47_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAX1488597.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            7822..8078
                     /locus_tag="JXV47_002592"
                     /pseudo
     CDS             7822..8078
                     /locus_tag="JXV47_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
BASE COUNT         2647 a         1380 c         1841 g         2410 t
ORIGIN      
        1 caatccttag tcttactggc aattgtggtc attggtttgt ttttaggatt taagcgggag
       61 ttttccaaac tgattggctt tttggtgatt gctttgattg cggtcggatt ggtctttaat
      121 gcttctgggg tgaaggatgt cttactcagt ttgtttaacc gaattgtcgg tgcgtaaggg
      181 ggaagcacga tggaacagat gcgtgtttat attgcgaacc tcgggaaata taacgaaggt
      241 gaattggtgg gggcgtggtt taccccacct gtcgattttg atgaagtgaa agaacgaatt
      301 gggttaaatg acgaatacga ggaatatgca attcatgatt atgaacttcc ctttgagatt
      361 gatgagtata cgccaattga ggaaattaat cggttgtgtg gcttagcgga ggaacttgaa
      421 ggaacgccag ttggtgaagt tgcttctgag attcaacatg ctttcttcaa ttcttttgag
      481 gagatggtag agcatgtgga tgatattatc tattatccag attgcgatga tatgagtgat
      541 gtagcatatt tcttgattgt agaagctggt gattttggag aagtaccaga acacttgaag
      601 acgtatattg attttgatgc gtgtggtaga gacttggaga ttggaggcaa ttatttggta
      661 acgagtcgag gtgtttttga gtatccatat taacaaaatt attgaagggt agttgatttc
      721 taaactatcc ttctttttaa aggaatgatt tgatgaagaa aataaaaagc tacaccagta
      781 tttgggcagt tgaaaaggtc atttatgcaa ttaatgactt tcaactgcct tttcctgtga
      841 cttttaacca gatggcttgg tttgttttat ccttgctgtt tgtcatcgta tttgcccatg
      901 tgcctccact atctatgata gagggggcct ttttaaaata cttaggtata ccggtggcag
      961 ttacttggtt catgtcgcaa aaaacgtttg acggtaagaa accattggga tttttacgat
     1021 cttttattag ctatcactta cgatttaagg tcactttcgc aggaaagaaa gtcaaagaac
     1081 agaagaaacg atgggacgaa cccattactc tggtaaggag tgtgaactat gtacccgatt
     1141 aagtatattg aaaataatct tgtctttaat caagagggag aatgttttgc ctactatgag
     1201 ttaatacctt acaattactc ctttttgtca cctgaacaga aatatcaagt ccacgataac
     1261 tttcgtcaat tgattgcgca aaatcgtgaa ggcaagattc atgccttaca aattgccaca
     1321 gaaagtagta ttcgtgccac gcaagaacga tcaaaaaagg aaattaccgg gcgattaaca
     1381 gaagtagcga aacaacgaat tgatttacag acagaggcat tagtatccat gattggcgat
     1441 agtcagattg attatcgctt ttttattggc ttcaaactga ttgcgacaga tgaagaggtc
     1501 aatctaaaga atctcaagaa atctttcttc tccggctttc aagaatttgt ctatggagtg
     1561 aatcatcatt tgatgggcga ttttgtttcc ttatccaatg aagaaattcg ccgatatacc
     1621 aagcttgaaa aactaatgga aagtaaattg gctcgaagat ttaaagtcag acgagtcaca
     1681 ccgagtgatc tgatgtattt gattgaacat atctatggcg aaaagggtac accatttgaa
     1741 gaatatgaat ttcagctacc aaagaaaaag ctgaagtcgg aaactttggt gaaacgttac
     1801 gacttattac gtcccagtcg ttgtttgatt gaagaaaagc cccggtactt atgcatggaa
     1861 catgagaatc atgaatcata tgtagcgtac ttaacaatta atacaattgt gggggaaatg
     1921 gagtttccct cctcagaact tttctattac cagcaacaac aatttacatt cccaattgac
     1981 actagtatga atgtggagat tgtgacgaac aaaaaggcac ttgctaccgt tcgcaataag
     2041 aaaaaggaat taaaagactt ggacaaccat gcctatcaat ctgacaatga aacaaattcc
     2101 aatgtcttag atgcattgga ttccgtagat gaattggaaa ctaccttgga tcagtccaaa
     2161 gaatccatgt acaaactgag ctatgtggtt cgagtaagtg ccgaatcagt agatgaacta
     2221 aagcgccggt gtgatgaagt gctagatttt tatgatgata ccaatgtaaa actagtccgg
     2281 ccttttggcg atatgatggg gctacatgaa gaattcttac cttctagtaa gcgatacatg
     2341 aatgattata tccagtatgt tacgtctgat tttctcgccg gacttggttt tggcgccact
     2401 cagatgttag gggagttgga aggcatttac tttggttata acgtagatac ggggcgcaat
     2461 gtttacctga aaccggcatt ggcctcacaa ggggtcaagg gttcagttac caatgcgcta
     2521 gcagcggcat tcctcggttc actcggtggc ggaaagtcct ttagtaacaa tctcttagtt
     2581 tattacgccg tcctttttgg tggacaagct gtgattgtcg atccaaaagg ggaacggggt
     2641 ggctggaaag aaaccttgcc agaaattgcg gatgaaatca atattctcaa cttaactagt
     2701 aagccaaaaa atcaaggatt acttgatcct tatgtgatta tggagaaaaa gaaggattct
     2761 gaaagtctag caattgatat tctgaccttt ttaacaggaa tttctagtcg agatggggag
     2821 aagtttccag tgttgcgtaa ggccattcgg acggttaccc aaagcaatca acggggatta
     2881 ttacaagtaa ttaatgagct tcgaaaagaa ggctcaccag ttgcggaaaa tatcgcggat
     2941 cacatcgagt cctttaccga ttatgatttt gcccatttgc ttttctcaga tggttcgatt
     3001 acccagtcga ttagtttaga taggcagtta aatatcattc aagtagcgga tttggtttta
     3061 ccagatgcag aaaccacttt tgaagaatat accaccatgg aattgcttag tgtttccatg
     3121 ctaatcgtca tttccacttt tgccttggac tttatccata gtaatcgaga aatcttcaaa
     3181 attgtagact tagatgaggc gtggagtttt cttcaagtag cgcaagggaa aacattatcg
     3241 aataagctcg ttcgtgctgg gcgggctatg aatgccgggg tttactttgt cacgcaaaat
     3301 agtgatgatt tactggatga acgcttgaag aataatatcg ggttgaagtt tgcgtttcgc
     3361 agtaccgata ttcatgaaat caagaaaacc ttggaattct ttggcttgga tcgagaagat
     3421 gaaagcaatc aaaaacgcct acgagatttg gaaaatggcc aatgcttgat gcaggatttg
     3481 tatggtcggg taggcgtggt tcaggtacat ccagtctttg aagaactctt ccatgccttt
     3541 gatacccgtc cacctgttca agagagaatg gagtgagggg atgaaaaaga aactttttcg
     3601 gattgtggga atcgttttta ttagcatact cactctgata gttctattga gtttagttgg
     3661 tacggtagcc gaggcgacag ggctagttga tgatacagtt gaagcaggaa atctatattc
     3721 caaatattca ctgaacaact atcaactaga tttctttgtg gatagctctt gggattggtt
     3781 gccttggaat tggggtgatg gcttagggaa aagcgtgatg tatggtcttt atgccattac
     3841 taatttcatt tggacggtga gtttgtattt gtcgaacgcc acgggttatg tggttcaaga
     3901 ggcttacaaa ttagatttca tttcggatac ggctgaaagt attggaaaga atatccaaac
     3961 attggctggt attactgaaa atggactcca gacctccgga ttttattttg ggtttctatt
     4021 attgatgatt ttagctctgg gggtgtatgt ggcgtatacc ggattattaa aacgagaaac
     4081 cacgaaagca gttcgagccg tgattaattt tgtgatgatt tttctactat cgggttcgtt
     4141 cattgcttat gcgcctacct atatcacaaa aatcaatgac tttagctcag atgttagtga
     4201 agcggccctt acccttggaa ccgagatcgt tgtacccaat tcagaaagcc aaggaaaaga
     4261 tagtgtggat ttgattcggg atagtttgtt ttcgattcaa gtccaacaac cttggttact
     4321 actgcaattt gatgattcca acatagaaga aattggtgaa gaccgggtca acaagattct
     4381 atctgtgagt ccagatgaaa acaaaggcaa agatcgggaa gaagcggtca aggcagagat
     4441 tgaagacaat gacaatgcga atctcagtat taccaagacc atgaaccgtt tagggaccgt
     4501 ggtctttttg gtattgttca atattggcat ttccttcttt gtttttcttc taacagggat
     4561 tatgttgttc tcgcaaattc tcttcattat ctttgcgatg tttctgccaa ttagtttctt
     4621 attgtccatg ttgccgactt atgaaagttt aggaaagaag gcgattattc gtttattcaa
     4681 tacgattatg atgcgagcgg gtgttacttt ggtgattacg actgcattta gcatctccac
     4741 gatgtttttc aatatttcgg caacctatcc atttttcatg gttgcttttc tgcaaattgt
     4801 gacctttgcc ggtatctatt tcaaattggg cgacattatg agtatgttca acctccagag
     4861 taatgatagc cagtcaatgg gaagacgcgt catgcgaaaa ccgcaaatgt taatgaatcg
     4921 aaaattgcgg caactcaatc gaaatgtggg acgagctttg gcttttggtg gtggtgcagc
     4981 agtcggaaat aagttggcaa aggaacaatc aaaatccaaa tttaagccat ccggttcttc
     5041 tctacgaaag aattcacgat taccgaacga tcacgaaata ctatctgact taactaagga
     5101 gaatccagtt tcaaataata agaaacaatc ccgaatgaat ttggctggga gaaaaatcgg
     5161 caaagttttg gatacccaag ctttggtgaa agataagact aaacaagtaa aggatcaggt
     5221 aaggaatacg ccaacgaatt tgaaatacaa tctccataaa ggaatcgaaa agtcgaaaaa
     5281 agcaccagaa gaattcaagc gcggactgtt ccaagaaaaa gcggatcgag tggatttgcg
     5341 agaaaaacaa cgacaacgaa gaaatgcgaa aatggacgaa aaacgcaaga tactgagtga
     5401 agcaacaaat cgtcagggaa aaagaagggc gaatattcca atagataaag cagctcaacc
     5461 tcagaaagat atgatgctga aaaaagaagc accaaagcgg attgtgagag caaatctgaa
     5521 tcccgaaatc aaacgaaaac taactagtca agaaatcatt tcaaaaggga aaagccaatc
     5581 agcaagtaag aaaaattctt tccaacaagt gaaacagagg tccactctgc caaagcagac
     5641 caatcaaaaa gtacaaaaaa gaatgaacca tcgtccaaaa tcaaggtcag gtgagaaaaa
     5701 atgaacttga agaaagtggg tgttatttca ttaacttttc tgaccatctc ttttatgggt
     5761 attttgatgt gtgtgggttt gttgtttggt gaagacagtg agggaaatgg tagttctggc
     5821 acttctcctg gcggaactag tgtctcagaa gaagtattga aacaccgtgc aatggtggaa
     5881 aagtatgcca aagaatcgga tataacagag tatattccaa ttcttttggc gattattcaa
     5941 gtggaatctg gtggcacaat ggaagacgtt atgcaaagtt ctgagtcagc cggattacca
     6001 cctaattcat taagtaccga ggcatccatc aaacaaggct gtctctattt tgcgtctttg
     6061 gttaagcgtt ccaaagaact agggtgtgat caagatagta ttattcaggc ctataactat
     6121 ggtggcgggt atctagatca tgtcgggaaa aacgggaaga agcatagttt tgctttagct
     6181 gaatcttttt caaaggaaaa atcaggtggt caaaaagtcg attaccccaa cccaatcgcg
     6241 attaaggaaa atggtgggtg gcggtataat tatggcaata tgttttactg tttattagtg
     6301 aagcaatacc taactacaac tcagtttgat gacaaaatag tccaagaaat ttttgatgag
     6361 gcatttaagt atgaaggaac ggcctatgtg tttggtggct caagtccaga aacggggttt
     6421 gattgtagtg gcttgaccca atggtgttat gccaaagttg acctgaaact tcctcgggtg
     6481 gctcaggatc aatatgatgc catgactcat attgatctaa aagatgccaa accaggtgat
     6541 ttagttttct ttcattcaac ctatgatgcc ggtacttatg tgacccatgt gggcatttac
     6601 gcaggggaga atcgcatgtt tcatgcagga gatccagtgg ggtggacgaa tctaacggaa
     6661 aactattggc ggcagcatct tatcggagct ggccgataca aataagagaa aagaggaaaa
     6721 agaatgaaga taaaaattga acggaatcaa aaggaaaaga gcccaaaaaa gaaaaaagaa
     6781 cgagttgtat ccgtgggtaa gcatcgaaaa atggtgcttg ccctttggct tttattgtct
     6841 tgtagtcttg cttttggcgt ttataaaaat ttcaccgcca ttgatcaaca tacaactcat
     6901 gaaaaagtgg ttataaaaga gaaggtagtg aatacttctg gcgttgaaag ttttacagag
     6961 gattttgcga aagaatattt ttcatggaaa aataacaaag aagcaattga aaagagaatg
     7021 agtaatctcg aacagtacct tacagaaaac ggtctcgctt taatccaaga tatggttcga
     7081 gcagatattc ccacgagttc cgaagttcaa tctgtaaaaa ttctagatgt tgaaaaacac
     7141 tcggaagaat ttgtcgtttc atttttagtg gagcaacata ttacagaggg aaaaaagacg
     7201 caatcaattt cttctgcata tcgagtgaca atctttgaag atgaaaacag gaatcattta
     7261 gtaactagtt tgccaacaat gattggaaag ccagacaagg caaaatatga agcaaaacaa
     7321 gtagaaaacg attcagaaat tgatgccaaa acaacggaag aaatcaccga ttttttagaa
     7381 acatttttta aactttatcc atcagcttct gaaaaagaat tggagtatta tgttgaaaat
     7441 ggtgcgatgc gaccaatcaa tattgactta aagttttcgg agttagagaa tccagtttat
     7501 ctacaaaacg gaaaaaattt tctagtgagt acaaagataa aataccttga taatgtatca
     7561 aaaaccacta gctactttca gtacaaatta gtattacaaa aaaatggaaa ctggaaaatc
     7621 gttgatgtta aataataatg actcaatcta attttattag aagttataag tagtgtaact
     7681 tatttcaggc agaagtcgcc catcctctat aggtgggtga tgaatgccat tcggtaactc
     7741 gaaaaccgac aattaagaca tagtgccttt ttattttaat ccatgtcata atcagtctat
     7801 ataggaaatg gttgatatac catggaatta gatacaaata atcattcagt ttttcttctt
     7861 ggttaccccc ttattttagt agtgaaacat tgtaaacatg tcattgatga tgtaatgtca
     7921 gcttatgcaa aaactgcctt tgaaagaatt tcagaatcac atcacattac cttagatgaa
     7981 tgaaatcgtg ataaagaata ctttcatatt atgctcaaag cacaacctaa aaccgaatta
     8041 acaaaattca gcaatgccta agctcacgtc tgataaaatg agactttcta agggtcaaaa
     8101 atttcctttg aatacgatta ttgcttagat aaaagtaaaa gccttagaac tacggggata
     8161 gcttggttaa taagagatat cgttgttagt aaagacatag gcttgcaagt atgctctatt
     8221 cccaagaatc tcccccttca agcaccaagg atcgttaaat tcagctaagt ggcaagta
//
LOCUS       DADGKS010000102         8249 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.106, whole genome shotgun sequence.
ACCESSION   DADGKS010000102 DADGKS010000000
VERSION     DADGKS010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8249
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.106"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(204..1652)
                     /gene="cls"
                     /locus_tag="JXV47_002593"
     CDS             complement(204..1652)
                     /gene="cls"
                     /locus_tag="JXV47_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAX1488598.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGEIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHTTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            complement(1804..2697)
                     /locus_tag="JXV47_002594"
     CDS             complement(1804..2697)
                     /locus_tag="JXV47_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1488599.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            complement(2681..3367)
                     /gene="ftsE"
                     /locus_tag="JXV47_002595"
     CDS             complement(2681..3367)
                     /gene="ftsE"
                     /locus_tag="JXV47_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HAX1488600.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            complement(3472..4573)
                     /gene="prfB"
                     /locus_tag="JXV47_002596"
     CDS             complement(join(3472..4509,4511..4573))
                     /gene="prfB"
                     /locus_tag="JXV47_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078989099.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HAX1488601.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRGLFDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            complement(4699..7233)
                     /gene="secA"
                     /locus_tag="JXV47_002597"
     CDS             complement(4699..7233)
                     /gene="secA"
                     /locus_tag="JXV47_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HAX1488602.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            complement(7455..8006)
                     /gene="raiA"
                     /locus_tag="JXV47_002598"
     CDS             complement(7455..8006)
                     /gene="raiA"
                     /locus_tag="JXV47_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HAX1488603.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            complement(8134..>8249)
                     /locus_tag="JXV47_002599"
     CDS             complement(8134..>8249)
                     /locus_tag="JXV47_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HAX1488604.1"
                     /translation="KILIIDDVYTTGQTLFHAADCLQNAQPKIIRTISLAR"
BASE COUNT         2200 a         1816 c         1440 g         2793 t
ORIGIN      
        1 gctatactgg ctttgaaatg tgtctctttt aatagcatat attagcttat ttcttgcttt
       61 ccccaaaaaa caagagatac cccaaagtta atttcgctca tgcgagacgc tttctccatt
      121 tctgacgtac tctcagaaat ggccccgtta aaaaaggaca cgagatctcc atctgttgat
      181 ggttctcatg tcctttttat gttttaaagg agcggcgaaa tcaatcttgc taatccttct
      241 ttcatcttga tgattattcc tcggttttca tacatttctt ttgtgagatg cgtagaaatt
      301 ttcgagtctt caaaaaaagc ttttcttaca cgtgaagcca ttcgttcatc ataaaccagt
      361 gtattgacct caaagtccaa gcgaaatgaa cgaacatcga tatttgctga gccaactgaa
      421 acaatgccac catcgataat catcgtcttt gcatgaataa atccattctc atatgtttcg
      481 atccttgctc catactcgat cagctctgca gcgaaagaat acgttgccca gtaaacgaga
      541 agatgatctg gtttgttagg tatttggata tgaactttta cgcctgaaag aagagccaac
      601 ttcagtgctt catgaatcga tccatccggt atgtaataag gcgtttggat caatatctcc
      661 cgtttggcta acgaaatcat tttcaaataa gtcattttga tttgttcatg ttcggtatct
      721 ggtccgcttg tcacgatttg aacagctata tcaccagtag tgtgaatgga cggaaaaaat
      781 ttgggagaat agcctacttc ttttgtatgc tgagaattcc agtccatcaa aaaacggttt
      841 tgcaaggtat acaccgcttc tccgtaaata cgcaaatgat tgtctcgcca ataaccaaat
      901 ttctttacca atcctagata ttcatttcca acattgaacc cacctgtata tccgatttcc
      961 ccatcaataa ctacgatttt acgatgattg cgataattga tccgaggatt aatatacgga
     1021 acaaatagag gaaagaaaaa tgcgacttct ccgcctgctt ttttcaaatt ctgaaaaaag
     1081 ctggaagaaa cttgtgtgga accccatgca tcaagaagga ctctgacttt tacccctcgt
     1141 cttgccgcct ctgtcaatgc atctcgaact tcttcaccta atgcatcact gcgataaata
     1201 taatactgga agtggatatg gtcttctgcc tgcttgatat cttcaatcag cgcatcgaat
     1261 ttttcacgac catctgtaaa taaagtgatt tcatttttag tcgtatagag cgtactttca
     1321 aataccgtga gcatatagat caattgtttc acatctactt gtccagtagg cggatgagga
     1381 taaagccctc gcatcaatgc ctgtttgtct tcttcaattt ccaggttctt accgattttc
     1441 ccttggatct tcaaatcaaa gattttctct ttggaaatcc ctcttcctaa aaaaatatat
     1501 aaaataaatc ctacaactgg aatgaacatc aaaacgagca gccatgccca tgtttgagca
     1561 gtttcctttc tttctcgaaa aacgatgata aaggaaagca aaatattcat aatcaaaagg
     1621 atcgtaaaaa aattgtcaac gataattttc acggcttcac ctcttcttct accaacttaa
     1681 gaatacccaa gttgtttttt aaagtaaagg gaaaaaagcc gcttccttct attctcctag
     1741 ccaataaaaa aagaaagctg gaacgaaact gtccaacttt ctcattttat ttatattgtg
     1801 gtattagaat ttcaagaaac gtctcataga aatgatcgag ccaagtgaac caatgatcac
     1861 accaatgccg accattaaaa gattgatttt ccaaacgata ttttgtggat gaatcaatga
     1921 ataatgggaa cgtaataatg atggattgat caattggaaa aaccatgcat aaccaaatgt
     1981 gatgatcaaa attggaagaa ttgcaccgat cagaccgatc cagccacctt caaggaaaaa
     2041 cggccagcga atatatccat tttttgcacc gactaaacgc atgatttgaa tttcacgctg
     2101 tctagacaaa atcgtgatcc gaatcgtgtt cgaaatgaga aacatcgcta cgaacagcag
     2161 caatgccgct gcaactaatc cccatgtccg aactgcacca gcgatttgga aaatccgatc
     2221 tgaggaagct ccaccgtaat cagaacgaga aacattcttc aaatctgctg cttcttctgc
     2281 tacttgtttt gtataagaag gatcagtagc acttactaca tacacatcat ataacgggtt
     2341 attgtcacct tcaaacaatt tccaggaatc acccatttcg ttttggattt ttttcaattc
     2401 ctgttctttg cttgaaaatt caactttttt aacatgatct aagtcattca attctttttc
     2461 tagctttttc atctcttcgt cttttgtacc gatatctacg aatacagata catcaacgtt
     2521 tccttctata tcctgagcta atttagttgc attcatgata actgccatga atacaccgac
     2581 taaagtcaac gtgatcgtta ccgcactgac tgaagcaact gtcatccagc cgttacgttt
     2641 caaactcttg atactttcta ataaatggcg gaaaaaggtt ctaatcatcg tatccatatt
     2701 ccccttccgc ttgatctcga ataatgcggc cgttttcgat agcaattact cggtgccgaa
     2761 tcgtatttac gatcgtactg ttatgtgtag ccatcacgac agtagttcct tgggcattga
     2821 tccgatctaa taatttcatg atttcccatg agttttctgg atccagattt cctgtcggtt
     2881 catccgcgat aagtacttta ggcgtattca cgattgcccg agcaatagag acacgttgct
     2941 gttccccacc ggataattcg ctaggaaaga ctcgaacttt gtgtttcaaa ccaacaaggt
     3001 ccagcacttc cattactcgt tttttgatat ctcgaggttt tctgccgata acttgcatag
     3061 cgtacgcaac attttcatat actgtttttc ttggtaataa tttatagtct tggaacacca
     3121 cgccgatttc tctgcgtaga taaggaactt cgcggttttt gattgctatt agatcatgac
     3181 ctgcgacgtt caaagttcct tttgaagctt tttcttctcg atacatcaat ttgatgaatg
     3241 tagatttacc ggctccagac ggaccaacca catagacaaa ctctccttgt tcgatgacaa
     3301 tcgagagatt gcggatagcg gtcgtaccat ttgagtactt cttcattaca tccttcattt
     3361 caatcatggc gttctctcca tatctttttc agtctttagc tattatagca tggcaatgtt
     3421 tcaacatgct tgcaaaatct tacaatttta tttcaattta acaatgggtt cttattgtag
     3481 atgcattttt aaatagccgt caataaataa atcaaggtca ccgtccataa ctgcttggac
     3541 atttcctgtc tctacgtttg tccgatggtc ttttaccata gaatagggat ggaaaacata
     3601 agaacggatc tgtgaacccc agccgatttc tttttgttct cctcgaagtg cagctgcttc
     3661 ttgttctttc ttttccactt ctaattgata aagcttagct tttaacatcc ccatcgcttg
     3721 ctcacggttt ttcaattgtg agcgttgtgc ctgactagct actactgttc ctgtaggcaa
     3781 gtgagtgatc cgtacagcag attctgtttt attgatgtgc tgaccacctg caccacttgc
     3841 tcggtacgta tcgattttca aatcatctgg attgatttct atatcgatcg tttcatcaag
     3901 ctctggcatc acatctaccg aacaaaaaga agtatgacgt cgtttcgctg agtcaaaagg
     3961 cgaaatccgt acaaggcgat gaacaccttt ttctgatttt agataaccaa aagcgttatg
     4021 tcctttaatc agcagggtca cactcttgat ccctgcttca tcacctgctt gataatctag
     4081 tgtttctact tgatagccat gctgctctgc ccaacgtgta tacatacgta aaagcatgct
     4141 gccccagtct tgggactccg ttccgccagc ccctggatgc aattcgacga tcgcattgtt
     4201 tcgatcataa ggtccgtcta acagcataga taattcatac gtcttcattt tttcatctaa
     4261 tgcattgata cgtgtttctg cttcttcttg cattgctgca tcaggttctt cttgcagcat
     4321 ctccaccatc aattcgattt cttctagttc ttcggcaaga gaatggaatt ggtcataggt
     4381 ttctttatta gcgttatttt cgctgatcac tttttgtgcg gcttcgctgt catcccaaaa
     4441 accaggttca gccatttttg cttctgcttc cgcgatgtct tcttccagct gatctaagtc
     4501 aaagagacct cctgaaactt gtgacctttt cctgcatttc tgtcaggaga tttcgaattt
     4561 cggatatttc catgtttttt ccttctttca ctatactttt ttcattatat ctagtctaac
     4621 agaatcagca aataacagaa agaaggtgag acgaattctt aaaaaaagaa tttgtctcac
     4681 caatcctgct gtcagaaatt agtttgcatt ttttccatga cagttcttat attttttccc
     4741 gcttccacaa ggacaaggat catttcttcc gaccttattc acatggattg gctgtttttt
     4801 cgcgctagta ttactatttt ctttggcatc tccgtcttct gagtgagaag ctgttccttg
     4861 agaaacctgt tcacgctgta cgttttgacg gatctcagct ttcataaaga ttcgagtgac
     4921 ttcatactcg atggcgccta ccatatcttc aaacatctta tagccttctg tttgatattc
     4981 gactaatgga ttgttctgtc cataagcacg taagccgatt gactgacgta attgatccat
     5041 tgcatcaata tggtctgtcc atttagagtc cacaacacgc aagatcacga ctttttcaaa
     5101 ttccaacagt tgctctggac catttagttg agccgctttg gtattaaata cttcttgtgc
     5161 tcgttcgttt agatactctt tgatctcctg agctgttttt ccttcgatat ctgcaagagt
     5221 aatgctatct tcatggacaa gagtactgcc ggcaaaatcg atgatacttt ccaaattcca
     5281 attttctttc tctaattgtg tatgcgcatc tactacacga ctgattgtcc gtttgaccat
     5341 gttcattagt ggcttggata agcttttttc ttccatgatt acttcttgtc gctgtttata
     5401 gattacttca cgttgttcac gcatcacatc atcgtattgt aagacgtttt tacgtgtgtc
     5461 atagttattt ccttctacac gtttttgtgc agattctact tgtttcgtca gcatcttgct
     5521 ttggataaca gcatcttcct caccgatctt catccgatct aagaaagctt tgattcgttc
     5581 tgaaccgaat cgtttcatca aatcatcttc caatgacaag tagaactgtg acataccagg
     5641 gtctccttga cgtcctgcac gtcctcgaag ctggttatcg atacgacgag attcatgtcg
     5701 ttctgtcccg ataactgcta gaccaccaag ttctcttacc ccaagtccta acttgatatc
     5761 tgttccccga ccagccatgt tggtagcaat cgtcacagca cctttttgac cagcattcat
     5821 gatgatctct gcttctttaa agtgattttt cgcattcagc acttcatgag gaatacgttc
     5881 ttgattcagc atatctgata ataactcaga tgtttcaacc gcaacagttc cgactaacac
     5941 aggttgacct ttgcggtagc gatctttgat atcttgcacg acagcgtgga acttgctttg
     6001 taatgttggg taaagcaaat ctggacgatc atcacggata accggacgat ttgtcggaat
     6061 ctggtatact tggatgttat aaatttctct gaattcttct tcttctgttt tagctgtacc
     6121 agtcattccc gcaagtttct tgtacatacg gaaatagttc tggaaagtga tcgtcgccat
     6181 ggttttcgtt tcgtcttcga tctctacgcc ttctttagct tcgattgctt ggtgaagtcc
     6241 atctgaataa cggcgtccat ccatgatccg accagtgaac tggtcaacaa tcagtacttt
     6301 tccgtcttgg acaacataat cgatatctaa aagcatgata tagttggctc tcaatgcttg
     6361 atccaagtga tgggtcaatg cagtattttc aatgtcgtat aagttatcca aaccgaatgt
     6421 ttcttctgct ttttcgatcc ctgcttcggt taaactgatt gtttttgatt gtacatcgat
     6481 tttataatct tcttcttctt tcaaacgttt cacgaagttg tctgctcttg tatataaagc
     6541 tgtggatttt tctgcttgcc ctgaaatgat cagcggcgtt ctcgcttcat caatcaagat
     6601 tgagtcaact tcatcgacaa tggcataatt cagcggacgt tgtaccattt gatggcggta
     6661 aacgaccata ttgtctctca agtagtcaaa tcctaattca ttattcgtac tataagtgat
     6721 atcacaatta taagcctcgc gtttttcatc cgaagatttt gagttgatat tcaaccccac
     6781 tgttaatcct aagaaattat aaagttcgcc catttccgtc gagtcacggg ttgctaaata
     6841 ttcattgacg gtaactacgt gtaccccttc gccagtcaga gcatttagat atactggcat
     6901 cgttgcggtc aaggttttac cttcaccagt acgcatttca gggatatttc catcgtgaag
     6961 cacgattcca cccatcaatt gtacgtggta tggatataaa cctaatacac gttttgctgc
     7021 ttctcggacg actgcaaaag cttccggaag taattgatct aatgtttctc ctttttggta
     7081 tctgcccttg aattcagcag tttttgcctg taattgttca tcagttaatg ctgccatttg
     7141 gtcagcgtat gcttcaactt tttttgcaat gctatctaaa cgttttagtt ctttcttatc
     7201 gttttcgata agtgaacgaa tcaaattggc catgcgttgt gtaatctcct tttccttctg
     7261 tgtattatcc agactatgta gactttactt ttcattttat cattagttat agataattga
     7321 aatatcttaa gcgtattaaa gtaagaactt cataatttat tcatatttca tctaaaagag
     7381 gaggaaactc aaaaaaactt gcggcagctg tcagtagctg ctgcaagttt tcgttgttat
     7441 ttaagtaagg ctgatcagtc tgtttcaatc agtccgtatt ttccatcttt acggcggtaa
     7501 acgatacttg taccatttgt ttctgcatct tcaaaaataa agaagttatg tcccagcatg
     7561 ttcatttgta agactgcttc ttcactatcc attggtttca atgaaaggcg tttcgtacgt
     7621 acgatatcta attcagaatc attttcgttt tcgtcctctt cattgaataa agcagcagca
     7681 tctgcagtat tcatgcccgt ttcacgggat ttacgattaa tttttgtttt gaatttgcgg
     7741 atttggcgtt ccaatttgtc aacaaccaaa tcgatacttg cgtataaatc tggagaagtt
     7801 tcttcggcac gtaatacaag ataaggtaat gggatcgtta cttccacttt tgctgttttt
     7861 tctgtataaa cttttaagtt cacatgcgcc gttgcatcgg gtgcgtcact gaaatagcgt
     7921 tctagtttgc ctactttttt ctcaacgtag tcgcgaatcg cttcagttac ttcgatattt
     7981 tcgccgcgta cattatatct aaacataaaa attacccctt tcgtctacca caatcaagaa
     8041 ggagaaggac cactctttcc ctcttcttaa ttctattata tcgaactcta ggttatttgc
     8101 aaattaaatc gctatcaaat ttccacatct gattcatctt gccaaagaaa tggttcggat
     8161 gattttcggc tgtgcgttct gcaagcaatc tgctgcatga aaaagcgtct gtcctgttgt
     8221 atagacatcg tcaataatca atatttttt
//
LOCUS       DADGKS010000103         8243 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.107, whole genome shotgun sequence.
ACCESSION   DADGKS010000103 DADGKS010000000
VERSION     DADGKS010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8243
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.107"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..197)
                     /locus_tag="JXV47_002600"
     CDS             complement(<1..197)
                     /locus_tag="JXV47_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488605.1"
                     /translation="MRELTLSSKELEKKTALLNEIFSADCIIQSLKESSFSKLTDQEK
                     ISYMLSLDNLGTKYDESASSD"
     gene            complement(248..1876)
                     /locus_tag="JXV47_002601"
     CDS             complement(248..1876)
                     /locus_tag="JXV47_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488606.1"
                     /translation="MPEIEGIFSPKIGKKQLDFSSFPSVNRDYNLGDEVQILNIDFKE
                     LDFAVAVSNKPKALERVKKIYQENDQNIKNMIKKYRRDNSKVEDVLFNGTAKHDLNVY
                     MALGVALYCNSINQTDILVNIVRNSYQKILKISSETNPYYAMKYLGDNLLNDKKLMHN
                     TEELLSNLAAINFLFKTGSEDYFIDNVLKGAYGTAFYPLYNMKQHKAEQKDNKLEIKK
                     MKELLGIGFVKPNSKVTIASLATTNNDGKIVNGFDDSDIDILSKSYFSLYGDFADLMG
                     IDSYLVNNFEIKGSELNDIVYFVLISLYAIDQNTEYRQIDYLLVFYSLLYQFVLTRLF
                     KNAKEELILNSDYEIAKQIASIRKENKSEVIKLRKELSIASKENGRLESLVKSAKKEE
                     ELLKQEIKELKGIRKELEQLRFENKVLKQLQEQEHRQSLNGKTEEPSLSEMIAYLKHK
                     NILLVGGHVNFQNKLTELLPNIKMFDVSENNGKILKNLNTCDAIFLYTDYLNHGLYYR
                     VMSEISNKDKIFYLDNHVNMNLTIKRIYDLLSLI"
     gene            complement(1896..2063)
                     /locus_tag="JXV47_002602"
     CDS             complement(1896..2063)
                     /locus_tag="JXV47_002602"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488607.1"
                     /translation="MVNEVETLLASFFENGHVNDEWRKEEPKRVNAYIARLKRFIDKY
                     KENSDKFSKDK"
     gene            complement(2100..2789)
                     /locus_tag="JXV47_002603"
     CDS             complement(2100..2789)
                     /locus_tag="JXV47_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein"
                     /protein_id="HAX1488608.1"
                     /translation="MRTHYIYLEDKIVDEIPAKSREQARKLFIEKYKEINGDSEVPKV
                     VVTVRKRQTKKRSTFHVSPDIYNLIERHRSEDNISISQYIATVIDELISGKYDYAFDF
                     EGEKDYKSVAVFQSDFEKLKNYAGRRNVNFARLLEEFYSEELGVGNEYKRETYAKLSH
                     KLSQALKEVTEVKAELDAKLEEVKKYQTERKNNMKNQVEFDEQKEFEKARKRYNKIMN
                     ELSYEHLTVHE"
     gene            complement(3044..3364)
                     /locus_tag="JXV47_002604"
     CDS             complement(3044..3364)
                     /locus_tag="JXV47_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488609.1"
                     /translation="MKKKIVEGNVGVIILKDSTDYAKSMALKDEKVARMDKDLVEFLM
                     DDTERLKGDQFLSLMKDKGLNTYGLFDYKKLAIEWVKEGEIFFIEEWEGTENLVLHQY
                     LLKA"
     gene            complement(3397..4515)
                     /locus_tag="JXV47_002605"
     CDS             complement(3397..4515)
                     /locus_tag="JXV47_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488610.1"
                     /translation="MGNNSIYTPEMQNKIKRLVGLGWMTRGKLDSFSTIKYLLMDIYR
                     QNKQTGIHFLGYDKPEDAPFFVPSSAYRASTSGSMYNLDLFEEGAKMIEYDFNEAYSR
                     IMRNYPLPSNTYLKAKYNTDQAILRAINRPKVRPYENLKTYMFFLVNFEGTAKEGTYA
                     NPKSQSMFADYGENPKTANEPIWLSEIELTLILDYYDIKEMEVLDSHTFLTKKGLLKE
                     YFERIEPLKTDPDTLKLYKNLRTKVFGAIGQKSLREGETSTFDKYSMYNRAYSSMVAG
                     VFRDRMVRYEQKYVHSAYGLLKIRTDGLYFRSEVPEFEELYKLGVVKKKVHTISKEEV
                     EKALEFKNKGFENKGSFGKSKDEVKGVVIDDDFEFDFD"
     gene            complement(4544..5338)
                     /locus_tag="JXV47_002606"
     CDS             complement(4544..5338)
                     /locus_tag="JXV47_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488611.1"
                     /translation="MVAKKNTLKEASEKYQDMKRRGLIPKDKKGIWREFVKEVSSDRS
                     GGDFVGRYTAKGYSRRLRITVEYGTNESATELKQRYLDTRREASKKYDDFKSRGLIPK
                     KKKGIWREFFKEEDSNRNKGDFIGRYTAKGYTKNLGIKVEYGTGESSWELRNRYLNTL
                     LEKYKAELLELFDVNDFIEMAEKYGHEEGFMINDIMVIDNFTDLLALAKKARDLRETQ
                     MYLFRNKNGRNRRTESSEIEDYYDAFTHDLGAFVDEISGVMNKYRV"
     gene            complement(5348..6223)
                     /locus_tag="JXV47_002607"
     CDS             complement(5348..6223)
                     /locus_tag="JXV47_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488612.1"
                     /translation="MTTNKRWSELVQNTVKKVMPDGYHFNYIQCSQTTESIYFSILNE
                     NRLYYFRVSSHHRKKREDNVTTFLSGKYNGFKELSEAIGEYLKSNRFVRISDKHILIL
                     LLYLNNSFKLFWRDDTFYYIENGMDIYSGINGILKHYIKALLRYGVLYQEDLSNQIKI
                     SNSGKSLLAKYKKLLSPIYKGIDMEAVNSETLFNLVVDEKFANEFFKSKKIERLNNLF
                     PENAIKAYVDNNKSRLYNWFIPKRLRGKIKIGDQVKVINLNHTKIVTVTELYIAEKED
                     ITKMKPVIKILDNKE"
     gene            complement(6440..6697)
                     /locus_tag="JXV47_002608"
     CDS             complement(6440..6697)
                     /locus_tag="JXV47_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488613.1"
                     /translation="MINEDFRSENKMIDISLIEKLLFSNKYTAKELATRWQISESAIK
                     AYRQNKGSVGWRDWKGISIGKAEDIMKREGFQADNDSKKVE"
     gene            complement(6700..6924)
                     /locus_tag="JXV47_002609"
     CDS             complement(6700..6924)
                     /locus_tag="JXV47_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488614.1"
                     /translation="MNQRRRKRLEEISERLSELKDELEVIQEEEYKENIPKNLQGSER
                     YEKAEESVDQLEEAVDGLSDILELIEDIAS"
     gene            complement(7097..8140)
                     /locus_tag="JXV47_002610"
     CDS             complement(7097..8140)
                     /locus_tag="JXV47_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyhydrolase"
                     /protein_id="HAX1488615.1"
                     /translation="MKKFLVGILFTMGLVLLSPSVSAESSISMYRMYNPNSGEHLYTR
                     SVGERDNLKRYGWHYEGVAWQAPTSGTPVYRLYNRYNGEHFYTVDAGERDKISHTGWT
                     YEGVAFYSYNGANRVPVTRLYNKYVNWHHYTLDQNEKNVISKQGWKIEGTGWYAMPNS
                     VPNPTPAPSTEKVLNVPVVWQGNTMLCEGASLLEGLHYKGVATNQSLTSFVNYMPKAN
                     DNNPYHGYSGEWRHNVNGTYQGMMADPVVKWAKNVGGNAVNITGSGTNGIKNEIRNGN
                     PVVTWITYNYATPEFKQMPWGRAVWNGHVVLVDGFRNGAYHVVDPVFGAKWINASTYE
                     RAFNVTGMAVAVR"
BASE COUNT         2321 a         1686 c         1030 g         3206 t
ORIGIN      
        1 ttatcgctac ttgctgattc atcatattta gttcctagat tatctaaact tagcatataa
       61 gaaatttttt cctgatctgt tagttttgaa aatgaacttt cttttaaact ttggattata
      121 caatcagcac taaatatttc gtttaataaa gcagttttct tttctaattc cttagaagat
      181 aaagttagtt ctctcatagt gacttaccta ctttccaaat tttgtgtcct atttatcact
      241 tctctcttta tataagtgat aaaagatcgt aaatacgttt aattgttaag ttcatattca
      301 catgattatc caaataaaat atcttatctt tattagaaat ttcactcata acacgataat
      361 atagaccatg attcaagtaa tctgtatata gaaaaatcgc atcacacgta ttcaaatttt
      421 taagtatctt tccattattt tcgcttacat caaacatttt aatatttggt aatagttcag
      481 ttaatttatt ttgaaaattt acatgtcctc ccactaaaag aatgttttta tgttttagat
      541 aagctatcat ttcagacagt gaaggctctt cagttttacc atttaatgat tgtctatgtt
      601 cttgctcctg caattgcttt aatactttat tttcaaacct cagctgttca agttcttttc
      661 tgattccttt taattcttta atctcttgct tcaaaagttc ctcttctttt tttgccgatt
      721 tgactaaaga ttctaaccga ccgttttctt tactcgcaat acttaattct tttcttaatt
      781 tgattacttc agatttgttt tcttttctaa tacttgcaat ttgttttgct atttcataat
      841 cagaattcag gatcaattct tccttagcat ttttaaacaa ccgagttaaa acgaactgat
      901 ataacaaact ataaaaaact agcaaatagt caatttgtcg gtactcggta ttctgatcaa
      961 ttgcatatag agagattaaa acgaaataca caatatcatt cagctcgcta cccttgatct
     1021 caaaattatt gactaagtaa ctatcaatac ccatcaaatc tgcaaaatct ccatacaaag
     1081 aaaaatatga ttttgacaat atatctatat ctgaatcgtc aaacccattt actattttcc
     1141 catcattgtt agtagttgct aacgaagcaa tagtgacttt tgaattgggt tttacaaatc
     1201 ctatacctaa tagttctttc atctttttaa tttcaagttt gttatccttt tgttcggctt
     1261 tatgctgttt catattgtaa agcggataaa atgctgttcc gtaagcacct tttagtacgt
     1321 tatctataaa ataatcttca gaacctgttt tgaatagaaa gttaatcgca gccaaattag
     1381 ataacagctc ttcagtgttg tgcatcaatt ttttatcatt taataaatta tccccaagat
     1441 atttcattgc ataataaggg tttgtttcgc tacttatttt taatattttt tgatagctat
     1501 tcctcacgat attaaccaaa atatctgtct gattaattga attacagtac aaagccactc
     1561 ctaatgccat ataaacattc aaatcatgtt ttgccgtacc gttgaataaa acgtcttcaa
     1621 cttttgaatt atctcgtcta tactttttga tcatattttt gatattttga tcattctctt
     1681 ggtatatttt tttcactcgt tccaatgcct tgggtttgtt ggaaacagca acagcgaagt
     1741 ctagttcttt gaaatcaata tttagtatct gtacctcatc acctagatta taatctctat
     1801 ttacgctcgg aaaactgctg aaatctaact gttttttacc tatttttggc gaaaatattc
     1861 cttcgatttc tggcaaatgt aatcacactc tctccttatt tatctttaga aaatttgtca
     1921 ctattctcct tatatttatc aataaacctt tttaatcgag caatataagc gttaaccctt
     1981 ttaggttctt cttttcgcca ttcatcgttt acgtgaccat tttcaaagaa agaagctaaa
     2041 agagtttcca cttcattaac catatctgcg atcgtatatt tttctgtacc ctcactcaat
     2101 tattcatgaa ctgttaagtg ttcatagcta agttcattca taattttgtt atagcgtttt
     2161 cttgcttttt caaattcttt ctgttcgtca aattccactt gattcttcat gttgttcttc
     2221 ctctctgttt gatatttttt cacttcttca agtttagcat ctagttccgc tttaacttct
     2281 gtcacttctt taagcgcttg ggataactta tgagacaatt tcgcataagt ttctctcttg
     2341 tattcatttc ctactcccaa ctcttcggag tagaactctt ctagtagtct tgcaaaatta
     2401 acatttctcc tgccagcata gttttttagc ttctcaaaat cagattgaaa gacagcaaca
     2461 cttttgtaat ccttttcacc ctcaaaatca aaagcatagt catactttcc tgaaatcaat
     2521 tcatcaataa ctgtagcaat atattgagag atagaaatat tatcttcact tctatgtcgc
     2581 tctataagat tatatatatc agggctgaca tgaaacgtac ttctcttttt tgtttgcctt
     2641 tttctaactg ttacgaccac ttttggaact tcactatctc cattgatctc tttgtatttt
     2701 tcaataaata attttctagc ttgttctcga ctttttgccg gaatttcatc tacaatttta
     2761 tcttctaaat aaatatagtg tgttctcata cattcgtcct ctatcttctt tactctcaat
     2821 cttcatgatc ttagttctta ccttgtttac tcttaaacat tgcaaaaaaa tctagtcaaa
     2881 atcaaacttg aaatcatcgt ctatcacaac acccttaact tcatctttag atttcccaaa
     2941 ggaaccctta ttttcaaatc ctttattttt gaatgatgat ggttatggaa aacttccttt
     3001 gaaattctga caagcataac tagtcagaac tgttttactt agattaagct ttcaaaagat
     3061 actgatgaag aactaagttc tcagtacctt cccattcttc aataaaaaat atttctcctt
     3121 cttttaccca ctctatagct aatttcttat aatcaaataa accatatgtg tttaagcctt
     3181 tgtctttcat taaactcaaa aactgatccc cttttaatct ttctgtatca tccatcagaa
     3241 attcaactaa atctttatcc atgcgtgcaa ctttttcgtc ttttagtgcc attgatttag
     3301 catagtcagt tgaatctttt agaataataa cacctacatt tccttccaca attttcttct
     3361 tcatatttac ctcctaccat cttttccaaa gagtatttag tcaaaatcaa actcgaaatc
     3421 atcgtctatc acaacaccct taacttcatc tttagatttc ccaaaggagc ccttattttc
     3481 aaatcctttg tttttaaatt ctaaagcttt ttcgacttct tctttggata ttgtatgaac
     3541 ttttttctta actactccaa gtttatacag ctcttcaaac tctggtactt cggatctgaa
     3601 atacaatcca tcagtacgaa tttttaatag cccatatgcg ctatgaacgt atttctgttc
     3661 atatctaacc atacgatctc taaatacgcc tgctaccatg gaggaatacg ctcgattata
     3721 catactgtat ttatcgaagg tgcttgtttc tccttctctt aatgattttt gtccgatagc
     3781 accaaatact ttcgttctaa gatttttata aagcttcaac gtatcaggat cagtttttaa
     3841 tggctcgatt ctttcaaaat attctttgag taatcctttt ttcgtcaaaa atgtgtggct
     3901 atctaggact tccatctctt taatatcata ataatcaagg ataagtgtta gctcaatctc
     3961 cgataaccaa ataggctcat tagctgtttt gggattttcg ccataatccg caaacatcga
     4021 ctgtgatttt ggattagcat atgttccttc tttggctgtt ccttcaaaat taaccaaaaa
     4081 gaacatatac gtttttaaat tttcatacgg tcttactttt ggtctattta tcgctctcaa
     4141 aatagcttga tctgtattat attttgcttt caaataagtg tttgacggca aaggataatt
     4201 tctcatgatc ctcgaatagg cttcgttgaa atcatattcg atcatctttg ctccttcctc
     4261 aaacaaatcc aagttataca tgctaccgga ggtactggct ctataggctg aacttggaac
     4321 aaagaaaggt gcatcttccg gcttatcata gcccaaaaaa tgtattcctg tttgcttgtt
     4381 ctgacggtaa atgtccatca aaagatattt gatcgtacta aaagaatcta attttcctct
     4441 tgtcatccac cctaatccga caagtctttt aattttattc tgcatttcag gtgtgtatat
     4501 gctattgttt cccatttatc tgctcatctc cggctttttt attctagacc ctatatttgt
     4561 tcattacacc acttatctcg tctacaaagg ctcccagatc gtgtgtaaag gcatcatagt
     4621 aatcttcaat ctcactcgat tcagttctcc ggtttcttcc gtttttattt ctgaatagat
     4681 acatctgcgt ttctcttaaa tcccttgctt ttttcgcaag tgctaataaa tccgtaaaat
     4741 tatcaataac cataatgtca ttgatcataa aaccttcttc atgaccatac ttttcagcca
     4801 tctcgataaa atcattaaca tcgaacaact ccaataattc tgctttatat ttctctaaca
     4861 atgtatttaa atagcgattt ctcaattccc atgaactttc accagttccg tattcaacct
     4921 tgatccctaa attcttagtg tagccttttg ctgtgtatcg tccaatgaag tctcccttat
     4981 tccgattgct atcttcttct ttgaaaaact cacgccaaat cccctttttc ttcttaggaa
     5041 ttagacctct gctcttgaaa tcatcatatt tttttgaagc ttctcttcgt gtatctaagt
     5101 acctttgctt cagctctgta gctgattcat tcgttccata ttcaacagtg atccttaagc
     5161 gcctgctata accttttgct gtatatcgtc caacaaagtc accgccactt cgatcactac
     5221 tgacttcctt aacaaattct ctccatatac cttttttgtc ctttggtatt aatcctcgtc
     5281 ttttcatatc ttgatatttt tcagaagctt cttttagagt attctttttt gctaccatat
     5341 attccactca ctctttgtta tctagtattt taataactgg tttcattttt gtaatatctt
     5401 ctttttcagc tatatacaac tccgttacgg taacgatctt agtatgattt agattaatta
     5461 ctttcacttg atcgccaatt ttgatttttc ctcgcaaccg tttgggaata aaccagttgt
     5521 ataatcgtga tttattatta tctacataag cttttattgc attttcagga aacaggttat
     5581 ttagtctttc aattttttta cttttaaaaa attcattcgc aaacttttca tcaacaacta
     5641 aattaaataa agtttcagaa tttacagctt ccatatctat tcctttgtag ataggagaaa
     5701 gcaatttttt atattttgcc agtaatgact ttccagaatt actaatctta atttggttac
     5761 ttaaatcttc ttgataaaga accccatatc gaagtaacgc cttaatataa tgttttaata
     5821 tgccgttgat accagaataa atatccatgc cgttctcaat atagtagaaa gtgtcgtctc
     5881 tccaaaacaa tttgaagcta ttattcaaat aaagtaacaa gatcaatata tgtttgtcag
     5941 aaattctgac aaatctatta ctttttagat actcaccaat ggcttcactt aactctttga
     6001 agccattgta ttttcccgat aaaaatgtcg taacattatc ttctctcttt ttcctatggt
     6061 gtgaacttac cctgaaataa tagagtctat tctcatttaa tattgaaaaa taaatacttt
     6121 cagttgtttg tgagcattgt atatagttga aatgatatcc atctggcatg acttttttaa
     6181 ctgtattttg tactagctct gaccaccttt tgttagtagt catatatttt tttccattaa
     6241 accaaacata aatatctttt ttaaaaattt tgttcccccc ctattgcgtt ttctttgaca
     6301 ttaaagccct ttgttttcat cacattcgta tagccctagc cactcataac ctgatgcttt
     6361 tgcgaagttt atttaaaagt gttttccttt gtaatctacc tttcccctcg tcctggtact
     6421 tttcttggcg actattaaac tattcaactt ttttagaatc attgtcagct tgaaatcctt
     6481 cacgtttcat tatgtcttct gcttttccaa tgctgattcc tttccaatca cgccatccta
     6541 cgcttccctt attttgacga taggctttaa tagctgattc ggatatttgc catcttgtag
     6601 ccaactcttt ggctgtgtac ttatttgaaa aaagtagctt ctctatcagt gaaatatcaa
     6661 tcattttatt ctcactcctg aaatcttcat taatcatctc tagctagcta tatcttcaat
     6721 caattctaat atgtcggata aaccatcaac agcttcttca agttgatcaa cggattcttc
     6781 tgctttttca tatctttctg atccctgtag atttttaggt atattttctt tgtactcttc
     6841 ttcttgaatt acttctaact catcctttag ctcggaaagt cgctcgctta tttcttctaa
     6901 cctttttctt cttctttggt tcatcaaaat cacctcttcg cataatctct acgattttaa
     6961 tataccactt ttgtgtacta cattcaatat tttttgttat agattcgtat tacaaaaatt
     7021 tcctctaaaa aaataagagc ctatttacca tttcagtaat taagctctta tttcatttag
     7081 ttgataattc tatcaattaa cgtacagcaa ccgccattcc agtcacatta aatgctctct
     7141 catacgtgct tgcattgatc cattttgcgc caaatacagg gtcaacaaca tggtatgcac
     7201 catttctgaa gccatccacg agaactacat gtccattcca tactgcacga ccccaaggca
     7261 tttgtttgaa ctctggcgta gcatagttat aagtaatcca agttacaacc ggattaccat
     7321 tgcgaatttc attcttgatt ccattcgttc ctgaaccagt gatattgacg gcattaccgc
     7381 caacgttttt tgcccattta actactgggt cagccatcat gccttgatac gttccattaa
     7441 cgttatgacg ccactctcct gagtaaccat gataaggatt attgtcatta gcttttggca
     7501 tatagtttac aaaactggtt aagctttgat ttgtggctac acctttgtag tgtaaacctt
     7561 ctaataaaga agctccttcg cataacattg tatttccttg ccatacaaca ggaacgttca
     7621 acactttttc agtgcttgga gcaggtgtag gatttggtac gctgtttggc attgcatacc
     7681 agcctgtacc ttcaatcttc caaccttgtt tactaattac gttcttttca ttttgatcta
     7741 acgtgtagtg atgccaattc acgtatttgt tatataaacg tgttacagga actctatttg
     7801 ctccgttgta ggaatagaac gcaacacctt cgtacgtcca tcctgtgtgt gaaatcttat
     7861 ctctttctcc ggcatcaact gtgtaaaaat gttcaccgtt ataccgatta tacaaacgat
     7921 aaacaggagt accacttgtt ggagcttgcc atgcgacacc ttcgtaatgc catccataac
     7981 gtttcagatt gtctctttct ccaacgcttc tagtgtatag atgctctccg ctattgggat
     8041 tatacatacg atacatggaa atagagcttt ctgctgaaac tgaaggtgat aataatacta
     8101 gccccattgt gaatagaatt cctactaaaa attttttcat ttgattttac cccttttcat
     8161 tttttattgt cattattgca tgaaaattat tcgtaagatt gccaattaca taaacgattg
     8221 ttttaagatc ataatcgttg ttg
//
LOCUS       DADGKS010000104         8075 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.108, whole genome shotgun sequence.
ACCESSION   DADGKS010000104 DADGKS010000000
VERSION     DADGKS010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8075
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.108"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            4..1458
                     /locus_tag="JXV47_002611"
     CDS             4..1458
                     /locus_tag="JXV47_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010825391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-acylating methylmalonate-semialdehyde
                     dehydrogenase"
                     /protein_id="HAX1488616.1"
                     /translation="MTRFLRNYIDGRWVASRSTEFEEVMNPATEEALANVPLSSKAET
                     AEAVKAADAAFQTWKKVPVPVRGRYLFKLHQLLTDHKSELARLITLENGKSLSESLGE
                     VQRGIENVEHAAGITNLMMGDSLSTAATDIEITNYRYPIGVIGGITPFNFPMMVPFWI
                     FPMALAAGNTVVLKPSEKTPLLMEKIVELVEKAGFPSGVFNVVYGAHDVVNTLLQDPL
                     VKGISFVGSKNVGEYVYREGTKNLKRVQALTGAKNHVVVLKDANIDRAVKDLIGGAFG
                     SAGERCMAASVIVLEEEIADQFVEKFKAAAKAIKIGNGLDEGVFLGPVIRKDAQQRTF
                     DYIQKGVDEGAKLVLDGRENIPEKGYFVGPTIFDNVTMDMKIWQDEIFAPVASIVRVK
                     DLMAAVELTNESEFANGSCLYTNNASAIRYFRENVDAGMLGVNLGVPAPMAWFAFSGW
                     KHSFFGDLHANGKDSVEFYTHRKVVTARYAQSEI"
     gene            1534..2694
                     /locus_tag="JXV47_002612"
     CDS             1534..2694
                     /locus_tag="JXV47_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HAX1488617.1"
                     /translation="MNIQLKMPANLRIGGGTIQFLMEESEQLGNKPLIISDTVMEQTG
                     HLQKIKELLGKTDDQLAEYTDIQAEPTQENVYDALKLFQKHQCDHIIAFGGGSCLDTA
                     KVVAVLAANQLSLEAIHARNFDQLQAGIPLIAVSTTAGTGSEVTDVAVITNTKTAVKM
                     MMKDLVFMPQISIVDSDFTKTVPPKVTAATGVDALCHALESYVSVKANEVTQLFSLEA
                     MKKILNTLSQAYENSDDTEAREQMSLASTEAGIAFSNASVTLIHGMSRPVGALFHIPH
                     GISNAMLLPVFFEFSKDAIQTELATIARFIYPAAEDLSLEEAADYLIKKIQELCEQLS
                     IPTIRDYGIDQQAFMAALDKMAADALTSGSPQNNKKVPSHSQIKELYVQAYG"
     gene            2807..3814
                     /locus_tag="JXV47_002613"
     CDS             2807..3814
                     /locus_tag="JXV47_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAX1488618.1"
                     /translation="MRVKVGVIGTGAIGIEHIDRINQKTQGAYVTAVSDINVKAAKEV
                     AKRVDAKFFETGEALIASEDVDVVVVTSWDPTHEQYVLEAIKHGKYVFCEKPLAMDAA
                     GCRRIVDAEVAYGKKLVQVGFMRRYDRGYIELKEAIESKQYGEALMMHCAHRNPSADE
                     NYTTPMAISNTAIHEIDVLRWLLNEDYESVQMILPKKTSNSHADLHDPQLLIFQTKSG
                     VTIDLEIFVNCRFGYDIKCDVVFETAEVGMTDPAYTRIKSEEKNYTPVSPDWQTRFLD
                     AYDYEFKLWIDSIKNDAVVGPTAWDGYVAAITMMACHESRETKTKVMIQMDERPALYN
                     E"
     gene            3838..4863
                     /gene="iolG"
                     /locus_tag="JXV47_002614"
     CDS             3838..4863
                     /gene="iolG"
                     /locus_tag="JXV47_002614"
                     /EC_number="1.1.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol 2-dehydrogenase"
                     /protein_id="HAX1488619.1"
                     /translation="MNNIRVGIVGLGRLGKVHAQNLATGVSCCELTAACSLVETELAF
                     AQKKLGVKHTFSSYEEMVKSSVIDAVFIVSPSGFHCDQVRLAMENGKHVFTEKPLGLE
                     VEDIKKTQKVIEEHPEQVFMLGFMRRYDESYQYAKKMVEDGEIGEITLIRCYGIDPSE
                     GLESFVKFAMNNDSGGLFLDMAIHDIDLVRWFTGQEVDQVWAIGKNAAYPELDQAGEL
                     ETGAAMMSLSDKTIALLVAGRNAAHGYHVETEIMGTKGMLRVAQAPEKNLVTIMNDQG
                     IIRPCSQNFPERFREAFIREAQEFVSCIQEKRQPAVNAEDGLQSTKIALACQESFDTK
                     SLVQLKK"
     gene            4880..5770
                     /gene="iolE"
                     /locus_tag="JXV47_002615"
     CDS             4880..5770
                     /gene="iolE"
                     /locus_tag="JXV47_002615"
                     /EC_number="4.2.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015076872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="myo-inosose-2 dehydratase"
                     /protein_id="HAX1488620.1"
                     /translation="MTKQIQLAIAPIAWTNDDMPELGSENTFEQCISEMALAGFTGTE
                     IGNKYPKDPEVLEQYLNIRGLKVASAWFSAFLTTKPFEETAEAFKAHRDFLHAMGAKV
                     IVVAEQGHSIQGIMTAPVFDDKPVFTDEEWKKLAEGLEKLGDLAHEKDMEIVYHHHMG
                     TGVQTTEEIDRLMEMTDPDKVKLLFDTGHLVFSGENPIAVYNRHQDRIKHIHFKDIRQ
                     ETAEEVEKEKDSFLNGVKKGVFTVPGDGMIDFTPIWTAIHASDYEGWIVVEAEQDPAK
                     ANPFEYAVKARSYIREVTGL"
     gene            5793..7388
                     /locus_tag="JXV47_002616"
     CDS             5793..7388
                     /locus_tag="JXV47_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="solute:sodium symporter family transporter"
                     /protein_id="HAX1488621.1"
                     /translation="MNLFSIISFLVIVICVWLFAYSRSRSVDTSGSEGFFMGGRSLTA
                     LPIAGTIIMTNLSTEQIVGQNGQSYHAGMEVMAWEVTATIAIVALAVIFLPKYFKYGI
                     NTISDFIEIRYDTVTKRIISILFIVTYMTSFLPVVLYSGSLVFNKIFHIDELLGVQPI
                     VAIIIVAMAIGIVGILYLLIGGLSLSANSDSIYGVGLLACGLLVPILGLMKLGDGSFV
                     GGIEHVVVNTPWLLNSVGSIDSAVVPWPTLFTGMLFNNLYFWCTNQMIVQKALSGKNL
                     AEAQKGAFLVGVFKILGALFLVFPGIVARNIFGDSLMSNPDNAYPFLVSEVLPKMIFG
                     IFAAVIFGAILSSFAGALNATSTLFSLDFYKPLINKKANDKQIARAGKTVTVVVGIIS
                     IIVAPFISFAPAGLYQFVQEFNGLYNMPLLVIILFAFYSKKATAFGAKTTIAVHIVLY
                     ALSKMLFQNIHFLYVLTALFVLDIIILMVVSKLKPDGEFVLNSFDTKVDIEPWKYTKV
                     TAIALVVIVILTYVAFSPIGFAG"
     gene            7404..7718
                     /locus_tag="JXV47_002617"
     CDS             7404..7718
                     /locus_tag="JXV47_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAX1488622.1"
                     /translation="MHKDLLIICETGISASLLVSKMLETIRAKNLSYEIDYATIRNVE
                     EKLNYKDYDVLLLTPQVARSEEKVKEIIKKEKCTAQIVYIKQEDFRYMNIENIIASIE
                     ED"
BASE COUNT         2395 a         1531 c         1938 g         2211 t
ORIGIN      
        1 taaatgacaa gatttttaag aaattatatt gatggtcgtt gggtcgctag tcgctcaaca
       61 gagtttgaag aagtaatgaa tccggctaca gaagaagcgc tggcgaatgt accgttgtct
      121 agcaaagcag agacagccga agcagttaaa gctgccgatg ctgcgtttca aacttggaaa
      181 aaagttcctg ttcctgttcg cggacgttat ctgttcaagc tgcatcagct tttaacagat
      241 cataaaagtg aattggcgcg tttgatcacg ctggaaaatg ggaaatcatt gtccgagtca
      301 ctgggagaag ttcaacgagg aatcgaaaat gtggagcacg cagcgggaat caccaattta
      361 atgatgggag attctttatc aacagcggcg actgatattg agatcacgaa ttatcgttac
      421 ccaatcggag taatcggagg gatcacaccg tttaattttc caatgatggt gcccttctgg
      481 atcttcccga tggctctggc ggcaggaaat acggtggtgc tgaagccttc agaaaaaaca
      541 ccattgttga tggagaaaat tgttgagctg gttgaaaaag caggctttcc tagcggtgtt
      601 tttaatgttg tctatggtgc ccacgatgtt gtcaacacat tgctgcaaga tccactggta
      661 aaaggcatca gctttgtagg atcaaaaaat gtcggtgaat acgtttaccg tgaaggaaca
      721 aaaaatctaa aacgggtaca agcgttgact ggagcgaaaa atcatgttgt tgtgctgaaa
      781 gatgccaata ttgatcgggc agtcaaggac cttattggcg gagcttttgg ttctgctggt
      841 gaacgctgca tggcagcctc cgtcattgtt ttggaagagg aaatcgcgga tcagtttgtt
      901 gaaaaattta aggctgcggc aaaagcgatc aagatcggca atggcttgga cgaaggggtc
      961 tttttaggac cagtgattcg aaaagatgca cagcagcgga cctttgacta tatccaaaaa
     1021 ggggtcgatg aaggagcgaa actggtacta gatggtcgcg aaaacattcc agaaaaaggc
     1081 tattttgttg gaccaacgat ttttgataat gtcacgatgg atatgaagat ctggcaggat
     1141 gagatttttg ccccggtcgc atcaatcgtg cgggtaaaag atttgatggc agccgttgag
     1201 ctgacgaatg aatctgaatt tgcgaatggt tcgtgtctgt ataccaacaa cgcatcagcg
     1261 attcgctact tcagagaaaa tgttgatgct gggatgctgg gggtcaatct tggggtgcct
     1321 gcaccgatgg cttggtttgc cttttcaggc tggaagcact ctttctttgg tgatttgcat
     1381 gccaatggca aagacagtgt tgagttttat acccatcgga aagttgttac agcacgttat
     1441 gcgcaaagtg agatttaaag atttgcttcg aagctctgtt aaagagcttc gaggattctg
     1501 ttataggcta taagccagag agaggttttt tctgtgaata ttcaactgaa aatgcctgcc
     1561 aatttaagaa ttggcggcgg aacaatccaa tttcttatgg aagaatcaga acaactaggc
     1621 aacaagccgt taatcattag tgatacggtt atggaacaga ccgggcatct tcaaaagatc
     1681 aaggagctgt tgggaaaaac agatgatcaa ttagcggagt atacagacat tcaagccgaa
     1741 ccgacgcaag aaaatgttta tgatgcgctg aagctttttc agaagcatca atgtgatcat
     1801 atcattgctt ttggtggcgg cagctgtctg gatacagcca aggtggtagc cgttttggct
     1861 gctaatcaat taagtctcga agcgattcat gcaagaaatt ttgatcagct gcaagcgggc
     1921 attccgctga ttgcagtgtc aacaactgct ggaactggtt cggaagtaac cgatgtggca
     1981 gttattacca atacaaaaac agcagtcaaa atgatgatga aggatctcgt tttcatgcca
     2041 cagatctcaa tcgttgactc tgattttacg aaaactgtac caccaaaagt aaccgcggca
     2101 acgggagtcg atgcgctatg tcacgctttg gaatcttatg tttcagtcaa agccaatgaa
     2161 gtaacgcaac tattttcact ggaagcgatg aagaaaattt tgaacacgct ttctcaggca
     2221 tatgaaaata gcgacgacac tgaagccaga gaacaaatga gcttagcttc aacggaggcg
     2281 gggattgcct tttcgaatgc gtcagtcaca ttgattcatg gaatgagtcg accggtgggg
     2341 gcactttttc acattcctca tgggatatca aatgcgatgt tattgccggt cttttttgaa
     2401 ttctcaaagg atgctattca gactgagtta gcgacgatcg ccagatttat ttatccggca
     2461 gccgaagatt tatcgctgga agaggctgcg gattatctga ttaaaaaaat ccaagagctc
     2521 tgtgagcagc tgtcgatccc aacgattcga gattatggta ttgatcagca agcgtttatg
     2581 gcagccttag acaaaatggc cgcggatgcg ttgaccagcg gaagtccgca aaataataaa
     2641 aaggtgccta gtcatagtca aattaaggaa ttatacgtac aagcttatgg gtagtaaaag
     2701 gcggagcaaa gagagggctc taccttttaa gaataaaagc tacacaggaa taattttgta
     2761 agcgcatact atgtgtgctt aaacaacaga acagggggat aagtaattga gagtaaaagt
     2821 aggcgttatc ggaacaggtg caatcggcat cgagcatatc gacaggatca atcagaaaac
     2881 acaaggggct tatgtgacag cagtctcaga tatcaatgta aaagctgcta aagaggttgc
     2941 caaacgtgtc gatgctaaat tctttgaaac cggagaagca ttgatcgctt ctgaagatgt
     3001 ggatgtcgtt gttgtgactt cttgggaccc gacccatgag cagtatgtgt tagaagcaat
     3061 caagcatggg aaatatgttt tctgcgaaaa gccattagcg atggatgcag caggctgccg
     3121 ccggatcgtt gatgcggaag ttgcttatgg gaagaaattg gttcaggttg gcttcatgcg
     3181 ccgctatgac cgcggctaca ttgaactgaa agaagcaatc gaatcgaagc aatacggaga
     3241 agcattaatg atgcattgtg cccatagaaa tcctagcgca gatgaaaact acacaacacc
     3301 gatggcgatc agcaacaccg cgattcatga gattgatgtg cttcgctggt tgctaaatga
     3361 agattatgaa tctgttcaaa tgatcttgcc gaaaaaaacc agcaactccc atgccgattt
     3421 gcatgatccg cagctgctga tctttcaaac aaaatccggt gtaacgattg atttggaaat
     3481 ctttgtgaat tgccgctttg gctacgatat taaatgtgat gtggttttcg aaacggcaga
     3541 agtaggaatg acggacccag cctatacacg aattaaatcg gaagaaaaaa attacacacc
     3601 tgtttcacca gattggcaga cccgcttttt ggatgcctat gattatgaat tcaagctgtg
     3661 gatcgattcg atcaaaaatg atgcggttgt cggtcctacc gcttgggatg ggtatgtagc
     3721 agcgatcacc atgatggctt gtcatgagtc tcgtgaaaca aaaacaaaag taatgattca
     3781 aatggatgaa cgaccagcac tatacaatga gtaattctca gaaaacggag gtatttcatg
     3841 aacaacatta gagtaggcat cgtcggttta ggaagattag gaaaagtaca tgcacaaaat
     3901 ttagcaacag gtgtcagttg ttgtgagctt acggctgcgt gcagtttagt tgaaacagaa
     3961 ttagcattcg cacagaagaa attaggcgtc aagcatactt tttccagcta tgaagaaatg
     4021 gtcaaaagtt ccgtgatcga tgcagtcttt attgtttcac catcaggctt tcactgtgac
     4081 caagtccgct tggcgatgga aaatggcaag catgtcttta ctgaaaaacc attaggcctt
     4141 gaagttgaag atattaaaaa gacccaaaaa gtcatcgaag agcatcctga acaggtcttc
     4201 atgttaggct tcatgcgccg ctatgatgag tcgtatcagt atgcgaagaa aatggtagaa
     4261 gatggcgaaa tcggcgaaat cacactgatt cgttgttatg ggatcgatcc gagcgaaggc
     4321 ttggaaagct ttgtcaaatt tgccatgaat aacgacagcg gcggcttgtt cttagatatg
     4381 gcgatccatg atattgattt ggttcgctgg tttaccggcc aagaagtcga tcaagtgtgg
     4441 gcgattggga aaaatgcggc gtatccagaa ttggatcagg ctggtgagct tgaaactgga
     4501 gccgcaatga tgagcctgag cgataaaaca atagctttac tagttgccgg cagaaacgca
     4561 gcccatggct atcatgtcga aacagagatc atgggaacca aaggaatgct gcgggtagcg
     4621 caagcgcctg agaaaaatct tgtgacgatc atgaacgatc aagggatcat ccgtccatgt
     4681 tcacaaaact tcccagaacg attcagagaa gccttcattc gtgaagccca agaatttgtc
     4741 tcatgtattc aagaaaaacg tcaaccagcg gttaatgcag aagatggatt gcaatcaact
     4801 aagatcgcgt tggcttgtca agaatcattc gatacgaaga gtttagtaca actaaaaaaa
     4861 taagcaggag tgtgagaata tgaccaaaca aattcaatta gccatcgcac caatcgcgtg
     4921 gaccaatgat gatatgcccg agcttggtag tgaaaatacc tttgaacaat gtatcagtga
     4981 aatggccctt gctgggttca ccggaacaga gattggcaac aaatatccaa aagatccaga
     5041 ggtgttggaa caatatttga atattcgcgg cttaaaggtt gccagtgcat ggttcagtgc
     5101 gtttctgaca actaaacctt ttgaagaaac tgccgaagcc ttcaaagcac atcgggattt
     5161 cttacatgcg atgggcgcta aagtcatcgt agtagctgag cagggtcata gtatccaagg
     5221 gattatgaca gcgccagtct ttgatgataa accagttttc actgatgaag agtggaaaaa
     5281 actggcggaa ggattagaaa aattagggga tttggcccac gaaaaggata tggagatcgt
     5341 ttaccatcat cacatgggta ccggcgttca aacgacggaa gaaatcgatc gtttaatgga
     5401 aatgactgat ccagacaaag ttaaattatt gttcgatacg ggacatttgg tcttttctgg
     5461 tgaaaatcca atcgcggttt acaaccgtca tcaagatcgt atcaaacaca tccatttcaa
     5521 agatattcgt caagaaacgg ctgaagaagt agaaaaggaa aaagacagct tcttaaacgg
     5581 cgtgaagaaa ggcgtcttca cggttcctgg tgatgggatg attgatttca ctccaatctg
     5641 gacagcaatc catgccagcg actatgaagg ctggatcgta gttgaagcag aacaggaccc
     5701 ggctaaagcc aatccatttg aatatgcagt caaagccaga agctacattc gagaggtcac
     5761 cggtctttaa tctattgaaa aggagctaga cgatgaatct tttttctata atcagtttcc
     5821 tagtgattgt catctgtgta tggttatttg cctattctag atccagaagt gtcgatactt
     5881 ctggatcaga agggttcttc atgggagggc ggagcttaac tgctttgcca atcgccggca
     5941 cgatcatcat gacgaacctg tccaccgaac aaatagtcgg acaaaatggt caaagttatc
     6001 atgcagggat ggaagtaatg gcctgggaag taactgctac gattgcgatc gtagctttgg
     6061 ctgtgatatt cttgccaaaa tattttaaat acggcatcaa tacaatctca gatttcatcg
     6121 agattcgtta tgatacggtt accaaacgaa ttatttcgat cttatttatt gtgacctata
     6181 tgacttcttt cttacccgtg gttctttatt ctggatcgct ggtgttcaat aagatcttcc
     6241 atattgatga gctgctgggc gtccagccga tcgtcgcgat cataattgta gcgatggcaa
     6301 ttggtattgt cggcatcctc tatctgctga tcggcggctt gtcgttaagt gccaatagtg
     6361 actccattta tggagtcggt ctgctggctt gtggtctgct ggtcccaatt ttaggcttaa
     6421 tgaagcttgg tgacggcagc tttgttggcg ggatcgaaca cgttgtggta aacacgccat
     6481 ggctgcttaa ctctgtggga tcgatcgact cggctgttgt tccatggccg acactattta
     6541 cagggatgct gtttaacaat ctgtatttct ggtgtaccaa tcaaatgatc gtccaaaaag
     6601 cattgtccgg caagaattta gctgaggcac aaaagggcgc tttcctagtc ggcgtcttca
     6661 aaatcttagg tgcgttattc cttgtctttc cagggatcgt cgctcgcaat atttttggcg
     6721 atagtttaat gtcaaatcca gataacgcgt atcctttttt agtcagtgaa gtattgccta
     6781 aaatgatctt tggtattttc gccgctgtta tctttggcgc gatcttatca tcatttgcgg
     6841 gagctttgaa cgcgacatcg accttgtttt cactggattt ttataaaccg cttatcaata
     6901 agaaagcaaa tgataagcaa atcgctcgtg ctggtaaaac agtaacggtc gttgtgggga
     6961 ttatctccat tatcgtagcg ccattcattt cttttgcacc ggctggattg tatcagttcg
     7021 ttcaagaatt caatggacta tacaacatgc cgctgctcgt gatcattctc tttgcctttt
     7081 attcaaaaaa agcaactgct tttggggcaa aaacgacgat tgccgtgcat atcgtcttgt
     7141 atgcactatc aaaaatgctt ttccaaaata tccatttcct ttatgttttg acggcattat
     7201 tcgttctgga cattatcatt ttgatggtgg tttccaaatt gaaacctgat ggagaatttg
     7261 tgttgaactc attcgataca aaggtcgata tcgagccttg gaaatacacc aaggtgactg
     7321 ctatagcatt ggtagtcatt gttattttaa cttatgtggc attttcacca attggctttg
     7381 caggctaaaa acaggagggt attatgcata aggatctatt gattatttgc gagaccggaa
     7441 tcagtgcgtc gctgctcgta tcaaaaatgc ttgaaacgat cagagccaaa aatctatcgt
     7501 atgagataga ttatgcaacg atccgaaacg ttgaagaaaa actgaattat aaagactatg
     7561 acgttttact tttaacgccg caggtcgcac gttctgagga aaaagtaaaa gaaatcatca
     7621 aaaaggaaaa atgtaccgct cagatcgttt atatcaaaca agaagatttt cgttatatga
     7681 atattgaaaa catcattgca agcatcgaag aagattaacg agaatctttg attattgagt
     7741 gtcgaggagg tggtatatga aaagatggca tgttcgcccc gatcacccca atatgaaggg
     7801 cggacttatt agaaataccc aatcttgtat ttattcaata gggtaagcgg acctcaatag
     7861 ccagctcatc cccaaaaagt cgaatggaga cacttaaatg agtgtaccta ttcgactttt
     7921 tgagactcta agtcaaatcg tgttgttctc attaaatcac tgaaaggaaa tgcttcggcg
     7981 tttccttttt tctttttgtt tttcttcgtg ttttgaaaat tacttactat ttactatacg
     8041 agtagtttca aataattttg acatcctaat cttca
//
LOCUS       DADGKS010000105         8063 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.109, whole genome shotgun sequence.
ACCESSION   DADGKS010000105 DADGKS010000000
VERSION     DADGKS010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8063
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.109"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            7..1431
                     /locus_tag="JXV47_002618"
     CDS             7..1431
                     /locus_tag="JXV47_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAX1488623.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(1612..2385)
                     /locus_tag="JXV47_002619"
     CDS             complement(1612..2385)
                     /locus_tag="JXV47_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAX1488624.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(2382..3287)
                     /locus_tag="JXV47_002620"
     CDS             complement(2382..3287)
                     /locus_tag="JXV47_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAX1488625.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(3441..3761)
                     /locus_tag="JXV47_002621"
     CDS             complement(3441..3761)
                     /locus_tag="JXV47_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HAX1488626.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            4235..4921
                     /locus_tag="JXV47_002622"
     CDS             4235..4921
                     /locus_tag="JXV47_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HAX1488627.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            4923..5867
                     /locus_tag="JXV47_002623"
     CDS             4923..5867
                     /locus_tag="JXV47_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HAX1488628.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            6066..6710
                     /gene="pcp"
                     /locus_tag="JXV47_002624"
     CDS             6066..6710
                     /gene="pcp"
                     /locus_tag="JXV47_002624"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HAX1488629.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            6789..>8063
                     /locus_tag="JXV47_002625"
     CDS             6789..>8063
                     /locus_tag="JXV47_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488630.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
BASE COUNT         2514 a         1440 c         1684 g         2425 t
ORIGIN      
        1 gcttacatgg atacagagca acagaaaaaa ggaattggtt taattccact tgctgcctta
       61 gtaattggtt cagcgattgg aggtggcgta tttggtatta tgacggacat ctccggatcg
      121 gctggcggcc cagctatttt cagttgggta ctcgtaggaa cagcaatgtt gatgctctcc
      181 ttgtcgatca ataatatcaa taaaaaacgt ccagatttaa aaggcgggat ctttagttac
      241 gcagaagaag gttttggccg tttcgctggt tttatcagcg gttggggtta ctggctcaca
      301 tgctggttag gcaacgtagc ttttgcaaca ttgttgatga gcgcattagg atatttcttc
      361 ccagtatttg aaggtgggca aaatctggca tcgatcgtga tgagtacagt ctttttatgg
      421 ggatatgcat ggctagtgaa tcggggagtc gaaaatgcta gtttcgtcaa tgctatcgtc
      481 acattctgta aattagtgcc attattttta tttattgtag tagctatcag cacgttttcg
      541 atccaacaat tcattgataa cttttctagc gacattatat tgaatgcgaa tggacagccg
      601 atcccgtttt ccagtcaagt attgagttgc atcatggtga tgctttgggt atttgttggt
      661 attgaaggag cctctgtcgt aggttcacga gcaaaaaaac aatcagatgt tgggaaagca
      721 acgattctag ggatattcgg cttgattatt atttacgtct tggtttccat gcttccatat
      781 gggacaatga cgatgaatca gctgcaaacg atcaaggcgc agcctgctat gggctatgtg
      841 tttgaaatga tggttggtaa atggggagca gtcgtgatca acggcggttt gatcatttct
      901 ttagttggtg tttggctctc atggacgatc ttaccgattg aaacaatggg aaacatggct
      961 gaagacggac ttttgcctaa agcatgggga aaactcaaca aaaatggggc accaacttat
     1021 gctatcgtat tgacgacgtt atgtacgaat gtctttttac tttcattatt attcactgac
     1081 agtgcttata actttgctta cacacttggt acagcagcta ttttcttcac gtggcttttc
     1141 ttaggattgt accaaatgaa actttcttat cagcggaaag aatgggtcca atttttagta
     1201 gggcttttag caagtgcctt tcaagtatgg gctatgctag tcgtagcctt taatgaagta
     1261 atgcttgttc ttgttctttt cttgccaggc atttattttt acctcaaagc acgtaaggag
     1321 caaaacgagc ctgtacaaca tatccactta gataagattt tacttatagg tgtgacgatg
     1381 gtcggagtga ttgcaatggt tttatttgcc actgggatgc ttcacgtata gaagtataaa
     1441 agaagtataa agagaggttg tgagcctgtc gtttattcaa aaacatacta ggaaaggagc
     1501 tgtgacacaa atgttgtcac agctcctttt tcagaataaa cggtgtttaa gagacagcca
     1561 atcggcaata aggctgaacg tctctttcac agcctctttt ttgatgagtc atcatacatt
     1621 ttttcgctta aatacgagat atcctaatgc taagaacaaa acgatgtaag ctaaattacc
     1681 gaatagcatt tgattagtag aaagatgagt caattgcttc atgatctctt cgtttccaat
     1741 ttggttttgc agattcaaca tactgatcgg attccatttg atccactccc atttttggat
     1801 gagtgcaata aggataccag atatgattga cgaagcaaaa taaaagacga ttcctgctga
     1861 gatggatgcg ccggaactat tgataaagca agcaatcatc aacactaaac ttaaaatcag
     1921 ccataaaccg atataactac ccaaagtata agtgaacaag ctttggatca gtgtttgacc
     1981 agtagaaacc ttctccgtga aggaaatcga agggaaaaga atcagtttca tcaacacagt
     2041 gacaataata gctaaaaggt ataaataaac agaataaata actaatgtga tccatttgct
     2101 tactaatatt tctcctcgag aatactttcg ataaaggaga tttttcaatg taccatattg
     2161 tgcttccatc gaaatgatcg tgcttgcagc tgcaatcatg ataaagacaa tccaagatgt
     2221 ggcactaaaa agctgagcag tcatttcaac tggatcaatg atcgtcgtgt attttttggc
     2281 tagaagtgct gttcctatga gcaaaacaac taatagaaca gataaaacag cagttgactt
     2341 tttcttgatc aatttaaata attcttgttt tacaagcaat gtcatttttc ttcttccccc
     2401 tttactgaat ccagaatttc caatagagaa gattccaaat cattcgtcag atgctggacg
     2461 tctgtcacat ggatattttg tgcagacaat agctggatca cggttcctaa taattcttcg
     2521 ttttctttta aaagcttgat tttatcagga tcttccaaag tatatccagc ttctgtcaag
     2581 atcgttcgag cagctagatc atttgttgta gagataacga tgaaatcttg cgctgtttgg
     2641 ttcaattcag ccattgtaca ttgtttgatg atctttcctt gattgatcag gatcagctca
     2701 tcgaccattt tttcaagctc gctgagtaag tgactggaga tcaagaaaga ggtgccctga
     2761 gtagccaagt cggtaatgat ttttcgcaca tctcttgttg cttgtggatc caaaccgttc
     2821 atcggctcat ctaaaataac gatagacgga tggttcagta aggcaagagc aattcccaat
     2881 ttttgtttca ttcccaacga gtaggatttc gcttttttgt gaatgtactt ttccatcttg
     2941 agctgattca cgatagtgtc gatagcagat acatcgttgg tttcagagaa taacttcaga
     3001 tgatcatagc ctgttaagaa tggatagata cccgggtatt cgatcaatgc tcctacttgt
     3061 tccaaccctt tatgactaga gggagaaatc tcattttcac caatacagat tgttccatct
     3121 gagtaatgga tcagtcctaa aatagctttc atgatcgttg tttttccagc gccattagga
     3181 cctactaatc caacgatttt gccaggggat aagctaaaac tgacatcgct gagggcttgt
     3241 ttgtgaccaa agttcttgga taattcttgg accgaaagac ttttcaaaaa tattcactcc
     3301 ttttctatag atagtacaag catacacctg atgagtggag aagtcgctag gtcattggac
     3361 ttatttctta ttttttcata aaaaaattga atattaaata aaaaggctta ttttttctga
     3421 tcagtactta ttccaagtgt ctagtggccg ctagtaatct tgatgccaat gatactgatg
     3481 agtagcatcc ccacaaagaa ccaagtggaa agattcagct tatcatgaaa caagaccaca
     3541 ccaattatga ccgaaccaac tgcgccaatc cctgtccaga taggataaga gagactcatc
     3601 ggcaaacttt tgattgcctt tgacaaaaag taaaaactag caatcatgcc aatcactgtg
     3661 taaaaagaat aattgatttt agaaaaacca tcactccatt tcatcatcgt tgaccagaat
     3721 acttccaaaa ttcctgctat gattaattcc atccatgcca tacttacatt cctccttaac
     3781 tataaaaaaa tacacaaaaa gaggaaaatc atcccttcaa agacctaatg gaatgatcat
     3841 cctctttatc ctacccggtg gcagattgta tatctttttc tgtagtatag cacacctatc
     3901 cagatatcgg caatctcata ctttttagta aagtgtacca agcactgacg gatatatcgt
     3961 tagcggaaaa gaagatgaat gctttgcaat ttcatagaaa gaagttgtta tttattaatc
     4021 atttaaaaaa aacagtaact agaccttatt tctatatatt atcgggcaat aaattaaaaa
     4081 aagctttacc ttacaataag taagataatt tttgtgataa aaaaataacg aaaaatattt
     4141 aaaaatagtg tctatttcgt gagaaaacaa ctatattttt tatgtgtttt gctttataat
     4201 taaaaaaata ttgtcatttt atggaggaaa atatatggaa aattatctta gccttttagg
     4261 cgtcttgatt gttattctcg ggtttgcatt taaattagac tcgatattga tcgtaatggt
     4321 tgctttagtt gttacagctt tgactggcgg tcttggcatt caaggaatgt tagaactttt
     4381 aggtacaagt tttgtaaaca atcgcgggat ggcgattttt atcatcatta tgttggcaac
     4441 aggaacgctt gaaagaaatg gtctgaaaga atcagcggct tccttgatca agcgattcaa
     4501 gaaagtatct gctggtatga ttgtagatat ttatgggatc tttcgaatga tctttgcggc
     4561 ttttaacgtg agttttggtg gagttgctgg atttgttcgt ccaatcattt taccgatggc
     4621 attggggacc atcgaatcaa aagggttaga agtccatcct aagcatgaag aagaactaaa
     4681 aggtatggct tcagctatgg aaaatgtctg ctggttcttt ggccaagtac tattcatcgg
     4741 aggagcaggg gcgttgctag tccaatcaac actgaaagat ctaggatatg acgtaacatt
     4801 gggacagctt gctttagtgg aagttccagt ggctatcacg gctttagttg tggcaagtgt
     4861 ctacttctat cttaaagaaa agaaattagc gaagaaatat tatccaggaa aggggcaata
     4921 agatggactt ttttacaaat cctgatattt tattaggcga taaattactg gagatccttt
     4981 atatcgtgat gggactcgta ttgatttaca ctggagtaag aaatttaaca gataaaacca
     5041 atcctcatcg ttatgggtca gcctttttct ggacggtctt aggggtagtt attgcaggag
     5101 gaagatggct tccggcaatc gtgaacggtg gcttgatctt tgcgatgacc ataccagcaa
     5161 ttgctaagaa agtcagcaaa ggagaaagcc ggcttccatc aaaagaatat atggaaaaaa
     5221 tgtcagacaa actaggaatg aaaattttta ttccagcttt gagtatcggt gtctttgcga
     5281 tcttgtttgc tctatttacc aatttaggtg ctttagtcgg cgtgggcgtc ggtgtttttg
     5341 cagccatgct aatcttgatg ttcttttctc gagataatcg accaagtaca tttttagatg
     5401 atgcagcaga tatgctgggc acagtagggc cgttaagcat gttgccaatg cttttagctt
     5461 ctctaggtgc ggtatttaca agcgctggag ttgggacagt gatttccaat gcagtaggta
     5521 cgatcgttcc agaaggaaat gtgaacatcg gcatcatcat ttacgctctt ggcatggtga
     5581 tatttacggt aatcatgggg aatgcatttg cggccatcac cgtgatgacg gttgggatcg
     5641 gtgcaccatt cgtatttagt catggagcga atccagcgtt aataggaatg gttgcattga
     5701 cttgcggttt ttgtgggacc ctgctgacac cgatggctgc taacttcaat atcgtgcctg
     5761 tagcgatgct ggagatgaaa gacaaatacg gagtgatcaa aaaccagttg tttattgcgt
     5821 tatttatgct agttttccaa attgcttata tgattctatt taaataatag aagagagggg
     5881 ttgtgacaga ataattgtcg caacctcttc taacattgta gtggaacact atttttttat
     5941 aagaatatat taagtttgat ctgttatgtt atttaaacta ttgtttcctt tatttacgct
     6001 gttcaaggaa aatggtatga taaaagataa ccatatgtta aatcaatcgg acggaggaac
     6061 aacagatgaa agtactagta acaggttttg atccatttgg tggggacaaa gtgaatccag
     6121 cctatgaagc agtaaaaaaa atgccagatg aaatcagcgg tgctgaaatc atcaaagtgg
     6181 aagtaccgac cgtattcgaa aaaagcagtc aagtagtcaa agaagccatc caacagcacc
     6241 aaccagatgt cgtgatctgt gtcggacaag caggtgggcg gtcagcagtc tcgttcgaac
     6301 gtgtcgcaat caatctagca gaagcaagaa tccctgataa tgaaggaaat cagccattcg
     6361 atacggcttt agaagaaaac ggtccagccg cttactttac ctcattgcca atcaaagcaa
     6421 tgacaaaaaa tgtacaagat catggtctac cagcgtacat ctcttataca gcaggaacat
     6481 ttgtctgcaa tgatatcatg tatcgtttgc ttcatttgat cgaaacacaa ttcccggcaa
     6541 ttcgaggtgg gttcatccac gtgccattct cacccgatca agtgatcgat cgtccagtgg
     6601 gtacgccttc tatgtcttta gaagacattg cttcttcttt gacttatgca gttgaagcag
     6661 cagtagaaaa taaagaagat atttccggaa atgccggaac aactcactaa tttagcaaga
     6721 aacactggct ggttgctaac gttatgttag tagccagctt tttgtaatta gaaaggaaag
     6781 aaacagccgt ggaagaatgg caatccgtct ttgaagaatg gtttccaaaa gaaatcagca
     6841 aaagctatcc catcaaaatt tctaaacaat acacaagcag tcaacgttgg gagatctatg
     6901 caaaattaac gaaaaaacag cgggaactag tcgataagca ccgccgatat ctaatcagct
     6961 ctcgttttat ggaagaacat tatttagctg caacagattg ggtgttttct gacttcaaga
     7021 tcaatccgtt ttttcgaaca aaacgaagcc agcaaaaatt gtattgtgag tgtggtagag
     7081 aattaaaagt gcaatacatc gttaaatcgc caaaaaccgg aaagatccta aaactaggca
     7141 tcaaccactt tgccgatcac ctgcatgtct ctccgacagt ggcagcttcg atccatcagg
     7201 gaatgacaaa agttgatctg gccttagacg aattattatg gcttaagcag aagaatatcg
     7261 attttcctga aggactatgg caaaaatact gttttgtctt gtaccaaaat cgtcggatga
     7321 aacagccata tttaccggat ataaaattag ctcagcggct cgcagaattt cgccaagtag
     7381 aaatgccgat ttacatagcg gattatcaag cattggaaaa tgaaatcaag aaaataagtg
     7441 aacacatcaa tgggcagtca aaaaagcgac agataaaaaa agaactattt gacgactttg
     7501 cagaagaatt agtaaaggat gtagaagaat tcttgatcaa ctatcgcgca tttttacgta
     7561 aagattggca atccatcgta tatgaagaag tgccagtaca tcctaatgct tattttgaaa
     7621 catttatttc cgtgttgaga aagacaaaac gtcaacgaac accagaagtc actgctcaga
     7681 tggaatattt tgcgaaaaac caacgattca tccaaccaaa aatctatcta tttatttgga
     7741 agcaatattg tcgctatggt tttacagaag ggttcttcga cagcattcct cggatagtca
     7801 gaaatggttt tttaaaagta ttgcgtaaag aacgagaagc tatacaatct gctgataaga
     7861 aagaccgtac agtctcaaaa gaaaaatggc aactagtagt gaaagatatc caatctggaa
     7921 atgtgcaaga gacaatcgac aaatggaaag gaaaacatta tcgttttact gaagctcaga
     7981 aacaagcgtt ggaatattat cagaagttag aagaatcact gcgtttcaat gatgaggcaa
     8041 gaaagtatct gaaggaatta cta
//
LOCUS       DADGKS010000106         7948 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.111, whole genome shotgun sequence.
ACCESSION   DADGKS010000106 DADGKS010000000
VERSION     DADGKS010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7948
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.111"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(379..1071)
                     /locus_tag="JXV47_002626"
     CDS             complement(379..1071)
                     /locus_tag="JXV47_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAX1488631.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            1156..1332
                     /locus_tag="JXV47_002627"
                     /pseudo
     CDS             1156..1332
                     /locus_tag="JXV47_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
     gene            complement(1508..2077)
                     /locus_tag="JXV47_002628"
     CDS             complement(1508..2077)
                     /locus_tag="JXV47_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAX1488632.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(2151..2474)
                     /locus_tag="JXV47_002629"
     CDS             complement(2151..2474)
                     /locus_tag="JXV47_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488633.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2628..3440)
                     /locus_tag="JXV47_002630"
     CDS             complement(2628..3440)
                     /locus_tag="JXV47_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488634.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3794..4642
                     /locus_tag="JXV47_002631"
     CDS             3794..4642
                     /locus_tag="JXV47_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HAX1488635.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4787..5728
                     /locus_tag="JXV47_002632"
     CDS             4787..5728
                     /locus_tag="JXV47_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HAX1488636.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVCLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5718..7889
                     /locus_tag="JXV47_002633"
                     /pseudo
     CDS             5718..7889
                     /locus_tag="JXV47_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2386 a         1555 c         1411 g         2596 t
ORIGIN      
        1 tttgatccat cattttctct ccaatcattt tattaaaatc attaacaaaa atattataat
       61 aggatttaag taagttctaa ctaatcacat ataaaaataa aaaaacattt gtattttatc
      121 aaagttttat tatacttgtc aatttgtgta catcctaaaa tataagctat ttgtttactt
      181 ctgtagaata tatactttgt tgttagataa gttgcacatg tttatagaat ctaaataata
      241 aatttttatg taccgcccct caaagtgaac tgaaccccaa aagttgaact atttaatgga
      301 ctgtttccga tattctactg gagatagtcc attaaatagt tcaacttttg gggttcagtt
      361 caaagagggg gggatttttt atcgttgtgg aatatttaaa taccaacgct tgtcatgaaa
      421 atcttgtgct ccacccttag tatttccttc tggatcgttt gtcgcacgca tcatgacgta
      481 tactttctta ttagggaaat cacgcatatt gaaagataca tgatagccaa catttcctaa
      541 agtattataa gcttgattta cgtctggtct ataaatccca tcagctctta ctctagctag
      601 ttcttttcca gtattgtagt ccataatgaa aatatactcg tatttataat tagcaatgtg
      661 ccatccagct acatgcaagt ttgcgttttc gatttctccg aactgatcaa tgtgggcgta
      721 atttgttcca tctgtcagcg tagaatttgc agcacctgct cgagttggat caattactgg
      781 tttatcctcc gaagtagttg gattatcatc cgtaaaacca tgagccaaat cataggctag
      841 tttttcttta cttacaccca tttcagaaag ataaccgtaa ggatctgtat gatcgcccca
      901 aatattttgt gttacccata aatgcgattt gattcctggt tggttataag gagtgtctaa
      961 tgttaatgga ataccatatt tcattgctga atctcttgcc aattcaacgt atactttata
     1021 gttcttttca aaagtttctt tatcatgtgt atgttgtaac tcgatttgca caggactttt
     1081 ggctcacgag gttgtcctac tctacatctt gctgatagat atgctgaaag gaaaacacca
     1141 acattatgtt ttgctttttc agctagaacg agacaagcag gaataccttt agaagatatc
     1201 aaaggttttt taggtcataa agatgtttcc actacacaag tctatgccca tatttctccc
     1261 gaagtgaaaa aaagatcaat gaatcaacta gaaaactata tagaagagca aataaaaaag
     1321 cactcaaatt gagtgctttt ttaagctcac tatcactaaa actatcacta attttattta
     1381 taagcgaaca tgtttctatc actgattttt taaatctagc gaaaaaccct tatcttaaag
     1441 gcgttcgttc aattctttgg caaggtcttc aaagcctggc ttgcctagaa gtgcgaacat
     1501 ggttttctta tagctcatgt agaaaaattt tcttgatgat gattttatcc atcaattgag
     1561 attgactgtt ttgctctcct atgatttcag ctatgattgt ccgattttgc ggttttcttc
     1621 ttaactggta gttgattttc ccagtttcca tcaactcgct aagcatatcc acgactccgc
     1681 caaatccggt ctttttcgta ataaaaccta gtgctaccat tcgttcatct agattttttg
     1741 ctgtaatcgt cacaccagta atgagcgagt gctgtaatgt ttgggccagc tcttccatcc
     1801 cttcagcatt ggatacgacg gaagctgttt tgttaatagg ttcttcgttt atttcttttg
     1861 gttctttcct ctccactttc actgtttgac gaaggacatc tagttcttgc aagagcgttt
     1921 cgtattgttc ttgggtcagc atcacgccag ctactttttc acgattaaat atatatacgc
     1981 cagttcccgc gtctcgcgct tgagcaaata catccatcgg cgatcgtttc acttctgtga
     2041 tcgaagatgt gggaacttct aatttcttta attccaatgg atttcctcct ttactaatcg
     2101 ctttttatta tagcacagac tgacttgttt tgatcttttt tccaaaggtt ttatcggttt
     2161 ttgcctaacc agtaattgat atcggtaaga agtctttcga taccaaatga aggatggtac
     2221 agatacgttt tttgatcttc gttatggtct agtggaaaaa aatgatcgat gatcactaga
     2281 tctgcatacc gaggcggctt atttcgagta catacatgta tagagatccg ttttcgatgt
     2341 cttagcgttt tgttcagtac cccagcaagt cttcttgctt cttggtgttc atagcgaaaa
     2401 aaaaagacga ttttcacttc aggagggtgg acatctaaat accctcgttc ctggagtgtt
     2461 ttcagtaaaa gcatccccca ctctactgcg gggtgtgcaa gtgcttgttg gatcgctagc
     2521 cgaaattgat atagtttatc tttggaattg ggaaattttt ctaatgtttc ctgataataa
     2581 cgaacttctt ctatcagccg gtcatggata ccaattacgt aacgaagtca ttcttggtaa
     2641 agtacttttg tcagctttga tttgctttcg ctctcaaatt cgctattcag ccaaaacagc
     2701 gaatcaagct tttcagtcac aatcgtcaat ttccgatagt cttgtgtctc ttctatccgt
     2761 ttccaccgct tttcagtaat ctggttacag ctcaagcgca aaattgctag ataatttttt
     2821 tcttttattg gcaaaatctg ctcctctcta aatagcaatt caggaaacaa ttcaaagaat
     2881 agtgttcgac tgtctcctaa aatctcgatt tctgccggat cctttctttg cttcaataat
     2941 tggatgaaca tctcagaaaa ggactgctct ccatcatctg caaaaaaatg cggaaaatct
     3001 ttcaaaaagc aaaacagcag atatcttact tttctttctg aaccaaagat ctgtgctttt
     3061 ttataagaaa aagaaaggtg gtactcgcca aaccactttc tcaatcgctc ttgcgtagaa
     3121 cgatcgtact tctgctcgta aggttcattc aatagcagat ttttcagtaa acaaaacggg
     3181 ggtgattgga tcagaaaaac aaacaagaga taaggttcgc tatatccttg atcataaact
     3241 aactgaacgg ttttcttatg aagaatcagc tgaatgggac agtcgctttc cgccaaacgt
     3301 ttcagatgcc gatccactgt tttaacatcg attttcagtt cttcagctaa atcagctttt
     3361 cgccagatca aatctttcat tagattgatt agtgaaaata aattctgtgc attttttgat
     3421 aatagttttt gccatctcat cgatcatttc tcacctgatt tctaaacata ttgtttgatc
     3481 aaaatgggtt cactcctaaa aagataaaaa actccctttc tatttattta aatacgcaaa
     3541 tcttcctcat tattttttat tttactcaat ttaatcgtat tctcatttca aaacgaatgt
     3601 actttaaaaa aacataataa gatcactttg cttgtaggat gtattccctt ccattacaat
     3661 gaaataaata gcgattttat gagaaggtga tgtgaaaatg gaagaaaaaa tagaagaatc
     3721 caaacaaaaa atcgatcagt tgatataaga attagaaaaa gcggtcatcg gcaaacgttc
     3781 aactatccaa ttgatgatcg tggccctatt agcaggtggt catgtcttat tcgaagatat
     3841 tcccggtgta ggtaaaacgt tactggtcaa agcactagca aaagctgtac agggaacctt
     3901 cagcagagtc caatgtactc ctgatctgct gcctagtgat attcttggtt tttccgtata
     3961 caattcacaa tcaaaagagt ttgaatttcg tccgggaccg atctttacca cgatcttgtt
     4021 agcagatgag atcaatcgta cgactcctcg tactcagtca gcacttttag aagcaatggc
     4081 cgagaatcat gcaacgatcg acaacaatac ataccctcta gacaatcatt tttttgtctt
     4141 agctacgcaa aatccaatcg agtacgaagg aacatatcct ttgccggaag cacagctcga
     4201 tcgtttttta ttccgactac aaatcggtta tccttctttt gatgacgaac ttttgctact
     4261 tttggataaa ttcgaaaaag tgttggataa cttaaatgaa gtattgaaca gttatgaaat
     4321 agaagaaata aaaacaaatg tggcgaatgt ctttgtcagt cccgaagtgg catcttatgc
     4381 cttgcagtta gtgtcagcaa caagaagtca tgctgccatc cagcttggca tcagtccacg
     4441 aggaagcctt tcctttattc aggcagcaaa agcttatgct ttaatccatg ggagaaatta
     4501 cgtcacgccc aaagatttgc aggatttagt tccttacgtg ttttcccatc gcctgatttt
     4561 ttacgatcgt tcattgaagg aagacgaaaa gaaacaaatc attcatactc ttgttgcaca
     4621 aattcctatt cctgtgaggt agattgaggt agacaatgga aaaaatcaaa gattatttca
     4681 ttaattttgt gttatttctg gtatatttca tcattgtgct ttttgctctt gtattcaaca
     4741 attctttagg ctggttcttg ttggcctttt ttactcttta tgtatcatgg agcttgattt
     4801 cattaagcag ctttctaaag aaactttcgg ttacttgtac attgcagcca ctcgtttatc
     4861 gcaaaaaaag tatgcaggtt attttttcca tagcaaaaaa gagaactttt tctttacctc
     4921 tccctcgttt acaaatcggc ttcccagcaa tctttgcaga aaaaaacaag agattttgat
     4981 tcttacaaat aaaccgcaag aagtccaatt gctttggcag ccaaaagaaa gaggatgcca
     5041 tgaaacatta actgtcattt ttacagccta tgatagtcta ggacttttca gaaaaagtgc
     5101 aaaaagagag atctcttttc ctgtgactgt tctgcctgct ttttgtaaga ttcaagcaga
     5161 aaaattacag agagttctgg aaaaaaaaca gcagctgaac gcgtaccaaa gaggtcttga
     5221 ttttcgggaa catcgcgctt atcgtccagg tgattctttc aaccgaatcg attggaaatt
     5281 gtctgctcat actcaagagt ggttataccg tgaatacgat tatcaagaag aagaatgttc
     5341 tcctcttttt tgcttttggg gttcgcccag tccaaaattt gaacctctgc tagacttgta
     5401 tttttcttta tggcatttga gaaaagaaaa gcagccggaa cttctgatat taggcaaccg
     5461 cgcctttcat ggcaaagacc ccggtcatac ctattttgct tctttggaag ctggcgatga
     5521 gaaagctttt ttcgcacact tgaaaaaata tgcaaaaaaa caaatcgtcc tctttgttcc
     5581 tgagaattct cctgaagtct cagaagctat tgaaacattg tcaaaagatc gaacggtttg
     5641 tcttgtttat ttcgtagaaa aacaactcat ggtccaagaa aaagacaaga tatgttcatt
     5701 gccaggaggt gaatggattg acgattaaac gggaaaaatg gctgcgtggc gtttactcct
     5761 ttgtgatact aagtgtaggt gctccgatat ttgtagtagc taatcaattg caaaacagct
     5821 accttcttat cctaactatt ggtgtcctat gccttattgt ctgctgtatt cctaaaaaat
     5881 gggtacgttt gctgctttct ttgccagtaa tgataggttg tttgttttta tattttcctt
     5941 cgaagacatt ttccatatta tggatcttac agtttttttc gtcagtcaca gaggaattct
     6001 tccatctatc ccaaggtaaa ctttattatt tgccagaaaa gacagctttt tttctcataa
     6061 tgttgctgat ctatttattt attacattga ccgtggatta cgactattgg tacgcaccct
     6121 ttctttcttt gatggcttac ttcatgatgc ttaccgtttt tcggaaaaaa gatttactgt
     6181 acgaaatgat tgcggtagta actgttttgt tcgtgtatct ggcagcaagg caatttttct
     6241 ccatccggtt gttgtcggga aacactcgat tccagtcatt gactacagtt ctgcttattt
     6301 gtttcttaac ttttagcgct atcttgcctt tatatcttcc gaaagtacac caatctctcg
     6361 aggaaacgag tgaaccgatc cgagaatatc ttaatgatga agggctttat gacacactcc
     6421 atgagtatca attaaccgga agtgcaagaa caggcttcag tgagaatgat gaacagcttg
     6481 gtggaccttt atatgataat ggcgaagttg tttttacagc gaaccaaaaa ggaaatggct
     6541 attggaagat cgaaaataaa aatcattaca ccggttctgg atggatagaa gatcaggacg
     6601 cacccatcca accaatccaa gaattccctg ttgacatcac gagctaccaa accgttatag
     6661 aagacaaaga aaacattaca ttgaccctaa aaaaacaagt tttcttacct tatccttatg
     6721 gaaatactac cttgactgat ttttcattag ctagtggaca aacgctttac tatttgcctg
     6781 aaagccagcg attcattcct gtcccgaatg aatcgacacg ttctgcaact ttacaaacag
     6841 aaaggttagt ttttacgaga gaagaattaa aaagcagtca gttaaaagct gatgatttag
     6901 aaaatcagca gacaaatctt caattgccaa aaagtttgcc taaacgtatt gaggacttgg
     6961 cggtcgaatt gaccaaaaat gaagcaactt taattcgtaa agtcgaagct gtctaacagt
     7021 atttaaaaac aagcggaaat ttccgctatt ccaaaacgga taccgggcat actccaaaag
     7081 aacacgatta tgtggattat ttcctctttg attcaaaagt cggctattgt gacaactttt
     7141 caacttctat ggtcgtcctt cttcgaacac ttggtatccc agctcgctgg acaaaaggtt
     7201 ttacaaatgg gctcagaaca ggcacagata atcaagggaa tgaggaatac agcattctca
     7261 atagtcatgc tcattcttgg ccagaggtat actttcctgg atttggctgg cttccatttg
     7321 aaccaacccc ttcatttgcc aatccaatgg gttcacaacc agttgctgaa acaaccgaaa
     7381 ccgtccagcc tgctatcgaa caaccaaatg aaagcgaaaa tatggcagaa actatttcca
     7441 gtgagagatc tgaggtcatt ccatcagaag aaacaacact cacaccagct tataaaatcg
     7501 tcttattcag ccttggagtg tgtttatccg tcttgttgtt ctttctattg ttattcagaa
     7561 aatctctgcg ctggacaagt tatcttatct atcttcattt ttttgcttct actaatacga
     7621 ttgcatatca aaaacttctt aaccctttgg aaacattggt accgcgcaaa cccgcagaat
     7681 ctttgcagga atatagcctg cgaatagaac aagaattcaa gctagatctg cgtttcattc
     7741 gattaactac tcaatatgaa gcagaaatat atggacgaca agcagatccg gtaaaattcg
     7801 ataaaaaaac ctatttagaa ataacgcata taataagaaa aatggtatac aaaaaaattc
     7861 tgacaaaagg gagccgcttc aaaaaataag ataaaatttc tggagaatct acttctggaa
     7921 tgccgagaac cagctgattg agtatcga
//
LOCUS       DADGKS010000107         7797 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.112, whole genome shotgun sequence.
ACCESSION   DADGKS010000107 DADGKS010000000
VERSION     DADGKS010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7797
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.112"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(105..629)
                     /locus_tag="JXV47_002634"
     CDS             complement(105..629)
                     /locus_tag="JXV47_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1488637.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="JXV47_002635"
     CDS             complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="JXV47_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HAX1488638.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(1218..2198)
                     /gene="pta"
                     /locus_tag="JXV47_002636"
     CDS             complement(1218..2198)
                     /gene="pta"
                     /locus_tag="JXV47_002636"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HAX1488639.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(2351..3031)
                     /locus_tag="JXV47_002637"
     CDS             complement(2351..3031)
                     /locus_tag="JXV47_002637"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAX1488640.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            3157..4026
                     /locus_tag="JXV47_002638"
     CDS             3157..4026
                     /locus_tag="JXV47_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAX1488641.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            4052..4567
                     /locus_tag="JXV47_002639"
     CDS             4052..4567
                     /locus_tag="JXV47_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488642.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(4614..5177)
                     /locus_tag="JXV47_002640"
     CDS             complement(4614..5177)
                     /locus_tag="JXV47_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1488643.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(5232..5411)
                     /locus_tag="JXV47_002641"
     CDS             complement(5232..5411)
                     /locus_tag="JXV47_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488644.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(5488..5997)
                     /locus_tag="JXV47_002642"
     CDS             complement(5488..5997)
                     /locus_tag="JXV47_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488645.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(6093..6473)
                     /locus_tag="JXV47_002643"
     CDS             complement(6093..6473)
                     /locus_tag="JXV47_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAX1488646.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            6803..7552
                     /locus_tag="JXV47_002644"
     CDS             6803..7552
                     /locus_tag="JXV47_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HAX1488647.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
BASE COUNT         2232 a         1614 c         1382 g         2569 t
ORIGIN      
        1 tattcaaaaa aaatggactg cgacacgact tttgtcacag tcccttcgtg tgtttttctg
       61 ccttctcaaa aggatgacag tttctcactc ttttcctatt tcttctattc aatcaaataa
      121 ctcattttat atacatctaa aaattcacct agatctgttc ttgcccctct aggcatgacc
      181 gcttcgattt ggaagcccat ttttcggtaa aggtgtacgg ctctttcatt acgaacttga
      241 acgtcaagct ccaatcgaaa aagtacaccc atttccttcg cccaactgat gatttcttct
      301 agcataagag tgcctagtcc cattccccaa tattcctgca gaatactgat accgacttct
      361 cccacgtgag acaaacgaaa ttgactgtct gccttgacag atgctgttcc aataatcgtc
      421 ccttcataga ttgcaagcag caataaatta ttattgcttt cgtatatata atccaactct
      481 tcttctaagg tttctggtgg taacaggagt tctgcttcat ccaaaactaa aaattctgtc
      541 tccttattaa cttgtcccat catcaaaaga atgtcttttg catctcctgg cactgcttcc
      601 cgcaagatga tcccaacttc ttcactcatg attttcagcc catttttcta gaattcgctg
      661 tttgaaggtt tcactttgct ccccgtatga gattagtttc acataccgct tttctaaatc
      721 tgtatcactt ttttctaaaa tcagttccaa ataatcctcc ggcagtgctt cttctaatag
      781 atttccccat tcaacaacgg aaagcccatc accttcaaaa tattcatcta accctaaatc
      841 tgctccgcta gctgctaccc gataaatatc catatgatac aacggaatcc gaccttgact
      901 atattctcta ataatcgtgt atgtcggact tttgatcatt tgcgttatcc ctaatccttg
      961 ggcaattcct ttcgtcaacg ttgttttacc cgcacctaga tcaccagtca atatcagatt
     1021 gtcacctggc attgcggaat gaccaattgc ctctgcgaat tgttctgtca ttgttaatcc
     1081 tgatagttcg atcatttttc atcttctccc gctcttcttt ctttttgcca gtatatcgcg
     1141 taatgaagtt tttttaaaga aaaaatgaac tagtcaagaa cagcagctgc tgtttttggc
     1201 tagttcgcgt gtatttgtta atcaatcaat gtttgtgctg ctgtgataat cgataattta
     1261 tatacatctt cttcatttgc tccacgagac aaatcagaaa ccggtttgtt caagccttgt
     1321 agaattggtc cgattgcttc aaagttaccg aaacgctgag caattttata gccgatattt
     1381 cctgactgca attctggaaa tacaaagact gttgcttgac cagctacttc tgaatctggc
     1441 gctttcagtt gtgcaactga aggaacataa gaagcatcaa attgcaattc gccgtcgatc
     1501 atgtattgtg gcgctagttt tttagcgatt ttagttgctt caactacttt gtctacttct
     1561 ggcgatttcg ctgagccttt tgtcgagaag ctcatcattg ctacttttgg ttcgatatcg
     1621 aacaattctg ctgtttttgc agaatctacg gcgatttcag ccaattcttg cgcagttgga
     1681 ttcacgttga tcgcacaatc cgaaaagaca tatttttctt gatctcttcc acgtaccatg
     1741 atcatcgctc cgcttgtccg actgatgcca ggctttgttt tgatgatctg aagtgctggg
     1801 cgaacagtgt cgccagtcga atggatcgct ccagagacca ttccgtctgc aatccccata
     1861 tacgtaagca tcgtaccaaa gtaattcaca tcttttaaaa tcttttctgc ttgttctttg
     1921 gatgcctttc catttctacg ttcaacaaaa gtatccacca tttcatccca cttatcgtaa
     1981 ttatcagggc tgatgatcgt aaagctagat gttttgattc ctctggcatg cgctgcattt
     2041 cttatttctt cttcgttccc tactaaaatg ggttccacaa gttcttctgc tttcaaccgg
     2101 gcagctgcgc ctaaaatacg agcatcagta gcttccggga aaacgatttt gatcccacgg
     2161 cgaacaattt taaatcttaa actatcaaac aattccacaa gatgacctcc agacgttttt
     2221 atatgtatta tcatacacta ttccagaaaa aaagaacagt ttattttatc tgtatcagtc
     2281 aaaaatgctg gaaaaattaa gtttttcaca tacaaagcga actgcactat aacaggaaag
     2341 cgctgtttta ttacactgtt tcaggcagtt gccaatcaat cggttcttct cctaacgcaa
     2401 ggagcgcatc attcgttttc gagaagggtt tggaaccaaa aaagccacga cttgcagata
     2461 acggactggg atgtggagat gttatgatga tatggcgact cttatcgatc attttgattt
     2521 tttcttgtgc cggttttccc cacaagataa acacgattgg tttttcccgt tcatttaatt
     2581 tttcaatgat cgtgtctgtt aatctttccc aacctttccc gcgatgagaa tacgcttgcc
     2641 cttcccgaac ggtaagaacg gtgttgagta aaaggactcc ctgtttagcc catgacacta
     2701 gatttccatg ttgaacaggt gcgattccaa gatcatcata aagctcttta tagatatttc
     2761 ttaacgatgg cgggatcttt acgccaggtt gcacagaaaa agataagcca tgagcttgat
     2821 tttctccatg ataaggatct tgtcctaaaa tcaccacttt aacttcttca taaggagtca
     2881 attccaatgc ttcatagata tgatacatat ctggatggat cttttgggac gcatattctt
     2941 tttttaaaaa ttctcttaga tgcagataat aatcttttga aaattctgag gacaaaactt
     3001 cttgccaact gttatgaatg atttctttca aaaactccac ctcctaataa aaagaataac
     3061 tcacattttc ttcaatcaca agggacaatc ttcaccctca gcacttgatt aatatggtaa
     3121 actaggaaca agaagcagaa aggaacgata atcattatga tcaaattaat tgcatcagat
     3181 atggacggca cattattaga tgcccatatg agtgtttctc ctgaaaatgc cgaggcgata
     3241 cgttttgcaa atgatgccgg tgttgagttc atggtcgcta ctggtcgaaa ctatcaagaa
     3301 gctcgcgcag ctttagatga ggtaggaatc gattgtgcga tgatcacttt gaacggggca
     3361 caggtatttg ataaagaagg aaattcattg tttaccgtgt cgattccaaa taatcaagca
     3421 atctctgttt tagatattct agatgctaac ggtatttact atgaagtagc aaccaacgat
     3481 ggtctttatt ctgaaaatca agcgaaacga attgaaagtt ttgcttccat ggtggctacc
     3541 catttacctc accttacgta taaaatggcg attgccatgg cctcagctaa gctggagtta
     3601 ttgcacatca catacgtgga cagtattcgt gctattttgg aagaaaagaa tctggaagtt
     3661 ttaaaaatta tttgttttca tacagaaggg ccagctgtat taggtccagt tggaaagcag
     3721 atttctcttt taggcgatct agccgttact tcctctggtc aaaacaatat cgaagtgaac
     3781 cataaaaacg ctcaaaaagg aattgctgtt gcccatgtcg ctcacgagcg tgggatttct
     3841 ttagaagaag tcatgacgat tggcgataac ttcaatgatg tcagcatgct gcaagtagca
     3901 ggagtcagtt tcgcaatggg aaatgcagaa atcgaagtaa aagattatgc caaatataca
     3961 acggacacaa accttgaatc tggcgtagga aaagccatat tgcgcgcgat tgcagaagac
     4021 ttgtagtttt atctagaaaa gagggatata gatgtcagaa tttttcattc aggaaaagca
     4081 gcttggacgt gcaactcgga caattgtcaa aaacgaaaaa ggacattccc tgtttttgat
     4141 ggttggtcgc tggggaacaa agggcgatgc attgtctctt tatgccatga atggcgatct
     4201 cgttgctcac atcaagcaga taagcctgac attcggtacg cgttttgagc tgtataaaga
     4261 gttcgaaaag gtgggaacca tgcagaaaat attcaattgg cccggtgact tttattatat
     4321 tcgtagactt cactggacag tccaaggtga tatctataat catcaatatc aaatccatca
     4381 tttcaatcag caaatcatga aaatggataa agcaacactt ttttcaggag attactatgt
     4441 attggatgtc tcaaatgatg aagatgctcc agtttgtatt tgtattgctg cggttttaga
     4501 ttactggctc taccgtaaag acaaaagtcg cgataagcct gtttcttacc gacttaactt
     4561 aagttaaaaa gatgtacctg aaatgcggaa atacgcattt caggtacatc tttttagata
     4621 ttcttttgca tatgatcata aagatgacca ctgatcatcc gctgaccgac aactttgaag
     4681 tcatggcgtt cgtataattt tttagccttt ggattttttt catccacact tagaccgatg
     4741 acggagcgat tagctttctt cgccaattta ggtaatgctt ctaataatcg cgaaccgatg
     4801 ccttgtcctc taaaatcttc tgatacactg atagagtcca aataccattc gttgggaaac
     4861 gtttctttat caatgaacaa acgtgtagac gcatctagct gatatttctc taagataggt
     4921 accagtggct gatcgatgat tgattcttct tcatctgtat aaccgtaagc aactcctgca
     4981 actttaccgt ctatttcttc tacgatacct cgtgaataac tgtaacgata atttggatca
     5041 gtgattgctt cttctaaaat ctctaaagtc ttttgttccc ctgtctgctt caaaaatggc
     5101 agttccatat cttttagaat cactaagatc aatggggcga tttctggagc atcttctttt
     5161 ctcgcaaaac gaatcatagt ttcctctcct tttctccatt ctaacatgca gaaaaagaaa
     5221 tcgcaaaatc gttattttaa aaaatcttca atcttttcag taatgaaata accatgagta
     5281 acgattcttg ccgcttcagt tcggcaataa gggcagacga ctggcatttc tttatcatta
     5341 tgttcgacta cattattgac ttcttcgtat gcaaattttt ttccgcaatt agggcatttc
     5401 attttttcca tgttatctca acttcctttc atctttactc tcttagctta ctcttatatt
     5461 gtaaaaaaga gaagcaatat ccttcttcta tgcagatatc catacctgac ggtcctgttc
     5521 tccatctatt aatcggactt tataataagg acgttcatct ttgactagaa gtgtccactc
     5581 tttcactttt gcttttttcc cgtagtagct gactgcttcc ttcatcgctg cttgcggttg
     5641 tttgaactct tccgtttttt ctatatcaaa aagatgttct gcggcctttt ccgtgtcatt
     5701 tcgtacggtt gttttcccag tggatggatt gactgctatg acttgtcctt cacaaaaaaa
     5761 ctggtattca tatgttgcat tcgtaggatt ctccaaatct ttttcaactg caaaatgaat
     5821 agcagatatg ttatgttctt ttgtttcgtt ttttacgatt gctgctgctt ttttcaatga
     5881 gatccgatat tcctggtcac taatatcatc catgtgaaaa gcggcattga gcagtcccgt
     5941 cataccggta atccctatta cgatgagggc agcaacacca aacatcattt ttttcattct
     6001 tcattctcct gtttcttttt tttaaagaat atcaagaaat gaacgaatga aaaatcgaat
     6061 gaaacgaaaa aaaagtgaca attttgttat ctttattcgt gcagttctaa tggcaatccg
     6121 tctggatcaa agaaaaacgt catttttttt cctgtaaagg tatcttctct aatcggttct
     6181 gattcgatcc ctaaggactg caattctgca attgtttctt caatatcgtc tactttgaaa
     6241 gcaagatgac gcaagccaca agcttctgga tagtttggtc gttgtggcgc attagcaatt
     6301 ccaaaaatct ccaattcagc acttcctagt ttcagatcta atttatagtc atctcgttct
     6361 ttgcggtaat tttctctgat tacttcaaat cctaatttat taacataaaa atcacgtgat
     6421 ttctgataat ctgaaacaat gatggctata tgatggatcg ttgtaaggtt catatgagca
     6481 ctcctattct tcgtttaagc tcggatctat attaatctcc agttccattg taaatgtgtc
     6541 agattgaaaa aaatagctgt ttttcctttt tataagaaaa aaggcaaaaa aaacagaaag
     6601 taggtcctcc aagacactct tcctgttccc aatataataa atgaaagtaa gaaattatat
     6661 tttcaagaaa acaaacagaa aattatcata acacaaatta tttataattg aaagactagt
     6721 tttttttcaa gaaaagcata caatagattg tgttagtaaa tacagaacac actacattta
     6781 gtgtcttaag gagtcctcat acatgaagtc atattttcag tttttagctc atcagctaaa
     6841 aggctggccg caacaaaatt attatctttt ctttttcagt cttggctgcc aggtcatgac
     6901 tcttgtcaat agtcccatca cttggctgtc cgttattaca tttatcggta ccacgcttgg
     6961 tgtattgtgt attttatcca tcaatgcggc aaaatcagtc aacggtattt taggtatttt
     7021 gtctgcgatt tgttttatta tcgttgggtt ttcagcaaag aactatttaa gtatcggtga
     7081 acagattgct tatatgatca cattggatat ccccgtattg ttaagtaaag aatggaatca
     7141 taatatggct tcaaaaatcc gaaaattcac tggaaaaagc tggtttatcg caatcatcag
     7201 tactttcctt gtctatcttg tttcaggatt cctgattggt cgttatacag atgatcctcg
     7261 gccgtgggta gatgccattg ctttttctat tagcttgact gctggtatca tcagtttctt
     7321 gcgttacaac aaccaatatt actggtggtt agcttcaggg cttgctcaaa tggtcctttg
     7381 gtatatttca tttacgcatg gatctgcaag tttggcgatg ttcgtgaaca gctctgttta
     7441 cttgctgaat gatgtccttg catttaccgt ttcaccttgg tataaccaaa aagaacgtga
     7501 acgtatgcaa aaaatggaag aagaatacta caacgcacaa caacacgcat aaaaaaactg
     7561 agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta taaacggcgg
     7621 aatcagaagc aactccttcg gaaataagct gaaattcaca aaaatttgaa aagcaatttt
     7681 cgtgaatttc ttcttatttc ttggagttaa acgcttctgt cccagcctct atttcctacg
     7741 attagtcaag taaaaggtgc aagaaaaata gctcgtaaac gaaagcgaca aaatcaa
//
LOCUS       DADGKS010000108         7760 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.113, whole genome shotgun sequence.
ACCESSION   DADGKS010000108 DADGKS010000000
VERSION     DADGKS010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7760
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.113"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(552..1898)
                     /gene="gor"
                     /locus_tag="JXV47_002645"
     CDS             complement(552..1898)
                     /gene="gor"
                     /locus_tag="JXV47_002645"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HAX1488648.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(2032..3273)
                     /locus_tag="JXV47_002646"
     CDS             complement(2032..3273)
                     /locus_tag="JXV47_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAX1488649.1"
                     /translation="MTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAYGLRS
                     RAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISAVIVS
                     DPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVAEIRK
                     NTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFGQERN
                     SLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNVYKAA
                     VDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVYKFVG
                     EVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRAPNPM
                     MILTMPVAQPVKPGDMIRKRK"
     gene            complement(3291..4214)
                     /locus_tag="JXV47_002647"
     CDS             complement(3291..4214)
                     /locus_tag="JXV47_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAX1488650.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(4435..6927)
                     /locus_tag="JXV47_002648"
     CDS             complement(4435..6927)
                     /locus_tag="JXV47_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HAX1488651.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(6934..7401)
                     /locus_tag="JXV47_002649"
     CDS             complement(6934..7401)
                     /locus_tag="JXV47_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HAX1488652.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(7537..7610)
                     /locus_tag="JXV47_002650"
     tRNA            complement(7537..7610)
                     /locus_tag="JXV47_002650"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7574..7576),aa:Arg,seq:acg)
     gene            complement(7668..7741)
                     /locus_tag="JXV47_002651"
     tRNA            complement(7668..7741)
                     /locus_tag="JXV47_002651"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7705..7707),aa:Pro,seq:tgg)
BASE COUNT         2161 a         1691 c         1247 g         2661 t
ORIGIN      
        1 aaatcagtgt tttgtcctga gtattagaga aacaaatgga aaaatagttc ctcatatttt
       61 gccgtttttt gagctaatac cgaaggacag ctgattgaac actatttgtt cggaaaaagt
      121 gactaactat gacacaattt ttttcacagt cccttttttc acttgatttg attcgtacca
      181 gcgaacttga cgagaacttt cttggtttgg taactatatg gtattctttt aacatcctcg
      241 tttgcttctt ctaatttatt tatacaaagt cacacttttt taaacatctg ttcttcgata
      301 catttctatt tcttttaaac atcgatacca atattttgaa cttaagagtg cataccaaat
      361 ggattcattt actcttcgtc agttacgaag ataatcaaaa tctccaactt ccctacttat
      421 ttcgttttga gaattatcga agcaatctta cataaataac taaaaaacaa aaaaccagaa
      481 aatcagtata ctgattttct ggttttacat ggtttgttca ataaaaagct gttggaactg
      541 ttaatattaa attatcgcat cgttacgaat tcttccgctc ctgttggatg gatggctact
      601 gtattgtcaa agtcttcttt agttgcaccc atcttgatag ccacggcaaa accttgcagc
      661 atctcatcga caccaacacc aatagcatgt aagccgacga ttctttcttc ttttccgaca
      721 cagatcaatt tcatttcgca tttttggcga taatcattta atgcaaagta cattggggta
      781 aagcgtgaac gataaacttt caattcattt tcgccatatt tttccaatgc ttcttcttct
      841 gtcaaaccaa ttgttgcaat tggtggatgc gtaaagacga ctgtcggaac aagtttatag
      901 tcaagataag aatctttctt tccattaaat aaacgttctg ataaacgtct accagctgcg
      961 attgcaacag gagtcagatc taatttaccg atcacatcac caacagcaaa aatatgttca
     1021 tccgttgtat tttggtattt atctactttg ataaaccctt ttttgtccaa ttccacattt
     1081 gtattttcca gacctaattt ttcggtattc ggtacacgtc caccggcaaa aagtacacaa
     1141 tcaccagtta aggtttcacc attttcaaat agcaccgtat attcgtcatt gtttttagta
     1201 atttctttag caatatgatg tgcgtaagtt tttattccag cttcttggta catttggatc
     1261 aaattgtccg aaagcatttt atcaaacgtt ctaagtggtc gttcttttcg atatgcccac
     1321 atgacttcac tacctaaacc acgaaataca cctgaaagtt cagccgcaat gtatccagca
     1381 cctaaaacga ttgctctctt aggtaactct gttaattcaa aaaatccatt tgaatcaatt
     1441 gcgtattctc caccaggaat ggtcatttta cttgcacggc ctccagtagc gatcaagatt
     1501 ttaggagcac gataggtttc accgtttact tcgatcgttt gactatcgat aaaagtagcg
     1561 taacctttta tagcctcgac atgattgcta tctaatcctc tttgataagc accgtgtaga
     1621 aaatcaatat atttttctcg tctttctact agaccggcga aatcaacatt ttttaaatct
     1681 gcttggatac cgtaacttga ggcatctcgt tcaattgttt ccaaaatcgt acttgcttgc
     1741 cacataactt ttttaggtac acaaccgacg ttgacacatg ttccgcccaa ttcattcgct
     1801 tcaatcagca aaacttttgc gccatgcatc cctgctctgt ttgctgaagc aataccgcca
     1861 gagccgccac caattacgat gtaatcatat atttgcattt tgttcctcct tattgaagag
     1921 atcaatcaaa acctttattt aacgatcctt tttctacaga aaacaagtgt aacacttttc
     1981 ttgaattttg tatgcgaaga tgcttaaaac agggatatat cagctttttc cttatttacg
     2041 ttttcggatc atatctccag gtttcaccgg ctgtgcgact ggcatagtta aaatcatcat
     2101 tggatttggt gctcggtcaa tggattcgcc ttcttcatta tgcataactt caacggtttg
     2161 actgaaatga ctgaatcctg gaccataaaa ttcgatttca tctcctacag aaaacaagtt
     2221 tctctgacgt atcgtagcaa tctgtgttgc ctcatcataa gataatactt caccgacaaa
     2281 tttatatact gggattttac gacgttcacc gaataattgt tcgttttcag ttggtgtatt
     2341 gtagtaaaaa cctgtagcta attctcgttg tgctactttc cataactcgt cgatccattc
     2401 ttgcttgcag acatagtttt caggatcttc catataactg tctacagccg ctttatagac
     2461 atttgacacc gtagatacat aatggatcga tttcattctt ccttcgatct tgaagctgtc
     2521 tacgccgttt tcaatcaatt ctggaatatg ttcgatcatt gacatatcca ctgcactcat
     2581 cgagaattct tcttccactt cgcctgtatc agttaaactg tttcgttctt gaccaaaagg
     2641 catatcgaac aatccatact tccagcgaca agattgagaa catccgccac ggtttgcatc
     2701 ccgcatcgac atatggttgg acaatgtgca tcgaccagaa taagagatac acatggcacc
     2761 atggataaat gcttcgattt cggtatccgt atttttacga atctctgcca cttcctccat
     2821 tgaaacttca cgagctaaaa cgacacgttc caacccttct tctttccaga attccaatgt
     2881 ctcaaaatta gttgctgaag cttgagtgga taaatggatc ggcagacctg gggcttctgt
     2941 cgcacaaatt tcgatcaaag ctggatcaga aacaatcact gcagaaatac cgacatcacg
     3001 caaactgcgg aaaaattccc ctgctccatc ttcatttcct tcatgggtga ccatattagc
     3061 agcaacgtat accttcgcat catgttcttt tgcaaaagca actccttcag ccatttcttc
     3121 ataagtaaaa ttacctgcac ggcttcttaa accatatgca ttcccgccaa tatatactgc
     3181 atctgctcca taatggatcg cggtttttaa cttttccagt gttcctgctg gcgctaggat
     3241 ttctggtcgt ttcaattttc tttttactgt catttctttc atcatactcc ttatttgata
     3301 gcagaaggat caatataaaa gaatcctgta tctaattcac ggttttcagg atgcaattta
     3361 ctgatttcgc tagtcatttt ttccgctttt tcttgatccc agctaccttc taaaatttgt
     3421 ttttttgctt cggcgaatag tcgagtgatg tttacgaatt tttcgcctgg agtaaataat
     3481 ccgtccaatt tccatgtaca gtaatgatgc tgataaagtt cattcaattc attcgagaga
     3541 ttcagatcat tgctggcaaa aatatgtgtg ccatgactat cttcataaat agaataatgt
     3601 gtctcttctt ttttaggttc cgagataaaa agacctcttt cacgatcttt ttgttcgtct
     3661 tgtttcgtat agttatagta attctgtagc agtggacgtt tggattgatg gatgcatgta
     3721 gcaccataca caagggtttc tacaggaata tcgagttttt cttccatcgc cttcatctct
     3781 tcaaaaggaa cttcacgagc aagtactgct ccaactgcgc cttttttcgc ccagaaattg
     3841 atttgacgtg cgctcgttac taatgtttca gcatcataaa tatacggtat acgcaattca
     3901 ggattttttt tcatcgtata aataatacct gtatcaccaa ctgtgatcac atctacgttt
     3961 atttctttta aaaaagccaa atattcaggt acatttttca ttttttcagg atgaatgatc
     4021 ccatttacag caatattcgc ttttttacca tacttgtgtg ctaattctac caattgtcgc
     4081 tgttcttctc gtgtaaatga agcaggcaga cgcaatccaa attgctcttc accgaaatat
     4141 agtgtatctg cacctgcagc aagcaactgt tctgcttgtt caatagtttc tactgtggtt
     4201 atgagttcga tcataatttt ctcctcctac aacttcataa tagtagcata gctctaaaaa
     4261 ctttccaata cttcttctat ttaaagtcgg atttttgaaa attatttcac aaaaaatcaa
     4321 aataaagttc gatatattct gtccaaatat aaaaagagat tgtgacaaaa atcttgtcac
     4381 aacctcttaa tcaagtctta ctattataaa aattcagcta cacaggccaa gtaactatag
     4441 ggaacctact gtttcctttt taggtccgcg aacattcaat gtgatcttac cttttgaagc
     4501 acctactgtt acgtggtcac ctaaacgaat ttctccgcca agcaaagcct cgctcaatcg
     4561 atcttcaatt tctttttgaa gtgcgcgacg gattggacgt gcaccatatt caggatcaaa
     4621 tccagctttc ccgatcacat cgattgcaga tggtgtgatt ttcacttgaa tatcttgttc
     4681 tttcaatcgt ttgataatcg ctttgctcat gatttggacg attgtatgga tttcatcttt
     4741 actcaatgaa tggaagacga cagtctcatc gattcgattc aagaattcag gtcggaaagc
     4801 tttctttaac tcttctaaga tacgtttttg catggctttg tgatctttag taacatcttg
     4861 gacattgaat ccgacatttt tttcttctcg aatttgtgtc gctccgatat ttgaagtcat
     4921 aatcatgatt gtatttctaa agtccacttt tctaccttta gaatctgtta aatgaccatc
     4981 atccaatact tgcagaagta aattgaaaac gtctggatgt gctttctcca cttcatctaa
     5041 gagaatcact gaatatggtt tttgacgaat tttttctgtc aactgtccac cttcatcata
     5101 ccctacgtat cctggaggag acccgattaa tcggcttgta ctgtattttt ccataaattc
     5161 tgacatatca acacggatca gggcatcttc acttccaaac atgacttctg aaagtgcttt
     5221 ggccaattct gtttttccga caccagttgg tccaaggaac atgaatgaac caattggacg
     5281 atcaggatct ttcaatccgc ttcgtgcacg gcggatcgca cgtgaaactg ctttgacagc
     5341 ctcatcttga ccaacgacac gttcatgcag aagtccttcc agttctaaca agcgttcgct
     5401 ttcttttttc tccaactgct gtagagggac accagtccac tccgatacaa ctgtagcaac
     5461 atcttcttct gttacacgat cagaataacc ttgctcctgt tttgcttcaa ttgcagaaac
     5521 tttttgcagc tttttacgta gtgctttttc ttgtctgcgt aattgagcag cattttcaaa
     5581 gtcttgtttt tggatcgctg cttccttttc ttgtactagt tcatcgattt ctagtttgat
     5641 cacagttgat tttgttaagt gatcggtttg atccaaacgg actttcgctg ctgattcatc
     5701 gatcaaatca attgctttat cgggtagttg acgagaagtg atataacgaa cagaaagatt
     5761 gactgctgct cgtacagctt catctgtgat ctccactcca tggtgctctt catatcttgt
     5821 acgtaatcct tgaagaatca cttctgcttc ttcaggagtt ggctcatcta cttgaatgcg
     5881 agcaaaacgt cgctctaatg cagaatcttt ttcgatatat ttttgatatt catctagggt
     5941 cgttgctccg atcgtttgta attctcctcg agctaacgcc ggtttcaaga tattcgaagc
     6001 atcaattgct ccttctgctc cacctgcacc aattaaggta tgcaattcat caatgaataa
     6061 gattacttga ccatcattat agatttcgtc gatgaccttt ttcattcgat cttcaaattc
     6121 accgcgatat ttcgtaccag caaccaaaga tcccatatca agcatcatca ggcgcttttc
     6181 ttgcatgtct tctggcactt cacctaaaat gattttttga gctaaccctt cagcaatggc
     6241 tgttttgcct acaccaggtt cacccaccag tacagggtta ttctttgtcc gtcggctaag
     6301 aatctggata agccgtttca cttctctcga acgaccaaca actgggtcca gcttgttttc
     6361 ttttgctaat ttcgtcaaat cacgtgctaa tgaatctagc gtaggtgttc cttgcggtgt
     6421 ttgccgttta tcttgtacat ttacatttct acgacgattc attccttttc cagcagaatc
     6481 accagctagc cccatttttt gtttcagaac ttgacgggct tttgaaaggc tgatacctaa
     6541 gttgatcatg attcgagtag ccatgatact ttcatctttt aataagctca tcaaaatatg
     6601 ttctgttcca actttttgag aaccagtttt cttcacttcg ctgctagcta aagcaaaaac
     6661 ttgtttcatt cttggtgaat atggaagaaa gactccttta gggtaagaac ggataccacc
     6721 ataaccaatc agatgttcaa tttcttcata aatttccgtt tcattcaaat ccatttcacg
     6781 taatactttt ccagcaattc cattttgctc gaccactaag gctagtaaaa catgttctga
     6841 actaactgat tgatgtttca accgttttgc ttcttcttgt gcaatttcta atactgcttg
     6901 ggctctttca gtaaaaagtt cttccatcta atctcacttc ccatcttcat aacttaaacg
     6961 ttccagaaat gctcggagaa tccgagcacg tgtatgatct tcatattcat tgaaattcaa
     7021 tgtgtttttt gcaattgcac tcaacatcaa gtttccttct ttttttgtaa ttatttggtc
     7081 ttcataaagt ttttgaataa tagcaaaagc atttttctca ctgattgtat catcaaataa
     7141 ctgatttatc tgctcaagta attgtttttt atctgaaatc cttacttttg caattcgtat
     7201 ataaccacca ccaccacgtt tgctttctac tagataacca cgttggatgg taaaacgggt
     7261 attaatcaca tagttgattt gtgaaggaac acagttaaag aggtctgcca tttcaatcct
     7321 tcgaatctcg atcatttcac tattttccag aattttcttt atatatgatt caattaaatc
     7381 cgaggtattc tgatgtgcca tcttattcat tccctttgac taatattgac cttaattata
     7441 acgaatttga taatagaaag aaagaagaac gctttttgtt aaataaatcc tttagaatca
     7501 acaaaaaaaa atacggaata tactattccg tatcgacgcg cccaagagga gtcgaacccc
     7561 taaccttttg atccgtagtc aaacactcta tccagttgag ctatgggcgc atattcaatt
     7621 taaaaaaatt ataaatcatt tgaaaacaaa aagcaagata aaaaaaatcg ggaagacagg
     7681 attcgaacct gcgacccctt ggtcccaaac caagtgctct accaagctga gctacttccc
     7741 gtttaaaaaa taaaaaagac
//
LOCUS       DADGKS010000109         7630 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.114, whole genome shotgun sequence.
ACCESSION   DADGKS010000109 DADGKS010000000
VERSION     DADGKS010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7630
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.114"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..548
                     /gene="prs"
                     /locus_tag="JXV47_002652"
     CDS             <1..548
                     /gene="prs"
                     /locus_tag="JXV47_002652"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAX1488653.1"
                     /translation="FFDIPVDHLMGAPLIANYFLEKGIKGDDVVVVSPDHGGVTRARK
                     LAEFLKSPIAIIDKRRPKANVAEVMNIIGQVKGKTCVLIDDMIDTAGTITLAANALKE
                     AGATSVYASCTHPVLSGPALQRIEDSAIERLVVTDSIYLPEDRKIDKIDEVSIGGLMG
                     DAIKRIHENKPVSPLFETKNK"
     regulatory      554..656
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            722..1291
                     /gene="thiT"
                     /locus_tag="JXV47_002653"
     CDS             722..1291
                     /gene="thiT"
                     /locus_tag="JXV47_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HAX1488654.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     gene            complement(1372..1659)
                     /locus_tag="JXV47_002654"
                     /pseudo
     CDS             complement(1372..1659)
                     /locus_tag="JXV47_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1765..2844
                     /locus_tag="JXV47_002655"
     CDS             1765..2844
                     /locus_tag="JXV47_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006908283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAX1488655.1"
                     /translation="MTQNHDNTVSRKGKHLTYSERCQIAILKKENYSNRQVADVLGCV
                     PQTINNEIKRGTVTQLNRQNQNGKVYDYYHDVYDADAGQAAYEKNRLNCGRRPLWADT
                     DAFIEWADDMMLLEKWSPDVVVGFARKHELFDPAIIPGTTTLYQWIDRGIMKTKNMDL
                     LEKLSRKPKSSRHGNRPNKRVLGKSIEERPEAVGTRKTFGHWEVDTVVGNKTKSDAVL
                     LTLVERQTRFEVILKLAGKDAESVNQAVRQLRERAGAYFGQLFKTVTSDNGSEFAGLH
                     DALQDVANIYFSHPYASWERGTSENQHKLIRRFIPKGSPIGNVSENQILRIQRWMNDY
                     PRKILGYATPHDTFVQAFRQERLTA"
     gene            complement(3037..3534)
                     /locus_tag="JXV47_002656"
                     /pseudo
     CDS             complement(3037..3534)
                     /locus_tag="JXV47_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734092.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3801..5501
                     /locus_tag="JXV47_002657"
     CDS             3801..5501
                     /locus_tag="JXV47_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HAX1488656.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            5471..5689
                     /locus_tag="JXV47_002658"
     CDS             5471..5689
                     /locus_tag="JXV47_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488657.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            5709..6599
                     /locus_tag="JXV47_002659"
     CDS             5709..6599
                     /locus_tag="JXV47_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HAX1488658.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            6617..6901
                     /locus_tag="JXV47_002660"
     CDS             6617..6901
                     /locus_tag="JXV47_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488659.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            7388..>7630
                     /locus_tag="JXV47_002661"
     CDS             7388..>7630
                     /locus_tag="JXV47_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HAX1488660.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNY"
BASE COUNT         2473 a         1414 c         1664 g         2079 t
ORIGIN      
        1 gtttctttga tattccagtc gatcatttga tgggtgcgcc acttattgcc aattatttct
       61 tagaaaaagg aatcaaaggc gatgatgttg tcgttgtttc accagaccat ggtggtgtca
      121 cacgggcacg taaattagcg gaatttttga aatctccgat tgcgatcata gacaaacgcc
      181 gtccaaaagc aaatgttgca gaagtaatga atatcattgg acaagtcaaa ggcaaaactt
      241 gtgtactgat cgatgatatg atcgatacag caggtacgat cacattggct gccaatgctt
      301 tgaaagaagc tggtgcaact agtgtgtatg cttcatgtac acatccagta ttatccggcc
      361 ctgctttaca aagaatagaa gattcagcta tcgagcgtct agttgttaca gactcgatct
      421 atcttccaga agatcgtaaa atcgacaaaa tcgatgaagt aagtattggc ggactaatgg
      481 gagatgcaat caaacgtatc catgaaaaca aaccagttag tccattgttt gaaacaaaaa
      541 ataaataata aataaactca caaaggggag tccaattggg ctgagattga atctatttct
      601 aaacccttcg tacctgtatc ggttatgcga gcgtaggaat tgtgaataaa cagctgtttg
      661 actattttcg aaagctgctt cctcctttgt gactttttta ttcaaaggag gaagtttttt
      721 tatgggaaaa aatagagttt gggtagaagg aacgattgtt gcagcgttag cgatggtgtt
      781 gtcgttgatt ccgatccaga tcggcagcag tttttctatt tcattagggc agattccatt
      841 gactcttttt gcgttaagaa gagggacaaa ggcagggatg ctggcaggtt tcatttgggg
      901 catcctacat tttccgttgg gacaagttta ttatttaagt gtcgttcaag tgttgattga
      961 gtacccgatt gcctatactt ttgcaggcgc agcagggctc atggcttcaa atgtccaaaa
     1021 aggctatgta gacgataata cgaaacaaat tagaaaaagc atcgtgtttg gtgcattgat
     1081 tggcgcactt tccagatatt tttggcattt tattgcagga gtggttttct ggggagcgta
     1141 tgcactatgg gggatgaatc cttggctctt ttctttcgta atgaatggtg ccagcgggtt
     1201 gagtacagct attgtaacga tcatcgtttt attagggatc caacaaacga ctccttcgat
     1261 ttttgtgcca gataaacgac aggagctgta aataaaaaag aagcaagaaa cttgagacag
     1321 aatcatgtcc tagtttcttg tttccttttt attttttgat aagaaataga tctacttcaa
     1381 tggcagataa gaaagatcgg catcttctac caattgccag tgtcgatcgg tgacagagta
     1441 gattaaagta gcgatgattt cctcttctcg ataccgggtg ccttttaatt tccaaatata
     1501 atcttcaatc acatagattg ggatacgata tttaccatcg atcaaaccaa cttgatcaaa
     1561 agaaaaaatg atcccttcct gcatcaaatt acgcatttct ttcaataatt ccacactgat
     1621 tttttcaaca ggtgtttctt ttttgaaaaa agatttttgg cggattttat aattaactta
     1681 gccatttgga aataaaaaaa cgccacgtga attccatgtt atattgaagt taccacaact
     1741 ctcaatagac aaggatgaat tcacatgacg caaaaccatg ataacacagt ttcacgcaag
     1801 ggaaaacacc taacctactc agaacgttgc caaatcgcca tcctgaaaaa ggaaaactat
     1861 tccaaccgtc aggttgcgga tgtcctgggc tgcgtgccgc agaccataaa caacgaaatc
     1921 aaacgcggga ccgttactca gcttaaccgc cagaatcaga acgggaaggt ctacgactat
     1981 tatcatgacg tctacgacgc cgatgccggg caggcggcct acgagaagaa ccgcttgaac
     2041 tgcggcagac ggcccttatg ggccgacacg gacgccttca ttgaatgggc ggacgacatg
     2101 atgctgttgg aaaaatggtc cccggacgtg gtggtgggct ttgccagaaa acacgaattg
     2161 ttcgacccgg ccattatccc tgggaccacc accctctatc agtggatcga ccgtggcatc
     2221 atgaaaacga agaatatgga cctgctagaa aaactgtccc gcaaaccgaa atcgtcccgt
     2281 catggcaacc gcccgaataa acgggtgcta gggaaatcca ttgaagagcg cccggaggcg
     2341 gttggtaccc ggaaaacctt cggccattgg gaagtcgaca cggtcgtagg aaacaagacc
     2401 aagtcggatg ccgtgctgct gacgttggtg gaacggcaga cacgcttcga ggtcattctg
     2461 aagctggccg ggaaggatgc cgaatcggtc aaccaagcgg tccgacagct gagagaacgg
     2521 gctggtgcgt acttcggcca gctgttcaag acggttacct cggacaacgg ctcggagttc
     2581 gcgggactgc acgatgcctt gcaggatgtg gcaaacatct acttcagcca cccctatgct
     2641 tcctgggagc gcgggacgag cgaaaaccaa cacaagctga ttcgccgttt catccccaag
     2701 ggcagcccaa tcggcaacgt gagcgaaaac caaatcttgc ggattcagcg ttggatgaac
     2761 gattacccgc gaaagatttt gggctatgca acgccgcatg acacgttcgt ccaggcattt
     2821 aggcaggaac ggttgacggc ttgacacgtg ggcccttgac aacgagcctc cctcggcatg
     2881 gcttgtgtct ggaaagctgg ccggggccag ccagtcggga gactaccatg cctcagctca
     2941 ttgtcaaggg cccactcgat tagaaaaatt agacggttgg tggtaacgag caaccgggtc
     3001 accatgggtg gctaacttaa acttgaaatt tacgaaaaaa gattttttta cattgatctt
     3061 atctgacaag atcgaactta atttactagc aaaaatccta taaaattcat ctaaatagcg
     3121 ataataaatc cgattcagct gatcattaag atcgaagtat acaaaattat tctgtagttt
     3181 ataaaaaaac ggcgaatgaa gatgtgtttt catatgacca aaatataata attctgaaat
     3241 ttctaaaggt gtcaattctt tcagcatcgt taaatcagta aagtcgatcc acttcaattc
     3301 atcgaatcca cgcctgttac gagaagagga aaagaaacgc tgaatatttt ctgtaccacg
     3361 gattactttc agccctgtat gggattcata ttctccagca gaagcagatg gatcaagcaa
     3421 gagcaagttt tgaggaaaat gcacgatact gtttgcaaag tcagtagcag tcagcccttt
     3481 tgttaaaaca gcattacttg tggtatcaat atgtacataa actgactcag tcatcatgtt
     3541 cctcctctta tttcctctta atctctttta ttttacaaca tttgcattaa aaaagcttgt
     3601 ttcttttatt ttaaaattcc attacaaaat cacgttttca ttaaaaacac tctcattttc
     3661 aattaatttt tgtgattttt gtattttttt atttaaagga ggttttatga attgttttct
     3721 tatggaatct acaaagtcga atacgagact catgaccttt ttatgacgta ctggtatact
     3781 tgaagaaaaa ggagagcgcg atggagataa aaaaagttta cttttcacag aaaatgtcgc
     3841 tgtattcgcc tatccagcaa gcaaaacaac cccttccatt ttttcaaagt catcaagaaa
     3901 gtagagacgc tttttggcgt tctgcaaaaa agcaatgtgc ttttaaagca gtatcgaaaa
     3961 aatataccgt ctattttact attgctaaaa gtagaggaga tgttattttt aataatctgt
     4021 tgattgaagg tgaaactttt gaatggaaaa aattttttcg gtatatggaa gcttgcgctc
     4081 gtttttttat taaagaaaac tgttgttttt tatttcaatc tcctctatca gaagaatggt
     4141 tgcgtatttt tcataaaaac ggctatcaag gaaccacaca attaaataaa aagctggtct
     4201 atcatacagc acttgtttta ggtggaggag gagcgcacgg tgcttatcag attggtgtgt
     4261 ggcaggcgct gaaggaacat gatatcaact ttgagattat cacaggtacc tcggtaggtg
     4321 cgttgaacgg cgcattgatt ttacaaggag atatgaaaaa agctgtgaat ttatggaaaa
     4381 agctgtcgac aagacaagtg cttgcgttac cagaaatggc tgcagttgaa gaccttcgtg
     4441 aacgcttcta tcgagaaaga cgccaaatga cgaaaacagc actaattgaa ggcggggttt
     4501 cttctgctcc attggaaaag atggtcaaag acaatttgga tttgtcctta ctcaaacata
     4561 atcccaaaat acgtttatat acggtgtcta ctaaactgcc agaactagcg gaagtagtga
     4621 ctgatatcca acagacaaaa acagaagaaa taccagattg gatactcgcc tctgcttcat
     4681 tttatcccgc tatggcttat cgaaagatcg gaaaaaataa atatgcagac ggtgggtatc
     4741 gcaacaaaat acctattgat attgcgatta acaaaggagc aacagaggca tttgtcgtag
     4801 atgtgcaagg gccaggccca gcgaaaaaaa ttcgtatgcc agacattttt atccattgga
     4861 aatgtcaaac attgtggaca ctaggcagct ttctgctttt tgatagccaa aggaaccaat
     4921 taaatttaca attaggctat ctggaaatga aaaaacgatt aggctattac tatgggaact
     4981 ggtatacatt tcattctgtt aaacctgcaa gaacatactg gcgaggattt ttgtcttact
     5041 taacaaaaga aattcagtta gaattatctt ttttcaaaag cataaaattt tggcaaaaac
     5101 tgcgtaattt atataagaac agggtcgtac cagagacatg cggattggcg atgctagaac
     5161 ttttagcaaa aaaacatttt ttactgccca atgaaatcta tcaagtagac atgatgattc
     5221 aaatgatctg ccaacaagat ataaaaagta tgccggatga tttattggca caaattggtc
     5281 aattaagtac tgaagaatgg cgaaggtatc gaaaatacca gcaaaaaata caaaatgagc
     5341 gcacgaaaac tgtttatttt gattatctgc tacaaggaaa acgcaaggat cgtttgcagc
     5401 atgaattgct taagcaacca gttgacacat tactgatcct atatttatat tatctcaagg
     5461 aggaacaacc atggcacaag aattttcata tgaaatcgta gaagaaatcg ctatattgtc
     5521 agaaaacaac aaggggtggc gtaaagaact gaacctagtc agctggaatg gtcgcccgcc
     5581 aaaattcgat cttcgagatt gggcgccaga ccatgaaaaa atggggaaag gcctgacatt
     5641 gacgaacgaa gagtttgaac aactgcaaaa agcaatagaa aatatgtaat gaggaaggac
     5701 cctgtcgaat gaaaagtatg actggttttg gcaaagccat ccgcgaaaca aaagcgtatc
     5761 agttagatat tgaaataaaa agtgtcaacc agcgttttct agatgttcaa atacgaagtc
     5821 ctaaaatcct gaactttgtt gaaaacgatt ttcgtcagct tattaaacag cagttaagcc
     5881 gcggtcgaat cgaagtattt gtgaatctag cttatattgg caaaaacgaa aaacagatcg
     5941 tcatcaactg ggaattgatt gattcactta tcactcaatt gacagacgga attcaacaac
     6001 gatacggtag tcaaaatcaa gtgtcaatta gtcggatggc ggaacgcttc gcgctggacg
     6061 aaaacttcgt aacggtagaa gaaaaaccgg aagagagcat ggaagaattg gcacagttag
     6121 ctctagatac attgaaaagc gcacttgatt ctattgaggc gagtcgagaa aaagaaggtc
     6181 aagctttagc tttagtgttg aaaaagaata ctgaagaatt caaagaagta ctaaaaaaac
     6241 tcgatagttt tgtagaaatc tatgaaaagg aatttcaaat aaggtatcaa aaaaagctgg
     6301 aggaatttct tggagcgaaa gtcgatgagc aacggttgtt gacggagcta gccatcttgt
     6361 tggaacgcgg agatattcac gaggaactgg atcgtctggc gatccatgta caaaaactag
     6421 atgaacttat cgaagcacaa tgtcctgtag gtcgggaatt agatttcctg atccaagaaa
     6481 tgaatcggga aatcaacacg atcggttcca aatcaaatgc aatcgaaatt aaaaatcaag
     6541 tcgtccagtc taagacgatc ttagaaaaaa tcagagaaca agtacaaaat attgaatgac
     6601 gaaagaggta gagataatga aatattatga cgtaacgttc cacgaattaa gtggaaaaac
     6661 tgtggttaaa cgggatatcc cttctgaaaa aaacggcttt gacgtatgga aagatgcctg
     6721 tgcagactat aatgagaacg aactgtttat tttgatcaac gacggtgctt acgtgacgat
     6781 gaatcggaaa tttattgttc gaattgacac agaagaggta gaagatccga cagaaaaagc
     6841 acgttctcga aaagatgaga tcatgggtgt agtgaatact ttgtccaata tgggctttta
     6901 gcaaggatgc tgaacaaaga aatacaataa ataatcagaa ttggatttct tcgcttagct
     6961 tctttgctct aggaatacat ttaaaggttg tgacaaaatt cgtgtcacaa tcttttttta
     7021 ttttgaataa gtgatgttca aaaaccattt tctcggtatt aagccaaatt tatgcaaaaa
     7081 tgtgagaaac tattttcaca aaatttttct tcatactcga aactaatcgg cttcttcacg
     7141 acctcttata cacggcgttc aaaagcttgc atctgcgata ataaccccaa ccaaacgaaa
     7201 aacatgagaa gctgtttatg tttggctgtt cttattactt gatgcaggac agctttttta
     7261 cgacctcttg gtacagggta gcttttttac caatttctag ctataattaa agataacctt
     7321 gaaagttgca gaaaaaaagt gcaaaataaa cgataagtac aaaaagacta gttgaaagga
     7381 cgtcgtcatg tcagagcgtg gattattaat cgtgttgtct ggtccatccg gtgtaggaaa
     7441 aggcacagta cgaaaagcaa tttttgagag tgaggataat gattttcagt attcgatctc
     7501 aatgactacc cgtaaaatgc gtgaagggga ggtcgaaggc gttgattatt tcttccgaag
     7561 caaagaagag tttgaatcaa tgatcgaagc tggagagatg ctggaatacg cagaatatgt
     7621 cgggaattat
//
LOCUS       DADGKS010000110         7599 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.115, whole genome shotgun sequence.
ACCESSION   DADGKS010000110 DADGKS010000000
VERSION     DADGKS010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7599
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.115"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(137..427)
                     /locus_tag="JXV47_002662"
     CDS             complement(137..427)
                     /locus_tag="JXV47_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488661.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(545..805)
                     /locus_tag="JXV47_002663"
     CDS             complement(545..805)
                     /locus_tag="JXV47_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488662.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(942..1355)
                     /locus_tag="JXV47_002664"
     CDS             complement(942..1355)
                     /locus_tag="JXV47_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HAX1488663.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1811..2296)
                     /locus_tag="JXV47_002665"
     CDS             complement(1811..2296)
                     /locus_tag="JXV47_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488664.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2435..2650)
                     /locus_tag="JXV47_002666"
     CDS             complement(2435..2650)
                     /locus_tag="JXV47_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HAX1488665.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2874..3674
                     /locus_tag="JXV47_002667"
     CDS             2874..3674
                     /locus_tag="JXV47_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAX1488666.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3693..5561
                     /locus_tag="JXV47_002668"
     CDS             3693..5561
                     /locus_tag="JXV47_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAX1488667.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5554..6045
                     /locus_tag="JXV47_002669"
     CDS             5554..6045
                     /locus_tag="JXV47_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HAX1488668.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6033..6587
                     /gene="srlA"
                     /locus_tag="JXV47_002670"
     CDS             6033..6587
                     /gene="srlA"
                     /locus_tag="JXV47_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174078.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HAX1488669.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6605..>7599
                     /locus_tag="JXV47_002671"
     CDS             6605..>7599
                     /locus_tag="JXV47_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HAX1488670.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1213 c         1443 g         2236 t
ORIGIN      
        1 ttgttactat gaataacata ataagaaagt aaagtggatt gatttgagat ctttttatac
       61 ttcaaaaaag ataacaccca actttcaaaa atatgttttg gaagttggga caaacgagtt
      121 aatacatttt aatacattat tttttattca aaaaaaatag cacaatggca aagatcgtaa
      181 gagagatcat aagccccaat gaatgactaa aaagaaaagc agaatcacat gccatatcat
      241 cccatatttc ttcaagaaaa taaataagcg ggaaaaaggg aaggaatagt agaacatcga
      301 tccagcacca tttttttctt cttttgaaat aacataaaac aataaacatg aacgtgcagg
      361 gaagtaaaaa caaagcttta ctcataacta acaaaatacc agctcctttt atttttttct
      421 cccccacatt caaagagtaa caatggtatg tacttaataa tagaaaaatg gatcaacttg
      481 tatgaataac agctgaaaag atctgcacca aataaaaaac ttccagccaa aactgactgg
      541 aagtttattt ttttctgaaa tattctaaca caaatatgaa aaagatggcc gaagctaata
      601 agccgatttc gtagcaaaac aatgagatac cagagtcgta ataataaaat cctctaatct
      661 tatggataaa atagatcatc ggacaagcag ataagagtaa gtatttgtta ggccttttga
      721 ataagtaaaa gaaagcactg gtcattatga taaatggtat ccaaaacaaa agtttactta
      781 agacaatcaa atgatcaact cccatatttt ttaccaagag agatcataac atctttatcg
      841 taaaaacaaa atattttttt gctcattttg aaaatttaaa catactcgtt cttatccaaa
      901 tatataaaaa tcgcccctca ttcatcgaga ggcgataagt tctaatttaa ctcaattttt
      961 tttgtttctt ttggctgata agctgtttta ggtaatacca atttcagcac accgttttta
     1021 aaggttccag tgattttttc ttcatcaaca ttaggaagat agaatgaacg tttgtaagag
     1081 accgaatgtc tttctttccg tacatagttg ccatcttctt tatcttctgt atgggactca
     1141 tgattggcgg agatcgtcaa agtattatct gaatattcaa ctgtcgtgtc ttctttgtca
     1201 cagccaggca tatcagcagt tagtttgtat tctttttcat tttcgactaa atctactttt
     1261 ggataacttg aaacacctaa aaaatcattg aatgctggac taaacacgtc attgaaatca
     1321 gggaacatgt cgcgaatgct aggtacattt gccatttttg atcatccttt caataagtat
     1381 tttttattta tccctattta cgtaataact ctattttgaa aaaaatgcaa gtataatggt
     1441 tagctttgtg aatatttcat ctaatacgat acaaaggcta tctttctaat ttgaaaaagg
     1501 gatcattaaa ataataagaa gaaaatatgt caaaaggtaa aaaagtaaat tcttctatcc
     1561 aaatatagaa aaattgaatc tagaaaaccg cccgacaata aatttcatta actcagttga
     1621 ccgaaaatga agtagatacc aaaaatttat caagagagca agtagagaag tgagtatatt
     1681 cataagagaa atagctgtaa cgaattatta ggttaatgca aatgcttatt tatactccgt
     1741 ataactttct cagaaaaaat gataccaata atgacttgct agtactgtaa atccgtataa
     1801 tatcatctaa tcaaaatggt gttccatttg catctgtcat cgtaatcgat ccttcgggtg
     1861 acactcgata aaaaccaacg cttccagatc ctccttggga acggatttgt ttgctggaag
     1921 ctgtgaacaa ataatctcga tcaatttttt gataaaagct aataacaata tcgtcacttt
     1981 gtaattcgga acggtgggca ataagaaata gaagtgcttt gtcagagttt tctaatggaa
     2041 gagaaggtac agtgctttct tgcatttcag atgttgaaga aatgctaaac gactgaatac
     2101 ttgattggct atgttgcgaa tctacattac cagtagaagt attagtaatg gaagtagtag
     2161 aagtactttt agttgaacca acctcagttg ttgaaatggc tgctgaagat tctttaacag
     2221 aattctttgt tttatatcca caggcagaaa aaagtattac agttcccaac aagcctgcgt
     2281 aaatcccttt atgcatgata gctcctccta aaatagatta tctttattca gtatatcact
     2341 taaacaaaga aaagcagatg gtttaaaatg aaaaaacctt cccaataaag ggaaggttca
     2401 tgaagataat aactttttta ataattatag ctttctaata tctttcatca acttttctag
     2461 taatcattgg gaaaaatttc aagcagtaga tcgcacaaat acctacgacg atataaatga
     2521 tcttcgcaaa aatagttgtt gaaccaccag caatcatagc tactaaatca agttcgaaca
     2581 agcctaccaa cagccagttc aaccctccca caatcaataa agttaatgca atagcatcta
     2641 aagttttcat tagaattctc ctttcttaaa tgataaaaca attatatatc aaaaagagaa
     2701 acattgctta tataacgctc aggaatttta gcaatctatg caaaaagatg aaaatttttt
     2761 ttgctcttcc attagtacac attttttagc tgaagctgta aatttcatgt cttaattttt
     2821 tttagtgagc ttttatactg gatttgtaag aaaaaagaag gagaggatca catatgtcgg
     2881 attggttgga tattgcagga aaagtagtaa ttgtaactgg aggttcctca ggaattggaa
     2941 gaagtatcgt cgaaaatttg ttgaagcaga atgcacaagt agcgaatttt gatgtaactg
     3001 aatgccgtat acagcatgaa aacctactat ctttaaaagt cgatgtgtct tctaaaacgg
     3061 acatagaaga agggatatat aaagtaatga aacatttcaa gacgatcgat ggtctagtca
     3121 ataatgcagg aataaatatt ccttctcttc taatagatag aaatcatcca aaaagcaagt
     3181 atgaattatc agaacaagtt tttgataaga tgatcgctgt caatcaaaaa agtgtatatt
     3241 tgatgagcca agcagttgga agaatcttgg tgcaaaaggg atcaggagtg atcgtgaatc
     3301 tttcttctga atcaggattg gaaggatcag aaggacagag ctgttatgct gctacaaaag
     3361 cagcgatgaa cagttttact cgttcttggg caaaagagtt aggaaagagg aatgttcgtg
     3421 tggtaggtgt tgcaccaggg atactggaag aaaccggttt gagaacacaa gaatatgaag
     3481 aagctctttc ttatacgaga ggtataagcg tcgaacagct gagaaacggt tacagtcgaa
     3541 caagtacgat ccctctagga aggagtggta agctgcaaga agtggcggat ctagtctgct
     3601 attatctttc agaaagatca agttatatca ctggagtcac gactaatatt tcaggaggta
     3661 aaacaagagg ataaaggata ggggggacgc acgtgacgct agtaaacaga tggtaccaat
     3721 tattgaaatt actagtcact cacaagaaag tttcaatcca ggaagtgcaa aaagaaatca
     3781 aaaccagtaa tcaaaccata aaaaaagata ttggggagtt gaatgaagaa attgccggta
     3841 ttgcaaaaat catccaaaaa aacaaacatt ttgaacttga aatttatgat tttgattttt
     3901 ttgatgagat catgcaagga aaattgaaaa cagccagtga tttcaattcg gcatccaaaa
     3961 gaatcgctta tttactaaat aggctgatcg aaacagagga tttcttacgt atggatgatt
     4021 tgtctgaaga agtcggtgtc agcagaggaa cagtggtcaa ggatctaaag acattaaaag
     4081 agatgatcaa tgattttgat gtaaagatta caggcacacc aaataaagga ctaagaataa
     4141 taggagatga gctagaatta cgactacttt tattttattt tgtttctccc tacttttcag
     4201 agacgaaaac agaacagttt ctagaagaaa aacaagcaat caaacatttt cagaagaaga
     4261 cgaatgctag taaacaagaa atcacccttt taacgaaagt tatcggtatt tctttgaata
     4321 gaatctctag taactatctg ttgaagaagc ccatcaatcg ttacagtggg tgttttgaat
     4381 atatccaaga attcaatgaa ctgatcaatc agttggaaga aatctatgaa ctaactttga
     4441 gccaatatga aaaagatttt atcagttttc ctttgaacat catcaacaca agtataacga
     4501 tgataaggaa agctaactct gatttgcgct tatatttcga ccccatgatg atgcgtattc
     4561 gacgattaga tctcattgat ctggatgagt ccttcttata tcaagagatg aaacagcacc
     4621 tctctttatt gataaatcgg gtaatttttc gttatcgatt gactgattta ttttatggtg
     4681 agatagaaaa aaagtatcct ttttcttacc aaatcgctag cgaatgcata caagcattag
     4741 aagctatctt gcaacataag atctctaaag tagagatcag ctacctaacg ttgtatttgg
     4801 agttagcatt tcgatatcaa aaagagcatt tttcctctaa aaaagtagcc attgttcata
     4861 cgacaggaaa aggaacagca ttaatgatcc aaagacaaat caaaaggata ttggggaggg
     4921 atatacaaat aacacatgtt tcagaagaac aatatgaaaa agtagatcta aacaaatatt
     4981 tcgctgtttt tacaacgatt ccgttaaaaa atgtaaatga agagacaccg gtgatccatt
     5041 tgactaatct ttttgatgac tcttggttaa gggcacaatg gcaaaaagca aaaaaaaagc
     5101 gattagccgg gtttcattct actgtttttt tctatcaaat atggaaagaa aaaaagacgt
     5161 atcaagaata tttaaacaaa ttagtcgctc ctttgatcag aggctattat gtggatgaag
     5221 aatttgaaaa aaggatcttg aaaagagaat atcagcaaag cacatttgtt aacaaagaat
     5281 ttgcttttcc tcacacaacc aaccagctat ctcaacacat tgttttatca gtagggctaa
     5341 taactgatca aggtttagca gaaacaggag gaaatggagt tattttttta tttgccatac
     5401 ctgaagaaat gacggctgaa gttgagaatg aattatttga gctatacgat atcctatttg
     5461 aactcataaa aatgggaata gatgagttta ttgaattagc accgacacaa gaatcatttt
     5521 taaaactaat caaaagtaaa ggagagagac ttcatgaatg atatgtatct attcatagtt
     5581 ttcgcagctt cagcttatgt gctgcaagca gttatcagtt ggaagcaact aaagcatttc
     5641 aatcaaacat atagcgaact gcgaagaaaa ggaaaagtag cgattggtaa acgacctggg
     5701 aaaatccgtt caggcacgat tgttatgcta gctatagacg atcatgatca agttttagaa
     5761 gtcagaaaaa tgcaaggggt tacatctttg gcaaaatttc attcattacc tgtctatgcg
     5821 ggtgaagata tccattacat cgatcgttac catccctcag ttcgagcgga agatcgtttg
     5881 acacaagcag ctttagaaaa tgccagagaa gtatacttac gaatagaggc aggaaatgaa
     5941 aaaagtgaac aaccttcatt gccttttatt gctatgctca ataattttcg gatatggaaa
     6001 agtacgatca aagaaaaaag gagtgacaaa cgatggatat cataacaaaa tttgctgagg
     6061 gatttatgag gctgttccaa acaggtgcag aaacattcat aagctggatg acaggaatcg
     6121 taccagttgt cttgatgctg atggttgcaa tgaatacgct gattgctttt ttaggtgaag
     6181 accgagtaac gaaagtagcc aaattatcag cgaaaaatcc gcttactcgt taccttgtgt
     6241 taccgttctt atctgctttt atgttgggaa atcctatgtc atttacaatg gctcgtttcc
     6301 ttccagaata ctacaaacca agctattatg ctgctcaagc tcaattttgt catacgagca
     6361 atggtgtatt cccccatatt aatcctggag aattgtttgt atggatgggg attgctcaag
     6421 ggatcgaaac cttagggcta aattcgatgg agctggctat ccgatacttg cttgtgggac
     6481 tgctgatgaa ctttattggt ggttggataa ctgattttac tactggattt gtatgcagac
     6541 agcaaggaat cgttcttagc aaaaaagtag agctttcagt tgattagaga aaggagagtt
     6601 ttaaatgtat ggtgatatta agatcgtaag aggaaacggc gggtatggag gtcctttgat
     6661 tattaggccg acaaaagata aacacaagtt catctatgtc acaggtggag gtgagaggcc
     6721 aatgatcgta gataaaatag aagaactgac aggtatggag tctatcaatg ggttcaaaac
     6781 atcaatacct gatagtgaaa tcgcgcttgc aatcgttgac tgtggaggga ctcttagatg
     6841 tggaatttat cctaaaaaag ggataccaac catcaatatc gtttccacag gaaaaagtgg
     6901 cccattagca caatatatca ctgaagatat ttatgtttca gcagtagggt tagaacaaat
     6961 acagccacta atggaaactg atgataacaa agaaacagta aatactgcat ctccagataa
     7021 aaagtacaaa tatgatactt ctaaaaagat aaccgagcaa aaagcagagc agcaaaactg
     7081 gatagcaaaa attggaatgg gcgcgggaaa agtagttgct acattcaatc aatcagcaag
     7141 agaagcagta gatacgatga tccggacagt gatccctttt atggctttcg tttccctttt
     7201 gattggtgtg atacaaggtt ctgggatcgg taatgtattt gctaacatta tggcaccttt
     7261 agcaggaaat gcagttggat taacaatcat tggctttatt tgttcactgc catttttatc
     7321 tcctttgctt ggtccagggg cagttattag ccaagtgatt ggaacattga tcggtgtaga
     7381 gattgggaaa ggaaatattc ctccccaatt agcattaccg gcactatttg ctatcaatac
     7441 tcaaaatgca tgtgatttta ttccagtcgg tctaggtttg gaagaagcaa aagctgagac
     7501 agtagaagta ggtgtaccat cagttcttta ttcaagattt cttaacggca tcccacgagt
     7561 tatcattgct tgggtagcaa gttttggatt atatagctg
//
LOCUS       DADGKS010000111         7553 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.116, whole genome shotgun sequence.
ACCESSION   DADGKS010000111 DADGKS010000000
VERSION     DADGKS010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7553
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.116"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(42..1168)
                     /locus_tag="JXV47_002672"
     CDS             complement(join(42..940,940..1168))
                     /locus_tag="JXV47_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAX1488671.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAGSHILSENLNSLVQFIEKWCKDYTVS
                     LLCRLLEIPRSVYYFYKNKPLTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKE
                     GISVSLKHVQKLMKQLNLRSIVVKKYRPQRSNKPIISKENLLNQDFSTETICEKWAAD
                     ITYIPTKKNGWCYLSSIMDLHTKKIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMIL
                     HTDLGSQYTAREVEQWLKTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDF
                     EEANRALFSYIEGFYNRNRIHSSIHYLTPQEFEELAKEKMA"
     gene            complement(1572..2354)
                     /locus_tag="JXV47_002673"
     CDS             complement(1572..2354)
                     /locus_tag="JXV47_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488672.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENGKKDYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(2419..3255)
                     /locus_tag="JXV47_002674"
     CDS             complement(2419..3255)
                     /locus_tag="JXV47_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAX1488673.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(3273..4682)
                     /locus_tag="JXV47_002675"
     CDS             complement(3273..4682)
                     /locus_tag="JXV47_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAX1488674.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(4696..6519)
                     /locus_tag="JXV47_002676"
     CDS             complement(4696..6519)
                     /locus_tag="JXV47_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1488675.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
     gene            complement(7362..>7553)
                     /locus_tag="JXV47_002677"
     CDS             complement(7362..>7553)
                     /locus_tag="JXV47_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488676.1"
                     /translation="LQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYY
                     PKKDRIYVEIPYAEVLMLN"
BASE COUNT         2298 a         1560 c         1207 g         2488 t
ORIGIN      
        1 ggatttgagt caatatcttg gacacatttt agtagagacg gttaagccat tttttctttt
       61 gctaattctt caaattcctg tggggttaga tagtgaatcg agctatggat tcgatttcgg
      121 ttataaaatc cttcaatgta gctaaatagc gctcgatttg cttcttcaaa atctgagtag
      181 ctagtcgtgt agacttcttc ttttttcaat gaggcatgga aagattcgat tccagcatta
      241 tcataaggtg ttccttttct actataagaa tgccttattt tgttggtttt aagccattgt
      301 tccacttctc ttgctgtgta ttggctgccc aagtcagtgt gtagaatcat tccttctgga
      361 atgtgataat gtatttttgc tttattcaat gtttgaatga cacaatccac agtcattcgt
      421 tttgaaaatg tataactaat aatttttttc gtgtgtaaat ccatgattga agataagtaa
      481 caccaaccat ttttcttagt aggaatgtac gtaatgtcag ctgcccattt ctcacagatc
      541 gtttcagtag aaaagtcctg atttaagaga ttctcttttg aaatgatcgg tttattagac
      601 ctttgaggtc tatatttttt aactacaatc gaccttaaat ttaattgttt cattagcttt
      661 tggacatgtt taagagatac tgaaatccct tcttttaata aaacttgatg gatctttgtg
      721 gcaccatagc gttgtttatt cgtaaaaaaa attgttgaaa tcttcttttt caacttatta
      781 tttctgattt ctgtagctgt caacggttta ttcttataaa aataatagac acttctaggg
      841 atttctaata accgacataa caaagaaaca gtgtaatcct tacaccattt ttcaataaat
      901 tgaacaagcg aatttaggtt ttccgagaga atatggctgc ggcttttttt aagatttcaa
      961 gttcctcatt taaacgagca ttttcttttc tcagttcagc tacttctttt ccagtcagtc
     1021 ctgtggactg atcaggtaaa tataaattct tccatttgta aatcgttgct tcagataagc
     1081 catattcttt cgctaaccct cgaacagaac gtccagtttg attcagttca acaatcattt
     1141 gtttaaaatt ttcttcatat cgggtcataa aaattcatcc tctcgtagat aagtttaatt
     1201 tattcttgtc tctacgaaaa gctgtctaag atttgatact aacaccaagt tatctttaga
     1261 accatttcag atacatatga aacaattaca tatgattttt tcataaaaaa acagtactgt
     1321 ctagtagtat aaaatataca aatttcttaa aaattttttc actaaaatca ctacctgaaa
     1381 cagtctaaaa cacttatata tcaacgttta atgaaactat ctccgtttca tttcagatac
     1441 aaataaatat agtcgggctc caaatccgaa aaaaaatacc cccagtagct tatcctaagc
     1501 tactggagat gtataagtac ggtcatataa caacggggta gggtaaataa atgaaaaaga
     1561 tggaagaatc attattcaat aactttttta aatacttcgt tgtaatcagt tacctgtccg
     1621 ttcttaaata ccacagaata atcttttttc ccattttcaa gtaaccgaag tggaatgtct
     1681 ttaccaactt gctctgtcac tgcattactg atacctgtta gattagctaa taaatctgat
     1741 aaagattgag catctgtaga aatctctgta tcagtattta tcgtgattcc tttatcttca
     1801 tttacaagct tccaagtagg tggtatagct gtgtatgttt cgatgaatga atcaattctt
     1861 tcatctatcg tcttcccagt atctacttct gtctcattac tcttagatga atcgattctt
     1921 tcatccatcg tctgctccgt aactgcttct gtctcattat tctcaccgga aactctcttc
     1981 acacccaaac ttatatattg tccatcttta gtgtgcatag ttaaaattcc cacgctttta
     2041 ctaataaatt cactataacc agttctttca atagagactt caatgtattt cacactatca
     2101 tactcaaaag aaaaatagac atgtaaaagc attttgttgt ttacatctac ataataatcc
     2161 tttgactcta cttgagacct tcctatacgg aatacagctt tactgtctga tatctctata
     2221 ccagcatcct tattattaat ctgccaatct ccaagtagct cttctggcaa gctagtagtt
     2281 tcttgtgaac actttaccac ttcactggta gaggtcgaaa cattcacctc cgcactgtta
     2341 gaagaatttt ccaaggaatc aggagcctta gcacaaccaa caagtcttta tatattgtgc
     2401 agccgatatt ttcttcattc agtacaccct tgaaatatgc agtgttagat aaagcagttc
     2461 gtcctgattt gctgaggcac ccatctcttc ttgaacgtac tccttgattt tcaaggccgc
     2521 ccgatactct ttcggaaaac gctgcttcac tgaagccagc aaaaaatcat ccttctccgg
     2581 caactcttcc ttcttaatca ttcgggcaat aaaaaactgt aaatgcgtca caaatcttaa
     2641 gtaaagcatc gaatctttat caaccttttt ttcgggaaac agatatccta gcatagccaa
     2701 gatatccttt agtgctctta ccgagagcat ggtttcttcc atatttgctt gttcactttg
     2761 ggcatttaca atgtgaaacg caatgtttcc agcctcctct tctggcaact gaacattcat
     2821 ttttttgttg atcaattgga tagcatagca gccgatctca aattcttttg ggtaatactt
     2881 ttgaatttca atcagcaggc gattttgaaa aacaatgcct ttttgactgc gttcaatggc
     2941 atgcttcaag tgatcaacca aggtaaaaaa tagactttta ttcagcttaa agtcaaactt
     3001 ggcgttggca taatcgataa ttcgcttgac gcaaataatt agatcatccg gagcagcctc
     3061 aaacagttta atgtaatcct tttttagagc atcagaaagt gaatctaatt taaatacttt
     3121 ttggattttg tcagccggaa ccaaatcgcc tttctttagt tgaaatccaa tccctttccc
     3181 catcaaaatt acttctttgc cttgcttatc taagcaaaga attaaactgt tgtttaacgt
     3241 tttaattact ctcattagat tcaccgttct ctctaagcta agccatttct tgcgattact
     3301 ttttgatacc aaaagaagct ttcttttttt attcgtttta attctttaag attctcatcg
     3361 gttcggtcaa catatataaa accataacgc ttattgaagc cttgatgggt actaacaaca
     3421 tcaatcgctg accaaggtaa ataaccaaaa acatctacac catctgttaa agctgcttga
     3481 atagccagaa tatgtttggc tagataatca attcgatcct ggtcattaat tcgtctatct
     3541 tcctcaacta tgtcgggtgc cccatagcca ttttcagtaa ttaaaatagg taaatcatag
     3601 cgatcgtaca atttcctcaa tgttaatcgt agtccagtag ggtcaactac ccagccatat
     3661 ggcgttttat ctacataagg attttcagct gcccggtaga caccttcttc tcccaacatg
     3721 atctgttgat cccccgctct agcggaaaca tctgatccgt catttttgct ggcagcgatg
     3781 gtggcagttg aataataatt aatcgcaata aaatcgggtt taccggagga taaaattgcc
     3841 tgatcctctg cctcaatttt aggatataat ccacgatcat tcaaatagtt ttcaaacaaa
     3901 taattgtatt ttccccgaac tgctacatct aagaaagacc agcctctcaa tgtttcccaa
     3961 ttatgggctg caattgcatc ttctggactg gaggtagctt gatacatagc cgttaaattg
     4021 attgctggac cgatttttcc tttaagattc aactgatgat acaagtgaat tactctagct
     4081 tgagctaata aaacatggtg attaatttga aagagttctt tttttgaagg cagctctcca
     4141 cttggtggca aaccaatcgc tccaggatga aggatcatcg tgttttgctc attaattgtc
     4201 agccaatagt tcaccttgtc accatactca gtaagcaata cctgtacata gtccacaaaa
     4261 taatcgatag ttgctcgatt taaccaaccg ccctgctcct ctagaaaata aggtaaatcg
     4321 aaatggtaca tggtgacaat cggttcgatt ccctgattca ggcattcatc aattacttga
     4381 tgataaaaag aaattccctt ttgattggtt ttattatttt caatatccat aattcgcgtc
     4441 caagcgatgg aaaagcgaaa agcttttaag cctaattctt taaacagctg tatatcttct
     4501 ttatagtgat ggtaaaaatc cgaggcaact tcaaaattag ctaccccttc tgtatgctga
     4561 tacttgtcaa taatagacgg ttgtttccca tcctcctgat aggcaccctc tgcctggtag
     4621 gcactaatgg aggcacccca taaaaacttc tctggaaatg ctgaaagctg tttgtattgc
     4681 acaaaaatcc tctccttaac taatttgcat caatggttcg tgttccttta agcttccgct
     4741 tgcttcacta attcctgcgt aattttcact gttggtcact accacaatca ctgtatcatc
     4801 gtagccagcg tttctaatgg cagcgaaatc ggcgttgatt aataattgtc ctgctgacac
     4861 ctgatctcct gcttttacaa atacttcaaa gggttcccct tttaaattca cggtgtcgat
     4921 ccccacatgg atcaataatt caataccttc tttagaacgt agaccaatcg catgtttaga
     4981 ttctaaaata gtaatgactt ctccctcaac aggtgaataa atgctgtttt cttctggatg
     5041 aatggctacg ccctttccca atagtccctt agaaaagaca gcatcgttca cttcagaaat
     5101 aggacacacg gttcctttta ccggattttc aacaatgact gcttcggcta ttgccgtttg
     5161 ctctgattca tcagaagtat cgtcaaatcc aattagataa gcaatgataa aggttgcaac
     5221 aaaggcgatt acacacgtaa taattgcgtg aacaatattc attggatttt ctccaataaa
     5281 ggctggtaag gctgctaagc caggggaaac aaaggcatat ctgactaaac cgctcaagcc
     5341 agcatacaaa ccagcaattg caccaccaat catggaagca actaatggtt ttttcagctt
     5401 caaggttact ccatagagtg aaggctcagt aattcccatt aaagcagtga tcccagtgga
     5461 cacagctagc tgcttcaact ctttgttttt agttttcgcg gctacagcaa aggtagcacc
     5521 tgattgagca atattagaag ccagcattcc tggcccattg atcatttcag aacccgtact
     5581 gctcaattgc atagtagcga ttggcgtcat tgcccaagct gtacccgtaa ccaccaaaaa
     5641 tggctgcaaa ccacccatca aaaatggaat taaccaagct gctttgccgt taatccattc
     5701 agcccccatt gctataagat cgttcagcaa cgttccaaac ggtccaatga caaccaacgc
     5761 taaaggcccc ataattaaaa ataccagcat cggcttagta aagaatttaa taaacgaagg
     5821 cgaaattcga tccgcaaagg gctctacata ggacatgatc caaacagtaa agataatcgg
     5881 taaaactgat cccgcataat ctgcagctaa taccggaatt cctagaaaag aaacggcatc
     5941 gccagtagaa aaaagctgtg aaatatttgg atgaagcaaa atgccagcaa cagtaatcgc
     6001 caaaattggg ttgacatcaa actttatggc tgccccatag gctaatagta ctggcataaa
     6061 ataaaaggct gcatcagcaa tagtattcaa aatgatgtaa gtttgactac tgtctgatag
     6121 tacaccagtc aaagtcaaga cggccaaaat ggcttttacc atcccggcac ctgttatagc
     6181 tggaatcatc ggtgtaaagg tggtagaaat gacactaatc aatcttgaaa taatactttc
     6241 ttgattgtct gaagaggggc cctttttaat tgaagttccc acttcctttt gaatttcctt
     6301 gaaggctgtt tggacttcat tgccaatcac cacttggtat tgtccaccgc tatccaccac
     6361 actaattaca ccaagtgttt tttctaaggc tttcgtatcg gctttccttt tatctttgag
     6421 ttcaaaacgc agtctggtgg cacaatgggt taagctgacc acattttctt ttcccccaac
     6481 ctgttgcaat acatttcttc ctacttctct gtaatccatt attctctctc cttaaagcag
     6541 taaaaaagac caagtcaaac cacgccccaa tcaacattga agtgttagtt tgtcttggtc
     6601 ttgcctgcat aatcagtaac atgccaataa cgttattttg ctgtaatcca ataatagcac
     6661 attatgatag cgcaatcaac agggaattta attttttatc ttttcgtttg accgtatagg
     6721 gtaatataac agttagatca catcaactag ggtatatctg cgtatactta ctgctaaaat
     6781 aagtatatct aatattaact ataccagtaa aaccattcct acataaccag cgggaaattc
     6841 ccaaaatcgt gaaagcatca aaaatgcata taacggatca cacaacttca acaattctgc
     6901 tcttgggaaa aattgatgaa tttggtgagt aaaggatgga ataaacagca ttccaacaat
     6961 ataggcaaca atagtgatac ttgttttttt ggtaaaaatc agtaagcaat agccaatttc
     7021 aatcattccg agatataaag gtatcgatag aatgatttgg gctagtattc ttaaaaatta
     7081 actagcaaat gtttaaactg atttatttct aatctacatg tagtaagtat ttcaattcca
     7141 ccaattatca ataaaaatac caaacatatc cataataatt ttttcttttt catttctttt
     7201 atattgttat aacagtgaat aacataaaaa ttcccgacaa tcattgtaat atttttttgt
     7261 cacctgtatt agtatttaat ttataggaaa ctataaaaac tccctagtga atttacacct
     7321 ttgggagttc ctgtttggac ggtatgcata atacatttaa atcaatttaa cattaacacc
     7381 tcagcatatg gtatctccac atatatacgg tctttctttg gatagtactc aatatttatg
     7441 ttgatagcac ttccattgtc taatatagct ttagcccggt atgtgttatc tccattttca
     7501 tgagtaatcg tcacatcatc acatgatcga tttaagttgt actgttcttg taa
//
LOCUS       DADGKS010000112         7338 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.117, whole genome shotgun sequence.
ACCESSION   DADGKS010000112 DADGKS010000000
VERSION     DADGKS010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7338
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.117"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..329
                     /locus_tag="JXV47_002678"
     CDS             <1..329
                     /locus_tag="JXV47_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HAX1488677.1"
                     /translation="KDVFLEIEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGT
                     DADEVIEERMKVAKEEIEMMALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYI
                     KMLKEM"
     gene            334..639
                     /locus_tag="JXV47_002679"
     CDS             334..639
                     /locus_tag="JXV47_002679"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAX1488678.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            892..3300
                     /gene="priA"
                     /locus_tag="JXV47_002680"
     CDS             892..3300
                     /gene="priA"
                     /locus_tag="JXV47_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HAX1488679.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            3315..3806
                     /gene="def"
                     /locus_tag="JXV47_002681"
     CDS             3315..3806
                     /gene="def"
                     /locus_tag="JXV47_002681"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAX1488680.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            3799..4737
                     /locus_tag="JXV47_002682"
     CDS             3799..4737
                     /locus_tag="JXV47_002682"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HAX1488681.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            4737..6095
                     /gene="rsmB"
                     /locus_tag="JXV47_002683"
     CDS             4737..6095
                     /gene="rsmB"
                     /locus_tag="JXV47_002683"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HAX1488682.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            6108..6848
                     /locus_tag="JXV47_002684"
     CDS             6108..6848
                     /locus_tag="JXV47_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HAX1488683.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            6845..>7338
                     /locus_tag="JXV47_002685"
     CDS             6845..>7338
                     /locus_tag="JXV47_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein kinase"
                     /protein_id="HAX1488684.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETS"
BASE COUNT         2439 a         1366 c         1649 g         1884 t
ORIGIN      
        1 gaaaagatgt tttcttggag attgaagtcc aaggagcaaa acaagtcaaa gaaaaagtgc
       61 ccgatggtgt attcatcttt ttgactccgc cagatttagc ggaattaaaa tcacggatcg
      121 taggccgagg aacagatgca gatgaagtaa tcgaagaacg aatgaaagtt gcaaaagaag
      181 aaatcgaaat gatggctctt tacgactatg ctgttgtaaa tgatgaagtg ccgctagcag
      241 ttgaacgaat caaaaacatt attgccagtg aacattttcg agtagatcgc gtaatcggta
      301 aatatattaa aatgttaaag gagatgtagt cttatgatgt taaaaccttc aattgactca
      361 ctattagatc gtgtaaattc aaaatattct ctagtgattt tagcaagtaa acgcgcgcat
      421 gaattggatg caagtgcaca gcctactcta gattcttttg attcagtaaa aagcgtcggt
      481 caagctttag aagaaatcga tgcaggaaat gtagtcaatg atccacatcc tgaattaaaa
      541 cgtgaacgtt tgaagatgga agaagaggaa cgtcaagcac aaaaagagcg tgaacaacac
      601 gaattggaat cacgtatccg tgaagagcaa aaaatgtaat aaagaaaaat agagcgaaca
      661 tctaaaaaga aaagcaaacc cagctgtttc cttttcaaac attcgccact tattgtctgg
      721 tagaaaaggc tgtgtctgaa ctttttgaca cagttctttt ttttcttatc tgctgttaat
      781 tttttgttag gatttggcag aagataagac aaatccatcg atctctagta aaataggcaa
      841 ggaacttttt gtcgcttgat aagaaaagac aaaaaaagga ggaaacgaac catgacatta
      901 acagctgaag tcattgtgga cgtacctact atgcagaccg atcagccatt cacttatttg
      961 gttccctctg aaatggaaac agctttgcaa gtcgggatgc gagtagaagt cccttttggt
     1021 aatggcaatc gtcatgtcca aggatttgtt atggctatcc aaaaatcaga agaatcagct
     1081 aatccatctt tgaaggcagt tattcgtttg ctagaccttg ctccggtggt caatgaagaa
     1141 ttactttcat tagctgatta tatgaaaaaa attacttacg cattcaaaat cacttgtcta
     1201 caaacgatgc ttccgagtgt gatgaaagca gaatatgata aattgatcta tcctttggca
     1261 gacacaccag aagttcaggt attgtttgat cagcgagaag tgatttcctg gaaggaagca
     1321 gaagaagaag gcagcctttc tcaattgatt cgctggcgcc aagagcaatt agtagatatc
     1381 aaatatgaag tccatacacg aaataaagta aaaacgattc gtttggtccg ttctttgtta
     1441 actgaaaagc aaatcgaaga agaatgggca aaattacggc aaaatgccaa gaaacaaaaa
     1501 gaacttcttt tgtgtttatc tgaactgagc caagaagaac caattgctta tttcaaaaat
     1561 aaaggaatca gtactgctgt cttgaatcaa ggaaaagaaa agggctggct ggagtttata
     1621 gaatcagaac gttatcgcga cccttataaa gaccgagtat ttgaccaaac gacggcattg
     1681 gaactgaatg cagaacaaaa aaatgctgtc gaacaaatca tcacagcagg tcagcagcaa
     1741 aaagatcagg tctttttgct ggagggaatc actggcagcg ggaaaacaga agtatatctt
     1801 caggcaatcg ctgatgtttt gtcagaaaat aaaacggcta ttatgttagt gcctgaaatc
     1861 gcattgactc cgcaaatggt cgagcgattc aaaggacgct tcggagaatc agttgcggtc
     1921 ttacatagcg gactttccca aggtgaaaaa tatgatgaat ggcgcaagat tgagcgggaa
     1981 gaagcgcaag tagtagtagg cgcacgatct gctatttttg ccccgctgaa aaatatcggg
     2041 ctgatcatta tcgatgaaga acatgaatca agttacaaac aagatgagac accgcgttat
     2101 catgcgagag atctagcaat ttggcgcagt aaatatcatc attgcccaat agttctagga
     2161 agcgcgacgc cctctttaga atcaagagca cgagctcaaa aaggcgttta tcagttattg
     2221 cagttaaacc accgagccaa agcagctgca cagcttccag ctattgagat cgtagatatg
     2281 cgtgaagagt ttcagaatca tcggacctct actttttctg ctaatttgca ggaaaaaata
     2341 caaaatcgat tagacaaaaa agaacaaact gtcctactgc tcaatcgtcg aggatattcg
     2401 tcttttgtga tgtgtaggga ctgtggattt gttcttccat gtcctaattg cgatatctct
     2461 cttacactgc atatggatac acgttcaatg cgctgccatt attgcggaca tgaagaacct
     2521 attcccaatc gctgtcctaa ttgtggcggc aataaaatcc gctactatgg aacaggtact
     2581 caaaaagtag aagaggaact ccgagaactt tatccgcaag ctaggatttt gcgtatggat
     2641 gtagatacca ctcgaagaaa aggggcacac gaacagattt tacaaaaatt cggtgcaaaa
     2701 gaagcagata tattattagg gacacaaatg attgctaaag gtttggactt tccagaagtg
     2761 acattagttg gggtgttgaa tgctgatacc tccctgaatt taccggattt tcgttctagt
     2821 gagcatacat tccaattgct tacccaagtt tcaggacgag cagggcgagc ggaaaaagca
     2881 ggcgaagtcg tgatccaaac attcaatcct caacattacg ccatagaatt ggctaaaaaa
     2941 caaaattatg agcagtttta tcagcaggaa atgcatgtac ggcatcgtgg aggctatcct
     3001 ccttattact ttactgtgaa aataaccgcc agccatcctg aagaacaagt agcggcaaag
     3061 aaaatctttc agattgccaa tcagctaaaa gaagtgttaa gccctcaaag cttgctatta
     3121 gggccaacgc ccagcatgat tttgagagtg aaaaaccgat attattatca actaatcatc
     3181 aaatataaac atgaaccgaa tcttcctcat gttttggatg aaattttgaa tggaagccag
     3241 aaagaacagc gacaaggtct ttttgtggca attgacaacg aaccattaaa ctttatttaa
     3301 gaaagggcca aattatgcgc tatcctatat tgatccaccc taatgataaa ttaaaaagaa
     3361 ctgctcagcc aatcgatgta atcacggacg agacaatcgc tttattagac aatttatatg
     3421 agacaatgat tgcgaatgac ggaataggga tcgctgctcc tcaagtagga caaaacaaga
     3481 gaattgctgt gatcgaagta gatgaaggcg agaaatttga actgattaac ccagaaatca
     3541 tcgaagcaaa aggtgaaagc cttgacgtag aaggttgtct cagtattccg catgtctatg
     3601 gaacggtcaa gcgagcagat gaagtgaccg tgcgttatta tgatcgagac ggagaagaga
     3661 tagaagtgac ggcttttggc tatttagccc gtgccttcca gcatgaaatc gatcacttag
     3721 acggtatctt gttcattgag aaaatgatac agcagatccc ggaagaagaa cttgaagaat
     3781 atatggagga acatcttgat gactaagcta gtatttatgg gcacacctgc tttttctgtg
     3841 ccgattcttg aagggctgat agaatcaggt tacgagatcc aggcagtggt aacacagccc
     3901 gaccgtccag ttgggcggaa acgagtaatt acgccgacac cggtaaaaga agcggctctg
     3961 aagcacggta tccgtgtgct gcagccagag aaaatctccg gttcgccaga aatggaagaa
     4021 atcattgaat tggtgcctga tgtgatcgtc actgcggcat ttggccaatt cttgcctgaa
     4081 aagttattgc aagtaccaaa attaggggca atcaatgtcc atgcttcttt acttcctaaa
     4141 tatcggggag gtgcgcctgt tcattatgcc atcatgaatg gggagaaaga aactggtgta
     4201 acgatcatgg aaatgatcaa aaaaatggat gcaggcggaa tctatgcgca agaaagcata
     4261 ccaatcacta aacaagatga tgtagggacg atgtttgaaa agcttagcct tttaggaaga
     4321 aagctattgc tagaaacatt gcccaatatt ttggatggac aaaaaccagt acctcaagac
     4381 gagtcagaag caactttttc gccaaacatc acacgggaac aagaagcaat cgattggcat
     4441 aaaactgcag aagaaattga caaccaagta cgcggaatgc gtccttggcc aattgcattc
     4501 acgacctatg agggcatacg ctggaaatta ttatcggttg aagtattggc agaaactaca
     4561 gacaaagcac ctggtacgat catccggaaa gacaaaaaaa atctatggat tgcttgcggt
     4621 aaacagaccg tcttagccat caatgaatta cagccagctg gtaaaggaaa acaggccgta
     4681 catgatttcc ttaacggaag cggtcagcaa gttcagattg gtcagcaggt gaaataatga
     4741 aaaaaatccc taaaaaaatg aaaaaatcag tacgatatat ggcattactg acattagagc
     4801 gagtgaacaa gggtggcgcc tactcgaatc ttttgttgaa tgagatgatc aaacaaagcg
     4861 agctaaatca aaaagatgtg ggtttattta cagaattgat ctatggtacg attagccatc
     4921 agcgactatt ggaattttac gttgcaccat tgatcgctaa agcaaaaaaa gtggatgact
     4981 gggtcaagac gcttctttat ctttctgtat accaattaga atttttagat aaagtccctg
     5041 cacatgctat tttaaacgag gcggtcgaaa tcgcaaaagt aaaaggaaat cctgggacag
     5101 ggaaatttgt aaatggtgtc ttgaggaatt atcagcgtca aggagcacca gatctgcaag
     5161 gcattgctga tcctatcgaa agactttctg tcaaaatcag cctgcctcta tggatgacga
     5221 aacgactggt ggatcaaatc ggatacgaag aaactgaaaa gctcggttta tcgctatatc
     5281 agcctagcca tgctagtgcc cgagtagata cacgccgact ttccagagat caggccatca
     5341 ctgttttgca agaagaagag atcacagctg aaaaaagcca agtcagtcca tacggtatag
     5401 tagcgaaaaa agggcattta gcttctagct cattgttcca cgatggcgtc atgacgatcc
     5461 aagatgaaag ttcgatgctt gtagcgccgt ctatgcaaat cgagcctgaa catcatgtct
     5521 tagatgcctg tgcagcaccc ggaggtaaga cgacgcatat tgcttctttt ttagatccgt
     5581 catgcggtgg agaagtggtc gctttagatg tacacgaaca caaagtcaaa ctcattgaag
     5641 ataatgcagc acgtctaggt gtctcttctg ctgtctacgc tcaaaagatg gatgctagag
     5701 aagtcagtaa acagttcgaa gcagagcagt ttgatcggat tttagtagac gcgccttgtt
     5761 caggtcttgg gctgcttcgg cgaaaaccag atattcgtta taaaaaacag ccggatgaat
     5821 tagcgaattt accaaaaatc caattggaaa ttttagaaag ctgcgcacca actttaaagt
     5881 cttccggtat tctgacttat agcacttgta cgatcttaaa agaagaaaac caagacgttg
     5941 tttctgcttt cttggaaaga caccctgatt ttgagaggat tgatgttttg accaatccta
     6001 tgctacaatc atcaatcgaa gagaaaatgt tgactttgta tccgcatcag ttttacacag
     6061 atggattttt catttgttgt ttgcgcaaaa agtaatgagg tgaaaaaatg cagattgaat
     6121 atcaatcaga tgtaggaaga cgacgtaaca caaatcaaga ctatgccagt gtatttacca
     6181 gccgttcagg tctcaagctt gctgtattag cagacgggat gggtggtcat cgtgccggag
     6241 acattgccag tcagatggcg gtaacgaatc taggcgaagc ttgggaaaaa caagaagctg
     6301 ttgacgatga aaaaatcgcc caatggttca ttcaatcgat tcaagaagaa aatatgctga
     6361 tttatcagcg tggacaagaa cagccggaat ataacggtat gggaacaaca atcgtagcgg
     6421 ccgctctgtc agatgactgg ttcacgattg ccaatgttgg ggatagcaga gcttatttga
     6481 ttcgtgaaga taaaatcatg caattgacgg aggatcattc tttagtcaat gaactagtca
     6541 aatcaggaga aatcagcgaa gaaatggcag tgaaccatcc aaggaaaaat attttaacac
     6601 gttctgtcgg catgcctgga acagtcgaag tagatgtttc tactcatctt tggcaactaa
     6661 aagatcgact gctgttatgt tcagatggct tgacgaacat gctgtctgaa gaagaaatag
     6721 gaacgatcat caatcaagaa ggcccattgt ctcataaagt aactgagctg attgatcgtg
     6781 ccaatgaagc aggcggagcg gataatatca ccgttcttct tatcgaatat aaggaggaca
     6841 gtgtatgatc gagttgggca aaaaattaaa tggccgttat caaatcactg gaaatatcgg
     6901 tagcggtggt atggcaaatg tatttttggc gcacgattta atcttggatc gtgatgtagc
     6961 agttaaagtc ttacgatttg actttcaaaa tgaccagact gcgattcgac gatttcagag
     7021 agaagcttta gcagcaacag aactcgttca tccaaacatt gttagtgttt acgatgttgg
     7081 tgaagaagac aacatgcagt atctggtgat ggaatacgtc aaaggaatgg acttgaaacg
     7141 atatatccaa acacattatc ctgttcctta tgaaacagca gtaaatatta tgcagcagat
     7201 cctttctgct atttctttag ctcataacca tcaaatcatc caccgagatt tgaaacccca
     7261 aaacgtactg atcgataatg aaggtgttgt aaaaatcacg gatttcggga ttgctatcgc
     7321 tttatctgaa acatcgat
//
LOCUS       DADGKS010000113         7328 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.118, whole genome shotgun sequence.
ACCESSION   DADGKS010000113 DADGKS010000000
VERSION     DADGKS010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7328
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.118"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..272)
                     /locus_tag="JXV47_002686"
     CDS             complement(<1..272)
                     /locus_tag="JXV47_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488685.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKT"
     gene            complement(310..447)
                     /locus_tag="JXV47_002687"
     CDS             complement(310..447)
                     /locus_tag="JXV47_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HAX1488686.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEEKADKIISKEESA
                     S"
     gene            complement(449..895)
                     /locus_tag="JXV47_002688"
     CDS             complement(449..895)
                     /locus_tag="JXV47_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488687.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            complement(1058..3139)
                     /locus_tag="JXV47_002689"
     CDS             complement(1058..3139)
                     /locus_tag="JXV47_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488688.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDSVATSITSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFLAEIKGRMDSLNKQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLHVMYSNSIDFGGYDYSGNPNLMSKLKSSDFN
                     VGYHGSLTNVNGMLHFMSDGTGDIDMFTRINTPQLASGKTYTLSAKVRFDEGTTGAID
                     KLRLVYRTSPGEKILLEANSTNITTDDVGKEITIKGTANVNYQITNLDRFYISVSFSN
                     RDKINGGFKLYDIKIEEGSTATPYQPNLLDDPYWVGKTSLGKNIANKGTTFPIKSSAY
                     EIYKGNTEEELIIGQTYTITLKGTKPASQTFVAYNYWNVNFGDLKPVEGLTDVWSLTF
                     TPTKLEPGLPKDLRIFQSPKETAGACRIDWLKIEKGDTRTPNIEQYKYRGIGMRDSNN
                     PKDYVWDLEPSYVENNLATDIKVAEITGKANNYTDGKVSEINSQLTASINEVDTTAKD
                     AQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKLYREGKTVSIYFVALN
                     GKRSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYG
                     SDYTFAITYTI"
     gene            complement(3163..5454)
                     /locus_tag="JXV47_002690"
     CDS             complement(3163..5454)
                     /locus_tag="JXV47_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488689.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLINDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYDTAWTLDGGFNASFITAGEIVGITIRGTTLISDGTDYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNKPFLSFGAPNFR
                     YSNASYITDGDGSSLSINGSAGSSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKNFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDVRLKEDTAYDSTVLDQKRF"
     gene            complement(5464..6201)
                     /locus_tag="JXV47_002691"
     CDS             complement(5464..6201)
                     /locus_tag="JXV47_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAX1488690.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVAGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            complement(6252..>7328)
                     /locus_tag="JXV47_002692"
     CDS             complement(6252..>7328)
                     /locus_tag="JXV47_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAX1488691.1"
                     /translation="GAAWQAVWTPISDFLKNTWDTMTQWISIAWNGIVTTFHTIFDPV
                     VAWWNGIWTSISTTASNIWNSISATASSIWNSIKNTITSLVQAAATVIQNIWSTVSSW
                     LGGIWNSISSTASNIWNSVTSSISNAINAAKSAIQSVWNSISSWISGIWNGIKNTALN
                     LWNGITSTISSKVNDGKNAISSGWSNLTGIVSDIFNNVKSTIANIWEGIKKTVSAPID
                     WIRDKISGIFDNLNISIPHIPLPHFKLSGEFNPLKGKIPTLGVDWYAKGSVFNSPNII
                     GVGEAGPEAVLPLKRSVLQEIGDRILSSTSVSSRAQTIQPVNNYEFNFTIDGNADEVT
                     MKQTTQQIIDSITKIQNDNASAWR"
BASE COUNT         2104 a         1528 c         1152 g         2544 t
ORIGIN      
        1 aaagttttaa tttgttgcgt gtgttctacc aatttttctg catgtgtatc taatctttca
       61 tcgtgtttct ttagttcttc atgaatcatc aatcgatctg atttgctcga ttctaaatct
      121 ttagtcagca aatctaaatt gtgacttact tttgaaagag tctcagtaat cttcgagaaa
      181 gatgcagtaa ttggttttat tactaataaa atcaaagaaa cgatagcggt tattgatcct
      241 gctatcgctc cccattcccc taaattaatc atgtgacaac tccttgaatc aaaataaaaa
      301 gcacatcaat taagatgcgc tctcttcttt gctaatgatt ttatctgctt tttcttcagt
      361 aatgcacaac ggaacgaaaa ccattacttg ttcgttagtg aaacagcccc aatcatacat
      421 cattttcaca tcgctaaaac taaacatact actcacctcc ctttgaagct ggatttagtt
      481 gctctttaat ttctgaaatg tctttgctat tttgtaacga agcaagcatc atttttgaat
      541 tgatttgtgc taaactatcc gctttttctt tcaatgcagt attttcctgt ttaattgcta
      601 catcgcttag catgagtttg gcattgatct gttttaaatc gccgttctca ttttctaacg
      661 actcatacat tgctttgaga ttgtttaaat cgttgtgatc tagtgcgttc gctaaaataa
      721 tccattgatt caatttagga tcaaacattt gatcagcgat tgttaacggt tcgccatcag
      781 cacgaattcc ttcaagcggt ggctgatctg tgtaaggaac ggatacaagc atgtcgtcca
      841 atacttttcc tgcgtactct ccgccagtac gtccatattt ccaaatgttt ttcatttatt
      901 tccctcccag taattgaatt tcggtttcca atttggaatc ggtggttcga cttctgtgca
      961 ttcttccggt aaatgttctt catcattcac aatgatttgc tcgaatccgt aaggttcaat
     1021 tggtctatat gctgccttca tatcgattca cgcttttcta aatcgtgtaa gtaattgcaa
     1081 aggtataatc cgatccataa cttgagtttc ttcgccattt aatggctcca tctgcaccaa
     1141 tagataactg agcactgttc aaagtagaac ggtctatcga gccaaccagt tgctcaaaac
     1201 taattggtgg ccgatagcct tctggaattg ttagtatcgt tgaatcattt ccaccactgc
     1261 gttttccgtt taaagccaca aaatatatag aaactgtttt tccttcacga taaagctttg
     1321 ctgatccggt attcccgttt gtaactgtta atgtggtagt agctgtatca ttaatgcgtt
     1381 catcgatctt attgtctaat tcatctatag cagtcgcatt agcattcgct tttgtttgag
     1441 catccttagc tgtggtgtct acttcattaa ttgaagcagt caactgcgaa ttaatctccg
     1501 atactttccc atcggtataa ttgtttgctt tacctgtgat ttcagcaacc ttgatatctg
     1561 tagctaggtt attctcaaca tagctaggtt ctagatccca tacataatct tttggattgt
     1621 ttgagtctcg catgccgatt cctcggtatt tatattgctc aatattcggg gttcgtgtgt
     1681 cgcctttttc gatcttgagc cagtcaattc ggcatgcgcc ggccgtttct ttaggcgact
     1741 gaaaaatgcg aaggtcttta ggcaaacccg gttcaagttt cgttggtgtg aatgttagag
     1801 accatacgtc tgtcaatccc tcaactggtt ttagatctcc aaaattaacg ttccaataat
     1861 tatatgctac aaaggtttga cttgcgggtt ttgttccttt aagcgtgata gtatacgttt
     1921 gacctattat aagctcttct tccgtgttac ctttatatat ttcgtacgcg ctagatttaa
     1981 ttgggaacgt cgtaccttta tttgcaatat tcttacccaa cgatgtttta cctacccagt
     2041 aagggtcatc tagtaagttt ggctgatacg gagtggctgt tgagccttct tcgattttga
     2101 tgtcgtacaa tttaaatcca ccatttattt tatccctgtt agaaaaacta acactaatat
     2161 aaaatcgatc taaatttgtg atttgataat taacgttagc tgtacctttg attgttattt
     2221 ctttccctac atcatctgtt gtaatatttg tactatttgc ttccaataat atcttttctc
     2281 ctggtgatgt acgatacacc aaacgtaatt tatcaatagc tcctgtagtt ccttcatcaa
     2341 atcgaacttt cgcactcaga gtataggttt tcccactagc aagctgaggt gtattaatac
     2401 gcgtaaacat atcaatgtcc cctgtaccat cagacataaa atgtaacatt ccgttaacat
     2461 tagttagtga cccgtggtaa ccaacgttaa aatcgctcga ttttagtttg gacattaaat
     2521 tcggattccc actataatca tagcccccga agtcgatgct gttggagtac atcacatgta
     2581 agttacctaa tttagaaatt tcttctttca gagcatctaa cttgtcttgt agtgttttag
     2641 cttgaccagt taaatcagta atctgtttat ttaagctatc cattctacct ttaatttcag
     2701 ccagaaaagc atcaaaagtt tcgttatact ttcgaatcaa ttcttctaat tgcgaaacat
     2761 attcatcggc ttggccttgc gaaatgtcag acactcctag tgagaaaaaa atgatatctt
     2821 gcgtcgttaa aatttgatta tcttttctat attctacgta gcagtgttta tagtatcctg
     2881 cttcactcat aaatgttcca tcaagagaaa atgtgacttc ttcgctagtt atactagtag
     2941 cgacactatc tacgtaacgg ttagatggtg ttgttccttt taatgtaaag gttccgccac
     3001 tcgtatccat ctgcaagcca tttaaaaacg gtttaacagt caccgtaatt cctttgtcac
     3061 cttgacgagc cataatagct ttggtgtagt ttaattcttt gctgaaatct aaagccaaat
     3121 tatataaact gctagccatt tatatacctc cttgtcttcg ttttaaaaac gtttttggtc
     3181 aagcactgtg ctatcatatg ctgtatcctc ttttaatcta acatcttcat accctagtcg
     3241 atgtgccact aaattccatc taaccaatac gtttggctta ctagtttcaa tgatgaaatg
     3301 gtcaatatct tcatgagtaa cagcacacaa aactagctct gtaggtgtca catgtgtcat
     3361 atatcgactt agatttactg tctcggcaaa cataggatca atatcaacac gaactttacc
     3421 atcatcacct gtaacggctt ccccataatc agcgaaataa tattctggag tttcataagc
     3481 gtttaatagt cgttgtccat aatgttctgt tggtacggtt gagtttttag tacctctaac
     3541 agtaaaattt ttatatactt gtaccgttga ttgttcaaac ctagcaagtt ttccatcttc
     3601 ccatgaacca aaaaaacaac ctggcaacgt tagcatacca tcactagtaa atttcatagt
     3661 cctaccagct actttaaact cccatgaact gcccgcacta ccattaatgc ttaaagaact
     3721 accatcgcca tcagttatat aactagcatt gctatacctg aaattgggcg caccaaaaga
     3781 taaaaacggt ttgttattac cattatccca cgtactaaaa accaaattcc cctgtggatt
     3841 tctaatcatg aaaccaccac cagttttcat ggtgtatgat acaatacctg catcagcact
     3901 tacataatca cgtgcttcta gctccataat atctttgtta actttttttg agtaccaagt
     3961 cattttgcca ttagctatac ttgttctata atcagtgcca tcactaatta atgtagtacc
     4021 tctaatagta atccctacta tctcaccagc tgtaataaac gaggcattga atccgccatc
     4081 taacgtccat gcggtgtcat acgttccatt aatgccagtt ttagagaaac caataccagc
     4141 gttgttgatt tgcaaaacgt tccgtgcagt attcttatct ggtgtgtcca taatcaaaat
     4201 acgactaggg gcttctttag gatctaataa aacgtaacca ccattttgac cagtaatcat
     4261 atcagtttga tgatctacaa tatcattgat taaatcactg atttcgccac catttttcaa
     4321 ttgatcaatg gcatcattaa tcaaattgct gacattattc tctgtgtttt ctaagaagtt
     4381 tgttttgacg tttcctacaa ctaatttatc gtatgaattg gttagaacat taaacgtata
     4441 ttccacaatt ctcgctgaca tattcacttt taactgtgga tgatacacat ctactccgtc
     4501 acccatcgaa actttttcta gatcaacaaa tttttcatag cctctttgat gcctcaatgg
     4561 tactaattca atcgaaccac tcacttgtgg tttttgttta tctatgtttg ttttcaacca
     4621 gtctttagca gcttccctta atgtggctac atcagtcgct ttgtctttaa aatcaacaaa
     4681 agaaacatat ccagcaggat aatcatccac gtaatccgtg aaaataactt cttctggtag
     4741 agtgatctcg tcttctcctt ctgaagagct gctaatgaat ggataaactc caactaaaac
     4801 actttgagca tcaatctcta agtcaagacc agttaagttt ttagtataaa tcgctttgat
     4861 tttatgatcc gtacctagac ttttttcatg acgtaatgtg ttattatctt ttagaaactc
     4921 accatgaaat cgatctagaa tagatccctc ttttccacca aagaattcta aaaaattcgc
     4981 cttttctatc ttcacattag caagcgtatc tactaatgac gagaaagaaa actgcgaagg
     5041 gatagctggt ttcgctaaaa cttttgcgtt ttgccatgcc tgagtagcag tgatcttttc
     5101 tgttccgctg tcatatttat tcaacaccga ttttcttata tcattgaaaa taggttcagc
     5161 ttttacttct atcgtattgc ctattacaga agtttttgca taataaatcc gtagacgctg
     5221 ttttgctcga ttttcatcta cataacactg aataatacgt ccttctacaa tcaaatctgc
     5281 attagttccg tttattgaat aagtaccctg aaatatctcg gctccgttta gtttattgct
     5341 aacagtagct gttaaccagt ctgacaaagc gcctaaacct tgcgtatcat ataaatgttc
     5401 agctaaatta ttcgcgtcat ttttatcgta aatagttatt aaattatcga tcatctattt
     5461 cacctacctt aacccgttac gataaatttg tattttgctc aaaccagtac aattaaaatg
     5521 attaatatcc acttgcaacg ttggatattg catggtcttc attttgttgg accgatctaa
     5581 aatatctccg tccgattgct cttcgtagca aagcatcaaa tcactatcaa tgactacatc
     5641 agttcctgct actaagcctt cgaaactaaa cacataatca tttaagatga actggcatga
     5701 agtagctgaa ggagtgatga taatctttgg aaaactttct tctaaactat tattcagcaa
     5761 gttaaatgac tgtggtttat ctacggttat aggtacatct tcttgaactc ttgcgaatgg
     5821 tttcgcagta atatttacat cgaactctcc ccattcaaca atatcgtttt ctgcatcccc
     5881 aatatcgata gtctggataa cgtaatagac gttgggatcg tcagagaatt ctaatttctt
     5941 tgcatagttt aaccaatgac gcatgatata aaacgattgc ttgaacgctt gatggtcttc
     6001 cacatcctct aaatagttat agtgcaatgt aaacgacata tcttcaaacg agtaatcttg
     6061 tactaagcca cctaacctac ctaaaacaga agtttcaact ctctgtcttt ttggagaagg
     6121 tatggttggt ctttcagcta aagccaattt atgcaaataa tcaggaaatc catcgattat
     6181 agaatgtata caatcagtca ttttttcaca tcctttttaa tactaaaaaa acaggagaaa
     6241 tactctcctg tttaacgcca tgccgaagca ttatcatttt gaatttttgt aatgctatca
     6301 atgatttgtt gagttgtttg cttcatagta acctcatctg cgttaccatc aattgtgaaa
     6361 ttgaattcgt agttattcac aggttgaatc gtttgtgccc tagatgaaac tgatgtgcta
     6421 ctcaagatac gatcaccaat ttcttgcaaa acagatcttt tcaaaggtaa aactgcttca
     6481 ggtcctgctt caccgacacc gataatattc ggagaattaa acacactacc tttcgcatac
     6541 caatcaacac ccaacgttgg gatttttccc ttcaatggat tgaattcccc actcaattta
     6601 aaatgtggta acggaatatg tggtatcgaa atattcaaat tatcaaagat gccactgatt
     6661 ttatctctaa tccaatcaat cggagcgcta acagtctttt tgataccttc ccaaatgtta
     6721 gcaattgtac ttttaacatt attgaatatg tcggaaacaa tacctgttag attggaccaa
     6781 ccgcttgaaa ttgcattttt tccatcgttt actttagagc taatagtgct tgtaattcca
     6841 ttccaaagat tcaaagcagt gtttttgata ccgttccaaa ttccgctgat ccacgaagat
     6901 atactattcc aaacactttg aatggcactt ttagctgcgt ttatagcatt gcttatacta
     6961 ctagtcacac tattccagat atttgatgct gtagagctga ttgaattcca aattccacct
     7021 aaccaactag atacagttga ccaaatattt tgaattactg tagcagctgc ttgtaccaag
     7081 ctagtgattg tattcttgat actgttccaa atactagaag ctgttgcact aattgaattc
     7141 caaatatttg aagccgtagt actaatagat gtccatatac cattccacca tgccactact
     7201 ggatcaaata tagtatggaa tgtagttaca attccgttcc aagcgatgct tatccattgt
     7261 gtcatagtat cccaagtatt tttaaggaaa tcagaaatag gtgtccaaac agcttgccaa
     7321 gctgcgcc
//
LOCUS       DADGKS010000114         7308 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.119, whole genome shotgun sequence.
ACCESSION   DADGKS010000114 DADGKS010000000
VERSION     DADGKS010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7308
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.119"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..291
                     /locus_tag="JXV47_002693"
     CDS             <1..291
                     /locus_tag="JXV47_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1488692.1"
                     /translation="IIKQCTMAELNQTAQDFIVISTTNDQAARTILTDAGYPLEDPDK
                     IKLLKKNEELLGTVIQLLSAENVHVTDVQHLTNDLESSLLEILDSVKGEEEK"
     gene            288..1061
                     /locus_tag="JXV47_002694"
     CDS             288..1061
                     /locus_tag="JXV47_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAX1488693.1"
                     /translation="MTLLIKQELFKLIKKKSTAVLSVLLVALLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMESQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSIYLYLLAIIVTVLMKLILFPSISFTEKISTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIALFLALGYLVFKRKNV"
     gene            complement(1238..2662)
                     /locus_tag="JXV47_002695"
     CDS             complement(1238..2662)
                     /locus_tag="JXV47_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAX1488694.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNVASIVMSTIFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFINNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGFLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            2873..3319
                     /gene="nrdI"
                     /locus_tag="JXV47_002696"
     CDS             2873..3319
                     /gene="nrdI"
                     /locus_tag="JXV47_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HAX1488695.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEYEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQRFGFPFLADYELRGTPSDVTRVYQILAEKNK"
     gene            complement(3389..5371)
                     /locus_tag="JXV47_002697"
     CDS             complement(3389..5371)
                     /locus_tag="JXV47_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1488696.1"
                     /translation="MAKNELTLEELAKQIYQGAGGMGNVESIVHCMTRVRMKVINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQEMVDLAGVKLGEKLPSASATTAS
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAGTWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALATGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKAVPQASA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVISSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAADK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(5385..6281)
                     /gene="murQ"
                     /locus_tag="JXV47_002698"
     CDS             complement(5385..6281)
                     /gene="murQ"
                     /locus_tag="JXV47_002698"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAX1488697.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELPSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISEHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEAAQAKLAEANGFVKGTL"
     gene            complement(6284..>7308)
                     /locus_tag="JXV47_002699"
     CDS             complement(6284..>7308)
                     /locus_tag="JXV47_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAX1488698.1"
                     /translation="EEKKQYIRQMASNGFVGIFTSMHIPEDDVSAYQNRLIELGSEAK
                     KNKLELMVDISGEALKRAGFSLEDLTPLKAIGVTGLRMDYHISNQQIADWSHQLKISL
                     NASTITPNDIDELKEAAADFSQIEAWHNYYPRLETGLDKEWYQEKNQWLKTQGFLVQG
                     FVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIGDAGLSEHVQEQFA
                     SFQKEQTVLLHTEPVDEVFYEYILGKHTNRQDDARDVIRSADARFREIPPIPVRNTAK
                     RMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELPLINQIKAGMNYQF
                     IRKEGR"
BASE COUNT         2112 a         1618 c         1306 g         2272 t
ORIGIN      
        1 atcatcaaac aatgtacaat ggctgaattg aaccaaacag cgcaagattt catcgttatc
       61 tctacgacaa atgatcaagc tgctcgaacg atcttgacag acgctggata tcccttggaa
      121 gatcctgata aaatcaagct tctaaaaaaa aacgaagagt tattaggaac tgttatccag
      181 ttattgtctg cagaaaatgt ccatgtgaca gatgtccagc atctgacgaa tgatttggaa
      241 tcttccctat tggaaattct ggattcagta aagggggaag aagaaaaatg acgttgctta
      301 taaaacaaga attatttaaa ttgatcaaga aaaagtcaac tgctgtttta tctgttctat
      361 tagttgcttt gctcatagga acagcacttc tagccaaaaa atacacgacg atcattgatc
      421 cagttgaaat gactgctcag cttttcagtg ccacatcttg gattgtcttt atcatgattg
      481 ctgctgcaag tacgatcatt tcaatggaat cacaatatgg tacattgaaa aatctccttt
      541 atcgaaagta ttctcgagga gaaatattag taagtaaatg gatcacatta gttatttatt
      601 ctatttattt atacctttta gctattattg tcaccgtgct gatgaaactg atccttttcc
      661 cttcgatttc ctttacggag aagatttcta ctggtcagac actgatccaa agcttattca
      721 cttatacttt gggtagttat atcggtttat ggctaatttt aagtttagtg ttgatgattg
      781 cttgttttat caatagttcc ggtgcctcca tctcagcagg gatcgtcttt tattttgctt
      841 catcaatcat atctggtatc ctcatcgcac tcattcaaaa atgggagtgg atcaaatgga
      901 atccaatcag tatgctgaat ctgcaaaacc aaattggcaa cgaagagatt atgaagcaat
      961 tgactcatct ttctactaat caaatgctgt ttggcaattt agcttacatt gctttgttct
     1021 tagcattggg atacctcgta ttcaagcgaa aaaatgtatg atggttcatt aacaaagaag
     1081 ttgtgacaga agtggccagt ttcaagaaat ttcggcttat ttttagaaga agctacttct
     1141 tgaacaccat ttattcaaaa aaagaagcga tgacacgaat gttgtcaccg cttctttttt
     1201 gaataaacca caggcttcac agcctctctt tatacttcta tacgtgaagc atcccagtgg
     1261 caaataaaac cattgcgatt actccgacca tcgtcacacc gataagtaaa atcttatcta
     1321 agtggatatg ttgtacaggt tcgttttgtt ctttacgtgc tttgaggtaa aaataaatac
     1381 ctggtaagaa aagaacaaga acaagcatca cttcattaaa ggctacaact agcatggccc
     1441 atacttgaaa agcacttgct aaaaacccta ctaaaaattg gacccactct ttccgctgat
     1501 aagaaagctt catttggtac agccctaaga aaagccacgt gaagaaaatc gctgctgtac
     1561 caagtgtata agcaaagtta tatgcactgt cagtgaataa taatgaaagt aaaaagacat
     1621 tcgtacataa cgtcgtcaat acgatagcat aagttggtgc cccatttttg ttgagttttc
     1681 cccatgcttt aggcaaaagt ccgtcctcag ccatattccc cattgtttca atcggcaaga
     1741 ttgtccatga gagccaaacc ccaactaaag aaatgatcaa accgccgttg atcacgaccg
     1801 ccccccattt accaaccatc atttcaaata catatcccat agcaggttgc gctttgatcg
     1861 tttgcagctg attcatcgtc attgtgccat atggaagcat ggaaaccaag acgtaaataa
     1921 tgatcaaacc gaatattcct agaatcgttg ctttcccaac atccgattgt ttttttgctc
     1981 gtgaacctac gacagaagct ccttcaatac caacgaatac ccagagcatc accatgatgc
     2041 aactcaatac ttgactagaa aacgggatcg gctgcccatt cgcattcaat atgatatcgc
     2101 tagaaaagtt attaatgaat tgttggatcg aaaaggtgct gatagctact acaataaata
     2161 aaaataatgg cactaattta caaaatgtga cgatagcatt gacaaagcta gcattttcaa
     2221 ctccacgatt cactagccat gcatatcccc ataagaagat cgtactcatc acgatcgatg
     2281 ccacattttg accaccttcg aatacgggga agaaataacc taatgcactc atcaacaatg
     2341 ttgcgaacgc cacgtttcct aaccagcatg tgagccagta accccaaccg ctgataaaac
     2401 cagcgaaacg gccaaaacct tcttctgcgt aactaaagat cccgcctttt aaatctggac
     2461 gttttttatt gatattattg atcgataagg agagcatcaa cattgctgtt cctacgagta
     2521 cccagctgaa gatagctggg ccaccagccg atccggagat gtccgtcata ataccaaata
     2581 cgccacctcc aatcgctgaa ccaatcacta aggcagcaag tggaatcaaa ccaattcctt
     2641 ttttctgttg ctctgtatcc atgtaagcat cctccaaagt aaaaccgctt ttatcaaaaa
     2701 gtataacaaa ccttttttat ttttacttaa ttaataaaaa ctttaataga aatataattc
     2761 taccgacttt tttctcatta tacaagcaaa gcgcctagtc cctttccaaa ttacaccacc
     2821 aaaaaaactt aaaaagatgc tatactaaag ggaaagaatt gggggatgat ccatgaacat
     2881 tttatatata tcgatttcag gaaatacgcg tgcttttgcc aaacatctag cagaatatgc
     2941 tgaaaaaatg catgcagaag atcctgtcaa tcctgaagtt actttaaaag aaatccatga
     3001 aaatagtgat tttacgaaag aaacagaacc attttttact ttcgttccta cttatttaga
     3061 cggcgggaat gggttagaca acggtgacac agaaatcttg accgaaacga tgcgcgaata
     3121 tctggaatac gaagacaatc ataaactttg ccttggtgta gtcggtagcg gtaataaaaa
     3181 cttcaacaat caatattgtc tgacagccaa acaatacgca caaagattcg gctttccttt
     3241 cttggcagat tatgaattac ggggaacacc atctgatgtg acacgcgttt atcaaatttt
     3301 ggcagaaaaa aataaataac acaaaagaag aagctgaaaa ataaatttcg gcttcttctt
     3361 tttatgttct ctattgtttc tattcttatt aagctttgac atccatcaca ggtgcttttg
     3421 ctttcgcttt acctgttttt tccaagacaa agttttttac acgatccata ttggttacca
     3481 agacgatcat ggaggtttct ttgtctgctg ctttgattgc ttctaagtca gcttctgcta
     3541 caagcgtatc aggtgtcact tgctgtcctt ctgttacttt cacatcgaat ggcgtaccgc
     3601 ctaagtcaac tgtgttgatg cccatgtgaa gcaagatttc taagccattt ggtgtcgtaa
     3661 tgccgatagc atgttttgtt gggaaaacag aacttattac tccagtaacc ggggaataga
     3721 tatgtccgtt ttctggttct acaaagtaac cttcacccat cattttttgt gcaaaaactg
     3781 ggtcacttgc tttatctaaa gaaacaactg ttccgtcagc aactgatgat aagatagtca
     3841 cactttcagc tgaagcttga ggtactgctt tttcaggtac ttcatttact gtggctgttt
     3901 cggtcgctag ttcttctttt tctaaacggt ctttaggaat accgaagaag aatgtagcaa
     3961 cgaagccacc agcgtaagca gccaataaac caaggatata gcctaaccat ttaccatcag
     4021 agatcaatgg aatcaaagcg gctcctgaag gtccaatagc gattgctccg acatttccga
     4081 tcattccgat cactgcccca ccgatacctc caccgataca agcagtaata aatggacgtc
     4141 ctagaggtaa tgttactccg taaatcaatg gttcgccgat tcctaagatt ccgactggta
     4201 aagccccttt gatcatttct gttaattctt tgtctttttt gcagcggatc cataatgcca
     4261 atgctgcacc cacttgtcct gctccggcca tcgcaaggat tggaagcaat aaggtacgac
     4321 cagtttcatc aatcatttgt acatggattg gcgtcaagat ctgatgtagt ccgaacatga
     4381 ccattggcaa gaataatgta cctagaacga agccggcaaa tgctcctcca acaccaagta
     4441 cccagttgat cccaccgacc atgccgtcag aaatgaaccc tgctaaaggc atgatgaaga
     4501 aaatttcgat cagaccgatg gcaatcaggg aaagagttgg cgtaacgatg atatctaccg
     4561 catcaggtac tactttatgc agttttttct caacgattga caataaccaa actgcgaaga
     4621 taacacctaa gatcccgcct tgtccagttg caagagcttc accggtaaac aagtttttca
     4681 gtggtgcttc tggattcatc cctgtcagca tcacaacagc cccgataact ccaccaagcg
     4741 ttggcgttgc accaaaaact tgtgcagcat tgatacctgt atagataact agatagctaa
     4801 acatcccgtt tttcaagatg ttcatcacat cgatatattg ttgccatgtt cctgcgtcta
     4861 gtgttccagc tgtgactaag tttgctaaaa ctgcggcaat ccctgccacg atcccagtgc
     4921 cgacaaatgc agggatcatt ggtacaaaga tattagagat gtcttttaat accgatttga
     4981 ttttagaggg tttttgtttc gatttttgtg ccgctttcat ttcttgtgcc cgttcgttta
     5041 cacggtcttt tccagatgca gaagaacttg ctgtagttgc actagcagaa ggaagttttt
     5101 ctcctaattt cacgcctgct aagtcaacca tttcctgcgc tactttgttc actttcccag
     5161 gtccgatgat gacttggagc tgttcatcct ctactacgcc aagtactcct ggaatcgctt
     5221 ttaattccga gacatttaca agatcatcat tgatgacctt catacgtaca cgagtcatgc
     5281 agtggacaat gctttcaaca ttgcccatac cgcctgctcc ttgataaatt tgttttgcca
     5341 gttcttccaa agtcaattcg ttttttgcca tggtcttttc cccctcataa ggttcctttt
     5401 acaaaaccgt ttgcttcagc taattttgct tgagctgcct ctttatcact atttgtcaaa
     5461 atcatgacga tagccagttt gacattttga tctgcttcct caaagtactt ttcagctgtt
     5521 tcgtagtcag cttctgtcgc ttgcatgatg attcgttttg agcgttcaat tagtttttca
     5581 tttgttggtt tgacgtcgac catcaagtta ttgaatactt taccgatacc gatcatactg
     5641 atagtagaaa tcatattcaa aatcagtttt tgtgctgttc ctgacttcaa tcgagtagag
     5701 cctgtcaaaa attctggtcc tgcatcgact tcgattggga aatccgcatg ctcgctgatt
     5761 tctgcttgtt tattgcaaga aatcgttcct gtaacagcac caatcgattt tgcgtaatct
     5821 aatccaccaa tcacatatgg tgtacgaccg ctagctgcga taccaataac tatatcattt
     5881 tttgttaaat tcagcttgat tagatcttct tgccctaatt cataagaatc ttcggctcct
     5941 tcgacggcta cagtcattgc ttcttctcca ccagcaatta ggcctatgac catttccggt
     6001 tctacaccga atgtcggtac acattcagca gcatctaata caccaagtct accactcgtt
     6061 ccagctccca tataaatcaa gcgaccacct tttttaaagg attcaatcgt gttggcgatc
     6121 actggctcga tacttggcag ttctttttca acagcagcgg ccactttctg atcttctttg
     6181 ttcatgagtt ggactgcttg agaaatactc atttcatcta atccaaaagt ttcttggttt
     6241 ctgcgttccg ttgttaggtt ctctaaattg attttgctca tttttatctt ccttcttttc
     6301 ttataaattg atagttcata ccagctttga tttggttgat cagcggtagt tcttctttga
     6361 tgactttggc tactacattc actttttcat ccgctggcaa atcatattta gttaattgga
     6421 tctcacccat atagcgcaaa tacttttcgt tatctaaagt aatagatcct ttcatacgct
     6481 tagctgtatt tcttactggg attggcggaa tctctcgaaa acgcgcatct gcgcttcgta
     6541 tgacatctct tgcatcatct tgccgattcg tatgttttcc taatatatat tcgtaaaaaa
     6601 cttcatctac aggttccgta tggagcaaga ctgtctgttc tttttggaaa gaagcaaatt
     6661 gctcctgaac gtgttctgac agacctgcat ctccgatata aacaatatcc gtgttacttg
     6721 ctaatagatc aagagcacct gccagaggat ggatccctcg atgttcttcc aaagttggta
     6781 atccttgata cagtggacct ctcaactctg tatctcctgg tacaaagcct tgtacaagga
     6841 atccttgagt tttgagccat tgattttttt cctgatacca ttctttgtcc aaccctgttt
     6901 caagacgtgg ataataatta tgccaagctt caatctgtga gaaatcagcc gctgcttctt
     6961 tcaactcatc gatatcatta ggcgtgatcg tgctggcatt caaactgatt ttcaattgat
     7021 gtgaccagtc ggcgatctgc tgattagaaa tatgataatc cattcttaac cctgttacac
     7081 caattgcttt caagggtgtt agatcttcta atgaaaagcc agctcgtttc aatgcctctc
     7141 ctgaaatatc gaccatcaac tctagtttat tctttttcgc ttcgcttcct agttcgatca
     7201 atcgattttg ataagccgaa acatcatctt ccggtatatg catggaagtg aaaataccga
     7261 caaagccatt ggatgccatt tggcggatat actgtttctt ctcttctg
//
LOCUS       DADGKS010000115         7029 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.120, whole genome shotgun sequence.
ACCESSION   DADGKS010000115 DADGKS010000000
VERSION     DADGKS010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7029
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.120"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(115..681)
                     /locus_tag="JXV47_002700"
     CDS             complement(115..681)
                     /locus_tag="JXV47_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HAX1488699.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(695..1111)
                     /locus_tag="JXV47_002701"
     CDS             complement(695..1111)
                     /locus_tag="JXV47_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HAX1488700.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(1568..3502)
                     /locus_tag="JXV47_002702"
     CDS             complement(1568..3502)
                     /locus_tag="JXV47_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAX1488701.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            3804..4739
                     /locus_tag="JXV47_002703"
     CDS             3804..4739
                     /locus_tag="JXV47_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HAX1488702.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            4829..5932
                     /locus_tag="JXV47_002704"
     CDS             4829..5932
                     /locus_tag="JXV47_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HAX1488703.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            5945..6898
                     /gene="menA"
                     /locus_tag="JXV47_002705"
     CDS             5945..6898
                     /gene="menA"
                     /locus_tag="JXV47_002705"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HAX1488704.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
BASE COUNT         2178 a         1405 c         1370 g         2076 t
ORIGIN      
        1 ttcaggcgga cagtttcttc catccgtttt agtgtttctg tcaattcttt acttaaagca
       61 ggatagtttt cccacattgg atgtagcttc ataaaaaaac tccttgtgtg acgattattt
      121 tttggtaaac attgggctcc atttttgttt ggttccctgc tcataatctt tttggaatcg
      181 ttgaagtgtc tgcacatgtc gtaaaagata attcgctgcg atcccgattg caatccctga
      241 taaaatccct aaaactgaaa ggactggcaa gtacaacatg actgtccatg attgtgcaat
      301 gaaagaagcc atcaaaagct gtccgacatt atgcatgaaa ccgccggccg cactaattcc
      361 gatgatactg acacgttttg gtcctaattg cttgaccaat aacattccaa aataactaag
      421 caaagcacca ctcatactat aaaggaatgt ggaaatcgtt ccgcctagca aagtagtcag
      481 gaatagtcgt agccaaagta gtaagaagct gtcttgtttt ttcatggtaa aaatggcaac
      541 gatcgtgatt agattggcta agcctagttt tgcaccaggc gcaaaagaaa aaggataagg
      601 gatcatattt tccaataaac caatgatcac tccttgtgca acaagtagcg aaatataaat
      661 cattttttgt aatttactca tggtgtgtga aggtctaata aatcagactg tcttcgtcac
      721 ctccatctgt tgaacggact tcgatcacta atttatgtgg caaacagacg atggtttcgc
      781 catttttcgt tgcccagcct cgacgtacgc agatctggtc atcgcaatct gcttctttta
      841 tccgtactcg atcgccatct atctcgatca agttataatc tccgtgttca tctttgtaag
      901 tatatgtgtt gctctcttct ccagccatca aagggaatgt tttgatttct gtgccatcca
      961 cacgcagtac cgcttctttt tctgctgttg cggtgttttg ctgaagacca aaaatcatga
     1021 ctggtaaaaa agaaagaaca gtcaaaagca aaataataaa aacatcccaa ggtttgagca
     1081 gacttttttc agcaaattct ttaaggctca tttttgttct cctttttcca gattaactca
     1141 cccaatttta gcataaaaac aagaggttgt gacacctgtg tcttgctttg agtaataaga
     1201 acgaagaata gaaaacagct ttccatgttt tctaattctt tgggcttatt accgagaagc
     1261 agcaggtgga acaccgttta taacaagagg ttgtgacaga agtgggcaac ttcaagaaat
     1321 aagaaggaat ttacgaaaat tacttttcaa gtttttgtga aatttcggct tatttttcga
     1381 agaagctact tctggaacac cgtttataac aagaggttgt aacagaggtt gtgacacctg
     1441 tgtcttgctc atggaggctt atctcgggca tcttattcct ttaattttac ataaaaagga
     1501 ggctgtgacg gtttgtctca gcccctttct attgaaatct tgcattcaaa taacgttctt
     1561 tatctattta tttcttgccg tactgggaac ttggtctacc gtaccaccaa ttacctagtg
     1621 tacgttgtag ccatggaatt acccagcgat ccaacccaat cgcacgtccg gaaccgttca
     1681 tcaatgcgaa agcaacaaaa atgaaccaaa tgtttaccca gtaaaacatg cctgataagc
     1741 agaacgtgat caccaataca atcgttgtcg cactgcatag ccatgtgaat aatccagcaa
     1801 tcaatgctaa tgccaaggca atttcaaaga ataccatgaa tttttggaag aacattgcta
     1861 catcattgtt tggcatgatc acttgcatga tctttgtgaa ccagtctggt gacttctcaa
     1921 tcacagccat tggttcttca ccgtatgcat aactcaaacc aaaatgtgca gcttgagtcg
     1981 ctgcttctcc ggcacttgcc cctgctccgc tggcagctgt ggttgcatca ccagcagcag
     2041 aagcaccact ggcaacatct gttacattgt attcccatgt ccaagggaac acactgtttc
     2101 cagtgaacca tgatccttca ccaaaccaag tacttggttt gaacacttca ccattcccaa
     2161 tgattttttt ggaagcttca acgaaccaaa ctaaaccata gaaaatacga agtggcacac
     2221 tccataagac attgccgtaa cgagaagaat gtcctcgagt cacgttgcga tcatctttga
     2281 tatggaaaaa ctcatgcatt aaatattgga acatataata accagaacga atatcaaaga
     2341 agtatttcaa attcacgata tgtttcatta cgatagctaa aaatccgctt aaatggatct
     2401 tatcaaatag gttagctacc ccccatttgg caccaataga aaccataaat ccttgatagt
     2461 ttcctttaaa tttatgcttt tctccgcctt tgatcgaagc cacgatattc gctgcggctg
     2521 tgtgtcctgt ttgttcagca gcttgaacga tctgcggtgt cggtgttcct gggaattctt
     2581 cataaaagac taaatcacca atgatataga tgtttttatc ttcgtagcct tttgcctgca
     2641 tatattcatt ggcgatcaac cgctgtccgc gtgctgattc taatccaaag tcagcagcgt
     2701 cagaagttcc tttgacacca gctgtccaaa tcagtgtgtg agtcggaatg ttgcgtccgt
     2761 ctttcaattt gatatgatca gcagccactt ctacgattgg tgcattcaat aataattcca
     2821 cgttgtgctt acgcaaatag cgttcagctt ttgcagcatc atttcgatcc aacatattca
     2881 agatcgtcgg cattgcctct acgaccatca gtgtgatttc gtttggatct aatttataat
     2941 ctttggctag gcgatttttc cagtcgatca gttccccaat catttcaata ccggtaaatc
     3001 cagaaccaca gacaacgaaa gtcagcatgg ctttacgcag ttcatcatct ggttccaatg
     3061 cagcttttgc tactgtcttc tcaatatgtt cccgaatcct tacagaatct tcaaatgacc
     3121 aaagggtgaa tccgtgtgct ttgacaccag gtgtaccaaa gtcattcggc tctccgccca
     3181 ttccaaggat cagctgatca aaaggatagg aacctaattt ggtcttgacg atttttcgtt
     3241 ctttatcgat accgattaca gtgtctgtga caagttgtac attcttttga cgagcaaaca
     3301 aatgctgcag atcgtattgg attgcttctg gttctacacg tccgccagct acttcatgca
     3361 actcggtcat catagtatgg tacgaatgac gatcgatcag agtaattgct acatcttctt
     3421 ttttcagttt ctttgccaag tattttgtag ctgaaacacc ggcatatcct gctcctacaa
     3481 cgacaatatt ttgctttgcc attgatcatc cgctccttat agactatcta tataatgaat
     3541 atatgataat tcttttagtt tgatacttat tacacaatct ccatatatta tatagatgtt
     3601 ctgttctttt gtctaactcc ttttggattt ttttcaaatt ttaaaataaa gcgttttttc
     3661 acgaaatttg ctgaaagaaa acgtttgaaa tattacatgg gttatttatc aaaaatagtt
     3721 gacttatagg ctaaaaagat tagaatgtat aatgaatcac aaagaaaaat tgtggactag
     3781 aaatggaatg gtggggtatt aaaatgaaga aaaaacgttt tgtaactgga tttgccgtat
     3841 tagcattttc agctctagtg ttaggcgctt gcggcgcaga tgacaacgga agctcaaact
     3901 cttcttctga atcatctaca gcacaatctt cgactgcaaa aagcacaaca gaatcatctg
     3961 caaaagttgt agctggcgga gatttgcaag acggcacata taaattagaa gaaaaaaatt
     4021 attcaaatgg ttaccgtgca gtctttgaaa tggttgtaaa agacggcaaa atcactgaat
     4081 caaaatatga taacgtcaat gaaaacggcg aatcaaaaac aaaagatgca gaatacaaca
     4141 aaaacatgga agcaaaatct ggcacaaacc cagaaaaata cattcctgag ttgaatgacc
     4201 aattcttaaa agcacaaagc gcaagcggtg tggaagtcgt aactggagct actcactcat
     4261 ctgaaagctt ccaaaactac gcacaacaat tgatccaagc tgctcaagct ggtaacacag
     4321 atacaatcga aatcgacaat ggtgctgatt tgaaagacgg cacttacaag cttgaagaaa
     4381 agaactactc taacggctac cgtgtgcaat tcgaaatgac agttgctggc ggcaaagtaa
     4441 ctgaatcaaa ctttgattat atcgacaaag acggtaaatc aaaacaagat gatacagaat
     4501 ataatgaaaa tatgaaagca aaaagcggta cagaaccaaa aacttacatc cctactctga
     4561 acgacgaatt cgtcaaagca atgggcgaag aagatggctc acctgctaat gtagaagttg
     4621 ttacaggtgc tacacacagc tcacattcat tcatcatgta cgcacaacaa ttagtgaatg
     4681 cagctgaaaa aggcgacact caaacaatcg aagtagataa tatcgtaaca gaaaaataat
     4741 cacataatca tactaataaa agttggaggg tgggacgata gccagattag gcagtcgtct
     4801 cacctttcaa aatgaagaga ggaaaaagat gcggaaaaaa ctactatttt ccttaatcac
     4861 actgggcatc tcttttatgg tgctaactgg ctgcagcaac tcagcaaata aaacaaccac
     4921 tgaaagttca gcagctacca agatattgaa agatccatat tctgatgaac agttcttgtt
     4981 agggacttac gttcgtatcc gtgtgtatga tgaaggcaaa gaatcagcat tgaaacctgc
     5041 cttcgatcga gtaaaagaac ttggtgataa aatcacgatc aatcaaaaag gttctgagat
     5101 cgatgaagtg aatgagcaag ctgggatcaa accagtaaaa gtttctgatg acgtctacac
     5161 gttagtcaag cgggcctacg aatatagcca agattctcaa ggcggattcg atatggcgat
     5221 tggtgcaatc acacaattat ggcgaatcgg ttttgatgac gccagaaaac cttcccaaga
     5281 agaaatcgat caggcattga aattagtgga ttatcataag atcgaactaa atgacaaaga
     5341 aaaaactgtt tatctaaaag aaaaaggaat gatcatcgat ttaggtgcaa tcgccaaagg
     5401 ttacattacg gacgaagtag tgaaagtctt gaaaaaacaa ggagtgacca ctgccatcgt
     5461 tgacttgggc ggtaatgtct atgtcttagg ccacagccca agaggcgaaa accaagactg
     5521 gacagtcggc atccaagatc cgaacatggc tcgcggatct gttttaggtt ctattaaaga
     5581 acggaacaaa acattagtta cctctggaat ttacgagcgt tatttagaag tagatggcaa
     5641 aaaataccat catttgtttg atccaaaaac gggttatccg ttcgacaatg atatcgcaag
     5701 tgtcacgatc ataacagata aatcaattga tggtgacggg ttgtctacag cagtcttttc
     5761 aatgggtgtg aaaaaaggac tggaatacgt cgaaagcgaa ttgaataacg ggacggaagc
     5821 gatcttcgtg acaaaagacg ataaagtata tgtgaccgat ccaatcaaag acaccttcaa
     5881 attatcggag gactcccatt acacgatggg tgaccgttct gaactaaaat aaggagtacg
     5941 aaccatgaca ctaaaaatct ttttagaagt agttgaaata cgaacaaagg tggctagtgt
     6001 atttcctttt gcggtagggg tattattctc tatcgctttt tttcatgaga tacattggct
     6061 aaacactttt ttatttttta ttggaatgct agtttttgat ttagcgacta ccgctatcaa
     6121 taattacatg gattatgaaa aggctcattc tgaagtatat aagtatgaag aaaatgtcat
     6181 tggccgcaga aatctatctc ctgtattgat tcgaaacatg attttagcta tgattgcatt
     6241 tgtttttgtt atcggcgtta ttctaacgat caatacgggt tggcttttac ttttgatggg
     6301 atttatctgt tgttttattg gagtattcta tacattcgga ccgattcctt tatctcgaat
     6361 gcctttaggg gaaattttca gtggggtgac tatgggcctt ggaatttttg ccatggtcgt
     6421 ttatgtcaat acattcggtt cagatgtcta tgatctgaca gtcaactttt catctggaca
     6481 atttgctttg gtaggaaatc tttgggctat agcagcaatc gtattagctt ccttaccctt
     6541 ggtgtttacg attgccaata tcatgttggc taataatttg cgggatcttg accgtgatat
     6601 tgaaaatcat cgctatacac tagtttttta tatcggacgt cctgcgggaa cagtcttatt
     6661 ccagctattg atgtatgctt gctatttcgt gattttaatg gggttgttga gcggtatcta
     6721 tgaatggccg atcttggtca ccttcttgac cttgccaatt gtgaagaagc atttggatca
     6781 attcaagcaa acgttacccc agcctatcag tttcagctat tccatcaaaa atatggtctt
     6841 attcaatgcc agttatgtat tggggctatt actaacaatc attatgcaag ccatttaaca
     6901 gcatgaagag gttgtgaaaa aactgccctg catcaagtaa taagaacagc caaataaaaa
     6961 tagctcctta tatttttcgt ttggttgggc ttattaccgc agatgcaagc ttttgaacac
     7021 cgtttatca
//
LOCUS       DADGKS010000116         6802 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.121, whole genome shotgun sequence.
ACCESSION   DADGKS010000116 DADGKS010000000
VERSION     DADGKS010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6802
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.121"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            15..404
                     /locus_tag="JXV47_002706"
     CDS             15..404
                     /locus_tag="JXV47_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAX1488705.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLMFV
                     IVFAHVPPLSMIEGAFLKYLGIPIAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            391..2838
                     /locus_tag="JXV47_002707"
     CDS             391..2838
                     /locus_tag="JXV47_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAX1488706.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDLQTDALVSMI
                     GDSQIDYRFFIGFKLISTDEEVNLKNLRKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVKRVTPSDLTYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPTRCLIEEKPRYLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAKSVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HKEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALASAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVIVELRKEDSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDKEDESNQKCMRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            2843..4951
                     /locus_tag="JXV47_002708"
     CDS             2843..4951
                     /locus_tag="JXV47_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAX1488707.1"
                     /translation="MKKKLFRIFGIVLISLVTLIILLSLVGTVAEATGLVDDTVGAGN
                     LYSQYSLGNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEVGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMNMFNLQSNDSQSMGRRVMRKPQMLMNRTLR
                     QLNRNVGRTLAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEIPSDLNKEK
                     PIPNNKKQSRMNLAGRKVGKVLDTQALVKDKTKQVKDGVRNTPTNLKYNFHKGIEKTK
                     KAPEEFKRGLVQEKANRGELREKQQQRRDEKIAEKRKVLNEIGNPHGKRRENVPIKAK
                     VQSQKDRAPKRIVRANSNPEIKRKFASQEIISKGINQSSSKKNSFQQVKRRSTLSKRT
                     NRKVQKSLNPHPKPRSGEKK"
     gene            4948..5952
                     /locus_tag="JXV47_002709"
     CDS             4948..5952
                     /locus_tag="JXV47_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAX1488708.1"
                     /translation="MNVKKLSAISLTFLTISFMGILMCVGLLFGEDSEGSSSSGAPPG
                     GSSVSEEVLKHRAMVEKYAKESDITEYVPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNFGGGYLDYVAKNGKKHSFALA
                     ESFSKEKSCGQKIDYPNPIANKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSRPETGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTESYWQQHLIGAGRYK
                     "
     gene            5971..>6802
                     /locus_tag="JXV47_002710"
     CDS             5971..>6802
                     /locus_tag="JXV47_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAX1488709.1"
                     /translation="MKIKIERNQKEKSLKKKKERVVSVGKHRKMVLALWLLLSCSLTF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGIENFTKDFSKEYFSWKNNKEAIEKRMNNL
                     EQYLTEEGFALSQDMVRADIPTNSEVQSVKVLDVEKSSEEFVVSFLVEQKITEGKKAQ
                     SISSAYRVTIFEDENRNYIVTSLPTMIAKPDRAKYKTKQVENDSKIDAKTTEEIAEFL
                     ETFFKLYPSASEKELEYYVENDAMRPINIDLKFSKLEDPVYLQNGKKILVSTKIKYLD
                     N"
BASE COUNT         2183 a         1160 c         1517 g         1942 t
ORIGIN      
        1 ttttggagga aactatgaaa aaaataaaaa gctacaccag tatttgggca gttgaaaaag
       61 tcatttatgc gattaatgac tttcagctgc cttttcctgt gacctttaac cagatggctt
      121 ggtttgtttt atccttgatg tttgtcattg tatttgccca tgtgcctccg ctatccatga
      181 tagagggggc ttttttaaaa tacttgggca ttccgatagc ggtcacttgg ttcatgtcgc
      241 aaaagacctt tgacggtaag aaaccattgg gatttttacg atcctttatc agctatcact
      301 tacggtttaa ggtcactttt gcaggaaaga aagttaaaga acagaagaaa cgatgggacg
      361 aaccaatcac cttggtaagg agtgtgaatt atgtacccga ttaagtatat tgaaaataat
      421 cttgtcttta accaagaagg cgagtgtttt gcttactatg aattagtgcc ttacaattac
      481 tcctttttgt cacctgaaca gaagtatcaa gtacatgata actttcgcca attaattgcg
      541 caaaatcgtg aaggtaagat ccatgcctta caaattgcca cagaaagtag tattcgtgcc
      601 acacaagaac gttcgaaaaa ggaaattacc ggtagactca aagaagtagc aaagcaacga
      661 attgatttac agacagatgc attagtatcc atgattggcg atagtcagat tgattatcgc
      721 ttctttattg gctttaaact gatttcgaca gatgaagagg tcaatctaaa gaatctcagg
      781 aaatctttct tttctggact tcaagaattt gtctatggag tgaatcatca tttgatgggt
      841 gattttgttt ccttatccaa tgaagaaatt cgtcgctata ccaagcttga aaaactaatg
      901 gaaagtaaat tggctcgaag atttaaagtc aaacgagtaa cgccgagtga cttgacgtat
      961 ttaattgaac atatctatgg tgaaaaaggc acaccgtttg aagaatatga attccagcta
     1021 ccaaagaaaa agctgaaatc agaaacgctg gtgaaacgtt acgacttatt acgtcccact
     1081 cgttgtttga ttgaagaaaa gcctcggtac ttacggatgg aacatgaaaa tcatgagtct
     1141 tatgtagcgt acttaacaat taataccatt gtaggggaaa tggagtttcc ttcctcggaa
     1201 cttttctatt accagcaaca acaatttacg tttccgattg atacttcaat gaatgtggaa
     1261 attgtgacga ataaaaaggc cctagctacc gttcgtaata agaaaaagga attaaaagat
     1321 ttagacaacc atgcctatca atctgataat gaaacgaact ccaatgtatt agatgctttg
     1381 gattccgtgg atgaattgga aaccaccttg gatcagtcga aagaatccat gtataaacta
     1441 agctatgtgg ttcgagtgag tgctaaatca gtggatgaat taaaacgccg ctgtgatgaa
     1501 gtgctcgatt tttatgacga taccaatgta aaactagtcc ggccctttgg cgatatgatg
     1561 ggtctacaca aagaattctt accctcaagt aagcgataca tgaatgacta tattcaatat
     1621 gttacgtctg actttttggc gggacttggt tttggggcta ctcaaatgct aggagaatta
     1681 gaaggcattt actttggcta taacgtagat acggggcgca atgtttacct gaaaccggca
     1741 ttggcatcac aaggggtcaa aggctcagta accaatgctt tggcatctgc tttccttggt
     1801 tcgttaggtg gggggaaatc ttttagcaac aatctcttag tctattatgc cgtccttttt
     1861 ggtgggcaag ctgtgattgt cgatccaaaa ggagaaagag gcggttggaa agaaacgttg
     1921 ccagaaattg cggatgaaat taatattctt aacttgacca gtaagccaga aaatcaaggc
     1981 ttacttgatc cctatgtgat tatgaagaaa aagaaagact cagaaagttt ggcgattgat
     2041 atcctgacct ttttaacagg gatttccagt cgggatgggg agaagttccc tgtgttacgc
     2101 aaagccattc gaacggttac ccaaagtgat cagcgaggat tattacaagt aatcgttgaa
     2161 ttgcgtaaag aggactcacc agtcgcggaa aatatcgcgg atcacatcga gtcctttacc
     2221 gattatgatt ttgcccattt gcttttctca gatggttcga ttacccagtc gattagttta
     2281 gataagcagt taaatatcat tcaagtagcg gatttggttt taccagatgc agaaaccact
     2341 tttgaagaat ataccaccat ggaattgctg agtgtttcca tgctaattgt tatttccact
     2401 tttgccttgg actttatcca tagcaaccga gaaattttca agattgtgga cctggatgag
     2461 gcttggagtt ttcttcaagt agctcaagga aaaacgttat cgaataaatt agtgcgtgct
     2521 ggtcgggcca tgaatgccgg tgtttacttc gtcacgcaaa acagtgatga cttgttggat
     2581 gaacgtttga agaataatat tgggctaaag tttgcatttc gcagtaccga tattcatgaa
     2641 atcaagaaaa ccttggaatt ctttggatta gataaagaag atgaaagtaa tcaaaaatgc
     2701 atgcgagatt tggaaaatgg gcaatgcttg atgcaggatt tgtatggtcg agtaggtgtg
     2761 gtccaagttc atccagtctt tgaagaactt ttccatgctt ttgatacccg tccgccagtt
     2821 caagagagaa tggagtgagg agatgaaaaa gaaacttttt cgtatctttg gaattgtttt
     2881 aatcagtttg gtcactctga taatactttt gagcttagtt ggaacggtag ctgaggcaac
     2941 aggtctggtt gatgatacag ttggagccgg aaatctttat tcccaatatt cacttggtaa
     3001 ctatcagttg gatttctttg tggatagttc gtgggattgg ctgccttgga attggggtga
     3061 tggcctaggg aagagcgtaa tgtatggact ttatgccatt actaatttta tttggacagt
     3121 tagtctctac ttatcaaatg ccacgggcta cgtggttcaa gaagcctata agctggattt
     3181 catttcagat acggctgaaa gtattgggaa gaatatccaa accttagccg gcattaccga
     3241 aaatggactc cagacctcgg gcttttactt tgggtttcta ttattgatga ttttagctct
     3301 aggagtttat gtggcgtata caggattatt aaaacgagaa actaccaaag cagtccgggc
     3361 tgtcattaat tttgtgatga tttttctact ttcgggttcg ttcattgcgt atgcgcccac
     3421 ctatatcaca aaaatcaatg attttagctc agatgtcagc gaagcggctc ttagccttgg
     3481 aaccgagatt gtcgtgccga attcagaaag ccaaggaaag gacagtgtgg atttaatccg
     3541 agatagcttg ttttccattc aagtccaaca accgtggtta ctcttgcaat ttgatgattc
     3601 caatatagaa gaagttggcg aagatcgtgt taacaaaatc ctgtctgtaa gtccagatga
     3661 aaataaaggc aaggatcggg aagaagcggt caaagcggag attgaagata atgacaatgc
     3721 gaatctcagt attaccaaga ccatgaaccg cttagggacc gtggtctttt tggtgttgtt
     3781 caatattggc atatccttct ttgtctttct cctaacaggg attatgttgt tctcgcaaat
     3841 tctctttatt atctttgcga tgtttttgcc gattagtttc ttattgtcca tgttgccgac
     3901 ttatgagagt ttgggcaaga aggcgattat tcgcttgttc aatacgatta tgatgcgagc
     3961 aggagttact ttggtgatta cgactgcatt tagcatctcc acgatgtttt tcaatatttc
     4021 ggcaacctat ccatttttca tggttgcttt tctgcaaatt gtgacctttg ccggtatcta
     4081 tttcaaattg ggcgacatta tgaatatgtt caatctccag agtaatgata gccaatcaat
     4141 gggaagacgg gtcatgcgaa aaccgcaaat gttaatgaat cgaacattgc ggcaactcaa
     4201 tcgaaatgtg ggacggactt tggcttttgg tggtggtgca gcagttggaa ataagttggc
     4261 aaaggaacaa tcaaaatcca aatttaagcc atccggttct tctctacgaa agaattcacg
     4321 attaccgaac gatcacgaga taccatctga cttgaataag gaaaagccaa ttccaaataa
     4381 taagaaacaa tcccgaatga atttggccgg gagaaaagtc ggcaaggttc tggataccca
     4441 agctttggtg aaagataaga ccaaacaagt aaaggatgga gtacggaata cgccaaccaa
     4501 cttgaaatac aacttccata aaggaattga aaaaacgaaa aaagcaccgg aagagtttaa
     4561 gcgaggactg gtccaagaaa aagcaaatcg aggagagttg cgagaaaaac aacaacaacg
     4621 tagagacgaa aaaatagctg aaaagcgcaa agtattgaac gaaataggga atcctcatgg
     4681 gaaaagaagg gaaaatgttc cgataaaagc aaaggtccaa tctcaaaagg atagagcacc
     4741 aaagcggatt gtgagagcaa attcgaatcc cgaaatcaaa cgaaaattcg ctagccaaga
     4801 aatcatttca aaaggaataa accaatcctc aagtaagaaa aattcttttc aacaagtgaa
     4861 acggcggtct actctgtcca aacgaaccaa tcgaaaagta caaaaaagtt tgaaccctca
     4921 tcccaaacca aggtcaggtg agaaaaaatg aacgtaaaga aattaagtgc catttcgtta
     4981 actttcctaa caatctcttt tatgggtatc ttgatgtgtg tgggcttatt gtttggtgaa
     5041 gacagtgaag gaagtagtag ttcaggtgct cctcctgggg ggagtagtgt ctcagaagag
     5101 gttttgaaac accgtgcaat ggtggaaaaa tatgccaaag aatcggatat aacagagtat
     5161 gttccgattc ttttagcgat tattcaagtg gaatctggtg gcacaatgga agatgtgatg
     5221 caaagttctg agtcagccgg tttaccaccg aattcattaa gtaccgaggc atccatcaaa
     5281 caaggatgtc tctattttgc gtctttggtt aagcgttcca aagaattagg ttgtgatcaa
     5341 gatagtatca ttcaggccta taactttggc ggtggttatt tggactatgt ggcaaaaaac
     5401 gggaagaagc atagttttgc tttagctgaa tctttttcaa aggaaaaatc ttgcggtcaa
     5461 aaaatcgatt accctaatcc catcgcgaat aaggaaaatg gtggatggcg ctataactat
     5521 ggcaatatgt tttattgctt attggtgaag caatacctaa ctacaacaca gtttgacgat
     5581 aaaacagtcc aagggatttt tgacgaggcg tttaagtatg aaggaacggc ttatgtattt
     5641 ggtgggtcaa gacccgaaac aggatttgat tgtagtggct tgactcaatg gtgttatgcc
     5701 aaagttggtc tgaaacttcc tcgggtggct caagatcagt atgatgccat gacccatatt
     5761 gacctaaaag atgccaaacc aggggatttg gttttctttc attcgactta tgatgccggt
     5821 acttatgtga cccatgtcgg tatttatgca ggggagaatc gcatgtttca tgcaggagat
     5881 ccagtaggct ggacgaatct aacagaaagc tattggcagc agcatcttat cggtgctgga
     5941 cggtacaaat aagagaaaag aggaaaaaga atgaagataa aaattgaacg gaatcaaaag
     6001 gaaaagagcc taaaaaagaa aaaagaacga gtcgtatccg tgggtaagca tcgaaaaatg
     6061 gtgcttgccc tttggctttt attatcttgt agtcttactt ttggcgttta taaaaatttc
     6121 accgccattg atcaacatac aactcatgaa aaagtggtta ttaaagagaa agtagtgaat
     6181 acttctggta ttgaaaactt tacgaaggat ttttcgaaag aatatttttc gtggaaaaat
     6241 aacaaagaag caattgaaaa gagaatgaac aacctcgaac agtaccttac agaagaaggt
     6301 ttcgctttaa gtcaagatat ggttcgagca gatattccca ctaattccga agttcagtca
     6361 gtaaaagtct tagatgttga aaagagctcg gaggaatttg tcgtttcatt tttagtggag
     6421 caaaagatta cagagggaaa aaaggcacaa tcgatttctt ctgcataccg agtgacgatc
     6481 tttgaagatg aaaacaggaa ttatatagta acgagtttgc caactatgat tgcaaaacct
     6541 gatagggcaa aatacaagac aaaacaagta gaaaatgatt cgaaaattga tgccaaaact
     6601 acagaagaaa tcgctgagtt tttggaaacg ttctttaaat tatatccatc agcttctgaa
     6661 aaagaattgg agtattatgt tgaaaatgat gcgatgcgac caatcaatat tgacttaaag
     6721 ttttcgaagt tagaggatcc agtttaccta caaaacggaa aaaaaattct agtgagtaca
     6781 aagataaaat accttgataa tg
//
LOCUS       DADGKS010000117         6705 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.122, whole genome shotgun sequence.
ACCESSION   DADGKS010000117 DADGKS010000000
VERSION     DADGKS010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6705
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.122"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            144..965
                     /locus_tag="JXV47_002711"
     CDS             144..965
                     /locus_tag="JXV47_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HAX1488710.1"
                     /translation="MGLLVPRANTYTIPLTKRQLIAKRYQRITRAINREFWNSESDTA
                     HSLYVGSYGRGTAISTSDIDIIVELPMAEFDRFKNYLSNGPSKLLQVIKNAFQEILPN
                     SDIRADGQVVKINFHDGIKFEIVPAFNEKDYLGESKGFIYPDSNMGGNWKATNPKKEQ
                     EAMKLKNTKSNNLLYATCKHFRHVRDTEFTSYHLSGIVIDSFVYEAMGNWKFVENNSG
                     GQNISSVSYETALLEYYNSHKVMGGLNLYSPGSNQFVNSDSSIICLEKVLKKIAL"
     gene            985..1545
                     /locus_tag="JXV47_002712"
     CDS             985..1545
                     /locus_tag="JXV47_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLATT domain-containing protein"
                     /protein_id="HAX1488711.1"
                     /translation="MGDEKKRLEVQLREAYGRVTYTYTTHLKQADNIISDNKILRCLQ
                     IGLSALTTGGVLSTIITDNSELTFVAGLCSTISLGLNLYFKNFDLAEEAKNHQIVADK
                     LWLIREEYVSLLTDLNRLSVEDIVKKRDQLMNKTHEAYKNAPKTNSKSYESAQKALKS
                     EEEQFFTEEELDKMLPEHLRKKSSKY"
     gene            2453..3220
                     /locus_tag="JXV47_002713"
     CDS             2453..3220
                     /locus_tag="JXV47_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HAX1488712.1"
                     /translation="MRDRILEVNQEMVNKLTNISGNYEKYDGTLLDNYIFHDTQNIRI
                     GRSKPRAFILIKEKYLNEWNSTYEMVMTDNFEKVLDFRNALLGSDMGNSSLESIEVEN
                     KTENEGEGLIKNVLKIEQKYISEDRSFYRVTSSVGLANFATNLIGNNASESLLVMCLN
                     TKNEVIAYSEVFKGGINQSVAIPREIFQLALLNNSAKIAVSHNHPSGYEFPSENDKSF
                     TTNLKNAGKTIGIELLDHIIVTSKNTSYYSFQENGSL"
     gene            3246..3791
                     /locus_tag="JXV47_002714"
     CDS             3246..3791
                     /locus_tag="JXV47_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488713.1"
                     /translation="MGERTQALITVKYGNSKTKVSVSIHYQWGYGRFMLMDVLNQGIY
                     LINKAYDLRDESREELAKGIFDRSTGVINFVTYESGVSAYDETGFGGRYEPYQETIED
                     VMKFSDNNDGYAHLEMVFDENGFSLDDKTRLRLFDFEGQQIGLNKFCESGKEFATKDF
                     IKGYRLLLENYGINLEEESVK"
     gene            3792..4358
                     /locus_tag="JXV47_002715"
     CDS             3792..4358
                     /locus_tag="JXV47_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488714.1"
                     /translation="MFEKRKDQFPNLEAKSQKVIDGEMIELFQKSYGTIETTASCKYY
                     FQGKRNTFKGFADSDEELAKKIIDWLVSSEHVAREDTVRTTIEGEVLTGTRCVCCNHE
                     FVEDEGCYRINEYGDFICQSCHEIEFPTERSWFEYMLQDYEMETENGEVVFCTKEELS
                     KRSDDEIEDWCVWLVGTDDCVAYYTTAE"
     gene            4373..4621
                     /locus_tag="JXV47_002716"
     CDS             4373..4621
                     /locus_tag="JXV47_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488715.1"
                     /translation="MEGMDFIDHEDLIDFGYTWKGMVGISRSLANAFYERNYAVYVLY
                     DDNTESLVDEEYKLDLENVLYGIEKEDLAKYIFSWLGQ"
     gene            4640..4879
                     /locus_tag="JXV47_002717"
     CDS             4640..4879
                     /locus_tag="JXV47_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488716.1"
                     /translation="MTKFKSKGMQWCSYYYVGNDEELLRKAKQKGYPDKMLKQIGYYM
                     PEERIEKESCKVLFDSEQLLVLLTQNKLICQFENN"
     gene            4896..5480
                     /locus_tag="JXV47_002718"
     CDS             4896..5480
                     /locus_tag="JXV47_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488717.1"
                     /translation="MNENKMVLSEYARLRTINWLNGMQSSGAFDGFDEENMDFESLSN
                     EDIRYYFIEWYFTEPDEEVEDEPELILERQRILFSEQDSKRLYGLYDLQLKGLKAQYV
                     ADSYDDMVEQGADRVVTYSEDDEEEWENYSDDEICFNDGYMPIEITEEEYDKVSDSDE
                     IGMCTVVSGLDIDVQRVEVAYQKMKERIKSKVES"
     gene            5587..5868
                     /locus_tag="JXV47_002719"
     CDS             5587..5868
                     /locus_tag="JXV47_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HAX1488718.1"
                     /translation="MKVKNPKEKSRIQVGIDKDLKENAEMILEELGLNPTTAITILYK
                     QVVARGEFPVEIKLSEEEKQGIRLQQLTMDMPVDVLDTDEKLEEWFNEA"
     gene            5858..6199
                     /locus_tag="JXV47_002720"
     CDS             5858..6199
                     /locus_tag="JXV47_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAX1488719.1"
                     /translation="MKPNEIVTVYVAFTDKNGGKRRPILVVSDKEDRVEFFGITSQYE
                     NKSDQIKRVYFPIAEWEKVGLKKQSWIDVGSLKAIPKSRENISFKKVGMLSAIDTKKL
                     NRFIERLQRKV"
BASE COUNT         2527 a          871 c         1371 g         1936 t
ORIGIN      
        1 aatactttca attattgtga aatatttccc tttaattaat caaatttttt ataaaagtaa
       61 tatataaaat aaattgcttg aagtattata tttagatatc ataatttatg gaagaaaaat
      121 taattaaaaa ggatgagatt ataatggggt tactggttcc gagagctaat acttatacta
      181 tacctttaac gaaacgccaa ttaattgcta aaagatatca aaggattact agagccatca
      241 atagagagtt ttggaattct gaaagtgata ctgctcacag tttatacgta ggttcttatg
      301 ggagaggaac ggcaattagt actagtgata tagatataat agttgaatta ccgatggcag
      361 aatttgacag attcaaaaat tatttatcaa atggaccgtc taagttatta caagttataa
      421 aaaacgcatt tcaggaaata ctaccaaata gtgatattag agctgatgga caagttgtta
      481 aaataaattt ccatgatgga atcaaatttg aaatagttcc agcttttaat gaaaaagatt
      541 atttgggtga gtcaaaaggg tttatttatc cagattcaaa catgggaggg aactggaaag
      601 ctacaaatcc caaaaaagag caagaagcca tgaaattaaa gaatacaaaa agtaataatt
      661 tattatatgc tacgtgtaaa cattttcgac atgtacgaga tacagaattt acgagttatc
      721 atctttcagg aatagtaatt gacagtttcg tatatgaggc tatgggaaat tggaaattcg
      781 ttgaaaataa cagtgggggt caaaacatta gttctgtatc ttatgagaca gctttattag
      841 aatactataa ctcacataaa gttatgggcg gtttaaattt atactctcct ggaagcaatc
      901 aatttgttaa ttctgatagt agtatcatat gtttagaaaa agtattaaaa aaaatagctt
      961 tataaagttt tatggaggaa caacatggga gacgaaaaaa agcgcttgga agttcaatta
     1021 cgtgaagcat atggacgagt aacgtatact tacaccactc atttaaagca agccgataat
     1081 attatttctg acaataaaat tttaaggtgt cttcaaattg gtttgtcagc ccttactact
     1141 ggaggggtac ttagtaccat tattactgat aatagtgagt taacctttgt tgctggatta
     1201 tgttcaacaa tttctcttgg attaaactta tactttaaga attttgatct tgctgaagaa
     1261 gctaaaaatc atcaaattgt tgccgataaa ttatggttga tcagagaaga atacgtaagc
     1321 ttactaacag atttaaatcg tttaagtgtt gaagatattg tgaaaaaaag agatcaatta
     1381 atgaacaaaa ctcatgaagc atataaaaat gcccctaaaa caaatagtaa aagctatgaa
     1441 tcagctcaga aagcattaaa atctgaagaa gagcaatttt ttacagaaga ggaattggat
     1501 aagatgttac cagagcatct tagaaaaaag agttctaaat attgaactct ttttttatgc
     1561 ttaaaatttt cttgtaattt ttctattcaa tcaataaata atctatattt aagaagaaat
     1621 atgatgatag aaacatctcc taaagccacc gcaagccgtc ctagccattg cccagtccga
     1681 catcgctaga ttagtgcatc tctccaaaaa agttttctaa agccaccgca agccgtccta
     1741 gccattgcct agtccgacat cgctagatta gtgcatctct ccataaaagt tttctaaagc
     1801 caccgcaagc cgttctaagc atagcttagc ccgacattgc tagatatgct catctcacca
     1861 tgaacgtttc ctaaagccac cgcaaaccgt cctagccatc gcctagtgcc tagtccgatt
     1921 ttgcttgatc ggttccattt ctgtttattt agtgggtcaa caccgtaatc ttaaatagcc
     1981 atcgcctatt taagattact aggtctgctt tgaaggtaaa aagtctttca ttcttcaaga
     2041 cttttaggct ttcaagctac gcctgaaagc attgaaattc atcgctcttt atttggtttt
     2101 gccatttata attccttacg cccattatct ttttcgcctg tcataccttg tcagaagtgt
     2161 ttagagctta tctcatcttt ggattaatac aagtggcgta aatttttttc taaacgcaag
     2221 cgttacgaaa ataatttact taaacacttg tattaatccg gcagataaga acgcattcta
     2281 atcactcccg acaaggcaag acaggcgaaa aagataaata aatgaacgaa aggaagaaac
     2341 ataaaatgca aaaccaaata gcgatgaaga aaaaaccacc tccctctaaa acaatccaaa
     2401 caaaaaagaa ttttgaaaaa ccaaaaatca aaaacagaaa gaagcgttca acatgagaga
     2461 tagaatttta gaagttaatc aagaaatggt aaacaagtta acaaatatca gtgggaacta
     2521 tgaaaagtac gatggtactt tacttgataa ttatattttt cacgatacac aaaatatcag
     2581 aattggcaga agtaaaccga gagcgttcat tctcatcaaa gagaaatatt tgaatgaatg
     2641 gaatagcacc tatgaaatgg ttatgactga taactttgaa aaggtattgg atttcagaaa
     2701 tgctttgttg ggttctgata tgggaaatag cagtcttgaa tctattgaag ttgaaaacaa
     2761 gaccgagaat gaaggtgaag gattgattaa gaatgtcctg aaaatcgaac aaaaatatat
     2821 cagtgaagat agaagttttt atagagtcac aagctcggtt ggtctagcaa actttgctac
     2881 taacttaatt ggaaacaatg ctagtgaatc tttgctagtg atgtgtctga atacaaagaa
     2941 tgaggtcatt gcttatagcg aagttttcaa aggtggaatt aatcaatcag tagcgatacc
     3001 aagagagatt tttcaactag ctttgctaaa caattcagca aaaatcgcag tatcacataa
     3061 tcatccgagc ggatatgaat ttccaagtga aaatgacaaa agttttacta cgaatttgaa
     3121 aaacgcagga aaaacaattg gtattgaatt gttagaccat atcatcgtaa caagtaaaaa
     3181 cacaagctat tactcatttc aagaaaatgg ttctttataa aaattagaga aaagaggaaa
     3241 acaagatggg cgaaagaaca caagcgttaa ttacagtcaa atatggtaac agcaaaacga
     3301 aagtaagcgt gtcaattcat tatcagtggg gatatggtcg attcatgttg atggacgttt
     3361 tgaatcaagg aatatattta atcaataaag catatgactt acgagatgaa tcaagagaag
     3421 aattagcaaa aggaatcttt gatagaagta caggagttat caattttgtc acctatgaat
     3481 ctggagtgag tgcttatgat gaaacagggt ttggtgggcg ctatgaacct tatcaagaaa
     3541 cgattgaaga tgtgatgaag ttttcagata acaatgatgg ctatgctcat ttagagatgg
     3601 tgttcgatga aaatggattt agtctagatg ataaaaccag attgcgattg tttgattttg
     3661 agggtcaaca gataggacta aacaagtttt gtgaaagcgg aaaagagttt gctacgaaag
     3721 attttattaa gggatacaga ttattgctag aaaattatgg aataaaccta gaagaagaga
     3781 gcgtgaaata agtgtttgaa aaaagaaaag accagttccc taatttagaa gcgaaaagtc
     3841 aaaaagtgat tgatggtgaa atgattgaat tattccaaaa aagttatgga accatagaaa
     3901 ctaccgcaag ttgcaaatac tactttcaag gaaagagaaa cacgtttaaa ggctttgccg
     3961 attctgatga agaattggca aagaaaatca ttgattggct tgtcagcagt gaacacgtag
     4021 caagagaaga taccgttaga acaacgattg agggtgaagt cctaacaggt actagatgtg
     4081 tttgttgtaa tcatgaattt gtagaagatg aaggttgcta ccgaatcaat gaatatggtg
     4141 attttatttg ccagagttgc cacgagatag aatttccaac cgaaagaagt tggtttgaat
     4201 acatgctaca agattatgag atggaaacag aaaatggtga agtagttttt tgtaccaaag
     4261 aggaattgag taagagaagc gatgatgaaa ttgaagattg gtgtgtgtgg ttagtaggga
     4321 cagatgattg cgttgcatat tacacaacag cagaatagga gtgtgaatca gcatggaagg
     4381 aatggatttt atagatcatg aagatttgat tgattttggt tatacatgga aaggaatggt
     4441 aggtattagc agaagtcttg ctaatgcctt ttacgaaaga aattatgcag tctatgtcct
     4501 ttatgatgac aatacagaaa gccttgttga tgaagagtat aaattggatt tagagaatgt
     4561 tttatatggg atagaaaaag aagatttagc aaaatatatt ttttcatggt tgggtcaata
     4621 aacgaaagag ggtagcaaca tgacaaaatt caaaagtaaa ggtatgcaat ggtgttctta
     4681 ttattatgtt gggaatgatg aagagctttt gagaaaagcc aaacaaaaag gttatccaga
     4741 taagatgtta aaacagattg gctattacat gccagaagag agaatagaaa aagaatcttg
     4801 taaggttctt tttgatagtg aacagctatt agttttgtta actcaaaata aattgatttg
     4861 tcaatttgaa aataattaat atggggtgaa gaaccatgaa tgagaataag atggtattaa
     4921 gtgaatacgc aagattgaga accattaatt ggttgaatgg tatgcaaagt agtggcgctt
     4981 ttgatggatt tgatgaggag aatatggact ttgaaagttt atcgaatgag gatattagat
     5041 attattttat cgaatggtat tttacagaac cagatgaaga ggtggaagat gaaccagaat
     5101 taattttaga acgtcaaaga attttattca gtgaacaaga tagtaagagg ttgtatggtt
     5161 tatatgactt acaactgaaa ggattaaaag cgcagtatgt tgctgatagt tacgatgata
     5221 tggtagaaca gggggcagat agggttgtca cttattcaga agatgatgaa gaggaatggg
     5281 aaaactattc agatgatgag atatgcttta atgatgggta tatgcctatt gaaatcaccg
     5341 aagaagaata tgataaagtg tcggatagcg atgagattgg tatgtgtacg gttgtaagtg
     5401 gattggatat agatgtccaa agagtagagg ttgcatacca gaagatgaaa gaacgtataa
     5461 aaagtaaagt agaatcttga tttgattgga ttgtttgcaa agcagctaat taagagtata
     5521 atataatcat aaatgtagtt aatggatata ataatgagta tattatactc aaaagaggtg
     5581 aacgaaatga aggtaaaaaa tccaaaagaa aaaagcagaa ttcaagtcgg aatagacaag
     5641 gatttaaaag aaaacgcaga aatgatattg gaagagctag ggttaaatcc aacaacagca
     5701 atcacaatcc tttataagca agtggtcgct agaggtgagt ttccagtaga gataaagcta
     5761 agcgaagagg aaaagcaagg aatcagattg caacagctaa ctatggatat gccagttgat
     5821 gttctagata cagatgaaaa gttagaagag tggttcaatg aagcctaatg agatagtaac
     5881 ggtctatgtt gcatttacag ataaaaatgg tggtaaaaga agacctattt tggtggttag
     5941 tgataaagaa gatagagtag aattttttgg aatcacaagt caatatgaga ataaatcaga
     6001 ccaaataaag agagtgtatt ttcctattgc agaatgggaa aaagtaggtc taaagaagca
     6061 atcatggatt gacgtagggt ctttaaaggc tattcccaaa agccgagaga acatatcatt
     6121 taaaaaggtt ggtatgctat cagctattga tacgaaaaag ctaaataggt ttatcgagag
     6181 attacaaaga aaagtctaac aaggcttttc tttttttgtt tatatgtata ttaagatata
     6241 cgtttatata aacgtattta tgtatattaa aatacacgta aatatatacg tgattataaa
     6301 aattaagaaa atattaagta ttgttaaata gtgataatta gtaatatacg aattataaga
     6361 tacattttat atttaatgta tgtaaataaa taaaatgact gacggatatt gaatagtaat
     6421 aaataacaat aattcagacg gatacagtga gtgaagtagc ttgctacgaa cgaacaggca
     6481 gaatgaaacg gtagtttcat tagagcaagt cgcttgcgac gtagcgttac cactgatgta
     6541 actggcaagt tacatagaga gagtttgctt gcaaacgaac gttacccact tgaatagaaa
     6601 acaaaaataa catattagtg aattttgaat aggagccaca actcaaccaa ccgcttgcgg
     6661 tgggtgagtc ccacggagga aaagacgaac gaacggtcgc gtagc
//
LOCUS       DADGKS010000118         6644 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.123, whole genome shotgun sequence.
ACCESSION   DADGKS010000118 DADGKS010000000
VERSION     DADGKS010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6644
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.123"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(1..859)
                     /locus_tag="JXV47_002721"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="JXV47_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="JXV47_002722"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="JXV47_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HAX1488720.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="JXV47_002723"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="JXV47_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2143..2373)
                     /locus_tag="JXV47_002724"
     CDS             complement(2143..2373)
                     /locus_tag="JXV47_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HAX1488721.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(2603..3421)
                     /locus_tag="JXV47_002725"
     CDS             complement(2603..3421)
                     /locus_tag="JXV47_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAX1488722.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="JXV47_002726"
     CDS             3582..4271
                     /locus_tag="JXV47_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAX1488723.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="JXV47_002727"
     CDS             4285..5787
                     /locus_tag="JXV47_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010759843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1488724.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="JXV47_002728"
     CDS             5800..6276
                     /locus_tag="JXV47_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAX1488725.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6373..6483)
                     /locus_tag="JXV47_002729"
                     /pseudo
     CDS             complement(6373..6483)
                     /locus_tag="JXV47_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2174 a         1032 c         1203 g         2235 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttattatcca aaaataataa aaaattggag cgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt catgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt
     6421 aaagttataa aagcttcgaa atccattggc atttcgttgg aataccttga tatgattatt
     6481 caaatataaa atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg
     6541 tttactcaac ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga
     6601 accttagcac tatataccaa atatagtaaa atgctgaaag atgt
//
LOCUS       DADGKS010000119         6509 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.124, whole genome shotgun sequence.
ACCESSION   DADGKS010000119 DADGKS010000000
VERSION     DADGKS010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.124"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..300)
                     /locus_tag="JXV47_002730"
     CDS             complement(<1..300)
                     /locus_tag="JXV47_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAX1488726.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELT"
     gene            complement(318..638)
                     /locus_tag="JXV47_002731"
     CDS             complement(318..638)
                     /locus_tag="JXV47_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1488727.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            937..1713
                     /locus_tag="JXV47_002732"
     CDS             937..1713
                     /locus_tag="JXV47_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HAX1488728.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            1728..1931
                     /locus_tag="JXV47_002733"
     CDS             1728..1931
                     /locus_tag="JXV47_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1488729.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            1947..2285
                     /locus_tag="JXV47_002734"
     CDS             1947..2285
                     /locus_tag="JXV47_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HAX1488730.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            2272..2451
                     /locus_tag="JXV47_002735"
     CDS             2272..2451
                     /locus_tag="JXV47_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488731.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(2494..2964)
                     /locus_tag="JXV47_002736"
     CDS             complement(2494..2964)
                     /locus_tag="JXV47_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488732.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            3051..3749
                     /locus_tag="JXV47_002737"
     CDS             3051..3749
                     /locus_tag="JXV47_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HAX1488733.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            3927..4268
                     /locus_tag="JXV47_002738"
     CDS             3927..4268
                     /locus_tag="JXV47_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488734.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            4261..4932
                     /locus_tag="JXV47_002739"
     CDS             4261..4932
                     /locus_tag="JXV47_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HAX1488735.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            4938..5630
                     /locus_tag="JXV47_002740"
     CDS             4938..5630
                     /locus_tag="JXV47_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488736.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGGEK"
     gene            5627..6376
                     /locus_tag="JXV47_002741"
     CDS             5627..6376
                     /locus_tag="JXV47_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1488737.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
BASE COUNT         2433 a         1011 c         1252 g         1813 t
ORIGIN      
        1 agtcagttcg ttctcaatat agatatttaa taaaattaga atagctattt tatctgcttc
       61 tgtttcaaat tttgagtgaa aagttgtaga agtatcgtac aaaactgaaa attcaaaatg
      121 agaggcgctg aaatgtgcaa gttcatgaga taaatgaaag gcttctgcag tttcaccgta
      181 tagattttca ttcaaaaaaa tgattctggg ttttggatag tagaaaccag gctctttcat
      241 ctccatataa actactttca aattgtattc gctcaacatt tctttcaatt tcaaatacat
      301 acaaaccatc actccaacta ttcattttcc tctaaagctt tagcaattgc aatcgcttta
      361 cgcattgtct ccttagatat ttcttttcca tcaaaagaaa aaacagtatc gtcttctgat
      421 aaatccacat gtttaggggt ttctctttct tctctaccta gaaggtagtc tacagagaca
      481 tcgaaatagt cagcaatccg acttaattca tctgaattag gagtattatt tttccacttt
      541 gctagataac cgttagaata tccaaaatta atttctaact gccgtataga tatctttttc
      601 ctcttcgcca agtcttttat tatttcatag gtattcatcg ataaaacaac ctttctaaat
      661 gtttacaaaa aaagtttaga aaaatacgca gaaataattt gactaattct gagtaatgag
      721 ctatactata tcttgtaaac agatttaaca actaaaaaga caacaaaaaa cactattgat
      781 atgtaaatgc agaccgccaa gaaagcttta aaatcaatgt ttttatgtct tatttaatta
      841 tgctcttagt atagagtatt actcagatac tgtcaattga atttagaaaa aagttgttaa
      901 atttgtttac gaatataaaa gaaaggaatg agaaatatga acacaccgca aatttttaat
      961 ttcgaacaaa acgaagttcg gacaatttta gtaaatgatg aaccatattt tgtaggcaaa
     1021 gacgttgcga gtgttttggg ttattcaaac actaaagatg ctttgtcgcg gcatgtagat
     1081 ttggaagata agatggggtc gcgaatcacg acctcaggtc aatcaagaga gatgacaatc
     1141 atcaacgaat ctggtttgta cagtttaatc ttaaaatcaa aacttccctc tgccaaaaaa
     1201 tttaaacgtt gggtaacaag tgaagtgttg ccagcaatta gaaaacatgg aggttatcta
     1261 actccagaaa aagtagaaga agctttgctt aatccagata caatcattca attagcaact
     1321 caactaaaag aagaaagaac tggaagatta atcgcagaac aaaagattgc agagtacgaa
     1381 cctaaaatct cctatttaga tagcatatta tcttctacag attcagtaac aattagtcag
     1441 attgcagcag attatgggat gtctccacaa cagatgaata aattacttca taaactaggt
     1501 attcagaaaa aagtcggtaa ccaatggtta ttgtgcaaaa aacacatgaa ccaaggatac
     1561 acaaaatctc atacaactga gatcccgaaa gccgatggtg gcactaaaat tgtaatgaat
     1621 accaaatgga cacagaaagg gcgtctattt atctacgaat tactaaaaaa agaaggatat
     1681 taccctcaaa tggatttaga ggaaattggt tagaaaggag ttttagtatg actgacattg
     1741 cagaaatcac tcaacgagat agagaaaaaa tcaaagaata tgtcgaaagt tcaaagttct
     1801 taacttacac catgcttgct gaaagatttg gaattagcaa aagctactta tctttaattt
     1861 taaacggtaa aaagacttct gcagaagcaa acagaattat agattcgatt atcactatgt
     1921 acgaattgta aagggaggaa cagctaatgc aatatctaga agcaaaaatc ccaattccag
     1981 aaggctatgt aattatctcc caagtggatt atgaggagtt aaaaaaagct gatgatactg
     2041 gtagatggat gacgttgcca gaagtgctag aacggattaa cagaaaatat gattggttta
     2101 cttctagagt tttaaagaac ccaagatata gaaatattat cgatatcgag aaaaacaaaa
     2161 atggatttgt ctattatcca gttgaaggaa gagacacata tctattttta agaagtaaaa
     2221 cacttgaatt tttagaaaca aatttttcgg aaatcttaag gaggcaagcg gatgggaaaa
     2281 tttaatagag cgctagtgtt cagcgcaccg ctaatcatct acgctttagg actttgggga
     2341 agcaggcaag cgttgatagg aacgattgtt tacatggttt ggatttttat ggggcttgat
     2401 gaagctgaag ctgagtacag agcgaaaaag ccaaccgagg gggctgacta aaaatgaata
     2461 gaaaagagaa actagaatgt atattactat tactcagttt aattctttca ctaatttctc
     2521 tattgggaag tttgtatttt tgatatcaac aattttgtgg atttgggttc tatttagagt
     2581 aaatatcatt tttgtttggt gattaaggag tttattaaaa ttaattttcc ctacttcaaa
     2641 tgcaaggtaa caagatatag cacttttagg aggaatattt agcggtacag cttcagagta
     2701 tattctatta tcatcgactg atcctccttt agcaattaat ttcttaaatg gagtagctga
     2761 ccatctgcgg tttaagttag cggatgaaag ttctaaatta actaacatag ctggttctgt
     2821 tgaatagtta gaaatgatta cttttgtata aatcatatct gcagcgaagt aagaagcatt
     2881 aagttcaact tctagttgag ggcgcattcc ttttattttt atccctgtta aaaacgtact
     2941 caatataaaa cttattattg acatccattg aaaaattgtt aagtgaaaaa aattcaaaat
     3001 aaacaccacc agtttttaac taaattatac caaaaaggag agaagaaata atgcaagaat
     3061 tagtaatttt gaaaaataaa gaagctgtga ctacgagctt acaagtggca gaaagcttcg
     3121 agaaaaaaca tcaacatgtt ttaagagata ttgatgcact aaaaaaagat gtgtccaatt
     3181 ttggacagat gtttgtagaa ggtaatgaac cagattcata tggcagaaat cgacgagttt
     3241 tcttcattag tagagatgga tttttcttgc tggctatggg gtttacagga aagaaagcta
     3301 tctacttcaa acaaaaatac attgaagcat tcaacgaaat ggaagatgtt attcgcaaga
     3361 atactgttcc tcaaacaatt gaagatatga tgatctatca attagaagaa atgaaagatg
     3421 ttaaaaaaga tgtttccatg cttaaagata ctatgcgaat tagcggacaa caagagtttg
     3481 aaattaagca aaaaggaaat atgaaagtta tgggagttct agggggaaaa gaaagccgag
     3541 cttatgaaga aatcagcaaa aaagtattct caaaattttg gtctgaattt aaacgtacct
     3601 tttcaatccc aagatatggc gagttacctc gtaagagatt cgatgatgct gtttcattta
     3661 ttgaaatgtg gttgccagaa actgcgatcc gtatggaaat tgatcaactg aacagacaac
     3721 agagactttt tggtgatgac aatgaataga gctgaagcgc taagaatagg gacggcaatt
     3781 gctaattgct ggtggaaata ctataaacca atcatcctaa gccaacaaca tattgacaag
     3841 caaaaagcat ggcaacaaat aaaaaagtga ctccgccggc aagcaaagag tcacaaagaa
     3901 aacacatcat aaggagattt tagcatatgg aaaaagaact ttccactcta gatcaatatt
     3961 tgattgatcc tgattggggc aagccgaaaa ttgaggaaac aagtggtcga aaaatcagac
     4021 gaaatctttt gacgaatgaa gaactagctt gggatcaaga tgatttaggc aaccatgtaa
     4081 ctatttggga tcatgtttat cttatccatc tatcgaagca ttcgaataaa cctgaatata
     4141 tttacgtcat cgaagatggc ttgattgatg cgctagaaga gtacgacaga gataacttga
     4201 ttgatatctc ttattacgga ccaggtaaga aatacattgc tgaaatggag gcagaatttg
     4261 atgagtgaaa tcaaagggac aacgaacttt gaaaaacttt ttagtcgtaa gttaaataaa
     4321 attctcaaga aaaaaggaaa ttttgattat ttatcttggg ctcacgcgtg ggagattatg
     4381 aaaaagaatg atccacaggc aacggtaact attaatgagt acaaacacta cagggttgtt
     4441 tctggaactc atcaagactt tcttgttgag gaatataaac cttttcttat ggatgaaact
     4501 gggacttatg tatctgtctc agtaacggtt aaaggacaca cggaaaccga attatttcct
     4561 gttttagatt atcgaaacca accagttgtt aaaccaaatg caatgcaaat caataactca
     4621 ttgaagcgat gctttgtgaa agcattggct ctacacggac tgggattata tgtatttcaa
     4681 ggggaagata ttccaacacc acctagaatc gatacaaaga aattaaacat gctagagacg
     4741 attctagaag ctttcaatga gcagatgggt aaagatatga ccaaaacctt aatcgaatat
     4801 gttaatgagc agacagataa attagggctc ttagctgata acgttgaaac tattgaacag
     4861 ttaagctatg agcaatgtgc cttgatggag cgagcaatag cagctaagag aaaagaatta
     4921 gataagaagt gatatgagtg tttaaaccat taatcgattc atattcagcg gttctgaaaa
     4981 agttcaaagg aaaagacata agcgcaacca tcaatgagga agtgaacatt gatcgactaa
     5041 agacgatgta tgacggctac gatggtgatc gagtcattga aattcgtttt attgatccta
     5101 gacgtttcac cgtacagcaa cgaaacttca tctatgcgct gataggcgat atttttatcg
     5161 atacaggcat gccaacggac ttctggaagg aattcttcta ctttcgtttt gaaggtgtca
     5221 cagggcgcaa aataagcctg aaagacgaat cgaatacaac tgtgagtgat gccaatgtct
     5281 tagcaaatat catcttagat ttcatctttg aacatcatat tcctttcaaa gaaggctatg
     5341 agattttacc tgcgaatcaa gaatattact tctacaaatg catcacaaaa agagtctgct
     5401 gcatctgtgg caaaacagga gctgacatcg atcactttga caaagcgcta ggaagacgaa
     5461 agcgcaaaga agttgatcat gcagagtaca catttgcagc actctgcaga atccatcaca
     5521 cagagaagca caaaataggt gtgattaatt tcaaaaataa atatcaaatc aaagggatca
     5581 aattaaacca gaaaacaatc aaaaagttaa atattggagg ggaaaaatga cagaacatcg
     5641 aagttattat gcgattatac cagccaacgt aaggtacgac aaaagactta aaccaaatac
     5701 taagttgtta tacggagaga taacggcctt gtgtaatgaa agaggctttt gttgggcagg
     5761 caatgagtac tttgcagatt tatatggtgt gaataaagag accatatcgc gatgggtaag
     5821 tgatttgatt aagtttggat acttgaatcg ggaaatcatt tacaaagagg gtaccaatca
     5881 aataatcaat aggtacctac gaattaatca ataccctatt gacgaaaaac gcaatacccc
     5941 tattgacgaa aaagtcaaag ataataatac atctattaat aatacattta ataatacaaa
     6001 agaatatata agagagttac cgccttcgaa aaaatcgaag gctaagcccg tccgtcataa
     6061 atacggagag tataaaaatg ttcttttgtc agatgagcag atggagaaac tcaaaacaga
     6121 attccctaat gattaccaag agcgaatcga acgactgtca gagtattgtg aatcatctgg
     6181 taagacttat aaaaactatt tggcaactat tcgaagttgg gcaaggaaag aaaaaagtga
     6241 acctaagaac gcaagcagtg gatacaagcg cacaggaaga cgagagaagc ttcctgaatg
     6301 ggcaatcgac caagaagcct atctcaagaa aaaagcgcta gaacgagcta atagacaatc
     6361 aaaagcacca ttctaagagg tggaaaaatg aagatcgatt atctagaact aattaatgaa
     6421 atagcgaatt ataaaaaggg cgaggaatta gacgtcctga gagacgtata tgatcaactc
     6481 gaagaagctg gaattgaagg aattaagaa
//
LOCUS       DADGKS010000120         6427 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.125, whole genome shotgun sequence.
ACCESSION   DADGKS010000120 DADGKS010000000
VERSION     DADGKS010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6427
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.125"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..626)
                     /locus_tag="JXV47_002742"
     CDS             complement(<1..626)
                     /locus_tag="JXV47_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAX1488738.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTNQLFTILEDRRLYKLTQYFLRFPR"
     gene            937..1929
                     /locus_tag="JXV47_002743"
     CDS             937..1929
                     /locus_tag="JXV47_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAX1488739.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNLAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            1989..3410
                     /locus_tag="JXV47_002744"
     CDS             1989..3410
                     /locus_tag="JXV47_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HAX1488740.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            3403..4902
                     /locus_tag="JXV47_002745"
     CDS             3403..4902
                     /locus_tag="JXV47_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009224330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HAX1488741.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            4941..6335
                     /gene="uxaC"
                     /locus_tag="JXV47_002746"
     CDS             4941..6335
                     /gene="uxaC"
                     /locus_tag="JXV47_002746"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HAX1488742.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYLTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
BASE COUNT         2084 a         1201 c         1311 g         1831 t
ORIGIN      
        1 tttctaggaa agcgcaggaa gtattgagtt agtttgtaaa gtctgcgatc ttcaaggatc
       61 gtaaatagct gattggttgt cccatcaaca caaataaaac tcatggaacc agaaacagac
      121 ttcattgatt tgaactcatc catacacaac accgtcggaa ggaagttcat acgtggctgg
      181 taatgcttcg ttgcttcacg caagatccgt gtcaccgtcc catccgagac gaagtacttc
      241 ttagcgatta gtttacgtga ttgattttcg tacagttcca tgagaatcgc ctgcttcagt
      301 tcctttgtta gttgatgatg ttcatcaact aagtccgttt tcgcagaaaa ggtccgtcca
      361 caatcatggc agagaaaacg ggtacgtttt aattctaaaa tagtcaactt ttctttgact
      421 ttcaacatct gagtgcgtgt cgtataggaa ccgttgcgga taatacgaat cgatccacag
      481 tgttcacaat gggaaggtga gtcatccaat ctccctttaa taaactgcgc ttgaacgcct
      541 ttatattctt tttcaatcag ccattcttca tcaaaaaata aatgtttatc tgttaatccg
      601 agtaattttc tagtatgatt atccattgag agactccttt ggtagggtga cgttttggtc
      661 gactaaattt taccaaaagt gagtctcttt ttgagttgaa acgaagaaaa aagtgttagt
      721 agaaaatcgc tttcgatttt ccaccaacac aaaatattat agaaccctaa ttaaatgagc
      781 attccccgct ttcaagaata gcataattaa aaataaaaat ccaagtaatt tttaacgtgt
      841 gcaatctttt catatcaaag atctattgac ttatcgtagt tatcgtaata tgatgaatgc
      901 gttaacaaaa agtgaaaaag taaggaaaat gatggaatgg taacgatcaa agatatcgct
      961 aaagcagctg gcgtttctca tacgacagtt tctcgtgctt tgaataacag cagtttaata
     1021 aaaaatgaaa caaaacaaaa aatacgacaa ctagctaagg aaatgaatta ttcgccaaac
     1081 tatagtgcaa aaggtttagt gaatcaaaaa aaatatctaa tcggactatt tttctcaagt
     1141 ttgcataaag gaacttcatc aaatttccta gcagattcca ttgcaggcat ccattcagta
     1201 ttagacacaa attacagttt atctgttgaa agtatcgatg ttgttgattt aacagaaatc
     1261 aacctgcaac gctacgatgg actgatcgtt atgagtcaaa gtgatgatga tcagcctttc
     1321 atcgactatc tcaaagaaaa agaatttcct ttcgttgttg tcaatcgtca catcaatgat
     1381 ccagcggtta tcaacgtcac tgccgatgat gcggccggtg ttatgcaggc agtagattac
     1441 ggtattggat gcggacatac gaagatcgct tatattggcg gaaagaaaaa ttttcgttcg
     1501 acaaaagaac gggaaaaagg ggtattgaaa agtctaaaaa aagcgagcat ccctgtcaat
     1561 ctagcctatt ttttaacagg agattacagc ttagaaagcg gcctccaaaa catggaatac
     1621 ctattatcac tttctgacct gcctactctg gttttttgcg gcaacgacga catagcgatt
     1681 ggtgcattga gagctgtaca tttagctggc ctccgtgttc cccagaacat ttctctgatc
     1741 gggttcgatg attctccagt cgtctcctat ctcaatccgc cgcttaccac cgtacgtaag
     1801 cctttgaaag aaatgtgtca agaaggaaca aagcttttac tagatttgat cgaaggcagg
     1861 acgatcgaac aatctaaaat tgagctctcc accttgttga tccttcgtga gtcgatcaat
     1921 tacttgtaaa ctacaagtaa ttttatataa aaatgttaac gtgtgcataa cacagaaagg
     1981 aagtttatat gaaaaaactg acaaaagaat tagtgaaaaa aaacgaagca cctgtaaaag
     2041 ttcttcagtt tggtgaaggc aattttatgc gtggatttat tgattggcag attcagcagc
     2101 tgaataacca acaattgttt aaaggtaatg ttgcaatcat tcaaccttta gaacaaggtc
     2161 ttggaaatat gatgaaccag caagataatt tatatacggt cattttacaa ggactcagca
     2221 atggcgaaat cgttgatact tccgagatta tcaccgtagt agaacaaatg atcaatcctt
     2281 atgatgaatg ggatgcttat ctatctctag cagaaaatga cgacttggcc tatatcgtct
     2341 ccaatacaac agaggcagga atccaattcg tggagactga taatttaaca gatactcccc
     2401 cacagagctt cccgggcaaa ctgacagcct ttttataccg acgtttcaaa ttaaacaaag
     2461 ctggctttac catcattcct tgcgaactga ttgacagaaa cggcgaacgt ctaaaagaaa
     2521 tcattttacg ctacgcagaa aaatgggatt tagaacctgc ttttgttgag tggttagaaa
     2581 aagaaaatgt tttctgttgt agtttagttg atcgcatcgt cccaggttat cctcgcgaag
     2641 atgcaggtgt tttcaatcaa cggcataact atgaagatca attgatggtc aaagcagaac
     2701 cattcatgct ttgggtgatc gaagggccta aagaattgga gaatcaacta ccattcaaac
     2761 aggctggctt gaatgtcatc atcacagatg atatgactcc ttatcgtgaa cgtaaggtgc
     2821 atttgcttaa tggaccgcat acagcgatgg tccctcttgc tttgttggcg gaattggaaa
     2881 ctgtagaaga agtaatgaaa gatcctttat tctccgcata tgttgatcag ttattcaatc
     2941 tagaattgat tcctatgctt tctttaccta aagatgaatt agccatttat gctgaccaaa
     3001 tcaaagaacg tttcttgaat ccttttgccc atcacaaatt agaagcgatt tcattaaata
     3061 gtgtttcaaa gttcagcacc cgtctgcttc cagtgttcaa gaagtatatc gaagaacaaa
     3121 atcaggtacc accgttaatc actgtttcac tagctgcgct acttcttatg tatcgaggcg
     3181 atcaagtaaa gccacatgat gatgaaaaga cgataagcga atttactgat gcttggtctg
     3241 ataatggaac agctattcct cgattattgc aaaacgctgc gctttgggga gaagatttgt
     3301 ctcaaatacc gaatgtgaca gatacagttc aagaaatagc tgcaaagatc gatcaaaaag
     3361 gtgtccggtc agtattacaa gaaatgaaag gaacgatggt ccatgcttga aaccctgcaa
     3421 ccaacaatga aattaaatcg acgagacagt gtggtcgtcg cattaacccc tattccaaaa
     3481 caaacacaac tgacgattga tcagcaaacg atcaccactc ttgaagatat cccgcaaggt
     3541 cataagattg cattgggtga tttgaaagct ggagacaacg tgatcaaata tggctatcca
     3601 atcggtcatg tgacgacaga cgtaactgcc ggtcaatggc tgcacactca taatgtaaaa
     3661 accaatcttt ctggtgaatt ggattatcga tatgaaaaag atgtccatcc aagtcattac
     3721 ctttttgaga accgaacatt tcaaggttac ttgcgaaaaa atggaaaagt agggattcgt
     3781 aatgatttgt ttttagtacc taccgttggg tgtgtgaatg gcattgctga actgatcgtc
     3841 aaacagttca aggaaaaaca tccagatctg ggacagtttg accatattac gattttaaag
     3901 catccttatg gctgttcgca gcttggaaaa gatcatcaaa atactcgaga aattttagcg
     3961 gacgcagtaa atcatcccaa tgccggagga gttttagtat ttggattagg ttgtgagaac
     4021 aatacagttc ctgaattcaa aaaaatttta ggtgaatatg atgaagaacg agtgaaattt
     4081 ctagtggctc aagatgttta cgatgagatc gaacaaggtg tggctctatt agaagagctt
     4141 ttaacagcgg cggaaaatga ccagcgcata tcagtcccgc tctctaagtt gaatgtcggt
     4201 ttgaaatgcg gcggttctga tggtctatcg ggaataactg ctaatccttt acttggtgca
     4261 ttttctgact acttgattgc tcaaggaggc agcacgatct taacagaagt gccagaaatg
     4321 tttggcgcag aacaagtatt gatggcacga gcggaaaatg aagaagtttt tgactcaatc
     4381 gttgacttga tcaatgactt caaacagtat ttcttgtctt acggggaacc agtttacgaa
     4441 aacccatctc ctggtaataa agcaggtggg atcactacat tagaagataa gtctttaggc
     4501 tgcacgcaaa aatcaggaag ctctcctgtc gttgatgtgc tacaatatgg cgaaaaaatc
     4561 agaaaaccag ggcttagttt attgcaagct cccgggaatg atcttgtagc tgcctctgct
     4621 cttgcttcat ccgattgcca gttggtcttg tttaccacag gaagagggac tccgtttggc
     4681 tcatatgtcc caacggtcaa ggtatctacg aatacaactc tttttgaacg caaaggtcat
     4741 tggatggatt ttaatgcagg cgtcttatta gaacaaccaa tggaagtaat cttagaatcg
     4801 tttgttcaaa aaatcatcgc tgtagctagt ggagaagaaa cgaaaaatga acaaaatgac
     4861 gttcgagaaa ttgccatttt taaaaacgga gtaacacttt gattttcata aaacagtata
     4921 aaaagaaaga aggaagattt atgtttttat ctgatgattt tttattaaaa gacgattggg
     4981 cgaaaaagct ttaccattcc tacgcaaaaa acatgcccat tattgattat cactgtcact
     5041 tagatccaaa agaaatttac gaaaacaaca atttcagcaa tctgacagaa gcttggttag
     5101 gaggcgatca ttacaaatgg cgcttgatgc gagcttgcgg cgtgcctgaa gaaaaaatca
     5161 caggaaatgc ttctgatttt gaaaaatttt tagcttggtg tcaaaccgta ccaaaaatta
     5221 tcggaaatcc gctttacagt tggtcacatc ttgaattgaa gcgtttcttc ggtattgact
     5281 tgttgataaa tgaagaaaat gcagagaaaa tttggacaca agcaaatgaa attttggcag
     5341 ctcctgattt tcgccgtcgg gaaatcgcaa aaaaatcgaa tgtagaagtg atttgtacaa
     5401 cagatgatcc cgcagacgac ttgcactatc atcagttgct tgctcatgaa gaaccagatt
     5461 tgaaggttct accttcattc cgtccagata aagcactcaa tattgaaaaa gaaggattta
     5521 atgcatgggt cacactactg gaagaagcag ctgaccaaac gatcaccacc tatcaagaac
     5581 tgatagaagt cttagggcag cggatagaat acttccatca acatggatgt cgtgtttccg
     5641 accacgcttt agacatctta cgctataaag aagcggatga aacagtatta gaagagattt
     5701 ttcaaaaagc acgagctaac aaactattat cttcagatga aatcgatgct tatcttacag
     5761 aaacactgat acatttgacc cacttctatc attctcataa ttggacgatg cagctgcaca
     5821 tccatgctta tcgtaactgt aatacacaaa tgttggaaaa attagggccc gataccggct
     5881 atgatggaat gaatgatctt tctttgacta ttcctctgca aaaattattg aaccgtgcag
     5941 aagaaacgga tcagttgcca aagacgatcc tttattcatt gaatccgaat gactatcctg
     6001 cgattttagc tttgatgggc tgtttccaaa aagaacagaa tggaaaactg cagttaggtt
     6061 ctggatggtg gtacaacgat actcgagctg gtatgcgcga tcaattgaca caatttgctg
     6121 atggtagtgc tttggggaat tttgtcggca tgctgacaga ttcaagaagt ttcctgtcct
     6181 acactagaca tgaatatttc cgtcgtgttc tttgtgaatt tttaggcgaa atggtcatgc
     6241 gaggagaagc acctgaagat gaacaacttt taggaagtct agttcaagcg attagttata
     6301 caaatgctaa aaattacttt ggcttttttg cctaattgat taatagtaac agtaacgaat
     6361 caaaaacagg atagtgaaat aacggaatcc gtttatccac gttttagaga agaagacgga
     6421 ccaaatt
//
LOCUS       DADGKS010000121         6380 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.126, whole genome shotgun sequence.
ACCESSION   DADGKS010000121 DADGKS010000000
VERSION     DADGKS010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6380
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.126"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(46..777)
                     /locus_tag="JXV47_002747"
     CDS             complement(46..777)
                     /locus_tag="JXV47_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HAX1488743.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKYPRTKFQNFQLILGSLVIFFSLVNSPALWMMVVLAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMVQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAIISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKICSS
                     DYDENPRRLKIITNTLVGDIEVIRI"
     gene            complement(945..1424)
                     /gene="greA"
                     /locus_tag="JXV47_002748"
     CDS             complement(945..1424)
                     /gene="greA"
                     /locus_tag="JXV47_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HAX1488744.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGD
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(1560..2735)
                     /gene="mltG"
                     /locus_tag="JXV47_002749"
     CDS             complement(1560..2735)
                     /gene="mltG"
                     /locus_tag="JXV47_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HAX1488745.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELYQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVQKYVNNS"
     gene            2900..4060
                     /locus_tag="JXV47_002750"
     CDS             2900..4060
                     /locus_tag="JXV47_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAX1488746.1"
                     /translation="MAKGKHQKKQQISLSFLAVLLLAVSFFSTGIITGWQLTKQPQPQ
                     IYKTEPAQLASNLTSNEQMLASKIDQLLQKSDYIGSIYVRKNNRVILEKGYGYANLRI
                     KESNSPSLYYQIGSIQKAMTALLILKQIQSGKITFDTKLSEFYPQIPGSQQISIKNML
                     YMRSGLHRTASPKKPMSDSEIIQFALHHLKFTGYDTYHYEPLNYTLLTGVLIKLMNQP
                     YETLLKKEIIRPLHLEHTDFYENVKNSPQHAVSYQMSATDDYSKALVEPETDIRNELG
                     TGNISMSVYDLNKFFTSVLSGDIIPKELLFSLWQNNGDKHPYSGGVYSGNDYILAQGN
                     INRFHAVAAMKKDTKDAIVMESNIQSDKNIKLPATDLRNQIYELMEGVNLKS"
     gene            complement(4100..5047)
                     /locus_tag="JXV47_002751"
     CDS             complement(4100..5047)
                     /locus_tag="JXV47_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAX1488747.1"
                     /translation="MLNYLITGGAGFIGSTLANYLGKENNVVVIDDLSMGKKENLDES
                     KHITFIEGDVADKNLMEKVMKEYHFDYIFHLAAVASVADSVERPLETHRVNFDSALLL
                     LELVRKYQSGLKRLVFSSSAAVYGDEPTLPKKEESVIRPLTPYAIDKFAAEQYVLDYC
                     HLYDVPTSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQLAGEKTEFTLFGDGSQSR
                     DFVYIEDVIQALLLVAKEEKALGQQFNVGTGKSTTLLELIHSIDQILGTELALKYEAE
                     RSGDIRDSLADISKIRSLGYQPKFDILNGMERYLKTEID"
     gene            complement(5080..>6380)
                     /locus_tag="JXV47_002752"
     CDS             complement(5080..>6380)
                     /locus_tag="JXV47_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HAX1488748.1"
                     /translation="SIFFKLIGISGVLLLGIDFIIKFNKRKVTYNILLIAYMVILVIT
                     SFVHKEYGLGENLKTIMWAILQYFLIYQFAFENSDNKRFFKRISWGFIYSWFVLVSMS
                     MVLFFGKFGYEKYYNARHRIRIGFLESRLFGTFSDINNAAIASLVVIVLILFYLYNKK
                     VTGLNKIIFLINLPLQFIYIVLSGSRSTYVVSIIIVAISSFIVVLKRNGTKKDLKNYI
                     LAIVSSIGSVLILFALFNATKILFQELLPHLKEINFFNFTERHKELMNNSQHINNTQT
                     PDNTLVRKDVAENTDISNARITIWKSAWEIFKTSWLIGVSPKNVVSYAQSIIPDGYIA
                     KVGIAIHNAYLNVLTSTGILGIIPFMAFLIKSFVLNVYRIIYNKCIGKDYHFVYCLVI
                     LSYALYAALNNELVYENTVGTFVFWLFLGRVNSKNNSSYF"
BASE COUNT         2060 a         1251 c          949 g         2120 t
ORIGIN      
        1 caatccccga ataaacagct agcattgctt tggatattct tcccatcata ttcgtatcac
       61 ctcgatatct ccaaccaaag tattggtaat gatcttcaat ctgcgaggat tttcatcata
      121 atcactgctg cagattttga tctgttcgtt ttttaaggaa aactgctctt cttcaaacaa
      181 gacatttcct actaatgtcg catgctctaa acgaatagcc actcccaggg gtactaagat
      241 ccgtgttctg cctatccctt ttcttacaat cacaatatta tcatcttttg gcaaaagtgt
      301 attgcccaaa tcgatgatag tatcaccaga aatgatggca atgttgatat catcccattc
      361 atagacgtcg tttccaatac gttggttacc aaataattgc tgtcttttac gctcattatt
      421 atgtgttttt aattgctctg tttggaccat catgatctgt ttttttcgcc aaaaagcatt
      481 ttttgtcaaa tctattcctg aaatctctac acctttcagc ccgataaata aaacggccaa
      541 tacaaccatc atccataaag caggactgtt gactaagcta aaaaaaatga ccaagctccc
      601 taagatcaat tgaaaatttt gaaatttagt acgaggatat ttgcgcatag ctagatatat
      661 attgaaaata ccgaatatta ctaaaagcaa aagtccagta ttgtttacga tttgccaaac
      721 agcaaataac agcagcagtg cttcgactac cacaaaaaaa cgccaagaac tattcatcgc
      781 tttttctccc tcctgacaca ttctcatttc atcataccta tttttttgac tgttggctat
      841 aggactttag atgtaagatc gttcagtgaa acctgcaata ctcaaagaga aaagatctag
      901 agtgcgtcat cagtaagatg aactctctag atctttcagt cagactacgc ttgttctact
      961 ttgacgattt taactaacat atcgccacct ggtgtagcaa tggttacttc atcattttta
     1021 cgtttgccaa tcaatgcttg cgcgatagga gaatcattgg aaatctttcc agaaaacggg
     1081 tctgcttcag cacttccgac aatcgtgtac tcttcttcat ctccatcagg caactcgatg
     1141 aacgtaactg ttttaccgat cgatacctca tctgcatcta cgccgtcatt atcgatgatt
     1201 tgtgcaaaac ggatcatatt ttcaattgtt gtgattcttc cttcaacaaa tgcttgttca
     1261 tctttagctg attcgtattc ggagttttcg gaaagatctc cgaaaccgcg agcgattttg
     1321 attcgttcaa tgatttctcc gcgtttaact gtttttagtt cttctaattc tttttctaat
     1381 ttttctttac cttctagagt cattggataa actttctcta ccatgtgtaa cgtctccttt
     1441 tttcgataaa ataccgcaaa aggtaatctt ttgaggaata tagtccaaaa aagattacca
     1501 cgcttttctt aaaatgtaaa tgtttttcta aaaatgatca atgactagcc cctgtttttc
     1561 taagaattat ttacatattt ttgcactagt tccatatgtt cttcatacgt tttagcgaaa
     1621 taaacatttc cagtgctcgt atctgctacg aaataataat agtcattttc tgctggttct
     1681 aatactgcct tgattgcctc ttcgcttgga ttgtcaaaag gaccaggccc atagccggta
     1741 ttggtataca aattgtatgg tgaatctaca gctgtatctt catacgtcac caattcttta
     1801 tgttctccta atgcatataa aacagagata tctgactgaa gtggcatatt tgccttgatt
     1861 cggttaaaga agacttgtgc aatattttta cgatcatttt cttttacgcc ttctttttca
     1921 actagagaag ccaaagttaa aacttcttgt acagtcaaat ttttctgttt gatagctgaa
     1981 taatagtttt gcatgaccgt atttgttttg ttcaccatct caatcacaag atccttaagc
     2041 gaagtactcg tgtagtaatc ataagtagct gggaataagt agccttccaa acggtatttt
     2101 gtgttctcag ctttagaggc actttccaac aattctggga atttttgata caactcgtta
     2161 aagaaagtct catcatttac taaatctaaa aattctttct tgtctttacc agttaccttc
     2221 gctacccgct cagcaatctg atcgatgtcg tagccttctg gaatggcaat tttcccatct
     2281 gcaacttttg ttggctcaga tgtgccgcct tcttgcaact gcttgccaat ctcatcaaga
     2341 gtcatattag gcgctaactg ataataacca gcttgaaagc cagttaagtt tttaaatttt
     2401 gtataataat tgaaaacaat cccactttta ataatattgt ctttctccaa aatttcgcca
     2461 atctgcttat tagaagagcc gcttgggatt tccacttgga ctaattggtc gtccgattta
     2521 tctaaaggct tcaacccgct atctacataa cgatatacgg taaacccgag aaatccgcca
     2581 ataatcaata atgtaagagc gatcactaaa atgatcttcc tcacgatctt atcttctttt
     2641 ttacgcagat ttctccgctt gtcgattata tctgctgtag ctgccttact ggcttctttt
     2701 ttgtctttgc ttgggtgttg tttgtttcct gacaaaacaa ctcctcctta ctatcatctt
     2761 cgtaactctg tttattatac atgaaatttc tactgccgtg aattatttta ccaaatatta
     2821 tgtcaaaatt gtaagtggca aatgctcttt ttgaggatta caatgaaaaa tagttaaaaa
     2881 tggataggaa ggatttaata tggcaaaagg aaaacatcaa aaaaaacagc agatctctct
     2941 ttcttttctc gcagttttgt tgctggctgt cagcttcttt tcaacaggca tcattacagg
     3001 atggcaatta acaaaacaac ctcaaccaca aatttataaa acggaacccg cacaacttgc
     3061 ttccaattta acatctaatg agcagatgct tgccagcaaa attgatcaat tactgcaaaa
     3121 atcagattat atcggttcga tttatgtacg caaaaataat cgagtgatat tagaaaaagg
     3181 atatgggtac gcaaatctac gcataaaaga atcgaattct ccttctcttt actatcaaat
     3241 cggttcgatc caaaaagcga tgactgcttt acttatccta aaacaaattc aatctggcaa
     3301 gataactttt gacacaaagc tatctgaatt ttatcctcag attcctggaa gtcagcaaat
     3361 ctcaatcaaa aatatgcttt acatgcgctc tggtcttcat cgaaccgctt ctccaaaaaa
     3421 acctatgtca gatagtgaga tcattcagtt tgcccttcat catttgaaat ttactggtta
     3481 tgatacgtat cattatgaac cattaaatta tacattgctt acaggggtat tgatcaaact
     3541 aatgaatcag ccttatgaaa ctcttttaaa aaaagaaatc attcggccac tccatctaga
     3601 acatacagat ttttatgaaa atgtaaaaaa ttcccctcag catgctgtat cttaccaaat
     3661 gtctgcaact gacgattatt caaaagcatt ggtcgagcct gaaacagaca tccgaaatga
     3721 attaggcaca ggaaatataa gtatgtctgt ttatgacttg aacaaattct ttaccagtgt
     3781 tctgtctggc gatattatac caaaagaact acttttctca ttgtggcaaa ataatggtga
     3841 taaacatcct tacagcggcg gtgtttacag tggaaatgat tatatccttg ctcagggaaa
     3901 tatcaatcga ttccatgcag tagcggcgat gaaaaaagac acaaaagatg caatcgtcat
     3961 ggaaagtaat atccaatctg ataaaaacat caaattgccg gccactgatt taagaaatca
     4021 gatttacgaa ctgatggaag gtgttaattt aaaaagctaa gtcgagacaa aaaaaccagc
     4081 aggatgctgg ttttttgttt caatcgattt ctgtctttaa ataacgttcc attccgttca
     4141 atatatcaaa tttgggttga taacctaaag aacggatctt tgaaatatcc gctaaagaat
     4201 cacgaatatc ccctgaacgc tccgcttcat atttaagcgc tagctctgtt cctaagattt
     4261 gatcaattga atgaatcaat tcaagtagcg tagtgctttt tcctgtaccg acattgaatt
     4321 gctgtcctaa agctttttct tccttagcaa caagtaaaag tgcttgtata acatcttcta
     4381 tataaacgaa gtctctagat tggctaccat caccaaataa agtaaattct gttttttctc
     4441 ctgccaattg ttttttgtat cggtccacta gaatcgaaat aactccgcta tatggagagt
     4501 taggattttg atttggacca taaacgttaa aaaatcggac agcactagtc ggaacatcat
     4561 ataaatgaca gtaatccaaa acatattgtt ctgctgcaaa cttatcgatg gcatatggtg
     4621 ttaaaggacg gatgaccgat tcttcttttt ttggcaacgt tggttcatcg ccataaactg
     4681 cagctgatga actaaatacc aatcgtttta aaccagattg atattttcgt accaattcaa
     4741 gcaataaaag cgcactgtca aaatttacac gatgagtttc tagaggacgt tctacagaat
     4801 ctgccacact agctacagca gctagatgga aaatataatc gaaatggtat tctttcatga
     4861 ccttttccat caaatttttg tcagcgacat ccccttcaat aaacgtgatg tgcttcgatt
     4921 catccagatt ctcttttttc cccatcgata aatcatcgat cacaactaca ttgttttctt
     4981 ttcctagata attcgcgagc gtcgagccaa tgaagccggc gccaccggta atcaagtaat
     5041 tcaacatttt ttctcctctt ttcaagataa aatttattac taaaaatagc tagaattatt
     5101 tttgctatta actcttccta aaaatagcca aaaaacaaac gttcctacag tgttttcata
     5161 gactaattca ttgttaagag ctgcgtatag tgcataagat aaaataacta aacagtaaac
     5221 aaaatgataa tctttaccaa tgcatttatt atagatgatt cgataaacat tcagcacaaa
     5281 actctttatt aaaaaagcca tgaaaggaat tattcctaga atacctgtcg atgttaatac
     5341 attcaagtat gcattatgaa tggcaattcc tactttcgca atatatccat ctggaataat
     5401 tgactgtgca taagatacta catttttcgg agagactccg ataagccaac ttgttttaaa
     5461 tatttcccat gcacttttcc atatagtaat tctagcatta gaaatatctg tattttcagc
     5521 tacgtctttc ctaacaagag tattatcagg tgtttgagta ttattaatat gttgactatt
     5581 attcattaat tctttatgac gctctgtaaa attaaaaaaa tttatttctt ttaaatgagg
     5641 taataattct tgaaaaagta tcttagttgc attaaacaaa gcgaataaaa tcagaacaga
     5701 accaatagaa gatactatag caaggatata gttttttaaa tctttttttg ttccatttcg
     5761 ttttaacaca acaataaaag atgatatggc aactattatt atacttacca cataggtaga
     5821 tcgtgaccca cttaatacta tataaataaa ttgtaatgga agattaatta aaaaaatgat
     5881 tttatttaat cctgtcactt ttttattata aagataaaat aagattagga caataacaac
     5941 taaagatgct atagcagcat tgttaatatc agaaaacgtc ccaaacagtc ttgattctaa
     6001 aaaaccaatt ctgatcctat gtctagcatt ataatatttc tcatagccga atttaccaaa
     6061 gaaaagaacc attgacattg atactaaaac aaaccaacta taaataaatc cccaacttat
     6121 ccttttaaaa aatcgtttat tatcgctatt ctcaaaagca aactgataaa tcaaaaaata
     6181 ctgtaagatt gcccacatta tagtctttaa gttttctcct agaccatatt ctttatgaac
     6241 aaaactcgtt attactaaaa tcaccatata tgctatcaat aaaatgttat aagttacttt
     6301 tcttttatta aatttaatta tgaaatctat ccctaatagc aaaactcctg aaattcctat
     6361 aagtttaaaa aaaatactat
//
LOCUS       DADGKS010000122         6377 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.127, whole genome shotgun sequence.
ACCESSION   DADGKS010000122 DADGKS010000000
VERSION     DADGKS010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6377
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.127"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            320..1165
                     /locus_tag="JXV47_002753"
     CDS             320..1165
                     /locus_tag="JXV47_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAX1488749.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1446..2666
                     /locus_tag="JXV47_002754"
     CDS             1446..2666
                     /locus_tag="JXV47_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HAX1488750.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2663..5383
                     /locus_tag="JXV47_002755"
     CDS             2663..5383
                     /locus_tag="JXV47_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAX1488751.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5367..6311
                     /locus_tag="JXV47_002756"
     CDS             5367..6311
                     /locus_tag="JXV47_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAX1488752.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
BASE COUNT         2372 a          986 c         1229 g         1790 t
ORIGIN      
        1 gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt gaactaatag
       61 agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat agttggttat
      121 tataaaatag taatatagct gatttggatt caattcatat ttatttataa atcaaaaata
      181 cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta cttacttaaa
      241 ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc agtgaattta
      301 taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt tagacggtac
      361 tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga aacatttacc
      421 ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta ataatattct
      481 caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg gatttgatgg
      541 agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa ttgattctgt
      601 cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat ctcagaatta
      661 taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta tcaaagagct
      721 aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata atattgagga
      781 aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc ctaatcgtca
      841 attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg ttactgaatc
      901 ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg tgtttgatcg
      961 tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag atagtttaaa
     1021 tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata gtcatcaaga
     1081 aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag tatctcaagc
     1141 atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata gaattctaaa
     1201 tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt caaacgaagc
     1261 gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt tttttcgaat
     1321 aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac gaacaaattt
     1381 tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa aggaggaaat
     1441 ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca tttgaaggac
     1501 tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg accgttttat
     1561 caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt gcaggagata
     1621 attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa cagatgaaac
     1681 ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat ttctatcaaa
     1741 aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc gaaacggtag
     1801 agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga tttagttatc
     1861 gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa ctcacagatt
     1921 accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac tatgctcctt
     1981 tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg catatccatg
     2041 tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct caaggtcata
     2101 ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa ggaagttgcc
     2161 aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata tcattgagga
     2221 aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca aaagtagagg
     2281 atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat acagatgttt
     2341 tggaacggat acaatcagga gagctattag actatttgtt agaggaattc tcagatagga
     2401 taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat acgaagaccc
     2461 cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag acacctcaag
     2521 atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga atattgagcg
     2581 aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt aatcaagatt
     2641 ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg cttttggaaa
     2701 atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg ggggaaacga
     2761 agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt tcccttcaaa
     2821 aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg gcaaaatatg
     2881 gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc aaaatcgcgg
     2941 aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag aaaaactgat
     3001 cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag agcagttgat
     3061 ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt taggcatcac
     3121 gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac aacaattatt
     3181 caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga aagagctgca
     3241 agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga tccaacaaga
     3301 acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg cgaacaaaca
     3361 attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat ggcaatctct
     3421 caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc tggagtcttt
     3481 ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa cactggaaaa
     3541 gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc aggagcagga
     3601 actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag aatggcaaag
     3661 attacaaatt gagactagag aaacaaattc agaattgaag attttggaac aaaggtggca
     3721 ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga agcatcttct
     3781 ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc tccaaatagc
     3841 taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga cctatccagc
     3901 attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt atatgctgat
     3961 ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga aagtgatcct
     4021 tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac caaaaattaa
     4081 aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag gacaacttga
     4141 tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg gagaagaaaa
     4201 acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag gaaagatgga
     4261 tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga aattatatgg
     4321 cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac gacaaatcga
     4381 ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa tttcagaaaa
     4441 aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg ccagaagcta
     4501 tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac aaaaagtatg
     4561 gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt cggaagtacc
     4621 tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca atgaattatc
     4681 ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat ctgtaagact
     4741 gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag caagtgaaaa
     4801 tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat tggacgaact
     4861 ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg aatggggagc
     4921 acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg aaagacaatt
     4981 accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag gaaattatca
     5041 gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag aatttcccat
     5101 ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat ttgcttacct
     5161 ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct ggcttcatta
     5221 tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag aaaagtatca
     5281 aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga tgaaccaaat
     5341 cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta atcgatgagc
     5401 agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa aacggaaaaa
     5461 aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa tactgggatg
     5521 cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta aacggtaaaa
     5581 gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta acaagggtag
     5641 atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa gaagaaatgg
     5701 aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat cgtattgttc
     5761 gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca aaaagaaacc
     5821 atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac ttagggaaat
     5881 caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt atcattttgc
     5941 atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat acgcttgcag
     6001 gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc tgtcttgcgt
     6061 tgaaaatcag cgaagctgac gaagatgttc tcgtattacg tcatatggtt ttagcacacc
     6121 atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca gaaatattac
     6181 atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt cgtcaaacag
     6241 aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc tatgtaccaa
     6301 aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag acataagtct
     6361 tcgctttttt tgttttc
//
LOCUS       DADGKS010000123         6317 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.128, whole genome shotgun sequence.
ACCESSION   DADGKS010000123 DADGKS010000000
VERSION     DADGKS010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6317
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.128"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(169..3318)
                     /locus_tag="JXV47_002757"
     CDS             complement(169..3318)
                     /locus_tag="JXV47_002757"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="HAX1488753.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDSQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDGVYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNEKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKTLMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSSEQINRMIDQMEPVKKESYLDPAVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQLIREGRTM
                     EDPDFPRIAITYSLEENSRDSSAQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLAIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PDKTKGLIVTFRKPATMEKNVEDATKLYSKAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSPTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYLPGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(3331..4548)
                     /locus_tag="JXV47_002758"
     CDS             complement(3331..4548)
                     /locus_tag="JXV47_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HAX1488754.1"
                     /translation="MSNDTQPEIRFPGFTDDWEQRKLGDFVVDYVEKTSVQNQFPMLT
                     SSQQKGIVLQEDYFANRQVTTENNIGYFVLPRGYFTFRSRSDNDVFVFNRNDIIDRGI
                     ISYFYPVFTLKSADSDFFLRRINNGIQRQLSIQAEGTGQHVLSLKKFKNIVAMFPSEE
                     EQQKIGTFFKQLDDTIALHQRKLDLLKETKKGFLQKMFPENGAKVPEIRFPGFTEDWE
                     ERKLGELGKTQSGIGFPDAEQGGSEGTPFFKVSDMNNIGNEYEMRNANHYVSNEQIER
                     KKWKPIKDVPAIIFAKVGAAIMLNRKRLVTSPFLIDNNTMAYLFNNTWDIYFGKILFE
                     TINLPRYSQVGALPSYNSSDIENISVKVPVKDEQQKIGTFFKQLDDTIALHQRKLDLL
                     KETKKSFLQKMFV"
     gene            complement(4538..6133)
                     /locus_tag="JXV47_002759"
     CDS             complement(4538..6133)
                     /locus_tag="JXV47_002759"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HAX1488755.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAIAPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVDVLEHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLATFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKKLLEAIS
                     SLQTTPENEAWLQGALEVFKHEQ"
BASE COUNT         1756 a         1300 c         1044 g         2217 t
ORIGIN      
        1 acaacggggt ggggtaaatg aatgaaaaag gtggaggaaa cattattcaa tagctgtctt
       61 aaatacttcg ttataaaatg tgaacaaata aaagacatct atccctattt tctacacttc
      121 cacttgacta ccatctttga atcgtacaat tttcttaact cttctcgttt acctcaattc
      181 attctcaagt ggaatcaact catcatctaa cattttacgc catgctcgct tcatttcttg
      241 tgggtattta aatggcttcg cttctggatg tttggcttta tatccttcgt aatccttact
      301 gttgataatt gctttcatat taggaattgg atcttcacct ggtagatatt gcagattaga
      361 agcatgtaat tctttctcag aaacaaacca ctcattggaa aagacatgaa tcaaatcatc
      421 actcgcttgt gtaaaatagc gacgtttaat gacaaagata tcttcattac tatctaaagt
      481 ccccacatca aatgcattta aaatttgtcg gtaaacttct ttgactcctt ctgttttatt
      541 caatttagcc aaagcttttt caatttcttc tcgtgcatct gaactattcg cagcataagt
      601 tcctagtaat tgatcaatat aagttgaatc aatatcatac aacttagtgg tattttcact
      661 ataaaattcg atcgttgaaa aatcttctcc ttctttttct ggttcttcct ctattaatga
      721 acccttcacg gtctcgtaca cgccaatttg ttcttccaaa agttgaattt gattgttcaa
      781 agttggagat ttcaccatgt catcattgta atcgtcataa gtcactaacg attcataagc
      841 acgattcaat tcttgaaatg ctttgacgta ctcgatacgg atttcaagtg gcgtatgttc
      901 atcaatggat tccatggatg aaacctcttt taacttacca tatgcttgtt tgaatctttt
      961 tttggattcc tgataacttg gataaatcaa acctgattct tcttttgctt ttgaatacag
     1021 ttttgtcgca tcctcgacat tcttctccat tgtcgctggc ttacgaaacg tcacaatcaa
     1081 tccttttgtc ttatcaggat acgtacgatt cgtacgtgaa aaagcttgga tcaatcctgc
     1141 atactctaga ttacgatcca caaatagggt ttgaatcgta ggggcgtcaa aacctgttaa
     1201 tagacgatcc actacaatcg ctaaatcgat ttgtttccca aattgtttga attccgctct
     1261 ttttcgtgcc aaacgattat tgatgtctcc gttataacgc tcaatgtctg ctaatgacca
     1321 ggaagtatca taatactgat tatattcctc aataattttt tgcatttctt cttgttgggc
     1381 acttgaatct cggctatttt cttctaatga ataggtaata gcgattcgtg gaaaatcagg
     1441 atcctccatc gttcgtcctt cacgaatgag ctgattggga aactcttttg ttaaccaatc
     1501 aggctctttc gtcatctctt tgatggcccg ataatacttt ttggccatgt caatggaact
     1561 cgtggttaag attgcagatt tcgttggcct gccatttcga aaatcaaatt ttgtataggc
     1621 attatctgga cggaacattt tatgaatgac tttttggata tgttcatctg cttcaaaaac
     1681 agctgggtcc aaataacttt cttttttgac aggttccatt tgatcaatca tacgattgat
     1741 ctgttctgat gaatactctg catatgtttc tacttctttt aatttccgat agattttatt
     1801 ctctagtgaa gtcggctcca cggtgttttc atgctctact tgaaatccta agacagagcc
     1861 atcttctagc gcattcttaa tggtataggt atgcaagacc tctccatact gatcatgggt
     1921 tgtacgtgcc aattgccctt tggcttgttt ccgattctca ggaaaaatcg gtgtacctgt
     1981 aaagccaaac caagtggatt tcggaaacat ttttttgatt tcttccatat tttcagcact
     2041 taacgctcga tgacactcat ctactacaaa cacgatatgt tggcccatta atttttggaa
     2101 gcgattggtt ccttttttct cttcttgttt ctttgcatat ttcaacgccg catctagttt
     2161 ttgacgggtt gtaatgatta caacatttgc attggcatct gccaacaggg tttcacttaa
     2221 ttctttggca cttcccgttc caacgatcaa gctattcgct ttggcgttcc cggaagaaat
     2281 cccagtatta aattccgaag caaattttgt aaactctgtg gtggtttgat tatctaaatc
     2341 tttgcggtcc actaacatga tcgttcgatc gatccccgat tttcgtgcta aaagcttagt
     2401 agatacaaaa ctagtcaacg tctttcctga accagtcgca tgccacacat accctgattg
     2461 atgtttattt gcggcaataa acaaggcttg aatcgcatgt acttgataag gatgtaacac
     2521 catgagggtt ttattgtctt gatcttcact gacgattgta taatccgcaa tcaaacgatg
     2581 agcatccggg atatttaaca cttgtttaca aaactcatat aagttttcta ctttttcatt
     2641 gtctttcgtt cgccaactaa ataaaaactt agggtgcaag tctttcggta aggcatttgc
     2701 aaaataccga gtggtttgtt cattggaaac cacaaacaac tgtaaggtcg aaaagatatt
     2761 gttccgaaac ataccttctt ctgcatattt tttgatttgg ttaaatgcct gataaacacc
     2821 atcttttgca gttacttgtt tcagctcgat ttggacaatc ggtaatccat tgattaataa
     2881 ggtgacgtca aaacgtcgat cccgtgcttc tatgttactt ccacgttttg caatttgatg
     2941 gaccacttca taagtagaga ttcctccacc aatgtcttga ttggaataaa ggataagtga
     3001 gacagaaccc aattgcgaat cttcccgttc aatcgtgatc cgagccatcc cattttcacc
     3061 ttttaaccat ttcgcagcat caaatggggt tttcgttcgc agcagtaatt ccgttttgat
     3121 cgtttcaaat tctttatcgg tcaaaggaaa atcattcagt tctgcttgat tatttgagat
     3181 aattttttgg cgtaaattga cccaaaggtc ttcttctgat tttagatccg gacgatacgt
     3241 ccactgatta tgcccttctc caagtacacg aatcaactgt tcttcgactt ctgcttcctc
     3301 acggtgacta attttcattc ttcttccctc ctagacaaac atcttttgta agaagctttt
     3361 tttcgtttct tttagtaaat ctaacttacg ttgatgaaga gcgatcgtat catctagctg
     3421 tttgaagaaa gtaccgattt tttgttgttc atcctttaca ggaaccttaa cactgatatt
     3481 ctcaatatca gaactgttat aagaaggcaa tgcccctact tgggagtatc ttggcaaatt
     3541 tatagtttca aacaatattt taccaaaata gatatcccaa gtattattaa ataaataagc
     3601 catggtattg ttatctatta agaaagggct tgtgaccaaa cgttttctat taagcattat
     3661 tgctgcgcca actttagcaa atataatcgc tggcacatct tttattggct tccatttttt
     3721 acgctcaatt tgctcattag atacataatg atttgcattt ctcatttcat actcattacc
     3781 aatgttattc atgtcggaaa ctttaaaaaa tggagtacct tcagaaccac cttgctcggc
     3841 atcaggaaat ccaattcccg attgagtttt acctaattct cccaacttac gctcttccca
     3901 atcttccgta aaaccaggaa accggatttc tggcactttt gctccgtttt cagggaacat
     3961 tttttgtaag aatccttttt tcgtttcctt cagcaaatct aacttacgct gatgaagagc
     4021 gatcgtgtcg tcaagttgtt tgaagaaggt gccgattttt tgttgttctt cctcactagg
     4081 aaacattgct actatatttt taaacttttt tagagacaga acatgttgac ctgttccctc
     4141 tgcttgaata gataattgtc gttggattcc attgttaata cgtcttaaga agaagtcgga
     4201 atcagcagat tttaaagtaa atacaggata aaaatagctt ataatccctc tatcaataat
     4261 gtcattacgg ttaaacacaa acacatcatt atcacttcga ctacggaacg tgaaatatcc
     4321 tctaggtagt acaaagtaac caatattatt ttctgtagtt acttgccgat ttgcaaaata
     4381 gtcttcttgc aaaactatcc ctttttgttg agatgaagtt agcataggaa attgattttg
     4441 tacacttgtc ttttcaacat aatctacaac gaagtccccc aacttcctct gttcccaatc
     4501 atctgtaaat cctgggaaac ggatttctgg ttgtgtatca ttgctcatgt ttgaacacct
     4561 ccagcgcacc ttgtaaccac gcttcatttt caggtgttgt ttgcagggaa gagatagctt
     4621 ctaaaagttt tttttctagc acttgctgtt cttgtcgtat cttcttgatg tcatttccga
     4681 catgaaccat atcaattggt tcttcttctt cgaaagtatc tacatagcgt gggatattta
     4741 agttatagtc attttctttg atttcatcaa aggttgccaa atgagcgtat ttctcgacat
     4801 cttttctttc agcgtaggtt tcgaggattt tttgaatgtt ttcttccgat agtttatttt
     4861 gatttttccc tttaacaaat tcacgactag catcaatgaa taatacatct cgagtttgac
     4921 gattcttctt caacacaatc accgtcgttg gaatcgatgt cccaaagaac aagttcgcag
     4981 gcataccgat cacagcataa atactgccat cttctagtaa tttttgacgg atgacccctt
     5041 ctgcagcgcc acggaataaa actccgtgtg gtaagacgat ggccatggta cctgtttcct
     5101 tcaaatgata gaacccatga agaagaaacg caaaatctgc tttggatttt ggcgctaatt
     5161 tcccataacg attaaaccga gaatcatcta agaaagtcgt atctgctgac caattagccg
     5221 aataaggtgg gttcattact actgcatcaa atgtgtaagg ttcatctgtt ggccagtcct
     5281 tattcaacgt atccccattg cggagattca tttcttcggc gtcgacacca tgtaaaatca
     5341 agttcatttt tgctagattg tatgtcgttg tatttagttc ttgcccatga tatttaacgt
     5401 tatctgggtg tgttaagtag ttacgtacgt ttaacatcaa tgaacctgaa cccatcgttg
     5461 gatcaaaaac actaaagaat cgtcgttcct tttgatcgag cgttacgatt tgcgccatca
     5521 tatcagaaac catatgaggt gtgtaaaatt ctccggcttt cttccctgct tctgaagcaa
     5581 attgactgat cagaaactca tacgcatccc cgatcacgtc cccatcgtgt tctaaaacat
     5641 ctacatcatt caatttcttg atgacttcgg taatcgtcac atttcgttgt tgctcatctg
     5701 ttcctagttt ttttgattgg agatccacat catcaaataa cccattaaat tgattgtagg
     5761 tagatgccaa ttgcacaaag gctttgttta gatcgttcaa ttggaacgtt gcttgttttg
     5821 cttgatccgc taagacgttg aaaagatact ctggtgcaat tgcatatccc aaaatatcaa
     5881 cgattgtggc aatcagatct tcttttgatt cttcatctga aagtaattca cgatacaaca
     5941 ttgtttgttt gcttactgtg tcatattcct ctaaggattc atctgctaaa agaaccactt
     6001 gttccaacaa tcgatcggat aaatatttat agaaaatcag tcccaataaa taatttttat
     6061 attctgacgc atccatttta ctacggagat tatctgccgc actaaataat ttttgattta
     6121 attctgcacc caaaaagata cactcctatc tcttatttaa agttgctata taccctctta
     6181 ttttagcata ccccctttta taaaaagcaa aaaaaaaaag aaagaaactt attcttgcta
     6241 ataaactacg cgaaaggagt ctaacgttgt ttgatataac ttagactgat cgttaactta
     6301 ttttttatat ttctaca
//
LOCUS       DADGKS010000124         6230 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.129, whole genome shotgun sequence.
ACCESSION   DADGKS010000124 DADGKS010000000
VERSION     DADGKS010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6230
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.129"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            133..633
                     /locus_tag="JXV47_002760"
     CDS             133..633
                     /locus_tag="JXV47_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAX1488756.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            730..2577
                     /locus_tag="JXV47_002761"
     CDS             730..2577
                     /locus_tag="JXV47_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HAX1488757.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            2580..3476
                     /locus_tag="JXV47_002762"
     CDS             2580..3476
                     /locus_tag="JXV47_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAX1488758.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNLYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            3526..3915
                     /locus_tag="JXV47_002763"
     CDS             3526..3915
                     /locus_tag="JXV47_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAX1488759.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            3902..>6230
                     /locus_tag="JXV47_002764"
     CDS             3902..>6230
                     /locus_tag="JXV47_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAX1488760.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTDALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT         2106 a          925 c         1336 g         1863 t
ORIGIN      
        1 gagttttcca aactgattgg cttcttggtg attgctttga ttgcggtagg tctggtcttt
       61 aatgcttctg gtgtgaagga tgtcttactc aatttgttta accgaattgt cggtgcctga
      121 gggggaatca caatggaaca gatacgtgtt tatattgcga accttggaaa atacaatgaa
      181 ggtgagttgg tgggggcatg gtttacccca cccgtcgatt ttgatgaagt gaaagaacgg
      241 attggattaa atgacgaata tgaagagtac gcaattcatg attatgaact gccttttgag
      301 attgatgagt atacaccaat tgaggaaatt aatcggttgt gtggtttagc ggaagagctt
      361 aaaggaacgc caattggtga ggtcgcttca gagattcaac atgccttctt caattctttc
      421 gaggaaatgg tagagcatgt ggatgatatc atctattatc ccgattgtaa tgacatgagt
      481 gatgtagcgt attacttgat tgtagaagct ggtgatttag gcgaagtacc agaacacttg
      541 aagacgtata ttgattttga tgcgtgtggt cgagacttgg agattggcgg gaattatttg
      601 gttacgagtc gaggggtttt tgaactaatg taaatcattt gttagaattg accagaaatt
      661 tctatcgtac ttttactttt ctatttgata tactgaaata gaaaatattt gttgataggg
      721 gtgttactaa tggttggcaa taagtggtac aaatgtgatc ttcatattca ttcaactgcg
      781 agtcagtgct ttcaggataa aaaggttact gctaaggaat gggtagaaga atgtttaaac
      841 aaaggactcg attgtgttgc attaactgat cacaatacag gggaaaatat tgatgaatat
      901 aagaaagtgg ctatcgaaaa tggcttagat ttttttcctg gagtggaatt aacgtgtgga
      961 gaaaatggaa ctcatttact agtcctattt gataaaagtg catgtacaaa tgatatctct
     1021 gatttcttaa ccaagatggg tataaaaaga gaggattggg ccagcgctgc agcttgctca
     1081 atgaaatcag ttttagaagt tattgatttt gctgagcacg agggcttgct cgttattcct
     1141 gcacatatag atgagtttaa tggaatttct tcagcaaaat ttggaaatct aggaaagata
     1201 tttgaatcag aaaatatata tgcagtacag acggttcaaa aagaattttt tgaaaatcgc
     1261 tcacaaatga ttccctcatc taagcgtgac actatctatg atagtgtgaa tgccagatat
     1321 gatggtagag ttggaaaaga tactttggaa tcttggtata aatcagttgt tgaggcagaa
     1381 aaaaataata tgacatttct tagcttttct gataacccac actcgaaagg aaattcaaaa
     1441 catggacttt ggggaatagg cacaagatat tcctatataa aaatgaagga cgaacctgac
     1501 ttgggatcac ttcgcgatgc tttaatgcta ggcgaaactc gagttcattc tgatttttct
     1561 aatttctcca ttaatgaaaa tgaagtttta ttggaaaaat taagcttttc tgggaccact
     1621 cttagcacaa aagaagttgt agtcgaattc agcgataatt taacttcaat tattggagga
     1681 agaggaacag gcaaatcttg tattacaaga ttcttggtct atgtccttgg aaaggaagca
     1741 gaacttgatc aattttctga aatacaaagt gattatcaga actttgcaca aattgaacat
     1801 aatggctctg gaatattttt gaaggataca attgtgaaac tgaatatttt ctataagggg
     1861 acaaaatatc aaataataag aacacaggat agacattcta tttatgaatt tacacaagag
     1921 aatggtctgg ttgaaaaaga aacagaacgg ttgagaatga tttccgataa ggtgagtata
     1981 tactctcaaa aacaaattta tgaaatttca aaaaatcaaa ctagtatact agaattacta
     2041 gatggatata actctgattt gatttcagag tataaaaatg agattgaaac atgtgtaaac
     2101 gaaataagaa aattaaattg ggatattgtt tctgtgaaaa aagaaataca agataaggcg
     2161 aaggtagagc ttgaaattga agatttaaaa aaacaagtag aaaagctatc tcataagagt
     2221 tataaagatg tttatgatga gtattcaaaa gagacagata tttataggga actgaaacgt
     2281 gatgtggagg cacttaagga aattcccaaa aatctaactg atagtgttga caaaattgac
     2341 tttggcaatg gtataaaagt tacagacgaa attgatgaac accgcggaga attgattaag
     2401 aatttagtga ccaatcgggc taagattcaa acaataatta atgaaatgtc agatgaaatt
     2461 gatagttata gagcagagct gaataaatca gattggaaag ttaactataa tgaggtttca
     2521 aagaggtatc aaagaggtat caaaaactta gtgaagagtt atctcaagat gaattaaaaa
     2581 tgttacaaaa ccttgattct ttatatcaat ctttatcaaa aactgaagag cgattggaag
     2641 aaattattca acaagaaata aagcttaaag attaccaagt tgaggttgac tcagcaatgt
     2701 caagaatgaa taaatcatat caaaatctct attctgagag aagtagttcc tcgcgcgaaa
     2761 ttttttctga tattacagga atagaggcta ctattcaacc aaatagggat ttcaataatt
     2821 atgttaaaga gctcagagct tgtattaata aggaggacac ttttgacagt gagtttggat
     2881 ctcttattga taagctgaca aaaaattcca ttactaatca agatatatat aatgacatac
     2941 ttgatataag agttagtggg gaaagtagta ttttttcaga taaaaaatta atcaattcta
     3001 taagaaaatt gaatgatgca caagttcttg aattacaaac ccttaagcca aatgatttag
     3061 tagttatccg acttgaacta aatggaaaaa aagttagttt atcgaatgct agtgctggtc
     3121 aaaagacatc tgcaattctt tctatgattt tggcgtatgg aaattcacca ctcatattgg
     3181 atcagcctga agatgatttg gatagtcaat taattaataa cttaatcgta agaagtatca
     3241 ttacaaaaaa ggaaaacaga caaattttaa ttgtaactca taatgcaaat atcccagtta
     3301 atggtgattc agaatggttg attagcatgg gagattcaaa agaaatatcg gctgatcagt
     3361 gcgggtcggt agatgaaccc aatatcaagc caagaatatg tactgtgatg gaaggtggcg
     3421 aggatgcttt tacaaataga gcgaaacgct atggttttaa acaaattgta gaataacact
     3481 agagggtgag acatattatt atgtccgccc tttttaggag gaaaaatgaa aaaaataaaa
     3541 agctatacca gtatctgggc agttgaaaaa gtcatttacg caatcaatga ttttcagttg
     3601 ccttttcctg tgacttttaa ccaaatggct tggttcgttt tatctttact gtttgtcatc
     3661 gtatttgccc atgtgcctcc actatctatg atagaggagg tctttttaaa atacttaggc
     3721 ataccggtgg ctgtcacttg gtttatgtcg caaaagacgt ttgatggcaa gaaaccactg
     3781 ggatttttac gatcctttat cagctatcac ttgcgattta aggtgacttt tgcaggaaag
     3841 aaagtcaaag aacagaagaa acgatgggat gaacccagta ctcttgtaag gagtgtgaac
     3901 tatgtatccg attaagtata ttgaaaataa tctcgtcttt aaccaagaag gcgagtgttt
     3961 tgcctactat gaattagtgc cttacaatta ctcctttttg tcacccgaac agaaatttca
     4021 agtgcatgat aactttcgcc aactaattgc gcaaaatcgt gaaggcaaga tccatgcgtt
     4081 acaaattgcc acagaaagta gtattcgcgc cacacaagaa cgatcaaaaa aagaaattac
     4141 cggtagactc aaagaagtag cgaaacaacg aattgatata cagacagatg cattagtatc
     4201 catgattggc gatagtcaga ttgattatcg cttttttatt ggctttaaac taattgcgac
     4261 agatgaagaa gtcaatctaa agagtctcaa gaaatctttc ttttctgggc ttcaagaatt
     4321 tgtctatgga gtgaatcatc atttgatggg cgattttgtt tccttatcca atgaagaaat
     4381 tcgctgctat tctaagcttg aaaaattaat ggaaagcaaa ttggctcgaa gatttaaagt
     4441 caggcgagtc acaccgagtg acctgacgta tttgattgaa catatttatg gcgaaaaagg
     4501 gataccgttt gaagaatacg aatttcagct accaaagaaa aagctaaaat cagaaacact
     4561 ggtgaaacgt tatgacttat tacgtccaaa tcgttgttta attgaagaaa aaccaaggtg
     4621 cttacggatg gaacatgaga atcatgagtc gtacgtagcg tatttaacaa ttaatacaat
     4681 tgtgggggag atggaatttc cttcctcaga acttttctat taccagcaac aacaatttac
     4741 attcccaatc gacacaagta tgaatgtaga gattgtgacg aataaaaagg ctttagctac
     4801 cgttcgtaat aagaaaaaag aactgaaaga tttagacaat catgcttacc aatctgacaa
     4861 tgaaacgaat tccaatgtct tagatgcttt ggattccgtg gatgaattgg aaaccacctt
     4921 ggatcagtca aaagaatcta tgtacaaact gagttatgtg gttcgagtga gtgccgaatc
     4981 agtggatgaa ctaaagcgac gctgtgatga agtgctcgat ttttatgatg ataccaatgt
     5041 aaaactagtc cggccctttg gcgatatgat ggggctacat gaagaattct taccctcaag
     5101 taaacgatat atgaacgact atattcagta tgttacgtct gattttttgg cggggcttgg
     5161 ttttggggct actcagatgc taggagaatt agaagggatt tactttggct acaatgtgga
     5221 tacaggtcgt aatgtttacc tgaaaccggc attggcttca caaggagtca agggttcagt
     5281 aaccaatgcg ctggccgccg ctttcctggg ttctcttggt ggaggtaaat cctttagtaa
     5341 caatctctta gtctactatg ctgttttgtt cggtggtcaa gctgtgattg tcgatccaaa
     5401 aggggagcga ggagggtgga aagaaacctt gccagaaatt gcggatgaaa tcagtatcct
     5461 caacttgacg agtaagtcag aaaatcaagg tctgcttgat ccttatgtga ttatgaagaa
     5521 aaagaaagac tcggaaagtt tagcaattga tattctgact tttttaacag gaatttcaag
     5581 tcgagacggg gagaagtttc ctgtgttacg taaagccatt cgaacggtga ctcaaagtga
     5641 tcaacggggg ttattacaag ttattaacga attgcgaaaa gacgggtcac caatcgcgga
     5701 aaatatcgcc gatcatatcg agtcctttac cgattatgat tttgctcatt tgcttttctc
     5761 agacggctcg attacccaat cgattagttt agataaacag ctaaatatca ttcaagtggc
     5821 ggatttggtt ttaccggatg cagaaacgac ttttgaagaa tataccacca tggaattgct
     5881 tagtgtttcg atgctaatcg tcatttccac ttttgccttg gactttatcc atagtaaccg
     5941 agaaatcttc aaaattgtcg atttggatga ggcttggagt tttcttcaag tggctcaagg
     6001 aaaaacgtta tcgaataagc ttgttcgtgc tggtcgggcc atgaatgctg gggtctattt
     6061 cgtcactcaa aatagcgacg atttattaga tgaacgttta aaaaataata tcgggttgaa
     6121 gtttgctttt cgcagtaccg atattcatga aatcaagaaa accttggaat tctttggttt
     6181 ggatcaggag gatcaaagca atcaaaaacg cctgcgagat ttggaaaacg
//
LOCUS       DADGKS010000125         6154 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.130, whole genome shotgun sequence.
ACCESSION   DADGKS010000125 DADGKS010000000
VERSION     DADGKS010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6154
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.130"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(137..1099)
                     /locus_tag="JXV47_002765"
     CDS             complement(137..1099)
                     /locus_tag="JXV47_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAX1488761.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1101..2540)
                     /locus_tag="JXV47_002766"
     CDS             complement(1101..2540)
                     /locus_tag="JXV47_002766"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HAX1488762.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2725..4671
                     /locus_tag="JXV47_002767"
     CDS             2725..4671
                     /locus_tag="JXV47_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HAX1488763.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            4935..5807
                     /locus_tag="JXV47_002768"
     CDS             4935..5807
                     /locus_tag="JXV47_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAX1488764.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT         1958 a         1051 c         1093 g         2052 t
ORIGIN      
        1 atttctccac tccaaaaaag tctaactttt gggggtcact acaagttgac aactcctttt
       61 tgtttacaaa tcaattggat atctacaaat tgtattttct aacgaatttt atagacatta
      121 aaaaattaat ttaacgttaa atacttcctc cagaaagtat tgagattggt aaaatataat
      181 ccttatttgt cttttcgcct ttaatttttt tcagaagaat atcaacaata agacttgcaa
      241 tttcatcaat tggttgtctt attgttgtca attgtgggaa aaatttctca atgaaagagg
      301 taccatcgta tccaataatt tttaaatctt ctgggatatt aagtttaagt tgatgagcaa
      361 ttttcatagt gagaatggct gttaaatcat cagaaacaaa aataccatct ggtttgtgat
      421 ttataatagt tgactttatt tccatttcac gacggatagt agacagatta ttaggaattt
      481 tgaaaatttt tccatttgga ttttgaaaag aaaaacctag tgcacgtaat tctgtgggag
      541 aatccgtgtt atcatttcct gtaatcataa tggtattttg acaaccattt ttttgtaaag
      601 tcttagctgc aagttttccc ccttcaaagt tatctgaaga aacaatggaa acattaggag
      661 ctaaatttct atcaaaagca acaataggtg ctctcacacg ctcataatca gcaattccaa
      721 gattatggct tgatgagatt atgccatcaa cttggttggc ttcaagcatt tcaatgtatt
      781 ctctctcttt agcaggatca ttttgactat tgcaaataat cgttttatat ccatgtttaa
      841 ataactctat ttcgagatac tcaatgagtt cagagtaaaa gatattacta atattaggaa
      901 aaataagacc aataagctga ggtgactttc cttgaagtcc acgtgctaaa ttatttggtt
      961 tataaccaag agttttcata gcttcatgaa ctttttgttt tgttttttct gataaatatc
     1021 ccttattatt aatgacgcgt gaaacggttg ttgggctaac tccagctaat tcagcgacat
     1081 cagttaattt tgctaccatt ttaatatttt aattcaaagt attttccagt aggttcgcct
     1141 gatttgattt gaataccatt ttggtgattt tcagggaata cacgactagt aaacactttt
     1201 tctcctttat taataaaaat ctcaatgatt gagttatcta caaaaatgtt agcagttgtt
     1261 tctttagtat caattgagca ttcacgaatc gtaccaaagt cagtggcata ttgaatgcct
     1321 gctttgctgc gatctaaaat aatttttcct tctttggtat ctacaatcaa gctaagtcca
     1381 tttcctttac tatcagagaa aagaagtaac tccgatttct gatttggagg aaaagttagt
     1441 tcaagctcat aagtattatt tgtttctgct tttgctgtaa attgttcaga actagcacgt
     1501 aatgatgtaa tagcttctac tggatattgg taaagtttac catcttttat tgaaagttct
     1561 tttacaagac tcattgctcc ctgataatca tacttatcag ttggataatc gatatcaggt
     1621 agtccaatcc aactgacaat cagagcacga ccatcaggag tattgaatcc ttgagtcgca
     1681 tacgcttcaa atccataatc aagattttga atttctgaag cgcccacaag ttttactttt
     1741 tctatgtcaa gcgattgaca gatcttaaaa gtattcggat agatattccc ataatttagc
     1801 tcagatttat ccaacccttg aggacaataa atgagaacag gttttttgtc tacaaatact
     1861 agatttggac actcaatcat gtattctgaa ccagtgccgc caaaatcaag gttgccaact
     1921 tcctcccatg tttccacgtt attgtcatcc gctttgtaaa gtttgataaa gcctgatttt
     1981 tctaaatttt gtgctccaac aatcgcatac aattgtcctt cataattaaa catttgtgga
     2041 tcacgaaaat gatcagttac atcagcaggt ttatgaataa gaacattctc acctttcgta
     2101 atgttgtagt ctttatccat ccatgctccg atttgaagtg tatcacgttc ccaattttca
     2161 tttcgaacgt ttcctgtata gagtaagaat agattcccct ctatttcata tgcagaaccg
     2221 gaataagcgc cgtggctatc tcgttttgtg tctggaagaa gttctgctcc tgttacatga
     2281 aaatgaacta aatcatctga ttcattgtgt acccattctt tcaacccatg agcagctcca
     2341 aatggccaat tttgataaaa aagcgtatat tttccgttaa aaaaagaaaa accattagga
     2401 tcgtttaaca atcctgtttt aggttcgata tgatagctag cacgccaagg tgatcgtttt
     2461 acattatcct taattttatc catctcatct ttagtccaat cagaataagc acgatatcgt
     2521 atttctcgag gtaagttcat attttactcc ttcaatttat ctttttacaa ctagtatggt
     2581 aaacgttttc cgttgaaaaa tcaatcattt catttaaaaa aataaactat atgacaaacg
     2641 tttgacatat ttttaagata tgctaaaata aatttgcatt tcagtgaacc gttttcacgt
     2701 aaaaataaaa aaggagtgat tcgaatgaat tacagtaaag tagcttccga cgtaatacaa
     2761 gcggtcggaa aagataacct tattgcagct gcacactgcg ctacacgtct tcgtctcgta
     2821 ctaaaagatg acacgaaagt gaatcaaaaa gctttagacg aaaatccaga tgtgaaaagc
     2881 acatttaaaa ttgatggaca atatcaagtg attatcggtg caggtgatgt taatttcgtt
     2941 tatgacgaac ttatcaaaaa aactggactt tcggaaattt caacagatga tttaaaacaa
     3001 attgctagta aagataaaaa attcaacccc attatggcat taattaaatt attatcagat
     3061 atttttgttc caattatacc tgcccttgtt gcaggtggtt tattaatggc attacaaaac
     3121 tttttaacag ctgctggact ttttggacca aaatcaattg aagaaatgta tcctgcgatt
     3181 gaaggtattt cctcaatgat ccaactgatg tccgctgcac cattcatgtt cttaccaatt
     3241 ttagtaggta tttcagctgc taaacgtttt ggagcaaacc aatttcttgg tgctgcaatt
     3301 ggtatgatca tgacaacacc agatcttggt ggctcaactg aatattggaa tatttttggt
     3361 tatcatgttt cacaaacaaa ctatgcttat caagttattc cagttttagc agctgtttgg
     3421 atattatcta tattagaaaa attctttcat aaaaaattgc catcatctat tgactttaca
     3481 ttcacgccat tattatcagt aatgattact ggatttttga ctttcacagt tattggccct
     3541 gtaatgttat tgttgtctaa tggaattaca gacattattg tttggctata taacactact
     3601 ggatttattg gaatgggtat ttttggagga acatattcac ttatagtcat gactggttta
     3661 catcaatcat ttccagctat tgaaactcaa ttactttcag cgtggacaaa tggtatcgga
     3721 catggagact ttatctttgt agttgcatct atggcaaacg ttgctcaagg tgctgcaaca
     3781 tttgccattt ggttcttaac taaaaattct aagacaaaaa gtcttgcttc ctctgcgggt
     3841 gtctcagcac ttcttggaat tacagagcct gccttgttcg gagttaactt aaaataccgc
     3901 tttccattct tttgtgcttt aattggttca ggaattgcta cagcagtagc aggattactt
     3961 aaagtagttg ctgtttcact tggttcagca ggtttcttgg gatttctttc aattaatgca
     4021 acatctattc cattttacgt attgtgtgaa ttgattagct ttgtagttgc ttttgcaatt
     4081 acttacttct acggtaaaac aaaagctgct ggtatcttta aagcagaaga aattgctgaa
     4141 caaacaccag ttaattcttc aaaagtagca acaacagatc caatatctac tgatgttgaa
     4201 tcaacacaaa caaaagtttc atcagaaaca attgttagtc ccatttctgg taaagtgatt
     4261 agtctttctt cagtaaatga tccagtcttt tcatcagaag ctatgggaaa agggattgcc
     4321 attaaaccaa atggaaacac ggtccattct ccagtagatg gtactattca actcacgttt
     4381 gaaactggac atgcttatgg tattaaatca aataatggtg ctgaagttct aattcatatt
     4441 ggtattgata ctgtatcaat gggaggaaaa ggatttacac aaaaagttac tactaatcaa
     4501 aaagttagaa aaggcgatat tcttggagca tttgaccgtt caatgattga gaaagaaggt
     4561 cttgatgata caacaatgat tattgtgacc aatacttcgg attattcaga agtaaatata
     4621 gtagctgaaa atacagtcac tgagggtact gatttacttg aaatcaaata aatatatttc
     4681 cctgagtaaa gatggaattt tctttccaaa atcaaataat atagattaat caaatatttg
     4741 agaataacat tttatttaat cttttcatat atcaattgta tgaaaaatta ttagaatttt
     4801 aaaaaatgat aaaaattcaa aaagaaaaaa tagtagttat ttacttgtca tgttactaaa
     4861 taaaaaaata atttaaatat gatatatagt catttattta gtgatttcat tctaaaataa
     4921 agggagaaat gtctatgcta tacggtgcaa ttgaagcagg cggcacaaaa tttgtgtgtg
     4981 ccattggcga tgaagaaatg acgatcaagg aaagagtgag ctttccgaca acgacacctg
     5041 aggaaacaat gcctttagtc attgacttct tcaaacaata ccaagcagat ttagcaggga
     5101 ttgggattgg ctcatttggg cctatcgata tccatcgcga ttccgccact tatgggtaca
     5161 ttacctcgac cccgaaattg gcatggcaaa attttgattt catcggtacc atgaaaaaag
     5221 aatttccgat cccgatttct tggacaacag atgtcaatgc ggctgcctat ggtgagtatg
     5281 tcttcggcag tggcaaagga ttgagcagtg tcgtttacta tacgatcggt acgggtgttg
     5341 gcggcggtgc cttacaagaa gggcgcttta tcgaagggtt tagtcatcca gaaatggggc
     5401 atatgctcgt cgtccctcat ccaaaagatg actttgctgg cagctgtcca tttcatggca
     5461 actgtttaga agggatggcc gctggacccg ccatcgaaaa ccgcttaggg aaaaaaggac
     5521 aagaggttgc agaagatgat ccttattggg aaatcgaagc ctcctatatt gctcaatgtg
     5581 cctacaatac aaccttgatg ttttctccag atgtgatcat ttttggcggt ggtgtgatga
     5641 aacaacgcca tatgctgcaa aacgtccacg acgcatttgc aaaattggtc aatgggtatg
     5701 tcgaaacacc tgagttaagc aaatatatcg tgaccccagc attagaagac aacgctggaa
     5761 cgctcggttg tttggcattg gctcgagaag cggtcttaca ttcataaacg aaaaaaggct
     5821 cttcgacatt tagtgttggt agagaaagat acaactgaaa atttagtcat aaccagttag
     5881 gcagagtgct taactggttt ttgttttact tggaagatca agccttgaat gagataaatt
     5941 cttgctcgaa agttatggaa atttcgatag ccgtaggcca cttgtattgt gcaatagttt
     6001 tttacaaaaa aaagggggtg cggatatttt tttggacctt tttaacaaat aggttctgtt
     6061 gcaaagtttt aaatctacta tcagataagg tagaataata gaaaaagata gcaggaggaa
     6121 tgacgatgag tcattttaaa ggaaagcaat ttca
//
LOCUS       DADGKS010000126         6065 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.131, whole genome shotgun sequence.
ACCESSION   DADGKS010000126 DADGKS010000000
VERSION     DADGKS010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6065
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.131"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            832..1566
                     /locus_tag="JXV47_002769"
     CDS             832..1566
                     /locus_tag="JXV47_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAX1488765.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1582..2751
                     /locus_tag="JXV47_002770"
     CDS             1582..2751
                     /locus_tag="JXV47_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAX1488766.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2767..3762
                     /gene="lacD"
                     /locus_tag="JXV47_002771"
     CDS             2767..3762
                     /gene="lacD"
                     /locus_tag="JXV47_002771"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAX1488767.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYEEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3841..4767
                     /locus_tag="JXV47_002772"
     CDS             3841..4767
                     /locus_tag="JXV47_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HAX1488768.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4786..6036
                     /locus_tag="JXV47_002773"
     CDS             4786..6036
                     /locus_tag="JXV47_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1488769.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         2026 a          997 c         1245 g         1797 t
ORIGIN      
        1 attggcgcag cgaatccttg ataatgagct cggatgtgct aacgctagcg aggcagtcta
       61 actttaactg ttagctcctg ccgaagatcg tcacatccga ggaggctcat tgtcaaggac
      121 aatcggaata gcatacggaa agaagttctg caccttataa aatttgtcaa aaaaactgtt
      181 gccattccaa agtttgaaaa atgctatttc gaggtagaag gatattatat aagcacggtt
      241 gactaaacga agtgataata aaaaaagtta ttcaagaata agaaaaatta tgatacgaat
      301 tcagataaac tggagaatac agagaccttt aaaagggata agaaacaaca taaattcctc
      361 ttaagagaga acgaaaggac aaagccagca acttgataca cgagctagta ttagaggaat
      421 ttattctcat agactccctt ttgaatacgt ttcaacttta attttcatgt tcataaatga
      481 tttgaaacca aagcaaatgc gttgcacttt tcctccgtct tccgaaaatc gttcaattca
      541 ctggtaagta gtcatttgat agtttgaggc aaattgttga ttgatgaagg gtaggagcta
      601 aaaaaagata ccagttgaag agagaaaaag aaaaaaatag agggtgttct tgaatgaaaa
      661 aagttggaaa attatttttc atttcctttt attcctatta aagtcagtga tgtcaatcat
      721 attaacaaga ctaaaaatga aaataaaaaa aagattgttc ttagtattga ctcataaaaa
      781 ataccactac tatacttaca ttgtggttat agccagttag gagagacatc gatgcaaaat
      841 acctttcaat caaaatcact ttattatcag ctggtagaaa tattgaaaca acgaatcgaa
      901 aacagtatgg tcgctcatga caagctgcca tcagaaagag agttgaccag tttttatggc
      961 gttagtcgca cgacggtgcg actagcattg caagaactgg aaaaaatggg ctacatttat
     1021 cgacaacatg gaaaaggaac ctttgtttcg gaattaagga caaatgcgac tgatctagct
     1081 ggcgcatata gttttaccga acaaatgcgg gcaatgggca aacatcctga aaccaagata
     1141 ttggccttca agaagattga agcaactaaa tatttagcga gtcatctgaa tgttcaacta
     1201 ggtgagcctt tatttcaatt agaccgattg cgcttagctg atgatttgcc aatgatgatc
     1261 gagaaatcct atttgccagt gaagctattt atgtcccttt ctcaagaaat tctatttctg
     1321 aaacctttat ataatttgtt ttcagagaat ttcaatcaaa tcgtacggtt ggctgacgag
     1381 gaattttatg ccagcattgt ccagaaagaa gatagtgagt tgctaaatat tccagaagga
     1441 tcaccagtgc tccatttagt tcgctcaacc tataatctcg agaacgaagt gattgaattt
     1501 acattaagtg tagcgcgggc tgataaattt cattataaga tcaggcatct gcgttccact
     1561 aactgaattg gaggaaagaa aatgtttatg ttctcaaaag aagaactacg aaagctagga
     1621 gcagaaaata ctacccgaga aattcgacaa caaccggaac tgtggcatga gacgtttgac
     1681 cgttatcaag aaacagttgc agatttagat cgtttgttta cggatgcgaa acaacatgct
     1741 ggagagcgac caatccgagt catttttaca ggggccggaa cctcgcaata tgtgggagat
     1801 acactaattc cgtttcttac tagtcaagga aatacgaacc agtttatttt tcaaagtatt
     1861 ggttcgaccg atatcgttgc tacgccaaaa gaatacctga ttcctgatga gacaacgatc
     1921 ttggtctcat ttgcccgtag tggaaatagt ccagaaagtc tagccgcagt taagatggcc
     1981 aatcagctgg tcaacaagat ctatcatatc gtgatcacct gtgcaccaga cggattattg
     2041 gctacacaaa tgcctacaaa aaaagaaaat ctagttttac taatgccaaa caaagccaat
     2101 gacgctggtt ttgctatgac aagcagtttc agctgtatga cgctgactgc gctacttatt
     2161 tttgatcaag caagcaatca gcaaaaagaa agatatgttc atcaattaag ccgactagga
     2221 gaagaagtca tccaacgaga atcagagatc caagggtatc tggcatcaga ctttcatcgc
     2281 atcatttact taggttcggg aagcttaggc ggattgacta gagaagcgca attaaaagtt
     2341 ctcgagttaa ctgctggaaa aatcgcaacc gtatttgata catctttagg attcagacat
     2401 ggtcccaaat cttttgtcaa tgagcaaaca ttggttttcc tgtttgtcag caatgactca
     2461 tatacgcaga aatacgatgt agacatgctg gaagaaatca aaaatgacgg tattgcccaa
     2521 cgcgttgttg gaattggtca aaagggttca ttgtttagtg gtgattcctt tgaattagtt
     2581 gcagattcgt tactgccgga tggctatctt gctttagcag atatcatggt agcccaaacg
     2641 atcgcattac tttgttcggt gaaggttggt aatacaccag atacaccatc gccaagtgga
     2701 acagtcaatc gtgtggtcaa aggcgtaacg atttatccat atgaaaaata ggaaagagtg
     2761 tgaagcatgt tagaatggtc ggaaaataaa agacaagcaa tggaacgtct atcgacgcca
     2821 gaaggcatta ttaccgcttt ggcgatcgat cagcgaggcg cgctgaagaa aatgatgtcg
     2881 gctttaggga tggaagcgac aaaggaaaaa attgagcagt ttaaaacact aatttcccaa
     2941 gaattgactc cttatgcctc agcaatttta ttggatcctg aatacggact gcctgctgca
     3001 cagaagcgtg cagcagcgag cggtctgctg ttggcatatg aaaaaactgg ttatgatcaa
     3061 accgtacccg gccgcttgcc ggatctgctg tcggactgtt cagttctgcg attgaaagag
     3121 ttaggtgcgg atgcggtgaa atttttactg tattacgatt atgaagaagc agaggaaatc
     3181 aatcggcaaa agcaagtttt tgttgaacga attggaagcg aatgcatggc tgaaggactg
     3241 ccattttatt tagagttatt gtcatatgat gctaaaaatg tagatacgaa atcgctttcc
     3301 tatgccaaag caaaaccgcg caaagtgatc gaaatgatga aagaattctc gaaaacccag
     3361 tataaagtag atgtcttaaa ggttgaagta ccagtaaaca tgtcatttgt tgaaggaaat
     3421 gcaacagggg agatcgccta tacacgtcaa gaagctgccg cttattttaa agaacaaagc
     3481 gatgcaacag atttgccgta tatcttctta agtgctgggg tatcagcggc attattcatg
     3541 gagacattgc gttttgccaa acatgctggg gcacgattca acggtgtact ctgtggcaga
     3601 gcaacttgga aagatgcagt cgctcctttc gttgaaaaag gagaagcggc aactttagaa
     3661 tggctgacag aacaagggac acaaaacatt cgtcaattga atgaagtgat aagagaaact
     3721 gccatcccat ggtatgagaa agtaagtgaa agcacttgtt aatgtttcta atatattagt
     3781 agtgataaga gatatgtgtg attataattt atcattattg aaactgggag gatattttat
     3841 atgaataaaa gattgttaga ttattcagct tcagattttt tgaaagctaa gccgatggaa
     3901 ttaaagcagg caattttggc ttctgaaggt agaacaatta tggcagaaaa tgtgccaagt
     3961 agctgtcctt acatgggaaa atcagtgaca aatgcagaat tggagagagc tgctggagct
     4021 gatttaattt tgtttaatgc actagatctt tttaatcctc aaatttcagg tgtaccttta
     4081 actctaaaag agaatccaat aatctggatt aaaaaagctt taggaagagc tattggtgta
     4141 aatttagaac ctgtagacaa agaagttttg atgagtgaaa atcgaactga aatttcaagt
     4201 ggtagaatcg tttctcctga gactttaaaa aaggcaaatg aattaggctt taattttatt
     4261 tgtttaactg gaaatccagg aacaggagta tctaatagaa ctattgagaa agcaataaca
     4321 ttatccaaat caatttttaa tggattaatt atcgctggaa aaatgcatgg tgctggtgtt
     4381 gatgaaccaa ttatgaactt agatatagca aaaagattta ttaaaacagg tgtagatatt
     4441 ttattagttc ctgctccata cactgttccg tatttcatgg aaagtgattt gcgaggaatc
     4501 gttgattata taaaagattt taatagaaat aaatctattg aggaaaaagt tctagtacta
     4561 acggctaatg gaacaagcca agactcttct gaccaagaaa ctattaaaaa aattgcatta
     4621 gcatcaaaag catgtggagc tgatattcaa cacatagggg attctttaaa tggtatttgt
     4681 cttccagaaa atatttttgc tttgggtcaa gcaattcggg gatatcgtca tcaaattatt
     4741 atgttaggaa aatctaatta tcgttaatta aggaggaaat gaaagatgat cgacaaagtt
     4801 caaaaaatag ctgcaaaaat tagtaatcaa agacatctac tagctttaag agacagcatg
     4861 gctgcagtta tgccattaat cattattggt tcctttttta tgttattagc aaatttcccg
     4921 atagaaggat ttacaaaatg gttatctgaa attggagtac aatccttttt gaacaaagca
     4981 tcagattcaa catttggtat tattggatta gctgttacct actctttggg acacaatcta
     5041 gcaaagactt atggtgtaga ctcattatca gcaggattat tatctttgag tggatatgtt
     5101 ttacttacac ctttattgga tgcagatggt tctataggat ttccaacaaa atactttggt
     5161 acctcgggtc tttttgttgg tattattgta gcacttgtat ctacagaaat tttccggtgg
     5221 tttgtactta aaaatattac aattaaaatg ccggcaagcg ttccaccaaa tgtaagccga
     5281 gctttcgttg ctattattcc tggctttttt gtcgttctac tatggtttat tgttgttgta
     5341 atttgttata aacttggaat tgaaaatgtt catgctctta ttgcagatac actcgcaaaa
     5401 ccactatctt tactgacgaa aactttacca ggaattatat tggttatact tattcaatgt
     5461 ttcttttgga tgtttggtat tcatggtgca caggtaacgg ggccaataat tgaaccgtta
     5521 ttattgcaaa actctgatgt aaatagaatt gcttatcaag ctggaaaaga acttcctaac
     5581 attataactt atgaattctt atataacttt gttttttctg gtggtgcagg ttgtttattt
     5641 gcacttgcca ttttaacatt tttcttttca aagagtcagg aaaataaaac tttaggtaag
     5701 ttatcaatcg ctccagtaag ttttcaagta gcagagcccc ttctatttgg gtttccaact
     5761 atattaaata taaaaatgtt aattccattt gtaactgcac cagtagtaac aacattaatt
     5821 acttattttt caatgagtat gggattagtt gcaaaacctg taggagcaac aatcccatgg
     5881 acaactccac cgataattgc cggattttta gcttctggtg gacgaataag tggtgcagtg
     5941 attcaagtaa taacaattgc aataaatgtt ttgatatact atccattctt taaattagat
     6001 gataatgcca agctaaaaag cgaaaaaaat gattagaact acctatatgt ttctaactgt
     6061 agtta
//
LOCUS       DADGKS010000127         6062 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.132, whole genome shotgun sequence.
ACCESSION   DADGKS010000127 DADGKS010000000
VERSION     DADGKS010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6062
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.132"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..597
                     /locus_tag="JXV47_002774"
     CDS             <1..597
                     /locus_tag="JXV47_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAX1488770.1"
                     /translation="ALGKDPDTWDEFDNAQMQRVPLMIHMPGYTKGTVNHEYGGEIDV
                     LPTLLHLLGIDDKDYLHFGTDLLSSQHDQVVAFRNGNFVTPKYTVLGGKAYNNQTGEI
                     IDTKAAGIDEEISKDQEKVKTALSLSDKLNQENLLRFYVPNGFETIDPKKYDYKNEAE
                     RNEAIEKQKGEHSTSVFSKNGNKTTTILYPVTGTNAEQ"
     gene            831..1697
                     /locus_tag="JXV47_002775"
     CDS             831..1697
                     /locus_tag="JXV47_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1488771.1"
                     /translation="MYDGELIKKLRVNKKLTQTQLAEGICSKTSLVGIETNSVKKVSF
                     GTLKSFLERMNMTLAEYEWIRNQLDEPKKLKKKRRMLDRIQEDSFDPYKEIANNRRHY
                     KKTEDLYYLVLNLHMSKKTEVSETEFEFLRYECRIIEEYLMQVPEYGQFEVSILADFP
                     WIFSDRFIENNYLKIKKRMRRIAQLNNHEQYLFTFLTNLTLFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKSENHQEFFAVIEYTLGKNQRNSL
                     EKKLLAIAKPSS"
     gene            complement(1719..2156)
                     /gene="ndk"
                     /locus_tag="JXV47_002776"
     CDS             complement(1719..2156)
                     /gene="ndk"
                     /locus_tag="JXV47_002776"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HAX1488772.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFATMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKGADAVPGTIR
                     GDYALPGTENIIHASDSRDAATKEIARFFPPFDTNKPSEKAAK"
     gene            2816..5494
                     /gene="mgtA"
                     /locus_tag="JXV47_002777"
     CDS             2816..5494
                     /gene="mgtA"
                     /locus_tag="JXV47_002777"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HAX1488773.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASPNGLS
                     EEQIERSRETYGENAISYGKKTPFIIEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGEYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNDTLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEAAETLDTDTINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVAPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELITGEKISEMNDHELAQVAEEHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGKFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQQVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKIPFIQSNATFAMLVITTLGIIVGSVLPFTGFGAELGLM
                     PLPGNYWLWFFITVVAYLALVTAVKKIYIRRFQELL"
     gene            5582..>6062
                     /locus_tag="JXV47_002778"
     CDS             5582..>6062
                     /locus_tag="JXV47_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAX1488774.1"
                     /translation="MKGAIFDLDGLLVDTERTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KKWKQSFDILVQAAGSPEKVQEVRAKREEYFYQQLTSGAIQLKPYAKEILTDLKERHM
                     KLGIATTTVTKRATDILDHFQLADYFDTFTFGDEVSENKPSPVPYLTALERTGLEALS
                     "
BASE COUNT         2005 a         1030 c         1309 g         1718 t
ORIGIN      
        1 gctcttggta aagatccaga tacatgggat gaatttgaca acgcacagat gcaacgagtg
       61 ccattgatga tccatatgcc tggttatact aaagggacag tcaatcatga atacggtgga
      121 gaaatcgatg ttttgccgac attactacat ctattgggaa tcgatgataa agattatctt
      181 cattttggta cagacttatt atcttctcag catgatcaag tagttgcttt tcgaaatggg
      241 aactttgtga cacccaaata caccgtccta ggaggaaaag cttacaataa tcagacagga
      301 gaaatcatcg atacgaaagc agcaggaatc gatgaggaaa tctccaaaga tcaggaaaaa
      361 gtcaagactg cgttaagtct ttcagataag ctgaatcagg aaaatctctt gcggttttat
      421 gtgccaaacg gatttgagac gattgatccg aaaaaatatg actataaaaa cgaagcggaa
      481 cgtaatgaag caatcgaaaa gcaaaaaggt gaacattcga ccagtgtctt ttcaaaaaac
      541 ggcaataaaa caacgactat cctatatcca gtaacaggaa ccaatgcgga gcagtaaaaa
      601 aatgatcaat aaacaatcaa accaaccttc agggattaga cagcagtctc atgcttgaag
      661 gttggtattt tttatgagaa aaacattttt ttattttttt cgtgtatttt ttatttttaa
      721 cgtatctatt tattgaatgc ggaaaattta aattgaaata atcattcctc ttattggcaa
      781 gcattctgga aaagccaagg gttaatttca attaaaaaag gagaactatt atgtatgatg
      841 gagaattgat taagaagctt cgagtcaaca aaaagctgac acagacccaa ttagcggaag
      901 gaatctgttc taaaacttcg ctagtcggga tcgagacaaa ttcagtgaaa aaagtatcgt
      961 ttggaacatt gaaatcattt ttagagcgaa tgaacatgac acttgccgaa tatgaatgga
     1021 tacgaaatca gcttgatgag ccaaaaaaat taaagaaaaa aagacgaatg ctagatcgga
     1081 ttcaagaaga cagctttgat ccttacaaag aaattgctaa taaccgcagg cactataaga
     1141 aaacagaaga tctgtactat ttggttttga atctgcacat gtccaaaaaa acagaagtat
     1201 ctgagacgga atttgaattt ttgcgttatg aatgtcgtat cattgaagaa tatttgatgc
     1261 aagtaccaga gtatgggcaa tttgaagtat ctattctagc agattttcct tggatattca
     1321 gtgatcgttt tattgagaat aattatttga aaatcaaaaa aagaatgcga cggatcgcgc
     1381 aactgaataa tcacgagcag tatctcttta cttttttgac gaacttgact ttgttttata
     1441 tagaaaatgg tcgcttaaaa aaggcacgta gcgtgaatga agatatgaaa cggagtttag
     1501 cgcataaaga aagaagtaca gtgatttatg aaacattgat ggcggattat taccaacgac
     1561 tgatttctgc tgctttaggg gaagaaaaat cggaaaatca ccaagagttt ttcgcagtga
     1621 tcgaatatac attagggaag aatcaaagga attctttaga gaaaaaactg ctggccattg
     1681 ctaaacccag cagttagacc aacagtttag gatttgtatc acttcgccgc tttttcagac
     1741 ggtttgtttg tatcgaatgg cgggaaaaag cgggcgatct cttttgttgc agcatcacgg
     1801 gaatcagaag catggatgat gttttcagtc cccggcagtg cataatctcc tcggatcgta
     1861 cctggaacgg catccgcccc ttttgttgct ccgaccatct tacggacgat atcgatcact
     1921 tcctcgccga ccagcacaag ataaacgacc ggaccagaag tcatgtaatc gataagctca
     1981 tcaaaaaaac tacgttcagt caagtgctga taatgttctt ttgctagttc aggtgtcatc
     2041 gttgcaaatt tcatttcagc aatggccagt ccctttgctt caaaacgttg gatgatgctt
     2101 ccgaccaaat ggcgtcttac gccgtctggc ttgataataa caagtgttcg ttccataaca
     2161 gcacctcgtt tcctactata attctattat agcgggaggt ggaaaatgag acaaataaaa
     2221 ctgcgtgaga caggaaatat aacgcgtgta ttttaaaaaa gtatgaaaaa catggaaaat
     2281 tgatttgaca tcctcttttt tagttgttat attaacgagg gaaaaccgaa taggatttgt
     2341 taggtgaggc tcctatacaa acataggcta ctgcccaaaa acgtcgagag acgccaatgg
     2401 gtagaacagg aattgtcgag ataaggcttt tcataaggta gctaaaaaca gatatctgct
     2461 ttttacgttg tacagtgtca aaactcaacg atgagatctg agaagctttt tttgatttgc
     2521 tttttcaaac ctttcgctga gtatttggcg agaggttttt ttgttgccgc aaatcccata
     2581 ggtgaaaaaa caaaaaggga ggtgagcgag ttgggaaaat aactattcga aaaatgattg
     2641 gaagtcatga attaaaatta cttagtaaag gagatgagaa caaatggatg acagtcattc
     2701 gaaaaacaag gatttagagg aaaggccagg gctattatct atctgttctc agcccctttc
     2761 agcattttct ctatcgatcc gatgaatagc aaaagaccaa aaacagcgag aacagctgtc
     2821 ttttggacac aaaggagaga tcgagatgga aaaaaagaaa gatacacaaa aaatctatgc
     2881 agcttttgct ggaaaaacga agcaagaatt atttgaattg ttccatgcat caccaaatgg
     2941 attgtcagaa gaacaaatcg agcgttcaag agaaacttat ggtgaaaatg cgatttcata
     3001 tggcaaaaaa acaccattca ttatagaaat attgaaagca tacatcacac cctttacatt
     3061 agtgttgatt gcattaggaa ttatttcatt cattacggaa tacgtattag ccgctccagg
     3121 agataaagat ctctttggtg tagccattat cttcactatg gttatcgtca gtgggacgat
     3181 gacgttgatc cagtctgtgc gttctaatca agcagctgaa aaactgaaat cacttgtgaa
     3241 agtaacggca gctgtcaaac gaaatggcga gtatacagag attcctatgg aagaaatcgt
     3301 ctgtggagat cttgttcggc tttcagcagg agatatgata ccagcggata tgcgtttatt
     3361 gtccgcaaag gatctattca tttctcaagc agcattgaca ggggaaagct atccagtaga
     3421 aaagcatgcg aaagtatgtg aagacgatca gcaaagtgaa acaagttatg aaaatcttgt
     3481 ctttatggga agcaatgtca tcagtggaag cgcggaagga atcattgttt ctgtcggaaa
     3541 tgacacacta tttgggcatg tagcagaaac gctatctgaa aaacccatcc aatcaagttt
     3601 tgaattaggc atccacaaaa catccatgct gctgatcaaa tttatgtcat tgatggctcc
     3661 agcagttatc gttatcaatg ggcttacaaa aggagattgg ttagaagctt ttctttttgg
     3721 attatctgtg gcagttggtt taacgcctga aatgcttcca atgatcgtta cgacgaattt
     3781 ggtcaaagga gcaagtgtga tggccaaaaa aggaacagtc atcaaaaatt taaatgctat
     3841 ccagaatttt ggtgcgatcg atgtgttatg tacggataaa acgggaacat tgacacaaga
     3901 caaaatcatt cttgaatatc atatggattg tgaaggaaat gaagatgatc gtgttttgcg
     3961 ccatgcttat ctaaacagct actatcaaac agggctgaaa aatttgttag atgtggctat
     4021 cattgatgaa gcagcagaaa ctttagatac agatacaatc aattatcaaa aagtagatga
     4081 aattcctttt gattttgaac gtcgccgtat gagtgttgta gtcgctgatc cggctggcaa
     4141 aacacagatg atcacaaaag gcgcgattga agaaatgttg aacatttcta aatttattga
     4201 tcttggtggt actgtcgcac cattaacaaa agaacgaaaa gaagcggtgc ttgcaaaagt
     4261 acaatcactt aatgaagacg gcttacgagt gattggtgtc gcacaaaaga ccaatccaag
     4321 cgttgttgga gaattttcag tcaaagatga gtcagacatg gttctgattg gttatcttgc
     4381 tttccttgat ccaccaaaag aaacaacaaa acaagcgttg aaagctttaa aagaacatgg
     4441 tgtagctgta aaagttctga ctggggacaa tgaattagtc acacggtctg tgtgccgtca
     4501 agtaggccta gaaatcaatg aattgattac tggtgagaaa atctcggaaa tgaatgatca
     4561 tgaattagcg caagtagctg aagaacacga agtattcgta aaattgaatc ctcagcaaaa
     4621 agcacgattg acgacagctt tacgtaaaaa tgggcatact gtcggatttt taggagatgg
     4681 tatcaatgat gctccagcaa tgaaagtggc tgatatcggt atttccgtgg atacagctgt
     4741 ggatatcgca aaagaatcag cagacgtgat ccttttagaa aaagatttga cgattttgga
     4801 aagaggcctt ctttctggaa gagaaacttt tggaaacatc atgaaatata tcaaggcaac
     4861 agcaagttct aattttggca atatgttttc cgtactgatt gccagtacgt tcttaccatt
     4921 tttaccaatg ttgcctttgc aacttctatt tttgaatctg atctatgacg tttcttgcat
     4981 ttccttacca tgggatcgga tggataaaga atatttggat gagccaaaga aatggaatgc
     5041 atctagtatt ggaaaattca tggtttattt tggtccaaca agttcgattt ttgatatcac
     5101 tacttacttg ttgatgtatt ttgttatttg tcctgctgta gttggtggaa gtttccatac
     5161 attggatagc tcacaacaag tgatttttat cgcattattc catgcaggat ggtttgtcga
     5221 atccctgtgg acacaaacat tagtactcca tgcattgcgt acaccgaaaa taccatttat
     5281 ccaaagcaat gcaacatttg ccatgctggt tatcactaca ttaggaatca ttgtcggttc
     5341 agtccttcca ttcacaggat ttggtgctga gttaggcttg atgccgctcc ctggcaatta
     5401 ctggttatgg ttttttataa cagtcgtcgc ttatctggcg cttgtgacag ctgtgaagaa
     5461 aatctatatc cgtcgattcc aagaactctt ataagtgatg cggctgggct ctatgcttct
     5521 gttcattttg gatcagtcat gctaaactag gtgtattgtt ttggaaagga ttaatgtata
     5581 gatgaaaggt gcaatatttg atttagatgg tttgttagtg gatacggaaa gaacgtatcg
     5641 ggatggttgg ctttggggat tccagcaatt tgatattcat atcccgaaag aaatcgttga
     5701 cgcttggggc ggaaaaaaat ggaaacaaag ttttgatatt ttagtgcagg cagcaggcag
     5761 tcctgaaaaa gtgcaggaag tccgagcaaa gcgtgaagaa tatttttatc aacagctgac
     5821 aagtggagct atccaattga aaccctatgc aaaagaaata ttgacagact taaaagaacg
     5881 tcatatgaaa ctagggattg ctacgacaac tgttacgaaa agagcaacag atatcttgga
     5941 tcactttcaa ttagccgatt actttgatac gtttacgttc ggagatgaag tatcggagaa
     6001 caagccttca ccagtccctt atctgacagc tttggaacga acaggattag aagctctttc
     6061 ag
//
LOCUS       DADGKS010000128         6038 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.133, whole genome shotgun sequence.
ACCESSION   DADGKS010000128 DADGKS010000000
VERSION     DADGKS010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6038
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.133"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..488)
                     /locus_tag="JXV47_002779"
     CDS             complement(<1..488)
                     /locus_tag="JXV47_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488775.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGG"
     gene            complement(498..1658)
                     /locus_tag="JXV47_002780"
     CDS             complement(498..1658)
                     /locus_tag="JXV47_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAX1488776.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            complement(1658..2344)
                     /locus_tag="JXV47_002781"
     CDS             complement(1658..2344)
                     /locus_tag="JXV47_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HAX1488777.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            complement(2307..3485)
                     /locus_tag="JXV47_002782"
     CDS             complement(2307..3485)
                     /locus_tag="JXV47_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAX1488778.1"
                     /translation="MGIFQKAVGYFTKKATVTLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            complement(3505..5199)
                     /locus_tag="JXV47_002783"
     CDS             complement(3505..5199)
                     /locus_tag="JXV47_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAX1488779.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            complement(5177..5491)
                     /locus_tag="JXV47_002784"
     CDS             complement(5177..5491)
                     /locus_tag="JXV47_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HAX1488780.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            complement(5594..5875)
                     /locus_tag="JXV47_002785"
     CDS             complement(5594..5875)
                     /locus_tag="JXV47_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488781.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVDIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            complement(5880..>6038)
                     /locus_tag="JXV47_002786"
     CDS             complement(5880..>6038)
                     /locus_tag="JXV47_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAX1488782.1"
                     /translation="VKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKIESFA
                     NFDASERW"
BASE COUNT         1763 a         1259 c          856 g         2160 t
ORIGIN      
        1 cctcctgaat tagtgtttat agtttccaaa gattctactg taacatttac aatgtttgcc
       61 atatctttta gaatattttc tccgttttca cagcttctaa tataatcaag acttagataa
      121 ctacagcagt cgctacaata ccaaacatca tctttagaag gcaatttgcg caaattaatt
      181 cttttattga aaatgacatc cgaatcgata tagaaatatc ggtcgtcctc acgcgaatga
      241 tcttcttcta aatatttcca ccataaatat ggtttaatcg aaggaatata ctctttgtcg
      301 tcccgcagat catcgtacac atgaacttca acaccatatt ccttctcaaa aaaaatagga
      361 atctgatcat cgtgtctgct gaaaagcaat acgatatctt tgattcctag tttcttcaga
      421 ttagttaaac aaacttcaag ctcccattta aaccgattga ttgccggctg acaaagaata
      481 tacttcattc tgatcaccta cgcttgtgtt gtagttgttg tggttgttgg ttttgtagtt
      541 gtagtagtag ttcccaaagc gctaatatct aatacaatga aactatcgtt acgtttaggt
      601 tgaccgtttg catattgttt agctagataa atgcgttcgt cttcaacaaa atggtattca
      661 tctgaagctt caatttttag tgtagatcct acacccatga agtaatctga ggctacccca
      721 ataactgctt ttccttctgg cacagccgtt gactgcaaat ctgaaactgg tactggcaat
      781 acttgtacgt attctccatt agcagttagt acagtcttag ctgggaatac tttagaccag
      841 taatcagttg gattcacaat taggaccaca tcagaaggat tcacattacg ataaatcgga
      901 tcattcacac cttcgatatt gaattttgat agtcgcgcca tcaaaccgcc catagttaca
      961 gcatctaaag ctgtaatagg ttctgctttt ttttcagcat attctccgct agtttgtttg
     1021 ctcatgtcac gcatcattcc gactggcata tctttaccag taccatcaac aattgcttgt
     1081 tctaatgcaa ttctcaatga ttctactaaa acagtacgga cataacgatc taaccatact
     1141 ggacctaaat caagcattgc cttacataca ggaatataac ctgatagctt gaactgcttc
     1201 atgttaatta catcaaagcc attatctaaa acttttttaa cagcttcgca aagtttaccc
     1261 caccatgctg gattgactcc acgtgacaca atccattctg ttacaccagt tgtgttaaca
     1321 aaagtaattt tttgcaatag tggatgagat tgttctaaat cttcaaatac acgttcaaat
     1381 acagtagctg gcactaattc ttcgacccct gcaaaacctt cgtttttcac tacttcgtta
     1441 tagaattttg tttcttgtgt agttaataca cgctgaccac ggttcattaa tactaattga
     1501 tcttgatttt ttgctgttgc ttcttctaaa attttatcct gaatttcctt agataagctt
     1561 accatagctg cgctaaaaga ttcttcgtta ccatctttaa aagctttcat caattggtcg
     1621 cttgcagctg ttacaccttt taaattttta actgtcatta ttttacatct ccttgtccaa
     1681 atgttttatt taatgctgct gtaaatgcag caattttttc tgctcttttt tctttaacgt
     1741 cattcaaaat ttcttcaacg ctttgttctt ttttagcttc agtacctgag ctattttctg
     1801 catcgataat ttcatcgacc aatccataac tcaaagctgt ttctgcatcc ataaacgatt
     1861 ctttttcaag aagttcttgc aatgcttcat ctgtgccatt gaatcgtgtt ttatatgaag
     1921 cctttaccga tttatcaatt gattccagtt ggtcagcaat cgtacggaag tcatcgacat
     1981 ttccttctcc gtatgtggaa gcgcggtgaa tcatcaattg tgcattgttg tagattttta
     2041 tagtatcgcc agccattgcg ataattgaag cagcactagc ggctaagccg ttaatcacaa
     2101 cgttaacttt tgctttattt gacttaagta agttcccaat agcaatccct tgaaatacgt
     2161 ctccaccgtt tgaattaatt actacttcaa tttcttcttg atcacctaga ctatccaaaa
     2221 tatttttgat tcccttgtca gtattccctt caaagaacca actagaacca ataaatccct
     2281 gaataaaaat ttgcggtact gcgccttcat tctttactgc tagaaatgtt ttcattgtcg
     2341 tcattcgcct cacctccttt cgatacttgt tgattgtttt tagttataaa tatttcatct
     2401 gccatcgcct tatcagagcg atcatttcca acgcgttctc ttccttcgtt gattgtaaat
     2461 actccatttc taatgcctac atcaatagcg tcaaccaaat ctttgaagct agtaatcttg
     2521 atcatagttg tatccacacg tacaaaattc cctgacaagt attcttctac ttcatagaga
     2581 ctagcgttaa acgcatcctg aataagttca gcaatcggta tgatttcgaa cattaaaaaa
     2641 gcgtccactt gatccgataa cccactcatg tctcccttta gtaggttttt cggaacgtga
     2701 aacgctgctg ctgtcatctc aaagatgtcg tctattaagt tttttatatc tcttgaattg
     2761 ctttggaagt ttccgctgaa atcttctaat gtgtactcat tttgtaattg aaataccgca
     2821 cctgcattat cagcttccat aaaagcctta aattgtgatg tcatcatttt attgatttga
     2881 tcttgtgttg tattgtcttg cggtcggaat aaattccctt tcagtacgta tctacgagcg
     2941 ttagagcgct tgtaaacatt catggcacta gaaatgagtt tcccatacgc ttgataatac
     3001 gcatcgacta gttgcctaat ttgttgatct gcgtatttta tatagataac atcactttct
     3061 agaaattctc tatcaaggac tatgttgtta atttgcactt gagaaaacac atcatctttc
     3121 aatgcatatt ctgtgacatc ccaactatcc gcaataaata tttcgctaga attattagac
     3181 ggagaaacga tcaatacttc attgtagaat attaatctcc tgatcagttt ttttctaaat
     3241 tctgttgcat tatttttctt attaggagct acattcagcc tatagtaaag atcattcttt
     3301 ttattttttc catcttcata tgacttgaat tccgctttac tcatcgcatt tgcaatcaaa
     3361 tcaatacaag tttcaatcgc aaattttcga tacacaaaat caacttgcaa tttacaaaag
     3421 tattcttcta aagtaaccgt tgcttttttt gtgaagtatc ctaccgcctt ttgaaaaatc
     3481 cccactttct cacctccttt caagttagaa tactagagga gtaaatccag ttcctgtatt
     3541 ttctactgag ctatttgtga ctgttacagg agcagaatca taaatatcat ctaaaaaatt
     3601 caaaccatga aggaatgaaa aaaagccatc cgtttttcta gtttcaggtt ctattttttc
     3661 atagcgtata tttccattag aaatatgctc ttcatataca ttcatgcaat accaacgcat
     3721 aatcgcatcg tcaccaaaaa ataaacgttg attaataaaa aggtcatcaa ccagatcttt
     3781 taacatacca tgtgtaacag atccgcttcg aacaatttcc acagtaaaac ctgcttcttc
     3841 taaagcgggc ttcaatattt ttgcacggta catatccata gcgatttttt taatataata
     3901 tttattactc atttcaagaa accaacctac aatataatca gcttctatat tttttccatg
     3961 aacgatctgt gattttcctt gatctataga aatatctata acctctcgtt tgatgttttg
     4021 taatcgaagg gctgattcgt ggataaaagt atgttgtgta aaataaacat ctttatcgta
     4081 ttttcctagc aacccaacgc tggcaaaatc tcgtctatca gcaaaatcga ctgttcctat
     4141 cacttcatcc attttttcag gaaattcttt ttctttcgta tgcagaacat catcatatga
     4201 agcaacagca aatcgtgtat cttccatagg tctgttcatt cgtttggtca tgaacgtaag
     4261 tcttaaacca gcattacgtt gcatttgaga gtattcttga aacattttcc gttttaaatc
     4321 tgcattgtaa ttaatagttg gacaagcttt ttcccacatg tcgggatcat caacttcatt
     4381 atcgttatcc aagcgacaaa taaatggaaa caaactagaa aattctgctc catccttgtc
     4441 aattccaagt tctccagaaa gaatcatttt tgattcttct ataatgtcat caagcggacc
     4501 accacgaaca tgaccattag ttgtatcata aaattctcta taatctcgaa ttttaccacc
     4561 accagaagta gccacattta tcattgaata atcttcattt tcgtgaattt catcaaagcg
     4621 gtttgcacct ggtcgcttcc catcttttgt tctagcattt gccgtgttat aacgaagttt
     4681 gctgtttgta gcgatatttt gaataacttc cttcgtagct ttaaatactt ttttatctaa
     4741 atcaggatga tctttaatta ctttaaatac atcatcaaaa ctagtctttg cttggctttc
     4801 attattggca tagatatcaa tatcataatt tttaataccg tgtttagcgg ttagtagaaa
     4861 gaagttgttc caagaagcaa aaccagtttt accattacca cgtcccatta atgaaagata
     4921 tctattgaac actagtgttt tatctttttt ccatcgaaca ccataaataa aacattgtag
     4981 aaatttttcc cacggaatta attcgaatgg aaagtattgt gctggtatat tgattgaatc
     5041 ctctaccatc tgcttatcga agtaaatatc ttctctagta aagactcttt cttctagata
     5101 attttttagc aataattgct ctttgcatac cttgatagtg ccttcttcta tagctttgaa
     5161 ccaattttca atatgcttat aactcaggaa ttgattcatt tgcttcacct accaattcag
     5221 gagtaatggc aagtttatcc aacatcaatc ccatttgttt gttgacagaa acaagcaacg
     5281 ctactgattc attcttttta ccattctcca gtctaatgcc gttctcggat atatcttctt
     5341 ccagtgatat cgccgtttcc cataaactga tataacgatc aacattatct aagaatggct
     5401 caatatttgt tttctgactt tccaattggc ttattaaaga gcggcgtaat ttttctctgt
     5461 agcgattttg agacaattcg tttttaaaca ttttagccct cctttcatga taaagttcga
     5521 aaaaatctct tttcctgaca gccccctccg tttcatcacc cccaaaaaat ttgcgattta
     5581 ttttaagggg gggttatctc accatcggaa tgaaagcttc agcgaagtca atgtaataat
     5641 taatctcttc aatactatat ccaaaaacat tttttattct ttcgacgtta ttatctttat
     5701 tcaacgcttc tcttacttga ttcactttgt atttactaca acagttatct gataacagat
     5761 ccctaatatc tacatagcga acgtatatca aacgtttaat taatccctga gtataagatg
     5821 aatactcttc aatcttttct gtatcatact ctctgccatt atcattgatg atcatgcact
     5881 taccaccttt cacttgcatc gaagttagca aagctttcta tcttcttctc ttgtttatct
     5941 aatgctgtaa gatatctgcc atgaacttca ttatgatgtt caacacataa acaaataaga
     6001 ttatctaaat ctaaagctaa gtcaggtcta tccttgac
//
LOCUS       DADGKS010000129         5979 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.134, whole genome shotgun sequence.
ACCESSION   DADGKS010000129 DADGKS010000000
VERSION     DADGKS010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.134"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            176..1072
                     /locus_tag="JXV47_002787"
     CDS             176..1072
                     /locus_tag="JXV47_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HAX1488783.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(1222..2163)
                     /locus_tag="JXV47_002788"
     CDS             complement(1222..2163)
                     /locus_tag="JXV47_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAX1488784.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            2289..3410
                     /locus_tag="JXV47_002789"
     CDS             2289..3410
                     /locus_tag="JXV47_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAX1488785.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            3668..5170
                     /locus_tag="JXV47_002790"
     CDS             3668..5170
                     /locus_tag="JXV47_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HAX1488786.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            5237..5764
                     /locus_tag="JXV47_002791"
     CDS             5237..5764
                     /locus_tag="JXV47_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAX1488787.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
BASE COUNT         1972 a         1042 c         1245 g         1720 t
ORIGIN      
        1 aattacaact attcagaaaa cttttaggcg aattttaata gaagaatgat ttatttcatc
       61 atattttcat acaaatgtta aattttcata caaatatagg aaacgtttta ctggcttttt
      121 actatttaaa caggctatca taggaaaaag tgacagagaa agtgaggcgg aaaagatgaa
      181 caaaaatgac gtactgctag ttgcaaaaaa taaatcactt tattttttgc cttccatccg
      241 ctctttagat gtttggtccg gaaaagattt actacagtcg gaattcatta aatcagctag
      301 acaacagttg gcaaattatc agctgatcgt ttttttagat tatggatttg atatggagat
      361 ggctcgacgc gtgcgcccat ttaccaatgc aaaaattgtg ttattttttt ggaatcactt
      421 caaagcagaa cacgaggcga tgctgaagca ggcacaagat gaaccggcaa tcgatgagat
      481 ttatcatttt gattttttgg aagcaaaaga acttgggctg aaacataata gttcatttta
      541 ttcgaaacat atgaattttt cttctagcga accaaagacg gatctatttt ttggtgcaac
      601 gaataatggg agaaaagaac gagcagaaag ctataagcag gaatttataa aaagagatgt
      661 tacgaccaac tatttcattc ttccacatcg agggaatgaa caacctggat atcttactta
      721 tgaagagtac ctgaaaaaaa caggggaatc gcgcgggatt ctggaactgt tgcgggaggg
      781 tcagcaagga gtgactttgc ggacatttga atccatgtat tttcaaaaga aactagtgac
      841 ggataatcaa gcgattgctc attatcattt ttatcgtcct gaaaatattt ttttgcttcg
      901 agaacgtgat ttagatgaat taccggaatt tctgcataca ccatttaagc caatcctatc
      961 agagctattg gaattttatg atgcagaaaa ttgggcaaaa cgatttatca ctaacgattc
     1021 cactatttat gagcaatacg aatatgacct ctcctctgtt gaaaacaaat aaaaaaccta
     1081 cattttgaag agattatgta ctgaaacaaa caagcacaat tcttatggca tcatgagagt
     1141 tgtgttttct ttttgatctt ttattgggct taaaaaaaga gaaccagctg ctgattcagc
     1201 tgattctcat cagagagcct tttattctgc gccaaggatt ccttcttttg catggactaa
     1261 ttgggtcaaa aaggcacaat atggtgtagc aatatcatat ttttgtcctt ttcgccaaat
     1321 ggcaccattg atgtagtcga tttcagtcaa acgatggttt ttgatcaggt cttggtacat
     1381 agatgggtaa tgcaacccga tgttgtcagg atcataagta gaagcaatat gttggtacac
     1441 ttcttcttga tctagtatga ttccttcttt tgctgcgata gaagcaaatt cagatacgat
     1501 tgttcgaacc atgctctctg ccgctttttg cgcgcctagt tcagcaatat tacaatccaa
     1561 aatcgtgcat aaaccattca atgttccatt tacacaagct tttcgccaaa tggaataacg
     1621 aacgttatgg ctatagatcg gatttaaatt tgcttcttga aagacttcta caactttttt
     1681 tgtaaatgct tcgccttctg gttccaagtt ctctagttcg atttctccat cacctaacaa
     1741 tgtgactttt ccgggaccag ctagaccagc tgtccacatc gtgatcccaa ataagatatt
     1801 tttctttggc acatattttt ccagtacatc ttcatgacct aatccattta gtaaacacaa
     1861 aacataagta ttgtcagtaa taatggattg gatcgaacaa aacatatcat ctaattgatt
     1921 ggcttttgtt aatgctacga tcaagtccac gtgttcgttg ctttcgatga tttcttctgg
     1981 tgaatagatt ggcagttttg cgaccacttc tttaccgtta aagtcagcaa tcaacccatt
     2041 tgtacgaatg gcttcaatgt gagcaggcca acgatcgatc aagaggacct catttccgct
     2101 ttgatgtagc atcaatccga ttcggctgcc cattgctccg gccccagcta ttgcgatttt
     2161 catgtttttt ctctccttta ttcaatgagt tcccttttag tatatagaaa aatggaagaa
     2221 aatagcattg ttttgtttga aaaaaatgaa aaaaagtgtc ttacttaaga agaaagtgag
     2281 ggatacagat ggatattttg gcggcaattg attcatttaa aggaagtgct tcttcatttg
     2341 aactaaatca ggcagttcta aatggctggg aagatcgtaa aggaagaaaa atcaatgtgc
     2401 cgattgcaga tggcggagaa aatactgcag aagcaatcta ttacgcgctc aggggaacat
     2461 ggcgtaccat tgatgggatg gatctcttat tccgtcagcg aaaaatcagc tatttattga
     2521 caacttggca aggaaaaaac accgcagtca tcgaatctgc acaagcattg gggttagatc
     2581 tacttgataa accaacggat caaactatcc gacttgcttc cagttatgcc ttaggagaac
     2641 ttattaaaga tgcactgctt caagaagtag aacaaattat tgtcacttta ggaggaagcg
     2701 ggtgtagcga tggtggtcta ggattactcc aatccttggg tgcttcttta gaagggtaca
     2761 cagaaggaaa tcctttatta tctactaaaa aacttcattt tgatcgaaga aacgttcttg
     2821 tttctaaagt aaaattgatt atcgctgcag atgttaccaa tccatataca ggtcaacaag
     2881 gagctgcttg gcaatttgga agacaaaaag gaggaataga tacgacgcta gctttcttag
     2941 ataaacaagc aggaaagatt gctcagcaaa taaaagattt ctgggaggtg gatttagatg
     3001 atattccagg aagtggagca gcaggcggta ttggtggagc cctttttttg ttgggagcga
     3061 agatggtttc tggtttcgat ttagtcagcc aaatcactgg attggaaaaa aagatcgaac
     3121 aagcagatgt catcattaca ggagaagggc ggatcgatca gcaaacgatc cacggaaaag
     3181 ttccatacgg tgtagcagtg cttgcaaaaa aatatcgaaa accaataatc gctatttgcg
     3241 gaagtagaga ccaagagcta gaaggacttt ctgattttct cccaattgtc ttaagtattc
     3301 atttgggtcc aataggttta gaagaagcaa tggaacacag gcaaacatta gaaaaaacaa
     3361 aaatcttagg acagacactt agcagatttt tcaccatcct cccgaagtag ttgacaaaat
     3421 cattttcttt atgctatcgt aatttcaaat ataggacaaa gtgagggatc cgtgcattga
     3481 aaaattaagt cgattgatga aagctgcatt cagactgtac cttgtggaga caaggaagca
     3541 gtgtgcagat tttcgggatt ggcttggttt tttcgatgta tgggtctttt tgtgtgtatc
     3601 caacccttgc atcctcttta gccagttctg aaaataggac tggtcttttt ttacgaggtg
     3661 atggaaaatg tctaaaatcg aaataaaaaa tctgacattc ggctacgaca gccaaggcac
     3721 attattattt gaacaagcaa atctaaattt tgacacacaa tggaaactag gacttatcgg
     3781 acgaaacggt cgaggaaaga caactttact gaatattcta caaaacaaac taccttatca
     3841 agggcaagta atccatcagc aagaatttgc ctatttcccg caacagacaa aagataaaga
     3901 acgtttaacc tattacgtgt taaatgatat tacggatttt gagatatggg aaatcgaaag
     3961 agagctccaa ttgatgcaaa cagatcctga aatcttatgg agagaattca gcacactatc
     4021 ggggggagag aagacaaaag tcctactggc acttttattt gtggatgaca ctcatttccc
     4081 gttaatcgat gaaccaacga atcatttgga tatctctggt agaaaacaag tagcggctta
     4141 tttgaaaaag aaaaaacaag gcttcatcgt ggtcagccat gaccggggat ttatcgatga
     4201 agtagtggac catgttttag caatcgaaaa aagtcaactg gaactttatc aagggaattt
     4261 ctctatctat gaagaacaga aaaaacttcg tgatgaattt gaaatggctc aaaatgaaaa
     4321 attgaaaaaa gaagtcagta ggctaaagaa aacagcagct gaaaaagccg aatggtctcg
     4381 ttcccgagaa ggagataaaa caaagaaaca agtcggattc atcgatactg aatctagacg
     4441 agtgaataaa ggagcagtgg gtgctgatgc tgcacggacg atgaaacgat ccaaagcaat
     4501 cgtgaatcgg atggagaccc agatcagcga gaaagaaaaa ctattaaaag atatcgaata
     4561 tatcgattct ttgacgatga atagccaagc gtctcaccat aagcgacttt taagcgtaga
     4621 agatcttcaa ttagggtatg aaaatctgtt attcgagcca attcatttta caatcgagcc
     4681 tcatcagcgg gtggcgattt caggtcctaa cggtgcagga aagtcatcca ttatccatta
     4741 tcttctgggg gcattcaacg gcaaggttat aggagaaaaa taccagccaa aacatctgag
     4801 cattagttat gcaagccaaa attatgaaga caatcgagga acgttggcgg aatttgcaga
     4861 gaaaaaccaa gtagactacc aagcattttt gaacaacctc cgaaagcttg ggatggaaag
     4921 agatgttttt cataacaaga tcgagcagat gagtatgggc caacggaaaa aagtggaatt
     4981 ggctaaatct ttatcacagc cagctgaact atatacatgg gatgaaccat tgaattattt
     5041 ggatgtcttc aatcaagaac aattagaaca actgatcttg aacgtgaaac ctgccatgtt
     5101 actagtggaa catgatcaaa ccttcctgga taaagtatct actgagatta tttctcttga
     5161 gagaatctaa cccttgtaat ctcaagaaca acaaggtatg gttaagggga actttgccaa
     5221 cgaaggagag aatcacatgc tttatgtaac gagacacgga gaaacaactt ggaacgcaca
     5281 aggattagtt tgcggacggg cagatgtgcc gctgactgaa aaaggacaga tgcaggcaca
     5341 gaaactagca gaaaaggtag tagatttgcc tgttccaatc acgaaaatca tccattcccc
     5401 tcttcaacga gcaagagata cagcacaagc agttgctgat cgtctcagct tgccgctgac
     5461 cgttgatgaa cgattggtag aaatggattt tggggattat gatggactgc caagcaaaga
     5521 tgagaacttt caaaaagcac gtttagcgtt cgctgtacga ttcccaaatg gggagtcagt
     5581 cttagatgtg tatgcacgga tcgttccttt attgaaagaa tgcatcgaag acgaagaaaa
     5641 tgtctatctg ttagtttgcc ataatgcctt gataagagtg atcaatgctt attttcatcc
     5701 gatgcctaat gaggggttct ttacattcat ggtagataat acagaattgg tttcttatga
     5761 gtaattatgt ttttgtgtta tttaaataaa atatttcaag gcactgcttt tgcttagcag
     5821 tgcctttttt aggttatgac aattcttttg ataatataaa ctcaaccttt agaaatgaaa
     5881 tttaattatt ttaataaaag tattgaaatt ttgtttcttt agatatatac tctagtcata
     5941 gaaatgaaga cggatacaga aaaagaggga taatatgtt
//
LOCUS       DADGKS010000130         5965 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.135, whole genome shotgun sequence.
ACCESSION   DADGKS010000130 DADGKS010000000
VERSION     DADGKS010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5965
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.135"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(15..260)
                     /locus_tag="JXV47_002792"
     CDS             complement(15..260)
                     /locus_tag="JXV47_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488788.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(375..953)
                     /locus_tag="JXV47_002793"
     CDS             complement(375..953)
                     /locus_tag="JXV47_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAX1488789.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(1030..1560)
                     /locus_tag="JXV47_002794"
     CDS             complement(1030..1560)
                     /locus_tag="JXV47_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HAX1488790.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(1564..2424)
                     /gene="rlmB"
                     /locus_tag="JXV47_002795"
     CDS             complement(1564..2424)
                     /gene="rlmB"
                     /locus_tag="JXV47_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HAX1488791.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(2417..2812)
                     /locus_tag="JXV47_002796"
     CDS             complement(2417..2812)
                     /locus_tag="JXV47_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAX1488792.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(2809..4221)
                     /locus_tag="JXV47_002797"
     CDS             complement(2809..4221)
                     /locus_tag="JXV47_002797"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HAX1488793.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(4218..4754)
                     /gene="cysE"
                     /locus_tag="JXV47_002798"
     CDS             complement(4218..4754)
                     /gene="cysE"
                     /locus_tag="JXV47_002798"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HAX1488794.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     gene            complement(5076..>5965)
                     /locus_tag="JXV47_002799"
     CDS             complement(5076..>5965)
                     /locus_tag="JXV47_002799"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HAX1488795.1"
                     /translation="GMPTYNFAVAVDDHLMKITHVLRGDDHIANTPKQLMIYEAFGWT
                     PPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPDAMFNFIALLGWSPVGED
                     EIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMDLDAFTDMCLPYLIADGR
                     VAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEHPVLNEAAKEVLAGETVP
                     TVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFMPIRVAVSGQMHGPELPE
                     TIELLGREKSLAHLNQVLN"
BASE COUNT         1526 a         1315 c         1072 g         2052 t
ORIGIN      
        1 ggctcgtttg ctttttaaac tgcttcagtt aaaaattcga tctcaactgt ccgagtaagt
       61 acatctgaat agctgtaaga tactcgttca aaagaatttt cttcaggatc caaatcaaca
      121 acgaatactg aaggataggt ttctgttaaa acgccgcggc gttctgtttg acgctttctt
      181 cctgtctgag caaccaacat gattgggctg ccgatacgac cttctaaatc tttcttgatt
      241 gaagctaaag ttgttggcat acagttcacc tctactatca actataccac atatttttaa
      301 aattttcaag tttaccataa aaaaaaaaga aatgcaataa aaataaataa gaagctcatt
      361 aagatttttc taaattattc ctcattataa aatttcaagt gtttttttat tttgagtttt
      421 actctcccgt aagcgctcat tacttgcttg tgatccattg ctaaacattc agccatgtct
      481 acaaaatcaa cgccttgcat ataataatga aaaattttag cttctatttt tgaaaactgg
      541 atttcgcaat tttcgattgc ttcttttaat aaaagatgct gaattgctaa aggttcttgc
      601 aatgtgatct ctgctaaaaa gtctggtcct tctgtctcta ttttttggtc gattgagact
      661 tcatcttttt gatcacgacg cttcagcgcg ttctgcttcc tcaacagaga atagatttga
      721 ttgcttataa cgcttttata ataacttcca aagctaacac ctttgctttt ttcgtaagtt
      781 ctcaatgcct gatataaagc gatccttgct tcttgttccc aatcctcaga aacataattt
      841 cttaaataat aggtgttttt caaacgtagt aaaagtggaa aatatttttg atacagggca
      901 gcaaatgctt cttcgtcacc attacgtgca gcgcgcaata actcctcaga cataaaataa
      961 ttcctccata aattcgttta tggaggaatc ttatcatcaa tgattcatcg aactgattag
     1021 aacgatatgt tatttatttt ttctcattaa atcgtccaat ttttgggaca atttttttaa
     1081 ctgctcttca ttccatggag aattacgtcg gaaatcaata aaatgcatat ctttattttc
     1141 ttgggctatt gttttttccg ttttttttat cgtcttatat aattcataag cagaagttcg
     1201 taatgctcct tgggaaaaga tcatccactg ttctgctaaa tcgcttgtcg ccactgtcac
     1261 ttgtgtcaaa cggtcattca gctgaccagc gattctctcg atataactgt cagccgtttc
     1321 gtcttctttc gtaaaaacaa catccaactg gtatttctta taattttgtt ggatgcccgg
     1381 aactagttgg gcatcgaaga caacgatgac ttccattcct tcatatttcg cataatttga
     1441 taaacgatgt aaaagagctt ctcttgcatc cgccattttg tcctgctttt taagctggac
     1501 aagttccggc cacgaaccaa tcatgttgta gccgtctaca atcaacagct gttttttcat
     1561 ggtctactcc ccctgacgtt gggaaaaagc ctgatacata agcaaaccag cagcaacact
     1621 ggcatttaag ctctggacgt gcccggtcat cgggatcgtc agcaattcat ccatttcttt
     1681 tttcaatcct ggactcattc ctttgccttc attaccaatg actaaagcaa ttgatccttt
     1741 ggcattccat ttttggaagt ttgtgccggt catatctgtg ccaaataccc aaaatcctgt
     1801 ttctttgagc tgttgcacag cttgtaccaa attcgtcacg cgtgcaacag ggacatgttc
     1861 gactgcccca gtggaagtct ttgttacgat aggtgtgatt ccaactgctc ggtgttttgg
     1921 tatgatcaca ccatcgacgc cacttgcgtc tgctgtccgt aaaatcgacc caaaattgtg
     1981 tggatcttcg atgctatcca aaatcaaaaa gaaggggtct tcttttttct cttttgttcg
     2041 ttcaatcagt tggtcaaggg ataaatattc ataaggtgta atcgcaagaa cgactccttg
     2101 atgcacgccg tgatcgctca aagtttctaa tttttgttta ggaacccatt tgactggcac
     2161 agcttgttca cgtgcgattt ctttcagttc ttctactttt tctcctcgtg aatcttcttg
     2221 aagaaagagt ttattccctc gcccttgttg tagcgcttct actgcggcat ggtgcccaaa
     2281 gacgaaatta tcttctaatg cttcttcatt ttgatcagaa actgactgat ttcgtccagt
     2341 ttgcttttta tttgaatatc tattttgttt tttgtcttca aatccacgtt tcgattgatg
     2401 tttgtttgtt ctttctttac ccattttttt caccaacttt ctgaatacac cagcggatca
     2461 attcttccat ccgctcggtt tgttttgtca aatgcagata gcccatgagc gcttcgaacc
     2521 ctgttgcgac ccgatacgtc gtaacatcag cattttttgc gctcgtatgg cttttagcat
     2581 ttcttcctct gcgataataa agttcttctt cttctgtcaa aagatgttct tccagcattt
     2641 gctgaatcaa aaaggcttgt gcattcgcag aaacataatt cgttgccgca cgatgcagct
     2701 tattgggttt tgtttctcct tgatcaatca ggtggtcacg aacatagatt tcgtaaatcg
     2761 catctccaac ataagccaag gctaaaccgt tcaattgtgt gtaatctctc atgcttctct
     2821 tctccatcgg gttccttgcg gtgtatcttc taataagatc cctttttctt tcaacaaatc
     2881 acgaatttcg tcgcttcgga caaaatcacg attgcttctt gcttgatttc gttcttcgat
     2941 caattgttca atctcttcat ctaataactc ttctgctgta aataaaatac cgaagatcga
     3001 aagccattgc gagaataaag cttctccttg tgccaagaca gcggcagaaa ctttcggctg
     3061 gtctagataa gtgttcagcc acttagcaag ctcatagacc actgtgatcc catttgctgc
     3121 attaaaatca tcgtccattt cttcgatgaa tcgctgttct aaattttcta acaaagcgat
     3181 tttatccgca tcatctgcca aattctctga ggcagtttct tggcggaatt tcaaattgtc
     3241 aaacgtattc ttcagtcgtt gtaaattggt ggctgcttct ttcatcgtcg tttcactgta
     3301 gcggatcgga cgacggtatt gtgtggtcgc catgaagaaa cgcaagactt gtggatcaac
     3361 gtttttgatc atttcatgta cagtgatgaa attccctaga gatttactca ttttttcatc
     3421 gtcttcgcca atcgttacat agccattgtg catccagtaa ttagcgaatt ttttccctgt
     3481 tttcgcttca ctttgtgcga tttcattttc atgatgagga aattctaaat cttgcccgcc
     3541 accatggata tcgatcgttt ctcctaaatg ttttgttgcc ataacggaac attcaatatg
     3601 ccaaccggga cgtcctttgc cccatggtga atcccaagaa atctcgccag gttttgcttg
     3661 tttccataaa gcgaaatcta atgggtcttc tttttgctgc tgttcttccc ctgtacgctg
     3721 acttgctccg acttccagtt catcgatgga ttggtcactt aatttcccat aattttcaaa
     3781 tttacgggta cggtaataca catcacctga agattcataa gcatagcctt tttcaaccaa
     3841 cacttgaata aatgctaaaa tatctggcat atgatccatg actcttggat gcagtgtagc
     3901 aggctcgaca ttcaacgctt tcgtatcttc ttcaaatgct cggatgaaac gatcagcaac
     3961 ttctggtgct gtaataccta attcgtttgc tgtacggatg attttatcgt ctacatccgt
     4021 gaaattcgat acgaaatcga ctttatagcc tcgatattca aaatagcgtc gaattgtatc
     4081 gaaagcaatg gtgctacgag catttccgat atggatataa ttatacacag tcggtccgca
     4141 gacatacata ccgacatgtc ccttttgtat agggatgaat tcttcttttt ttctggtcaa
     4201 tgtattgtag atttttatca ttctgatctc ctcacttttt ctcctttgat tcgaacgact
     4261 tttgctggta ctcctaccgc tgtagcgtcg tctggaacat ctttcaacac aacggcacct
     4321 gcaccgattt tggcgttttt tccgatcgtt accggtccta atatctgcgc attcgcagag
     4381 agcatggctc cttgtttaac agttgggtgt cttttacccg tttcttttcc tgtgccgcct
     4441 aatgttacgc catggaataa aatcacatcg tcctcgattt ctgcggtttc gccaatgacg
     4501 attcccattc catggtcgat gaacacgcca gttccaatcg ttgctcctgg atggatctca
     4561 acaccagtta ggaaacgcca gaattgagca ttgatcttcg ccaataaaaa gagccggtgc
     4621 tgatataaaa aatgagagaa acgatgccaa aacaaggcat gaaaaccagg gtatgtcaaa
     4681 acgatctcag ctgtcgaacg tgcagccgga tcgtttctct ttgctgcatc aatcgctcgg
     4741 gtaaaccaac tcatgacttt ccactccttt cgtaagaatt ttatgtagga aatcatcttc
     4801 ttataaagaa aagaagcgcc ttttaaataa gtttccttat caaaagacgc tttccgcgtg
     4861 gttccacttt tcttcataat caatgattat ctctgacagc taacgcctgt tatacgttct
     4921 tggctacttt gtttcctata aaacagtttt tcctgttttc tgtgtttcgc caagaccact
     4981 cccagaggca tttcggcaac cattcattga taccttgcac cacccggtat ctctcttgta
     5041 atgatcagct gcttactttt ttctgttcat cgtgtttagt tcagtacttg atttaaatgt
     5101 gctaatgatt tttcacgacc aagcaattcg atcgtttcag gcaattctgg accatgcatt
     5161 tgtcctgata cagctacacg gattggcatg aaaagatttt ttccttttac gccagtttct
     5221 ttttgaacag ctttgatggc agctttgaca gttggagcat ctactacttc catttgttct
     5281 agctgtgctt tgaatgcgtg gagaacagta ggaactgttt caccagcaag tacttctttt
     5341 gctgcttcat tcaatacagg atgttcattg aaaaatagcg tagacagatc aacgatttct
     5401 gcagcatagc tcatttgagg ttgatacagg ctaacgatct tcttcaccca ttcgattgtc
     5461 ttttcatctg ggttttctgc tacacgtcca tcagcgatta gataaggcag acacatgtca
     5521 gtaaatgcat ctagatccat tgctttgatg taatggttgt ttacccattg cagttttttc
     5581 gcatcgaaag ctgcgggtga tttacttagg cgttttggat cgaacatttt gatcaattct
     5641 tggtgttcga agatttcgtc ttcgcccaca ggtgaccagc ccaataatgc aataaagttg
     5701 aacattgcat ctggtagata gcctaattcg cgatattgtt cgataaattg caagattgat
     5761 tcgtcacgtt tgcttagttt tttacctgtt tcactgttga tgatcaatgt catatgtccg
     5821 aaggttggtg gtgtccagcc aaatgcttca tagatcatca gttgttttgg tgtattggca
     5881 atatggtcat ctccacgtaa aacgtgagtg attttcatca aatgatcatc gaccgcaaca
     5941 gcaaaattat aagttggcat accat
//
LOCUS       DADGKS010000131         5808 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.136, whole genome shotgun sequence.
ACCESSION   DADGKS010000131 DADGKS010000000
VERSION     DADGKS010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5808
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.136"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(49..2220)
                     /gene="copB"
                     /locus_tag="JXV47_002800"
     CDS             complement(49..2220)
                     /gene="copB"
                     /locus_tag="JXV47_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HAX1488796.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIR"
     gene            complement(2240..4426)
                     /locus_tag="JXV47_002801"
     CDS             complement(2240..4426)
                     /locus_tag="JXV47_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HAX1488797.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEVKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLCLNRHMKK"
     gene            complement(4426..4635)
                     /gene="copZ"
                     /locus_tag="JXV47_002802"
     CDS             complement(4426..4635)
                     /gene="copZ"
                     /locus_tag="JXV47_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HAX1488798.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(4648..5088)
                     /locus_tag="JXV47_002803"
     CDS             complement(4648..5088)
                     /locus_tag="JXV47_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HAX1488799.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYYPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(5162..5701)
                     /locus_tag="JXV47_002804"
     CDS             complement(5162..5701)
                     /locus_tag="JXV47_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAX1488800.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQLFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
BASE COUNT         1503 a         1305 c         1015 g         1985 t
ORIGIN      
        1 tcgaaaaaaa ggttgtgaca cgttttttgt cacaaccttt tttcattatt atctgatttt
       61 caatgtcaaa gcatttagag ctacaactac cgtacttaac gacatcaaga cagcaccaac
      121 tgctggactt aatatgatac caattggcgc aagaattccg gctgctagcg gaattgcaag
      181 aatattgtaa cctgcccccc accagaggtt ctggatcatt ttctttcgcg tttgcttggc
      241 tagatcaaga aaatgcaaaa tatcttttgg atcgctgttt gtcaatacga catccgcaga
      301 atcgattgcg atatctgtcc ctgcaccgat tgccatcccg attgaagcac gggctaaact
      361 tggcgcatca ttgatcccat cacccaccat gattactttt ttcccttggt caaggtattt
      421 ctggacaaca gcttctttat catctggtaa taaaccgcca taatattctt cgatccctaa
      481 ataatctgct actgcttggg cagcgttttt attgtcacca gtaagcatga caggagtgat
      541 ttttctttct ttcaatgttc ggataaattc ttttgcttct gtttttacta cgtcacctaa
      601 agcaacgatt gcagctagat gattttctaa aatcaggaag ctgatggtat ttccttgttc
      661 ttggtaaggt ttcaataatg cttgttctac gtttaatccg agacgctcaa cttctttttc
      721 attaactatt ttcacttgtt gttttttgac tgttgcctct agcccgactc ctgaaagatt
      781 ttttagattt tcagcttgat aaggcttgat ttcatgttct ttcaaataat tcataatgcc
      841 aacagccaat ggatgattgg cattcgcttc caaggctcct agatattgaa ggatttcatt
      901 tttattgaac gcatcatcaa gtacttcgac acccgttaca gtaaattttc cttctgttag
      961 tgttcctgtt ttgtccagca tgatcacatc tagatcattg gcttgctcca gtgcattgcg
     1021 gtttttcaaa agtaatccgt ttttagctgc tattgatgtg gaacgagcaa caactaatgg
     1081 gatagctaaa cctagagcat gaggacaggc gatgataaag actgttacca tacgttctaa
     1141 tgcattagga agatctgtca agaacaacca ggcgatgaat gccaggatac ccacaattaa
     1201 tgcgacataa aacagccatt ttgccacttt gtcagataat gactctagct tggatttttc
     1261 tccttgtgct tttcgcacca tttccataac cttcgctaga taaccatttt caccagttcc
     1321 agttacttcg atttcgatcg ttccatcccc attgatagaa ccgccaatca ctttgtcatt
     1381 ggcttgtttt ttgattcctc ttgattcgcc agtcacagct gattcgtcaa caattgtttc
     1441 acctttcaag attacaccat ctgttggcat tttatcacca gaccggacga tcaaacgatc
     1501 accttcgttt acttctttca atgaaactgt ctcttctttt ccatctttcg tcaagcgttt
     1561 cactgattct ggcagtaatt ctgctagttt ttgtaaagca ttgctggcat tcgacacagc
     1621 attcatttca atccagtgac ctagtagcat aataacgatc aaagtagcca attcccagaa
     1681 gaaatccatg acgtgtgtat gtggattgag cagatttgcg ataaacgaat agacactata
     1741 aatatatgca actgtaatcc ccatcgcgat cagtgtcatc atagcaggac ttttttgttt
     1801 caattccatc ttagctccac ttaaaaatgg ctgaccgcca tagataaata gtatagttgc
     1861 taagatcaat acgagccaat cagaaccagg aaacgttact tgaaatggaa attccattcc
     1921 catcattggt gaaaaaagaa tgattgggat agctaggata agcgatagcc aaaatttttg
     1981 tttgaaattc cccatgtgca tggaatgatc catgccgccg tgttcgtgat ccatgtgcat
     2041 cgaatggtcc atttgtttgc tgtttgctat atctccatgg ttatgtccca tgtgcatgga
     2101 atgatccatc tgactatggt catgtttcat ctccatctgt ttttcatgag attctgtact
     2161 ttctttgttt actacttctt ttttatgctc atgttttttc tccatatcgt tcccattcat
     2221 ttttactcca tcccttctct tactttttca tgtgtcgatt taagcacagg gagttcaaca
     2281 atacactgac ggaactaaac gccatcgctc ctcctgcaat gattggattc aaaaagccta
     2341 gtgcggcaaa aggaatacca atcgtattat agacaaaagc ccagaaaaga ttttgtttga
     2401 tttttctcaa tgtcaaccta gacaactcga ttgtttgtgc aatggatgcc aaactgctat
     2461 tcatcagcgt cacatcggct gtttccatcg caatgtccgt tccacttccc attgccatac
     2521 cgacatcagc taatgctaag gccggtgcat cattgattcc atcgcctgcc ataccgactt
     2581 ttttgccatc tttctgaagt ttttctacgt aggctgcttt atcctctgga agtacttcag
     2641 caaagatatg ctttggatca ataccaactt gtttaccaat cgtttcggct gccagtttgt
     2701 tgtctcctgt cagcataaaa acatctaatc ctttattctg gagctgcttg attgcttgtt
     2761 tgacttctag tttgatttga tcagccacgg caatcaaccc gatcacttgc ttttcatcag
     2821 ctaaaaacat gactgttttt ccctgctgtt ctaattctaa cgcgtgttct tggtattcat
     2881 caaatgatag gttcaattca attaatcgtt tacgtgtacc cgcaaaatag cgtactccgt
     2941 taatcgtacc gctgattcca gcacctgggt gggctgtaaa atcaatcata tcgtatgttg
     3001 ctgcttcttg cagttttccg tattccacga ttgctttacc tagtggatgt tcagaagctt
     3061 gttctaaagt ataaaaaata gataggactt ctttagaacc gactagatct gtaactttgg
     3121 gctttccttc tgtaatcgtt ccagttttat ccaaaacaat gctgtctaag tgagcagctg
     3181 cttctaatgc ttctccgcct ttaattaaaa ttccatttcg tgcaccaaca cccgttccta
     3241 ccataatagc tgttggagtc gctaaaccta atgcacatgg acacgcaatg actaatacag
     3301 agacactatg gatcaatgcg agttgccaat caccagtgat caaacctgta gctatgagcg
     3361 tgataaacgc gatgactaat acgatcggaa caaaaatccc tgagatccga tctgcgattt
     3421 tttggattgg ggctttgctc ccttgagcat cttccaccat ttgaatgatt tgcgctaata
     3481 ctgtctgctt gccgacttgt gtaacttcca tgtgaagtag accattcgta ttgattgtcc
     3541 cgccaaagag cgtgtcatcc ggattctttt ctacaggaag attttcacca gtaagcatac
     3601 tttcatctat cgcactgctt cctgaaataa ttcgaccatc tgctggaatc tgctcaccag
     3661 gacggatgac tagttgatca ccaacgacta cttcttcaat cgctaacgtt tcttctttcc
     3721 cgtttcttat cacttgggcg gtttttgttt gaagagacat caattgtttg attgcattac
     3781 ctgttttcgt ttttgctgta tgttccaaat atttgccgag caaaatcagc gtgatgatca
     3841 tactgctgct ttcaaaataa agatcttggg ggtgtccacg gaaaaatccg ttgtaaatgc
     3901 tcaatgcaaa ggcagccgat gttccaattg ctaccaatac atccatattt ggtgctttcg
     3961 tcttgattgc atggtacgca cctttataaa aacgagcacc gacataaaat tggacaggag
     4021 cagacagcac taactggacg attggaaaat gaaaaaagtg aacaatcgcc gcatggcttc
     4081 ctaacatcat agcaatcatt gacaacatca acggcaaagt caaaaccgta ctcaatataa
     4141 gatcgaatag catttttttc aaatacgctt gcttttcttc tgcaattttt tgtttgtggg
     4201 cttcatcgta caaaattgca ccatagccga tgttttctac gctttggatt aatttttcag
     4261 tggtcgtccc ttcatatttg acacttgctt tttcagtggc caagttgact gtggcattga
     4321 ccacaccagg ttgtccgttc agctcttttt cgatcctagc agaacaattt gcacaagtca
     4381 tacctgtaat gacgaacgta tccattttgg tttctgctgt tgccatcaaa tcacctctgc
     4441 tttataaccc aatccattga ttgcttgaca aatcttttcg gattgaactt ttgtttcatc
     4501 aaacttgacc gtaccgtttg cttttttcaa atttactttc actttttgca cgccgtcaag
     4561 tgcgcttact gtttcttcta ctcttgctgc acaatgattg cagctcatac cttcgattga
     4621 aaattgttgt ttcatttttt cttcctccta ttgatgttgt ttacattcac attgacctgg
     4681 gatacagtta cattcgatcg tatctactgg ttgcttttgt tccagttgtt tcaaaatctc
     4741 attgatatct tcttgagtca aagtggcttc ttctactaga tccgcaatcg tctctccaat
     4801 cctttttgca cagatatggg aaaaaagatt ttccgtcgca ctgcgaactg tttccatctc
     4861 cgagacagct ggataataaa tgaatttttt tccttcttgt tctgtccaga tcacttcttt
     4921 ttttaccaaa cgacccagca aagttttgat cgttgctggt ttccaatcca tcgaatcagc
     4981 taagatctgc gtgatttctt gggctgtcgt ctgtccaagt gtccaaataa cacgcatgat
     5041 ctcccactct gaatcactga tctttactgg cgttttgact ttttccattt atttcacacc
     5101 tttcgtttac aaatgtaatc attatcttat gaatacagat tacacttgta aacaaaaact
     5161 gtcaattatt tttgctctct attttcaatt tagttaaaaa ttcttgtttc tctcgtcttg
     5221 ttttaaggat gatcagttta tttcttgcat tagctacttg gatcagctgc tgtattttcg
     5281 gttcattgtt ttcttcaaaa tgccagataa aagataaaaa ttctaagtat tccctgttta
     5341 gtttctccga aaatgattca ggcatatctg gccgagattt tttgtttatc tttcttttta
     5401 gagaacgcca aactactcgg tagatggcga gataacgcgg cactttaagc caaatgatct
     5461 tatctgcttc tttaatcctt tcctctaatg tagaagtata atttccttca acgatccatg
     5521 acggattaga taccataaac aattgctgtt cttgcaaaaa ccactttttt gcctgaatac
     5581 tgtagtctgt tgtatgccat aaaaggtcta gcggcagtag cggaaagtcg gtgatttctt
     5641 tgatcttcct tgcgagggtc gattttcccg acccactttg tccaatcacg atgatcttca
     5701 ttcttctccc tcacttctct ttggaatttg gttcgatcat accacttata acgccgcaaa
     5761 aaaacaaggg actgtgacaa aagtcgtgtc aaagtccctt gtttcgaa
//
LOCUS       DADGKS010000132         5743 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.137, whole genome shotgun sequence.
ACCESSION   DADGKS010000132 DADGKS010000000
VERSION     DADGKS010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5743
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.137"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            237..1628
                     /locus_tag="JXV47_002805"
     CDS             237..1628
                     /locus_tag="JXV47_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAX1488801.1"
                     /translation="MNKNGEWNAARRIFIILMDVLVLNVSIYLSFLLKFQGEVPVRNL
                     ETFQHSAIFISIIFIALNILLGAYVFYNRMISDIVFITVIGQVLIALGIMVVTFAGRW
                     FAFPRGVILISFILGTILLSVYRIVVYKLYLRVSRDKKVLIVGLEKDVAPAIQNFQSK
                     KNNKHKVEAVAIDNYYENTKKLIDDMDIVYLASKIPEDEKINIYQLVTKKEKKLFLNT
                     TFENLTMINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLILLILASPFMLIT
                     AILVKTTSPGPIIYKQVRITKNQKEFSIYKFRSMSATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNEENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLLLDLKILLQTIKILFDKMSSQGLDEDENISS
                     LAEIDFSQEKIYR"
     gene            1687..2490
                     /locus_tag="JXV47_002806"
     CDS             1687..2490
                     /locus_tag="JXV47_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAX1488802.1"
                     /translation="MLLSLYDKEKPEYLKEALTSIFEQTVMPKEIVLVYDGPINEKLQ
                     VVVTYFQQKDPHLFTVVKLEKNQGLGIALAIGLEHTKNRLVARMDTDDIMEPQRLEKQ
                     LEIFQKDPEIAIVGSNIEEFTGTLSNVIGKRIVPEYNNAIRVFSKRRNPFNHMTVMFD
                     KKAILEVGNYQPLSGFEDYYLWARLLKAGYKGYNIQETLVYARTGKDMYARRGGMKYL
                     GSGLMGRYRIWKDGLGSVKDFIIVSCGHIFISLLPNQLRGKFYQTQLRK"
     gene            2523..3377
                     /locus_tag="JXV47_002807"
     CDS             2523..3377
                     /locus_tag="JXV47_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HAX1488803.1"
                     /translation="MKKIQQITLKMSQEIVDFCLKNQLLCYFCGGGAIGTVREQGFIP
                     WDDDLDFFMPREDYEKFYQLWVNSEKSKKYPIQKASKNYNDHNSFTTIRDADTTFIKT
                     YQRDLDIVHGITIDIFPLDVAPVSKFSRKIQKLWALVYALFCSQVVPEKHGGIMATGS
                     KILLSIFRSPRTRYKIWSFAEKQMTKYNNEPTGYVTELCVGPKYMGNVYPAKDFESAV
                     WVPFEDTEMPVPVGYDNYLSQVFGDYMQLPPEKDQVSHHEAVYIDPEHPYTMYKGKYY
                     LTKGAEKK"
     gene            3374..4075
                     /locus_tag="JXV47_002808"
     CDS             3374..4075
                     /locus_tag="JXV47_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HAX1488804.1"
                     /translation="MITAIIIAGGVGKRMGQDIPKQFITIEGKPIIIYTLESFQHHPQ
                     VDRILVVCKSGWEETMWAYIKEFNISKVKWVITGGSKGQESINNGVQFLKDYSEDDDT
                     IIIHDGIRPLVDELVLSDVIVKCKEFGNGVTSLPYNEQIFIKKTEETTEQYVDRNTLR
                     RVSTPQAYQYGKLRAAYDRAVKEDIGMTDSSYTNTMMVDLGETLYFAAGSDKNIKLTT
                     TDDLELFKAYLKMKD"
     gene            4083..5150
                     /locus_tag="JXV47_002809"
     CDS             4083..5150
                     /locus_tag="JXV47_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAX1488805.1"
                     /translation="MMTLIKQPMYQEDLAKVINHTPKIKQLHGKSVLMIGASGMIGSF
                     LIDTLMAANEQLGIKIKVYAMGRNRQKLEKRFASYLELDTFEIVEGDVTEPLPKEIQA
                     DYLIHGASNTHPKAYATDPIGTIMTNLAGTEQVLKHAVATQPVRVLFLSTVEIYGENR
                     GDIEKFTEDYCGYIDCNTLRAGYPEGKRVSESLCQAYIAKHDLDIVIPRLCRTFGPTM
                     LLSDTKASSQFILNAVEQKDIVLKSEGNQYFSYVYVGDAVSAILHLLLEGEKGEAYNV
                     SSENFDLRLKELAQQLADISGKQVIFELPDEIEQKGFSKASTAVLENKKIKETGWKPI
                     FPLNESLVHTVELVKGEKYNV"
     gene            5143..>5743
                     /locus_tag="JXV47_002810"
     CDS             5143..>5743
                     /locus_tag="JXV47_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAX1488806.1"
                     /translation="MCEISIIVPVYKVEKYLRKCVDSILAQTFTDFEVILVDDGSPDN
                     SGKICDEYAEKDNRVRVIHKENGGLSSARNAGIDVARGKYLGFVDSDDYIDEDMYEIL
                     YENLKIHDADISSVELIPFYGDRYKKANKEKKVIILNKKEAIKSVLEGTQFYAYAWNK
                     LYRKELFKDNRYLDGKTFEDAYIIIDLLFQTEKIVVSNEE"
BASE COUNT         2032 a          847 c         1114 g         1750 t
ORIGIN      
        1 atatgaatat tgtaacttgt gaataaggaa ttagcaggag aatactagtt cagcataaag
       61 gaagtgatgg gacttctgag acaactttct gttatgcaga aatacacata taaacagaca
      121 ataaacgctt ttccccgttt cttttaattt cctttacaat ttggttattc actaggtttt
      181 taaactttgc tatggtaaga tgatagaggc attattttat ggttaggagt gtatatatga
      241 ataaaaatgg ggagtggaat gcggcacgca gaatattcat tattcttatg gatgtacttg
      301 tattaaatgt atcgatctat cttagttttt tgctgaaatt ccagggagaa gtaccagtga
      361 gaaacttaga aacctttcag cattcagcaa tttttatttc catcatcttt attgcgttga
      421 atattttgtt aggagcttat gtattctata accgaatgat cagtgatatt gtcttcatta
      481 ctgttattgg acaagtacta atagcattgg ggatcatggt agttactttt gctggccgat
      541 ggtttgcatt tccgcgtggc gtcattttga tctcgtttat cctaggtacg atattactta
      601 gtgtttaccg gatagtcgtt tacaaactgt acttaagagt cagtcgtgat aagaaagtcc
      661 ttatcgtggg tttggagaaa gatgtcgcac cagctatcca aaattttcaa tctaagaaaa
      721 acaataaaca taaggttgaa gcagtggcaa tcgataatta ttacgaaaat acaaaaaaat
      781 tgatcgatga tatggatatc gtctatttgg cttctaaaat cccagaagat gaaaaaatca
      841 acatttatca attagtgact aaaaaagaga agaaattatt tttaaatacg acttttgaga
      901 atctgacaat gataaatccg aatattatga attttgaaga tgaaagcatc attgaagctt
      961 ctgggttcag aatccaacca gaatacgaac tattcaagcg tctctttgat atcatcgttt
     1021 cgcttatttt actgatcctc gcctcacctt ttatgctaat cacagcgatt ttggtaaaaa
     1081 caacttcacc tggaccaatc atctataaac aagtacgtat tacgaaaaat caaaaggaat
     1141 tttcaatcta taaattccgt tccatgagtg cgacagctga agcaaaatca ggaccagtct
     1201 tggctaaaag taacgatgca cgtgtgacac cagtaggtaa atttatccgt gctgtacgtt
     1261 ttgacgaatt acctcaaatc tttaatgtat tgaaaggcga tatgtcgatt gtcggtccaa
     1321 ggccagaaag accatttttc gttgatcagt tcaatgaaga aaatccttat tattacttaa
     1381 gacacaatgt acgtgcggga attaccggat atgcacaagt atacggaaaa tatgtatcag
     1441 attataacag taaactacgt tttgatttgt tgtatatcaa aaaatattca ttactattag
     1501 atttgaagat tttacttcaa acaatcaaaa tcttatttga taagatgtca tctcaaggac
     1561 tagatgaaga tgaaaatatt agttcattag cagaaatcga cttttcacaa gagaaaattt
     1621 atcgctagat tggaaaaatt ttgagcaaag aggtaggaga gaacattgga aaataaaaat
     1681 gtaagtatgc tgctttcttt atatgataaa gaaaagccag agtatttaaa ggaagcatta
     1741 actagtattt ttgagcaaac agtaatgcca aaagaaattg tattagttta tgacggccct
     1801 ataaatgaaa aacttcaagt agttgtcact tatttccaac aaaaagatcc tcacttgttt
     1861 acagttgtaa aattagaaaa aaatcaagga ttggggattg ctttagcaat tggattagaa
     1921 catacgaaaa atcgcttagt agccagaatg gatacagatg atataatgga accccaacga
     1981 ttagaaaaac aattagagat cttccaaaaa gatccagaaa tagcgattgt tgggagtaat
     2041 attgaggaat ttactggcac gcttagcaat gttatcggaa aaagaattgt acctgaatat
     2101 aacaatgcaa ttcgtgtatt ttctaaaaga agaaatccct ttaatcatat gaccgttatg
     2161 tttgataaaa aagctatttt ggaagtggga aattaccaac cattaagtgg gtttgaagat
     2221 tattatcttt gggcaagatt attaaaggca ggttataaag gatataatat tcaagaaaca
     2281 ttagtctatg cgcgaactgg caaagatatg tatgcaagaa gaggcggaat gaaatatctt
     2341 ggttctggtc ttatgggtcg ttatcgtatc tggaaagacg gtttagggtc agtaaaagat
     2401 tttataattg tttcttgcgg acatattttt attagcttac taccaaatca attaagagga
     2461 aaattttatc aaacgcaatt aagaaaatag gaggtttttc tttgtatagc actgatccaa
     2521 aaatgaaaaa aatacaacag attacgttga aaatgtctca agagattgtt gatttttgtc
     2581 taaaaaatca acttctttgt tatttctgcg gtggtggtgc catcggtact gtgagagaac
     2641 aagggtttat tccatgggat gatgatttag atttctttat gcctagagag gattatgaaa
     2701 aattttatca actatgggtt aattcagaaa aaagtaaaaa atatcccata cagaaggctt
     2761 ctaaaaatta taatgatcat aattctttta caactatccg cgatgcagat actacattta
     2821 ttaaaactta tcaaagagat ttagatatag tccatggaat tactattgat attttcccgt
     2881 tagatgttgc ccctgtttcg aaatttagcc gtaaaattca aaaactatgg gctttagtat
     2941 atgctttatt ttgttctcaa gtcgtccctg aaaaacatgg tggaataatg gctacaggta
     3001 gtaagatact cttatctatt ttccgctcac ctcgtacgag atataagata tggtcttttg
     3061 ctgaaaaaca aatgacaaaa tataataatg aaccaacggg ctatgtgact gaactttgtg
     3121 tcggacctaa atacatggga aatgtttatc ctgcaaaaga ctttgaatct gctgtgtggg
     3181 tgccattcga agatacagag atgccagtac cagttggtta tgataattat ttaagtcaag
     3241 tttttggtga ctatatgcag cttccgcctg aaaaagatca ggtttctcat catgaagcag
     3301 tttatattga tccagaacat ccatacacaa tgtacaaagg aaaatattat ttaactaaag
     3361 gagcagaaaa aaaatgatta cagctattat tattgctggt ggtgtgggta aacgaatggg
     3421 acaagatatc ccaaaacagt tcattacaat tgaaggaaaa cctattatta tctatacttt
     3481 agaatcattt caacaccatc ctcaagttga ccggatttta gtcgtttgca aatctggttg
     3541 ggaagaaacg atgtgggcgt atatcaaaga attcaatatt agcaaagtca aatgggtcat
     3601 tacaggtgga tcaaagggac aagagtcgat caataatggt gttcagtttt tgaaagacta
     3661 ttctgaagat gatgatacga tcatcatcca tgatggaatc cgtccactag tagacgaact
     3721 ggtattgtca gatgtaatcg ttaaatgtaa agaatttggt aacggtgtaa cctctctacc
     3781 ttacaacgaa caaattttta tcaagaaaac agaagaaacg acggaacagt atgtcgatcg
     3841 taacacattg aggcgtgtct caactccaca agcttatcaa tacggaaaac tacgggcagc
     3901 atatgaccgg gcagtgaaag aagacatcgg tatgactgat tcttcttata cgaataccat
     3961 gatggtagat ttgggagaaa ctttatattt tgctgctggt tctgataaaa atatcaaatt
     4021 gacaacaaca gatgatctag aattgttcaa agcatattta aaaatgaaag actaggtgaa
     4081 agatgatgac gttgattaaa caaccaatgt accaagaaga tttggcaaaa gtaatcaatc
     4141 atacaccaaa aataaaacag ctacatggaa aatccgttct gatgattggt gcttctggaa
     4201 tgatcggctc ttttttgatt gatacgttga tggctgctaa tgaacaacta ggcatcaaaa
     4261 tcaaagttta tgcaatgggc agaaaccgtc agaagcttga aaaaaggttt gccagttatc
     4321 ttgaattaga tactttcgaa attgttgaag gtgacgtcac agaaccctta ccaaaagaaa
     4381 ttcaagctga ctatttgata cacggtgcaa gtaacacaca tcctaaggct tacgcaactg
     4441 atccaatcgg tacgatcatg actaatcttg caggtacaga gcaagtattg aaacatgcag
     4501 tagcaaccca accggttaga gtattatttt tatcaacagt agaaatctat ggcgaaaatc
     4561 gaggcgatat agaaaaattc acagaagatt actgtggata catcgattgt aatacactga
     4621 gagcaggcta ccctgaagga aaaagagtca gtgaatcatt atgccaagcc tacatcgcaa
     4681 aacacgacct cgacatcgtg attccaaggc tttgccgtac gtttggtccg acgatgcttt
     4741 tatctgatac gaaagcatcc tcacaattta ttttaaatgc agtcgaacaa aaagatattg
     4801 ttttaaaaag tgaaggaaac caatattttt cgtatgtata tgttggagat gctgtttctg
     4861 ctattcttca tttactgctt gaaggagaaa aaggagaggc gtacaacgtt tcttcagaaa
     4921 actttgattt acgactaaaa gaattagccc aacagctagc tgatatcagc ggcaaacaag
     4981 taatttttga attgccggat gagattgaac aaaaaggttt ctcaaaagct agcacagcag
     5041 tacttgaaaa taaaaaaatt aaagagacag gttggaaacc aatttttcct ttgaacgaat
     5101 cattggttca tacagtagaa ttagttaaag gtgagaaata taatgtgtga gattagtatt
     5161 attgttcctg tgtataaagt tgaaaaatat ttaagaaaat gtgtagattc gattttagcc
     5221 caaacattta ctgattttga agttatatta gtagatgatg gatctcctga caatagcggg
     5281 aaaatctgtg atgagtatgc tgaaaaagat aatcgagtac gtgtgatcca taaagaaaac
     5341 ggcggattaa gcagtgctag aaatgcgggg attgatgttg cgagaggcaa atacttaggc
     5401 tttgttgaca gtgatgatta tattgatgaa gatatgtatg aaattttgta tgagaatttg
     5461 aaaattcatg atgccgacat tagctctgtt gaattgattc ctttttatgg tgatagatat
     5521 aagaaagcta ataaagaaaa gaaagtaatt atattaaata aaaaggaagc aataaaatct
     5581 gttttagaag gaacgcaatt ttatgcatac gcatggaata aactttatcg taaggaactt
     5641 tttaaagata atcgttactt ggatggaaaa acatttgagg atgcatatat aataatagat
     5701 ctattatttc aaacagaaaa aattgttgtt tccaatgaag aga
//
LOCUS       DADGKS010000133         5679 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.138, whole genome shotgun sequence.
ACCESSION   DADGKS010000133 DADGKS010000000
VERSION     DADGKS010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5679
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.138"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            8..81
                     /locus_tag="JXV47_002811"
     tRNA            8..81
                     /locus_tag="JXV47_002811"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:42..44,aa:Pro,seq:tgg)
     gene            101..173
                     /locus_tag="JXV47_002812"
     tRNA            101..173
                     /locus_tag="JXV47_002812"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:134..136,aa:Ala,seq:tgc)
     gene            201..274
                     /locus_tag="JXV47_002813"
     tRNA            201..274
                     /locus_tag="JXV47_002813"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:235..237,aa:Met,seq:cat)
     gene            288..361
                     /locus_tag="JXV47_002814"
     tRNA            288..361
                     /locus_tag="JXV47_002814"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:322..324,aa:Ile,seq:cat)
     gene            385..474
                     /locus_tag="JXV47_002815"
     tRNA            385..474
                     /locus_tag="JXV47_002815"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:421..423,aa:Ser,seq:tga)
     gene            487..560
                     /locus_tag="JXV47_002816"
     tRNA            487..560
                     /locus_tag="JXV47_002816"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:521..523,aa:Met,seq:cat)
     gene            579..654
                     /locus_tag="JXV47_002817"
     tRNA            579..654
                     /locus_tag="JXV47_002817"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:612..614,aa:Asp,seq:gtc)
     gene            656..726
                     /locus_tag="JXV47_002818"
     tRNA            656..726
                     /locus_tag="JXV47_002818"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:688..690,aa:Gly,seq:tcc)
     gene            740..813
                     /locus_tag="JXV47_002819"
     tRNA            740..813
                     /locus_tag="JXV47_002819"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:774..776,aa:Ile,seq:gat)
     gene            838..925
                     /locus_tag="JXV47_002820"
     tRNA            838..925
                     /locus_tag="JXV47_002820"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:872..874,aa:Ser,seq:gct)
     gene            947..1018
                     /locus_tag="JXV47_002821"
     tRNA            947..1018
                     /locus_tag="JXV47_002821"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:980..982,aa:Glu,seq:ttc)
     gene            1041..1130
                     /locus_tag="JXV47_002822"
     tRNA            1041..1130
                     /locus_tag="JXV47_002822"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1077..1079,aa:Ser,seq:tga)
     gene            1143..1216
                     /locus_tag="JXV47_002823"
     tRNA            1143..1216
                     /locus_tag="JXV47_002823"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1177..1179,aa:Met,seq:cat)
     gene            1235..1307
                     /locus_tag="JXV47_002824"
     tRNA            1235..1307
                     /locus_tag="JXV47_002824"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1268..1270,aa:Asp,seq:gtc)
     gene            1311..1383
                     /locus_tag="JXV47_002825"
     tRNA            1311..1383
                     /locus_tag="JXV47_002825"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1344..1346,aa:Phe,seq:gaa)
     gene            1388..1458
                     /locus_tag="JXV47_002826"
     tRNA            1388..1458
                     /locus_tag="JXV47_002826"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1420..1422,aa:Gly,seq:tcc)
     gene            1471..1544
                     /locus_tag="JXV47_002827"
     tRNA            1471..1544
                     /locus_tag="JXV47_002827"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1505..1507,aa:Ile,seq:gat)
     gene            1556..1627
                     /locus_tag="JXV47_002828"
     tRNA            1556..1627
                     /locus_tag="JXV47_002828"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1589..1591,aa:Glu,seq:ttc)
     gene            2104..2418
                     /locus_tag="JXV47_002829"
     CDS             2104..2418
                     /locus_tag="JXV47_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAX1488807.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            2434..2820
                     /locus_tag="JXV47_002830"
     CDS             2434..2820
                     /locus_tag="JXV47_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAX1488808.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            2849..4234
                     /locus_tag="JXV47_002831"
     CDS             2849..4234
                     /locus_tag="JXV47_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAX1488809.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            4237..4389
                     /locus_tag="JXV47_002832"
     CDS             4237..4389
                     /locus_tag="JXV47_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAX1488810.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            4412..5617
                     /locus_tag="JXV47_002833"
     CDS             4412..5617
                     /locus_tag="JXV47_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAX1488811.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
BASE COUNT         1688 a         1115 c         1308 g         1568 t
ORIGIN      
        1 aattaaacgg gaagtagctc agcttggtag agcacttggt ttgggaccaa ggggtcgcag
       61 gttcgaatcc tgtcttcccg ataattataa atttaaacac ggggccttag ctcagctggg
      121 agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct ccatttcatt
      181 taaataatga atatcttttt cgcggtgtag ctcagctggc tagagcgtcc ggttcatacc
      241 cgggaggtcg ggggttcgat cccctccgcc gcgattttta agagcctgga cctttagctc
      301 agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc tacaaggtcc
      361 attgtggcgt tgtaagtttc atatggagga ttacccaagt ccggctgaag ggaacggtct
      421 tgaaaaccgt caggcgggta aaaccgtgca agggttcgaa tcccttatcc tcctttttca
      481 tattatcgcg ggatggagca gtctggtagc tcgtcgggct cataacccga aggtcgtagg
      541 ttcaaatcct gctcccgcaa ttaaaaacta aaaacactgg ttccgtggtg taggggttaa
      601 catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc gccatgcggg
      661 tgtagtttag tggtaaaacc acagccttcc aagctgttgt cgcgagttcg attctcgtca
      721 cccgctttta gttttttatg ggcctatagc tcagctggtt agagcgcacg cctgataagc
      781 gtgaggtcga tggttcgagt ccatttaggc ccattagtac aaaatcttat tggttttggg
      841 gaagtactca agtggctgaa gaggcgcccc tgctaagggt gtaggtcggg aaaccggcgc
      901 gagggttcaa atccctcctt ctccgtttca atattttgtt ttacctggcc cgttggtcaa
      961 gcggttaaga caccgccctt tcacggcggt aacacgggtt cgaatcccgt acgggtcatt
     1021 aatttaatat agttttacat ggaggattac ccaagtccgg ctgaagggaa cggtcttgaa
     1081 aaccgtcagg cgggtaaaac cgtgcaaggg ttcgaatccc ttatcctcct ttttcatatt
     1141 atcgcgggat ggagcagtct ggtagctcgt cgggctcata acccgaaggt cgtaggttca
     1201 aatcctgctc ccgcaattaa aaactaaaaa cattggttcc gtggtgtagg ggttaacatg
     1261 cctgcctgtc acgcaggaga tcgcgggttc gattcccgtc ggaaccgttt ggctcggtag
     1321 ctcagttggt agagcaatgg attgaagctc catgtgtcgg cagttcgatt ctgtcccgcg
     1381 ccattatgcg ggtgtagttt agtggtaaaa ccacagcctt ccaagctgtt gtcgcgagtt
     1441 cgattctcgt cacccgcttt tagtttttat gggcctatag ctcagctggt tagagcgcac
     1501 gcctgataag cgtgaggtcg atggttcgag tccatttagg cccatttatt ttattggccc
     1561 gttggtcaag cggttaagac accgcccttt cacggcggta acacgggttc gaatcccgta
     1621 cgggtcatgg aagatacttt ttgagtatct ttttcttttt atctgaaaga atgattttaa
     1681 aaagcttagc agagttatct ttatggatga ttgtgctaag cttttttgga cagttctaat
     1741 gtaaaatatt tttatatttt ttaagcaaaa aatagcataa aaatctagtt atccgcataa
     1801 aaactggact tatcacactt tatcaaggtc aaaaccactc aatttactac taatttacta
     1861 cttatgaatg agctttgata cgacgattta tccttgaaaa gtgaagatat aaagatactt
     1921 ccaataaaat ttgaatattt aataggtaga cacttcaaaa aatgaggtgt ctattttttt
     1981 acccgatttt gaaaggaagt gaacttatga aaacaaaaaa tcaagaatca aaaggtcgtt
     2041 ccccactctt taagaccatc aaacattcat tcagccaata aaaaagaaag gataggtaaa
     2101 aatatggaac ttaaatttgt gattcccaac atggaaaaaa cattcggcaa tttagaattt
     2161 gctggcgagg ataaagtcgt tcagcgaaga atcaacggac ggctaactgt cttatcaaga
     2221 agctataatc tctattctga tgttcaaaga gcagatgata ttgtggtggt gcttcctgct
     2281 gaagctggcg aaaaacattt cggctttgag gaacgtgtga agttagtcaa tccacgtatt
     2341 accgcagagg gctacaaaat cggcactcgt ggttttacaa attacctttt acatgctgac
     2401 gacatgataa aagaataaag aaagagagga aaaatgatga gattagcaaa tggcattgta
     2461 ttagataaag acacgacttt tggagaattg aaattctctg ctctacgtcg tgaagtgaga
     2521 atccaaaatg aagacgggtc ggtttcagat gaaatcaagg aacgtaccta tgacttaaaa
     2581 tccaaaggac aaggacgcat gattcaagta agtattcctg ccagcgtgcc tttgaaagag
     2641 tttgattata acgcacgggt ggaacttatc aatcccattg cggacaccgt tgctactgcc
     2701 acctatcaag gagcagatgt tgactggtat atcaaggcag acgatattgt gctgacaaag
     2761 gattctagtt cattcaaagc tcaaccacaa gcaaagaaag aaccgacaca agacaaatag
     2821 tcgctaggta gaaaggagac tttttcgcat gaaacagcgt ggtaaaagga ttcgcccatc
     2881 tggtaaagat ttagtctttc attttacgat agcgtcactc ctgcctgttt tcctgctggt
     2941 tgtcggactg tttcatgtga agacaatcca gcagatcaac tggcaggatt ttaacctatc
     3001 acaagcagat aagattgaca ttccctattt aattatcagt ttcagtgtcg caattcttat
     3061 ctgcttgctg gtagcgtttg tattcaaacg ggttcgctat gatacggtta aacaacttta
     3121 ccaccgtcaa aaactggcaa agatgatact tgaaaacaag tggtatgaat ctgaacaggt
     3181 caaaacagag ggtttcttta aagatagtgc tggtcgtaca aaggaaaaga taacctactt
     3241 ccctaaaatg tattatcgac ttaaaaatgg cttgatacag atacgggtgg aaatcacgct
     3301 gggaaaatat caagaccaac tcttacactt ggaaaagaaa ttagagagtg gcttgtactg
     3361 tgagctgacg gataaagagt taaaggattc ctatgtggaa tatactttgc tctatgacac
     3421 catagccagt cgtatttcta ttgatgaagt agaagctaaa gatggtaaac ttcgcttaat
     3481 gaaaaacgta tggtgggaat atgataagct ccctcatatg ttgattgctg gtggtacagg
     3541 tggcggtaaa acttacttta tactgacact gattgaagcc ttgcttcata cagattcaaa
     3601 actgtatatt cttgacccga aaaatgctga ccttgcggac ttaggttctg tgatggcaaa
     3661 tgtctactat agaaaagaag acttgctttc ttgcattgaa acattctatg aagaaatgat
     3721 gaaacgtagt gaggaaatga agcagatgaa gaactataag actggcaaaa attatgctta
     3781 cttaggtctc ccggcacact tcttaatctt tgatgaatac gtcgctttca tggaaatgct
     3841 gggaacaaaa gaaaacaccg cagttatgaa taagctgaaa cagattgtca tgttaggtcg
     3901 tcaagctggc ttctttctaa tactggcttg tcaacgtcca gacgcaaaat atttaggcga
     3961 cggaatccgt gatcagttta atttcagagt ggctttaggt cgtatgtctg aaatgggcta
     4021 tggcatgatg tttggcagtg acgtacaaaa ggatttcttc ttaaagcgaa tcaaaggtcg
     4081 tggctatgtt gatgtaggaa caagtgtcat atcagagttt tatactcccc ttgtaccaaa
     4141 aggatatgat ttcttggagg aaattaaaaa gttatccaac agcagacagt ccacgcaggc
     4201 gacgtgcgaa gcggaagtcg caggtgtgga ctgatcttgc tggctggtgt ggcaatagcc
     4261 acgccagcac ttaacccccc gtatctaaca ggggggtaca aatcgacagg aaacagtcaa
     4321 aaaaacatta gaaaatcctt tggttacaag ggatttacaa aatttcagcg tatgtcaaat
     4381 gggctttaaa agttgacata cgcctttttg attggaggga tttttactga atgaacaaac
     4441 ttggttacag catttaaaag aaaaacgctt ggcttatgga ctatctcaaa accgtttagc
     4501 tgttgcgact ggtattacaa ggcagtatct aagcgatatt gaaacaggaa aagtcaagcc
     4561 atcagaggat ttacagcagt ccctttggga agctctggaa cgcttcaatc ccgacgctcc
     4621 ccttgaaatg ctgtttgatt atgtaaggat tcgctttccg acaacagacg tacagcaggt
     4681 ggtcgaaaac atcttacaac tgaaactgtc ctattttctt catgaggact atggtttcta
     4741 ttcttattca gagcattatg ctttaggcga catattcgtc ctttgctccc atgaactgga
     4801 caaaggagtt ctggtggaat tgaaaggtcg tgggtgcaga caatttgaaa gctatcttct
     4861 ggcacaacaa agaagctggt atgagttctt tatggacgtt ttggtggctg gcggtgtgat
     4921 gaaacgcctt gaccttgcca ttaacgataa gacagggatt ttgaatatcc ctgtactcac
     4981 tgaaaagtgc caacaggaag aatgtatctc cgtcttccgc agttttaaaa gctatcgcag
     5041 tggcgaactg gtacgcaaag aggaaaagga atgtatggga aacaccctct atatcggttc
     5101 attacaaagt gaagtttatt tctgtatcta tgaaaaggac tacgagcagt acaagaaaaa
     5161 tgatattccc attgaagacg cagaagtaaa aaaccgtttt gagattcgat tgaaaaatga
     5221 gcgtgcctat tatgcagtcc gtgatttact cgtctatgac aatccagagc ataccgcctt
     5281 taaaattatc aatcggtata tccgttttgt agataaagac gattccaaac ctcgttctga
     5341 ttggaaactg aatgaagaat gggcttggtt tattgggaac aatcgtgaac gattaaaact
     5401 aaccacaaaa ccagagcctt actccttcca aaggacgctg aactggctat ctcatcaagt
     5461 tgccccgacc ttaaaggttg cgattaaact tgatgaaatc aaccagacgc aggttgtaaa
     5521 agacattctc gaccatgcga aactgacaga ccgacacaag cagattttga agcaacagtc
     5581 agtaaaagaa caggacgtga taacaacaaa aaaataactc aaatacaaat tcattgaata
     5641 tagagaggag aacattttta tgaattttgg acaaaacct
//
LOCUS       DADGKS010000134         5644 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.139, whole genome shotgun sequence.
ACCESSION   DADGKS010000134 DADGKS010000000
VERSION     DADGKS010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5644
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.139"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(1014..1304)
                     /locus_tag="JXV47_002834"
     CDS             complement(1014..1304)
                     /locus_tag="JXV47_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488812.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            1646..1942
                     /locus_tag="JXV47_002835"
     CDS             1646..1942
                     /locus_tag="JXV47_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488813.1"
                     /translation="MQIGVLKWLQFTKQKGVHFPMQFLEPKNKNAKSVDWEISEQVRV
                     IVKQYAEYAERTESEAVDEFLLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            1949..3901
                     /locus_tag="JXV47_002836"
     CDS             1949..3901
                     /locus_tag="JXV47_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HAX1488814.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="JXV47_002837"
     CDS             complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="JXV47_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HAX1488815.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(4797..5489)
                     /locus_tag="JXV47_002838"
     CDS             complement(4797..5489)
                     /locus_tag="JXV47_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAX1488816.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT         1839 a          981 c          903 g         1921 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattta agtagttcag ttttggagta caaaaagtga
     1501 aaatgtaaac ctaaatgagt atcaaattgc aactgaattt gatactcgtt ttttattgtt
     1561 aaatcaacgt ttgttgttaa tttacaccac aaaatgtaag ttaaaatgta tataaaaatg
     1621 cgaacgtgaa ataattattg taggaatgca aattggtgtg ttaaaatggt tacaatttac
     1681 taagcaaaaa ggggtgcatt ttcctatgca atttcttgag ccaaaaaata agaacgctaa
     1741 gtctgtggat tgggaaatat cagagcaagt aagggtgata gttaagcaat acgctgaata
     1801 tgcagagcgt actgaaagcg aagcagtgga tgaattctta ttgaacattt tagacgataa
     1861 gaagtttatt gaatggattg ccaacaagcg aagtaataag cggattgttg aaaaaatggg
     1921 tatcaaagat agagtgggtt gatagacaat gaccaagctt aaaagattag ccacgaagga
     1981 agatgaaatt gtagatgtta aaattccgat ttcaaacgaa gaattaaaag atagggctaa
     2041 acaatatgat ttattaactc caaaacgatt tgcaacaagg tataacaaaa tgttgttctt
     2101 gccaacgtct tttaaatgga acggttctga atatcccatt caatataatt actgcatcaa
     2161 tccgttttgt tgtaattttg ggaaagaaca gcacaaattc aaagatgtaa aagggaaacc
     2221 aagtcgatat aaaatgactg gtagttccaa agataaaggt cataaaggta tgtactgcaa
     2281 tgacaatcct attggcagag gtgtatcgca aaactgtaca gtaacccctt tatctaattg
     2341 gtctgttgtt gaagaaatta aacgccttat agaaatcaat agcatccaag atgttgagcc
     2401 agattatcaa tttcataaag aaggctgctc ggaagaagaa tcaaccccat tcaatgagcc
     2461 gaagcaattt tacaaaaggg ggaaaagtag gggcaaatct caacgctatc aatgtaaggc
     2521 gtgtaagaag ttcactaatg ttctaccaaa aagagaagaa accactactt atcaccaaca
     2581 aaagaacacc attcttccaa tgttcgctaa gatggttgtt ggaagggttt cagtcagtcg
     2641 tacttgtgat attttaggaa ttggagttgg aacctactat cataagctgg agtggctgta
     2701 taggcgttgt ttggagtttt tagaacgata tgagacacaa ccccttcaaa caaagaaatt
     2761 taacgagatg tggcttaata cggacaagat gcactactac ctaaataacg tccgtaagaa
     2821 aggacaaggt tcaaagaaat atacggggtt tgaagacctt aatatgcaaa cgtatatagt
     2881 tgtatctgct gaggtcttat caagatatgt gttccgttct gatgttgcct atgattggaa
     2941 tatttcaatg gatgaattaa atgaagatac aagaaaattc aaagaagacc atctcaatac
     3001 ttttagtcgt aaaaatgata ggttagattg gtcttattat ccacaagaac catccgctaa
     3061 cgatagcgaa aataggaatg cttatcttca cgaattaggg aaaattacta ataggagtag
     3121 atttgtcgat ggtttaaatg ttgatgctcc ttatactaca actgctcact attggttaat
     3181 taaacaaatg gttaatgccg acgaatggcg aatgattagt gatgatgact tctctattag
     3241 aaacgccttt tatagagtat tcacgaaaga attaaggttg agcgatgcac atcattttat
     3301 ttgccaagtt aacaagacga aaagcagaaa acaatgctta aaagaattcg gacaagcaaa
     3361 agcagaactg ctcgattggg gagatatcag aggattcaaa acaaagtttc tacggacttt
     3421 ggcatctcat tatctaactg aattactaac aagtcatcaa ttccacgaag aggctattag
     3481 taaagatgga gaaagatatc gcaaatatgc cgataaccct atcaaacatc cattagccac
     3541 taaggataaa ggattttatt cagttgattg tagaacggat ttatctgctc tggaaccaaa
     3601 cgaaatcgca aagatgctat taaatgttaa tgaccattcg accaatagct ttattcaaca
     3661 gataagacgt tatatatcat ctcttgaaag accattaaca acagctcgtg gtgataagaa
     3721 gagctatatt tacgctaact tcaatccgaa gtatgctcaa tttgcgatta caattctaag
     3781 aacttactac aacttttgtc gcccttttaa atcagcggat aaaaaggttt tgacacctgc
     3841 tcaaagatta gggattacag ataaacaatt tgattggaaa gatataattt atttcaaatg
     3901 acaaaaagag cttggagtaa tcccaagctc ttgtgcttta tctttactgt tcttcttcaa
     3961 ttaacgcacc cgttaactca ataagttttt tctttcatat acatgaaaat agtagttata
     4021 cggattttta tcattcttta tccctttttg ggcaaatacc tcattccatt cctcataatt
     4081 cacttctgga aaaaaagtat ctccttcgaa ttcatgatgt atttttgtga tgtacatttt
     4141 ctcaacataa gggaaaaaca aattataaat ctgttctcct ccgaaaataa aaatttcttc
     4201 ttcgttttta cataactcaa aaacatcttc tattgaatga acaatttcac aaccattaaa
     4261 ggtaaacccc ttatctctcg tcagaataat atttcttctg tcaggtaagg ctcttccgat
     4321 tgattcaagg ttcttcctac ctaatattat cggatgtccc tttgtagtat ttttaacata
     4381 ttcccagtcc ttgggaatcc tccaaggaat gtcattctct ttgccaatca ctctattctt
     4441 atccatcgca gcaatcaaag aaactttcat ttataacaca gcctttttaa ctaatttacc
     4501 atctaatttc ttatttctat caaaaaacct tttctcatta tcctgcccgt tagttgaata
     4561 agcaattttt tctataagtt atattatcat aataccacaa aatcacaaat tttcattcaa
     4621 ttatcatttt caattgcatt ttataaatca ttttgtatgt aatttggtat gtaagttaaa
     4681 atgaaaaaag tagtccattt tgaagtacat tttgtcattt tgtactccaa aactgaacta
     4741 cttagtatag attactgttg cttctttact aatttaggtt tacttgttaa gaaagattat
     4801 ttacgcaaat gttcttcaac aatttgctga gatttatcag ctgtatcttc cacttcatct
     4861 tttgcttttt ctaacttttg aatatattgt ttcaagcttg agttttcagc agttgcttcg
     4921 tctaatttct tttgtgtatc tgttaactga gtttctacat ttgttttttc ttgtgtcagt
     4981 gttgcgattt gttgattcaa accatttaca gtattttgta attctgaaag ttttgcttgt
     5041 gcttcttgta gtcttgctgt ccaatctgca ttcagatgat tgatttcatc atttttttgg
     5101 ttgatctcat ctagtttgac attgatttca ttttgtttgc tttgtagttg tgcatccttg
     5161 ctgactaatt gactttctaa gttttgtttt tctgctgccg attgattttt ttggttttct
     5221 aattcattta cttttgtttg gtattcttgg acatctgcct ttgaatcttg caatgtctgt
     5281 tctttttgtg ctagtcgagc ggtaagatct gtaatcgctt gctctttatc tgtcaatgta
     5341 tgatcaagct gtgtcagatt ctcattgatt gtatcaatat ctgtctctcc accccacaaa
     5401 ataatttcat ttgcgtaccg cgtgcctgtg tagccaatta gacatagaaa tgcaacgaca
     5461 atcccaccag taataaattt ctttttcatt tgcatagctc cttaatccaa tacttttaca
     5521 tgctaaaagt aagtgatctc aaacacaatg tcaagcgttt ttaaattaca tatgtaattt
     5581 taatataaat actatcaaat actcatttaa tcctcctttt ttatctattt aaaaaatctt
     5641 tttt
//
LOCUS       DADGKS010000135         5531 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.140, whole genome shotgun sequence.
ACCESSION   DADGKS010000135 DADGKS010000000
VERSION     DADGKS010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5531
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.140"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..855
                     /locus_tag="JXV47_002839"
     CDS             <1..855
                     /locus_tag="JXV47_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HAX1488817.1"
                     /translation="LYFFPSIRSLDVWSGKDLLQSEFIKSARQQLANYQLIVFLDYGF
                     DMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEIYHFDFLEAKELGLK
                     HNSSFYSKHMDFSSSEPKTDLFFGATNNGRKERAEKYKQEFTKRGVTTNYFILPLRGN
                     EQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQKKLVTDNQAIAHYQF
                     YHSENIFLLQERDLDELPEFLHTPFQPIPSELLEFFDAENWAKRFFTTDSAIYEQYEY
                     DLSSVKNK"
     gene            complement(998..1939)
                     /locus_tag="JXV47_002840"
     CDS             complement(998..1939)
                     /locus_tag="JXV47_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAX1488818.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVVLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNKHVDLIVALTKANQLDDMFRSIQSIITENTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEAKLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAEGM
                     VRTIVSEFASIAAKEGITLDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAVWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            2065..3186
                     /locus_tag="JXV47_002841"
     CDS             2065..3186
                     /locus_tag="JXV47_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAX1488819.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALGGTWRTIDGMDLLFRQRKISYLLTNWQGKNTAVIESAQVLGLDLLDKP
                     TDQTIRLASSYALGELIKDTLLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTRKLHLDRRNVLVSKVKVIIAADVTNPYTGQQGAAWQFGRQKGGTDTTLAFLD
                     KQAEKIAQQIKDVWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFELVSQITGLEKQI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDRELEGLFDFLPIV
                     LSIQLGPIDLEEAMEHRQTLEKTEILGQTLSRFFNILPK"
     gene            3444..4946
                     /gene="lsa"
                     /locus_tag="JXV47_002842"
     CDS             3444..4946
                     /gene="lsa"
                     /locus_tag="JXV47_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lsa family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAX1488820.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQAFVYFPQQTKDKERLTYYVLNEIMDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEIAKNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKKVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDALTMNSQVSHHKRLLSVENLQLGYENLLFEPVHF
                     TIEPHQRMAISGPNGAGKSSIIHYLLGTFNGKVVGEKSQPKHLTISYVRQNYEDNRGT
                     LAEFAKKNRVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYI
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLEKI"
     gene            5013..>5531
                     /locus_tag="JXV47_002843"
     CDS             5013..>5531
                     /locus_tag="JXV47_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAX1488821.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQALAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVVDRLNLPMTADERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECMEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELIS"
BASE COUNT         1799 a          997 c         1178 g         1557 t
ORIGIN      
        1 ctttattttt ttccttccat ccgctcttta gatgtttggt ccggaaaaga tttactacag
       61 tcggaattca ttaaatcagc tcgacaacag ttggcaaatt atcagctgat cgttttttta
      121 gattatggat ttgatatgga gatggctcga cgcgtgcgtc catttaccaa tgcaaaaatc
      181 gtgttatttt tttggaacca ctttaaagca gaacacgagg cgatgctgaa gcaggcacaa
      241 gatgaaccgg caatcgatga gatttatcat tttgattttt tagaagcgaa agaacttgga
      301 ctaaaacata atagttcctt ttattcgaaa catatggatt tttcttctag cgaaccaaag
      361 acggatctat tttttggtgc aacaaataac ggcagaaaag aacgggcaga aaaatataag
      421 caggaattta caaaaagagg tgttacgacc aattacttta ttcttccgct tcgaggaaat
      481 gaacaacctg gataccttac ttatgaagaa tatctgaaaa aaaccgggga atcgaggggg
      541 attctagaac tgttgcggga agggcagcaa ggagtgactt tgcgaacgtt tgaatctatg
      601 tattttcaaa agaaactagt gacagataat caagccatag ctcattatca gttttatcat
      661 tctgaaaata tttttttgct tcaagaacgt gatttagatg aattaccgga atttttgcat
      721 acgccatttc aaccaatccc atcagaactg ttggaatttt ttgatgcaga aaattgggca
      781 aaacgttttt tcactactga ctccgctatt tatgaacaat atgaatacga tctttcctct
      841 gttaaaaata aataaaagtg ccaaccaatc atagatgaaa ataaacaagc gcaattctta
      901 tggcaacatg agaattgtgt ttttcttttt gaactttcat gggggtaaaa aaatgagaac
      961 cagctgctga tccagctgat tctcatcaga gagcctttta ttctgcgcca aggattcctt
     1021 cttttgcatg gactaattgg gtcaaaaagg cacaatatgg tgtagcaata tcatattttt
     1081 gtccttttcg ccaaacggca ccattgatgt agtcgatttc agtcaaacga tggtttttga
     1141 tcaggtcttg gtacatagat gggtaatgca acccgatgtt gtcaggatca taagtagaag
     1201 caatatgttg gtacacttct tcttgatcta atgtgattcc ttcttttgct gcgatagaag
     1261 caaactcaga tacaatcgtt cgaaccatgc cctctgccgc tttttgcgca cctaattcag
     1321 caatattaca atccaatatc gtgcataatc catttaatgt tccgtttaca caagcttttc
     1381 gccaaatgga ataacgaaca ttatgactat agattggatt caattttgct tcttgaaaga
     1441 cttctacaac tttttttgta aatgcttcgc cttctggttc caagttctct agttcgattt
     1501 ctccatcacc taataatgtg acttttccgg gaccagctag accagctgtc cacatcgtga
     1561 tcccaaataa gatatttttc tttggtacat atttttccag tacatcttca tgacctaatc
     1621 cattcagtaa acacaaaaca taagtattct cagtaataat ggattggatc gaacgaaaca
     1681 tatcatctaa ttgattcgct tttgtcaagg ctacgatcaa atccacgtgt ttgttgcttt
     1741 cgatgatttc ttctggtgaa tagattggca gttttgcaac tacttctttg ccattaaagt
     1801 cagcaatcaa tccatttgta cgaatggctt caatgtgagc aggccagcga tcgatcaaga
     1861 cgacctcatt tccgctttga tgcaacatta atccgattcg gctgcccatt gctccggctc
     1921 cagctattgc gattttcatg ttttttctct cctttattca atgagttccc ttttagtata
     1981 tagaaaaaca gaagaaaata gcattgtttt gtttgaaaaa agtgaaaaaa agtgtcttac
     2041 ttaagaagaa agtgagggat atagatggat attttggcgg caatcgattc atttaaagga
     2101 agtgcttctt catttgaatt aaatcaggca gttctaaatg gttgggaaga ccgtaaagga
     2161 agaaaaatca atgtgccgat tgcagatggc ggagaaaata ctgcagaagc aatctattac
     2221 gcgctcgggg gaacctggcg tacgattgat gggatggatc tcttatttcg tcagcgaaaa
     2281 atcagttatt tattgacgaa ctggcaagga aaaaataccg cagtcattga atctgcacaa
     2341 gtattaggat tagatttact tgataaacca acggatcaaa ccatccgact tgcttctagt
     2401 tatgccttgg gagagcttat caaagataca ctgcttcaag aagtggaaca aatcattgtc
     2461 actttaggag gaagcggatg tagcgatggt ggtctaggat tactccaatc tttgggtgct
     2521 tctttagaag ggtacacaga aggaaatcct ttgttatcta ctagaaaact tcatttggat
     2581 cgaaggaacg ttcttgtttc taaagtaaaa gtgatcatcg ctgcagacgt gaccaaccca
     2641 tatacaggtc aacaaggagc tgcttggcaa tttggaagac aaaaaggagg aacggatacg
     2701 acgttagctt tcttggataa acaagctgaa aagattgctc agcagataaa agatgtttgg
     2761 gaggtggatt tagatgacat cccaggaagc ggagcagcag gcggtattgg cggagccctt
     2821 tttttgttag gagcgaagat ggtctctggt tttgagttgg tcagccaaat cactggatta
     2881 gaaaaacaga tcgaacaagc ggatgtcatc attacaggag aagggcggat tgatcagcaa
     2941 acaatccacg gaaaagttcc atatggcgta gcagtgcttg caaaaaaata tcgaaaacca
     3001 ataatcgcta tttgcggaag tagagaccga gagctggaag gactctttga ttttctcccc
     3061 attgtcttaa gcattcaatt aggaccaatc gatttagagg aagcaatgga acacaggcaa
     3121 acattagaaa aaacagaaat cttaggacag acactcagca gatttttcaa cattctcccg
     3181 aagtagttga caaaaacaat ttctttatgc tatcgtaatt tcaaatatag gacaaagtga
     3241 gggatccgtg cattgaaaaa ttaagtcgat tgatgaaagc tgcattcaga ctgtaccttg
     3301 tggagacaag ggagcagtgt gcagattttc gggattggct tggttctttc gatgtatggg
     3361 tctttttgtg tgccccaacc cttgcatcct ctttagccag ttctgaaaat aggactggtc
     3421 tttttttacg aggtgatgga ataatgtcta aaatcgaaat aaaaaatctg acattcggct
     3481 atgacagcca aggcacatta ttatttgaac aagccaatct aaactttgac acacaatgga
     3541 aactaggact tatcggacga aacggtcgag gaaagacaac tttactgaat atcctgcaaa
     3601 acaaactccc ttatcaaggg caagtgatcc atcagcaagc gtttgtctat ttcccgcagc
     3661 aaacaaaaga taaagagcgt ttgacctatt atgtgttaaa tgagattatg gattttgaga
     3721 tatgggaaat tgaaagagag ctccaactga tgcaaacaga tcctgaaatc ttatggagag
     3781 aattcagcac actatcagga ggagagaaga caaaagtcct actggcactc ttatttgtgg
     3841 atgacactca tttcccgtta atcgatgaac caacgaatca tttggatatc tctggcagaa
     3901 aacaagtagc ggcttacttg aaaaagaaaa aacaaggatt catcgtggtg agtcatgatc
     3961 ggggatttat cgatgaagta gtggaccatg ttttagcaat cgaaaagagc caactggaac
     4021 tttatcaagg gaatttctct atctatgaag aacagaaaaa acttcgtgat gaatttgaaa
     4081 tagctaaaaa tgaaaaattg aaaaaagaag tcagcaggct aaagaaaaca gcagctgaaa
     4141 aagcagaatg gtctcgttcc cgagaagggg acaaaacaaa gaaaaaagtc ggattcatcg
     4201 atacggaatc taggcgagtg aataaaggag cagtaggcgc tgatgctgca cggacgatga
     4261 aacgatctaa agcaatcgtg aatcggatgg aaacccagat cagtgagaaa gaaaaattat
     4321 taaaagatat cgagtatatc gatgctttga cgatgaatag ccaagtgtct catcataaac
     4381 ggctgttaag cgtagaaaat cttcaattag ggtatgaaaa tctgttattc gagccagttc
     4441 attttacgat cgaacctcat cagcggatgg caatttcagg tcctaacggc gcgggaaagt
     4501 catccattat ccattatctt ctggggacat tcaacggcaa ggttgtagga gaaaaatccc
     4561 agcccaaaca tttgaccatt agttacgtac gccaaaatta tgaagacaat cgagggacat
     4621 tggcggaatt cgcgaagaaa aaccgagtag actatcaagc atttttgaat aatctccgaa
     4681 agcttgggat ggaaagagat gtttttcata ataaaatcga acagatgagt atgggacaac
     4741 ggaaaaaagt ggaattggct aaatctttat cccaaccagc tgagctctat atatgggatg
     4801 aaccattgaa ttatttggat gtcttcaatc aagaacaatt agaacaactg attttgaacg
     4861 tgaaacctgc tatgttacta gtggaacatg atcaaacctt tctagataaa gtatctactg
     4921 agattatttc tcttgagaaa atctaaacct tgtaatctca aagacaacaa ggtatggtta
     4981 aggagaactt tgtcaacgaa ggagagaatc acatgcttta tgtaacgaga cacggagaaa
     5041 caacttggaa cgcacaagga ttagtttgcg ggcgagcaga tgtgccgctg actgaaaaag
     5101 gacagatgca ggcacaggca ctagcagaaa aggtagtaga tttgcctgtt ccaatcacga
     5161 aaatcatcca ttcccctctt caacgagcaa gagatacagc acaagcagta gttgatcgtc
     5221 tcaatttgcc gatgaccgct gatgagcgat tggtagaaat ggattttggg gattatgacg
     5281 gactgccaag caaagatgaa aactttcaaa aagcgcgttt agcgtttgct gtacgtttcc
     5341 caaatggaga gtcggtctta gatgtgtacg cacggatcgt tcctttattg aaagaatgca
     5401 tggaagacga agaaaatgtc tacttgttag tctgtcataa tgccttgata agagtgatca
     5461 atgcttattt tcatccaatg cctaatgaag ggttctttac attcatggta gacaatacag
     5521 aattaatttc t
//
LOCUS       DADGKS010000136         5441 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.141, whole genome shotgun sequence.
ACCESSION   DADGKS010000136 DADGKS010000000
VERSION     DADGKS010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5441
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.141"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..568)
                     /locus_tag="JXV47_002844"
     CDS             complement(<1..568)
                     /locus_tag="JXV47_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HAX1488822.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSN"
     gene            complement(902..989)
                     /locus_tag="JXV47_002845"
     tRNA            complement(902..989)
                     /locus_tag="JXV47_002845"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(955..957),aa:Ser,seq:cga)
     gene            complement(1134..1700)
                     /locus_tag="JXV47_002846"
     CDS             complement(1134..1700)
                     /locus_tag="JXV47_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAX1488823.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            1955..3286
                     /locus_tag="JXV47_002847"
     CDS             1955..3286
                     /locus_tag="JXV47_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HAX1488824.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGVFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSVLSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGILLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLSGIREIFDSSGKLTT
                     DFIANSGIGATLINMGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            3252..3602
                     /locus_tag="JXV47_002848"
     CDS             3252..3602
                     /locus_tag="JXV47_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488825.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(3694..4113)
                     /locus_tag="JXV47_002849"
     CDS             complement(3694..4113)
                     /locus_tag="JXV47_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HAX1488826.1"
                     /translation="MMTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHTDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(4114..4458)
                     /locus_tag="JXV47_002850"
     CDS             complement(4114..4458)
                     /locus_tag="JXV47_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HAX1488827.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVEWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            4808..5404
                     /locus_tag="JXV47_002851"
     CDS             4808..5404
                     /locus_tag="JXV47_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAX1488828.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT         1513 a         1007 c          930 g         1991 t
ORIGIN      
        1 catttgatag cgagcgataa ttgttcagat taaataattg ataatcaaat ggcggattat
       61 ttgtcaacac accgacagga ttatcatata aatgaagtcc atctttcata ctttcaatta
      121 ctatcgattt ttctttatca gctaataacc agtgtaaagg tgacaagggt agtttttcac
      181 taaaatcgat attgactaga ttgatagtag ccaataattc tttagcttcg tctatggttg
      241 agcattgccc tagtatccat ggaataaact caaatggtgc aacgttatct tttccttctt
      301 gtaattcttt ataatcagca ttgccaggaa aattcagtcc tgccatactc aacccttttt
      361 catttgtagc ctcataatag agtggatagt tggatacccc agctgctatt cctatcattg
      421 cataatgttt atctaaattt tttacctttc taaaatcgaa acgataattt cttggagtaa
      481 tagtgaccac ttcattataa gacatctcat aatcaaaatt ccttccaaaa taatggtctt
      541 tcgttgcata agtgattgcg gtacacatcg tttcccctcc taaaacaaat cgtttttaca
      601 cttttatctt acatctagta ttttttttat caaaaaaagg ccaaagaaga ttgatttact
      661 agcatttata aaaaatagta ctcaggggga atcaaaaaat attgtaggtt aaaagtacaa
      721 caataagggg ctgtgacaaa agtcttgtca cagcccctta ttccgaacaa acggtgttca
      781 aaagcttgca tctgcggtaa taagcccaat caaacgaaaa aataggaaaa gctatttttg
      841 tttggccgtt cttattactt gatgcaggac agcttcttca caacctctaa tcgttgatat
      901 aaggaaggta caggatttga acctgcgcgc cggtattagc cggttcgccg gatttcgagt
      961 ccggtgcatt accactctgc caaccttccg taagtactat ttttaaactt ttttcacgaa
     1021 atgtcaagcc tatttctaat agataaataa cagaaatcgc tttttttagc aaaaaagtcc
     1081 attgacagtt tgcagccaac ggacttaccg atcaaattca tactgataga acactatctg
     1141 attatttcag gattatctaa tgctaaaatc gagtcaattg tccgtttgat cagtgcaatg
     1201 atttgttctt ctgttggatg catgatgttt gatgacatca atgacgctaa gccagtcact
     1261 gctacccatg taccagtatg cagagcatcg acatattcat ccgataattg attgtatctt
     1321 tcatcttctt taactatttc acggaaataa ttgtatgaaa aatcatgcat tttctttccg
     1381 tccccatgtt catcaatgta caatgccatg taaagactat gatgcttttt tgcaaagtag
     1441 atatagttca aaccgagatc aatgatttta tcaccagtac gttcaatagg gaaaacatct
     1501 tcttttagtt gttcaaagat agaatccagc aacgtatttt ttaaatcttc catgtttttg
     1561 aattccagat aaatcggctg tgtcgaaatc cccatctttt tagcaatatt tctcgcagta
     1621 aatcctttaa acccttcctt tgcaacaaca tcataagcag cttttagaat ttgatccttg
     1681 gtatagactt ttcttctcat taaaactccc ccacttcttt actgcagtat atgttgtttt
     1741 attgtaccct atttttagca ttttttgcaa acattttact caaaacgtta tattttaaat
     1801 ttttttcagt cttctttaac ttttttttgc aaaattaaaa aaatttggtt aaattcaatg
     1861 ggttccctta catttttagt tttgacctaa atgatagttg tccaaatctt tcatttcaag
     1921 ttatagttaa agaaaatgaa aaagaaggtg tgtaatggaa aacgaaactg acgttattta
     1981 tattcatcct caaaaacgaa tcgtttcaca gaaaagaaag tatttttatc ttggttttac
     2041 aggtgttttt tttcttttta ttggcttgct ttctaatact cctactgata attggagtgg
     2101 attgctaact attcttacct cgccaagcaa tcttttgaca gattattttg ctttaggtgt
     2161 tttcggaagc gcattcataa atgtagggat tttgacctta ctttctgtgc ttttagctta
     2221 tcggcacaag gtgattttaa acggtccctt atttgcttcg attctaacag ttaccggttt
     2281 ctcttttttt ggcaaaaacc tttataattc tatctcaatc attttaggtg tgtatctata
     2341 cgctgtattt gtcaataaac ctttttctca gtacatcatg atcggactgt ttggtagcgt
     2401 attatcaccg gtcgttagtt atatcacttt tggtatgcgt tttcctttac tgataggtat
     2461 tttattgggg aatttagctg gcatagcaat tggtatactt cttccgccct tagctgctca
     2521 aactttagtt ttccatcgtg gattcacact ttataatatt ggattcacct ctgggttgat
     2581 tgcgatgact tttactgctg ttttgaggtt attcagctat tcaatcgtcg aaaatacatt
     2641 ggttttcaat gaatatcact ttcctctcat ttggattatt tttggctttt tttcgctgac
     2701 agtcggaatt ggtttctatt ataattcctt tcggctttcg gggattcgag aaattttcga
     2761 ttcatctgga aaattgacaa ctgatttcat tgctaattct ggtattggtg ctactttgat
     2821 caacatgggc ttagttggtc tgatgctgtc ttcttatgtt ttgctggttg gcggtcagtt
     2881 aaatggacct gtcatcggtg ctattttatc tgcggtgggt ttcagtgctt ttggttgtca
     2941 tttaaaaaac agttttccga tactagtcgg aatatttatt gcttctttgt ttggaacttt
     3001 tcatgagatc accagtactg gcatgcttgt tgcagctgtg tttgggacag gtcttgcgcc
     3061 cataagcggt ttttacggca gtttttacgg tgtaatagct ggtgtgctac atattgctct
     3121 tgtccataac gtcagcactt tgcacggagg actaaatcta tataacagtg gtttttcaac
     3181 tggtttcgtt gcaggtatcc ttgtaccgat actagataac tttaccgctg tcagaaagga
     3241 aaaaaagaca cttggaaaaa gaattatcaa aaagaatcat cgatgagctt cttacttatt
     3301 tatattccca tgaaataact gaaatacgta ttggagtaga atttgctgag gaagggcttt
     3361 tcatagagat acagggtacg gcagaaactc agccagaaga tttagatgta cttgctgatt
     3421 tgctgaacaa tcctcgggac cctagtatgg aaatctacta tcaagaacta ttaggtaatc
     3481 cccgacatga tcgggaagat tatcatctgt taggtagttt gattgatgac gtggaaatca
     3541 tgtatgccca gccgattatc aatattaaga tctttcgacg tgcttctcat tcctattatt
     3601 aaccctattt tctatttata aaagactgaa tcaaaaaagc agctcctgaa agttcgatta
     3661 aaatctactt tcaggagctg ttcaagcttg acattattga ttttccaatc cttcatacac
     3721 ttcatctgtt acaggttcta aaaactctga attaccagca gtgatcgcca aatgttcaaa
     3781 ccaactgtct tttgtcgcac catgccaatg tttaatccct ttgtgcgtta cgacgacatc
     3841 tccagccatt aatcgtcttg ctggctttcc ttcttcctga taccagcctt ctcctccggt
     3901 cacaagtaag atttgatagc cgtctgtatg gacatgccag tgattgcgac aacctggttc
     3961 aaaagttaca ttacctacac caacagaaac ttcgggatca ttcactaaca tattcagata
     4021 gctttgcccg gtaaatactt gagcgtaagc ttcgtttttt tcacctgctg gaaaaatcac
     4081 gccattgtgt atttcttcgt gttttgtcat catttacgcc tctttcttat cttcgctatt
     4141 ttcttctaaa tagatttctt ttgctaaact aaaagctgac caagcttttg gccattctac
     4201 ataaaaagct aaatgggtaa tgatttctgc tatttcttca ctagtaatgc cattttgctt
     4261 gccaatcttc agatgagctg gcaattgttc aaaatttcct cctgaaatta atgcagatat
     4321 ggtgatgata ctacgctgat gagcagataa ttcttctctg gaccatactt gtccaaataa
     4381 aacatcatca tttaattctg caaattttgg tgcaaaatct cctaattgat ctcgtcctgc
     4441 ggtttgtttt tctgccattt ctcttattct cccttcacga ctgttaggtg attcaactat
     4501 ggttctaagg caactttatt ttctattgtt tcttcgcatt tcattttaaa tgtagtcttt
     4561 cagcctgtcc aatgcttagt ttattcagtc gatatgcttt ttaagcatag ttgctaacgc
     4621 tttttttatt ttaaaaaaaa caagttatta aataagtctt tagttggatg tttttttgag
     4681 atcaatcttt tatacttatg atgaacttac aaaattgttt gttttctgtc atatcaaaaa
     4741 atggcgcagt tagttgcttt tctagtaaag tatagttaac aaagaacctc taaggagttg
     4801 atgaataatg aatattgctg cctctcgaaa actgataaat ttcatatcca ttatcggatt
     4861 aggcctatca atcgcgctga cgatttattt tattaattta ggtgttttca aagatttgaa
     4921 tgcgttaaga ggattagtag gtgattccat cattttagga ccgattattt ttgtcttcat
     4981 ccaaatcctg caagtagtta ttccaatcat tcctggaggg atcagtactg cagctggtgt
     5041 cctgatattt ggcccttatg ctggatttat ctataactat attggaatct gcattggttc
     5101 gattatcatt tttctgctag ggcgtcgtta tggaaagcca ttcatacttt ccatgattag
     5161 cgataagaca tataacaaat atattggctg gctggataat caaaaccgtt ttgagaagct
     5221 gtttgctcta gctatttttc ttccagttgc tcctgacgat gcgttatgtt tgatggctgg
     5281 attgacaaac atgtcagtga aacgatatac actaatcatt ttgattgcta aaccactgtc
     5341 gattttctta tatagtatgg ccttgattta tggaggtcaa tatctaagtg gtcttcttgg
     5401 ataatattta ttttgtaaaa ttagtcattg attgacaatg t
//
LOCUS       DADGKS010000137         5342 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.142, whole genome shotgun sequence.
ACCESSION   DADGKS010000137 DADGKS010000000
VERSION     DADGKS010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5342
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.142"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(61..279)
                     /locus_tag="JXV47_002852"
                     /pseudo
     CDS             complement(61..279)
                     /locus_tag="JXV47_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(545..739)
                     /locus_tag="JXV47_002853"
     CDS             complement(545..739)
                     /locus_tag="JXV47_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488829.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            2091..3131
                     /locus_tag="JXV47_002854"
     CDS             2091..3131
                     /locus_tag="JXV47_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepA"
                     /protein_id="HAX1488830.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
     gene            3955..4287
                     /locus_tag="JXV47_002855"
     CDS             3955..4287
                     /locus_tag="JXV47_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HAX1488831.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            4906..5247
                     /locus_tag="JXV47_002856"
     CDS             4906..5247
                     /locus_tag="JXV47_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HAX1488832.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         1943 a          728 c          900 g         1771 t
ORIGIN      
        1 aggtattttt attatatata gatttaacat atgtcggtcg gttgattgat atagctaaag
       61 ttataactca accgaagccg attcatctac acgaataaag ttgcgagtgt tctcggctaa
      121 ttcataaaaa ttgttatgtg ttccatatag caatactgga ataactttat tttcttgaat
      181 ctcataagca actctataca cggtgaccgc atacttaaat ccattagacc aattacctga
      241 taaacctcca gttttttgct cttacttaaa tggatcaatg gcaatttcat cacaaaccta
      301 tagaggatga gtgacttctg cctaattacg ttaaaaaata ttgaaagtaa ctctatgtag
      361 caaaaaatat ctagaatttc atttcctcaa aactgatcga tattgtatct aaaaatatat
      421 actacctaaa ataggtagta tatattaaaa tatgtgcttt tgttagaaaa atcaatacat
      481 aaattatcat atctgtatat gtcatttagg tatttcagtt atgttataat agttttgctg
      541 tctgctaccc cggcctaatc tggcaagggg aggaggagat ataatgaaat acctttttga
      601 ttttgttttt gcaatcaagc cacttgcaga tgtagtgtgc agttacctct gcaaatggct
      661 tgattgcaaa attgccaaaa aagacagtaa gcctacccgt taattctata atatagaaac
      721 gtaaaaaaaa ccccatcagc ctgcacgctg atggggtttg gtgatataat gaaatacctc
      781 tttgttactc ataattatac cataattagt cacgaatgca accaatagaa aaaactactt
      841 agaacggtag atcatcgcta ataacaatgc attgtccacc aaatggattt tgtgaagcat
      901 taaatacatt gttattaatt gtcgctgctt ttaactaggc ctctcccctt ctattataaa
      961 agaagatata tatcatttct taattaccta ctaccttaaa ccaaaattta agtactacct
     1021 aatttaagta gtacttaaac aatctaaaaa atagttatcc caattgttat gcttttataa
     1081 tacgattatt tgtaacaaaa tgaatattat ataattaaac actaccatat ttaggtagtg
     1141 tttaattatt agcaaaacaa aaaatattta ttctattctc ttaacttcaa ctaagttatg
     1201 ctgcacacct ttatataaat catatgcaac tcattagcta gacaaactac aagcatgtag
     1261 ttttatctgt taattatgta ctacctaaat aaagtagttt ataattagca agtatatata
     1321 tttaaaaatt taagattaat ttttttatga cttgtacaaa tttatctgat attctcttat
     1381 taagaactac ctaatttggg tagttcttat tttttacatt ttaagtagta tttaattgca
     1441 atttggtagt atttttttat tatcttattc ttagaacggt agtacttaat ataaatatag
     1501 gtagtatcta atttaagtat taatggtagt atctaaatta acaggtagta tgtaactact
     1561 ttaaagtaat ttttttcaga ttaacacagt agtatcttat taaataagtt aattttaatg
     1621 gtagtacata attattatat atatctgaca ttggtagtac ttattgtatt ttttagtagt
     1681 atataatcta ttgttttcta gcctaaagcc ttgtcttata agaataatat aatatatact
     1741 actgaaataa ggtagtatat attactagta atggtagtat gttttatatg cataaggtag
     1801 ttcttaattt attttttgtt ttgacactgg tagtacttaa ttatctttaa ttttaaaact
     1861 aaattttatt catacgtttt tctggtagta tttaattata aataatattt atttaaagta
     1921 gttcttaatg actttaaagg tagtacataa ttcattttat ttctgatttt aggtagtatt
     1981 taattaaaaa acagttttaa tgcgtttgca ttttttattt atctttgcta ttttcgaaaa
     2041 gagtaggtaa ttttacataa ataaaacaac gtgaaagtag aggatctaca atgactgatt
     2101 ttaaattttt taaggcggat agagtttaca acgaattatt ttatcaattt ccaaaagtct
     2161 ttattgtttc tgacgaatac aaaaaaatga aagattcaac taagattgcc tatatgcttt
     2221 taaaagcaag attagagatc gcaatcagca aacggcaaat cgatgaagaa ggtaatgttt
     2281 attttactta tacgacaaat gaactatgta gagtattaaa ctgccaaaaa caaaaagcga
     2341 tagcaatcaa aaaagagttg gaatcctttg gtttattatt acaaaagcag atgggattta
     2401 acaaacagtt agggaaaaat aatcctaata gactatatct agcagaatta aaagtctcag
     2461 aaaatgatat ctacttactc gaaaaatttg atagagagaa tagggaaaac gttgataaat
     2521 cagagggtat gaaaatcata cccaccctcg acgaaaaatc agacgctgaa tcccttgggg
     2581 ctcaagaggg tatgaaaatc ataccgtgcc aaaacgttga taaatcagag ggtatgaaaa
     2641 tcataccaga acttaataat aatatattag acactaatag acacaatata gacactgaaa
     2701 aagaccgcct acaagatcaa ttgttgttag acaattttga gacaattatg acaaacgaca
     2761 gcattgctac gtttgtccct gaacgagtat taaatttgat aaaaacattt tcttcaagtt
     2821 acagtgaagc tcaaaaaacc gtccagacta ttcataatgc aaagaaaaaa gctgaaatag
     2881 aaagtgatat ttcgatagtt tttgaagaac tcgatagtta ttatgtcaat gcagaacaag
     2941 aattatacac gacactgtta aaagcctatc aaaaattaaa aaccgaaaaa gtcgaaaata
     3001 tccagaacct gatttttgtc tatgtaaaaa attggtttat cgaaaaacca atagctgcta
     3061 aagtatcaag tgaaaaacgt ttgaattatg caagctcccc aagcactatt acgaaagact
     3121 ggttagagtg aaactttact gacaaagtga ttgttgcttc atggagtaac attaaaatta
     3181 aaaatttttt attattctaa ttatattacg aatattacaa aataatagct attttaatag
     3241 aatttataag ttaaaatatt atgataaaaa tcacaaacgt agccttttac gtcataagtg
     3301 ttaaaagaaa taattaattt caaatataga aaagggaacg tatgtttgca tactcctttt
     3361 ttttgagtta taataatacg cgaagagaga taatttcatt atttaaacaa gctaaaaatc
     3421 ttgatattac ttcttttcag gcaatacgaa tattattcgc ttacattttt tgtataaatt
     3481 taattgtctg ctatgcttgt gatgaattga ttttcgtttt gcacttttgg atgataaatt
     3541 tggacaattg aaaatacaaa aaaaagaaag gcggtatgaa ctcggaaggc tggtaacctt
     3601 cgtcagcgtt catacacggc attaagattt ggcccttaat gcgttaacct ttcagtgtta
     3661 cggtattacc cgcaatggat ttagtataac agatattcaa aagtgatacc actttttttg
     3721 gctgtgttaa ggttaaaaat acgtgatatt acgatgaatc tatgcctaag cataatgtta
     3781 taaaaatgtc cgtgtggctc tttgccgtat gacgaacgct gaaattagag ggaacgcatg
     3841 tttggatgcg ttccctcttt tttgtttgtc atgaacgaaa atcaattctc tatttttgaa
     3901 aaataacaag aaaaacttgt taaaaatatt taaagaaatt gggtggttta ttttatgtca
     3961 tatacaggaa ttttgagtct caaagatatt tgtcactacg gtaaacggtg taccgctaca
     4021 gagaaaatca cgaagaaact atcaactggc caaagtaaaa ccgttgtgca gtgtaagaaa
     4081 tatataatcc agaaagacaa agtctcagag gaaatgattt attacattgg gaaacaaaag
     4141 caaataattt taaaagatcc tatcccctta aaagagctat atccaacaat caaacatgtt
     4201 tatgaccaaa acggtgtact gattggtcga agaaaaaatg gagtcttgcg ttgtaccgca
     4261 aaagggatgg ggcgtttgat cggctgaatt gatcattctc ataacttgta ttttatcgtt
     4321 tttcgcttgc ttgaaaatat tgtcgagact tctaaaggaa cttagagtca ctagaaaaat
     4381 aaggagtaga cttgatctat caacaattcc cttcggggag tgacggggta ggttttaacg
     4441 attggtaacg taaaaaattg gtcaatcgag taaatgcgct tgtttggata gtggtgaaat
     4501 gaatttgtgt aaataataag cgcagagtaa acaagaggga atttagaagt tagacaagtt
     4561 agaatagcgt ctagattaat catgagcagc tactaaggga tctagacttt gacgcaaact
     4621 catggaataa ggagtaggtc ttctcgtaat ggggaggacg cacaagaaat tgtgtcgtgt
     4681 gctgcagtac atgtagatac ttgcgaggac gttgattatt ggatcaatcg agcatttacc
     4741 gctgtctact agggtttctc gtttcggacg ccataaacga gtcgaaattt tttatgtatt
     4801 tttaagtaaa cgaaaaacga taaaatatga acaagtcctg aataaagtga aaaaattgat
     4861 ataaaacata gagaaaatga aatttacgta atggaggaat gacaaatgaa aaattatgat
     4921 ccgaatatac gattgggcac acatactatt aaggtttctt tccaacgttg ggattacaaa
     4981 ggatttgtga cgtttagaag gggcggaaat tgtaaaggat tagatgtttt agcattagac
     5041 gaggatgatt tatacgatca aacattgact gataatccaa ttggattcgg cttgctacct
     5101 gaagatgatg aaggtaatga atggtttaaa atgacgctta tgaatgataa tggagacgaa
     5161 ttatctgttg aagatacttg gtcatatttg agtgattata ttgtcagctt tgaaatcatt
     5221 gaatttgtag cggataaaga agaataaaaa ctggaggaat aaattttaca gataaaggct
     5281 tagaaggagt cacgacgatt aataaaaagg tagtattacc ttaggcattg agtaaggaat
     5341 tt
//
LOCUS       DADGKS010000138         5320 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.143, whole genome shotgun sequence.
ACCESSION   DADGKS010000138 DADGKS010000000
VERSION     DADGKS010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5320
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.143"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..521
                     /locus_tag="JXV47_002857"
     CDS             <1..521
                     /locus_tag="JXV47_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAX1488833.1"
                     /translation="FVSRKQNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFY
                     NLKKFNHPLVFESDSSENHYNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLI
                     LTNQGSLYRFKGLIALQEQDFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERI
                     KQSFDKLLAESK"
     gene            551..673
                     /locus_tag="JXV47_002858"
     CDS             551..673
                     /locus_tag="JXV47_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAX1488834.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            691..2214
                     /locus_tag="JXV47_002859"
     CDS             691..2214
                     /locus_tag="JXV47_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAX1488835.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            2238..2477
                     /locus_tag="JXV47_002860"
     CDS             2238..2477
                     /locus_tag="JXV47_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488836.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(2670..3131)
                     /locus_tag="JXV47_002861"
     CDS             complement(2670..3131)
                     /locus_tag="JXV47_002861"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAX1488837.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(3326..3544)
                     /locus_tag="JXV47_002862"
     CDS             complement(3326..3544)
                     /locus_tag="JXV47_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1488838.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            3662..5278
                     /locus_tag="JXV47_002863"
     CDS             3662..5278
                     /locus_tag="JXV47_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAX1488839.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
BASE COUNT         1861 a          796 c         1032 g         1631 t
ORIGIN      
        1 tttttgtgtc tagaaaacaa aacttgaatt tatctgcact aaaaaaatta cagagagaaa
       61 tcaaaagtat taacccttta tccgatattc gaatgttcac acatagtgaa acgattcaaa
      121 aaaaggattt ttataatttg aaaaaattta atcatccctt agtttttgaa agtgattcat
      181 cagaaaatca ctataatggc aaatactatc atcaacacca tcaagtacat gagtttaaat
      241 caattctctt aacttcagat caagacataa aaaaagattt tttactccaa tggattgact
      301 ggctgatttt aaccaaccaa gggagcctgt atcgttttaa aggattgatt gctttacaag
      361 agcaggattt tatagttgcc atgcaagagg taaacgaaca ggttaatttt caatacacca
      421 ctcgacaaaa agaccaaacc actattattc taatcggaaa aatgttggat gaagaaagga
      481 tcaaacagag ttttgataaa ttactggcgg aaagcaaata atgataagta gtgattgggg
      541 gtaatttcta atggagaaaa cggatatatc tagtgcatat cgacgactta aaagcccgaa
      601 tattaaaact agaaaaaggg cattaaaaat tatcaaagaa cataaacgaa ataaaatgaa
      661 gaaattagca taattaagga aggaaaaaga atgaagaaaa tcagtgtagg acttattggg
      721 atagcagctc taggattatt gggagcttgc tccagcacta atgatgcaaa agtatcgaat
      781 gataaagatg gaaaattaga aattgtaaca acattctatc caatgtatga tttcaccaaa
      841 aacatcgtcg gcgatgaagc gaacgtggat ttaatggttc cagcgggatc agaacctcat
      901 gactatgagc cctcagctaa ggatatggca aaagctcatg atgctgatgt ttttgtatat
      961 cataacgaaa acatggaatc atgggtacca aaagctaaag aaagttggaa gaaagctggg
     1021 cctaatgtag tagaaggaac aaaagacatg attttattgc caggtagtga agaagaagat
     1081 catgatcacg gagaagaaga tcaccatcat gaactagatc ctcatacgtg ggtttcaccc
     1141 aaaatggcaa ttaaggaagt ttcaaatatc aaggatcagt tagttaaatt gtatccgaaa
     1201 aaagcaaaag tatttgagac aaatgctgaa aagtatttga ctaaactgaa acggttggat
     1261 gctgactata ccactagtct taaagaagcg aaacaaaaaa gttttgtgac gcaacacgca
     1321 gcctttggat atttagcttt ggattatgga ttgaaacaag ttcctattgc tggactaagt
     1381 cctgaagaag agccatcttc tggtcgatta gctgaattaa aagagtatgt taaaaaaaat
     1441 aagatcaatt atatttactt tgaaaagaat gctaatgata aaattgcaaa aactttggcc
     1501 aacgaagctg ggataaaatt ggaagtactg aatcctcttg aaagtcttac aaaagaacaa
     1561 atggataatg gtgaagatta tgtttcagta atggaagaca atctaaaagc gttagaaaaa
     1621 acaactatgg ttgctggtga agaggtagtt ccagaaaaag aagcgaagga tgaaaagaca
     1681 gttgctaatg ggtactttaa agatgccgat gtgaaggatc gcgaattgag tgattataca
     1741 ggcgaatggc aatctgttta tccgttgtta aaagatggaa ttttggatga agttttcgat
     1801 tacaaagcaa aaatcaataa agacatgaca gctgccgagt acaaagatta ttatactact
     1861 ggctataaga cagatattga tactatcaac attaaagaca acaccattga ttttgtagtc
     1921 aacggtgaac atcatcaata cacatacaaa tatgttggat acaaaatttt gaattatgaa
     1981 aaaggaaacc gtggtgttcg ttttaatttt gaaactgatg atgcaggtgc tggtcgtttt
     2041 aaatatattc aatttagtga tcatggaatt gcaccaagta aggcagagca tttccatatt
     2101 ttctttggtg gagaaagtca agaaaaactc tataatgaat tgcataattg gcctactttc
     2161 tatccagctt cattgtctaa acatgaaatt gctcaagaaa tgatggctca ttaaaattca
     2221 atttttggag gaaatacatg gtaagaaaag tattattgtc tatggattcc aagaatattg
     2281 atgcttatcg gcgttatcga tttgcaaagc aaatgagatt aaatgggagt acattagctg
     2341 atattgctgc aactttacat gttagtattg acacagttca tagagtatta aaacgggatc
     2401 ctgattgttg ttttatcaag gtcaatactg gaagaagtag acgtttagca aaacggcata
     2461 atagcttggc caattaattg ataataccag agtagatcat ttttccctta tttggatttg
     2521 atctgctttt tattatgtct tgaattgtca aatcaagcgc aacactttat caaagaagac
     2581 ttcataaggt gttctccaat ctaaacactt tctaggtctg ttattcagtt tttcaatcat
     2641 ctgatttatc gttgagttat ctaccgtagc tatctctttc gattttggca agtattctcg
     2701 aatgagtcta ttcgtatttt aatttgttca ttgttgccaa gggcatgagg atctggaaaa
     2761 taaaagggca tattattcaa tgcttctgta actgcgaaat gattggagaa ttcttttcct
     2821 ctatctggag tgatcgtttt gaccgcctca tttggaatac tgcttaaaag ttcaatcatt
     2881 ttctcgctca cataagcggc tttctttctg gggaccttct ttcctgctaa aaggaagcat
     2941 gattttctgt ctgtcaaagt cactaaacaa gtaccaccag ttttgccagc tacaatatcg
     3001 gctttccaat gaccaaaatc acttctatca tctgcggatt ttggacggcc atggatcgaa
     3061 tgagtaaggc aaatctttcc acgagactcg acatgatttt ttgtatgtct tgtttttcct
     3121 cgatggtgca atgaacggat caggccttta ttgccgtgtg agaggggttc tgtatcgaaa
     3181 agatcattgc aaattgcacg ttagatcgtg ataaaactaa ttgaaaagtc catatgttca
     3241 tgcttcaaac gattcgagat ttcctctggc gaccactgaa aatcgacaaa taaatgacga
     3301 acaattgacc aaactcacgg atcatttaga atgtgataac gtccgcattt ttttcttcga
     3361 taagcataat ttttttccgc tttggaaggt gaatagtttt tttcttgttt cttctcagtt
     3421 catgtaaaat agtaaacggg ctatgctgaa tgtcgttgcc aattatacta atagaaaatc
     3481 cttcttcgtg aagcagaaag attctttctc gttcgagtat agtaagatga cgatactggc
     3541 tcataattat tttccttcta ggagtgttct cgacaaactt atactagttg gatatcgatt
     3601 atgactcatt tttatgtgtt gcacttaaag tgtaaattca aggtatagaa agaggttccc
     3661 tatgaaaaaa atacctatta caatcttaac tggctatctt ggttcaggaa aaacgatact
     3721 tctaaatcat attctgtacg gtgatcacgg aaaggaaatt gctgtcattg taaatgacat
     3781 aggggaagta aatgttgatg gggtattagt cgacaagaaa ggttttaaaa gaactggaga
     3841 aaaacttgtt tcgatgccga atggatgcat ttgttgtaca ttacgcgaag atttgattgt
     3901 tgaactagat caattagtgc aattttctga cttgaatcaa attgttattg aagcttcagg
     3961 aatcagcaaa ccaattccaa ttattcaagc aattatatta gctaaaaacc ctttagacat
     4021 tgatttgacc caacgattag agattggtgc cattattata gtagtggatg taaaacgttt
     4081 ttgggataat ttcgaaacgg gtgaaaagat tcaggaaaga aaagctgaag gtaatgtagt
     4141 tgaagaagaa caggatattc gtggcttgtt aattgatcaa ttcgagtgtt gtaacatatt
     4201 acttttaaat aatagtgact tagtgtcaac caagacgatt tacaaaatta acggtctaat
     4261 tgctaagtta cagtccaatg ccaaaataat taggacaatt aaaggtgaag tagacttatc
     4321 gaaaattcta aatacaaatc tttttaatat agatgagact tcctattcag tgggctggtt
     4381 caaagagtta gagcttggct atcaaaatca tattcctgaa acagaagaat atggtatctc
     4441 aagttttatc tatcgaaatc ggttactcct tgacgcacaa aaatttgccc atcttacgga
     4501 taaaaatttt cctggcaata ttacaagagc aaaagggttt ctttggtttg cccaacatag
     4561 tgatttttcg acgatctttg aaacatcggg tagctataaa agtattgaat cattaaatta
     4621 ttgggtagct agtttaccta aaattgagtg tcaaatgatt atacaaaaaa atcccgaatt
     4681 gaaggaagcc tggcatccgt tgtttggtga acgcattaat aaactagttt ttattggtat
     4741 gaagatggat caacaatgta ttaaggaaca acttgagggt tgtttaactg attctcttaa
     4801 tgcagataat ttccgaaaaa tttcaccatt tccatggaaa aagtctaata tgtttagcca
     4861 gatatcgtta atgaaatttt taagaaaagc tggtgtcaag ataggcgatg tcataattat
     4921 tggcattttg attattacct cttttattcc cttatttgta ttctctatag aaaaggagaa
     4981 tgaaacaact gaagatgcta tcaaatatgc catcgttcga attgatggca aggaaatgga
     5041 tcgcttcgat ttggataaga tcaatcataa actcgtgaat tatcatcctg cgaagggaca
     5101 atataatatt gttgagatta aagatggaag aattcgagtt aaagaagata atagtcctga
     5161 tcaaatcgcg gttagaactg gatggatctc aaaacccggt caaacgagta tttgtttacc
     5221 ccataagtta gttattagta ttgagaaaaa agaaagcaca gattactaca tttactaatc
     5281 tggaaataga tgaggaggtt tttaataaga aaaagatatt
//
LOCUS       DADGKS010000139         5312 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.144, whole genome shotgun sequence.
ACCESSION   DADGKS010000139 DADGKS010000000
VERSION     DADGKS010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.144"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(73..1221)
                     /gene="nagA"
                     /locus_tag="JXV47_002864"
     CDS             complement(73..1221)
                     /gene="nagA"
                     /locus_tag="JXV47_002864"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HAX1488840.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1297..2133)
                     /locus_tag="JXV47_002865"
     CDS             complement(1297..2133)
                     /locus_tag="JXV47_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1488841.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2317..3534)
                     /locus_tag="JXV47_002866"
     CDS             complement(2317..3534)
                     /locus_tag="JXV47_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAX1488842.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            3917..4000
                     /locus_tag="JXV47_002867"
     tRNA            3917..4000
                     /locus_tag="JXV47_002867"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3951..3953,aa:Leu,seq:gag)
     gene            complement(4240..5237)
                     /locus_tag="JXV47_002868"
                     /pseudo
     CDS             complement(4240..5237)
                     /locus_tag="JXV47_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1654 a         1082 c          838 g         1738 t
ORIGIN      
        1 ttttactaga acacaaaaaa aaccttaaaa ccaaacttaa gaagtttagt tttaaggtta
       61 acttaaatta tattatgcgt ggaaacgttc cacgccatct agataagttg cttccaatgt
      121 catatcaggg ttcaatacga taaagtctgc atcgcgtcct tgagcgattt ttccacatgt
      181 atcatcgatt ttacagctga ttgctggaat cagactagcc atcatgactg cttgttctgg
      241 tgttgctaat ccccagtcta caacattttt aattgcttct ttcaatttca atatacttcc
      301 agctaagttg ccagattcta gacgtgctgt tccttctttt actactactg gaaattcgcc
      361 taaattgtaa tttccatcag gcatcccacc ggccatcata cagtctgtaa ttaatgcgac
      421 atgatcatgt cctgcttttt ccattaggat tcccgcagca tttggatgta catgatggcc
      481 atcacaaatc aattcagaaa agacatgttc taaagataat aacgcaccca ccatacctgg
      541 ttcgcgatga ttcaatccac gcataccatt gaaagcatgg acaaatacac ttgcgcctgc
      601 ttcaacagct ttttgcgctt cttctagtgt agcattactg tgtcctagag aaacaactac
      661 tccttcttca gtcacttgtt tgacaaactc ttctacacct tgacgttccg gtgctaaagc
      721 aatttttttg attaaaccac ctgaagcttc ttgccattca tggaaagtat ccaaatcagg
      781 atccccgaaa taacttgggt tttgtgcccc tttgtgttct tctgtgaaga aaggaccttc
      841 aaaatagatt cctttgattt tagctcctgg tgcttcctga tacattttgc cgattgtctc
      901 agctacatct tttaaacgtt ctttgcttga cgtcaatgtt gttggtaaaa atgaagtcac
      961 tccacaagat aacagacctt cagacatcac tttgatgcct tctgcatcat tatccattac
     1021 atcatgattc atatagccgt gaatatgtgt atctaccaaa ccaggagcaa tccatttgcc
     1081 gctttggtca atgatgttga cttctccctc aggtagttct ttggtgtatt caccaaaaag
     1141 tccatcggta atttcaagat agcctgcatg tttgacacct gacgctaaaa agaatttgtc
     1201 agcatagata aaagttctca ttctattctc tccctttgtt tttctacctc taaagtactc
     1261 ttatttagag aagaagtcaa gaatggtcta caccatttac aaattttttg aaatttgttt
     1321 cacagcttgt gctaagcctt catagaatgc tgctctttct ggttcttctt tacgcttgta
     1381 tattaagctt ttaagcacaa ataaatcatt gaggtaatag tagctattct tctcttgagc
     1441 ccaatagatt ccttgattca cctgttctaa cgcttcgtcg atttcatttt gatggaataa
     1501 gaaatttcca taattataaa aaatttgcga aaattcactt tttgatcgtt catcagctga
     1561 ttgatgcagc agttggatgc ttcgactcaa atagtagcgt gcttcagccg tttttcctgc
     1621 cacaccatat atttttccga tacaactaat cagttgtatt tctgtgtcag aaacatggat
     1681 tctttctttt tggctagagt agcttaatgc ttctttcaaa taataaaggg actgagagat
     1741 attttgacgc aacgtgaatt cgcaaacacc gagataataa taatagcgtt gaaagtcagt
     1801 tgcttgatac agattttcag aaatatcaga agattttagt acttgttcta acttccgata
     1861 atcacgtttt tggaaacaac tatccaacag ttcaaataat ttatcgtttg tccgagtagt
     1921 ttttcgagag agattcatca catgatcaat cgttacccct agccgttgac aaatctgcat
     1981 catcaccaat acattcggca gttcctcatt attttcgatc cgacttaata cactttgtga
     2041 acaaatatca tgcgaaagca ttttttgcgt cattttttgt tcttttcgaa tctctttaat
     2101 gatcgttcca aaggactcga ttaacgtttc cataagtatc ctccccaaaa tatgcgtatt
     2161 cgcattctat tcgtatttta ctttaggaag tcgcaaactt caagaaaaga cttgcaacta
     2221 aataatatac tttagttatt taagaaaact ccactagaaa gagagcctca gtgtgtttgt
     2281 ctgtggccct cctactgaaa aatttggttt ttaaaatcat ttttggcgat aggttgctag
     2341 gaattctctc attttcttag ctgtttgttt caaatcatcc attttaggaa gataaacgat
     2401 tcgaaaatga tctggctggt tccaattaaa tccaccacca tgtacaagta gaatatgatg
     2461 ttcatgtaaa aagtccaaaa cgaatttttc atcatccaaa atattgaatc gctttgtatc
     2521 aatttttggg aatatataaa aagcagcttt tggttttacg gctgaaagac caggaatatc
     2581 attgattgca ttatagatat attctctttg ttcatagatc cttccgcctg gcaggagcag
     2641 ctcatcgaca ctttgataac cgcctagcgc ggtttggata atttgctgag acaatacatt
     2701 ggaacacaaa cgcatggagg acaacatatt cagcccttct atatagcctt tgacgtgtga
     2761 cttatctcca cttaggacca tccagcctac tcgaaatcct gctacacgat gagatttgga
     2821 tagaccgttc agcgtaacaa cgaacaaatc aggcgctaat gtagcaatcg gaatatgttc
     2881 tagaccatcc atcactaagc gatcatagat ttcgtcggaa taaataatca ggttattttg
     2941 tcgagctact tcaacgattt cttctaataa ttcttttgga taaagtgccc cagtaggatt
     3001 attaggatta atgataacaa tagcttttgt ccgactcgtt atttttgatt tgatatcatc
     3061 aatatcagga taccattctg cctcttcatc gcaaatataa tgaacaggtg tgcctccagc
     3121 taatgcaata gaagccgtcc acaacggata gtccggcatt ggaaccagta cttcatctcc
     3181 attgtccagc aacccctgca tacacatcgt gatcaattcg ctcactccgt tgccggtgta
     3241 gatatcattg atcgtcacat tcggaaaatg tttcagttgg caatattgct caattgcttt
     3301 tctagcagaa aagatcccct tggaatctga gtagccttct gagtcacggg cattcatgat
     3361 caaatcacga atgacttcgt ttggtgcttc aaatccaaaa ggtgcgggat ttcccgtgtt
     3421 caattttaaa atactaatgc cctcttcttg catccgctcc gcttcttcta gaacgggacc
     3481 gcgaacatcg taactgacac cttctaattt gttggatttt tcaaattctc tcatcactta
     3541 gccaatccct catttcaaaa agttagaact ttccaaattt tttgttattt actatttcaa
     3601 tatcatactc catcctagaa aattttgcca cttatttagg aaaaacgtaa gtattaaaaa
     3661 aacacaaaca agcgttgaga acttaattgt catgatagtc attccataga ttcgctgccc
     3721 aatccattgc aattccacaa atgattccta gcataaaacc aagcaaaaaa cgtccgaatg
     3781 caagtccaat caatacacct aagatcattc ccagtcctga aaattctccg tcatatttct
     3841 ccatcttaat aagtcctccc atttttgagc ttgacaacta tgtaaaacct cgctatcatt
     3901 agtgtgttat tattacgcag atgtgttgga attggcagac aagcatgatt gagggtcatg
     3961 tgagcgttag ctcgtgtggg ttcgagtccc atcatctgca ctacaactcg tgaagttaat
     4021 tttgcttcac gagttttttt gtttgaacgt ttctttatgc cattatatac atatcactgt
     4081 atcctttaca aaaagaacgt acaatcatgt aaacagcctg aggtgagtat atgaaggtcg
     4141 gaaacaagct actcgtagaa acttgcaagt gttaaaacaa ttaatcgaaa aacgagtaaa
     4201 atccctcacc taatactaaa gcgagggatt ttttgtatat tatctgttta tcaccgttat
     4261 tataaaggta caaataccaa gcacggttaa tccaaattgc ataaattcat ttttttgtac
     4321 actcatgctt ttcattagct ctttaactgc cattagtact aagatggcga taacaacata
     4381 aagtatatag tacgtccgca ttccggaagc ccatactgtg ggagaaaatc ccataattaa
     4441 ccttgaacaa aatcccatta tcatcaaaat aactaaaaaa atagaagttt tcttattgtc
     4501 aaaacttaaa taaattccaa caattaaaca tagtaataat gccaagacta ctaaagtagc
     4561 tatccaagta cctggataaa aaagtgacag tttcgttcct aactctgtaa agagattatt
     4621 caggttacta ctactccaaa tcattgccct tttatttcca ttgacgtaag taaagctttg
     4681 acccattgta ttaccaaaat aaataatcag gtttaagaaa aacggtaatg cagtcaatat
     4741 acgcacataa tagttttgac atttcctata tgttagaagg aaaattaaga aaaatagcaa
     4801 taaaaataag atattcatgt ctaaaaaaac ggctttccaa atgatgaaat acctaaatct
     4861 aacttattaa gaaagttgaa atttttatat tcaggaaacc atttattaat ttcatgtgca
     4921 gcacgtaatg cattccctgg agttgtcaaa gagaaaatta attctgctaa gcttattatt
     4981 gaaaatactg ataacttata attatatcgt ccattgacaa tcaaatataa actaactata
     5041 cttgttagaa caaaaaaaca ggcgttgact tgttcttgat tagttaaaaa tatcaataaa
     5101 ggaatactta cccaatatat ttttctattt atttcttctc ctcttaagag ttgaaaaaac
     5161 ggataaaaag ttagtaaact aaatgctact ggccactgat agttcaaggt ggttgctctc
     5221 caaccggttt cccccattac tgtcaatggt attaaacagt atatagagca aaccaataat
     5281 aaatttttaa catttatttt ctcaaaaaca ta
//
LOCUS       DADGKS010000140         5309 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.145, whole genome shotgun sequence.
ACCESSION   DADGKS010000140 DADGKS010000000
VERSION     DADGKS010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5309
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.145"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            288..590
                     /locus_tag="JXV47_002869"
     CDS             288..590
                     /locus_tag="JXV47_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488843.1"
                     /translation="MDKKAAMQRIIELTYSEDWQNDKEAASEVMRLGRAMWADKSNKP
                     RPRKIAIWHGDKLLVIGTAEQLASLTGLHEKIVRKRARCGYTDAKKRTFRYVEESS"
     gene            587..748
                     /locus_tag="JXV47_002870"
     CDS             587..748
                     /locus_tag="JXV47_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAX1488844.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIHRLEE"
     gene            745..1050
                     /locus_tag="JXV47_002871"
     CDS             745..1050
                     /locus_tag="JXV47_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488845.1"
                     /translation="MSVDKKAAMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPK
                     RRTPRKIAIWHDDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
     gene            1050..1406
                     /locus_tag="JXV47_002872"
     CDS             1050..1406
                     /locus_tag="JXV47_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HAX1488846.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKTRSIQHGFI"
     gene            1366..1611
                     /locus_tag="JXV47_002873"
     CDS             1366..1611
                     /locus_tag="JXV47_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488847.1"
                     /translation="MIKKLVQFSMDLYDIESGATLSVESDHLIINFGGKRQIILWVVD
                     DVLFPEIVHDFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            1608..2027
                     /locus_tag="JXV47_002874"
     CDS             1608..2027
                     /locus_tag="JXV47_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein"
                     /protein_id="HAX1488848.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVTGNIYENSELLEEQR"
     gene            2024..2581
                     /locus_tag="JXV47_002875"
     CDS             2024..2581
                     /locus_tag="JXV47_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HAX1488849.1"
                     /translation="MNKQEAIKKLESIKAIGNDAIAACYNESINSGITLMKKIDEPQK
                     PVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLWAIKNADGNYLTKCALWGKDGVNYSFECNPSHRL
                     LFTDKATADAAALLVNGTVEEVVER"
     gene            2578..2874
                     /locus_tag="JXV47_002876"
     CDS             2578..2874
                     /locus_tag="JXV47_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488850.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKSKFKVGDMVRCEA
                     EEFVYPFRGYVKKILSNSAIIRIENTMKCDRSTAKHKHYLAVARLVDMEVIKSK"
     gene            2951..3364
                     /locus_tag="JXV47_002877"
     CDS             2951..3364
                     /locus_tag="JXV47_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HAX1488851.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIETERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGKIIAYK"
     gene            complement(3822..4097)
                     /locus_tag="JXV47_002878"
     CDS             complement(3822..4097)
                     /locus_tag="JXV47_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488852.1"
                     /translation="MYKPYMISYDLNNPGQKYDKVFEIIKEFGAYIKLQKSFWLVKTN
                     LNPNQMCEKLNTVLDNNDSLFICELQKNYQGRATEENWKFINEHIFS"
     gene            4551..4757
                     /locus_tag="JXV47_002879"
     CDS             4551..4757
                     /locus_tag="JXV47_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488853.1"
                     /translation="MLGQCFGNHARFDSLPATLNAYDGYDYRKKIVKKLYGATYGNVV
                     SVLSVHHQASVTVAEVEDAAVNGE"
     gene            4953..5120
                     /locus_tag="JXV47_002880"
     CDS             4953..5120
                     /locus_tag="JXV47_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAX1488854.1"
                     /translation="MYRPQYLEQKYEVITVHKGNGEKVYEYRRPIKSDTYKRKENNEV
                     IPLYGKRIAKH"
     gene            5146..>5309
                     /locus_tag="JXV47_002881"
     CDS             5146..>5309
                     /locus_tag="JXV47_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAX1488855.1"
                     /translation="MTEEFYRWLLQLTREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRV"
BASE COUNT         1887 a          820 c         1186 g         1416 t
ORIGIN      
        1 ctcagatact atttcgcact ttatatcgat acaacacaat taagaaattt agcatatacc
       61 aaattactat ttgttgattg tgttaaaggc ttgcaaaaac atcttaatga acttgagcag
      121 gtgtaatcag atggacctaa agacatttac agcacagatt gaactaatgc atcaagaagc
      181 tttaagacaa agtgtatcgt acgaagacaa gtggctcaac acgttccatg gcggacgtga
      241 gagcgcactt gatcaagtac tcaaattact gaaaggagaa tgtcgggatg gataagaaag
      301 cggcaatgca gcgaattatc gaattgactt attcagaaga ttggcaaaat gacaaagaag
      361 ctgcttcaga agtgatgagg cttggaagag cgatgtgggc agacaagagc aacaagccaa
      421 gaccacgaaa aatcgcaatt tggcacggtg acaaacttct agtgataggg acagctgaac
      481 agttagcaag tctcacaggc ttgcacgaga aaatcgtgag gaaaagagca aggtgtggct
      541 acacagacgc taagaagaga acgtttagat acgtggagga atcatcatga caacagaaga
      601 agtgattcaa atgcgtattc gaagccttca gcgtgagatt gacgatctgg aacgaacaaa
      661 ggcagtgatg gtcaatgaaa cggcgagaaa ggcaatcgat ttgcacatag agaatttaag
      721 aagggaaatc catcgattgg aggaatgagc gtggataaga aagcagcaat gaaaagaatt
      781 gctgaattaa ccaagtcaga atcttggcaa gaagacaaag aaatagttgc agaagtccaa
      841 aagctcggta aatcaatgtg gactgaaaag cccaaacgga gaacgccgag aaaaattgca
      901 atctggcatg atgaccgaat tttagtaaca ggtactgctg aacagttatc tgaaattact
      961 ggattaagca aaaacattat ctgggataga gctaggagct tatggattga ttcaaaagga
     1021 cgacagttta ggtatgtgga ggagagataa tggatctcat tacacaatac agtgacatca
     1081 tcctcaagaa aatcatgatg aagattcaga aagataaaaa atcaaaagaa cgagctgaat
     1141 tagttaagtt agaaatggct gaaacaggag caggagtgcg aagtagcagg cattggaaag
     1201 cagcagcaaa cattgaattt tattacaacg aaattcaaaa agggttcgat cagatgcgtg
     1261 agctggatcg gcaaacaaat tggagcaaga aacttcatca agatcgtttc aaatttgtag
     1321 agaagtataa agaaatatta gaagagtatt tgaggaggac agcaaatgat aaaaaaactc
     1381 gttcaattca gcatggattt atatgatatc gaatcaggag caacactatc tgtggaatcg
     1441 gaccatctaa tcataaattt tggtggaaag cgccagatta ttttgtgggt agttgatgat
     1501 gtactgtttc cagaaattgt tcatgatttc gaagaatcaa aagcggttga gtttgaaata
     1561 gtgaaaaaag taatggaatt gattgaaaaa tacgaggagg acagcgaatg ataccgaagt
     1621 ttagagcgtg ggataaacga aagaacgtaa tgagagatgt agccgtcttg cattttacta
     1681 aaaacggcaa aacaaacttt attgaatatt ggataaatcc taccgaattg aaatcatatc
     1741 acgtgcgaaa catcgacctc atgcaatcca caggaatgaa agataagaat ggtgtggata
     1801 tatttgaagg ggatatagta ttagtcagcg tgcgaaatgg cttcgattac ttagataata
     1861 aagtctgtat tgtcaaaaat tcaatagatt attccggatt agtttgtgcc actgttgatg
     1921 aagacttaga gtatcaaatt tttaacacag agctgtttga agaatacacg tacgaagtca
     1981 ccggaaatat atacgagaat agcgagttat tggaggaaca gcgatgaata aacaggaagc
     2041 aatcaaaaag ttagaaagta ttaaagcgat aggaaatgat gcaatagctg cttgctataa
     2101 cgagagtata aattcaggta ttacgttaat gaaaaaaata gacgaaccgc agaaaccagt
     2161 tattccacaa ctcgtggccg gttggcttga gaaatctacg gaccctttta caaaagctga
     2221 aaaaatagcg tatttaatca aatctaaaga tggtgattca tattatttct gtgattggtt
     2281 tgtacgagat ggcatagtga cgcaagagca aggagaagaa ttactcgctt gggcaacaag
     2341 acaatcatat gaaacactat tgagcctata caacggctac gaggttgaga aagagccgtt
     2401 atgggcaata aagaatgccg atggaaacta tcttactaaa tgtgctttat ggggaaaaga
     2461 tggagtaaat tatagttttg aatgcaatcc atctcatcga ttgcttttca ctgataaagc
     2521 aacagcggat gctgcagcat tgttggtgaa tggaacagtg gaagaggtgg tagaaagatg
     2581 aaactaaaag acggatttta cgctagcagt cacggtatcg gcggtttaat gctagatatg
     2641 ccgacaaaga accctaaaac acgcaagaaa tcaaaattca aagtcggtga catggtccgc
     2701 tgtgaagcag aagagttcgt ttatccgttc agaggatacg ttaaaaagat actgtcaaac
     2761 tcagcaatca ttcgtattga aaatacaatg aagtgtgatc gttcgactgc aaaacacaag
     2821 cattatttag ctgtagcgag attagttgac atggaagtaa tcaagagcaa ataaaaaaag
     2881 ccggatcgct ccgactgatt caataaatcc aacacattta ttatatcaca taaaggagcg
     2941 gtttgacttg atgcaattgt tacgagaggt agatttcaaa cagacaagat gtaatgcgag
     3001 agatgtgctg aagaactttc ggcgtttgga gcggatggca ggtcgctctt tgatagatat
     3061 taagtcgccg attataacgg atatgccgaa ggcaccgaag catggcaata aggcagaaga
     3121 cgcgattatt cagatgatgg atatagaaac ggagagagat gcgattctag cggctttgat
     3181 ggctcttagt ctgattagtc gtcagatact ctactacagc ttctgtgtgc cagatagctt
     3241 ctcaaactac agaattagcc gtgaagtggg ttattcagaa agaagtatac aacggatgaa
     3301 gtcggaagct ctaatagagt ttgcagaagc atataaacac ggaaaaataa ttgcttataa
     3361 ataatttggc ggttttttgg cggaatgatg gcggttttta gacatttacc agtgttatta
     3421 tggtagtgtc gaaagattag gaaacaggat cgacaaaata aacgaaggga ggcaatctcc
     3481 ctcatcgttt taaacttctt cttagataga cagcaactaa ttatgaagaa aaggatgtga
     3541 attcaactcc tcctaaattc ttcatcggtt gctgtttatt ttgattagac agcagcactc
     3601 acaaaactaa acatgttctt gtcgtctttc aactgctgct gtctattaat ttatgtattg
     3661 gagggaagaa aaatgaaatt atcagtagaa ggcactccag aagaaataca agaattgctc
     3721 caagctattg gtagtagcaa ggagcaaaag gtaagtgttt ctaattcaga tattgacggt
     3781 atttgcaatt gtttaaacag agaaaaaata tctaatcctt actaagagaa aatatgttcg
     3841 ttaatgaatt tccaattttc ctctgtagct ctaccttgat aatttttttg cagttcacag
     3901 atgaataagg aatcgttatt atcaagtact gtatttaatt tttcacacat ttgatttgga
     3961 ttcaaattag ttttaactaa ccaaaaagat ttttgtagct ttatatatgc cccaaattct
     4021 tttattattt caaatacttt atcatacttt tgccctgggt tattaagatc ataactaatc
     4081 atgtagggtt tatacatgtt gtcttgcaca tccttgtttt atatttcagc ggaccactcg
     4141 ctgataaata aaattatacg cttagtattt attttcacaa tattaattta tcgtaataac
     4201 ttttgagtaa atagaacaaa aaacctgcac tagtttccgc tagtacaggc agtgactata
     4261 tcggttgata atctagcata tattaaaaat aattgcaaga aaagaaattt atagtggttt
     4321 ataccaaatt atcaaagcaa tgttattttg ttgctgtcta ttgtttttta attattcaca
     4381 cgataactaa aggtgggtga agagaaatga ttccattaat aatttcaatt tttgcgctct
     4441 gtcttaatgt ctatatgatt ggatttaaaa atgggcaaaa taaaaaatag tagcagccaa
     4501 gaataatttt atagtgtcac tgtggcggaa agggtagacg ctaagcatgt gtgctaggtc
     4561 aatgcttcgg caaccatgca aggttcgatt ccttgccagc gacattaaat gcctatgacg
     4621 gttacgacta ccgaaaaaag atcgttaaga agctatacgg tgctacgtac ggcaatgtag
     4681 taagtgtgct atctgtacac caccaagctt cggtcactgt ggcggaagta gaagacgcag
     4741 cggtaaatgg cgagtagcct cgtgagagcc tggtaagttc tcgtgagtgg tgcaatccca
     4801 ctccagcgac tttaagcaac cgaggcatcg gcggtttaaa aatatagggg tgcgcaattt
     4861 cgtacgcgtt ttgtgcatcg tgcaagttac tattacatat tagatcactc tttgagtggt
     4921 ctttttattt ttgcacaaag gaggaaacaa caatgtatag accacaatac ttagaacaga
     4981 agtatgaagt aatcactgtt cataaaggta atggcgaaaa agtatatgag tatagaagac
     5041 caataaagag cgatacatat aaacgaaagg aaaacaatga agttattcca ttgtatggca
     5101 aaagaatagc taagcattaa ataagattgc gaaaggagac ggaacatgac cgaggaattc
     5161 tatagatggc tattacagtt gacaagagaa gatcgtttgg ttaagttcta tcagtctcct
     5221 aaatggcgca ggcttagaga gaaagcgatg aaacgagatc actatgaatg ccaagagtgt
     5281 agaagactag gtaagtatca tagagtaga
//
LOCUS       DADGKS010000141         5264 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.146, whole genome shotgun sequence.
ACCESSION   DADGKS010000141 DADGKS010000000
VERSION     DADGKS010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5264
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.146"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(1..412)
                     /locus_tag="JXV47_002882"
                     /pseudo
     CDS             complement(1..412)
                     /locus_tag="JXV47_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(614..1009)
                     /locus_tag="JXV47_002883"
     CDS             complement(614..1009)
                     /locus_tag="JXV47_002883"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HAX1488856.1"
                     /translation="MKVTMLKGKIHRATVEQAELDYVGSITVDMNLLEAAGIYEYEKV
                     QIVDVNNGNRFETYTIAGERGTGMICLNGAAARCVSTGDKIILMAYCELNENEVKDHR
                     PKVVFVDDNNKVERVTSYEKHGRLSDIIL"
     gene            complement(1019..1867)
                     /locus_tag="JXV47_002884"
     CDS             complement(1019..1867)
                     /locus_tag="JXV47_002884"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HAX1488857.1"
                     /translation="MVIFKTVNDVRSQVKEWKKQGLKVGLVPTMGYLHEGHESLIRKA
                     SKENDKVVVSIFVNPTQFGKNEDLGSYPRDLERDIEVCTRGRATAIFNPEVEEMYCDN
                     ASTFVNITGLTEGLCGASRPIHFRGVCTVVSKLFNIIPADRAYFGEKDAQQLAVIKRM
                     VRDLNIDIDVVGCPIIREEDGLAKSSRNTYLSLEERSSATILNKSLTLAKEALNNGER
                     DSLKIIEIISKNINTYNLAKIDYVEVVDSLSLQRVNYIEKSVLVAIAVFIGKTRLIDN
                     FTFELQ"
     gene            complement(1882..2709)
                     /gene="panB"
                     /locus_tag="JXV47_002885"
     CDS             complement(1882..2709)
                     /gene="panB"
                     /locus_tag="JXV47_002885"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HAX1488858.1"
                     /translation="MKNTAVTFKESKLRNEKLTMLTAYDYSTAKIIDEAGINGILVGD
                     SLGMVCLGHEDTLSVTMEDMIHHTRAVTRGAKNTLVVADMPFMSYQTSVYDSVVNAGR
                     LIKEGRAQVVKLEGGIEVCDKIEAIVKASIPVMAHIGLTPQSVNAFGGFKVQGKDKEA
                     AKELIRAAKAVEKAGAFAVVLECVPTKLAELISKEISIPTIGIGAGAGCDGQILVYQD
                     MLGMYSDFTPKFVKKYANLSEEMNKAFTKYIEEVKDGVFPGPEHGFKISDDVLEKLY"
     gene            complement(2721..3581)
                     /locus_tag="JXV47_002886"
     CDS             complement(2721..3581)
                     /locus_tag="JXV47_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002384409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HAX1488859.1"
                     /translation="MEVIIMNVGFIGAGKVGCSFGKYFQEHKIQVTGFYSKSEDSSLA
                     ASNFTSSKQYLNLRELVDENDTIFITTPDGQIQEVWQEIKNYQIKNKLICHCSGAISS
                     DIFSNIQDYGAYGYSVHPMFSISDKYNSYKKLKKSFITIEGDEKYAKFLCDFFKKLGN
                     STVIVSKENKSLYHAASVVSSNLVLGLINTSVTYLIQCGFTEKMAIEALYPLIEFNIR
                     NIKEKGIIESLTGPVERCDISTIKGHCEVLSDEDRALYMLLSKNVLEIAMLKNINRDY
                     SELEKYLGES"
     gene            3819..4988
                     /locus_tag="JXV47_002887"
     CDS             3819..4988
                     /locus_tag="JXV47_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAX1488860.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGRKEICEDFKLV
                     YQANSKEEALDHIDFMTRKWKKQYPRVVNLLLNPALLTFYNFPHAIRRTIYSTNLIEG
                     FNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQDTLESMI"
BASE COUNT         1663 a          988 c          678 g         1935 t
ORIGIN      
        1 acgatctctt ctaagtcgga ctcattttcg atcggtttcg cttgataata gtaggtctga
       61 cgagaaatat ttagaatttt gcacatcgct gatatggaat atttatgctt gttggcatca
      121 attacttgtc ttttcgtccg aatatcagcg ccgcttgctt taaaatatca ttctccattt
      181 cgagttgctt atttttcttt cttagtgcga tcaattctgc ttgttctggt gttaagttgt
      241 ctcttttttt gaatgagccc gttgattgtg cttgcttcat ccatttatcg aaagaagaag
      301 gcgtaagctc atactctcga ataatttctg cgcgaggctt accagcgaga tagagatcga
      361 cgatttgttg tttgaattct tttgaatagg ttcttcgttg acgtcttgac atgaaaaatc
      421 ctccagtgtg ttttttatta ttctacacac cttatttttt ctgtctagtc tagtgtagcc
      481 gattcacata aaatggactt tgtctacagt ctgtatcttc tctttttgtg tctactttat
      541 tgacatctat ccaattagta atcaataaat atttcaataa tagtctagct atatataaat
      601 aacattacaa aacctaaaga attatatctg ataaccttcc atgtttttca tatgatgtta
      661 ctctttcaac tttattatta tcatcgacaa aaacaacctt aggtctatga tccttaacct
      721 cattttcatt taattcacaa tatgccatta aaattatttt atctccagtt gatacacatc
      781 tagctgcagc tccattcaag caaatcatcc ctgttcctct ctctccagct attgtataag
      841 tttcaaatct atttccatta ttaacatcaa ctatttgtac tttttcatat tcatatattc
      901 ctgctgcttc taataaattc atatcaacag taatacttcc tacataatct aactcagctt
      961 gttcaactgt agctctatgt atttttcctt ttaacattgt aactttcatt atagccccct
     1021 attgtaattc aaatgtaaaa ttatctatta atcttgtttt tcctataaat actgctattg
     1081 caactaaaac tgatttttca atataattta ctctttgtaa tgataaagaa tcaacaactt
     1141 ctacataatc aatctttgcc aaattataag tatttatatt tttacttatt atctcaatta
     1201 tttttaagct gtctctctct ccattattta aagcttcctt agctaaagtt aaagatttat
     1261 ttaaaatagt agctgaagat ctttcctcta aacttaagta tgtgtttcta gaacttttag
     1321 ctagtccatc ctcttccctt ataattggac accctacaac gtctatatca atattaaggt
     1381 ccctaaccat tcttttaatt acagctaact gttgtgcatc cttttctcca aaataagctc
     1441 tatctgctgg tattatgtta aataatttac ttacaacagt gcaaacccct ctaaaatgta
     1501 ttggcctact agctccacat aaaccttctg ttaatccagt tatattaaca aaagtacttg
     1561 cattgtcaca atacatctct tcaacttcag gattaaatat tgctgttgct ctacctcttg
     1621 tgcatacttc tatatctctt tctaagtctc ttggataact acctaaatct tcatttttcc
     1681 caaactgagt tggatttaca aagatactta caacaacttt atcattttct tttgatgctt
     1741 ttctaattaa actttcatga ccttcatgta aatatcccat agtaggaact aatcctacct
     1801 ttaagccttg ttttttccac tcttttactt gacttctaac atcattcact gttttaaata
     1861 taaccatatt tcttgaccct tttaatataa tttttctaaa acatcatcac ttattttaaa
     1921 cccatgttct ggacctggaa aaactccatc ttttacttcc tctatatatt ttgtaaatgc
     1981 tttattcatc tcttctgata aattagcata tttcttcaca aatttagggg taaaatcact
     2041 atacatcccc aacatatctt gatatacaag aatttgtcca tcacaccctg cacctgctcc
     2101 aataccaatt gtaggtattg atatctcttt agaaattaac tctgcaagct tagttggaac
     2161 acattctaac actacagcga atgctcctgc tttttctaca gctttagcag ctcttattaa
     2221 ttctttagca gcttccttgt cctttccttg taccttaaat cctccaaatg cattaacaga
     2281 ttgaggtgtt aaacctatat gcgccataac aggtatagaa gcctttacta tagcctctat
     2341 tttatcgcat acttctatcc ctccttctaa tttaacaacc tgagctcgtc cttcttttat
     2401 taatcttcct gcattaacta ctgaatcata tactgaagtt tgataagaca taaatggcat
     2461 atctgcaaca actaaagtgt tcttagctcc tcttgtaact gctctagtat gatgaatcat
     2521 gtcttccatt gttactgaaa gtgtatcttc atgtcctaga cataccatac caagagaatc
     2581 tcctactaat attccattta tcccagcttc atcaattatt tttgctgttg aatagtcata
     2641 agctgtaagc attgttaatt tttcatttct taatttagat tctttaaatg taactgctgt
     2701 atttttcatc tatttctctc ctaactctct cctaaatact tttctaattc actataatct
     2761 ctattaatat tttttaacat agctatctct aatacatttt ttgataatag catatataaa
     2821 gctctgtctt catctgataa aacttcacag tgacctttaa ttgttgaaat atcacaacgt
     2881 tcaactggcc ctgtcaaact ttctataatt cctttttctt ttatatttct aatattaaat
     2941 tcaattaatg gatataaagc ttcaattgcc attttttcag taaatccaca ttgaattaga
     3001 tatgtaacgc ttgtattaat aagtcctagc acaaggttac tagatactac tgatgcggca
     3061 tgataaagag atttattctc cttagataca attacagtac tattacctaa ctttttgaag
     3121 aaatcacata aaaactttgc atatttttca tcgccttcaa ttgttataaa agattttttt
     3181 aattttttgt atgaattata tttatctgat attgaaaaca taggatggac agaatagcca
     3241 taagcaccat agtcctgtat atttgaaaag atatctgaag atattgcacc actgcaatgg
     3301 cagattaatt tgtttttgat ttgataattt ttaatttctt gccatacctc ctgaatttga
     3361 ccatcaggag tcgtaatgaa aatagtatca ttttcatcta ctaattctct taagtttaaa
     3421 tattgtttac tagatgtaaa attcgaagct gctaatgacg agtcttcgct tttactataa
     3481 aatcctgtta cttgtatttt atgttcctgg aaatacttcc cgaatgaaca acctaccttg
     3541 ccggctccaa taaaaccaac gttcataatt atcacctcca taaagaagtg agactacaag
     3601 tcccattctt acgatatgag cttaaaaata aaaattaaat caaatataca gtatgttttt
     3661 ttcaaatatc atccatagtt aatttatcat aatatcccat attttaaaat aaaagatagc
     3721 gtaaaatatt ttgtgtaaat agaaatttag ggtagaaaaa aaagtccatt ctgtaaaatt
     3781 aaagttacca cacagaaatt ttataggagg actttctcat gactaaattt actatagaaa
     3841 ttatgcaaac actactcaat aaaggggatt tagatgaatt atttcaggat catttagagc
     3901 gagcgattaa ttcacttcta caagcagagc taactgcttt tttagattac gaaaaatatg
     3961 atcgaaatgg attcaattca ggaaattccc gtaacgggaa ttattcacgt acatttaaaa
     4021 cagaatatgg cgagttgaat ttaactattc ctagagatcg gaatggcgaa ttttctcaac
     4081 aaacactacc agcatataag cgaaccaatg attcattaga aacgaccatt atccaattat
     4141 ttcaaaaagg cattactatg gctgaaatct ccaaattaat tgaaaaaatg tatggtcacc
     4201 actatacgcc acaaacaatc tccaacatga gtaaattggt ggctgaagat gttttagctt
     4261 ttaaagaaag aacgttagaa gccaattatt ccgttatatt tatggatgcg acgcatatcc
     4321 ctgtgaagcg acagactgtt tcgaaggaag cagtgtatat tacgattggt attcgtttgg
     4381 atggaaccaa agaagttctt gggtttacta ttgccccaac tgagtctgct tatatttgga
     4441 aagaagttct tcaagatctt agaaaacgtg ggttagaaga agttttatta gtagtgacag
     4501 acggattaag ctgtattgaa gaaagtatcc atagtgtgta tccgaatgcc caatttcaac
     4561 aatgttgtgt gcatgtatct agaaatatcg ctcataaagt tcgtgttcga ggtcgaaaag
     4621 aaatttgtga ggatttcaaa ttggtttacc aagcgaattc aaaagaagag gcattggatc
     4681 acatcgactt tatgactagg aaatggaaaa agcagtatcc aagagtcgtc aatttactct
     4741 tgaatcctgc cctattaacc ttttataatt tccctcacgc catcagacga acaatttatt
     4801 cgacgaacct gattgaaggc tttaataagc agctaaaacg atatactcga agaaaagaac
     4861 aattccctaa tgaagaatct ctagagagat tcttcatttc tcaatttaat caatataacc
     4921 aaaaattttt aggtagaatt cacaagggat ttaaagaaat tcaggataca ttagagtcga
     4981 tgatttaact gtaattaaca gaatggattt tccatttaca cataattctt gacgctacca
     5041 taatctaaat aaccatcata ttcatctact acttatataa ttgagtttta ttaaactttt
     5101 taagtttcta ttctatcaaa tatttaaaca atctctgcat ccgaaaagac tacctcgtat
     5161 agttttacta acaatatttt tattagcgtg ttcaaatcct gatttcttgt atcaattatt
     5221 ttctgttcac tttcaataag aaaaaagtct ttacttccat ggat
//
LOCUS       DADGKS010000142         5207 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.147, whole genome shotgun sequence.
ACCESSION   DADGKS010000142 DADGKS010000000
VERSION     DADGKS010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5207
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.147"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            34..1368
                     /locus_tag="JXV47_002888"
     CDS             34..1368
                     /locus_tag="JXV47_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488861.1"
                     /translation="MDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYYAY
                     GLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFVVV
                     NLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDITT
                     YTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLLQF
                     PWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVIQS
                     KHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKAAD
                     NNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIEIT
                     TKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            1355..2989
                     /locus_tag="JXV47_002889"
     CDS             1355..2989
                     /locus_tag="JXV47_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488862.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            3164..3997
                     /gene="msrA"
                     /locus_tag="JXV47_002890"
     CDS             3164..3997
                     /gene="msrA"
                     /locus_tag="JXV47_002890"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAX1488863.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQGERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            4077..5066
                     /locus_tag="JXV47_002891"
     CDS             4077..5066
                     /locus_tag="JXV47_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-glyceraldehyde 3-phosphate reductase"
                     /protein_id="HAX1488864.1"
                     /translation="MYIADSARYEKMEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQ
                     REILRGAFDMGITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMW
                     EGPYGEWGSRKSIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGK
                     ALYIGISNYNGEDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGA
                     ITFSPLAQGLLTNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQS
                     LAQMALAWNLRQKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
BASE COUNT         1825 a          806 c          951 g         1625 t
ORIGIN      
        1 agtttttatt atggagaaaa gttttttaaa aagatagatg ctgctttttt atttagttgt
       61 ttatatactt ttgcaactta tcgaacagtt gatatctatt atcgatccgc aattgcagaa
      121 gcaatcgctc ttacgattat cccagctgtt ttatattatg cttatggatt gatattcaat
      181 agagaaaaaa aagtcatcgc tttatctgtc agtataagtc tacttgtgta tactcatgtc
      241 ttaactacac tattgtgtag tgcattgatt gcttgtatga ttatagttcg tttgttttta
      301 agcaagcaaa taaaaaacga tataaaattt gtggtcgtga atttagtaaa ggctgttttt
      361 ttgacttgtg cattaactag ctatttttgg tatcctatgt tgcagcagat gaattatcaa
      421 gaaatacaca gtcccttcaa aacagatttg cagctagaag cactttctat ttcagatagt
      481 atcattcaag cgttaaataa cgatattaca acatacacta tggggttatt aggattggtt
      541 gcgttgattt ttcctttatt catactgaaa gaaatggaga aaaaagaaaa aatcatctat
      601 gttggcgtag tttctacatg ggtatgcgta actaatttat ttccatggtt tttgtttcaa
      661 aaaacaccga taagcttgct ccagtttcct tggcgtatct taggtatcca aatctttttt
      721 tcttcaatga tcataacgct tgtttttatg aaaaagacta tgaataaaaa atattcatgg
      781 ttaatcattg gcgctactgt ggtgtttcta ctcgtcacgt ctatagcagc aaaagaaaat
      841 tacgcaaaag ttatccaatc aaaacacggt catattgtta tcaatgaaga aacactccca
      901 cgttatacaa catcagatat gggaggatta tacgattacg ccccaacaga agcgataaaa
      961 gaaaggcctc acttagaaaa acatgaagta aaagtaggag aatcgtggga aaaagggaag
     1021 tataaagctg cagataataa cattacttac acagtggcaa gcaacaaaaa gcaaaaagtg
     1081 acagtaccag tatatgctta tttaggtaca caggtaaaag taaacggtaa agtcgtaaat
     1141 gactcttata aaaaacatgg cttagtgaat gtggatgtaa atgctggaga aaataagata
     1201 gaaattacaa caaaatatac tccaactgct ctcatggctt tatggatcag tattctgact
     1261 tattgtttag tggtgtattc aagttttaaa cgatttgcac ctaataagtt gaaagattct
     1321 cgatatgtga ctaaaaagga gataaacaag aagaatgaaa ataaataaaa aagtagtaat
     1381 attgagtgga ttaattatag ttagtagtat atattctttc atctttttca aaaatacaca
     1441 gagtatttat accactggag atctttcttt tcacttatct cgaatcaagg ggttatcgac
     1501 tatttttacc agtccgatta attatgagac attcaattat actggatatg gtgtaaatta
     1561 tttttatccc tttctgactt tttttccagc tgtaatgtta tattggatga caaaaaattt
     1621 gattgtaagc tatattattt acgtttggtt attgaacttg tgtacaacac tcgtagctta
     1681 tcattatggc gagcggtttt taaaacaaaa aaaagcggca tttttattta gttgtctcta
     1741 tattttctct gcttatcgga cagtagacat ctactatcgt tccgcaattg ccgaagctat
     1801 cgcaataaca cttgttatcc ctgtattatt ttatgcttat caaatcatct ctggaaaaga
     1861 agaaaagtat ccgtctgtaa agctagcatt gagtatgagt ttgctagtgt acagccatgt
     1921 actatcaaca ttaatgagta cagcattaat tatcattttt atttttattc gtttggtttc
     1981 taaaggtttc aagaatgcag attttattgc tatatttaaa aaattattta gtgcggcagg
     2041 aatgacattg gttctgacga gtgctttttg gtatccgatg tttgaacaaa tgctctacca
     2101 aaaaatcaac aaacctagcg tgacaaattt atatgctcat gcatctaatg tgttcgatag
     2161 tctgactgaa gctatgaaca acgacttaac tacttactca atgggactag ttggtctgtt
     2221 atctttatgt attcccctga ttttatttaa aaaattaaca aacatagaaa aaaagattta
     2281 ttatggtacg tgtttgactt ggctagctac aactagtttg gtgccatggt atcttctgca
     2341 aaatacgcca gccaaattgt tacaatttcc ttggcggatc ttaagcttgc aaataatatt
     2401 ctcttctctg atattaacga tgatattttt caaaaataga agatacaata agacaagaga
     2461 actattttat ttatttatga ctgttttgtt attaatcact ttaactgttt ctagtaaaaa
     2521 aaatttcaat caaaaaataa tttctcagcc gggacatatt gttgtaaaca aagaaacagt
     2581 agaggcgtat accactaaag gaatggatta ttttttatat gattattctc ctatcgcttc
     2641 attggagaat aaggagcata taataaaaca cgaagcaaag attggcagtc aatgggtaaa
     2701 ccttccttat aaaacaactg gtagttctat catatataga gtaactaatg agaagagcca
     2761 agtaatcaca cttcctgtat atgcttattt aggaacgaat gtagaaataa atcatcaacc
     2821 tgtaaaggag caggtgaatg ctaatggatt ggtacaaata agcggagtca aaggagttgc
     2881 tgatattaaa gtaagcacaa gttatacagt aacgactatt atttcttatc ttgttacatt
     2941 aactgcatat ttatgtttat tttttaaaat agttttccat aaaaggtaaa ttaacttttc
     3001 atttataaaa taaattgatt aaaaaggaga atctgtcgat aaggattctc tcttttttat
     3061 acgaaaaatc tgtaggggga tgaagtaatc gcttatttcc tcactttatg ataaattaca
     3121 gctaaagtca ctagcttgtc ttcttcggaa aggaggagaa tctatggatg aggaacaaat
     3181 attcattcaa acactttata atctgatttt gaatccgaat acacgagatt gggaacgaaa
     3241 agtattgatt cagacaaaga atgacataag agaaaatata tccgttaaag aacagttatc
     3301 aaaactagaa gcaacactac gtccattagc tatccgaatg aatctgacgc ctgatgtaat
     3361 ggacttttat ttattgatta cggaaggatt tgataaggag caaaaatatg acttttccaa
     3421 gcatgccatg caagatgctg actatcaaga acgtgcagta tttgcagggg gatgtttctg
     3481 gtgtatggtc gagccgtttg aatcgaaaaa agggatccta tctgttttgt caggatacac
     3541 gggcggacat gttgaaaaac caaattatga tcaagtaagt ggtggttaca caggtcatgt
     3601 ggaagctgtg gagatcattt atgacacaag agaaataagt tatagcgagt tgctgacaat
     3661 ctattggcaa attactgatc ccacagatac atttggacaa tttcaagata gagggaagca
     3721 atatcgtcca gtgatttttt atcaaggcga acgacaaaaa gaattagcgg aacaatcaaa
     3781 acagaaacta gacagttcag gaactttcca ccaaccaatc gtcacaaaaa tcgaaccagc
     3841 cggtacgttt tggccagcag aaaactatca tcagcaattt tacaaaaaac aaccgaaacg
     3901 ttataaaaaa atccagcaag cacgtaatca atttctgatc tatcaacgag taaaaaacaa
     3961 atggcaaaaa aatatacgaa aaaatcattt tgattaactc cttttcttta aaatgtagta
     4021 aactaaaaat agaaaaaaga aagcgtttta aaaagatttg atgaggagga gaaaaattgt
     4081 atattgcaga tagtgcacgt tatgaaaaaa tggaatatcg taaatccggt cattcaggtt
     4141 tgaaattacc gattttatct ctcggattat ggcaaaattt tggtgattat gatcctatcc
     4201 ataatcaaag agagatttta agaggcgcat tcgacatggg aattacccat ttcgaccttg
     4261 cgaataatta tggaggccct gctggagctg cagagaaaaa ctttgggcgt atttttagag
     4321 aagattttca agcctaccgt gatgaactga ttatttctag caaagcaggt tatcatatgt
     4381 gggaagggcc atatggggaa tggggctctc gtaaatccat catttcaagt tgtgaccaaa
     4441 gtctccaaag aatggggcta gattatgttg acatcttcta tcatcatcgc ccagaccctg
     4501 atacaccttt ggaagaaaca gcagaagctt tgatgcaact tgtaagacaa ggaaaagcat
     4561 tatatattgg tatatccaac tataatggag aagatacaaa aaaaatgact gaaattttaa
     4621 aaagaaagga agcaccgttc attattcatc agatgcgcta caatatgttt tctcgtgcac
     4681 tactagaaga cgatctatct ccagtattag aagaagaagg gctaggggca atcacgttca
     4741 gtccgcttgc tcaagggttg ctgacaaatc gttatctaca tggtattcct gaagattcta
     4801 gagcacatcg taaggaaata ccattccttt cagaagaaca agttggatca actctggaaa
     4861 aaatcaaagc actgcaaaca atcgccgtat cacgaggaca atcattagcg caaatggccc
     4921 ttgcatggaa tttgcgacaa aaatctgtta caagtgtact ggtcggagca agtcggttaa
     4981 gtcagttaca agaaagtgtt cgaatgatgg ataatttaga tttctcacca gaagaagaat
     5041 tgagaatcga ccaaattcta gaatagaaac gatgtaatca aactttttat ccatatatta
     5101 aaaaaaacaa aagatgacat caagaatcga atgaagatcg tctgttattg aacatcatat
     5161 tttttgtcgt tcaaaataaa aatgatcgaa ggctaggagt gaatttt
//
LOCUS       DADGKS010000143         5197 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.148, whole genome shotgun sequence.
ACCESSION   DADGKS010000143 DADGKS010000000
VERSION     DADGKS010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5197
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.148"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            23..694
                     /locus_tag="JXV47_002892"
     CDS             23..694
                     /locus_tag="JXV47_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAX1488865.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            753..1193
                     /locus_tag="JXV47_002893"
     CDS             753..1193
                     /locus_tag="JXV47_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488866.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1205..1873
                     /locus_tag="JXV47_002894"
     CDS             1205..1873
                     /locus_tag="JXV47_002894"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAX1488867.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1937..2560
                     /locus_tag="JXV47_002895"
     CDS             1937..2560
                     /locus_tag="JXV47_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HAX1488868.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2616..3002
                     /locus_tag="JXV47_002896"
     CDS             2616..3002
                     /locus_tag="JXV47_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HAX1488869.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3215..4606
                     /locus_tag="JXV47_002897"
     CDS             3215..4606
                     /locus_tag="JXV47_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HAX1488870.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
BASE COUNT         1726 a          861 c         1095 g         1515 t
ORIGIN      
        1 tgatgaaaaa agggggagaa aaatgaattt tttagttgtt ttaaaagata ctctgattga
       61 gcgatctaca tttctatatg ttcaattgca ggaaaataaa acattgctgc atttttcacc
      121 agagttccat ctagaggggc taacattagg agaaatctat caagcagaag ggctgtcggc
      181 tgttttgcac ttttttaagg tagaattgga attaccagta aaagattata tcgagctttc
      241 tcttgaatct tgggatcgag cagtggttga actgtttcca gaaggtttaa tgatcgatac
      301 aaacgatggg aagatccatc tgactgcagc agaactgcaa aaacaaatgc gttatcaaat
      361 agatgacgaa aattcttttt ctatttttag acgtcagcaa aagattctaa aaagcttttt
      421 aaaagtgatc agtaaaaaac ggaatctgat caaaacgaca cagctgttga aaaaatatcc
      481 aggtctgctt cacacgtcta ttcaatttcc tcaattgatt acgatgatcc atcgttttat
      541 acgtatgcaa cagctaccat ctaagaagct gtttcttcca ttgacggaca catttcgagt
      601 agtcaacaga gaagataaaa agaaagtgat tgtgattgac tttaccagaa atcggaatgt
      661 ccttcaccaa gttgcaatgg aaaaggccaa ttaaggcttt ttctttttgg atttttttgt
      721 cataataaat attagatgat ggaggagata atatgatgca aacatggtta gaaaggctaa
      781 tacgatttca gcagaactat cacaaactta tgcagggaag atatgcgaaa tttgatcagt
      841 tgaatcgcgg tctattgatc gctgcgcttg tctttagttt gctaagtcgt tggttgccct
      901 atagaatcgg acaattgttg ttcatcgtct ttttcggatg gatgatattt cgtttcctat
      961 caaaaaaaat ctaccccaga ctaaatgaga atcaacgtta tttgaaatat cttgatagag
     1021 tcaaagaaaa atatcatcag ataaaaaaca aaaagcaagt caaaatggat cgaaaaagtt
     1081 atactttttt tgagtgcccg aattgtcatc aaaagcagcg tgcacctaaa ggaaaaggac
     1141 gaatacgtgt gacatgcaaa acatgtggta taaaattcga aacgaatgtt taagggagaa
     1201 aagaatgaaa ttagtattat tacgtcatgg cgaaagcgaa gcaaattttg aaaattactg
     1261 gacaggatgg ctagatgtcg ccttaacaga aaaaggaaaa gaacaagcag cagttgccgg
     1321 tcaaaaaatg cttgaagccg gacttcaatt cgatgccgtt tatacctctg ttttgaaacg
     1381 tgcgattctt accggacaag tcgcactaga agaaatgggt cagttatggc ttcctataat
     1441 aaaaacatgg cgtctaaatg aacggcatta tggggatctt gtgggtaaaa acaaagataa
     1501 gatgaaagaa atatacggaa aagatcaagt aaaaacatgg cgcagaggat atacggaagt
     1561 tccgccgtta accgcagaaa atagatttga ccgcagatat gatcacttgg atccgcattt
     1621 gatcccatac ggagaaagtc tggaaatgac agtgaatcgg atcattccct tatggcaaga
     1681 tcatctagca ccaaaactaa aagatcggca agatttacta gttgtgggtc atggtaatag
     1741 catccgagca ctgacaaaat atttagaaga tgttcctgaa gatcaaatgg atacgatcga
     1801 tatcccaaat gcacaaccaa tccagtatac attagcagat gatttgacaa ttctggacaa
     1861 aaaaatactt taaagaacac ctttatctaa aagtgagaga tagaaaaaag aagcaaagga
     1921 atggaacaaa aggaacatga aaaattatat atgggacttt gatggtacat tgtttgatac
     1981 gtatcccgca atggtagatg gtgcatggca agcactaaaa gattttggta tcagtatgga
     2041 caaaaaagaa atctacttca aaatgaaaaa gtattctact agttatttga tcaatgaatc
     2101 aaacttgaat gccagagagt ttaatgaatt atttcaccga tatgaaaaag aaagtacgga
     2161 agtttcccgt ccatttccag aaacgaaaca agtactggaa atgctaaaag acaacggcgg
     2221 tcgtcatttc atcctgaccc accgtttgac agaatcaaca tggggcctgt taaaagaaca
     2281 tcgattggca catctgattg aggaagtagt agggatcgat caggactttc ctcgtaaacc
     2341 tgatccagca tctttaaatt atttgatcga tacttttcat ttagaaagaa cagacacgat
     2401 gatgatcggc gatcgtcgtt tagatatcga agcagggaaa aatgcaggag tcgctacttg
     2461 tctttacgac atcgatcatt ttctgggtga gatcccggca gattatgtgg taggaaatct
     2521 gaatgaaatc cttaccttgc agagcatcat taaaaagtag tatccccttt caaaggagat
     2581 atgttataat tttcataaag gagtgataaa attatatgga aatcagaaga caaaaagaag
     2641 ttgtagaagc atttcattat gatatgagat tgccgaacca agaagtagaa acagatttga
     2701 aagtaggctt ctcgccttta aaagaaacga tcgaaaacta tccgaaagaa catagcatcg
     2761 taggagcacg cttagagttc cgtttagtgt ttgatacata tgttttatct ggaagtgtga
     2821 gtcagatcaa tcatatcctc aatcggaaaa ttgaaggtca aaatgatgtc acacaagaag
     2881 aagtggacga gctagtagca ccgttattcg atatcgtacg ccgaatgtct tatgaggtga
     2941 cagagatcgc cttagatcag cctggggtaa aattgaattt tcaatcagaa aaacaagaat
     3001 agacagtaaa aacatacctg cgatagatta aagctatcac aggtatgttt ttttattact
     3061 aattgtaagc aaaaagaatg tcatttcgat aaaaatcgtc taaaatataa aagtcactga
     3121 aaaaaatttt ttcaggagga tggttgaaga atcattctcg ggaaccttta cttccttcga
     3181 tggacttgtc attaataata tgaggaggag aaaaatgaca acactcatca cagttttagt
     3241 ggttctagtt tttgcggcat tattatatgt gttctatcgt atgcaaaagc gccatacaaa
     3301 attttcaaca cgcgtcttta cagcattagg agttggtatc gtctttggcg gtctgcttca
     3361 attgatcttt ggtgtagacg acaaagtcgt tactcaatca atggaatgga tcgggattgt
     3421 aggtcaagga tatgtatcat tcttgcaaat gctagttatg cctttagtgt ttatttcgat
     3481 cattggtgca ttcacaaaaa tgaaagtttc tgaaaagcta gggaaaatta gtgcgactgt
     3541 attgacttct ttacttggaa caacagctat tgcagcattg atcggaattg gttcaacaat
     3601 gctgttcgga ctccaaggag ctaaattcac acaaggagct gcagaaacag cacgaatctc
     3661 tgaactggca acacgtcagg aaacagttga aaacttatcg attccacagc agattttatc
     3721 ctttatccct aaaaacgttt ttgctgattt agcaggtagt cgtgcaacaa gtacgattgg
     3781 agtcgttatt ttcgcggcat ttgtcggaat cgcttatcta ggcgtgaaaa gaaaagcgcc
     3841 aaaagaagca gcattctttt cagatttagt cgacagtctg tataaaatca ttatgcggat
     3901 cgtgacgctt gttttgcgtt tgacacctta tggagtattt gctttgatga caaacgtttt
     3961 ggcaacaagt gattttgcag ctatcgtcaa tttaggtaaa tttgtcgttg cttcttacgt
     4021 agcattgctt gctgttttga ttgtccactc actgattttg attggtgcaa aagtcaatcc
     4081 aatcaactat ttcaaaaaag cctttccggt attgagcttt gcgtttactt cacgttcaag
     4141 tgctggagct ttgccattga atatcgagac tcagacaaaa gctttaggag tagatgatgc
     4201 aacagctaat ttctcagcaa gttttggttt gtctattgga caaaacggct gtgctggcgt
     4261 ttatccagct atgttggcaa cgatcgtcgc accagcagct ggagtgaatg tctttagttt
     4321 ggaatttatt ttgatgcttg tggcaattgt aacaatcagt tcttttggtg tagctggagt
     4381 cggtgggggc gcaacatttg cttcactgat cgttttaggg gcaatgaact tgccagtagc
     4441 aatcgttggg ttagttatct ctgttgaacc attaatcgat atggcacgta cagcagtaaa
     4501 cgtcagcggt agcatggtag ctggtatcgt gacaagtgca cgcatcaaag atttagatcg
     4561 cgatgtcatc aatgatgatt ctaaagtgat cgatgtgaat gcatagtcaa aaagaggttg
     4621 tgatagaagt ggtcagcttt aagaaataag aagaagtttc ctaaaaatag tttctcaaat
     4681 ttttgtgaaa tttcggctta tttccgagaa gctacttctg aaacaccgtg aataagaggt
     4741 tgtgaaaaag ctgccctgca tcaagtaata agaacagcca aacaaaaata gttcctcata
     4801 ttttacgttt ggttgagctt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
     4861 aggtcgtgag cctgccgttt cactctgagt cacaaagagc aatttcaaaa aatagcttct
     4921 catgtttgtt gaatattgtg tcttgtgacc gaggagttgt caggagaaca ccgtttacca
     4981 gaggttgtga cttgttttta gtcacgacct ctttttttat ttattccata taaatacaca
     5041 ttatttattc cgaaaagtga aagcgcaaat aacaaaaaca accaacttat ttattattaa
     5101 agaaaagcgt atttaagtag gacgattctg ttgagagctt tcgtagattt tcccattttc
     5161 ctatggtaaa ctgacaaagt tgagaatgtt agaacag
//
LOCUS       DADGKS010000144         5091 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.149, whole genome shotgun sequence.
ACCESSION   DADGKS010000144 DADGKS010000000
VERSION     DADGKS010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5091
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.149"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(1..125)
                     /locus_tag="JXV47_002898"
                     /pseudo
     CDS             complement(1..125)
                     /locus_tag="JXV47_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(387..1718)
                     /locus_tag="JXV47_002899"
     CDS             complement(387..1718)
                     /locus_tag="JXV47_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1488871.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(1867..2580)
                     /locus_tag="JXV47_002900"
     CDS             complement(1867..2580)
                     /locus_tag="JXV47_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAX1488872.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            2755..4179
                     /locus_tag="JXV47_002901"
     CDS             2755..4179
                     /locus_tag="JXV47_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015508962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAX1488873.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            4478..>5091
                     /locus_tag="JXV47_002902"
     CDS             4478..>5091
                     /locus_tag="JXV47_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HAX1488874.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYV"
BASE COUNT         1668 a          905 c          835 g         1683 t
ORIGIN      
        1 tagattttcc ggcattgttg atagatttta tgatactttt ctacattttg taagagaggt
       61 tccactgcat ctgtatattg gataaaattc tgacaacaac tttcaggtgt gtcgaaccac
      121 tctaatcttt aaagataaat attaaaataa cgattaataa tattaacagt ctttattttt
      181 caccaccaaa aacctatctt tgcatatact aaatagacgt atatacacag ataggtttgt
      241 cttgtgaaaa ataatgatta tccttaccaa aaaatgtttg tttttctaca tgttcgtact
      301 tatcaaaaaa tatgatcctt attgaaatta ctggctattt atattccaac gacttcttgt
      361 gttaattttt gttatctcat agtaaattat gtttcatttt cacttaattt agttgtcacg
      421 tgttcgtcaa ttcgtaaaaa cggtaaatat ataaacacac ttgcggctat aattaatatt
      481 tgtaaaacag ctgctcgcca gtctccggct gttgctaaaa atcccgatat aactggtggc
      541 gtagtccaag gaatttgcac tactacatga ttaattaatc ccacagcagt tgcaaaatat
      601 gctactgtca aagaaaaaat cggtgcaagc acaaagggaa taatcagact gatattaaat
      661 acaataggca atccaaaaat aataggttcg cttatattga atatagcggg agttaccgat
      721 aatttagcaa agtccttata atcttttcta cgactgaaga taaatattgc aatcaataaa
      781 gcaatcgtat ttcccgatcc acccattacc gcaaaggtat ctttaaaggc catattgata
      841 atatgtggaa tttgctcttt gtttgcataa gctgccatat tttcttgcat attctgaatc
      901 aaaaacggat ctaacaatga acctgatatt actgcttgat ggataccaaa tccaaaaaat
      961 agattagcaa tagatgtaat taacaaaaat cctggtaaac cagttgtaat tttacttaat
     1021 ggctctgtaa ctatcgtggt aattagctta tttatatcca tattaaacaa ttgaatgatt
     1081 ataaatgaca ataaagcaaa cgaggtaatc gtaataatga ttgggattaa tacattaaaa
     1141 gactttaaaa cagcgggagg aatatttccg gatagctgaa tctgtagttt cttattatta
     1201 gaaagtttaa taaataattc tgtagccgct aatccaacaa atatacctac aaacattcct
     1261 gaagctcctg tataggatat aggtatcaca cccgtcactt caacagcttt atccgcattt
     1321 tcaggagtaa acatcatctg cataggtgtt aatacaacaa atgtcgaaat agcaactaat
     1381 accgctgcaa tatgatttgt ataatttctg cttgcacaca tatgataaga tactgctgct
     1441 acaactaata atgtagttat gcttaatgta ccattggcaa ttgaagtacc aatttgttgt
     1501 aacgtggtca atgtactagt atcgacaatt tcccccatga atcctgttgg ttctaagatc
     1561 actgaattaa taagtgtcac aaatcctgct aacatcataa atggcataaa tgtagcaaac
     1621 gcatctcgca aagttcttaa atggatctga ttccccaact tagtcgcaac tataccaaat
     1681 ttttcaaata caatgtcctt cctgctactt ttgcccatat tttttctcct ttatgcttat
     1741 tgtaatcgat tactttttcc acccaaataa tacatcactt atcaaaaaaa gtaaatactt
     1801 ttaattaaat atatatatct tttttagtat aaaaaaataa gctctgaaaa aataattttc
     1861 ccgagcttat ttttcaacaa aaacagcttc aaaaacaaag tcttgatata aatgtctcga
     1921 taccgaatac tcgaaaggtt taccagacga tagagcaaca actttgtcta tctcaatcat
     1981 aaattcacct ggatctattt ttaatatttt tgcgtcaaat tcattcgcag tatctccttt
     2041 gatacgtatg tgcgaagtct ttatttccag acccagttca tttgtgatat aagcatatac
     2101 agatttcttt aaatgttttg gttccaagcc tggtatgact gctaatggca tgaatgtttg
     2161 ctcaatcgag tatggttgac aatcaataaa acggcttcgt acaatattat atacatagtc
     2221 ttttacactg atacttaatt tatcagctac ttttttcgat ggaagttcaa ttgagaaagt
     2281 atggatttct gaatctacgt gttcttcacc aaccacgcta aacaaacctt cgtttggacc
     2341 aagaactcgt gagttatcaa ttggtgttct gacgacttca gtcccatacc cacttctact
     2401 tcgcaaaact ccttcggaaa caagtaagtc tacgcctttc tttactgtta acttgcttgt
     2461 atgataaata actgccaatt catctcctgt aggaagtttc tcaccaattt tatactctcc
     2521 atttacaatt tttttcttta tatctaagta aatttccata tacttcgcaa tttttttcaa
     2581 tggtgaccct ccaatcaaaa acatatcttc atctatactt taacataaat aaaccgataa
     2641 aatccacatc aaaattatac acacaataaa aaagatatat atatttaaac aaaactattt
     2701 actttaattt gtaagcggtg ttatcattaa gtggaaacag gaggtaaaaa aattatgaca
     2761 actatgaaaa agctaacttt tccagatgat ttttggtggg gttccgcttg gtcagctgag
     2821 caagcagaag gaaaaggaga aacaggaaaa gcagagacta tctgggatcg ctggtttaaa
     2881 gaacaacctt accggtttta tcaacgaatc gattcctcta ttacaaccga tcacatccat
     2941 caatataaag aagatataga actaatgaaa aaaactgggc ataactcctt tcgcgtttct
     3001 atttcttggg cacgaatgtt tccaaatggc ggtaccggaa aagtaaatcc caaagccatt
     3061 tctttctatc gaaaattatt ttccgaaatg aataataacg gaatcaaagt atttgccaac
     3121 ttatatcatt ttgacatgcc tgctactctt caagataaag gaggatggga atcacgtgaa
     3181 gtagttgatg cttatgttca ttacgctgaa acttgtttta aagaatttgg tgacttagtt
     3241 tgtcattggt ttaccttcaa tgaaccactt gggcctattt taggtactta tcttgaagat
     3301 tttcattatc caaacctcat tgactttaaa cgcggagcgc aagcagcatt cttcactata
     3361 cttgcacacg caaaagcaat acaagtattt aaagaactag ctcttcctag taaaataggc
     3421 gttattctaa atttgagtcc tacttttcct cgtagtcaaa atcctgctga tgtgaaagca
     3481 gcagaaatcg ctgatttatt ttatacgcgg agctttttag atcctatggt taaagggaat
     3541 ttttctaaaa agcttatcct gttattacaa gaatataatc agcttcctga agattatacg
     3601 aaagaagatc ttgtatgtat ctacgaaaat accgctcaaa ttcttggact aaactattac
     3661 gagccacgtc gcgtcaaatc tcgttcttct atggtggata catctagtcc atttttacca
     3721 gagtggtttt tcgaaccaca tatcatgcct ggacgacgaa tgaacgaata ccggggatgg
     3781 gaaatttacg aaaaaggaat ttatgatttg tgcatggata tcaagaacca ttatggaaac
     3841 atcgaagcat ttatctcgga gaacggaatg ggcgttgcgg atgaagaacg tttcatggat
     3901 gatacagggc aaataattga tgattatcgg attgagtata tcaaagatca tcttgcttac
     3961 ttatggaagg caataaatga aggatgtaac attaaggggt atcatctttg gacatttatt
     4021 gattgctggt catggatcaa cgcctataaa aaccgatatg ggctggtttc actcgacctt
     4081 actactcaaa aaagaacaat taaaaaaagt ggcgaatttt acaagcaatt aagtgataca
     4141 aatggattta gatacgatgt agacttgtta gttgaataat attctaaaat tccacttgaa
     4201 gtgaacacat tagaaaacaa gaataatgag aaataccaat aacaaatact ttttcttcat
     4261 acttcattta tacttgtcag tataagagac tgtgacaaat gtagtgatcc tcagaagtta
     4321 ggtctggaaa tctaacttga gaagattttt ttaaactacg tccagtcttt tttatttgtt
     4381 taaaattgaa gttgacaagt cttcattaaa aatttagaat attcacaagt ttgacgacaa
     4441 ttatgaaaat ttatgtcgtg ctaaaggagt tttgttattg gatgaaaagt tagatataaa
     4501 aactgcgatc aaagacacgt tacctaccgt ttttggttat atcggtattg gacttgcatt
     4561 tggtatcgtt gggaaagctg ccgggtttca tccgctggtc gtcacgttga tgtccctgct
     4621 gatctatgct ggttctgccc aatttatcac ggtcagcatg cttgctagcc atagtccact
     4681 gctctccatc gttctctcga cctttctagt caattcccga atgattctga tgagtatgac
     4741 gattgctcct tatttcaaga aaaatcggct gcttcaaaat ctgctgattg gcacattgct
     4801 gacagatgaa agtttcgcac tgggaatgaa taaattgaac tatactggac aaaagttaaa
     4861 ctttcgttgg atgaatacag ctaattggat ttcttatttg acgtgggtgg gttcttctct
     4921 tgttggcgca cttttaggga attttattac tgatccgaaa aagtttggtt tggatttcgc
     4981 catcgtcgct atgtttatcg ggttacttta tcttcaagtc atttctgata gaaacacctc
     5041 taaacgatta cagttgatcc tgattggtct cactttgatt ctggtatatg t
//
LOCUS       DADGKS010000145         5088 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.150, whole genome shotgun sequence.
ACCESSION   DADGKS010000145 DADGKS010000000
VERSION     DADGKS010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5088
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.150"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            202..1389
                     /locus_tag="JXV47_002903"
     CDS             202..1389
                     /locus_tag="JXV47_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAX1488875.1"
                     /translation="MYFLGIDIGKRTHVASIMNEEGKVLLKGFSFPNTTEGAESLIER
                     MVDYSGAPSDFVIGMEATGHYWLSIFSYLHESDYLIHVVNPLQTDGWRKGTEIRKRKN
                     DIIDSVLIADLMRYGSFVETVLSDENVFSLKQLSRYRTYLVGTASDFKRKIIAVLDQV
                     FPEYATIFTKQGVFGKASKELLLAFSAPIDLENISSETLAQYLAELSRNRIKAEKADQ
                     LKQAASNSFGVKFAQEAFTFQLRSMIEQLKFIESQIKETEREIKHIMDTLNSVILTIP
                     GIGPINGATILGEIGDIQKFSNPKKLVAYAGIDASVTQSGQYEATHNVMSKRGSPYLR
                     KALFSAALVASQCDPVFSAFYQKKVSEGKHHLTALGAVSRKLCYVIHAILTKNEPYII
                     VSD"
     gene            complement(1481..2221)
                     /locus_tag="JXV47_002904"
     CDS             complement(1481..2221)
                     /locus_tag="JXV47_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAX1488876.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGETNYIESSKN"
     gene            2909..3067
                     /locus_tag="JXV47_002905"
     CDS             2909..3067
                     /locus_tag="JXV47_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1488877.1"
                     /translation="MNKKQTCEFLGIDNNTLDKWIRIYNFPVIRIDGIVRFDIEDIKD
                     FMNTFKTI"
     gene            3139..4365
                     /locus_tag="JXV47_002906"
     CDS             3139..4365
                     /locus_tag="JXV47_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAX1488878.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGITSEKYQKVFPTRQLAIKA
                     ENAMKRKIETVLREENANSLELKGKIKFKEFYESKWLPRYELGQTTRSKRAPSYVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQCITAPKKIALEERRIREGNQALSSEELIAWIEAVNTDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFEKQTVRLKHALDKYQKKKFTKGRKDTV
                     IQVPEIVMALLSKWKSVQAEQLLRLKINQTPDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPELAHLSPHKLRHTYATIARQGGANMNQISSALTHSDISTTRIYVNTPDVV
                     DKTVFEAFQRGLNKCD"
     gene            complement(4454..4846)
                     /gene="rpsI"
                     /locus_tag="JXV47_002907"
     CDS             complement(4454..4846)
                     /gene="rpsI"
                     /locus_tag="JXV47_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAX1488879.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(4862..>5088)
                     /locus_tag="JXV47_002908"
     CDS             complement(4862..>5088)
                     /locus_tag="JXV47_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HAX1488880.1"
                     /translation="IYYRHSNYPGGLKSITAGELRAKNSRRLIETSVKGMLPKNTLGR
                     KQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
BASE COUNT         1698 a          893 c          874 g         1623 t
ORIGIN      
        1 ttggattgag aggctaagcc gttcccccct tgggccattg aacccgcact cgagagactg
       61 gctcctctct ctgataagtg gattgcgtat gagttagatg ttgaaagtcc ttactttact
      121 ccgtatctcg tacaaggtag tgacgctttt cagttgagtg gatttcaatc caaaattctt
      181 tttttgaaag gtcagatata catgtacttt ttaggcattg atatcggtaa acgcactcac
      241 gttgcttcta tcatgaacga ggaaggaaag gtattactaa aaggtttttc atttcctaac
      301 accactgaag gagcagagtc attaattgag cgaatggtcg actattccgg agcacccagt
      361 gactttgtta tagggatgga agccacgggg cactattggc tgtccatctt ttcatacctt
      421 cacgaatcag attatttgat tcacgttgtg aatccccttc aaacagacgg atggcgtaaa
      481 ggtacagaaa tacggaaacg aaaaaacgat attattgatt ctgttttgat tgctgactta
      541 atgcgctatg gctcatttgt cgaaacggtc ttatccgatg aaaatgtttt ttctttgaaa
      601 caactttctc gttaccgaac ttatttagta ggtacagcga gcgacttcaa aagaaaaatt
      661 atagccgtat tggatcaagt ctttccagaa tacgcgacga tttttaccaa gcagggcgtt
      721 ttcggaaaag cttctaaaga gttattgctg gcgtttagtg ccccgatcga cttagaaaac
      781 atttcctcag aaactttggc ccaatactta gctgagttaa gcaggaaccg aatcaaggca
      841 gaaaaagcgg accaattgaa gcaagcagct tctaactcct ttggagtaaa atttgctcaa
      901 gaagcgttca ccttccaact acgttcaatg attgaacaat taaaattcat tgaaagccaa
      961 ataaaggaaa cggaaagaga aatcaagcac ataatggaca ctttaaattc tgttattctc
     1021 acaattcctg gaattggtcc tataaacggt gcgactattc ttggtgagat cggagatatt
     1081 caaaaatttt ctaacccgaa aaaactcgtt gcttacgctg ggatagacgc ttccgtgaca
     1141 caatcagggc aatatgaggc aacgcataat gttatgagta aacgagggtc tccatatttg
     1201 cgaaaagcct tgttttcggc ggctttagta gcttctcaat gtgatcctgt ttttagtgcg
     1261 ttttaccaga aaaaagtttc cgaaggaaaa catcatctaa ctgccttagg tgcggtttct
     1321 cgtaagcttt gttacgtgat tcatgctatt ttgactaaaa acgagcctta tataattgtt
     1381 tctgattagc tattgaacat tcaaaaaaac taatggtaag aagcttattt gttgtaccct
     1441 tttttcggaa ttatctgtta taaaatattt tttgatttgg ctaattttta cttgactcta
     1501 tatagttagt ctctccaata aatatagtat ctccataggc tttttttaaa ttctcttcat
     1561 taaatacaga ttctacactt ccgtgagcaa ttagatttcg attcaaaaga ataatattat
     1621 caaaatactt ctttaccttg cttaaatcat gatgcacaat tagcactgtt tttccctgat
     1681 gtttcaattc ttttaacgta tccataatta ttcgttcact aactaagtct atccctacaa
     1741 atggttcatc taaaaatatg aaatccgcat tttgagcaag acatcttgct aaaagtacac
     1801 gttgaaattg tcctccagat aattctccta tttgatgatt agaatatttt cccatatcga
     1861 ccttttccaa agcctttgaa actctttgcc attctgcatt tttaattctt tgaaaaactt
     1921 tcattccggc atatgttccc atagatacac attcttttac ttttattgga aaagtaaaat
     1981 caatatcagc tttttgctct acatatgcaa tcttcaccag ttttttattg atatcttcat
     2041 tattaatgga gacctctccc tgatgaggga taatatttaa cattgcttta agcaatgtag
     2101 attttccagc accatttgga ccaataatac ctgttaaagc accttcttgt atttttaaag
     2161 aaatctcgtt caatgctaaa aaatcgttat aacaaacatt aagctttttc acttctaaca
     2221 taactttctc cttctaaatg ataatgatta tcacgatcat atggtataca aaaattatat
     2281 tttagtcaac cctaaatttt ataatttaga tttttttctg ttgctgaaga ttagaatgac
     2341 aaaactattt gaaactacgc gtatagtaag tagctttcaa aatatataaa aaaggagcgt
     2401 tctcaaatga gaacatgctc ctaaaactac tttattggcg tatggaaaaa ttatacttaa
     2461 agtggatagc gggttgaata agttgataag catcaaaaca tttataaaaa ttattcaaga
     2521 ctatgtctgt tccatataca aatatgaaaa tcagtaaact ccatttaact tttttcgtag
     2581 tgtgtctttt tatacatgtt tatcgttatt aatagtgaat aggaaaaaac ctatttttga
     2641 tcattgacaa ttaaatacaa tttttgaata acgatccctg ctattcgagc tagaaactca
     2701 agtacgccat gacctgatta gcgacaaata cttagagatt tctttttgtt ctgggaaaac
     2761 aaaatgccat gacaatagca gcaaataatg atacttccgt aaggctcgcc gtaaactggg
     2821 gagaggtgaa attcctatgt gcttacccaa agcaattcaa aaattctaat cttttttagg
     2881 agatgatttt ataaaattga gagtctactt gaataaaaaa caaacctgtg agtttctagg
     2941 aattgataat aatactttag ataagtggat tcgtatatat aattttccag taatcagaat
     3001 tgacggtata gttcgctttg acatagagga tatcaaagat tttatgaata catttaaaac
     3061 aatttgaaaa tttcttctcg ccgcatatac taagaatagc gaaatatact gccttacttt
     3121 ttaagggagt gaggaatttt gcctacaaaa ctttcaaatg ggaaatataa aactaatctg
     3181 aggtatccaa aaaaattcag agaaatcact ggaattacat cagaaaagta tcaaaaagta
     3241 tttccaacta ggcaattggc tattaaagcc gaaaatgcaa tgaaaaggaa aattgaaaca
     3301 gttttaagag aggagaatgc aaattcacta gaattaaaag gaaaaataaa atttaaggaa
     3361 ttctatgaat caaaatggct tcctagatat gaactaggtc agactactag atcaaaaaga
     3421 gctccaagtt acgtaacaat tagtaatact aaagatatat tccgattgca catccttcca
     3481 atgtttggtg agtatgcaat gaactatcta aattcaaata ctgagataat atcagatgaa
     3541 ttaacaaaaa aatcgaaaga atacgcaaat ataaaaatta tcaaaggata tgtccgttct
     3601 atgtttgata ttgcagaaat actaaattat attgaattta accgaactac caaaattatt
     3661 caatgtatca ctgcacctaa aaaaattgct ttagaagaaa gaaggatacg ggaaggtaat
     3721 caagcattat cgtcagaaga gcttattgct tggatagaag cagtaaacac tgacttgaat
     3781 aatcacttgc ttactcttca tgactatact cttttcatgc ttaccctata tcttggtgat
     3841 agaaaaagtg agacgtatgc tttgcaatgg aaatatatcg actttgagaa acaaacggtt
     3901 cgccttaaac atgctttgga taaatatcaa aaaaagaaat ttacaaaagg tcgaaaggat
     3961 accgtaattc aagtacccga aattgtaatg gcattactaa gcaaatggaa atcagtgcaa
     4021 gctgagcaat tgttgagatt aaaaattaat caaacaccag atcagtatct ctttacctat
     4081 actaaaccat ccggagaagt aaattgccct gttcacgctg attacctaaa ctatcgaatc
     4141 aattcaatta aaagacgaca tcctgaattg gctcatttat ctccacataa gcttcgtcat
     4201 acctatgcaa ctatagctag acaaggcgga gcaaatatga atcaaatatc tagtgcttta
     4261 acacactcag atatttctac aacgagaata tacgtaaata caccagatgt agtagataaa
     4321 actgtttttg aagcctttca gagaggattg aataaatgtg attagtatgt gttcttaaat
     4381 gtgttcttaa acaagaaaaa gacacttttc aaacaattga aaagtgcctt gaaacattga
     4441 tatataaata atattaacgt ttagagaatt gagatgcttt acgagccttt ttgagacctg
     4501 gttttttacg ttcgaccata cgtgcgtcac gagtaagtaa gccagcacgt ttaagagcta
     4561 aacggaagtc aggatcaact tctagcaatg cacgagcgat accatgacgg atagctcctg
     4621 attgtccagc gtatcctccg ccgtttacgt taacaaatac gtcatatgcg ccttttgttt
     4681 cagtaacagc gaaaggttga ttgattactt cacgcaagtc agcatgtgga atgtattctt
     4741 caacatcttt tttatttaca gtaattttgc cagttcctgg tactagacgt acgcgagcaa
     4801 ctgcgttttt acgacggcct gtgccgatat attgaacttg tgccaatgaa attccctcct
     4861 attagattaa gtttgtgatg tctaaaactt ctggttgttg tgctgcatgt ggatgttctg
     4921 ctccaccgta tacgttcaat tttgtaaatt gtttgcggcc taaagtgttt ttaggaagca
     4981 taccttttac agaagtttcg atcaaacgac gagaattttt agcacgcaat tcgccagcag
     5041 tgattgattt caatcctcct gggtagttgc tgtgacggta ataaattt
//
LOCUS       DADGKS010000146         5087 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.151, whole genome shotgun sequence.
ACCESSION   DADGKS010000146 DADGKS010000000
VERSION     DADGKS010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5087
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.151"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(47..871)
                     /gene="iolB"
                     /locus_tag="JXV47_002909"
     CDS             complement(47..871)
                     /gene="iolB"
                     /locus_tag="JXV47_002909"
                     /EC_number="5.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-deoxy-glucuronate isomerase"
                     /protein_id="HAX1488881.1"
                     /translation="MEKTLKHQPLNKELAPGVKQIQNIRQSNSALSYIEFQILELEKG
                     ASYKETGSQQEVCIVILTGKIKVKAADTWYEDLGTRESVFEKIPTDSIYLPAEHSFEL
                     VATTDNVRLALCYSPAKKALPISVIRAEDNTVEERGLYQNKRLVHNILPDNVDTASSL
                     LVVEVYTEGGNFSSYPPHKHDQENLPHESFLEETYYHELDPEQGFVFQRVYTEDRSLD
                     ETMTVEHQNVVEVPKGYHPVGVPDGYTSYYLNVMAGPERIWKFHNEKKHEWILQRK"
     gene            complement(910..2826)
                     /gene="iolD"
                     /locus_tag="JXV47_002910"
     CDS             complement(910..2826)
                     /gene="iolD"
                     /locus_tag="JXV47_002910"
                     /EC_number="3.7.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002397168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3D-(3,5/4)-trihydroxycyclohexane-1,2-dione
                     acylhydrolase (decyclizing)"
                     /protein_id="HAX1488882.1"
                     /translation="MEKTVCLTTAQALLKFLNQQYISIDGKETPYVEGIFHVYGHGNV
                     LGIGQALELEPGHLKSYSGKNEQGMAHAATAFARQNLRKKIFAVSTSVGPGAANLLTA
                     AGTAFANNIPVLFLPADTFATRQPDPVLQQLEHASSVAFSTNDAFQAVSRYWDRINRP
                     EQLMSALLRAFEVMTNPATMGPATICLPQDVEAEAYAYPEEFFKKRVHYIDRRIPTAR
                     ELAEASQRIKASKRPVIIVGGGCKYSEAGEILEQISRDCQIPLVETHAGKSTVSWDFK
                     NNLGGMGILGTSAANKAVQQADLIIGIGTRYTDFTSASKSIFNFEQAKMMNINVSRQQ
                     AAKLEAFQVVGDAKATLEQLAPMIEGYQTAYGEKIDELKEEWISERNRLKAAHFKRKD
                     FTPEIKDHFSQEILNEYADALATNLTQTEVFIHLNDFVDEDAIVIGSAGSLPGDMQRL
                     WNPVKENTYHLEYGYSCMGYEIAGAMGVRMARPEQEVYALVGDGSFLMLHSELVSSLQ
                     YDKKINIVLFDNSGFGCINNLQMDNGGASQGTEFRNTKDEIMNIDYAKVAEGYGAKTY
                     RVSSIAELQAAVEDAKKQTRSTLIEIKVLPKTMTEGYDGSWWNVGISEVSGKAAMQEA
                     YKAKQAKLATIRKY"
     gene            complement(2837..3871)
                     /gene="iolC"
                     /locus_tag="JXV47_002911"
     CDS             complement(2837..3871)
                     /gene="iolC"
                     /locus_tag="JXV47_002911"
                     /EC_number="2.7.1.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018593001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-2-deoxygluconokinase"
                     /protein_id="HAX1488883.1"
                     /translation="MSYIKFDQSKEFDLLLLGRVAIDFNPAYNDQVKEEFKPLKKVHM
                     FEKFVGGSPANIAVGVTKHGMKAGFIGTVSDDQFGEYVIDYFNEQGIDTSQISKAQHG
                     EKLGLTFTEMLSSKESNILMYRNQAADLQLSVEDIDEDYLKRSKALLISGTALAESPS
                     REAVIKAVMLAKRNNVKIIFDIDYRAYNWKNNDDISIYYSMIAKESDIIMGSREEFDL
                     TEKLIQPNMSDNESAAFWHSCGAEIVVIKHGMKGSTAYTADQQQFSIKPFPVEARKGF
                     GGGDGYGSGFLYGLFEGWEIIDCLEFGSAEASMMVKSNNCSDSLPTTQEVKDFITLEK
                     EIYGEMIARI"
     gene            complement(4028..5044)
                     /locus_tag="JXV47_002912"
     CDS             complement(4028..5044)
                     /locus_tag="JXV47_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016633586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAX1488884.1"
                     /translation="MAGTIKEIAEKAGVSRGTVDRALNDRGRINPEVAERIRAIAKEM
                     NYVPKKKKVIKETTLKLGIVTQLAKSSFMIPIRSGLESIIGDLKKRNIDCFLEEVDGV
                     DEAAQLQALDRLVELGVKGIAIMPVDSDGIREKINQLTDQGILIITFNSDILGTNRQC
                     FVGMDNFKSGKTAAGLLGMLTKGKGKVLAITGYFGNSVNSLRVAGFVEELKESFPELE
                     LTGVQSSFDSSAEVEKILSNTLENYSNLDGVVVFSGGQAGIARALEKIDESKRPFVII
                     YDLTKNNIEMLKNDQVDFLIDQDGFVQGYRSLLMLANQLQNNKTVTKDALFTDIIIKT
                     KYNI"
BASE COUNT         1337 a         1270 c          909 g         1571 t
ORIGIN      
        1 acctaactaa acctaactaa actttatgta tctaacagct taataactac ttgcgctgca
       61 agatccattc gtgtttcttt tcattgtgga atttccaaat tcgctcaggt cccgccatca
      121 catttaaata gtaggaagta tacccgtcag gtaccccaac tggatgatag cccttaggaa
      181 cttcgacgac attttgatgc tctaccgtca tcgtttcatc tagtgaacga tcttccgtgt
      241 agacccgctg gaaaacaaat ccctgctctg gatcaagctc atggtaataa gtttcctcta
      301 aaaaagactc atgtggcaga ttctcttgat cgtgcttatg aggaggatag ctggaaaaat
      361 taccgccctc ggtataaact tcgacgacca gcaggctgct ggcagtatcg acattatccg
      421 gtaaaatgtt gtgaacaagt cgtttattct gatagagtcc acgttcttcg acggtattat
      481 cctccgcgcg aatcacactt atcggcaaag cttttttcgc tggtgaatag caaagcgcca
      541 atcggacatt gtctgtagtt gccacaagtt caaacgaatg ctccgccgga agataaatac
      601 tgtcggttgg aattttttca aaaacagatt ctcgtgttcc taaatcttca taccaagtgt
      661 ctgctgcttt aaccttaatt tttccagtca aaatgacgat acagacctcc tgttgactgc
      721 cggtttcctt gtaagaagct cccttttcca gctccaaaat ctgaaattcg atataactca
      781 aagcagaatt agactgccga atattttgga tttgttttac tccaggtgcc agttctttgt
      841 ttaatggttg atgcttcaat gtcttttcca atcaatccac tccttatttt caatcacaaa
      901 aagcaatatt taatactttc tgatagtggc aagtttcgct tgtttggctt tgtaagcctc
      961 ctgcatggct gctttacccg atacctctga gataccgacg ttccaccagc tgccgtcgta
     1021 gccttctgtc atggttttag gaagtacctt tatctcaatc aacgtcgatc gcgtttgctt
     1081 cttcgcatcc tcgaccgctg cttgtaattc tgcaatcgag cttacacgat acgtttttgc
     1141 accatagcct tcagcaactt tggcgtaatc gatgttcatg atctcgtcct tggtatttct
     1201 gaattcggtt ccttggctag ctccgccatt atccatctgt aaattattga tacagccgaa
     1261 accagaatta tcgaaaagta caatgttgat ttttttatca tattgcaaac tagaaaccag
     1321 ctcgctatgc aacatcaaga aactgccatc gcctactaag gcatagacct cttgttctgg
     1381 tcgagccatt cttacgccca tcgcaccagc gatttcatag cccatacaag aataaccgta
     1441 ttccaaatga taggtattct ccttcacagg gttccataag cgctgcatat cccccggcaa
     1501 tgaaccggct gaaccgatca cgatcgcatc ctcatcaaca aaatcattta aatgaatgaa
     1561 gacctctgtt tgcgtcaaat tcgtagccaa cgcatcagca tattcattca agatttcttg
     1621 agaaaaatga tctttgattt ctggcgtaaa atctttacgc ttaaaatgcg cggcttttaa
     1681 ccgatttcgc tcactgatcc attcttcctt cagttcatcg atcttctcgc cataggcggt
     1741 ttggtaacct tcgatcattg gggcaagctg ctccaaggtc gctttcgcat caccaaccac
     1801 ttgaaaggct tccagcttag cggcctgttg tctgcttacg ttaatattca tcattttcgc
     1861 ttgttcaaaa ttaaaaatac ttttagaagc tgaggtaaaa tcagtgtagc gtgtgccgat
     1921 ccctatgatc agatccgctt gctgcacagc tttattagca gccgaagttc ccaaaatccc
     1981 cattccgccg agattgtttt taaaatccca cgaaacagtc gatttacctg cgtgcgtttc
     2041 aactagcgga atctgacaat ctcttgagat ttgctcaaga atctcaccag cctccgaata
     2101 tttgcagccg cctcctacga tgatgacagg tcgtttactg gcctttattc gttgactcgc
     2161 ttcagcaagc tcacgagcgg tcggaatcct gcgatcaata taatgtactc tttttttgaa
     2221 aaattcctcc ggataggcat aggcttctgc ctccacgtcc tgcggcaaac aaatcgttgc
     2281 cggacccatc gttgccgggt tcgtcatgac ttcaaaggcc cgcaataacg cggacatcaa
     2341 ctgctctggt cgattgatgc ggtcccagta gcgagaaacc gcttgaaatg catcatttgt
     2401 cgaaaaggct acactgcttg catgttccag ctgctgcaag accggatcag gctgacgtgt
     2461 agcaaacgta tccgccggta aaaaaagtac ggggatatta tttgcgaatg ccgtacccgc
     2521 tgctgttaac agattggccg cgcccggtcc aacagatgtt gatacggcaa aaattttctt
     2581 gcgtaaattc tgtctggcaa aggcagtagc cgcatgggcc attccctgct cattttttcc
     2641 gctataactt ttcaaatgtc cgggctctaa ttccagcgcc tgaccgatcc ccaaaacatt
     2701 tccgtgacca tagacatgaa agataccttc aacataaggc gtttctttgc cgtcgatgct
     2761 gatgtattgt tgattcaaaa attttagtaa tgcttgtgct gttgttaaac aaaccgtctt
     2821 ttccattttt ttcaccttaa atccgagcga tcatttcgcc gtatatttct ttctccaatg
     2881 taataaaatc ttttacctcc tgagtcgtcg gtaaagaatc tgaacagtta ttgcttttga
     2941 ccatcattga tgcttccgct gagccaaact ctaaacaatc gatgatctcc cagccttcga
     3001 ataaaccgta taagaaaccc gagccgtaac catctccgcc gccaaagcct ttgcgtgctt
     3061 ccaccggaaa cggcttgatt gaaaactgct gctgatcggc cgtataagca gtcgatcctt
     3121 tcattccatg tttgattacg acaatctcag caccacaact gtgccaaaaa gcagcgcttt
     3181 cattatctga catgttaggc tggatcaact tctcagttag atcgaactct tctcttgaac
     3241 ccatgataat gtctgattcc ttagcaatca tcgaatagta aattgaaata tcatcgttgt
     3301 tcttccagtt ataagcacgg taatcaatat caaaaataat tttgacatta ttccttttcg
     3361 ccagcatcac tgccttgatt acggcttctc tggacgggct ctctgctagt gcagttcctg
     3421 agattaatag tgcttttgac cgtttcaagt agtcctcatc aatatcctca acgctaagct
     3481 gcaggtctgc ggcttgattt cgatacatca aaatattact ttcctttgat gagagcattt
     3541 cggtaaaagt cagccccagc ttttcaccat gctgcgcttt gctgatctga gacgtatcga
     3601 tgccttgttc attgaaataa tcgatcacat attcgccaaa ctgatcgtcc gagactgttc
     3661 cgataaaacc agctttcatg ccatgtttag taacacccac agcaatattg gcaggagatc
     3721 cgcccacaaa tttttcaaac atatggacct ttttcaatgg tttaaactct tctttgactt
     3781 gatcattgta ggcaggatta aaatcaatag cgactcttcc taaaagcagc aagtcaaatt
     3841 cttttgattg gtcaaacttt atataactca atatatccac ctctttatcc gttcttctat
     3901 ttctgaggca agtatagcac gccaaaacaa agcgtgcaat atttatttta gaacgcaata
     3961 ttgcgtgctg tttgaaaatg acggcaaaaa aaacgtgaat cgccttacat cacgattcac
     4021 gcctagatta aatattgtat tttgtcttaa taattatatc agtaaatagc gcatcttttg
     4081 taaccgtttt attattttgc agctgattcg ctaacatcag taatgaacga tagccttgaa
     4141 caaatccatc ttgatcgatt agaaaatcaa cctgatcgtt tttcagcatc tcgatattgt
     4201 tcttagtcaa atcataaatg attacaaagg gccgcttgct ttcatcgatt ttttccaacg
     4261 ctcgggcaat tcccgcttgt ccgccagaaa agacgactac gccatctaag tttgaataat
     4321 tctccaaggt gttgcttaaa atcttttcaa cctcagcact cgaatcaaag ctgctctgaa
     4381 cacccgtcag ctccagttca ggaaacgact ctttcaattc ttcaacaaag cctgccaccc
     4441 gtaagctgtt gacgctattt ccaaagtagc cggtaatcgc tagaaccttg ccctttcctt
     4501 ttgtcagcat acctaacaat cccgcagccg tttttccgct tttgaagttg tccatcccaa
     4561 caaaacactg tcgattcgta ccaagaatat ccgaattaaa ggtaatgatg aggatgcctt
     4621 gatcggtcaa ttgattaatt ttttctctga taccatcact atctactggc atgatcgcga
     4681 tcccttttac tccaagctcc accaatcgat ccaacgcctg cagctgggcc gcttcatcga
     4741 ccccgtctac ctcttctaaa aaacaatcaa tgtttcgctt ttttaaatcc ccgataatag
     4801 attccagacc tgatcggatc ggaatcataa aagaagattt cgccaattga gtgacaatcc
     4861 ccagcttgag cgttgtctct tttatgacct tctttttctt tggaacatag ttcatttcct
     4921 tggcgattgc tctgattctt tctgcaacct caggattgat ccttcctcga tcgttcaatg
     4981 cccgatccac tgtccccctt gacactcctg ctttctcagc tatttcttta attgtacccg
     5041 ccatcttgcc tctccttttt tcctattgtg tttattttat cacaaaa
//
LOCUS       DADGKS010000147         5040 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.152, whole genome shotgun sequence.
ACCESSION   DADGKS010000147 DADGKS010000000
VERSION     DADGKS010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5040
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.152"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(91..1176)
                     /gene="xerS"
                     /locus_tag="JXV47_002913"
     CDS             complement(91..1176)
                     /gene="xerS"
                     /locus_tag="JXV47_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HAX1488885.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
     gene            complement(3252..3770)
                     /locus_tag="JXV47_002914"
     CDS             complement(3252..3770)
                     /locus_tag="JXV47_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HAX1488886.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
     gene            4888..>5040
                     /locus_tag="JXV47_002915"
     CDS             4888..>5040
                     /locus_tag="JXV47_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAX1488887.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELTASAFDKW
                     VKQSKTS"
BASE COUNT         1672 a          823 c          775 g         1770 t
ORIGIN      
        1 tataaaaatg ataatgaagc ttgcctttaa agttgggctt ttatctaatt ttagagacag
       61 gcttcattat tatactattt tttactacat ttacaaagcg ttcaaagcat caattgtagc
      121 tgcattgtct atatgagtat ataaagttgt tgtatttgta cttgtatgtc ccaattgttg
      181 ggcagttaat accaatgaat ttgtctgttg atagagtcta gtagccaaag tatgacgtaa
      241 tttatgtgga ctgacttgga ctctgaatcc ttttgaatat tttgctacca tccgttcgat
      301 tgcaataccg gatatacgct tggcttctcc ttgataaatt gctagaaata aagctttttc
      361 gttttctgtt actttgtatc gttctttccg aatagctaga taattagcta aatattccat
      421 tgcaaatgct gctatattta ctgcgtctct cttatttcct tttctagtta ctaccacatt
      481 attcttttct aaagataggt cctctaaatt aatatttaca acctcggaga gtcttaatcc
      541 agatcctaaa atcaatgcat tgatcgccag gtctctttct acatctcgtt gataatagat
      601 caaagctcgt ttgctcaaag tttttttata ttcattggca atataatcta gataattttg
      661 tgtatcttcg tctagaaata attttttctc gattgcgttt gcacgggcag ctaacgtagt
      721 tttatctgtg atagttgcta cttgatccat aggattattt tctaagtatg gttttcctaa
      781 aggattattg gaacttttcg aaagatattt aaatagaacc tttaatgctg tgatatttct
      841 attgatagta gaagtagata gacctaagtt attattatct ttgagcttag tttttgttgt
      901 ctcttttttt acattttcct ttgtgcgacg tttcaaatga gatttgtaca agtttagatc
      961 ataggcagtt aactgtctta tcgaggtgat tgaagtatcg ggaacgatag actcactcag
     1021 aagccattca taaaagagct tataattttt tagatattct aaagtagttc gaggtgattg
     1081 atctttatcc tcacgatctt gaacaaaatc ttttatataa tcgggcatat gaagtatgat
     1141 tgtatctatt ttttgatata tttctgtatt tttcatgtta ttcatccttt cgataagtag
     1201 gggagaggag tatctctata attggactat accaattata gagtgttttg tcaattggta
     1261 tactctgaaa tttattaatt tatttcaaaa aagcagataa ataggtatag atttaataat
     1321 ttaaaataaa tggtatacat gaataggaaa ggaaacagaa ggaggcaatc ttaatttttt
     1381 aaattgtcta aattatatag aaagaacaat ctttctatat aattagacat aagagagact
     1441 acggttgatt tgatattaac aagcgtatat gaatgtatat acaaataaaa aaggggaggg
     1501 agaagttaaa gaaaattcag agaagtgggg cactcagtag tattaacaat ttaaaaggaa
     1561 tttcttaaag aaaatgggtt gcatcctgga gatacaattt ttttagataa agaaaaaatt
     1621 caagcaacaa ttcaaaaaaa tcttaactgc tgagattgat gtagcaatat ctcaatcatc
     1681 aacaaagtac gatcctgcct ttcaaaagct tattgataaa tgtttattca ttataaaaat
     1741 aaaagaaaaa tttatgtcag cttttttcat caaagtggta atgataattc gtctattaat
     1801 tgtatttttt aggaaatatg gtataattgt tttaacgaaa aggtaattca tgatacacca
     1861 aaaaccacta gctggcgggc tagtggtttt cttttacgtt ctattcagat taacgggtag
     1921 gcttactgtc ttttttggca ataattttgc aatcaagcca tttacagatg taatgcgcgg
     1981 atacttctgc taagattgca aaaaacatat cgaaaaggta attcataata caacctcctc
     2041 cccttgccat aataggccgg ggtagcagac agcataaata ttataccata actgaaaatt
     2101 tcattttagt acatttcaat atattgatga accagcacaa taaaacatgc catgactaac
     2161 agaaaaaaac ttattaaacc agatataact tgtaaacatc caactatata gaaaacgtaa
     2221 attttctata tagttggatt aagataacga ctatttattt tatcatattt ttactatacc
     2281 ctatactttt acttggtata tttatgaata atcgcaaatt tacccctata ctactagttt
     2341 gtaagttaga ttaataaaaa tactaaagtt atttgttctt ttattaaata cacctacaac
     2401 ttataaattg atggtattta gataacacga aagaataaaa ataacagctg atagtaaagt
     2461 ttgttgacga ttgctactca atcgaaagtg agttagtgcg tatgaacttg cttctgaaaa
     2521 cttatgaaat gaaagacctt ttacatcttg cagaaatcgt tactgggatt aaactaagca
     2581 ataaaaacta atgttcccct cattctttga acttctacta tttgatttat ttattctgat
     2641 aaatgacgat ttcaccttca ggatcttcaa atcccgtata gaatttattt aagatctctt
     2701 cagtatcagt aataggatag gcgataggcc acataccctt tgatggttag aataaactgc
     2761 tcaaaatctg tatcgtatgt tggctttagc atattaacaa aggctatctc caaattataa
     2821 accataagcg ttgaatcgtt cttaacaatt tcaattcttc ctaacccaaa gtcagaagat
     2881 ataattaccg gacttgcctt acccttcatg tgggttgttg agattccata tttaaaggga
     2941 attgtcggta ctatcggcgg tctgaaaaac atcccaaaaa taaaaaaatc tttcccctgc
     3001 tagtctccta agtccctttg tagcggatat ggcaccataa tctcatttta tcgaagtgag
     3061 tcatggttta tctgttggcc aaccaaaatt gatacaatct aacgatgcac cctctacggc
     3121 attctagggg agtgcacttg cattcaccca ataaaaaccg gcagttagca aagaacttat
     3181 gtagtcgtat gttcttactg ttaacataca agaggtctcc tttccacaat tgcttagcag
     3241 taaacgggaa tttacaaagc taatctcttc cattttctta tctttgttct aaaagtccca
     3301 aatggagcaa ctgtatttac atgaataaat ttatatactt cccatacagc cgttttggtt
     3361 gcctcgtctg cccattttct tttgtgtgca gtgaatagat cttcatcact cattgaatca
     3421 atcatcatgt taatatcatc aatattacga ttgagaattt cctctaattc tttcaatggt
     3481 agatgtgcat aggtatttgt aaaccactta tataactctc ctaactgatt ccatttaaat
     3541 tgatcagaag gcgttttaac agataatcca tttctttcat cattttccca ttttagaatt
     3601 aaattcgtcc aaccaacttg atatgctaaa ttttcagcag gtgttctatc cacttcctca
     3661 actcttttat ccttcaattc ttcaggaata gtttcaaatt ctaaaatata tttagtataa
     3721 gtcctattta tttctttttt taattcttct ttatttttat atgttctcat tatattacct
     3781 ccataaattc ctaattgtct cctttaattc atctataatt tcatccacga tattttaatc
     3841 cgttctacaa tgcatatctg atatgcattg actgtctaac tcatatgtga atgatttata
     3901 aaatatccca acgtctcatc taaagaaatg ttgatcgtca gcaaggagct aaaaaatacg
     3961 aatatatttc ttttgtagta aaatcggact ggtttgcata tcattttctt cgtaaatatc
     4021 aaaatcatgt taactactat caattactaa taaaaactac cactttaagc gttaagaact
     4081 gttaagttta gttaagtgag gatagttcac aaaatccatt gttaaacttc acgaaagtgg
     4141 taaaactcaa aatgctttat ataggattac agcatcgctc tttcttcgat tgcgcgttgg
     4201 gtaaaaaata ttatgaagta aaaattgacg atgacacgtt ccttacggct catcagatga
     4261 aacagctaca aaaacgaaat gatcaactcg aagaaaattt aattctaaaa aagcgattgc
     4321 catattcacg cctcgctcga cgaactatta aaggtcaaga tttacctgaa gatcatcctt
     4381 tttaggaaat tgaagctttt tatgttgcac aatgcattta taatactaca atgatgtttt
     4441 caccagatat tcttctaggg tgcggtgtaa tgaaacagat acacttgcaa aagaaaattc
     4501 accgcgaatt tactaaaatt atgaataatt atgttaatct tccgaaattt ttttccaaaa
     4561 ttaagggatc aagctggtgt tatagattgt ttaaggttgg caaaaaaata acttcttttt
     4621 aaacaattat agaaaaccga tactctgtta agttggttga cacggtgtcg atttttatga
     4681 ctttcttatt ctgaaacttc actaacggac agtacctaaa aagtctatag tatggacgtt
     4741 tacgagtact attttatcaa aaatgctgct catttcaact tatatgtttt agtgaactac
     4801 ccccacttag cttggatagg ctacaattaa ctagacagaa aaattaaggt gtgtagacta
     4861 gaagaaaaca taccaggagg aatttttatg tctaagagaa cacgaagaac tttttcacaa
     4921 gaattcaagc aacaaatcgt caatctttac ttagctggaa agccacgtgt agaaatcatt
     4981 cgagaatatg aactaacggc ttcagcattt gacaaatggg taaagcaatc taaaacgagt
//
LOCUS       DADGKS010000148         4956 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.153, whole genome shotgun sequence.
ACCESSION   DADGKS010000148 DADGKS010000000
VERSION     DADGKS010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4956
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.153"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(55..828)
                     /locus_tag="JXV47_002916"
     CDS             complement(55..828)
                     /locus_tag="JXV47_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAX1488888.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMDNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            972..1322
                     /locus_tag="JXV47_002917"
     CDS             972..1322
                     /locus_tag="JXV47_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HAX1488889.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            1303..2019
                     /locus_tag="JXV47_002918"
     CDS             1303..2019
                     /locus_tag="JXV47_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1488890.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAAVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            2019..3467
                     /locus_tag="JXV47_002919"
     CDS             2019..3467
                     /locus_tag="JXV47_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAX1488891.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(3537..4046)
                     /locus_tag="JXV47_002920"
     CDS             complement(3537..4046)
                     /locus_tag="JXV47_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488892.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(4036..4761)
                     /locus_tag="JXV47_002921"
     CDS             complement(4036..4761)
                     /locus_tag="JXV47_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488893.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHSQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWRLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
BASE COUNT         1703 a          843 c          998 g         1412 t
ORIGIN      
        1 ttaagaaaaa ataagcgatt ttcttaagaa aagaggtagc ttcaaaaaaa gatcttaaat
       61 cagatcaaaa tacttcaatg cgtggacaat tccgccttct gtatttttct ttgtgataaa
      121 ggtagaaagt tcttttaatc cgtcataggc gttgtccata gcgattttgt tgtcgcaagc
      181 ttccaacaag gcaaaatcat tcggaccatc gccaaatcca aaagtaggaa ctttttccag
      241 ctgaagttct ttttgcagac gtttgacacc tgcccctttt gagattcctt tcttcactgt
      301 atcgatcgag taaggaccat tccgataaaa agttagctca ggaaaatgtt cgtgatagta
      361 ttcgtcacct gattgagata agatcagcaa catatttact gtgttttctt taaagcctaa
      421 aggatcaatt tccggaacat ctgaatgaat gaagtcgtaa gcattgatca ttgtttggct
      481 atgaccggta caccagattt tctgatcgtt atagtaagaa agttcatgac cgttcaactg
      541 tacatgatca tacatttttt gacattcttc tgaagaaaat gtttgagaat agatttcttc
      601 gccgtctact cgaatgaaag aaccattcat ggtgaccgca gaagtaatgc ccgcatcttc
      661 catgatagag tggatttctg cttctgtacg tcctgtagcg atgacgggga gaacattgtt
      721 ttcttttaat gcgttcatag cttttgccac ttcgggtgtg atttttgatt tcgcatctag
      781 taatgttcca tcaagatcaa agaaagtgat tgcacgataa tttgacacaa ataaaactcc
      841 ttttttattg gaataagttt atcttaacaa agaatgaaca aaagacaaac ctttcgtgaa
      901 gaattcctga acatattggt tcagtcaaca atttagagta tactataaga agagaattta
      961 ggagggaaag aatgattttt ttcagtattg gtatcttatt cttaataatt ggcagtcttt
     1021 ttcggattct gccctcaaaa ggaaatctgc ctttttatgg gtatcattcg cctcttgccg
     1081 caaaaacaga cgctcattgg cggctggctc aaaagacaag cggaaactgg ttttttctta
     1141 tgggcttact gatggcattg atcggctatt atttaaagac atctgggcat acgaattatt
     1201 ttctgattga aatgcttctg ctagtatttc caattatgcc tatttttatt atgacagaaa
     1261 agaaattaca gaaatatgac ctggaaactg gagggaacga taatgaatat tttaatgatt
     1321 gaagataatc aatctgtttc tgaaatgatg cagatgtttt tcttaaatga aggttgggaa
     1381 gcaactttca agtatgatgg aaaagaaggg ctcgatgcct ttttagaaaa cccacaacat
     1441 tgggatatga ttacactaga cctgaatttg cccacactgg acggtatgct agtaggaaga
     1501 gagatccgca aagtttcaag tactgtgccg attatcatgc tgacagctag agattctgaa
     1561 agcgatcagg tgatcggctt agagatgggg gcagatgatt atgtcacaaa acctttcagt
     1621 cctctgacgc ttattgctcg aatgaaagct ttgcatcgcc gtagtgagtt ggcagaagca
     1681 agagaagaag cagcagtttc agatgatcat tttgatatcg agactagtca tttcaagatg
     1741 aatacgaaaa cacgagaagc gtatctggac aaccggccaa ttgaaggact gacgcctaaa
     1801 gagttcgatc tattgtttac tttagcaaaa aaaccacgtc aagtattctc tcgggagcag
     1861 ttgcttgaat tagtctggga ttatcagtac tttggtgatg aacggacagt ggacgcccat
     1921 atcaagaaat tacgacaaaa aatcgaaaag gtcggaccac aagtcatcca aactgtttgg
     1981 ggagtcggct acaaattcga tgattctggt gttgcctaat gcgttatttg tatcagcaac
     2041 tcttagcttt ttgcggaatg gtcgcgttga tcttattgat cgttggagtt tcttttacac
     2101 aactgacaaa acaaacgatt gaagaaaaca attaccagca actgtttgga tatgctgaat
     2161 cagttgaaaa gacaacgcaa acctatgccg atacgctccc gcagtttagt caagatcagg
     2221 cgtttcaaaa tgcattgctg ctgacagagc aagtactgac agaacaaaat gtgaacttta
     2281 tatttatcga taaaaacgaa cgtgtcattt atccgactaa tacagcttta ctgaatttta
     2341 ccttaacagc tgatcaatgg aaaaatctga ggaatggacg tcaagaaaaa ttcacatcga
     2401 ataaaaatat tttaggacaa gcacaggcga cctcttacgc acttgtgcca tttaatttga
     2461 atcatgaatt ctatggagca cttgtagtta gtcaacctgc gcgaaatatc gataacagcg
     2521 ttcgtccaat tacactgaac ctgttcaaag gatttatttt ttccagtatc gttgcagtta
     2581 ttgccagcta tgcttttgca gcattccaag ttaagcgtat caatcggtta aggaatgcga
     2641 cgaaagaagt gacgaatggt aattttgatg tacagctccc cgtacatgac aaagatgaat
     2701 ttgatgagtt agcagatgat ttcaataaaa tgacgaattc attgaaagaa tctcaagcag
     2761 aaattgaaga acaagaaaat cgtcgaagac aatttatggc agatgcttct cacgagatga
     2821 gaacacctct tacgacaatc aacggacttc tggaagggtt agaatacaat gcaatccctg
     2881 aaaatcagcg agaaaacgcg attaaattga tgaaaaatga aacagagcgt ctgatccgtt
     2941 tggtgaatga aaacttggat tatgaaaaaa tccgtacgaa tcaaatcagt atggtcatta
     3001 aaaaattcaa tggaacagaa acattgaaaa atattgttgc acagttagaa gctaaagcag
     3061 aagcagcagg agatacattg acattgaaag ccgttgatga tattgatgtt tacgctgatt
     3121 atgaccgatt tgtccaaatc atggtcaata ttattcaaaa cgcgatacag tttactgaaa
     3181 acggccaaat cacgattact ttagaaaaag gctatcttga aacgatcatc acgattgaag
     3241 atacgggaat tggaatgtct gaacaacaaa tgaaaagtat ctgggatcgt tattataaag
     3301 tagatccttc aagaaaaaat acaaaatatg gtgaatcagg attaggttta ccaatcgtgc
     3361 agcaacttgt acgcttgcat aaaggaaaat tagaagtaga aagcgaacta ggaaaaggaa
     3421 caaaattcgc tgttcgtttg cctgacgtag aaatcaaaaa agagtaaaaa acaagcggta
     3481 taaaagatca tgaatcgatc ttctataccg cttgttttta ctataaaatg attgatttag
     3541 cccgcgggct ctaaacgatc aatataagga ctttgagcaa tagtagcatc atgagtaaag
     3601 agtaagatac cttgattttc ttcatgagct aaataagaaa gcaagtggag tagctcttgg
     3661 atctccaata cactaagttc atcaaatgta tcttcaataa caatattgtt tcgcttggaa
     3721 agcaaggcat gaagtaattg cagctttact ttttcaaaag acgtcaactc agctgccgca
     3781 caattaagca aggaaggaga gatatcaagt ttttcttgat aggccaaacg atcttgtttg
     3841 atttcttttt ccggtacatc caacaggaca tggtctttaa gattcagata aggaaacatc
     3901 ggccaatttt tttggatgat cgcaaaatta tccagttttg caacaagaac ctcttttttc
     3961 aagtgctcca atattttatg ctgtttttcg agaggacaca aaataacggt caagtgttca
     4021 gcatgaatca aatattcagg tttcattacg tccaggcctc ctactttgca aatgatggat
     4081 aaaaaaagtg aaagggaata gactaagaat gagacagcat ccactgagcc caataagagt
     4141 ttgggcaaat cccttaagta tatctgtgaa aaaaagatca ttttggaaat cgatggtaaa
     4201 aaaagtctgt tgatccatcg gaattgtaag tccgcttacc gaagtcaaga tatcacggat
     4261 atctggcagt tcagtagtct ttaagacaag aaaattgatc ctttgaagaa gcgcttcata
     4321 aactgactgg aagctgacga tccacaataa aaccaagata caacaaagaa agagaggaaa
     4381 gaacagctgc cagaaaataa aaaggaataa tttggtttta gaaagaccag tcaggcgcca
     4441 attgatcaat tcctgcttgt tttgcctgac tgaatagtaa aagaaaaaga taaaaaggaa
     4501 ggcaaataga aaaaataaac tgaatatgcc ttttatataa aatcggctag ctaattctaa
     4561 agccggaaga agctctgtag atgcagaagc gccaataaat gaaagccgat cttggacttg
     4621 attggctaaa gccgattgcg aatggtaaag agtcaggcat gctatcaata aaaaagcaga
     4681 aaagcttgaa aataaacaat agagtattgt ctgctttttg taataaatta atcgagcagt
     4741 agcatagcgg attattttca tacttttcac ctctataaaa agtatagaaa atgaatatga
     4801 ataaagtatg aaattccttt agtgaaatca cgaattaaaa ccagaaaata ttttgtaaaa
     4861 agcaagaggt tgtgaagaag ctgccctatt ctattaccgt agatgcaagc ttttgaacac
     4921 tgtttattcg aaaagaggag cagcgacaat aatttt
//
LOCUS       DADGKS010000149         4926 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.154, whole genome shotgun sequence.
ACCESSION   DADGKS010000149 DADGKS010000000
VERSION     DADGKS010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4926
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.154"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            85..972
                     /locus_tag="JXV47_002922"
     CDS             85..972
                     /locus_tag="JXV47_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAX1488894.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="JXV47_002923"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="JXV47_002923"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HAX1488895.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="JXV47_002924"
     CDS             2274..2720
                     /locus_tag="JXV47_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAX1488896.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="JXV47_002925"
     CDS             2993..4345
                     /locus_tag="JXV47_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase"
                     /protein_id="HAX1488897.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4516..4803
                     /locus_tag="JXV47_002926"
     CDS             4516..4803
                     /locus_tag="JXV47_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488898.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1695 a          813 c         1030 g         1388 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4441 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4501 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4561 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4621 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4681 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4741 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4801 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4861 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4921 aacccc
//
LOCUS       DADGKS010000150         4747 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.156, whole genome shotgun sequence.
ACCESSION   DADGKS010000150 DADGKS010000000
VERSION     DADGKS010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4747
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.156"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            133..636
                     /locus_tag="JXV47_002927"
     CDS             133..636
                     /locus_tag="JXV47_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAX1488899.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKEQIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCNLAEELEGTPIGEAASEIQHAFFNSFEEMVEH
                     VDDIVYYPDCDDMSDVAHYLIVEAGDFGEVPEQLKPYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPE"
     gene            763..1800
                     /locus_tag="JXV47_002928"
     CDS             763..1800
                     /locus_tag="JXV47_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488900.1"
                     /translation="MANIQTSFIDFHNSIRLDVEDNTLLKDYKDQVIDGLKDYLPDDV
                     KFETFLQGSYSVYTGIKSCDEKIDFDIDIAVAFEIDHTVYEDPREPKLWVKEALVEIF
                     PNAQVNLKVPCVTATFTGKKTKKNVHVDVAVYAKEDENYFLAKAKEFSAPENRCWEEA
                     DPKVLKEKINSHVADSDDRKQFRRCIRYLKRWKDNNFNQEYKPTGIGLTINVMDTFLV
                     NKSTDFLTRKVQYNDMECMKQIVSSLKDSFVYEYSETDGWHYRLHAYLPVKPNSDTYS
                     KMTVNQMSDFKNKLSKLYDDLIFAIDTEDEYEATKRLNNQFGEDFLIISEEEVTEKNL
                     RNAFVTDYPSA"
     gene            1815..3512
                     /locus_tag="JXV47_002929"
     CDS             1815..3512
                     /locus_tag="JXV47_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HAX1488901.1"
                     /translation="MDYTDILKEKLTDVVRLFDGNYYGDFSFATIGKLRLKIEIPKHF
                     PLVLPRIYIHNFDHLGLYLPHVEKDGLVCFSSDINYLVDEENSELVLLQCVNKTIKTI
                     EEGLKGLNKNDFRKEFVAFWDKQENQISLFYLCEPALFIKSVDTIMYGKSLVALDKEN
                     ELQLNAASRLFNGEKEDTHELDAYYVPIRNKNNIMPPKNNKAWSKKDILQIVKKNVTG
                     ANKRFFLKLEKRKNRHNVLLILDIPIEEKSNNVIIGFLFTKQSGSIKDYKGTPRTVLV
                     QRHDELYLVNRTSGENYGLGANIAIVGVGSVGSKIAENLGPLGVRKMTLIDNDCFQAE
                     NLYRNSLGADSLKNARSQNNFFKVDLMQEELEKKIPYLCVEVESMNVLDLISMQPGFF
                     KEYDYVFVCIGDTMASLALNNYFSKSSQKVFYSWLEPYGIGGHTLFINYSLNQKGCFN
                     CLYTDSNSKNRCSNRASLVKEGQIFERTLASCRSKFIPYNAIASTECAINAIKLFHKV
                     NQNNMTNSTLFSWIGDGSTFENLGYQYSDRNTFLNGVNKFEERFFSKYCKVCGELDD"
     gene            3505..3966
                     /locus_tag="JXV47_002930"
     CDS             3505..3966
                     /locus_tag="JXV47_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488902.1"
                     /translation="MIKFSCDRIVIEVRDEVLKIFEQYRQGKDDLPEAGGVLHGKRLK
                     NGSIIITDITTPQIGDIQKRLLFKKNREIHQQLSNEKWIESNKFSIALGEWHTHPEAV
                     PTPSNVDKKSWRLNVSKQHDDRVYVFIIVGFSDLRMWLLSKKSDIRQAIKL"
     gene            3979..>4747
                     /locus_tag="JXV47_002931"
     CDS             3979..>4747
                     /locus_tag="JXV47_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488903.1"
                     /translation="MKSQKNIWWWGFLVGKVMIPALLLISLPMITFFFTNKKMSKEAV
                     IFFFGDQKATFIETLVTSLQLNLNYIFSIIIVISLLNFFKKRNSGKVFNSNGNVYYNY
                     FYFVFWVAATLLGYDKIQIAGIPIHMQYKLVLSGIFSEVLPDIYDDHYDSDGTCKVSI
                     EKENFDDIDGYDSVNLLIIDTYDIKMSELSMENQTYPTIIVRGNSIDGVRKVNRSLIL
                     EIKKTMDEIQKSDFKKVFVASTSNPKNSINIINSSFRF"
BASE COUNT         1669 a          589 c          956 g         1533 t
ORIGIN      
        1 gagttttcca aactgattgg cttcttggtg attgctttga ttgcggtagg tctggtcttt
       61 aatgcttctg gtgtgaagga tgtcctactc aatttgttta accgaattgt cggtgcctga
      121 gggggaatca caatggaaca gatgcgtgtt tatattgcga accttggaaa atacaatgaa
      181 ggtgagttgg tgggggcatg gtttacccca cctgtcgatt ttgatgaagt gaaagaacag
      241 attggattaa atgacgaata tgaagagtac gcgattcatg attatgaact gccttttgag
      301 attgatgagt atacgccaat tgaagagatt aatcggttgt gtaacttagc ggaggaacta
      361 gaaggaacgc caattggtga agctgcttct gagattcaac acgctttctt caattctttc
      421 gaggaaatgg tagagcatgt ggatgatatt gtctattatc cagattgcga tgatatgagt
      481 gatgtggcgc attacttgat tgtagaagct ggtgattttg gcgaagttcc agaacaattg
      541 aagccgtata ttgattttga tgcttgcggt cgagatttgg agattggagg aaattatttg
      601 gttactagtc gtggagtttt tgagtatcca gaatgaatca aacactatat atagtgtttg
      661 attagtatat gtaagcaaaa aaacacaata tatagagtgc aaactgaagg gtaatgtgat
      721 ataatatttg ccgaagaaat atttttgaaa tgaggtaata ttatggcaaa tattcaaaca
      781 agttttattg atttccataa ttcaattaga ttggacgtag aagacaatac gctacttaag
      841 gactataaag accaagtaat tgatggatta aaagattact tacctgatga tgtgaagttt
      901 gaaacttttt tacagggaag ctattctgtt tataccggaa taaaaagctg tgatgaaaaa
      961 attgattttg acatcgatat tgcagttgct ttcgaaattg atcatactgt ttatgaagat
     1021 ccaagggagc ctaaactgtg ggtaaaagag gcgctagttg aaatttttcc taatgctcaa
     1081 gttaatttaa aagtaccttg tgtaactgct acatttactg gaaaaaagac aaaaaaaaat
     1141 gtgcacgttg atgttgcggt ttatgctaaa gaagatgaaa attatttctt agcaaaagca
     1201 aaagaattca gtgctcccga aaaccgatgc tgggaggaag cggatcccaa agtattaaaa
     1261 gagaaaatta atagtcatgt agcagattca gatgatcgaa aacaatttcg aagatgtatt
     1321 cgctatttaa aaagatggaa agataacaat tttaaccaag aatataaacc aacaggaatt
     1381 ggacttacaa ttaatgtgat ggatacgttc ctagttaata agtccactga ttttttaact
     1441 agaaaagttc agtataatga tatggaatgt atgaagcaga ttgtttcttc gctgaaagat
     1501 tcatttgtgt atgagtacag tgaaacagat ggttggcatt atcgtctaca tgcatatctt
     1561 ccagtgaagc ctaacagtga cacctattca aaaatgacag tgaatcagat gagtgatttt
     1621 aaaaacaaac tttctaaatt atatgatgat ttgattttcg ctatcgatac tgaagatgag
     1681 tatgaagcta caaaacgatt aaataatcaa tttggggagg attttttaat tatttcagaa
     1741 gaagaagtta cagaaaaaaa cttaagaaat gcatttgtta cagactatcc gagtgcttag
     1801 gttggtgtta aagattggat tatactgata ttttaaaaga aaagctaaca gatgttgtgc
     1861 gtttattcga tggtaattac tatggggatt tttcatttgc tacaattgga aagttgcgtt
     1921 taaaaattga aataccaaaa cattttccat tggtacttcc taggatttac attcataatt
     1981 ttgatcattt aggactttac ctaccacatg tagaaaaaga tgggttggta tgtttttctt
     2041 cagatataaa ttatttagta gatgaagaaa attcagaatt ggttttattg cagtgtgtta
     2101 ataaaactat aaaaacaatt gaggaaggtt tgaaagggtt aaataaaaat gattttcgaa
     2161 aagagtttgt tgctttttgg gacaaacaag agaatcaaat ttcgttattc tacctttgtg
     2221 aaccagcgtt gtttatcaag tcagttgata caataatgta cggtaagtct ttggttgctt
     2281 tggataaaga gaacgaatta caattaaatg cagcgagtag attgtttaat ggagagaaag
     2341 aagatactca tgaattagat gcatactatg ttccaattag aaacaagaat aatattatgc
     2401 ccccgaagaa taataaagca tggtcaaaga aggatatttt acaaatagta aaaaaaaatg
     2461 taacaggtgc aaataaaaga ttttttttaa aacttgaaaa aagaaagaat agacataatg
     2521 ttttacttat tctagatatc ccaattgaag aaaagtcaaa taatgtcata attggatttc
     2581 tttttacaaa acaatctgga tctataaaag attataaggg tacgcctagg actgtattag
     2641 ttcagcgtca tgatgaatta tatttggtga atagaacgag cggagaaaac tatggattgg
     2701 gtgctaatat agctattgtt ggggtagggt cagttggcag taaaattgct gaaaatcttg
     2761 gtccattagg tgtgagaaag atgacactca tagacaatga ttgttttcaa gctgaaaatt
     2821 tgtatcgaaa ttcacttggt gcagatagtt taaaaaatgc ccgatctcag aataattttt
     2881 ttaaagttga tttaatgcag gaggagctcg aaaaaaaaat cccatacctt tgtgttgaag
     2941 tggagtcaat gaacgtttta gacttaatta gtatgcaacc tggttttttc aaggaatatg
     3001 actatgtttt tgtttgcata ggagatacaa tggcaagcct ggctttaaat aattattttt
     3061 ccaaaagtag tcaaaaagtt ttctattctt ggctggagcc atatggcatt gggggacaca
     3121 ctctatttat aaattattct ctaaatcaaa aaggttgttt caattgtctt tatacagatt
     3181 caaactctaa aaataggtgt tcaaatagag cttctctggt aaaagaagga caaatttttg
     3241 aaaggacttt agcgagttgc cgctcaaaat ttataccata taatgctatt gcctcgacgg
     3301 aatgtgcaat taatgcaata aaacttttcc ataaagtcaa tcaaaataat atgaccaata
     3361 gtactctttt ttcatggata ggagatggga gtacttttga gaatttagga tatcaatata
     3421 gcgacagaaa tacttttctt aatggagtca ataagtttga agaaagattc ttttctaaat
     3481 attgcaaagt atgtggggag ttagatgatt aaattttcgt gtgaccgtat tgtcattgaa
     3541 gtaagggatg aagttcttaa gatatttgaa caatatcggc agggaaagga tgacttgcct
     3601 gaagctggag gagttcttca tggaaaaaga cttaagaatg ggagcataat aattaccgat
     3661 ataacaacac ctcaaatagg agatatacaa aaaagattac tctttaaaaa aaaccgagaa
     3721 attcatcaac agctttctaa tgagaaatgg atagaatcaa ataagttttc tattgcattg
     3781 ggagaatggc atactcatcc tgaagctgta ccaactccat caaatgttga taagaaaagc
     3841 tggagactga acgtgagcaa gcaacatgat gatagagttt atgtttttat tatcgttgga
     3901 ttttctgatt tgagaatgtg gttactgtca aaaaaatcag atattaggca ggctataaaa
     3961 ctataaagga gtgattaggt gaaatcacaa aagaatattt ggtggtgggg gtttttagta
     4021 ggaaaggtaa tgataccagc ccttctctta atttctctac cgatgattac ttttttcttt
     4081 accaataaaa aaatgagtaa agaagccgtg atttttttct ttggagacca aaaagctacc
     4141 tttattgaaa cgttagtaac atctcttcag cttaatttga attacatttt ttcaattatt
     4201 attgttatat cgttattgaa tttttttaaa aaaagaaatt caggaaaggt gtttaactct
     4261 aatggaaatg tgtactacaa ctatttttat tttgtatttt gggtagcagc aactttactt
     4321 ggttatgata aaattcagat tgcaggaatt cctatacaca tgcaatataa gttggttttg
     4381 agtggaattt tttctgaggt gttgccagat atatacgatg atcattacga cagtgatgga
     4441 acatgtaaag taagcattga aaaagaaaat ttcgatgaca tcgatggata tgactctgtg
     4501 aacttactga ttattgatac ttacgatata aaaatgagtg aattatctat ggaaaatcaa
     4561 acatatccta cgataattgt tagagggaat tcaatagatg gagttcgtaa agttaataga
     4621 tctttaatct tggaaataaa aaaaacaatg gatgaaattc aaaaaagtga ctttaaaaaa
     4681 gtatttgttg cttcaacatc taatccaaaa aatagtatca atattattaa ttcatcgttt
     4741 agatttt
//
LOCUS       DADGKS010000151         4741 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.157, whole genome shotgun sequence.
ACCESSION   DADGKS010000151 DADGKS010000000
VERSION     DADGKS010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4741
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.157"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(25..1023)
                     /locus_tag="JXV47_002932"
     CDS             complement(25..1023)
                     /locus_tag="JXV47_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HAX1488904.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKATIETDTTIETKKSKTQS
                     TEQTTTEMKQSVETSASSITESSSEEVKNTLWDTNKASKLETFVTQWGKTLGQEYKSY
                     NLQNNVSLYGTPLPQAVINGDWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVETGE
                     YLGQHVYFFGFQNGQPKVYLTQQNQGNENNYLYFNETQNQQLKQGFSDIVNGQTPQTP
                     VVEESTQQATTTTTQSTSSSGISSWEAAKESVLNNKALWLYDSPDKNVSNTNLISTNE
                     YMKDLMQDENGSYYSINIVTDDDGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK"
     gene            complement(1098..1394)
                     /locus_tag="JXV47_002933"
     CDS             complement(1098..1394)
                     /locus_tag="JXV47_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488905.1"
                     /translation="MAKLIVLGGLIYGGYWLYQYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHTGYRHYWERID"
     gene            complement(1387..1680)
                     /locus_tag="JXV47_002934"
     CDS             complement(1387..1680)
                     /locus_tag="JXV47_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488906.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            complement(1826..2377)
                     /locus_tag="JXV47_002935"
     CDS             complement(1826..2377)
                     /locus_tag="JXV47_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HAX1488907.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFLRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            complement(2551..2850)
                     /locus_tag="JXV47_002936"
     CDS             complement(2551..2850)
                     /locus_tag="JXV47_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HAX1488908.1"
                     /translation="MLETAIEVLEKCAQLVTASEEWGYESVTMEKEEIEMGMLPEDVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTDE"
     gene            complement(2877..3143)
                     /locus_tag="JXV47_002937"
     CDS             complement(2877..3143)
                     /locus_tag="JXV47_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAX1488909.1"
                     /translation="MDSLPVELQALCWNLIDQNVQKQFPLDYLQIFEFSTEKGNQKLV
                     HRQEEPEERKEYLISPKLRLKSVSQKIWAIDSGEYQTMLLPEEY"
     gene            3430..4173
                     /locus_tag="JXV47_002938"
     CDS             3430..4173
                     /locus_tag="JXV47_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488910.1"
                     /translation="MVVSKLPRNEDYLTNYDGYVVTTEHFDLANPVTKVDDIPDYEMY
                     SQTIDSLNKRFGNRVLKGIKIGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDD
                     EVKDMDPAIVIPQYFAQLSEALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPIL
                     DQVIKNKLAFELNAKSAYLYDNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFD
                     DLFALLKANGVTELAIYQKGKRIMVPLPV"
     gene            complement(4210..4707)
                     /locus_tag="JXV47_002939"
     CDS             complement(4210..4707)
                     /locus_tag="JXV47_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1488911.1"
                     /translation="MNNQITLAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
BASE COUNT         1404 a          907 c          694 g         1736 t
ORIGIN      
        1 ttctttgata aataatattt tcaattattt aatcatttga aaattgttag tcattccaat
       61 acgttgagaa attcttccat ctgtataaac acgaaattgt tttccaccag ccatggtcgt
      121 gtttccatca tcatccgtta caatattaat tgaatagtag cttccatttt catcttgcat
      181 tagatctttc atatattcat ttgtgctaat taaattagta tttgatacat ttttatcagg
      241 agaatcatac aaccataaag ctttattatt tagcacagat tctttagcag cttcccaact
      301 tgaaattcct gaactacttg tagattgtgt cgttgtagtt gttgcttgtt gagtagattc
      361 ttctactact ggtgtttgag gagtttgtcc attcacaata tcactgaaac cttgttttaa
      421 ctgttgattt tgagtttcgt taaagtacag ataattattt tcattacctt gattttgttg
      481 cgttaaataa actttaggtt gtccattttg aaaaccgaaa aagtaaacat gctgccctaa
      541 atattctcca gtttctacat cagaataaac tgctactaaa ttgaaatctg catgaccagt
      601 tccatcttct gaccattgta cggtaactgg tgcttcattg attgccattt tccaatcgcc
      661 attaatcacg gcttgtggta aaggagtgcc atacagactt acattattct gaagattgta
      721 gcttttatat tcttgaccta atgtctttcc ccattgtgtg acaaaagttt ctaatttgga
      781 agctttattc gtatcccaca aagtattctt aacctcttca gaagaagatt cagtgattga
      841 acttgcactt gtttccacag attgcttcat ttctgttgta gtttgttcag ttgattgcgt
      901 tttacttttt ttagtctcaa ttgttgtatc agtttctata gtcgctttag tcctcgtatt
      961 ctcagatgta caaccagtga ataaaattcc cattcctatt agtaataaca gccatttttt
     1021 cattatattt ccccctttca atttctccct cacgtactta ttctatcaga caattaattg
     1081 atctaaatgg taatctttta atcgattctt tcccaataat gtcgatagcc cgtatggcag
     1141 cggtctcttc cttgaggact ctcagatgga ttaaaactag tagaaatttc ccttccacat
     1201 cctctacagc gataagttct cattattttt gggctattag tattattttt cttagttaga
     1261 gctatgagtc caactatgat taccccaact gtcttaatta cttttccttt atctatattc
     1321 ggatgcgcaa gcatatattg atataaccaa tatccaccgt aaattaaacc acctaataca
     1381 atcagcttag ccatgtactc gtctcctttc tttttgttta attacttttt gaatccatct
     1441 tgcagagaaa ccataaactt ctgtcaattg acggatatct acagtttttt cctgttctat
     1501 catgttttcg attctttttc taactaactc acgatcgtac attttcattg gaaaagaaat
     1561 ctgttgccct cgaaaagcaa gataaaattg atagagcaat tctgaatcca gttccatttc
     1621 ctcaaaaaag tcattcatac ttttataaga gttactcaaa caagtttcat caatctccat
     1681 ctacacaccc cctgttattt tttacataat gaaaatagca tattactggg tacattgata
     1741 attcatataa catgtatcat cacatgtatt tttaaagtca aaaagcatgt aaaactactt
     1801 ataagtaaca tgagaaaata aaatgttatt tttcttgaaa taataattga ctatctgcca
     1861 attgccattc attacgaaca tgaatactta gtgggtggga taacttacct tctgcattta
     1921 tcaatacttt ggtcatcttc ttttgtttcg cactcaattg atcgtaaata gtctttgctt
     1981 gttcataagc cacttgactc gtcgctgtaa tcgaaccaca agcaaaaata atggtattga
     2041 ttttcttttc tgtaaaaaca gtcgttaata tttccaaaga ttgttcatca tttcctcgaa
     2101 gaaatacccg aggacttttc gcttttgtgt acgaaaaaag attcacagca ataaaaccag
     2161 taaatcctaa ttgtcggata ttcttttcga ttaataacat actcaaatca ttcgtaaatg
     2221 gttctgtatc tgttggacga atagtaatga ctactgctaa tttatcttcc gcttcttttc
     2281 ctttgatcgc ccattgtcgt ttgaaaacat agcgatgggt atgatgagga tctcgccaaa
     2341 cttctgtttg tgtggtcact aattcttttt caatcatctc tttttctcct atgctatttt
     2401 ttgttcaagc acttcaatta ccattgccgt tataagtgtc aatactagtt gaaaatattt
     2461 catattcttt ctcctttttt cttcagaatt tgatgaatcg cggtaaggat atcttctaaa
     2521 catttcgcaa tcattctcaa ataatcgatc ttattcatcc gttcctccaa tctgactcca
     2581 aaccaatcgt ccttctacca gtaacccacg aacaaattct cgctggctgg taatatctgt
     2641 aatgaaataa actacatagt cttttccatc ttctggtgcg caataaatat aaagatgtgt
     2701 catcactaaa cgtggtagat gaacatcttc aggaagcata cccatttcaa tttcctcttt
     2761 ttccatcgta acggattcat agccccactc ttcagaagca gtgaccagct gtgcacactt
     2821 ttccagtact tcgatagccg tttctaacaa gtcctttcgt tcctttcttt tagatactag
     2881 tattcttctg gtaataacat cgtttgatac tcacccgaat caatggccca tattttttga
     2941 gacactgatt tcaaacgaag cttaggtgaa atcagatact cttttctttc ttccggttct
     3001 tcttgacgat gaaccaactt ttgatttcct ttttccgtag aaaattcaaa aatttgaaga
     3061 tagtctaaag gaaattgctt ttgaacgttt tgatcgatta gattccaaca taaagcttgt
     3121 aattccaccg gcaaactgtc cattactccc tttgtgacat aacgttatcc tttattttga
     3181 aacatttctt ttccctcctt tgccataaaa atagcccaat cttctattaa agaagattgg
     3241 gcttcatgga tataatatat atttgtaaat aaagttaatt cagttataat tatcaaaact
     3301 acacaattat taaagttttt catatctctt tgtttagtaa gtttttctaa atcttaaccc
     3361 gtggtgctag ttaatttttt cctagaggaa aatgtctaaa catgttggta aatcaacaaa
     3421 aaaacgcata tagtagtctc aaaactccca agaaatgagg actatttaac aaactacgat
     3481 ggttacgtcg tgacaactga acattttgac ttagccaatc ctgttactaa agtcgatgat
     3541 atccccgatt atgaaatgta cagtcaaaca atcgatagct taaataagcg ttttggcaat
     3601 cgtgttttaa aaggcatcaa aatcggttac atcgcttctg aaaaggatcg gatcatcgac
     3661 tatttagccg ataaagatta cgatttaaaa ttactcagtg tgcatcataa tgggcaattt
     3721 gattatttag atgacgaagt caaagatatg gatcctgcta ttgtgattcc tcagtatttt
     3781 gcacaacttt cagaagcact agttgttata gaagcagatg tctttgctca ttttgactat
     3841 ggttttcggg tatttggtct atccgttgct gaatttaaac aatatgaagc gcagttttta
     3901 ccgattctag atcaagtaat caaaaataaa ttggcattcg aattaaatgc taagagcgct
     3961 tacttgtatg acaatttagc gttatatgaa tatgtcatcg atttatatct ttcacgtggt
     4021 ggtaccttgt ttagtgttgg atcagatggg cattaccttg aacatttccg tttccatttc
     4081 gatgatcttt ttgctctgtt aaaagcaaat ggtgtgacgg aattagcgat ttatcaaaaa
     4141 ggaaagcgaa ttatggttcc attaccagtc taaaaaaacg tcctcagcat caaaagtgag
     4201 gacgtttttt tagatttctt tttctaaaat cggacaaata cgatcttgtt ttcctaaagg
     4261 aaaatgtttg atcccgattt ttttaaatcc atgacgttca taaaaacgaa tacctgcatg
     4321 atttttttca taaacagtca aacgtaaata acgtttttgt ttcgttttag cataacgatt
     4381 cgcttcatcg agtaaccgtt gccctaaccc tttgttttga taatctttga gcagatagag
     4441 ccgttgaatc tctatagcat ctttttcatc attgactttc atataaccaa tgagtatttg
     4501 atgatcctta ataccaataa atttactggt tgactgtgcc aattctactg ccaatatttc
     4561 agttgtcaat tgtgtctgta aatatccttg catatcaagt ggatctgcgc catcgataaa
     4621 cgattcataa aaactgacaa cacttacaac ttgtaaagca tctagatcat cataatctaa
     4681 atacgctagt gtgatttgat tgttcatcta actcctcctt ttgacatagt atactataaa
     4741 t
//
LOCUS       DADGKS010000152         4655 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.158, whole genome shotgun sequence.
ACCESSION   DADGKS010000152 DADGKS010000000
VERSION     DADGKS010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4655
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.158"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(34..714)
                     /locus_tag="JXV47_002940"
                     /pseudo
     CDS             complement(34..714)
                     /locus_tag="JXV47_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
     gene            complement(1036..1257)
                     /locus_tag="JXV47_002941"
     CDS             complement(1036..1257)
                     /locus_tag="JXV47_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488912.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            complement(1355..1600)
                     /locus_tag="JXV47_002942"
     CDS             complement(1355..1600)
                     /locus_tag="JXV47_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488913.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
     gene            1840..2454
                     /locus_tag="JXV47_002943"
                     /pseudo
     CDS             1840..2454
                     /locus_tag="JXV47_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(2824..3825)
                     /locus_tag="JXV47_002944"
     CDS             complement(2824..3825)
                     /locus_tag="JXV47_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HAX1488914.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLAIFGHKLGSPVDNYRSGTIAEIDY
                     FYKNSKGEVGVFFLDEPVPQVLAEEYIEVKKYRDSLEDKGFYGTYSKDNIRRFLTKKV
                     NYLIEKAQNNLESKRFDLDSISYKTPSVINKKVTGTDKDFDDNLDIFDPIEFDNDERL
                     LLIYAFMDENSIFSTDNSTYRKVVQWESDNNLRSYLSDRVFDVLEKLSKSGILKEEYD
                     SSFDEYPSRYILISEDYKKFKRYFLKNEKKISVIMEKYKAPIQADPFSNLDESDLPF"
     gene            complement(3984..4250)
                     /locus_tag="JXV47_002945"
     CDS             complement(3984..4250)
                     /locus_tag="JXV47_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1488915.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            complement(4240..4596)
                     /locus_tag="JXV47_002946"
     CDS             complement(4240..4596)
                     /locus_tag="JXV47_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAX1488916.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
BASE COUNT         1444 a          862 c          646 g         1703 t
ORIGIN      
        1 aatcaaacgc gccctctctg aactccaaat atcttaggct gttattccca ttaatacctt
       61 gatttcagta gacaccgaaa agccgaagag cgttccattt cttcggttct ttttatatat
      121 tcctcgaatg gtctccatgc ccttaatcgt ggaagaggct gtacggagac tttgataaaa
      181 tttatttcgt cgtttaatag gtcgatggtc ttgttctatt aaattgttaa gatacttcac
      241 agttcggtgc tctgtcttag tatataaacc cacactctgt aactttctaa aggcggagcc
      301 aagagaaggt gctttatcgg tcacaattgc tttcggctca ccaaactgtt tatggagtcg
      361 ttttaagaaa gcataggctg cttgcgtatc ccgtttcttt cgtaaccaga tatctaaggt
      421 taagccgtcc gcatcaattg cacgataaag ataatgccaa cgtcccttaa ttttgatata
      481 ggtttcgtcc attttccatg aatagaagga ttgtctattt ttcttcttcc aaagataata
      541 gaggactttg ctgtactctt atacccaacg ataaatcgta gtatgacaaa catttattcc
      601 acgatcatat aacaattcct gaacttcacg atagcttaga ttgtaacgca ggtagtaacc
      661 aacagcgaca ataatgacgt cttttttgaa ttgtttgcct ttaaaatgat tcattactct
      721 gtcctctctg tcttttttct caattttaca ctaaaataga ttttttggaa aactttgcaa
      781 cagaaccgtt tttactatat acttcttccc agaacttgtc cgtctccttc aaattatctc
      841 tacctctcga gttcattggg tggtttgccc atttattaaa catggaatca cctttctcat
      901 actcatatat ttatgtccta tttcaattat atttatatat gcttaaataa atttgtatcc
      961 tgaaatttat tgtaatatga agctgtattt tacatatagt aaccaaagag ttaataaaat
     1021 aaaaagagcg aaccattata gatcagctct tttttcattg ctgtttttaa tcttatctag
     1081 aatcacttca aatgtttcaa aggtatttac atctaactga cataaccaaa gcaagtactt
     1141 cttttctttg taagtccaat caatattacg gtaagaggac attagattat ggtaccttgc
     1201 tctttgttca actgaagcca attcccagcg tttttcaaat attttttctt cttccattat
     1261 tgatccctcg caagacgcta cctcaaactt aaataatggg cagcgaaagt ctaattcctt
     1321 agatctaagt atagcaaaca aatatgaaaa aaacttagaa ggtagtaaaa gttcttccgt
     1381 cttttgcttt gcttctattc ttaatgtgtt tcgttatcgg tgccctacaa agattttcat
     1441 taattacaca ctcatttatt gttgtgtatt ttctgacatt tctctcttga tcaattattt
     1501 taattccatg ggcatcctga tagttcatag gagaggagcg gctatcagaa atagttgcac
     1561 ctatctcttg aacttctttt acaacttctg gaaaatccat ccatcctgct tcagctgtca
     1621 aaagtaataa tctataatat ttatctttcc ttttcaatct aagaaatcgt caccccattc
     1681 tttttcttct attataaact atttaacttt tagaattcaa aaaccgtttg tctatttaga
     1741 gtttacccta aatagacaaa aatataacat tgaaaaattt agagttctaa cgtatgatta
     1801 gggtgtatta taaacgttat agaaaagtag ggaataaatt tgaaaattgc ttatattaga
     1861 gtttcatcca tcgatcaaaa tgaacaacgt caaattgaag aaatgaaaaa gtttggcgct
     1921 gaaaaaattt ttatcgaaaa acaatctgga gcgacgatta gtcatcggcc gattttccag
     1981 gaagctttag attttgtcag agagcaagat atttttattg tagaagccat tgatcgactt
     2041 ggacgcaatt atgacgagat tatcgattca gtgaattatc taaagaagaa gaatgtgcga
     2101 cttattatca ccagtttacc gatcatggct gaagcaattg gaaatcctct cctagataaa
     2161 ttcatcaaag acttaatcat ttaaatctca gccatgattg ctgaacaaga acgtactgaa
     2221 tcgaaacgac gccaggcaca aggaattaaa atcgctaaag caaacggcgt ctataaaggt
     2281 cgtcctaagt tatacagtgc agacaccaaa gatcctcaac gtcgccttgt ctataggagt
     2341 atcgttcagg atcttgagaa tggggttgct atctcaaaga ttgcaacaga ctacaatgtg
     2401 actaggcaaa caatttaccg aataaaaaaa gaaatcgacc aactaattgt atgatttctt
     2461 ttttgaatca cgtaattatt aattagcttt gtcatcaata cagacaatca ttttagattc
     2521 atctagctaa gttgattaca tttatgttaa aaagaattta gttaacataa atataattga
     2581 tgcataaatc gtccttattt aaaggcattt aacattgaca acttagtata atgtatctta
     2641 tgtaaactaa taagatttga attttatttt atacacactc gataatagat caattttatg
     2701 gtcccccgca tttacgattg cacaagagaa acataaagtc gacctattag catttctttt
     2761 caattcaaac attaaaaaag tttatacctc tgctactaaa aaatgaaatt atctatttaa
     2821 aatttaaaac ggtaaatctg attcatccaa attggaaaat ggatcagcct gtattggagc
     2881 tttgtatttc tccataataa cagatatctt tttttcattt tttaaaaaat accttttaaa
     2941 tttcttatag tcctctgaaa tcaaaatata gcgtgatgga tactcatcaa aagaagaatc
     3001 gtattcttcc tttaaaattc ccgatttact taatttttct agtacatcaa atactctatc
     3061 actcaagtaa ctccttaaat tgttatcact ttcccattga actacttttc tataagttga
     3121 attatcagtt gaaaagatag aattttcatc cataaacgca tatattagca gcaatctttc
     3181 atcattgtca aattctattg gatcaaaaat atctaagttg tcatcaaaat ctttatcagt
     3241 tccggtaact tttttgttaa ttactgaagg tgtcttgtaa gaaatagaat ctaaatcaaa
     3301 gcgttttgat tctaaattat tttgtgcttt ctcaattaaa taattcactt tttttgtgag
     3361 aaaccttctg atattgtctt tgctatatgt tccataaaaa cccttatctt ctaaagagtc
     3421 cctgtacttc ttaacttcta tatactcttc agccaaaact tgtggaactg gttcatctaa
     3481 gaaaaaaacc cctacctcgc ctttgctatt tttataaaag taatcaattt ctgctatagt
     3541 tcccgatcta taattatcaa ctggagaacc caacttatgg ccaaaaatcg ctaataatat
     3601 atcactattt tctacaattt gtttattaat aacactttgc ccagagctat tatttatata
     3661 agtaggaatc gcattcgttt cccatcgaat tggcatcaaa attacttttg tattatctgt
     3721 attttctata ttccatctat atatggtttc ttctacttca ttcctctttg ctgctatatc
     3781 acctggtgat gctataaata cttttattag atttatggtt ttcatttatt gtacctttct
     3841 ctttatgtct ctttaaagta atttttgtat aaaatttatt gacttttaca ctataggaca
     3901 acttttatct atttagtaca aaaaggccca ctaaactaat tgattagtta ggagcctatt
     3961 acaggtatat tttcaactcg cttttaagca aattctacta ccagcttttt gcctaatgcc
     4021 ctagcgatat catcaagttt atcgaaagat acgttatccc ctctctcaat tcgagcaata
     4081 gtagattgag ttgtatgtgc tttttgtgca agctccgctt gagttaggcc tgcttcctcc
     4141 cgtgcatgat aaagagcaac cgcagtttcg agttttcttc cttcacggtc atatgcttct
     4201 gcaaaatctt tgtctttttg cttttcttca atcaattttt taatcatcat ttgtgaacca
     4261 ctcctctcta agttcttttg catgtttaag ttcacttatt ggtgttttct ccgttttttt
     4321 agtaaatcca tgggtaatga cataccttcc attgaccaca tggaaataga tagctctttg
     4381 gatgtttgat cctaccttac ttcttaattc gtacaaatta gtgtctaatt ttttcaccca
     4441 tttcaaccgt tgagctacta gcatcccatt cttttctgtt tcttctattg tacgtaaaag
     4501 cttcgcacta tctttttttg gtaatgtttc caaccattct aaaaattcat catgaccatt
     4561 aggtctttta aatgtttcaa aagatatttt ttccataccc aattatatca tatattgatt
     4621 ttatattata gtatataaca taaaaattcg aatta
//
LOCUS       DADGKS010000153         4591 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.159, whole genome shotgun sequence.
ACCESSION   DADGKS010000153 DADGKS010000000
VERSION     DADGKS010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4591
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.159"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..612
                     /locus_tag="JXV47_002947"
     CDS             <1..612
                     /locus_tag="JXV47_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAX1488917.1"
                     /translation="FEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATD
                     TQYYLKLNELIKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLD
                     MAATQGEPIHAVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQ
                     GQIIGYVGSTGNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            961..1593
                     /locus_tag="JXV47_002948"
     CDS             961..1593
                     /locus_tag="JXV47_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HAX1488918.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            2181..3620
                     /locus_tag="JXV47_002949"
     CDS             2181..3620
                     /locus_tag="JXV47_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAX1488919.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            3915..4133
                     /locus_tag="JXV47_002950"
                     /pseudo
     CDS             3915..4133
                     /locus_tag="JXV47_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174271.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            4382..>4591
                     /locus_tag="JXV47_002951"
     CDS             4382..>4591
                     /locus_tag="JXV47_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488920.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIW"
BASE COUNT         1476 a          717 c          979 g         1419 t
ORIGIN      
        1 tttgaagatt atgccaaatt attaactaag ggaattagtg gaaataaaga tttttatgca
       61 ggagcattaa aagctaatag taaaacatat cgagaagcaa ctaaattcct tacaggacgg
      121 tatgcaacag atacacaata ctatttgaag ctaaatgaat taattaaaac ctacgattta
      181 accaactatg ataaagaagt taaaggtcca caaatgagta agactggata ccaagtgcct
      241 attcataatt attcaataac cagtttgttt ggaaatcgtg gaaatgaatt tcaccgagga
      301 cttgatatgg cagctacaca gggtgagccg attcatgcag ttaaagctgg taaggttgtt
      361 aaagcagagt ttcactactc ttggggaaat tacgtggtga tacaacacga agatggatca
      421 accgcgttat atgctcacca gcaacaatac ctagtaaaaa ctggagataa tgttttgcaa
      481 ggacaaataa ttggctatgt aggaagtact gggaatagta ctggcccaca ccttcatttg
      541 gaaatttgca aagatagtag tctttctcag agcatgttag ttgatccgaa aaccttatta
      601 ttcggagact aaaaaaggta atcaatctga caaagtaaca agaaaatggt tggattctta
      661 gacctttgat caggatattg agactggaat tgatatctcg attacgatgg gtttgacaaa
      721 taaaacaagt ccattatcga atatcgagtg tattattgcc gtctttatgc tcatattttg
      781 agcaggtttc actagatgaa aacaatttat ctatcttgag gatttcgtgt acgtatcgtt
      841 cagtcttgta ttgtaaatta gtcataaaat cagactaaga aaaattggaa atattttttt
      901 ctgatttatt aaaagttaat tgaaattata tggtacttct ttcttgggag ggtaggtgca
      961 gtgaaggaaa gatatggtca ccttactgtt gttgaggaga ttactcataa tggatataaa
     1021 aaatatcgtt gcctatgtga ctgtgggaat gaaacgattg tatatcgatc aaacttacta
     1081 tcaggtagaa ccaaaagttg tggatgtgga aattataaaa ataggcataa atataaaaat
     1141 ttgacaaata aaacttttgg taagttagtt gcaatcaagc caactaaact gcgaagtgaa
     1201 ggaactgttg tttgggaatg tcaatgtctg tgtgggagaa aaaagttagt atcggcaaag
     1261 cgacttctaa aaggtgatgt aaaaagctgt ggatgtttga aatcaaaaaa gcatcacatt
     1321 gaaaataaaa aattcggatt acttactgca aagtatcctt tggacaataa ctgttcatgg
     1381 aaaacaaaat gggtttgtca ttgtgagtgt ggcagtatgt gtgagataag ttatagtaac
     1441 ttattttttg gacatactca aagttgtgga tgtttaaaaa ggcaagaaac aaggacatgt
     1501 gttgaaggga cagtaataga gtgtctaacg tcaaaattac cgaaaaataa tacaagtggt
     1561 gttaagggag tttatcgttc taaagagaaa tagattgcgt atataacttt aaaaaaaaag
     1621 aggtactatt taggatcgta tgattctatt aagagtgcag ctcaagctag aaaagatgct
     1681 gaaaataaat tgtttcaacc tttgattgac aaatatcgag gtaatcatta attattgtgg
     1741 ataataatta acagtgatat ataaacatct ataatatatt attcatacta ttgatattta
     1801 gtataatcct atggaattga atatcatagc aatgtatttg aaaagcaaat tggaaaacaa
     1861 ataggtgcaa caccataaat atgaaaaaat tgggaaaaag tagaatggaa atttgcttac
     1921 gtctcacgag atagctcaca ctattaatct gaagaacaat gaagtcgact tttagaaatt
     1981 gctagaagaa agtaaagcga attatcacta gttactatag agtaagttca aataaagcat
     2041 ctccaactta catggttaca tgaggatatc aaatcgaaat tactcaagct tcctatggct
     2101 agagtcgcga gaagttgttg ggcagtagac ataggttata ttgttcttag ctacacgatc
     2161 attagaaagg aaatcctatt atgtatagtt atcaagaaga tgcaaaagtc caaaaaaatc
     2221 gctggtggat tttgattgct atatctatgt ttaccttcat gtccacattg gatggcagta
     2281 ttgtcaatat tgcactacct accatctcag atgatatggg cataccaatg aatcaagcgg
     2341 aatgggtagt gtccgtttat ctgatgattg tctgttcttg tttgttgctg tttggtaaaa
     2401 ttggcgatag ccgtgggaaa atcaaagtat ttcggattgg tacgctgatc tttgtcttgg
     2461 gatcgctgtt gtgtgggttc aatcattcgc taggtatttt attgttcgca cgggtggtac
     2521 aagccattgg tgctagtatg actatggcta caaatgccgg aatcatcacg gaagtctttc
     2581 ccatacatga acgtggtcgg gcattgggag caataggtgc gtttgtttca ttaggctcga
     2641 ttgctggacc aggtcttggc ggcttgattt tgtcccaatt ttcttgggcg tacatttttt
     2701 ggatcaatgt accggtggga atcgtaacga tgttgattgc tgaaaaattc ttaccaaaag
     2761 atatcaccat gagcggccat acaatcgatg gagggggctt tgctgccatt gcggctacga
     2821 ttatcagctt ttttggagca atctttttgg ggcaagaaag tggctttttc catccagtcc
     2881 cccttgtact gttcgtaatt tcagtgattg cctttgtcag ctttttaaaa gttgaaaaga
     2941 aagcagcctc tccattgatt tctttcggta tttttaagaa caagattttt accatgagct
     3001 tgattacagc cttgttgatt ttttcttcca acttctttgt caatgtagtg attccttttt
     3061 atctgcaaaa tgctcgcggg ttgagtccta gctatgctgg gctgttgatg atggtctttc
     3121 ctttgatgat ggtcgtcggg gcgcctttaa gcggctacct gaccgaccgg gttggcccgg
     3181 agattttggt attagtaggc ttgggcttat tgtcggtaac ccaggtcatg tatatgtttt
     3241 tgtcagtgga ctctcctttg tggctataca ttgtcgctac tgccatcatg ggtgccggca
     3301 atgccttgtt ccagtccccc aataatacga tggttatgag ctcggtcact atcgaaaact
     3361 tgggactggc aggctcgatg aattcctttg cccgaaattt ggggatggtc agcgggattt
     3421 cgctttctac gacggtctta tatcaagcga tgtctgctaa gatgggccag caagtaacta
     3481 actatatcgc aaatcggccg gatgtctttt tatatggaat gaagattacc tttttaggca
     3541 gctttgtttt gtgttttgtt gcctttttcc tgactatctg gcgtatcaaa aaacaaggag
     3601 gtattcagaa aaatgtctga aaaaaccact gttgaagaat ttttggaggc ctgcgtatgg
     3661 gtgagtggga tttccatgga tgatggaaga tgaagtgaac ttctaaaagc cgaaaaactc
     3721 aagtattatc ttcaaaatac tagtgctcaa tgagatgctt gatttgatca caagaagact
     3781 gcgaaagccg ctggcaaccg caagctaggt atcccaccga tggactacgt tttagaggct
     3841 actggttatg aatacggagc caacgctctc atctgcataa gaatacatca cccagattat
     3901 gtaaagattt tcgatacttc tgtcaaaaaa tcattaagat agataaatga tttccgtcta
     3961 gtcaaattgg ttcagaatgt agacacacag atggtaagaa gtcactcaca attcgagaat
     4021 ggacttgtcc tatttgccgt atacatcata atcgaaacgt caacgatagt atcaatattt
     4081 tgaccaaggg ctatgaatac aagcattgcc ttagaaaaca tcaagaacct taggaacaac
     4141 ggggatagct tggttaataa gagataccgc tgtttaggct tgcaagtata ctcttttatc
     4201 aagaattccg tggctttagt catgagaggc ttaatactat gaaaattttc tttagcattt
     4261 ttgatttagg ttccttttct aattataata agatgaccac tacagtaacc tactgaaata
     4321 tataaacagc cactgtagta ccattttcaa agtagtctat gagaggagaa tcttcattct
     4381 tatgaacgct ggaattgcgg atatgaattt aataaaaaaa acccttaatg attttacttc
     4441 caattcaata tcaaaaggta ctggtatcaa tttaagcaca ataaaaaagc tgaaaagtgg
     4501 tgaaagatca gtggaaaagc tgaatctttt agatgctata aaaataacgg aatttgctat
     4561 gaaaaatgga aaagctgaga ttgaaatatg g
//
LOCUS       DADGKS010000154         4586 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.160, whole genome shotgun sequence.
ACCESSION   DADGKS010000154 DADGKS010000000
VERSION     DADGKS010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4586
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.160"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            186..2855
                     /locus_tag="JXV47_002952"
     CDS             186..2855
                     /locus_tag="JXV47_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAX1488921.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEVSFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEKPRNTHRRRRRK"
     gene            complement(2946..3566)
                     /locus_tag="JXV47_002953"
     CDS             complement(2946..3566)
                     /locus_tag="JXV47_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAX1488922.1"
                     /translation="MFLINATDEILSVNKVFYTVPAEKMSRVSSDINTITSRIGLTKA
                     MHMVLKYNQEDPPVPKTYEAIDLIIVDEIDRLKLQHLEQLRDIYDRNDLAMVLIGMPG
                     IEKRLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWADLGIDIKLEDFSDYEAITTI
                     IKITKGNFRLIHRLFAQIDRILRINQMDKITVEVVEAARDSLVIGI"
     gene            3679..4218
                     /locus_tag="JXV47_002954"
     CDS             3679..4218
                     /locus_tag="JXV47_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488923.1"
                     /translation="MKKLFSALFILLFGFIGIGTSGNIVKASTMVEQTSEMAKTFSQL
                     TPEEQSYFKSKGFSDKDTFYTQKIEPQDPKTRFSANVLRLTASTKKITNTQGRTEYII
                     TSPNSAMYRISTRLSLGSAKSYTQTVNLANSYGYGGGMYFTFTGKRQYYSVKLAMQVY
                     NTFGVGSVSCTAGGLTIGK"
     gene            4215..4553
                     /locus_tag="JXV47_002955"
     CDS             4215..4553
                     /locus_tag="JXV47_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic metallochaperone ArsD family protein"
                     /protein_id="HAX1488924.1"
                     /translation="MIISYYVLNRSDDEGLFVFQSLHEDTMLKEFYNRIKNKQIETNL
                     YFLSDSILPFISNPKILNLLQTKDLKSLPIIVIDEEIVKYGAYLSVEELEKLTNIGMS
                     IQEDNGVHGT"
BASE COUNT         1418 a          790 c          860 g         1518 t
ORIGIN      
        1 atttttaagg gtgggacttt tgattcctac cctttttttg cgtttatttt tgttatacga
       61 acaaattatg aagttattta ttctaaattt tatttttttg tgaaaattag actcttttta
      121 agcagagaaa aacaaggata tgataaactg aatacaactt catagaaatt tggtggaaaa
      181 taaatatgaa aaaaaattta aagtcattct ttagagaaaa cggacgctac gcagcagcta
      241 gtttcctgat tccgtttttg attttagcac ttgtttatct aagtatcggg atctatcctg
      301 gaagcagcag aagtattttg gcaagtgatg ccttttcaca gttttctaat tttcatgcca
      361 gcttccgaaa tgttcttctt ggaaagcaaa gtatttttta tacatggaat gcttctctag
      421 gattgaatta tttatcttta atttcttact atctaggcgg gatcttcacg ccactggtgt
      481 tcttttttcc aaaccagatg atgccagatg cactgtatgt tctgactttg cttaaggtcg
      541 gctgtgccgg attggctttt tggtttcttg cacgtacgtt caagattcct cgctgggggc
      601 atgttgcact tagcgtcagt tacgcattga tctcatttat cactgcacat tcggagatca
      661 tcatgtggct ggatgcattt gtttatcttc cattagtgat tttggggatt catcgtgtta
      721 tggatcttaa acggccgaaa cttttattta tcagttattt actcttgttt ttatccagtt
      781 tttatatggg ttttatgatt ggcgtatttt ctttcttata ttttatcgcc cgtctattga
      841 caaactggtc agaatataaa aaaacgattg ttccttatgg tatcacttct ttactggcag
      901 gcggcgcttc aatgatcatt gtattgccag cagtgctgga tcttcggtca aatggcgagg
      961 cactgagtca gatcactacg ttgaaaacag aagcgacttc ttatctggat ctaatcatga
     1021 aaaatatgat tggtgtttat gacacgacaa aatacggatc gattccgttc gtttacgcag
     1081 gtctgctacc attagtcctc tgtctgtttt attttgccag tcggaaagta ccgttgaaaa
     1141 ataaattttt gtacggcagt cttttcgcca tacttatcgc aagtttctat cttgttccat
     1201 tgaatttgtt ctggcatggt atgcatgcac cgaatatgtt tttattccgt tatgcctatc
     1261 tgttctcttt cttagtgctc ctgcttgcag gaaaaggatg ggaaaagata gaacaagacg
     1321 atcgtgggct gttgttagga atcattttgg tcgtagctgc tctctttgcg gtggcatggg
     1381 gcatcaaacc tgaaggaagc tacacctatg tgacgatgac ttcctttgta ttgacagtgg
     1441 ttttcttagg gatttatgct tttgctgtgg gattttatca gcataaaaaa ctttcattca
     1501 atcatctgag tatattgtta ttattgatca tgtctgctga agcactggtc aatacgaaca
     1561 gtatgatcca tggcattctt gatgattgga attatgcttc ccgcagttta tatactgatc
     1621 cttatcctga cttgaaagct cttgtaaatg aaacaaaaaa agattccgac tcgttttacc
     1681 gcttggaaaa tctggatcca gtatctgcaa acgattcgat caactatggt tacagtggta
     1741 tcagtttgtt ttcttctata agaaatcgta attcttcctc ttacctggat aaattaggtt
     1801 tccgttcaag agggacaaat ttgaatatcc gttataacaa taatactttg ctaatggatg
     1861 ggtttacagg aatcaaatat aacatttcta aaaacgaaag cacgttcagt aaatatggct
     1921 tccgccaagc tggtcaaagt ggcgactata cactgtatca gaatgtcaat gcattgccac
     1981 tagcatttac tgcaccgttg tccgttaatg atgttgagca gccagtgaca gataatttga
     2041 ccagtcagac aaacttgatc aatacattgt ctggtttaaa tgaacagtat tttacattct
     2101 atacacctac tttgaagaat cagttgaata cgacgatcac aaagacaacg actggcgtca
     2161 cttactcaga aacagcagat aaccagccaa aagagctcac ttgggaagtc catgtgcctg
     2221 caaatacaca agcttactta agtttgttcc caaccaattt tgcacaatta gaaagttcta
     2281 gtgcgacgat cactgtcaat ggtacatcgc gaaaaacgca aatcaacatt tctggtcaat
     2341 actatgatct tggctattat cctcaagaga caacagtgac atttactgca agtttttatg
     2401 gaacgaaaga agtaagtttc atggagccta aagtcgttgg tctagatgtt gtagcctatc
     2461 aagccgcaat gaatcagatc aaagaaaaag gtgtcgaaat ggaagccact ggcagaaaag
     2521 cttctgggac tgtaaatacc gctgaagatt ccatgttggt gacaactatt ccttatgaca
     2581 aaggatggaa agctaaaatt gatgggaaac cagtcaaggt cagcaatttc aaagacgcat
     2641 tcttgatgat aaaagttcca gcaggtaaac atactgtcac tttcagttac ttgcctgaag
     2701 gatttacgat aggtgcaatc ctttttgtcc tatgtattgc attgtttatt ctttatgtct
     2761 ggtaccttga ccgcaatcgc cccttttatg gcacgattga tccagcaata gaagaaaaac
     2821 cgcgaaatac acacagaaga agacgaagaa aataaagaaa cgatggaatc tgtgtcactc
     2881 ttctatttaa atggcaaaaa tttcaatctt taaatgacaa aaaccacctg atttttggtg
     2941 gttttttata tacctatgac taaactatct cttgctgctt cgacaacttc tacagtgatc
     3001 ttatccattt gattgattct taaaatccga tcaatctgcg caaataaacg atgaataagc
     3061 ctaaaatttc cttttgtgat cttaatgata gttgtgatag cctcataatc agaaaaatct
     3121 tctagcttga tatcaattcc taaatctgcc catttgtatt ccaaaatatg atgtgtttcg
     3181 tccttactaa ggttatcaaa ttcatgtgca aatcctatgc gagagtaaag ctgcggataa
     3241 cgagacaatc ttttttcaat accaggcata ccgataagaa ccattgccag atcatttcta
     3301 tcgtaaatat ctcttagctg ttctaaatgc tgaagcttta aacgatcaat ttcatcgaca
     3361 ataattaagt caattgcttc ataggtttta ggcacaggag gatcttcttg attgtatttt
     3421 agtaccatat gcattgcttt agtcagacct attctactag ttattgtgtt aatatccgaa
     3481 ctgacacgag acatcttttc agctggtaca gtataaaaaa ctttatttac acttaatatt
     3541 tcatctgttg catttatcaa gaacaagaaa aagtctgaat attcaaaaaa ataacggtgt
     3601 acatttttaa aaggagatgt ataatcgaga tttagaaagc gttttcctca aaatttaatg
     3661 aattaggaag tgattactat gaaaaaatta tttagcgcac tttttattct gttatttggc
     3721 tttattggta ttgggacttc tggaaatata gttaaagcta gcacgatggt tgaacaaaca
     3781 agtgaaatgg caaaaacttt tagtcaatta acaccagaag aacaaagtta cttcaaatcc
     3841 aaaggattta gtgataaaga tactttttac actcaaaaga tagagcctca agatccgaaa
     3901 acacgttttt ctgcaaatgt attgcggtta accgcatcta ctaaaaaaat tactaatacg
     3961 caggggcgga cagaatatat tataacaagt cccaattcgg cgatgtatcg tatttctaca
     4021 cgcttgagtt taggtagtgc aaaatcatat actcaaacag taaatctagc taattcttat
     4081 ggttatggtg gaggaatgta ttttacattt actgggaaaa gacaatatta cagtgtaaaa
     4141 ttagctatgc aagtttataa tacatttggt gtagggtcag tctcttgcac tgcgggagga
     4201 ttgacaatag gaaaatgata atttcttact atgtcttaaa tagaagtgat gatgaaggac
     4261 tcttcgtttt tcaatcatta catgaggata cgatgctaaa agagttttat aatcggatta
     4321 agaataaaca gatagaaaca aatttatatt ttttaagtga ctctatcttg ccttttatta
     4381 gcaaccctaa aattcttaac ttgttgcaga caaaagattt gaaaagttta ccgattattg
     4441 tcattgatga ggaaattgta aaatatggcg cttatctaag cgtagaagaa ttagaaaaat
     4501 taactaacat tggaatgagt attcaggagg ataatggggt acatggaaca tagaatgaat
     4561 atgcacagtt gagaacggaa tttgac
//
LOCUS       DADGKS010000155         4548 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.161, whole genome shotgun sequence.
ACCESSION   DADGKS010000155 DADGKS010000000
VERSION     DADGKS010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4548
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.161"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            260..460
                     /locus_tag="JXV47_002956"
     CDS             260..460
                     /locus_tag="JXV47_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488925.1"
                     /translation="MLKRIAWDKDNKTDIELKEYKYNYFSRCIDRKLLFKKEGLEFSF
                     DEDEFEKLVMDWRKNLLDTVQF"
     gene            594..1820
                     /locus_tag="JXV47_002957"
     CDS             594..1820
                     /locus_tag="JXV47_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488926.1"
                     /translation="MIFYMFININEVLKLTTITMTKKIEVYVDGSQEERDSFFDFFWK
                     NSREYVKALNLVYKQLMFEELIKDAIKEMDQGYAEREESIQNRIEKLAYTDPIDQKKL
                     DKAKAELSKLRNEKNKEAREILTQAIGLKSQTRTRDVAKKLDFDFGDFVDSANMKASK
                     DFGNDFIGIVTGQRTPRIYKNRNKYGLLPFRGRDIKIHKDDKFYIYLPKGFRFKVNLG
                     SKPRKARDVASVLQHIMDGDYKLNQSNLIFDGRKLFFNLTISFEKSYNEMEFKKGNEL
                     IVNFADLCSGECLINDKSVMSFGDSQYIRNFKSKILAMKSKEQSRGVFSKGGHGRKRK
                     LDQDRWEAIKKRESNFVKTYNNQCSAKIVKTAIRNKAQIIRIIEPDKAYGEWAYYQLK
                     EQLVNKGKRYGIEVRS"
     gene            2670..3995
                     /locus_tag="JXV47_002958"
     CDS             2670..3995
                     /locus_tag="JXV47_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAX1488927.1"
                     /translation="MFDYSREPVNDYFLIDMKSFYASVECIERNLDPMTTPLIVMSRS
                     DNTGSGLTLASSPTAKKKYHITNVSRATDLPYPLPKELHIVPPRMNLYIKKNMEVNQI
                     FRKYVADEDLLIYSIDESILKVTKSLNLFTSSGTRSERRRELAKIIKDEIQKETGLIA
                     TVGIGDNPLLAKLALDNEAKSSKEFIAEWTYETVPEKIWKINEMTDFWGIGSRMKKRL
                     NHMGIMSIEDLANWNPYTIKSQLGVIGLQLYFHTNGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPKDYTRREEVELVVKEMAEQVAIRIRQHNCKTGCVRLAIGTSILEEKSGFSHQMKI
                     PITDNTKELQNYCLFLFNKFYEGQEVRHIGVTYSRLVYTDSLQLDLFSDPRKKIAEEN
                     LDRIIDKIRQKYGFTAIIHASSMLEGARSITRSTLIGGHAGGLGGLHND"
     gene            3988..4335
                     /locus_tag="JXV47_002959"
     CDS             3988..4335
                     /locus_tag="JXV47_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488928.1"
                     /translation="MIEYNDRGRLKWSGFYLSDHTERINADNVQRANHNLAKEQMTTE
                     EIAKILRTAVIKNRPVCIQKEERNAEGYYPDDVVGKIIGYDELGVFVEEEKVHYDEIR
                     NVSFSELLKWSQI"
BASE COUNT         1762 a          558 c          863 g         1365 t
ORIGIN      
        1 gcttttgatt gaattagtat caagtcttag tagttttgga aaaatgaaaa gatttaatgt
       61 gatattagaa atttttgctt ggttaatccc ttcatttatt tggttttttt atattttcat
      121 agttgaatct gagttaatag ccaaggtctc tcttggactg ttaattccga tataaatagg
      181 ttcagcaatt tactttaata acttgtatac acgtattcaa ataaaaaagc agttattaca
      241 tgaaggatta agtggtaata tgttaaaaag aattgcatgg gataaagata ataaaacaga
      301 tattgagctt aaagaatata aatacaatta tttctcgaga tgtatagata gaaagttact
      361 gtttaaaaaa gaaggattag aatttagttt tgatgaagat gaatttgaaa aattagtgat
      421 ggactggcgt aagaatttac tggatacggt acaattctaa aagcaattga ggtcgaaatt
      481 ccgatacttg aatcatgatc tatattatcg tgttatgagt gaaatttcta ataaagataa
      541 gatatttcat ttggacagtc atgtgaatat gagcttaaca attaaacgta tttatgatct
      601 tttatatgtt tataaacatt aatgaggtgc taaaattgac aacaataact atgacaaaaa
      661 aaatagaagt atatgttgat ggatcacaag aagaaaggga ttcctttttt gatttttttt
      721 ggaaaaatag tagagaatat gtaaaagcgt tgaatctggt atataaacag ctaatgtttg
      781 aagagttgat aaaagatgca attaaagaaa tggatcaagg ttatgctgag agagaagaaa
      841 gtattcaaaa tcggattgaa aagttagcat atactgatcc aatagatcaa aaaaaacttg
      901 ataaagcaaa agctgaatta tctaaattga gaaatgaaaa aaataaagaa gcgagagaaa
      961 tattaacgca agcgataggg ttgaagagtc aaacgagaac acgagatgta gcaaaaaaat
     1021 tagactttga ctttggagat tttgttgatt ccgcaaatat gaaagctagt aaagattttg
     1081 gcaatgattt tatcggaatt gtgaccggac aaagaacgcc tagaatatat aaaaatagaa
     1141 acaaatatgg attactacct tttagaggtc gagatattaa aatccataaa gatgataagt
     1201 tttatattta tttacctaaa ggctttaggt ttaaagtgaa tttaggtagc aagccaagaa
     1261 aagcaagaga tgttgcttca gttttacaac acattatgga tggcgattac aaattaaatc
     1321 aaagtaatct tatttttgat ggaagaaaat tattttttaa tctaacaatt tcttttgaaa
     1381 aaagctataa tgaaatggaa ttcaagaaag gtaatgaatt gatcgtaaac tttgcagatt
     1441 tgtgtagcgg tgaatgttta attaatgata aatctgtaat gtcttttggt gatagccaat
     1501 atataagaaa cttcaaaagt aaaattttag caatgaaatc aaaagaacaa agccgaggag
     1561 tcttttctaa gggcggtcat ggtcgaaaaa gaaaattaga tcaagatcga tgggaagcaa
     1621 taaagaaaag agaaagtaat tttgttaaaa cttataataa tcaatgttct gcaaaaatcg
     1681 ttaaaactgc tattcgcaat aaagctcaaa ttattcgtat cattgaacca gataaggctt
     1741 atggcgaatg ggcttactat caattgaaag aacaactagt aaacaaagga aaaagatatg
     1801 ggatagaagt cagaagttag taaattaaac aatcgttgat ttggcaacga aatagtgagg
     1861 gaaaatccac tcactgaagg gtaaactccg tcaagttgtg tgaccagacg gaaggacgaa
     1921 tgttgttgag gttttagaac catataaaac agcatgtttc tcaaattttt aggataaggg
     1981 aaattgctag cagtttgttt tagaaccata taaaacagca tgtttctcaa atgagtactt
     2041 taaattaatt gatggcgttc ctgctttaga accatataaa acaacatgga tttaaaacaa
     2101 gaagtaagtc agttctcctt ttactttagt aaggaaaaat aaagtattct caataaaact
     2161 taaaataagc aaacctttgt tttaatagct aatcgaagta aaacccaaag ccatatgaac
     2221 ccctgaatca gcgaaagttt atgatgattt ggattactaa tagtttagga attagatggt
     2281 aaatctaaat taaacaatcg ttgatttggc aacgaaatag tgagggaaaa tccactcact
     2341 gaagggtaaa ctccgtcaag ttatgtgacc agacggaagg acgaatgttg ttgaggtttt
     2401 agaaccatat aaaacagcat agttctcaaa ttgtttaaaa tgattgtcaa gttaaaaaaa
     2461 tctgggatca tataaaatag tatagttctc aaatatgatt agaaacccta ttaaagagca
     2521 atattaagcc aacttactta aatcgtttaa ttaagaacaa taatctcttt tagtcagact
     2581 tttagtctga cttttttgta tttccaaaat ttattcttta caaaaacgaa catacgtttg
     2641 tataattgct tgtgaatggg ggaataaaaa tgtttgatta cagtagagaa ccggtgaatg
     2701 actatttttt aatcgacatg aagtctttct atgctagcgt ggaatgtatt gaacgaaatt
     2761 tagacccaat gactacaccg ttaattgtca tgagtagatc ggacaacact ggttcaggtc
     2821 tgactctagc ttcttcacct actgcaaaga aaaaatatca tattactaat gttagtagag
     2881 ctactgattt accttatcca ttaccaaaag aacttcatat tgttccacca cgaatgaact
     2941 tatatataaa aaaaaatatg gaagttaatc agatttttag aaagtatgtc gcagatgaag
     3001 atttattgat ttattcgatt gatgaatcaa ttttaaaagt gacaaaatcc ttaaatttat
     3061 ttactagttc aggaacaaga agcgagagaa gaagagaatt agctaaaata atcaaagatg
     3121 agattcagaa agaaacaggt ctaatagcaa cagtcggaat aggagataac ccattattag
     3181 ctaaacttgc actggacaat gaagcgaaga gtagtaaaga atttatagct gagtggactt
     3241 atgagactgt acctgaaaaa atatggaaaa taaacgagat gactgacttt tggggcattg
     3301 gatcacgcat gaaaaaaaga ttgaatcata tgggaattat gagtatagaa gatttagcaa
     3361 attggaatcc ctacacaatt aaaagtcagt taggtgtaat cggactccag ttatatttcc
     3421 ataccaatgg aattgatcgt acggatattg ctattccacc agaaccaacc aaagaaaagt
     3481 cttatgggaa ttcacaagtt ctaccaaaag attatacgag gagagaagaa gtagaactag
     3541 tagtcaagga gatggcagag caagtagcca ttcgaattag acaacacaat tgcaaaactg
     3601 gttgtgtacg cttagcaatt ggtacgtcaa ttttggaaga aaaatcaggt ttctcgcacc
     3661 agatgaaaat accaattaca gataatacga aagaattaca aaattattgt ctttttttat
     3721 tcaataagtt ttatgagggg caggaagtac gacatatagg agtaacttat agcagattag
     3781 tatacacaga ttccctacaa ttagatttat ttagtgatcc aagaaaaaag attgctgaag
     3841 aaaatttgga taggattatt gataagatta gacaaaaata tggatttaca gctattatac
     3901 atgcttcatc tatgttagaa ggtgcaagaa gtattacgag aagcacttta ataggaggac
     3961 acgcaggagg attaggaggt ttgcataatg attgaatata acgatagagg acgtttaaaa
     4021 tggtcgggat tttatttgtc tgatcatact gaaagaatca atgcagacaa tgtacaacgt
     4081 gctaatcata atttggcaaa agaacaaatg acgactgaag agattgcgaa aatactgaga
     4141 actgctgtca taaaaaatag acccgtctgc attcaaaaag aggaacgaaa cgctgaaggt
     4201 tactatccag atgatgtagt aggaaaaatt attggatatg acgagcttgg tgtatttgtg
     4261 gaagaagaaa aagttcacta tgatgaaatt aggaatgttt ctttctcgga attattaaaa
     4321 tggagtcaga tatgaacatt attaaaaaat acgaattcgg ttatattacg tatgaacagc
     4381 taatagagga attatgggga tatggtcaac aattaattaa tgaagtgggg attgattgct
     4441 tttgtttcta tattgaatcc ggagcaggat accataagaa cagatactat atatttccat
     4501 atccaccaaa atagtctctt agatattttt aaattttctc caaatact
//
LOCUS       DADGKS010000156         4493 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.162, whole genome shotgun sequence.
ACCESSION   DADGKS010000156 DADGKS010000000
VERSION     DADGKS010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.162"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            175..1500
                     /locus_tag="JXV47_002960"
     CDS             175..1500
                     /locus_tag="JXV47_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1488929.1"
                     /translation="MKVVDRLSEKMLPIVSKMSSQRHLLAIRDSFIVTMPLVMAASVM
                     VLLNALIFSNATVQRILDLSPLAELASIVNNGTMSILAIIVCYNIGWNLATHYIQTGV
                     IDDPSFSPVHAGILSTAVMFILMSLSSTVTLMDGNTAEATGVFLQSLTSSSGLATAMI
                     AALVSTELFIKLAKMKSFKIRMPEGVPPAVAASFNSLVPEIVVILFFSVVVFTLNHTT
                     GLNVPQLIELAIQTPLKAFVLSVPGILFLQFFSDFLWVFGMHGSSILAPIRQAPLLQS
                     IQENMDAFSVGKEIPNIITEPFTNAFGLIGGGGCILPLVIAILWASKRQEQRSIAKFG
                     LTTCLFNITEPIMFGLPVVMNPIYMIPCAIIPSINLVIAYAATSLGIISKTVAAAPWI
                     TPPVIQSFIATGGDIRAAVLTVILIILDVFLFLPFVLAANKAKLAEGGY"
     gene            1502..3802
                     /locus_tag="JXV47_002961"
     CDS             1502..3802
                     /locus_tag="JXV47_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 3 glycosyl hydrolase"
                     /protein_id="HAX1488930.1"
                     /translation="MYDYPYQNPKLTIRQRVEDLLSRMNIAEKVGQVNQHLYGWECYE
                     KNGDKIELTEKLKEHVKWGGGLGALYGLFRSDPWSKTDYKNGIPAKESWKVANLVQEY
                     VLQHSRWKIPVLLVEECPHGHQGLDGISYPTNIGRGNTFNVALLEQSSRLMAKELAAK
                     GVHLALVSTLDLAKDPRWGRTEECFGEDPILSARFSEAVVRGFQGEIISEKVSFLDQT
                     VEEINKKKDQIGVVLKHCIAQGEALGGHNSGTVTIGRREFSDIYGPLLKSTRNAVGVM
                     AAYNDIDGIPCHINRALFEQTLRKEIGYQGIVMADGVALDRLSDVFTDKKTAAAYALA
                     AGIDLSLWDETYTKIAEAIDNQVVDEKLLDQAVRRVLSVKFLLGLFEQPFANDPKEYW
                     DHLMEESEHLNLETAKESITLLKNDGILPLDQQVKNIAVIGPNAHDVYHLLGDYSAPQ
                     TEDRLKKKIVQEIKTEFPQSKVSYAQGCEVRNQEDQEEKLLEAVTLAQNSDVIIAVLG
                     GSSARNFDMEFLRNGAVSSKGINMDSGENVDVASLSLGGYQEQLIEQLYQLGKPIITI
                     LVQGRPYDLMKIESFTNAIATAWFPGQEGGKAIAQMISGRNNPSGRLSLSYPRNSRQL
                     PVYYYQRAASKQENYYDLSGSPFYPFGHGLSYTTFEYSQMEVKTDIDKVIISIKVKNT
                     GSVSGKTSTLVYVRLIDGVVIQRTKLLKAFRKDELRSQEERLLVFELTSEDFSYMDID
                     DKRHYAKKAVIMVEQQEKEIKCNWQE"
     gene            3809..>4493
                     /locus_tag="JXV47_002962"
     CDS             3809..>4493
                     /locus_tag="JXV47_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAX1488931.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMEKISEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISNRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHAIDGLIVFLSEEEWSGFEMLTKMSIPVVALNCPGGPAGIDTIVVNDR
                     ESVAKVIAHHGGQGHKTIGFIAAAQTDYVARERLAGAKEAVQKDPSIHLEIFTGDYSR
                     KSGYYGAKAL"
BASE COUNT         1442 a          752 c         1003 g         1296 t
ORIGIN      
        1 aaacggatgg aagagaaaaa attcacaaaa taccattaaa tagaataatt tttcaaaagt
       61 cataaaaaat ccaccacctt tagaaagcgt tttaaaaaaa tgtgttgcaa tctttaaaaa
      121 aagtgctata ttaaaaatga accggttcaa ttttagaatc taggagatga aataatgaaa
      181 gtcgtagaca gactatctga aaaaatgcta ccaatcgtat ctaagatgag tagccagcga
      241 cacttgctgg ccattcgaga cagttttatc gttactatgc cgttagtaat ggctgcttct
      301 gtcatggttt tgctgaatgc tctgattttt tcaaatgcaa cagtccaaag aatacttgat
      361 ctaagtccat tggctgaact tgcttcaatc gtgaataatg gtacgatgag tattttagct
      421 attatcgtgt gttacaatat cggctggaat ttggcaaccc actatatcca aacaggcgtg
      481 attgatgatc catcatttag tcctgttcat gcaggaattc taagtacagc cgtaatgttt
      541 attttgatgt ctttatcaag tacagtcact ttgatggacg gaaatacagc agaagctaca
      601 ggggttttct tacaaagtct gacttcttcg tctggcttag caacggcgat gattgctgcc
      661 cttgtcagta cagaattatt tatcaaatta gcgaaaatga agagttttaa aatcaggatg
      721 ccagaaggag ttccaccggc agtagctgcg tcatttaatt ctttagtacc agaaatagtt
      781 gtcattttat ttttttcagt tgtcgttttt actttaaacc atacgactgg tttgaatgtt
      841 ccgcaattaa ttgaattagc gattcagaca ccattgaaag cttttgtttt atccgtccca
      901 ggcatcttat ttttacagtt tttctctgat ttcttatggg tgtttggtat gcatggttcg
      961 agtattttgg ctcctatacg gcaagcacct ttgttacagt ctattcagga aaacatggat
     1021 gctttttcag taggaaaaga aattcctaat attattacgg agccctttac caatgcattt
     1081 ggattgatcg gaggtggcgg gtgtatttta ccgttagtta ttgctatctt gtgggcttct
     1141 aaacgtcaag aacagcgatc aatcgctaaa tttggtctga ctacttgttt atttaatatt
     1201 acggaaccaa ttatgtttgg attaccagta gtcatgaatc caatatatat gattccatgc
     1261 gctattatac catctattaa cttggttatt gcctacgcag ccacaagtct tggaatcatc
     1321 agtaaaacag ttgctgctgc accttggatc actccaccgg ttatacaatc ttttattgct
     1381 acaggaggcg atatacgagc agcagtctta acagtaatac ttatcattct agatgtattt
     1441 ttattcctgc catttgtatt agccgctaat aaggcaaaat tggcagaagg aggatattaa
     1501 ggtgtacgat tacccgtatc aaaacccaaa gttaaccatc cgccaaagag tagaagattt
     1561 actttcgagg atgaatattg ctgaaaaagt aggacaggta aaccagcatt tgtatggttg
     1621 ggaatgttat gaaaaaaacg gagacaagat cgaattaaca gaaaagttaa aagaacatgt
     1681 taaatgggga ggcggtctgg gtgccttata cggtctgttt cgctctgatc cgtggtctaa
     1741 aacagattat aagaatggga ttcctgcaaa agaaagctgg aaggtggcta acctagtcca
     1801 agaatatgta ctacagcatt cgcgatggaa aattccagtt ttgcttgtag aagaatgtcc
     1861 acatggtcat caaggcttgg atgggatttc ttatccaacg aatatcggcc gtggaaatac
     1921 tttcaatgta gcattattag aacaatcgag tcgattgatg gcaaaagaac tggctgctaa
     1981 aggtgttcat ttagcgctgg tgtcgacttt ggatctggca aaagatcctc gttggggaag
     2041 gacagaagag tgctttgggg aagatccgat tctctcagct cgtttttctg aagcggtcgt
     2101 tcgagggttc caaggagaga ttatttcaga aaaagtttct tttcttgatc agacagtaga
     2161 ggaaatcaat aagaagaagg atcagatcgg tgttgtgtta aagcactgta tcgcacaagg
     2221 agaagcttta ggcggtcata attcaggcac agtaacgatt ggacgcagag agttctccga
     2281 tatttacgga ccattattga agagtacaag aaatgcagta ggtgtcatgg ctgcttataa
     2341 tgacatcgac gggatacctt gtcatatcaa tcgagcgctt tttgagcaaa cattaagaaa
     2401 agagatcggt tatcaaggaa tcgttatggc agacggtgtg gctttggatc gtttatccga
     2461 tgtttttaca gataaaaaga ctgctgcagc atatgcatta gcggcaggaa tcgatctcag
     2521 tttgtgggat gagacctata ccaagattgc agaagccatt gataatcaag tcgtagatga
     2581 aaagctacta gatcaagcag ttcgccgagt tttatctgtc aaatttttat taggtttatt
     2641 tgaacagcca tttgcaaacg atccaaagga gtattgggat catctcatgg aggaatcaga
     2701 gcacttaaat ttagagacag caaaagaaag tatcacttta ctaaaaaatg acggtatatt
     2761 gccgttggat caacaagtaa aaaacattgc tgttataggt ccaaatgctc acgatgttta
     2821 ccacttgttg ggagactact ctgcaccaca aacagaagac cgtttgaaaa aaaagatagt
     2881 acaagagata aaaacagagt ttccccaatc aaaggtttct tatgcacaag gatgtgaagt
     2941 aagaaatcag gaggatcagg aagaaaaatt attagaagcg gtgacccttg ctcaaaactc
     3001 agatgtgatc attgcagttc taggtggatc aagtgcgcgg aactttgata tggaatttct
     3061 tcgtaacggg gcagtttcat cgaaagggat caacatggat tctggagaaa atgtagatgt
     3121 tgcttctctt tctttaggtg gataccaaga acagctgatt gaacaattgt atcaactagg
     3181 caagccaatc atcacgatac ttgtgcaagg aagaccctac gatttgatga aaatcgagtc
     3241 atttacgaat gccattgcaa cagcatggtt tcctggacag gagggtggaa aagccattgc
     3301 gcagatgatt tctggaagaa ataacccaag cggacgattg agtttgtctt atcctagaaa
     3361 tagtcggcaa ctacctgttt attactatca gcgtgctgct tctaaacaag agaattatta
     3421 tgatttaagc ggaagtccat tttatccttt tggacatggt ctaagctata caacatttga
     3481 atacagtcag atggaagtca aaacggatat tgacaaagta ataatatcaa ttaaagttaa
     3541 aaatacagga agtgtttcag gtaaaacaag tactcttgtc tatgtccgat taattgacgg
     3601 cgttgtcatc caaagaacga aattattgaa agcttttcgt aaagatgaat tgcggtctca
     3661 agaggaaaga ctgcttgttt ttgaactcac ttctgaagac tttagttata tggatattga
     3721 tgacaagcgg cattatgcaa agaaagcggt catcatggtc gaacaacaag aaaaagaaat
     3781 caaatgtaac tggcaggagt gaaaatgtat ggcatcgatc cgtgacgtgg ctaagatggc
     3841 tggtgtttca gtgggaacag tttcccgcta tttaaacggt cagcagctga aggaaaagaa
     3901 tatggaaaaa atatcagaag cgatttcagc gttggactat aaagaaaaca tcattgctaa
     3961 aggattgaag aataatcgaa gtttctctat tggactgttg ataaacggga tatctaaccg
     4021 atttggttcg gaggttgttt cagggatcga aagagtagct gaagaaaatg ggtatagctt
     4081 attattaagc gggtttgccg atcagccaga aaaaatcgaa caaaaaatcg aatacctgat
     4141 gaagcatgcg atcgatggat tgatcgtctt cttatcagaa gaagagtggt ctggatttga
     4201 aatgctgaca aaaatgagta tcccagttgt cgcattgaat tgtccgggtg ggccagcagg
     4261 tattgataca atagtagtga atgatcgaga aagtgtagca aaagtgattg ctcatcatgg
     4321 cggacaagga cataaaacaa taggatttat tgctgccgct caaacagatt acgtagcaag
     4381 agaacgttta gctggagcca aagaagcggt acaaaaggat ccgtctatcc atttagagat
     4441 ctttacagga gactattcta gaaaaagcgg ctattacggg gcaaaagcat tat
//
LOCUS       DADGKS010000157         4486 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.163, whole genome shotgun sequence.
ACCESSION   DADGKS010000157 DADGKS010000000
VERSION     DADGKS010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4486
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.163"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(28..963)
                     /gene="murB"
                     /locus_tag="JXV47_002963"
     CDS             complement(28..963)
                     /gene="murB"
                     /locus_tag="JXV47_002963"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HAX1488932.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(1036..1956)
                     /locus_tag="JXV47_002964"
     CDS             complement(1036..1956)
                     /locus_tag="JXV47_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAX1488933.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2069..2821
                     /gene="xth"
                     /locus_tag="JXV47_002965"
     CDS             2069..2821
                     /gene="xth"
                     /locus_tag="JXV47_002965"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HAX1488934.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            3685..4218
                     /locus_tag="JXV47_002966"
     CDS             3685..4218
                     /locus_tag="JXV47_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HAX1488935.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
BASE COUNT         1323 a          878 c          795 g         1490 t
ORIGIN      
        1 tttacttatt ttaagttcca ttacttatta attggctaaa cttctgcttg tttctgatat
       61 tgcttgtttt tctccaatga tccgcacttc tgtttctaaa gacacatcaa atttttcttt
      121 gattacttct tggatgtgcg caatcaattc aatataatct gtcgctgtcg catgatcgat
      181 attgacgatg aatccagcat gtttttcaga gacttgtgca ccgccccatt tcaggccttg
      241 caatcctgct tgttggatca gctgacctgt atagtgtcct actgggcgct taaagacact
      301 tccgcatgaa gggtattcta atggctgttt tgattgacgc aattcggtca actcatccat
      361 tcttgctttg attgcttcat aatcccctgt ttgcaaactg aatcgagctt ccaatacgat
      421 agcacgtaat tcttggactt tactgtgacg ataagaaaat accatttcgt cttttgtcaa
      481 agttttcaat gttccatctt caagcaaaag atccacttca gcaaaaacat ctttgatctc
      541 tccgccatac gcacctgcat tcatataaac cgctccaccg acacttcccg ggatgccgca
      601 agcaaattca aatccagtca atgattctgc caaagctgca taagtcgtat caatcagtga
      661 ggcacctgct tccgcaatga ccatcgttcc tttgacatga atctgtttca tttcagtcag
      721 catgatgact acaccgcgaa tcccgccatc ttgaacgatc agattgcttg catttcctaa
      781 taccatccaa ggtatatcat ggattcggca ataatcgatg atttgcttta cttcttcttg
      841 ttttttcggg aatgcaagga catcagctgg tccacctgtt ttcgtaaacg tatagttcat
      901 caatggttca tcaaacaata tagtaatcgt ggctaagctt tcaactattt cttctttatt
      961 cactgaggat tttcctttct tttctcaaac gtcctcatta ttctatcacg cttaatacaa
     1021 tcttgccagt cttgttcaaa gttgatgacg gtagtgatct ttaagcactt cctcacataa
     1081 ttcatgactt cttacaactt ctttttgttt aagcaattct gtttccgatt tacctaaacg
     1141 gatctgagaa aagaaggcct ctaccattgg ctcaaacccg cgtttgacta gcgtgtttgt
     1201 ccagtcgcca aattctttca ctttttttcc atcagcatct tgaatgacaa gctgggtcag
     1261 atcgtttact tcataagtac catttttact tgttacttga tatttttcta tattagcgcc
     1321 acttgctaaa tccatcgtta aaatagccgt ttgattttgt gtttctaatt gtaaaatggc
     1381 atattccaaa aattcctttg tttctcttat ctggtatttt gttctcaaaa tgggttcatc
     1441 taataaatac acagctgtat caataagatg taaaaacaaa tcataaagga cgaactctgt
     1501 cgtttctttt gccgctattc gatttttttg caggtggatc aaccgcttat ctgggatacg
     1561 tttcaattct tctaccatag gagcaaagcg ccggttgaaa ccgatcatca aaattatttg
     1621 gttcttatca gctaattctt gcaattcacg aacttcattt agatggacac tcagtggttt
     1681 gtcaatataa acatggatac cattttctag acattttttg gctaattcat aatgtacttt
     1741 tgttgctgcg tggatcatac atgcttcgat tttttcttct aaaagctcat cgatcgtttc
     1801 atatagatgt tggaacccgt actctttttg aattctttct tttgtttctt tatttcttgt
     1861 tgcaaaataa aaatcaagtg ttccttgttt tttcgcataa gttggtaaat atgctttttc
     1921 tgcgatattc cctacaccga ttacaccaat cttcatctac tttcctcctg gatcatttag
     1981 ttactttcat cttacaccat tttttactaa aatgaggtac aatagtatcg caaaggtaag
     2041 gaaattaatt cgaaggagtg tgcttttatt gaaatttatc tcttggaacg taaacgggct
     2101 tcgtgccatc gtaaataaaa attttttaga agtttttcat gagttagacg ccgatttttt
     2161 ctgtctgcag gaaacgaaac tccaagcagg acaaattgat ttagatcttc caggttatta
     2221 tcaatattgg aattacgcgg aacgaaaagg ctattccggc acagcgattt ttgctaaaaa
     2281 accagcattg aatgccactt acggaatggg tatcgatatc catgatacag aaggccgtct
     2341 gattactttg gaatattccg atttctttct tgtaacctgt tacacgccaa attctcaaag
     2401 cgaattaaaa cgtttagatt accgattaga atgggaagaa gccttttata attatttgga
     2461 aaatctaaaa aaacaaaaac cagtcatcgt gtgtggggat ctaaatgtcg ctcatcaaaa
     2521 gattgatttg aaaaactgga aaacgaatca aaaaaatgct ggattcactc cagaagaaag
     2581 agcggctctt tctcgactgt tggataacgg gtttatcgat acattccgtt atttttatcc
     2641 aacccaggaa ggtgtctact cttggtggaa ctaccgattc aattcaagga aaaacaatgc
     2701 tggttggcgg atcgattact ttttgacgag caaagattta gagccaggac tagctgatgc
     2761 aaagatccat acggacatta tgggcagtga tcattgtcca gtagaattag atttgaaata
     2821 aagaggttgt gaaaaagtcg tttagtttcg agtattaaga aaaattttgt gaaaatggct
     2881 ttccacattt tgcataaatt tggcataata ccgagaaact ggcttttgaa cactgtttat
     2941 cgagagattg tgaaaaagct gtcctgcatc aagtaataag aacagccaaa caaaaatagt
     3001 tcctcatatt tttcgtttgg ttgggcttat taccgcagat acaagctttt gaacaccgtt
     3061 tattaagagg ttgtgaaaaa gctgcactgc atcaagtaat aagaacagcc aaacaaaaat
     3121 agttcctcat atttttcgtt tggttgggct tattaccgca gatgcaagct tttgaacacc
     3181 gtttattaag aggttgtgaa aaagctgcac tgcatcaagt aataagaaca gccaaacaaa
     3241 aatagttcct catatttttc gtttggttgg acttattacc gcagatgcaa gcttttgaac
     3301 accgtttatt gagaagttgt gaaatcagcg tcctgacctg agtattagag aaacaaatgg
     3361 caaaatagtt cctcatattt tgctattttt tgagctaata ccgagggtca gctgattgaa
     3421 caccgtttag tggagaagtt gtgaaaaagt cgcctacttt cgagtcgtaa gaaatttttt
     3481 tgaaaatggt tcctcacaac tttgcataaa tttgacttaa taccgagaag tcatgatccc
     3541 catctaactc caaatcacaa ggaatgagtt caaaaactag cttttctcaa caaatattac
     3601 ataaaaaatt ctatgttttt tgttaaattt atttgctttt ttcaaaagta tgttacagta
     3661 atttcccaag gaggttttac agaaatgaat tttgttgcca tggattttga aactgccaat
     3721 catcagcctt atagtgcttg ttctcttgcg ctagtcatgg taaaaaatag ccagatcgtt
     3781 gatgaattct atacattgat acagcctgag actccttttt tctggcgaaa tgtccaaatt
     3841 cacggaatcc atcaagaaga cgtacgcaat gcgccgaaat tcccagaagt ctggcaaact
     3901 atccaaccat attttcaaaa aaatcgttta gtcgttgcac ataatgctgc ttttgataca
     3961 aaggtcttag cgggatgctt agattattat catcttgaac agcctaatta tctttcttta
     4021 tgtacagtga aaagtagccg tcgcctgttt cctgaatttc caaatcatcg attgaacact
     4081 gtgtgcgaaa atttgaacat ccaattagat catcaccatg atgcattgga agatagtcgt
     4141 gcatgtgcgg aaatcctgct ttatcaagaa aaaaaattcg ggacagatcc attgaaaaaa
     4201 cttgtgacta taaagtaaaa gaatacttat gaaacacaca aagaggtcgt gagcctgccg
     4261 tttcactccg agtcacaagg agcaatttca aaaaatagct tctcatgttt attaaatatt
     4321 gtgactggtg accgaggagc tggcaggaga acaccgttta ttggagaggt tgtgaaaaag
     4381 ctgttctgca tcaagtaata agaacagcca aacaaaaata gcttctcata tttttcattt
     4441 ggttggactt attaccgcag atgcaagctt ttggacaccg tttacc
//
LOCUS       DADGKS010000158         4454 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.164, whole genome shotgun sequence.
ACCESSION   DADGKS010000158 DADGKS010000000
VERSION     DADGKS010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4454
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.164"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..115)
                     /locus_tag="JXV47_002967"
     CDS             complement(<1..115)
                     /locus_tag="JXV47_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAX1488936.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDR"
     gene            246..698
                     /locus_tag="JXV47_002968"
     CDS             246..698
                     /locus_tag="JXV47_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488937.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            712..1401
                     /locus_tag="JXV47_002969"
     CDS             712..1401
                     /locus_tag="JXV47_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488938.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1526..3877
                     /locus_tag="JXV47_002970"
     CDS             1526..3877
                     /locus_tag="JXV47_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HAX1488939.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3957..4352
                     /locus_tag="JXV47_002971"
     CDS             3957..4352
                     /locus_tag="JXV47_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488940.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
BASE COUNT         1565 a          573 c          885 g         1431 t
ORIGIN      
        1 cacgatcata taagatttct tgaacttcac gatagctaag gttataacga agatagtagc
       61 ccacggctac aataatcaca tcctgctgaa attgctttcc tttaaaatga ttcatcgtta
      121 ttcctcctgc tatctttttc tattattcta tcttatttga tagtagattt aaaactttgc
      181 aacagaacca attatcttat cgtagatata tattataaat ttaataagaa agcgaggtga
      241 gaatcgtgaa aaaaacgata ctaagtattt tttcagtatt tacaatatta attgggggct
      301 attttctttt gaatttagat tctgttaatt caaacgctca aataaaagat caaagagtag
      361 ctgaacataa taataaaaaa atgagtttga ccaaaaatat ctattctatg tcagatgaag
      421 aattgtataa agaatttggt gatttatccg gggaacagtt agaagaaagt attccaggaa
      481 ttagtgactc agataaaatt gttgtcttgt ctgctggtgg gcaattaatg ggagatggca
      541 aatccgaatt agttagttat aaacaaaatc acagacagtt tattgatgtt aatactgatt
      601 ccaacgctat ttcgattaag gatctaaaag agcttttaaa tagtaaaaga aatgaattaa
      661 agcagataaa agaaactaat tcagtggaat tagagtaaag gaagattcat tatgaaaaag
      721 atttttggtg tttctgttgg gctacttatg atgttaacat ttggaaatgc agtatatgct
      781 gctgagaaag aagttatttc agatccagag cagtacgcct cacgatactt tgctgatttt
      841 gaagaagaag ataaagtact tgcattgcca gaaggtggtt ttttaaaagg ggaagctaaa
      901 attgtatcta tggataatcc agatataatt caaggttcat ataattcaga aactgatcct
      961 gcttcagttt cagtgacaga agcaaaaaaa attgttgctg aaaaattcaa aaatgatatt
     1021 gaaactactc caattatgcc tcgaggagca tttccacccg atgttggtac tagcggacac
     1081 cttcttgtac tagcaggagg aggaagctat aaatcacagc catttagtgg tgcgggatgg
     1141 cgttttggag gtatgggtgt aaaaccagct gatggtacag gcaacttttt acgttggaaa
     1201 tcctacattg acgatggaag agtaggaaat gtaaatcaag ccaacgcaac taaatctggt
     1261 tctattcaag gaatggcatt gtatgctcgt gaaggattca aatactttgc accaaacggg
     1321 cctggttgga caatgaatat aggtatttat tacacttata atcctgttgc aggtacgtat
     1381 tatgttgttc aaaatattta ataaaacagc acaaagagat ttctttgtgc tgttttatta
     1441 tttttagttg ttgacaaaca ctaaaatata aaatataatc aacacataaa cgaacgtatg
     1501 ttcggcaaga aagcagggga tttttatgga tgagatggtt ttaagtactc agaaatggct
     1561 aaacaagaaa tacagtaatg ttacagggtt tgataaggtt ccagaaaatg ggcgaacagg
     1621 gtggcctaca atctatggac ttattgaagg actacaagta gaacttggta ttactaatct
     1681 agtagctaat tttggaccta ccactgaaaa aatgtacgat aatcaggtta ctcctaaatg
     1741 gggcaaaaat ctacctaaaa atattgtatt tcttattcaa ggtgcctttt ggtgtaaggg
     1801 gattaatcca ggtggcttcg atggggtata tactccatat ttagatactg ctgtaaaaga
     1861 gttgcagact gatgcagggt ttaatggaag cgctgtaact ggagttttgg atgcgaaatg
     1921 ggccaaagcg ttatttgata tgagtgcttt tgttcttgtt cccggcggag atagtaaaat
     1981 tagaaaaatg cagcaatggt taaatgtaaa ttatttagaa tacacgggaa taatgccttg
     2041 tgatggtatt tatcaaagaa attcaaatca agcattaatt tttgcattac aagctgaact
     2101 aggatattct cccagtgaag caacagggtc ttatggtaat gggacaacta gtaaaactta
     2161 tcctgtgtct gaaggtaact cgggaaacta tgtaagaata attcaatatg gattatatgt
     2221 taatggttat tttgaagacg gtacattcga tggtattttc actaaatata tgggtttaga
     2281 agtactggca ttccgaaaat ttatggtatt gcctgaatat actgaaatag cagatgttgt
     2341 tgtaataaaa ggactattgt ctagcgctgg agatattaga agatctgcag atggcgcaga
     2401 tacttctacg caattaacta gatctcaaat ccaaacattg gttgataatg atataaaaat
     2461 agttggtaga tatcttactg gtactgttgg aattggaaaa gatgaacgaa ataagtatct
     2521 aactacagag gaattgaata atattttttc taaaaattta tctgtgtttc ctatctatca
     2581 agatggaggt gcagcattag cttattttac ttatgatcgt ggcttatcag atggtaagaa
     2641 ggctatagat gcagcaaaaa atctaaatat accattaaca acagttattt attttgctgt
     2701 tgatctagac atgttagggg aagaaattct tgcatatgct ggagaatatt ttaagggggt
     2761 atctgctgta atgtcatata gcgggtatca aacgggtgtt tacggaacaa gaaatgtttg
     2821 ttctcaaata atcaataacg ggtatgcttc gtttgcattt gtttcagata tgtcgactgg
     2881 ttatagtggg aatttaggtt ttcctatgcc tagacaatgg tcttttgatc aatttgttga
     2941 atttaccata ggaagtggca acggagctgt tggtatcgat ttaatcgcta catcgggtag
     3001 agatagcgga tttaatgagt tatcaaatga tactaataat gataattaca ttgccaaata
     3061 caatcagaag gttataaatc agatggtacg tgcgtatcaa tatctatcac aagctggtct
     3121 tgataatcct tggaaccctc atttgacatt ttatagatat gtaaattatt ctggtttgtc
     3181 atgggacatc atttcttctc ctgtaacaga gcatgataga aaaatttatg atgaatatag
     3241 gaataaatta actaatagcg agggcctgta taattatttt atagatccta atactggttc
     3301 aataataggt ttgcctcact taattgtgac gttacaatca cagatgtttc tagccgacac
     3361 aatcaatgat agtgtttctg actttgcagg ttggttagga gatttaatga cttgctgggg
     3421 tgaagttaag aaattaggaa tacaaatgga gcaaggtgta tttgcattag taggtacggc
     3481 tgcaggtgga acatttagtc tagaagattt ataccaagat gttgacgcgg taaatgttta
     3541 taccttagca aaaagaaatt ctgattcaac agctttatcg gctttaaaaa cgtactattg
     3601 tgataagggt gctattgata gatttaatca atttgttaag aacagatttg gttcttcaga
     3661 taaaatcgct tcagtaacaa atagtttatt agaaaatgac gaaacagttg atatcttagg
     3721 tgtagggata atttcatttt tcattgataa aatagttaat aattcacttg ggacagattt
     3781 tacttatctt gattttattg gagatgaggg gaaagttgca aatggatttt ctgaaaaaat
     3841 tattcaattt caagaaaata gaagtaaact taattaagaa tcgtttacta tttaaacagt
     3901 gtccttttcc tttttaaata tatacgataa aataagtata tgaattgtaa aaggacatga
     3961 tgattatgga agaaatagaa tggaataatc tgactcaaaa taataaaaat aattctggat
     4021 gtggaattat ctttatgttt gttatagttt tgggaatagt agtactttta ataactgtca
     4081 agatagtaga ttactttgcg aatactcctg aagaacaaat acagagaaaa cttcctgagt
     4141 ttgaaagagt accaccttat gatccaagag ataattcatt tcaagtaaaa aaattaaaag
     4201 agtctccaaa tgaaatgtgg tttgaagtta cagttgaatc aagcgacttc aaagaaaaaa
     4261 agaaagaata caattatatt gtaaaggcaa aagtatcaaa aagatttatt tttaacccta
     4321 aattagaaat atatagtgtt gtaatagaat aatagtgtta aaaaaattgt aaaagttaaa
     4381 gaagtcaaat tctgatgtga aaaataaaat ataccatgga agacataaaa gaaaaactgg
     4441 ataactagtt tatt
//
LOCUS       DADGKS010000159         4439 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.165, whole genome shotgun sequence.
ACCESSION   DADGKS010000159 DADGKS010000000
VERSION     DADGKS010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4439
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.165"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(454..879)
                     /locus_tag="JXV47_002972"
     CDS             complement(454..879)
                     /locus_tag="JXV47_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488941.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            1253..2224
                     /locus_tag="JXV47_002973"
     CDS             1253..2224
                     /locus_tag="JXV47_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAX1488942.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            2256..3653
                     /locus_tag="JXV47_002974"
     CDS             2256..3653
                     /locus_tag="JXV47_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAX1488943.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            3812..4435
                     /locus_tag="JXV47_002975"
     CDS             3812..4435
                     /locus_tag="JXV47_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488944.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
BASE COUNT         1553 a          714 c          904 g         1268 t
ORIGIN      
        1 ctacgtgatg tagaataagc ctttctatcg tttggttatt ttatattcaa atatttgaaa
       61 taaataaatc tttactcttt gatttgtaaa ctgaaatgat ccactgtttg ttttactgat
      121 gaagcttgat caaaggaaga agctgagttt gaagttcata aaaatcagcc atagtgagtt
      181 ttgcttggat ttgtttatct tcttctactt tttacataat tttgaacagg ataagattca
      241 aatgttttaa atgaatcttt gactagtttg tgacagttgt cgcatatgct caagcttcct
      301 tggtcattaa attctgtatg gatatttttg ttgttattac atgtacaata atcaggacta
      361 tcgatcatcc atttcgtctc ctttacaatc atcttgcttc tttactatag cagaaaagaa
      421 ggggagaaac aaaagaagat ccaacagacg gcactataga ctgtagatgt tgccatcctc
      481 atccttcaaa cggtaattac cgatttttgt aaatatgact gttgtttctt ttttattttc
      541 ttttcctgaa ataatatatt cgtcatcttt ggtagtgatc ttgatatctg tcagcactgt
      601 tttttcttca gatgattcag aagaatcagt tccttgtgtc tgatacgtgc gtgtccattc
      661 cattttttta tctgtaaatg tcaactgtcc cgcggataaa tccatatctt tacgtacttt
      721 tagcgtatat acactgttgg tggtatctgc tttttccgct tttaagacag aagaatcggt
      781 tgtttcgtcc gaggattggt cagagccgcc aaacaaatca cagccagtca atgtcaaaag
      841 tcccgcagac aaaataaata gtacgattaa tttcttcaaa atacttcccc catttgatag
      901 gataaagaaa ttataccatt ggaatgtaaa acttcaaacg gatggaagag aaaaacgcac
      961 aaaacaccca caaatagagt aaattttaga ataaaatttt aaaaaggcaa aaaatccgcc
     1021 actttcagaa agcgttttaa aaaagtgttg caatctttta aaaaaatgct atattaaaaa
     1081 tgaaccggtt caaatacttg tttaagtata attaatagtg agaggaagtt gctctactga
     1141 agactttagt tatatggata ttgatgacaa gcaacactat gcaaagaatg cggtcatcat
     1201 aatcgaacaa caagaaagag aaatcaaatg taactggcag gagtgagaat gtatggcatc
     1261 gatccgtgat gtggctaaga tggctggtgt ttcagtggga acagtttccc gttacttgaa
     1321 tggtcagcaa ctgaaggaaa agaacatgaa aaaaatagca gaagcgattt cagcgttgga
     1381 ctataaagaa aacatcattg ctaaagggtt gaagaataat cgaagcttct ctattggact
     1441 tttgataaac gggatttcca gccgttttgg gtcggaagtt gtctcaggga tcgaaagagt
     1501 agctgaagaa aatgggtata gcttattatt aagcgggttt gccgatcagc cagaaaaaat
     1561 tgaacaaaaa attgaatacc tgatgaagca tgtgatcgat gggctgattg tcttcttatc
     1621 cgaagaagag tggtctggat ttgaaatgct cacaaaaatg agtattccag ttatcgcatt
     1681 gaattgtcca gaaggaccag caggtattga tacaatatta gtgaatgatc gagaaagtgt
     1741 agcaaaagtg atcgctcatc atggtgaaca aggacataaa aaaatcggat ttattgctgc
     1801 cactcaaaca gactacgtag caagagaacg tttagcagga gccaaagaag cggtccaaaa
     1861 tgatccatcg atccaattag aggtctttac aggagactat tctagaaaaa gcggctatta
     1921 cggggcaaaa gcattattag aaaaaggggc aactgctatt tttgtcagca attacaatat
     1981 gtcgattggt gccatcgaat gtttcaatca agaaggtgtc agaatcggga aggatattgc
     2041 gttcagtcac tatgattatt tagataaaaa cgatctgagt atccttccga aaatcacgat
     2101 cacgccacca acagataaaa tcggggaacg agcagcagaa cagctgttaa aacgaatcaa
     2161 aaaagaagag gaagaaaatg aaaaagtgat tgtgatggaa aatatcatac atggaatcaa
     2221 ctaaaacgaa ctaaaaaaga aaaagaggtg ctttgatgaa aaaatatcaa tttccagcaa
     2281 atttttggtg gggttctgca gcaagtggcc cacaaacaga aggaaggatt tcaggcgatg
     2341 gaaaaggaga gaacattttt gattattggt acaaaaaaga accgcaaaag ttctttgatc
     2401 aagtaggacc tgaaaaaacc tcgcaagttt atacgaagta tcaagaggat gtacagttga
     2461 tgaaacagac tgggcataat tcatttcgaa catctatcca atggagccgt ttgatacctg
     2521 atgaatctgg aacaatcaac gaagaagccg ttcgtttcta tcatcgttat tttgatgagt
     2581 tgattgaaaa cggtatcgaa ccctttgtga atctgtatca tttcgatatg ccgatgtatc
     2641 tgcaagaaaa aggcggatgg ttgaaccgag aaacggttga agcctatgaa aaatatgcca
     2701 aaagttgttt tgaattgttt ggttcgaaag taaaaaaatg gtttactcat aatgaaccaa
     2761 tcgttccagt cgaagcaggt tatttatatc gatggcatta tccagaagag tcagatatga
     2821 aaaaagcgat ccaagttggc tatcatgaag cgttggcttc agcgttagcc atcaaatctt
     2881 accatgaaat ggagcaaggt ggtgttattg gtatcatctt gaatctgaca ccaagctatc
     2941 caagagacga atcaaaccct gaagatgtta aagcagcgca aatagcagat gcgttcttca
     3001 atcgttcatt ccttgatcca gctgtaaaag gcgagtttcc aagtgaattg attgagatag
     3061 taaaagaact tgatctcatg cctgtgatcc atgcagagga tttgacggtt atcaaagaaa
     3121 atacagtaga tcttttaggt atcaattatt accagccacg ccgggtaaaa gcaaaagaaa
     3181 caccaatcga tactaaaaac ggtccaatgc ctgaggatta tttcgacaat tatgaaatgc
     3241 ctggtcgtaa aatgaatcct tatcgcggat gggagatcta tgaacaagga atctatgata
     3301 ttttgatcaa tgtacgagat cattatggaa atatcgactg ctttatttct gaaaacggta
     3361 tgggtgtaga aaacgaagca cgatttatca aagaagatgg catgatccac gatgattatc
     3421 ggatcgaatt tgtccaatct catctgaaat atgtccatca agccattcaa gaaggtgcca
     3481 attgtttagg ctatcatatg tggacatgta tggataactg gtcgtggacc aatgcatata
     3541 agaatcgata tggctttatt tcagtagact tagcacaaga tggaaaaaga acaatcaaaa
     3601 aatcgggtca ttggttcaaa gacgtatcag ataaaaacgg atttgaggct taagaaagaa
     3661 tagttgagag caaatgcgtg aaattctcca ttcttaccat tttgtgaaaa agaagttcaa
     3721 ttatttacga tctttttcaa cttttttgtc tttctatttc attttttgta tataatagaa
     3781 tagtcaaaat taaataggag tggaggaaag catgaggaaa aaaagaccgt ttcttctctt
     3841 ttggttattc ggttttttct tactgcttat tttatccgca gcattttcag gaaaaatgac
     3901 agcagatctt gctcagaaag aaacagaaaa aatcgtagca agcaaagaat cagtagataa
     3961 tttcaaaaaa gaattctcaa cttattggtg ggcggagtat aaaataactg ccaattacga
     4021 aaaaggcgaa ttggacattt atttgccaaa aggaaaagaa gaaaatcaat ttattaatat
     4081 cgatgacgta cttagtgcga tttctctcag acaatatcaa tttaaagaca agcatttgac
     4141 cgttttgctt ttgactcatg atggcgacaa agtagcccgt ttgaaaaatg gaaaagtgat
     4201 caccgcttat tctgaaaaag tagacaaaaa agtggtcgcc gatcgtttag cggaatggaa
     4261 aaagacaaat gaacaagtca agaaaacaac tgtctcttct caaaaaaacg agtcgacagg
     4321 aacaagtcct tcagattctg gcagtggaca aacgataacg ggaagtgaag aaaatcaagc
     4381 ctcaattatt acgaatgagt catcacaagg acaatatcaa tcctatggac aatgaaaaa
//
LOCUS       DADGKS010000160         4433 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.166, whole genome shotgun sequence.
ACCESSION   DADGKS010000160 DADGKS010000000
VERSION     DADGKS010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4433
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.166"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(543..2048)
                     /locus_tag="JXV47_002976"
     CDS             complement(543..2048)
                     /locus_tag="JXV47_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAX1488945.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="JXV47_002977"
     CDS             complement(2045..2731)
                     /locus_tag="JXV47_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1488946.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="JXV47_002978"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="JXV47_002978"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HAX1488947.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1239 a          919 c          729 g         1546 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat att
//
LOCUS       DADGKS010000161         4416 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.167, whole genome shotgun sequence.
ACCESSION   DADGKS010000161 DADGKS010000000
VERSION     DADGKS010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4416
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.167"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            59..913
                     /locus_tag="JXV47_002979"
     CDS             59..913
                     /locus_tag="JXV47_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAX1488948.1"
                     /translation="MENSIYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1010..3259
                     /locus_tag="JXV47_002980"
     CDS             1010..3259
                     /locus_tag="JXV47_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAX1488949.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3262..>4416
                     /locus_tag="JXV47_002981"
     CDS             3262..>4416
                     /locus_tag="JXV47_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAX1488950.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTR"
BASE COUNT         1556 a          625 c          806 g         1429 t
ORIGIN      
        1 gtaataatat aaacataata aaacaaaaat tatccaaatc taacatagga gggtggatat
       61 ggaaaattct atatatttag taacagaacc taacactcag ctgaaagatt gttactttaa
      121 tttttgtggg tattcaaaaa cagaacctag acatagtttt ggaccagcta ttcgagaaca
      181 atacttaata cacatagtgc tagaaggtga aggctattat tcaattaatg atcaaaaata
      241 ttttctgaag aaaggccaag gatttgttat cccaccagga gtatctactt tttatcaagc
      301 agatgaaaaa aatccgtggt catatgtatg gttgggttta agtggcaatc ttgtagaata
      361 ctatctaaaa gaaattggtg ttggaaagaa tcatcttacc tttaaagtcg aaaatttaaa
      421 ttcatttaaa ggattaattt ttgaaacttt atcgtatgat caggacaatc tagtcagtga
      481 attgtccaga caaaaacaag tttataaatt tttagaactc ctcttaaatt cagctagtta
      541 tctgaacgaa gggataatta ctaaaaagat gaatcctttt gttcgtcaaa caattgaaat
      601 aatacgtgag aatgcgtatc aaaaattatc tgttaaagat attgctgtca gtctatcgat
      661 acacgaaaat tatttatcac gattgtttaa gaatgatatg ggaatatcaa taaaagagta
      721 tattagtgaa atcaaaattt ctattgcaaa cgatctgtta tcatcaactg aatattcaat
      781 ccagcaaatc agtgacaaga taggattctc aacagtacaa tctttttcta aagcctttaa
      841 gaaagcaaat ggtgtttcac cgggagtata tcgaaaacgt agattaggtc taggaatcat
      901 taatggtgaa taaactaaac atttgatttt gataaatatt cgttacttta aacgcttact
      961 atttatgtga gcgtttttta taatgcaata aagaaacgga ggagagctta tgtataagga
     1021 taatgaaatg aatattattt atcgatcaga aaaccaacaa tttcatttgt ttaatcagga
     1081 gataagttac atttttaaga tatcggaaga tggtaaatta ttgcatttat attatggtga
     1141 gaacttacca gataatgact atagtcatct aattgagatg catcatcggc ctatgacaac
     1201 ctatagaaat gaaaacgatt tgctatattc gttagagcac ttaaaacaag aatttcctga
     1261 atatggtaca acagatttta gacatcctgc tatttcatta ctacagaaaa atggctctcg
     1321 cttatcagat tttgtctatc aagggtacga agtggaagaa ggaaaaccta aactagaagg
     1381 tttacctgct acctatgttg ataataatga tgaaagcaaa acattgaaag tttatatttt
     1441 agattcagtt acaaatgttc aagtagaatt attatataca atttatagag attatcctgt
     1501 tattactcgt agcgcgcgag ttatgaataa aggaaaagat attcaaataa tcgagaatat
     1561 tagcagttta tcattggatt tacccgatgc aaattatgaa tggcaacaat tatctggtgc
     1621 ttggggtaga gaaagaacta ttaagtcgcg tactttacaa caaggaattc aatcaatcga
     1681 atctactcga ggtatttcaa gccatcagca taacccattt gttactttaa aaagaaaaaa
     1741 tactgatgaa aatcaaggag aagctattgg tgcagcacta gtttactcag gaaacttctt
     1801 aattcaagca gaagtagata catgggatgt tactagacta caagttggca tcaatccatt
     1861 tggatttaat tggaaactca atccaggaga aatatttaca gcaccagaag cgattctggt
     1921 ttattcaagt aagggtttaa atgccatgag tcaaactttt catcaactat ttagaaaacg
     1981 cttagctcgt ggtaagtggc gagaaaaaga ccgtcctgtc ttaattaata attgggaagc
     2041 aacatatttt gattttgacg aagaaaagtt ggtaaatatt gctaaaaaag catttgatgt
     2101 tggtattgaa ttatttgtat tagatgatgg ctggtttgga gaaagagaaa acgattgtgc
     2161 aggattagga gattggcatg taaatcctaa aagactacct agaggaatcg gcagcctttc
     2221 agaaaaaatt cgtagttttg gtatgaaatt tggtttatgg tttgaacctg aaatggtgaa
     2281 taaggatagt gagttatatc gcacacatcc gaattggatt atttctacac ctaatcgaaa
     2341 acctaatcat ggtaggaacc aatatgtatt aaattttggg ttagatgagg ttgttgaaaa
     2401 tattttcgat caaatgtgta aaatcattga tgaatcaaac ttagattaca ttaagtggga
     2461 tatgaatcgt ccattgactg atgtatttga cagtcacttg tcagcagatc aacaaggaga
     2521 agtattccac agatatgtac taggcgtata tcgcttatat gaaaaactta taacaaaata
     2581 tcctaacata ctatttgagt cttgttcatc aggtggtggg cgctttgatc ctggaatgct
     2641 tcactatgca cctcaagctt gggctagtga tgattcagat gcaattgaaa ggttaaaaat
     2701 tcaatatgga actagtatgc tgtatcctct ttcgtctatt ggtgctcatg tatcaattgt
     2761 tccaaatcat caaacaaacc gtataacacc tataaaaact agaggaaatg tagctttttt
     2821 tggtgcattt ggatatgagc ttgacttaaa tgaattaagt gaaggcgatt tgaggattgt
     2881 aaaagaacaa attgcctttt ataaaaaata tagaaccata attcataatg gtacttttta
     2941 tagactatta tcaccattcg atgatgataa tcaaaccgcg tggatggttg ttagtcatga
     3001 taagaaaacg gctattgttg ctcattataa aacattaaat gaggtaaatg ctccttaccg
     3061 ccgactgaaa ttaaaagggt tagataatga cggactttat aatgtaggac aaaatagttt
     3121 gcgatctgga atggaattga tgagagcagg actagtctgt tcagatgcat ctagtggaca
     3181 aataaatgat cagaatcgac gcccagaaac atttgatttt gattccaaga tttgggttat
     3241 aacacaggag gaaaagtaga gatgaataac caaaaaagct tacttcaaaa aggagcaatc
     3301 ttaagtattt cactaatgtt aacaagctct caagcaatta atggtgttat tccacaaatg
     3361 aaacagtctt tggggatatc acaaagtcaa agtgaacttt taggaactgc accaagtata
     3421 actgttattt tgtttatctt attatctagt tactttgcca aaagaatagg aatgaaaaag
     3481 acaataattt taggtttatt attagctggt ataggaggaa ttattccagt atttacagct
     3541 accttccaaa ccgttcttat tagtcgagta atattaggtg ccggtttagg agtatataat
     3601 tcattggctg tgacatatat cagctcttta tactctggca atactagagc aacgctatta
     3661 ggtattagaa attcaatgga agctttaggt cagacaatcc ttatttttct tgctggagtt
     3721 ttagtgaaca ttaattggac ggcttcgttt ttagtctatg caattgcgtt tcctgtagct
     3781 ctcttattcg cgctaaaagt tcctgaaatt agagatgaaa atagtgacat acctgaaaat
     3841 catgtaaaag aaaagatgaa tccaatggtt tttgccctag ttctatttgc aatcttactc
     3901 gtaatgaata gtattgctat ttctgtacga tttgcatcaa ttgcaactga aattaaaggg
     3961 gtaaacttta atgctagtaa ctatttagct ctaatgccta tcttaggaat actagcagga
     4021 tttatgtttg gaccaataaa taagtggata ggaaaaggaa ccctatactt gggaattata
     4081 ttctttataa tttcaaattt gttaattgct gtgtcaaacg gtaatatgac gttcctgcta
     4141 acgggtttat ttttatcaag tataacagga tcatggtgct tcccatttat ctttagtaac
     4201 ttagataaag tcactacaaa gaatacaatt aattttgcta cttcattgat ttttattggc
     4261 tgtaatattg gtaattttat agctcctatt gctatgcaat tagcacaatt tctaacaaga
     4321 agtacaaatt tgactgctcc attttttgta ttcgcaggaa tatttattgt gatcctattt
     4381 gtaacatttt ttgcgacaaa taaaaaaaat actaga
//
LOCUS       DADGKS010000162         4403 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.168, whole genome shotgun sequence.
ACCESSION   DADGKS010000162 DADGKS010000000
VERSION     DADGKS010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4403
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.168"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            7..624
                     /locus_tag="JXV47_002982"
     CDS             7..624
                     /locus_tag="JXV47_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488951.1"
                     /translation="MGFQVLFGSLILTIVFLKWKTSNKKSMWSLVGIVLIIFTVTAAT
                     EANYSHKIQSYKGRLVMTKKDVTRYTSSRTGGLYDYAPLDALKYKDHLKKHEVKVGDR
                     WENASHKAYNSKIVYTVEDADEQNITLPVFNYWGTVVKVNGKKSTIENDNGLVSIKGT
                     GKRTIVEVSSTYPTTMILSLLISSITFIFLFTRYLIRCCGEMKID"
     gene            1644..2813
                     /locus_tag="JXV47_002983"
     CDS             1644..2813
                     /locus_tag="JXV47_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAX1488952.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
     gene            3286..3840
                     /locus_tag="JXV47_002984"
     CDS             3286..3840
                     /locus_tag="JXV47_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAX1488953.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
     gene            4094..>4403
                     /locus_tag="JXV47_002985"
     CDS             4094..>4403
                     /locus_tag="JXV47_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488954.1"
                     /translation="MINSAYFHIKYLKKYEYEEVVLDYGLNRQSFLIYAINNGNLPSN
                     KKNIIIETYAYLEGGSKKLIKSCNIEYQLSVGEIKCVFEEDLELDLKKIFASIHDYIG
                     L"
BASE COUNT         1680 a          548 c          714 g         1461 t
ORIGIN      
        1 agaaccttgg gttttcaagt gctttttggt tcattaatct taaccatagt gtttttaaag
       61 tggaaaacaa gcaacaaaaa aagtatgtgg agccttgtag gaatagttct tattattttt
      121 actgtgactg cagcaacaga agcaaattat tcgcataaaa ttcagtcgta taaaggtcgt
      181 ttagttatga ccaaaaaaga tgttacacgt tatacatcct caagaactgg aggcctatat
      241 gactatgcac cattagatgc attgaaatat aaagatcatt taaagaaaca tgaagtaaaa
      301 gttggtgatc ggtgggagaa tgcatctcat aaagcatata attccaaaat agtctataca
      361 gtagaagatg ccgatgagca aaatatcaca ttacctgtat tcaattattg gggaacagtt
      421 gtgaaagtaa atgggaaaaa gagcactata gaaaatgaca atggtttagt gtctattaaa
      481 ggtacgggga aaagaactat agttgaggtt tcatctacgt atccaactac gatgattcta
      541 tctttattaa ttagttcaat aacttttata ttcttattta cacgttattt aataagatgc
      601 tgcggtgaaa tgaaaataga ttagatagat attataaata tgttgattct attttcatag
      661 caatggagaa aatacattag caatatataa aagaaggtat caagagtcac agtgaattta
      721 ttccgaaaag tgaaaagagc aaatataaaa tttaatgaaa atatagaact aaataggaaa
      781 acgtagacgt aattttctac gttttccttt tcatatatat taaatattac ggaaaattat
      841 ataaactaat ttagtgtttt gtttgtaatt cctaattttg ctccactttt agataatttt
      901 taggtctatt taactcatca gacattctat gctcattttt ctccaaattt gtttcaactc
      961 tttcgtactt aattttgcgt atttgaaaat tcttctttta gagtactttt attacgatac
     1021 tagtatgata tatatctata gcaaacagtt aaaatcttcc taaaataagc gaatagcatt
     1081 cctaaaacct ataaaatttt tagatgaagc gacaagtgga caattaataa actacttgaa
     1141 catgaaatta tggatcacct ttcaaattta gaaaatggaa ttcttatact tattgcgcaa
     1201 catttattga ttgcaaaatt atgtgacaaa aaaaactagt agaagaaaga ataatggctt
     1261 gataataaag tactacctat taaaggtagt actttattta atttagtata aattaacata
     1321 ctactatatt ttaggtttca tattatataa attaataata tactaccatt tgttggtagt
     1381 ataatttaaa ggtaataagt tattctttta ttactatgtt tgggttttat agcaaagaaa
     1441 gtttaataag agtttggacc tagcaaacaa tattaatgag gtcattaaat cttattatct
     1501 ttagtgatat aacgaaatat ctacacagac aaaatgatag cgtaaaatat tttgtgtaaa
     1561 tagatattta gggtagaaaa aaagaaagtc cattctgtaa aattaaagtt accacaaccg
     1621 aaattttata ggaggacttt ctcatgccca attttactac agaaattatg gaaacactaa
     1681 tcaataaagg tgatttagat gaattatttc gatgtcattt agaattagct gttaattcat
     1741 tattgcaggc tgaattaaca gcttttcttg attatgaaaa atatgatcgt gctgggttca
     1801 attcaggtaa ttcccgtaat gggaattatt cacgttcatt cagaacagag tatggagaat
     1861 taaatttggt aattcctaga gatagaaatg gtaagttttc tcaacaaact ttacctgctt
     1921 ataaaagaac caatgactct ttagaaacca ctattattca gctatttcaa aaaggaatta
     1981 ctatgtctga aatctctgaa ttgattgaaa aaatgtacgg gcatcactat acgccacaaa
     2041 ccatttcaaa tatgactaaa atagtttctg aagatattat tgcctttaaa gaaaggtcct
     2101 tagaatccag atactctgtc atttttatgg atgctactca cattccttta aaaagacaaa
     2161 ctgtttcaaa agaagcagtt tatattgtaa ttggcattcg attagatgga accaaagagg
     2221 ttcttgggtt tagtcttgct ccaactgaat ctgcttatgt ttggaaagag attcttcaag
     2281 acctaaaaga ccgtggttta aaagaggttt tattagtcgt aactgatggt ttaagtggca
     2341 ttaacgatag tattcatagt gtttatccaa atgctcaatt tcaacaatgt tgtgtccata
     2401 tatctagaaa tatcgctcat aaggttcgtg ttagtgatcg acaagaaatc tgtagcgatt
     2461 tcaaattagt ttatcaagca agttcaaaag aagaagcaaa taatcaaata aggtttatga
     2521 tagataaatg gaaaaagcag tatccacgag tggttaaatt gctcatgaat cctgctatat
     2581 taacctttta taatttccct ccgtcaatca gaagaactat ttattcaact aatttgattg
     2641 aaggttttaa caaacaatta aagaaatata ccaaaagaaa agagcaattt cctaatgaag
     2701 aatctctgga gagatttcta gtatctcaat tcaacaacta taatcaaaag tttctatgcc
     2761 gagttcataa aggttttaaa gaaatacatg atacattaga atcaatgttt taacttgatc
     2821 aacagaatgg gcttttccat ttacacaaaa ttattgacgc tcccgacaaa attatgatct
     2881 tgcgtaaagt tataaaatat taataaaaat attttattaa tgaaaagctt ggtagcacgg
     2941 ttattcatat gctaatttat ttcactttat agtaagggga gttcttagta tattgttcaa
     3001 acttaaattt catataattt aattatgtaa attagctatt ctaagaactt ctacggataa
     3061 ctgcccgtct aaaatttaaa taagagctta gaatcttcat ataagtaagg ttaatttttt
     3121 tgtacaaaaa agtcggaata ttctgagtta ctgaaatgat ataaaatcat aaactaaacc
     3181 ccttgatttt cttcactttt aacagagtat atatataagt tcatgattat ggtaaaatat
     3241 atatataatc atgaactcag aatattttta agaagggaaa caatagtgag ctataatgta
     3301 caaccgttaa ggacaaatga agagatacaa gattttcagt tttggctaag aagaacaagt
     3361 aatccagaaa gagatagttt tttatttttg tttggaatca ataatgggtt acgtatgtca
     3421 gatattatag gattaaaagt tggagacata cgaggtaaaa gtaagcctat tattgttgaa
     3481 cataaaacag gtaagcgaaa accgattttt atagataatt tgagagaaga gattttatta
     3541 tatactgaag gtaaagaaga aaatgattgg ttatttccaa gtcggcaaca aggtcgacat
     3601 ataacaaggg atcgtgtcta tcagatatat gcagatatag cagaaaaatt aggaagagat
     3661 gatataggaa cacatacatt aagaaaaact tttgggtatc actactacaa gaaaactaga
     3721 gacattgcta ccttaatgtt tatttttaat catagctcgc aagcaattac aaaaaggtac
     3781 attggtataa ctgaagatga aataggggca tcgttacgtg gttttaaatt gggaggctaa
     3841 ttgagatatt aggatatatt ttttgtgtat aatgaaaact tagaaggtga gattaatgaa
     3901 gataactgaa ttttcggaag tatttaaaac gtttagtaac atttacaata gaataccaga
     3961 gatagaacaa aatgttgtag ttgataatga ttattatata gagaatgatt ttaataaacc
     4021 aagaaaatat gacaacctat acaattttat acacaataga acaacaataa ataacaacag
     4081 taacactcga gttttgatta attcagcata ttttcatatt aaatatttaa agaaatatga
     4141 gtatgaagaa gttgtattag attatgggct aaatagacag tcatttttaa tttatgcaat
     4201 aaataacgga aatttgccaa gcaataaaaa gaacataatt attgaaacat atgcctatct
     4261 ggagggggga tctaaaaaac taattaagtc atgtaatata gagtatcaat tatcagtagg
     4321 agaaattaaa tgtgttttcg aagaagattt agaacttgac ttaaaaaaaa tttttgccag
     4381 cattcatgat tatataggtt tga
//
LOCUS       DADGKS010000163         4387 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.169, whole genome shotgun sequence.
ACCESSION   DADGKS010000163 DADGKS010000000
VERSION     DADGKS010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.169"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..1035
                     /locus_tag="JXV47_002986"
     CDS             <1..1035
                     /locus_tag="JXV47_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAX1488955.1"
                     /translation="DSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSAYQKRLIELG
                     SEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQQIADWSHQL
                     KISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKKNQWLKIQGL
                     LVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIGDAGLSENVQ
                     EQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARFREIPPIPAR
                     NTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELPLINQIKAGM
                     NYQFIRKEGR"
     gene            1038..1934
                     /gene="murQ"
                     /locus_tag="JXV47_002987"
     CDS             1038..1934
                     /gene="murQ"
                     /locus_tag="JXV47_002987"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAX1488956.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            1948..3930
                     /locus_tag="JXV47_002988"
                     /pseudo
     CDS             1948..3930
                     /locus_tag="JXV47_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
     gene            complement(3995..>4387)
                     /gene="nrdI"
                     /locus_tag="JXV47_002989"
     CDS             complement(3995..>4387)
                     /gene="nrdI"
                     /locus_tag="JXV47_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HAX1488957.1"
                     /translation="LAEYAEKMHAEDPVNPEVTLKEIHENSDFTKETEPFFTFVPTYL
                     DGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNKNFNNQYCLTAKQYAQTFG
                     FPFLADYELRGTPSDVTRIYQILAENNK"
BASE COUNT         1425 a          790 c          998 g         1174 t
ORIGIN      
        1 gattctttgt cagaagagaa gaaacagtat atccgccaaa tggcatccaa tggctttgtc
       61 ggtattttca cttccatgca tataccagaa gatgatgttt cggcatatca aaagcgattg
      121 atcgaactag gaagcgaagc gaaaaagaat aaactagaat tgatggtcga tatttcagga
      181 gaggcattgg aacgagcggg tttttcatta gaagatctaa cgcctttgaa agcaattggt
      241 gtaacaggtt taagaatgga ttatcatatt tccaatcagc agattgccga ctggtcacat
      301 caattgaaaa tcagtttgaa tgctagcacg atcacgccta aagatatcga tgaattgaaa
      361 gaagcagaag ctgatttctc acagattgaa gcttggcata attattatcc acgtcccgaa
      421 acagggctgg acaaagaatg gtatcagaaa aaaaatcaat ggctcaaaat tcaaggtctc
      481 cttgtccaag gttttgtacc aggagataca gagttgagag gcccactata tcaaggattg
      541 ccaactttgg aagaacatcg agggatccat cctcttgcag gcgctctaga tctattagca
      601 agtaacacgg atattgttta catcggagat gcaggtctgt cagaaaacgt tcaggagcaa
      661 tttgcttctt tccaaaaaga acagacagtc ttgctccata cggaacctgt agatgaagaa
      721 ttttacgaat atatattagg gaagcatacg aatcggcaag acgatgcaag agatgtcata
      781 cgaagcgtag atgcacgttt tcgagagatt ccgcctatcc cagcaagaaa tacagctacg
      841 cgtatgaaag ggtctattac tttagataac gaaaagtatt tgcgctatat gggtgagatc
      901 caattaacca aatatgattt gccagcggat gaaaaagtga atgtagtagc taaagttatc
      961 aaagaagagc taccattgat caaccaaatc aaagctggta tgaactatca atttataaga
     1021 aaagaaggaa gataaaaatg agcaaaatca atttagagaa cctaacaacg gaacgcagaa
     1081 accaagaaac ttttggatta gatgagatga gtatttctca agccgttcaa ctaatgaaca
     1141 aagaagatca gaaagtggcc gctgcggttg aaaaagaact gacaagtatc gaaccagtga
     1201 ttgctaacac gattgagtcc tttaaaaaag gtggacgtct gatttatatg ggagccggaa
     1261 caagtggaag actaggtgtg ttagatgctg ctgaatgcgt accgacattc ggtgtagaac
     1321 cggaaatggt cataggtcta attgctggtg gagaagaagc aatgactgta gctgtcgaag
     1381 gggccgaaga ttcttatgag ctagggcaag aagatctaat caagctgaat ttgacaaaaa
     1441 atgatatagt tattggtatc gcagctagcg gtcgtacacc atatgtgatc ggtggattag
     1501 attacgcaaa atcgatcggt gctgtcacag gaacgatttc ttgcaataaa caagccgaaa
     1561 tcagtaaaca cgcggatttc ccaatcgaag tcgatgcagg tccagaattt ttgacaggct
     1621 ctactcgatt gaagtcagga acagcacaaa aacttatctt gaatatgatt tctactatca
     1681 gtatgattgg tataggtaaa gtattcaata acttgatggt cgatgtcaaa ccaacaaatg
     1741 aaaaactaat cgaacgctca aaacgaatca tcatgcaagc gacagaagct gattacgaaa
     1801 cagctgaaaa gtactttgaa gaagcagatc aaaatgttaa gctggctatc gtcatgattt
     1861 tgacaaatag tgataaagag gaagctcaag caaaattagc tgaagcaaac ggatttgtaa
     1921 aagggacctt atgaggggga aaagaccatg gcaaaaaacg aactgacttt ggaagaactg
     1981 gcaaaacaaa tttataaagg ggcaggcggc atgggcaatg tagaaagcat tgtccactgc
     2041 atgactcgtg tgcgtatgaa gatcatcaat gatgatcttg taaatgtctc tgaattaaaa
     2101 gcgattccag gagtgcttgg tgtagtagaa gatgaacagc ttcaagtcat catcggacct
     2161 gggaaagtga acaaagtagc acagcaaatg gttgatttgg caggcgtgaa attaggagaa
     2221 aaactttctt ctgtaagtac agctacagca aattcatcag catctggaaa agaccgtgta
     2281 aacgaacggg cacaagaaat gaaagcggca caaaaatcga aacaaaaacc atctaaaatc
     2341 aaatcggtat taaaagacat ttctaatatc tttgtgccaa tgattcctgc atttgtcggt
     2401 actgggatcg tggcagggat tgccgcagtt ttagcaaact tagtcacagc cggaacactt
     2461 gatgcagcaa catggcaaca atatatcgat gtgatgaaca tcttgaaaaa cgggatgttt
     2521 agctacctag ttatctatac aggtatcaat gctgcacaag tttttggtgc aacaccaact
     2581 cttggtggag ttatcggggc cgttgtgatg ctgacaggga tgaatccgga agcaccactg
     2641 aaaaacttat ttactggtga agctcttgca gctggacaag gtgggatcct aggtgtcatc
     2701 ttcgctgttt ggctattgta aatcgttgag aaaaaactgc ataaagtagt acctgatgcg
     2761 gtagatatca tcgttacacc aactctttca ttgattgcca tcggtctgat tgaaattttc
     2821 ttcatcatgc ctttagcagg tttcatttct gatggcatgg tcggtgggat caactgggta
     2881 cttggcgttg gtggagcatt tgccggcttc gttctaggca cattattctt gccgatggtt
     2941 atgttcggac tgcatcaaat tttgactcca atccatgtgc aaatgattga tgaaactggt
     3001 cgtacgctat tgcttccaat tcttgcgatg gctggtgcag gacaagtggg tgcagcattg
     3061 gcattatgga ttcgctgcaa aaaagataaa gaattaacag aaatgatcaa aggagcttta
     3121 ccagtcggga tcctaggaat cggcgaacca ttgatttacg gagtaacatt acctctagga
     3181 cgcccattta ttactgcttg tatcggtgga ggtatcggcg gggcagtgat cggaatgatc
     3241 ggaaatgtcg gggctatcgc tattggacct tcaggagccg ctttgatccc attgatctct
     3301 gacggtaaat ggttaggcta catccttgga ttattggcag cttatgctgg tggcttcgtt
     3361 gctacattct tcttcggtat tcctaaagac cgtttagaaa aagaagaatt agcgactgaa
     3421 acagccacag taaatgaagt gcctgaaaaa gtagtacctc aaacttcagc tgaaagtgtg
     3481 actatcctct catcagttgc tgacggaaca gttgtttctt tagataaagc aagtgatcca
     3541 gtttttgcac aaaagatgat gggtgaaggc tactttgtag aaccagaaaa cggacatatc
     3601 tattctccag ttactggggt agtcagctct gtcttcccaa cgaaacacgc tattgggatc
     3661 acaacgccaa atggtttaga aatcttgctt catatgggaa tcaacacagt tgacttaggc
     3721 ggtacgccat ttgatgtgaa agtaacagaa gggcagcaag tgacacctga tacgcttgta
     3781 gcagaagctg acttagaagc gatcaaagca gcaggcaaag aaacatccat gatcgtcttg
     3841 gtaaccaata tggatcgtgt aaaaaacttt gtcttggaaa aaacaggtaa agcaaaagca
     3901 aaagcacctg tgatggatgt caaagcttaa tatgatagaa acaatagaaa cgaaagaaga
     3961 aactgaaatc tatttttcag cttcttcttt tttattattt attgttttct gctaaaatct
     4021 gataaattcg tgtcacatca gatggtgttc cccgtaattc ataatctgcc aagaaaggaa
     4081 agccaaatgt ttgtgcatat tgtttggctg ttagacaata ctgattattg aagtttttat
     4141 ttccgctacc gactacacca agacaaagtt tatgattgtc ttcatgttcc agatattcac
     4201 gcatcgtttc ggtcaagatt tctgtatcac cgttatctaa accatttccg ccgtctaaat
     4261 aagtaggaac gaaagtaaaa aatggttctg tttctttcgt aaaatcacta ttttcatgga
     4321 tttcttttaa agtaacttca ggattgacag gatcttctgc atgcattttt tcagcatatt
     4381 ctgctag
//
LOCUS       DADGKS010000164         4359 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.170, whole genome shotgun sequence.
ACCESSION   DADGKS010000164 DADGKS010000000
VERSION     DADGKS010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4359
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.170"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(176..1585)
                     /locus_tag="JXV47_002990"
     CDS             complement(176..1585)
                     /locus_tag="JXV47_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HAX1488958.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            complement(1633..3498)
                     /locus_tag="JXV47_002991"
     CDS             complement(1633..3498)
                     /locus_tag="JXV47_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1488959.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(3619..>4359)
                     /locus_tag="JXV47_002992"
     CDS             complement(3619..>4359)
                     /locus_tag="JXV47_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAX1488960.1"
                     /translation="EISPEAVQKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELA
                     EDKLKVEFSPNIYLTLTDHLHYAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLF
                     VKQKTGVELSEDEAGFIAFHFVNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDE
                     ESLNYQRIITHLQFFAQRYLKGEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQ
                     KQEMGIAEQIYLTIHIQRVVSEKKSIQS"
BASE COUNT         1246 a          997 c          743 g         1373 t
ORIGIN      
        1 tttcctgaga aaatatcttc tttaatttta tctgcgactt ccaagtatag tacacgtgtc
       61 cttttcataa cgtcaccctt tgctttacta ttactaaaag aatagcacat aaaaaataaa
      121 aaaagaacac aaatcacatg tgagaagtgt gttctttttc attcagctgc tttaattaca
      181 agtttacgcc atttgaggca attacttctt tataccaatc aaaagatttt ttctttgatc
      241 gattcagtgt cccatttcct tcatcgtcta gatccacata gataaagccg taacgtttac
      301 tcatttctcc tgttgatgca ctgacaagat cgatacatcc ccaaggcgta tagcccatca
      361 aatctacacc gtctgctact gcattagcca tcgcttcgat atgacgacgt aaataatcga
      421 tccgataatc atcaataatc gtgccatcct cttccatatg atcaatggct ccaagaccgt
      481 tttcaacaat gaataatggt ttctggtaac gattgtataa ttcattcaat gcgattctca
      541 gcccttctgg atcgatctgc cagccccatt cacttgcctc aagaaacgga ttttttactc
      601 ctcccagcaa gttcccttct gaagttgctg cttgtggatc agtctcattg attgccgtag
      661 acatataata actaaatccg atgtagtcca ctggatattc ttttagcaac tggaagtctt
      721 tttccgtttg ctctaatttt tccggatcga ctccatattt tttatgggta cgcgctgtgt
      781 atgcagggta ttctccacgt acttggacat ccgtgcagaa aaaattgaat tcttggtttt
      841 ggatcattgt tgctgcctga ttgactggat tggcatcgat gctgtaagtt gttgcataga
      901 taatcatgca gccgatttgg atatccgaac gcaattcgtg gccgattttt acggctttgc
      961 tacttgcaac gaattgatta tgccatgctt ggaaaatatt ttggtactct cctgctccat
     1021 tgctttttac taatccttga cttaaagctg gaaagtgaaa ggccgaattg atttcattga
     1081 aagtcatcca atatttgact ttactgctgt atctctctaa tactgtctga gcaaatcgtt
     1141 catagaagtc gatcagtttt cgatttttcc agccaccgta ttcttttgcc aaatgaagag
     1201 gcatttcgta atgagaaatc gtgatcacag gttcaatatc atattttaag cactcatcaa
     1261 tcagctgatc ataaaattct aatcccgctt cgttaggagt accttcgtct ccatttggaa
     1321 aaattcgtgt ccaggcaatc gaaaaacgat aacatttgaa tcccatttcc gcaaacaagg
     1381 caagatcttc tttgaaacga tcgtaatgat cgattcctcg atgattcggg taaatatatt
     1441 tttcttgatc aatcgtccag tcaaattctt cactgccgat aatcgcaaag cgctgcttac
     1501 ctccaggcat agcatctgca acggatagtc cttttccgtc tcgatcataa gccccttcta
     1561 attgatttgg cagcagttgc tccaccccat aaaaattttt ctgaaaaacg tgattgcatc
     1621 ctgatttcct ccttatttta caattgccag aacatcttcg tttgcaataa tctctttttg
     1681 gtctaattca agtatatcgg caaatgcatc agtattcgta atgacaactg gagtgattac
     1741 gctatagcca gctgctctaa ttgcttcgat gtcaaaacga atcaataaat ctcctgcttt
     1801 gacgagatcc ccttgtttga ctaagatctc aaagccattc ccatttaatt ctactgtatc
     1861 catcccgata tgaatcaaaa tctccgctcc gtcagtcgtt gtgatcccta cagcatgtcc
     1921 agttggaaaa atagtcgtga tctctccgtc tgcaggtgca actagttctc ctacttctgg
     1981 atcaatagcg ataccttttc ccatcacgcc agaagaaaaa acttggtctg gtacttcact
     2041 caatggcagt actttacccg ttaaaggact ttttaaggta tgccgtgctg aagtaatcgg
     2101 ttctcctgca ttcgcatgtt tgttttctaa ttgattgtct tgtgtttgtt cgtcaaatcc
     2161 taaaatcaat gtacctacga atgcaagaac aaaagcaatt cctgtagcta ttactgctac
     2221 tgtcacattt gactctacac catccaccgt attaatgaaa gtcggaatcg tcaataagct
     2281 gaccaaactg ctggagaaag cttttactcc ggaaaatccg ataatagctc caccaatacc
     2341 tccagaaata caagcggcaa tgaatggttt cttcaaaggt aatgtcacac catacacagt
     2401 tggttcagtg attccaaata acgaagtcac tgtagaagaa atccctaatg ctcgaagttt
     2461 cgtatctttt gttcgcaatg ctacagctaa agcagcccca ccttgtgcca agatggctgg
     2521 aagaagcatt ggcatcaata catcaaaccc atattgttcg atattcaaaa acatgatcgg
     2581 tacgaatccc caatgcatgc cgaacatcac gaatacttgc cataaacttc ccatgattag
     2641 acctgctacg attggactaa atccataaat cgagttgaag agaccgccta aagcattacc
     2701 ggcaaccgtc ccgattggtc ctaaagcaag aaatgttaat ggaaccatca ctactaaaac
     2761 gacaagcgga actaaaatca tttgcagaaa ttgcggaatc acttttttta cgaatggctc
     2821 taatttactt tgaacccata cggctagaat gattggtatg acagaagaag tataaccaga
     2881 tggtgaaaga atcactggga tcccaaagaa actgatagct tctcccgcac cagcaactgc
     2941 tgtgatagct ggatacacaa gtgccatagc aattgctact gctaaaaact ggttggcttt
     3001 gaacttttta gctgctgtaa aagcaagcat gacaggtaag aaggtaaaga caccatctgc
     3061 tgcagcaaac aatatttgat aagtaccgct atcagctgtc agccagccca tcaccgttgc
     3121 caatgataag aatcctttca ataccccggc ggctgccatc gcccctagaa aaggtgtaaa
     3181 tatactagag ataatatcga tcagacgatt caaaatattt ttggactctt cttttccatc
     3241 ctccgaaact gcaagacctt cctcatccac gatcgattga taaacatctg ctacattact
     3301 gccaatcact acttgatact gaccgccact ttgtacgact tggatcacgt ccgggtcttc
     3361 ttttaacttt tgcgtatctg ctaaagattc atcttttaat ctgaatcgca accgcgtagc
     3421 acaatgtact aaacttttga cattcttttg tcctcctacc gcttcccata cacgacgacc
     3481 aactgcttga ttatccattg ttttttcctt ctttcttttt tatttaaaaa ataaaaaccc
     3541 agattgaaaa aaacagtcac aaacattcgt gaacctattt tttcaatcca ggttttgcct
     3601 gccatacagt aacaatcctt atgattggat gctttttttc tcacttacta ctctttgaat
     3661 atgaatcgtt aaataaatct gctctgcgat ccccatttcc tgtttttgcg tttgtcgaag
     3721 atactcattg atccgttcga cacaatgaaa cgcttttgga tactttcctt gaactaatgc
     3781 gtagagaaat tcatcttgct cgtcagatcc ttcccctttg agataacgct gggcaaaaaa
     3841 ctgcagatga gtaatgatac gctgataatt caaagattct tcatcgaaca cgatgccgaa
     3901 gaatttactg atgatactca gtatatctct taccattgtg gtagcggtca tcgtcacttg
     3961 catgtcttcg tttccttgtt ggctattcac aaaatgaaag gcaataaaac cggcttcatc
     4021 ctcagaaagt tccacacccg tcttttgttt cacgaacaaa agagcctctt tcgctgcttg
     4081 atattctttc ggataaaatt tttttgtttc aaataataat ggattaggca gttggatatt
     4141 ttcttttgct cgtgtgatcg cataatgaag atgatcggtc aatgtcagat aaatattagg
     4201 cgaaaattca acttttagtt tatcttcagc cagttcgact acttgtttga cccattcgat
     4261 ctcctctgcc ggaatatcag ccatcagctg ctggaattgg tttttagcaa aagaatctct
     4321 taaaacaaat tctttttgga ccgcttctgg cgaaatctc
//
LOCUS       DADGKS010000165         4066 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.171, whole genome shotgun sequence.
ACCESSION   DADGKS010000165 DADGKS010000000
VERSION     DADGKS010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4066
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.171"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            85..1434
                     /locus_tag="JXV47_002993"
     CDS             85..1434
                     /locus_tag="JXV47_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAX1488961.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1562..2152)
                     /locus_tag="JXV47_002994"
     CDS             complement(1562..2152)
                     /locus_tag="JXV47_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAX1488962.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            2299..3651
                     /gene="brnQ"
                     /locus_tag="JXV47_002995"
     CDS             2299..3651
                     /gene="brnQ"
                     /locus_tag="JXV47_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAX1488963.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         1172 a          744 c          789 g         1361 t
ORIGIN      
        1 aaattttgga atcttagttg tgtttttcag aaaactctct taatatggaa gtaattaaac
       61 ttttttagtt aggatgattt aaaaatgaat gaagagcaag aactgcagcg tggactgaaa
      121 aatagacatg tccaactgat ttctattggc ggagcgattg gaacggggtt gtttttaggt
      181 tccggaaagt ctatccagct agctggccct tcgatattgc tcgcctatct tattactgga
      241 tgcatctgtt ttttcattat gcgtgcgtta ggcgaacttc tgttatcaaa caccaataac
      301 cattcttttc tggattttgt tgcagaatat cttggcaaaa aagcggcttt catcactggc
      361 tggacgtatt ggttctgctg ggtatcgatt gcaatggccg atttaacagc catcggaatg
      421 tatgtacgct actgggcgcc tggtgttcct cagtggcttc ctgaactgat tgcattaggt
      481 cttcttcttt gcttgaatat ggtggctgtc tcattgtttg gtgagttaga gttttggttt
      541 gcattgatca aagttgtagc gatcattgcc tttatcctcg taggagctta tatgatcctc
      601 acccactata cgacagatat tggcacagcc agtatcacga atctatggtc tcatggcgga
      661 ttctttccaa ctggtgcaaa aggatttatc ttagctttcc aaatggtaac ctttgctttt
      721 gctgggatag aattagttgg attagtcgct ggagaaacag aaaatcctga aaaagtgttg
      781 ccggaagcta tcaataatat tcctatcagg atcatcttat tttacttagg atctcttttt
      841 gtcattatgg caatctatcc atggaacagc ttgaatccag ataacagtcc atttgtagaa
      901 gtattttcgg aaattgggat cacgattgct gcttccttga tcaatttagt cgtattaagt
      961 gcagcagctt ctgcctgcaa cagtgcaata tatagtacag gacgtatgct tcgttcttta
     1021 gcgcaagaag gcagtgcccc taaaaaattc aaaaagttaa caacacatca tgtgccaggg
     1081 aatgctttga cattttctac tatcgtcatt ttcatttctg ttatcttgaa ttacgtgatg
     1141 cctagtgaag tattcacact agtaagcagt attgccacta cttgtttctt gtttatctgg
     1201 agtatgcttg tctacacgca catgaaatat cgtaaaagta tcctcggcaa aaaagctcat
     1261 tcatttaaaa tgccgttgta cccatttagt aattatctgg tatttcttta catggccttt
     1321 gtgtgtgtcg tcttgttcct aggaaaagat acgagaatcg ctttattact aacacctgtg
     1381 tggttcttgc ttctattact aatctatcat atgaaatatg aacgtaagaa gtaagaaagt
     1441 agttgtgaca gaagtggtca gcttcgagaa ataagaagga atttacgaaa attgcttctt
     1501 aaatttttgt gaaatttcgg cttatttctt ggagataaaa gcttctgtcc cagcctcttt
     1561 tctatttccc cggaaacaac cgctgataat aggcatctgc ttttttatag gaaaaaatcc
     1621 aaataccaga tacaaaaaaa cgtccgaata acccgatcaa cggtacaaaa aagacaccgg
     1681 caatcaagca taagttaatc atcatggaga taagacttcg acggtccttt gacaaaactc
     1741 tcacgacatg ggaatctggt ttatttgctt tcatgatttg cctcatcaag ataccaaaag
     1801 aaaaactcca catcgtgtat actaagacat aagccatctc aggccaaaaa gcttcagggt
     1861 tacgcccgac ccaactagta acagaaggac ataaagtcag ccaaaagagc aaaaagatat
     1921 tcgaccagac cactcggtaa ttaattcgtt ctgccatctg aaatatacga tgatggttca
     1981 cccagatcac cgcaacaaat ataaagctga tggtataagc taataatgta tttcggatga
     2041 cccataaaga atgaaagcta gatgtattag ggatcttgat ctctaataca agaactctca
     2101 aaacaatggc taccactcca tcagtaaatg cttctaatct cgactttgtc acgatgattc
     2161 ctcctcagat gattcagcgc ttttatttta tcacttacgt tattaaataa ccatcgtttt
     2221 atatagggaa ttttctgaaa attgttgcat atttttcgaa attttgttac ttttaaaaaa
     2281 accgtaaagg agttatgtat gacaaaaaaa ttatcattta aagactatct ttttataggc
     2341 tccatgcttt tcggtctatt ttttggtgct ggaaatctta tctttcccgt tcatttgggt
     2401 caagaagcag gcgctgctac cttttgggcg aatctaggtt tcttggttac cggtatcggt
     2461 cttcccttct taggggtgat tgccattggt gtatcgaaaa gctcaggtgt atatgaatta
     2521 gcaaaacgga taaatcaaac atatgcgatg gtttttacca tcttgcttta cttagttatc
     2581 ggaccgtttt ttgctttacc tcgccttgca accacatctt tcgagattgg tttagcacca
     2641 tttatcgatc ctagcagaca gacgctatat ctagcaattt tcagtattgt attttttgtg
     2701 ctggcttggt ggttttcaag aaaaccgaca aagatattag attatgttgg aaagttcctg
     2761 aatcctgcat ttttggtttt attaggtgct ttgcttctcc ttgctttttt gaatccacta
     2821 ggttctgtaa atcaagcgcc tattcagcca aattatcaag agcatgcttt tttcacaggg
     2881 tttactcaag gatataacac attagatgcg cttgctgctt tagcatttgg gatcatcatt
     2941 gtcacaacaa tccaaaacat gggtgtaaca aaacctgctg aaatcgctaa agacacgatc
     3001 aaatctggtg cgatcagcat tatattgatg ggaatcattt atactttgct cgcttattta
     3061 ggtgctatga gcttaggtag ctttgctcta agtgaaaatg gcgggatcac gctggctcag
     3121 attgctgatc attatttagg tacttatggc agtatcttat tagcatttat cgttatatta
     3181 gcttgcttga agaccggtat tggtttgatt acagcttttg cagaaacatt cacagatttg
     3241 tttccgcaaa gaaattacgc attctttgtt gcacttgcta gtatccttcc ttgtttagcg
     3301 gcaaacgtag gcttgacgaa tatcattcaa ttttcgttgc ctgttttgat gttcatctat
     3361 ccattagcaa tgacactgat tttactagtg ttagttggtc ctttgtttaa gcagcgtacg
     3421 gctgtttatc gaatgactac ttattttaca ttgattgctt cgatttttga tgggttgaac
     3481 gcttgcccag aaactatcaa acaaacacct attgttcaaa atcttttata tgttgcggaa
     3541 agctacttgc cgtttttcaa attggggatg gggtggatcg taccagcagt tatcggtttt
     3601 gttatcggac tgatttggag tttcgctaag aaagaagaag tagcagattg ataaaagagg
     3661 ttgtgaaaga gacgttcagc cttgagcaat aaaaagtaat tttgaaaaat ggcttctcac
     3721 atttttgcat aaatttgact taataccgag aaactgactt ttgaacaccg tttattgaga
     3781 ggtcgtgaaa aagccgctta gtttcaagta ttaagaaata ttttgtgaaa atggcttctc
     3841 acatttttgc ataaatttga cttaataccg agaaactggc ttttgaacac cgtttattga
     3901 gcgtctataa actgacctga gtattagaga aacaaaacgg caaagtagct ccatatactt
     3961 tgccgttttg ttttgaacta ataccgaaga gaagctgatc aaacaacatt tcttttataa
     4021 tatagatttt agacatatat atgatataaa aatagttttc gcaaaa
//
LOCUS       DADGKS010000166         4052 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.172, whole genome shotgun sequence.
ACCESSION   DADGKS010000166 DADGKS010000000
VERSION     DADGKS010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4052
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.172"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..1646
                     /locus_tag="JXV47_002996"
     CDS             <1..1646
                     /locus_tag="JXV47_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAX1488964.1"
                     /translation="GEKVEVGGTVDLTDNVTNLPTLPEGTTVTDVTPGGTIDTNTPGN
                     YEGVIEVTYPDGTKDTVKVPVEVTDNRSDADKYEPTVEGEKVEVGGTVDLTDNVTNLP
                     ALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSDADKYE
                     PTVEGEKVEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYP
                     DGTKDTVKVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYAW
                     KEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSDADKYNPEGQKVTTDLNKE
                     PDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVTYPDGSKEEVEVTISVVDK
                     KAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHGTADKNGNFTVKVPKLEAG
                     TKVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTDNQGSNSNQDKNRGKSQSS
                     KVFPKTGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1780..3123
                     /locus_tag="JXV47_002997"
     CDS             1780..3123
                     /locus_tag="JXV47_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAX1488965.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            3235..>4052
                     /locus_tag="JXV47_002998"
     CDS             3235..>4052
                     /locus_tag="JXV47_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAX1488966.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRV"
BASE COUNT         1597 a          599 c          771 g         1085 t
ORIGIN      
        1 aaggcgaaaa agtagaagtt ggaggcacag tagatctaac agataatgta accaacctac
       61 caacattacc agaaggaaca acagtaacag atgtcactcc tggtggtacg attgatacca
      121 acacaccagg taattacgaa ggggttatcg aagtaacgta tccagatggt acgaaagata
      181 cagtgaaagt tccagtagaa gtgacagaca atcgttccga tgccgataaa tatgaaccaa
      241 cagtagaagg cgaaaaagta gaagttgggg gcacagtaga tctaacagat aatgttacta
      301 acttgccagc gttaccagaa ggaacaacag taacagatgt tactcccggc ggtacaattg
      361 ataccaacac accaggtaat tacgaaggtg tcattgaagt aacgtatcca gacggtacga
      421 aagatacggt gaaagttcca gtagaagtga cagacaatcg ttctgacgcc gataaatatg
      481 aaccaacagt agaaggcgaa aaagtagaaa ttggaggcac agtagattta acagataatg
      541 ttactaactt gccagcgtta ccagaaggaa caacagtaac agatgttact cccggcggta
      601 caattgatac caacacacca ggcaattatg aaggtgtcat tgaagtaacg tatccagacg
      661 gtacgaaaga tacggtgaaa gttccagtag aagtgacaga caatcgttct aatgcagata
      721 aatacaatcc tgaaggacaa aaagtgacta cagacttaaa taaagagcca gatgcatctg
      781 agggaattaa gaacaaagaa gatttaccaa aaggaactac ttatgcttgg aaagagaaag
      841 tagatgttag cacagctgga aataaaaaag gtactattgt agtgacatat ccagatggat
      901 catctgatga agttgaagta gacgttacag tgacagatac tcgttccgat gcagataaat
      961 ataatcctga aggacaaaaa gtgactacag acttaaataa agagccagat gcatctgagg
     1021 gaattaagaa caaagaagat ctaccaaaag gaactactta tacttggaaa gaaaaagtag
     1081 atgttagtac agctggaaac aaaaaaggta ctgtagtagt aacatatcca gatggatcta
     1141 aagaagaagt agaagttact atttctgtag tagataaaaa agcaccgaat aaacctcaag
     1201 ttgatcctat tacagagggt gaccaaattg ttactggtaa aactgaacca aatgcagagg
     1261 tgacagttac attaccagac ggaagtcaac accatgggac agctgataaa aatggtaatt
     1321 ttacagttaa agttcctaaa ttagaggcag ggacaaaagt gatagtaact gcaactgatg
     1381 aatctggtaa tactagtgaa cctactaatg tagttgtttc ttccaacaaa aaagacagtg
     1441 gaaaaaacgg tagtaaaggt agtaagactg acaatcaagg tagcaacagc aatcaagaca
     1501 aaaatagagg caaaagccag tcctcaaaag tttttcctaa gacgggagag agtgacagta
     1561 atatctttac tattagcggt ggtttaatac tgttaggaac gttaggatta ttagggtata
     1621 aaaatcgaaa aaaagagaat gaatagaaaa tcaatttctt aagtcttctc tgagaagagg
     1681 aagaatcttt ttcttcctct ttttgctttt ttatgatggg aaataagtgt tagttaaaga
     1741 tgaatatact ttttatagaa aggaaaagaa tgtaattaag tggaaaaaat agtaattatt
     1801 ggttcaaacc attcagggct agccgcagct cgatttctaa acttaagcga ttcaaattat
     1861 gaagttattc taatcgataa aaaatcagaa attagttact tggaatgtgg gacatcgtta
     1921 tttataaaag gagaagtaag taatttagaa gatctttttt atcaaaatag aatgacacta
     1981 aattctgaga taaaaaagtt atttctagag acagaagttg acaaaattga tattcaaaat
     2041 aaaaagatta gttgtgtaaa aaaagatggt acaagattct ctcaagaata tgacaaagtt
     2101 atattagcta caggttcaaa gcaaattatg ctagatatac cggggaataa tttagctaat
     2161 attttttcga taaagaattt tccaaatgca aaagagattt ttaaagcttt ggatgatagt
     2221 actattaaaa aagtaggaat tattggagca ggatatattg gagttgaaat tgctgaagcc
     2281 ataagaaaaa gagggaaaga agtatatctt ttcgatgttg cagatagagt gttgtcgact
     2341 tattacgacc gtagtttttc agataaagtt gaagaaatac tatcaaaaaa tggaatacat
     2401 ctttgtctat cagaaagtcc taaaaaatat ttaggaagaa aaaagattga aaaaatagtc
     2461 actacaagtg gtacccaata ctctatggat atggtcgtac aagctatagg atttctatct
     2521 aatagtccaa ttggggaaaa ggaactcttg agagatgtta gtggagcata tctaactaat
     2581 gaataccagc aaacaaatat aaaagatata tatgctattg gggattgtgc tacaactttt
     2641 tttacgtcca ttaatagaag tagtgttgat ttttctattt ctaatgctct aagaacagct
     2701 tatattgcaa ctcaacatat taacaatcaa gattttacac cttctggttc ccaatttaca
     2761 aatggctttt ctatatttaa ttacaatttt tacgcagcag gtttgaattt aaaaacagca
     2821 cgattattaa gtgagtctat agattatata gaaatagaag atttcattag acctgctttt
     2881 ttgagaaaaa atagtcgtgt aaaattaaga attagctttg aaaaaaatac aaagagaata
     2941 gtaggtgtac aactttgtag tcaagaagat ttatctggac tattatcaat gttttctctt
     3001 gctatagaag aacaaattac attagacaaa ttgaaaatgt tagattattt atttcatcct
     3061 agttttagcc aaccctataa ttttatttta aaggcagtaa caggattaaa cattgaaaca
     3121 taatcgttac taaatgaaat caagaaatat actgtattac tcaattcatt gaaaatattt
     3181 atcataattt ttaatagaaa acactattaa agagaaaaaa gagaggtaaa tcaaatgaaa
     3241 aaatctttaa aacttgcatc agcagttata ttaatgtccc aactccttat agcaacacct
     3301 ttccatgtgt tggcaagcga aaattcaaca tacaaaattg caaaagaaag aaccgagacg
     3361 actgaaatga gtaattccga tgtaacagca gagagtagtg aacttttgac aacttcatca
     3421 agtgaaagta gtacgacttc aaatgccgag tcttcaacaa cttcatcaag tgaaagtagt
     3481 acgacttcaa atgccgagtc ttcaacaact tcatcaagtg aaagtagtac gacttcaaat
     3541 gccgagtctt caacaacttc gtcaagtgaa agtagtacga tttcaagtac cgaatcttca
     3601 acaacttcaa gtagtacaag tgaaataact tcttcgaaag tgacaaaacc aaaccatata
     3661 gaatcttcaa aaaaggaagc gccaaaaacg gaaggacaaa caaaaacttt ttcgacacca
     3721 cagcaaatag aatcaacaga atctttccaa tcacaaccaa tactatctgg taatgaagaa
     3781 attcattttg acaaaaatga atctgtagaa aattttatta tgaaaattgg tgagtctgcg
     3841 agaaaaattg gtcagaaata tgatttatat gcttctgtta tgattgcaca agcgatctta
     3901 gaatctgcca gtggtcaaag ccagttagct caggcaccga attacaattt atttgggata
     3961 aaaggaactt ataatggaaa ctttgtcatt atggtaacaa acgaagattt gggtaatgga
     4021 acgctttata cgacccaatc aaaatttaga gt
//
LOCUS       DADGKS010000167         3977 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.173, whole genome shotgun sequence.
ACCESSION   DADGKS010000167 DADGKS010000000
VERSION     DADGKS010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3977
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.173"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            388..1194
                     /locus_tag="JXV47_002999"
     CDS             388..1194
                     /locus_tag="JXV47_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1488967.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            1206..2426
                     /locus_tag="JXV47_003000"
     CDS             1206..2426
                     /locus_tag="JXV47_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1488968.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            2416..>3977
                     /locus_tag="JXV47_003001"
     CDS             2416..>3977
                     /locus_tag="JXV47_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAX1488969.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNG"
BASE COUNT         1322 a          644 c          835 g         1176 t
ORIGIN      
        1 atgggttccg attatttata tcctgttggc tatggccgtt catcgatatg atgaaccaga
       61 agttgcggag gaattctatg ttatggaaga ggcatatgac gatatgactt atgatgatac
      121 atcttatgag gaacaaccag atagcgctca ttcttccagg atccaacgct atcattgata
      181 ggcacaaaat acgagagagg ctgtgacaac cgtcgcagcc ttttttggtt tattgcaatt
      241 gtctagcatc ttctgtaaaa tagaaacgtt agagaaaatc ttgtatcata gaaaattaag
      301 aaagaaataa gaacgcagct cggtaccaaa aatatggtaa aatggcactt gactgtaatt
      361 cactgaaaat cgcttggagg aacacaaatg tttaaagatt tgtatttatt tatgaaggac
      421 atttatcaga acagaaaatt attgctacag ttttcgatca atgacttcaa atcaagatat
      481 gcaggatcgt ttttaggaat cttatgggcg tttatcaatc cgctatttac tgtattgatt
      541 tattggctgg tatttggtgt tggactgaaa gcacaaatga tcgatgcaaa atacccattt
      601 atcgtatatt tagttaccgg gatgattccc tggttcttct tctcagatgc atttgcatca
      661 actacggttg tttttcggga atatacttat ttagtaaaga aagtcgtatt caatattcgt
      721 atcttgccca cgacgaaaat cctatccaat ctgtacaccc acttattctt cattctgatt
      781 ggcatagctg tcgcgcttat aaatggtata tatccttcag caatgtcttt acagctgatt
      841 tattatttat tttgcatgtg tgctttcttg acaggattga cttggctgac ggcatcgatc
      901 caaccatttt tacctgatat catgcaatta attacgatcg tgctgcagtt gatcatgtgg
      961 acattaccga tattatggag ccctaatcag tttgattcag gtcttgtaag catattgaaa
     1021 ttaaatccgc tgtactatgt tgttcaaggt tatcgtgagt catttttaag tgaagcttgg
     1081 ttctgggagc atggaacata tactttgtat ttctgggttt tcacgttagt aatgttcgta
     1141 atcggctctg cagtgttccg tagattgaaa ccacattttt cagatgtgct gtaaggagaa
     1201 tagctatgac agaatatgca attagactaa aagatatcac aaaatcttat aatatgtacg
     1261 caaaaccttc ggatcgattt cgtgaagccc tcaatccttt taagaaatcc tatcatgatg
     1321 tattttatgc gttgaaaaac gtgaatgtag aaataaaaaa aggtgagatg atcggtttcg
     1381 tgggagaaaa cggatcggga aaatctacaa tgttgaaaat cattacggga gtactgacac
     1441 caacatccgg cacgatggaa atcgaaggaa aaatctcagc tttgctagaa ctaggatcag
     1501 gattcaatcc tgagtattct ggctatgaaa atatctattt aaatggaatg gttctaggat
     1561 tttcaagaga agaagtcgat gaaatggtcg atgatatcat tgaatttgct gacatcggag
     1621 accatattta tcaacctgta aaaacttatt caagcgggat gttcgttcgt ctagcttttg
     1681 ctgtagcaat caatgtgaat cccgatattt tgattgtgga tgaagcattg gcagtaggcg
     1741 atcttgaatt tcaactaaaa tgtatggaaa aatttacaga aatcaagaac tcgggaaaga
     1801 cgattttatt cgtttctcat gatatcagtt cgattcgtcg tttttgtgat cgttcctatt
     1861 ggttgaaaaa cggagaagtc gtcgaatatg gcgatacgat ggaagtaacg acgaattatg
     1921 aaaacttttt aaagaaaaaa tcagttaaaa cagtggatcg gaataaaaac caagtagaac
     1981 ggttcgccgc tccagatatc gtcgacgtga cgaaagcgga attgttggat aaagacaaaa
     2041 atccggtgga tatgctggaa caaggagaaa aactatacgt taaagtaact tatgaagtaa
     2101 aagatgatac aatcaaaaat ccggttttag gaattgcgct acgaacagtc gacaattttt
     2161 atgtatgcgg acttaatact ctactagatg gtatcaagat tccttggaaa aaaggagaga
     2221 atatctttta tctggagtat gaaaagttag gtttgttagc tggtgaatat tattttgacg
     2281 ttgcggtctt tgaagaaaat gcaacggttc ctttggtata taagacaaag tacatgaact
     2341 tgtttgtcag cggttcttat atcggagaag gcatcgtggt cttagaccat aaatgggaag
     2401 aagggactca tagcaatgaa atatgatttt gaaatggacc tagatgaaca aagcagtgtg
     2461 ggaaaaattg ccgcacagat caaaccagga agtaaagttt tagagtttgg tcccggaaac
     2521 ggccgattaa cgaaacattt aatcggagca aaacaatgtg aagtgagcat tgttgagtta
     2581 gataaggaat tgttcgattt tgtcagcgaa tttgctcaag atggatttta tggtgatatc
     2641 gaaagttttg agtgggcaaa ctattatgct ggacagacat ttgattacgt cttgtttgcg
     2701 gatgttttag aacatttggt agatcctgga aaaacattga agaaagtcag agaatttttg
     2761 aatgaagaag gagagatcct gattacattc cctaacttgg cgcataattc tgtcatgatc
     2821 gatttgttca ataaccaatt gccgtgggct tcttatggtc tcctagatga aacccataat
     2881 tctttttata ctcatgatgg cttccaaaaa gtttttgaaa aagcgggatt attcattaat
     2941 attgaagatt atttgtactt agctgtaggt gatacagaat taaaatcaac ttatgaagaa
     3001 ttgccggaag ctgtacgcta tgatttcaaa atgcgaccat ttggtgaagt ctaccaatac
     3061 tttttctcat tgatgaaaca tccagtagca caaagttcca ttgcagagcc acaaaattct
     3121 aattatgtaa aagtgttaga agtaacccag caaacgaaac aagatgaaac aatccaacaa
     3181 ataccattca ataatttcac aggggaaaat gagacactaa gtttccccgt atcagaaaca
     3241 acagaaagaa tggtgtttcg cttcgcgcaa caacctagct ttatcgaatt cagcgcagaa
     3301 gctgccggag aaaaactaac atttatcgat tcgaatgctg tagtcaaaac agtaaatgat
     3361 tgttatttgt ttgatgggaa agaattacca gagttcgttc taacggatat ttctgggaaa
     3421 gaagtgacta tccattgtca ctatcgcttt atcggggaat tgacaccaac aatgaaagaa
     3481 ttgttggaaa cgattcgtcc catggctgaa gtcacaaagc agctttctga gaaaaatgac
     3541 gaattagaaa gagaaaatca tcatcttctt gaggaaaata caagactaga ccatacgtta
     3601 aaaacaacca caaatcgcta ttgcacattg ttggaaagtg atgaatggac aataaaacat
     3661 agactaggac gacgtaagaa agaaacttcg aaaaaaatcc aagaaaaaga actttctata
     3721 tgtattgacg agaaaatctg ggatgcagaa acaaaaatat taaaaatcat cggatgggga
     3781 atcgctaatt cggatcgcca gcccttgtcc tataagttat cagctgacca atcgccattt
     3841 ttcgaagcaa ttcctgtttc acgagaagaa gtcaatcaag cagaacagct cgcaaaagga
     3901 acagaagcgg gatttgagtt acgaatcctt tgcgagcaag aacgttcatt cttagtggaa
     3961 gcagtagctc aaaatgg
//
LOCUS       DADGKS010000168         3930 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.174, whole genome shotgun sequence.
ACCESSION   DADGKS010000168 DADGKS010000000
VERSION     DADGKS010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3930
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.174"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..155
                     /locus_tag="JXV47_003002"
     CDS             <1..155
                     /locus_tag="JXV47_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HAX1488970.1"
                     /translation="KDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPVDAI
                     SYGVRK"
     gene            174..1451
                     /locus_tag="JXV47_003003"
     CDS             174..1451
                     /locus_tag="JXV47_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1488971.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1461..2117
                     /locus_tag="JXV47_003004"
     CDS             1461..2117
                     /locus_tag="JXV47_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1488972.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2117..3493
                     /locus_tag="JXV47_003005"
     CDS             2117..3493
                     /locus_tag="JXV47_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1488973.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            3623..>3930
                     /locus_tag="JXV47_003006"
     CDS             3623..>3930
                     /locus_tag="JXV47_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAX1488974.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     "
BASE COUNT         1585 a          418 c          687 g         1240 t
ORIGIN      
        1 ataaggataa gtgtattaat tgtggaaaat gtaaaaaagt ttgccaaatg aataaagatt
       61 cagttgagaa ttgcaatcat ctggagtgta tcagatgtgg acgatgtaaa aatgcttgtc
      121 cagtggatgc aattagttat ggagtaagaa aatagagagg agtagttagg aaagtgataa
      181 aaaatgctat agcatatatt acaagaaaga aaaatagaac tttaataatt tttatcatat
      241 taactatagt tctttcttgc ttgtattctt gtttaacaat aatgaaatca agcaatgaaa
      301 tagaaaaggc tttatatgaa agttctaatt cttcaatatc aataacaaaa aaagatggta
      361 aatattttaa tgttaatcaa tttaaagata ttgaaaaatt aaaagaaatt gaagaaaaaa
      421 taattcaata tgatggatta gcaaaactaa aagatgctaa agtagttagc ggagaacaaa
      481 gaataaatag agaagattta tctgacgaat ttaagaatgt tgtttcactc gaagctacaa
      541 ataatactaa aagaaatatt ttatttagta gtggagtatt tacaattaaa gaaggtaaaa
      601 atatagaaga aaatgataag aattcaatta ttgttcatga agaatttgct aaacaaaaca
      661 atctaaaatt aggtgatgaa gttgatcttg aattactaga tattgaaaaa agtggaaaaa
      721 taaaaagtca taaatttaaa attataggga tcttttctgg taaaaaacag gaaacatata
      781 caggattatc ttctgatttt agtgaaaata tggtgtttgt agattattca acaagccaag
      841 agatattaaa taattcagaa aataatgaaa ttgcaaataa aattttaatg tattctggta
      901 gtgcagaatc tacagactta gccttaaaca aattgaaaga gcttaaaatt gatgagtcaa
      961 agtattttgt tgaaaaagat tctaatgcgt ttgaagagtc tttagagtca gtgagtggaa
     1021 taaaatatat aataaaagta atgacttatt ctattatgtt aggtgggatg gttgttcttt
     1081 cattaatctt gattctatgg ttaagggaaa gaatttatga aataggtata ttcttatcta
     1141 ttggaacatc taagatacaa attataatgc aatttatatt cgagttaata ttcatatcga
     1201 taccaagtat aatatcttcc ttatttttag gaaatgtatt actaaaagta attgtagatg
     1261 gattcattaa ctcagaggat tcaatgattt ccggtggaag tttaataaat aatagtagtt
     1321 ttatgtcaaa tataacaaca cttggacaaa gttatttaat attaataagt attattgttt
     1381 tatcagttgt atttgcttct tcattaatgt taatcaagaa gcctaaagaa atcttatcaa
     1441 aaataagtta ggagaaaata atggatatat tagaaataaa gaatgtagca tatagttatg
     1501 caaattctaa agaaaaagtt ttgtcaggag taaatcaaaa atttgaactt gggaagtttt
     1561 atgcgatagt aggaaagtca ggaacaggaa aatctacact tctttcctta cttgctggac
     1621 ttgataaacc tcaaacagga aaaatattgt ttaagaatga agatatacaa aataaaggat
     1681 atagtaatca tagaaaaaat aatatatctt tagtatttca aaactataat ttaatagatt
     1741 atttatcacc aattgaaaat attagattag taaataaatc agcagatgaa agtatcttgt
     1801 ttgaactagg tttagataaa aaacaaataa aaagaaatgt tatgaaatta tctggtggac
     1861 agcaacaaag agtagctatt gctagagcat tggtatcaga tgctccaata atactagctg
     1921 atgagcctac tggtaatcta gacagtgtta ctgctggaga aataattaat atattaaaga
     1981 cattagctaa agatagaaat aaatgtgtaa tagttgtaac acatagtaag gaagtagcag
     2041 attctgcgga tatcatttta gaactaagtg gtaaaaagtt gaaaaaagta aataaaatga
     2101 atttggaggt tgaataatga taaaaaatgc atttgcttat gtaactagaa aaagtttaaa
     2161 atcattaatt atcatattag ttattttatc tatgtcaact ttaagtctca ttagtttatc
     2221 tattaaagat gctacggaca gagcttcaaa agaaacattt gctaatataa caaatagttt
     2281 ttctatggag ataaatagac aagtaaatcc aggaacacct agaggtgggg gaaatgtaaa
     2341 aggtgaagat attaaaaaga tatctcaaac agatagtata gactcctatg taaaaagaat
     2401 aaacagtgtt gcagatttag ttgattatga tattattgaa actcaagaga ctcttgcgaa
     2461 tcaatcacct gaaagagcaa agaattttaa aagaacagtt atgttaactg gggttaacga
     2521 ctcaacaaaa gaaacaaaat ttgtatcaga agcatataaa ttagtagaag gaaagcattt
     2581 agaaaatgaa gataaaaata aaatcttaat gcataaagat ttagctgaaa aaaataacct
     2641 taaagttgga gataagataa aaataaaatc taatttattt gatgctgata atgagaaagg
     2701 tgcagatgaa acagtagaag tagaaattaa aggtctattc gatgggcata atagcggtgt
     2761 agtaagtgca gcacaagaac tatacgaaaa tacattaatc actgatattc atacagctgc
     2821 taaagtttat ggtaataccg aagatacagc tgtataccaa gatgcaacat tctttgtaaa
     2881 aggtgataag aatcttgata gtgtaataaa agatcttggg aaattagata taaattggag
     2941 agaatataat ttgattaaaa gttcatcaaa ttaccctgca ttacaacaat ctatatcagg
     3001 tatttactca atttcaaata aattattttt tggctcatta atatttgcag gagttgtagt
     3061 ttcattatta ttattcttat ggatgaatgc tagaaagaaa gaaatagcag tattactatc
     3121 attaggtata tcaaaattag aaatttttgg tcaattccta attgagatgg tatttatatc
     3181 aatccccgca ttcgttggtt cctatttctt agctcaatat acagctgaca agcttgggaa
     3241 taatatattg aataaggtta ctggtgatat agctaaacaa atagctaaac aatctgcatc
     3301 tagccaatta ggtggtgggg cagaagctga aggatttaac aagacattat caagtttaga
     3361 tatcaatgta ttacctaaat tcatgattta tgtagttata tttatgagtt tagtacttct
     3421 tgtatcattg attatttctt cattcaatat attaagaagg aatccaaaag aattattaat
     3481 tgacaataat taaaattttc ggtgcttttt agcaccaaaa atgagagtgt aatataaacc
     3541 gtgtaagtaa ccatcaatcc taggcgggtg gttgcttcac ggtttttatt tttctaaaat
     3601 aagatcaaga ggtgattaca cgatggctag aaagaaaaga aatcctgatg ctgagaagtt
     3661 agctgaatcc attttgaata cttatcaacc cgaatctgta gaggatatgc aagatgtttt
     3721 aaaagatgtg tttggtccct tatttgaaaa aatgcttcaa ggagaattga ataaccattt
     3781 agggtatgac gcccattcta aagagccaaa gaaacatgac aatcgacgaa acggttatgg
     3841 caataagacg cttaaaacga gctttggtaa agtaaacatt gatgttccca gagaccggga
     3901 ggcttctttt gaacctgagt tgattcctaa
//
LOCUS       DADGKS010000169         3850 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.175, whole genome shotgun sequence.
ACCESSION   DADGKS010000169 DADGKS010000000
VERSION     DADGKS010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3850
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.175"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(1..1155)
                     /locus_tag="JXV47_003007"
     CDS             complement(1..1155)
                     /locus_tag="JXV47_003007"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HAX1488975.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYSLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            1340..3781
                     /locus_tag="JXV47_003008"
     CDS             1340..3781
                     /locus_tag="JXV47_003008"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HAX1488976.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
BASE COUNT         1231 a          721 c          840 g         1058 t
ORIGIN      
        1 ttatattttg tagtaacgaa tatcattttc gatctttgta atcgaaaaag gtacatctga
       61 agtatattct gcacattctc cgtgttcagg aagcgtctca ctgaaaatcg tttcatattc
      121 gtcaacagtg atccgtgttc gagaatctag catctcttga tgagattgtg cgaagagata
      181 ttcttgatag ttttcttcca gataacctgt aaaaaattca cttactgcac cagaaccgta
      241 gctgaataga ccgatgcgat ctcctggctg tagtgatttc gaattttcca gtagagaagt
      301 tagccccagg tataatgaac cagtgtaaag attaccgatt cgtcggctgt aacggatgct
      361 ttcttcatag cgagccataa gacgttcctg attttcttcg tctgtttggt ctaatacgct
      421 ttgcaatgcc ttttttccca tcttagtata cggaatatgg aaagcaatcg cctgataatc
      481 ttcgagtcct cgacccgaca attctttatg tcgattccaa actttttgga atgattcgat
      541 atacgtagaa ttagataaag gaccatcaac aacaggaaat tcgctataat ctggacgcca
      601 gaaatcatag atatcttctg tcagaaatac gctgtcgtct tcaatcgata aaatacgcgg
      661 gttttgagtg atcatcatcg caacagcacc gacaccttgc gtcacttcac caccgcttgc
      721 caagctgtaa cgagcaatat cacttgctat gactagtact tttcgttctg gatgattttt
      781 gacatattct ttcgccatgt gcaaagctgc ggtgccaccg tagcaagcct cttttacttc
      841 aaaagaacga gcaaaagatt ggattttcag taaatggtgg ataattaccg cactcgcttt
      901 tgaatgatca atcccggatt ctgttccgac gatgaccatg tcgattagct cacggtcttt
      961 ttctgttacg attttgctgg cagcatttgc tcctagtgta atgatgtctt catttgcacg
     1021 attgactgcc atttggtctt gaccaatccc tatatggtat tttgcaggat catccccacg
     1081 gctttctgcc aactctgtca tatctaaata taaattagga ataaaaaagg aaagacgatc
     1141 aatccctatt ttcatttcaa cacctcttta cttatgataa aaaacttact ttactaaggt
     1201 atcataaaaa gattaaaaga aatataaaaa agagaatatt taaggattgt taaaatttaa
     1261 tcttagaaaa aaataactgg aacaagagct atttgttttt acagcaaaga atggtatatt
     1321 tttgtaggag gtggcttact tgaaagaagt cgttatgata gatgctgcaa gaacgccgat
     1381 aggaaagtat cgcggaagtt taagtccatt tactgcagtt gaattaggca cacttgtgac
     1441 taaaggatta ttagataaaa caaaactgaa aaaagataaa atcgatcaag taatatttgg
     1501 aaatgtcctg caagctggta atggtcaaaa tgttgccaga cagattgctt tgaacagcgg
     1561 tctccctgta gatgtcccag caatgacgat caatgaagtt tgcggatctg gtatgaaagc
     1621 agtgatctta gcacgccagc tgatccaatt aggtgaagca gaacttgtga tagccggcgg
     1681 aacagagagt atgtctcaag cacctatgct gaaacagtat cagtcagaaa caaatgaata
     1741 tggtgaacca atttccagta tggtcaacga cggattgact gacgcatttt caaatgcaca
     1801 tatgggatta accgcagaga atgttgcaac acaattttct gtgagcagag aagagcagga
     1861 tcgctatgcc ttgtcgtccc agttgaaagc agcacatgct gtcgaagccg gtgtattttc
     1921 tgaggagatc atcccagtca agatttctga tgaagacgtg ttatctgagg atgaagcagt
     1981 tcgtggaaat agtacattgg aaaaactggg cacgttacgt acagtattct cagaagaagg
     2041 aactgtaaca gcaggaaatg cttccccgtt gaatgacggt gcctctgtgg tgatccttgc
     2101 atccaaagaa tacgcagaaa ataataatct gccttattta gcaaccatca aagaagtagc
     2161 ggaggtcggt attgacccaa gtatcatggg aatcgctcca atcaaagcca ttcaaaaatt
     2221 gacagataga tcaggaatga atttatcaac aatcgatctt tttgagatca atgaagcatt
     2281 tgcagcttct tctatcgtag ttagccaaga actgcagtta gatgaagaaa aggtcaatat
     2341 atatggagga gcaatcgcat taggccatcc aattggtgca agcggtgcac gtatcttgac
     2401 tacattagct tacggattgc ttcgtgaaca gaagagatac ggtattgctt cattatgtat
     2461 tggtggaggt ttaggcttgg cagtcttgtt agaagcgaat atggagcaaa cacataagga
     2521 tgtgcaaaaa aaaaagtttt atcagcttac gccatctgaa cggcgcagtc aattaataga
     2581 aaaaaatgta ttgacacaag aaactgcgtt gatttttcag gaacaaacac tttctgaaga
     2641 gctctccgat cacatgatcg aaaaccaagt gagtgaagtg gaaatcccaa tggggatcgc
     2701 gcagaatttt caaatcaatg gcaagaaaaa atggattccg atggcaacag aggaaccatc
     2761 tgtcattgca gctgcaagta atggtgcaaa aatctgtgga aatatctgcg cagaaacacc
     2821 tcagcggctg atgcgagggc aaatcgttct atcaggaaaa tcggagtatc aagcagtgat
     2881 caatgcagtt aatcatcgaa aagaagagct gattctttgt gcaaatgaaa gttatccttc
     2941 aatcgtgaaa cgcgggggcg gtgttcaaga tatctctact cgggaattca tggggagttt
     3001 ccatgcatac ttatctattg attttttagt ggatgtaaaa gatgcaatgg gcgctaacat
     3061 gatcaactcg attcttgaga gtgtggcaaa caagttacgg gagtggttcc ctgaagaaga
     3121 gattctattc agtattttaa gtaattttgc tacagaatca ttggcttctg cctgttgtga
     3181 aatcccattc gaacgcttag ggagaaacaa agaaatcggt gaacaaattg ccaaaaaaat
     3241 ccaacaggca ggggaatatg cgaagcttga cccttaccgt gcagcaacgc acaacaaagg
     3301 gatcatgaat ggtatagaag ctgtagtggc agctacagga aatgatacac gtgcggttag
     3361 cgcttcgatc cacgcctacg cggcaagaaa tggattatac caaggattaa cagactggca
     3421 gatcaaaggg gataaactag ttggaaaact aacggtgcct ttggctgttg ccacagtagg
     3481 cggagcttcc aatatcctgc caaaagcaaa agcatcttta gctatgttag atattgattc
     3541 agccaaggaa ctagcacaag taattgctgc agtagggtta gctcaaaacc tggctgcttt
     3601 gcgtgcatta gttacagaag gaatccaaaa aggccacatg ggacttcaag ctcgttcatt
     3661 agcgatctca attggggcta ttggtgagga aatcgagcaa gttgcgaaaa aattacgtga
     3721 agcagaaaag atgaaccagc agacagctat acaaatattg gaaaaaatcc gggaaaaata
     3781 aaaaagcaat atctttagaa gaataaagca agatttacag ttattttatt tactgcagat
     3841 cttgcttttt
//
LOCUS       DADGKS010000170         3842 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.176, whole genome shotgun sequence.
ACCESSION   DADGKS010000170 DADGKS010000000
VERSION     DADGKS010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3842
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.176"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(34..735)
                     /locus_tag="JXV47_003009"
     CDS             complement(34..735)
                     /locus_tag="JXV47_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAX1488977.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(751..1191)
                     /locus_tag="JXV47_003010"
     CDS             complement(751..1191)
                     /locus_tag="JXV47_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HAX1488978.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(1191..1766)
                     /locus_tag="JXV47_003011"
     CDS             complement(1191..1766)
                     /locus_tag="JXV47_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HAX1488979.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            complement(2614..3093)
                     /locus_tag="JXV47_003012"
                     /pseudo
     CDS             complement(2614..3093)
                     /locus_tag="JXV47_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015510350.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(3252..>3842)
                     /locus_tag="JXV47_003013"
     CDS             complement(3252..>3842)
                     /locus_tag="JXV47_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAX1488980.1"
                     /translation="ELFQVSKITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSK
                     AASFTQILENSRYEVRKETLDLQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYF
                     VHYLPQEMMQFSREEFGKESLYRLLTKKGYTIDSFSDDFSAVFLTEEEQEILKTDAQI
                     GIKRIRKSSTQIGEMIEYSEAVYHTELHPYHIDYET"
BASE COUNT         1094 a          814 c          620 g         1314 t
ORIGIN      
        1 aatttttctt tcccgtcgtt tggtttttta tttttagcct aattcttgac cttttgcatg
       61 ctggttatcc gtaaaatatt ttccagcagg ctttccttcc aattcagcta atttttcttg
      121 gatctgacgg atcacctttt ttgcatcttc tggattttct acaaaatcga atttatcccc
      181 atccacttgt attttaggac atacatcaaa atcttcatac cattgattat agcgggtgtt
      241 caacgtttca taataggtat ataacgtctc atcgctttct agctgttcat agtcacgccc
      301 acgttttttg atacgttcta gcatcgtgtc caaagaaact ttgatatgga ccatcaaatc
      361 aggccgtttt tttggagcaa catcatctaa ctcgtttagc atcgtatcta ataagctatc
      421 gtactgctgt acttcgatat ccgttacccg acctaaatca gcgtttagat ggaacaacag
      481 gctatcttca tagatggatc ggtctagcac attgtcatcg ttcactaaag catttttcat
      541 tgctaaaaat cgcttgttca aaaagaagat ttgcaataaa aaagcgtact gctcaggatt
      601 tgaataaaag agcggcaata cttcgttatc ttcgacattt tcataaaatg gtttagaatc
      661 aatctctttt gcaagcatat ccgtcaaact gctcttacct gcaccaatcg ttcctgaaat
      721 caaaatcact gacatacaac ccttcctctt ctataagtac tcgcctacgt aagtttcaac
      781 aggcaatgtt tcaaaatcat attcacgtac agcttggtct gattttaaat acgtatggag
      841 actttgtgta atcatcaagt tcgtaggtac cgtctcttct tgtacaatga tcatcggttt
      901 tttcaacata gttgccacac ctaattcgta agccgttcct ggatcgattg tttgatgctc
      961 aaagtcaagg atagcaacaa caaattctgc atttgtcagt tcttccatat ctttttcgta
     1021 tacttcctgc gcccatccag cgctgaatag ttcataattg ctttcttggt gatgacgtgg
     1081 agagtagaaa cttgtgactg ttttgttttc ctccaacgct ttttcgatac gacttactcg
     1141 atcgatttgc tcctctgaaa aaaatggtcc tgctaaatat atttgactca ttattttgcc
     1201 tccttcaata ataactgatt tttaatagat actgctcgta attcattgac cagttccaat
     1261 ggattgttgg aaaagattac ttgatccaac cattttttat ccataaaatc ctcttttgca
     1321 aaagtttcta ataattgttg caagccgctg taataaccgc caatattcaa tattccgatt
     1381 ggcttgtcgg gcgtcagacc gattgctatc caagaaagaa gttgtgagaa ttcctccaat
     1441 gtacctagac ctccagggaa aacgaggaca gcatctccct tttcaaataa taataccttt
     1501 ctttcatcga tcgtttctgt aggaataaat gtagtaacat cttttccagg caattcagtt
     1561 tcaaaaagcc cattcggata gatacctgtg acttttccgt tattttccag tactgtttta
     1621 ctaatcactc ccataatccc ggagtatgaa ccaccgtaaa ccagttcgat ttcttcttgt
     1681 gccatgtatt ttcctaacgt ttgcgcaata aatttgtaac tttctttatt accaaaacgg
     1741 gaaccgcaaa aaacagtaag tttcataaaa aaacactccc taactcaaaa gtctatcttc
     1801 attctacacg tgttttttta aaataaaaga ctagattttg tagtttttta gtggtatata
     1861 ggatagacgc cactatatat agtatttaga aaaaaatcat ttttcagcca ttttatagat
     1921 aaaacaaaaa taaataacgt gttttcatcg atatgaaatg acttacttat agaagatact
     1981 gggatttcgt cctatatgcc aataacgtgt attattttaa acaacaaata cttgtttctt
     2041 ttattaacga aaaaatcatt ttgttctcgt gttatgtttc actgataaat gatgtttctc
     2101 taaataaaaa agccgacgaa ctaaacgatc aaaatttgat catttttgtt catcagcttc
     2161 tcctaaaaat ctttttgtta acgataaata gctggatttg taaaaatatc acttgaatcg
     2221 tcactgctgg aagaaaattc agtgataacc gcacctgttg cgcctgcctg gaactagtgt
     2281 ttgatattgg gctcgaacgt gtactgatct ctagcatgaa gaataatttc tttttttact
     2341 gtataataac tttctttcct ttttggaata gtacaggaaa gtttttttgt ttcctttcct
     2401 tcgacataag gtataccaga ccctttcgac aacgaaaggt tctcattttt ccttcatcgt
     2461 catttcaagg agggtgccga tgctctggac agtttcgatc gctcctaaac caaaatctgt
     2521 atattcgatt ctttctaact ctgattcttt cataccattc ctgtctcaag gtacatctat
     2581 tgtacttttt tcttgtaatc cattctgcct ctcctaacta attgtcaaat catcccaaga
     2641 tatgtcttct tcctcttttt cttcttggat gatttctgca ttcggatcta ctggtttttt
     2701 caataataaa atggttattc ctgtgacaaa agaaccagct aacaatgcac caatgaatgc
     2761 ccatggtctg gtcatcgtag cgactgcaaa cattcccgat gccggaatac ggctatctgc
     2821 gccccaaaac atgcttaatc cgccacctac tgtcccaccg actcccgttg ctatgacatt
     2881 gcgtgccaag tcgttcaata cgatagggaa acatccctct gtgatctgac agatccccat
     2941 aggaaaagcg gtcttcaatg tatcgatttc ttgacgattg agtatatttt tacgaatgat
     3001 tttccctaag aaataagcga tcgtcaagcc gaatggggtt accatcgaag ctaaaatcaa
     3061 tacagtgatt ggttcataga ttccttctga aaatcgtgcc acaccccctt atccagaata
     3121 aatggtaatc cagaaacagc cgtgtatctg cggtaataag cctaaccaaa cgaaaaatat
     3181 gagaagctat ttttgtttgg ctgttcttat tacttgatgc agggcagctt tttcacaacc
     3241 tcttttttta tttatgtttc ataatcaata tggtaaggat gcagctccgt atggtagacc
     3301 gcctccgaat attcaatcat ttccccaatt tgcgtagacg atttccgtat ccgtttgatg
     3361 ccgatctgtg cgtctgtttt cagaatttct tgttcttctt ctgttaaaaa tactgccgag
     3421 aaatcatcag aaaatgagtc aatagtatat ccttttttcg tcagcaaacg atacaaagat
     3481 tctttgccaa attcttctct gctgaattgc atcatttctt gtggaagata atgaacaaaa
     3541 taaatataag gctgattgtt caaataatat aagcgcttaa aacaaacagc ttgctcaccg
     3601 aaaaaggaaa acaaaggatc ttccttcttt atatggacca attgcaaatc cagcgtttct
     3661 ttccggactt catatcggga gttctccaag atttgcgtaa agcttgccgc tttggataat
     3721 cgattgtaag gacgattgct tagaaccgtc gtcccacgac cacttttctt tgcgacatat
     3781 tcatctgatg ccagcagttc gattgccttt cggacagtga ttttgctgac ttgaaacagt
     3841 tc
//
LOCUS       DADGKS010000171         3720 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.177, whole genome shotgun sequence.
ACCESSION   DADGKS010000171 DADGKS010000000
VERSION     DADGKS010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3720
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.177"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..355)
                     /locus_tag="JXV47_003014"
     CDS             complement(<1..355)
                     /locus_tag="JXV47_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488981.1"
                     /translation="MKKFKKKIYLGLVVGVSMFGFMAHTKQVTADTNQKERIMSQLDD
                     SQIEYVPNELIVSLKATQRISTEKNKPQNLLGVKVMVEKDLTLRINESDYNKRDQVLL
                     VKLNEEISVEEAVRTF"
     gene            complement(615..1163)
                     /locus_tag="JXV47_003015"
     CDS             complement(615..1163)
                     /locus_tag="JXV47_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488982.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(1164..2021)
                     /locus_tag="JXV47_003016"
     CDS             complement(1164..2021)
                     /locus_tag="JXV47_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAX1488983.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            complement(2307..2593)
                     /locus_tag="JXV47_003017"
                     /pseudo
     CDS             complement(2307..2593)
                     /locus_tag="JXV47_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(2583..2912)
                     /locus_tag="JXV47_003018"
     CDS             complement(2583..2912)
                     /locus_tag="JXV47_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAX1488984.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            complement(2989..3261)
                     /locus_tag="JXV47_003019"
     CDS             complement(2989..3261)
                     /locus_tag="JXV47_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAX1488985.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            complement(3261..3524)
                     /locus_tag="JXV47_003020"
     CDS             complement(3261..3524)
                     /locus_tag="JXV47_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAX1488986.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
BASE COUNT         1092 a          754 c          473 g         1401 t
ORIGIN      
        1 taaatgttct tactgcctct tccacactaa tttcttcgtt caatttcact aataatactt
       61 gatctcgctt attataatcg ctttcattta tcctaagagt caaatctttt tccaccataa
      121 cttttacacc caataaattt tgcggtttat ttttctctgt tgaaattctt tgtgtagcct
      181 ttaaactgac aattagctca ttgggtacat actctatttg agagtcatct aattggctca
      241 taatcctttc tttttggtta gtatctgcag ttacttgttt agtatgagcc atgaacccaa
      301 acatactcac cccaacaacc aatcctaaat atattttctt tttaaacttt ttcatctaca
      361 tctcctccta atagttttat tttagagtta gctctattac ttatttacta actcaacaac
      421 agattatcat acacttgtta atgaaatcac aatatctcat taaaacacac cctaaaatca
      481 taaccgttcc tatgctcatt ttttggattt tttaatcacg taaccagaaa aataaatccc
      541 ctctatttca cgcaaatcaa agaagaacta agtaactacc gtttaaaggt agttacttag
      601 ttcttctttg attattatct aactttatta ttcattcccc accctttgcg cagtgagtct
      661 tcggtatctt gttttatctg actggtagtt cttattattt ctccacgatc atctaattct
      721 ggaacaattg gatatttttc tctgaacaag tctagttctt tcaccacgtc attaaacaaa
      781 tcttgcttat cttcttgcgt aagattctgt ttaatatact catctaaagc ttttctaagc
      841 aattcatctc ttgtcatatt agtctcatac ttttctacta aaactctgga agtcgcattt
      901 aacaaagtcg acagttttaa aggatgcttg gtggaataaa ccttatcaaa ctttctgatt
      961 ggtgcgccaa ctttttttgt tcttcctcta ctctgtcttt caacattgga ggaagttttt
     1021 atttcttgaa cttggtgcac ttctaattgc ttattttcag atggtgtaat tgcttgctgc
     1081 tttttctttg cttctgcttc tttttttatt ttggcgagtc ctttgttgtt cccaaaaata
     1141 tcaagtcctt tgatgtcagc caattactcc acctccgcat accaattctc gtgttcttcc
     1201 aattctttca aaatactgat aaataattcg tggcttttgc gatcccattg ttttaagaga
     1261 cctttctttg tcttctccat cgtaatacct gatccgtcgt atcgttttaa gcgcgcattt
     1321 ttgagtacaa catttttaat caaatgttcc ccataaatct cttgggcttg tttatacatt
     1381 tcctgatcta ctgcgtcacc gctttccaac atgaaaggaa taacaccagc aacatataaa
     1441 tttgtatcaa attctttcac aaaaaagtcc atatactcaa gatattgcat cgcatttctc
     1501 atcgatttta cttgggtctg taagacgacg attgcccaat ccgcaatgta catcgcggat
     1561 ttactatata cagaaataga aggtgggaca tctaaataga tgacgtcaaa ctcatcaaat
     1621 aatggttcta gcttttcttt catatatttg aattgggata atgaatcatt atattggtct
     1681 ttgatccaat catcatacat ttcaaaggac atgtctgctg gaagtatata gaggttattg
     1741 attactttat agacagcctc tttaggtgga agattgttta tcaacacgtc agtcacagta
     1801 ttttcgtaaa caatcggttc accttctccg cctccttctt cgttagtgaa gttcatatgc
     1861 gttaagttca tcacatcaga agtatttcct tgcatatcca agtcaattat caaggttctt
     1921 tttccttcat taactgctga ttcaaaccct aacatttgcg cgcacgtact tttacctacg
     1981 ccacctttaa aattaccgat tacatatttc ttcgctacca cgttcctacc tcttttcttt
     2041 tagcaatatt catttgatac tattataaca tatttatttt tagttactac caaaaaaaag
     2101 atatatatgt actaccttat aattaataag taaaaggtag tacataaata aggaaaagct
     2161 gaaatatatt gatttatagc tttcctcaaa gtaatgacgt tatttaattt atcgagaagc
     2221 agagaatact cgcgacttta gtcatgtaga cgaatcagat tttcgataaa aaagaagccg
     2281 tccttcttaa gaacgacaac aaatcactag attaattttt tcaactgttc ataaaagttt
     2341 tcatgcgttc cacataacaa tactggaata accttgtttt ctataatctc gtaagctact
     2401 ctatatgttg tgcccgcata tttgaaccca ctagaccaaa tacctgataa atccccagtt
     2461 ttttgttcac ccttatatgg atcaatcgca atttcatcat aaattaaatt caaaaatttt
     2521 tctttcaatg gcttctcttt tagcttttta aatacttaat gacatgtttt gaaggaacga
     2581 tttcataagc caatttctgt tgccaactcc tctttagtca ttactttaga attagtaagt
     2641 gtatcttcag caatatctct aaaggaagaa tgcattttgt tttttctatt cttaaattct
     2701 acaagaatct catctttatc gtagccttct gcaattatat cagacaaaat atcttcgcta
     2761 aaatcataaa attctttttg tggttcaaca aattcataaa gaataccatt ctctaccaac
     2821 tttgcttcaa cttcgactcc attaggaaca ttaaaatctt taggtactgt caacatgatt
     2881 gaattgcctt gttttcttgt ttttgtaatc atttaaatcc ctcatttcta acagtatgta
     2941 attacttagt aaatacatta taccacgaga taatgtattt acaagtaatt actgtgactc
     3001 gtaatgcgtc cttgctgaat aaatttcaac cacgtgttca tcttcatcta ccttataaac
     3061 aacccggtgt tgtctattca atcttctaga atacctacct tcatgtgtag gttttaactt
     3121 ctcaaatgat tgggtaggga gatagggatc ttcctttaaa gtctgaataa ccttctcaaa
     3181 ttgaggtttc aaattagact gtttgatttt ctttaaatca gctttagccg agtttttaat
     3241 catcacagaa tagttattca ttataagtta tcccaatcaa tttcatcaac attagtaaat
     3301 ccactatcat ctttttctcg cttacgaaca acacccaaag tgcctatttg ctcaagtaat
     3361 agcgtttctt tgattgcttt ccaatcatcc aaaccaataa gcaccgcatt attttcactg
     3421 cgctcactaa tgatttcaat ttccgtatga ttctcattta catctttcaa caacttataa
     3481 aaatttttcc gtgctgagct aggatttaag actgtttttg ccatatctac tccccctcta
     3541 atttatatct ccattctaac gtacttaatt aagtacgtaa attcgattgt tttgtttaaa
     3601 ttggagtacc aaaacagcat tgtaaagtgt tatccgtttc ctttataccc gtggtgctag
     3661 ttaatttttt cctagaggaa aatgtctaaa catgttggta aatcaacaaa aaaacgcata
//
LOCUS       DADGKS010000172         3715 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.178, whole genome shotgun sequence.
ACCESSION   DADGKS010000172 DADGKS010000000
VERSION     DADGKS010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3715
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.178"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..205)
                     /locus_tag="JXV47_003021"
     CDS             complement(<1..205)
                     /locus_tag="JXV47_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488987.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESIS"
     gene            complement(222..1427)
                     /locus_tag="JXV47_003022"
     CDS             complement(222..1427)
                     /locus_tag="JXV47_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HAX1488988.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            2121..2507
                     /locus_tag="JXV47_003023"
     CDS             2121..2507
                     /locus_tag="JXV47_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAX1488989.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            2601..2792
                     /locus_tag="JXV47_003024"
     CDS             2601..2792
                     /locus_tag="JXV47_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1488990.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            3306..3638
                     /locus_tag="JXV47_003025"
     CDS             3306..3638
                     /locus_tag="JXV47_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAX1488991.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
BASE COUNT         1339 a          601 c          512 g         1263 t
ORIGIN      
        1 gactgataga ttctctagct tcttcacata aactttttac tttattaatt actactttgt
       61 catattcatt taacacacta ttattaccat tacttagacg ctcagattct acgaaacaac
      121 tcaaatcaga aatttcccaa aaaaattttt tgttaaaatc caatttcctc aactcctcca
      181 aactacgtaa atgatatagt ctcataataa aataaaacct ctcagctaat gttgttgaaa
      241 ttgtccacta aacctaattg atattgctta ggagatacac ctgcgtactt tttgaatact
      301 ctcgaaaagt gtgaagaatc tgaaaatcct aaacctaaag aaacttcact gatagtatgg
      361 tttgatttca acattatttt agccgtagaa atttttcgct tagagatata attataaatc
      421 gtaatatgca tttcattctt aaagctttct cttaatttag tttcacttac agaaaaataa
      481 ttagctattt cctttacagt aattctttta tagatattta agccgatgaa ttgaacgaca
      541 gaagaaatta agggagaaag atgctctatc ttagtttttc cgatttcctt agtataataa
      601 acaatcccag aatccctcac ttttaagacc tcaggtaacg atacagctaa ttcgttttct
      661 tgtatcaaag catctctact ttgatacgct tctattatat ccattcctaa tgttatagac
      721 gtttgtgcta acttttcaaa aacaatgata gaataatttt tttcagaccg aatcgtatct
      781 ccactaacac ttggaattat tccattactc agattaaaaa ccatgttttc taaatttcga
      841 atatctccat ttttaacata ttccagtatt ttattttcat aaagaaacag atatatttct
      901 ggatcgtaat tttgtgataa cagattatct attttgattt gctcgatagt tttacttaga
      961 ttttctgtat attcaattaa cggttcatgg aatagatctt ctatttttcc agtaaaaaaa
     1021 taatgaacta aaatcagaat atctcgaatg tctcctaaag aatacaaagt caaattttgc
     1081 aatgaattat agagtcgttc tctatcagcc attgcaacat tcaaattgtt catttttagt
     1141 ttaaaaaaaa ctttatcaat attatttgct ctaaatggac caaataagta atatctggtt
     1201 ttaaacatgt atagaagaaa catctcatta aaatcaccag taaagaaatg gaaatcttta
     1261 gtttttttaa tattatcagt tagtaacttt ttataatcat aaaaaaaata agtagttcta
     1321 tctgagcgat actcttttat aatactgaat tcggaattaa aaaccacgat aggtaacttt
     1381 aaacaaacat gaagagactt taataagact tctttatctg aaaacacttt tgtttctctc
     1441 tttcctttct acatcattaa atagtatttt atacgttatc taaaatacta ttcctctgtc
     1501 aaaataagct aacttacttc attataaaat atccacttat cgctttcatg tatattccac
     1561 cgtaaaaagt acattttatc accgagaact catcattttt catcatgatg aatactattt
     1621 acatatatct agttcaaaga caataattat tatgatccgt tattatctaa gcactataca
     1681 gataatagga atttttcgtt tctaaatatt ccaatttggg aatccaataa aaattttcgt
     1741 tcaaatacgt gtctattcga actcttttct agttgttaat tatgaagggg gaagaaataa
     1801 aaaatacaat ctatacacga ataagaatat tatccaaaag gaggttttag aaaagattta
     1861 ttatacgtaa aaagctcaag acattttctt agccataagg acatgtttga tatttaagaa
     1921 gatatatgaa ttttcttttc taagtataaa gataactatc cattatcaac taaaaaaaca
     1981 tttttgaaaa taaacatcag cagtcctatc aatgcatgtg agcttataga agttattcgc
     2041 agcgcagcat aattgcatta gcttcttttc gtgttttttg cctcttttcc ctttaaatct
     2101 taatggagga ggtgtgcaat atgtcagata acgacgaacg cgtaaatgcc cagttgattc
     2161 gattctttga aaaggtcatt ttgaacaccg ctaatactta ttataaaaaa caagaagaaa
     2221 ttcaaaaaca tgaacaactt gatcaactcc caccatattt gtttactaaa gatactataa
     2281 aatttaaaca accgattaat gttttaaatg tgactctcct tgttgaagat ataaaattag
     2341 caaaaatcct tcctttgttg aaagaacctg aacaaatttt tcttatcgaa aaatttatct
     2401 ttgataaaac tgataaagaa attggaaagg ttctggggat tacaagacag ggtgcgacaa
     2461 atttaaaaca tcgactttac aaaaaaattc aaaaaatgct ggtttaatat ctgcataata
     2521 actaattttg tatgcttctt tgctcgttct cctccttccc aaagaaatag attataagtc
     2581 catgggaaga aggtagattt atgaattctt taaaagaaga tttcatttta gcaaaggctg
     2641 gaaatgaaga agctgttgag gcaattctca aaagatttag ctctttgatt cataagcaat
     2701 cctggagaac tggaaaatat gatcaagatt gttatcaaga atgtatgctt gcaatatatc
     2761 tagctatctc gaaattcgaa attaaagaat aactcaacta agggagtctg tgacataagt
     2821 aaaaagatag tttcaaattt cgaacaataa atttgaaact atcttcttta taattataaa
     2881 gtatcgattt tacagcgttc tataatgatt catagaatct aaaacgaatg attttaatta
     2941 tcaacgtttt ttaattcgtt tttagcttaa aaataacttt tgtcacagtc tcactcctaa
     3001 aattacttta tttacgtatg aagtgggcag gaggtcgaat ccagaactgg gctatggtac
     3061 ttcaacgagg acttctcctc tagaattgaa aagcatgcga tttaccttcc gtaacgacgg
     3121 tagatttatt caactatgtg tccaatcaaa atttgtctga tttcaaaaat agtcaagaga
     3181 attttggttg ttaaaaactc ttatctatca acttccacag tttagttgac aaaccctgat
     3241 actaagttgg gctatgatac acttttcttg actatcagtt acgttaccgg aaggaatgaa
     3301 ctctattgag aaaaacatat gatcgtaaat ttaaactaaa gatttcacag gatatccttg
     3361 agaaaaaagt aactaccaag aaaattgctg aagaatacaa tatctctcgt ccaacaattt
     3421 cccgatgggt ttcagaatat cgtcgatacg ggaaaaatgc ttttgctgga caaggaaaaa
     3481 gattacctga taaagcagat ttctacattc ttgaacagga aaataaacga ctaaaagagg
     3541 aagacgagtg ttctacgaac acaaagatcg atacggatct ccagggatca ctcaaaaact
     3601 ttacgatgaa ggaatcgaaa tcaataaacg tgttgtagct gttcttatgc gtgaaatgaa
     3661 tttatgcaca agaggatttc atcgacgcaa atcttctcat ggtagagaaa aaaca
//
LOCUS       DADGKS010000173         3572 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.179, whole genome shotgun sequence.
ACCESSION   DADGKS010000173 DADGKS010000000
VERSION     DADGKS010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3572
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.179"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..2199)
                     /locus_tag="JXV47_003026"
     CDS             complement(<1..2199)
                     /locus_tag="JXV47_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1488992.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESLSESFNEARSSEPSITQESQIER
                     QEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVRVPRASIGLIEF
                     IRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITFEVAFFQSGGTE
                     PNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGNLGNLLIDGQDV
                     TNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREPISGGVRIAEVT
                     NPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYALEVTDVDLFNE
                     GRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNVINLNENELTYT
                     LHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRFSANNTIGGPTS
                     FTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKVIKTDENGQRLA
                     GAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYLLDATVHDVFIN
                     EYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGETLQTG"
     gene            complement(2871..3139)
                     /locus_tag="JXV47_003027"
                     /pseudo
     CDS             complement(2871..3139)
                     /locus_tag="JXV47_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT         1024 a          781 c          551 g         1216 t
ORIGIN      
        1 accggtttgt agcgtttctc cttctcggtt ctgtaactca aaaacagctc cttgaaggac
       61 ttcaccactg ccttcagcat gtttaattag ttcaacacca cccgtatcaa ggatgttttc
      121 aatggttaac gtcacttctt ctatggagta ttcatttata aaaacatcat gtaccgtcgc
      181 atctaaaaga tacccttccg gtgcttctgt ttctcggact tgatagctac ctacaggaag
      241 cggttcactt aaaaattctc cgttttctgc cgttatacct tcttgtatca cttgtgaatc
      301 gcttgataaa atttcaaatt ttgctcctgc cagcctttgg ccattctcat cagttttaat
      361 tactttaata cgcccatcga ttttccttgt tcttacagta ctcgtattca atcgattgtc
      421 actattcaca agcgttgcaa agtttaaaat ttgatcgccg accgcatacg cctctacatt
      481 gaccttaaaa gagagggtaa aacttgtcgg accaccaatc gtattattcg cactgaaacg
      541 aactattcca ttattgactt cggcatcaat gaaagaggga atatctgata gaaatgacac
      601 aaattccatg ccttcttcca aaacatcttc aataacaagc gtatttcttg ttccagaaaa
      661 catcgagaca tgcagagtat acgttagttc attttcattg agattgataa catttttgtc
      721 cacacttttt cttaaagaga ttgccggaag attactttca gggattctca agcggtagtc
      781 tcggctcatt acctgattat tgtaggtcat actcgctcga ttccgagaaa acccatcctc
      841 ttgtcttcct tcattgaaca agtcgacatc ggtcacttca agagcatatt caataaaata
      901 cgattgaccc tctgctagat taccaaagtc cacaacaagt gtattcgttt ccttattaaa
      961 agatactttg tccacaaatt cctcggaaac ataatgagtt ctaacgtttg cttcacctgg
     1021 attcgttact tctgcgatcc gaaccccacc tgaaataggt tctctatttc cagtggaact
     1081 ccatgtagtc ggattcggtg ccaaagttgt tccttgcggt agtacatcgg taaccactac
     1141 accgtctttt cgtgatcctt cataatttac ctgcaaaata aatttattac tgttggtcac
     1201 gtcttgcccg tcaatcagca gattcccaag atttccttgg ctgtcgattt ctctagagcc
     1261 atagtataat ttcgaaaaaa tgggtcttga tgaaggaata ggcgtaattg aaaattccgt
     1321 gtttgctgct cgctcagcat aagtaagact cacttgaaag tcattatttg gctcagtacc
     1381 gcctgattga aagaaagcaa cttcaaacgt gatactgaat gtatacgact gagcggcttc
     1441 atttaatcct tcataatcaa aggtaaatgg aaaaacaacg tctgtgcctt cttggtaaaa
     1501 tgccagtggc tttaaaggtg aatcatcagc gacctccact ctaatgaact caattaagcc
     1561 aatcgatgct ctaggaactc gtacgaccat ctccccatat tcttcaagaa tatcgccagc
     1621 gcctccttga atgtatccct ttaacgtttg tgtatgcctg ctcggcaaag tggggcgctc
     1681 agcagagatg ccgatgtcat aattcaagag ctcctcttgt ctttcaatct gagattcctg
     1741 cgttatagat ggctcagatg atctggcttc attaaaagat tcacttaagc tttcttctgg
     1801 tacattaaaa gactcacttg tgctttcttc tggtacactg atttctattg agaccgtatt
     1861 tgattgaata tcaccgcttc ttgcggtcaa ttcgtattta cctgaatgct gggaagaata
     1921 agtaatcaga cgttcgtaat cattgagttg cttcacttcc ccttcaatca aatcctcact
     1981 cttatcaatg accaatgcat ttagcaggtc tggtgttcct ctgactcgca actggaactg
     2041 ctcacccaaa gcagcctcct cttgatcaac ttcgatcgtc agcgaacgct ctggctgttc
     2101 tgctaaagac tcagctagaa ccgttatgtt cccaaattga ttgatcacaa taagcataac
     2161 tagaaacata cttaacagtt tatgaaattt gttcctcact attactcccc cttataattt
     2221 tgactaaaca acaaggtacc cgataatttt ctaaaaagat tccccaactc aaaatggctg
     2281 cgttacctcc ctcgtatttt cggttcaact caagcgttgc aatgtaagct gtaaacaaag
     2341 ctaatgattg ccgattgtct tctgttgatt gattcgatag ctttgtatga cttttagttg
     2401 tccgtgtggc ttaaccataa ttatgatttc acgattcctc ctgccagtgc cttgcacaag
     2461 ctggagcgta accctaatag ttattttgtt aatgtactta tatactttta tacttttcca
     2521 ttagaaacaa tcactaaatc gttgatacca aggtcagact ctagaatttc atcagtgagt
     2581 ccctgtattg gttaaccttc atcaatccca aaaaaatata tcaatgctta gcatcaaaat
     2641 gaatatatag tttagaatac ttgggattca tcgataactg atcgcttatt tggccatatt
     2701 atttggcact tggttcaact aaacgcattt aggatgttcc ttcattctcg tcatggatgt
     2761 tctcaaaccg tcattactaa taaactgtcc accgaatcga tggttcattt cttgcatttt
     2821 ccacgtccaa ttactctttt tgctctttat ttgggcgtag tttcactttc ttaacttgta
     2881 tcgtcttcca tcaactcctt aatcatcttc ttagctttat tggctcggtt tccttgtaaa
     2941 aggtatctac aaatagtgac aatctgtatt aaatcttcat cattttctgt aatgtcaata
     3001 atttctatat tctgtaccat atattgcaaa gggtttcact aagttcataa ccgaagcgaa
     3061 ttaaacaact tttgtataga ataactacct tttctatttt tccattggta attctatcta
     3121 ttaattggtt taatcctttt gttgtagttg attccactac caagatgatt ctctcgaatt
     3181 ttaaagcttg aagatgtatt gctatttttg ctaactggcg tatttgcaac tatttttccc
     3241 ttctattctt ccttcattga ttcccctcta aaattactat ccataaaaaa ttgcataaat
     3301 gacaatagta tttatattag tcatactgct ttttaacaca gcaaattcca gaaaaacatt
     3361 cgttacatat ttgtgaattt ttccaaaaaa taacattttt ataaaacgac gaaaaataaa
     3421 tcactaccag tcaacttcta taatattacc aaataacaaa ctaactatcc atcaataacg
     3481 tgttttattt tttaaaattt ctataaaaaa acaatcattc ttaaaaagaa tatataaaaa
     3541 taacaataac ctttgtgatt tttcttgttt ga
//
LOCUS       DADGKS010000174         3454 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.180, whole genome shotgun sequence.
ACCESSION   DADGKS010000174 DADGKS010000000
VERSION     DADGKS010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3454
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.180"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(116..391)
                     /locus_tag="JXV47_003028"
     CDS             complement(116..391)
                     /locus_tag="JXV47_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1488993.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            623..1357
                     /locus_tag="JXV47_003029"
     CDS             623..1357
                     /locus_tag="JXV47_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1488994.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            1396..2538
                     /locus_tag="JXV47_003030"
     CDS             1396..2538
                     /locus_tag="JXV47_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAX1488995.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(2633..>3454)
                     /gene="sufB"
                     /locus_tag="JXV47_003031"
     CDS             complement(2633..>3454)
                     /gene="sufB"
                     /locus_tag="JXV47_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HAX1488996.1"
                     /translation="KVDVPLQTYFRINAENTGQFERTLIIVDEGASIHYVEGCTAPTY
                     SSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKAYEGATVEWIDGNLGAK
                     TTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAPNTSSSIVSKSISKDGG
                     EVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEIHNSQVSLEHEAKVSKI
                     SEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVELNRLISYEMEGSVG"
BASE COUNT         1182 a          600 c          615 g         1057 t
ORIGIN      
        1 aatcattgat gtttccattt gtgtttcctc cttataaaat tctgttaaag actaaaacat
       61 acagataata aaaacaaact ctttattact atatgtttta gtcttatttg tttactcaac
      121 ctttataccg ttccatgaaa ctatcaatat cagatttttt aaatctaatg accgtatcaa
      181 tttttataac aggtaacccg tattgagaaa catattttct aatcgttcct actgatacac
      241 ctagatattc acttgcctgc tgatagtcca tatactctag agtgactcca gaaataatgt
      301 cttctagcat aggctttagc actgtaatta tctctttcac ttgttgttca acttgtatag
      361 aaacaatgct atcaatgatt tgtagagaca tatttccccc tcctttcgtg attgcttgaa
      421 caaattttct aagaattatc ttcgtatttt ttgctcaaaa taaaagtatt ttgttattaa
      481 ccgattaatc aaacaaaaaa tgattaccag ttcatcgaca tacacataat acctcgataa
      541 aaaagaggtg tcaatatctt tgtaaaattt atttacaaca cccctttttc gaggtatact
      601 aattttagga ggtgtggtca atatgataaa acgtccacca ataaattatt tagaacgaaa
      661 aaagatactc ggaacaaaaa taaaagctat aagaaagagt aaaaaattaa cacaaccagc
      721 atttggtctt atgattaaca acggtcaatt aattgacaaa aaaactatct acgaatggga
      781 gaagggaacc tatttaccaa taccagagcg attatcccga attgctgatt tgggaaatat
      841 gagtatagag gagttagttt gtggcaatgt agaagaatat attttgggaa ttattcttta
      901 tagagatagc attgtactag atggtataac atttccagat aaaaacctgt tccagcatct
      961 tcgtcaacag ttcccaccag tacactctaa tttagataca tggctggata gatattccaa
     1021 attagaacca gagatgcaag aatttattgc taacaagact tgtaataaag ttaaaaatga
     1081 aaaaattagt cttttcaata tcttaaaaat agaagaatta ttcatcaatg ctattgtaga
     1141 agaatttgac aataacattc ttttcctcac tagcagtata gaagaactac tagaaagaat
     1201 ggtagatgaa tggctaccta ttcaattgaa agacatgtct tatcccgaag aagctgtgag
     1261 agaaattact gataatataa acaagctaga acaaacgatt tcatcaattg ggaaaaaata
     1321 cactaagaaa aaaatgaagg gaggtgatac catctagtgg taagtactcc ttgtaaacta
     1381 agaggagatg atttcatggc aaaaatatca aagtacaaaa agaaaaacgg tcaagtggcg
     1441 tggatgtata aaggacacat tgccaccgat ccacgaactg gtgaaaaaat aaatactacg
     1501 agaagaggtt ttagtagcaa acaagaagct caaaaagatt atgacgagta cagacatcaa
     1561 atattatacg gtgttaaaaa gaaagcacct gatatgacat ttgaagacct gtataatgaa
     1621 tggataactc atcagcgtac cagtgttaaa gcttcaacaa tcgcaatctc agtaagatac
     1681 gcaaataatc aaatacttcc agcatttggt aagcttaaac tatcgaatat ctctgtccca
     1741 tattgtcaaa aagtggtaga tgaatggcac agtaaatatg aaagttacga ttatatgaga
     1801 aaacagactg cacaaatttt acgctacggg gttgcaatgc aatatattga caataatcct
     1861 atggaaaaaa cacttcttcc acgaaaaaaa gagtatgaga aaaatcgtaa attttactca
     1921 aaagaggagc ttaataattt actggatgct tttaaagatt ttggtaacat gaaacaatac
     1981 gccttcttca gattattggc atacacaggt atgagaaaga gtgaagtact cgctttacag
     2041 tggaaagaca tagacacgtt taataaagaa ctacatgtca ataaaactct tgctgtagat
     2101 gaatttggta aagttataat tcaatctccg aaaacaagag cttctagacg agttatctct
     2161 ttagatactg agactctttc tatcctcaac aactggaaat tacagcaaaa agaagagtat
     2221 ttaaaacttg gatacaatac tagctctaaa gagcaacatg tttttacaac agttaaaaac
     2281 actctataca ttccaaacac tgttaatgat tggttaagat atattttgaa aaaatataac
     2341 ttgcctcgta ttacacctca tgggtttaga catacacatg ctagtttatt attagaagca
     2401 ggagaatctg tcaaggtagt tcaacaacga ttagggcatg aaaatagtaa agtgacatta
     2461 gacatctatg cacatattac aaataatgca cctaagaaaa caggtcaaga ctttgctgat
     2521 atgatggctc atcagtaaaa gagctggtca aaatctggtc atttctagta tacaggcaaa
     2581 acaaaaaagc tagaaccctt atatatcaag ggttctagct cctataacag gtttacccaa
     2641 cactgccttc catctcataa ctgatcaatc gattgagttc gactgcatat tccattggaa
     2701 gttctttggt gaatggttca acaaagccca tgacgatcat ttcagttgct tcagattcgg
     2761 tcaggcctcg gctcatcaga tagtagagtt gttcttctga gatttttgag actttggctt
     2821 cgtgttctaa agagacttgg ctgttgtgga tctcattgaa tgggatcgta tcggatttcg
     2881 accattcgtc catgatgatc gtgtcacatt cgatatgaga gatcgaaccc gcactgtttt
     2941 tggcaaaggt tacttgtcct cgatagttta cttctccgcc gtcttttgaa attgatttag
     3001 agacgataga gctagatgta tttggtgcat tgtggatcat ttttgcaccc gtatcttgga
     3061 tttggtttgc tcctgcaaag gcgatggaga gcatggtgcc tcgtgcacct tttccatcta
     3121 agtaaacact tgggtatttc atcgttgttt ttgcacctag gtttccgtcg atccattcaa
     3181 cggttgcgcc ttcgtatgct tttgctcgtt tggttactaa gttgtacaca ttgtctgacc
     3241 agttttggat cgttgtgtaa cggcaatacg catcttttct tgtaaagatt tctacgatgg
     3301 cggcatgcag gctgttactt gaataagtag gtgccgtaca accttcgaca tagtggatgc
     3361 ttgctccttc gtcaacaatg atcagcgtac gttcgaattg ccccgtgttt tccgcattga
     3421 tccggaagta cgtttgtaat ggaacatcga cttt
//
LOCUS       DADGKS010000175         3400 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.181, whole genome shotgun sequence.
ACCESSION   DADGKS010000175 DADGKS010000000
VERSION     DADGKS010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.181"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..140)
                     /locus_tag="JXV47_003032"
     CDS             complement(<1..140)
                     /locus_tag="JXV47_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HAX1488997.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVG"
     gene            complement(141..791)
                     /locus_tag="JXV47_003033"
     CDS             complement(141..791)
                     /locus_tag="JXV47_003033"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HAX1488998.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(804..1703)
                     /gene="rsgA"
                     /locus_tag="JXV47_003034"
     CDS             complement(804..1703)
                     /gene="rsgA"
                     /locus_tag="JXV47_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HAX1488999.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(1868..>3400)
                     /locus_tag="JXV47_003035"
     CDS             complement(1868..>3400)
                     /locus_tag="JXV47_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HAX1489000.1"
                     /translation="PEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVTIALKH
                     FQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPARANEEK
                     WQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKKKGQKK
                     WWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVATKTEE
                     IADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAEASLKE
                     LGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVTLSSHV
                     GENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYINFVVS
                     QGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGAGTTIT
                     KGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSASTSES
                     SK"
BASE COUNT          847 a          746 c          657 g         1150 t
ORIGIN      
        1 cccactgcca gatctactgg gtagcctgct tgaagcaggt acagcgcacc acggtctatc
       61 ccgacatagg catcgtattt ggacagcaga gactgcggcc agttttgcgg attacctcca
      121 gcagctaata aaattttcat ttagtctaat gcctctttta atcgttcgat ttgtccgact
      181 ggattttcgg ctccatagat atatgatcct gcaacgaaga catccgcccc tgcatcttta
      241 cagatttttg ctgtttctgg aacgattccg ccatctactt cgattgcata agtccaattg
      301 ttctctctac gtagatcagc gagttccgta attttttcta ctgtttcttc aataaagctt
      361 tgtccgccga acccaggatt gacagtcatg actagtactt gatcagccaa aggcaaaaca
      421 tgtttgatca tggagactgg tgttcctgga ttgataacta ctccagcttt aactcctaag
      481 ctttttgtca tttgaagtgc ccgatgaata tgaggagttg cttcgacgtg gacagtaatg
      541 atatctgctc cagcttttgc aaatgctgga atgtagtttt ctggatcaac gatcatcaga
      601 tggacgtcta acggtaattt agtaacagga cggattgcct gaacaatatt tggccctaat
      661 gtgatatttg ggacaaattg gccatccatt acatctacgt ggatgtaatc tgcgcctcct
      721 ttttccacta actcaatgtc tctttgtaaa ttggcaaaat ctgcactcaa aatggatggt
      781 gctatcttca ttcttgtttc ctcctatttt cgtttacctt ctttttttgc atacattggt
      841 tttctttttt cgatttcttg taagaattgc aaataattgt cgtaacgtgt ctgtgcgata
      901 ccacctgttt ctactctatg ttttacttcg cagccaggtt ctttagcatg catgcactct
      961 ctaaatttgc aatggacaga agcttctaca aattcaggaa attgtctcgg cagttctcct
     1021 gcttcaattg tcaaaaagtc aatcgagcta aatcctggtg tatctgctac taacccgcca
     1081 tagataggaa tcagttccac atgacgtgtt gtatgccgtc ctcttccaag tgcatcagaa
     1141 atctctcctg ttgctaaatt cagttccggt gatatttgat tcagtagcgt cgattttcct
     1201 gctccagact gacccataaa gaccgatagc cgttctggga agtaacggat cagttctgtc
     1261 gtatcacccg tatgattggg tacaatcacc ggatagccta ttttagtata ggtttgcttg
     1321 atctcttcga ttttttctgg gtcgtctgac aagtcggtct ttgtcaaaaa aataatcggt
     1381 tcgatcgact cgtattccaa ggtaactaga aagcggtcaa gtagattata agaaaatgca
     1441 ggctctacga tacttgtgac aatgattcca agatcaacat ttgtgactgg tgggcgaact
     1501 aattgatttt ttctcggcaa gatttccaga agatagccgt ctgtttgatt ttcactctca
     1561 aagatcacct gatctccgac aagcggcgtg attttccgat tccggaaatt tcctcttcct
     1621 cttgtttgat aggtctctcc gtttgcgtat acatagtaaa aaccgctgat tgcttttctg
     1681 atttgtcctt tgataagtgc cacctccgtt tttgtttatt ttaccatacg aagaggaaag
     1741 taggtgttat tccatgcaaa cttctcaaag tatatggctt gaaaattgat caaaagagat
     1801 agaaacacaa aaaagagaat gcaacaaatc aatgtcgcat tcccttctga tatattttat
     1861 tcagcactta ttttgaactt tctgaggtgc tagctgatga acttgtggag ctggaagatt
     1921 cttcttttga agagttgctt gtgctactgg agctacttga gctgctagaa ctgtctgaag
     1981 agtctttttc agaactagaa gacgctggat ctggtccttt agagtaaatt acgttcacaa
     2041 ccattccttt ggtaattgtc gttcctgccc ctggtactgt acgaatcact ttatctttat
     2101 ccaccgtgtt tgaatattcg gaagtctcat gcccgatata ttctgcaccg acactagcta
     2161 aataactttg tgcttcgctt tttgtatagc cggagatatc attcaattta ggctctgttc
     2221 cttggcttac gacaaaattg atgtaagttt cttctgctac aacttcaccc gaggctggat
     2281 cctgactgat gatcgaacct gatggtacag tgtcgctata gtcataagta gcactaatat
     2341 tattgatatt gaatccttgt gtaacaagcc aattacgaac agtttcgtag ttttctccta
     2401 catgactact caaagtcact gtttctggtc ctttgctgac tgtgaaagta atcgtgtctg
     2461 ttttaggatc gacttctgta tcttctgatg gagattgcga aatgatcatt ccgctttcta
     2521 cctctgaact gaattcctct tctttttgaa tcaagtcagc agaaaaccct aattctttca
     2581 aacttgcttc ggcatcttca taacttttac cactgtaatc atctaatttg atttttttcg
     2641 tgccgctact aatatacaga gtgacttcgc gtttttgctt gactgtcgtt cccgctgccg
     2701 ggtctgtctt cactacatta ccttcttcga ttttgtcatc tgcaatttct tctgtttttg
     2761 ttgctacttc taatttcgct tttgcgagtg tttctctagc agaagcttca gaaagatcag
     2821 aaacatcagg aacaacaact tctcctcgcc cgccagaagc aaagaataca gctgttccga
     2881 ttcctaaaac agcaagaata gctaatagga tcagccacca ttttttctgt cctttctttt
     2941 taggatcagg cagaacttct tcctcctctg gtaaggtttc gttttctggc ttgtcttttg
     3001 gcagaggcat agatttgaat gaatcaggca ttggtgcatc ttccgtaagg ggtgtgataa
     3061 cttttgtttc attatccatc acatgaggct gccatttttc ttcgtttgca cgagctggtg
     3121 ataatactgt agaaagatca tcagacattt cctcggctga cttataacgg tctgcaggtt
     3181 ctttagccgt tgcccgtaaa atcacgtttt ccagtgcttg tggcacattt ggatcaagtg
     3241 cttttataga tggaagatca tcttgaaaat gttttaaagc aattgttaca gcagattcac
     3301 catcaaacgg tacgctaccc gtcaacatct cataaaggat gatccctaaa gcataaatat
     3361 ctgactgctt cgttgccata cttcctctgg cctgctcagg
//
LOCUS       DADGKS010000176         3232 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.183, whole genome shotgun sequence.
ACCESSION   DADGKS010000176 DADGKS010000000
VERSION     DADGKS010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3232
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.183"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            10..615
                     /locus_tag="JXV47_003036"
     CDS             10..615
                     /locus_tag="JXV47_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAX1489001.1"
                     /translation="MAKTTTVTTFDNISIKRISFNFKNATNAISTDCNGQLDGETEMQ
                     RIVKKCGSTEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDERIKSGIYSYGPDSVG
                     EDFSLAAEIVDDFEEKNKLIGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFGK
                     FYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            635..997
                     /locus_tag="JXV47_003037"
                     /pseudo
     CDS             635..997
                     /locus_tag="JXV47_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1000..1182
                     /locus_tag="JXV47_003038"
     CDS             1000..1182
                     /locus_tag="JXV47_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489002.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            1200..>3232
                     /locus_tag="JXV47_003039"
     CDS             1200..>3232
                     /locus_tag="JXV47_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HAX1489003.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASEAEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLSKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTL
                     IIGAVITAIAGVIAIIKNWGAITDWFKGIWSKFTDWLGGTWESIKEGASSVWDG"
BASE COUNT         1204 a          479 c          692 g          857 t
ORIGIN      
        1 ggaacaacaa tggctaaaac aacaacagta acaacttttg acaatataag tattaaaaga
       61 atttctttta attttaagaa tgcaacaaat gcaatttcaa ctgattgtaa tggacaatta
      121 gatggcgaaa cagaaatgca gagaattgta aaaaaatgcg gttcaacaga agtaaaatcg
      181 aaatctaaac caatcaatat gacggtaaca attactgcac atgtaccgat ggaagtttat
      241 cgacgcttca atgggttgaa acaagatgaa cgtattaaat cgggaattta ctcttatggt
      301 cctgattccg taggggaaga tttctctctt gctgcagaga tcgtggatga tttcgaagaa
      361 aaaaataagc tgattggtat gttagcatgc acttcgaata caggattaac attctctatt
      421 gaaaatggtg cggatgaagt agctgcgtta gaactagaaa caaaagttat gcaagatgaa
      481 tttggtaaat tttatcatga agcaattgtt gcagaacttg aagaagactt aacagatcaa
      541 tggatgacga atctatctgc tgatgtgatt aaaaaaactt cagttgtgac aactacggcc
      601 actcaatcac agtaaaaaaa acggaggtag cgaaatgaac gaagattact caaaaattga
      661 actaaacgat ggaacaattt tgaatttaga acctaaactg aatatcaaga aattattgat
      721 gatcaataga gattttaaca cagacgagtt tgcaaaaatg tcgatgggaa aaggctctat
      781 ggatattaca gttattcaag gtgcaaaagc cgtatatgta gcttatcgtc aagcgaacat
      841 ggtcgattac atttcattcg atgaatttat agataaatga gattttgata tggaggttgc
      901 agtagctgta tacagtacta tgatgttcaa acaagcacgt gatgcctatc aaaaagaatt
      961 cgaaaaagca aataaggaaa aaaagcttca aaagtaaaaa tgccaaagct cttagttgaa
     1021 acgtgggtcg atgtctattc gatgttgacc gacgtttttt ctatgccttc agatttggtt
     1081 ttaagcgata tctgtttaga tgacattttg caaatggctt acaacaagag cgcttatgaa
     1141 ggatggaaga actatgcaat aaatcaatcc cagaaaaact aaaggaaagg aggtaaaaaa
     1201 tggctaaaaa gagaacggaa gcagaagtaa ctttcatagc taacgatgac ggattgaaat
     1261 ctacgttaaa agaaatcagt gctgaattaa ctaaaaatag agcagaatta aaactagaac
     1321 aagctcaatt gcaacagact ggttctgaat cagacaagtt aggaagtaaa ttatcttctt
     1381 tagaaaagca gtatgaatta caaagtcaaa aagttgaagt aactagccaa cgtttagcca
     1441 atgcgaaaaa atattatgga gaaaattcca ccgaagttca gaaacttgaa agagaactga
     1501 ttaatcaaca aacagcgcaa caacgtttgt caaacgaaat tgataaaacg agtaatgcac
     1561 tagctcaagc aaaaggcgaa atacagacgt acgagtctac aatgcaacag ttggatagcg
     1621 aacaaaaaaa tgttcaagct agtgcttctc tgattgaatc cgaatacaaa aaatggcaag
     1681 caactgctgg tcaatcagct tctgaagccg agaaattagc gaaagcccaa gaatatgttt
     1741 ctcaacaatc tgaaaatgcg gagaaaacga tagatatcct aagacgacag ttagaagcta
     1801 cacagtctga atttggcgct acatccacag aagcaatgca gatggaagcg aagcttaatg
     1861 atgctgaacg tgaatttgaa gagttaggac aagctgctaa aaatgtagat acaactaact
     1921 tggacgatat cggaagcaaa atagatatga ataatttaat ggaagcttct gacgttttaa
     1981 gcgacattgg cgataagctt acagaattag ggaaacaagc agtggactct gctaacagtg
     2041 taggtagttc ccagagtaag atacaagcta attttggttt gtctaaacaa gaggctgaag
     2101 aattaacgaa tgtagccaga gacatttatt ataaaggttt tggagaatcg ttagatcagt
     2161 ccacagatgc attgattttg gtaaagcgta atttaggaga tttaaataat caagatttac
     2221 aaaatatcac ggaacaagct atggtcctag aaaacaccat gggcgctgat atggatgaaa
     2281 cgttacgtgg tgtaaatggc ttaatggtca atttcggctt gagtgctcaa gatgcaatgg
     2341 atttaatggt ttcgggtact caaaacggtt tagataaaac gcacgaatta ggcgacaata
     2401 tggcagaata tagccaatta tggagtcaaa tgggatattc agctgatgaa acgttcggaa
     2461 tgcttcaaaa tggtttagat gcgggtgctt ataaccttga taaagtcaat gacttagtta
     2521 aggaaatggg aatatcgtta acagatggtc gatttgagca aaacatggat atgtttagtg
     2581 aaagtactag aaaagctttt gaagagtgga aaaatggcgg aggaacacaa aaagacgtta
     2641 ttaattccat gattcaagat tttagcaata tggatggtca atacgaccaa ttaaataaag
     2701 cttcgacaat ttggtctgcg cttggcgaag ataatgcgat gaaagttgtc caatctttaa
     2761 ctgatgttaa ccatacattt gatgatgtta gtggatctgc acaaaaaatg aatgaagatt
     2821 ctactactcc gttacaagaa ttaaacggaa aaatagctga attaaaggat tcattagctc
     2881 ctataggcaa cacaatcata gatgcactcg aaccagtaat tgattttcta ggaaagatgg
     2941 ctgatgcgtt taataatctt ccacaaccag tacaggatta tgccgtagcg attggcggat
     3001 tgactgctgc atttacttta ttaatgccaa taatagttgg cttcatggct ctaggtggtc
     3061 ctactacatt aataatagga gcagttatta ctgctattgc tggagttata gcaattataa
     3121 aaaactgggg cgcaattact gactggttta agggaatatg gagtaaattc actgattggt
     3181 tgggtggtac ttgggaaagt ataaaagaag gtgcctcatc agtttgggat gg
//
LOCUS       DADGKS010000177         3199 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.184, whole genome shotgun sequence.
ACCESSION   DADGKS010000177 DADGKS010000000
VERSION     DADGKS010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3199
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.184"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            301..585
                     /locus_tag="JXV47_003040"
     CDS             301..585
                     /locus_tag="JXV47_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489004.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            588..1004
                     /locus_tag="JXV47_003041"
     CDS             588..1004
                     /locus_tag="JXV47_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489005.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(1141..1860)
                     /locus_tag="JXV47_003042"
     CDS             complement(1141..1860)
                     /locus_tag="JXV47_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAX1489006.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEI
                     NKTKKFVEVSVNPDLEYIINGLTAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYY
                     VVRIEEFRSLMDIPEYYQMGNIDQKVLNPALRELKKYFNDLKVTKIKAKKGNKIAKLE
                     FTFSSLTSDLPKISLRNWLEE"
     gene            2513..2608
                     /locus_tag="JXV47_003043"
     CDS             2513..2608
                     /locus_tag="JXV47_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HAX1489007.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(2910..3155)
                     /locus_tag="JXV47_003044"
     CDS             complement(2910..3155)
                     /locus_tag="JXV47_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489008.1"
                     /translation="MRLEKEKMEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLEYKNM
                     TPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
BASE COUNT         1065 a          597 c          499 g         1038 t
ORIGIN      
        1 aaaaaaaatg tcgtttgaaa aactaaataa atttttgatc gtgcattttt aaatttggtt
       61 atcgattaca cgtgcagcac tcccccccga attttaaaga gcataaggaa acgtgtaccc
      121 actttctaaa aaaagtgggt agataggctg tgcctatcac gtttctcaga aaaaaatttg
      181 atatcacttt ttcgccatcg tgggtagctt atgtatagca ttttggcaaa aaacagctat
      241 acaaatatag tatttgtatg gtatacataa attatacata attgcaaaag gagatttttt
      301 atggacattt tagttcggaa tattgatcca aagtttgttg caacaataga caaacgttgc
      361 caagaactca cgaataaaac aggagaaaaa tggagtcgaa ataaatatct aaaagtttta
      421 atcgaaagtg attttgaccg tcaacttacg acttacaaaa aagaccaatt cgatttattg
      481 ctcgataaat ttattgctat ccaaacagaa aatactcaaa tattaagcga gtatgtctac
      541 acaaataatc aaatcattga aatgcttatc ggaggaatga tataaccatg agaaaaactt
      601 ctgtccaaaa acatgttact ttgtacccta gtcatgttga cgttttagat tccatcatcg
      661 aaaaaaatcc agatatcaat aactactcgg aagccattcg ctttttatgt atgagttatg
      721 aacccgatac caacacgacc actaccagca atcaggcaaa actaaatgct atgggaaaag
      781 aaatttccat catgactgaa atcatcgcag aatttgctga tttatatcta aaagatacag
      841 gcgttcttat tggcacaaat tctaaagtat atcaagaagt gaaagaaaaa atcgaagcta
      901 aactaaatcc atcaaatcga aatcgaccaa agaatcatca aaaagaaacc agtcaaacag
      961 tcacttctag aaatttcgac ccaacaaatt ttctaaaacg ataaaaaaca gataggagtt
     1021 attcctatct gttttttatt tagaagcccc atacaatatg ctagaatgta ctagcaatct
     1081 tagtcggttg taagggactt gtctacttgc ttaatgtaag gggggcgagt tcttttttat
     1141 ttattcttct aaccagttac gcagagaaat ctttggcaaa tctgacgtta ggcttgaaaa
     1201 agtaaattct aatttggcga ttttattgcc cttttttgct tttatttttg tgactttaag
     1261 atcattgaag tattttttta gttctcgtaa tgcaggattt aatacttttt gatcaatgtt
     1321 acccatttga tagtattctg ggatatccat taagctccta aactcttcaa tacgaactac
     1381 ataataacca gtagaacggt actgcataag cagtcggaat agagtttttg catacgtaga
     1441 acgcaacgac gtgaaagcag ataattcaaa tctactaaat tcagctgtta aaccattaat
     1501 aatatattct aggtccggat taacactgac ttcaacaaac ttttttgttt tattgatttc
     1561 aaaaccagta aacaaaacaa agtagcgaat agaatcctca tcttcagtac ggtaagtaag
     1621 attaagcata tctttataga gcttttctaa atcaccgaca aaggcttttg tagcagtcat
     1681 cttataatca cttaactctt ttaattcctc gaaagaaaat ctaacttttt tcaaaccacg
     1741 atctttcata cgagcgcata atgcaaaaaa taaatccatc tgcttagcat tgaaattttt
     1801 cagcggtact aaattcaatt cattttgata tttgactgtt aattccgttt tttcatccat
     1861 tcctttcttc cccccttaca aataaataat aacctttaac aaccaactcg taaataggtt
     1921 ggttgttatt atacaaaagg atattagtac tcagataaaa agttgttagt actcagataa
     1981 aaagttgtta gtactcagat aaaaagttgt tagtactcag ataaaaagtt gttagtaccc
     2041 ttctgtatcc gttgggagag taaggctcaa ctgcccccta aaaagggttc taaaaaatct
     2101 ttaaaaaata aataaaataa acgcgcgcgc gcgagcaaaa tttcccgcca aaaaatcacc
     2161 cactttttaa aataaacagg ttcgcgcatg atattaaact gccaatctag ctccctatgg
     2221 tcgctgtaag aaggagtgat cgctacgctc tcacatttta cttgcagcag tcgcctttag
     2281 gctccttcgc caaaaataat tcattaggga ctcctttgtg gcgtcctgag agctcgtcta
     2341 agccgttcta agacaagatt cgataaaaac tatgtccttc gttctaaagc gccttacagg
     2401 cggtcagggc aagccctaac aaccccaagg caataaaaaa cttaggctta tttttgcttt
     2461 tttattgtat aattgattgt cgcctatccg acagtcttgc gactggaagg aggtgtgttt
     2521 cgtgttcact aactttattt gctcccttct tgttgggctt ttaagcgctt tgttcagtta
     2581 ctggttgaat aaccgaaaca agaagtaaaa cttaattaag gcgactcagc ccacaaaaaa
     2641 agccccagag aatccgacct ctctggggct ttcgtgtgtt tcgtgttcac ttatttgcaa
     2701 tcaaattata acagaaataa atatttattt caaaaatatc ctacaaaagt ctaaaatccg
     2761 taattatttc ttatatgcaa catttacaaa taaagtcgct ctgagagctc gtatttttcg
     2821 atttaagacg ttttatttag tttttggtgt atttcattgg tccaagctaa aaaactctta
     2881 gaagcgattt tagagccatt taaacccact taattatatt ctccatgaaa ttcgctccat
     2941 gcgtcaaaag ctgcgtctga aattccgccg tcttcgttca ctagttgcat taatttttcc
     3001 aacgatcgtt ttctttcggg tgtcatattt ttatattcca acaatttttc gtctgttaaa
     3061 tcgaacttga ttgcttgaat tgcttgctct aatttttcta agttttgaaa atattcgtaa
     3121 ggaaattttt ccattttttc tttctccagt ctcacaattt ttctagaaat aaaatcactt
     3181 ctttgccgtc tatactctc
//
LOCUS       DADGKS010000178         3164 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.185, whole genome shotgun sequence.
ACCESSION   DADGKS010000178 DADGKS010000000
VERSION     DADGKS010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3164
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.185"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            311..3070
                     /locus_tag="JXV47_003045"
     CDS             311..3070
                     /locus_tag="JXV47_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489009.1"
                     /translation="MTLDRELEIKRDIVIDFGGFAHNFGTHHIYINEIPQSIEFQNFK
                     GTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYDGSKLGLIYAPR
                     ATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGPYLGKFYGFLDS
                     GDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMFEVSGSGSEFSV
                     NTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGDSSQIHVSSGGQ
                     ISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAVRFENGTQKLTV
                     TNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTVTGEKSNIDIRA
                     DSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDLESPTYFDFQNK
                     RIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPDYFSDMTDLSIN
                     GTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVPTNADKKIYGHV
                     VVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDENEGAGYNPWGEG
                     EQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVDVIPPEPANLST
                     TLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPENQLFAGDVLEIV
                     LNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKIVVEGGLSFLAP
                     SKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQPFTNDAGFSMQ
                     DVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLVLTKENQIAGNY
                     SAEIT"
BASE COUNT         1050 a          572 c          747 g          795 t
ORIGIN      
        1 ttttgccgat gtagagaaaa caaacgaatc aacgcaatca gagaatcaaa gttttgacaa
       61 gactactttt tcagaagaat cgattacttc tgaaactaca gaatctcaaa gtgaggcttc
      121 tactaataaa aggcaagaag aaaataagac aagtgagacc tcagaagtag ctgaacaaac
      181 gtctgatagc agtgaagcgg cactggcaag agctgtttca gcggatgggt acagcgaagc
      241 tgccacaaca gaagaactgg cgcagcttct cgcagacgaa tcagtaacta agatccgact
      301 gattcagcct ttgactttag acagggaatt agagatcaaa cgagatatcg ttattgattt
      361 tggtggattc gctcacaatt tcggcacaca ccatatttat atcaatgaga tacctcagtc
      421 gatcgagttc cagaatttta aaggaacagc tgcacatcca ggtggattga caccaaatat
      481 cgatggaaat gccattatca ttgcttatat gaccgatttt tggggaagca gatatcattt
      541 tacgggagaa ataaaattta ccgggacact tgatttgtat gatgggtcca aattaggact
      601 gatttacgct cctcgtgcaa ctgtcacatt agatggtgtt tccggtgtgt tggatgtcca
      661 accagtgaag gaaggactga atgccgctcc gggtaaagcc tatttttgta gaagctatca
      721 attgaatgtg atcaatggta gtcaacttta tggaccgtat ctagggaaat tctacggttt
      781 tctagattca ggagatgaga ctggtagtgg aaaaacagcg ccaggaatcc atatcttaag
      841 cggttcaaag gtctctcttg attatgatcg ggcagatggc gttagcgatg aaggagaggc
      901 agtcgatacg ctacctggta atgtcatgtt tgaagtcagt ggttcgggaa gcgaattttc
      961 ggtaaataca aagatcaata ttaccaatga caacaatcgc ggaatcatcc aaatgagagg
     1021 ttcaggatcg aaagtcactg tatcgaatgg tgggaaaatc accatcaata cagcaactac
     1081 gggcggattt cgcttgcaag gagattctag tcaaatccat gtatcaagtg gtggacaaat
     1141 ctcggtcaaa atggctggag atgacgatca acccgggaac aatgggatgc gttttgtagg
     1201 aaaaggcctt tctttgatcg tagaaggagc cggatcagtt atcgacatcg ataagcagag
     1261 tgggcgttcc agcgcagttc gttttgagaa tggtacgcaa aagctgacag taaccaatgg
     1321 aggctcattg agggtaagaa atacaggtga tggcaaatct tacgtgaaca gactcaatca
     1381 aggaaatcaa gcgatccaat tttatgacgc ttctggtttt ctagaaagtc caggttcagc
     1441 tgattttaca gtcactggag aaaaatcaaa tatcgatata cgcgcagatt ccggagcaac
     1501 tgtagataca actggagata ttgatttaaa ttttacggca ggtgaaaaaa cttatttagt
     1561 catggtcggg aaaacagggg aagataagac cggcatcatc agtggggatg tgttgaatgt
     1621 ggacttagaa tctcctacct attttgattt ccaaaacaaa cggattggaa gcgagaccaa
     1681 tggcataggc ggctgggtat tccaaggaaa tggagattct tctttaaaga tcgcccattc
     1741 agaaatcgct ttatggcgaa aaacaggcgc aacattcgat aactttgaaa aagacccgga
     1801 ttatttttct gatatgacag acttatcgat caatgggacc gacttaggca atttcgtatc
     1861 aagccctagt gcaggtttaa caaatgaatt tgctcagaca ggtgccggaa tgaaaaatta
     1921 taatcgaatc agtgccaata atcagctccc gatgattgaa tccttaagag tgccaacgaa
     1981 tgcagataaa aaaatctatg ggcatgtcgt tgttcccgaa ggtgtcgagg caaagccaag
     2041 agatgcttgg acaggcgaag tagaagtgac tttacgtatt acttacgcag atacgacgaa
     2101 atcatctgta gaaattactg ctctcacgca aggacaaaca gatgaaaatg aaggggcagg
     2161 atataaccca tggggagaag gcgaacaagg cggcttgttc gaagttcaag tacccaatga
     2221 tgagagatta aaaacggagg atcaagtgca agttgttgct gctaaaaaag taagaggtgg
     2281 ccaagaagtg acagaactgg actctgccaa aacgacagtc gatgtgattc ctcctgaacc
     2341 tgctaattta agtaccacat tgatcaatgc agcttctcgc acgatcacag gtacaggtga
     2401 agcaggagcc ttggtttcat tgaaaaaaaa tcaagctgtt ttgtcagaaa caactattga
     2461 tgatacaggg gaatttgttc tttctatccc agaaaatcaa ctttttgcag gagatgtatt
     2521 agaaattgta ttaaacgacc aagcaggaga agctactgct aagggtgtgc agaacaagcc
     2581 aagtaccaac gatgaaattg ggaatcacaa tccaagtgat acgccagttg tttatcatga
     2641 tgccccgcct tttgcacctg ctacgaagat cgtagtagaa ggtggtctct catttcttgc
     2701 cccttccaaa ctcgattttg gtcagatcaa agcaactggt ttgacacaag aagcatttgg
     2761 ccaaatggat atacaggaaa aattatggat ttatgatcag cgagaaacga aaaatccgtg
     2821 gatcttaacg ataaaattat ctcagccttt cacaaatgat gcaggatttt ctatgcagga
     2881 tgtcctatat ttcaagaaag gagaggagta tcaattagtg aatgaagaag aactggaaat
     2941 tgtcagagga caaaattcaa cgaatgtgca agcagattat tcagaatatt taaataacgg
     3001 tcgggcgttt aaacttgtct taaccaaaga aaatcagata gctggtaatt actcagcaga
     3061 gataacatag acattagcag atgcgccgac agaataaaga tcaaggagga tgattgatga
     3121 atcgaatatg gaataaaagt catcgaaaca actgctcttt actt
//
LOCUS       DADGKS010000179         3087 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.186, whole genome shotgun sequence.
ACCESSION   DADGKS010000179 DADGKS010000000
VERSION     DADGKS010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3087
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.186"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..313)
                     /locus_tag="JXV47_003046"
     CDS             complement(<1..313)
                     /locus_tag="JXV47_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HAX1489010.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GY"
     gene            complement(331..1755)
                     /locus_tag="JXV47_003047"
     CDS             complement(331..1755)
                     /locus_tag="JXV47_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAX1489011.1"
                     /translation="MKELFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSG
                     KSTLLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQNPRGQFFTTN
                     TTSELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLS
                     LNSKLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVK
                     NRTVKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDIN
                     FDVKVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQF
                     FTESVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSK
                     TNLFLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGG
                     IKKDIKLRVEDSTLIEQIFNDITK"
     gene            complement(1757..2425)
                     /locus_tag="JXV47_003048"
     CDS             complement(1757..2425)
                     /locus_tag="JXV47_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAX1489012.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFGTSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(2556..3074)
                     /locus_tag="JXV47_003049"
     CDS             complement(2556..3074)
                     /locus_tag="JXV47_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAX1489013.1"
                     /translation="MTAGVTTGAFYKHFTSKEALFEEIIQPHINALINMYNEEFTKYL
                     LNLENIDIEKSWRENFNELDPFINYIFENKRIFDLVLFQSAGTKYQDIVEKITSFVTK
                     KTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYATFYDILKHSYSKEKTMLLTRRLY
                     QFSVPGWIELLS"
BASE COUNT         1084 a          533 c          387 g         1083 t
ORIGIN      
        1 catatccaaa tacagataga ataatatcag ctaagatcgc catactaatc gaactgataa
       61 accaaggtaa gtacgccccg cccattaacg taaaaaataa caataaaaca attgtgtaaa
      121 tagtaaaaat tccttttcta gggtagttat agctaatata aacaaatatg attccagata
      181 ataatccaaa aatccctggg gatatgctgt gaccaaacgc cccaccaata ctactaacca
      241 ttattgaaaa aaagtaaatt actagggaaa taactgtagc taaaccaata aaaatataat
      301 cttttgtttt catatatatt ctcctcaatt ctatttcgtt atgtcattaa aaatctgttc
      361 tatcaaagtt gaatcttcta ctctaagttt tatatctttt tttattccac cattttttaa
      421 ataaataatt ctattgcatg ttttataaag aaattccgga tcatgagtgg ctataactac
      481 tgcacccttt tcttttaagt ctttaataag gtcagcaatc ctttccatat tgatataatc
      541 caacccactt gtaggttcat caaatagaaa taaattagtt tttgacaatg aagctataga
      601 aaccaataat ctttgttttt ctccaccgga taaatcaaac ggtaattgat ctttcatttt
      661 ataaagttcc atttttttta aaattttttc ttgctgatct ttactaacta tttcattccc
      721 cagggctaac tcgctcctca ctgattctgt gaaaaattgg taatccattt cttgcattac
      781 taaaaacggc gatgacaaat tttttttatt ttcgattatc tttcctttgg tagggcgaat
      841 aatcttcatg agtattctta gtaaggttgt tttccccaca ccgtttttcc ctaccaaacc
      901 aataacatct ccaactttga catcaaaatt tatgtctttt agaatatttt cataagtaat
      961 ttcttcaact tttaatacat ctgcacttac cttttcgata tagggaactt caatcgaact
     1021 attaaaaatg tcaaatttcc ttaatgcgtt attgttttca gtttttaaca actgaatagt
     1081 tgtagttttt acagttctat ttttaacaaa tagaacttga tcaattaatt ctttcaaata
     1141 gtaaaaacga tgttcagcta taacaatagt aaatccttta ttttttaaat cacaaagtaa
     1201 gtcagcaagt ttcttagtcg ctttgaagtc caaatttgaa gacggttcat ccaatataat
     1261 taatttagag tttagcgata aactacatcc aatagaaatt ttctgccgtt caccacttga
     1321 tagcgaaaaa atgtttttat ctaatatatt tgaaagatct aataattcag ctaattcatt
     1381 gattctttta tccatatgct cttttgtaaa tccaaagttt tccatcgaaa atactaactc
     1441 actcgttgta tttgttgtaa agaattgtcc tctaggattt tgacttacgt agccaatatt
     1501 ttttgatata ctttcttgtg ttaaggattg tagcgagtta ttttcaaata aaatttcccc
     1561 aaccaatttt ccgtcataaa gtcttggaat aagtccattc attaacttta atagtgtgga
     1621 tttcccactc ccagaagaac cagtaatcaa tgtaagactg ccttttttta ttgaaaaatt
     1681 aaggtcaaca agcgcttgtt ccttaacatc cttatatgaa aaagaaacat tgttaaattc
     1741 aaacaattct ttcacctcaa atcaaaatac ttaagaaaaa aatagtaacg gaaaacagga
     1801 tgatatagtc taataagctc atgtttgttt tatagtaaga acttcttttc acaggagatt
     1861 ctatcccctt tgttattgca ttagcggtca tttcttcagc aatcatagtt gcacgtataa
     1921 gaacgggaac taacagaaat tccaaatatt gcagaggctg aaaaaaagac aagcgaatgt
     1981 ttctcatttt taaagattct ttaatcattc ttatttcaga acgataagtc ggaaagaatc
     2041 tgatcactac tgtaatactt aacattattt ttttcggtaa atgtattttt tctaaagagg
     2101 ataataattc attgctagta tagacactaa ccaacaacca tgagatcatt acgaccggca
     2161 acattcgaaa tacaatatat aaggatgtcc caaaaaatat agtaaaaaac tctatcttga
     2221 tagcatcaat aattttcatt actaaaaaca gaactgaata aatcaagatg aaataaatac
     2281 atgtctttat tttacgaaac atcaatacta aaactgtagc aataatgaaa caccccactt
     2341 gaaatatatt tccctttcct aaaaaaataa tgaccggaaa aaaaatattt aaagtaatca
     2401 aggttaacgg attgattttt gacactcttt cacctccaaa aaataagatc gcactgttat
     2461 cttaagctga caaaaatgca ccgttattca gataacagtg cgatcttatc aaaaagcata
     2521 actgagaaca attctcaatg caagcttttt tttaattaac tcagtaattc aatccaccca
     2581 ggaacagaaa attgatacaa tcttctggtt aatagcatag tcttttcttt tgaatagcta
     2641 tgcttcaata tatcatagaa tgtagcgtag aatgagtaaa tgtagaagtg gatttcttct
     2701 tcattaaaga ctaaattttg attgatcatt ccgatagtct ttaacttatc tagacaacag
     2761 actgtctttt ttgtcacaaa tgatgtaatt ttttcaacaa tatcttgata tttggttcca
     2821 gctgattgga ataaaaccaa atcgaatata cgtttattct caaaaatata attaataaat
     2881 ggatctaatt cattgaagtt ctctctccaa cttttctcta tatctatatt ttctaagttt
     2941 aagaggtatt tggtaaactc ttcattatac atattaataa gcgcattaat atgcggctga
     3001 ataatttctt caaataacgc ttccttagaa gtaaaatgtt tataaaaagc acccgtagtt
     3061 acgcctgcgg tcaagcacag ttgcctt
//
LOCUS       DADGKS010000180         2955 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.187, whole genome shotgun sequence.
ACCESSION   DADGKS010000180 DADGKS010000000
VERSION     DADGKS010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2955
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.187"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            90..407
                     /locus_tag="JXV47_003050"
     CDS             90..407
                     /locus_tag="JXV47_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HAX1489014.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(498..863)
                     /locus_tag="JXV47_003051"
     CDS             complement(498..863)
                     /locus_tag="JXV47_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489015.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1071..1553
                     /locus_tag="JXV47_003052"
     CDS             1071..1553
                     /locus_tag="JXV47_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489016.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSTFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1750..2640
                     /gene="pstS"
                     /locus_tag="JXV47_003053"
     CDS             1750..2640
                     /gene="pstS"
                     /locus_tag="JXV47_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HAX1489017.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT         1009 a          460 c          566 g          920 t
ORIGIN      
        1 tttttaaaac atcacaagga aaaacttaac tatggtatta tctaaacata attttttcgg
       61 tatttaatat ttaattagga ggtaatattt tgctttttta tagtaatttt atcttaatag
      121 tagcgatatt attacttctg aatatatgga tttttgatag gagtagaaat tcaagtatag
      181 gttttagaac taaacgaagt ttgtcttcta aaaaaaattg ggtatactca caaactattt
      241 tttatggagg aattgtttta attagtttac tttcttcaac actttattct ttgaatatta
      301 tagatgtttc cacctcaaat tcaatatcta ttattggaat cattattgct gcaattatta
      361 cacaactgtt tttagtgttt ggagagaaga aaagaagtaa aaaatagaaa aactagtgat
      421 agttttggtg atataagaaa aacatatatg tataaaaaga agaaagtagc ttctctttgt
      481 acatatatgg tttgttttta tggatgccga gcttttttat aagataaggc taccgcccat
      541 aacgacccaa ggatttgtgg aactaagtaa atacctgcaa gaagcaagat cagctgggtc
      601 ggttttaaag gatgatagaa gtaacgccat tcagtaaaat tggcgcaaaa taaataggaa
      661 gtgacagtag atataatatt ggcaatgaat aaagatataa tacgcctgtt cctttgaaaa
      721 taatatccag caaaaagaga taaaaatatc aatgtgatga acccgcttac ggaatgataa
      781 cgaaaatcaa gcagtaaggc gaaatgcaca taaggaacaa aagataaaag caacggaagg
      841 tttttccagc aagtttttat catctttcat caccacctaa caagtgttat tattttgtta
      901 gttttattgt aaattgaatc ctgcaataat caattacttt ttcattattt ctagattaaa
      961 tgaataaact ctcatgccat tatctctaaa aaaaaagttt ttccccctaa tttttttaga
     1021 tagaaaattg tatagtatga tgagagaaaa agtagtttgg gggaacgtta atgagaagaa
     1081 aagcagtaat cgatcggctt tatttatttt tttggttttt tcctatcgtt ttgctacctt
     1141 ttacatgggt aaatgctgtt gtacaaggtg cggagatatt aggcctgatc caaggaagcg
     1201 gatttgtggt ttctaggaat tttccagctt tgattgtttt ctatttagtg ataagtgtag
     1261 gtctcttatt accaaaatct ctgatcaatc actacaattg gcagctgctt tacttttctt
     1321 gcttattagt atttacatct acgttttctt tgctgcctcg cttgattatc ggccctaatg
     1381 gtttgagcga gagtggattg aaggatttag cttattcctc catgtatttc ttgacgatca
     1441 aaccatggtt ctatttagta attgcctcat ttattcttgc aacatttttt tacttctgga
     1501 cagaaatcag gataaaaagt gaacgatctg tatctataaa aaataactat tgatggtgga
     1561 tcatcagtaa aaaaacatat gagctgcgta aaatgcatgt ttctcatatg ctttttttat
     1621 tattatgtaa agaatgcgaa aaacgtttac atgattttta cataacttaa ctatattttt
     1681 acagcaacca tacgagggat ttacagtcga ctgataaact ttagttgtaa ataagaaagg
     1741 agcaataaaa tgaaaaaagt attgtttact ctaggtatga tgggaattct tttagccgga
     1801 tgcggctcag gatcaggaaa tacagatggc tctgccacac aaaataattc aagtgactca
     1861 aatgaacaag taaaaatcgt tgcggtaggt tcgacagcat tacagccgtt agtcgatgca
     1921 gcacaagaaa gctttgtaca agaaaatcca aattatcaaa tctctgtaca aggaggagga
     1981 agcggaactg gtttgagcca agtcgaagct ggagcagtta ctatcggaaa ctctgatgta
     2041 tttgcagaag aaagagacgg agttgatgct tcaaaattag tggatcataa agtagcagtg
     2101 gtcgggatgg caccaatcgt caataaagat acagatgtca aagatatcac caaacaggaa
     2161 ttgattgata tctttacagg aaaaatcact aactggaagg aagttggcgg gaaagatcaa
     2221 aaaatcaacg tcgtgaaccg tgcaaacggc agcggtaccc gcgcgacatt cgaaaaatgg
     2281 ggactggatg gtgctacccc tgtgcagtcc caagaacaag attcatcagg aacagttcgg
     2341 cagctggtaa gtcaaacacc aggagcaatc agctatttag ctttctcata tctcgatgat
     2401 tccacacaag cactaagtat cgacggtgta gaaccaaaag aagagaatgt agcagataac
     2461 agctggggaa tctggtcata tgaacatatg tacacgaacg gaaaaccttc ccctgaagtc
     2521 caaaaattct tagactacat gatgacagaa gaaatccaag aaggacctgt caaagaattg
     2581 ggctatttac caatcacaat gatggaagta gaacgtgatc acgaaggaaa tatcaaataa
     2641 ctagcagata aacatgccac ggtagtcgtt actattaagg aaaaatcaac tatgtttccc
     2701 cacatataca tttttccttt aattgtgaaa aatagttcct catattttgc cgttttttga
     2761 gctaataccg agggtcagct gattgaacac cgtttattcg aaaaaaagag ctacgacata
     2821 gaactgtcgt aacttttttt ggctcttcgt caaatcgtgt tggtgaagac aaatttgaat
     2881 aaaacttaga ccgatatgcg gcgcgttctg tgcgccgcat atttttttag ttttcaaaga
     2941 tcagaccttg ttgta
//
LOCUS       DADGKS010000181         2944 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.188, whole genome shotgun sequence.
ACCESSION   DADGKS010000181 DADGKS010000000
VERSION     DADGKS010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2944
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.188"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..1419)
                     /locus_tag="JXV47_003054"
     CDS             complement(<1..1419)
                     /locus_tag="JXV47_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002831727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1489018.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMA"
     gene            complement(1416..2288)
                     /locus_tag="JXV47_003055"
     CDS             complement(1416..2288)
                     /locus_tag="JXV47_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAX1489019.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(2630..>2944)
                     /locus_tag="JXV47_003056"
     CDS             complement(2630..>2944)
                     /locus_tag="JXV47_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAX1489020.1"
                     /translation="KTVPLIISRQTSVDSQLAEWLGFSIDQLSIVGTYNLLYNASLMV
                     DNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSPAARKFLDVLTEK
                     YS"
BASE COUNT          887 a          609 c          560 g          888 t
ORIGIN      
        1 tgccatctca tctgcaacga attgtacttc tgtacctacg atgacttgcg cattttttcc
       61 gtcgatgatc ttcataccag gtacgccagt ggctttgatt ttattttgat cgatcaggcc
      121 tgtatctttg acttgcaaac gaaggcgtgt agtacagtta tcgatcgaag ttacattgtc
      181 ggctccgcct aatgcagcgt agattttgct tgcttgtgcc gcatatttat tgtctgaatt
      241 agtcgttgca gtatcgtcat ctgaaagatc tgcttcctcg cggccaggag tcatcagatg
      301 gaattttttg atagcaaagt taaagccaaa gtagtaaatc actgctgtta ctaatccttg
      361 gacgatcaac atcaatggct gattcgcaat cggatttttc aaagatagga agtaatcgac
      421 aaatccggca ctaaaggcaa atcctgctgt ccaatggaag aatgcactca ctgctaaaga
      481 aatcccagtg aaaattgcat gcaagacata taatggccaa gcaacgaaca taaatgagaa
      541 ttcaagtggt tctgttacac cagtaaagaa tgaagcaaaa gctgctgcta acatcaagga
      601 agctgttttt gctttgtttt ctggacgtgc atttctgtaa atagcatatg ctcctgctgg
      661 aagcccgaac atcatgattg ggaaaaatcc agcttgatac attcctgtta cgccttttgt
      721 tccttcagaa gccaaaaatt taccaatatc attgattcct gctacgtcaa accagaacac
      781 ggagttcatt gcttgatgca atcctgtagg gatcagtaaa cggttgaaga agccataaag
      841 acctgcacca ccccagccta aactcaaaat gaatttagca aaagaaacta aagcagagta
      901 aaccggaggc catacgagca gtagcactgc actgatcagc aacatgacaa aggcagccaa
      961 gattggcact agacgcttgc cgctaaagaa agataaagcc atcggtaatt ttgcttcgtg
     1021 gaaacgatta taaagagctg ccgcaatcaa tccggcaata ataccaataa atacgttact
     1081 gatctgagca aaagatggat caactgattc tggtttgata ttcaataaag tagctactga
     1141 atcagttttt aaaacattta ctggaacttc aaatgcgacc aaacctgcca aggcagcagc
     1201 acctgatttg tccactgaca tccctagtgc taacccaacg gcaaacagca aaggtaattg
     1261 acctaaaact gcgttaccgc cagcttgtaa aaaatgagcg acaatgtcgt tactataaga
     1321 tgcccaccag tttccgatcc ctactagtaa agcagcagca ggtaagaccg caactggaag
     1381 ttgaagggaa cgtcccattc gttgtagata tgctttcaat ttttttcctc ctcatgattg
     1441 ttaacatttg tttgtacgat tgcgcttctt aaacgctcga tatggatggc caagtaaccc
     1501 agttcttctt tcgtgatcgc gagctggtat tctttggtca gcaacacacg gattttttta
     1561 gaaatcttat agctttctgg gtattttcgt ttgaccattt ctacgatttc cgtgtctaaa
     1621 acagcatatt gttgcgcatg ggttcgttgt agaagcagtc gtaaatgatt caccagtctt
     1681 gaataattca gtgaaaatgg ttctgaatgg atatctgttt ccaattctga ttccactaaa
     1741 tggatgatgt cagatacaat cgtcacttca cggatactgc gatggttatt gttccgaccg
     1801 cttcgtccgc tgtgaatatg gattgcgata tatcctgctt cgtcataagt atatggaatc
     1861 ccaagctctt ttgtcagata ctctactgcc cattgagcaa tactgaattc atcactgtaa
     1921 agcacttcga tttctcttaa aagtttgttg cggatgacga taccgttatt aatgttctcc
     1981 gcagaaaaag caatgtggtc ggtcaaagcg atcaatacat gttcattcaa cttttccatc
     2041 aaaacagttt ccgcatgatc aatgatcgtt tctgctgcaa ataaaaagcg ttcatcaatc
     2101 tgattaagta aattttgcaa cttgatttga ccttctggtt ccatgacaaa tatccgttcg
     2161 acatcacgat caaaaatcaa atcatttctt tttctgtcaa atccaatccc ttttccaata
     2221 gctacttttt cctgtccacc gtcatctacc aatactgcat tttgattaaa gatctttttg
     2281 attttcatgc gcgcaccctt tttgaagatt tggttttcac gtttgctaga ccagttgatt
     2341 gcggccaaac aaaaatagac acgaaaaacc tcctagggaa accatgttcc tcagagattt
     2401 ttcatgccta gtatgatcta gtcacatgaa acgaattatt gttaacgtaa tcaattttat
     2461 atagacagtt atgttttgtc aattcttttt ttataattat agtaatttac tggaattatc
     2521 agaaataaaa ggaaggaaca aattaagaaa cttatgttat ttaatcattg gatcttttgc
     2581 ttaacttatt cgttgttaaa aagctgaaag cgaaggaaaa aaactctact taactgtatt
     2641 tctccgttag gacatctaaa aatttacgag cagcaggaga aagaggctgg tcttttttcc
     2701 aaatgagatt cagtgaagct tgtaatggcg gatcgagtgg gatgaatact ttttccgtcc
     2761 cataagtatt gatgatccca tctagagcta atgcaccaaa agtcccgtta tcgaccatca
     2821 aagaagcatt gtacaataag ttatatgttc cgacgatcga taactgatct atgctgaaac
     2881 ctagccattc agctagttga ctgtccactg acgtttgccg ggaaatgatc aaaggaacag
     2941 tttt
//
LOCUS       DADGKS010000182         2936 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.189, whole genome shotgun sequence.
ACCESSION   DADGKS010000182 DADGKS010000000
VERSION     DADGKS010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2936
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.189"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..227
                     /locus_tag="JXV47_003057"
     CDS             <1..227
                     /locus_tag="JXV47_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAX1489021.1"
                     /translation="FIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYL
                     SKKLVEGMGGEMTARLDGGIFSISVKLRRV"
     gene            422..2071
                     /locus_tag="JXV47_003058"
     CDS             422..2071
                     /locus_tag="JXV47_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAX1489022.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            2665..>2936
                     /locus_tag="JXV47_003059"
     CDS             2665..>2936
                     /locus_tag="JXV47_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAX1489023.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNP"
BASE COUNT          963 a          491 c          631 g          851 t
ORIGIN      
        1 cattcattcg attaacagtg gccaatccta tcaaaccagg agcgcaaacc tctgttgaaa
       61 aagtcttcca gcgtttttat accgaaaata ccagccgcac aaatacggaa tctagcggaa
      121 tcgggcttta cctgtcaaaa aaattggtgg aaggaatggg aggagagatg accgctagat
      181 tagacggggg catcttctcc atctccgtca agttgcggag ggtttaattg gctctaattt
      241 acctgaagtg aatgacaaaa aattgtatct cgttttaaag acatcttctt ttttggaagg
      301 tgtttttatt ttggtgtgat tgatacgaat taggtaacga agacagttat ttttgtaccc
      361 ccttttcaaa tagcgcaaca gtgctatact aaaactaaca aatcaaggaa cggagaggga
      421 tatgggccaa agagaattta tcgttttaat tattattgca gttgttattt tattagttgt
      481 tttagacatt ttttcacgtt tgaaagtaaa ggaaacagtt cgtagtaatt ggggaaaaat
      541 tccttatcaa ccgagatttg ataaagaaga aagtttgaag gatgcgtggc tcacggagaa
      601 aaaattccgt tcatgggata gtgaaatcga cgatcttact tggtatgact tggatatgtt
      661 cgaagtattt gaagggatca acagtaccta ttctagtgta ggttcagaag cgttgtatca
      721 gcgtttacgt agctttgatt ttggagaaga ttatcagtta gaaaaactaa ttgcttttta
      781 tcaggaaaat cctcaactga gagaaagaat ccaatatcaa ttcgctcgtt taggaaaaaa
      841 agatcataat tttgcaaaac aatatctagc ggatggaaaa agtaaaaaga ttggacgcgt
      901 aggtttattt atttttcttg gcttgcttcc gctggtgggt gtaggtttgc ttcttttagg
      961 gcaagtacta ggaatctatc tagcaatcgg tggcttagta ttcaatacgg tctattatct
     1021 agtgaagaaa caaacactag aaacagagct gaatagcatg agttatttgg tttcaacgat
     1081 ttcagccgcc aatcagttag caaaaatgac gacaccactt caaaaagagc tgaaacagca
     1141 aactaaacca ttaagagaca tccctaaatt aggtttttca tttcgaatga agagcgggag
     1201 tgaagcagaa ttgatttttg aatatgtcaa catcatgttc atgctgccat ttatctccta
     1261 tcatttcgtt ctcactaaat tagaaaagca ttcaactgaa gccatcaagc tgtgggaatt
     1321 gctgggagaa ttggaagttg cagcagccgt tttgaattat cgcacctata tgccgatcac
     1381 ttgccgacca gagtttactg agggcggtgt gacagcgaaa gatatctatc atccattgtt
     1441 aaaagaagcg gtagttaatc cagtcaactg gcagaagaat acattagtca cgggttccaa
     1501 tgcatcagga aaatctacgt atgtcaaaag tatagccatc agctgtattc tagcacagac
     1561 gatccaaaca gcgattgcag aacagtttac cctgcaacct ggacatgtgt tgacttccat
     1621 ggcaatcgaa gatgatttat ttgaaggcga cagttatttt gtttcagaaa tcaaatcgat
     1681 caaacgtttg ctggaccaag tggcttccaa agaacgctgc tactgcttcg tagatgagat
     1741 tttaaaagga acaaatacga tcgaacggat tgcttcttcc gcttcagtcg ttcggtggct
     1801 tgcggagtat ccatctttag catttgtcgc cacacatgat atcgaattga cagagatttt
     1861 aaagaattat tgtgagaatg tccactttga agaacaagta acagaaggaa aaggaatcag
     1921 ttttgatttc aaattaaaag aaggaccttc aaggacccga aatgcgattg ccttgctgaa
     1981 agttttgaat tatcctaaat ccatagttga acaggcccaa aaagaaagtt tgttgttcga
     2041 tgaacagcgt cagtggtatc cgtttgatta actttatcaa acgaagcatg atgcgtgggt
     2101 ccaaaaagac gattatcaaa agaagtacat tgatgccaaa aaagtggcag aattcaatgg
     2161 gaacgagtct gctgtccaga tgatcttgga agatttagca aaagacgata caaaataaac
     2221 cacgctgtct tccttctagc agcttttatc gaaaaaactt agcatcagcg acgagacgca
     2281 cgttccatgg caaagttctc cgtaaaacaa acagcgaaaa cagaaattga aaataactat
     2341 ttccatttta tttatttcgg ttaaaataaa agaaaaaagc tttcgataaa aggacggagg
     2401 aaagcttaac atgaataaaa aagacaagaa cctcagttat aaggatcttc tatatgtcat
     2461 cgtagtagtt gctgtcggta cttttatgat tttaaaagtt ccagagttgt ttagatagtt
     2521 attctatcga agatgatcat gaactagaaa acacatctcc tctttgttag caggtgtgtt
     2581 tttgtgtgga agccaagttg ttttttcatc tgctgtattc catgatacaa ttaagaatca
     2641 tgtctataag gagataggaa ataaatggca aatgcgcttg aaataaataa tttgaaaaag
     2701 atctatggaa gtggggtcga agcattgcgg ggaatcgatc tttcggtgaa agaaggagat
     2761 ttctatgcgc tattagggcc aaatggagct gggaagtcta caacgatcgg gattattact
     2821 tctttagtca ataaaacatc tggaaaagtg aatgtcttcg gttatgatct ggacaaggat
     2881 ctagttcgag caaagcaaca gattggattg gttccacaag agttcaattt taaccc
//
LOCUS       DADGKS010000183         2917 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.190, whole genome shotgun sequence.
ACCESSION   DADGKS010000183 DADGKS010000000
VERSION     DADGKS010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2917
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.190"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..132
                     /locus_tag="JXV47_003060"
     CDS             <1..132
                     /locus_tag="JXV47_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAX1489024.1"
                     /translation="LTCEQLVVSLADEEELTTNVDGDEGDKLPVTIKVLPSHLQVYC"
     gene            354..>2917
                     /locus_tag="JXV47_003061"
     CDS             354..>2917
                     /locus_tag="JXV47_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489025.1"
                     /translation="MNQYVKKLIASILFVFPLLMVTSVFADVEKTSESTQSENQSFDK
                     TTFSEESITSETTESQSEAPTSNTRQEENKTSETSEVAEQTSDSSEEVQVRVVSADGY
                     SEAATTEELTQLLADESVAKIRLTQPLTLDRELEIKRDIVIDFGGLAHNFGTHHIYIN
                     ETPQSIEFQNFKGTAAHPGGLIPNIDGNAIIIAYMSDFWGNRYHFTGEIKFTGTLDLY
                     DGSKLGLIYAPRATVTLDGVSGVLDVQPVKEGMNAAPGKAYFCRSYQLNVINGSQLYG
                     PYLGKFYGFLDSGDETGSGKTAPGLHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVT
                     FKVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSRVAVSNDGKITINTATTGGFRLQG
                     DSSQIHVSSGGQISVKMAGDGDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSA
                     VRFENGTQKLTVTNGGSLKVRNAGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFT
                     VTGEKSNIDIRADSGATVDTTGDIDLNFMAGEKTYLVMVGKTGEDKTGIISGDVLNVD
                     LESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKAGVTFDNFEKDP
                     DYFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRV
                     PTNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSPVEITALTQGQTDE
                     NEGTGYNPWGEGEQGGLFEVQVPNEERLTTGDQVQIVAAKKVRGGQEVTELDSAKTTV
                     DVIPPEPAKLSTTLINAASRSITGTGEAGALVSLKKNQAVLSETTIDDTGKFVLSIP"
BASE COUNT          952 a          512 c          691 g          762 t
ORIGIN      
        1 cttacttgtg agcaattagt tgtgtcatta gctgatgagg aagaattgac gacgaatgtt
       61 gatggagatg aaggggataa attacctgtg acaatcaaag tgttaccctc acatttacag
      121 gtttattgtt aaaatggagg ttgtgaccga agagttgtca ggaggacatc ggttgttcgg
      181 aataagggac tgtgacaaga cttttgtcac agcctttttt tgtacaaaaa agaaattttc
      241 acctaacaga aaaatttgcc ataaaaatac atattttaaa tatgaaagta caattacaaa
      301 taaattaaaa cgttaaaata aaattgtcaa aacgtcagag aggatggtgg agaatgaatc
      361 aatatgtaaa aaagctgatt gcgtcgattt tgtttgtctt ccctctcttg atggtgacat
      421 ccgtttttgc cgatgtagag aaaacaagcg aatcaacgca atcagagaat caaagttttg
      481 acaagactac tttttcagaa gaatcaatta cttctgaaac tacagaatcc caaagtgagg
      541 cgcctacttc taatacaagg caagaagaaa ataagacaag tgagacctca gaagtagctg
      601 aacaaacgtc tgatagcagt gaagaggtac aggttagagt tgtttcagcg gatgggtaca
      661 gcgaagctgc cacaacagaa gaactgacgc agcttctcgc agacgaatca gtagctaaga
      721 ttcgtttaac tcagcctttg actttagaca gggaattgga gatcaagcga gatatcgtta
      781 tcgattttgg cggacttgct cataatttcg gcacacatca catctatatc aatgagacac
      841 ctcagtcgat cgagtttcag aattttaaag gaacggcagc tcatccaggt gggttgatac
      901 caaatatcga tggaaatgcc attatcattg cttatatgtc cgatttttgg ggaaacagat
      961 atcattttac gggagaaata aaatttaccg ggacacttga cttatatgat ggttctaaat
     1021 taggcctgat ttacgcccct cgtgcaactg tcacattaga tggtgtttcc ggtgtattgg
     1081 atgtccaacc agtgaaagaa gggatgaatg ccgctccggg taaagcttat ttttgtagaa
     1141 gctatcagct aaatgtaatc aatggtagtc agctttatgg accatatcta ggaaaattct
     1201 atggttttct agattcaggt gatgagacgg gcagtggaaa aacagcacca ggactccata
     1261 tcttgagtgg ttcaaaggtc tctcttgact atgatcgggc agatggcgtc agcgatgaag
     1321 gagaggctgt cgatacgcta cccgggaatg tcacatttaa agtcagtggc tcaggaagtg
     1381 aattttcggt aaatacaaag atcaatatta ccaacgacaa caatcgcgga attatccaaa
     1441 tgagaggctc aggatcaaga gtcgctgtgt cgaatgatgg gaaaatcaca atcaatacag
     1501 cgactactgg cggatttcgc ctgcaaggag attctagtca aatccatgta tcaagtggtg
     1561 gacaaatctc ggtcaaaatg gctggagatg gcgaccaacc tggaaacaat gggatgcgtt
     1621 ttgtagggaa aggactttct ttgatcgtag aaggagccgg atcagtcatc gatattgata
     1681 agcaaagtgg tcgttctagc gcagttcgtt ttgagaacgg tacgcaaaaa ctaacagtaa
     1741 ctaatggagg ctcattgaag gtaagaaatg caggggatgg caaatcttat gtgaacagac
     1801 tcaatcaagg aaaccaagcg atccaatttt atgacgcttc tggttttcta gaaagtccag
     1861 ggtcagctga ttttacggtt actggagaaa aatcaaatat cgatatacgc gcagattccg
     1921 gagctaccgt agatacaact ggagatattg atttgaactt tatggctggc gaaaaaactt
     1981 atttagtcat ggtcgggaaa actggggaag ataagactgg catcatcagt ggggatgtgt
     2041 tgaatgtaga cttagaatct cctacctatt tcgatttcca aaacaaacgg atcggaagcg
     2101 agactaatgg cataggtggc tgggtatttc aaggaaatgg cgattcttct ttgaagatcg
     2161 ctcattcaga aattgcttta tggcgaaagg caggagtaac gttcgataac tttgaaaaag
     2221 atccggatta tttttctgat atgacagact tatcgatcaa tggaaccgac ttaggtaatt
     2281 ttgtatcaag ccctagtgca ggtttaacaa atgaatttgc tcagacaggt gccggaatga
     2341 aaaattataa tcgaatcagt gccaataacc agcttccgat gattgaatcc ttaagagtac
     2401 caacgaatgc agataaaaaa atctatgggc atgtcgttgt tcccgaaggt gtcgaggcaa
     2461 agccaagaga tgcttggaca ggcgaagtag aagtgacttt acgtattact tatgcagata
     2521 cgacgaaatc acctgtagaa attactgctc tcacacaagg acaaacagat gaaaatgaag
     2581 ggacaggata taatccgtgg ggagaaggcg aacaaggcgg tttgtttgag gttcaagtac
     2641 ccaacgaaga aagactaaca acgggggatc aagtgcaaat agttgctgct aaaaaagtaa
     2701 gaggcggcca agaagtgaca gaactggact ctgccaaaac gacagtcgat gtgattcctc
     2761 ctgagcctgc taaattaagt accacattga tcaatgcagc ttctcgctca atcacaggta
     2821 caggcgaagc aggagctttg gtttcattga aaaaaaatca agctgttttg tccgaaacaa
     2881 ctattgatga tacaggtaaa tttgttcttt ctatccc
//
LOCUS       DADGKS010000184         2887 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.191, whole genome shotgun sequence.
ACCESSION   DADGKS010000184 DADGKS010000000
VERSION     DADGKS010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2887
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.191"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..695
                     /locus_tag="JXV47_003062"
     CDS             <1..695
                     /locus_tag="JXV47_003062"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HAX1489026.1"
                     /translation="DAKLAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSL
                     LLHPDKRFDELPQYTIIAASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVS
                     DMESGRISHIIIGIGLNFSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELF
                     TYLSHPEKALDFYKEKSFVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLS
                     SGEISLTSIRTQ"
     gene            complement(1012..1536)
                     /locus_tag="JXV47_003063"
     CDS             complement(1012..1536)
                     /locus_tag="JXV47_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinB family protein"
                     /protein_id="HAX1489027.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            1823..>2887
                     /gene="scm"
                     /locus_tag="JXV47_003064"
     CDS             1823..>2887
                     /gene="scm"
                     /locus_tag="JXV47_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAX1489028.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT          934 a          581 c          528 g          844 t
ORIGIN      
        1 aagatgccaa actggcagca gctcaaggag attctgtttc gaagttattt gttgctgata
       61 cacaagaaca agctcgtgga cgttttggac ggcctttttt cgctgaacct ggacgaggaa
      121 tctacatgag tctcttgctc catccagaca aacggtttga tgaattgcct caatatacga
      181 tcatcgcagc cagtgcctgt gtgaaagcca ttgaatctgt aaccggtcgt tctgcttcga
      241 tcaaatgggt caatgatatc tacatggatg gaaaaaaagt ctgtgggatt ttatctgaag
      301 cagtcagtga tatggaaagc ggcaggatca gtcatatcat cattgggatc gggcttaatt
      361 tttctgttcc tcaaaatcat tttccagctg atctccaaga aaaagccatc tctgtctttc
      421 ccgacggaca agctagtgtc acaaggaatc agctaatcag caaaatctgg caagaattgt
      481 tcacttatct ttctcaccca gaaaaagcgt tggacttcta taaagaaaaa tcattcgtat
      541 tgggaaaaac cgtgtcgttc aatcaaaaag gaacgactta tgtcggtctt gcaaaagaaa
      601 tcggtgatca tggcgaactg atcgtccaaa caaatgaaca gaagatgagt ttgtcttctg
      661 gcgaaatcag tctcacatct atccgtacgc aataattatc agatttcaca aaaggacacc
      721 tgatctcata cagtgtcctt ttttctgaat tctcttcaaa agactctcct tattctatca
      781 gctgacagtt tctctatcct ctagaaaaag gtattctaaa aatatctata aagcatggta
      841 cactttcttt aaatgaatca atgcaaaaaa caagagagtc atcagtttac acgatcaaaa
      901 gagatagcag gccgcttcct ttttcaatct tatagataga ccatgggtaa cgataaaaac
      961 aaaaaagaac ttgcgactta ttttgccgta agttcttttt tagctagtgc cttaatctct
     1021 taatcccaac aaacgtctcg catagatcac ctgaccagag tgcatagcag catcatcaat
     1081 aatagaaacg agacgcattc ctcgtgtgac tggtggtgtc cagttctcgt caattacttc
     1141 atctagctcg gaaggttcca gccttcttaa gtaagaaata gcaaaatcag cagctcctcg
     1201 caagtatcct agcagatctt ctatttgatt agcttggatc tgctttgctt gttccagact
     1261 atgcttccaa tcttgttcgt tatctgctat cgtcatcgga aaccggcttt cccagtcttg
     1321 actatgccaa attggagaag ttcctgctaa atcagcaatc tggaaatcta attctcgagc
     1381 ggtatgccaa gccagccaag tcattgattt gatctgcggg gctctatctt ccactggaaa
     1441 acgattggcc tcctcaatag agacgccttc aaacaaacgt tcaaaccgat cgtatgcccg
     1501 atccacactc tcgcatagca tatctaaata atccatttat tttcctcctt tttatttatc
     1561 ctacttactt tttcctaatt ctaggatacc tacttatatg ttactacaca cccttatttt
     1621 ttacacttta acagtcacca tcatcaatag tttggagatt gaaagaaaaa gatagtgtcg
     1681 aactatcaat tgaacaagaa gcaacaatat gaacgtttca ttaatattct ttaaataaac
     1741 aatgattttt caaacgaaca gtttaagact aggagaaaaa gagtataata ggaaaatgtt
     1801 tgaaaggaaa ggaaggggaa aaatgaaaaa aagggcaagt ttactagtcc tagttgcttt
     1861 gttgttcaat atcttttcgt atggtgtggc cgtttcagcg gaaacataca ttcctaaaga
     1921 ccctgggaat atttataatg atctaactgg taactatggc ttgttaggaa ttgctagtca
     1981 attccacgta tttgctaaaa ataagacaac tgtgaatgca catacagacg gaaatatagc
     2041 aacacatgaa cttgatgcaa aaaataattt tggtacagag cttcatgaag gtttattgaa
     2101 ccaagaaata aattatatac aaaaaactga ttctttcgct aattcttcag gcatacctac
     2161 aggtagcaca agaatgaata aatttgtcgt tggcagtaac gtggatgtag cacttcaaga
     2221 tggtcatcct acagtcaatg gatccaggct tgatcactta actccagatg atttttataa
     2281 agatcgtgct gggcatgaat atattgattt cgagcaggaa tttgctaaat tgaatgtagc
     2341 agcaaatgat cttgcaacga tcactccagc taaaacatat actgctgcag attttccaga
     2401 catgaacaat cggacaatcg atttaactga tttatcagat accgggtttt tattggtaaa
     2461 tatcgatgca gaagtgttaa cgatgaatac gccacttcaa atcattaatc caaatgatca
     2521 agtagttgta tttaatgtca tcaacagttc ttctgcattg aacgtacagt caccaatcaa
     2581 atacaatgat cgttcaaatc atgaaacaga agatttttcg gatgcgaata tctcttggaa
     2641 ttttggaaat gagatgactg atttgacaat cagtgctcct tttcaaggaa caatccttgc
     2701 gcctaatgct actatccgca ttactcaaaa ccaagacgga acgattatag gaacaaatgt
     2761 gattttagat gcagctacca atcgttggga tcctaacgaa atatttatca gcgacaatgg
     2821 tacagatacg acagacacaa gcgacagtac agatacatct accacaagtg atagctcaga
     2881 ttcatca
//
LOCUS       DADGKS010000185         2846 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.192, whole genome shotgun sequence.
ACCESSION   DADGKS010000185 DADGKS010000000
VERSION     DADGKS010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2846
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.192"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            5..1087
                     /locus_tag="JXV47_003065"
     CDS             5..1087
                     /locus_tag="JXV47_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017414133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAX1489029.1"
                     /translation="MNDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTDT
                     RVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINAE
                     FKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKIIS
                     LEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVKN
                     DGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKEDG
                     ELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISIT
                     MDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1294..2436)
                     /locus_tag="JXV47_003066"
     CDS             complement(1294..2436)
                     /locus_tag="JXV47_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAX1489030.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2441..2626)
                     /locus_tag="JXV47_003067"
     CDS             complement(2441..2626)
                     /locus_tag="JXV47_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAX1489031.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
BASE COUNT          943 a          523 c          443 g          937 t
ORIGIN      
        1 agatatcaat gatgatggct caagaaaaaa agtggagaaa gttggcggag acacccgacc
       61 agaggccgaa gctgctttac gaaaagtttt atcagatatt gacgaaacag gacaatactt
      121 tttaggtacg gatactcgag taaaacaata ccttgatttt tggatggagg aatacgttaa
      181 actaaatcta aaatacaata cctatgaaaa ctaccgattt accatcaaaa atcatataaa
      241 cggttattta ggaaagaaaa aacttacgga tctctcccct gctcttttac aaaatttcat
      301 caatgctgaa tttaaaaagg gttactcgaa gaaaacaatg actattactc actctgtcct
      361 taagaatgcg ctgaatatgg cggtttatcc ttggggatta atcaagcaaa atcctatgct
      421 gtatgtaaaa ataccaaaat atgaagcacg accaacgact aaaaaagatc taaaaatcat
      481 ttctcttgag gactttgatc atatgctaga aattactcct gaaggacatc ctttctatat
      541 tcctttgaat attggatttt atacgggaat gcgcgttggc gaagtttgtg gtctgacgtg
      601 ggatgatgtc gatttttcaa atggaacaat tactgtagag aaacaaatgg taaagaatga
      661 cggcgcatgg gtatatggta cgccaaagac aagcagttcc aatcgaacga tttttattgg
      721 acaaaccttg ctagcaattc tgaaaaaaca taagaaacaa caattagaaa atcgaatgaa
      781 gtatggaaag ctctacattg attcaaatgc agtatgtacg aaggaagacg gtgagctagt
      841 tacgccaagt gtagtgaaat ggaatactag gaggatatcg aatgcactct ccctctcttt
      901 taacttccat tctctcagac atactcatgc tacacttctt ctcgaaaatg gcgcaaaaat
      961 gaaagaaatc tctgaacgat tgggccacag cagaatttca attacgatgg atacttactc
     1021 gcatgtaaca gataagatga gaaatgaaac ggtcgatatc atggaaaatc ttagaaagaa
     1081 ttcttgattt ttgccaccga aaaaaaccac cggtggcaaa tccatgtaaa catggtttat
     1141 tttttacact gttttcaaac aaacccttgc tatttcttcg gttcgtcctc gtccattttc
     1201 gataccgaca gctagcttat aacccaaggt atatcaacat aaaaaaataa aaataggcta
     1261 tgacagcagc gtgacagcaa aaaagatgga aagttaaata tcaaacctcg taatttcatt
     1321 tgcgagtgct tgatttgttt ctggatataa gtgtccatat ttgtccaaag tagttttaat
     1381 agaggcatga cctagacgct tagatattgc atagatattt ttattatgtt caattaaaaa
     1441 ggcaacatgc gagtgtctta atccatgcat atgaattggt tttactcctg caatttcagc
     1501 tagttttttt attctgctta aaatagttct tggagatggc ggtaatccat caaaagaaaa
     1561 aaccaattct atatttttcc caattgattg ttgagttttt ttccatgttt ttaaatcttc
     1621 aacggtttgt ctgtctaacg aaattatccg aatacttgat gtattttttg tttcagcaaa
     1681 ttcataatct tgtcttgtac ggatgtaaat tgacttattt acgctacatc tgccatttat
     1741 taagtcaaag tctttccatt gtaacgctaa gagctcctca ctccttacac ctgtaacaaa
     1801 aataaaacgc atcaaacgtt tataaaattc ttcataaaaa tccccgtgat aaacactatt
     1861 atatactttc ttaaattcat caactgtcca aaattctact tgaggacgct gagtttttat
     1921 tttacctata gtatctacag gattttcttc aataatttca agtacaattg cccttttaaa
     1981 aactactctc aacttattga atatctgttt aatataattt ggtgataatg gttgctcaat
     2041 gccctttttt acaacatgga ttttcgataa aaactgttga aattcctgta tatgaattgg
     2101 tcgaatcttt acaacctgca tttctccaaa aaaatccaat gcacgttgta aaatatgatc
     2161 tgttttcata tatgtttttt ctacagttcc caacttatac caaggaaaaa aatactctcg
     2221 ataaaaatca tgaaacgtta ttccttgcag ataaattcct tgtgaatcag aaaaactttg
     2281 ttttaactct tcgagtcccc ttctagcttc tccttgagtt ttgaagcctc ttctggtcac
     2341 ttgaattctt tttccaaagc gatcttgtcc taaagttgca gaaaaaaacc aagtgcctct
     2401 ttttctgtct ttataaacat tcgcaatttt cctcatttta ctattcctcc caagaaatat
     2461 ggagaacttc ttctaaaatt gaaataggaa ttctttttat ttttgaatta cgataaaaaa
     2521 agtatccttt ctcaactaaa agttctttac attccttgaa gattttatta gcatagtact
     2581 gagaaaaacc tagattaatc aaatcttttc gagtagctgt tttcattata gcaccttcct
     2641 tacttttttt catttatttc tatcagctgc ttttgtcaaa agcacatagg aatttcacct
     2701 ctccccaagt ttacggcgag ccttacggaa gtatcattat cccaacttta aatcatcgct
     2761 ttttattgac tataaaaatt attttagaat atttatcgct ccttctttac agcaagaaat
     2821 catggcgcaa ctaaaatatg ctcctt
//
LOCUS       DADGKS010000186         2821 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.193, whole genome shotgun sequence.
ACCESSION   DADGKS010000186 DADGKS010000000
VERSION     DADGKS010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2821
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.193"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..1649)
                     /locus_tag="JXV47_003068"
     CDS             complement(<1..1649)
                     /locus_tag="JXV47_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489032.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGDYDYSENPNLMPYITEPWVG
                     PLLGNGHTVKDSVKRVITHTKTRTANSGDILSLGLGIPCTAEANNRYLITTLRPSTTY
                     TLSVTMSVGSDWTGETNTIGVRLRYLNEQGGIELPINALIPANVERDKMVTHTFTGIT
                     KDNVTSITNCYVEIFSLNSEYKGTVSVSYDVKLKAHYPNLLDGPYWLGKVPLGENIAD
                     PTVVFPHKTSEYMVYGRRNTENYIADQTYTISMKATKLTVQSFAVYIAAGRVKVGDMK
                     PTEGLANTWELTFTVTKQHIDSGVTNYLEIYQYPSATKGAVQIEWLKLEKGNTRTPNI
                     SEYKYRGTGMRDSNNPKDYVWDLAPEYVEDNLATDIKISEIT"
     gene            complement(1673..>2821)
                     /locus_tag="JXV47_003069"
     CDS             complement(1673..>2821)
                     /locus_tag="JXV47_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489033.1"
                     /translation="GGEISDLLNDIVDHQTDMITGQNGGYVLLDPKEAPSRILIMDTP
                     DKNTARNVLQINNAGIGFSKTGINGTYETAWTLDGGFNASFITAGEIVGITIRGTTLI
                     SDGADYRTSIANGKMTWYSKKVNKDIMELEARDYVSADAGIVSYTMKTGGGFMIRNPQ
                     GNLVFSTWDNGNNRPFLSFGAPNFRYSNASYVTSGDGSSLSINGSAGNSWEFKVAGRT
                     MKFTSDGMLTLPGCFFGSWEDGKLARFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLL
                     NAYETPEYYFADYGEAVTGDNGKVRVDIDPMFAETVNLSRYMTHVTPTELVLCAVTHE
                     DIDHFIIETSKPNVLVRWNLVAHRLGYEDIRLKEDTAYDSTVLDQKRF"
BASE COUNT          824 a          598 c          444 g          955 t
ORIGIN      
        1 gtaatttcag aaattttaat atctgtggcc aaattatctt cgacatattc tggtgctaga
       61 tcccaaacat aatcttttgg attgtttgaa tcacgcatac cagtaccacg atatttatac
      121 tcactaatat tcggggttcg agtattgcct ttttctagtt tgagccactc aatttgaaca
      181 gctccttttg tagctgacgg gtattggtat atttccagat aattagttac cccactatct
      241 atatgttgct tagttacagt aaaagttaac tcccatgtat tagctaaccc ctcagtaggc
      301 ttcatgtctc ctactttaac gcggccagca gcaatataca cggcaaacga ttgaactgtt
      361 agtttagttg ctttcattga tatggtatat gtttggtcag cgatatagtt ttctgtattg
      421 cgtctaccat aaaccatata ttcactagtt ttgtgtggaa agacaactgt agggtcagca
      481 atattctcgc ctaaaggaac tttacctaac cagtaagggc catctagtaa gttagggtag
      541 tgtgctttta acttaacgtc atagctgaca ctaaccgttc ctttatattc actattaagt
      601 gagaatattt caacataaca gtttgttatg ctagttacat tatcttttgt tataccagta
      661 aatgtatgag tgaccatttt atcgcgttct acatttgctg gtattaatgc attaatgggc
      721 agttctatac caccttgttc atttaaatat ctaagcctaa cccctatagt attggtctct
      781 ccagtccaat ctgaaccgac actcatagta acgcttaatg tgtatgtcgt agatggtcgt
      841 aaagtggtta taagatacct attattagct tccgctgtac acggaatacc taagccaagc
      901 gataatatgt cgccggaatt agctgttcta gttttagtat gagttataac ccttttaaca
      961 ctatctttaa ctgtatgtcc attacctaac aaaggtccaa cccaaggttc tgtaatatat
     1021 ggcattaaat tcgggttctc cgaataatca tagtccccga agtcgatgct gttactgtac
     1081 atcacttgta agttacctaa cttagaaatt tcttctttca gagcatctaa cttgtcttgt
     1141 agcgttttag cttgaccagt taaatcagta atctgttgat ttaagctatc cactctacct
     1201 ttgatttcag ccataaaagc atcaaaagtt tcgttgtact ttcgaatcaa ctcttctaat
     1261 tgcgaaacat attcatcggc ttggccttgc gaaatgtcag acactcctag tgagaaaaaa
     1321 atgatatctt gcgttgttaa aatttgattg tcttttctat attctacgta gcagtgttta
     1381 taatatcctg cttcactcat aaatgtgcca tcaagagaaa acgtgacttc ttcactagtt
     1441 acactagttg caacattatc tacgtaacgg ttagatggtg ttgttccttt taaagtaaat
     1501 gttccgccac tcgtatccat ctgcaagcca tttagaaacg gtttaaccgt caccgtaatc
     1561 cctttatcac cttgacgagc cataatagct ttggtgtagt ttaattcttt gctgaaatct
     1621 aaagccaaat tatataaact gctagccatt tatatacctc cttgtcttcg ttttaaaaac
     1681 gtttttggtc aagcactgtg ctatcatatg ctgtatcctc ttttaatcta atatcttcat
     1741 accctagacg gtgtgccact aaattccatc taactaatac gtttggctta ctagtttcaa
     1801 tgatgaaatg gtcaatatct tcatgagtaa cagcacacaa aactagttct gtaggtgtca
     1861 catgtgtcat ataccgactt agatttactg tttcagcaaa catggggtca atatcaacac
     1921 gaactttacc attgtcacct gtaacggctt ccccataatc agcgaaataa tattctggag
     1981 tttcataagc gttcaatagt cgttgtccat aatgttctgt tggtacagtt gagtttttag
     2041 tacctctaac agtaaaatct ttatatactt gtaccgttga ttgttcaaac ctagcaagtt
     2101 tcccatcttc ccatgaacca aaaaaacaac ctggtaacgt tagcatacca tcactagtaa
     2161 atttcatagt cctaccagct accttaaatt cccatgagtt acccgcacta ccattaatgc
     2221 ttaaagaact accgtcgcca gaagttacat aactagcatt gctatacctg aaattgggcg
     2281 caccaaaaga tagaaacggt ctgttattac cattatccca cgtactaaaa accaagttac
     2341 cctgtggatt tctaatcatg aaaccaccac cagttttcat ggtgtatgat acaataccgg
     2401 catcagcact tacataatca cgtgcttcta gctccataat atctttgtta actttttttg
     2461 agtaccaagt cattttgcca ttagcaatac ttgttctata atcagcacca tcactaatta
     2521 atgtagtacc tctaatagta attcctacta tttcaccagc cgtaataaac gaggcattga
     2581 atccgccatc taacgtccat gccgtttcat atgttccatt aatgccagtt ttagaaaaac
     2641 caataccagc attgttgatt tgtaaaacat tccttgcggt attcttatct ggtgtgtcca
     2701 taatcaaaat acgactaggc gcttctttag gatctaataa aacataacca ccattttgac
     2761 cagtaatcat atcagtttga tgatctacaa tatcattgag taaatcactg atttcgccac
     2821 c
//
LOCUS       DADGKS010000187         2739 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.195, whole genome shotgun sequence.
ACCESSION   DADGKS010000187 DADGKS010000000
VERSION     DADGKS010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2739
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.195"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(10..1242)
                     /locus_tag="JXV47_003070"
     CDS             complement(10..1242)
                     /locus_tag="JXV47_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAX1489034.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1497..2066
                     /locus_tag="JXV47_003071"
     CDS             1497..2066
                     /locus_tag="JXV47_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAX1489035.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2244..2684)
                     /locus_tag="JXV47_003072"
     CDS             complement(2244..2684)
                     /locus_tag="JXV47_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HAX1489036.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
BASE COUNT          823 a          550 c          495 g          871 t
ORIGIN      
        1 aaagtatact caagcccaat cgccatttcg gaaaatcggt actgtagagc catcttcacg
       61 gattccgtcg atatccatct tgtcagatcc taccatgaaa tctacgtggg tttgacttct
      121 attcaatcca gcttctgcta attcttcatc ggacatttct gtaccgcctt tcacactgaa
      181 ggcataagca gaacctagtg ctaagtgatt cgatgcgttt tcatcaaata atgtattgaa
      241 aaagatgatg ccagattgag aaataggtga agggtcaggt acaagtgcga cttctcctaa
      301 acgacgcgca ccttcatctg tatcaagcag ttttgctaag acatcttctc cttgttcggc
      361 agaaaaatca acaacttttc catctttaaa agtaaatttc atacccgaga tgatggtgcc
      421 agcataactc agtggctttg tacttgaaat gtaaccatct actcgatgac tgtcaggtgc
      481 tgtgaacact tcttccgtcg gcatatttgc catgaatttt tctccacgag cattatagct
      541 tccagcgcct tcccaaagat ggtttttagg caatccgata atgatatctg taccgggagc
      601 agtatagtga agggcagaaa attgttctcg attcaattct tctgcttttt ttgctaattt
      661 ttcatcatgc ttcttccatg ctaagacagg gtcttcttca tagacacgag tcgttttgaa
      721 aatctgatcc cataatgcct caacttgttt ttcttctggc agttctggga agacttttgc
      781 tgcccattgt ttaccagccg cagccacgac agtccaactg actttatttg cttgagttgc
      841 cttgcgtaaa ttcattagtg ctttgccatt cgctgattga taagacgcta ctcgatggct
      901 atctacacca gcaaatgcat cgggatcggc agaaacaacg ctgatcctgc ttgctccttt
      961 ttcaagccat tcatccgctt gatcgatttt agattgtggt acattctcaa tacgatccgt
     1021 tgcagcatgt aaaagaaatt ctctttggat ctggtcgtca gtccattgaa cgataacctc
     1081 agcggctcct agtttataag cttcttgtgt gatcaatcga gcaaggggtg cctgttccac
     1141 gctgatctgt aaaacaactg tgtgtccttt ttctgtggct acgccagttt ctgcaattaa
     1201 gcgtgcatat ttttttagaa gttcattaaa atcagataac ataataaaaa ttcctcctca
     1261 ccattttttc tggtaactat tagcatgata ccatttaatt atgattcaaa caatgaggct
     1321 ttaaataaaa aaaggaggtt atttttttaa ggttaagttt catgatatat gttactactt
     1381 gctatttcag cttgtgaaga aaatcaaaaa ctaattttgc atatcaaaaa aaacatgtta
     1441 caatgaaatt aatcaatggt ggaagcgtta taaaaaaatt aaggagatta aaaaatatgg
     1501 caagaaaaaa gacgattact agagaacaga ttttggcagc tgcttatgaa gtagctgcca
     1561 ccgatggatt tacacgattt actgcgagaa acatcgcgaa caaaatgaat tgttccacgc
     1621 aaccgattta tcttgagttt aaaaatatgg atgacttgag acaagctctt tttgagcaga
     1681 tctatgatca tttacaatat gaagtgttca ctgttgagca tacagggaat acgattatcg
     1741 atcttgcttt taattatatc cattttgcaa gaagagagaa gaagttgtat cgttcactgt
     1801 acttagaaga atatggtgga ggaaaagaga tgcagaattt ctcttatact tactttgtga
     1861 atacagtgaa acgcgatcca gcttatgtga atctttcaga agagcagatc gaatctttgt
     1921 ataatgggac atggatcata gctactggga tcgcagcttt gatgtcttca agcatcatcc
     1981 atccaactga tgaacagatt gaaaagatga tccaagacag tatagatgct atcttgaaat
     2041 tcaaagaacc aatcgaaatc gattgaatat actcaaaagt tccacaaatc agtaggtaac
     2101 aagagatgtg tcaaaataag gaaaagttcg tttttcttac agcgtatgca tttttaactc
     2161 ccgaagaact cttccatgaa tgcaatgaat aaaagagcca tacagattga ataaatctgg
     2221 atggctcttt tattgcaagt atattaaatt tttgcgacta gttctttagc gaaagcttct
     2281 aaattttcga tatcttcttc ttcagcattc agatccactt taacattttc ggctcctttt
     2341 gatgcgcctg tttttgcaaa agcagcatcg aaatcatcca ccgatttgca gaattcatcg
     2401 taaaaagtat caccagatcc gcagacaccg taaatttttc ccaatagatc caattcttgc
     2461 aagtcttcat aaaagtctac gatctcatca ggcagatcgc catcatcgta tgtataagta
     2521 gctactacgc aaatatctgc ctcctcgaat tcatctgcat ctacttgggt acattcgttg
     2581 atttcgactt cgatatccag attttcaaat gcttctgcaa caatatcggc gatttcttca
     2641 gtgtttcctg tcatgctagc atatacgatt tttgctaaag ccatgatgtg cctcctcgtt
     2701 tataattatt taacaattat gaattatacc aaaacatca
//
LOCUS       DADGKS010000188         2719 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.196, whole genome shotgun sequence.
ACCESSION   DADGKS010000188 DADGKS010000000
VERSION     DADGKS010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.196"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            700..2610
                     /gene="ltrA"
                     /locus_tag="JXV47_003073"
     CDS             700..2610
                     /gene="ltrA"
                     /locus_tag="JXV47_003073"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAX1489037.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
BASE COUNT         1065 a          420 c          556 g          678 t
ORIGIN      
        1 aaaagctaag gcactaataa aagaacgaaa aagtttggtt attaggagaa ctgataatct
       61 gacaggtgga atgatgaagt aacgctctga aacgcctgcc ctgagcctcc gacaagcatt
      121 gtatgaggaa actcagaatg tttgaagctc ggtaaagacg gctgaaagat accgtaatag
      181 ttgatgaaca tatatcttct atcgaaaact atccagaggt gggtagcgta tccaacaggt
      241 cgggggtcta taaaatatct atggttagaa tgttctataa ggaactgacg aaacagcgaa
      301 tgtacgggtc taaatttgaa ctttgtagaa atgcaaaggt acgagaaatc gtagctggtg
      361 tggcaaagta agaatatagg ttatgaaatg ccatataacg ttacaggcgg tatcaagcca
      421 gcaggcttat agctagtgac ctaaggatat atatgtatag ataagattat cggaacgagg
      481 aaaggtattg ggttctcatc aagagaataa actgacgaag aacaataagc agttgaacta
      541 atgctgaaaa gcagagggcg aacctaagaa attcttgtaa tgagaatgga ggaatgccct
      601 caagtcgtgt atatattaga aaagtattat gttgtttcaa taaggattac gagtaagata
      661 aaaaagctca ctcaatttca agtaaaggag tgaagcctta tgcctaaaaa taaaaatgaa
      721 acattgtgtg tagaagattt aagacacgct gaatattacg aaatgcaaaa cacctttgat
      781 gatttatatg ccaaaagtaa gaatggagat attttcactc atcttatgga tattatccta
      841 tcgagagaaa atatattact ggcatatcga aatatcaaag caaatgcagg cagtaaaaca
      901 gcaggaacag acggtacaat aattaaagat attggcaaat tgccagcaga aacagttgtc
      961 aaaaaagtaa gatacattgt tgcaggcagt ccacatgggt atcgacctaa gccagtgagg
     1021 cgaaaagaaa taccaaaacc aaatggtaaa accagacctc taggtattcc ttgtatgtgg
     1081 gacaggctta tacaacaatg tataaaacaa gtattagaac caatctgcga agctaaattt
     1141 agtgaaaaca gctatggttt tagacctaat aggtcagttg aaaatgcaat aaaagcaacc
     1201 tataaccgcc tacaaatcag ccagctacat tatgtgattg aatttgatat taagggtttc
     1261 tttgacaacg tgaaccattc caagctgata aaacagatat gggctatggg aatacgggac
     1321 aagcacttga tattcatttt aaaaaggata ttaaaagctc caatcaaaat gactaacggt
     1381 acaataacat atccagagaa aggaactccg caagggggaa taatatcccc actactagca
     1441 aacattgttc ttaatgagtt agaccattgg gtagaaagcc aatggcagga aaatcctgtt
     1501 acaaaaaact atgtggttca tatcaataaa agcggtagcc catgtaaaag caacgcttac
     1561 aaagaaatga agaaaacaaa gttaaaggaa atgtatatgg ttcgttatgc agatgatttt
     1621 agagttttct gccgctacaa ggaaagtgct gaaaaagcca aaatagcaat cactcaatgg
     1681 attgaacaac gattaaaatt ggaagtatca caagaaaaaa caagaattgt aaatgttaga
     1741 aaaagatact ccgactttct tggtttcaag attaaaatga taccgagaag aaagaagtta
     1801 gttgttaaat cacatataag tgataaacaa ttcaaaaacc aaaaagacaa gctggtatca
     1861 caggcaaaga aaattgcttc tccctcaaaa gggaaaacgg aattagaaga aacaagactt
     1921 tataattcaa tggtattagg tatgcaaaat tattatcaga ttgcaacgaa tgtaaatctg
     1981 gattgtatga aactgaatag agctgtaatg gctatcttca ctaacagatt aggtacaaac
     2041 aaaaggggca gattgagaaa aacaggcaga caacttacga caaaggaggc aacaagatat
     2101 ggtaaatcta aaatgcttcg gtatgttgct ggcgagggcg aacctatttt ccctgttgga
     2161 tatatccaac acagaaaacc aatggcaaag gtgtatttag cgaattgcta cactctagag
     2221 ggaagaaaat ttatccacac caatctaagt gttgataaat tactgatgta ccagttaatg
     2281 aaattatctt tggaaaatcg cacaatagaa tacgcagaca atcgaatttc gctattttct
     2341 gctcaacatg gaaaatgtgc tataactctg gaagaatttc aacaagctaa tgaaatacat
     2401 tgtcatcata ttgtaccaac tggagctggt ggaaatgacg attataaaaa tcttattttg
     2461 gtaaaagagg cggtacaccg tctaatacac gctaaaacag aagaaacaat acaaaaatat
     2521 atagctctat tgaagctaaa taaagtccag ctcataagac taaataaata tagagtatta
     2581 gctggcaatc aagaattaaa cttgatatag gtctactaca taaatacttt tcaatataaa
     2641 cacgatggaa cgcggagtgc ggtgaaagtc gcacgctccg tgtgaatggg gggaaaagtt
     2701 tgagatattt ataatatca
//
LOCUS       DADGKS010000189         2641 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.197, whole genome shotgun sequence.
ACCESSION   DADGKS010000189 DADGKS010000000
VERSION     DADGKS010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2641
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.197"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..742
                     /gene="radA"
                     /locus_tag="JXV47_003074"
     CDS             <1..742
                     /gene="radA"
                     /locus_tag="JXV47_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HAX1489038.1"
                     /translation="IFIVGHVTKEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVK
                     NRFGSTNEIGIFEMHEHGLEEVANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQA
                     LVTPTMFGNAKRTTTGLDFNRVSLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAID
                     LAIAVSIASSYKEKGTQPTECFIGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKN
                     NLGNWEAPKGIEIVGVATLAETLKRVFR"
     gene            776..1933
                     /locus_tag="JXV47_003075"
     CDS             776..1933
                     /locus_tag="JXV47_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HAX1489039.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            2103..>2641
                     /locus_tag="JXV47_003076"
     CDS             2103..>2641
                     /locus_tag="JXV47_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HAX1489040.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESD"
BASE COUNT          875 a          478 c          600 g          688 t
ORIGIN      
        1 catttttatc gtcggtcatg ttaccaaaga aggctcgatc gccggcccaa gaatgttaga
       61 acatatggtg gatacggtgt tatattttga aggtgaacaa catcatagtt ttcggatttt
      121 gcgagcagta aaaaaccgat ttggctcaac gaatgagatt gggatttttg aaatgcatga
      181 gcatggattg gaagaagtcg ctaatccttc acagattttc ttagaagaac gcctagacgg
      241 tgcaactggc tctgctatcg ttgtggcaat ggaagggaca cgtccaattt tggtagagat
      301 ccaagcatta gtcacaccta ctatgttcgg aaatgccaaa cgaacaacaa caggtcttga
      361 tttcaatcgg gtatctctga tcatggcagt gctggaaaaa agagctgggt tgcttcttca
      421 gaatcaagat gcttacttaa aagctgcagg tggggtaaaa ttaaatgaac cagcgattga
      481 tttagctatc gctgtcagta ttgcttcaag ctataaagaa aaaggaacac agccaacgga
      541 atgtttcatc ggtgaaattg gactgactgg agaaatcaga cgtgtcagtc atattgaaca
      601 acgagtcaaa gaagtccaaa aactcggctt cacaaaagta tacctaccta aaaacaactt
      661 aggtaactgg gaagcgccaa aaggaatcga gatagttgga gtagcaactt tggctgaaac
      721 gttgaagcgt gtgttccgct aactaataaa tgattgtcga aacggaggaa aaacgatgca
      781 aaaacgtgtc attactttgc tgatgatcat tgtcggcgca agcttgggta tttcattttt
      841 accctcagct tggcaggcaa tcggtcaaca gtcaaacgga tggctgaata atacatttac
      901 caacagcctg ttaggcgcac ttattttctt tttattatct ttgctgttgg ccaaacatat
      961 ctcagctatt atcaaacaag tagaacaaaa actaagtgag gtcagcttga cttatcttct
     1021 cttcggtgcg atcggtgcga tcatcggatt gactttaggt gttgtgatct cgacccctct
     1081 ttacaatatg gaaattccat tcgtcaatag tgtattgccg attttactga tgatcatctt
     1141 aggctatctg ggattgagaa tgggaacgac acgaatcgaa gaatggaaga aagtttttgg
     1201 ttcacgaagc aaaaaaatcg agcaagaaac agctagtcaa gttgagagtc aactgttaga
     1261 acgaaaatca ggagaaaatt tccataaata taaaatcttg gatacaagcg tgatcattga
     1321 cggtcggatt tatgatatta caaagactgg attcttagaa ggaaccttga tgatccctaa
     1381 ttttgttctt tacgaactac aatacatcgc ggactcaggg gatagtttga aacgtgtgcg
     1441 tggtcgtcgc ggattagata tcctaaatgc cttgcaaaaa gaagagggta tatctgtcga
     1501 aatgtacgat ggagactttg aagatatcag tgaagtagac agcaaattga tcaaattggc
     1561 taagctttta gatggtgtca ttgtaaccaa tgactataac ttgaataaag tctctgaatt
     1621 ccaaaatgta cctgttctta atatcaatgc gttggcaaat gccgtaaaac cagtcgtcat
     1681 ccctggtgaa acgatgaatg ttctagtagt aaaagccggg acagaacgcc aacaaggagt
     1741 agcctacctt gatgacggca cgatggttgt cgtagaagat ggacagcatt acatgaatga
     1801 acgtatcgaa gtcgttgtaa caagtgccct tcaaacagct gctggacgca tgatctttgc
     1861 taaacctgca catgcaggac gaggaatcga caataaaaaa gagacagaga aaaagactaa
     1921 acaatcaaaa taaaaaagaa attcagccaa ctggtaagga aattcaacca gttggcttta
     1981 ctatttacct tagaaaaggt aaaatttgtg ctgagtggct ttaaataaat gatatttgag
     2041 aagccgtaac tgacggaatt tttgctgtta gtcaaagtct agtttgaaag aagaggaaga
     2101 aaatgacgaa agtacgcgta cgctatgcac caagtccaac tgggcacctg catattggaa
     2161 atgcaagaac tgcattattc aattatttgt ttgcccgcca caatgatgga gactttatta
     2221 ttcgtattga ggatactgac caaaaacgta atatcgaaga tggcgaaaaa agccagttgg
     2281 aaaaccttgc ttggttggga atgaattggg atgaatctcc tgaaaatcct ggagaatacg
     2341 gcccttaccg tcaatctgaa cgtaaagaaa tctatcaacc gctgattgat cagctgcttg
     2401 ctagcaatcg agcatacaaa tgctattgca cagaagaaga attagaagca gaacgggaag
     2461 cacaacgcgc aagaggagaa atgcctcatt acgcaggaac atgtgcgaac ttgacacctg
     2521 aagaacaagc agaaaaagaa gcacaaggtc tagaatctgt tgtacgtttc cgtgtgcctc
     2581 gcaatacaga atacgcattt acagatatgg tgaaaggcgc tatttcgttc gaatccgata
     2641 a
//
LOCUS       DADGKS010000190         2632 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.198, whole genome shotgun sequence.
ACCESSION   DADGKS010000190 DADGKS010000000
VERSION     DADGKS010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2632
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.198"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..437
                     /locus_tag="JXV47_003077"
     CDS             <1..437
                     /locus_tag="JXV47_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAX1489041.1"
                     /translation="NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNI
                     FPTKHAVGIQTDAGIEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQ
                     SAGKNTDMVVVFTNGDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(769..1620)
                     /locus_tag="JXV47_003078"
     CDS             complement(769..1620)
                     /locus_tag="JXV47_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAX1489042.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            1743..2210
                     /locus_tag="JXV47_003079"
     CDS             1743..2210
                     /locus_tag="JXV47_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HAX1489043.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(2473..>2632)
                     /locus_tag="JXV47_003080"
     CDS             complement(2473..>2632)
                     /locus_tag="JXV47_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAX1489044.1"
                     /translation="ELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEI
                     WIPVVNKP"
BASE COUNT          803 a          574 c          438 g          817 t
ORIGIN      
        1 caaatgggaa actgattcca atcactgaag tttcagatga tgtattcgcg gaaaaaatga
       61 tgggtgacgg ctatgctgta ttaccagaaa atggagaaat cttctctcca atcgctggta
      121 cgatcacaaa cattttccca acgaaacatg ctgtcggaat ccaaacagat gctggtatcg
      181 aagtcttgct tcatatgggc atcaacactg ttgacttaaa aggcgaacca ttcactttat
      241 atgtaaaaga aggtcaaaaa gtcgcaagag gtcaattgat tgctttagtt gatcttgccg
      301 ctattcaatc tgcaggcaaa aacacggata tggtcgttgt attcacaaat ggcgacaaag
      361 tccaaagctt agaaatcgaa cccgcacgtg atgtaaaagc aaatgataaa atcggctctg
      421 tttccaacaa agcctgagcc atcgtcttcc ccagactttt ttatcgataa acaaacagga
      481 gctgagacaa aaatcttgtc tcagctcctt tttccgaata aaaacggcgt tctcctgcca
      541 actccgcggt aataagtcca gccaaacgta acatatgaag agctattttt tatttgactc
      601 ttcttattac ttgatgcaga acagcttttt tacaacctct gataaacggt gttcaaaaac
      661 cagtttatcg gtatgaagtc aaatttatgc aaaaatgtgg aaagccattt tcacaaaatt
      721 tttcttcata ctcaaaacta atcggctttt tcacaacctc tttatacatt attcctgatc
      781 caatatttct tttaatgctg cttcaagaga agttaatggt tttcccaata ctttttctaa
      841 atcatcagag gaaatagcta actgatcctt tttaatatca tgttggatcg ctaaaaacat
      901 gtcagctgct tcttgaggga atccggcttc ttttagattt tcgacaaacg ctgcatcact
      961 tgcttcaata atttctaact ttttacctgt cgcacgctct aatgccttgg ctaattcttc
     1021 atagtcagtt agattgccgg ataattctaa gatttctgga gagtcacttt ctactagtac
     1081 ttttgctgca gcttctgcat attcacgttt caatgcccaa cctgtttttc catttcctgc
     1141 agcataaacg aattgaccag tttttaaagc ctgcccaatg ataggtaatt cattctctac
     1201 ataccaatta ttccgtaaaa atgtatggga aatacctgaa tccttaatca ttttttcagt
     1261 gaattggtga tctggcgcta atacactgat cgagtgatcg gcatctgcaa aacttgtata
     1321 agcgatataa gataccccag ctgcttgtgc tgccttcact acattcttat gttcggcttg
     1381 acgatttcct ggaacgccag agacaaaaag caatcgatct attcctttca acgcttcttt
     1441 cattgagtct aaatcatcat aatcaccaat acgtatatta aatccagctt ctttcagtgc
     1501 ttctcctttt tcttcactac gtactagtac atagatttca ttttgtggaa ccatcttttt
     1561 taagaattcc agcgcataac caccaaaacc tccagttgct cctgttacta aataatgcat
     1621 atttgccact ccctattctt tttatttgtt aagatttaca gctgtacatt tataaattac
     1681 acctttatca taaagagtgt ggtaagataa gtcaagcaaa aaaaatgaaa ggatgacaac
     1741 tgatgaagta ttctctgcaa tttagtgatg caatccatgt acttgcctat attgaaatgt
     1801 ttcaagatac ccgatcactt tctagtgaga tgattgccag tagtatcgaa acaaatgcag
     1861 caaatgtacg taaaatcatg agtcagctca aaaaatccgg tttgatcttt acaaaaaccg
     1921 gaaaaccgca gccttccctt gccaaaagtc cagatcagat ttctttacta gatgtctatc
     1981 gcagcatcga aggtaataca cagcttatcc aagtcgatcc aaaaacaaat ccaaattgcg
     2041 tcgttggtgc gaatatccaa gaagctttag aagaaagcta cgctcggctg cagaaaaagg
     2101 cagaagaaga aatggctaag atcacacttg atagtctgat acataaaata gccgttttgg
     2161 aaaaagaaaa aagaccagaa aacacaggcc tcgtagagag atttttataa ttctctctac
     2221 tgtgcctgca tttttctgat cggaatcgtc tacataaatt cttttattct ccgggggaca
     2281 aaagccttgt catgcccctt tttcctctct aatgctcagg tcaaagcgct gaagtcatga
     2341 cgtcttgata aacggtgttc aagtagctga ccctcggcat tagttctgaa aaatgcaaaa
     2401 tatggaaagc tatttcccat ttttcctctc taatgctcag gtcaaagcgc tactttcacg
     2461 acctctatat tatcatggtt tattgactac cggtatccag atttctccca tatatttccc
     2521 gttggtaact cccatttcga ctacagcatt tggaccccca acataggcgt aatcttctac
     2581 ttctcttaaa acatgcccaa aggccgtatt cgtcaaatca tttcttaatt ct
//
LOCUS       DADGKS010000191         2536 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.199, whole genome shotgun sequence.
ACCESSION   DADGKS010000191 DADGKS010000000
VERSION     DADGKS010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2536
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.199"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..586)
                     /locus_tag="JXV47_003081"
     CDS             complement(<1..586)
                     /locus_tag="JXV47_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAX1489045.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRE"
     gene            complement(649..1176)
                     /locus_tag="JXV47_003082"
     CDS             complement(649..1176)
                     /locus_tag="JXV47_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HAX1489046.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            1406..2212
                     /gene="proB"
                     /locus_tag="JXV47_003083"
     CDS             1406..2212
                     /gene="proB"
                     /locus_tag="JXV47_003083"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HAX1489047.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            2209..>2536
                     /gene="proA"
                     /locus_tag="JXV47_003084"
     CDS             2209..>2536
                     /gene="proA"
                     /locus_tag="JXV47_003084"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Catalyzes the phosphorylation of L-glutamate during
                     the proline biosynthesis pathway; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-phosphate reductase"
                     /protein_id="HAX1489048.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGK"
BASE COUNT          751 a          527 c          495 g          763 t
ORIGIN      
        1 tttctcttac ttggctgaca cttcctgcca cacttgtgat gtctggctgc gtcatcgttt
       61 ggatggaatc aatgataaca taatcagggg agatatgttc gatggcacga ctgatttcgt
      121 tcatatctgt ttcagcgtat agataaaatt ctgtgttgat acttccgagg cgttccgcgc
      181 gtaattttat ctgctctgcg ctttcttcgc cggatacata taagactttt ccgcctatgg
      241 ctgctaattg ctgagaaact tgtaacagca aagtggattt cccgatacct ggatcgccac
      301 caatcaagac catagaccct ggcaccacac ctccgcctaa cacacggttc agttcttcta
      361 attttgtttt gatccgaggt tcttttttag ggacgacgtc tgcgattttt gttggttttg
      421 ctttttctcc tgtcaaactt gtccgagttc tgcggtccgt tgtatcttgt tcgatttctt
      481 cgaccatcgt attccatttt ccgcaatttg ggcagcgtcc caagaactta ggcgacacat
      541 acccgcaatt ttggcaaaca aattgtactt ttgatttttt tgccattgta ccgcctcctt
      601 ttatcctaat catgagacat taaatcaagc ttaagtatct ttaacgtttt atttactgga
      661 agaaccaaat ccgccttgac gttgagcagt cgtttgatct tgatctgctt ttaaaaacgg
      721 caaaaagatc ccttggccga tacgctcgcc ttttttgatc actacatcct tgaaaccaaa
      781 gttggtgaat tggaacatga tatggccttc atttgcctca ttattgtaat aatcactgtc
      841 aatcacacct actccgtttg tcaacactaa aaaccgcttc aacggattgc ttgaacggtt
      901 agcaagctgc aaaaattcat cttctcccat gtaagctttg attccagtag gcacgagggt
      961 tggtttcaat tgtttttcat tttctgatac atcttttttc aatccatctg cgactgtttc
     1021 caaccccttt ttccagcctg ctttccagat acttggaatc acgacctctt ctgctgcttc
     1081 aaaatcatag ccagcagcat gatgtgtagc gcgctgcggt agattgatat tttgatcttt
     1141 atatttagaa ataacttcaa atcctctttt tctcaccggt tttcctccct aaataaacta
     1201 ctcctattct aacatatccg aggctgtaaa agactttctt tacaaattct tcaagaaatt
     1261 ctgctatctt aaagtaaacc attaattcgt tctttttcca aacgactgca agttgtacaa
     1321 aaaaactatt ttttacatga ctttactcgt caaaacaagt agaatagaac gaaattaatg
     1381 agtggatatt tgattgaggt gtcacatgcg taaagaaatt aaaaatgcaa aacgaattat
     1441 tgtcaaagta ggaacaagta cattgattta tcccaatgga aatatcaatc ttgcggcaat
     1501 cgatcagtta gcttttgtcc tttctgatct tagaaatcgg ggaaaggaag tgatcttagt
     1561 ctcatcagga gctgtaggcg ttggtatgca taaattacat ttgtcagaac gtccgacttt
     1621 gattcctgaa cagcaagctg cggcggctgt tggtcaagcc gaactgatga atatctataa
     1681 tcaaagattc agtgtatata atcaacagac ggcacagatc ctcgtgacaa gagacgtggt
     1741 agattatcct gaaagtcgta aaaatgtgag gaatacattg gaacagcttt tgattatgga
     1801 cacgatccct atcgtgaacg aaaacgatac tgtagcagtg gatgaattag atcatctgac
     1861 aaaatttggc gataatgatc agctgtcagc catcatggca aaacttgtcg cggcagacct
     1921 tttgatcgtc ctttctgata tcgacgggtt ttattcagat aatccgacta caaatcccga
     1981 ggctcagatg tatcgctata tcgataaaat cgatgaaaag attctggcac aagcaggtgg
     2041 tgctggtagc acatttggaa caggcggtat gcagagtaaa ttaaaagccg cttctaggat
     2101 atttgaagca aacagcgcaa tgattttagc aaatggaaaa aatccggcaa ttatttttga
     2161 tattcttgca ggaaaagaag taggtacttt atttaaggag gacttgaaat gactgacttg
     2221 atgcaattag gacaacaggc aaaagatagc gcgcaacaac tagcacttat gcctacaaac
     2281 cgcaaaaatg agctacttgt tcaaatggca caaaccatca aaaagaatca acaagcgatc
     2341 attgaagcaa atcataaaga cttagaaaaa gcagtcgaaa acaatatcag tgaaacgatg
     2401 caagaccgct tgcagctgac acctgagcga atcaatgcca tggctacaga gatcgaaaaa
     2461 attgcttcgt tagacgatcc tattggaaaa gtagatgaga tgtggacgaa caccgacgga
     2521 ttgagaatcg gcaaaa
//
LOCUS       DADGKS010000192         2516 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.200, whole genome shotgun sequence.
ACCESSION   DADGKS010000192 DADGKS010000000
VERSION     DADGKS010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2516
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.200"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..209
                     /locus_tag="JXV47_003085"
     CDS             <1..209
                     /locus_tag="JXV47_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1489049.1"
                     /translation="LMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKH
                     RVYKQLVTNYENANDWRLDNEKFL"
     gene            163..1935
                     /locus_tag="JXV47_003086"
     CDS             163..1935
                     /locus_tag="JXV47_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002841847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1489050.1"
                     /translation="MRMQMIGGLTMKNFYKKKFALTDQGAEALTKASISSFFVYCINM
                     VPAFIIMMLIDELVLENAKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLR
                     VQIADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVM
                     LLVGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEI
                     NSFNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLL
                     TGEVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSP
                     LKSFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDY
                     DEGCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAA
                     RLANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLD
                     AENEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSE
                     IYKNLIKKTKLSEKFVYEKEAQSR"
BASE COUNT          885 a          337 c          462 g          832 t
ORIGIN      
        1 atttgatgaa agaaaaaaca gttattatga tagctcatcg attatccagc attaaatctg
       61 tagatgaaat tcttgtcttg tcagaaggaa aaatagtaga acgtggaaat cataatgaat
      121 taatggctaa acatcgagtg tataaacaat tggtcactaa ttatgagaat gcaaatgatt
      181 ggaggcttga caatgaaaaa tttttataaa aaaaaatttg ctttaactga tcagggcgca
      241 gaagctttaa ctaaagcttc tatttctagt ttttttgtat actgcattaa tatggtacca
      301 gcattcatta taatgatgct gatagacgaa ttagttttag aaaatgcaaa gccccgttgg
      361 ctttattttg cagtatcgtt tgttactttg cttttcatgt attggttgtt agatagggag
      421 tatgaaaact tatataatag tacttataaa gaaagtgcgc atttaagagt gcaaattgca
      481 gacgatttgt caaatttacc attatcctat ttttcaaaac ataatttatc agatttatct
      541 caaactatca tgtctgacgt tgaaggtatt gagcatgcga tgagtcatgc aatacctaaa
      601 gccggcggta tggctctgtt tttccctttt atttcagtga tgcttttggt tggtaatgtc
      661 aaaatgggat tagctgttat tttgccaacg ttatttagtt ttgtcttaat cttgttatca
      721 aagaaatccc aaacgaaagc caatactaaa tattacgata ctttgagaga aaactcggaa
      781 gaatttcaag aaactattga attgcagcaa gagattaata gctttaatct atctaaaaaa
      841 gttcaagaca gacttttcaa aaaaatggaa gagagtgaaa ggattcattt aaaggtagaa
      901 ttaagtactt tttcagtcat ggccttatcc tctattttct catatgttag tttagcagta
      961 gtcattctag taggtgttca cttactgtta acgggtgaag tgactatact ctacgtcgtt
     1021 ggttacttac tagccgcaat aaaaataaag gattccttcg attctatgaa agaagcagtg
     1081 cttgaaatat tttatttagc tcctaaaata cagcgaatta gagctatgaa ggaaaccagt
     1141 atccaagagg gatcagatag tcctctgaaa tcttttgaca ttgagttgcg agatgtctct
     1201 ttctcatatg ataacaatac cccaatttta gatcatatct cttttacggc taaacaagga
     1261 gaagtgactg cgttagtagg tgctagtggt tccgggaaaa ctagtatctt gaaattagtg
     1321 tctagactgt atgattatga tgaaggctgt attttaattg atgggtatga tattaaacgt
     1381 gtatctccag cttctttgtt tagcaaaatc gctattgttt ttcaagaggt aactttgttt
     1441 aatacaagta ttttggaaaa tatacgtatt ggaaatagtc aagcgtcaga tgaggaagtg
     1501 aaaaaagcag ctcgtttagc taactgcgaa gactttattg aaaaactacc tgacggttat
     1561 catacattgg tcggagaaaa cggaagttca ctttctggag gagagcgaca acgcctatcc
     1621 atagcacggg cttttttgaa aaatgcgcca attttaattt tagatgaaat tactgccagt
     1681 ttagatgcgg aaaatgaaaa acgtattcag gaaagtttaa atcgtttaat acaagataag
     1741 acagtactaa ttatatcgca tcgcttgaag tctattgaaa aggtaaataa aattgtagtg
     1801 atggatcaag gaaaactagt tgatcaaggt actcataatg agttgtatcg aaggtcagaa
     1861 atatacaaaa atctcataaa gaaaactaaa ctatctgaga aattcgtcta tgaaaaagaa
     1921 gctcaatcac gatgatgaaa taggctttaa attaacctac aatttttggg atatagttat
     1981 aattcttttt caaaaagaat aattttatta aacagcatct aattttgaat acacgaaaga
     2041 atcagtatga ttgaattagt tcacttaatg tctattctta taatataagg aataatcaaa
     2101 gttttaaaaa attggcgata aaccagttaa acataaaaga ttgaataaaa agttatagtt
     2161 tctttcatat tgccgtttta agtagaggaa aagctactta aaacggtatt tgtgtttgat
     2221 tggactaata aaagtgaatt cttatttttc agagcctaaa ctgcatattc ttttaaatga
     2281 tttgattatc tctatgtacc gataaattcg ttttcaaata gttatctatt catatgagtt
     2341 ttatttcatg ttatttattg ttgacaagag caactcttgt tggtaaagta tcagtgtcaa
     2401 aacgtaacga ttacgatttg aggtgtctaa atcaaaataa aaggagtata aaggtatatg
     2461 gcaaaaaagt cgaaaattgc taaagcaaag aaacaaatgg cgatgattga aaagta
//
LOCUS       DADGKS010000193         2398 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.201, whole genome shotgun sequence.
ACCESSION   DADGKS010000193 DADGKS010000000
VERSION     DADGKS010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.201"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            207..2069
                     /locus_tag="JXV47_003087"
     CDS             207..2069
                     /locus_tag="JXV47_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAX1489051.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2398
                     /locus_tag="JXV47_003088"
     CDS             2069..>2398
                     /locus_tag="JXV47_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAX1489052.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          865 a          353 c          466 g          714 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataat
//
LOCUS       DADGKS010000194         2364 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.202, whole genome shotgun sequence.
ACCESSION   DADGKS010000194 DADGKS010000000
VERSION     DADGKS010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.202"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            150..1451
                     /locus_tag="JXV47_003089"
     CDS             150..1451
                     /locus_tag="JXV47_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAX1489053.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
     gene            complement(1555..1755)
                     /locus_tag="JXV47_003090"
     CDS             complement(1555..1755)
                     /locus_tag="JXV47_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAX1489054.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT          768 a          453 c          408 g          735 t
ORIGIN      
        1 cgtacaaaaa aaccgtcttt tcttggctct ataatttcta ggactgatag aaaatcattc
       61 tatcggtccc ttttgagcat gaaaaaacaa aacatacaga agctccgtta gaattgaatc
      121 accacaacac aatcaaagga gcgttctgta tgcctgatct tcatcatatc aaactactac
      181 ttggaatcaa agataaaaac attttcatca caaatgtgga atcgaagagc attaagaata
      241 tcaagagtct tgttgtttct gcgacgttaa gtaaagaaat tcgtcgctgt cctttgtgta
      301 aacagatgaa tcatgaaggc atgatcgtta agaacggaaa gaaaaaatcg ctcattcaac
      361 ttaataaatg tgcgaaccaa ctgacttatc ttgctttagc gaaacaacgc taccactgtc
      421 gtggctgcca cacctatttt acggcgaata cctacattgt cgatagaaac tgctttatcg
      481 ctaaacaagt gcgctataaa attttagaag agctaactga aaaacaagca atgacgacaa
      541 ttgctaagca ttgcggcgtt tcttggtcga ccgtttctcg gacactcgct tctctgatcc
      601 ccatgacaaa agtaaaaaga aattggttac cgcgttgttt attaatggat gaatttcgtt
      661 cactgaaaaa tcaagtcggt ccctactcct tttcttgtat ggatggcgat actggaaaat
      721 tactggatat tcttccttca cggaagaaaa aggctctcgt ttcttatttt atgcaatttg
      781 aacgacgcgc acgattgaag gtaaaggtca tcgtgacgga catgaatgtt tcttatgcct
      841 ctctgataaa ggaatgtttt ccaaaggcaa aactcgttgt ggatcgtttt cacattgtca
      901 aacatctcat tcgtaaattt gaggatattc gcgtacgaat catgaaaagc tttgatcgaa
      961 acgatccaac acaagccaaa tattatcgac aattaaaggc gttgtctcgg cttctgatca
     1021 aacgacagga caagcttgtt tatgacaaat ggaccaaatg gcgcaatttt ggttgggcgt
     1081 atctcaccga aagtgaagtg gtggatcgtc tgctttcgat ctctgacgaa ttacgaatcg
     1141 cctattttta ctatcaagaa attcttcaag cgtttcacga caaagaggcg gacactttct
     1201 ttaaacttgt aagaacgatg cccaattccg ttccaaaaga actgcattct ataaaaaaag
     1261 cttttataaa ctatgaatcc ggcattcgtt tagccctcga attgccttat tcaaatgcca
     1321 aaatagaaaa tctgcatacc cacatcaaag cattgaaacg agtcgcttat ggctttcgaa
     1381 gctttcggaa aatgaagacc agaattttct tactaaataa tctgattacc tatgaatcaa
     1441 aaaacatcta aagtagaaaa ggaattctac cttagatgtt cttatctcac tctatcagtc
     1501 ctatttgaca aagagccctt ttctttcgaa aagacggtta aaagtcaatt tttattaagc
     1561 tttaacaatg tttgttgctt gagggccacg ttgaccatct tcaacatcgt aagacactgc
     1621 ttggccttct tctaaagttt tgaagccgtc accttggata gctgaaaaat gtgcaaatac
     1681 atcatttcca tcttcaccag tgataaagcc aaaacctttg tctgcgttga accattttac
     1741 tgtaccgtta ttcataaata aattcctcct gatacgtatc aatgtacgtt ttttcgttgc
     1801 aataaatatt tgataggcaa aaggagtttt atctatgtag atatatcgct caaattacgt
     1861 ttcaaaatag attactcatt taatatatca tgctttttct aataacacaa ggataatgca
     1921 atgaaatata aaattcattg tcttctattg tcttcgaatc gaagaaaaag ttgaataacc
     1981 gcgattgatt cactttttgt tttcttgttt atttgctttt atctgcaact tttgacttta
     2041 aaatttctta actatgaaaa cctttcaatt ggtggtatac ttataaatgg aatttcgtta
     2101 tcaacgcgtt cgttgccttt cagcaagtat ttaaagaaag gagaatggct atgacattct
     2161 ataacaaaga tatacaatat cgagtaacct tggatacaga tttgaatcta tttgtcgttt
     2221 ttgacaaaga aaataccaat catgtagcga caggtgttac gatcgaacaa gcagtgcaag
     2281 aattaaaaaa atctgcataa ggagtggaaa ccctcatatg gacgattctc gttcttctct
     2341 ttaaacgcat ctactggtag ataa
//
LOCUS       DADGKS010000195         2340 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.203, whole genome shotgun sequence.
ACCESSION   DADGKS010000195 DADGKS010000000
VERSION     DADGKS010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2340
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.203"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(365..1657)
                     /locus_tag="JXV47_003091"
     CDS             complement(365..1657)
                     /locus_tag="JXV47_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAX1489055.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
     gene            complement(1931..2191)
                     /locus_tag="JXV47_003092"
     CDS             complement(1931..2191)
                     /locus_tag="JXV47_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489056.1"
                     /translation="MKKIDLINMIGMLIGILVNIVIFTDWLGVLFSNLIPILIIGICG
                     IILSILELFESRNTMNRIFACIILIVNLLPMVYFTFLYFALG"
BASE COUNT          781 a          441 c          355 g          763 t
ORIGIN      
        1 tatgggctac tctgtgatac ttattagcca ttaaactatt ttacccacat agcatatatt
       61 ttgaaatcgt tcattccgta aattcaacta aatatgccta aaaaaataaa aaatctaaga
      121 tagaataaga tttattcagt cttagatgga tttatagcaa ctttttcgta acaactttaa
      181 aaaatacgaa aagaaagagc tgttttactc tgactacgtt gctaaattgt cgtttaatca
      241 ttcatttaaa ccaaatcttt ttttatagaa ttcgttttaa tcctcctgaa tccaaaaact
      301 atgaaaaccg taattaaata gttaagagtt tttaaccacc ataattctct cggctatttt
      361 gaaatcagat aaattttgat cggacacata gttgaataaa cctaccgttg ttacggaagg
      421 taaatcgcat acttttcatt ctagaggaga aggtctcgtt gatcattaac tgattaagca
      481 ccatagccca gttttgaatt cgaccacctg accacttcgc gtgtaattct ttcgtgcgta
      541 aataaagtag ttttaggagt gcattctcat tagagaacgc tccttttttt gtgacttttc
      601 tgaagctgga gtggacactt tcaaccgcat tggtagtgta cataattttt cgaatggcac
      661 taccataatc aaatagttgt tcaacatgtg caaagttccg tttccagaca tctacagcac
      721 cagaataatg agaccaccga ttttgaaaac tgtcaaaagc agcatgtgca gcgtttagag
      781 aagaagcacc gtagaacttt ttcatatctc ggcagacttc cttatagtcc ttacttggaa
      841 tatagcgcaa tgcatttcga acaagatgaa caatacagcg ctgaacaatt accgatggaa
      901 agatcgcttt tgcgccttct tcgaggccag aaacaccgtc catcgaaatg aaaaagacat
      961 cttcgacacc acgtgctttc agttcatcaa atacttgcat ccagcgattt ttagattctg
     1021 tttgatttaa ccataatcct aaaatctcct tatttccttt gagatcatag ccaagaatgg
     1081 tgtatacagc atattctttg gcttcataat tttctcgtaa agtaacatac atacaatcaa
     1141 cgaatagaaa ggcataacac tttgctaggg ggcgggcttg ccattcttcc aattcaggaa
     1201 ggacagcgtc agtgatatct gaaatcattt catgggaaat atcaaagcca taaatagctt
     1261 cgacggttgc ggcaatatct cgttgactca ttcctcgtgc atacatggaa agaaccttcc
     1321 cttcgatgtc ggagacatct cgttttctct taggaattaa ctctggttca aaggaagctt
     1381 cccggtctct aggaacatca atagctactt caccaaaact ggttttaagc gttttagttc
     1441 catagccatt tcgacggtta tcgtgttcct taggctcttt agaatgggca tcataaccta
     1501 aatgattatt caattctcct tgaagcattt tttcaaaaag gggcccaaac acatctttca
     1561 aagcatcttg catgtcatcg acagattcag gttgataggc attcagaatg gattcagcta
     1621 acttttcggc atcaggattt cttttctttc tagccatcgt gtaatcacct cttgatctta
     1681 ttgtagaaaa agaaaaaccg cgaagcaacc acctgcctag gattaatggt tacttacacg
     1741 gtttatatta cactctcatc attaaaaaag tatctttcga tattactaaa caatgaaatt
     1801 atctatttga aatttaaatc tgataatata ttgagtgttc caatgagggc tttgatccta
     1861 ttatccatat ctttttcagt tttaatattg atacacatta taagaaaaag aaacttttgg
     1921 ttaatttatt tcatcccagt gcaaaatata aaaaagtaaa atagaccata ggcaatagat
     1981 taacaattaa tataatacaa gcaaatattc tattcattgt atttctgctt tcaaaaagtt
     2041 ctaatattga aagtataatt ccacaaatgc ctataataag tatgggaata agattagaaa
     2101 ataacacccc gagccaatct gtgaaaatta ctatatttac taatatccct attaacatac
     2161 ctatcatatt tattaaatca atttttttca ttagatattt ctcctttatt aaatctgaag
     2221 tacttatatt aaaataattc taaactattt acctcaaaaa gtgcaataaa ttatttctga
     2281 acaataaaat gatagtcaaa acaaaaaaat attgttaatc gttcagagcc atccgagagt
//
LOCUS       DADGKS010000196         2337 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.204, whole genome shotgun sequence.
ACCESSION   DADGKS010000196 DADGKS010000000
VERSION     DADGKS010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2337
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.204"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(226..2223)
                     /locus_tag="JXV47_003093"
     CDS             complement(226..2223)
                     /locus_tag="JXV47_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HAX1489057.1"
                     /translation="MIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKA
                     LVTNKANQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHL
                     KEATKRLSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVY
                     IKNSGVTDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADE
                     AEKYLAKGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGS
                     NLMLSMNAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHE
                     QGSKEITENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKS
                     SVFNRSGQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRD
                     SFKEFGLGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYT
                     PIQLAQYASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMA
                     ILREGFHQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGP
                     TDNPEIAISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          597 a          522 c          425 g          793 t
ORIGIN      
        1 tgagccagaa tgtggttcat tctgactcag atttgatttt gcacaactca tcagtcctta
       61 ttgacaaaga gccacaattt ttgtcacaac cttttttgcc gagtaaacgg tgttcaaaag
      121 ccagtttctc ggtatgaagt caaatttaag caaaaatgtg agaagctatt ttcacaaaat
      181 ttttcttcat actcgaaact aagcggcttt ttcacgacct cttttttatt ttgccatgaa
      241 catatcataa tacgcgtcca ttatttcttt agcaatcgtc aagtttatgt ggtcttgttc
      301 gtctaataag ttcggcaaga caacactgat ggcaatttcc ggattgtctg ttggtccgta
      361 tgccacgata ttactattga ctgtcgcaat atctggatga ccttccgcaa ccgtttctgc
      421 agtccctgtt tttgcggaaa ggtccatttt cgcactggct aatggtttgg ctgttgtgta
      481 aggatcggta ccatggacaa cttggtggaa tccttcacgg aggatcgcca tattttctgc
      541 agaaatattg accgtatttt ctactgttgt gccaatttct ttcttcactt cacccaagtt
      601 tccattttcg tcattgccat agatcgcttt gactaggtgc ggctgtactc gtttcccgcc
      661 attagcgact gttgaagcat attgagctaa ttggattggt gtatatgtgt caaactgtcc
      721 aaatgccaaa tcggtaaagt tacctggagc ataccattct ttgccattat ccgcattgaa
      781 cttcttcata taatcaacag aacgtgagat cccaggagat tcattcggca aatcgatccc
      841 agtcgttgta ccaagaccaa actctttgaa agagtctctc aattgctgat aagctttagc
      901 ttcttcatct aaactaggta gtcccattcc aggtgtatag tctagtccta acatctttaa
      961 cgccactttg atcatatacg tattagaaga caattccgat gctttgactg catcaagagc
     1021 aacttgtccg cttcgattaa agacagagct tttttctgaa gcaccttgca gacgaatcgg
     1081 ctcatcaatc aaaacttgat ttccgctgat cgcgttactt gcccagcctg ctgtcaaagt
     1141 accagccttg actacagacc ctggatcaaa ggcgctagta atcgtgccta aagcattctc
     1201 ggtgatttct ttggaacctt gttcatgact gaaaccagtc attgctagca cttctcctgt
     1261 ctgaggattc atagccactg cataagcacc aggcgaatac tgtgctttgc cgttgttgat
     1321 caatgtttga taattccttt tcaaaatttc ttctactttt gattggaatt ctgcattcat
     1381 agataacatt aaattagaac ctttttcccc agagaagatt tctttttgat tcgaaacatt
     1441 tccttcatta tcaagggaaa cttcatattg ggttttggtt ccttgcagga catcttcata
     1501 ttgtttttcc aaataacttt gtcctacacg gtcattccga gaataacctt ttgctaggta
     1561 tttctctgct tcatctgctg gaagtccttg cttttcagtc gtcacactgc caagaatact
     1621 tttcagtgaa cttgctgcat tatattctcg tgtccagtct gtgccagtcg aaactcctgg
     1681 aagttcagaa gcgcgttctg ccacaacagc taactcttga tcagtaacac cagagttttt
     1741 gatatagaca gtgtttaatt catatgcact attcatccgt ttaaagatgg tagcaatttt
     1801 taattgctcc tcgtttaaat taatctcatc agctgtgact ttattgacca tcgcactata
     1861 ttgttcgctg ttccctaatt gcttttcttt tgccgaaagt ctttttgtgg cttctttcaa
     1921 atgtttggga tcagccagcc aaaaatcttt tttatctcta tctgtcagat tttcatctac
     1981 cggaacatcg atcagcgagt tcagcttcgt tgcgatttca agcaaatctt tagccgtaac
     2041 ttgtgttcct ctcgtatatg tgatggcctg attcgcttta ttcgtaacta aagcttttcc
     2101 tgtggagtcg tagatcattc cgcgaggagt actttcttgg accgtaatcg tagaagtaga
     2161 cttcactcgc gcctccatct cttcgccgtt cacgatctgc aaataaccca atctagcaat
     2221 caacgcaaca aataacgtaa atataatgaa aaaaagaaaa tttaagcgaa aaggaacatg
     2281 ggaccggcga aacgttttgt tcttaggttc ttgtgcacct tttcttattt tttctaa
//
LOCUS       DADGKS010000197         2313 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.205, whole genome shotgun sequence.
ACCESSION   DADGKS010000197 DADGKS010000000
VERSION     DADGKS010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2313
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.205"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            191..445
                     /locus_tag="JXV47_003094"
     CDS             191..445
                     /locus_tag="JXV47_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAX1489058.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            446..763
                     /locus_tag="JXV47_003095"
     CDS             446..763
                     /locus_tag="JXV47_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAX1489059.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1322..2257
                     /locus_tag="JXV47_003096"
     CDS             1322..2257
                     /locus_tag="JXV47_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489060.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          846 a          313 c          434 g          720 t
ORIGIN      
        1 gatgttaacg gaagtgtatg gtgagtagtt cactcgtatt ttgatatcgt ttgtatatgt
       61 tttcagcgtt ctaagtggct tattttgtcc aataataata tggagtggaa tcccttaaga
      121 aacaccgttg gcaattgttg ttataacatg ttataattta ttcatcaaaa actaaaagga
      181 gtgtgataac atgggaaaag aactaaaggt tagaaagatc ggcaatagcg tgggagtgat
      241 ccttccaagc tctcttggat taaaaagcgg agacattatc caagccaaac aagaaggcaa
      301 cttattcata ttagatacta ctcaaatagc aaaagaacac gatcgcaaat tgattgaaga
      361 aagtttccaa gactttgaga aaggtttaac agtttcagaa attgaaatgg taaaagcttt
      421 cggaaaatac ggctggagtg aatagatgaa agagtacacg ctagtttatt ctaaaagttt
      481 tcagaccagc cttgaaacga taatagaaga atgggaaaat gagcttgctc tttctccagc
      541 cagcataaaa agatttgtag gtgcgatcca gaaggcttta gaactaacca aaaattttcc
      601 aactatgcat gaggaagttt ccgaaatcta tggaatggat atcccaacat atcggatcgt
      661 gatcggcaaa agctatgcct tattttatcg gatcgaccat gaaaaaaaag agatacttgt
      721 aggacgtatt ttccaatcta aacaaatgaa actaggcttt taacaataat taggaaaaag
      781 tcgctcatcc tctacaggtg ggtgattaat gccgctcgat atggttgtta accgtcggtt
      841 actcgaagat tgatatataa gacttagtac ctttttattt tgctccatgt tatggccgaa
      901 ggtctaaaga tacaatcatt agtctagaga aaaattaaga accgtaggaa ctacggggat
      961 cgcttggtga ataagagaca ctgctattag tgaaaaaata agatatcaag tacgctctat
     1021 tcccaaaaat ttcgtgactt tactcatgag aggttcaagt agtatatttt taatcaaaat
     1081 tgacgtaact tttaataaat actacctaaa taaggtagta tttatttttg tgttttaaaa
     1141 gaggaagtcc aatatatcta tgggaaactt cttaaatatt atgttggtac atgaaaatat
     1201 acatccctgc tagactattt acaacatttt actttgtacg tattcttgtt ttaaaaggaa
     1261 tgggataaaa tataggtaca ataactattt gatgctaaat ataattaatg gaggagagat
     1321 agtgaacata cttaatgaaa aaagatatgt atggtttgct ggtaaaaaat atattactac
     1381 tttcaaaaga ttatccgagt taatgcagca gactgttaaa agtgctatgc ctgaaggata
     1441 caagtttaat tttgttcaat cttcagtatc tactgaaagt atctattttt caattctttc
     1501 tgagagtagg ctttttcatt ttagaataag ttctcatgta aagaaaactg atgttgatat
     1561 atatacgttc cgtacaaata attataaaaa tttaaatgat ttgagtagaa gtatcagtga
     1621 atatctcaag gggaatagct atctcaagat tcgattttca catatattaa ttttactacc
     1681 atatttgaat gagaatttca ccctaattca agtagataag tctttcattg cctcaggtaa
     1741 tcaaggaaat atgaatatta caagtaacaa aacgtcacgt gtgctattgg cgttgatggg
     1801 ttacggaatt ctttatagag atgaccaaaa tggccagatt ctaataaatc gggctgggcg
     1861 ttcattatta atgaaatata gaaaatttat accggaagat tttcaaaact tacagttaga
     1921 aaacatgcgt ttagaagatt tatttagatt agcagaagat gataagtata gatttgaagt
     1981 tttgaaaatt caaaagaatg aactattgaa taagttatat cctgagaatg cgataaaagc
     2041 acattttggt gatgctaatc atatgtatag ttggttcatt cctaaaagat ttagagggaa
     2101 aatcaatgct ggagatcaag tgaaagtact caatcgaaat agtacagatg tcgtaatgat
     2161 aacagatatc tatgtagaag atgaagatat aatcaaatat atgaagcctg tgataaaact
     2221 tgttaataaa aataaaggaa cccgtggtgc tagttaattt tttcctagag aaaaatgtct
     2281 aaacatgttg gtaaatcaac aaaaaaacgc ata
//
LOCUS       DADGKS010000198         2293 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.206, whole genome shotgun sequence.
ACCESSION   DADGKS010000198 DADGKS010000000
VERSION     DADGKS010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.206"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(51..1598)
                     /locus_tag="JXV47_003097"
     CDS             complement(51..1598)
                     /locus_tag="JXV47_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HAX1489061.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="JXV47_003098"
     CDS             complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="JXV47_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HAX1489062.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(2043..2237)
                     /locus_tag="JXV47_003099"
     CDS             complement(2043..2237)
                     /locus_tag="JXV47_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489063.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
BASE COUNT          644 a          477 c          408 g          764 t
ORIGIN      
        1 tacgtcaaat aacccgacct atagaataga atcgggaatg tttggcgttt ttagttacga
       61 gaaaaatgtt gttgtacatc cttgttccaa ggcaacagtt gatctaaagt ttctgctgaa
      121 agtacgggaa gatttggtat cttatcaaat agaaactcta gatactttac aggattcaat
      181 ccgttaagtt ctgctgtttt atatacactc agaatgattc ctgaagttcg tgctccttca
      241 agacttgtgg aatgcaacca atttttccgt cctatcacca gctctttgat atttcgctcc
      301 gcacgattat ttgtgagttc taaacgacca tcttcaaaaa taggttcaaa accacttcgt
      361 agtttacacg catattgaac ggctgcatcc aacttggatt ttgcaacagg atctatcgtt
      421 gccatccact cataaaaagc aataaataat ggacgcagtt cttgttgccg acagcttaat
      481 cgcttctcag gagaaaagtc tttccatttc ttttctagga caaaccattt atccaattgt
      541 ttgactgctt gagctgcggg aatatccgtg tttttctttc cttttggaat tgcttcgaaa
      601 aatttccgcc gaacatgcgc gaaacaatag acaagtcgta cactttccac ggcattatac
      661 ccgctatagc cgtcacagtg taaataccct gtaaactcct tgagaaaagt tttcggaaca
      721 tctccagcac gactttcgtc gtggtgataa taaacgatgg gatgctgact gtcttttcct
      781 gtacaaaact gccagtaata ggtatctgtt ttggcacttt caatcacacg ataacttgtt
      841 tcatccccgt gtagaatctc ttcttgatta agatagactc ttaatcgttc tcctaaaggg
      901 tctaacgcgt tttgcactgc tttaatatgc caattggtga tattatctct cgaaatatcc
      961 aacccatgtg tttgtttcca atagttctct tgccgatagg caggaacttt ctgaccaaat
     1021 ttcatccgga tcgtttccgc cactaaacta ttggaaccta agctattaga aatcaaaggt
     1081 ttaggaacga tcgctttttt aaaagaagaa agtccttctt tttcgcagct tttacaacaa
     1141 taggtatgtt gataatgggt gagacaatcc aacatagcct gatggaaacg aatttcttct
     1201 cgtacttttg tccgtccgat atctttcatc tgtgaaccgc aatgttcaca aaattgttct
     1261 tccaaaggaa ggagatgttc tttctctgtt ataggtaagt gtttgatttt gtctgctttc
     1321 gttcctacaa ctcgttgatg tccttttact ggaataatgg tggcagctgc ttctggaaca
     1381 cttacagaaa tttcttcatc actaaaaaga ttcaattgcc cattcgtttc ctcaaagaga
     1441 gtctctttag agcgtccaaa taatttgttg gttaaataat tgaccttttc attcaatagt
     1501 tggatttcag ttgtaagatt ctgaatggtt tgttgttgtg cttgattggt tttatgggct
     1561 tcttgaagca actgaagcaa cgtatctgta gtttccaaaa tttttcacca ccttgaatcg
     1621 aactgatttt gttacagaat accacaagaa acgcacaaga aataggggtt caacacattt
     1681 tttgtgttaa ccccccagct taaaaaactc ctttttttcc tggcaaaata gctcgaggtt
     1741 gatcgatact taatccttct aacaaccatc gaacctgttg gttcgttaag gttcgaactt
     1801 cgtctttcgt ccgaggccat tttaacttgc cgttttctat ccgcttataa cagagaagaa
     1861 aaccatcacc gtcccaatag agaagtttga aacggtcttg acggttcccg caaaataaaa
     1921 aaacggcatc ttcgtaaagc tcgagttgat actcttgttg aataagactg gcaagaccat
     1981 caattccttt tcgcaaatct gtttttccgc acacaatata aatatgtttg gtttgaagta
     2041 aatcataaag cattggacaa cagttctttc aaaatagctt gaagaatata attgttaata
     2101 ccgttataga tcaaaacttc agaaccattc tctcttttga tgcgcatcgc taacttggca
     2161 gccgcgggtt tacctttttc tggtgcactc ttttcgtttc ctaattggac aggaacaatc
     2221 tcatttaatt tatacataga aaacctccag acttcttgat agctcaagta tatcttgagg
     2281 tgcatttgtt agt
//
LOCUS       DADGKS010000199         2234 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.207, whole genome shotgun sequence.
ACCESSION   DADGKS010000199 DADGKS010000000
VERSION     DADGKS010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2234
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.207"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..185)
                     /locus_tag="JXV47_003100"
     CDS             complement(<1..185)
                     /locus_tag="JXV47_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489064.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQG"
     gene            complement(402..1313)
                     /locus_tag="JXV47_003101"
     CDS             complement(402..1313)
                     /locus_tag="JXV47_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAX1489065.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(1690..>2234)
                     /locus_tag="JXV47_003102"
     CDS             complement(1690..>2234)
                     /locus_tag="JXV47_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAX1489066.1"
                     /translation="VTVVGESGAGKSTLLNILGLNDQFSSGQFYLFNQETKHLTGREK
                     RLIKRNALSFLFQDFGLIEYETIDFNLDIGLKFSNLNVSDKRTAKYEALKKVNINKKL
                     STPIYTLSGGEKQRIACARVLLKNSKIILADEPTGSLDKRNKEQVVEILSQQASQGTL
                     VIVVTHDPYLTKIGNKKIML"
BASE COUNT          634 a          420 c          321 g          859 t
ORIGIN      
        1 ccttgaataa taaatgcgac aatccccgct ataattagtg tgcctaacac caaaacggaa
       61 aattgatgaa tatattttat atacaaatga tccattgtac ttcctgcctt tttatttgtg
      121 agaaaaacaa atccgtatac gtgaataact tctagaaata aaagaaattt gcaaaaccac
      181 tccatttatc tacttctacg tgcatttttt aatatcgttt tctttattta agattataca
      241 gaaaaatatc tagggtggct ggattctaag taaaaaaaat ttttaaaata aaaagaacta
      301 aatcaagtaa taattaaact actgttgatt tagttctaat aaaaagattt agatgaacag
      361 ttttattgat ttaaatagtt catatttttt atttataccg cttatttact acttgctgta
      421 ctagaatctg aagtgaatgt actcaaaaca ttttcaaagt ctttgtcttt gatttttaca
      481 ttagcgtctt tcaatacttc gccaattact ttattctgga aggtactgtc acttaatttt
      541 gtgtctgttg caatttcttt caattctttt ttgtatttat ccatgtcgtt gcctttgttt
      601 tggtttttca ccattttaac cacataatat tccgtagtat aagttgaagc attggtagaa
      661 gtgatcacat cagaaacttg accatctttc aacttaaagg ctgcttcttt gacttctgcc
      721 ggaaccgttg tagtagtgga atcaaatttc acttttccgc catcttcttt tgtcgtagta
      781 tcagttgact tgtctttggc taatttagag aaatcgtctc ccttatcagc agctttcttc
      841 acatcttttg catcatcttc acttgctact tggataattt gagcttccac ttctggatgg
      901 aaagattccc aagccgtttt taaatcttca tcggtcaatt tgatatgttt ctttagacct
      961 tcttgaaagg ctagactttg tttgatactg tctttgaatg tttgttctgt gtaacctgca
     1021 gatttcaatt gtgaatcaaa tgaatcaccc aattgtttct ttgtttgatc atattgggaa
     1081 tcgatttctt tggttgatac gtcatctcca tatttatctt caaatacttg ataaacgatc
     1141 aactgttgca cagcggaatc tgctccttgc atttttttca agctatccat tacttcttgt
     1201 tcgctgattg taccgccttt ataactaacg gctgtttttt caccggcatt cgtacagcct
     1261 gacaataagc cagtgcctag tacgatggca agtgctaaaa atcttttttt catttatcaa
     1321 ttctcctact tttcgttttt tgcgaattgc taaaaacaaa ggtgttcaag atgaaaatca
     1381 tcaagaacac ctttactaat ctgctcgata cgtcctgaat agatataagg ctacacaatc
     1441 cagaaagttc gctcagcaga ataaatgtca agtagcacat cacaccttaa tatactactt
     1501 cttttgttac cgtttttcaa gtctatcttg cgttccgtat ttaacgtaac taattcttag
     1561 aacaaatgtt atcgattttg tttttcttct tccgctgttg ggatattcaa atcagacact
     1621 tttatgttcg attttccaga catttttttg ttgtttttat tagaaaaagt ttgttttttc
     1681 atttgttttc taaagcatga tcttcttgtt tcctattttg gtcagatatg gatcatgcgt
     1741 gaccacgata actaacgtac cttgggaagc ctgttgcgat aagatttcaa cgacttgctc
     1801 cttatttcgt ttatctaatg atccagttgg ttcatcggct aaaatgattt tgctattctt
     1861 caataagact ctcgcacagg cgattctttg cttctcacca ccagataatg tgtagatagg
     1921 cgtacttagc ttcttgttta tatttacttt tttcaatgcc tcatactttg ctgttcgctt
     1981 atctgaaaca tttaaattcg aaaacttcaa tccaatatct aaattaaaat cgattgtttc
     2041 atattcaatc aacccaaaat cttgaaaaag aaaagagagg gcatttcttt ttatcaagcg
     2101 cttctctctt ccagttaaat gttttgtttc ttgattaaat aaataaaatt gccctgaact
     2161 gaattgatca ttcaatccta atatattcaa taaagtactt ttccctgctc cgctctctcc
     2221 aactacagtc acaa
//
LOCUS       DADGKS010000200         2182 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.208, whole genome shotgun sequence.
ACCESSION   DADGKS010000200 DADGKS010000000
VERSION     DADGKS010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2182)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2182)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2182
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.208"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..366
                     /locus_tag="JXV47_003103"
     CDS             <1..366
                     /locus_tag="JXV47_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489067.1"
                     /translation="PKANYWKKVYLDSNRLYRYLRGQKTNIKIWTAEMWAQLWNMMYF
                     NIGPKVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSF
                     VNKKKCSYAYVKAIKAVVR"
     gene            363..674
                     /locus_tag="JXV47_003104"
     CDS             363..674
                     /locus_tag="JXV47_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489068.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            664..1017
                     /locus_tag="JXV47_003105"
     CDS             664..1017
                     /locus_tag="JXV47_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAX1489069.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            1007..1408
                     /locus_tag="JXV47_003106"
     CDS             1007..1408
                     /locus_tag="JXV47_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489070.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            1401..1805
                     /locus_tag="JXV47_003107"
     CDS             1401..1805
                     /locus_tag="JXV47_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489071.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            1817..>2182
                     /locus_tag="JXV47_003108"
     CDS             1817..>2182
                     /locus_tag="JXV47_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAX1489072.1"
                     /translation="MAKTKTVVTTFDNVSIKRIAFNFKNAGNAIATNCNGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKL"
BASE COUNT          802 a          324 c          436 g          620 t
ORIGIN      
        1 cctaaagcga attattggaa aaaggtttat ctggattcta atcggctata tcgctacctt
       61 agagggcaaa aaacaaatat aaaaatctgg acagccgaga tgtgggcaca gctttggaac
      121 atgatgtatt tcaatattgg tcctaaagtt cacgaggaat tagacttttg ttttgctact
      181 gatccaatag aaaaagttaa agaagtaaaa atcttacaca atgctggagt aacaacaaac
      241 gatgaagatt tatttttcaa agggagatac gtgacttcta cgccttttga tgaagattta
      301 tcatttgtaa acaagaaaaa atgctcttac gcatatgtta aagcaattaa ggcggtggtt
      361 agatgacgcc tgaacaagtg actgaagaat tgctaatagc tgtgaaggat aatatttacg
      421 ttacctggaa cgaagaagat gagtcaatta aaaagatgat agctaaaaat gctgtttatc
      481 ttcaaagtaa agtgagtaca acactttctt tttctcctga aagcttagaa tacggattgc
      541 taatcgaaag atgtagatac gactggaatc gtgctttaga tgagtttgaa caaaatttcg
      601 ctagtgagtt attaggtttc attcaacatt atgcgctaca agaatatatt gcaggtgatg
      661 tgaatggcga ataatcgtag actcgaagaa acattcaacg atggttggtt aaagattttg
      721 acgcaaacta ccaaaagaaa tgaactagga aaaaagattg gtgtagaaga tacagaaatc
      781 acttctttaa aatttagaaa tctttccatg agagatagtg atataacagc tatggatgcg
      841 atgggatcga aattaactaa gaaagtaaag actccatttc atccaatcgc caagaaattt
      901 aataaagatc aatattttat cgtaatcgat agtatgcgtt acaacgttat ctatgccgat
      961 tacgataatt tttatatcta tttttatctt gaaagtgtgg gtgaatatgg tgattgataa
     1021 ttctaaagaa aaagaacgtt taaataagca aatttctgct atcaaaactt ccttagaaga
     1081 gcattttggc ctcaaactct ttcaagactc cgtaggcgag gatgagctac ctgatgattt
     1141 taattacttc attctcgaaa caggagaaat agaaatgatc actgagccaa aatatagcgt
     1201 gggtcaaaat ctatatctaa ctttctattc agaaaataga gaagatttaa caggagattc
     1261 actagatatt atttcattga ttcaaaatcg ttcgattcgt tttcagagaa tggatcccaa
     1321 tcatttaaaa ctagagaacc aagatcgcta tatcgatcaa ttggtattta cgtttagacg
     1381 attattgaag agtgattgtc atggctaaaa atagttggga gctaaaaata aatggacatg
     1441 atgaacttct tgtgcggatg gaacgctatt caagcgagag cgaacgactg attaacgaag
     1501 cattgaaatc aaaaggttcg gctattgcag tggataggat tacagaaaaa attcctgttt
     1561 ctgaagcaga tttaagaaga gggcaccaac acgcaaaaaa tagtcgtcca cttaagactc
     1621 aatacattaa tttgggtttc atcattagac ctacaagaaa atttgagtat ttaaaatatc
     1681 ctgatttggg gataggtact tctaaaagaa atcagccgga cgaatttatg agaagaggat
     1741 taggtcttgc acttgatcca attacagaac ttctgattcg tcaattcgat aaattaaata
     1801 aataggggga acaacaatgg ctaaaacaaa aactgtagta acaacgttcg ataacgtaag
     1861 tatcaaacga attgctttta attttaagaa cgcaggaaat gcaatcgcaa cgaattgtaa
     1921 tggacaatta gatggcgaaa cagaaatgca aacggtggtt aaaaaatgtg gagcgacaga
     1981 agtaaaatca aaatctaaac caatcaatat gacggtaaca attactgcac atgtaccgat
     2041 ggaagtttat cgacgtttca atgggttgaa acaagatgga cgtattaaac caggcattta
     2101 ctcttacggt cctgattccg taggcgaaga tttctcactt gctgcagaga tcgtggatga
     2161 cttcgaagaa aatagaaagt ta
//
LOCUS       DADGKS010000201         2163 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.209, whole genome shotgun sequence.
ACCESSION   DADGKS010000201 DADGKS010000000
VERSION     DADGKS010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2163
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.209"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(45..1364)
                     /locus_tag="JXV47_003109"
     CDS             complement(45..1364)
                     /locus_tag="JXV47_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAX1489073.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1361..2014)
                     /locus_tag="JXV47_003110"
     CDS             complement(1361..2014)
                     /locus_tag="JXV47_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1489074.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
BASE COUNT          718 a          330 c          175 g          940 t
ORIGIN      
        1 ataagtctct atttttcaat aactattgca aaattatatc ttaattaaga aaatattttt
       61 attttaaaga taaaaaattc ttcatcctgc aatactttat attctatatt gtaattattc
      121 agaatattac ttacaatata taaacctaat ccattactat tttccttatt taaatcaaat
      181 ttaacatcaa atattttatc catattcgaa attttattgt taccgtatga attctctata
      241 tataaccaat cattaactat cccaatatta attaccccat ttacatcagt atattttacc
      301 gcattactaa tcaaattaga tagaataatc tttaaagctg tttttcctat ataaacattc
      361 tcgtctaata tataattatt gacagttatt ttcttttgat ttgctaatat ttcatacttt
      421 tttaatatgt cttctaatgt atcatttatt ttcaaatatt cttcatcatt attcaaattt
      481 tctatagaat gaactgataa tatttgagaa atattttttg ttaaactatc aacgatttca
      541 atacattcat taatataaat atctctttct ttatattttc caatattgta tttcatgttt
      601 tccagtatta ttttaagact agcaagaggg gttttaagtt catgggatgc acctttaaaa
      661 aagtcatatt ttaacttttc taattttaaa atttctttat ttttaaattc caaatcgtca
      721 attgttctta ataaagtaga atacaaatca ttaatttgtt gttttaattc tccaacttca
      781 tcattagagc taacttttaa actcattttt ttatcaagtt tcatcatttt atcagtaaca
      841 atttttattt cttgtatatt attttttatt gattttgcat aaattaaaga aataatagca
      901 gaaaataaaa ttgatattaa taaagaatat ggtaaaaatt taaggcttaa atctttcgca
      961 tctttttgca tatcagctgt agaaacaaat tgtagatttg tttttttacc atcattaagc
     1021 tttatttctc tttcttcaat tatcaaagaa ttactatcac tttctaaatt aacatttata
     1081 ttatctttga tttgtatttc attcttatta tttttttctt ttatgaatac ttttatttca
     1141 ctactcttgg aataaaactc caaagtttgt tctatatatt ttatttcttt tccattcata
     1201 ttactagaaa tttcatttgc catattatga atcttttctt ttctcgtctc caaatatgtt
     1261 ttaggaaaga taaaaaaaat taatgaatga actaatataa ttattattcc aagaacagaa
     1321 aatatttgta tgaacatttt tggaaatatc tttaattttt tcattttctc tccaatttat
     1381 atcctacatt tcttatagta gttatacagt ctaattgtaa tttttttcta agttctttta
     1441 tatatacatc tattactcga tcataaggag tttcttcgct atctttccat acataatcaa
     1501 taatttgcat tcttgttaac acttgtccat tattatccaa taaacatttt aatacttcta
     1561 gttcttttgc atttacatct atttcttcac catttatttt agctgtatag ctattaaaat
     1621 taaccgatag atccttatat tcaaacttct ctaaatgtcc ataattcttc ttaattaaag
     1681 aatctattct agcttttaag accggcaatg aaaatggctt ttctacatat ccgtctacta
     1741 aattagtaaa tgcatcaatt ttatattctt catcactaaa tgcagtcaag attagaattg
     1801 gtaaattgct tttctttcta atttctttca acacttctaa accatttata aaaggtatct
     1861 gaatgtctaa gataaccaaa tttatatcgc tattaaattt tgacaaggct tctcttccat
     1921 ctttagcttg aataacagta tatccaaatt ctgaaagata ttcacttatt ccctctctta
     1981 tcatattatc atcttcaaca gttaatattt tcatatatac ctccacttaa gcctatacac
     2041 tagatattat acagcatatt atggctctat aatatctagt gttggtgacg ccttctgttg
     2101 ccaatacttt ttcttttttt taataaatgc aaacagacac cttgaaatcc tttagaaaaa
     2161 agg
//
LOCUS       DADGKS010000202         2151 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.210, whole genome shotgun sequence.
ACCESSION   DADGKS010000202 DADGKS010000000
VERSION     DADGKS010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2151
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.210"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(1579..>2151)
                     /locus_tag="JXV47_003111"
     CDS             complement(1579..>2151)
                     /locus_tag="JXV47_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAX1489075.1"
                     /translation="ISSWENSRTMPDFEMLSLLHHTLGLPIDFPSIESATESIEPTLP
                     DEPLVNKKSYSSKQPFSLKKTLSFFLLVFCLVYLFLINYQYKNETIDRFNPFLKPQIG
                     YTTLPVGYVDNSIERWVCNDIFGHGTWLSFHAGEVEKEKNHAVIKHKGKHVMNVRLLT
                     WEAIPSDYQEILSQDYDDALKRSPQEPDRH"
BASE COUNT          690 a          332 c          402 g          727 t
ORIGIN      
        1 tagctacatt gttacgcccg aattaggtga tagtgctgga ataatcggcg gattggcatt
       61 ggctagaaag gcgataagaa ataagtaatt ttaatgaata aatgtttcat tggtactcat
      121 gtcaaaagta tttaactgag taatcaaatg atgtttgata aagcgaaaat gaattcaaat
      181 aaaaaaggat cgagcaaact ggaacatttg tccgatcctt tttcacattc tatttatttc
      241 gtttattcaa ccaatcggta gagacatcca ttgcgctctt gtcgcgtggc tttgatccat
      301 ataattgacc attacgaaat catggatcat cgctttgaat gcgaacttgt gtcacatcta
      361 cttttttgac cagattttga ccagtctatt ttacattcta atgtacttat atgagttaat
      421 tttttgagta aatggtaagt ttttccttgt ttgttttatc ttaaactagt gtgtaatttg
      481 aaaatctata tggaagggtc tgtggggtaa tacttaaata aaggctagga acctgataac
      541 atcaaggttc ctagcctttt tataataaaa tgaagcgaaa ataatttctt ttaaagagcc
      601 gagattatca gctatataag agtgaatttg atgcaaaaaa cagagccgaa acagtcttgg
      661 tgttcgtagc tctgcttata tgtttcgaat ttaagacaaa gagttggcaa aagatgttga
      721 taaggaagat aagataactg tgttatataa actaggtaac taactgtaac aagctaattt
      781 taagagattc ttattagaag acgtttagga atataactaa gaaaatgatt atacaggtaa
      841 ttgtcatttc aataatgttt tctaattttc gcgtctttgt tttaagaaaa aggccagaat
      901 cagttggaaa aaagttcgta cgatagtgaa gaggggcaaa atttcctact aatattccca
      961 ctaacaagag ataaaacggc caggttggtg tgattcctct ataaaaaaat gcccatgcta
     1021 ccgaaatccc atagattaac aactgaacaa tttttacaat gaaaaaattg ttctgccatt
     1081 actcaaagtc tcttcctcct tgtatcgttt atttgtttca ttttatcatt atgataggcg
     1141 cttgaacaat ccattttgta ttttattgag tactcttgga taaactacca gcgattatca
     1201 tatttattta tgttactgta agccatcata taaaagtaaa tgagcagatc atagaaatat
     1261 aaaaaagaac taaaattgat ctaaattatg tgcagcttga ctacgtacca atctatatta
     1321 cttactagat tggtcgttaa tctattcgga tcgaatgagc aaaatatttt tgtgaatgtc
     1381 catccttgat tatgattcca aaaagaatca ttggaaggct gtggcgtaaa tattatacta
     1441 taagccagaa atacctatca ttctgaactt ttttatttag gaactttcat ctcaaggctt
     1501 tttcaattaa tttgtacccc tgttttttgg ataagatcat gtgcattgat tttttctatc
     1561 tctacgttca tctcctactt aatgcctatc tggctcctga gggcttcttt ttaaggcgtc
     1621 gtcatagtct tggctgagga tttcttggta atctgaggga atggcttccc aagtgagcag
     1681 gcgaacgttc atgacgtgtt ttcctttgtg tttgattaca gcatggtttt tctctttttc
     1741 tacctctcca gcgtgaaaag acagccatgt accatggcca aagatatcat tacataccca
     1801 acgttcgatg gaattgtcca cgtatcctac agggagtgtg gtatagccga tttgtggttt
     1861 caaaaaagga ttgaatcgat cgatcgtttc atttttgtat tgataattga taagaaaaag
     1921 atagaccaaa caaaagacga gcagaaagaa agatagtgtc tttttgagtg agaagggttg
     1981 ttttgatgaa taagatttct tgttaacaag aggttcatct ggcaatgttg gttctattga
     2041 ttcggtagct gattcaatag aaggaaaatc aatcggcaga cctaaagtat gatgtaaaag
     2101 tgacagcatt tcaaagtctg gcattgtacg agaattttcc caactagaaa t
//
LOCUS       DADGKS010000203         2149 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.211, whole genome shotgun sequence.
ACCESSION   DADGKS010000203 DADGKS010000000
VERSION     DADGKS010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2149
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.211"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..598
                     /locus_tag="JXV47_003112"
     CDS             <1..598
                     /locus_tag="JXV47_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1489076.1"
                     /translation="SIRRFCDRSYWLKNGKVVEYGDTMEVTTNYENFLKKKSVKTVDR
                     NKNQVERFAAPDIVDVTKAELLDKDKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGI
                     ALRTVDNFYVCGLNTLLDGIKIPWKKGENIFYLEYEKLGLLAGEYYFDVAVFEENATV
                     PLVYKTKYMNLFVSGSYIGEGIVVLDHKWEEGTHSNEI"
     gene            588..>2149
                     /locus_tag="JXV47_003113"
     CDS             588..>2149
                     /locus_tag="JXV47_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAX1489077.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLYINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAQPQNSNYVKVLEVIQQTKQDEIIQQIPFNNFTGENETLSFHVSELA
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKDLPEFFLTDIAG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHYLIENNTRLD
                     QTLKTTINRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSLCIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVLREEVNQAKQLAEGAKAGFELRILCEK
                     ERSFLVEAVAQNG"
BASE COUNT          760 a          332 c          456 g          601 t
ORIGIN      
        1 ttcgattcgc cgtttttgtg atcgttccta ttggttgaaa aatggaaaag ttgtcgaata
       61 tggtgatacg atggaagtaa cgacgaatta cgaaaacttt ttgaagaaaa aatcagttaa
      121 aacagtagat cgaaataaaa accaagtaga acgcttcgca gctccagata tcgtagacgt
      181 gacgaaagcc gaattgttgg ataaagataa aaatccagtg gatatgctgg aacaaggaga
      241 aaaactatac gttaaagtaa cctatgaagt aaaagacgat acaatcaaaa atccagtttt
      301 aggaattgct ctgcgtacag tcgacaattt ttatgtgtgc ggactcaata ctctactaga
      361 tggtatcaag atcccttgga aaaaaggtga gaatatcttt tatctggagt atgaaaagtt
      421 aggtttgtta gctggtgaat attattttga cgttgcggtc tttgaagaaa atgcaacggt
      481 tcctttggta tacaagacaa aatacatgaa cttgtttgtc agcggttctt atatcggaga
      541 aggcatcgtg gtcttagacc ataaatggga agaagggact catagcaatg aaatatgatt
      601 ttgaaatgga cctagatgaa caaagcagtg tgggaaaaat tgccgcacag atcaaaccag
      661 gaagtaaagt tttagagttt ggtcctggaa acggccgatt aacgaaacat ttgatcggag
      721 caaaacaatg tgaagtgagc attgtcgagc tagataagga attgttcgat tttgtcagcg
      781 agtttgccca agatggattt tatggagata tcgaaagttt tgaatgggca aactattatg
      841 ctggacaaac atttgattac gttttgtttg ccgatgtttt agaacatttg gtagatcctg
      901 gaaaaacgtt gaagaaagtt agagaatttt tgaatgaaga aggagaaatt ctaattacat
      961 tccctaacct tgcgcataat tctgtcatga ttgatttgtt caataatcaa ttgccatggg
     1021 cttcttatgg tttgctagat gaaacccata attcttttta tactcatgat ggcttccaaa
     1081 aagtttttga aaaagcagga ttatacatca atattgaaga ttatttgtac ttagctgtag
     1141 gtgatacaga attaaaatca acttatgaag aattgccgga agctgtacgt tatgatttca
     1201 aaatgcgacc atttggcgaa gtctaccaat acttcttctc attgatgaaa catccagtag
     1261 cacaaagttc cattgcgcag ccgcaaaatt ctaattatgt gaaagtatta gaagtaatcc
     1321 agcaaacgaa acaagatgaa ataattcaac aaataccatt caataatttc acaggggaaa
     1381 atgagacact aagtttccat gtatcagaat tagcagaacg aatggtgttt cgcttcgcgc
     1441 agcaacctag ctttatcgaa ttcagcgcag aagctgctgg agaaaaactc acatttatcg
     1501 attcaaatgc tgtagtcaaa acagtaaatg attgttattt gtttgatggt aaagatttac
     1561 cagagttctt tttaacggat attgcaggga aagaagtgac tatccattgt cactatcgtt
     1621 ttatcggaga attgacacca acaatgaaag aattgctgga aacaatccgt ccaatggctg
     1681 aagttacaaa gcagctttct gagaaaaatg atgaattaga aagagaaaat cattatctta
     1741 ttgagaataa tacaagatta gatcagacgt tgaaaacaac cataaatcgc tattgcacgt
     1801 tgttggaaag tgatgaatgg acaatcaaac atagattagg gcgacgtaag aaagaaacat
     1861 cgaaaaaaat ccaagaaaaa gagctttctc tatgtattga cgaaaaaatc tgggatgcag
     1921 aaacaaagat attgaaaatc atcgggtggg gaatcgctaa ttcggatcgc caaccattgt
     1981 cctataagtt atcagccgac caatcaccat tttttgaagc aattcctgtt ttacgagaag
     2041 aagtcaatca agcaaaacag ctagctgaag gagcaaaagc aggatttgaa ctgcggatcc
     2101 tttgcgagaa ggaacgttca ttcttagttg aagcagtggc tcaaaatgg
//
LOCUS       DADGKS010000204         2085 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.212, whole genome shotgun sequence.
ACCESSION   DADGKS010000204 DADGKS010000000
VERSION     DADGKS010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2085
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.212"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..881
                     /locus_tag="JXV47_003114"
     CDS             <1..881
                     /locus_tag="JXV47_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAX1489078.1"
                     /translation="GLIVFLLLSLIQKAKYGKIEEKLRALSSGNYESKLLHQPIPSAS
                     DDLYIKDIDMEITKIKEKMIEVSSELQIMTSRPQYVDGQTKEEILKLERHRLARELHD
                     SVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLHLRPVN
                     LEEKSLKQGIEQLLKELQNKIQISLKWEVEDVKLTSSIEDHLFRIVQELLSNTLRHAK
                     ANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVKIISFK
                     GQGTSVETKVPLMKEA"
     gene            888..1520
                     /locus_tag="JXV47_003115"
     CDS             888..1520
                     /locus_tag="JXV47_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1489079.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     ALRPDVILMDLVMEEMDGIESTKAILKDWPKAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNDPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            1660..>2085
                     /locus_tag="JXV47_003116"
     CDS             1660..>2085
                     /locus_tag="JXV47_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HAX1489080.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLE"
BASE COUNT          745 a          320 c          471 g          549 t
ORIGIN      
        1 taggattgat cgtatttcta ttgttatcac ttattcaaaa ggcaaaatac gggaaaatcg
       61 aagaaaagct tcgtgcactt tcttctggca attatgaatc caaacttttg catcagccga
      121 tcccaagcgc gtcggatgat ctgtacatca aagatattga tatggaaatt actaaaataa
      181 aagaaaaaat gatcgaagta tccagtgaat tacagattat gactagccgt cctcaatatg
      241 tagatggaca aaccaaagaa gagattttaa aattagaaag gcatcgatta gctcgtgagc
      301 ttcatgattc agtttcacag caattatttg cagcgatgat gatgatgtcg gcattgacgg
      361 agcaagcaga aaaaagtgag acaccagaaa tgttccgtaa gcagttgaaa atggtggcag
      421 agatcatcaa cgcttcccag tctgagatgc gtgcgctgct tcttcatctg cgtccagtca
      481 atttagaaga aaaaagttta aaacaaggca ttgagcagtt attgaaggaa ttgcagaata
      541 aaatccagat ttcgctaaaa tgggaggtag aagatgtaaa attaactagt tccattgagg
      601 atcacttgtt ccgaatcgtt caagaattgt tatcaaacac attaagacat gctaaggcta
      661 atgaattaga agtctatttg cataaaatag ataacaatct tttattacgt atcattgacg
      721 acgggacagg atttaatatg aatgaaacca aaacgggaag ttatggattg aacaatatca
      781 aagaacgagt agctggtatt ggtggaacag taaaaatcat tagttttaaa gggcaaggta
      841 cgagcgtgga gaccaaggtc cctttgatga aggaggcata gataaagatg ataaaagttt
      901 tattagtaga tgaccatgaa atggtacgct taggcgtctc ttcttattta tctatccaag
      961 aagacattga agtgattgga gaagctgaaa atggacgtca aggctatgaa aaggcgatgg
     1021 cacttcgacc ggatgtcatt ttaatggatc tagtcatgga agaaatggat ggcatcgaat
     1081 caacaaaagc aatcttaaaa gattggccaa aagccaaaat cattatcgtc acaagtttta
     1141 ttgatgatga aaaagtttat cctgcaattg aagcaggagc agcaggatat ttgttgaaga
     1201 cgtctacagc acatgaaata gctgatgcta taagggctac gcaacgcggc gagcgagtac
     1261 tagaacctga agtgacaaca aaaatgatgg aaaaaatgag tcggcgaaat gatccagtat
     1321 tgcatgaaga attaacgaat cgagaaaatg aaattttgat gctgatttct gaagggaaaa
     1381 gtaatcagga aatcgcggat gaattgttta tcacactgaa aacagtcaaa acgcatgtgt
     1441 cgaatatatt agctaagtta gaggtagaag accgaactca agcagctatc tatgcgttta
     1501 aacatggttt ggtgaaataa aaacgatgat aaagaggata atcaaaagct gagaaaataa
     1561 ctattatttt tcttggcttt tttacaataa tgatgcttgc ttttgttttt ggaaaggctt
     1621 tgttatactg agaaaagaag atactaaagg aggaaaatgg tgaaacaaaa ttttgcaatt
     1681 gtaggccttg gacgatttgg cggaagcatc tgccgtacac tgatcgaagc tggacaagaa
     1741 gtactggcta ttgacagtaa tgaagatcga gtcaatgaat atatgaatat agccacccat
     1801 gctgttgtgg caaatgcaca ggatgagatg acacttcgtt cattaggtat aagaaatttc
     1861 gatcatgtaa ttgtcgctat tggagaagat atccaagcca gcatcttagt tactctgatg
     1921 gtaaaggaaa tgggcgtacc gaatatttta gcaaaagccc aaaatgagta ccatgcccgt
     1981 gtactagaga agatcggagc agatcgtgtc gtacaccctg agcgagacat ggggatacgg
     2041 attgcacata acttagtatc aaagaatatt ctagactact tagag
//
LOCUS       DADGKS010000205         2076 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.213, whole genome shotgun sequence.
ACCESSION   DADGKS010000205 DADGKS010000000
VERSION     DADGKS010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2076
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.213"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(97..525)
                     /locus_tag="JXV47_003117"
     CDS             complement(97..525)
                     /locus_tag="JXV47_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489081.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            complement(553..1191)
                     /locus_tag="JXV47_003118"
     CDS             complement(553..1191)
                     /locus_tag="JXV47_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1489082.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(1195..1965)
                     /locus_tag="JXV47_003119"
     CDS             complement(1195..1965)
                     /locus_tag="JXV47_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HAX1489083.1"
                     /translation="MIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQE
                     ISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSTYWERNILSGEIYPPLK
                     IKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFS
                     FFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIER
                     EPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
BASE COUNT          648 a          399 c          297 g          732 t
ORIGIN      
        1 tatacaacta aaaatgaata tattaaaact accaaaaata acttttaacg ctgtttcatt
       61 atatgttttt tctattttat ataaactttt ggatacttaa taccaaccgg ttggattgta
      121 ccaacatgag aatgtgtcag ttctatttcc tgtcgcactt gcataggccc atactccttt
      181 tgttgcattt gctgatcgaa tagagtttcc aactttcgct tttgcaccgt gacgattata
      241 gacacgacta tagtggttag aatgacctgt ttttctcgta caagttgtat cactataata
      301 aacccatctt ccagagctat gattaattgc tgttctagaa atttcccggt ctactggtaa
      361 atttgactta ataatattac ctttagcatc aaaatgaatc tctcctggct ttaaagattt
      421 gtaatagatt tcaccgtgaa ctgaatttgc ttccacttca gatgacatag cgtttcctcc
      481 aacaaaacct atccctagtg cacaaataat aactgctttt ttcataaaac gacatccttt
      541 cctttttgat ttttaaagca tgatcttctt gtttcctatt ttggtcagat atggatcatg
      601 cgtgactacg ataactaacg taccttggga agcttgttgc gataagattt caactacttt
      661 atccttattt cttttatcca atgacccagt cggttcatcg gctaaaatga ttttgctatt
      721 cttcaataag actctcgcac aggcgattct ttgcttctca ccaccagata atgtgtagat
      781 aggcgtactt agcttcttgt ttatatttac ttttttcaat gcctcatact ttgctgttcg
      841 cttatctgaa acatttaaat tcgaaaactt caatccaata tctaaattaa aatcgattgt
      901 ttcatattca atcaacccaa aatcttgaaa aagaaaagat atggtatttc tttttatcaa
      961 gcgcttctct ctcccagtta attgtttcgt ctcttgatcg aacaaataga attgtcctga
     1021 actgaactga tcattcaatc ctaatatatt caataacgta cttttacctg ctccactttc
     1081 tccaacaaca gtcacaagat ccccagcatc cgcagtgaaa cgatccaaat gaagaatcgt
     1141 tttgtttcga atgatttttt tcgcaccttt tatcactatc aacggctcca attgttaacc
     1201 tccattcatc agcaataact gacttttctt ttctgtagac aaaataaaaa caactgaaag
     1261 aataaaatca atgaagctaa agaaaaaaat attaaaaaga tatttaggct ctctttctat
     1321 aagaaaaagg aagattacac ttgtcgttcc ccatttgatg aggttcatca tgaagaaatc
     1381 tttatacgtt tcaaagagcg aataaccact tgaacgaaag atagcgattt tccgacaatt
     1441 gtagacaaaa tatatgcata acatgacata gctcaacaag aagaaagaaa agaaagtgag
     1501 taaaaatatc tgtatcaagt aatgaaatga tctgcttaac actttgacag ctatctcttc
     1561 agtctgagta tacggaaatg ataactgcaa gttatcacgt aactgacttt cttcaatcag
     1621 ctcaaataac ctttctttcg acaaagagcc tatcttgatc tttaacggtg gatagatttc
     1681 tccgctgaga atatttcttt cccaatacgt actgtttttc aatgtcagta tttcaacaac
     1741 cggataatgt tcgatccagg ggatagaagg aataaatgta taaatgggtt gattgttttt
     1801 tataaataga aatttcggtt ctttttcact gatttcttga taatattctg ttatttgcgc
     1861 caggtcattt tttaaatctg tatgtctata tcgttcaggg atcaatataa cagggtgcgt
     1921 ttctttttcg gttatttgga tcaaccttcc agagacatca atcaaaggaa atttcttaag
     1981 ataattcaga tttattttta tccctctgcc aaactgttca ttttcttcat tcaagtaatc
     2041 tgatacattg actaatatac ttccgttttt attcaa
//
LOCUS       DADGKS010000206         2070 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.214, whole genome shotgun sequence.
ACCESSION   DADGKS010000206 DADGKS010000000
VERSION     DADGKS010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2070
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.214"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..549
                     /locus_tag="JXV47_003120"
     CDS             <1..549
                     /locus_tag="JXV47_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar nucleotide-binding protein"
                     /protein_id="HAX1489084.1"
                     /translation="DYVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYY
                     IIRTSWVFGIYGHNFVFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAP
                     FGIYHLSNENSCSWYEFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELG
                     FVIPTWQEALAQMLEAAKKMNK"
     gene            583..>2070
                     /locus_tag="JXV47_003121"
     CDS             583..>2070
                     /locus_tag="JXV47_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489085.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAF"
BASE COUNT          597 a          341 c          455 g          677 t
ORIGIN      
        1 gactatgttt tcgatggaaa aaacaaaaat gtagaatacg aagtagacga ccaaacgaat
       61 ccactaaatg aatatggtcg tacgaaatta ttaggcgaaa aagcagtaga agagatttta
      121 gaagactatt atatcatacg aacttcttgg gttttcggga tctatggaca caatttcgtc
      181 ttcacgatgc aacgcctagc ggaaacccgc gacaaactga ctgtagtaaa tgaccagttt
      241 gggcgaccaa cttggacacg tactttggca gaatttatgg tatatgtcat cgaagaaaaa
      301 gcaccatttg gtatttatca tttgtcgaac gaaaatagct gttcttggta tgaattcgca
      361 aaagaaatat tgaaagatac agatgtagaa gttgcacctg ttacgtcaga agaatttccg
      421 caaaaagcaa cacgtccgca gtattcagtc atgagcctga aaaagacaga agagttagga
      481 tttgtcatac caacttggca agaagcactt gcgcaaatgc tggaagctgc caaaaaaatg
      541 aataagtaat ttccttttat caaatagaat ttggagcatg atatggaaaa acaaacaaga
      601 agtgcacgac gaaaagaaaa gccaaaagcg aaccaggcag attcgaattt ggtgcttgac
      661 ctgtttctaa aactccgcta tcttattggc gttttagtca tcgtggtcat cgttactttt
      721 aatttaaacg gaagttcact tggtgtttgg gataaatatg tgtcgcaaag agacgatggg
      781 aaaaaaactg atgtgatttt tggacagaat cgggaagtgc ggtcagacga atggctggtg
      841 cagacacctt tttacctctc acaagctgaa gaggactttc cgttggtgaa cgaggattat
      901 tcattaaacg gacaaaacat gatcattgcg tataattctc ctgtaaagga tattacggtt
      961 atcggaaaac cattcaactg gggattcttt ttcctcggaa gagatcgagg actttccttt
     1021 tattgggcga tgaaattagt cgtcatggtc ttgcttggat tcgaagtact gatgatatta
     1081 acgaagagaa aaaaagctct atcgctaatc ggtgcatttg cgctgacatt ttctccagca
     1141 gtccagtggt ggttcatgca acatgtgggc gatttgattt tctttacttt gggactgatg
     1201 actgcttttt atcattattt ctacaatcat gataaaaaat ggctacgaac gttgatgatg
     1261 cttttggtgg ttattttcgg tattgggttt attttagtga tttacccagc ccatcaagtg
     1321 atgctggcgt acttgctgat tttttatttt gttggcctgc ttatttacta tagcaagaaa
     1381 gtttcatggg atctgttgga tgtagtgttg attggagggg cagttttatt tattggcgga
     1441 gtcatggttc atttctggct aacgtcaaaa gacgcattgt tagcttcttt gaatacctta
     1501 tatccaggaa aacgggtaag tactggagga aagtggacga ttggcgaatt tttttctttc
     1561 cttacaaatt ggaaaattcc ttttgaagat atcaactatt cgaataactc tgaagtggcc
     1621 ctgttctatc acttttttcc aactgtattc ctagcaagtc catttgtgtt atttggcaaa
     1681 aaagatagcg aacaaaagtt actgggacgt attttgatga ttttttgtct gttttctatc
     1741 ttttggatta ccgttgggtt gccaaaatgg ctagcagaaa tcactctgct gtcttatgtt
     1801 cctccattaa gagccatcct tacttttagt tttgcggctt gtttattatc gatctggttt
     1861 atcgcttata tttggagaga agatgttatt cctatttggt ataaattcat tttgttggca
     1921 gtaaatgcat ggtcttattt ctatgcgatt acgcattcga aaatggataa ttatttttcg
     1981 gattttgaaa ccatcgcagt tgctgtgttg ggaacagtga ttttagcttt tgcattattt
     2041 ggctggagac gcttgtttta cctcgctttt
//
LOCUS       DADGKS010000207         2040 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.215, whole genome shotgun sequence.
ACCESSION   DADGKS010000207 DADGKS010000000
VERSION     DADGKS010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2040
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.215"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..1389)
                     /locus_tag="JXV47_003122"
     CDS             complement(<1..1389)
                     /locus_tag="JXV47_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017434062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1489086.1"
                     /translation="MSNKEEAKSIINFVGGKENIAALTHCVTRLRFALRDDTKVDKAG
                     LENLEDVKGTFNANGQFQVVIGPKVADIYEEVISQSGLSGANKEDVKKVAAELNLNWF
                     QRAVKILGDVFVPILPAIVTAGLLMGLNNLLTNPGIFFEQSLIEVYPNIADVADMINL
                     IANTSFQFLPALITWSTVKYFKGNPLLGIVLGLVFVHPDLMNAWNYGQAVTTGDIPHW
                     TIFGLSISKIGLQAQVLPALVSGYVLAKTELFLKKRVPETIQLLVVAPVAILFTSVIT
                     FIIIAPITIAIGNTIVAGIVWLFQKVPFIGGFAYGIGLAPLVVTGMHHAFLPVHIQLM
                     ANGGDYIWPIGVMSSLAQGSAAIAMNFLIQNKKLKGVGLAAGLSAYMGITEPAMFGVN
                     LKYKFPFVVSILTSGIIGGFMASQHVIATSVGISGIPGFLSIPFEFWPIFFICMLASC
                     VVSFGATYLYGKN"
     gene            complement(1382..1936)
                     /locus_tag="JXV47_003123"
     CDS             complement(1382..1936)
                     /locus_tag="JXV47_003123"
                     /inference="COORDINATES: protein motif:HMM:NF025668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489087.1"
                     /translation="MDVLCGKINPAGKLTITIPRHLGQIPIYYNYFNTGRPYSSEKFN
                     TTKYLDVSNEPQFPFGYGLSYTTFSMSPISIKEKGKNCLKVTTTVSNKGSRDGYEVVQ
                     LYIGAQYGRYIRPTKDLVAYKKVFVKSGDSVTVSFELTNKDFKYYDEEFNEIIDDGAY
                     WIMVGNDSSQALTNKEEIEVRINE"
BASE COUNT          664 a          445 c          324 g          607 t
ORIGIN      
        1 atttttcccg taaaggtaag ttgctccaaa tgagacgaca caacttgcta gcatacaaat
       61 aaagaatatt ggccagaatt caaacggaat agacaagaaa cctggaattc cactgatacc
      121 aacagaagtt gcaatgacgt gttgtgacgc cataaatcct ccaattattc cagaggtcag
      181 aatggaaacc acgaatggga atttatactt tagattaacc ccgaacattg ctggctcagt
      241 gatacccata taagcagaca aaccggcagc cagtccaaca cctttcaact ttttattttg
      301 gattaagaaa ttcattgcaa tagcagcaga accttgtgcc aaacttgaca tgactccaat
      361 aggccaaata taatctccac cgttcgccat caattgaata tgaactggta aaaacgcatg
      421 atgcatccct gtcacgacta atggcgcaag accaatacca taagcaaatc cgccaataaa
      481 tggaactttt tggaataacc atacaatacc tgcgacaatc gtattaccaa tagcaattgt
      541 aatcggcgct ataataataa atgttataac actagtaaaa agaattgcaa ctggtgcaac
      601 aaccaacagt tggattgttt caggcacacg ctttttcaag aatagctctg ttttagctaa
      661 cacatagccg gaaactagag ctggcaatac ttgtgcttgt agtcctatct tagagatgga
      721 caatccaaag attgtccaat gtggaatatc tcccgtggtt actgcttgcc cgtaattcca
      781 ggcattcatc aaatctgggt gtacaaagac tagacctaac acaatcccaa gaagaggatt
      841 tcctttaaag tattttacag ttgaccatgt tattaacgca ggcagaaatt gaaaggaagt
      901 gtttgcgata agatttatca tatcagcgac atcagcaata ttaggatata cttcaatgag
      961 tgactgctca aaaaagattc ctgggtttgt taataaatta ttcagtccca tcagtaaacc
     1021 agctgtaacg atcgctggta aaatcggcac aaatacatca cccaatattt taactgcacg
     1081 ttgaaaccaa ttcaaattca actcagccgc tactttttta acgtcttctt tgtttgcccc
     1141 actcagccca gattggctta taacctcttc atagatatct gctactttag gaccgataac
     1201 aacttgaaac tgtccattag cattgaaggt acccttcaca tcttccaggt tttccaatcc
     1261 tgccttatca actttagtgt catctcgcaa ggcaaacctc agacgtgtca cacagtgagt
     1321 cagtgctgca atattctctt ttccaccaac aaagttaatg attgatttag cttcttcttt
     1381 attactcatt aattcttacc tctatttctt ctttattagt taatgcttga gatgaatcat
     1441 tgcctaccat gatccaataa gcaccatcat ctataatttc gttgaactct tcatcataat
     1501 acttaaaatc tttgtttgta agttcaaaag aaacagtcac actatcccct gacttaacaa
     1561 aaaccttctt gtaggctacc aagtcttttg ttggtcttat ataacgacca tattgagctc
     1621 caatatatag ttgaacaacc tcataaccat ctctacttcc tttatttgaa acggtagtag
     1681 tcaccttcaa acagttctta cccttctctt taatgctaat tggtgacata gaaaaagtgg
     1741 tataactcaa cccataccca aagggaaatt gtggttcatt ggatacatct aagtatttgg
     1801 tcgtattaaa cttttcactt gaatacggtc taccagtatt gaaataatta taataaatag
     1861 ggatttgtcc taaatgtctc ggaattgtta ttgtaagctt tccggctggg tttattttgc
     1921 cacaaaggac gtccaaaata gcattgccag cctctgctcc tagatgccaa gcctcaacta
     1981 atcccttaca tatagatttt taaattacac actagtttaa actaaaacaa acaaggaaaa
//
LOCUS       DADGKS010000208         2025 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.216, whole genome shotgun sequence.
ACCESSION   DADGKS010000208 DADGKS010000000
VERSION     DADGKS010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2025
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.216"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..153)
                     /locus_tag="JXV47_003124"
     CDS             complement(<1..153)
                     /locus_tag="JXV47_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAX1489088.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELTASAFDKW
                     VKQSKTS"
     gene            362..736
                     /locus_tag="JXV47_003125"
     CDS             362..736
                     /locus_tag="JXV47_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAX1489089.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(850..1479)
                     /locus_tag="JXV47_003126"
     CDS             complement(850..1479)
                     /locus_tag="JXV47_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAX1489090.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1613..1685)
                     /locus_tag="JXV47_003127"
     tRNA            complement(1613..1685)
                     /locus_tag="JXV47_003127"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1650..1652),aa:Thr,seq:ggt)
     gene            1899..1972
                     /locus_tag="JXV47_003128"
     tRNA            1899..1972
                     /locus_tag="JXV47_003128"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1933..1935,aa:Asn,seq:gtt)
BASE COUNT          677 a          309 c          350 g          689 t
ORIGIN      
        1 actcgtttta gattgcttta cccatttgtc aaatgctgaa gccgttagtt catattctcg
       61 aatgatttct acacgtggct ttccagctaa gtaaagattg acgatttgtt gcttgaattc
      121 ttgtgaaaaa gttcttcgtg ttctcttaga cataaaaatt cctcctggta tgttttcttc
      181 tagtctacac accttaattt ttctgtctag ttaattgtag cctatccaag tctacactct
      241 gagatgtaag aaatatcata agatatttct tacatctttt tgttttgagc aggactttag
      301 ataattttat taatatatgc tagcatgctt ttgtaagaaa aagaaagagg gcgtattagt
      361 tatgtatctt aaaattacgg aacaagcaca agaaagatta caaaaatata ttgatgaagg
      421 cgcaacagtt atattggatt tagatgatgg cgttggggaa tattctaaaa tgggtgtttg
      481 ctctttagat actagttttc gtttacttct tcttgataaa gaacagagaa aaaatgatta
      541 taaactccaa ttagatagtg atattgggga tgtttatata aaagattatt caaaaatgta
      601 catggatgaa catatgaccc tttctttaga tccacgtcta ggtgtattta ctcttgaaag
      661 cccaagtggt tctttagaca gtcatgttca attagtagat ctacgaccag aaaaattctc
      721 tggaataaaa caataacttt ctctctattg tccataaaac tagtctcaat caagctgtat
      781 tgaaaaaaca agacaacatt cttaccatgg taaataaaaa gacgacacat tttgtcgtct
      841 ttttttaaat taactatttt cgataaaaga tcgcatagct tgtgccatta tttctggctt
      901 ttctctattc aattcatgtt ttccgttttt aataaagagt agccggccat tcgttgaaag
      961 tttatataaa cgttttgctg ctggtttatt cgcatgatct ttggtaccgc ataaaatcaa
     1021 tttaggaagt cgtgatgtac gaagctgttt tttgcagtct aatgtttcaa gtgaacgaag
     1081 tagggtaagg gtttgttttt tagatagacc taatttttca aatatcttag aaggtacgca
     1141 gtaaaaataa atattctgga aagtaagcaa taagcgatta ggagactcaa attgtggagc
     1201 gactaaaaca acctttttta aatatggaga aggagttgca agatagttta aagcaataac
     1261 agcgcctaaa gataatccac ataaaataaa aggttccttt atctgattca attgtacttc
     1321 gatgtatttg gttaagtcgt ctaaagtagc agtgtctgtg ctgtttaaat gattgaacaa
     1381 tgaaagactt ttgcaagaat aactattggg tagataagag attacatctt tccatgattg
     1441 ttcgtcttgg cctagaccat gcaaaaaaac aattttcata ttgctctcct ttttatagtt
     1501 atcatataga ctttctttgt actattaaaa tataaacatt catttcttac gtcataaaat
     1561 aaaaaaacag cgcagacaca ttgttaaacc aacatgttgc actgtttaag gaagccactt
     1621 gccgggcttg aaccggcgac ctcttcctta ccatggaagc gctctaccag ctgagctaaa
     1681 gcggcattat cattaataca aataatagga taacgaatat taatgtattt gtcaacagaa
     1741 ttttttcgaa aaaatgtgtt tctctaatag gaaaacagat tttagaaaaa ataaaaataa
     1801 caaaaaatgc gaacggtttc tttgataata taataaaaaa attcaaaaaa agtattgcgt
     1861 tatttagaag aaattgatat tatattcatg tacttgattc cggcatagct cagttggtag
     1921 tagcgcatga ctgttaatca tgatgtcgta ggttcgagtc ctactgccgg agtaaataaa
     1981 gcttatgcaa agaaaaagaa atccaatcac ttgggtttct ttttc
//
LOCUS       DADGKS010000209         1995 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.217, whole genome shotgun sequence.
ACCESSION   DADGKS010000209 DADGKS010000000
VERSION     DADGKS010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1995
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.217"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            628..>1995
                     /locus_tag="JXV47_003129"
     CDS             628..>1995
                     /locus_tag="JXV47_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAX1489091.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQS"
BASE COUNT          610 a          363 c          406 g          616 t
ORIGIN      
        1 tatcaagagg tcttgagcct gccgtttaac tctgagccac aaggagcaat ttcaaaaaat
       61 agctccttat atttttcgtt tggttgggct tattaccgca gatgcaagct tttgaacacc
      121 gtttaccaag aggttgtaaa attagcgtcc tgacataatc taataccgag ggtcagctga
      181 ttgaacaccg tgtatcaaga ggtcttgagc ctgccgttta actctgagcc acaaggaaca
      241 atttcaaaaa acagcttctc atgttttata aatattgtga cttgtggccg aggagttggc
      301 aggagaacac cgtttaagga agaagttgtg aaaaagctgt cctgcatcaa gaaataagga
      361 gctgcgacaa gaattttgtc acagcctctt tttttgtacg aataccgaga aactggcttt
      421 tgaataccgt ggagtgaagc ggtcaccaca agacttttat ctcttcatta gtttaatcgc
      481 ttacatcgca gcggttttat gctgtgaaaa gtggacggaa taatctttag aaagaataaa
      541 aaaatcttaa gataacaact tttttaggaa attttcattt ttcaggagca aaataagaaa
      601 aaatgtgaat agagagaagt gatatacgtg acacaactta aaaaattgtg ccaaaatcgt
      661 ttagcaatcg ttttgacagc tgttttcttt ttctggctga agacgatcat tgcctactat
      721 gcagattttt cattaggtgt ggaaggtacg atccagtact ttatcttgtg gatcaaccca
      781 attgcgacta ccttattgtt ttttggcctt tctttgtata ttaaaaagcc aaagccagcg
      841 ttagctattc ttttgatcat tgatatttta aatacgcttt tgttgtactt gaatattatt
      901 ttttatcggg aattcacaga tttcattaca gtcaaatctg tattaggctt ttcgaaagtg
      961 tcgcaaggat tgtcaggaag ctccttttct ttgatgaagc cccatgatgt catctactgg
     1021 ctggatatcg ctgtgttcat tgggctactg gtttggttga aggtcaagaa aatacctatc
     1081 aaaagcaacc ctgtcggcaa accgatggct atcgctgtta cctgtctttc agggcttatt
     1141 ttttcaggaa atctagcgct gagcgaagcc aaccgtccac aattgctgca gcgaacattt
     1201 gaccgttcat atattgtcaa atatctagga atcgatgcgt atactattta tgacggaatc
     1261 aaaacaggaa tgactagcag tgttcgcgcg catgcaagca gtaatgggat tgatgaagtt
     1321 ttagattata caaagaaaca ttatgcagag ccaaatcccg aaacatttgg gatcgctaaa
     1381 gggaaaaatg tgatcgttct ccatttagaa agtttccagc agtttttgat taatatgaag
     1441 gtagacggac aagaagtcac accgttttta aatagtattt tccagaatca agcaacgatc
     1501 agctttgaca atttctttca tgaagtagga cagggaaaga caagtgatgc tgaaaatatg
     1561 ttggaaactg gcacatttgg tttacctcaa ggctcattat tcacagaact tgggtcagac
     1621 aatgtctttc aagccgcacc agcgatcctt ggacaaaagc aaggctatac aagcgctgtt
     1681 ttccatggga atgtagctag tttttggaat agagatcatg tatataaaaa cttaggttat
     1741 gacaatttct ttgatcgatc ttattttgat gaatccgacg aaacgttagg ttatgggata
     1801 ttagataaag atttattcag agaatctgcc caatatcttg agcatctaca acagccgttt
     1861 tacacgaaat ttctttccgt aaccaaccac acgccttatt atacggatga caagaatttc
     1921 gactttccat ctttgaatac tggcaatagc acagtagata attatgttcg aacggcccat
     1981 tatctggatc aatca
//
LOCUS       DADGKS010000210         1918 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.218, whole genome shotgun sequence.
ACCESSION   DADGKS010000210 DADGKS010000000
VERSION     DADGKS010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1918
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.218"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            158..484
                     /locus_tag="JXV47_003130"
     CDS             158..484
                     /locus_tag="JXV47_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489092.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(601..945)
                     /locus_tag="JXV47_003131"
     CDS             complement(601..945)
                     /locus_tag="JXV47_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489093.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(1021..>1918)
                     /locus_tag="JXV47_003132"
     CDS             complement(1021..>1918)
                     /locus_tag="JXV47_003132"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HAX1489094.1"
                     /translation="GIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQLL
                     QQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVPI
                     IETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIEK
                     ELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRHN
                     TKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHARG
                     PMGLNELTSTKYIIYGDGQIRE"
BASE COUNT          605 a          362 c          404 g          547 t
ORIGIN      
        1 atgattgagg agttggcaga agaacatcat ttattcggaa aaaggggatg tgacacgatt
       61 tttgtcacat tccctttttt tctcaaaata atgaaactgg aaaattttca gtaggtaagc
      121 taaaattcat ttaagaaaaa gaatgggggg ataatagatg ctggaagaat attttcagga
      181 agtcgggttg acactcgttg aattacccat tgaattttca gatgatcggt tgatttatcg
      241 tggctatatc aaagaattgc caataatcaa tgcggaaggt gaaactagaa aagcgatgca
      301 gcaaaaaata gctggtatgt atcaggtgta tcgggaacag ctactggctg aatcagcgga
      361 agaagaaaaa gaaaaaacga tgaacttgtc catggatgag ctgcttcgtt attatgatgg
      421 cgaaacattt gacggatttt cgcttcttaa cgaagaggaa acagatttac caggcagctg
      481 gtaggcgaac gccgtttata tggaaaaaga ggctgtgaca aaatctttgt cacagcctct
      541 aaaaagtccg gcagtttttt gccgatcttc aaggcactct acttatcgta cggatatttt
      601 ttagcggaaa gtccgattca agtggttttt attcagctga tatttataag ataagtgaaa
      661 aatcccagca atcagtagcg taatcgtata agcgattgaa tgatcgaaaa aagaatagta
      721 attgattgtc gctaataagc ataatgcaac catgtaacta atgtgcaagc gtgtaaccag
      781 ccctttttgc ccgattttgt caaaatactg cgaccatttt tcccgttgac tccctatgct
      841 tcgttttttg aattgaaaga aaagggataa aataccgact cccagaaaag cagcgatatt
      901 cagagaaata aggtaaataa aaaaaatcat taaaatttca aacatattga cacctttcta
      961 gttggataga acctttacag aaaaaaggca aaaggcggga ataatgtttc acacgaaaca
     1021 ttattcgcgg atttgtccat cgccataaat gatatatttt gtggaagtta attcatttaa
     1081 ccccattgga ccacgggcat gcaacttttg agtagagata ccaatctctg caccaaaacc
     1141 aaataccgat ccgtctgtaa aacgagtgga ggcattgaca tagacagccg ccgcgtccac
     1201 ttcatttaag aaacgttgac tagccgcata actatctgtc acgatcgttt ctgaatgttt
     1261 agtattatgc cgattgatat gtgcaattgc ttcatccaaa gaatcgacca ctttgacagc
     1321 aaggatataa tctagatatt cagtatccca atctgtgtct tctgctaaag cagccgtctc
     1381 tagatattct aacgcacgag catccgcacg taaagagacc ccgtgttcta ccagttcttt
     1441 ttcaatagct ggcaagaaaa aaggtgcgat ctcagaatgg atcagcaatg tttctgccgc
     1501 gttacagaca gatggacggg aagcttttgc attgacgatg atgttcactg ccatagataa
     1561 ctgtgcttct ttatcgatat atacgtgatt atttcctgta cctgtttcaa tgataggtac
     1621 cgttgcctgt tctttgactc gttggattaa ttttgctccg cctcgaggaa tcagcacatc
     1681 taagtattct gtcaatcgca tcaactgtcc tgcagtttca tgagaagtat catcgacaaa
     1741 ctggatggca taaggagatt cgccagcact gaccagtact tgctgcaata attggactaa
     1801 taattgattc gagaagaatg cttctttgcc accgcgaagg ataacggcat tccctgattt
     1861 gaatgctaga ctagctgcat ctgtcgtgac atttggacga gattcgtaaa tgatgccg
//
LOCUS       DADGKS010000211         1817 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.219, whole genome shotgun sequence.
ACCESSION   DADGKS010000211 DADGKS010000000
VERSION     DADGKS010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1817
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.219"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..562
                     /locus_tag="JXV47_003133"
     CDS             <1..562
                     /locus_tag="JXV47_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HAX1489095.1"
                     /translation="DTGGYQTGDTAYLYSIVEMVPSEDPDYVLYLTMKHPKTYDRMAL
                     AKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYRNLEADVAAADAQKSGLQPVVIG
                     NGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVTGWSKADIMKLGKILGIEVSFDG
                     DGYCVKQELAPYEKITEDKLSFTLEE"
     gene            588..1550
                     /locus_tag="JXV47_003134"
     CDS             588..1550
                     /locus_tag="JXV47_003134"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HAX1489096.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            1564..>1817
                     /gene="murD"
                     /locus_tag="JXV47_003135"
     CDS             1564..>1817
                     /gene="murD"
                     /locus_tag="JXV47_003135"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172514.1"
                     /note="UDP-N-acetylmuramoylalanine--D-glutamate ligase;
                     involved in peptidoglycan biosynthesis; cytoplasmic;
                     catalyzes the addition of glutamate to the nucleotide
                     precursor UDP-N-acetylmuramoyl-L-alanine during cell wall
                     formation; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HAX1489097.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPY"
BASE COUNT          571 a          292 c          418 g          536 t
ORIGIN      
        1 tgatacaggg ggatatcaaa caggagatac agcctacctg tattcgattg tggagatggt
       61 tccttctgaa gatccagact atgtcttgta tctaacaatg aaacacccta agacatatga
      121 tcgaatggca ttggctaaaa tcgcaaatcc attgatgaaa cgggcaatgg attttaaaga
      181 aactgaagaa gattcagata cagaaacaaa aacagaaaaa gtatccgtag ccgattatcg
      241 taatcttgaa gcggacgttg cagcagctga tgctcaaaaa agtggactgc aacctgtagt
      301 gatcggtaat ggtaaaaaag tacaaaaaca atctactgcc aacggtgatc agttgatctc
      361 tggagaaaaa ctgatcctat atactggtgg tgataagctg atgcctgacg taacaggatg
      421 gtcaaaagca gatatcatga agctggggaa aatcctcggt attgaagtta gttttgatgg
      481 agatggttat tgtgtcaaac aagaacttgc tccatatgaa aaaatcactg aagacaaact
      541 tagttttact ttagaagaat aagaagagaa ataggagaga aaagagcatg gaatggacac
      601 aagcattgat tcccattgtc agcagttgtg caatgacaat tgccgcaatg ccgctattta
      661 ttggttattt tcaaatgaaa aagcaaggtc aggcgattcg tgaggaggga ccaaagtggc
      721 acaatagcaa agccggaact cctacaatgg gcggcttagt gtttctgatc ggctctattt
      781 tgacaggaat ttgggttgga gcttggcaaa aacagctaac tcctactctt ttcatcttgc
      841 tttttgtatt agcgttatac ggagtaatcg gctttcttga tgattttata aaaatattca
      901 agaaaagaaa catgggactg aactcgaagc agaaattgat tggacagatt ctagggggaa
      961 tcatctttta tcttgtttac cgttctgaag gttatccagg tgtattgaat ttcttcggac
     1021 tagatctacc tttaggaatc atttatggta ttttcgctct cttctggctt gttggatttt
     1081 caaatgcagt aaatctgaca gatggcatcg atggattagt tgctggctta ggaagtatct
     1141 cttttgcagc ttacggtcta attgcttggc atcagcatca gtatgatgta ttaatcattt
     1201 gcttaagtgt tttaggaggt ttactgggtt tcttcgtcta caacagaaaa cctgccaaga
     1261 tttttatggg agatgtcggt tcattagcgt tgggcggact tttagcggca atttctataa
     1321 tgctaaacca agaatggaca ttgcttttga ttggtttgat ctatgttatg gaaacagcaa
     1381 gtgtgatgct tcaagttact tcctttaagc ttacaggaaa acgaattttt aaaatgtctc
     1441 caattcatca tcactttgaa atgtgcggat ggtcggagtg gaagattgat acagtttttt
     1501 ggttgatcag cattgtgact tcgttgatca cattatggat cgtttggtag gagatgacgg
     1561 gaaatgaaaa aaatatcaac atatgaaaat aagaaagtgc ttgtcttagg actcgcaaaa
     1621 agcggagtaa gtgcggccaa attattacat gaattgggcg cacttgtcac cgttaatgat
     1681 ggaaaacctt ttgacgaaaa tccggaagca caagagctgc tttctttagg gataaaagta
     1741 ataacaggta gtcatccaat cgaattgttg gatgaagaat tttcattgat ggtcaaaaat
     1801 ccagggattc cctacag
//
LOCUS       DADGKS010000212         1799 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.220, whole genome shotgun sequence.
ACCESSION   DADGKS010000212 DADGKS010000000
VERSION     DADGKS010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1799
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.220"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..945
                     /locus_tag="JXV47_003136"
     CDS             <1..945
                     /locus_tag="JXV47_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAX1489098.1"
                     /translation="INDEYNLAPNQGDSRLAIPNKIILHETGIDAPARNVAANMKNNY
                     NGSNSYTTDVIGDGGIVYRVGEQGYVSWGAGNANPYAPVQIELQRTYDKALFEKNYRA
                     YIEYTRDSAKKYGIPLTLDQGTSLFTKGIISHLWVTNYVWGNHTDPYGYLSQMGVSKE
                     KLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNHAHIDQFGEIENANLHV
                     AGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTSGNVGYHVSFNMRNF
                     PSKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
     gene            1135..1208
                     /locus_tag="JXV47_003137"
     tRNA            1135..1208
                     /locus_tag="JXV47_003137"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1169..1171,aa:Ile,seq:cat)
BASE COUNT          597 a          307 c          342 g          553 t
ORIGIN      
        1 attaatgacg agtataattt agcgccgaat caaggagact ccagattagc aattcctaac
       61 aaaattattt tgcacgaaac tggaatagat gcaccagcaa gaaacgtagc cgccaacatg
      121 aaaaataatt ataacggaag caattcttat actacagatg ttattggtga cggtgggatt
      181 gtttaccgtg tgggtgagca aggatatgtt tcgtggggag ctggtaacgc taatccttat
      241 gcgcctgtac agattgaatt acagcgcaca tatgataaag cattgtttga aaaaaactat
      301 cgagcttata ttgaatatac aagagatagt gcaaaaaaat atggaattcc attgactctt
      361 gatcaaggaa cttctttatt tacaaaagga atcatttctc atttgtgggt gacaaattat
      421 gtttggggga accacacaga tccatatggt tacttatcgc aaatgggagt tagcaaagaa
      481 aagcttgctt atgatttagc tcatggattt accgatgaaa atccaacaac ttctgaaaac
      541 aagcctgtca ttgatccaac acgagctggt gcagctaatc ctacgctgac agatggaaca
      601 aatcacgccc acattgatca gtttggggaa atcgaaaacg caaacttgca tgtggctgga
      661 tggcacattg ctaactataa atacgagtat attttcatta tggactacaa tactgggaaa
      721 gaattagctc gagtaagagc tgatggaatt tatagaccag atgtaaacca agcttataat
      781 acttctggaa atgttggtta tcatgtatct ttcaatatgc gtaattttcc tagtaagaaa
      841 gtctatgtaa tgatgcgggc aacgaatgat ccagagggaa acactaaagg cggtgcgcaa
      901 gatttccatg acaaacgttg gtatttaaat attcctaaac gataaaaata gctcctcgtt
      961 gaggagcagt acataactat attgacaact ataaaaatta ttcgataaaa tagtgatgtt
     1021 atcgcatatc ttcactatca cccataaata gtcacactcc aagctatgcg ataacaggtt
     1081 tgttgccaca cattctactg gttgattgtt tatggcttta tgtggcaaca accagtaccc
     1141 ttagctcagt tggtcagagc agacggctca taaccgtccg gtcgtaggtt cgagtcctac
     1201 agggtacatt aacgtagcca tttgaatcgt tctgtgttag aatttttttg aagagtatta
     1261 tacaagctaa agcttttctt cattgccact caaatgagtg gcttttttat gtatcctttt
     1321 atggattaat gaaaggatgt ttcacatagt tatacttctg tatatttgaa aagttttact
     1381 ttgattttta aatagaaaga catttgggtt aaattgtgag ataataataa agaagagttt
     1441 aaagcgcacc ccaaaccact tccccataag tgtgttacgc tttaaactct tttatatttg
     1501 aagccattaa aaagcatacc atatttttga aaaaaagtga gaaaaaaggc ttacaattgg
     1561 agtggtagtt aattagtgac ttatttttga ttttatagca ctgatactat aaaatataga
     1621 tatcatcata ttacacaatc ttaatactaa cttaaaaaat atctcctttc acaagtatgg
     1681 tgataaaatt cgttccgggc taccttttta ggtagcctac tttaatcttt atacctttct
     1741 ggatcaacga aagtatactt tatatagtca taacgccgat gatcgctacg tgcgtccgg
//
LOCUS       DADGKS010000213         1758 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.221, whole genome shotgun sequence.
ACCESSION   DADGKS010000213 DADGKS010000000
VERSION     DADGKS010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1758
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.221"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..347
                     /locus_tag="JXV47_003138"
     CDS             <1..347
                     /locus_tag="JXV47_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HAX1489099.1"
                     /translation="TSFYSPRHHQESNYELFSAGWAQEVYEKDMEELTNAEFVLAILD
                     FEHQTIDPGTAYELGVATMLKKPMIIVQEETVPTNLMITQSLHTYLKSDQAVREYDFE
                     KLPVETYVGEYL"
     gene            363..1064
                     /locus_tag="JXV47_003139"
     CDS             363..1064
                     /locus_tag="JXV47_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAX1489100.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDTFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(1562..>1758)
                     /locus_tag="JXV47_003140"
     CDS             complement(1562..>1758)
                     /locus_tag="JXV47_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489101.1"
                     /translation="TYQTQGADSSESSEEKTVLTDIKITTKDDEYIISGKENKKEATV
                     TFTKIGNYRLKDKDGNIYSL"
BASE COUNT          572 a          282 c          351 g          553 t
ORIGIN      
        1 tcacaagttt ctactctcca cgtcatcacc aagaaagcaa ttatgaacta ttcagcgctg
       61 gatgggcgca ggaagtatac gaaaaagata tggaagagtt gacaaatgca gaatttgttt
      121 tggctatcct tgactttgag catcaaacaa tcgatccagg aacggcttac gaattaggtg
      181 tggcaactat gttgaaaaaa ccgatgatca tcgtacaaga agagacggta cctacgaact
      241 tgatgattac acaaagtctt cacacgtatt taaaatcaga ccaagctgta cgtgaatatg
      301 attttgaaaa attgcctgtt gaaacttacg taggcgagta cttatagaag aggaagggtt
      361 gtatgtcagt gattttgatt tcaggaacga ttggtgcagg taagagcagt ttgacggata
      421 tgcttgcaaa agagattgat tctaaaccat tttatgaaaa tgtcgaagat aacgaagtat
      481 tgccgctttt ttattcaaat cctgagcagt acgcattttt attgcaaatc ttctttttga
      541 ataagcgatt tttagcaatg aaaaatgctt tagtgaacga tgacaatgtg ctagaccgct
      601 ccatctacga agatagtctg ttgttccatc taaatgctga tttaggtcgg gtaacggata
      661 tcgaagtaca gcagtacgat agcttattag atacgatgct aaacgagtta gatgatgttg
      721 ctccaaaaaa acgtcctgat ttgatggtcc atatcaaagt ttctttggac acgatgctag
      781 aacgtatcaa aaaacgcggg cgtgactatg aacagctaga aagcgatgaa acgttataca
      841 cctattacga aacactgaac acccgctata atcaatggta tgaggatttt gatgtatgtc
      901 ctaaaataca agtggatggg gatacattcg attttgtaga aaatccagaa gatgcaaaaa
      961 aggtgattcg tcagatccaa gaaaaattag ctgaattgga aggaaagcct gctggaaaat
     1021 attttacaga taatcagcat gcgaaaggtc aagaattagg ctaaaagtaa aaaaccaaac
     1081 gacgggaaag aaaaattact acgtgatgta gaataagtct ttctatcgtt tggttatttt
     1141 atattcaaag atgtgaaata aataaaacgt tactctttga tttgtgaact gaaatgatcc
     1201 actgtttgtt ttactgattc cagtttttga agcttgatca aaggaagaag ctgagtttga
     1261 agttcataaa aatcagccat agtgagtttt gcttgatttt gcttatcttc ttttgctttt
     1321 tacataattt ttgacaggat aagattcaaa cgatttaaaa gaatctttga ctagtttgtg
     1381 gcaattgtcg catatactca aacttccttg atcattaaat tctgtatgga tatttttgtt
     1441 gttattacat gtacaataat caggactatc gatcatccat ttcgtctcct ttacagtcat
     1501 cttgcttctt tactatagca gaaaagaagg ggagaaacaa aagaagatcc aacagatggc
     1561 actatagact gtagatgttg ccatccttat ccttcaaacg gtaattaccg attttggtaa
     1621 atgtgactgt tgcttctttt ttattttctt ttcctgaaat aatatattcg tcatctttgg
     1681 tagtaatctt gatatctgtc agcactgttt tttcttcaga tgattcagaa gaatcagctc
     1741 cttgtgtctg atacgtgc
//
LOCUS       DADGKS010000214         1752 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.222, whole genome shotgun sequence.
ACCESSION   DADGKS010000214 DADGKS010000000
VERSION     DADGKS010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1752
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.222"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            383..1633
                     /locus_tag="JXV47_003141"
     CDS             383..1633
                     /locus_tag="JXV47_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAX1489102.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     ETILEFNNSYHFDQIVIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFS
                     RMFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQH
                     FLENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGK
                     GRFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQ
                     VIVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQ
                     SQNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARK
                     FTRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          578 a          335 c          309 g          530 t
ORIGIN      
        1 ttgtctaata gtttttattc aaaatgtttc tagattataa aatttattga ataacacatt
       61 cctaacggaa tttgtttcga tattgtgtga tttctcagag tacaatggat gtatggaaag
      121 gatccaacgg gaatttgcta tttcctcctg tagcgtttgt ctaccctgtt tagtctgtta
      181 cccgaaccac tgttatcact accaactcat tagctgtttc gataatggac tagactttca
      241 aatagtagtt tggaaggcag cttctagctc ttttatcacc gtattctatt aggcgaggtt
      301 gtggctatac agtgagtttc tgggaaatcc cacagtatcg aagcattttc caaaatttat
      361 atcgaaagga ggtccttctt ccatgaaatt atttgtcggt attgacgtta gctctgaaaa
      421 actagatgtt tgttttttaa cagacgacaa tcaattgtct atcttatctg aaatctctgt
      481 tgccaatgac atcgaaggtg cttcattcat acgagaaaca attcttgaat tcaataacag
      541 ctaccacttt gatcaaattg tgattggcat ggagtcaacg tccatgtaca gcttccatcc
      601 ttccatgttt tttcatgaag atgagaaact aaagaagctc aacacacttg taacgattga
      661 aaatcctttt cgggtgaaac aatttagtcg catgtttgat gagaataaaa ctgatcgaaa
      721 cgatgcatta agaatcgctg atttcttgcg tattcaacga ttcacaactt cccctatcaa
      781 agaagagaaa tacatggcct tacagcgttt aacacgtact cgctatcaac ttattaagca
      841 attgattcgt acaaagcaac attttcttga aaatctaacg tacaaatgta atacgcttgc
      901 tcgagaaatg cgagacgaat cgacgagtct ttttagtgca accctcattt cactcatgac
      961 ggaagatttc acattggatg aacttgctga gcttccttta gaagctttct gtgatttact
     1021 tcaagaaaaa ggaaaaggcc gtttcaagca accagaaaaa atcgctaaag caattcaacg
     1081 tgcaattacc atgagttacc gcctaggtgc tcttgcacaa gaatcaatta atgttgtttt
     1141 aagtgttctc gtacgagaaa tacgagcact tgaaaaaaat atcaaagaat tagataaagc
     1201 catcgaacaa gtaattgttg tcattccaga atatcaatgc ttaaccagta ttccaggcgt
     1261 tggtaaagtc tatgctgccg gtttaatcgc tgaaattggt caaatcgaaa gatttgaaga
     1321 tcagacaaaa ttggcaaaat acgctggatt aagttggaaa gtgaaccaat ctggaaacta
     1381 tcagtcgcaa aatacacctc tgacaaaaca aggaaatcga tattttagat actacttagt
     1441 tgaagctgcc aactctgtaa aaaattatct tcctgaatac aaagcttttt atcaaagtaa
     1501 atataaggag gttccaaagc atcaacacaa acgtgcactc gtcctaaccg caagaaaatt
     1561 tacgcgtctg gtggatacgc tactacgtaa acaccaactc tatacgccac caaggagtgt
     1621 gatagagaaa taacaatccg ttattgacgc aaatccttga atcaacccga aaaaaatttg
     1681 attttgatcg ggtctagttt cgtgcgcttc aaaacatatt actcaataaa gaaaatctta
     1741 aatttcatct tg
//
LOCUS       DADGKS010000215         1738 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.223, whole genome shotgun sequence.
ACCESSION   DADGKS010000215 DADGKS010000000
VERSION     DADGKS010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.223"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..1732
                     /locus_tag="JXV47_003142"
     CDS             <1..1732
                     /locus_tag="JXV47_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HAX1489103.1"
                     /translation="RMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVETITK
                     QFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISNFTQ
                     LAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSGYLT
                     RRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPETNE
                     LIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVEVGE
                     AVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVITEVT
                     GDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSIDPK
                     QLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTDILP
                     GTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRVLTD
                     AAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEAQMA
                     AEDAMNNQTK"
BASE COUNT          556 a          357 c          392 g          433 t
ORIGIN      
        1 ccgtatgaaa gacttagggt acaaacattc gacacatgcc ggtatcacag tagggatcgc
       61 tgacatcagt gtactgaatg aaaaacaaga aatcattgaa aatgcccata aacaagttga
      121 aactattaca aaacaattcc gtcgtggtct gatcacagat gacgaacgtt atgaacgtgt
      181 cattgctgtt tggaatgctg caaaagacag catccaacaa aaactgatgg aaggtttgga
      241 agcgaaaaat ccaatcttca tgatgtctga ttctggagct cgtggtaaca tttccaactt
      301 tacacagctt gccggaatgc gtggtttgat ggccgctcct aatggtcgaa tcatggaatt
      361 gccaatcatt tcgaacttcc gtgaaggact atccgtcttg gaaatgttta tctcaactca
      421 cggggctcgt aaagggatga ccgatacagc cttgaagact gccgattcag gttacttgac
      481 tcgtcgtctg gttgacgtgg cccaagatgt aatcatccgt gaagaagatt gcggtactga
      541 ccgaggtctt gaaatccaag ccatccgcga gggaaatgaa atcatcgaat cattagaaga
      601 tcgtttagtg ggacgttaca cccgtaaaga agtacgtcat cctgaaacaa atgaattgat
      661 cattgcagga aaccaattga tttccgaaga catcgcaaaa caaatcgttg atgcaggtgt
      721 cgaaacagtg acaatccgtt ctgtcttcac atgtaataca aaacatggtg tctgcaaaca
      781 ttgttacgga cgcaaccttg caactggctc tgacgttgaa gtcggagaag cagttggtac
      841 gatcgccgct caatcaatcg gtgaacctgg tactcagttg acgatgcgta cattccatac
      901 aggtggggtt gccggagacg atatcactca aggtcttcct cgtgtccaag aaatctttga
      961 agcacgtaat ccgaaagggc aagcagtgat cacagaagta acaggggatg tcatcgatat
     1021 ctcagaagat cctgcaacac gtaccaaaga agtaacaatc aaaggaaaaa cagatacacg
     1081 tacgtatact gttccttata cagcacgtat gaaagtagca gaaggcgata tgatccaccg
     1141 tggtgcacca ttgacagaag gatcaatcga tccaaaacaa ttgttgcaag ttcgcgatgt
     1201 attatctgtt gaaaactact tgcttcgtga agtacaacgt gtttaccgta tgcaaggggt
     1261 agaaatcggc gacaagcata tcgaagtaat ggttcgtcaa atgctgcgta aagttcgtgt
     1321 aatggatcca ggtgatacag atatcttacc aggtacatta ttagacatcg cagactttaa
     1381 agatcaaaac tacaatacgc tagtctcagg aggcgttcct gcaacttctc gacctgtctt
     1441 actaggtatc acaaaagcat cattagaaac aaatagtttc ttatctgctg catcattcca
     1501 agaaacaact cgtgtcttga cggatgctgc gatccgcggt aagaaagatc ctcttcttgg
     1561 tttgaaagaa aatgttatta taggtaagat catcccagct ggtactggta tgcaacgtta
     1621 tcgtgacatg gaaccaaaag aagtcggtgt agcaagcgaa aatgtctaca gtatttcaga
     1681 tattgaagcg caaatggctg cagaagacgc aatgaacaat caaacaaaat agatattt
//
LOCUS       DADGKS010000216         1721 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.224, whole genome shotgun sequence.
ACCESSION   DADGKS010000216 DADGKS010000000
VERSION     DADGKS010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1721
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.224"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..1198
                     /locus_tag="JXV47_003143"
     CDS             <1..1198
                     /locus_tag="JXV47_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HAX1489104.1"
                     /translation="LFIKNSTDIPHMYRYYVLFLLNSVLSYFFTYKRSLAIADQKNYL
                     VAINDFAFLFFMNIVQVIALYFYSNFTLFLIVQILFTLFSNINISRTVDKRYSYLKEK
                     DVVSLDKQTKDEVKKNVIGNMSSKIGGVIVMGTDNILISTFVNLTAVGIYSNYSLIVT
                     SVQNLCKQITNSITASVGNFAVSNKKKDSFELFKKHFFINHSLIFFSSILLLTLMNPF
                     ISLWVGAKYMLPMSTTILIVLNYSVQVYRNTSFVFIESFGLYWSQRKKPIIEAGVNLL
                     LSLLLLIVFDMGINGVLIGTIGSSLGFVIWYEAFIIYKTVFEKRFIHFFLTFWRSFIE
                     LIISAIVVFLLNEYLANGGSTFLQFITKTLITIVTTSILYLLLYFRREEFTFIKKILF
                     RYILKK"
     gene            1222..>1721
                     /locus_tag="JXV47_003144"
     CDS             1222..>1721
                     /locus_tag="JXV47_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAX1489105.1"
                     /translation="MKIAILSPAFSMGGASIVASKIAKGLIDSGHEVFFVSYLESEKP
                     QVESKYYDLYEKKIFLFKNFSRFHKILEYRLFGGFVPSRYIKKEKEQLKKVLKKEKPD
                     VIIFNTFIPSVLFSEFLKYEFPTVKLITWMHSDPDYSLNHIAKFYKKEYRKSFERVDS
                     IVCLSQ"
BASE COUNT          601 a          213 c          256 g          651 t
ORIGIN      
        1 tctatttatt aaaaatagca cagacatacc acatatgtat cgatattatg tattattttt
       61 attaaattca gttcttagtt attttttcac gtataaaaga tcacttgcaa tagcagatca
      121 aaaaaattat ctggttgcga ttaatgattt tgccttttta ttctttatga acattgtaca
      181 agtaattgct ttgtactttt attctaattt tactctattt ctaatagtgc agattttgtt
      241 tactctattt tctaatataa atatttccag aacagttgac aagagatatt catatttaaa
      301 agagaaagat gtagtttctc tagataagca aacaaaagat gaagtaaaga aaaatgtcat
      361 aggtaatatg tcctcaaaaa taggcggggt tattgtaatg gggacagata atatattaat
      421 ttctacattt gttaatttaa cagctgtagg aatttattct aactattcat tgattgtcac
      481 aagtgtgcaa aatttatgta agcaaattac taattctatc acggcaagtg taggaaattt
      541 tgctgtatca aataaaaaaa aggattcatt tgagctattt aaaaaacatt tttttatcaa
      601 ccactcacta atcttttttt cttctatatt gttattgact ttaatgaatc ccttcattag
      661 cttgtgggta ggagccaaat acatgctacc tatgtcaacg actattttaa ttgttttaaa
      721 ttatagtgta caggtttata gaaatacatc cttcgttttt atagagtcat ttggtttata
      781 ttggtctcaa cggaaaaagc ctataattga agcaggtgta aacttgttat tatctttgct
      841 tttgttaata gtttttgata tgggaatcaa tggagtactt atagggacta tcggatcgtc
      901 tctaggattt gtgatttggt atgaagcatt tatcatatat aaaacggtat ttgagaaacg
      961 ttttattcat ttctttttaa ctttctggcg aagttttata gaattaataa tttcggcaat
     1021 agtcgttttt ctattaaatg aatatttagc aaatggaggc agtacgttcc ttcaatttat
     1081 aactaaaacc ttaataacta tagtaacaac atcgatatta tatttgttat tatattttag
     1141 aagagaagaa tttacattta tcaaaaaaat tctttttagg tatattttaa aaaaatagct
     1201 ttctataaag gagtgtttta tttgaaaata gctatactat ctccagcttt ctcaatggga
     1261 ggagctagta tcgtggcctc aaaaattgca aaaggattaa tagatagtgg ccatgaagtt
     1321 ttttttgttt cttacttaga aagtgaaaaa ccacaagtag aatctaagta ttatgattta
     1381 tacgaaaaaa aaattttttt atttaaaaat ttttctcgat ttcataagat attagagtat
     1441 agattgtttg gaggctttgt tcctagtaga tatataaaaa aagaaaaaga acaactaaaa
     1501 aaagttctaa agaaagaaaa acctgatgtc atcatattca atacttttat acctagtgta
     1561 ctattctccg aattcctaaa gtatgaattt ccaacagtga aattaattac ttggatgcac
     1621 tctgatcctg attacagctt aaatcatatt gctaaatttt ataaaaaaga atatagaaaa
     1681 agttttgaac gcgtggattc cattgtttgt ctttcgcaag a
//
LOCUS       DADGKS010000217         1718 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.225, whole genome shotgun sequence.
ACCESSION   DADGKS010000217 DADGKS010000000
VERSION     DADGKS010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1718
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.225"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>1718
                     /locus_tag="JXV47_003145"
     CDS             <1..>1718
                     /locus_tag="JXV47_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAX1489106.1"
                     /translation="ILDFQTARHQNGIAVKLNGKYPYDDGIESSWERKKRLLKKGINY
                     ARTHGVKKAIRRVKLELKPGSIDYAEWISRHEKPDLKEQRKEVQGFAYRPLISILMPV
                     YNVEIKWLEKCIDSVLDQTYDHWELCISDDASTDPAIRKCLESYQAKDDRIKVVFRQE
                     NGHISLATNSALEMAEGEFIALLDNDDELPPFALYEVAKVLNVHPELDLIYSDEDKID
                     ADGNRFDPHFKADWSPDTLMGNNYISHLGVYRTSIVKELGGFRKGYEGSQDYDLVLRV
                     TEQIPAEHIYHIDRVLYHWRTIPGSTASNGEAKSYIYDSGVKALTDALSRRNIKGSVH
                     PGRISGFYEITYDVLQEDLVSVIIPTKNGYEDLKTCVDSIIEKTSYPNYEIIIADNGS
                     TDPKMQELFAEYKHQLKDRFIVELIDIPFNYSRINNLAAEKANGKYFLFLNNDTEVIE
                     PDWMTAMVSYAQFDRIGCVGAKLFYPDDTTQHAGVLLGIGGVAGHALNNYDRTHCGYF
                     GRLVIDVNYLAVTAACMMVKAADFNAVNGFDEILEVAFNDVDLCLKVYELGRYNVYAH
                     QAELYH"
BASE COUNT          570 a          303 c          371 g          474 t
ORIGIN      
        1 atcttagact tccaaacagc aagacatcaa aatggcatag ctgtgaaatt aaacggtaaa
       61 tatccttatg atgacggcat tgaatcttca tgggaaagaa aaaaaagatt actgaaaaaa
      121 gggataaatt atgcaaggac tcatggcgta aaaaaagcaa tccgccgggt caaactggaa
      181 ttgaaaccag gatcgatcga ctatgcagag tggatcagtc gtcatgagaa acctgatctg
      241 aaagagcaaa ggaaagaagt acaaggattt gcctaccgcc cattgatttc catacttatg
      301 cctgtctata acgttgaaat caaatggctc gaaaaatgca ttgattcggt acttgatcaa
      361 acgtatgatc actgggaact atgtatcagt gatgatgctt ctactgatcc agctatccga
      421 aagtgtctag aatcctatca agcaaaagat gatagaatta aagtcgtttt ccgacaagaa
      481 aatggacaca tcagtctggc aactaattct gcattggaaa tggcagaagg agagtttata
      541 gcgctcttag ataatgatga cgaattacct ccatttgcct tatatgaagt ggcaaaagtg
      601 ctaaacgtac atccagaact ggatttgatc tacagtgacg aagataaaat cgatgcagat
      661 gggaatcgct ttgacccgca cttcaaagca gactggtctc ccgatacatt gatgggaaat
      721 aattatatct ctcacttagg cgtatatcgg acaagcattg ttaaggaact tggcggtttc
      781 cgtaaaggat atgaaggctc tcaagattat gatttggttc ttcgtgtgac agaacaaatt
      841 cctgcagaac acatttacca cattgaccgt gtcttgtatc attggcggac gatcccggga
      901 tcaactgcaa gcaatggaga agctaaaagc tacatctatg attctggagt gaaagcattg
      961 acagatgctc tatctagaag aaatatcaag ggaagcgtac atcctggcag aatttctggt
     1021 ttttatgaaa tcacttatga tgttttgcaa gaagacttgg tcagtgtgat cattccaact
     1081 aagaatggct atgaagatct aaaaacttgt gtggattcga tcatcgaaaa aacgtcttat
     1141 ccaaattatg aaatcattat tgcagataat ggaagtacag atcctaaaat gcaagaatta
     1201 tttgcagaat acaagcatca gctgaaagac cgatttatcg tcgaattaat tgacattcca
     1261 ttcaattatt cacgtatcaa caatctggca gcagaaaaag caaacggcaa atacttttta
     1321 ttcttgaata acgatacaga agtgattgaa cctgactgga tgacagcgat ggtttcttat
     1381 gcacagtttg atcgaatcgg ctgtgtagga gcaaaattat tttatccgga tgatacaacg
     1441 cagcatgcag gtgtattatt agggatcggt ggcgttgcag gacatgcatt gaataactat
     1501 gatcgaacac attgtggtta ctttggccga ttggtcattg acgtcaatta cttagcagtc
     1561 actgcagctt gtatgatggt caaggcagct gacttcaatg ctgtcaatgg atttgatgaa
     1621 atattagaag tagcattcaa cgatgttgac ttgtgcttga aagtttatga actgggtcgt
     1681 tacaatgtct atgcacatca agcagaattg taccattt
//
LOCUS       DADGKS010000218         1703 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.226, whole genome shotgun sequence.
ACCESSION   DADGKS010000218 DADGKS010000000
VERSION     DADGKS010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1703
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.226"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(341..574)
                     /locus_tag="JXV47_003146"
     CDS             complement(341..574)
                     /locus_tag="JXV47_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HAX1489107.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(589..1539)
                     /locus_tag="JXV47_003147"
     CDS             complement(589..1539)
                     /locus_tag="JXV47_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAX1489108.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(1536..>1703)
                     /locus_tag="JXV47_003148"
     CDS             complement(1536..>1703)
                     /locus_tag="JXV47_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese ABC transporter substrate-binding
                     protein"
                     /protein_id="HAX1489109.1"
                     /translation="SATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPK
                     QKFLRKKERKL"
BASE COUNT          515 a          326 c          214 g          648 t
ORIGIN      
        1 cactttctat taatttttgg tgagttgtaa tataatctct ggtttctatg ggtacttcct
       61 cctaataaga tgaattaact atattatctt acacaggact tgaagtttca atcgttaacg
      121 tctattactg aactcattcc ttagagctaa actaatgaga aagagcaaaa taactgatac
      181 aaaaagcaat cctacaagaa ttaatagact catctaaatc attcaccttt tctaaaataa
      241 tccgagaaag atttaaaaaa attatatcca gctattaggg taagtcctat cataatcact
      301 ccaatagcca ttttcttatc ctccctaaaa ataaagtctt ttacttaaaa ccttttttgt
      361 aatcgtcaat aaattttttc cctttatcag ttaattgaaa tcctatatct aaatagtcct
      421 catatctaag tttagccagc atctcactta cagatgctgg actaacactt agaacttttg
      481 ctaaatcatt attttttaat ttcttttttc tttttgataa ttcctgaatt gctagtaaat
      541 aaattagtat agtagttgtt ttaatttgta ccatacctac cctccaaatt atttcgaaag
      601 gccttcagca attttatcca ggttccattt catcatcgca tagtaactat caccatcttg
      661 tcctttttct gcaattgaat cagtaaaaat cgttgaatag ataggaatat tggtatcttt
      721 tgatactgtt ttcattggtc tatcgtccac actgctttct acgaataagg agggaacttt
      781 tgttgtgcgt aatttttcaa ctaagtgttt tatttgatct ggtgttcctt cttcttcagt
      841 gttgatttcc caaatgtaag cagaaggcac attatacgct ttcgagaaat atttaaagca
      901 tccttcactt gtaacaatca tttttttatc attcggaatt gaagcaaatt tagatttagc
      961 ttctttgtct agagaatcca atttttcaat atacttatct agattttctt tatagaattt
     1021 tttattatca ggatcttttt ccgctaactg tttttcaata tttttagcgt aaataatacc
     1081 gttttctaaa tttaaccaag catggggatc ttccttccct ttctcactct gaccctctaa
     1141 gtaaataaca tctatgccat cacttgctgc aaaatagtct ttgttttcct ctttgttcgc
     1201 attttttact aattttgtaa accaagcatt tcctccagtt tccaagttaa caccgttata
     1261 aaaaatcaaa tctgcttttg aagttttttg aacatcttca ggcaaaggtt catattcgtg
     1321 gggatctttc ccaataggta cgatactgtg taaatcaatt ttatcttttg ctatattttc
     1381 agtaatatct gctaaaatcg aattagtaac tactaccttt aatttttcgt tcgaagccac
     1441 tgtatctttg tctttactat ttgttgaaca tgccccgaat ataaaaagag caatcaaaat
     1501 ccccagactt cccagtactg ctttccattt tctcatcata actttctctc cttctttctt
     1561 aaaaattttt gttttggtga gattagaaaa ctaattacaa ataagaatgc cgctgttaaa
     1621 acaatacttg atcctgctgc tatgttaaaa ctataaccaa tgaacaaacc tagcaatgat
     1681 gagcacgctc cgactgtcgc cga
//
LOCUS       DADGKS010000219         1680 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.227, whole genome shotgun sequence.
ACCESSION   DADGKS010000219 DADGKS010000000
VERSION     DADGKS010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1680
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.227"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            64..972
                     /locus_tag="JXV47_003149"
     CDS             64..972
                     /locus_tag="JXV47_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HAX1489110.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKINYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FERWRQEQEHSFQDWREGQESDYLAWFESIKDILKTIDPGGVMLAELTDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVAFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            972..1592
                     /locus_tag="JXV47_003150"
     CDS             972..1592
                     /locus_tag="JXV47_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489111.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
BASE COUNT          602 a          246 c          377 g          455 t
ORIGIN      
        1 cagtattata gtgcaagtgc aatttcttcc attgtcatac caccaaaata gggaggtgat
       61 ttaatggcaa agtggaatgt catattaagt acaacagaac cctataatta cgtggggatg
      121 attcaagttc gacaaggcaa taagaataca gaggttatgg aagcgactat agttgaaaat
      181 ggtcttccct acgatttatc agaatgtaag gtatattttg aatcagttgt aggtgggaaa
      241 tatccagtcc aattagaaac aaaaattgtg gatgctaaaa aagggaaaat taactatatt
      301 tttgataaat attccatgca gtgtttacat cgacaaacag ccaatttcat tatatttaaa
      361 ggagaagact tgattggaac aactcaagac ttctcttatt ttgtcattaa tgctgtttca
      421 aaaacagaag gagaaatggg ttcttattgg caatcaatcg aagatttaat tgcggatatg
      481 acggacttta ttaatgaaaa taaaggcgat tttacggact ggatgaatga aaggaaagaa
      541 gaatttgaac gttggagaca agaacaggaa cacagtttcc aagattggag agaaggacaa
      601 gaatcagact atttggcatg gtttgaatca atcaaggata ttttaaagac gattgatcca
      661 ggtggagtca tgttagccga actaacggat gcgcgagtag atattcaagg agttcgtcat
      721 gcgtctattt cagagcgttt gctggcagat atggactatt tatatcagaa attgcgagca
      781 acgcttttca cgattgaata cggggagatt gaagtgactg atattttgca ggatgatctc
      841 ttttcagata atcatgaagt cgaaaaagtt ggaactgtag cattcccgat tgaagaagga
      901 gccttgatca tcgcaaccgt tgatgatcca aagcaaaatg tgttcactct tgagaaagtt
      961 ggggtgatct aatggctaaa actaaacgaa tgatggaaac ggatgaaaaa acgggtgtac
     1021 aacgccaatt ctttccaatc acacatgctt ccgcagttct tgggttagaa gaaataatag
     1081 caggagaagc aacagtttta tctgttaatg gaaaaattgg agccgtcgtc attactaaag
     1141 aagatttggg attagagaat gttctcacag aattacccta tgcaagtgaa gaagatgacg
     1201 gcattatcac ggcagaaatg tatcaaaaaa ttttaaacag tggagaaggt gactacgtgt
     1261 tgccagttgc cactatcgac cgtttgggtg gcataaaagt tggtgaatta ttgacgattg
     1321 atgagacagg gaaagtctct gcagtcagac aatctgatgt caatttttcg ctggagttaa
     1381 aagaaaaact cgattcactg aaaaattata ctgctggaga aaacatcact attgatgaag
     1441 atggaacaat tagttctaca ggtggtagtg ggactggtgg tgtcaatcag tcatatgtag
     1501 atcaaaaatt ccaagaagct gtaaatcaag cagaaaatta cacaaacgaa agaattccaa
     1561 attttacttt tgaaaaaatt ggggaggtat agagaatgac agatatcgta aaaataaaac
     1621 aaagcaatgt acaggtttat ccacaaactc attggaatgc tatagaaggc aaaccaacaa
//
LOCUS       DADGKS010000220         1677 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.228, whole genome shotgun sequence.
ACCESSION   DADGKS010000220 DADGKS010000000
VERSION     DADGKS010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1677
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.228"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            64..972
                     /locus_tag="JXV47_003151"
     CDS             64..972
                     /locus_tag="JXV47_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HAX1489112.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDLQGVR
                     HESISERFLSDLNYLYQKMKAALFTIEYGEIEVTDILQDDLFSDNHEVEKIETVEFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            972..1589
                     /locus_tag="JXV47_003152"
     CDS             972..1589
                     /locus_tag="JXV47_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489113.1"
                     /translation="MVKVKRMMETDESGVKRQFMPITHVSAVLGLEKMISGQSKVLSV
                     NGKYGAVILTKADLGLENAITELPYASETSDGILTAEMFQKIVNGEGGTYILPIATPE
                     QLGGIKVGELLEVTEEGVLSATKQTDFNFSEELKGKLESLKILKAGANISIAEDGTIS
                     STGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
BASE COUNT          620 a          226 c          348 g          483 t
ORIGIN      
        1 cagtattata gtgcaagtgc aatttcttcc attgtcatac caccaaaata gggaggtgat
       61 ttaatggcaa agtggaatgt catattaagt acaacagaac cctataatta cgtggggatg
      121 attcaagttc gacaaggcaa taaaaacact gaagttatgg aagctacaat tgtcgaaaat
      181 ggtcttccat atgatttatc agaatgtaag gtatattttg aatcagttgt tggcggaaaa
      241 tatccagtcc aattagaaac aaaaattgtg gatgctaaaa aagggaaaat caaatatatt
      301 tttgataaat attccatgca gtgtttgcat cgacaaacag ccaatttcat tatatttaaa
      361 ggagaagact tgattggaac aactcaagac ttctcttatt ttgtcatcaa tgctgtttca
      421 aaaacagaag gagaaatggg ttcttattgg caatcaattg aagatttaat tgctgatatg
      481 acagatttta ttaatgaaaa taaaggcgat tttacggact ggatgaatga aaggaaagaa
      541 gaatttgatc gctggagaga ggaacaggag aatagtttcc aagattggag agaaggacaa
      601 gaatcagatt acttgtcatg gtttgaatca atcaaggata ttttgaagtc tatcgatcca
      661 ggtggagtaa tgttagccga attaatggat gcacgtgtag atcttcaagg tgtacgccat
      721 gaatcgattt ctgaacgttt cctatccgat ctaaattatt tgtatcaaaa aatgaaagca
      781 gcacttttca cgattgaata cggtgaaatt gaagtgactg atattcttca agacgatctc
      841 ttttcagata atcacgaagt cgaaaaaatt gaaacagtag aatttccaat tgaagaagga
      901 gctttgatta ttgcaactgt tgatgatcca aaacagaatg ttttcactct tgagaaagtt
      961 ggggtgattt gatggttaaa gtaaagagaa tgatggaaac tgatgaatct ggtgttaaac
     1021 gtcaatttat gccaattaca catgtctctg cagttttagg cttagaaaaa atgatatcag
     1081 gacaatcaaa agttctttcg gttaatggta aatatggtgc agtcatttta acgaaagctg
     1141 atttaggatt agagaatgca attactgaac taccttatgc aagcgagaca agcgatggta
     1201 ttcttactgc tgaaatgttt caaaagatcg taaatggaga aggtggaaca tatattttgc
     1261 cgattgctac tcctgaacaa ttaggaggta taaaagttgg ggaactctta gaagttactg
     1321 aagaaggtgt tttatctgca actaagcaaa cagacttcaa tttctctgaa gaattaaaag
     1381 gaaaattaga atctctaaaa atattaaaag caggtgcaaa tatatcaatt gcagaagatg
     1441 gaacaattag ttctacaggt ggtagtggga ctggtggtgt taatcagtca tatgtagatc
     1501 aaaaattcca agaagctgta aatcaagcag aaaattacac aaacgaaaga attccaaatt
     1561 ttacttttga aaaaattggg gaggtataga gaatgacaga tatcgtaaaa ataaaacaaa
     1621 gcaatgtaca ggtttatcca caaactcatt ggaatgctat agaaggcaaa ccaacaa
//
LOCUS       DADGKS010000221         1639 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.229, whole genome shotgun sequence.
ACCESSION   DADGKS010000221 DADGKS010000000
VERSION     DADGKS010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1639
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.229"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            415..>1639
                     /gene="ltrA"
                     /locus_tag="JXV47_003153"
     CDS             415..>1639
                     /gene="ltrA"
                     /locus_tag="JXV47_003153"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAX1489114.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRL"
BASE COUNT          585 a          299 c          388 g          367 t
ORIGIN      
        1 acttggtggt gaaagtccac tacaggcttg gcagtaggaa ctgttagcga aagacaaggc
       61 ggcaatcgtg aggttgtggc tgaaggaagt cggacgcaaa ctcctgaact gacgaacaga
      121 aactagatac aaggctgaat taggtcggat aagtcttcat cacaagacaa agtccaatac
      181 tgcccgaaac ctatacagta aatctagcag ttacatggga ggaaagtttt cactcttacc
      241 gggggagatc tcatgagggt gttgtgggcg ttgaatgaaa acaaaccagc acaacgatca
      301 tggcgacatg atggtgaatc atgagaagtc agccgaggtc atagtagtaa cgacactgac
      361 cgttacgaag gactgaacaa taagaatctt gaataattta ggaggtgtga gaagatgcga
      421 cgaccgcaga aaacaagaaa acttggctat catcaaagag ctagtgtgga acacgaaggg
      481 tatgatgaag tgcgcagcac ttcttgcggt gaacagagga aacaagatgg tgtagaaaat
      541 ctgtttggga gaattctaga tcggaataat ctcaatcaag cgtatcttca agtagtcaga
      601 aataaagggg cggctggtgc agatgggatg accgtcgatc aactgcttcc ttacttgaaa
      661 gagcaccgcg aggaattact atccaattta cgccaaggga actataaacc tcagcctgtt
      721 ttgcgagtag aaataccgaa accaaacggc ggtgtaagaa aactaggaat tcccacggtt
      781 attgatcgta tgcttcaaca ggcaatcaat caagtgttac aaccgctatt tgaaccagaa
      841 ttctcagata atagttatgg gtttcgccca aatcgcagcg cacatgacgc agtgaagaaa
      901 gcaaaatctt attatgaaca aggttaccga tatgtggtgg acattgatat gaaagcctac
      961 tttgacaccg taaatcacga taagctgatg tatttcattg agcggaaagt aaaggacaaa
     1021 caagtcctaa aactgatccg tcaatactta atgagtggtg taatggaaaa tggactcatc
     1081 acaacaactg aagaaggaac gccccaagga ggcaatctct ctcccctgtt aagtaacatc
     1141 tacctgaacg aatttgatca agtgctagaa aatctaggac ataaatttgt tcgatacgcc
     1201 gatgactgca atatctatgt tagaagcaaa cgagcaggac agcgtgtgat gaagaaatcc
     1261 attcaatttc tcgaagaaca actaaagttg acggtaaatc gagaaaagag tgcggtagga
     1321 agtccattga aacgaaagtt tcttggattc tgcattctgc caacaaagaa aggtattaaa
     1381 attcgccctc acgcaaaagc aaaacagcgt gtgaaaagca agctcaaaca actcactaaa
     1441 agaaaccgtg gaagaagtat ccaacttatt ttaaaagaaa tcaagcaact aatgactggt
     1501 tggatcaact actatggaat tggtgagatg aaagaattca tgagggagtt aaacggttgg
     1561 ttgaagcgaa gaatcagaca atatatttgg aaacaatgga agaatccaag aaccaaaaga
     1621 aaaaatctga ttcgtttag
//
LOCUS       DADGKS010000222         1604 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.232, whole genome shotgun sequence.
ACCESSION   DADGKS010000222 DADGKS010000000
VERSION     DADGKS010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1604
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.232"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            635..>1604
                     /locus_tag="JXV47_003154"
     CDS             635..>1604
                     /locus_tag="JXV47_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HAX1489115.1"
                     /translation="MANENQLSEIQSKIEGRGAEKRTTINQLEKLNRISNRRLSVDDK
                     VHPLKLSWSIDRITIVGKLNDTIAYWTQNGVVFVDFEQLMRLNENQGYLKSVGTNGWQ
                     LFDQYGEDIAYIEMLKFHPDKGRIDFNPNKIGEFLKGSMKQFIHDLFLDAHFSRADIA
                     CDILGVPDDFITQYRIVDPVSFKPIYGRSGKLETAYWGSRASERQVRMYNKKLEQERK
                     KQIVPKEIETWWRIEMQLRRGKATDWHAMVRESLDSFASPHYLPGDVKPVDRIMIKGL
                     NQDHSEWAYISRNLKYRLRKLLKEESQNDELTNHLRETFKESANDLK"
BASE COUNT          540 a          251 c          364 g          449 t
ORIGIN      
        1 aatacaagca tttctcataa taatcgtgag ttaactgata gccaaaaaat caatggtttg
       61 tctggtagaa aataattagc agatttacaa gtgggaaata aaaagctgaa agaagaaaat
      121 tgcatttcaa actacatttt ctacaatagc tctaaaatgg catattttgc gttctgagcg
      181 gttttagcgt ttatttcgtt tagttatcgg cacaatcgtt aaaacacgtt agaggagcga
      241 aaatggagcc tgtaaggcga ctggtagcgg aacgatcgtg ttagattgtg aaaaccgata
      301 gctgaatgaa ataaacagcg ggtgcgccct ttccatttcg gcaggaggag gctcaagggg
      361 ttcggggaat gaaattccct gaggtctttt tattttttta ggaggagtgc tataatcaaa
      421 gaaaacgaga aaaaagagca aaataaaagc cgagcagtgc gctaacactc tcgactattt
      481 acggaaacta cttcacctag ctccgtaact caggttcatt atacgaatat ttttaggttt
      541 cttcaagcta gagatttttg gatatgaatt tttagggtta cgtgaactct ggaaattctt
      601 tccaaaagtc tcttttttcg tctggaggac gaaaatggca aatgaaaatc agttgagtga
      661 aattcaatca aaaattgaag gtcgaggggc agaaaaaaga acaacgataa atcagctcga
      721 aaaacttaac cgtatttcta acaggcggtt aagtgttgac gataaggtac accccctaaa
      781 attaagttgg tcaatcgatc gaattacaat cgtcggaaaa ctgaatgata ccatagctta
      841 ttggacgcaa aatggagttg tgtttgtcga ttttgagcaa ttaatgcgtt tgaatgaaaa
      901 tcaagggtat ttgaagtcgg ttggtacaaa tggttggcaa ttatttgacc aatatggaga
      961 agatatcgcc tatatcgaaa tgttaaaatt tcaccctgac aaaggtcgta ttgattttaa
     1021 tccaaataaa attggcgagt ttttaaaggg gtcgatgaaa caattcattc atgatttgtt
     1081 tctggatgcg catttctcac gtgcagatat tgcttgcgat attctcggtg ttcctgatga
     1141 ttttattacc cagtatcgaa tcgttgaccc tgtgtctttt aagccaattt atggccgttc
     1201 tggcaaatta gaaacagcgt actggggtag tcgtgccagc gagcgacaag tgcggatgta
     1261 caacaaaaag cttgaacagg aacgaaaaaa acagattgta ccaaaagaaa tcgaaacatg
     1321 gtggcgtata gaaatgcagc taagacgtgg caaagcaaca gattggcatg cgatggttcg
     1381 ggaaagttta gatagctttg caagtcctca ttacttgcct ggagatgtaa aacctgttga
     1441 tagaattatg ataaaagggc tgaatcaaga tcattcagag tgggcgtata ttagcagaaa
     1501 tttgaaatat agattgcgca aattgttgaa agaagaaagc caaaacgatg agttgacgaa
     1561 tcatttacga gagacgttta aggaatctgc aaacgacttg aaaa
//
LOCUS       DADGKS010000223         1602 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.233, whole genome shotgun sequence.
ACCESSION   DADGKS010000223 DADGKS010000000
VERSION     DADGKS010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1602
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.233"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(1..1283)
                     /locus_tag="JXV47_003155"
                     /pseudo
     CDS             complement(1..1283)
                     /locus_tag="JXV47_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          440 a          299 c          334 g          529 t
ORIGIN      
        1 ttcttagttt tcttaaaata ttttcctcga tataaaaaga ttcgttctcg gtagttttga
       61 aagtttctat agccataggc aattcgtttt agtactttga tatggttatt caaacattct
      121 atagggccgt tggaataggg aacgcgcaac gctcgtttga tttctgtttg gtatttcttg
      181 aaggtcgtga acactggttg gtagtgctct ggcaactcct tgtagtcttc ttttaggagc
      241 gcgacgaatt caggaacatc ttgtcttctg ataacggaaa gaaaatcctg gtagacttcg
      301 tagcctcgct ttaaggaatc atcataagat aatagccgat cgactatctc tgcttctgtc
      361 agatgatctc gaaatgacgg acgccagtag cgatgctgac ctttcaattc ccacgcattc
      421 ttttgaagta gtttccagta tttctttaag tgcttcgacc gacgatcccc ttttttaaag
      481 gtcttcatta cttgaattcg gtggttggta aaagcccgac caatgtgttg gctaatatga
      541 aagcgatcgg cgacgattcg ggcattcgga aaacactctt tcaccaatgt gcgatagggt
      601 gtatagaaat ctgaaaccac tagacgcact tgttcacgga cttttatagg gtagcgcaag
      661 aaatagtcgc gtaaaggatt gagttgccga ttttccacaa tatcaatcag ttgatgggtc
      721 ttgccgtcca tcatgacaaa gctcatggct cccgagacat ttttcactga tttgaattca
      781 tcgaaacaca ccacttctgg taacagctgg ctcaaagaaa tggttttagg ccgaaggctg
      841 cgaagtattc gaatgacagt ggtcggagaa atgtgcttca tacgtgcgat caaagacata
      901 gaaagaggtt cgcttaatag ctcaagaatg gcttgtttga ctctgcgagc aatggagcag
      961 cgacgatcac taactgaatc ttctgctaaa aaagtctttc cacagtgttt acatttgaag
     1021 cgctgtttgt taatccgcag aatggtcttg tagttactga catcattcaa taagatggat
     1081 acttttttcc agccctattt aatgatcgtt tgttcatttt gatagtggcg atgaaagcat
     1141 tcctccggtt gataggtcaa tgtgccatca aaagcaaaac atgtttcgtc attgatgcgc
     1201 tctttgcgaa aggcatcctc atgaaaggta agatttaggt ctagaatatc tagtaactct
     1261 ttggtaaact ctgaatagga catcttgaaa cactactttg aatggttttt gtcgacttta
     1321 ttctaaagga ttttaaggtg tctgtttgcg tttattagaa aaaagaaaaa gtattggcaa
     1381 cagaaggcgt caccaacact agatattata gatcccttat tttcttcgct tcaaattgtc
     1441 aaggagtcat cataaatttt gtatggattc ttttgtttgg gtagtagtct tctaaataat
     1501 cttggattaa caccttcatc tctattttac ttttatattt gttggagtcg attaattctc
     1561 atttgattga tcgatgaaac gcttcaatta ctgcattgtc aa
//
LOCUS       DADGKS010000224         1600 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.234, whole genome shotgun sequence.
ACCESSION   DADGKS010000224 DADGKS010000000
VERSION     DADGKS010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.234"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            76..1395
                     /locus_tag="JXV47_003156"
     CDS             76..1395
                     /locus_tag="JXV47_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011674482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /protein_id="HAX1489116.1"
                     /translation="MKANILEAIFFDEHHNWDNFVEKYGRKIRLVVKREVNKFRYCGD
                     IQKGYRLFVCEGCHQTKFVPLKCRGKFCPTCATGESQRWSAVVANDMFKVTHRHVIFT
                     IDEGLREIFMMENYRDSLLKGLMDEAAKIILAYFEKRKVKAGIVATIHTFGSKLEFNP
                     HVHMVVTMGGLTRDGSWEEYDYLPFSMLRKYWKNAVLKLIRRTLGEWDKQRVQSRLQA
                     AYKNNGEGFYVNAPKRSRTNLKSLLQYISRYMKRGPIALSRILMYDGDTVMFNYMDKR
                     TNTKETMTMSIDEFIAALIRHIQNKNFKTIRRYGIYSRRIKTLMKKVMKEYQKRVKKL
                     FINLNEALRPKSWEERITEEFGENPLECSCCGEYYEFVGMSVRKNGRLVIKYAKDNHA
                     KRFMREENRKIDQKEFRQQYEEEKEKTFKAIRWDWERQREIYMSKLW"
     gene            1367..1564
                     /locus_tag="JXV47_003157"
     CDS             1367..1564
                     /locus_tag="JXV47_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489117.1"
                     /translation="MKFICLSCGEKESIPMDVVKFLDDADIANDPNNPPQFTCEKCGK
                     EMYPEYYRNALGIEFKISDVQ"
BASE COUNT          573 a          245 c          360 g          422 t
ORIGIN      
        1 gttaagggct aaaaaggctg cactaccagt cttttagccc ttttcatttt gtttttgaac
       61 aagtaaaata ttactatgaa agcgaatatt ctcgaagcaa tcttttttga cgaacaccat
      121 aattgggata actttgttga gaaatacggg cgaaagattc ggctagtcgt caaacgggaa
      181 gtaaacaagt ttagatattg tggagatatt caaaaaggat accgactgtt tgtctgcgag
      241 ggatgtcatc aaacaaagtt tgttcccttg aaatgtcgtg gaaagttctg tccaacgtgt
      301 gcaacaggtg aaagccaaag gtggtcagcg gttgtggcga atgatatgtt taaagtgaca
      361 catcggcacg taatctttac gatcgatgag gggttacggg aaatctttat gatggaaaac
      421 tatcgagatt ccttactgaa aggactaatg gatgaagccg caaaaattat tcttgcctat
      481 tttgagaaaa gaaaggtgaa ggcaggtata gtagctacaa tccacacctt tggatcaaaa
      541 ctagaattta atccgcatgt tcatatggtt gttactatgg gtggcttaac aagagatgga
      601 agttgggaag aatacgatta tttacctttt tctatgttaa gaaaatactg gaaaaatgct
      661 gtattgaaac taattagacg aacgttaggt gagtgggaca agcaaagagt tcaatcaaga
      721 ttacaagctg cgtacaagaa caatggagaa gggttttacg taaatgctcc taaaaggagc
      781 aggacaaatc taaagtcact actccaatac atcagtcgtt atatgaagcg tggcccgatc
      841 gcattaagcc gaatcttaat gtatgatggc gacactgtca tgttcaacta catggacaaa
      901 cgaacgaata ctaaagagac gatgaccatg agtatagacg aattcatagc tgcactgatt
      961 cgccatattc aaaataagaa tttcaaaacg attcgtcgct atggaatcta tagtcgtaga
     1021 atcaaaacat taatgaaaaa ggtcatgaag gagtatcaga aacgagtaaa aaagctgttt
     1081 atcaatctga atgaggcctt aagaccaaaa tcctgggaag aaagaataac cgaagaattt
     1141 ggtgaaaatc ccttagaatg ttcttgttgc ggtgagtact atgaattcgt tgggatgagt
     1201 gtgcgcaaaa atggacggtt agttattaaa tatgcgaaag ataaccatgc aaagcggttt
     1261 atgcgagagg agaatcgaaa aattgaccaa aaagaattca ggcaacagta tgaagaagaa
     1321 aaagaaaaaa cttttaaagc aattcgctgg gattgggaac gccaacgtga aatttatatg
     1381 tctaagttgt ggtgaaaaag aatcaatccc aatggatgta gtaaaatttt tagatgatgc
     1441 agatattgca aatgatccga acaatcctcc ccaatttacc tgtgaaaaat gtgggaagga
     1501 gatgtatcca gaatattata gaaacgccct tggaatagag tttaagatca gtgatgttca
     1561 ataagaaggt taatcataca aaaagtccac cggagaattc
//
LOCUS       DADGKS010000225         1592 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.235, whole genome shotgun sequence.
ACCESSION   DADGKS010000225 DADGKS010000000
VERSION     DADGKS010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1592
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.235"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..125
                     /locus_tag="JXV47_003158"
     CDS             <1..125
                     /locus_tag="JXV47_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAX1489118.1"
                     /translation="TPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            147..1544
                     /locus_tag="JXV47_003159"
     CDS             147..1544
                     /locus_tag="JXV47_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAX1489119.1"
                     /translation="MKRYQFPKNFWWGSAASGPQTEGRISGDGKGENIFDYWYKNEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HHYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFQLFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKAYHEMDQSGVI
                     GIILNLTPSYPRDESNPEDVKAARIADAFFNRSFLDPAVKGEFPSELIERIKELDLMP
                     EIHPDDLTIIKENTVDLLGINYYQPRRIKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEKGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDRNGFEA"
BASE COUNT          570 a          263 c          345 g          414 t
ORIGIN      
        1 tcacgccacc aacagataaa atcggggaac gagcagcaga acagctgttg aaacgaatca
       61 aaaaagaaga ggaagaaaat gaaaaagtga ttgtgatgga aaatatcata catggaatca
      121 actaaaaaag aaaaagaggt gctttgatga aaagatatca atttccaaaa aatttttggt
      181 ggggctctgc agcaagtggt ccacaaacag aaggaagaat ttcaggcgat ggaaaaggag
      241 agaatatttt tgattattgg tacaaaaacg aaccgcaaaa gttctttgat caagtaggac
      301 ctgaaaaaac ctcgcaagtt tatacgaagt atcaagagga tgtacagttg atgaaacaga
      361 ctgggcataa ttcatttcga acctctatcc aatggagccg tttgatacct gatgaatctg
      421 gaacaatcaa cgaagaagcc gttcgtttct atcatcacta ttttgatgag ttgattgaaa
      481 acggtatcga accctttgtt aatctgtatc atttcgatat gccgatgtat ctgcaagaaa
      541 aaggcggatg gttgaaccga gaaacggttg aagcctatga aaaatacgca aaaagttgtt
      601 ttcaattgtt tggctcgaaa gtaaaaaaat ggtttaccca taatgaacca atcgttccag
      661 tcgaggcagg ctatttgtat cgatggcatt atccggaaga atcagatatg aaaaaggcaa
      721 tccaagttgg ttatcatgaa gcgttggctt cagcattagc catcaaagct taccatgaaa
      781 tggatcaaag cggtgtgatc ggaatcatct taaatttgac accgagttat ccaagagacg
      841 aatcaaatcc cgaagatgtt aaagcagcac gaatagcaga tgcgttcttc aatcgttcat
      901 tccttgatcc agctgtaaaa ggcgagtttc ccagtgaatt gattgagaga ataaaagaac
      961 tcgatctaat gccggagatt catccagatg atttgacgat cattaaagaa aacacagtag
     1021 atcttttggg aattaattat taccaaccac gccgaataaa agcaaaagaa acaccaatcg
     1081 atactaaaaa cggtcctatg cctgaggatt acttcgacaa ttatgaaatg cctggtcgta
     1141 aaatgaatcc ttatcgcgga tgggagatct atgaaaaagg aatctatgat attttgatca
     1201 atgtacgaga tcattatggg aatatcgact gttttatttc tgaaaacggc atgggtgtag
     1261 aaaatgaagc acgatttatc aaggaagatg gtatgatcca cgatgattat cggatcgaat
     1321 ttgttcaatc tcatctgaaa tatgtccatc aagccattca agaaggtgcc aattgtttag
     1381 gttatcatat gtggacatgc atggataact ggtcgtggac caatgcctat aagaatcgtt
     1441 acggttttat ttcagtagat ttagcacaag atggaaaaag aacgatcaag aaatcgggtc
     1501 attggttcaa agatgtatca gacagaaatg gatttgaagc ttaaagaata gccaagagag
     1561 aatgtatgaa aattcccgtt cttaccgctt ca
//
LOCUS       DADGKS010000226         1558 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.236, whole genome shotgun sequence.
ACCESSION   DADGKS010000226 DADGKS010000000
VERSION     DADGKS010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1558
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.236"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..841)
                     /locus_tag="JXV47_003160"
     CDS             complement(<1..841)
                     /locus_tag="JXV47_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HAX1489120.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRI"
BASE COUNT          500 a          312 c          266 g          480 t
ORIGIN      
        1 ctattcttga gctggctgca gctagtgagt gtctttcatt tatccataag ataaagcttg
       61 gattcaataa ataaataaat gttttggtta aagctgtgac cagcaaatga ggaaccgtgc
      121 gagccagttg atctgccaat gcaaacattt ctttaggtga aggcgctggc gtgtctgcca
      181 acggatactc cagtcccaat gcttggtaac cgtgcatacc atagcagtgg tacggtagta
      241 attctaacgg tacgaaccga tcaagatctg ccacaaaaca agcaatcgtc agcagctcgg
      301 tcaggttcat attgatacct ggaaccacag gaactcgaat tcgcacttcg cagttaggat
      361 actcaattaa aaagcgacga atattcttca aaatttgttg gttatctaag ccggtccatt
      421 gtttgtggag cttgctggta aacattttta catccacaaa caatgtatcc acatagggag
      481 ctaccttttg gatttcatta taagcaccac aaaagctggt ttccagtacg gtattgattc
      541 caatgtattt cgatttttgc aaaatttctt tagcaaaatc cgcctgaacc agtgcctcgc
      601 ctccgctaat ggtcactccg ccatccgagt gaaagtaaaa aacagcatcc ttctcaatct
      661 catccattac ctcttcagcg gtcatggtct ggccaaatcc tttttcaatc tgcttgcttt
      721 gtgattcggg aatcgaacac caggcacagc gtaatgggca gccctttaaa taaacaacgg
      781 tccgtaaacc agcaccatca tgtagagaac cctgttctat tcttaatact gttccttcca
      841 tatagatttt tgaattacac actagtttaa actaaaacac acaaggaaaa acttaccatt
      901 taatcataaa attagctcat ataaatatac taggatgtaa aatagactgg tcaaaatctg
      961 gtcaaaaaag aggactaata caggtagtcc tcttttttgt tattttaata ttctaaatca
     1021 ttttttattg gtttattccc ttattcgatg tagactcaaa tcactatatc actagatatc
     1081 aaacggcgtc atacggaatc aaaaacatca aatttgacct gttaaatggt cattgaataa
     1141 cattcaaaat caataaaacg gagtcagaca cggagtcaaa aacgctgaga gtaaaaaata
     1201 tatacagcct tgtaggtaaa gtaccacagg gctgtatatt ttttatttca gattacctta
     1261 aatgattcca tttacttttt atctcatttt ttcctactag ttagtatcaa atactctcct
     1321 attttctcaa taaactattt ttggatacat ggtatctgaa acagctaaaa ccttgtcatt
     1381 acagcaaaaa atcacgttat ccagactgta gacaaagtcc attttatgga tgatgtctac
     1441 agtcttttct tttataatag atttatgaaa acgaatgcaa ggagtgatag ctatgatgtc
     1501 taaaaacaat acgaatggta gaaatcaatt tgcgatgctt acgattgatg atctagtt
//
LOCUS       DADGKS010000227         1557 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.237, whole genome shotgun sequence.
ACCESSION   DADGKS010000227 DADGKS010000000
VERSION     DADGKS010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1557
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.237"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            639..>1557
                     /locus_tag="JXV47_003161"
     CDS             639..>1557
                     /locus_tag="JXV47_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HAX1489121.1"
                     /translation="MSKNGIIVNEWENLTALSNRRLNVQNLNTPLKLQWSIDRITIVG
                     KLKENIYYHTQNDVLILDFEQLMRVNEGNGYLKAVGNNGWQLLDQYEENIAYIEILKW
                     QDGKGRIDFNPNKIGHFLASSMKNFIHDLFLEPHFSRADIACDIIDVPDEFITQYRVV
                     DPVSFKPIYGRSGKLETAYWGSRASERQIRLYNKKLEQETKRKVVPKEVETWWRLEMQ
                     LRRGKATDWHNMVQESLNSFASLHFLPIDTTPTDRIMLAGLMSDQNFWSLLSRNSKYK
                     YRELLKEESQNDELTNHLRETFAESADNLK"
BASE COUNT          521 a          234 c          340 g          462 t
ORIGIN      
        1 aatacaagca tttctcataa taatcgtgag ttaactgata gccaaaaaat taatagtttg
       61 tctggtagaa aataattagc agatttacaa gtgggaaata aaaagctgaa agaagaaaat
      121 tgcatttcaa actacatttt ctacaataac tctaaaatgg catattttgc gttctgagcg
      181 gttttagcgt ttatttcgtt tagttatcgg cacaatcggt gaaacacgtt agaggagcga
      241 aaatggagcc tgtaaggcga ctggtagcgg aacggtcgtg ttagattgtg tagccgatag
      301 ctgaacgaaa taaatgctgg cagcgccatt ctatttcggc aggaggaggc tcaaggggtt
      361 cggggaatga aattccctga ggtcttttta ttttttctag aggagtgcta taatcaaaga
      421 aaatgagaaa aaagagtaaa aaaatagtcg agcagtgttg acgcactctc gacctttacg
      481 gaaactaatc acactagctc cgtaacttct taatcattat acgaatattt ttagatttct
      541 tcaagactag agattttttg gtaatgaatt tttaagagtt acgtgaactt ttgaaaattc
      601 tttccagaag tctctttttc tttgaggagg aacaaaattt gagtaaaaat ggcataatcg
      661 taaatgagtg ggaaaattta acagccctat ctaacaggcg gttaaatgtt caaaatttga
      721 acacccccct aaaattacag tggtcaattg accgaattac tatcgttgga aaactgaagg
      781 aaaatattta ttatcacact caaaatgatg tgttgatttt agattttgag caattaatgc
      841 gggtgaatga aggcaatggc tatttaaaag cggttgggaa taacggctgg caattattag
      901 accaatacga agaaaatatt gcttatattg agattttgaa atggcaagat ggcaaagggc
      961 ggattgattt taacccgaat aagattggtc attttttagc tagttcaatg aaaaatttca
     1021 ttcatgattt atttctagaa ccacatttct cacgtgcgga tattgcttgc gatattatcg
     1081 atgtgcctga tgagtttatt acacaatatc gagtggttga tcctgtttct ttcaagccaa
     1141 tttatgggcg gtctgggaag ctggaaacag cttattgggg cagtcgtgcc agcgaacgac
     1201 aaattcggct atacaataaa aaattggaac aagaaaccaa acgaaaagtt gtaccaaagg
     1261 aagttgagac ttggtggcgg ttagaaatgc aactacggcg tggcaaggca accgattggc
     1321 ataatatggt tcaagaaagt ttgaatagtt ttgcgagcct gcattttttg ccgattgata
     1381 caacacctac agatagaata atgctcgctg gtttaatgtc tgatcaaaat ttctggtctc
     1441 ttttgtcgag gaattcaaaa tataaatatc gggaattgct gaaagaagaa agtcaaaatg
     1501 atgaattgac gaatcatttg cgagaaacgt ttgcagaatc ggcagacaat ttgaaac
//
LOCUS       DADGKS010000228         1531 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.238, whole genome shotgun sequence.
ACCESSION   DADGKS010000228 DADGKS010000000
VERSION     DADGKS010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1531
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.238"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..852
                     /locus_tag="JXV47_003162"
     CDS             <1..852
                     /locus_tag="JXV47_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAX1489122.1"
                     /translation="GGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDD
                     IVDEADLRRGQPNIRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKV
                     LNGELGQMDDRYNYELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIG
                     LSIGMAFQIIDDILDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKK
                     AAMTEEDVDAVRKIVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQ
                     LILDRKD"
     gene            complement(1007..>1531)
                     /gene="scm"
                     /locus_tag="JXV47_003163"
     CDS             complement(1007..>1531)
                     /gene="scm"
                     /locus_tag="JXV47_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAX1489123.1"
                     /translation="TSASSDSTDTTSTTSDSTDTSASSDSTDTSTTTSDSTDTSASSD
                     STDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSD
                     TRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVI
                     GLRITFMSYKKSKR"
BASE COUNT          432 a          275 c          340 g          484 t
ORIGIN      
        1 ggcggaaagc tgttgcgtcc tgcctatcag ctattgttct cacaatttgg accagagcaa
       61 gatcgagaca aagccatcgc tttggcagct tctatcgaaa tgctccatac ggccacactg
      121 atccatgatg atatcgttga tgaagcggat ctgcgacgtg gtcagcctaa tatccgtagt
      181 cagtttggta atgtcgtttc tgtctatgca ggagactatt tatttgtctg ctgttttaaa
      241 ctattgtctg attactccac ttccttgaaa agtctccaat tgaattctcg cagtatggaa
      301 aaagtattga atggcgaatt agggcagatg gatgatcgct ataattatga actttctgta
      361 aaagaatatt tggaaaatat ttcaggtaag acagctgaac tgttccaatt aagttgttct
      421 gttggcgctt ttgaaagtgg aacaagcgag cgcttcgcaa aaaaagcagg agatatcgga
      481 ctttctatcg ggatggcctt tcagattatc gatgatattt tagattatac aaaagagagc
      541 caggaaatcg gcaaacctgt actagaagac atgcgtcaag gggtctattc tttaccgttg
      601 atctactctt tgcaaaaaaa caaaccaaag ctactacctt atttagagaa gaaagcggca
      661 atgacagaag aagatgtcga cgccgtacgc aaaatcgttg aacatacagg aggcgtggaa
      721 gaagctagga agttagcggc ctcttacaca gaaaaggctt tgaaggaaat aaagaaatta
      781 cctgccacct ctcttcgaac aaaagagaat ctcttttccc ttacccaact gattttggat
      841 cgcaaagact gaatagggaa aggttcgata cgtaaataaa tttctcagaa ggaaatctac
      901 gtgttttttg acaaattgaa ttgtagttct tgtatttatg ataaaaagca aaaataaaga
      961 gcaacgtccg ttagcgacgt tgctcttttt tatcttgaat atttttttac cttttcgatt
     1021 tcttataact cataaaagtg attcttaaac cgattacaag taatataacg cctgcgagtg
     1081 ttatccaatt attcgattga cttccagttt taggaagtgc tctttttgat ttgtttccat
     1141 tgtcattgct tgttttatta gttaagttaa agttcgtcct gttatccgaa cttgtttttg
     1201 agaaggagac acttgcatga cgtgtatcgc ttgtggtaga cgacgtgtct gtactatcgc
     1261 ttgaagttga tgaatctgag ctatcacttg tggtagagga tgtatctgta ctgtcacttg
     1321 aagctgacgt gtccgtgcta tcacttgtag tggtagatga atctgagcta tcacttgtgg
     1381 tagaggtagt atctgtactg tcacttgaag ctgacgtgtc cgtgctatca cttgttgtgg
     1441 tagatgtatc cgtactgtcg cttgaagctg acgtgtccgt gctatcactt gtggtagagg
     1501 tagtatctgt actgtcactt gaagctgatg t
//
LOCUS       DADGKS010000229         1529 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.239, whole genome shotgun sequence.
ACCESSION   DADGKS010000229 DADGKS010000000
VERSION     DADGKS010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1529
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.239"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..95)
                     /locus_tag="JXV47_003164"
     CDS             complement(<1..95)
                     /locus_tag="JXV47_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015528642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAX1489124.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVA"
     gene            complement(107..595)
                     /locus_tag="JXV47_003165"
     CDS             complement(107..595)
                     /locus_tag="JXV47_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAX1489125.1"
                     /translation="MFLKVGTGIAYMKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDYEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQEIKMTILDEVHVVNEEED
                     FF"
     gene            complement(672..>1529)
                     /locus_tag="JXV47_003166"
     CDS             complement(672..>1529)
                     /locus_tag="JXV47_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAX1489126.1"
                     /translation="YTQIKNDLKGELLLLNNLTTSIALDIGLKMTMNAPFKQIAVDAA
                     DKYSINVQYFEGFSQSSNIIISCMSGLGISDKLKDVFRHHLSDESIEVFTKEYRELRE
                     LIDQNDETYFDKTKLVITTSDLPRSFSIPNINVYDILDGDGAANLKHILSSEMKPVEF
                     NRLIQELIKFFSLEGIADRLNFLNPTIVMSEVETVISKYENYYHFTLNGRVKLNLYMH
                     TALMMERLFLARTEKAEEPNYDMKPDEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLY
                     ELLGPYIQK"
BASE COUNT          470 a          320 c          222 g          517 t
ORIGIN      
        1 gctactacta acccggttaa atttagactc tttgtccaag tcatcgctac ttgtccatga
       61 attaatcgtt catcaattcg cactgcttta atcatttttc ttcctcctaa aaaaaatctt
      121 cctcttcatt tactacatgt acctcatcaa gaatggtcat ctttatttcc tgttggcatt
      181 tatttaccag ttcctgaata tcctcctttg ttaattcctt ggttgccaat actatttcga
      241 gcagaattgg cagattaaag ccagacaaaa tagttacagc aatctctttc tccaaaaagg
      301 ttttggtaat cttctgattg acacttccgc caaataaatc ggtaaaaaca aaaatctgat
      361 cctgctcgtt cacctggttt acaaatacat tcaactcctg ttcataatca cactcatcca
      421 cataagcatt aatcaccgta atctcttgaa ccttccccgt cagtaattga atactgctaa
      481 gaaagcctga agctaagtga ccgtgagtcg ctattagaat tttcttcata tggttaattc
      541 ctttctttct gttcactttc atataagcaa ttcctgtgcc aacttttaaa aacattggtt
      601 taatcacgtt aattcacata aaaaaaagtg tctaacctga aaaaatcaga ttagacactt
      661 ttttagacac tttatttttg aatatacggt cctaataatt catagagcag cgaaagctca
      721 taagcattga ctttaaaatt atatttcatc tccattgatt gaaaaatact tctcgaaaca
      781 taataaaatt catcttcatc tggtttcata tcataatttg gttcttctgc tttttctgtc
      841 cgcgccaaga ataaacgttc catcatcaat gccgtatgca tataaagatt tagttttacg
      901 cggccattta aagtgaaatg atagtaattt tcatatttag aaatgactgt ttccacctca
      961 ctcatcacga ttgttgggtt cagaaagttc aaacggtctg cgattccttc caatgaaaag
     1021 aattttatca gctcctgaat caaacggtta aattctaccg gcttcatctc agaactcaaa
     1081 atatgcttca aattggctgc tccatcacca tctaaaatat catatacatt gatattagga
     1141 attgaaaagg aacgtggaag atccgaagtc gtgatgacca attttgtctt gtcaaaataa
     1201 gtttcatcat tttggtcgat taattcacgt agttctctgt attccttcgt gaaaacttcg
     1261 atggactcat ccgataaatg atgacgaaaa acatccttca gtttatccga gatacccaat
     1321 cccgacatgc aggaaatgat gatgttgcta ctttgagaaa agccttcaaa gtattgaaca
     1381 ttgattgaat acttgtctgc tgcatccacc gcaatctgtt taaatggcgc attcatcgtc
     1441 atcttcaggc caatatcaag tgcaatggag gtcgtcaaat tattcagaag aagtaattct
     1501 ccttttaaat cgttcttgat ctgtgtgta
//
LOCUS       DADGKS010000230         1461 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.240, whole genome shotgun sequence.
ACCESSION   DADGKS010000230 DADGKS010000000
VERSION     DADGKS010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1461
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.240"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            102..1397
                     /locus_tag="JXV47_003167"
     CDS             102..1397
                     /locus_tag="JXV47_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAX1489127.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTFLTK"
BASE COUNT          460 a          289 c          271 g          441 t
ORIGIN      
        1 ggtgaacttc accaacatct tttttgtata aaaaaatata gaaaagacac cctgaaatcc
       61 tttagaatta atttggctac caattcatag gaggattcaa gatgtctcat actcagctta
      121 tcaaagatac cctaaatatt ctagacctaa atatctattt cgaggaaaat tgtttaacta
      181 aagaaaaata caaagggcaa atttgcttga tttacaaagg aactcttctg tacaagccag
      241 aagagtgttc ccattgtctt tgtgtcgtcc cctctaggat cattcgttgg gggacgacaa
      301 ccgttcggtt gttactgaat gatgtgtctg agtatcgcac ttatctggag ctgaagaaac
      361 aacgatttaa atgtaagtct tgccaaagaa cattcgtagc ggatacctct gttgctgaaa
      421 aacactgttt cattagtcaa aaagttcgtt ggtctgtcat tgctcgctta aaagagaata
      481 cttccatgac ggaaatcgct cgtcagaaaa atatttccac ttcttcggtc tatcgtgtca
      541 tgaagcgatt ctaccgccca ttgaatcctt tcaaacagac tttgccaaag gtcttatgct
      601 ttgatgaatt caaatcggtt cgaagtgttg ccagtgcaat gagttttatc atgatggacg
      661 gacaaagcca tgcattattg gatattgtcg aaaatcgacg cttgccttat ttagaacgct
      721 atttttctcg gttttcatta gcgactcgtg aagccgttca attgattgtt attgatatgt
      781 atgcgcctta tgtttcgttg gtgaaaaagc ttttcccgaa tgctcagttg atcatcgatc
      841 gtttccacat cgtccaacat attggcagaa ctttcttgaa tcatcgagtg aaagaaacca
      901 cggtacgact taaaggaaat tcccactctc aacgagggtt agggaaaaaa ttgaagcgct
      961 attggaaact cctacaaaaa gaagaagcaa agttaaacta tgaaaaacgg gtttggcgtg
     1021 ccagttttaa agattatttg actgaaagtg agattgccga tcgactgtta gctgcttgtc
     1081 ccaacttacg ccaaggctat cagttatacc aagacattct ttatgcggta aagaaaagag
     1141 atcagtcact atttgaggat tgtttaacta gagacattag cggtctgcca gaaacctata
     1201 caaccacttt acgaacgttt aaaaagtttc tgccacagat ccaaaatgcg cttcactaca
     1261 gctattcaaa cggaccattg gaatgcttaa acaaccacat caaagtatta aaacgcaatg
     1321 cgtacggctt tcgcaacttt tacaatttca aactacgaat tatgattcgt catggcaaaa
     1381 catttttaac caaataaaca gaacagaaag aggttttctt ctttctgttc tgtccaaatt
     1441 attctaagat ttctctttac c
//
LOCUS       DADGKS010000231         1443 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.241, whole genome shotgun sequence.
ACCESSION   DADGKS010000231 DADGKS010000000
VERSION     DADGKS010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1443
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.241"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..523
                     /locus_tag="JXV47_003168"
     CDS             <1..523
                     /locus_tag="JXV47_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489128.1"
                     /translation="FFVNPVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFT
                     PTLGVKSFNTVRFYPDIAAWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMF
                     SVTLNFEDAEKLGIDYVISKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDV
                     PQTQTQENQLVVQ"
     gene            567..>1443
                     /locus_tag="JXV47_003169"
     CDS             567..>1443
                     /locus_tag="JXV47_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HAX1489129.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKT"
BASE COUNT          424 a          237 c          298 g          484 t
ORIGIN      
        1 ctttttcgtc aatccagtcg tagaaggtac aggagcgatt tttgaaaaaa cactggcaaa
       61 agaaatccaa aaaatcgatc aacaagatcc tggtaaagtt tggttgtctg aagatgaatt
      121 atataacttc accccaacat tgggagtgaa atccttcaat acagtacgct tttatccaga
      181 tatagctgca tggaagaaaa tcgatccgaa agaagaatac gagaagtatt ataatcggta
      241 tgctcataca agagctttta tcgctaagga agatacaaag ttcattttag atcgtccaga
      301 tatgttttcg gtcacgttga attttgaaga cgcagaaaaa ttagggatcg actatgtgat
      361 cagtaaacga ccattaactg attacaacca attatatgaa gcgcagttca cgcagctata
      421 tggaccggat aaagacggtt atatgatttt taaagtagaa tatccggatt atccagatgt
      481 accacaaaca caaactcagg aaaatcagct agtcgtacag taataggcta gctgagaata
      541 atcctgaaat gttagtagaa aggagagtgg agataattca agcaatcgta caaaaatttg
      601 tcaacaaaat gagtgtcggt ttcttgcttt tgttactgac gctagtcttt tttgtttgga
      661 cagcagggtt aggttttcca gcaactttgt ttatatataa caatagttca ttacttatcg
      721 cttttagtgt ggctattttg ctcattttaa atgtttataa agcaaaaggc gtcgattttc
      781 tttatctagg tgttgcgctt gcccttttca ttttcttttc ttactttcgg gaattaagaa
      841 atgagtcttt atttggagac ttactgtttc ctttgattat tttattttgt ttagtaatta
      901 aatggatcga gtggacaaaa tgggatcgcg gtatttatct gattgtcttt tcggtcttcc
      961 tcggaatcac gttatatcgt gtatttacag agatccaagt accagaagga caaagcatct
     1021 gggctccagg caattcgctt tctgatattt ggatcaatac gaatataatc ggaagttctt
     1081 tgatgactct tgctttattg atcagtggat ttgccagttc ttttgaacga tggtatgtac
     1141 gaatcatcgg tgcagtagca gttgttgcag cttttctcgg gatttgggtc tgccaatcta
     1201 gaggtgcatt agtcgcgttg attgtttttg cgatattgga tcttttacct aaatcgttga
     1261 tgcgtgtcat tcgtgcgcca tttattgctt acacggttac gattctttta gctttgccga
     1321 tttcttatct ggcggctgtc tctgaaaaag tcaatttgtt taccggtcga gaagatattt
     1381 ggcataaatt ctatcagacg ctaggagaaa aatctgaaca aattttacta ggaatgaaaa
     1441 cat
//
LOCUS       DADGKS010000232         1438 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.242, whole genome shotgun sequence.
ACCESSION   DADGKS010000232 DADGKS010000000
VERSION     DADGKS010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1438
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.242"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..152)
                     /locus_tag="JXV47_003170"
     CDS             complement(<1..152)
                     /locus_tag="JXV47_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAX1489130.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETN"
     gene            404..865
                     /gene="mscL"
                     /locus_tag="JXV47_003171"
     CDS             404..865
                     /gene="mscL"
                     /locus_tag="JXV47_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HAX1489131.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(924..1370)
                     /locus_tag="JXV47_003172"
     CDS             complement(924..1370)
                     /locus_tag="JXV47_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1489132.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
BASE COUNT          411 a          289 c          260 g          478 t
ORIGIN      
        1 ctatttgttt ccaacatgct gctgagaagt gaacgtttcg tgatgacttc ttgttgcaga
       61 cgcgcagtaa aacggataaa aatccggatc gttttgtatt gttttgttgg taagacatga
      121 agattcacgc cttctgccaa ttgatacacc atatttatat gctccttttc acagttgatt
      181 gcccgcttac tcttttaatg ggtcaacctg ccttttttac ttattcctct gcttgaaatt
      241 tataagttca ggcaattcgc cgttttttct aaatgatgtt acactttata gtatagcata
      301 gatgtttttt atcaaaagaa acagacggct aaaagcgtat attgtttttt tattttttat
      361 ttttcgatat actaaagaca aataaaagaa gggagggtca ttcatgatca aagaattcaa
      421 agagttcatc atgcgtggag atgtcttgga tcttgctgtc ggcgttgtta ttggtagtgc
      481 gtttacaagc atcgtaaacc aagtggtgca aggcttgatc acaccactaa taggttggtt
      541 tgtcgcaatg atcacaggta cttctgattt agaaggagca ctttcaattc ttgactggtc
      601 gccgacaaaa ggcgtcacat ttgcgtttgg taacgttatt agtgctatca ttacatttct
      661 gatcactggt tttgtcttat tcttagttgt caaagcggca aaccgtgcga agaatttacg
      721 ctccaaagaa gagcaagtgg aagtggaaga aactcctact gcagaagatt atcttagtga
      781 catacgcgat cttcttgcca aacaagtggc agaagacaat acacatccag tagagcaaac
      841 aaatctttcc gatacttcta aataataaag aatctaaaaa aaagaaagcc gattttcagt
      901 gtcggctttc tttttttaga ttcttaactt gctacttgtt cctttttcat gtcgatatgt
      961 ggaatatcat cttccaaata cacatctgag attgccttga atccaaacga ctcataaaaa
     1021 gcttgtaggt attcttgtgc gccgatcacg attggttttt ctggaaaatt tttctggatc
     1081 atgttaatcg tttcttgaac aatctttctt cctaaaccat ctttacggtt gtcctgatga
     1141 acaaggacac gtccaaaatg gatactctcc gcttcttcat atactcgcgt gtaggcaagg
     1201 atcttcccat cagtatcttg aaaaaacgta tgccaagctt ctccatcaat gtcatcaact
     1261 tcttgataag gacactgttg ttccacaaca aaaactgcga ttcgttcttt gacgatcgcg
     1321 taaaactctg ctgttgacaa ttcttcaaat ttctttacct gatattccac taagcaaacg
     1381 ccccctgctt ttttattctt agcataccga ttcgcacaca aaaaagcaaa cgaacctt
//
LOCUS       DADGKS010000233         1417 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.243, whole genome shotgun sequence.
ACCESSION   DADGKS010000233 DADGKS010000000
VERSION     DADGKS010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1417
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.243"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..1020)
                     /locus_tag="JXV47_003173"
     CDS             complement(<1..1020)
                     /locus_tag="JXV47_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002403348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489133.1"
                     /translation="MVAVYEYLKKNIPGCDDNVNASNRMFFGGYKSDAVIIINEDNML
                     DITELPIDFTMTCSKNCQSDSGREYELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSD
                     MSFNEIYERLLTIDMNKLLKSSKNLRCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDI
                     SENFIGVVMLILKKDSRVETFNWLLENLDLYPTHFRKLKEESKVLFDTLESMKDKLFR
                     TIRNYLEEMRRVYDVLLSDVNFFDDSKESVTCILSGEQLAKKMSFYYGKTYDIDKCNK
                     LLSLMTFIGLIKKLDDEDVPLKMLEYLNRLKEEKALGNFNHKRSNVYRLDVFNATSVI
                     QKLNED"
BASE COUNT          444 a          279 c          166 g          528 t
ORIGIN      
        1 atcttcattc aatttttgaa tcacagaagt tgcattaaaa acgtctaatc gatagacatt
       61 gcttctctta tgattaaagt ttcctaacgc tttctcttcc tttaacctat ttaggtattc
      121 gagcatcttc aaaggaacat cttcatcatc taattttttt atcaatccta taaaagtcat
      181 aagtgatagt aacttattac atttatctat gtcataagtt ttaccatagt aaaaactcat
      241 ttttttagct aattgttccc ccgacaaaat acaagtcaca ctttccttac tatcatcaaa
      301 aaaattaaca tcagaaagca agacatcata gacacgtcgc atttcctcta gataattcct
      361 tattgtcctg aaaagtttgt ctttcattga ttcaagagtg tcaaaaagta cttttgattc
      421 ctctttcaat tttcgaaaat gtgtaggata caagtctagg ttctctaata gccaattaaa
      481 tgtttctacc cgactgtctt tctttaaaat tagcatcaca actccaataa aattttcact
      541 gatatcacaa ttactggaat gacaataaaa aatggaatgc ccagttttac tggtaaaaat
      601 actagcagag ggattatgat cgttgtgaaa cagacatctt aagtttttac ttgacttaag
      661 taatttattc atatcaatgg ttaacaatct ttcataaatc tcattaaaag acatgtcgga
      721 ggaatcaaac aggcagtctt taaaccactg tttcatttct tctttgtcgt cattttttat
      781 caacttaaca aaatcggttt cattgactag ttcatactct ctccctgaat cactttgaca
      841 atttttagaa catgtcatgg taaaatcaat cggaagctca gtaatatcta acatgttgtc
      901 ttcattaatt attatcactg catctgactt atatcctcca aaaaacattc tattcgaagc
      961 atttacattg tcatcacacc cggggatgtt ctttttcaag tattcgtaaa cagcaaccat
     1021 tttaccatag tcagtaattg cttcttttaa tagaaagaca atcttgtatt tttctagatt
     1081 ttcagagtac cgaatacttt tttgtatcgc aaacgcagaa ttatgaacta aattgataga
     1141 taaaaccttt tctacgctta agtatctact atcatcttta ctcaaatcta ctaccttccc
     1201 cttctcatct ttaacagtgt tatcgacatc cagaataatt actctggttt ccacaaaact
     1261 ctccttgtca ttgcctttat tctttgtctt gcttggaata aatgattgtg atgaatttag
     1321 tatctctaca aactcatctc ttgtaacttc tctatagtta tctaaacacc tatctcttac
     1381 atcagttttt tctttttttg taactggctt ctctaat
//
LOCUS       DADGKS010000234         1413 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.244, whole genome shotgun sequence.
ACCESSION   DADGKS010000234 DADGKS010000000
VERSION     DADGKS010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1413
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.244"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..733
                     /locus_tag="JXV47_003174"
     CDS             <1..733
                     /locus_tag="JXV47_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAX1489134.1"
                     /translation="LFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLITALLI
                     FSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPEIFVL
                     VGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIENLGL
                     AGSMNSFARNLGMVIGISLSTTVLYQAMSAKMGQRVTNYIADRPDVFLYGMKITFLGS
                     FVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            1078..1245
                     /locus_tag="JXV47_003175"
     CDS             1078..1245
                     /locus_tag="JXV47_003175"
                     /inference="COORDINATES: protein motif:HMM:NF018933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAX1489135.1"
                     /translation="MGSECGHTDGKKSFTIREWTCPICRTHHDRNVNVSINILIKGYV
                     YKHCLRKHQEP"
BASE COUNT          389 a          255 c          306 g          463 t
ORIGIN      
        1 actgttcgta atttcagtga ttgcctttgt cagcttttta aaagttgaaa agaaagcagc
       61 ctctccattg atttctttcg gtatttttaa gaacaagatt tttaccatga gcttgattac
      121 agccttgttg attttttctt ccaacttctt tgttaatgta gtgattcctt tttatctgca
      181 aaatgctcgc gggttgagtc ctagctatgc cggactgttg atgatggtct ttcccttgat
      241 gatggtcgtc ggggcgcctt taagcggata cctgaccgac cgggttggcc cggagatttt
      301 tgtattagta ggcttgggtt tattgtcggt aacccaagtc atgtatatgt ttttgtcagt
      361 ggactctcct ttgtggctgt acattgtcgc tactgccatc atgggtgccg gcaatgcctt
      421 gttccagtcc ccaaataata cgatggttat gagttctgtc actatcgaaa atttgggact
      481 ggcaggctcc atgaattcct ttgcccgaaa tttggggatg gtcatcggga tttcgctttc
      541 tacgacggtc ttatatcaag cgatgtctgc taagatgggc caacgagtaa ctaactatat
      601 cgcagatcgg ccggatgtct ttttatatgg aatgaagatt acctttttag gcagctttgt
      661 tttgtgtttt gttgcctttt tcctgactat ctggcgtatc aaaaaacaag gaggtattca
      721 gaaaaatgtc tgaaaaacca ttgttgaaga atttttggag gcctgcgtat gggtgagtgg
      781 gatttccatg gatgatggaa gatgaagtga acttctgaaa accgaaaaac tcaagtatta
      841 tcttcaaaat actagtactc aattagatgc tcgatttgat tacaagaaga ctgcgaaagc
      901 cactggcaac cgcaagctag gtatccaccg atggactacg ttttagaggc aactggttat
      961 gaatacggag ctaacgctct catctgcata agaatgcaac acccagatta tgtaaagatt
     1021 ttcgatactt ctgtcaaaaa aatcatcaag atagataaat gatttccgtc tagtcaaatt
     1081 ggttcagaat gtggacacac agatggtaag aagtcattca caattcgaga atggacttgt
     1141 cctatttgcc gtacacatca tgatcgaaac gtcaacgtta gtatcaatat tttgatcaag
     1201 ggctatgtat acaagcattg ccttagaaaa catcaagaac cttaggaaca acggggatag
     1261 attggttaat aagagatatc gctgttagta aagacatagg cttgcaagta tactctttta
     1321 tcaagaattc cgtggcttta gtcatgatag gtttaatact atgaaaattt tctttagcat
     1381 ttttgattta ggttcctttt ctaattataa taa
//
LOCUS       DADGKS010000235         1393 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.245, whole genome shotgun sequence.
ACCESSION   DADGKS010000235 DADGKS010000000
VERSION     DADGKS010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1393
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.245"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..>1393)
                     /locus_tag="JXV47_003176"
     rRNA            complement(<1..>1393)
                     /locus_tag="JXV47_003176"
                     /product="23S ribosomal RNA"
BASE COUNT          287 a          433 c          307 g          366 t
ORIGIN      
        1 gctcctctca aatttccaac gcccgcgacg gatagggacc gaactgtctc acgacgttct
       61 gaacccagct cgcgtgccgc tttaatgggc gaacagccca acccttggga ccgactacag
      121 ccccaggatg cgacgagccg acatcgaggt gccaaacctc cccgtcgatg tggactcttg
      181 ggggagataa gcctgttatc cccagggtag cttttatccg ttgagcgatg gcccttccat
      241 gcggaaccac cggatcacta agcccgactt tcgtccctgc tcgacttgtt ggtctcgcag
      301 tcaagctccc ttctgccttt acactcttcg aatgatttcc aaccattctg agggaacctt
      361 tgggcgcctc cgttaccttt taggaggcga ccgccccagt caaactgccc atctgacact
      421 gtctcccacc acgattagtg gtgcgggtta gagtggccat aacgcagggg tagtatccca
      481 ccagcgcctc catcgaaact agcgttccga tttctacggc tcctacctat cctgtacatg
      541 cggtacagac actcaatatc aaactacagt aaagctccat ggggtctttc cgtcctgtcg
      601 cgggtaacct gcatcttcac aggtactaaa atttcaccga gtctctcgtt gagacagtgc
      661 ccaaatcgtt acgcctttcg tgcgggtcgg aacttacccg acaaggaatt tcgctacctt
      721 aggaccgtta tagttacggc cgccgtttac tggggcttca attcgtacct tcgcttgcgc
      781 taagcactcc tcttaacctt ccagcaccgg gcaggcgtca gcccctatac ttcatcttac
      841 gattttgcag agacctgtgt ttttgataaa cagtcgcttg ggcctattca ctgcggctga
      901 tcgtatgatc agcacccctt ctcccgaagt tacggggtca ttttgccgag ttccttaacg
      961 agagttctct cgctcacctt aggattctct cctcgactac ctgtgtcggt ttgcggtacg
     1021 ggccgctgtt ttctcactag aagcttttct cggcagtgtg acatcaggaa cttcggtact
     1081 attatttccc tccccatcac agcttgtcct taagaaaaga agcatttgac tcctcttcag
     1141 acttactgct tggacagaca tttccgatcg tctgcattcc ttagcctcct gcgtccctcc
     1201 attgctcaaa caaaaacaac gggtacagga atatcaacct gttatccatc gcctacgcct
     1261 gtcggcctcg gcttaggtcc cgactaaccc tgggcggacg agccttcccc aggaaacctt
     1321 agtcattcgg tggacaggat tctcacctgt ctttcgctac tcataccggc attctcactt
     1381 ctaagcgctc cag
//
LOCUS       DADGKS010000236         1360 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.246, whole genome shotgun sequence.
ACCESSION   DADGKS010000236 DADGKS010000000
VERSION     DADGKS010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1360
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.246"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..63
                     /locus_tag="JXV47_003177"
     CDS             <1..63
                     /locus_tag="JXV47_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1489136.1"
                     /translation="LPKRKKIMLIEEKNADVITF"
     gene            84..719
                     /locus_tag="JXV47_003178"
     CDS             84..719
                     /locus_tag="JXV47_003178"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAX1489137.1"
                     /translation="MVRHLFVDFQWSPEKISNRLKHEHMDFSISFITIYRAICNDLFD
                     TEPLSHGNKGLIRSLHHRGKTRHTKNHVESRGKICLTHSIHGHPKSADDRSDFGHWKA
                     DIVAGKTSGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEVLNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(912..1151)
                     /locus_tag="JXV47_003179"
     CDS             complement(912..1151)
                     /locus_tag="JXV47_003179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489138.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYQFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(1175..>1360)
                     /locus_tag="JXV47_003180"
     CDS             complement(1175..>1360)
                     /locus_tag="JXV47_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-binding protein ZinT"
                     /protein_id="HAX1489139.1"
                     /translation="AGRFKYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNEMHNWPTF
                     YPASLSEHEIAQEMMAH"
BASE COUNT          462 a          257 c          240 g          401 t
ORIGIN      
        1 cttccaaagc ggaaaaaaat tatgcttatc gaagaaaaaa atgcggacgt tatcacattc
       61 taaatgatcc gtgagtttgg tcaattgttc gtcatttatt tgtcgatttt cagtggtcgc
      121 cagagaaaat ctcgaatcgt ttgaagcatg aacatatgga cttttcaatt agttttatca
      181 cgatctaccg tgcaatttgc aatgatcttt tcgatacaga acccctctca cacggcaata
      241 aaggcctgat ccgttcattg caccatcgag gaaaaacaag acatacaaaa aatcatgtcg
      301 agtctcgtgg gaagatttgc cttactcatt cgatccatgg ccatccaaaa tccgcagatg
      361 atagaagtga ttttggtcat tggaaagccg atattgtagc tggcaaaact agtggtactt
      421 gtttagtgac tttgacagac agaaaatcat gcttcctttt agcaggaaag aaggtcccca
      481 gaaagaaagc cgcttatgtg agcgagaaaa tgattgaact tttaagcagt attccaaatg
      541 aggcggtcaa aacgatcact ccagatagag gaaaagaatt ctccaatcat ttcgcagtta
      601 cagaagtatt gaataatatg cccttttatt ttccagatcc tcatgccctt ggcaacaatg
      661 aacaaattaa aatacgaata gactcattcg agaatacttg ccaaaatcga aagagatagc
      721 tacggtagat aactcaacga taaatcagat gattgaaaaa ctgaataaca gacctagaaa
      781 gtgtttagat tggagaacac cttatgaagt cttctttgat aaagtgttgc gcttgatttg
      841 acaattcaag aaataataaa aagcagatca aatccaaata agggaaaaat gatctactct
      901 ggtattatca attaattggc caagctatta tgccgttttg ctaaacgtct acttcttcca
      961 gtattgacct tgataaaaca acaatcagga tcccgtttta atactctatg aactgtgtca
     1021 atactaacat gtaaagttgc agcaatatca gctaatgtac tcccatttaa tctcatttgc
     1081 tttgcaaatt gataacgccg ataagcatca atattcttgg aatccataga caataatact
     1141 tttcttacca tgtatttcct ccaaagattg gattttaatg ggccatcatt tcttgagcaa
     1201 tctcatgctc agataatgaa gctggataga aagtaggcca attatgcatt tcattataaa
     1261 gtttttcttg actttctcca ccaaagaaaa tatggaaatg ctctgcctta cttggtgcaa
     1321 ttccatgatc gctaaattga atatatttaa aacgaccagc
//
LOCUS       DADGKS010000237         1357 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.247, whole genome shotgun sequence.
ACCESSION   DADGKS010000237 DADGKS010000000
VERSION     DADGKS010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1357
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.247"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..1163)
                     /locus_tag="JXV47_003181"
     CDS             complement(<1..1163)
                     /locus_tag="JXV47_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAX1489140.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGFIALMVVTLL
                     FPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGLRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYE"
     gene            1224..>1357
                     /locus_tag="JXV47_003182"
     CDS             1224..>1357
                     /locus_tag="JXV47_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="HAX1489141.1"
                     /translation="MKKYFIIEDNQFHSEWIIKELVNHHIENIVQLTSISQINQLIQL
                     G"
BASE COUNT          482 a          238 c          218 g          419 t
ORIGIN      
        1 ttttcgtaaa catccaacat ttttttcgca ctgtatagac ctaacccgcc atttttttta
       61 gaggtttttc ctcttttgac catctccgat agcgtcaaat tcgtcggatt tgccttgttc
      121 gctatactaa aacgtaatcc ctctttttct tccagcagat tgatcgtaat cggactctga
      181 tcggctacac gatgatcgaa tgcgttagaa ataaaaatag ataaacagcg aataaaaaca
      241 accagatcaa tcgggattgt tttcacttcg acaggaataa ctacttggat cgggattttc
      301 tccgattctg ctttttctag aaattttaaa aagacacccc tgacagctgg ggatacaata
      361 tttgttagct gttgtatttg cggtttttca aaaatagctg cagaatgatc ttctaagatt
      421 tctaaaaatt ccaacgtttc ttttttattt tcctgaagag taatttttaa tgaaaacagt
      481 agacttttat aatcatgttt gaattcctct agatgatggt aatattcttc atttatttga
      541 tacagttgaa gcgattcctg atgttgtctt tcttttactt ggaaactgat caacataatg
      601 gaaaaaaaca aagaaaaaaa actgatgact atcgacaaaa gagatagaag cagataatta
      661 gatgagcgga agtgaacact tcccaatacc aagtaaatca cgccccagct taataaaata
      721 caaatacctc caaaatagtg ttcagttgga taagtaaaaa gcaagttgag aaatctcgtc
      781 tgtttgtcta tactttttac taatagatag aaaataaatg cgataagtag tgcaaaaaaa
      841 cttgctgttc caagatgtct ctttcctaaa taatccatca gatcaaaaac cagaaaaaag
      901 ctgagtccag tgatagcaaa aaaaagatta ctgatcaaac agctgataaa caggtttttc
      961 gtagtaaaat aaaaaagaaa catcaataat aagccaacta ggtaaggaaa gctcacttta
     1021 gggataggaa ataaaagtgt caccaccatc aaagctataa aaccaaagct gttttttact
     1081 agcagttgtt tcgaaaagaa taaatagata cctaaatcta aaatcaaagt aaaggtcaaa
     1141 taaagtgtca ctgttgcgac catcttattc ctccattgtt ttgtttcaaa atgtacacat
     1201 atttttttaa taggagcctg catatgaaaa agtattttat catagaagat aaccagtttc
     1261 acagcgaatg gatcatcaaa gaattggtca atcatcatat cgagaatatc gtgcagctca
     1321 cttctatctc tcaaatcaat cagttgatcc agttggg
//
LOCUS       DADGKS010000238         1346 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.248, whole genome shotgun sequence.
ACCESSION   DADGKS010000238 DADGKS010000000
VERSION     DADGKS010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1346
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.248"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            33..>1346
                     /locus_tag="JXV47_003183"
     CDS             join(33..474,474..>1346)
                     /locus_tag="JXV47_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HAX1489142.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYFKKVRNLDSRTRF
                     EQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVKKLDKPDKYSKIKQEITAIVK
                     ESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTCQIRIKRYKSYKGTVGKIAKN
                     VLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLFNGEIISYSISTSPTYKLIEE
                     MLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENNIIQSMSRKGNCLDNSVIENF
                     FGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIKLKLNGLSPV"
BASE COUNT          564 a          173 c          235 g          374 t
ORIGIN      
        1 gactagaaat ctaattaaaa ggggtgcttt ttttgcggaa atatacattt gtttttaaga
       61 aaaaagtagt ttcagactat ttaaataacg aaggcggcta caaatatctt gcacataaat
      121 atcaaataaa tcgtacactg gttagacatt gggtaaggat ttataactat catggttggg
      181 aaggcttggt tggaggtggc aaaagctaca ctacaaaatt taaacttgat gttatagaat
      241 atatggaaac aaatggtctt tctatccaag aaactgctaa aaaatttaat atcggttcaa
      301 atagaactct aagtaaatgg atagagcaat atgaagaagg cggtgcttct tcacttgaga
      361 gccaaaaaag gggcagaaaa attagtatga attccaagct aaacattcct aaaaaactta
      421 aagatgagtc tcttgaagaa gaagttattc gtttaagagc agagaacgca tatttaaaaa
      481 agttagaaac cttgattcaa gaacaagatt tgagcaagaa gaaatcaagg ttaaaacaat
      541 ccttcagctc aaaaaagaat ttaaattgaa tctattactt tcaattgcac aattagcgaa
      601 gtcaacttat tattactggg taaaaaaatt agataagcca gataaatata gcaagataaa
      661 gcaagaaatt acagcgattg taaaagaatc aagaaactct tatggttatc gtagagtcac
      721 tttagcgtta aagatgaaag gatatacaat caatcataaa acagttagaa aattaatgtc
      781 ccaaatggga cttacctgtc aaatccgaat aaagcgatat aaatcttata aaggaacagt
      841 aggaaaaatt gccaagaatg tgttaaaacg aaatttttca gtagatacac ccaataaaaa
      901 atgggtgaca gacgtcactg aattcaagat aaaaggaaga aaaatctatc tatctcctat
      961 acttgattta tttaacggag aaataattag ttatagtata tcaactagtc caacatataa
     1021 actgattgaa gaaatgcttc aacaagcaat taaaaaaaag ggaactgagg gttcactgat
     1081 tctacattca gatcaaggat ggcagtatca gatgccacaa tatcaaaaaa aattaaaaga
     1141 gaataacatt attcaaagca tgtctagaaa aggaaattgc ttagataatt ctgtaataga
     1201 aaattttttt ggtgtgctta aatcagagtt tttttatcga gaaaaattcc gatcaattga
     1261 gatatttcaa agtaaattaa atgagtatat taggtggtat aataacaaaa ggataaaact
     1321 aaagttaaat ggactatctc cagtag
//
LOCUS       DADGKS010000239         1333 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.249, whole genome shotgun sequence.
ACCESSION   DADGKS010000239 DADGKS010000000
VERSION     DADGKS010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1333
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.249"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            51..>1333
                     /locus_tag="JXV47_003184"
     CDS             51..>1333
                     /locus_tag="JXV47_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAX1489143.1"
                     /translation="MSYSEFTKELLDILDLNLTFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTIVRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPISMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKGDRRS
                     KHLKKYWRLLQKNAWELNGQHRYWRPSFRDHLTEAEIVDRLLYYDDSLKRGYEVYQVF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYRERIFLYRGKYFKKTK"
BASE COUNT          420 a          289 c          265 g          359 t
ORIGIN      
        1 aaatccttta gaataaagtc gacgaaaacc attcaaagga gtgtttcaag atgtcctatt
       61 cagagtttac caaagagtta ctagatattc tagacctaaa tcttaccttt catgaagatg
      121 cctttcgcaa agagcgcatt aatgacgaaa catgttttgt ttttgatggc acattgacct
      181 atcaaccaga ggaatgcttc cattgccact atcaaaataa gcaaacgatc attaaatggg
      241 gctggaaaaa agtatccatc ttattgaatg atgtcagtaa ctacaagacc attgtgcgga
      301 ttaacaaaca gcgcttcaaa tgtaaacact gtggaaagac ttttttagca gaagattcag
      361 ttagcgatcg tcgctgctcc attgcccgca gagtcaaaca agccattctt gagctattaa
      421 gtgagcctat ttctatgtct ttgattgcac gtatgaagca catttctccg accactgtca
      481 ttcgaatact tcgcagcctt cggcctaaaa ccgtttcttt gaaccagccg ttaccagaag
      541 tggtgtgttt cgatgaattc aaatcggtga aaaacgtctc gggagccatg agctttgtca
      601 tgatggacgg caagacccat caactgattg atattgtgga aaatcggcaa ctcaatcctt
      661 tacgcgacta tttcttgcgc taccctagaa aagtccgtga acaagtacgt ctagtggttt
      721 cagatttcta tacaccctat cgcacattgg tgaaagagtg ttttccgaat gcccgaatcg
      781 tcgccgatcg ctttcatatt agccaacaca tcggtcgggc ctttaccaac caccgaattc
      841 aagtaatgaa gacctttaaa aaaggggatc gtcggtcgaa gcacttaaag aaatactgga
      901 gactacttca aaagaatgcg tgggaattga atggtcagca tcgctactgg cgtccgtcat
      961 ttcgagatca tctgacagaa gcggagatag tcgatcggct attatattat gatgactcct
     1021 taaagcgagg ctacgaagtc taccaggttt ttctttccgc tatcagaaga caagatgttc
     1081 ctgaattcgt cgcgctccta aaagaagact acaaggagtt gccagagcac tatcaaccag
     1141 tgttcacgac cttcaagaaa tatcgaacag aaatcaaacg agcgttgcga gttccctatt
     1201 ccaacggccc tatagaatgt ttgaacaacc atatcaaagt actaaaacga attgcctatg
     1261 gctttagaaa ctttcaaaac taccgagaac gaatcttttt atatcgagga aaatatttca
     1321 agaaaactaa gaa
//
LOCUS       DADGKS010000240         1328 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.250, whole genome shotgun sequence.
ACCESSION   DADGKS010000240 DADGKS010000000
VERSION     DADGKS010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1328
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.250"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..305
                     /locus_tag="JXV47_003185"
     CDS             <1..305
                     /locus_tag="JXV47_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
                     /protein_id="HAX1489144.1"
                     /translation="KEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKGAWKEKRWNLH
                     TDFEITDDAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFILKERRKKK"
     gene            302..1060
                     /locus_tag="JXV47_003186"
     CDS             302..1060
                     /locus_tag="JXV47_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAX1489145.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPNEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QNGTDSTGTATQVQNFVQVTDKSGIYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGTPSTISGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEGKA"
     gene            complement(1146..>1328)
                     /locus_tag="JXV47_003187"
     CDS             complement(1146..>1328)
                     /locus_tag="JXV47_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489146.1"
                     /translation="EKYAYFLLLKSYCINLSQLQKIDSAHYVLEFFNGDSLLVGRKIF
                     EKTKERFHDFQKTASS"
BASE COUNT          468 a          240 c          274 g          346 t
ORIGIN      
        1 aaaaagaaaa aatagatgta gcacccaata caaattttga tttacttgtc ccattagaag
       61 gaaaaaaatt agctccggga cattatcaag cggttgtgaa gggtgcttgg aaagaaaaac
      121 gctggaatct ccataccgat tttgaaataa ctgatgatgc agcggaccaa ttgaatgaaa
      181 aggatattga tttaaaaaat cagccagaaa catttgactg gcgatggctg atacttgttg
      241 gagtcattct tattggctta tttgctggat tatttatttt aaaagaaaga aggaaaaaga
      301 aatgaaaaaa acaattgcat taagtaccgt tctagctgga agtctattat tatgtacaca
      361 aagtgttttt gctgagaata agagctcagc cactacagaa ggaacgattt ctgtaacaaa
      421 accagatgcc gcaaatcctg aagacgttgt tccagttcct cctgttgatc caaatgatcc
      481 cgatacgccg tttacaccta acgaaccaaa tcagggaaca tccggattac tgacgattga
      541 ccaagctcca gatcttgatt ttggaacaat caagttaggt acagcaaaaa cagtatatgc
      601 tgcattacaa aacggaacgg acagtacagg gacagcaaca caagtacaga atttcgtaca
      661 agtaacggat aaaagcggaa tttatgccgg ttggaaacta tcagtcaaac gaacagaatt
      721 tattggtaca acatctgata cgaataaact aactggttca aaggtgaaat tcaaaaacgc
      781 cgtgattcga aatagcgcaa ctaatagcag tggaacgcca tctactattt ctggtactgg
      841 cgctgaagga attgagatcc cagcagatca ggcagtagat ctagtaactg caggagcaaa
      901 tgaagggatt ggcacatgga tttattcatt aggagagaat gtggaacaag ggagacaatc
      961 agtggaatta tttgttcctg tatccaatta tgccgtagac aactacgttt caacattcac
     1021 atggtcgtta acagatgctc ctacagaagg gaaagcgtaa aatcaaatca atgacttcag
     1081 ggagtggagc cgattcaagg ccaactccct gaaatctgct atgcttacgt ctcagctctt
     1141 attcatcaac tcgaagcagt tttttggaag tcatggaaac gttcctttgt cttttcaaag
     1201 atctttcgac caacgagtaa ggagtcacca ttgaaaaatt ctaacacata atgagcagaa
     1261 tcaattttct gcaattgcga taagttgata cagtaagatt ttaatagtaa aaagtaagca
     1321 tacttttc
//
LOCUS       DADGKS010000241         1302 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.251, whole genome shotgun sequence.
ACCESSION   DADGKS010000241 DADGKS010000000
VERSION     DADGKS010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1302
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.251"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            271..1146
                     /locus_tag="JXV47_003188"
     CDS             271..1146
                     /locus_tag="JXV47_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489147.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
BASE COUNT          479 a          242 c          207 g          374 t
ORIGIN      
        1 atacatcata cctcttttat caattggaac aattatttat ttctaacaaa atcacttcat
       61 ttttgtcaga taaataaaaa acaaaaaaag ttccatcttt aaaacacgct attcttttac
      121 tttttctcac attctctaag aaaagaaaag gagaatgaat ttttgacaat tcgagcaaaa
      181 gtgattatca aatatgtaaa atcagctact tttttcttaa acgtttcttt atactaaata
      241 taaataagtg tttcatgaaa ggagaactag atgaataatt ggcttgagta ttttcctgaa
      301 aacgttttgg aacgcggtta cagctatcat ctgcacggtt ttgtccgtca tttgaactat
      361 acaagcaagt acttgtccgc aacagtttct ggcacggaag attataaggt agtgatcact
      421 tgggatgaaa agaccaacat gacttgtgat tgtctatatg ccatagaagg aaaaaaatgc
      481 aaacacatgg ctgctgtctt attcgcttac gaagaacgtc caataaaaaa atccaactac
      541 tcactttccg aactctcgtc ccttgtttcc tccgctagtt cctctcttgt acgggagctt
      601 ttaacagaga ttcttataga acatccgcaa tttatcgaac gcttcaaagt taagatgcca
      661 tttcatgcaa taaattattc agataaatta acaactatca tccataaata cgatcatatt
      721 atcaagaaaa acaaaaacag gaaaacagcg aagttcatca tggagatgcg aaagttcatc
      781 caagaagcag ttgaatcgct cattcagcaa aatgcctatc ttcccgcatt cgaattgatc
      841 aatgaagtga ttgctactct cgaaacattc tattgggagc ctgaggatga acgaaccctt
      901 cttctgatag aggactgtta ttatttatgg aaagaattat tagcagaagc acctcatgca
      961 gaaaaaaggc aaatgttctc ttggttcgtc tgccaagtcg atcatactga cgcctcttat
     1021 tcaaaacgct actccataaa aatcctgaaa gaagactttc gggaaaaaga attttctaac
     1081 caaaagaaaa aaatagataa aaaaactaaa gaaacggtaa agaaagacga tttcaatgaa
     1141 aaatagcaag taaacgataa caaccatcct aaatccacaa gaaatacagc agaccttgct
     1201 ttaaaaacac gaatcatgca aaggatgaag taaagaagac ttaacgcgta cccaatatta
     1261 gtcatttgac tattaggtac gcgttttgtt ttataagtca tg
//
LOCUS       DADGKS010000242         1264 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.252, whole genome shotgun sequence.
ACCESSION   DADGKS010000242 DADGKS010000000
VERSION     DADGKS010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1264
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.252"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..228
                     /locus_tag="JXV47_003189"
     CDS             <1..228
                     /locus_tag="JXV47_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HAX1489148.1"
                     /translation="ELIGLLRLQLDLQDHYSEIIPRSITGLHRFFKIYIKGFPGANDL
                     RVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            549..>1264
                     /locus_tag="JXV47_003190"
     CDS             549..>1264
                     /locus_tag="JXV47_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HAX1489149.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQI"
BASE COUNT          417 a          224 c          273 g          350 t
ORIGIN      
        1 gaactgatcg gactacttcg tctgcaacta gatctgcaag atcattattc agaaatcatc
       61 ccgcgttcca tcacaggact acatcgtttc tttaaaatct atatcaaagg atttccagga
      121 gcaaatgact tgcgagttca gttgatgaat acgaaatcta ctgatgaagt acgagagatc
      181 ttagacacct ttgaaaaaga acatccaacg cttttcagtg aacaatgatt tcttgcttga
      241 acaccgtgaa ttagaggtcg tgaaaaagct gtcctgcatc aagtaataag aacagccaaa
      301 caaaaatagc tcctcatatt ttgtcgtttt ttgagcgaat accgagggtc agttgattga
      361 acaccgttta aaagaggttg tgacaaaagt cttgtcgcaa cctctttttt aaccaaaaaa
      421 gtgcaaatag tttactttaa gtaagagaat aattatgatg aataaaagtg gaacaaatag
      481 catactatat atattgaaat gaaaactgta tggatgctcc aacttgatga agctaaggag
      541 gaattcgtat gtcagaaaag gaattaatga aggtagtcgg tttttatgaa gggttgtcga
      601 tcgatgatcc aaaaagcttt attgatgaaa aagaacagat acctgtaccc agttcacggg
      661 atcttctggt aaaagtcaac gcagtatctg ttaatcctgt cgatacgaaa cttcgccaag
      721 ataacgggat aagaaatgct ttacgtatct tagggtttga tggagtcggg aaagttgttg
      781 ctgtaggtga tgaagtgcaa aaattttctg tcggcgatcg cgttttttac gcaggtacaa
      841 cgacaagagc aggaagcaat caagaatacc aactggttga cgaacgtatt gtcgctcttg
      901 caccaaaaaa tctttcagat gaagaagccg cagccttgcc gttgacctca ttgaccgctt
      961 atgaattgtt atttgaaaaa tttggtctga ctccagaaga aaatgccaac cgcgggaaaa
     1021 aaatcttagt gatcaacgga gctgggggcg tcggttcgat tttgaatcaa ctagcgcatt
     1081 gggctggcct agaagtctac gcgactgcaa gtccgaagaa ttttgaatgg ctgaaaaaaa
     1141 caggtgtaga ctatccaatc gattatcatc acgacttaag taaaagtttt cgtgaattag
     1201 gaatcgatca agtagagtat gtcgctgtat tattcgatat tacccgctac tttgatcaaa
     1261 tcaa
//
LOCUS       DADGKS010000243         1262 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.253, whole genome shotgun sequence.
ACCESSION   DADGKS010000243 DADGKS010000000
VERSION     DADGKS010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1262
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.253"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..690
                     /locus_tag="JXV47_003191"
     CDS             <1..690
                     /locus_tag="JXV47_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAX1489150.1"
                     /translation="NPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTA
                     GNKKGIVVVTYPDGSKEEVEVTISVEDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTV
                     TLPNGSQYHGTADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNEKDSE
                     KAVSKDNKTDNQGSKQNKNRGKSSPQKQSSKAYPKTGEIDSNIFTISGGLILLGTLGL
                     LGYKNRKKENE"
     gene            824..>1262
                     /locus_tag="JXV47_003192"
     CDS             824..>1262
                     /locus_tag="JXV47_003192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAX1489151.1"
                     /translation="MKKIVIIGSNHSGLAAARFLNLCDSNYEVILIDKKSEISYLECG
                     TSLFIKREVSNLEDLFYQNRRELNSKIKKLFLETAVDKIDIQNKKIICVKKDGTRFSQ
                     EYDKLILATGSKQIMLDVPGNNLANIFSIKNFPNAKEIFKALDD"
BASE COUNT          509 a          156 c          246 g          351 t
ORIGIN      
        1 aatcctgaag gacaaaaagt gactacagac ttaaataaag agccagacgc atctgaggga
       61 attaagaaca aagaagatct accaaaagga actacttata cttggaaaga gaaagtagat
      121 gttagtacag ctggaaacaa aaaagggatt gtagtagtaa catatccaga tggatctaaa
      181 gaagaagtag aggttactat ttctgtagaa gataaaaaag caccgaataa acctcaagtt
      241 gatcctatta cagagggtga ccaaattgtt actggtaaaa ctgaaccaaa tgcagaggtg
      301 acagttacat taccaaacgg gagtcaatac catgggacag ctgataaaaa tggtaatttt
      361 acagttaaag ttcctaaatt agaggcagga acaaaagtga tagtaactgc aactgatgaa
      421 tctggtaata ctagtgaacc tactaatgta gttgtttctt caaacgaaaa agacagtgaa
      481 aaagccgtta gtaaagataa taagactgac aatcaaggta gcaagcaaaa caaaaataga
      541 ggcaaaagca gtcctcaaaa gcagtcctca aaagcttatc ctaagacggg agagattgat
      601 agtaatatct ttactattag tggtggttta atcctgttag gaactttagg gttattaggg
      661 tataaaaatc gaaaaaaaga gaatgaatag aaaatcaatt tcttaaatct tctctgaaaa
      721 gaggaagaat ctttttcttc ctctttttgt tttttatttt gggagatagg ttgttagtta
      781 aaaatgaaga tacttttcat agaagggaaa agaatgtgat taagtgaaaa aaatagtaat
      841 tattggatca aaccattcgg ggctagctgc agctcgattt ctaaacttat gtgattcaaa
      901 ttatgaagtt attctgatag ataaaaaatc agaaattagt tacttagaat gtgggacatc
      961 gttgttcata aaaagagaag ttagcaattt agaagatctt ttttatcaaa atagaagaga
     1021 actaaattct aagataaaaa agttgttttt ggagacagca gttgacaaaa ttgatattca
     1081 aaataaaaag attatttgtg taaaaaaaga tggcacaaga ttttcccaag aatatgacaa
     1141 acttatacta gctacaggtt caaagcaaat tatgttagat gtaccgggga ataatttagc
     1201 taatattttt tcgataaaga attttccaaa tgctaaagag atttttaaag ctttagatga
     1261 ta
//
LOCUS       DADGKS010000244         1262 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.254, whole genome shotgun sequence.
ACCESSION   DADGKS010000244 DADGKS010000000
VERSION     DADGKS010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1262
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.254"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            82..>1262
                     /locus_tag="JXV47_003193"
     CDS             82..>1262
                     /locus_tag="JXV47_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HAX1489152.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     K"
BASE COUNT          421 a          247 c          241 g          353 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 at
//
LOCUS       DADGKS010000245         1219 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.255, whole genome shotgun sequence.
ACCESSION   DADGKS010000245 DADGKS010000000
VERSION     DADGKS010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.255"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..439)
                     /locus_tag="JXV47_003194"
     CDS             complement(<1..439)
                     /locus_tag="JXV47_003194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAX1489153.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSEGTIRIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVKQLKMEKYIHKKAKSYSLGMKQKLGIALALLNH"
     gene            complement(600..920)
                     /locus_tag="JXV47_003195"
     CDS             complement(600..920)
                     /locus_tag="JXV47_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HAX1489154.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGLLLISIIGIKI
                     TSGH"
BASE COUNT          392 a          240 c          206 g          381 t
ORIGIN      
        1 gatggttcag taaggcaaga gcaattccca atttttgttt cattcccagc gagtaggatt
       61 tcgctttttt gtgaatgtat ttttccatct tgagctgttt cacgatagtg tcgatagcag
      121 atacatcgtt tgtttcagag aataacttca gatgatcata acctgttaag aatggataga
      181 tacccggata ttcgatcaat gctcctactt gttctaatcc tttatgacta gagggagaaa
      241 tctcattttc accaatacgg atcgttcctt ctgagtaatg gatcagtcct aaaatagctt
      301 tcatgatcgt tgtttttcca gcgccattag gacctactaa tccaacgatt ttgccaggag
      361 ataagctaaa actgacatcg ctgagggctt gtttgtgacc aaagttcttg gataattctt
      421 ggaccgaaag acttttcaaa aatattcact ccttttctat agatagtaca agcatacacc
      481 tgatgagtag agaagtcgct aggtcattag tcttattttc ttgttttttc atagaaagag
      541 gaatatcaaa taaaaagccc cgctttttct gatcagtcct tgtctgcttg tctaagtatc
      601 tagtgaccgc tagtgatttt gatgccaatg atgctgatga gcagcaaccc gacaaagaac
      661 caagtggaaa gattcagctt atcatgaaac aagaccacac caataatgac cgaaccaact
      721 gcgccaatcc ctgtccaaat aggataagag agactcatag gcaaactttt gattgccttt
      781 gacaaaaagt aaaaactagc aatcattcca atcactgtgt aaaaagaata attgatttta
      841 gaaaaaccat cactccattt catcatcgtt gaccagaata cttccaaaat tcctgctatg
      901 attaattcca tccatgccat acatacgttc ctccttcaat ataaaaaata cacaaaaaga
      961 ggagaatcat cccttcaaag acctaatgga atgatcatcc tcttttttac tacccggtgg
     1021 cagatcgtat atctttttct gtagtatagc acacctatcc agatatcggc aatctcatac
     1081 tttttagtaa agtgtaacaa gcattgacgg atatatcgtt agcagaaaag aagatgaatg
     1141 ctttgcaatt tcatagaaag gagttgttat ttattaatca tttaaaaaaa cagtaactag
     1201 accttatttt tatatatta
//
LOCUS       DADGKS010000246         1198 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.256, whole genome shotgun sequence.
ACCESSION   DADGKS010000246 DADGKS010000000
VERSION     DADGKS010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1198
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.256"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            9..860
                     /locus_tag="JXV47_003196"
     CDS             9..860
                     /locus_tag="JXV47_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAX1489155.1"
                     /translation="MNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIAGMSL
                     MDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISRYGIQ
                     KSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQTITET
                     QREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEMLAIEE
                     HTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVYSEIW
                     IAVKAKK"
     gene            960..>1198
                     /locus_tag="JXV47_003197"
     CDS             960..>1198
                     /locus_tag="JXV47_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAX1489156.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQT"
BASE COUNT          419 a          182 c          269 g          328 t
ORIGIN      
        1 ttaaagatct gaaccaattg atcgattaca tcgaagaaca tttgacagaa ggactttcct
       61 ataaaataat agccgaaaat acaggaatct ctgaatatca attaaaacgc atctttacgt
      121 ttattgcagg gatgtcgcta atggactata tcaaaaaccg tagattggct ttggctaatc
      181 gcgatctcct agatggatca agagtgacag aaacggcgtt tagatatgga tatgaaacag
      241 tcgaaggttt ttcaagagct tttcgtgatt ggtcaggata tctgccttca gaaatcagca
      301 gatacggcat acaaaaatct tttccacgct tgacattttt tattgatgtc agaggaggaa
      361 aatcgatgga atttcgtatc gaaaagaaag aacagtttta tgtggcaggt gtggcgaaaa
      421 aagttcctgt caaatttgaa ggagtcaatc aagaaataca aaagttagcg cagacgatca
      481 cggagactca aagggaagag atgcataagt taggagattt atatccaaat caagtaatca
      541 acgtttctta tggatttgat ggagcccgct tggaagaaaa gggcagtttg atgcacatga
      601 ttggctttgc tacgacaaaa gaaaatccgt acgctgattt agaaatgctt gctatagaag
      661 aacacacttg ggccattttt cctaataaag ggccatttcc ccaaacttta caagatactt
      721 gggggaaaat ctatgcagaa tggcttcctt cttcagatta tgggttagtc gaagctcccg
      781 agatctcttt tacaaaatgg ggagaggatt tcagtaatgt ttacagtgag atttggattg
      841 cagtgaaagc aaaaaaatag ttaaaaaata aaaatatccc tagaaaaaag agcgtaatcg
      901 tgtcatttcc ctttaatttt atgtaagatg aacttaatat aatagaaagg gtgggagaaa
      961 tggcaaagta taggatcgaa gaaaaaccag attttacggt gacgggtatt ggtgtggaat
     1021 tgaagagtag caatacggat tttgtcggtt tggctgcaga gaaacaagca tttgagcaaa
     1081 aagttatcgg taatggaaca atagatgcat tgaaacaagc tgctgaaaat cattatttct
     1141 ttacagtcaa cgaaccctat aacgggaaaa tgatgtacta tgtcggtgtt caaacgag
//
LOCUS       DADGKS010000247         1156 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.257, whole genome shotgun sequence.
ACCESSION   DADGKS010000247 DADGKS010000000
VERSION     DADGKS010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1156
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.257"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..358
                     /locus_tag="JXV47_003198"
     CDS             <1..358
                     /locus_tag="JXV47_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015510350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HAX1489157.1"
                     /translation="EIDTLKTAFPMGICQITEGCIPIVLNDLARNVIATGVGGAVGGG
                     LSMFWGADSRIPASGMFAVATMTRPWAFIGALLAGSFATGITILLLKKPVDPNAEVIQ
                     EEKEEEEISWDDLTIS"
     gene            369..875
                     /locus_tag="JXV47_003199"
     CDS             369..875
                     /locus_tag="JXV47_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lyxose/D-mannose family sugar isomerase"
                     /protein_id="HAX1489158.1"
                     /translation="MDYKKRVQQMFLDSGVVLKETELERIEYTDFGLGAIETEGLNLF
                     VYENNERYCGKELVLLPYQTCPEHRHPPRDENEGKKETFRCRKGLVYLYVEGKETKKL
                     SCIIPKGQERYYTAKKEIILHAGDQYTIEQNIKHWFQAGATGAVITEFSSSSDDPSDS
                     FTNPAIYR"
BASE COUNT          391 a          180 c          261 g          324 t
ORIGIN      
        1 agaaatcgat acattgaaga ccgcttttcc tatggggatc tgtcagatca cagagggatg
       61 tatccctatc gtattgaacg acttggcacg caatgtcata gcaacgggag tcggtggggc
      121 agtcggcggt ggattgagca tgttttgggg cgcagatagc cgtattccgg catcgggaat
      181 gtttgcagtc gctacgatga ccagaccatg ggcattcatt ggtgcattgt tagctggttc
      241 ttttgctacg ggaataacta ttttattatt gaaaaaacca gttgacccaa atgcagaagt
      301 catccaagaa gaaaaagagg aagaagagat atcttgggat gacttgacaa tcagttagga
      361 ggaacagaat ggattacaag aaaagagtac aacaaatgtt cctagattca ggagtagtat
      421 tgaaagaaac agaattagaa agaatcgaat atacagattt tggattagga gcaatcgaga
      481 ctgaaggatt gaatttattt gtttatgaaa ataatgagcg atactgtggg aaagaactgg
      541 tattattgcc ttatcaaact tgtccagagc atcggcaccc acctcgagat gagaatgaag
      601 gaaaaaagga aacctttcgt tgtcgaaaag gcttagtata tctttatgtc gaaggaaaag
      661 aaacaaaaaa actttcctgt attattccaa aggggcaaga acgttactat acggcaaaaa
      721 aagaaatcat acttcacgct ggagatcagt acacgatcga acaaaatatt aaacactggt
      781 tccaggcagg tgcaacaggc gcggttatca ccgaattttc ttccagcagt gatgatccaa
      841 gtgatagttt tacgaatcca gctatttatc gttaatacaa aggtttggga acaagctgat
      901 gaaccaaaat gatcaaattt cgattatttg gttcgtcggc ttttttattt agagaaacat
      961 caggcgttgg tgaaacataa cacgagaata aaatggattt ttcattaata ggagaaacaa
     1021 gtgtgtgact atttaaataa tgcgtgttat tgacatgcag gacgaaatcc caatttcttc
     1081 tataagtaag tcgtttcaat tttatattta ctagttattt atttttttgg ttactgtaaa
     1141 atagctgaaa aattat
//
LOCUS       DADGKS010000248         1141 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.258, whole genome shotgun sequence.
ACCESSION   DADGKS010000248 DADGKS010000000
VERSION     DADGKS010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1141
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.258"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..292
                     /locus_tag="JXV47_003200"
     CDS             <1..292
                     /locus_tag="JXV47_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAX1489159.1"
                     /translation="AWQYNKEKILDAFPDLHDSYYRRLCWAYFYVLDKMVLSSSYQQI
                     PRKKTVIEFLKKNRNFILTYKGFTKSRKIAIIALSFRVDWYRKLVEQKNKKN"
     gene            337..>1141
                     /locus_tag="JXV47_003201"
     CDS             337..>1141
                     /locus_tag="JXV47_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAX1489160.1"
                     /translation="MCRISIIVPVYNVEKYLKKCVDSILGQTFTDFELLLIDDGSTDN
                     SGSICDELAKTDNRIKVIHKENGGLSDARNIGIEVAKGDFIGFIDSDDYIDEDMYAFL
                     YNNILKYDAELSMCGIYDVHKNKEIKKLTPFSQLVTKSEAIELVLDGKLVVANAVSKL
                     YKKELFENVRYPKGKIAEDAAVILKIINQCNKIHVDTSQKYYYYHRGDSITSKKFTKK
                     DFDIIDVWNENEKWIIKNYPQMYDKVHTRVCWAYFVVLDKLVLTEEKGLY"
BASE COUNT          453 a          111 c          209 g          368 t
ORIGIN      
        1 agcatggcaa tataacaaag agaagatttt agatgctttt ccagatttgc atgattccta
       61 ttatcgccga ctatgttggg catattttta cgtgttggat aaaatggttt tatcaagtag
      121 ttatcaacaa attccacgta aaaaaacagt aattgaattt ttaaagaaga acagaaattt
      181 tatattaact tataagggat tcactaaatc gcgcaaaata gctattattg ctctgagctt
      241 tagagtagat tggtatagga aattggttga acaaaaaaat aaaaaaaatt agaatgttta
      301 aattagtaaa taaaagaaaa ggaattgaaa actaaaatgt gcagaataag tataatagtt
      361 ccagtttata atgttgaaaa atatttaaaa aagtgtgtcg attcaattct aggccaaaca
      421 tttaccgatt ttgaattatt attaattgat gatggttcta cagataattc aggaagtata
      481 tgcgatgaac ttgcgaaaac agacaaccga ataaaagtga tacataagga aaatgggggt
      541 ctaagtgatg ccagaaatat tggtattgag gtagcaaagg gagattttat tgggtttata
      601 gatagtgatg attacattga tgaagatatg tatgcatttt tatataacaa tatattgaaa
      661 tatgatgcag agttatcaat gtgtggtatt tatgacgtcc ataagaataa agaaattaaa
      721 aagttaactc ctttttctca attggttact aaatctgaag caattgaatt agtattagat
      781 ggtaagctag ttgttgctaa tgcagtaagc aagctatata aaaaagaatt atttgagaat
      841 gtgagatatc caaaaggaaa aattgctgaa gacgcagcag taatactgaa aattatcaat
      901 cagtgtaata aaatccatgt tgatacttct caaaaatatt attattatca tcgtggagat
      961 agtattacta gtaaaaaatt tacaaaaaaa gattttgata taattgatgt atggaatgag
     1021 aatgaaaaat ggattattaa aaattatcct caaatgtacg ataaagtaca tactagagtt
     1081 tgttgggctt actttgttgt gttagataaa ttagttttaa ctgaagaaaa aggactgtat
     1141 c
//
LOCUS       DADGKS010000249         1129 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.259, whole genome shotgun sequence.
ACCESSION   DADGKS010000249 DADGKS010000000
VERSION     DADGKS010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1129
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.259"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..702)
                     /locus_tag="JXV47_003202"
     CDS             complement(<1..702)
                     /locus_tag="JXV47_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1489161.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLV"
     gene            complement(695..>1129)
                     /locus_tag="JXV47_003203"
     CDS             complement(695..>1129)
                     /locus_tag="JXV47_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1489162.1"
                     /translation="DIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQS
                     GELIENTSMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVN
                     GIFDQLTRQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
BASE COUNT          367 a          248 c          208 g          306 t
ORIGIN      
        1 cacaagtacg atcatcgatg ttgctactgg cacatcgatc gttccaagga atccgtaacg
       61 gaaaccggag atcatataaa cgatcggatt gacttttgaa acagcttgcc aaaagggcgg
      121 taacatagag atggcataga aaacgccacc tagataagtt aacggctgca agacaaatgt
      181 aggcacgatc gatacatcat cataagactg agcaaaaatc ccgttgagca gtcctgctaa
      241 tgaaaacaag attgccgtca tcaataatgt aatgatgacc atgaaccatg aatacacatg
      301 aagtggtaca aagaacaagg aaatgatcgt tacgagagag ccgacgagaa tactgcgacc
      361 cacaccacca atcacaaagc cccaaataat cacatgcgta ggaacaggtg ctaccaagat
      421 ttcttcgata tttttctgaa atttttgaga gaagaaggac gaagaaacat tggcatacga
      481 actagtgata gcagacatca taatcaaacc aggaacgatg aattccatat atgaaaaacc
      541 acccatgtca ccgatccgcc caccgatcat ttttccgaaa ataacaaaat acaaggatgt
      601 cgtgatcact ggcggaacca gtgtttggac ccatatacgc aaatagcggt tcgtttcctt
      661 gatagctaaa ctttttaatg cagtaaaata aagattaaac atttttctcc tccgtatgat
      721 tattttcttc tgtgattttc aagaacagtt cttctaaacg attcgactta ttcctcatag
      781 aaagaacttt gattccttgt cttgtaagct gatcgaagat tccgttcacc ccttgatttc
      841 gttcaacttc gacagcgatt gtctgctcat cttcaaatgt acaagcatat ccttcaatca
      901 caggtttggt atcatatggc gctaaatcaa agataaatgt ttcaaattgc agttttgaca
      961 gaagctcttt catacttgta ttctcgatca gttcacccga ttggatgatt ccgatgttgc
     1021 gacaaagcat ttcagcttct tctagataat gcgtcgtcaa aatgatcgtt gtaccatttt
     1081 cgttcaattc tcgtagaaac tcccacatct cgcgtctcaa ctcgatgtc
//
LOCUS       DADGKS010000250         1122 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.260, whole genome shotgun sequence.
ACCESSION   DADGKS010000250 DADGKS010000000
VERSION     DADGKS010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1122
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.260"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(92..913)
                     /locus_tag="JXV47_003204"
     CDS             complement(92..913)
                     /locus_tag="JXV47_003204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAX1489163.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(910..>1122)
                     /locus_tag="JXV47_003205"
     CDS             complement(910..>1122)
                     /locus_tag="JXV47_003205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HAX1489164.1"
                     /translation="SKNIAVWFFFGAVVMAYLELPLIAIAAVGTIIAIVIAQRDLQLK
                     NISVHAVQSDAAVNATLDQEEEDFFQ"
BASE COUNT          350 a          268 c          184 g          320 t
ORIGIN      
        1 aatgggtgtt tgggtgaata aattacttca ttaatagtca tcttttccct ccttgctaaa
       61 aaaactgcag cctagtagct gcagcttcct actatgcgat tccaagtaat gacaataaaa
      121 ttcccaagac gaccattcca aaaataattt tgatgacgcc gactttttta tctagtaatt
      181 tgaaacagct caatgttacc aataacggta caattccttt aaaaatacta tcgaggattt
      241 cttggacatt cattagttct tcgcccttca ttgaaaagct caaaacggta ttgaatttga
      301 ccatactgat cgtcattgca cctaccatga tcagacccaa gatactagca gcttttgtca
      361 gaatttcaat taacccgttc gcatacagct tttcaatata tttagagcct aatgaatagc
      421 ctaaaacgcc gccatagtat cgcatcaagt aattaggtat attgaacata actaaaaaga
      481 taattggtgc caaaatattt ccggcattgg ctaagttgat cgctagtccc gcggtaacga
      541 cacgccaaac tccccagaac aatgaatcgc caattccagc caatggtccc atcaaactcg
      601 ttttgatcgc gttgatactt tccacgtcaa aaccagcttt ttcagaattt tccttctcca
      661 tcgatgccgc aatccccatg acaaaggacg cgcaaggaat ggtcgtcgaa aaatactgtg
      721 tatgacgttc cagcgccgca gctcgatctt cttcactttt gtagaaatga ttaatgaagg
      781 gcatcataga ataggcgaaa ccaccgccgc ccatcgtcac cggattcacc gaagcataca
      841 tagtcatcga gcgccaaaac atcttccgaa ccaatttttt ctcatcttta gaaattccat
      901 cagctaattt cattgaaaga aatcctcctc ttcttggtca agcgttgcat ttacagcagc
      961 atcgctttga actgcatgaa cagatatatt ttttagttgt agatctcttt gggctataac
     1021 aattgcaata atcgttccaa ctgcggcaat tgcaatcaat ggtaactcga gatacgccat
     1081 aacaacggcc ccaaagaaaa accacacagc aatattttta ct
//
LOCUS       DADGKS010000251         1115 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.261, whole genome shotgun sequence.
ACCESSION   DADGKS010000251 DADGKS010000000
VERSION     DADGKS010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1115
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.261"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..731)
                     /locus_tag="JXV47_003206"
     CDS             complement(<1..731)
                     /locus_tag="JXV47_003206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAX1489165.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPEAINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSILLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVD"
     gene            complement(826..>1115)
                     /locus_tag="JXV47_003207"
     CDS             complement(826..>1115)
                     /locus_tag="JXV47_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489166.1"
                     /translation="IIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKR
                     YYILLLFLCFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWVFYLVKK"
BASE COUNT          349 a          234 c          174 g          358 t
ORIGIN      
        1 tcatctactc cttttaatag gtctggcaat gttttaagcg tatcgatcaa agaagaatct
       61 tttaaataaa ccaaatggag cttaccatca tccacttttg catttggaag taatgtttca
      121 aaaccgccta ctgagttagt tagtcctatc agcaagatac tgctctcaat ttcttccttc
      181 tttccatcaa cttctacgtg aaacgagtag gattgtgtgg aagctaactg tttgattcct
      241 gacatgaaat aagctagttt tccaaatttc gtcttcttct ccgcatctac atcattgatt
      301 gcttcaggga tagagccaat tgcgacgaca ttcataaaat agtcgtcatt tatttttcca
      361 atatccaatg gcttgactga ttcaatcgaa aaatgattga tcgcttcctc aggttctagc
      421 ggtatcccta atgctcgagc caagtcattc accgtaccca atgggaaaaa tccgaaattt
      481 ggccgatgtt cttgttcagc gattccactg attccttcgt tgactgttcc atctccgccc
      541 atgacaaaca cactatgata cccttccgta gccgcttcgc gagtaaagtt ttttgcatcc
      601 cctgcttttt ttgtatgcaa gacgaccact tcatcaaaca ccgattccaa ttttgctatc
      661 gctaattgct caaattcctt tgcttgttca ccgcctgaac tggggtttac cactaataaa
      721 acttttttca tcactttctt tcccttctga ttgatttctt taatataacg atagcataaa
      781 gaaaaaaatt aggctgtgat gaagtactgt tcatgaaaca ttcatttatt ttttgacaag
      841 ataaaatacc catactatga aactgaggaa aattaaaaca atgatatagg aaataaaaga
      901 aaatgatagg cattgtatac ctaataaagt aaaaatctta ggtggcagat aaaaacacaa
      961 aaatagcaag agaatgtaat agcgtttctt ccactttttg ttatcagacc ttatagcgat
     1021 cagaggaata ccaaatgcat aactgaaaaa ctcttgatgt actgttaata tgtcacgacc
     1081 ttgaataata aatgcaacaa tccccgctat aatta
//
LOCUS       DADGKS010000252         1101 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.262, whole genome shotgun sequence.
ACCESSION   DADGKS010000252 DADGKS010000000
VERSION     DADGKS010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1101
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.262"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..1014)
                     /locus_tag="JXV47_003208"
     CDS             complement(<1..1014)
                     /locus_tag="JXV47_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HAX1489167.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRT"
BASE COUNT          324 a          237 c          184 g          356 t
ORIGIN      
        1 tgtacgaatc cttcggcgga tattttcagg aaaagacaaa atttgaatag catcttcaaa
       61 gccgttttct aaaatgtcgc aagcagcact taattttgaa tcacaaccat atttttccaa
      121 gaagtgctct tttctttcac gtgtcaattc aagttcagag gctttaaaga tactcttcaa
      181 ctcgtctttt acatcagaag aaactttctt tggcagctta tcaaaaatat ttctcaaaaa
      241 gtgggcttgg catctttgcc agctcgcacc taaaaagttc ttgcgaacag ccttaactaa
      301 ccctttgtgt gcatcagaaa tgaccagttt tacaccgaac aaacctcgtt gaacgaacga
      361 ttgaaaaacg gtatcccaat tatcttccga ttcgccgtct tgaacatcaa aaccaagaat
      421 cgtacgtcgt ccatcagaat caatgccgat accaatatat acaccttttg agacaatacg
      481 atgattttcc cttactttca tatacagggc atcacacatg aaaaatggat attccgagcc
      541 ttctaggctc cggtttctcc actcaaaaac aaatggatcc aactgtttca tcagatttga
      601 aacgaatgat ttagaaacag tcgcaccatc cgttagcagt tcaactgttt tagttacttt
      661 gcgagtggag acaccagaaa tgaccatttc aatcatggca gcgatcaaag ctttttcgct
      721 tcgctgatat ctttcaaaga tagtaggact aaacttaccg tctctggttc gtggaacatg
      781 aagttctaac gtaccaattc gagttgtaaa cgaacgatcg tagtaaccat ttctttgtga
      841 ttgccgttct tctgaacgtt cataggcatt tgcctgaata tattgatttc gttgttcttc
      901 catcagctga ttaaacatga tagtcataag tgtttttgcg gtatcattcg caccgctttc
      961 gtttataatt gcttgaattt cttcgctttc aaaagtaaaa tgtacttgag tcattgatat
     1021 cagtcctatt cgagtatgtt ttctgcaaaa aacattgtac tcctaactga gatcaatggc
     1081 ttttttgatg cttcactttt a
//
LOCUS       DADGKS010000253         1081 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.263, whole genome shotgun sequence.
ACCESSION   DADGKS010000253 DADGKS010000000
VERSION     DADGKS010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1081
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.263"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            35..577
                     /locus_tag="JXV47_003209"
     CDS             35..577
                     /locus_tag="JXV47_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489168.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            667..>1081
                     /locus_tag="JXV47_003210"
     CDS             667..>1081
                     /locus_tag="JXV47_003210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HAX1489169.1"
                     /translation="MDELKRTEIQIIDKKERPKNGFVLSEKTDLENTEAFNKESVKDL
                     RKLPTKDINGKDFTSKDFEKYDLTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIV
                     GVVTDPVDDNGENKEAIEKSKLIHEKTKASYPFLMP"
BASE COUNT          457 a          114 c          214 g          296 t
ORIGIN      
        1 atatttcatc aacgtttcat aaaaggtgtg tagaatgtta ttgaaagtag ctataaaatg
       61 ctattgtgta aaaaataaag gaggaataat ttatgaaaaa atagtaccaa gaggagcatg
      121 cctattactt gcattatgtt tgagcttaag cgcagttggg tgtcaaaaaa gtaatgaaaa
      181 caataaaata aaagaaggac aatccataag ttctgaagag gaaggcatgt caattaatgc
      241 aaatggcaaa aatgaaactt ttaagccatc agattataca ttggaggcaa agaaagaata
      301 tgtttatgaa tatttagggc ttaaatttaa actctcagac aaatttagaa attatatagc
      361 tgataaaaag atagcgatgt tagatgatca aagtcctata gataaagaac taaagtatgc
      421 tattttgaca tttgagaaaa tgacagaaga acaaaagaat gcagttatag aaaagatggg
      481 cgatggatat aaaaattggc aaaatgagct tgaaagaatt gggactattg gtatatttga
      541 aaaaaataca tcagaagaaa aaaatctaaa attataaaat gtgatactca tactaaaata
      601 ggagtttcaa gtgatggaaa atacgattgc tatttaagca caaatagcgg agctgaaagt
      661 aatcttctgg atgaattaaa aagaactgag attcaaatta tagataaaaa agaacgtcct
      721 aaaaatggtt ttgtgctatc agaaaaaact gatttagaaa atacagaagc atttaacaaa
      781 gaatcggtta aagatttacg taaactacca acaaaggaca taaatggcaa ggattttaca
      841 agtaaagatt ttgagaagta tgatcttact atggtaaatg tatttgcaac ttggtgtaca
      901 gcttgtgtaa aggaaattcc tgatttggtt gaggttcaga atgaaatgaa aagcaagggt
      961 gtaaatatcg ttggagttgt tacagatcct gttgatgata acggtgaaaa caaggaagca
     1021 attgaaaagt caaagttaat acatgaaaag acaaaggctt catatccttt cttaatgcca
     1081 g
//
LOCUS       DADGKS010000254         1073 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.264, whole genome shotgun sequence.
ACCESSION   DADGKS010000254 DADGKS010000000
VERSION     DADGKS010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1073
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.264"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..256
                     /locus_tag="JXV47_003211"
     CDS             <1..256
                     /locus_tag="JXV47_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAX1489170.1"
                     /translation="AITPQHSQHLIIFVKKSVAIPTNLIESFNKQIKRYSRRKEQFQN
                     EESLERFLVSIFDTYNQKFLNRSHKGFQQVTDTLVSMFTE"
     gene            complement(547..1071)
                     /locus_tag="JXV47_003212"
     CDS             complement(547..1071)
                     /locus_tag="JXV47_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489171.1"
                     /translation="MIYKIIEDDKQTELNMCYFDREQDFFYYGGMGGGSIVPKINLVE
                     LDVNNYRELYVFNSLDVEIPMKQMKNIDIHILPSESCQIEYSIEYFYKGKNIKKCDKC
                     FESAVVKFPQFKLNPAASIQFQGHVFDVLAKDNIKKYKKGNIFHIDIQISSNLEDIKK
                     AFKIKTIGTAPNFK"
BASE COUNT          379 a          162 c          127 g          405 t
ORIGIN      
        1 agccataaca ccgcagcatt cacaacacct tataattttt gtcaaaaaaa gtgttgccat
       61 tccaaccaat ctaatcgagt ctttcaataa gcaaattaaa agatacagcc gtagaaaaga
      121 gcagtttcaa aatgaagaat cactagaacg ctttctagtc agcatttttg atacatacaa
      181 tcaaaaattt ctaaacagaa gccataaagg ttttcaacag gtaaccgata cattagtttc
      241 aatgtttact gagtaactaa ttattttgca ggaggacaat ttatttacac aaaattattg
      301 acgctccctt aacaataaat gaagactttt ttattgttaa ttgtttattt ttctattatt
      361 agatatgaaa atcgcattta gataaaatag aaaaatatga atatatttta aatattaaga
      421 tgagagtcat taacttatga tagtagtcaa tttgcttttc actaattaca aaatatgtga
      481 tataggaagt ttagttattg ttctcataat gccatcctgt ttttagatta tctagtaatt
      541 tttttgttat ttaaaattag gagcagtgcc aattgtttta attttaaagg ctttttttat
      601 atcttctaaa ttagaagata tttgtatatc aatatggaat atattacctt ttttgtattt
      661 ttttatgtta tctttagcta aaacatcaaa tacatgtcct tgaaattgta tcgaggcagc
      721 tggatttagt ttaaattgag gaaactttac cacagctgat tcaaaacact tgtcacattt
      781 ttttatattt ttacctttgt aaaaatattc gattgaatat tctatttggc acgactcact
      841 tggcagtata tgtatgtcaa tatttttcat ctgtttcata ggtatttcaa catctaaact
      901 attaaaaaca tataattccc tgtaattatt tacatctaac tctactaaat ttatctttgg
      961 aacaatagat cctccaccca ttccaccata ataaaaaaaa tcttgttctc tatcaaaata
     1021 gcacatatta agctcagttt gtttatcatc ctcaataatt ttataaatca aac
//
LOCUS       DADGKS010000255         1065 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.265, whole genome shotgun sequence.
ACCESSION   DADGKS010000255 DADGKS010000000
VERSION     DADGKS010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1065
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.265"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>1065
                     /locus_tag="JXV47_003213"
     CDS             <1..>1065
                     /locus_tag="JXV47_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HAX1489172.1"
                     /translation="RPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWL
                     SDTNKKLIQNTYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKG
                     KVFIHELAGTGHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAK
                     DELKIQIVSPGFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEY
                     SWKTEPDTSNVTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETT
                     VQSGKPTFDKPDVPLAKDAFSISDVYNKDFGNASVDANTGIVTFTPAKGVGESEPITG
                     TIPIKIVYQDGSVGTTDLAVT"
BASE COUNT          388 a          171 c          219 g          287 t
ORIGIN      
        1 cgtccagtcg ttattcgata tgttttacaa ttgactaagc cattagatga aatcttagaa
       61 gatatgaaag caacagcaca agttgaagaa aataaaccat ttggtgaaga tttcatcttt
      121 gattcttggt tgtcggatac gaataaaaaa ttaatccaga acacttatgg aacaggttat
      181 tattatttgc aagatattga tggtgatgga aaccctgacg ataaagaaga gagcggagac
      241 acgaatccat atatcgggaa acctgaatta gaagaagtat atgatgttga cacaacagtt
      301 aaggggaaag tattcatcca cgagttagcg ggaacaggtc acaaagccca acttgttgat
      361 aaagaaggta ctgtattagc agaaaaaact atcgctccaa atgaaaaaga tggggctcca
      421 atttcagata ctgtagaatt tgaatttacg ggtgtagatt caagtaaatt aatcgcgaaa
      481 gatgaattaa aaatccaaat cgtttctcca ggttttgata aaccagaaga aggttcaacc
      541 gttattaagg aatcaccaaa agcggttgat aaacaaaccg tggtagttgg atttaaacca
      601 gatgctaaag aatcaattcg gaataataaa aacttacctg aagatgcaga gtattcatgg
      661 aaaacagagc ctgatacttc taacgttact gatagtacga aaggtattgt aactgttaag
      721 atcggaaatc gaactttcga cgtggatgta gagtttgctg taaaagcttc tcaagctatg
      781 gaaaatgatg caacatacgt acctataaca acaactccag aaacgacagt tcaaagtgga
      841 aaacctacat ttgataaacc agatgttcct ttagctaaag atgccttttc aatttcagat
      901 gtctataata aggacttcgg taatgcaagt gttgatgcaa acactggtat tgttacattc
      961 actccagcta aaggtgtagg agaatcggag ccgattactg gaacaattcc tattaaaatt
     1021 gtttaccaag atggttctgt aggcacgacc gatttagcag taact
//
LOCUS       DADGKS010000256         1062 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.266, whole genome shotgun sequence.
ACCESSION   DADGKS010000256 DADGKS010000000
VERSION     DADGKS010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1062
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.266"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            4..963
                     /locus_tag="JXV47_003214"
     CDS             4..963
                     /locus_tag="JXV47_003214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAX1489173.1"
                     /translation="MNGFAYTINNEFNLGANEGSSQVANNQYILLHETANETATGRNE
                     AQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGSYANANSPVQIELQHTHDKAT
                     FEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHLWVTQNIWGDHTDPYGYLSEM
                     GVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNYAHIDQFGEIEN
                     ANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRADVNQAYNTSGNVGYHVSF
                     NMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
BASE COUNT          366 a          195 c          213 g          288 t
ORIGIN      
        1 ccaattaacg gatttgccta tactatcaac aatgaattta atttgggcgc aaatgaaggt
       61 agctcacaag tagcaaataa tcagtatatt ttactgcatg aaacggctaa tgaaacagca
      121 acaggacgca atgaagcgca gtatatgcaa cgttcatgga ctagcgctta tactgcttat
      181 attgtgggag acggcggaat tgtttatcaa gtcggtcaac ctggttatgt acagtacggt
      241 gctggttcgt atgctaatgc caacagtcct gtgcagattg agttacaaca cacacatgat
      301 aaagcaacgt ttgagaaaaa ctacaaggca tacgttgaat tggctagaga ttcagcaatg
      361 aaatatggta ttccattaac gttggacact ccttataacc aaccgggaat caaatcgcat
      421 ttatgggtaa cacaaaacat ctggggcgat catacagatc cttacggtta tctttctgaa
      481 atgggcgtaa gtaaagaaaa attagcatat gatttagctc atggatttac cgatgaaaat
      541 ccaacaactt ctgaaaacaa gcctgtcatt gatccaacac gagctggtgc agctaatcct
      601 acactgacag atggaacgaa ttacgcccac attgatcagt ttggagaaat cgaaaatgca
      661 aatttgcatg tagctggatg gcacattgct aactataaat acgagtatat cttcattatg
      721 gattacaata ctgggaaaga attagctcga gtaagagctg atggaattta tagagcagat
      781 gtaaatcaag cttataatac ttctggaaat gttggctatc atgtatcttt taacatgcgt
      841 aacttcccta ataagaaagt ctatgtcatg atgcgggcaa cgaatgatcc agagggaaac
      901 actaaaggcg gtgcgcaaga tttccatgac aaacgttggt atttaaatat tcctaaacga
      961 taaaaatagc tcctcgttga ggagcattac ataactatat tgacaactat aaaaatcatt
     1021 cgataaaata gtgatgttat cgcatatctt cactatcacc ca
//
LOCUS       DADGKS010000257         1060 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.267, whole genome shotgun sequence.
ACCESSION   DADGKS010000257 DADGKS010000000
VERSION     DADGKS010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1060
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.267"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(38..994)
                     /locus_tag="JXV47_003215"
     CDS             complement(38..994)
                     /locus_tag="JXV47_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489174.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          344 a          176 c          160 g          380 t
ORIGIN      
        1 tttagaaaaa gcagtcggac tttctaaaag aagttcacta ttcgatcctg tcgatgattt
       61 cttcaggaaa atcgtctatt tgcttgtcaa ttttgctgtc tttgtatttc tcttcttgga
      121 tagtcaacaa aatctttgta agattccccc agtctactgc tcttggcgga tcgagccaaa
      181 ccactacttg agatgcactt tcttcatata gattattcct attcgtgatt ataacatccg
      241 ggaactcagg ctttcctgcc tctatcactt ccgtgttcag attaatgtac aagcttaaat
      301 ttttcttgat aaattgatta taggcagcac cataagaaaa atcgatgatg atctttactg
      361 gttcagaaat cagttgaatg ggtatgtgat tgatcaataa taataaataa ctgaaaaaaa
      421 gaaaaaattt atcttgaagc aactctttgc gttttgacgt tagatcattt atatactcta
      481 tcaaatagca ataaaatgct ggatagtttt ctctaaaaaa agaaacatca agtggaaatt
      541 catcagcttt attaatagtg taatgcaaaa gtttaaaatg tattttggtt aactctcttc
      601 ggatcaattg gctcgtctct tctcgcaaca gattaaactg attttcaaaa ctttcaatga
      661 atcgttcatt caaccattcg attgtttcat cttcattttt tctcaagtat ttttgatcca
      721 atttatcatg aagataaagc caagagagtg tcttattgat aaaaataacg gatttttctc
      781 ctaatactcc ttttaagtgg taaaatccta tatccgaaaa aaatagcgac tgattgctag
      841 caatatctaa agaatcagct tgttcagcca acaggttgat tgctaaaaag tggaataatt
      901 tctttttttc ataagcagac agaggataat actgttttaa atcttttaac attttttctg
      961 tttttataat tataggtagc gtatacaatt ccacaaaact tatctctgtt gagttaaaaa
     1021 gattatataa aaaaagccga atgtttttag gattccctgt
//
LOCUS       DADGKS010000258         1043 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.268, whole genome shotgun sequence.
ACCESSION   DADGKS010000258 DADGKS010000000
VERSION     DADGKS010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1043
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.268"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            4..978
                     /locus_tag="JXV47_003216"
     CDS             4..978
                     /locus_tag="JXV47_003216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase family protein"
                     /protein_id="HAX1489175.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          374 a          132 c          182 g          355 t
ORIGIN      
        1 actatgtgta cgtctattac ttatgtaaca agtgatcatt attttggaag gaattttgat
       61 tatgaaatat cttacaatga agtagttact gttactccaa gaaattataa gttgaatttt
      121 cgaaaggtaa atgatttgga tactcattat gcaatgattg gtattgccgc tggtatagct
      181 gactaccctc tttattacga tgcgacaaat gaaaaaggat tgagtatggc tgggctaaat
      241 ttttctgggt atgctgatta taaagaaata caagaaggga aagacaatgt atctcctttt
      301 gaatttattc cttggatttt aggacaatgc tcaacagtag gagaagctaa aaaattgtta
      361 aaaaatatca atttagcaaa tataaattat agtgacgaac ttcctttatc ccctttacat
      421 tggctattag ctgataaaga aaaatcaatt gtcattgaaa gtatgaaaga tggacttcat
      481 atatatgata accctgtggg cgttcttacc aataatcctt catttgacta tcaattattt
      541 aatttaaaca attatcgtgt cttatcgagt gaaactccta aaaataattt ttcaaatcaa
      601 ataagtttga atgcctatag ccgcggtatg ggagggatag gcttgcctgg agatttatcc
      661 tcagtatctc gttttgttaa agcgactttt acgaagctga attctgtatc tggagattca
      721 gagtcagaaa gtattagtca atttttccat atcttaggtt cagtagaaca acaaaaaggt
      781 ttgtgtgatg taggtgatgg aaaatatgaa tatacaattt attcttcttg ttgcaatgtt
      841 gacaaaggaa tctattatta tcgaacatat gaagacagtc aaattactgc aattgatatg
      901 aataaagaag acttagatag tcataagtta attagttatc caattataga aaaacaacaa
      961 attaaatata taaattagtt aatgtgttgt gattgattat ttaatataga tataatacaa
     1021 aaaggcaaag atattttcaa aac
//
LOCUS       DADGKS010000259         1034 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.269, whole genome shotgun sequence.
ACCESSION   DADGKS010000259 DADGKS010000000
VERSION     DADGKS010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1034
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.269"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>1034
                     /locus_tag="JXV47_003217"
     rRNA            <1..>1034
                     /locus_tag="JXV47_003217"
                     /product="23S ribosomal RNA"
BASE COUNT          321 a          204 c          297 g          212 t
ORIGIN      
        1 atgggggaac ccaacatctt taataggatg ttacgattgt gtgaatacat agcacattcg
       61 aggtagacgc agagaactga aacatctaag tacctgcagg aagagaaaga aaattcgatt
      121 ccctgagtag cggcgagcga aacgggaaaa gcccaaacca gcaagcttgc ttgttggggt
      181 tgtaggactc caatatggta gttctttcag atagtcgaat gacttggaaa agtcagtcaa
      241 agagggtaaa aaccccgtag acgaaatgtg gaagacacct aggaggatcc tgagtacggc
      301 ggaacacgag aaattccgtc ggaatccggg aggaccatct cccaaggcta aatactccct
      361 agtgaccgat agtgaaccag taccgtgagg gaaaggtgaa aagcaccccg gaaggggagt
      421 gaaatagaac ctgaaaccgt gtgcctacaa caagtcaaag cccgttaatg ggtgatggcg
      481 tgccttttgt agaatgaacc ggcgagttac gattgcatgc gaggttaagt tgaagagacg
      541 gagccgcagc gaaagcgagt ctgaataggg cgtttgagta tgtagtcgta gacccgaaac
      601 catgtgatct acccatgtcc aggttgaagg tgcggtaaaa cgcactggag gaccgaaccc
      661 acgtacgttg aaaagtgcgg ggatgaggtg tgggtagcgg agaaattcca aacgaacttg
      721 gagatagctg gttctctccg aaatagcttt agggctagcc tcggaattga gaatgatgga
      781 ggtagagcac tgtttggact aggggcccat ctcgggttac cgaattcaga taaactccga
      841 atgccattca ttcatatccg ggagtcagac tgtgagtgat aagatccata gtcgaaaggg
      901 aaacagccca gaccaccagc taaggtccca aaatatatgt taagtggaaa aggatgtggg
      961 gttgcacaga caactaggat gttggcttag aagcagccac catttaaaga gtgcgtaata
     1021 gctcactagt cgag
//
LOCUS       DADGKS010000260         1022 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.270, whole genome shotgun sequence.
ACCESSION   DADGKS010000260 DADGKS010000000
VERSION     DADGKS010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1022
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.270"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(159..521)
                     /locus_tag="JXV47_003218"
     CDS             complement(159..521)
                     /locus_tag="JXV47_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HAX1489176.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGADAVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVALAFIPVVFGAVAVIMGYLYRDKDEQMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(558..772)
                     /locus_tag="JXV47_003219"
                     /pseudo
     CDS             complement(558..772)
                     /locus_tag="JXV47_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            900..>1022
                     /locus_tag="JXV47_003220"
     CDS             900..>1022
                     /locus_tag="JXV47_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1489177.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENS"
BASE COUNT          323 a          221 c          128 g          350 t
ORIGIN      
        1 gatgacttct ctaatccaga tgtacctgtc atttttgaaa aaatgatacc tataatagcc
       61 aagacaacga taactataat gataaacttc ttgttcatat ttactttatt caacttttta
      121 tctcctatct ccaaaataat ttgctcttat ccctcttatc agtacattga catccctaaa
      181 agtacaccaa agattgctcc agctacccct gctatcatca aaatcgtacc catttgttca
      241 tctttatctc gatataagta gcccataata acagcaacag caccaaatac aacaggaata
      301 aatgctaacg ctactaccat agaaatccaa ccaataatca aatacagctt ccctgtctct
      361 tgtccatgta cgatttgttc cttcatttca ttaattgtct gctcagtact tttctttact
      421 gcgtctgctc cagttgtctc atctgtttct tgtagtgctc cgcaaaactg gcaatactta
      481 ctttcatctg ttatttcttt gccacatttt ctacaataca tgtcttctcc tcctaaaaac
      541 attcaattgt ttattagtta actgtttact ttattaaata catcagaaaa cagctcattc
      601 attggtacac ttaatatctc agaaagcatc ttcatttgat agggtttagg aatcgttctc
      661 cctgtttgcc acgaacttac acattgctgt gtaacattca tttttttgct aactccgttt
      721 gagaaagtcc tttttctttt ctgtatcggc tgagattact tacttttttc atgattctcc
      781 cctcctgttt tattatatac aacaatatga tgtatttcaa ctcataaaat ataaaaaaac
      841 ttcaaatacc attacaaata caacaacttg ttgtactata ctgagatggg ggtgtattaa
      901 tgaaacagaa acaatatgca aaggtcatta gagaaaagcg aaaagctctc gggtggacac
      961 aaaaagaatt agctgaaaaa atcttctcta cacaacaggc agtagcaaga tgggaaaatt
     1021 ct
//
LOCUS       DADGKS010000261         1000 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.271, whole genome shotgun sequence.
ACCESSION   DADGKS010000261 DADGKS010000000
VERSION     DADGKS010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.271"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            369..1000
                     /locus_tag="JXV47_003221"
                     /pseudo
     CDS             369..1000
                     /locus_tag="JXV47_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          181 c          183 g          294 t
ORIGIN      
        1 tttcaaagtt agtagagaaa atgtagttat atatttaaat ttttaccaga aagaaatgaa
       61 caccttcaat tatctaaatc tcgaaaatgg ttagatgtaa tcatcaggaa aaacaatctt
      121 aaacgaatta ctattcatgg tcttagacac acacatgcta gcttgctttt agcaagctag
      181 tgcaaatatt aaagatgtgc aagagcgttt aggccactct tctattcaaa tcattatgga
      241 tctatatatt catattacag acaaaagaaa agaagaaacc gtagcgcaat tcgcaaaata
      301 taggctctat aatttatggg actgatgaat caaaattgat tcttcagtcc cattgttatt
      361 ttaggtatat gattcgtaca ttgaaagagt tgaaaaacta tcttccgaag ccgtcaaaaa
      421 ggaccctgcc aaaagtattg atggtggatg aatttcgttc gcacgcttca attgtggata
      481 aaatgagctt tatttgtgcg gatggcgaga ctggaaaact cattgatatt ttgcctacac
      541 gaaaattgtc tcgattaaca cactatttta gtcgctgtgc aaatcctgaa gcggtggaat
      601 atttagtgac agatatgaac gccgcctact tccaactgac aaaacgtgtc ttaccaaatg
      661 cgaaagtcgt cattgattgt tttcatatca tcaaacattt gaatcaggcg ttcaatgatt
      721 ttcgtgtaca agaaatgaaa agattacacc agttagggca acgacgggaa gccgagaaag
      781 tgaaaaagaa ctggcgcttt cttctaaaaa accgtcaaaa aatcaatcac tatgattaca
      841 aaacatggcg cagttttcgt gcacctaaat acccgctact cactgaagca atgatgattg
      901 atcgattgct ggcattttca acgcctttaa aggacgccta tacttttttc catgagctga
      961 ccgaagcctt tagagacaag gaatcagact tattttttac
//
LOCUS       DADGKS010000262          988 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.272, whole genome shotgun sequence.
ACCESSION   DADGKS010000262 DADGKS010000000
VERSION     DADGKS010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..988
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.272"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            447..>988
                     /locus_tag="JXV47_003222"
     CDS             447..>988
                     /locus_tag="JXV47_003222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HAX1489178.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRA"
BASE COUNT          360 a          137 c          184 g          307 t
ORIGIN      
        1 aatgctgtga aaccgatact ttataattat aaagaaggtg atttcaaatt ccgaagaagg
       61 aatttgaagt caccttttta cttatgtcac agtctcattc agtaatgcgg gataaggctc
      121 cttattccgc tatttgaata ctctgaagtt taatctaaga aagagtaata ttttgaaaac
      181 atgcttcatc gcatagaaat gaacttaatt tcagaaagaa tacatacata tctttttata
      241 tgttttcagc tgctgaatgg ttaaaaagca caaatatccg aaaaaaacat gaagaaatgt
      301 actttttttg ttgtaatgtt catgaaattc tctaagtaaa ttagttaaca taaggttagt
      361 aagattccta ttctgtgaat aatacgtatc agatttatct tttattctta ctaggaaagt
      421 aattattaag ggagttgatt tgaataatgg ttagcaagaa taataagaga gtatttctag
      481 aaaaaacaaa gaaacgagta ttgaagtaca gtatcaaaaa attaagtgtt ggggttgcat
      541 ctgttttgat tggtgttggt cttgtcttgg gaacaactga actagttaaa gcacaagatg
      601 aaatttctcc aagcagccca cttgaaacag cgataagctc cgtacaagta ggtgacaaag
      661 tagcttcggg gaatactttt caggagaatc ctggttatac gaaaaattat aacttttcgg
      721 atttacaatt tagtcctcaa gaactaactg gagacacact aaaaggcaat acaattggat
      781 ttgaagttta cggaaaacat aatattgcag catcaactaa aaactgggaa atccgtcttc
      841 aattagatga acgattagct aaatatgtag aaaaaattca ggtcgatcca aagaaaggaa
      901 ttggatcttc tagacggacc tttgtaagaa ttaatgattc gctgggtaga cctacaaata
      961 tttggaaggt caattatatt cgtgcaag
//
LOCUS       DADGKS010000263          984 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.273, whole genome shotgun sequence.
ACCESSION   DADGKS010000263 DADGKS010000000
VERSION     DADGKS010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..984
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.273"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..815)
                     /locus_tag="JXV47_003223"
     CDS             complement(<1..815)
                     /locus_tag="JXV47_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1489179.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPK"
BASE COUNT          359 a          172 c          135 g          318 t
ORIGIN      
        1 atcttgggag tggtaagaga agttataaaa aaggttatag gaactatcaa aatgcaaact
       61 atgccaaaaa atagccattg aaaaagaaca aaaggtgttt tcccactcaa agaatactta
      121 tatgcaaact tagcataatc gttaattgct ttattcaagg ctttaaatga tgttacttta
      181 gcaccaaata tctttataac ttgaattccg cggatatatt ctaccgtttc agagcttaac
      241 acatctaacg attcttgata tttttgaata aaatttgtat tctctgtcat tttctttaac
      301 aagaatacac caattactaa catggcgatt agaaccaatc caattttaaa gttaatgaaa
      361 aagcctaagg caactgataa aacaggtgtt actatggctt gagcactatc tggaatcaag
      421 tgagcaattg ccatatgtgt tttagccgcg ttgtcatcaa ttgtctttcg aatatatccc
      481 gaagaattta aatcaaaaaa acgaaaactt gcttctgtta aaccgctaat tccctttttt
      541 ctcaaattag tctctaagcg aaacccaagg atatgagaaa ataagccaga aaaaatataa
      601 aataaagctc ctaaagttaa ccaagcaaca gtttgaaccg cataactctt agctaaatat
      661 tcatctccta caataattag agactgaaga aatttgtaaa tactgtaata tccatagact
      721 gttaatacga cagaaaaatc agaaaataaa gtggctaacc atccgtagta tttcatttta
      781 gggacataac taaataattt tttgtatact ttcatttttt cctcccccgc attcaatttc
      841 ttctcttatt cgtttacaac tgttaatgct ttccgtaata gcgtaaatta gagatgtaca
      901 aacagataga aggtaaacta cgttctattt tttgtatttt tttaagactt ttcttccaat
      961 caatacacca atcatagata aact
//
LOCUS       DADGKS010000264          978 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.274, whole genome shotgun sequence.
ACCESSION   DADGKS010000264 DADGKS010000000
VERSION     DADGKS010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..978
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.274"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            141..398
                     /locus_tag="JXV47_003224"
     CDS             141..398
                     /locus_tag="JXV47_003224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489180.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(630..>978)
                     /locus_tag="JXV47_003225"
     CDS             complement(630..>978)
                     /locus_tag="JXV47_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HAX1489181.1"
                     /translation="FYNRVIGIGNIIKIVLSASIPILIDQASEHRSLLLIVSIASAII
                     TIIQSGMSAFNYQDKVQTSTELLMKIEKEKLLYITKTSPYNKTDEENFHLIVTTLQTE
                     LNDIISDFNQVNN"
BASE COUNT          374 a          122 c          132 g          350 t
ORIGIN      
        1 ttctgtccac gttcatttta ctccaaagtt ttcctcattt caaaagaaaa tcacagaata
       61 cacgaagaag cgtttctatt tgtataaact atatcaaagt tctatactta aattatcaaa
      121 taaaaaggac gtgaagataa atgtcaaatt tagaaaacaa agaagaaaaa gttgtaaaca
      181 aaattgtttc tgttgtcaat aaactggata aagagttaga cgaacttgat acgttatctg
      241 aaaatccaga aaaaaaacat aacctaaaaa aatggttagt tgaacgaaag gctattcatg
      301 aaattaaaaa agttcttcat gaagctgata aatatgaaaa atatgatgaa aaagaacttg
      361 ataaagaatt taaagaaatc aatgacttat tactataatt gatttatacg actcattttt
      421 gagtcgtcag actgcaaaca acactctaaa tttaggagtt tgtctacagt ctgaatagat
      481 tttaaattta ttgtccataa tgttattatg aatttatagc attaagaaaa gagataagac
      541 tttacatttt tttaggaatg taaagtctta tctcttttct taattgtaca attagtatta
      601 tctgcactac tttctaatta aataaatttt tagttattaa cttgattaaa atcagagata
      661 atatcattta attcagtttg aagggttgta acgattaaat ggaaattttc ttcatctgtt
      721 ttattatatg gggatgtttt cgttatatat aacaactttt ctttttcaat tttcattaat
      781 aactctgtcg aagtctgtac tttatcttga taattaaatg cagacatacc actttgtata
      841 attgtaatta ttgctgaagc aattgaaaca atcaatagta aagacctgtg ttcggaagcc
      901 tgatcaatta atattgggat actagctgat aagactattt ttataatatt tccgatacca
      961 attactctat tataaaat
//
LOCUS       DADGKS010000265          948 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.275, whole genome shotgun sequence.
ACCESSION   DADGKS010000265 DADGKS010000000
VERSION     DADGKS010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..948
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.275"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..939
                     /locus_tag="JXV47_003226"
     CDS             <1..939
                     /locus_tag="JXV47_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAX1489182.1"
                     /translation="INNEFNLGPNEGSSQVANNQYILLHETANETATGRNEAQYMKRS
                     WTSAYTAYIVGDGGIVYQVGQPGYVQYGAGSYANANSPVQIELQHTHDKATFEKNYKA
                     YVELARDSAMKYGIPLTLDTPYNQPGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKL
                     AYDLAHGFTDENPTTSDDKPVIDPTRAGAANPTLTDGTNYAHIDQFGEIENANLHVAG
                     WHIANYKYEYIFIMDYNTGKELARVKADGIYRPDVNQAYNTLGNVGYHVSFNMRNFPN
                     KKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPQR"
BASE COUNT          331 a          180 c          196 g          241 t
ORIGIN      
        1 atcaacaatg aatttaattt gggcccaaac gaaggtagct ctcaagtagc aaataatcag
       61 tacattttac tgcatgagac agctaacgaa acagcaacag ggcgcaatga agcgcagtat
      121 atgaaacgtt catggactag tgcttacact gcttatattg tgggagacgg cggaattgtt
      181 taccaagtcg gacaacctgg ttatgtacag tacggtgctg gttcgtatgc taatgctaac
      241 agtcccgtgc agattgagtt acaacacaca catgataaag caacgtttga gaaaaactac
      301 aaggcatacg ttgaattagc tagagattca gcaatgaaat atggtattcc acttacacta
      361 gacacaccgt ataatcaacc agggatcaaa tcgcatttat gggtaacaca aaatatttgg
      421 ggcgatcata cagatcctta cggttatctt tctgaaatgg gcgtaagtaa agaaaaatta
      481 gcctatgatt tggctcatgg atttaccgat gaaaatccga caacttcaga tgataaacca
      541 gtcattgatc caactcgagc aggtgctgca aatcctaccc tgacagatgg aacaaattac
      601 gcccacattg atcagttcgg agaaatcgaa aacgcaaact tacatgtggc tggttggcac
      661 atcgctaact ataaatacga gtatatcttc attatggatt acaatactgg gaaagaatta
      721 gctcgagtaa aagctgatgg aatatataga ccagatgtaa atcaagctta taatacttta
      781 ggaaatgttg gctatcatgt atcttttaac atgcgcaact tccctaataa gaaagtctat
      841 gtaatgatgc gggcaacgaa tgatccagaa gggaacacta aaggcggagc acaagatttt
      901 catgataaac gctggtattt aaatattccg caacgataaa aatagccc
//
LOCUS       DADGKS010000266          940 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.276, whole genome shotgun sequence.
ACCESSION   DADGKS010000266 DADGKS010000000
VERSION     DADGKS010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 940)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 940)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..940
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.276"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            172..459
                     /locus_tag="JXV47_003227"
                     /pseudo
     CDS             172..459
                     /locus_tag="JXV47_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            473..904
                     /locus_tag="JXV47_003228"
     CDS             473..904
                     /locus_tag="JXV47_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489183.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
BASE COUNT          358 a          135 c          197 g          250 t
ORIGIN      
        1 gctaaatact taaaaacgca tgtagaagct attgatggta aagaagcatt ggtgcagaca
       61 gatggagacc aagccattgc aggacataag aatttttcag gttctgtaac aatcaataat
      121 aaacgtgttt tgacgactga tgataacaga tatgaagtgg taaatctggt tgtcactaac
      181 ggtaatacag ggacagcaaa gctttatcgt gaaggaaaaa cagtttctat atattttgtg
      241 gctttaaacg gaaaaagtag tggcgggaat gattcggtta ttttaactgt tccagaaggc
      301 tatcggacac caattagttt tgaacaactg gttgggtcaa tagaccgttc tactttgaac
      361 agtgctcaac tatctattgg cgcagacgga gccattaaat ggagaagaaa ttcaagttat
      421 ggatcagctt attcatttgt tatcacttat tcaatttaag ggaggaaatc taatgaaagt
      481 agtttacaaa tcaatcaagc cttacggatt cgagcaaatc attttgaaca atcaagaaaa
      541 tatccctgaa aactgtacag agattaaacc accagttcct aactggagac caagatttga
      601 ttttgataaa aaacagtggg ttgagttagc tactgaagaa gagaaaaaag ggaatgctgt
      661 tgatagcgta gatgaattgg ctaatattaa ggcattatac gaaacgctga aggcagaaaa
      721 tgatgaattg aaacagctaa attctaaagc aatgctaaac aatgtagcaa tcaagcaaga
      781 aaatgtctta ttgaaagaaa agtcagaaag tttagcgcag ttgaattcaa aaacgatgct
      841 tgcttctgta caaaatacca aggaaatcga agaaatcaaa aaacaattac aaggtgggaa
      901 gtaacatgta ttcatatgaa gatatcaaac taatgtatga
//
LOCUS       DADGKS010000267          923 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.277, whole genome shotgun sequence.
ACCESSION   DADGKS010000267 DADGKS010000000
VERSION     DADGKS010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..923
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.277"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..>923)
                     /locus_tag="JXV47_003229"
     CDS             complement(<1..>923)
                     /locus_tag="JXV47_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAX1489184.1"
                     /translation="VGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKI
                     FEYAIHEQIIEEDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTEGLLATAN
                     NGYLFLDEVHRLSKENQEKLFVFIDTGNYRPVGENVNWHSAKVRFIFATTEKSEDYLL
                     DTFDRRIQISVMLPTFEDRPIRERLELIQLFFQNEADILQKDIIVSKEALSLMLSHPF
                     SGNIGKLKNIIKISCADVYSRTREEPLTIGKNEILIQLNMLESEVESLPIASLLIKKN
                     QKIKTDRIKPFDYDSILEKITQLINEGNFNE"
BASE COUNT          276 a          201 c          142 g          304 t
ORIGIN      
        1 ttttcattga aattaccttc atttatcagc tgagtaattt tttccaaaat cgaatcataa
       61 tcaaacggtt tgattcgatc cgtttttatc ttttgatttt tctttatcaa taaactagca
      121 atcggcaagc tttctacttc ggattccagc atatttaact gaatcaagat ctcatttttc
      181 ccaatcgtta atggctcttc ccgtgttcga ctgtacacat ccgcacaact gattttaatg
      241 atattcttca gcttaccaat attcccacta aagggatgag ataacattag agacaaagct
      301 tcttttgaaa caataatatc tttttgtaaa atatccgctt cattttgaaa aaataattga
      361 atcagctcta accgttctcg aatgggacga tcttcaaaag ttggcaacat aacactgatt
      421 tgaatacgtc gatcaaaggt gtctaataaa taatcttcac ttttttccgt cgtggcgaag
      481 ataaaacgaa ccttagcaga atgccagttt acattttcac cgactggacg ataatttcca
      541 gtatcaataa aaacaaagag cttttcttga ttttctttcg acaaacgatg gacctcatca
      601 agaaaaagat agccattgtt ggctgttgcc aataacccct ctgtatcctt ctcagccccc
      661 gtaaaggccc ctttcttgta tccaaacagt gttgccgaaa gcagttcggg attgtccgca
      721 taatcggcac aatttaaaat agcaaatggt gcatcttctt caataatttg ctcgtggata
      781 gcgtattcaa aaatttttgt ggctaaaaaa ctttttccaa cccccgtggc tccatttatt
      841 aatacactga gtccgttagg cggatatttg acagctgcaa tacatttttg aatgacctct
      901 ctcagacttc cgtcatgacc cac
//
LOCUS       DADGKS010000268          913 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.278, whole genome shotgun sequence.
ACCESSION   DADGKS010000268 DADGKS010000000
VERSION     DADGKS010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 913)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 913)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..913
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.278"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..183
                     /locus_tag="JXV47_003230"
     CDS             <1..183
                     /locus_tag="JXV47_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489185.1"
                     /translation="EKYAYFLLLKSYCINLSQLQKIDSAHYVLEFFNGDSLLVGRKIF
                     EKTKERFHDFQKTASS"
     gene            complement(269..>913)
                     /locus_tag="JXV47_003231"
     CDS             complement(269..>913)
                     /locus_tag="JXV47_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAX1489186.1"
                     /translation="TKPDAANPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQA
                     PDLDFGTIKLGTAKTVYAALQSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEF
                     IGTTSDTNKLTGSKVKFKNAVIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAG
                     ANEGIGTWIYSLGENVEQGRQSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
BASE COUNT          233 a          188 c          182 g          310 t
ORIGIN      
        1 gaaaagtatg cttacttttt acttttaaaa tcttactgta tcaacttatc gcaattgcag
       61 aaaattgatt ctgctcatta tgtgttagaa tttttcaacg gtgactcctt actcgttggt
      121 cgaaagatct ttgaaaagac aaaggaacgt ttccatgact tccaaaaaac tgcttcgagt
      181 tgatgaataa gagctgagac gtaagcatag cagatttcag ggagtgggcc ttgaatcggc
      241 tccactccct gaagtcgttg atatgatttt acgcttcctc ttctgtagga gcatctgtta
      301 acgaccatgt gaatgttgaa acgtagttgt ctacagcata attggataca ggaacaaata
      361 attccactga ttgtctccct tgttccacat tctctcctaa tgaataaatc catgtgccaa
      421 tcccttcatt tgctcctgca gttactagat ctactgcctg atctgctggg atttcgattc
      481 cttcagcgcc agttccagaa acggtagatg gcattccact gctattagtt gcgctatttc
      541 gaatcacggc gtttttgaat ttcacctttg aaccagttag tttattcgta tcagatgttg
      601 taccaataaa ttctgttcgt ttgactgata atttccaacc ggcataattt ccgcttttat
      661 ccgttacttg tacgaaattc tgtacttgtg tttgtgctcc agtactgtcc gttccgcttt
      721 gtaatgcagc atatactgtt tttgctgtac ctaacttgat tgttccaaaa tcaagatctg
      781 gagcttggtc aatcgtcagt aatccggatg ttccctgatt tggttcgtca ggtgtaaaag
      841 gagtatcagg atcatttgga tcaacaggag gaactggaac aacgtcttca ggatttgcag
      901 catctggttt ggt
//
LOCUS       DADGKS010000269          906 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.279, whole genome shotgun sequence.
ACCESSION   DADGKS010000269 DADGKS010000000
VERSION     DADGKS010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..906
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.279"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..767
                     /gene="tnpB"
                     /locus_tag="JXV47_003232"
     CDS             <1..767
                     /gene="tnpB"
                     /locus_tag="JXV47_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS200/IS605 family element transposase accessory
                     protein TnpB"
                     /protein_id="HAX1489187.1"
                     /translation="IKVPKLKSLVRIKLHRQPKGIIKSATISRHSSGKYYISLLCKEE
                     IIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQRKLSRRALLAKN
                     KGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDIICIEDLNTKGML
                     RNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICSECGHKDGKKSLE
                     IREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
BASE COUNT          335 a          144 c          164 g          263 t
ORIGIN      
        1 tcatcaaagt tcctaaattg aagtcattag taagaattaa gcttcataga caaccaaaag
       61 ggattatcaa atctgctaca atatcacgtc attctagcgg taaatactat atttctttgt
      121 tgtgtaaaga agaaattatc gaattaccta aaactaattc cacaattggt attgacttag
      181 gtattatgga ctttgcgatt ctttctgatg gacaaaaaat tgataataat aaattcacgt
      241 ccaaaatgga aaagaaacta aagcgtgaac aacgcaaatt gtctaggcgt gctttattgg
      301 ctaaaaataa aggtaccaat ctatttgaag ctaaaaatta tcaaaaacaa aaacgcaaag
      361 tagctagatt gcatgaaaaa gtaatgaatc aacgtactga ttttctgaat aagttgagta
      421 cagaaatgat caaaaatcac gatattatct gtattgaaga cttaaacaca aaaggtatgt
      481 tgcgaaatca taaattagct aaaagtattt ctgatgtttc ttggtcaaag tttgtgacta
      541 aattacaata caaggctgac tggtatggac gaaaaatcat caaagtagat aaatggtttc
      601 cgtctagtca gatttgttca gagtgcggac ataaagatgg caagaaatct cttgaaattc
      661 gagaatggac ttgtcctgtt tgtcatactc atcatgatcg tgatatcaat gctagtatca
      721 atattctgac cgaaggtcta agactacatt ctatgggatt ggcttagatc caatcatcaa
      781 gaaccgtagg aactacgggg atagcttggt aaataagaga caccgctgtt agtaaagaaa
      841 tacgctatca agtatgctct attcccaaga agctcccact tcaagcgtta agaaccgtca
      901 ggttta
//
LOCUS       DADGKS010000270          905 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.280, whole genome shotgun sequence.
ACCESSION   DADGKS010000270 DADGKS010000000
VERSION     DADGKS010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..905
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.280"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            1..905
                     /locus_tag="JXV47_003233"
                     /pseudo
     CDS             1..905
                     /locus_tag="JXV47_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          330 a          157 c          172 g          246 t
ORIGIN      
        1 atcttacgcc tgaacaaaaa gaattgttag aactacgtaa aagaaaccag caattagaaa
       61 tggaaaatga tattttaaag caagcagcgc tgatattcgg acgaagagac aagtaatcga
      121 tgcgaataag catctttacc ctatatcagc gatgtgcaga atattaggtc tatcacgtca
      181 gtcctattat tatcaatcaa aaccaaagaa agacgaatca gaacttgaag aagtagtcgc
      241 tgaagaattt atccgcagcc gaaaggccta cggctcaaga aaaataaaaa aagccttatc
      301 aaaacgaggc attcagatca gccgacgaaa aattagtaga atcatgaaaa atagaggatt
      361 aaaatcgagc tatactgttg cttattttaa agtacatcat tctacttgca atgaagccaa
      421 aacgacaaac gtattgaatc gtaaattctt aagagacaac ccattagaag cgatcgtaac
      481 agacttgact tatgtacgag tcgggaaaaa atggaattat gtctgtttca ttttggatct
      541 gttcaatcga gaaattctcg gctattcttg tggagaacat aaagatgccg ttctagtaaa
      601 aaaagcattt agccgtatca aacaacctct gacagaggtt gagatttttc atactgatcg
      661 tggaaaagag tttgataacc aagctattga tgaattatta acaacttttg acatcaatcg
      721 atcattgagt cataaaggct gtccttttga taatgccgta gctgaatcaa cttataagtc
      781 gttgaaagta gaatttgtct atcaatacac atttgaaacc ttacaacaat tggatttgga
      841 gttatttgac tatgtcaatt ggtggaacca ccttcggttg cacggtacac ttggctacga
      901 gacac
//
LOCUS       DADGKS010000271          839 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.281, whole genome shotgun sequence.
ACCESSION   DADGKS010000271 DADGKS010000000
VERSION     DADGKS010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..839
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.281"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..>839)
                     /locus_tag="JXV47_003234"
     CDS             complement(<1..>839)
                     /locus_tag="JXV47_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAX1489188.1"
                     /translation="HDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVSKPMAIAVTCLSG
                     LIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSSVRAHASSNG
                     IDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQEVTPFLNSIF
                     QNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVFQAAPATLGQ
                     TEGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGILDKDLFRESA
                     QYL"
BASE COUNT          252 a          180 c          143 g          264 t
ORIGIN      
        1 tcaagatatt gggcagattc tctgaataaa tctttatcta atatcccata acctaacgtt
       61 tcatcggatt catcaaaata agatcgatca aagaaattgt cataccctaa atttttatat
      121 acatgatctc tattccagaa actagctaca ttcccatgga aaacagcact tgtatagcct
      181 tctgtttgac caagggtcgc tggtgctgct tgaaagacat tatctgaccc aagttctgtg
      241 aataatgagc cttgaggtaa accaaatgtg ccagtttcca acatgttttc agcatcactt
      301 gtctttccct gtcctacttc atgaaagaaa ttgtcaaaac tgatcgttgc ttgattctgg
      361 aaaatactat ttaaaaacgg cgtgacttct tgtccgtcta ccttcatatt gatcaaaaac
      421 tgttgaaaac tttctaaatg aaggacaatc acattttttc ctttagcaat cccaaatgtt
      481 tcaggatttg gctctgcata atgtttcttt gtatagtcta aaacttcatc aattccatta
      541 ctgcttgcat gcgcgcgaac actgctagtc attcctgttt tgattccgtc ataaatagtg
      601 tacgcatcga ttcctagata tttgacaata taggaacggt caaatgtccg ctgtagcaat
      661 tggggacggt tggcttcgct caacgctaaa tttcctgaaa aaatcaatcc tgaaagacag
      721 gtaacagcga tagccatcgg tttgctgaca gggttgcttt tgataggtat tttcttgacc
      781 ttcaaccaaa ccagtagccc aatgaacaca gcgatatcca accaatagat gacatcatg
//
LOCUS       DADGKS010000272          829 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.282, whole genome shotgun sequence.
ACCESSION   DADGKS010000272 DADGKS010000000
VERSION     DADGKS010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..829
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.282"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            88..489
                     /locus_tag="JXV47_003235"
     CDS             88..489
                     /locus_tag="JXV47_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAX1489189.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            483..728
                     /locus_tag="JXV47_003236"
     CDS             483..728
                     /locus_tag="JXV47_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002412373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1489190.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
BASE COUNT          304 a          114 c          145 g          266 t
ORIGIN      
        1 ttttatgttt tttttctagt tttttcgaaa aaaaggggct ttctgattgt tgtattagtg
       61 gaaaggggga aaaaggagca tattatcatg caacaacatt acaatgacat atctatacaa
      121 caccaatttg atgcctactg taaaaaagta ttacgaaacg aagctaagtc tattcgaaaa
      181 cgaaacgcta acataaagga taatgaggaa ccattggcag attcaaatga aggcaggtat
      241 tcccaaactc attttgatga acaagatgtc tatttcttat ttggaatgga aatattaatt
      301 tcagatcaaa agttatcagc agcaattgat cagttatcgg agataagaag aaagattatc
      361 ctactttatt attttgcagg ttttaatgat gctgaaatcg gtaaaattct caatatgagc
      421 acaagtggta tctggtatca acgaaagaag gcagttgaac aattgaaaat ggggtatgac
      481 ctatggtaga taaatctaaa aagcggcagt acctattagt tccactatcc attatcttat
      541 ctgctctaga aggagatcca atttcgatca agatgatact caaacattat cattcttata
      601 tggctaagtt atgtttgaca aatggattta acgaggtagg tcaattcgtt acctatgtag
      661 atgaatatat gataagtcag ctagaaatta aattaataga agcgatctta aaatttaaaa
      721 ttaactaatt aaaaaaatcc cctttccact ttttctgttt aaaagaatct tctaatagtt
      781 aaggaattag tagattcttt taggtagaaa acctattgtt cattgaaaa
//
LOCUS       DADGKS010000273          796 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.283, whole genome shotgun sequence.
ACCESSION   DADGKS010000273 DADGKS010000000
VERSION     DADGKS010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..796
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.283"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..>796)
                     /locus_tag="JXV47_003237"
     CDS             complement(<1..>796)
                     /locus_tag="JXV47_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031600262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAX1489191.1"
                     /translation="GKVLSMYARGMSQCDIAATVEDIYGFDISHEMISDITDAVLPEL
                     EEWQARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTE
                     SKNRWMQVFDELKVRGVEDVFFISMDGVSGLKEGAKAIFPSVIVQRCIVHLVRNALRY
                     LPSKDYKEVCRDMKKFYSASSLNAAHAAFDSFQNRWSHYSGAVDVCKRNFSHVEQLFD
                     YGSAIRKIMYTTNAVESIHSSFRKVTKKGVFSNENAQTVDKVHFMDD"
BASE COUNT          243 a          170 c          148 g          235 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgcgcattc tcattagaga acactccctt
       61 ttttgtgact tttctgaagc tagagtgaat actttcaact gcattagtag tgtacatgat
      121 ttttctaatg gcgctgccat aatcaaagag ttgttcaaca tgagaaaagt ttcgtttgca
      181 tacatctact gcaccagaat aatgagacca ccgattttga aaactgtcga aggcagcgtg
      241 tgcagcgttt aaagaagaag cactgtagaa ttttttcatg tctcgacaga cttccttata
      301 atccttactt gggaggtatc gtaacgcatt tcgaacaaga tgaacaatac agcgctgcac
      361 aatgacagaa ggaaaaattg cttttgcgcc ttctttgaga ccggaaacac cgtccatcga
      421 aatgaaaaaa acatcttcta caccacgtac tttcagttca tcaaatactt gcatccagcg
      481 atttttagat tctgtttgat tgagccatag gcctaaaatc tccttgtttc ctttaagatc
      541 atagccaaga atggtgtaca cagcatattc tttagcttca tagttttcgc gtaaagtgac
      601 gtacatacaa tcaacgaata gaaatgcata acacttggct aatggccgag cttgccattc
      661 ttccaattca ggaaggacgg catccgtgat atcagaaatc atttcgtggg aaatatcaaa
      721 gccgtaaata tcttcaacgg ttgcggcgat atcgcattga ctcattcctc gtgcatacat
      781 ggaaagaacc ttacct
//
LOCUS       DADGKS010000274          787 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.284, whole genome shotgun sequence.
ACCESSION   DADGKS010000274 DADGKS010000000
VERSION     DADGKS010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..787
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.284"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..189)
                     /locus_tag="JXV47_003238"
     CDS             complement(<1..189)
                     /locus_tag="JXV47_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAX1489192.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTW"
     gene            complement(182..>787)
                     /locus_tag="JXV47_003239"
     CDS             complement(182..>787)
                     /locus_tag="JXV47_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1489193.1"
                     /translation="QRYKLLDAYSGTEGKLLLSTYPVDLILLDLMLPGLSGEALLAEI
                     RQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVTKPFDIEELLLRIGIQLRHQTSVQVK
                     DLSQRIYYKEILLDKESRDVNVNGVAVHLTGREFDLLKLFLEHPKKVFSRANLYETVW
                     QEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTVWGVGFRFD"
BASE COUNT          233 a          177 c          135 g          242 t
ORIGIN      
        1 ccatgtattc agtgcatcta ctaggtccat tagattcttt tctcgaaatt cgactgaaag
       61 acgaccacca tattcttgtc gttcagaaag agtggcgatt ttcttagtta atctcttgat
      121 ttccctttgc aggaagaaaa taaaacttcc cataaagata acaacgagaa gcaacagcca
      181 tttaatcaaa tctaaacccc actccccaca ccgtatgaat atacacagca tgtgcctttg
      241 ctagcttccc tcgaagattg gaaatatgca tattcactgt tttctcacta tcaaaatatg
      301 gttcttgcca aactgtttca taaagatttg ctcgcgaaaa tacttttttc ggatgttcta
      361 aaaaaagctt cagcagatcg aattctcttc ctgtcaaatg gacagccaca ccattcacat
      421 ttacatccct cgactctttg tccagtaaga tttccttgta atagatgcgt tgcgacagat
      481 cttttacttg gacagaagtc tgatgacgaa gttggatgcc gattcgtaac aaaagttctt
      541 cgatatcaaa tggtttcgtc acatagtcat ccgctcctgc tgccaacaag gaaactttat
      601 ctctttgatc gctttttgct gaaagaacga tgatcggaac attcgatgtc tgtcggattt
      661 ctgctaacaa tgcttcacct gaaagccctg gaagcatgag atctagaagg atcaaatcga
      721 caggatatgt gcttaacaat aattttcctt ccgtacctga ataagcatca agaagtttgt
      781 atctctg
//
LOCUS       DADGKS010000275          785 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.285, whole genome shotgun sequence.
ACCESSION   DADGKS010000275 DADGKS010000000
VERSION     DADGKS010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..785
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.285"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            22..714
                     /locus_tag="JXV47_003240"
     CDS             22..714
                     /locus_tag="JXV47_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HAX1489194.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATVATTTTTSTESKSTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNADKSAQLEAF
                     MTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEWSESGTGQA
                     DYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELK
                     NGFNQIVYGQAN"
BASE COUNT          282 a          151 c          158 g          194 t
ORIGIN      
        1 aaaaaaagga ttttagtaac aattggtcta gcttttttgt tagctggttg taccaacggg
       61 aatgaatcga aaaaagaatc aacaaaagaa acagcgaaag caacagttgc aactactaca
      121 acaactagca cagagagcaa gtcaactgca gcaagtacag aaacagcaga tacctctact
      181 tcgtcagagt cttccaaaac gactgaaaca actcaaacat ctacttcaag ttcttctgta
      241 gaggcttcat cttcctcttc agaaagcagc gaacaagttg aacaaacact gtggaatgca
      301 gacaaatccg cacaattaga ggcatttatg accaaatggg gccaaacaat gggacaacaa
      361 tacaaaagtt atacgaatca aatgagtgtg gacttatatg gtcttaaagt ccctcaagct
      421 attttgaacg gggagtggaa gatggctatt ggtggagtgc ctgtttctgc agaatggtca
      481 gaaagtggga caggtcaagc agactatcaa atcacagccg tctattccga tgcagagaca
      541 gaaccatatc tgaaaaagca cgtctatcta ttcgggtttc agcaaaatca gccaaaagta
      601 ttggtgacac aacaaaatca ggggaatccc gataattatc tttacttcaa cgagacagcg
      661 aataatgaat tgaaaaatgg ctttaatcaa atcgtttatg gacaagcaaa ttaatgagat
      721 aaacaagggg ttgtgacatg tcttttatca caaccccttg ctcagtttat ttgttagtct
      781 tttat
//
LOCUS       DADGKS010000276          771 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.286, whole genome shotgun sequence.
ACCESSION   DADGKS010000276 DADGKS010000000
VERSION     DADGKS010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.286"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            116..482
                     /gene="ssrA"
                     /locus_tag="JXV47_003241"
     tmRNA           116..482
                     /gene="ssrA"
                     /locus_tag="JXV47_003241"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT          251 a          126 c          150 g          244 t
ORIGIN      
        1 aaaggggcag ttattatata aataatggga tatgattcgc ttttttattg aatttatccc
       61 aatatatgct atactaattt tgtatgaaaa atacacgtaa cccttgttag ctaacgggga
      121 cgttacggat tcgacaggca cagtcgagct tgaattgcgt ttcgtaggtt acgtctacgt
      181 aaaaacgtta cagttaaata taactgctaa aaacgaaaac aactcttacg ctttagctgc
      241 ctaaaaacag ttagcgtaga tcctctcggc atcgcccatg tgctcgagta agggtcctaa
      301 ctttagtggg atacgtttca actttccgtc tgtaagttga aaaagagaac atcagactag
      361 cgatacagaa tgcctgtcac tcggcaagct gtaaagtgaa tccttaaatg agttgactat
      421 gaacgtagat ttttaagtgg cgatgtgttt ggacgcgggt tcgactcccg ccgtctccat
      481 atatgtatgg ttgagacaga taaacatgta tgaaaaacgt tgttaaatca acgttttttt
      541 attttggtca aggagagaaa agtagagaaa tacaaaattt tttgcattga ttttgcattc
      601 aaaaaaacat tcaaacattt agaaatcccc aatacgtatt caggaaaatc tattttaagg
      661 tttacaaaaa gaacttttgt tcgtacactc tttttgaggt gaacttttat gctgatggaa
      721 ggaaaaacac aattatggtt taagcatgtt ccttcaaata agttttttta a
//
LOCUS       DADGKS010000277          762 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.287, whole genome shotgun sequence.
ACCESSION   DADGKS010000277 DADGKS010000000
VERSION     DADGKS010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..762
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.287"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..384
                     /locus_tag="JXV47_003242"
     CDS             <1..384
                     /locus_tag="JXV47_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAX1489195.1"
                     /translation="GEGKNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKT
                     VMELILEMMGQPKDAYDHVNDRAGHDLRYAIDSTKLREELGWQPEFTNFRDGLADTIK
                     WYEEHEDWWKKEKEAVEAAYAKNGQ"
     gene            482..>762
                     /locus_tag="JXV47_003243"
     CDS             482..>762
                     /locus_tag="JXV47_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar nucleotide-binding protein"
                     /protein_id="HAX1489196.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLPYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNA"
BASE COUNT          277 a          126 c          185 g          174 t
ORIGIN      
        1 ggcgaaggaa agaatgttcg tgactggatc catacgaatg atcattcttc agcagtgtgg
       61 ctgattttga cgaaaggcag aattggcgaa acctatctga tcggtgcaga cggtgaagaa
      121 gataataaga ccgtgatgga attgatctta gaaatgatgg gccaaccaaa agacgcatac
      181 gaccatgtaa acgaccgcgc agggcacgat ttgcgttatg caatcgattc gacaaaattg
      241 cgagaagagc taggttggca gcctgagttt acgaacttcc gtgatgggtt ggctgacacg
      301 atcaaatggt acgaagaaca tgaagactgg tggaaaaaag aaaaagaggc cgttgaagca
      361 gcatatgcca aaaatggaca ataatacaga ggaaatttca ctgtattaat ggaaaaacac
      421 atgtgaggca ggcgctcgcc tgtctctttt ttaaaataaa aatcaaggag cggataacca
      481 tatgttttta ttaactggag gaaatggaca attaggtaca gaattgcgcc atttattaga
      541 tgaaaaaaat ctgccatatg tttcaacaga tgcaaaagac ttggatatca cagatgctga
      601 gaaaacaatg gcttatatta cagaattaaa acccgatgtt attttccatt gcgcagctta
      661 cacagcagta gataaagcag aagaagaagc aaaagaatta gatgagaaaa tcaatgtcga
      721 tggcacaaga aatgtagcac ttgcagcaaa agctgtgaat gc
//
LOCUS       DADGKS010000278          755 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.288, whole genome shotgun sequence.
ACCESSION   DADGKS010000278 DADGKS010000000
VERSION     DADGKS010000278.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..755
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.288"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..>755)
                     /locus_tag="JXV47_003244"
     CDS             complement(<1..>755)
                     /locus_tag="JXV47_003244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator BglG"
                     /protein_id="HAX1489197.1"
                     /translation="YTQIKNDLKGELLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAA
                     DKYSINVQYFEGFSQSSNIIISCMSGLGISDKLKDVFRHHLSDESIEVFTKDYRELRE
                     LIDQNDETYFDKTKLVITTSDLPRSFSIPNINVYDILDGDGAANLEHILSPEMKPAEF
                     NRLIQELVKFFSLEGIADRLNFLNPTIVMSEVETVISKYENYYHFTLNGRVKLNLYMH
                     TALMMERLFLARTEKSEEPNYDLKPDEDEFYYVS"
BASE COUNT          236 a          152 c          127 g          240 t
ORIGIN      
        1 gaaacataat aaaattcatc ttcatctggt ttcaaatcat aattcggttc ttcagatttt
       61 tctgtccgag ccaagaataa acgttccatc atcaatgccg tatgcatata gagatttagt
      121 tttacacggc catttaaagt gaaatgatag taattttcat atttagaaat gactgtttcc
      181 acttcactca tcacgatcgt tgggttcaga aagttcaaac ggtccgcaat tccttccaac
      241 gaaaagaatt ttactagctc ctgaatcaag cggttaaatt ctgccggctt catttcagga
      301 ctcaaaatat gctccaaatt ggctgctcca tcaccgtcta agatgtcata aacattaata
      361 ttaggaattg aaaaggaacg tggaagatcc gaagtcgtga tgaccaattt tgtcttgtca
      421 aaataagttt catcattttg gtcgattaat tcacgtagtt ctctgtagtc cttcgtgaaa
      481 acttcgatgg attcatccga taaatgatga cgaaaaacat ctttcaattt gtccgaaatc
      541 cccaaacccg acatacagga aatgataatg ttgctacttt gagaaaagcc ttcaaagtat
      601 tgaacattga ttgaatactt gtctgctgca tcctccgcaa tctgtttaaa tggcgcattc
      661 atcgtcatct tcaagccaat atcaagtgca atggaagtcg tcaaattatt cagaagaagt
      721 aactcccctt ttaaatcgtt cttgatctgt gtgta
//
LOCUS       DADGKS010000279          720 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.289, whole genome shotgun sequence.
ACCESSION   DADGKS010000279 DADGKS010000000
VERSION     DADGKS010000279.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..720
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.289"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            117..266
                     /gene="rpmG"
                     /locus_tag="JXV47_003245"
     CDS             117..266
                     /gene="rpmG"
                     /locus_tag="JXV47_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003550836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAX1489198.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            290..>720
                     /locus_tag="JXV47_003246"
     CDS             290..>720
                     /locus_tag="JXV47_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAX1489199.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREP"
BASE COUNT          264 a          111 c          144 g          201 t
ORIGIN      
        1 gttgatatga aagaaaattt agtttcacaa ttggaatctg gcgagttaac ttttgaagat
       61 gcacaacaaa ttcaagcata tcttgaagat cgataagtat tgaaggagga agatttatgc
      121 gtcaaaatat tattttggaa tgtgtcgaaa ctggagaacg tctgtatctc accagcaaaa
      181 ataaacggaa taaccctgaa cggttagaat taaaaaagta ttcgccaaaa ttgcgcagac
      241 gggcaatttt taaagaagtg aaatagctaa gtggtaaaaa ggtgacaaaa tgggcatacc
      301 agttacaatc gtttctgggt ttttaggggc tggaaaaaca acgctaatca atcaagcctt
      361 gcaagtctca ccctacccca gggaagaaat tattataatt gaaaatgagt ttggtgaagt
      421 tgggattgat cacaaattat tagttcatag cgaggaacgg gtgttacaac taaataatgg
      481 atgtatgtgt tgcagtcttc gcagtgattt attagcaata ttgatttctt tactggaaac
      541 aatagaagaa catcaacaac caatttcaca aatcatcatt gaaactacag gtatagcaga
      601 tccccaacca atcattcaaa cacttttaac agcgcctcaa ctaagaggaa gagtatatat
      661 cgatagttta ttgactgtta ttgatagtga cagttttgaa cttattgaaa gagaaccaca
//
LOCUS       DADGKS010000280          695 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.290, whole genome shotgun sequence.
ACCESSION   DADGKS010000280 DADGKS010000000
VERSION     DADGKS010000280.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..695
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.290"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..323)
                     /locus_tag="JXV47_003247"
     CDS             complement(<1..323)
                     /locus_tag="JXV47_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAX1489200.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLQLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTE"
     gene            complement(445..>695)
                     /locus_tag="JXV47_003248"
     CDS             complement(445..>695)
                     /locus_tag="JXV47_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAX1489201.1"
                     /translation="IPTITQKMLTQQLRELEQDGIVHRKVYNQVPPKVEYSLTEEGKS
                     LREILVAMSVWGEERIEKQKASGEEVTLLHTHGGYLNY"
BASE COUNT          175 a          138 c          103 g          279 t
ORIGIN      
        1 aactctgtgt atttttttcg tacacctgcg cttttttcta caggatattt caaattattt
       61 ttgatcaatt tttcttcaat gatctcatct agatccagct gaaggttgtc tgccatcatg
      121 tatgaataga tcaatacatc cgccagttct tctttgattc gttctaattg tgtttctttt
      181 acttcttccg gcgttttcca ttgaaaaagt tctaacaatt cagatgcttc caaagaaata
      241 gaaatagcca aatctttttc gttatgaaat tgtcgccaat tacgttcatc tctaaactgg
      301 ttaacttttt ccatgctatt catttgcttg ccttcttcca atcatttctt acttgattaa
      361 tcataccatt tttttacata aaaaatagat gatgctttta aaaaaactcc tgttttcttt
      421 tatttaaaat aaatgtcata gaaatcagta atttaggtag ccaccatgtg tatgcagtaa
      481 tgtgacttct tcccctgagg ctttttgttt ttcgatacgt tcttctcccc aaacagacat
      541 cgctactaga atctctctta atgattttcc ttcttcggtg agcgagtact ctactttagg
      601 cgggacttgg ttatagactt ttcgatggac aatgccatct tgttctaact ctcttaactg
      661 ctgggtcagc attttttgtg tgatcgtagg gattt
//
LOCUS       DADGKS010000281          689 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.291, whole genome shotgun sequence.
ACCESSION   DADGKS010000281 DADGKS010000000
VERSION     DADGKS010000281.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..689
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.291"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>689
                     /locus_tag="JXV47_003249"
     CDS             <1..>689
                     /locus_tag="JXV47_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HAX1489202.1"
                     /translation="VGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVNAVSVNPVDT
                     KLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAGSNQEYQLVD
                     ERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKILVINGSGGVG
                     SILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELGIDQVEYVAV
                     LFDITRYFDQI"
BASE COUNT          214 a          128 c          157 g          190 t
ORIGIN      
        1 gtcggttttt atgaagggtt gccgatcgat gatccaaaaa gctttattga tgaaaaagaa
       61 cagatacctg tacccagttc acgggatctt ctggtaaaag tcaacgcagt atctgttaat
      121 cctgtcgata cgaaacttcg ccaagataac gggataagaa atgctttacg tatcttaggt
      181 tttgatggag tcgggaaagt tgttgctgta ggtgacgaag tgcaaaaatt ttctgtcggc
      241 gatcgcgttt tttacgcagg tacaacaaca agagcaggaa gcaatcaaga ataccaacta
      301 gttgacgaac gtattgtcgc tcttgcacca aaaaatcttt cagatgaaga agctgcagcc
      361 ttgccgttga cctcattgac cgcttatgaa ttgttatttg aaaaatttgg tctaactcca
      421 gaagaaaatg ccaatcgcgg gaaaaaaatc ttagtgatca acggatccgg gggcgtcggt
      481 tcgattttga atcaactagc gcattgggct ggcctagaag tctacgcgac tgcaagtccg
      541 aagaattttg aatggctgaa aaaaacaggt gtagactatc caatcgatta tcatcacgac
      601 ttaagtaaaa gttttcgtga attaggaatc gatcaagtag agtatgtcgc tgtattattc
      661 gatattaccc gctactttga tcaaatcaa
//
LOCUS       DADGKS010000282          687 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.292, whole genome shotgun sequence.
ACCESSION   DADGKS010000282 DADGKS010000000
VERSION     DADGKS010000282.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..687
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.292"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>687
                     /locus_tag="JXV47_003250"
     CDS             <1..>687
                     /locus_tag="JXV47_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1489203.1"
                     /translation="LFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQL
                     KYGNETQIKNCDIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLI
                     SGFYNVDKGQIKIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPAS
                     KVFDALRLAGCESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDE
                     ASASIDPDNEY"
BASE COUNT          252 a           94 c          132 g          209 t
ORIGIN      
        1 ttgttttttt taagtggaat tatttttgtt tctttcatga gaataatgta tgtaagtatg
       61 cacttgtttg aagcaagata tgcagtcgaa acactagact ccctttattt agaaatgaag
      121 caagaccaac taaaatatgg gaacgagaca cagattaaaa attgtgacat tgcatttgaa
      181 aatgtcagct tttcatacaa agaagagtgt gttttagaaa atttcaactt agttttagaa
      241 caaaaaagaa tttatgcatt agtaggaaaa tcaggaagcg gaaagagtac gatagctaaa
      301 ctaatttcag gtttctacaa tgtggataag ggacagatta aaattggtgg taagccttta
      361 aatcactatt caaaagacac aattattaac acaattgctt ttgtctttca agatacgaaa
      421 ctattcaatc agagtattta cgataacgtt tctatagcaa atcctcaagc gccagcaagt
      481 aaagtatttg acgcgctaag attagccggt tgcgaatcga ttttagaaaa atttcccgaa
      541 agagagcata ccttaattgg tagtaaagga gtttatctgt caggaggaga aaaacaacgt
      601 atagctattg ccagagcaat tttaaaagat gcaaagattg ttattatgga tgaagccagt
      661 gcatctattg atccagataa tgagtat
//
LOCUS       DADGKS010000283          675 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.293, whole genome shotgun sequence.
ACCESSION   DADGKS010000283 DADGKS010000000
VERSION     DADGKS010000283.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..675
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.293"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..608
                     /locus_tag="JXV47_003251"
     CDS             <1..608
                     /locus_tag="JXV47_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489204.1"
                     /translation="ENQLFAGDVLEIVLNDQAGEAAAKGVQNKPSTNDEIGNHNPSDT
                     PVVYHDAPPFAPATKIVVEGGLSFLAPSKLDCGQIKATGLTQEAFGQMDIQEKLWIYD
                     QRETKSPWILTIKLSQPFTTDAGFSMQDVLYFKKAEEYQLVNEEELEIVRGQNSTNVQ
                     TDYSEYLNNGRAFKLVLTKENQIAGNYSAEMTWTLADAPTE"
BASE COUNT          240 a          117 c          146 g          172 t
ORIGIN      
        1 cagaaaatca actttttgca ggagatgtat tagaaattgt attaaacgac caagcaggag
       61 aagctgctgc taagggtgtg cagaacaagc caagtaccaa cgatgaaatt gggaatcaca
      121 atccaagtga tacgccagtt gtttatcatg atgccccgcc ttttgcacct gctacgaaga
      181 ttgtagtaga aggtggtctc tcatttcttg ccccttccaa actcgattgt ggtcagatca
      241 aagcaactgg gttgacgcaa gaagcatttg gccaaatgga tatacaggaa aaattatgga
      301 tttatgatca gcgagaaaca aaaagtccat ggatcttaac gataaaatta tctcagcctt
      361 tcacaaccga tgcaggattt tctatgcagg atgtcctata tttcaagaaa gctgaggagt
      421 atcaattagt gaatgaagaa gaactggaaa ttgtcagagg acaaaattca acgaatgtgc
      481 aaacagatta ttcagaatat ttaaataatg gtcgggcgtt taaacttgtc ttaaccaaag
      541 aaaatcagat agctggtaat tactcagcag agatgacatg gacattagca gatgcgccga
      601 cagaataaag atcaaggaga atgattgatg aatcgaatat ggaataaaag tcatcgaaac
      661 aactgctctt tactt
//
LOCUS       DADGKS010000284          667 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.294, whole genome shotgun sequence.
ACCESSION   DADGKS010000284 DADGKS010000000
VERSION     DADGKS010000284.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..667
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.294"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..275)
                     /locus_tag="JXV47_003252"
     CDS             complement(<1..275)
                     /locus_tag="JXV47_003252"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HAX1489205.1"
                     /translation="MISLLLVEKIASLREAFNYIQYILFTFGLLFSLLLTVANVELAT
                     IVFSSSQLAVSHETPKEIAGEDYHVFYPVTIGKNHVDFIYSNRFASAA"
     gene            complement(285..>667)
                     /locus_tag="JXV47_003253"
     CDS             complement(285..>667)
                     /locus_tag="JXV47_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HAX1489206.1"
                     /translation="ISLFTDRFNQAFHTDYATNIFEDFENSYSYSVISNTDVYNYRVY
                     LTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQVLWCLLGKKKIIITFIIAGIIGG
                     FIFMYYKEQFLYLFQMYVFLFSGI"
BASE COUNT          272 a          103 c          105 g          187 t
ORIGIN      
        1 gctgctgatg caaaacgatt ggaataaata aaatccacgt ggtttttccc gatggttact
       61 ggataaaata catgatagtc ctcaccagcg atttcttttg gtgtttcatg ggaaacagct
      121 aactgtgaag aagaaaaaac gatagttgct aattcgacat tggcaacggt caaaagaaga
      181 gaaaacaaca atccaaatgt aaaaagaatg tattggatat agttgaacgc ttctcttaac
      241 gaagcgattt tttcaactaa taaaagagaa atcaaagaga taccctatat tccgctgaac
      301 aagaaaacgt acatctggaa caaataaaga aattgctcct tataatacat aaaaataaaa
      361 ccaccaatga ttcctgcaat tatgaatgta ataatgattt tctttttccc caataaacac
      421 cacaatactt gatgtaatga aaagtcatta ttcaacaata aactgatttc tttattcatc
      481 aataagaaaa aggatgataa caaaaggaat aaaagaatca atccaatagt taaatacact
      541 cgataattat atacgtctgt atttgaaata accgaatacg aatagctatt ttcaaagtct
      601 tcaaaaatat tagtggcata atcagtgtga aatgcttgat tgaatcgatc agtgaatagt
      661 gaaatga
//
LOCUS       DADGKS010000285          653 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.295, whole genome shotgun sequence.
ACCESSION   DADGKS010000285 DADGKS010000000
VERSION     DADGKS010000285.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..653
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.295"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..189
                     /gene="rpsN"
                     /locus_tag="JXV47_003254"
     CDS             <1..189
                     /gene="rpsN"
                     /locus_tag="JXV47_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAX1489207.1"
                     /translation="KAAGDRTALAKLPRDSNPNRLRLRDQTDGRPRGYMRKFGMSRIK
                     FRELAHQGLIPGVKKASW"
     gene            204..383
                     /gene="rpmF"
                     /locus_tag="JXV47_003255"
     CDS             204..383
                     /gene="rpmF"
                     /locus_tag="JXV47_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAX1489208.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            415..>653
                     /locus_tag="JXV47_003256"
     CDS             415..>653
                     /locus_tag="JXV47_003256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489209.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEY"
BASE COUNT          236 a          101 c          144 g          172 t
ORIGIN      
        1 aaagccgcag gagatcgcac cgctctcgct aaattgccaa gagattcaaa tccgaatcgt
       61 ctgaggcttc gtgatcagac ggatggtcgt ccaagagggt atatgcgaaa gttcggtatg
      121 tcccgtatta agtttagaga acttgcccat caagggttga ttcctggagt aaaaaaagca
      181 agttggtaaa aggaggaaat atcatggcag taccagcaag aaaaacatct aaggcgaaga
      241 aacggttaag aagaactcat caaactgtag taaaaccaga aatttcattt gacgaagcga
      301 atggtgatta tagacgtagc catcatgtat ctttaaaagg gtactataat ggaaagaaag
      361 taattaaagg agcttcaaaa tagtttaata tataactttt aggagggaat caaaatggaa
      421 attatttacc cacctttagt tgaagaagga ttaaagtatt atcttgaaac gacccagcaa
      481 tcgctagata aatgcacttt ttatcgttcg atggtagaga gaggaattat tactgaaacg
      541 ggtttaccga cccaacaggc aattgaaaat ggattagtca aagattacta tgaggaccaa
      601 ggcttatcat ttgatgattt tttaagaatc tatccaattt ttgaagagta tga
//
LOCUS       DADGKS010000286          644 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.296, whole genome shotgun sequence.
ACCESSION   DADGKS010000286 DADGKS010000000
VERSION     DADGKS010000286.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..644
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.296"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..591
                     /locus_tag="JXV47_003257"
     CDS             <1..591
                     /locus_tag="JXV47_003257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAX1489210.1"
                     /translation="EKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNRMTYYVS
                     KLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLLLTLGTL
                     SVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWLMYTDFA
                     QQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
BASE COUNT          169 a          120 c          140 g          215 t
ORIGIN      
        1 gaaaaaatgg ctgcatggat tcttctggct ttcgcagcat ttgcgtgctt ttatattggg
       61 gaagaatttc aaaacggtac gattcgcaat acgttatctt taggacggaa tcgaatgact
      121 tattatgtgt cgaaacttct cgttacgctt ttgatcacaa cacttggcgt ggttttgatc
      181 acgggactag ccatgcttgc ttacacactt gctttcggat ttggtgaagt tgagggaatc
      241 aaaaactatg gaaattatgt tctaaaagta tttcctgtat tgcttctgct gacattaggg
      301 acattatctg ttccagtggc tttgacattc atcactagaa gtaccagtgt cagtttgctt
      361 ctttcttttc tttatatcat gggaacggcc ttcattcccg gtgttttcgc aaaaatcaaa
      421 ggcttggaat ttctaacgga gtggtttacg gaaacgtggc tcatgtatac ggactttgcg
      481 caacaagcaa cttattcgca agcaccgaaa atgattctgg tcagtctagt aacaatcgtg
      541 gtatcatcag ctctaggaat gtttattttc caaaaatctg acattaagta ggtggtcctg
      601 ctggaaacta ttttgattat cgaagacgat gaagctgttc attc
//
LOCUS       DADGKS010000287          637 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.297, whole genome shotgun sequence.
ACCESSION   DADGKS010000287 DADGKS010000000
VERSION     DADGKS010000287.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..637
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.297"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..521
                     /locus_tag="JXV47_003258"
     CDS             <1..521
                     /locus_tag="JXV47_003258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAX1489211.1"
                     /translation="FVSRKQNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFY
                     NLEKFNHPLVFESDSSENHYNGKHYHQHHQEHEFKSILLTSDQDIKKDFLFQLIDRLI
                     LTNQGSLYRFKGLIALQDQDFIVAIQGVNEQVNFQYTTRQKDQTTIILIGKMLDEERI
                     KQSFDKLLAESK"
     gene            551..>637
                     /locus_tag="JXV47_003259"
     CDS             551..>637
                     /locus_tag="JXV47_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAX1489212.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIK"
BASE COUNT          258 a           96 c           99 g          184 t
ORIGIN      
        1 tttttgtgtc tagaaaacaa aacttgaatt tatctgcact aaaaaaatta cagagagaaa
       61 tcaaaagtat taacccttta tccgatattc gaatgttcac acatagtgaa acgattcaaa
      121 aaaaggattt ttataatttg gaaaaattca atcatccctt agtttttgaa agtgattcat
      181 cagaaaatca ctataatggc aaacactatc atcaacatca tcaagaacat gagtttaaat
      241 caattctctt aacttcagat caagacataa aaaaagattt tttattccaa ttaattgacc
      301 ggctgatttt aaccaaccaa gggagcctgt atcgttttaa aggattgatt gctttgcaag
      361 atcaagattt tatagttgcc atacaagggg taaacgaaca ggttaatttt caatacacca
      421 ctcgacaaaa agaccaaacc actattattc taattggaaa aatgttggat gaagaaagga
      481 tcaaacagag ttttgataaa ttactggcgg aaagcaaata atgataagta ttgattaggg
      541 gtaatttcta atggagaaaa cggatatatc tagtgcatat cgacgactta aaagcccgaa
      601 tatcaaaact agaaaaaggg cattaaaaat tatcaaa
//
LOCUS       DADGKS010000288          625 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.298, whole genome shotgun sequence.
ACCESSION   DADGKS010000288 DADGKS010000000
VERSION     DADGKS010000288.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.298"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(149..511)
                     /locus_tag="JXV47_003260"
     CDS             complement(149..511)
                     /locus_tag="JXV47_003260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HAX1489213.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEKMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(548..>625)
                     /locus_tag="JXV47_003261"
     CDS             complement(548..>625)
                     /locus_tag="JXV47_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAX1489214.1"
                     /translation="MKMLSEILSVPMNELFSDVFNKVNS"
BASE COUNT          191 a          151 c           60 g          223 t
ORIGIN      
        1 ctaatccaga tgtacctgtc atttttgaaa aaataatacc tataatagcc aagacaacaa
       61 tacctataat gacaaacttc ttgttcatat ttactttatt caacttttta tctcctatct
      121 ccaaaataat ttgctcttat ccctcttatc agtacattga catccctaaa agtacaccaa
      181 agattgctcc agctacccct gctatcatca aaatcgtacc cattttctca tctttttctc
      241 gatataagta gcccataata acagcaacag caccaaatac aacaggaata aatgctaacg
      301 atactaccat agaaatccaa ccaataatca aatacagctt ccctgtctct tgtccatgta
      361 cgatttgttc cttcatttca ttaattgtct gctcagtact tttctttact gtgtctgttc
      421 cggttgtctc atctgtttct tgtagtgctc cacaaaactg gcaatactta ctttcatctg
      481 ttatttcttt gccacatttt ctacaataca tgtcttctcc tcctaaaatc attcaattgc
      541 ttattagtta actgtttact ttattaaata catcagaaaa cagctcattc attggtacac
      601 ttaatatctc agaaagcatc ttcat
//
LOCUS       DADGKS010000289          621 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.299, whole genome shotgun sequence.
ACCESSION   DADGKS010000289 DADGKS010000000
VERSION     DADGKS010000289.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..621
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.299"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..>621)
                     /locus_tag="JXV47_003262"
     CDS             complement(<1..>621)
                     /locus_tag="JXV47_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAX1489215.1"
                     /translation="FINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLMGDAI
                     SHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSSFLAL
                     GVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLITSFDP
                     LMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAAT"
BASE COUNT          262 a          112 c           73 g          174 t
ORIGIN      
        1 gtagcagctg gtgtaattaa cattgcaaca attaatatag ttcccacact ttgcatagct
       61 gttactgcta ctaaagttaa tagaatcatt aatagataat gataaaaact gacattcatc
      121 cccattgctt ttgccattaa tggatcaaaa gaagtgatta ataattcttt aaaaaataga
      181 acaactgtaa ccaacactaa aacagaaacg ccaattgtaa tccacttatc aatatcttgt
      241 acagctaaaa tatttccaaa taagatatga aataaatccg ttgagctatt tgcaactcct
      301 ataaggataa ctcctaatgc taaaaaagaa ctgaaagtaa taccaattgc tgtatctcct
      361 tttattacac tattgctttt tataaaagta ataatgatag aagctaatag accaaataca
      421 atcgcaccaa taaaaaaatt aatacctaaa atataagaaa ttgctactcc tggcaaaaca
      481 gcatgagaaa tagcatcacc cataagagac attcctctta aaataataaa acaacctact
      541 gttccagaaa caatccctat aactacagat gtaattagag cattctgtaa aaagtgaaag
      601 tcatacagac cattaataaa a
//
LOCUS       DADGKS010000290          609 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.300, whole genome shotgun sequence.
ACCESSION   DADGKS010000290 DADGKS010000000
VERSION     DADGKS010000290.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..609
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.300"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..308)
                     /locus_tag="JXV47_003263"
     CDS             complement(<1..308)
                     /locus_tag="JXV47_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HAX1489216.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SVEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAVEPLLQNVEKYHKIYQQCRKI
                     "
     gene            394..>609
                     /locus_tag="JXV47_003264"
     CDS             394..>609
                     /locus_tag="JXV47_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HAX1489217.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIV"
BASE COUNT          164 a          135 c          112 g          198 t
ORIGIN      
        1 tagattttcc ggcattgttg atagatttta tgatactttt ctacattttg taagagaggt
       61 tccactgcat ctgtatattg gataaaattc tgacaacaac tttcaggtgt gtcgaaccac
      121 cctaacccta gtgcagcaat cattgttgcg cctaatgcag gtccttcctc cacacttaaa
      181 caatagaccg ttgcatcgaa aatatcagct tggatttgta gccatgcaag atttttcgcg
      241 cctcctccca ccgaaacaat acgtgtaaat ctgcgacccg ctagttcttt acgtttcaat
      301 cccaccattg acaaatgctc attaaaaatt tagaatattc acaagtttaa cgacaattat
      361 gaaaatttat gtcgtgctaa aggagttttg ttattggatg aaaagttaga tataaaaact
      421 gcgatcaaag acacgttacc taccgttttc ggttatatcg gtattggact tgcatttggt
      481 atcgttggga aagctgccgg atttcatcca ctagtcgtca cgttgatgtc cctgctggtc
      541 tatgctggtt ctgcccaatt tatcacagtc agcatgcttg ctagtcacag cccattgctt
      601 tccatcgtt
//
LOCUS       DADGKS010000291          602 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.301, whole genome shotgun sequence.
ACCESSION   DADGKS010000291 DADGKS010000000
VERSION     DADGKS010000291.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..602
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.301"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>602
                     /locus_tag="JXV47_003265"
     CDS             <1..>602
                     /locus_tag="JXV47_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HAX1489218.1"
                     /translation="ETTDTQTAPNGVITFEKSLDEIFKEIGIDNLKTDRLMYRIYLVS
                     HQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVSAKYEKPNTQTKDGS
                     GSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVPYVAGIQMHMVQADK
                     VTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKL"
BASE COUNT          218 a           96 c          118 g          170 t
ORIGIN      
        1 gaaacaaccg atacgcaaac cgctcctaat ggggtaatta cgtttgaaaa gagcctagat
       61 gaaattttta aagagatagg catagacaat ctcaagaccg atcgtttaat gtatcgaatc
      121 tacttggtaa gtcatcaaga cgatgataaa attgtaccgg gtattgatag tacgggctac
      181 tttttaacag attcagatga tttctataat agcttagatg tatctgaaaa taatcctgac
      241 cagtttaaac atggatcagt aagtgcaaaa tatgagaaac ctaatactca aacaaaagat
      301 ggttcaggat ccacaggtgc taatggagct ataatcttag atcataagtt aacgaaaaat
      361 tataatttct catattcatc ttccgcaaag ggcacgcctt ggtatgctaa ttacaaaatt
      421 gatgaacgat tagttccata tgtagcgggt atacagatgc acatggttca ggctgacaaa
      481 gtaacatatg atgtttcgtt tgaatccgga acaaaagtag ctgatttagc aatcgagcga
      541 cgggaaggtc atgaaaatta tggcataggt tcaataacta ataatgattt aactaaactt
      601 at
//
LOCUS       DADGKS010000292          602 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.302, whole genome shotgun sequence.
ACCESSION   DADGKS010000292 DADGKS010000000
VERSION     DADGKS010000292.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..602
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.302"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>602
                     /locus_tag="JXV47_003266"
     CDS             <1..>602
                     /locus_tag="JXV47_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HAX1489219.1"
                     /translation="ETTDTQTAPNGVITFEKSLDEIFKEIGIDNLKTDRLMYRIYLVS
                     HQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVSAKYEEPNTQTKDGS
                     GSTGANGAIILDHKLTKNYNFSYSASAKGTPWYANYKIDERLVPYVAGIQMHMVQADK
                     VTYDVSFESGKKVADLAIERRKDHENYGVGSITDNDLTKL"
BASE COUNT          217 a           92 c          118 g          175 t
ORIGIN      
        1 gaaacaactg atacacaaac tgctcctaat ggggtaatta cgtttgaaaa gagcttagat
       61 gaaattttta aagagatagg catagacaat ctcaagaccg atcgtttaat gtatcgaatc
      121 tacttggtaa gtcatcaaga cgatgataaa attgtaccag gtattgatag tacgggctac
      181 tttttaacag attcagatga tttctataat agcttagatg tatctgaaaa taatcctgac
      241 cagtttaaac atggatcagt aagtgcaaaa tatgaggaac ctaatactca aacaaaagat
      301 ggttcaggat ccacaggtgc taatggagct ataatcttag atcataagtt aacgaaaaat
      361 tataatttct catattcagc ttccgcaaag ggcacgcctt ggtatgctaa ttacaaaatt
      421 gatgaacgat tagttccata tgtagcgggt atacagatgc acatggttca ggctgacaaa
      481 gtaacatatg atgtttcttt tgaatcaggg aaaaaagtgg ctgatttagc aattgaacgg
      541 cgcaaagatc atgaaaatta tggtgtaggt tcaattactg ataatgatct taccaaactt
      601 at
//
LOCUS       DADGKS010000293          597 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.303, whole genome shotgun sequence.
ACCESSION   DADGKS010000293 DADGKS010000000
VERSION     DADGKS010000293.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..597
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.303"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..442
                     /locus_tag="JXV47_003267"
     CDS             <1..442
                     /locus_tag="JXV47_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489220.1"
                     /translation="EYKLTANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQYQFK
                     DKHLVVLLLTHDGDKVARLKNGKVVTAYSEKVDKKVVADRLAEWKKTNEQVKKTTASS
                     QKNESTELSPSDSGSGQTITGNEENQASIITNESSEGQYQTYGQ"
BASE COUNT          229 a          100 c          125 g          143 t
ORIGIN      
        1 ggaatataaa ttaactgcca attacgaaaa aggtgaattg gacatctatt tgccaaaagg
       61 aaaagaagaa aatcaattta tcaatatcga tgacgtactt agtgcgattt ctctcagaca
      121 atatcaattc aaagacaaac atttggtcgt tttgcttttg actcatgatg gcgacaaggt
      181 agcacgtttg aaaaatggaa aagtggttac agcttattct gaaaaagtgg acaaaaaagt
      241 ggtggccgat cgactagcgg aatggaaaaa gaccaacgaa caagtcaaga aaacaactgc
      301 ttcttctcaa aaaaacgagt cgacagaact aagcccttca gattctggca gtggacaaac
      361 gataacggga aatgaagaaa atcaagcctc aatcattacg aatgagtcat cagaaggaca
      421 atatcaaacc tatggacaat gaaaaacaga agttgtgaca gaagtggtca gcttcaagaa
      481 ataagaagaa atttacgaaa agtgcttctc aagtttttgt aaaatttcgg cttatttccg
      541 aagaagctac ttctggaaca ccgtgaatca gaggttgtga aatcagcggt ttgacct
//
LOCUS       DADGKS010000294          595 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.304, whole genome shotgun sequence.
ACCESSION   DADGKS010000294 DADGKS010000000
VERSION     DADGKS010000294.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..595
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.304"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..219
                     /locus_tag="JXV47_003268"
     CDS             <1..219
                     /locus_tag="JXV47_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAX1489221.1"
                     /translation="LELFQWKTPEEVKETQLERIKEELADVLIYSYMMADNLHLDLDE
                     IIEEKLIKNNLKYPVEKSAGVRKKYTEL"
     gene            287..>595
                     /locus_tag="JXV47_003269"
     CDS             287..>595
                     /locus_tag="JXV47_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAX1489222.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYLVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     P"
BASE COUNT          237 a           84 c          132 g          142 t
ORIGIN      
        1 ttagaacttt ttcaatggaa aacgccggaa gaagtaaaag aaacacaatt agaacgaatc
       61 aaagaagaac tggcagatgt attgatctat tcatacatga tggcagacaa ccttcacctg
      121 gatctagatg agatcattga agaaaaattg atcaaaaata atttgaaata tcctgtagaa
      181 aaaagcgcag gtgtacgaaa aaaatacaca gagttgtaga aatgtgtcat tcggctgttg
      241 gaaagagcaa aagaaaaaca gtaaaatgag tctggaggga gagaaaatga aaaaaaaagg
      301 aaaagcaaaa agatggctag tcaatatcct cttgttcctc ttgttattag taggactagc
      361 tttgattttc aatgaacaga tcaaggatta tcttgtcaga gagacaggag ataaatatgc
      421 tatagcgaat gtaacaaaag aagatctgaa aaagaataac gataaagatg tcagttttga
      481 ctttgatgcg gtagaaccaa tgacgacaga aggggtcatg aggtcgcaga tgagaggaac
      541 agatctacca gtgattgcta gtatcgcagt cccttcagtt tcaatcaatt taccg
//
LOCUS       DADGKS010000295          589 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.305, whole genome shotgun sequence.
ACCESSION   DADGKS010000295 DADGKS010000000
VERSION     DADGKS010000295.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..589
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.305"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..201
                     /locus_tag="JXV47_003270"
     CDS             <1..201
                     /locus_tag="JXV47_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAX1489223.1"
                     /translation="LSFVPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAI
                     LSKSLLVIVLVGILSLSLIRLL"
     gene            complement(290..>589)
                     /locus_tag="JXV47_003271"
     CDS             complement(290..>589)
                     /locus_tag="JXV47_003271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HAX1489224.1"
                     /translation="HVGTIVGIKEPLDIGVWKNQSISFDWEYMFAKTDYNYEIETQGE
                     ALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHMLGKVVVSGPFNG"
BASE COUNT          149 a          133 c           97 g          210 t
ORIGIN      
        1 ttaagttttg tcccgatcgt cattatgtct gctttatggt tcagcagtct atttacccaa
       61 aatatcggac atctgccgca gatcaatctc gaaaatgctt tggcttcagt tcctacactt
      121 ttagctgcta ttctttcaaa aagcttattg gtgatcgtct tggtaggaat tctttccctt
      181 tcgttgattc gcttattata aataaaaaaa caagagctta tggcaaatta ctgtcatgcg
      241 ctcttgtttt tatcaaagtc aaataagaaa aaaatcggcg tattcttgct tatccgttga
      301 acggaccact aacaacgact tttcctaaca tatgtcctgt ttctacgtct ttggttgctt
      361 gtttcaagtt cttcgcattc atcccatctg aatagacctt gctcaatgta ctgcggataa
      421 tcccttcatt tgctaaagca gcaatgtgcg ctaaagcttc tccttgcgtt tcgatttcat
      481 agttatagtc tgttttagcg aacatatact cccagtcgaa gctgatagat tggtttttcc
      541 aaacacctat atctaacggc tctttgatcc ctacgatcgt tcccacatg
//
LOCUS       DADGKS010000296          576 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.306, whole genome shotgun sequence.
ACCESSION   DADGKS010000296 DADGKS010000000
VERSION     DADGKS010000296.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..576
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.306"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            80..>576
                     /locus_tag="JXV47_003272"
     CDS             80..>576
                     /locus_tag="JXV47_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HAX1489225.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDAT"
BASE COUNT          217 a          106 c           93 g          160 t
ORIGIN      
        1 aaaaatccat acaaaaaagg aagtcccttc tgtagaataa agttaacgac aaccaattca
       61 cagaaaagag gacttcccta tgaatgattt tactacagaa attgtgcaaa ctctagtcac
      121 taaaggcgat ttaaatgaat tattccgttc gcacttagaa aaagcgataa acacactcct
      181 acggactgaa ttaacggctt ttttagatta cgaaaaatat gatcgcactg gttttaattc
      241 aggtaattcg agaaacggtt cttactttcg atcaatcaaa accgaatatg gtgaattaac
      301 attggaaata cctagagatc gtaatggtga gtttaaacaa caaactttac cagcctacaa
      361 aagaacaaac gatacattgg aaaccactat tatccattta ttcgaaaaag gtgttacgat
      421 gtctgaaatt gctgatttga tcgaaaaaat gtacggtcat cactatactc cacaaaccat
      481 gtccaacatg actaaagttc tgactgaaga agtaaatgcc tttaaatcca gagccttaaa
      541 tgataagtat gtcgctattt ttatggacgc tactta
//
LOCUS       DADGKS010000297          575 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.307, whole genome shotgun sequence.
ACCESSION   DADGKS010000297 DADGKS010000000
VERSION     DADGKS010000297.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..575
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.307"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            312..>575
                     /locus_tag="JXV47_003273"
     CDS             312..>575
                     /locus_tag="JXV47_003273"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HAX1489226.1"
                     /translation="MSAVVTDLTYVRVGTNWAYICLMIDLFNREIIGHSCGNKKDAQL
                     VKRAIQSIPYSLQEIELFHTDRGKEFDNQTIQNLMNGLVIKFLS"
BASE COUNT          195 a          105 c           82 g          193 t
ORIGIN      
        1 ttttacactc tctattattc ttttcataaa tattgtaaat agaagtatta aaaatatata
       61 caaaaagtat tatttcgaga aagataaata ttttcaaaaa ccttttcata atcctcaccc
      121 tttcttacac tgataaatca tgcgtctaat attcaaatta tactcgatat gctttagcta
      181 atcagccaac tctgtttgtc tactatcatt atatcaatag acaatatctg ctcccgtctt
      241 tatgatcgtg ccaaagcaat caaaagaaaa ttgcgaatca cttagatcga aagtttactc
      301 aaacaaaagc attgtcagcg gttgtcacgg atttaactta tgttcgggtc gggacaaatt
      361 gggcttatat ttgtttgatg attgatttat tcaatcgtga aattattggc cattcttgcg
      421 gaaataaaaa agatgcgcag cttgtaaaaa gggccattca aagcattcct tactcacttc
      481 aagaaatcga actcttccat acggatcgtg gaaaagaatt tgataaccaa accattcaga
      541 atctcatgaa tggtttggtt atcaaattcc tttcc
//
LOCUS       DADGKS010000298          571 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.308, whole genome shotgun sequence.
ACCESSION   DADGKS010000298 DADGKS010000000
VERSION     DADGKS010000298.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..571
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.308"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT          186 a           81 c           81 g          223 t
ORIGIN      
        1 tcttgatgtg atatccttgt cttttttgta atgtttttaa cttattgctt ttgcaaaatt
       61 tatttacctg ttttctggat caacgatagt gtacattatg ctatccttgt ttggatttta
      121 ggacgtttaa agaggcactt ttttacataa cttaatccat agacctttta agcatgctgt
      181 gagataataa taaagaagag tttaaagcgc accccaaacc acttccccat aagtgtatta
      241 cgctttaaac tcttttatat ttgaattcac taagaagcat accatatttt tgaaaaaaag
      301 tgagaaaaaa ggcttataat taggatttag agtaattaat tagatgttta ttttatagga
      361 ctgatactat agattacaaa tagtatcgta tttcgcaatc ttaaaattat cttcttactg
      421 tgaataagat aataaaattt gtatttgtcc tttttaggta acttatttta atctatatac
      481 ctttctggat caacgaaagt atactttata tagtcataac gccgatggta actatgcact
      541 gtaacgataa tgctgctaaa atatcttttt a
//
LOCUS       DADGKS010000299          569 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.309, whole genome shotgun sequence.
ACCESSION   DADGKS010000299 DADGKS010000000
VERSION     DADGKS010000299.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.309"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>569
                     /locus_tag="JXV47_003274"
     rRNA            <1..>569
                     /locus_tag="JXV47_003274"
                     /product="16S ribosomal RNA"
BASE COUNT          139 a          131 c          173 g          126 t
ORIGIN      
        1 gagagtggaa ttccatgtgt agcggtgaaa tgcgtagata tatggaggaa caccagtggc
       61 gaaggcggct ctctggtctg taactgacgc tgaggctcga aagcgtgggg agcaaacagg
      121 attagatacc ctggtagtcc acgccgtaaa cgatgagtgc taagtgttgg agggtttccg
      181 cccttcagtg ctgcagctaa cgcattaagc actccgcctg gggagtacga ccgcaaggtt
      241 gaaactcaaa ggaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgaa
      301 gcaacgcgaa gaaccttacc aggtcttgac atcctttgac cactctagag atagagcttc
      361 cccttcgggg gcaaagtgac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt
      421 tgggttaagt cccgcaacga gcgcaaccct tattgttagt tgccatcatt cagttgggca
      481 ctctagcaag actgccggtg acaaaccgga ggaaggtggg gatgacgtca aatcatcatg
      541 ccccttatga cctgggctac acacgtgct
//
LOCUS       DADGKS010000300          563 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.310, whole genome shotgun sequence.
ACCESSION   DADGKS010000300 DADGKS010000000
VERSION     DADGKS010000300.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..563
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.310"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..405
                     /locus_tag="JXV47_003275"
     CDS             <1..405
                     /locus_tag="JXV47_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HAX1489227.1"
                     /translation="IRLKNDRAYHAIQDLLKGRSIESTTFSIINRYLRFADKVEGKRR
                     TNWPLNEQWGRFIGRNQKEIQLTSEPKPYTIERTLNWLGRQVAPTWKMAKELDRLNQT
                     TYIQDMVNNTRLSDRHKKILEQQSMAIENLII"
     gene            420..539
                     /locus_tag="JXV47_003276"
     CDS             420..539
                     /locus_tag="JXV47_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HAX1489228.1"
                     /translation="MEIVKDILLVFGGSMLGVTVMCLMHASAAADRAMEKKGK"
BASE COUNT          186 a           88 c          144 g          145 t
ORIGIN      
        1 atccgactga aaaatgatcg agcttatcat gcaattcaag atttgttaaa aggtcgcagt
       61 attgaaagta ccacattttc cattattaac cggtacttgc gatttgcgga taaggtggaa
      121 ggcaaaaggc gaactaactg gcccttgaat gaacaatggg ggcgcttcat tggacggaat
      181 cagaaggaaa ttcaattaac ttctgaaccg aagccttata ccattgaacg aacgttgaac
      241 tggcttggac gacaagtcgc ccctacgtgg aagatggcca aggagttgga tcggttgaat
      301 cagacaacgt acattcagga tatggtaaat aatactcgac tatcagaccg gcacaaaaag
      361 attttggagc aacaaagtat ggcaattgaa aatttgatta tatgaaaaga ggaatcgtga
      421 tggaaattgt gaaagatatt ttattggtgt ttggtggcag tatgcttggt gttactgtga
      481 tgtgcttgat gcatgcaagt gcagcggcgg accgagcaat ggaaaagaaa ggaaagtgat
      541 gaaatgaatt tcggtcaaaa ttt
//
LOCUS       DADGKS010000301          547 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.311, whole genome shotgun sequence.
ACCESSION   DADGKS010000301 DADGKS010000000
VERSION     DADGKS010000301.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..547
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.311"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..236
                     /locus_tag="JXV47_003277"
     CDS             <1..236
                     /locus_tag="JXV47_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489229.1"
                     /translation="VGKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMA
                     TASYIYQLMMFKQARDAYQKEFEKANKEKKLQK"
     gene            239..421
                     /locus_tag="JXV47_003278"
     CDS             239..421
                     /locus_tag="JXV47_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489230.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
BASE COUNT          205 a           79 c          110 g          153 t
ORIGIN      
        1 ctgtgggaaa aggatccatg gatatttctg ttattcaagg tgcaaaggct gtgtatattg
       61 cttaccgcca agcgaacatg actgattata tttcattcga tgaatttatc gataaatggg
      121 attttgatat ggctactgcc agctatattt atcaattgat gatgttcaaa caagcacgcg
      181 atgcttatca aaaagaattt gaaaaagcaa ataaggaaaa aaagcttcaa aagtaaaaat
      241 tccaaagctc ttagttgaaa cgtgggtcga tgtctattcg atgttgaccg acgttttttc
      301 tatgccttca gatttggttt taagcgatat ctgtttagat gacattttgc aaatggctta
      361 caacaagagt gcttatgaag gatggaaaaa ctatgcaata aaccaatccc agaaaaacta
      421 aagaaaggag gtaaaaaatg gctaaaaaga gaacagaagc agaagtaact ttcatagcta
      481 acgatgacgg attgaaatct acgttaaaag aaatcagtgc tgaattaact aaaaatagag
      541 cagaatt
//
LOCUS       DADGKS010000302          545 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.312, whole genome shotgun sequence.
ACCESSION   DADGKS010000302 DADGKS010000000
VERSION     DADGKS010000302.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..545
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.312"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..378
                     /locus_tag="JXV47_003279"
     CDS             <1..378
                     /locus_tag="JXV47_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAX1489231.1"
                     /translation="DIQKMTLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVP
                     NVKDAVKVAKAFPTEIELMNVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELY
                     PDTVFQPTPAMEKRSAISILSDF"
     gene            400..>545
                     /locus_tag="JXV47_003280"
     CDS             400..>545
                     /locus_tag="JXV47_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1489232.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIV"
BASE COUNT          166 a           86 c          139 g          154 t
ORIGIN      
        1 gatattcaaa agatgacatt gaagatggct gcaccatcga atgtcaaagt cattattaaa
       61 acagttgatg acgcgattca tttgttaaaa gatccgcggg cgaaggacat gcgcttgatg
      121 gttttagtcc ctaatgtcaa agatgcggta aaagttgcga aagctttccc aacggaaatc
      181 gaattaatga acgtggggaa tgctgggaaa atgacaccgc catcggaaga taagaaaacc
      241 ttatcaaagg aagtgatgtt aacgacgtca gaaattcaag acttaaaaga attagttgaa
      301 ctttatccag ataccgtttt tcagcctaca ccggcgatgg aaaaacgttc agctatctct
      361 attttgagtg atttttagaa aaaaggaagg agaaaaatta tgtatgatgc atttgtagtc
      421 gctttggccg tttttattgg agttgctgga catgaaatgt tcgggatgtc catgctgagt
      481 cgtccgattg ttgttgctcc gttagcagga gcgttgatgg gggatttgca gacggggttg
      541 attgt
//
LOCUS       DADGKS010000303          540 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.313, whole genome shotgun sequence.
ACCESSION   DADGKS010000303 DADGKS010000000
VERSION     DADGKS010000303.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..540
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.313"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>540
                     /locus_tag="JXV47_003281"
     CDS             <1..>540
                     /locus_tag="JXV47_003281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HAX1489233.1"
                     /translation="LWQTPVHASEFNFAVDFELPANQIDKNKTYINVRMEPGKTQEIP
                     YTVFNRTDKSVTVETLIHSATTNSNGVIEYGESKSKFDETLSYDMKNLAKTVGEITVP
                     PQSAVTETLSLKAPEKELAGVVAGGITFQEKKENVSNKSTVGVVNQFSQVKAILIRNS
                     EKESSPNLKLKKTYADQSD"
BASE COUNT          200 a           99 c          111 g          130 t
ORIGIN      
        1 tcctttggca gacacctgtc catgcctccg aattcaattt tgcggtagat tttgaattac
       61 cggctaatca gattgataag aacaaaacat atataaatgt aaggatggag cctgggaaaa
      121 cacaggaaat cccctacacg gtctttaacc gaacagataa atcagtaaca gttgagacat
      181 tgatccactc cgctacgacg aattcaaacg gtgtgatcga atatggagaa tcaaaaagta
      241 aatttgatga aacattaagt tatgatatga aaaacttagc aaaaacagtg ggagaaataa
      301 ctgtccctcc tcaaagtgcg gtcactgaga cactttcact gaaagctcca gaaaaagagc
      361 tggctggtgt ggtcgcagga ggaatcacgt ttcaagaaaa aaaagagaac gtttctaaca
      421 aaagtacagt tggtgtcgtc aatcagtttt ctcaagtgaa agcaatcttg attcgaaata
      481 gcgaaaaaga gtcttcccca aatttgaaat taaaaaaaac ttatgcggat caaagcgatg
//
LOCUS       DADGKS010000304          534 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.314, whole genome shotgun sequence.
ACCESSION   DADGKS010000304 DADGKS010000000
VERSION     DADGKS010000304.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.314"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>534
                     /locus_tag="JXV47_003282"
     CDS             <1..>534
                     /locus_tag="JXV47_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAX1489234.1"
                     /translation="DGFKACTDPRQAAYAFERNYERPAATHPERQDYAVNWYNKFKDL
                     KPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYSGYLGGCGMGAGTKYGLTHVIGNT
                     SAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIINWARGGQVGSWFADGTYGHTGVIR
                     GLANGRMQTYEQNTELG"
BASE COUNT          163 a           80 c          137 g          154 t
ORIGIN      
        1 tgatggattt aaggcctgta ctgatccaag acaagcagca tatgcttttg aacgaaacta
       61 tgaacgtccg gcagcgacac atcctgaacg tcaagattat gcagttaact ggtataacaa
      121 atttaaagat ttaaaaccag gaggagctac tggagaagca ggactaaaac atttagagtc
      181 tttgattgga caacgaattg gcaatggtca gtgttatggc ttgtctgcag aatattcagg
      241 atatctgggt ggttgtggca tgggtgctgg aacaaaatat ggtttaactc atgtgatagg
      301 aaatacttct gcagcatctg atattggtat tgcctatgat tggtctgctg ttggttggaa
      361 agtgattcaa aaccctagat atgatcaatt agtagttggt gcaattatta attgggcaag
      421 aggtggacaa gtgggttcat ggtttgcaga tggaacttat ggacatactg gcgttatccg
      481 aggcttagct aatggtcgta tgcaaactta tgaacaaaac acagagttag gtat
//
LOCUS       DADGKS010000305          528 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.315, whole genome shotgun sequence.
ACCESSION   DADGKS010000305 DADGKS010000000
VERSION     DADGKS010000305.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.315"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(5..90)
                     /locus_tag="JXV47_003283"
     tRNA            complement(5..90)
                     /locus_tag="JXV47_003283"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(54..56),aa:Leu,seq:taa)
     gene            complement(107..178)
                     /locus_tag="JXV47_003284"
     tRNA            complement(107..178)
                     /locus_tag="JXV47_003284"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(144..146),aa:Gly,seq:gcc)
     gene            complement(190..262)
                     /locus_tag="JXV47_003285"
     tRNA            complement(190..262)
                     /locus_tag="JXV47_003285"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(227..229),aa:Thr,seq:tgt)
     gene            complement(280..361)
                     /locus_tag="JXV47_003286"
     tRNA            complement(280..361)
                     /locus_tag="JXV47_003286"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(325..327),aa:Leu,seq:tag)
     gene            complement(369..441)
                     /locus_tag="JXV47_003287"
     tRNA            complement(369..441)
                     /locus_tag="JXV47_003287"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(406..408),aa:Lys,seq:ttt)
     gene            complement(445..517)
                     /locus_tag="JXV47_003288"
     tRNA            complement(445..517)
                     /locus_tag="JXV47_003288"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(482..484),aa:Val,seq:tac)
BASE COUNT          135 a          152 c          128 g          113 t
ORIGIN      
        1 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
       61 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      121 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      181 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      241 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      301 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      361 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      421 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      481 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactt
//
LOCUS       DADGKS010000306          525 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.316, whole genome shotgun sequence.
ACCESSION   DADGKS010000306 DADGKS010000000
VERSION     DADGKS010000306.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..525
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.316"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            8..>525
                     /locus_tag="JXV47_003289"
     CDS             8..>525
                     /locus_tag="JXV47_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAX1489235.1"
                     /translation="MEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQLGTIDNH
                     DVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPIGYIRKD
                     RNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGLKNQVMV
                     KTTTEDKLVNTS"
BASE COUNT          189 a           89 c           90 g          157 t
ORIGIN      
        1 ttttatcata gaagataacc agtttcacag cgaatggatc atcagagaat tggtcaatca
       61 tcatatcgag aatatcgtgc agctcacttc tatctctcaa atcaatcagt tgatccagtt
      121 gggcactatt gataatcacg atgttttctt tatcgatatc gacttgaagc aatcactcac
      181 aggtattgat gtcgccgaac aaatacgtaa aaaaaatgca catagtaata ttgttttttt
      241 caccgcttat acgaattttg cagtagagat catcaatcgg aaaatccttc cgattggata
      301 tatcagaaaa gacaggaatt tatctgaaca aattcgtcaa gtgctagaac agatcaattg
      361 gaaagaacag caaatcgtaa atgtcgataa aatctttatt gatcaaaaag gtggaagtct
      421 cgtcctgtat cctcgggaaa ttttatatat tgaaagtatc aaaggtttga aaaaccaagt
      481 tatggtcaaa acaactacag aagataaatt agtgaatact tcttt
//
LOCUS       DADGKS010000307          523 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.317, whole genome shotgun sequence.
ACCESSION   DADGKS010000307 DADGKS010000000
VERSION     DADGKS010000307.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..523
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.317"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            65..352
                     /locus_tag="JXV47_003290"
                     /pseudo
     CDS             65..352
                     /locus_tag="JXV47_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
BASE COUNT          191 a           89 c           77 g          166 t
ORIGIN      
        1 acatagtgcc tttttatttt aatccatgtc ataatcagtc tatataagaa atggttgata
       61 taccatggaa ttagatacaa ataatcattc attatttctt ctttgttacc accttatttt
      121 agtagtgaaa cattgtaaac atctcattga tgatgtaatg ttagcttatg caaaaaacta
      181 tctttgaaag aatatcagaa tcacatcaca ttaccttagt tgagtgaaat cgtgataaag
      241 actactttca tattatgctc aaagcacaac ctaaaaccga attaacaaaa ttcagcaatg
      301 cctaagctca tgtctgataa aatgagactt tctaagggtc aaaaatttcc tttgaatacg
      361 atcattagct tagataaaag taaaaacctt agaactacgg ggatagcttg gttaataaga
      421 gatatcgctg ttaataaaga cataagcttg caagtatgct ctattcccaa gaatctccca
      481 cttcaagcac taaggatcgt taaattcagc taagtggcaa gta
//
LOCUS       DADGKS010000308          520 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.318, whole genome shotgun sequence.
ACCESSION   DADGKS010000308 DADGKS010000000
VERSION     DADGKS010000308.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..520
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.318"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(189..488)
                     /locus_tag="JXV47_003291"
     CDS             complement(189..488)
                     /locus_tag="JXV47_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489236.1"
                     /translation="MLFNETQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVLDARSDHRRYDYIKYTFVDPERYKD"
BASE COUNT          183 a           87 c           71 g          179 t
ORIGIN      
        1 aaagtgagaa aaaaggctta taattggagt ggtagttaat tagtgactta tttttgattt
       61 tatagcactg atactataaa atatagatat catcatatta cacaatctta atactaactt
      121 aaaaaatatc tcctttcata agtatggtga taaaatccgt tccgggctac ctttttaggt
      181 agcctacttt aatctttgta tctttctgga tcaacgaaag tatactttat atagtcataa
      241 cgccgatgat cgcttcgagc gtctagcaca tcagtcacga tatcaaacaa aaaatatacg
      301 tctttcttca ttctagtttt cgcagcaggg attttaaagt agttcttatt agaatagtag
      361 agattaatta ataagctatc ttcgattgct aaaaagaaaa cttctgaatc ccacacctta
      421 taaaaatctt tgacaaatct attcgaagga tcaaatttaa accataattg cgtctcatta
      481 aaaagcataa ccattactcc gatctatttt taaacttagt
//
LOCUS       DADGKS010000309          514 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.319, whole genome shotgun sequence.
ACCESSION   DADGKS010000309 DADGKS010000000
VERSION     DADGKS010000309.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.319"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(107..>514)
                     /locus_tag="JXV47_003292"
     CDS             complement(107..>514)
                     /locus_tag="JXV47_003292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_465591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HAX1489237.1"
                     /translation="GTPENHFSNQISLNVYSRGMGGLGLPGDLSSVSRFVKATFTKMN
                     AASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSCCNVDKGIYYYRTYED
                     SQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
BASE COUNT          162 a          103 c           78 g          171 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgagacacg acctaaagat cgtgtctaat
       61 tatgactgta tcagaaaata tgataccaaa cggatctatt cattaattaa ttgacatagt
      121 ttatctgttg ctcttttatg actggataac tgaccaattc atgacgatcc aagtcttctt
      181 tattcatatt tacagcagta atttgactgt cttcatacgt acgataataa taaatccctt
      241 tatcaacgtt acagcaagaa gaataaatcg tatattcgta ttttccttct ccagtatcgc
      301 atactccttt ttgttgctcg actgagccta gtatatgaaa aaattgactg atactttcag
      361 attctgaatc acctgatgca gcattcattt tagtaaatgt ggcttttaca aatcgagaaa
      421 cagaagagag atctccaggt aagcccaatc ctcccatccc acgactataa acattcaagc
      481 tgatctggtt tgaaaaatga ttttctggtg ttcc
//
LOCUS       DADGKS010000310          495 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.320, whole genome shotgun sequence.
ACCESSION   DADGKS010000310 DADGKS010000000
VERSION     DADGKS010000310.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..495
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.320"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            351..495
                     /locus_tag="JXV47_003293"
                     /pseudo
     CDS             351..495
                     /locus_tag="JXV47_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          182 a           59 c          109 g          145 t
ORIGIN      
        1 atatgagatc tgctttcaat ctagagacaa aaacatttta ggatactggg acataagtcg
       61 ttacagatta aaaacagcca aaggatatga atcgataagg aaaaaccaat ttgctgaaaa
      121 aaagaggaac gcaaagaggt gcatctctga tttggttgtt ttctagatag acttgtgttc
      181 cagttttttt attttttata tgaaaaggct tgcataaata aaaattcgat ggtatgatga
      241 ttttgaataa gaaatggatt gttactgtac ggcaggcaaa accagaattc agctaagaaa
      301 cagtaggcga attctaggtt tttttatttt tcttgagagg gcgaagcaaa atgaaaattg
      361 ataaaatttt gaataacaat gtcgtcattt cgaaaaatgg attcggggaa gaagtcgttt
      421 gtatgggaaa aggactagct tttcaaaaaa aagattgggg acgagatttc gccagaagcg
      481 gtccaaaaag aattt
//
LOCUS       DADGKS010000311          476 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.321, whole genome shotgun sequence.
ACCESSION   DADGKS010000311 DADGKS010000000
VERSION     DADGKS010000311.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.321"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            22..>476
                     /locus_tag="JXV47_003294"
     CDS             22..>476
                     /locus_tag="JXV47_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAX1489238.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFPAEEKEYIEKRSTEGWTPDVIIGRAERTFS
                     CSVSTLYRRFKTGEFNVLHLPMQGKRKPNGYKEKRGKQAFKRNISERKK"
BASE COUNT          178 a           87 c           95 g          116 t
ORIGIN      
        1 atacaaggag agtgaacata aatgacttat acccatctta caccaaacga gcttgtaatg
       61 atagaagcat attttcatca agaaactccg gttgctatcg ttgcgaagca gcttaaacgt
      121 ggacgccaaa caatttacaa tgtctataac tttctcaaat gtggtggaac agcacttgaa
      181 tactttgaac aatacaaaga aaataagcga cgttgtggga gaaccgaaat catttttcct
      241 gctgaggaaa aagaatacat tgaaaaaaga tcaactgaag gttggacccc agacgtcatt
      301 attggccgtg cagagcgaac cttctcttgt tcagtaagta ccctctatcg ccggtttaag
      361 acgggagaat tcaatgtttt acatttaccg atgcaaggaa aacgaaaacc aaatggttat
      421 aaggaaaaac gtggaaaaca ggcattcaaa agaaatattt ctgaacgtaa aaaaga
//
LOCUS       DADGKS010000312          471 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.322, whole genome shotgun sequence.
ACCESSION   DADGKS010000312 DADGKS010000000
VERSION     DADGKS010000312.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.322"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>471
                     /locus_tag="JXV47_003295"
     CDS             <1..>471
                     /locus_tag="JXV47_003295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HAX1489239.1"
                     /translation="FGHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIET
                     ALNQWFSRFPKNFFKSITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNG
                     ILRRNGLPKSMDFRKVNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYS"
BASE COUNT          156 a           90 c           78 g          147 t
ORIGIN      
        1 tttggtcacc ttgaaggtga tacgatcgtt ggcattcatc ataaaagtgc cgtcattact
       61 ttagttgaaa gattatctaa agtcattatc acgattaaac ccaacggccg taaggcatta
      121 gatattgaaa ctgcccttaa tcaatggttt tctcgcttcc ctaaaaactt ctttaaatct
      181 attacgtttg actgtggaaa agaattttct aactggaaag ccattagtaa ccaacatgat
      241 attgatatat attttgcgga ccctggaaca ccttctcaac gcccattaaa cgagaattct
      301 aacgggattc tgcgtcgtaa tggactgccg aaatcaatgg attttagaaa agtgaatcag
      361 acatttattt ccagtgtcag caatcaacgt aatcatattc caagaaaatc attgaattac
      421 agaacaccaa tcgaaatatt tttgagctat gtacaagaag cattttattc t
//
LOCUS       DADGKS010000313          468 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.323, whole genome shotgun sequence.
ACCESSION   DADGKS010000313 DADGKS010000000
VERSION     DADGKS010000313.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.323"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..209
                     /locus_tag="JXV47_003296"
     CDS             <1..209
                     /locus_tag="JXV47_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1489240.1"
                     /translation="LMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKH
                     QVYKQLVTNYENANDWRLDNEKFL"
     gene            169..>468
                     /locus_tag="JXV47_003297"
     CDS             169..>468
                     /locus_tag="JXV47_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1489241.1"
                     /translation="MQMIGGLTMKSFYKNKFALTNQGAEDLVKASISSFFVYCINMVP
                     AFIIMMLIDELVLENVKPPWLYFTVSFVTLLFMYWLLDREYENLYNSTYKESAHLR"
BASE COUNT          166 a           57 c           88 g          157 t
ORIGIN      
        1 atctgatgaa agaaaaaaca gttattatga tagctcatcg attatccagc attaaatctg
       61 tagatgaaat tcttgtcttg tcagaaggga aaatagtaga acgtggaaat cataatgaat
      121 taatggctaa acatcaagtg tataaacaat tggtcactaa ttatgagaat gcaaatgatt
      181 ggaggcttga caatgaaaag tttttataaa aacaaattcg ctttaactaa tcagggcgca
      241 gaagatttgg ttaaagcatc tatttctagc ttttttgtat actgcattaa tatggtacca
      301 gcattcatta taatgatgct gatagacgaa ttagttttag aaaatgtaaa gccgccttgg
      361 ctttatttta cagtatcgtt cgttactttg cttttcatgt attggttgtt agatagggag
      421 tatgaaaact tatataatag tacttataaa gaaagtgcgc atttaaga
//
LOCUS       DADGKS010000314          456 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.324, whole genome shotgun sequence.
ACCESSION   DADGKS010000314 DADGKS010000000
VERSION     DADGKS010000314.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.324"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>456
                     /locus_tag="JXV47_003298"
     CDS             <1..>456
                     /locus_tag="JXV47_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HAX1489242.1"
                     /translation="SRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGIMGVISKTV
                     LENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLVFPGGLGTL
                     EEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKW"
BASE COUNT          150 a           69 c          104 g          133 t
ORIGIN      
        1 gttcccgttt tggcaataaa gaaagttaca aatttattgc gcaaacgtta ggaaaatata
       61 tggcacaaga agaaatcgaa ctggtttacg gtggttcata ctccgggatt atgggagtga
      121 ttagtaaaac agtactggaa aataacggaa aagtcacagg tatctatcca aatggccttt
      181 ttgaaactga gctgcctggg aaagatgtta ctacatttat tcctacagag acaattgatg
      241 aaagaaaggt attattattt gaaaaaggag atgctgtcct cgttttccct ggaggtctag
      301 gtacattgga ggaattttcg caacttcttt cttggatagc gatcggcctg acacctgata
      361 agccaatcgg aatattgaat attggcggtt attacagcgg cttgcaacaa ttattagaaa
      421 cttttgcaaa agaggatttt atggataaaa aatggt
//
LOCUS       DADGKS010000315          449 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.325, whole genome shotgun sequence.
ACCESSION   DADGKS010000315 DADGKS010000000
VERSION     DADGKS010000315.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.325"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..403
                     /locus_tag="JXV47_003299"
     CDS             <1..403
                     /locus_tag="JXV47_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAX1489243.1"
                     /translation="QTFPGIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSG
                     KYTGQDRINKRGNPKARKIIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVAT
                     VACMNKLLKCMHAMVRAHTEYDYAYAVSVDH"
BASE COUNT          142 a          106 c           84 g          117 t
ORIGIN      
        1 ccaaacgttc cctgggattg gcgcactcac agccgcttta ttgctcggtg aattaggaga
       61 tatcacacga tttaaaaccc ataaacaatt gaatgccttt gtcggaatcg acatccgacg
      121 gtatcattca ggtaagtata ctggccaaga ccgcatcaat aagcgtggta atcccaaagc
      181 acggaaaatt attttcttca ccattcgaaa tatgattcgc cagcaacgcg cagctcctaa
      241 tcatattgtc gattattact acaaattaaa aaagcaacct atccctaaga aagataaggt
      301 tgccacagtt gcttgtatga acaagcttct gaaatgtatg cacgctatgg ttagggcaca
      361 tacagagtac gactatgcgt acgcggtctc agtggaccat taactaaacc acttacagta
      421 taccacttct ttgcccagat cgaaaattt
//
LOCUS       DADGKS010000316          447 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.326, whole genome shotgun sequence.
ACCESSION   DADGKS010000316 DADGKS010000000
VERSION     DADGKS010000316.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.326"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..186)
                     /locus_tag="JXV47_003300"
     CDS             complement(<1..186)
                     /locus_tag="JXV47_003300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAX1489244.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMS"
BASE COUNT          154 a           69 c           80 g          144 t
ORIGIN      
        1 agacattgta gtttctaaac tgctatgtcc taaacgtttc gatacgctaa gtatatttac
       61 tccttgataa agtaaaatag atgcatgcgt atgtcttagt ccatcaataa acagtcgaag
      121 agaaaatagg gaaaaattga ttactaaaga aaaacttact aggtcgacgg tgtagttgat
      181 tttcatactt caatagattc gaattaaacg atttcgattg gcttatacca gtcctatcca
      241 acgaaagata tatcgttctt aactctagcg gtataacttg aagctttacg taaagccaat
      301 gggaatgaac tggagatgac tttttattat ttttagtaat agctgatggg ttaatactta
      361 caactttcct tttcaaagta ccatataaaa aaacggtggg gttgtttagc gaaataaagg
      421 atctaagcca atagcttaga tccttta
//
LOCUS       DADGKS010000317          438 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.327, whole genome shotgun sequence.
ACCESSION   DADGKS010000317 DADGKS010000000
VERSION     DADGKS010000317.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.327"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            6..>438
                     /locus_tag="JXV47_003301"
     CDS             6..>438
                     /locus_tag="JXV47_003301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAX1489245.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQDMLDYYYFEKNLSYNYVIHLKTFTGMIFKF"
BASE COUNT          195 a           57 c           58 g          128 t
ORIGIN      
        1 aaataatgtg gttagaaaaa ataaatgaca aaaaatttaa gtacaccgaa cgttatacgg
       61 atcccttaac tgaaaaaaag agaaaagtgt ccgttacttt atctagcaat tcacgccaag
      121 cttggaatca agctaactta cttttgaatg aaaaaatcgc agaaaaaata aaacgaaatg
      181 aagaattacc actaactttt ggagaattaa aaactaaatg ggatgaaaaa tacaagccaa
      241 ctgtaaaaga aagttcctat cgaacaactc aggtttatct atcattaatt tcaaaatata
      301 taaaagatga tgtacttgta aaaaacgtta atagtaatct tatacaagat atgctagatt
      361 actactattt tgaaaaaaat ttatcatata attatgtaat acatttaaaa acttttacag
      421 gaatgatttt taaattcg
//
LOCUS       DADGKS010000318          437 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.328, whole genome shotgun sequence.
ACCESSION   DADGKS010000318 DADGKS010000000
VERSION     DADGKS010000318.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.328"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..>437)
                     /locus_tag="JXV47_003302"
     CDS             complement(<1..>437)
                     /locus_tag="JXV47_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAX1489246.1"
                     /translation="QAFQEMEENIRLSIVGLSHDLRTPLTAINGYVQLLEQVEDTEKR
                     EKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEVEEVFFSFYEQFSE
                     KNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAK"
BASE COUNT          124 a           91 c           76 g          146 t
ORIGIN      
        1 ctttgcttgt ccatctgcat aacgcaataa attctgtatg atattttgca gcactcgcag
       61 caacatgagc ggatctgcta atacagttgt atttatcgag tgttcagcga acgctacctc
      121 gatatttttc tcagaaaatt gttcataaaa agagaaaaat acttcttcca cctctttaga
      181 aaaagaaagc gtatggagat ccatttcttt ttgcttcgtc tctattcgag caagatcata
      241 aaactgatcc gtcatactga gtaatcttgc aacagattgt ttgatgatcg ttaaatactt
      301 ctcccgtttc tccgtatcct ctacctgttc cagtaattgt acataaccgt taatagcagt
      361 caaaggagtt ctgagatcat gagaaaggcc gacgatcgat agtctgatgt tttcttccat
      421 ttcttgaaat gcttgtc
//
LOCUS       DADGKS010000319          433 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.329, whole genome shotgun sequence.
ACCESSION   DADGKS010000319 DADGKS010000000
VERSION     DADGKS010000319.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.329"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..>433)
                     /locus_tag="JXV47_003303"
     CDS             complement(<1..>433)
                     /locus_tag="JXV47_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489247.1"
                     /translation="HFTYQYFSYEWVKICFNEKEAKRVFPQNSRSELSKEKQLILDEA
                     HEVLQGLSWQGTYLMTEKELTNTVCERLRNVGNNSVENALKENRGYFVKQGFTLERAS
                     KDIKRLYNVKASSSFLVYLAKGAGIDEVIKELILSGVELVPL"
BASE COUNT          127 a           87 c           57 g          162 t
ORIGIN      
        1 agaggaacta attcaactcc tgataatatc aattctttta ttacttcatc tatccctgct
       61 ccttttgcta ggtagactaa aaaactacta cttgctttca cattgtatag tctcttaata
      121 tccttagaag ctcgttcaag agtgaatcct tgtttaacaa agtagcctct gttttctttt
      181 aaagcatttt ccacgctgtt attcccaaca ttacgtagac gttcacaaac agtgttagta
      241 agttctttct ctgtcattag atatgttcct tgccacgata agccctgtaa aacttcatgt
      301 gcttcatcta aaatcaattg tttttccttg ctaagttctg atcgggaatt ttgaggaaat
      361 actcttttag cctctttttc gttaaaacat atcttaaccc attcataaga aaaatattga
      421 tatgtaaaat gaa
//
LOCUS       DADGKS010000320          433 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.330, whole genome shotgun sequence.
ACCESSION   DADGKS010000320 DADGKS010000000
VERSION     DADGKS010000320.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.330"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>433
                     /locus_tag="JXV47_003304"
     CDS             <1..>433
                     /locus_tag="JXV47_003304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489248.1"
                     /translation="HFTYQYFSYEWVKICFNEKEAKRVFPQNSRSELSKEKQLILDEA
                     HEVLQGLSWQGTYLMTEKELINTVCERLRNVGDNSVKNALIKNRGYFVKQGFTLERAS
                     KDIKKLYNVKASSSFLIYLAKGAGIDETIKELILSGAGIVPL"
BASE COUNT          162 a           57 c           88 g          126 t
ORIGIN      
        1 ttcattttac atatcaatat ttttcttatg aatgggttaa gatatgtttt aacgaaaaag
       61 aggctaaaag agtatttcct caaaattccc gatcagaact cagcaaggaa aaacaattga
      121 ttttagatga agcacatgaa gttttacagg gcttatcgtg gcaagggaca tatctaatga
      181 cagagaaaga acttattaac actgtttgtg aacgcctacg taatgttggg gataacagcg
      241 tgaaaaatgc tttaataaaa aacagaggct actttgttaa acaaggattc actcttgaac
      301 gagcttctaa ggatattaag aaactataca atgtgaaagc aagtagtagt tttttaatat
      361 atttagcgaa aggggcaggg atagatgaaa caataaaaga attgatatta tcaggagctg
      421 ggatagttcc tct
//
LOCUS       DADGKS010000321          429 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.331, whole genome shotgun sequence.
ACCESSION   DADGKS010000321 DADGKS010000000
VERSION     DADGKS010000321.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.331"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            1..429
                     /locus_tag="JXV47_003305"
                     /pseudo
     CDS             1..429
                     /locus_tag="JXV47_003305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          155 a           82 c           94 g           98 t
ORIGIN      
        1 gaattgatcg cactaagaaa gaaaaataag caactcgaaa tggagaatga tattttaaag
       61 caagcggcgc tgatattcgg acgaaaagac aagtaattga tgccaacaag cataaatatt
      121 ccatatcagc gatgtgcaaa attctaaata tttctcgtca gacctactat tatcaagcga
      181 aaccgatcga aaatgagtcc gacttagaag agatcgttca ggaagagttt attcgaaacc
      241 gaaaggctta cggtacccga aaattgaaga agtgtttagc aaagcgtggg cttcaactca
      301 gtcggcgccg aatcggtcga atcatgaaac gccgcggatt gacatctacc tatacgatcg
      361 ctcattttaa agggcaacga acagcttgta atgaagcgaa aacagcgaat gtattagatc
      421 ggaccttta
//
LOCUS       DADGKS010000322          427 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.332, whole genome shotgun sequence.
ACCESSION   DADGKS010000322 DADGKS010000000
VERSION     DADGKS010000322.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.332"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT          139 a           81 c          104 g          103 t
ORIGIN      
        1 aacctgatat ccgccaatac ttgtttgaga taaaagcaga gttggaaatt gagggtatta
       61 ccgcggagta acggccaaat aaaccactga taggcactga ccgcggggga tttgcgaagc
      121 agaaatcctc cgtggtgctg tgcctgttta tggacggcgt tagccggcca tgatgtctca
      181 ccccccgtat ctaacagggg ggtacaaaaa cacaaaaaat aagcaagcaa cgataaggaa
      241 tggctgtcct atcaaggata ataagcaatt tgtgtagatg ttaactgatt tgaaaaagtt
      301 aacaccttaa atttggaggt gagaacttgg cacaaaggaa tttagattat cggctattaa
      361 aagaccggcg taatgaatat ggcgtttcac aaaataaatt agctacgact tgtggactta
      421 gtcgccc
//
LOCUS       DADGKS010000323          427 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.333, whole genome shotgun sequence.
ACCESSION   DADGKS010000323 DADGKS010000000
VERSION     DADGKS010000323.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.333"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            76..>427
                     /locus_tag="JXV47_003306"
     CDS             76..>427
                     /locus_tag="JXV47_003306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1489249.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIF"
BASE COUNT          164 a           68 c           80 g          115 t
ORIGIN      
        1 agaaaaataa aaaggcattt atggtacact caaattgtat ttccgacgaa agaaaacaaa
       61 ggagtgtaac cataaatgac ctacaaacat cttaccatag acgaactgac aatgatagaa
      121 tcatattatc ttcaacataa taagccggtt gaaatcgcta accgaatggg acgtgctata
      181 caaactattt ataatgtagt caataagttc aagcaaggca agactgctct tgattattgg
      241 caccagtata aagaaaataa gaaaaaatgt ggtagaaaag tcattcaatt acctgctcat
      301 gaagtagatt acattaaaga gaaagtcact cttggttgga cgcctgacgt cattatcggg
      361 cgaaaagaaa ggtctgtttc atgcggtatg agaacacttt atcgtttatt ttctaaagga
      421 atatttg
//
LOCUS       DADGKS010000324          423 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.334, whole genome shotgun sequence.
ACCESSION   DADGKS010000324 DADGKS010000000
VERSION     DADGKS010000324.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.334"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..>423)
                     /locus_tag="JXV47_003307"
     rRNA            complement(<1..>423)
                     /locus_tag="JXV47_003307"
                     /product="16S ribosomal RNA"
BASE COUNT           85 a          132 c           98 g          108 t
ORIGIN      
        1 gttgagccgg gggctttcac atcagactta agaaaccgcc tgcgctcgct ttacgcccaa
       61 taaatccgga caacgcttgc cacctacgta ttaccgcggc tgctggcacg tagttagccg
      121 tggctttctg gttagatacc gtcaagggat gaacagttac tctcatcctt gttcttctct
      181 aacaacagag ttttacgatc cgaaaacctt cttcactcac gcggcgttgc tcggtcagac
      241 tttcgtccat tgccgaagat tccctactgc tgcctcccgt aggagtttgg gccgtgtctc
      301 agtcccaatg tggccgatca ccctctcagg tcggctatgc atcgtggcct tggtgagccg
      361 ttacctcacc aactagctaa tgcaccgcgg gtccatccat cagcgacacc cgaaagcgcc
      421 ttt
//
LOCUS       DADGKS010000325          421 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.335, whole genome shotgun sequence.
ACCESSION   DADGKS010000325 DADGKS010000000
VERSION     DADGKS010000325.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.335"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..390
                     /locus_tag="JXV47_003308"
     CDS             <1..390
                     /locus_tag="JXV47_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAX1489250.1"
                     /translation="KDRKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSL
                     IENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFD
                     TYNQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          163 a           74 c           65 g          119 t
ORIGIN      
        1 aaagaccgaa aagaaatctg tgatgacttt aaggctgttt atcaagctaa ctcaaaagaa
       61 gaagcgaata ccttcttatc cggcatgatt gagaaatgga agaaaaacta tcctaaagtg
      121 acgcagtcac tcatagaaaa ccaagactta ttaacttttt atgattttcc acctagcatt
      181 cgtagaacca tttactcaac caatctaatc gagtctttca ataagcaaat taaaagatac
      241 agccgtagaa aagagcagtt tcaaaatgaa gaatcactag aacgctttct agtcagcatt
      301 tttgatacat acaatcaaaa atttctaaac agaagccata aaggttttca acaggtaacc
      361 gatacattag tttcaatgtt tactgagtaa ctaattattt tgcaggagga caatttattt
      421 a
//
LOCUS       DADGKS010000326          416 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.336, whole genome shotgun sequence.
ACCESSION   DADGKS010000326 DADGKS010000000
VERSION     DADGKS010000326.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.336"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>416
                     /locus_tag="JXV47_003309"
     CDS             <1..>416
                     /locus_tag="JXV47_003309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAX1489251.1"
                     /translation="NPLTLSGSSLISNLDKKIISFTARYDINIKGFDYLCEVAKNLPV
                     GWAIRIAGDGTEEERKELKRLIEKNGVLDKIICAGALFGDELINHYIESSIFISTSRS
                     EGLPLVLIEAMTYGLPVISFDHGGAKEILQDGNYGI"
BASE COUNT          150 a           43 c           87 g          136 t
ORIGIN      
        1 aacccattga cattaagcgg ctctagttta ataagtaacc ttgataaaaa aattatttca
       61 tttactgcca gatacgatat aaatattaaa gggtttgatt atttatgtga agtagctaaa
      121 aacttacctg ttggatgggc tataaggatt gctggagatg gtacagaaga agaacgtaaa
      181 gagctgaaaa gattaattga gaaaaatggt gtgttagata aaattatttg cgcaggtgca
      241 ttatttggag atgaattaat caatcattat atagaaagtt ctattttcat atctacttct
      301 agaagtgagg gactaccatt agtgttgata gaagcaatga cttatggatt acctgtaata
      361 agttttgatc atggtggtgc taaggaaata ttacaagatg gaaattatgg aatttt
//
LOCUS       DADGKS010000327          410 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.337, whole genome shotgun sequence.
ACCESSION   DADGKS010000327 DADGKS010000000
VERSION     DADGKS010000327.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..410
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.337"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>410
                     /locus_tag="JXV47_003310"
     CDS             <1..>410
                     /locus_tag="JXV47_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAX1489252.1"
                     /translation="PFHVLASENSTYKIAKERTETTEMSNSDVTAESSELLTTLSSES
                     STTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTISSAESST
                     TSSSTSEITSSKVTRPNHIESSKKEAPKTEGQTK"
BASE COUNT          162 a           80 c           76 g           92 t
ORIGIN      
        1 acctttccat gtgttggcaa gcgaaaattc aacatacaaa attgcaaaag aaagaaccga
       61 gacgactgaa atgagtaatt ccgatgtaac agcagagagt agtgaacttt tgacaacttt
      121 atcaagtgaa agtagtacga cttcaaatgc tgagtcttca acaacttcat caagtgaaag
      181 tagtacgact tcaaatgccg agtcttcaac aacttcgtca agtgaaagta gtacgacttc
      241 aaatgccgag tcttcaacaa cttcgtcaag tgaaagtagt acgatttcaa gtgccgaatc
      301 ttcaacaact tcaagtagta caagtgaaat aacttcttcg aaagtgacaa gaccaaacca
      361 tatagagtct tcaaaaaagg aagcgccaaa aacggaagga caaacaaaaa
//
LOCUS       DADGKS010000328          387 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.338, whole genome shotgun sequence.
ACCESSION   DADGKS010000328 DADGKS010000000
VERSION     DADGKS010000328.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.338"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>387
                     /locus_tag="JXV47_003311"
     CDS             <1..>387
                     /locus_tag="JXV47_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAX1489253.1"
                     /translation="NGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIVSDIF
                     NNVKSTIANIWEGIKKTVSAPIDWIRDKISGIFDNLNISIPHIPLPEFIMEGSFNPLK
                     GQIPHLRVKWHAKGGIFTKPTLLGGM"
BASE COUNT          135 a           65 c           74 g          113 t
ORIGIN      
        1 ggaacggtat caaaaatact gctttgaatc tttggaatgg aattacaagc actattagct
       61 ctaaagtaaa cgatggaaaa aatgcaattt caagcggttg gtccaatcta acaggtattg
      121 tttccgacat attcaataat gttaaaagta caattgctaa catatgggaa ggcatcaaaa
      181 agactgttag cgctccaatt gattggatta gagacaaaat cagtggcatt tttgataatt
      241 tgaatatttc tataccacat attccgttac cggaatttat catggaaggc agctttaacc
      301 cgctaaaagg tcaaatcccc catttgcgtg taaaatggca tgctaaagga ggtatcttta
      361 ctaaaccaac tttactaggt ggaatga
//
LOCUS       DADGKS010000329          382 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.339, whole genome shotgun sequence.
ACCESSION   DADGKS010000329 DADGKS010000000
VERSION     DADGKS010000329.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.339"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(149..>382)
                     /locus_tag="JXV47_003312"
     CDS             complement(149..>382)
                     /locus_tag="JXV47_003312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489254.1"
                     /translation="SHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFMDYQKLDQLI
                     ERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
BASE COUNT          132 a           60 c           39 g          151 t
ORIGIN      
        1 aaacgaatga ttggagttat caacattttt tcactcgttt ttagcgaaac aaaaaatgac
       61 atttgtcaca gcctcattaa attattgatt ctttttcttt ataattgaat tgtccatatt
      121 taaagtgtct agtactctac atgaataatt aattgctttc actcaaatac ttataatcta
      181 ttaacttgta gttgtttaac ttttctgaaa aagttagacc cacgtaataa tcttcccagc
      241 tttctctttc aattaactga tccaattttt gataatccat aaattcatca tgtatcaaaa
      301 agaataaata acttgatatt ttagcatcta gcttaatcag attaaataat gtttgtttaa
      361 aattgctacc attaatatga ct
//
LOCUS       DADGKS010000330          380 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.340, whole genome shotgun sequence.
ACCESSION   DADGKS010000330 DADGKS010000000
VERSION     DADGKS010000330.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..380
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.340"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>380
                     /locus_tag="JXV47_003313"
     CDS             <1..>380
                     /locus_tag="JXV47_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAX1489255.1"
                     /translation="FPSRSRFTRLSSNLAYTIKIIRYFFIKKLTKGELVGIIDSFPSP
                     LCKPVRNRQAKLLNQIAKVGYNSTKKSYFYGLKIHMIVTKTGFPITYSITNPGVHDVK
                     VLETLSEEANLPNILGDKGYISHK"
BASE COUNT          133 a           71 c           62 g          114 t
ORIGIN      
        1 ctttcctagt aggagtcgat tcactcgctt aagttcaaac ttagcttaca ctatcaagat
       61 tattcgatac tttttcatca agaagctcac caaaggtgaa ctagtcggaa ttatagatag
      121 ttttcctagt ccattatgta aaccagttag aaatagacaa gcaaaactat tgaatcaaat
      181 agccaaagtt ggctataact caacaaaaaa atcttatttt tatggtctta aaattcatat
      241 gatcgttact aagactggct ttccgattac ttactcaatc acgaatccag gtgtccatga
      301 cgtgaaagtg ttagagactt tatcggaaga agcgaatctt cccaatatcc taggggacaa
      361 aggatatatt agccataaaa
//
LOCUS       DADGKS010000331          368 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.341, whole genome shotgun sequence.
ACCESSION   DADGKS010000331 DADGKS010000000
VERSION     DADGKS010000331.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.341"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..272)
                     /locus_tag="JXV47_003314"
     CDS             complement(<1..272)
                     /locus_tag="JXV47_003314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489256.1"
                     /translation="MINLGEWGMIAGSITAIVSLILLVIRPIAASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKT"
BASE COUNT          106 a           69 c           52 g          141 t
ORIGIN      
        1 aaagttttga tttgttgcgt gtgttccacc aatttttctg tatgtgtatc taatctttca
       61 tcgtgtttct ttagttcttc atgaatcatc aatcgatctg atttgctcga ttctaaatct
      121 ttagtcagca aatctaaatt gtggcttact tttgaaagag tctcagtaat tttcgagaaa
      181 gatgcagcaa tcggtctaat tactaataaa atcaaagaaa cgatagcggt tattgatcct
      241 gctatcattc cccattcccc taaattaatc atgtgacaac tcctttacct taaataaaaa
      301 cgcatcaatt aagatgcgct cttatcttta ttaatgattt tatctgcttc ttcgtctgta
      361 atgcataa
//
LOCUS       DADGKS010000332          331 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.342, whole genome shotgun sequence.
ACCESSION   DADGKS010000332 DADGKS010000000
VERSION     DADGKS010000332.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..331
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.342"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT           95 a           87 c           48 g          101 t
ORIGIN      
        1 atactaaacc ccaagttaaa cccctccttc gcgctgtcgc taataaaaag agtgtaaacc
       61 tttctgttac tctttgacaa agagtaacat tttcctaatt gtgacatggc tgtcacaatt
      121 ccaaatgctc tccgagggta ttcgctgtca caagtgacaa cgaaaaaagg agccgaaagc
      181 gtgtcacgct ctcaactcct tttacgcttt attttgcttc acgcaaaata atcgcttatc
      241 gtaaactcac gtcattaaac attgacgtaa atttactctc actcatctga cttttcttat
      301 tcggtatcac ttctctgtca cgtccaaacc c
//
LOCUS       DADGKS010000333          331 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.343, whole genome shotgun sequence.
ACCESSION   DADGKS010000333 DADGKS010000000
VERSION     DADGKS010000333.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..331
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.343"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT          127 a           54 c           45 g          105 t
ORIGIN      
        1 tctttttcgt tgctttgctc ataaaaatct gcatattcat cactaatatt ttttctaata
       61 aattcttcca tcataaagat cacctcgaaa agagtatacg aacaaacgtt ctttttgtaa
      121 aggtggaatt tattatacta aataaatagg tgaacaagta cttgtgccaa attatgtgcc
      181 aaaaaaaatc gaatttaata aaacacaaac aaaaagaaat cctattatga taacatttct
      241 tataataaca aacacaacag aagacgtgta atagttagtc aggaacgtac aaataacccc
      301 tgtatccttt gcggtacagg gggttatttt g
//
LOCUS       DADGKS010000334          321 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.344, whole genome shotgun sequence.
ACCESSION   DADGKS010000334 DADGKS010000000
VERSION     DADGKS010000334.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.344"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..>321)
                     /locus_tag="JXV47_003315"
     CDS             complement(<1..>321)
                     /locus_tag="JXV47_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAX1489257.1"
                     /translation="ITRHVWGDLMDEVEHLRLTDLNKSIYKKRKQTIERIFADAKEKH
                     GMRWTKYRGLEKVATHTMLVFAAMNLKKLATWLWKGKEPLFFCSKIRNEVDKKLFQAR
                     VTSL"
BASE COUNT           79 a           78 c           51 g          113 t
ORIGIN      
        1 tccaaactcg taactcgagc ttggaacagc tttttatcta cttcgtttcg aatttttgaa
       61 caaaaaaata aaggctcctt gcctttccat agccaggtgg ctaatttctt taaattcatt
      121 gcagcaaaca ctagcatcgt atgcgtcgcg actttttcca agcctcgata cttggtccaa
      181 cgcatcccat gcttttcttt tgcatccgca aatattcgtt caatcgtttg tttccgtttt
      241 ttgtaaattg atttattcag atctgttagg cgaagatgtt ccacttcatc catcagatct
      301 ccccaaacat gtctcgtgat g
//
LOCUS       DADGKS010000335          307 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.345, whole genome shotgun sequence.
ACCESSION   DADGKS010000335 DADGKS010000000
VERSION     DADGKS010000335.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.345"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT           97 a           55 c           63 g           92 t
ORIGIN      
        1 acctttgaaa aagaacatcc aacgcttttc agtgaacaat gatttcttgc ttgaacaccg
       61 tgaattagag gtcgtgaaaa agctgtcctg tatcaagtaa taagaacagc caaacaaaaa
      121 tagctcttca tattttgtcg ttttttgagc taataccgag ggtcagttga ttgaacaccg
      181 tttatatcag aggttgtgag cctgccgttt aactctgagt cacaaggagc aatttcaaaa
      241 aacagcttct catgtttgat gaatattttg acttgtgacc gaagagttgg taggagaaca
      301 ccgttta
//
LOCUS       DADGKS010000336          305 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.346, whole genome shotgun sequence.
ACCESSION   DADGKS010000336 DADGKS010000000
VERSION     DADGKS010000336.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..305
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.346"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..302)
                     /locus_tag="JXV47_003316"
     CDS             complement(<1..302)
                     /locus_tag="JXV47_003316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HAX1489258.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLW"
BASE COUNT           95 a           45 c           50 g          115 t
ORIGIN      
        1 ttccaaagaa attgtttgac tcttggaaag tcacgtttta tcaatcttga gctggcactt
       61 ttataggcat tgatgaattt tgtcaattct gttttaggtt gagctttgaa cataatatga
      121 acgtggtctt tatcatgatt ccactccact aaagtaatgt gatacgattc tgaaattctt
      181 tcaaaagtag ttttggcata atcagatatt tcatcatcaa tcacttgtct acgatatttc
      241 gttactaaaa caaggtggta ataaagaaga aatactgaat gattatttgt atctaattcc
      301 atgtt
//
LOCUS       DADGKS010000337          297 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.347, whole genome shotgun sequence.
ACCESSION   DADGKS010000337 DADGKS010000000
VERSION     DADGKS010000337.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.347"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT          105 a           33 c           46 g          113 t
ORIGIN      
        1 gactacctgt attagtcctc ttttttgacc agattttgac cagtctattt tacattctaa
       61 tatattcata tgagctaatt ttatgattaa atggtaagtt tttccttgtt tgttttagtt
      121 taaactagtg tgtaattcaa aaatctatat ggaaggatct gtggggtaaa tcattataca
      181 aaagtaaaat tttacttatt aacaggctgt agaaatataa aaaagaacta aaatttaact
      241 aaattatgtg ctattcttaa ggaaagccaa gtgtatgaga aagtttctga gaatata
//
LOCUS       DADGKS010000338          294 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.348, whole genome shotgun sequence.
ACCESSION   DADGKS010000338 DADGKS010000000
VERSION     DADGKS010000338.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.348"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>294
                     /locus_tag="JXV47_003317"
     CDS             <1..>294
                     /locus_tag="JXV47_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HAX1489259.1"
                     /translation="EDIFAYILEQAVKAGFVTEDNLYLDSTHIKANANKHKFTKEMTH
                     DEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKLKERKISKADPESGYYVKG"
BASE COUNT          114 a           46 c           65 g           69 t
ORIGIN      
        1 tgaggatatt tttgcctata ttttagaaca agcagttaaa gcaggttttg taacagagga
       61 taatttgtat ctggattcta cccacatcaa agctaacgcc aataaacata agtttacgaa
      121 agaaatgacc catgatgaag cgaaagccta tcaggatgaa ttagaagatg agatcaatcg
      181 tcaacgaata gaggctggaa aacgcccttt tactttggac ttagaaaagg aagtgaagct
      241 gaaagaaaga aaaataagta aagctgatcc ggaaagcggc tactacgtca aagg
//
LOCUS       DADGKS010000339          291 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.349, whole genome shotgun sequence.
ACCESSION   DADGKS010000339 DADGKS010000000
VERSION     DADGKS010000339.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..291
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.349"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(130..>291)
                     /locus_tag="JXV47_003318"
     CDS             complement(130..>291)
                     /locus_tag="JXV47_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAX1489260.1"
                     /translation="TPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
BASE COUNT           91 a           54 c           53 g           93 t
ORIGIN      
        1 agagatgatg gacggagagt aaggaagaga aaagacccaa ttgtattaaa ctagacaggt
       61 tatccatagc tcttaatctt atttcatctc aatacaccca ccgttaaagt tcggtgggtt
      121 atttattttt caatctttca atagctgatt gcgttcattt tcttgccttt ttaatagctt
      181 catatagtca attgttcgaa ctgcatcttc agtgctaaga gaacgataga gagccaaaaa
      241 ctcttcctca taatctacga caacattgtc tagaaaatgg cttacagggg t
//
LOCUS       DADGKS010000340          289 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.350, whole genome shotgun sequence.
ACCESSION   DADGKS010000340 DADGKS010000000
VERSION     DADGKS010000340.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.350"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT           98 a           42 c           47 g          102 t
ORIGIN      
        1 taaatggaat catttcaggt aatctcaaat aaaaaaatat acagtcctgt ggcactttac
       61 ctatgggact gtatattttt tactctcagc gggcttgttt tgactccgtg tctgactccg
      121 tcgtattgat tttaaatgat attcgatgac catttaacag gtcatttttg aaatttttgt
      181 ctctatatga ctcagtttga taattattga tagatcaatt tgggtctata tcgaacaagg
      241 gaataatcca ataaaaaatg atttagaata tcaaaataac aaaaaagag
//
LOCUS       DADGKS010000341          285 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.351, whole genome shotgun sequence.
ACCESSION   DADGKS010000341 DADGKS010000000
VERSION     DADGKS010000341.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..285
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.351"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT           97 a           45 c           48 g           95 t
ORIGIN      
        1 aaagaaagtc aattacttga tgaatcagga accaatttag tcagatgtag aaaatgttgt
       61 atggatctaa agaaaattct caagcagcgt ttcgtaacgg ataattggta ttatctgcct
      121 atctatgttt tacctttaga aaaataaatt ttggggaaga cacattctaa gtaaacaaag
      181 cggtaaaaat atcttttatt cccttagtta atccgcttac tacctactgt acaaagcaaa
      241 ttgttgttca aactgctgat cagaacgctg cttggatttt tcttt
//
LOCUS       DADGKS010000342          284 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.352, whole genome shotgun sequence.
ACCESSION   DADGKS010000342 DADGKS010000000
VERSION     DADGKS010000342.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.352"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>284
                     /locus_tag="JXV47_003319"
     CDS             <1..>284
                     /locus_tag="JXV47_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAX1489261.1"
                     /translation="LARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLIT
                     KFLFLTGLRYGELISLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRT"
BASE COUNT          120 a           34 c           42 g           88 t
ORIGIN      
        1 tttagcaaga aaacctaaga caaacgaaga aataaaaaaa gaaaaagatg gttatttatc
       61 aaaagaagaa gttcaaatga ttgctagtaa acaaaaaagt tcacatcaac agtcacgtta
      121 ttctttaatt actaaatttt tgtttttaac tggactacgt tatggtgaat tgatatcttt
      181 gactgaatct gattatgatg gtaataaaat tacggtttct ggtacttatg attacgagtt
      241 aaaaattaaa acaacaacta aaaatacagg ttcttataga acca
//
LOCUS       DADGKS010000343          281 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.353, whole genome shotgun sequence.
ACCESSION   DADGKS010000343 DADGKS010000000
VERSION     DADGKS010000343.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..281
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.353"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            52..>281
                     /locus_tag="JXV47_003320"
     CDS             52..>281
                     /locus_tag="JXV47_003320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HAX1489262.1"
                     /translation="MMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGE
                     LLKPDDKDGMGNTLYIGSLKSEVYFCLYEKDY"
BASE COUNT           84 a           44 c           68 g           85 t
ORIGIN      
        1 caaaagcgta gctggtatga ctttttcgaa gattgtctaa aagccggtgg cgtgatgaaa
       61 cgcttagacc tggcaatcaa tgatcgagtt ggcctgttag atattcctga tttaacgaaa
      121 aaatgtcaga aggaagaatg tatctccttg tttcgtacct tcaaaagcta tcgttccggg
      181 gaactgttga aacctgatga taaagatggt atgggcaata ctttgtatat tggcagtctt
      241 aagagtgagg tctatttctg tttgtacgaa aaagactatg a
//
LOCUS       DADGKS010000344          280 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.354, whole genome shotgun sequence.
ACCESSION   DADGKS010000344 DADGKS010000000
VERSION     DADGKS010000344.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.354"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..131
                     /locus_tag="JXV47_003321"
     CDS             <1..131
                     /locus_tag="JXV47_003321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAX1489263.1"
                     /translation="RVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNSNNI"
BASE COUNT           83 a           58 c           57 g           82 t
ORIGIN      
        1 aacgagtgat tcggattttt ccaaatatca attccatcac tcggataatt ggaacacttt
       61 tgatggaaaa agacactgag tggctggctt ctccacgaaa atatttagaa tttaattcga
      121 ataacattta gcaccatgaa cctgtgcgag tctcttcttt ctgaggagag acatcaagag
      181 tcgctgcgct actgctcctg acctctctcc tcagaaagaa aggcatggca gttaggttca
      241 caacgcaaaa cattgtgctt ttgatgaggt tgaactttta
//
LOCUS       DADGKS010000345          280 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.355, whole genome shotgun sequence.
ACCESSION   DADGKS010000345 DADGKS010000000
VERSION     DADGKS010000345.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.355"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..94
                     /locus_tag="JXV47_003322"
     CDS             <1..94
                     /locus_tag="JXV47_003322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAX1489264.1"
                     /translation="KEIGKVLGITRQGATNLKHRLYKKIQKMLV"
     gene            192..>280
                     /locus_tag="JXV47_003323"
     CDS             192..>280
                     /locus_tag="JXV47_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1489265.1"
                     /translation="MNTLKEDFILAKNGNEEAVVAILKRFSALV"
BASE COUNT          105 a           39 c           50 g           86 t
ORIGIN      
        1 taaagaaatt ggaaaggttc tgggtattac aagacagggt gcgacaaatt taaaacatcg
       61 actttacaaa aaaattcaaa aaatgctggt ttaatatctg cataataact aattttgtat
      121 gcttctttgc tcgtcctcct ccttccccaa aaaataaata gattataagt tcatgggaag
      181 aaggtaaatt tatgaatact ttaaaagaag atttcatttt agcaaagaat ggaaatgaag
      241 aagcagttgt ggccattctc aaaagattta gcgctttggt
//
LOCUS       DADGKS010000346          274 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.357, whole genome shotgun sequence.
ACCESSION   DADGKS010000346 DADGKS010000000
VERSION     DADGKS010000346.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..274
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.357"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT           99 a           51 c           55 g           69 t
ORIGIN      
        1 tactgtcaaa ggataagctt gaggaaagtc tacacggaga tagagacaac aacacagcat
       61 attcaaaaga aacagaagcg tgatgaccgt tgtcaccctt ctgtttcttt tgctatgtag
      121 ttaaacaaag tagttgacac ttccgctact tagtattagt acgaaagtat acttcatgat
      181 actaagtaga taagaagtga aaagcggaac ccacgatcgt caaaatgcta actgctttgc
      241 ttacaccaga taaagggaag agcaatatcg ctta
//
LOCUS       DADGKS010000347          266 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.358, whole genome shotgun sequence.
ACCESSION   DADGKS010000347 DADGKS010000000
VERSION     DADGKS010000347.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..266
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.358"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..>266)
                     /locus_tag="JXV47_003324"
     CDS             complement(<1..>266)
                     /locus_tag="JXV47_003324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489266.1"
                     /translation="FVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQTFVDW
                     VSNIWNGVKEVWSIIWADIVGIVQIPWTLITSLIQAGINIIVGI"
BASE COUNT           87 a           70 c           32 g           77 t
ORIGIN      
        1 aaaataccca cgataatatt aataccagct tgaatcaatg acgttattaa tgtccatggt
       61 atttgaacaa ttcctacaat gtctgcccaa ataatcgacc atacttcttt gactccgttc
      121 caaatatttg aaacccaatc aacgaatgtt tgccaagttt cttggactcc ttgccagatg
      181 ttggaagctc cttcaactaa tccgctccat agctctccaa accaatcaga aactccttgc
      241 caaatatctt gaacccaatc tacaaa
//
LOCUS       DADGKS010000348          266 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.359, whole genome shotgun sequence.
ACCESSION   DADGKS010000348 DADGKS010000000
VERSION     DADGKS010000348.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..266
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.359"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(34..>266)
                     /locus_tag="JXV47_003325"
     CDS             complement(34..>266)
                     /locus_tag="JXV47_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAX1489267.1"
                     /translation="LKNLPETLDAQLRTKLQNLLTYEEGIYNAMIYPYSNGKIEAKIP
                     HIKTLKRLSYGFKSFENMKIRIFLINQLIQVK"
BASE COUNT           78 a           39 c           47 g          102 t
ORIGIN      
        1 agaaggactg accttctgtc tcagattttt ttgttatttc acttgaatca attgattgat
       61 caaaaaaatc ctgattttca tgttctcaaa tgatttaaat ccataagata atcgtttcag
      121 tgtcttgata tggggaatct tggcctctat tttgccatta gaatacgggt aaatcatagc
      181 attgtaaata ccttcttcat acgttaaaag gttttgaagt ttcgtgcgaa gttgtgcatc
      241 aagtgtttca ggaagatttt ttaata
//
LOCUS       DADGKS010000349          261 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.360, whole genome shotgun sequence.
ACCESSION   DADGKS010000349 DADGKS010000000
VERSION     DADGKS010000349.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..261
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.360"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..>261)
                     /locus_tag="JXV47_003326"
     CDS             complement(<1..>261)
                     /locus_tag="JXV47_003326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489268.1"
                     /translation="VQHLVHHIDKDSFLSMSRKLMIQMFRKVWVSVLGKTYGLTTSGP
                     VAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQFLEH"
BASE COUNT           80 a           56 c           45 g           80 t
ORIGIN      
        1 atgctccaag aactgattac ataagtaagt cgtccgaggt agatttgcag ctaatgtacg
       61 atttatcccg gttaagtctg tcttatagct tggggaaatg acataggatc tgctaataat
      121 ttctgcaaca ggtccactcg tcgtcaatcc gtacgttttt cctaaaacgg atacccagac
      181 ctttctaaac atctgaatca tcaattttct actcattgat aaaaaagaat ccttatcaat
      241 gtgatgcacc aaatgctgta c
//
LOCUS       DADGKS010000350          261 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.denovo.361, whole genome shotgun sequence.
ACCESSION   DADGKS010000350 DADGKS010000000
VERSION     DADGKS010000350.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..261
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.denovo.361"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>261
                     /locus_tag="JXV47_003327"
     CDS             <1..>261
                     /locus_tag="JXV47_003327"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489269.1"
                     /translation="PGQAATITIGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPG
                     INATTTAVATTTANGLMSSTDKTKLDGIAAGAQKNPGNATTTT"
BASE COUNT           87 a           54 c           56 g           64 t
ORIGIN      
        1 tcctggccaa gcagcaacaa ttaccatagg aaccgtttct agtggttcaa ccgcttctgt
       61 tacgaatgta ggaacatcat ctgcagctag atttaatttt gttttaccaa agggagataa
      121 aggtgatcct ggaataaatg ccacaactac agctgtagct acaactacag caaatgggtt
      181 gatgtcgtcc acagataaaa ctaagttgga tggaattgca gctggagcac agaaaaatcc
      241 aggtaatgct acaactacga c
//
LOCUS       DADGKS010000351        14887 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.guided.066, whole genome shotgun sequence.
ACCESSION   DADGKS010000351 DADGKS010000000
VERSION     DADGKS010000351.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14887
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.guided.066"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..2324
                     /locus_tag="JXV47_003328"
     CDS             <1..2324
                     /locus_tag="JXV47_003328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HAX1489270.1"
                     /translation="QLQQEREARQEQEAVTVDVTPEAAAPAQAEEEQAPALDPAAEPL
                     VTVLWSESPQLKDGQQMPLHEADALFARLDAAYPAEAGYDKTAFRIDCIFQGEPDSYE
                     GRQDFGDRDGSLIEHIQSYHQFYAQDENWKKHVIATTGIEGWEQDKAHRDMLLGEFVP
                     YMKLHCSLAQMEQTAQGRLQSGETLTPEETAYLGALLSYVQECRPMLNQGQYQLPEPP
                     KLADFDQSLQDYKAQVQAEIAQEAAAAGMTVEEYAAAGYEAPQQDTFSIYQLRGGEET
                     RDYRFEPYERLQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNIDHPADFRGHSLS
                     VSDVVVLHQNGQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNENMIDGIINNTPP
                     EPQPEEPEQLSFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAARRAKEAMSFSDY
                     RPGSATAEYRHYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLAENMNKGYEITA
                     RVPSVLIAGPSNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGMGGISADDPQAV
                     SKLEKKLEKLEASQELMKAVNAYYRKHGTLDGCPHLTERGIENLKADMASGWHYEKKP
                     FQSWQLSNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVANRLQIFFEGKP
                     DAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEKPSALQLAARRE
                     KEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            2325..3269
                     /locus_tag="JXV47_003329"
     CDS             2325..3269
                     /locus_tag="JXV47_003329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489271.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            3273..3476
                     /locus_tag="JXV47_003330"
     CDS             3273..3476
                     /locus_tag="JXV47_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489272.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMLVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(3776..4012)
                     /locus_tag="JXV47_003331"
     CDS             complement(3776..4012)
                     /locus_tag="JXV47_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1489273.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(4195..4566)
                     /locus_tag="JXV47_003332"
     CDS             complement(4195..4566)
                     /locus_tag="JXV47_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489274.1"
                     /translation="MSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECICVQSI
                     SYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAACSKRM
                     RRRKEAERQRKRYWKPTHLEL"
     gene            complement(4563..5891)
                     /locus_tag="JXV47_003333"
     CDS             complement(4563..5891)
                     /locus_tag="JXV47_003333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAX1489275.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            complement(5852..6181)
                     /locus_tag="JXV47_003334"
     CDS             complement(5852..6181)
                     /locus_tag="JXV47_003334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HAX1489276.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            complement(6439..6810)
                     /locus_tag="JXV47_003335"
     CDS             complement(6439..6810)
                     /locus_tag="JXV47_003335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1489277.1"
                     /translation="MANIEDCPGFETFGADVKAARQAKRVSRKAMAEKINIDWRYLAN
                     IENDGAIPSLPVVIQLIKACGLPVERYFNPEIMREESELRQRVSHKLKLCPEEYLPII
                     EGAIDSAILIEKPKKNETEDV"
     gene            6955..7140
                     /locus_tag="JXV47_003336"
     CDS             6955..7140
                     /locus_tag="JXV47_003336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAX1489278.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            8083..8742
                     /locus_tag="JXV47_003337"
     CDS             8083..8742
                     /locus_tag="JXV47_003337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance response
                     regulator transcription factor VanR"
                     /protein_id="HAX1489279.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            8745..10088
                     /gene="vanS"
                     /locus_tag="JXV47_003338"
     CDS             8745..10088
                     /gene="vanS"
                     /locus_tag="JXV47_003338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HAX1489280.1"
                     /translation="MERKGIFIKVFSYTIIALLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPDFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQAQSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLTSTL"
     gene            10259..11065
                     /gene="vanY"
                     /locus_tag="JXV47_003339"
     CDS             10259..11065
                     /gene="vanY"
                     /locus_tag="JXV47_003339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-B/VanY-G family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HAX1489281.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGRR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            11083..11910
                     /gene="vanW"
                     /locus_tag="JXV47_003340"
     CDS             11083..11910
                     /gene="vanW"
                     /locus_tag="JXV47_003340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance accessory protein
                     VanW-B"
                     /protein_id="HAX1489282.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGEPFSFWWLVRHA
                     DKDTPYKDGLTVTNGKLTTMSGGGMCQMSNLLFWMFLHTPLTIIQRRGHEVKEFPEPN
                     SDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKIIGQVSADKEPQALYKITNG
                     SIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKCKICYPLPESVDIQEENQ"
     gene            11907..12878
                     /locus_tag="JXV47_003341"
     CDS             11907..12878
                     /locus_tag="JXV47_003341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HAX1489283.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVGHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            12871..13899
                     /gene="vanB"
                     /locus_tag="JXV47_003342"
     CDS             12871..13899
                     /gene="vanB"
                     /locus_tag="JXV47_003342"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HAX1489284.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKSAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGTFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            13905..14513
                     /locus_tag="JXV47_003343"
     CDS             13905..14513
                     /locus_tag="JXV47_003343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HAX1489285.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
BASE COUNT         3841 a         3570 c         3956 g         3520 t
ORIGIN      
        1 cccagcttca gcaggagcgc gaggcccggc aggaacagga ggccgtcacg gttgacgtta
       61 ccccggaggc agcggccccg gcgcaggccg aggaagaaca ggccccggcc cttgatccgg
      121 cagccgagcc gcttgtgact gtgctatgga gcgaaagccc ccagctaaag gacggccagc
      181 aaatgccgtt gcatgaggcc gacgcgctgt ttgcccgtct ggatgcagca tatccggcag
      241 aggcaggcta tgacaaaacc gcgttccgca ttgactgtat ctttcagggc gagccggaca
      301 gctacgaggg gcggcaggat tttggagata gggacggttc cctgatcgaa catatccaga
      361 gctaccacca attttacgcg caggacgaaa actggaaaaa gcatgtaatc gctacaaccg
      421 gcatagaggg ctgggagcag gacaaggccc atcgggatat gctgttaggc gagtttgtcc
      481 cctatatgaa gctgcattgc agccttgccc aaatggaaca gacggcgcag ggccgcttac
      541 agtccgggga aaccctgacg ccggaggaaa cggcctattt gggggcgctt ctctcttatg
      601 tgcaggagtg ccgccccatg ctcaatcagg gccagtatca gttgccggag ccgccgaaac
      661 tggctgactt cgaccagagc ttgcaggact acaaagcaca ggtacaggcc gagatcgcgc
      721 aggaggccgc cgcagccggt atgaccgtgg aggaatacgc ggcggctggc tatgaagcac
      781 cccaacagga caccttttcc atctaccagc ttcgaggcgg ggaggaaacc cgcgactatc
      841 ggtttgagcc atacgagcgt ttacaggccg cagggctggc cgtggacagt gccaactatg
      901 accttgttta tacggcaccg ctggataaaa gcacgtcttt ggaggatatt taccgcacat
      961 tcaacatcga ccacccggca gattttaggg gacacagcct ttccgtttcc gacgtggtgg
     1021 tgctgcacca gaatggacag gacaccgccc actatgtaga cagcttcggc tatatggaag
     1081 tgccggagtt tttgcgggaa aatcccctgc gtaccgccga actgtctacg gagcagaacg
     1141 aaaacatgat tgacggcatt atcaacaata cgccgcccga accgcagccg gaggaacccg
     1201 aacagctatc ttttgaggat gtggcagttg cttccggcca gacacaggag gaacccccgg
     1261 aggctgcgcc cccgcaaacg gctgtccgct attatcccat caatgaggga gccgcccgcc
     1321 gcgccaagga agccatgagc ttttctgact accggcccgg cagcgccacg gcggaatacc
     1381 ggcactatgt cgatcaggcc gtggaaattg cggagcgcca gaaaaagcgt gtggagccag
     1441 agtatcacga aaagatagac agcctccttg acacctacgc ccgcaagctg gccgagaaca
     1501 tgaataaggg ctatgagatt accgcccgcg tcccctctgt cctgattgcc gggccgtcca
     1561 atttcccggt acgggcgaaa gaaaagcaga acgccgccag tgaccgcaac atggaggaat
     1621 ttcagtacat tcagggcttg cttgacaaaa tccgcagcac cggcatgggt ggtatcagcg
     1681 ccgacgatcc gcaggccgtt tccaagctgg aaaagaaact ggaaaagctg gaagcgtcgc
     1741 aggagttgat gaaggccgtc aatgcctact accgcaagca tgggacgctg gacggatgcc
     1801 cccatctgac cgaaagaggc attgaaaacc tgaaagcgga tatggcgtcg ggctggcact
     1861 atgagaaaaa accgttccag tcctggcagc tctccaacaa taacgccgag atacgccggt
     1921 taaagggccg cattgaggaa ttgacccgcc aaaaggaggc ggcctatgtg ggatgggagt
     1981 ttgacggcgg cactgtggag atcaaccggg tggccaaccg cctgcaaatc ttctttgagg
     2041 ggaagccgga tgctgctgta cgcgacgagc tgaaaagcaa cggtttccgc tggtcgccca
     2101 aggccggggc atggcagcgg cagttaaacg acaccacaat ccgcgtcgct gaccgtatca
     2161 agtgcatcca gcccctttcc ggcgaaaagc ccagcgcctt acagcttgcg gcccgcaggg
     2221 agaaagaaaa gccctctatc cgggcgcagc tcaacgcggc caagaccgaa caggccaagc
     2281 agccaccggc gcgggaaaaa tcaaagggat tggaggtaga gtaaatgcag aagtttgaaa
     2341 atgtggacgt tctggccgcg ctggaacaga tcatgcggca gaacaccgcg ttttatcaaa
     2401 gtgactttgg cattgacaaa gacattatca ggcgggatgc cgccagcgat caggccgcag
     2461 acaagaccct gctctggatg tcccggccct ccgggacgta ctgtttccgg gaacgtgatg
     2521 ttttcctgaa agacacccga cagtacaaca catggaaatt ttacggggag cagacccgtg
     2581 acaagatact ggcctacgcg gtggagctga ccggcacaca gggcggcact atccggggca
     2641 atctctatga gctggactat ccgcagcatt tccggcacgt cattgaaacc gcccagccgg
     2701 tgagtgtgaa ccggctcttt tatgagcatg gcacccgtga catcccggag agccagcgtt
     2761 ttgacggaag ccctgaccgg gtattgggaa actttttgta ctatgaggcc cagccccatg
     2821 acccggctgt gctgcaggag gcgctacgga cggagcagca cagccggggg cgggccgtcc
     2881 ccggcgattt caaagtccac gtcaccgctt tgcatgacag ccggattgaa accgaggccc
     2941 ggcgtattgt ggacagcctg aaagatctgt ccgcgcctaa cagccccaat aaaacgcatt
     3001 tcatggtgga gatctccccg cactttgcgg cgattgcttc caccaaggat aatgaccggc
     3061 tctttgccat gctgccctat aaatccctgt gttttaccgg gatgaaaggc aggcatggcg
     3121 tgtatgccgt gattaaccgg gacgagcgcc gggatgtgag tattcgcagg ccccggccct
     3181 ctatccgcaa gcagctatcc gacagcaaac aggccgccag cccaaaaaag gcggcggcca
     3241 gaaccaaaaa gaatgaattg gaggtataag gaatgatgca ctttaccgtg gaggaagaaa
     3301 acctgatctg tatgtaccac aatgcagacc ggcgcagaac gataaacagg ctcaccgccg
     3361 tcatgctggt tatggatggg gatatgcggg cgcaggccca gcagaccctt tccaagctgg
     3421 aacgcatgac ggatgccgac tatgacggcc agaagttcca cttcacagac gaataacgaa
     3481 cagcagacgc cgggcgcggc ggccatgtgg tcgcttgcgt ccggcgtctt ttctttttgc
     3541 ctattcctac gcatttagaa cccggtattg tcggggatag gatgaagtat tcgcttgccc
     3601 ctgcaaacat gcgggagaag ccttgcagcg ggcggttttc aatcccttaa atgcgtaggt
     3661 tgcagctata attagacccc tgaaacagat atagccgcgc agcgggtgta tctgtttcag
     3721 gggtgtgcag gtgatagccg caaagcggcg taagagggtg cagccctctt gccgtctatc
     3781 tctgttccag cgggaagctc ggcaatgctt ccagcagttt cagggaaatg cgctgccgta
     3841 tatcttcgtc aatgactttc ttctttttgc cgtttgcctg tctgatctcc accgtggaaa
     3901 gctcgttgat gtagtcagca taatgggcca acactttttc cgtggcccac ctctcaccgg
     3961 caacggcggc tttgatcgtt tcatagtcca gcagcttttc ttgtccgtcc atcctgatac
     4021 ccccgtcaga ctgatttttt ctatgatacc atattcggaa gcatggaacc agagaaaacg
     4081 gcgcttttct gctggtaaat tctacgcatt tagaacagca cttcggcggg gataggataa
     4141 aacacccaca taccccgctg accatgccgg aaaagccttg aaatataagg gcttttacag
     4201 ctctaagtgc gtaggtttcc agtatctttt ccgctggcgc tcggcctctt tgcggcggcg
     4261 catccgtttg gagcaggccg cgcagtattt ggcccggtta gacttcggcg tgaacgtggc
     4321 cccgcactca cagcagcgtt tcacttcgtc ccggtctttg gtgatctcgg catacagggc
     4381 cgcatccagc gggaggacag cggccttaaa ccagcggcac agaagcgaat aggaaatgct
     4441 ctgtacgcaa atacattctt cgccgtcgtc cagcaacagg cagttgccgt cacaatagtt
     4501 gcagcactca tgcgtcagct tccgggcctt gcgatattga gggtaattca ttcgtggaat
     4561 actcatagct cttgcgtcca ttcctttccc ggcgtcatac gcaaaatgcc gtccacattc
     4621 tgcttgatga tgccgtattc ctgcatctgc tttttcgctt cgccgtactt ctcatacagc
     4681 cgttcctttt cctcggccaa tcgcttgtac tcggctttca gggcgtacag atcggggagc
     4741 tttttcacac cctgtccctt tagggccttt gccgcagctt catacaaaat caacgtgctt
     4801 tcatgctcac gccggaattt tgccttatcc gctgcattgc ggtattccat agccacgggc
     4861 cagagctgct tgtaggtaga aatattcttt atcagcaccg ccatatccgc aagccggtgt
     4921 tccatagctt tgagggtagc ggcggcctcg tcgctggcgg cggtgatctc ggccactttg
     4981 ctttccaaat ccgggtaggt gtctatccca tgttcagtca ggaaattcaa agtctttgcg
     5041 gcctgcttca aattgtggag cttcgcccac ctctcatagc ctgccgactg ctgggcctta
     5101 atgttgtttt ccagatcaat ccgcaaagaa atccccttgc gctctttggg cgctctggtg
     5161 ataacgcggc ctttgatacg ctctttgatg gcttcctcgg tgtaggcttc ccccaatgtc
     5221 ttgcagcggg taaagcgttc ctgtccggga gcgcggaaag aaataaactt tcccggcttg
     5281 atctcatagc cttgcgcctg catgagccgc aggaaatcat caaaatcttt tgcctgcggg
     5341 atagcggcgt caatggctgc tttgagcttc gctttccagc tcgtcccttt ccgctgggcg
     5401 tcccactcgg catagctctt gcccttactc tggccgggct tcaccacgga caatccgttt
     5461 tccttgcaca gcctgtcgct ggtgcgccgg atataggcat agctctgttt gttggaaatg
     5521 tacttgcgct gatttaccat atccacggca cagaaaataa tgtgattgtg gacgtggccc
     5581 ttatcaatat gggtagtcag cacataggga tatttccctt gcagcacttc ctcggcaagc
     5641 tgcttcccga tctcatgggc ctgttccggc gtggcttcgc cgggggcaaa ggattgtatc
     5701 aggtggtggc ccagattatt gcccttttgg tatgcctgcg ccagcagcat ttcaaattca
     5761 atgtccgctg tttcataaga gcaggcaaag gaggccacca gcagcttgcc gtcagttttg
     5821 tccgggttct cgatgtagtc aagggctttt ttcagcgttg acttgatagg atgtatcttt
     5881 gtaactgcca tatctgcgcc agcgccccct ttatatcctc gatgtcctgt gcgtacaccg
     5941 gccccatacc gttcagcctc tttgcaatct gattgacgtt gacgccgatc ttctgtatct
     6001 cggcggtctg cgcccggatg tcgctggtgt ccatgttgac gatatagccg tcaatgagca
     6061 tcttccgggc gtaggctgaa aagttcttcg tatgcagcag cgccattttc tgttcaatca
     6121 tagcccgttc ctccggcgtc acagggacgc gcagcacgat ttttcgcttt ctgtttgcca
     6181 tgcttcaccg tcctttccat tcaggggttt ggggatttcc ccaacaagca aaacggacgc
     6241 ggcccggcag ggacggggca ggccgttttt ccgggagtgg ctacactccc tatgcttgct
     6301 acgttactgt ttctccacta acaagacgtt tccaaagccc caaactaccc gcaaaatagc
     6361 cctctggaaa gaaaaaagtg caaaaaaata gaagctacgc tgtgcagctc ccgctaaaag
     6421 taaaacagag gatgccagtt acacatcctc cgtttcattc ttcttcggct tttcaattag
     6481 tatggcgctg tcaatcgcgc cctcgatgat cggcaggtat tcttcggggc agagtttcag
     6541 cttgtggctg accctttgcc gcagttcgct ttcctcccgc atgatctccg ggttaaagta
     6601 gcgttccaca ggaagcccgc aggctttaat aagctgtatg acaaccggca gactgggaat
     6661 ggccccgtcg ttttcgatgt tggcaagata gcgccagtca atatttattt tctctgccat
     6721 tgctttgcgc gaaacgcgct ttgcttgccg ggccgctttc acatccgcgc cgaaagtttc
     6781 aaagccggga caatcttcaa tattcgccat atcgcacctc ccacttacat tgtatatttc
     6841 atactctgcc cgtggaatgt tggtatatgc acctttctta aagtttatat ttcacatttt
     6901 gtttctttta ttcttcgagc aaaagaatta taatgtaccc tgtggaggtg tactatggac
     6961 tacatgacgt tgaaagaggc aggcgagaaa tggggtgtgc ccccacgatg gataaactac
     7021 tattgtgctg cgggacgcat ccccggcgct gtaaagatgg cgacgatctg gctcattccc
     7081 aaaactgcgg aaaagccgat tgacaggcgt acaaagaaag gaaaggcggt tactgaatag
     7141 tataatgaaa ccggcgcatt ttggatatgg ttttgaagag agagaaagca tggtattttg
     7201 tcacggaaaa actataagat gatagatggc aggctgctcc agaccgataa aaagtattct
     7261 catctgaaac agaaagaaaa gatttacaca tggatgtatg aagaagcgaa actttatcat
     7321 gacagaaatg gaaaatgccc gaaacaaaga cgaggaagct gctgctgtat cagccgtata
     7381 tggtagaatt gaaaaggccg gcatctggat tctttatggt gaagtctcca gacattggat
     7441 aactgctggt ctaatgcgcc tttgagtatg gggtgattga ttttaatacc ggggaggtac
     7501 ggctttttga ggaaaatatt ctgggattta catttggcga ttattacatt tcctgtaact
     7561 gcaaggacac ggatgatgaa gatatgagga atatagactt gctgattttc tactgtcttg
     7621 aacggtatta ggactgaatc tgctgcgcgg agtgcggcaa gagcgaccgg agggagtaca
     7681 cacaggccct gcctgtgtga aaagccatac cgcaaggtgc attcgcaaaa aagaggccgc
     7741 gcattttgct gaggcttggg gtgtccccaa caagcaaaac gagaacgccg caggcgggca
     7801 agtggtggat cagaatatcc gtaaaggata ttctgatcca ttgcttgcca gtattatcgg
     7861 gatgttttga caaccgctgt aatcgaaaca tcccaaacat taagaaggtg ttaattatta
     7921 ttatcttgat ttaattcgtt taaaccaata atatagatac atacaccatg aaaagaagcg
     7981 agtatcccaa tgacggatga ttaaaatccg aaaagaaatc gctttgaaac tacagggaaa
     8041 ctacagactg ttatgttatc ttcttaaaat ggagggattt ttatgtcgat acgaattcta
     8101 cttgtcgagg atgatgatca tatctgtaat acagtaaggg cgtttctggc tgaggcagga
     8161 tatcaggtgg atgcctgcac agatggaaat gaggcataca ccaagtttta cgaaaacact
     8221 tatcaactgg ttattcttga tattatgctg cccggtatga acgggcatga acttttgcgt
     8281 gaatttcgtg cgaaaaatga tactcccatt ctgatgatga cagccctgtc ggatgacgaa
     8341 aaccaaatcc gggcgtttga tgcagaggca gacgactatg taacaaagcc attcaagatg
     8401 cagattttac taaagcgggt ggaagccctg ctgcggcgca gcggtgcgct ggcaaaggaa
     8461 atccgtgtcg gcaggctgac acttctgccg gaggatttca cggtactttg tgacggtaca
     8521 gagctgcccc tgacacgaaa agaatttgaa atccttttgc tgctggtgca gaacaaaggc
     8581 agaaccttaa cgcatgaaat cattttgtca cgtatatggg gatatgactt tgagggtgat
     8641 ggcagcacag tccacactca tatcaaaaat ttgcgggcca agctgccgga aaatatcatc
     8701 aaaaccattc gcggtgtagg ataccgattg gaggaatcat aataatggaa agaaaaggga
     8761 ttttcattaa ggttttttcc tatacgatca ttgccctgct actgcttgtc ggtgtaacag
     8821 caacactgtt tgcacagcaa tttgtgtctt atttcagagt gatggaatta cagcaaacag
     8881 taaaatccta tcagccattg gtggaactga ttcagaatag cgataggctt gatattcaag
     8941 aggtggcagg gctgtttcac tacaataacc aatcctttga gttttatatt gaagataaag
     9001 agggaagcgt actctatgcc acaccaaatg ccaatacatc aaatagtttt agacccgact
     9061 ttctttatgt ggtacataga gatgataata tttcgattgt tgctcaaagc aaggcaggtg
     9121 tgggattgct ttatcaaggg ctgacaattc ggggaattgt tatgattgcg ataatggttg
     9181 tattcagcct tttatgcgcg tatatctttg cgcggcaaat gacaacgccg atcaaagcct
     9241 tagcggacag tgcgaataaa atggcaaacc tgaaagatgt accgccgccg ctggagcgaa
     9301 aggatgagct tggcgcactg gctcatgata tgcattccat gtatgtcagg ctgaaagaaa
     9361 ccatcgcaag gctggaggat gaaatcgcaa gggaacatga gttggaggaa acacagcgat
     9421 atttctttgc ggcagcttct catgagctaa aaacgcccat cgcggctaca agcgttctgt
     9481 tggagggaat gcttgaaaat atcggtgact acaaagatca ttctaagtat ctgcgcgaat
     9541 gcatcaaaat gatggatagg cagggcaaaa tcatttccga aatactggag cttgtcagcc
     9601 tgaatgatgg gagaatcgta cccatagctg aaccgttgga catagggcgc acggttgccg
     9661 agttgctgcc cgattttcaa accttggcag aggcaaacaa ccagcggttc gtcacagata
     9721 ttccagccgg gcaaattgtc ctgtccgatc cgaggctgct ccaaaaggca ctatccaatg
     9781 tcatattgaa tgcagttcag aacacgccgc agggaggcga ggtacggata tggagtgagc
     9841 ctggtgctga aaaatgccgc ctttttgttt tgaacatggg cgttcacatt gatgatactg
     9901 cgcttccaag gctgttcacc ccattctatc gcattgatca ggcgcaaagc agaaaaagtg
     9961 ggcgaagcgg tttaggactt gccatcgtac aaaaaacgct ggatgccatg agcctccagt
    10021 atgcgctgga aaacacctcg gatggcgttt tgttctggct ggatttaccg ctcacatcaa
    10081 cattgtaaat atttaaaact taaatgattt tgaccgacag gtataaccct gccggtcttt
    10141 ttttgctgct acaggaaaac tacagactgg ctacagggaa agtacagatg cgcttgccat
    10201 aataacaatc gtaccagcca caaatcgtag ttttattgca aaggaggcat tcgatcaaat
    10261 ggaaaaaagc aactatcatt ccaatgcgga tcatcacaaa cggcatatga aacaatccgt
    10321 ggaaaagcgg gcttttctat gtgcgttcat tatttcgttc acagtctgca cgctgttttt
    10381 ggggcggaga ctggcttccg tattggaggc aacacagata ccgcccatcc ctgcaactca
    10441 tacaggcagc agcactgacg tagtggagaa tttggaggaa aacgctcttg ccaccgccaa
    10501 agaacaggga gatgaacagg aatggagcct gattttagtg aacaggcaga accccatccc
    10561 cgcacagtac gatgtggagc ttgagcaact atcaaatggt gagcggatag atattcggat
    10621 ttctccctat cttcaagatt tgtttgatgc cgcaagaact gatggagttt acccgattgt
    10681 cgcatccgga taccgaacaa cagaaaaaca gcaagaaatt atggatgaaa aaattgccga
    10741 atataaggcg aaaggctaca cctctgcaca ggctaaagcg gaagcagaaa cttgggtggc
    10801 cgtgccggga acgagcgagc atcagcttgg tcttgctgtg gatatcaatg cggacggaat
    10861 tcattcaaca ggcaacgagg tttatagatg gctggatgaa aacagctatc gttttggttt
    10921 tattcgtcgc tacccaccag acaagacaga gataaccggt gtgagcaacg agccgtggca
    10981 ttaccgatat gttggcatcg aagctgccac agagatgtac aaccaagggg tttgccttga
    11041 ggaatattta aaaccagaaa aatgagaaaa ggatgttatg ttatggacag aaaaagattg
    11101 acacagcgtt tcccgttcct gcttccaatg agacgggcgc agagaaaaat gtgcttttat
    11161 gcgggaatga gatttgacgg ctgtcgctat gcgcagacga taggggaaaa atcgctttcc
    11221 catttgctct ttgaaacgga ttgcgcatta tacaaccaca ataccggatt tgacatgata
    11281 taccaggaaa acaaggtgtt caacttaaag ctggcagcaa agaccttaaa cggcttattg
    11341 ataagaccgg gggaaccctt ttctttctgg tggctggtac gccatgcgga caaagatacc
    11401 ccctataaag acggccttac ggtgaccaat ggtaaactca ccaccatgtc gggcggcggt
    11461 atgtgccaga tgagcaattt actattttgg atgttcctgc atacgccatt gacaattatc
    11521 cagcgcagag gtcacgaagt aaaggagttt ccagagccaa acagtgacga gattaaaggg
    11581 gtggatgcaa ccatttcaga gggctggatt gatttaaaag tgcgaaacga taccgactgc
    11641 acctaccaaa tatgggtgac cttagatgat gagaaaatca tcggtcaggt gtccgccgac
    11701 aaagagcccc aagcattata caaaattaca aatggcagta tccagtatgt ccgtgaaagt
    11761 ggcgggattt atgaatatgc ccaggttaaa cggatgcaag ttgccttagg taccggggaa
    11821 ataatagatt gcaagctgct ttatacaaac aaatgcaaaa tctgttatcc cctcccggaa
    11881 agtgtggata ttcaggagga gaaccaatga gaaaaagtgt gggcattact gtttttggat
    11941 gcgaacagga tgaggcaaat gctttccgcg ctttatcgcc ggattttcat attatcccta
    12001 cgctgattag cgatgcgata tcggcagaca acgcaaaatt ggccgctggc aatcaatgcg
    12061 ttagcgtagg ccataagtcc gaggtttccg aggcgacaat tcttgcgctg agaaaggtcg
    12121 gggtaaaata catttctacc cgcagcatcg gctgcgatca cattgatacg actgccgccg
    12181 agagaatggg aatctcggtt ggcacggttg cgtattcgcc ggacagcgtt gcggattatg
    12241 ctttgatgct gatgctgatg gccatacggg gtgcaaaacc caccatgcac gccgtggcgc
    12301 aacaagattt cagattggat cgtatccggg ggaaagaact gggggatatg actgtgggag
    12361 ttattggaac cggccatatc gggcaagcgg tcgtcaaaag gctgcgggga tttggatgcc
    12421 atgtgctggc ctatgataac agccgaaaaa tggatgcaga ttatgtccag cttgatgagc
    12481 ttctaaaaaa cagcgatatt gttacgctcc atgtgccgct ttgtgcggat acccgccatc
    12541 tgatcggtca gaagcaaatt ggagagatga agcaaggcgc atttttaatc aacaccgggc
    12601 gcggagcgct tgtcgatacc ggggcgctgg tggaggcgtt ggaaagcgga aagctgggtg
    12661 gtgcggcact ggatgtgttg gagggcgagg atcagtttgt ttataccgat tgctcgcaga
    12721 aagtgcttga ccatcccttt ttgtcgcagc ttttaaggat gccgaatgtg atcatcacac
    12781 cccatacggc gtactacact gagcgtgtgc tgcaggatac tacagaaaaa acaatcagga
    12841 attgtctcaa ttttgaaagg agtttacagc atgaatagaa taaaagtcgc aatcatcttc
    12901 ggcggttgct cggaggaaca tgatgtgtcg gtaaaatccg caatagaaat tgctgcgaac
    12961 attgatacgg aaaaattcga tccgcactac atcggaatta caaaaaacgg tgtatggaag
    13021 ctatgcaaga agccatgtac ggaatgggaa gccgacagtc tccccgccat actctccccg
    13081 gataggaaaa cgcatgggct gcttgtcatg aaagaaagcg aatacgaaac acggcgtatt
    13141 gatgtggctt tcccggtttt gcatggcaaa tgcggggagg atggtgcgat acaggggctg
    13201 tttgtattgt ctggtatccc ctatgtgggc tgtgatattc aaagctccgc agcttgcatg
    13261 gacaaatcac tggcctacat tcttacaaaa aatgcgggca tcgccgttcc cgaatttcaa
    13321 atgattgata aaggtgacaa gccggaggcg ggtgcgctta cctaccctgt ctttgtgaag
    13381 ccggcacggt caggttcgtc ctttggcgta accaaagtaa acggtacgga agaacttaac
    13441 gctgcgatag aagcggcagg acaatatgat ggaaaaatct taattgagca agcgatttcg
    13501 ggctgtgagg tcgggtgtgc ggtcatgggg aacgaggatg atttgattgt cggcgaagtg
    13561 gatcaaatcc ggctgagcca cggtaccttc cgcatccatc aggaaaacga gccggaaaaa
    13621 ggctcagaaa atgcgatgat tacagttccc gcagacattc cggtcgagga acgaaatcgg
    13681 gtgcaggaaa cggcaaagaa agtatatcgg gtgcttggat gcagagggct tgcccgtgtt
    13741 gatctttttt tgcaggagga tggcggcatc gttctaaatg aggtcaatac cctgcccggt
    13801 tttacatcgt acagccgcta cccacgtatg atggccgccg caggaatcac gcttcctgca
    13861 ctgattgaca gcctgattac attggcgtta aagaggtgat aagtatggaa aatggttttt
    13921 tgtttttaga tgaaatgttg catggcgtcc gttgggatgc caagtacgcc acatgggata
    13981 acttcacagg aaaaccggtg gatgggtatg aggtgaatcg catcatcggc acaaaggccg
    14041 tggcgtttgc tctgcgcgag gcacaaatcc atgcggctgc gcttggctat ggcttgcttt
    14101 tatgggatgg atatcggcca agaactgcgg tggactgctt cctgcgttgg gcagcgcaac
    14161 cggaggacaa tctcacaaaa gaaaaatttt accccaatat agagcgagcc gagttgatta
    14221 caaagggtta tgtggcctca caatccagcc atagccgtgg aagcgcaatt gatcttacgc
    14281 tctaccacct ggatacaggg gaacttgttt caatgggaag taacttcgat tttatggacg
    14341 aacggtcgca tcatacagca aaagggatag gggatgcaga ggcacaaaat cgaagatgct
    14401 tgcgtaaaat catggaaagc agcggatttc agtcttatcg ctttgaatgg tggcactata
    14461 agttgattga tgagccatac cccgatacct attttaattt tgccgtttca taatgaaagt
    14521 attggttttg tatcagattt tggatttgat aaaatctatg ctggtcatgg acaatctttt
    14581 actggaaagt ggttaaagca tcttttgtaa tacattgcaa attatagtat tcaatctgcc
    14641 cagcggcaga aaagaaaaaa accgctgttg ggcagacctt tcccacgccc attttgtatt
    14701 ttgctggcgg cggttttgag aaatcaaggc cgccgttctt ttctggcagc aaaaggtgtg
    14761 gcggcccata ggaggatgcc gctatgctgt tttgctattg ccatgctcta atccacttcc
    14821 accactcaaa aaaagccttg cccctccatg aactgaaccc caaaagttga actatttaat
    14881 ggactgt
//
LOCUS       DADGKS010000352        11042 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.guided.086, whole genome shotgun sequence.
ACCESSION   DADGKS010000352 DADGKS010000000
VERSION     DADGKS010000352.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11042
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.guided.086"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..703
                     /locus_tag="JXV47_003344"
     CDS             <1..703
                     /locus_tag="JXV47_003344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAX1489286.1"
                     /translation="RDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNG
                     YRFYSRFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDE
                     DIQEIRETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQ
                     QDSLFTKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSF
                     RFAFRAKSKKTSPIK"
     gene            863..2749
                     /locus_tag="JXV47_003345"
     CDS             863..2749
                     /locus_tag="JXV47_003345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAX1489287.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            2761..3708
                     /locus_tag="JXV47_003346"
     CDS             2761..3708
                     /locus_tag="JXV47_003346"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAX1489288.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            3728..4255
                     /locus_tag="JXV47_003347"
     CDS             3728..4255
                     /locus_tag="JXV47_003347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAX1489289.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(4318..4971)
                     /locus_tag="JXV47_003348"
     CDS             complement(4318..4971)
                     /locus_tag="JXV47_003348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAX1489290.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            5103..5945
                     /locus_tag="JXV47_003349"
     CDS             5103..5945
                     /locus_tag="JXV47_003349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAX1489291.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            6103..6999
                     /locus_tag="JXV47_003350"
     CDS             6103..6999
                     /locus_tag="JXV47_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAX1489292.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            7002..7715
                     /locus_tag="JXV47_003351"
     CDS             7002..7715
                     /locus_tag="JXV47_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HAX1489293.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            7735..8253
                     /gene="msrA"
                     /locus_tag="JXV47_003352"
     CDS             7735..8253
                     /gene="msrA"
                     /locus_tag="JXV47_003352"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAX1489294.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            8250..8477
                     /locus_tag="JXV47_003353"
     CDS             8250..8477
                     /locus_tag="JXV47_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HAX1489295.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            8629..9180
                     /gene="lepB"
                     /locus_tag="JXV47_003354"
     CDS             8629..9180
                     /gene="lepB"
                     /locus_tag="JXV47_003354"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAX1489296.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(9263..9805)
                     /locus_tag="JXV47_003355"
     CDS             complement(9263..9805)
                     /locus_tag="JXV47_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAX1489297.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(10042..10440)
                     /locus_tag="JXV47_003356"
     CDS             complement(10042..10440)
                     /locus_tag="JXV47_003356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAX1489298.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            10700..>11042
                     /gene="rbgA"
                     /locus_tag="JXV47_003357"
                     /gene_synonym="ylqF"
     CDS             10700..>11042
                     /gene="rbgA"
                     /locus_tag="JXV47_003357"
                     /gene_synonym="ylqF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735746.1"
                     /note="essential GTPase; functions in ribosome assembly;
                     binds a unique part of the 23S rRNA; interacts with
                     ribosomal protein L25(Ctc); Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HAX1489299.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAAR"
BASE COUNT         3963 a         1906 c         2169 g         3004 t
ORIGIN      
        1 acgtgatctg tacttggaag atttaaccga tgatgaaaag caagaagtac aagaaataca
       61 agcactgatt ttgtcgatcg aacgggatgg attggatgaa agttatcgtt cgggcaagct
      121 ttcttctaat ggttatcgtt tttactcccg ttttctttct cgattcgaac attctatcac
      181 aagccagatt ttgtctttta tcggcttttg gttcattgtt gtccgtaggt taatgcgaat
      241 cgttctccat ccgaaaatgt tttggcaaag aagatatgct gatcgtcaga catttattag
      301 tgatgaagat atccaagaaa tcagagagac atatcaaaaa aatactcagt tgattattga
      361 aagtttagat aacttgactg atatttatga tgaaacgatg gttcaatttt ttatccagca
      421 acgcaaactt gaaggaataa aaatgaactc ggggaatttg atttcttcgt ggatgatcca
      481 gcaagatagt ctgtttacga aaaaaatgct aagaggttat tatcttgaaa gaaaaatcat
      541 tgatgaatac gaagttgctg aaaaaatcac gacgttttct gcgaacagct atcgcaggaa
      601 tatcaatttg ttagaatctt atacgatgaa caaaccatct gataactttt ctttccgatt
      661 tgcgtttcga gcaaagtcaa aaaaaacgag tccaataaaa taaaaaggta aaaattttca
      721 agttttataa aaaacaaaac atatcagaac aggatcgaat cggtcctgtt ctttttttga
      781 gaacacaaaa agaacaaata ccaaaaaaat tttcctgaag ttcactattt ttatgataca
      841 atatccaaga taaggaggga acatgttgaa agaattaaaa gtaactgacc tcaaaaaaac
      901 ttatggtgaa aaagatttgt ttgaccagat ttcttttttg gtccacgaaa aagaccgtat
      961 cgggttgatt gggacgaacg ggacgggtaa aacaagtctc ttaaatatta ttgccggtat
     1021 cgatagcagc gacggtgatc ggcaaacagt gttttatcca actgattacc gtattggtta
     1081 tctttctcaa gcagctgaat tttccgatga attaactgtt ctccaagcag tctttcaagg
     1141 aaacagcccc ttgatccaaa ctgttcgagc atatgaggaa gcattgatcg aactagggga
     1201 aaacggagaa gaccctgatg tgcaaaaacg ttatgctaaa gcagaagaac aaatgaataa
     1261 agaagatgct tggactacag ataccaacgc aaagattatt ttgcaaaaat taggaatcag
     1321 tgaattagat aaaaaaatca gtactttatc aggtggtcag aaaaaacgag ttagtctggc
     1381 gcaagtgttg attgatgaac ccgatttact attactagac gaaccaacaa accatttaga
     1441 ttatgaagcg atcgagtggt tggaaaacta tttgaaacaa taccgtggcg cactattgat
     1501 ggttacccac gatcgttatt ttctagatag agtagcaaac cgaatcttcg aactttcatt
     1561 tggaaaatta tacgagtata aaggaaatta tgaagcttac gtcttagaaa aagcagaacg
     1621 tgatcgtgta gaagtagaac aagaagaaaa gcgcaagcgg ctttataaac aggaattagc
     1681 ttggatgagg gctggcgtac aggcacgtgg caccaagcag caagcacgga tcaaccgttt
     1741 cgaagatcta aaggagaact tgtaccaagt aaaccaagaa gatgatttag agctgaacct
     1801 agcgacacaa cgtttaggga aaaaagtact ggaaatcaaa gatggcagtt accgtataaa
     1861 tgaccaaaca ctgctagaac atttagattt attgattcaa tctcgggaaa gactaggtat
     1921 tactggtaaa aatggtgcgg gaaaatcgac attgcttaat attctagctg gcagaattcc
     1981 cctggatagc ggtacaatgt ctatcggtga aacggttcat cttgcgtatt atacacaaga
     2041 aaatgaagaa atggcaccag ataaacggat gattgcttac ttacaagaag ctgctgaaga
     2101 agcaaaaaca gcagatggca gtcaaatcgg agtagcagaa ttacttgaac gatttttatt
     2161 tccaagattt atgcatggga cactgatagg caaactttca ggcggagaaa aacgccggtt
     2221 atttttgttg aaactgctga ttcagcaacc taatgtttta ttattggatg aaccgaccaa
     2281 tgatttggac atagcaacat tgacgatttt ggaagattat tttagaagtt ttccaggtgc
     2341 tgtgatcact gtttcccatg accgttattt cttggacaag gtagcagata agttattagt
     2401 attccaagga aacggaaaac aagaacttta ttacggaaac atgtccagtt atttactgaa
     2461 gcaaaaagag acccagcagc ctgctgaaaa agcgaaacca aaaatacaga gcaaggaacc
     2521 tgctgaaaag aagaaattat cttacatgga acaaaaagaa tgggaaacga ttgaagatga
     2581 gattgcagaa cttgaagaaa aaatctcatt gctccaagaa gagatgaatc atcaaggaga
     2641 taatttcact cgattacaag aattgcaaaa cgacgtatct gaaacagaag cacaacttga
     2701 agaaaaaatg gcacggtggg aatacttgag tgaatgggta gaagattagg aggaaaaagg
     2761 atggaacaag cgtatcttga cttaggaaga aaattgttgg aagaagggca tcgtaaagaa
     2821 gacagaacag gcacaggcac attaagctta ttcggatacc aaatgcggtt tgatctgcaa
     2881 aaagggtttc ctttgttaac aacgaaacga gtaccttttg gattgatcaa aagcgaattg
     2941 ctttggtttt taaaaggaga tacgaatatc cgctatctat tacaaaataa aaaccatatt
     3001 tgggatgaat gggcatttga acgctacatc aaaagtccag actataatgg accagatatg
     3061 actgattttg gccatagatg tttgacagat cctgaattca atgaagaata taaaaagcag
     3121 agcaagcttt tttgcgagaa gatcctaacc gatgattcct ttgctgaaac atacggcgat
     3181 cttggacaca tctacggcta tcaatggcgt cactgggaaa caaaagacgg tggctttatc
     3241 gatcaaatca aacaagtgat cgaagcaatc aaaaagactc ctgattctag aagattgatc
     3301 gtttctgcat ggaatccgga agatgttcct agcatggctt tgcctccttg tcatacgatg
     3361 tttcaatttt atgttcaaga gggacggcta agctgccaat tgtatcaacg cagtggggat
     3421 gtgtttctag gcgttccgtt caacattgca agttatgcgt tgctgactca cctaattgca
     3481 catgaaacag gtttagcggt tggcgaattt gttcacacat taggagatgc tcatctttat
     3541 atcaatcata tcgaacaaat gaaagaacaa ttgagccgag aaatacgcgc atttccgact
     3601 ttagttttga atcaggaaaa gcagtcagta tttgattttg agatggaaga tatccaatta
     3661 gaaggatatg acccacatcc ggcgatcaaa gctcctatcg ctgtttagaa tcagaaagga
     3721 tgagaaaatg ttagctgcaa tttgggcaca ggatgaaaac ggattgattg gaaaagaaga
     3781 ccgtcttcct tggcgtttgc caaatgatct gaaattcttc aaacaaatga cagaagcaaa
     3841 tacactagtg atgggacgaa aaacattcga agggatgggt agccgtccgt tgccgaatcg
     3901 tcagacgatt gttttgacga gagattcttc ctataaagca gaaggcgtgc atgtcatgca
     3961 tagtgtggaa gacgtgcttg ctctggaaaa agaaacagac ggtatctttt tcatcgctgg
     4021 agggtcagct gtttatcaag aatttctgcc attttgtacg atattatacc gtacagtcat
     4081 ccatcatgta ttcgatggag atgcttattt tccacctgtt gactggtctg attggtcact
     4141 gatcaatact agtcaaggag aaatggatga aaaaaatcgt tatccgcatc aatttgaaac
     4201 gtatcagcgt aatgagaatc ctgtaaaaag cgggacaggc gaattgacga tataaaaaag
     4261 ctatggatag actagctgtt atttagagct gtcccatcca tagctttatt ttttttatta
     4321 agtaaagaat aaaacagaga agtacataaa acctgcacct aacataacaa acaaatgcca
     4381 aacaacatgc atatagcgga tagaattcaa gctataaaag aatgcgccta tcgtgtaaga
     4441 aagcccgcct gctaccatca aaataacacc agtcattcca agagagtgat aaagaggaac
     4501 agcagccacg acacagagcc accccataaa aatatagatg atcgtagata cttttgatac
     4561 tctctcccgt ttatgcaacg tcaacgcttt atatataatg ccaagaatcg caaacaacca
     4621 gattaataca aataaagtcc aacctagcca tcctcggata ctcagcaaac aaaaaggagt
     4681 ataacttcct gcaatcaaaa gaaaaatcga actatgatcg aatacttgga acaccttttt
     4741 tgcttttgta aaaatcaatg aatgaaacaa agtagacgtt aaaaataaaa gaatcatcat
     4801 cgatccatag atagcataag agacaatatg gagggaggaa tgcaagtggg caccttttac
     4861 taaaagaacc actagtcccg cgatactcaa tccagtccca attccatggg tgactgcatt
     4921 aaacacttca tttaatattt catacgttcg attaaatttc gttttttcca tgaaaacggc
     4981 tcctttacta ggtgtaatta atgaaaaatc attatttgtc tgttatacta aaaatagaaa
     5041 ttgtcttaca tgtagtttaa catgaataag gcatcttgtt aaagaaagag agagagaaaa
     5101 taatgacaaa tgtaaaaatc gtaacagatt cttcatgtac gatggaaaaa aatgtacgcg
     5161 atgctttagg cattcgtgtc atgccgctat ccatcatgat cgacggaaca gtatatcccg
     5221 atgatgacca actagacggc gaaagattta tggaaatgat ggcgaaagca aaaaatctgc
     5281 ccaaaacaag ccaaccacca attggagaat tcatctcgat gtatgatgag ctaggagaag
     5341 acggcagtga agtgatttcg atccatatga caaaaggctt gagtggaaca gtagaagcag
     5401 caagacaagc cagtaatcta acaaaaacga aagtaacggt tatcgacagt gataccactg
     5461 accaaggatt atcttttcag gtaattcgag cagctgaatt agcaaaagaa ggtaaaacag
     5521 tagagaaaat ccttgaagaa gtcaaaaaag tacaagacaa tacaaaatta tacatcggaa
     5581 tatccacact agataacttg gtaaaaggtg gaagaatcag ccgaacaact ggtttgctgt
     5641 ctagtgtttt gaacatacgc gtggtgatga atttcgccca ttctgaatta atccctgtaa
     5701 ctaaggggcg aggaaagaaa acgttcgata aatggtttaa taatttgaaa aatgaactga
     5761 aagaattgcc aaatgtgcga caaatcggta tttcacatgc ggatgcaaaa gaattggcgc
     5821 aagaattcaa agagggtttg caagaattat tcccggacat gcatatccct gtactgcata
     5881 cgaatccggt tatcgctacg catactggta aagacgcgtt tgcaatcatg tattatgtag
     5941 attagtcgaa aagaggataa gccctcagcc tgaaaggctt gcagcttatt ctctttttct
     6001 ttataaaatt aggaaaataa ttgttttctt ttttcataaa gactaccttt ttgataaaat
     6061 ttttgataac attagaacca atcgaataca agaggtgaaa aaatgaaatt aacgaaacga
     6121 catttgatcc tcgttttgtt cccattatta attgcgatca tcatctatgc aggtttagct
     6181 gcttctatac cgaaagctgg cccactaatg aaaccagtaa ctactgtgag agaagatcca
     6241 aataaaaaag aaaaacttca ctacatagct atcggagatt cgctgactga aggagtagga
     6301 gatcaaacca agcaaggagg attcgttccc cttgtcgcaa atgatctaaa agaccgttat
     6361 aatttgaccg cggttgaaac agaaaactat ggtgtaaatg gtgaacgaag tgaccagatc
     6421 ttaaagcgag taaaaacaaa agaagaaatt cgaaacaata tcaaaacagc tgattttatc
     6481 acactgactg ttggcggtaa tgatttgatg aaagttatcc aaaataattt attcgggtta
     6541 acggtcaatt cctttaaaaa gccactgaaa aactatcagg aaaatgtcac agaactattg
     6601 gaagaatttc gatccctcaa taaaaccgca cctatttaca ttttaggcat ctacaatcca
     6661 ttttatttga actttcctga gatcactgac atgcagacaa ttgttaacaa ttggaacaaa
     6721 ggaacagaaa cggtgacaaa aaaaatgccg aactgctact ttatcccaat caatgatttg
     6781 ctttatcaag gattgaatca ggaagtaggt gtcacagaag aaggaacaga tcaaacaact
     6841 agcacgacag aaaatctaaa tggcatcaaa aataatgtgc tctatgaaga agatcatttc
     6901 catccaaata atttaggtta tcaattgatg gcaaatgcag tgagagatca gctgatcgag
     6961 acacaaaacc aatggttaga gaaggaggat gatcaataaa catgaaaaca agatctgacg
     7021 tatcttcaaa caaaacaaag aaaacaaatt actggaaatt cgccttcctt atccttcttg
     7081 gggtagtact tggttcgacc gtatttttag gcagccgtat ttttgctaat cgggaaccag
     7141 aactcccaga aataccagct cttacggaaa gacaaggaga tcctgtctta acgatcaatt
     7201 caaataaaga aaaagtcaat caaatcatca gctttttcct tagtgagtat caaaaagata
     7261 gtgatattga atataaattt tatttggaaa atgaagcact actcaatggt actttcgaag
     7321 tactaggttt tcctatcgat ttctatttat attttgatcc gtatgtgatg gaaaacggaa
     7381 atgtccaact aaaagctaga agtctttcta tcggaacatt gagtttgcca atcaaagatg
     7441 tgatgaatat gatcaagaga aactataaat taccagattg gatcgaagtc aatacagatg
     7501 atctgactat catgcttagg ttggatcaat tccgaatgca aaacgggatg tatattaaag
     7561 cagataaaat cgacttagta aatgatgaca ttcggtttag tctatatttg ccaaaagata
     7621 cctctgatgc ttcaaacaac tcaaatacca acaaaactag caccagcagt actgaaagca
     7681 agacaaaaga aaataaaaaa tcatcggatg agtagtatta gagggggaat cataatggaa
     7741 cgagcaatat ttgcaggagg ctgcttctgg tgtatgatcc agcctttcga cacgcttcct
     7801 ggtatccata cagtgatgtc aggatatact ggagggcatg taccagatcc gacttatgaa
     7861 caagtaaaaa gccaaacgac tggacataca gaagcagtgg agattatcta tgatccaaca
     7921 ttgatttcat atgaacaatt agtagaactt tactggcagc aaactgatcc aactgacgct
     7981 ttcggacaat tcgaggatcg cggtgacaat tatcgcccgg tgatctttta tttgacagaa
     8041 gaacagcgga tcattgctga aaaaagtaag aaacagttag ctgaaagtgg acgtttcgaa
     8101 cagccaatcg ttacaaaaat cgaaccagcc caaccatttt atctagcaga agaagaccat
     8161 caagagtatt ataaaaagca tcctgaaaat tttaaaagaa accatgcacg ccgggctgcc
     8221 tttatcgaag aaaattggag gaacgaaggg tgaatcgaag cttttttcat tatttaatga
     8281 cactgcgagg cggtggcaca catgatgctt tatctgtttt cgctacagaa gccggtaaag
     8341 acatccaatt tcctaagcac agctctagct acgaagaaat ttctaattat ctggaactga
     8401 atgtcgacta tttgccgtcc atggatatct ttgacgaagc atgggaaaaa tatttagaaa
     8461 ataatcatga catataagag atagttttgt actttatgat caaaaaagtt ttttgtccaa
     8521 tagcctaatt gaaagaatta tttttatttc agctatctag tcgcattttt ttgatatttt
     8581 tcttataata aagaaagaat gaaaaaaaga gggatggatt gatagagatt gacaaaaaaa
     8641 caacgctata ttaatcgctt ctggcttgta ttcaaatact tacttgtttc tgtattcctt
     8701 gcgttcatgt tgcggggatt tttattcatc ccggtaccag tggaaggcaa ttcaatggaa
     8761 aacgtgttga agcaaggtga tatggttgtg atggaaaaat tttcggagat cagacgattt
     8821 gatattgttg tttttcaatt agcagatggc acgatttata tcaaacgagt aatcggtctt
     8881 ccaggagaaa atgtcagcta ccaaaatgat caattgaaga tcaatgggaa agtagttaag
     8941 gaaccttatc taactaaaaa cctgaaatca gatcatgcaa atgcatccta tacgacggac
     9001 tttacactac aagagctaac gggacaatcc aagcttccgg aagataatta ttttgtactt
     9061 ggagataatc gaagagtttc aaaagatagt cgttcgtttg gcacgatcaa taaaactgat
     9121 attctaggta aagcaagatt tgtctattat ccacttgatg aaataaaatg gatccagtga
     9181 gaaacaataa agcgtgcagt ctgttgagac tgcacgcttt attgtttaat ccaaaatcag
     9241 tttactacct tagtacgtaa aatcaaacag ctcgtttaaa cacttttcta gcctctaaag
     9301 ttttgataaa tgaataaaca accattattt gaatagggat ttggatcata ttcctgatga
     9361 atctacctag aaaaattact ttgaaatctg caccaaacaa aacagacatc agccaagaat
     9421 tgataaaaag gctgactggg atcataatca ataattgggc agcgatgacg gaaggcaggt
     9481 ttatcttttt atgatataaa aataagccat taataaatcc accaaggaaa gccgtgataa
     9541 gaaaagcagc ttgaaacgtt cctgaaccaa atatcgtgaa atttaaagtg ttcgacaaca
     9601 tttcaagcaa accagcccag atcggtccat atagataacc cataagcgcc atacttaaaa
     9661 atccgaatgt gatttgaaaa taagcaggac caatcgctat cttgtataag atgacatcaa
     9721 gggctaataa aagagcagag gtcgacaaca atcttgcatt catttcgggc aatctaaaaa
     9781 cgtcttttgc aatcaaagtg ttcaaaatat tctctccttt gtcagttaat aataaaagga
     9841 taccataaaa tcaccaatgt gtcatgacac attggtgatt tacatacact ggcatctaac
     9901 aattaaaaaa agggtgagaa gactgctttt ataaactgta aaaaagagat tgtacgaata
     9961 aaaaaaatag aggcggagaa tacttatcgt atcatccgcc tttgtttttt tgttataaaa
    10021 aacgtcagat tagttatctg cttacatctt catccatacg ggttctaatg tatttccgtc
    10081 tagatcttgg acttctaatg aaaacatttc ttcttcaggc attcccatat ctacttcgtg
    10141 gaaagtacca ccattttctt ttgcaatttg agcaaatttt tttacttcat ccgcattttc
    10201 aacactaaac gaaatcaaag caccacttgt ttttttatta tcagctattt ctttatcttt
    10261 tataaatttt ttataaaaat catgagagag aagcattatc caaaaagtgt catcccatac
    10321 cattgaacca gcttcttcag tagaaaattc ttcatttttt ttaaaaccca gcttttcata
    10381 aaaagcaacg gaacgattga catcagcaac aggaaaatta acaaaaacca tactattcat
    10441 ttgtttcgtc tcctttctgt tttgttcgtc tatcatctct tatttaggaa acgctgtcaa
    10501 aaatttagat tcatatatag aaaccaaaat aaaaatttgc atcatcaaaa aagtgaagat
    10561 gtgatagaat gaggactggt tcactttcac ttaactaata gatggaattt ctttataata
    10621 aaaaagtgaa tttatattga aaaagaaaaa aacaagtaaa gccggggaat attccggtat
    10681 gaaaggaatg gagagaacaa tgaccatcca atggtttccg ggacatatgg caaaagcccg
    10741 acgagaagtt tctgaaaaaa tgaaatatgt ggacatcgta tttgaattgg tagacgcacg
    10801 attaccttta tcttctcgta atccaatgct agatcagatc attcagcaaa aacctcgcct
    10861 tgttttattg aataaagcgg atctggcaga tccacaacag acaaagctgt ggcaagaata
    10921 ttttcgtaaa caaggccatc ttgcattagc tatcacggca caagaaagta aaggaattaa
    10981 aggtctagta cctgcggcta aagaagcatt gaaagaaaaa cgggcaagag atgctgctcg
    11041 gg
//
LOCUS       DADGKS010000353        10087 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.guided.088, whole genome shotgun sequence.
ACCESSION   DADGKS010000353 DADGKS010000000
VERSION     DADGKS010000353.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10087
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.guided.088"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            537..1139
                     /locus_tag="JXV47_003358"
     CDS             537..1139
                     /locus_tag="JXV47_003358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAX1489300.1"
                     /translation="MAKIGYARVSSKEQNLDRQLKALEGVSKVFSDKLSGQSVERPQL
                     QAMLNYIREGDIVVVTELDRLGRNNKELTELMNQIQIKGATLEVLNLPSMNGIEDENL
                     RRLINNLVIELYKYQAESERKRIKERQAQGIEIAKKKGKFKGRQPKFKENDPRLQHAF
                     DLFLNGCSDKEVEEQTGINRRTFRRYRSRYNVTVDQRKKQ"
     gene            1155..1832
                     /locus_tag="JXV47_003359"
                     /pseudo
     CDS             1155..1832
                     /locus_tag="JXV47_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            2344..2640
                     /locus_tag="JXV47_003360"
     CDS             2344..2640
                     /locus_tag="JXV47_003360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="HAX1489301.1"
                     /translation="MSKGFLEPALFNQERNVLDSEIKNLTTEKTNLVTNSASGVLRAN
                     EIKDLINYVSADNFNGDYTEELFEEFVVNIIVNSRDELTFNLKCGLSLKEKVVR"
     gene            2641..3057
                     /locus_tag="JXV47_003361"
     CDS             2641..3057
                     /locus_tag="JXV47_003361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HAX1489302.1"
                     /translation="MAYIPYGYKIQDGVVTVDEKAAGQVKVFFEKYISGLSLTVAGEQ
                     AGIEKTHSVMGRILKNVNYLGNDTYPAIIDKEIFDKAEEVRDKRAKDLGRVVELAAFT
                     SPPPKERFKMKKADNKMPVDPFERAEYLYSLIESEE"
     gene            3077..4621
                     /locus_tag="JXV47_003362"
     CDS             3077..4621
                     /locus_tag="JXV47_003362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAX1489303.1"
                     /translation="MVIPARKRVGSTAAKEKIKKLRVAAYCRVSTETEEQNSSYEVQV
                     SHYTEFIKKNNEWEFAGIFADDGISGTNTKKRDEFNRMIAECMDGNIDMVITKSISRF
                     ARNTLDCLQYIRQLKDKNISVYFEKENINTTDAKGEVLLTIMASLAQQESQSLSQNVK
                     LGLQYRYQQGKVQVNHKRFMGYTKDEDGNLTIVPEEAEIIKRIYREYLEGQSLVGIGR
                     ALEKDGILTAAGKPRWRPESVKKILQNEKYIGDALLQKTVTVDFLTKKRVKNEGHVPQ
                     YYVENSHEAIIPKELFLQAQEEIHRRSNIYTGEGKNKRIYSSKYALSAITFCGDCGDI
                     YRRVYWNIHGRKEFVWRCVTRIEQGPEVCKNRTVKEDELYGAVMTAINKLLAGGNNMI
                     KTLEENIHAVIGETTEYQISEINNSLEEKQKELIKLANKGQDYDHLADEIDELRDKRQ
                     ILLVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEGHFVIAFKS
                     GIEMEI"
     gene            4764..4988
                     /locus_tag="JXV47_003363"
     CDS             4764..4988
                     /locus_tag="JXV47_003363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1489304.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            5003..5872
                     /locus_tag="JXV47_003364"
     CDS             5003..5872
                     /locus_tag="JXV47_003364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HAX1489305.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            5853..6587
                     /locus_tag="JXV47_003365"
     CDS             5853..6587
                     /locus_tag="JXV47_003365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008766909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAX1489306.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            6620..7528
                     /locus_tag="JXV47_003366"
     CDS             6620..7528
                     /locus_tag="JXV47_003366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HAX1489307.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            7525..8067
                     /gene="sat4"
                     /locus_tag="JXV47_003367"
     CDS             7525..8067
                     /gene="sat4"
                     /locus_tag="JXV47_003367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HAX1489308.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            8160..8954
                     /locus_tag="JXV47_003368"
                     /note="aph(3')-IIIa"
     CDS             8160..8954
                     /locus_tag="JXV47_003368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HAX1489309.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            complement(9062..9250)
                     /locus_tag="JXV47_003369"
                     /pseudo
     CDS             complement(9062..9250)
                     /locus_tag="JXV47_003369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913594.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            9230..9802
                     /locus_tag="JXV47_003370"
     CDS             9230..9802
                     /locus_tag="JXV47_003370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAX1489310.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIEPISLGFYEQNWYLIGFAG"
BASE COUNT         3548 a         1572 c         2207 g         2760 t
ORIGIN      
        1 acaagaagca ttttattcta gcttaatttg acaaatcata ctatgatacg tgtttgtttt
       61 tctgtgctgt ttagtgaatg attagcagaa atatagagag taagatttta attaattatt
      121 agggggagaa ggagagagta gcccgaaaac ttttagttgg cttggactga acgaagtgag
      181 ggaaaggcta ctaaaacgtc gaggggcagt gagagcgaag cgaacacttg atcttttaag
      241 ttgctatctt tttaaggtca atagagtata cttatttgtc ctaatatggt tttagcagta
      301 taattgactt ggtgaatagg tcatttaagt tgggcataat aggaggagta aaatgaaaaa
      361 atttatttat cgagttttag aaaatgacga agtggtggct atttttaatg agcaacaata
      421 tgcgcaagat tttatcgctt acgaaaagac aatttctgat aagcaatttg aaattgaaaa
      481 agtagatata gctgattggt tattgcaacc gagagaattt tagaggttgg ttgaaaatgg
      541 ctaaaattgg ttatgcacgt gtcagtagca aagaacagaa cttagataga caactgaaag
      601 cgttagaggg cgtttctaag gtcttttcag acaaattaag cggtcaatcg gtcgaacgcc
      661 cacaattaca agctatgctt aactatattc gtgaagggga tatagttgtt gttactgaat
      721 tagatcgatt aggacgaaat aataaagaat taacagaatt gatgaatcaa attcaaatta
      781 agggggcaac cctggaagtc ttaaatttac cctcaatgaa tggtattgaa gatgaaaatt
      841 taagacggct gattaataat ttagtgattg aattgtataa gtaccaagcg gaatctgaac
      901 gcaaacgaat taaagaacgc caagcccaag gaattgaaat tgctaagaaa aaaggaaaat
      961 tcaaagggcg acaacctaaa ttcaaagaaa atgatccacg tttacaacac gctttcgatt
     1021 tatttttgaa tggttgttcc gataaagaag ttgaagaaca aactggaatt aatcgccgaa
     1081 cgtttagaag gtatcgatca agatacaacg tgacagtaga tcaaagaaaa aaacaatgaa
     1141 aagagggata gttaatgagt acggttattt tagctgaaaa accaagccag gcattagcct
     1201 acgcaagtgc tttaaaacaa agcaccaaaa aagacggtta ttttgagatc aaagacccac
     1261 tatttacaga tgaaacgttt atcacctttg gttttgggca tttagtcgaa ttagcagaac
     1321 caggtcatta taacgaaaag tggcagaact ggaaacttga atctttgccg atttttcctg
     1381 atcgatacga ttttgaagtt gcaaaagata agggaaagca gtttaaaatt gttgctgaac
     1441 ttctcaaaaa ggcaaataca attattgtcg caacagatag cgacagagaa ggtgaaaata
     1501 tcgcctggtc gattatccat aaagcaaatg ccttttctaa agataaaacg tataaaagat
     1561 tatggatcaa tagcttagaa aaagatgtga tccgaagcgg ttttcaaaat ttgcaaccag
     1621 gaatgaatta ctatcccttt tatcaagaag cgcaaacacg ccaaattgcc gattggttga
     1681 tcggcatgaa cgcaagccct ttatatacct tgaatttaca acaaaaaggc gtacaaggta
     1741 cattttcatt aggacgtgta caaacaccga ctttatatct catttatcaa cgccaggaag
     1801 caatagaaaa ctttaaaaaa gaaccttttt tcctgaataa ttcatagttt tactaatagt
     1861 ctttcctaac attgatttaa tagtctttaa agtattctgc ttcatcaccc attaggtgat
     1921 gaaaaaagaa cccctttctg atttagcgga caaatacttt gacctaatct cagaagatat
     1981 aaaagaaaaa ataataaaat atccgattta tactttgtat aaagaactaa agtagttagc
     2041 aaatcattta cagcaaatca ctatgttcca cataccattt tacatactta ccttatccac
     2101 gacacatgtt gagatagtat cgaagataaa gaaagttgct ccatgttgtt tttgcgagat
     2161 ggggaaatca aagccacatt gacaaccatg atgaataagc ttgctttcag tcataagcta
     2221 atcctagaac cacttttcaa gtcagttagc caaatcgatg aagaaagcga ccgtgaaaga
     2281 atggacgcta ttgataagct aatggagcaa ctattggaag aacgcaatac ccttattgca
     2341 ctgatgtcca aaggtttcct agaacctgct ctttttaatc aggaacgaaa tgttttagat
     2401 agtgagatta aaaatcttac taccgaaaaa acaaacctgg taacgaactc tgcgagtggg
     2461 gttttgcgag caaacgagat aaaggacctc attaattatg tgtcagcaga taattttaat
     2521 ggtgactaca cggaagaact atttgaagaa tttgtagtga acatcattgt aaattccagg
     2581 gatgagctga cattcaattt gaaatgcggt ctttccctga aagaaaaggt ggtgagataa
     2641 atggcatata ttccatatgg atacaaaatt caagatggag tggttactgt cgatgaaaag
     2701 gcagcaggtc aagtaaaggt attctttgag aaatacatat caggactatc ccttacagtg
     2761 gctggcgaac aggcaggtat tgaaaagaca cattctgtga tggggcgcat tttgaaaaac
     2821 gtcaactacc ttggaaatga tacgtatcca gcaattattg ataaagagat atttgataaa
     2881 gctgaagaag ttagagataa acgtgcaaag gatttaggac gagtggtaga gcttgccgct
     2941 ttcacctctc cccctcccaa agaacgattc aaaatgaaaa aggcagataa taagatgcca
     3001 gtggatcctt ttgaacgagc agaatactta tacagtctga tagaaagcga ggaataaagt
     3061 gacagagaaa aatataatgg ttattcctgc tcgtaaaaga gtaggaagta cagccgcaaa
     3121 agaaaagata aagaaacttc gtgttgctgc ctattgccgt gtttctacag aaacagaaga
     3181 acaaaattct agctatgagg ttcaggtctc acactataca gagtttataa agaaaaataa
     3241 tgaatgggag tttgctggca tctttgcaga tgatggtatc tctggtacga acactaaaaa
     3301 gcgtgacgaa tttaatcgca tgattgcaga gtgtatggac ggtaacatcg acatggttat
     3361 tacaaaatcc atcagccgat ttgcgcgtaa caccctagac tgccttcaat acattagaca
     3421 gctcaaggat aagaacatat cagtttattt tgagaaagag aacatcaaca ccacggatgc
     3481 caaaggtgag gttttgctga ctattatggc atctttggca cagcaggaaa gccagagcct
     3541 ttcacaaaac gttaagcttg ggctacagta ccgataccaa caaggaaagg tgcaggtcaa
     3601 ccataagcga tttatgggct acacgaaaga tgaagatgga aatttaacta ttgtccccga
     3661 agaagctgag attatcaaac gcatctaccg agaatacctt gagggtcaga gtctagtggg
     3721 cattggtcga gcccttgaaa aggatggtat tttaacagca gcgggaaaac caagatggcg
     3781 accagaatca gttaagaaga tacttcaaaa cgaaaaatac atcggagatg cccttctgca
     3841 aaagactgtc acagtagatt ttctgaccaa gaaacgagtg aaaaatgaag ggcatgttcc
     3901 ccaatattat gttgaaaata gccatgaagc gattattcct aaagagttat ttttgcaggc
     3961 gcaagaagaa attcatcgga gaagcaatat ctacacagga gaaggcaaga acaaaagaat
     4021 ttacagtagc aagtacgctt taagtgccat caccttctgt ggagattgtg gcgatattta
     4081 tagacgggtc tattggaata tccacggaag aaaagaattt gtctggcgat gcgtgactag
     4141 aatcgagcaa ggtcctgaag tttgtaagaa ccgaaccgta aaagaagatg aactttatgg
     4201 tgcagtaatg actgcgatta ataagctact tgcaggtggg aacaatatga taaagacact
     4261 ggaagagaat attcatgctg tgattggcga aaccacagaa taccaaattt cagagattaa
     4321 caactcacta gaggaaaaac aaaaagaact aatcaagctg gcgaacaagg gtcaagacta
     4381 tgaccactta gcagatgaga ttgatgagct gagagacaag cgacagatcc ttttagtaga
     4441 agatgcctcc ctcagtggcg agaacgagcg aatcaatgag ctgattgaat ttatccgcaa
     4501 gaacaaattc cgcaccttag aatatgatga taagcttgta aggaagataa tccagagcgt
     4561 tacagtctat gaaggccact tcgtcatagc cttcaaatct ggcatcgaaa tggaaatatg
     4621 aaaaccagaa gtaaatagcc catgactcta cagtagagtt gtgggttttc ttttgcttgc
     4681 tgattataat aatattttaa taactattgt gtttatcaac caaatggttt ataatattct
     4741 tagcgtaaac ttggaggtgc tgtatgacta cggcagaaat gattaaagaa ctgtgtgagc
     4801 aaatgaatat aagtgtttcc gaacttgcta gacgtattgg ccagactcca cagaatttca
     4861 ataaaaaatt acaacgagaa acagtaacct tggatgagtt gaaggccatt gctgatgtgc
     4921 taggtgtcaa gtttgtgcag gcatttattt taccagatgg agaagaaata aaaatatcta
     4981 acgaataaag gaggatgttt atatggtagg taatgttatt caaatagtaa cagagaaatt
     5041 atcatctttg ccttttatag aaggcatcgt attagggggc tcacgtgcaa gaggcaccca
     5101 tacagaaaat tctgatatag atatcggaat ctattacaat tcagactcat ttgacctgac
     5161 agcgattaat caaattgcta cagagttgga tgatgagaat agaaacaacc ttgttgtacc
     5221 tcccggagcg tggggtgatt gggttaatgg cggtggatgg ttagttataa acgggtgtca
     5281 tgttgacttg atattacgtg atataaaacg ggtggaacaa ataatcaaag atacggagca
     5341 aggaattgtt actgccaatt atcagaccgg gcatccccat ggttatataa gtgctatgta
     5401 tcgtggagaa ttagcgatta gtaaaatact atatgctaag aacgaaagct tatgcgaatt
     5461 aaaaaagcag gcagaaattt accctactgc tctaaagaaa agcttgatga acttttttat
     5521 atttgaagct gaattctctt taatgtttgt aaaagcaaat gcgggggcag aggataaata
     5581 ttatattgca ggccatgttt ttcgtattat ttcatgctta aatcaagtac tatttgcatg
     5641 taataatgct tattgcatta acgaaaagaa agctataaaa ctgcttgaaa cttttgaata
     5701 taaacctgaa aaatatgccg aaagagttaa tcatattttt gaagtactcg gtctttctct
     5761 ttttgaatgc tacgacatga ccgagaaact ttataaagaa gtgaatgaaa ttgtatcgga
     5821 gataaataac tttttaaacg aggagagttc agatgaaaga aaacaaatat gatgataata
     5881 tattttttca aaaatacagt caaatgagtc gctcgcagaa aggactggct ggtgcgggag
     5941 aatgggagac tttgaaaaag atgctacctg attttaaggg taagcgtgtg cttgatttag
     6001 gatgcggcta tggatggcac tgtatatatg cgatggaaaa cggtgcttcc tctgtagtag
     6061 gtgttgatat ttctcataaa atgctcgaag tagcaaaagg aaaaacccat tttccacaga
     6121 ttgaatatga atgctgtgcc atagaagatg tggatttccc agaggagagc tttgatgtaa
     6181 tactaagttc gcttgcgttt cattatgtag cagactatga gaatttaata aaaaagatat
     6241 ataggatgct gaaggctggt ggcaatttag tttttacagt tgaacatcct gtttttactg
     6301 ctcatggaac acaagactgg tattataacg aaaaaggaga aatactgcat ttcccggtgg
     6361 acaattatta ttatgagggc aaacggacag ctatgttttt ggaagaaaag gttacaaaat
     6421 atcatagaac actgaccaca tatctaaata cactgctttc aaatagtttt ataataaatc
     6481 agattgtgga gccacagccg ccagagaaca tgatggatat tccggggatg gcggatgaaa
     6541 tgcgacgccc aatgatgctg attgtatcgg caaaaaagaa gatgtaataa tatagaaaaa
     6601 ataaacgagg agtatgtaaa tgagatcaga aaaagaaatg atggatttag tactttcttt
     6661 agcagaacag gatgaacgta ttcgaattgt gacccttgag gggtcacgcg caaatattaa
     6721 tatacctaaa gatgaatttc aggattatga tattacatat tttgtaagtg atatagaacc
     6781 gtttatatct aatgatgact ggcttaatca atttgggaat ataataatga tgcaaaagcc
     6841 ggaggatatg gaattattcc cacctgaaga aaagggattt tcctatctta tgctatttga
     6901 tgattacaat aaaattgatc ttaccttatt gcccttggaa gagttagata attacctaaa
     6961 gggcgataaa ttaataaagg ttctaattga taaagattgt agaattaaaa gggacatagt
     7021 tccgactgat atagattatc atgtaagaaa gccaagcgca agggagtatg atgattgctg
     7081 caatgaattt tggaatgtaa caccttatgt tattaaagga ttgtgccgta aggaaatttt
     7141 atttgctatt gatcatttta atcagattgt tcgccatgag ctgctgagaa tgatatcatg
     7201 gaaggtcggc atcgaaacag gctttaaatt aagtgtaggc aagaactata agtttattga
     7261 aaggtatata tccgaggatt tgtgggagaa acttttgtcc acctaccgga tggattccta
     7321 tgaaaacata tgggaagcat tatttctatg ccatcaattg ttcagggcgg tatccggtga
     7381 ggtggcggaa aggcttcatt atgcctatcc ggagtatgat aggaatataa caaaatatac
     7441 cagggacatg tataaaaaat acactggtaa aaccggctgc ctggatagca catatgccgc
     7501 tgatatagaa gagaggcggg aacagtgatt acagaaatga aagcagggca cctgaaagat
     7561 atcgataaac ccagcgaacc atttgaggtg ataggtaaga ttataccgag gtatgaaaac
     7621 gagaattgga cctttacaga attactctat gaagcgccat atttaaaaag ctaccaagac
     7681 gaagaggatg aagaggatga ggaggcagat tgccttgaat atattgacaa tactgataag
     7741 ataatatatc tttactacca agacgataaa tgcgtcggaa aagttaaact gcgaaaaaat
     7801 tggaaccggt acgcttatat agaagatatc gccgtatgta aggatttcag ggggcaaggc
     7861 ataggcagcg cgcttatcaa tatatctata gaatgggcaa agcataaaaa cttgcatgga
     7921 ctaatgcttg aaacccagga caataacctt atagcttgta aattctatca taattgtggt
     7981 ttcaaaatcg gctccgtcga tactatgtta tacgccaact ttgaaaacaa ctttgaaaaa
     8041 gctgttttct ggtatttaag gttttagaat gcaaggaaca gtgaattgga gttcgtcttg
     8101 ttataattag cttcttgggg tatctttaaa tactgtagaa aagaggaagg aaataataaa
     8161 tggctaaaat gagaatatca ccggaattga aaaaactgat cgaaaaatac cgctgcgtaa
     8221 aagatacgga aggaatgtct cctgctaagg tatataagct ggtgggagaa aatgaaaacc
     8281 tatatttaaa aatgacggac agccggtata aagggaccac ctatgatgtg gaacgggaaa
     8341 aggacatgat gctatggctg gaaggaaagc tgcctgttcc aaaggtcctg cactttgaac
     8401 ggcatgatgg ctggagcaat ctgctcatga gtgaggccga tggcgtcctt tgctcggaag
     8461 agtatgaaga tgaacaaagc cctgaaaaga ttatcgagct gtatgcggag tgcatcaggc
     8521 tctttcactc catcgacata tcggattgtc cctatacgaa tagcttagac agccgcttag
     8581 ccgaattgga ttacttactg aataacgatc tggccgatgt ggattgcgaa aactgggaag
     8641 aagacactcc atttaaagat ccgcgcgagc tgtatgattt tttaaagacg gaaaagcccg
     8701 aagaggaact tgtcttttcc cacggcgacc tgggagacag caacatcttt gtgaaagatg
     8761 gcaaagtaag tggctttatt gatcttggga gaagcggcag ggcggacaag tggtatgaca
     8821 ttgccttctg cgtccggtcg atcagggagg atatcgggga agaacagtat gtcgagctat
     8881 tttttgactt actggggatc aagcctgatt gggagaaaat aaaatattat attttactgg
     8941 atgaattgtt ttagtaccta gatttagatg tctaaaaagc tttaactaca agctttttag
     9001 acatctaatc ttttctgaag tacatccgca actgtccata ctctgatgtt ttatatcttt
     9061 tctaaaagtt cgctagatag agttctatat tagagatgta aagagttttg gtgaagaggt
     9121 ttgtgagtat ggcttttata accagggtgc aatgagaagc actaacagca gctagcttaa
     9181 gaacgcatag gatatacttt ttatggaagt cacagaggag gaataaaatt tgaacaggat
     9241 taacagagta acctctattc ttattcagct gcaatcaaaa aaaataattc ctgccaaaga
     9301 aattgcacag cgatttaata taagcttaag gacagtttac agagatatcc ggacacttga
     9361 agaagccgga ataccaattg gatctgaggc cggaaaagga tattttcttg tagagggctt
     9421 cctacttccg ccggtaatgt ttacagcggc ggaagtgggt gcattgatta cagcagggaa
     9481 atttttaaat tgccatggag atgaatcatt tataaaggat tttgattcag ctatgtataa
     9541 aatcaaatct attttgaagc atggtgaaaa aaactatgca caggagttgg agaacagtat
     9601 taacgtgtac agcacatctg gacagaaaaa tacattggcg gataacgtta ttgcagcaat
     9661 tcagactgca atctgcaata aaagggtaat atcaattcaa tatcctgcat caggagggca
     9721 agaaccggaa agcagaatga tagagcctat atcactgggg ttttatgaac agaactggta
     9781 cttaatcggt tttgcaggct aagaaatgaa tataggaatt ttcgtgtgga tcggattaaa
     9841 agcatttgca tagaagaaga gctctgtcaa agccatgatg gctctttgga acaaatatta
     9901 aaacaaatgc tttcatataa aaaactatat gccctacaat gccgttgtaa aaattgggga
     9961 aaagggatat attgatttta tatctttctc aaaataaata taaaagccct ttaaagaggg
    10021 cttttatata ttaatcacaa atcacttatc acaaatcaca agtgattaat cacaaatcac
    10081 ttgtgat
//
LOCUS       DADGKS010000354         9328 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.guided.095, whole genome shotgun sequence.
ACCESSION   DADGKS010000354 DADGKS010000000
VERSION     DADGKS010000354.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9328
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.guided.095"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..1066
                     /locus_tag="JXV47_003371"
     CDS             <1..1066
                     /locus_tag="JXV47_003371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAX1489311.1"
                     /translation="KRAITKLFNTILTRAGITLIITTAFSISTMLYTLSAGYPFFLIA
                     FLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRVMRKPRMLMHAHMHRLQRKLGRSM
                     TTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGKEKSTLGKRIGQTIGTVADTKDRM
                     VDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRDLTSSISQTKADRASGRKEQQEQR
                     RKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQYHDEQTSKQSNIQTSYKESQQAKQ
                     ERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTTADRTSQRPITKERPSTVQRVPLQ
                     NTRSRPPIKTATIKKVGKKP"
     gene            1063..2064
                     /locus_tag="JXV47_003372"
     CDS             1063..2064
                     /locus_tag="JXV47_003372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAX1489312.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            2061..2996
                     /locus_tag="JXV47_003373"
     CDS             2061..2996
                     /locus_tag="JXV47_003373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAX1489313.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            3241..3357
                     /locus_tag="JXV47_003374"
     CDS             3241..3357
                     /locus_tag="JXV47_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HAX1489314.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            3373..5292
                     /gene="tet(M)"
                     /locus_tag="JXV47_003375"
     CDS             3373..5292
                     /gene="tet(M)"
                     /locus_tag="JXV47_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019117172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HAX1489315.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDRGTTKTD
                     NTLLERQRGITIQTAITSFQWKNTKINIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKIGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     HPNMRVMNFTESEQWDMVIEGNDYLLEKYTSGKLLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     PLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            5411..5578
                     /locus_tag="JXV47_003376"
     CDS             5411..5578
                     /locus_tag="JXV47_003376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAX1489316.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(5638..5991)
                     /locus_tag="JXV47_003377"
     CDS             complement(5638..5991)
                     /locus_tag="JXV47_003377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1489317.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            6496..6918
                     /locus_tag="JXV47_003378"
     CDS             6496..6918
                     /locus_tag="JXV47_003378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAX1489318.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            6915..7145
                     /locus_tag="JXV47_003379"
     CDS             6915..7145
                     /locus_tag="JXV47_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1489319.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            7606..7809
                     /locus_tag="JXV47_003380"
     CDS             7606..7809
                     /locus_tag="JXV47_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HAX1489320.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            7891..9108
                     /locus_tag="JXV47_003381"
     CDS             7891..9108
                     /locus_tag="JXV47_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAX1489321.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
BASE COUNT         3182 a         1617 c         1890 g         2639 t
ORIGIN      
        1 aaaacgagcc ataacaaagc tctttaatac cattttgaca cgagctggaa tcacattgat
       61 tattacgaca gcatttagta tttcaaccat gctctatacc ttatcggctg gttatccgtt
      121 ctttttgatt gcttttctac agattgtgac ctttgcagga atctacttca agctgggcga
      181 tttaatgagt atgttttctc tacagagtaa cgattctcaa agtgtgggaa gtcgtgtgat
      241 gagaaaacct cgtatgctta tgcacgctca catgcaccgt ctacagcgga aacttggacg
      301 ttccatgact actctagggg ctgggtctgc cattgttaca ggtaaaaaag gacagtcggg
      361 ttcggggagt tctgcaagga cacaagcaga tcactcccga ccagacggaa aggaaaaatc
      421 aacacttgga aaacgtatcg gtcaaaccat cggtacagta gctgatacca aagacagaat
      481 ggtagacact gctagtggtt tgaaagaaca ggttaaagat ttgccgacca atgcaagata
      541 tgcagtatat caaggaaaat ccaaagtaaa agagaatgtc cgtgatttaa ccagtagtat
      601 ttctcaaacc aaagcggaca gagccagtgg acgcaaggaa cagcaggaac aaaggcgaaa
      661 aaccattgcg aagcgtcgct ctgaaatgga acaggtcaaa cagaaaaaac agcctgcttc
      721 ttctgttcat gaaagaccga ctacaagaca agaacaatat catgatgaac agacctcaaa
      781 acagtctaat attcagactt catataagga atctcaacaa gccaaacaag agcgtccagc
      841 agttaagtcc gatttttcaa gtccaaaagt ggaacgccaa ggcaataccg ttcaagaaaa
      901 aaccgttcaa aagccagcaa cttcaaccac tacagcagat agaacttcac aacgtccaat
      961 cacaaaagaa cgtccgtcta ctgttcaaag agtaccacta caaaatacaa gaagtagacc
     1021 accaatcaaa accgccacca ttaagaaagt cggtaagaaa ccatgaagtt gaaaacttta
     1081 gtgattggtg gttctggatt attcttgatg gtcttctcac tgcttctgtt tgttgccatt
     1141 ttattttcag atgaacagga cagcggaatt tccaatattc attatggagg tgtgaatgtt
     1201 tccgcagaag tgctggctca taagcctatg gtagaaaaat atgccaaaga atatggcgtt
     1261 gaagaatatg tcaacatact tcttgcgatt atacaggtgg aatcgggcgg tactgcggaa
     1321 gatgttatgc agtcctcgga atccctcggt cttccaccta attcattgag tacagaagaa
     1381 tccattaagc aaggtgtgaa gtatttcagt gaattattag ccagtagcga aaggctcagt
     1441 gtagatttag aatcggttat ccagtcctac aattatggtg gtggtttctt agggtatgtg
     1501 gctaatcgtg gaaataaata tacctttgaa ctggctcaaa gtttctcaaa agagtattca
     1561 ggtggcgaaa aagtgtctta ccccaatccc atagccatac ctatcaatgg gggctggcga
     1621 tacaactatg gcaatatgtt ttatgtgcaa ctggtaacgc agtatcttgt cacaacagag
     1681 tttgatgatg atacggtaca agccatcatg gacgaagcac tgaaatatga gggctggcga
     1741 tacgtttacg gtggagcttc cccgactact tcttttgatt gtagcggact gacacaatgg
     1801 acgtatggaa aagctggaat taacttacca cgaaccgcac aacagcaata tgatgtgacc
     1861 cagcatatcc cactatcgga agcacaagct ggcgatttgg ttttctttca ttctacctat
     1921 aacgctggct cttatattac tcatgttggg atataccttg gcaataaccg tatgtttcat
     1981 gcaggcgacc caatcggtta tgccgactta acaagcccct actggcaaca gcatttagtg
     2041 ggagcaggac gaatcaaaca atgagaaagg aagatttaat gatgaaattt agaaaaaatc
     2101 agaataaaga aaaacagata ccaaaggaaa agaaacctcg tgtctactat aaggtcaatc
     2161 ctcataaaaa ggttgtgatt gccttgtggg tacttttagg gcttagtttc agctttgcga
     2221 tattcaagca ctttacagct atagatactc atactattca cgaaacaact atcatagaaa
     2281 aggaatacgt tgatactcat catgtagaaa attttgtaga gaactttgcg aaagtctact
     2341 attcatggga gcaatccgat aagtccattg ataatcgaat ggaaagtcta aaaggctatc
     2401 tgacagatga acttcaagct ctcaatgttg atacagtacg caaagatatt cctgtatcgt
     2461 cttctgtaag aggatttcag atatggacgg tagagccaac tggcgacaat gagtttaatg
     2521 taacctacag tgtagaccag ctcattacag agggagaaaa tacaaagacc gtccactctg
     2581 cttatatagt gagtgtctat gtagatggtt ctggaaatat ggtactggtt aagaatccga
     2641 ccattaccaa catacctaag aaatcaagtt ataaaccaaa agccattgaa agtgagggga
     2701 cggttgattc cattacaacc aatgaaatca atgagttttt aacgacgttc ttcaagctct
     2761 atcctacagc gacagccagt gaactttcct actatgtgaa tgacgggata ttaaaaccaa
     2821 tcggaaaaga gtacatcttt caagaactgg taaatcctat tcacaatcgt aaggataatc
     2881 aagtcacggt atcgctgaca gtggagtata tcgaccagca gaccaaagca acgcaggtat
     2941 ctcaatttga tttggtactt gaaaagaacg ggagtaattg gaagattata gaataacaaa
     3001 tattggtaca ttattacagc tattttgtaa tcacgtactc tctttgataa aaaattggag
     3061 attcctttac aaatatgctc ttacgtgcta ttatttaagt atctatttaa aaggagttaa
     3121 taaatatgcg gcaaggtatt cttaaataaa ctgtcaattt gatagtggga acaaataatt
     3181 ggatgtcctt ttttaggagg gcttagtttt ttgtacccag tttaagaata cctttatcat
     3241 gtgattctaa agtatccgga gaatatctgt atgctttgta tgcctatggt tatgcataaa
     3301 aatcccagtg ataagagtat ttatcactgg gatttttatg cccttttggg cttttgaatg
     3361 gaggaaaatc acatgaaaat tattaatatt ggagttttag ctcatgttga tgcgggaaaa
     3421 actaccttaa cagaaagctt attatataac agtggagcga ttacagaatt aggaagcgtg
     3481 gacagaggta caacgaaaac ggataatacg cttttagaac gtcagagagg aattacaatt
     3541 cagacggcga taacctcttt tcagtggaaa aatactaaga taaacatcat agacacgcca
     3601 ggacatatgg attttttagc agaagtatat cgttcattat cagtattaga tggggcaatt
     3661 ctactgattt ctgcaaaaga tggcgtacaa gcacaaactc gtatattgtt tcatgcactt
     3721 aggaaaatag gtattcccac aatctttttt atcaataaga ttgaccaaaa tggaattgat
     3781 ttatcaacgg tttatcagga tattaaagag aaactttctg cggaaattgt aatcaaacag
     3841 aaggtagaac tgcatcctaa tatgcgtgta atgaacttta ccgaatctga acaatgggat
     3901 atggtaatag aaggaaatga ttaccttttg gagaaatata cgtctgggaa attattggaa
     3961 gcattagaac tcgaacaaga ggaaagcata agatttcata attgttccct gttccctgtt
     4021 tatcacggaa gtgcaaaaaa caatataggg attgataacc ttatagaagt gattacgaat
     4081 aaattttatt catcaacaca tcgaggtcag tctgaacttt gcggaaaagt tttcaaaatt
     4141 gagtattcgg aaaaaagaca gcgtcttgca tatatacgtc tttatagtgg cgtactgcat
     4201 ttgcgagatt cggttagaat atcggaaaag gaaaaaataa aaattacaga aatgtatact
     4261 tcaataaatg gtgaattatg taaaatcgat aaggcttatt ccggggaaat tgttattttg
     4321 cagaatgagt ttttgaagtt aaatagtgtt cttggagata caaagctatt gccacagaga
     4381 gagagaattg aaaatcccct ccctctgctg caaacgactg ttgaaccgag caaacctcaa
     4441 caaagggaaa tgttacttga tgcactttta gaaatctccg acagtgaccc gcttctgcga
     4501 tattatgtgg attctgcgac acatgaaatc atactttctt tcttagggaa agtacaaatg
     4561 gaagtgactt gtgctctgct gcaagaaaag tatcatgtgg agatagaaat aaaagagcct
     4621 acagtcattt atatggaaag accgttaaaa aaagcagagt ataccattca catcgaagtt
     4681 ccaccgaatc ctttctgggc ttccattggt ctatctgtag caccgcttcc attagggagc
     4741 ggagtacagt atgagagctc ggtttctctt ggatacttaa atcaatcgtt tcaaaatgca
     4801 gttatggagg ggatacgcta tggctgtgaa caaggattgt atggttggaa tgtgacggac
     4861 tgtaaaatct gttttaagta tggcttatac tatagccctg ttagtacccc agcagatttt
     4921 cggatgcttg ctcctattgt attggaacaa gtcttaaaaa aagctggaac agaattgtta
     4981 gagccatatc ttagttttaa aatttatgcg ccacaggaat atctttcacg agcatacaac
     5041 gatgctccta aatattgtgc gaacatcgta gacactcaat tgaaaaataa tgaggtcatt
     5101 cttagtggag aaatccctgc tcggtgtatt caagaatatc gtagtgattt aactttcttt
     5161 acaaatggac gtagtgtttg tttaacagag ttaaaagggt accatgttac taccggtgaa
     5221 cctgtttgcc agccccgtcg tccaaatagt cggatagata aagtacgata tatgttcaat
     5281 aaaataactt agtgtatttt atgttgttat ataaatatgg tttcttgtta aataagatga
     5341 aatatttttt aataaagatt tgaattaaag tgtaaaggag gagatagtta ttataaacta
     5401 caagtggata ttgtgtcctg tatgtggaaa taaaacacga ttaaagataa gggaagatac
     5461 tgaattaaaa aaattccccc tctattgtcc gaaatgcaga caagaaaatt taattgaaat
     5521 aaagcagttc aaagtaactg tgattacaga gccagacgca aagacgcaga gccgataaaa
     5581 tgagattaat acaatctcat tttatcggct ctttccgtta tgtatggatt cttttaatta
     5641 gtcttcgatg tttcttgctt cgttgatacc gctggctaaa gattccatta aggatagttc
     5701 tttgtctgta aagctatcca tgtatttctc tatctgtaat cgtcgggtgc tttttaccaa
     5761 gttattagca ggtaagaaaa attcatcaac ggaaacatga agtaacgata caaggtcata
     5821 aagaacttgt atgctggggt gttgcccttt attttcaata ttagttaagt accgtgggtc
     5881 aatttcaatc aatgctccca cttgttcacg agttaaacct cgtttcaatc gagcttcttt
     5941 aatggctaaa ccaaaggctc taaaatcata tttatcttct tttttacgca tagtagacca
     6001 cctctataca ttttattgtt cctactgaat taaaaacagg tatagaaaaa cgtgttatat
     6061 ggtttatagg tttatattta ataaaaagca ctactaaacg ccaataaaaa aaaccgttat
     6121 atggtagtgc tatttacgct gttaaaatat tgtatattac ttccaaatgg cggtttgttg
     6181 gaggtcaacg tcgccatgaa gtacatcata tacaataaat ttccttacat tgggttcttg
     6241 tcaaaaaaag tcgtctatct gcaatagata agtacgtcca ccaatgtggt tttataaatc
     6301 atatagatag aataacagaa gcatgtaaac agagaaataa atctgtttat atgctttttt
     6361 ggctattcag aactttttta caaagtttat ttatcagtaa tgcaacaaat ccccctttca
     6421 cattgggact aagagtgaaa ggagataaac gagcaaggct cacttccttt cctagacaga
     6481 aagggggtga gaaacatgaa accatcttct tttcagacca caatagaaaa tcagtttgac
     6541 tatatctgta aacgtgctat ggaagacgag cgaaagaatt atatgcttta tctttcaagg
     6601 attgcaaagc gtgaggtgtc cttttcggat gttggcgatt atcttgttag ccagtttgcg
     6661 acaacagata actattcaac tgactttcag atttttacac tcaatgggtt atcagtaggc
     6721 gttgaaaatg atttgttgag tgaagcatta cgtgagttgc cagacaagaa acgtgaaatt
     6781 ctactgctgt tttactttat ggacatgagc gattcagaaa ttgcagacct gttgaaattg
     6841 aaccgttcta ctgtctatcg gcatagaacc agtggactag ccttaattaa aaagtttatg
     6901 gaggaatttg aagaatgaaa acacaatatc ctatgattcc ctttcctctc attgtaaagg
     6961 caacagatgg cgataccgaa gcgattaacc agattctaca tcattacaga gggtacataa
     7021 cgaagcgttc cctacgactt atgaaagatg aatatggcaa tcaaagtatg gtcgttgatg
     7081 aagtcttacg tggaagaatg gaaaccagac tgattacaaa gattttgtca tttgaaatta
     7141 agtaatatcc tctctccttt cgtggaagcg tgctaaacca ttccacgctt cccgaacagg
     7201 gaggtttgtt attccaccaa agcatattga gctttcaatg tgttttgata ggctaacgag
     7261 ccattgttct ttgaaaactg aataaaagta atcgaatacg tttcgataag aaaagagcca
     7321 acggaactaa ccgccatgac ctatcttata aagatagcga gcgattcatg ttagtgatcc
     7381 gagaagcaat ctttagcagg attgcctgca acgacattct tatcgtgata atgatactcc
     7441 catacagtca atagtccgag cgtgataaaa ccgtcgcagg caatgagtat ggctacatga
     7501 gaaccatgca ggggtggaac tcccgtgagc tttgctaaag ctgttcgatt gctggtaaaa
     7561 caacttttat gaaatccaaa taagtgattt ggaaaggagg attttatgaa gcagactgac
     7621 attcctattt gggaacgtta taccctaacc attgaagaag cgtcaaaata ttttcgtatt
     7681 ggcgaaaaca agctacgacg cttggcagag gaaaataaaa atgcaaattg gctgattatg
     7741 aatggcaatc gtattcagat taaacgaaaa caatttgaaa aaattataga tacattggac
     7801 gcaatctagc gtcgccaaag ggtcttgtat atgataaaat agtattaagt cgtatcaagg
     7861 ctctttccat aaaggaaagg agcaaatgcc atgtcagaaa aaagacgtga caataaaggt
     7921 cgaatcttaa agactggaga gagccaacga aaagacggaa gatacttata caaatatata
     7981 gattcatttg gagaaccgca atttgtttac tcgtggaaac ttgtggctac agaccgagta
     8041 ccagcaggaa agcgtgattg tatctcactt agagagaaaa tcgcagagtt acagaaagac
     8101 attcatgatg gtattgatgt tgtaggaaag aaaatgacac tctgccagct ttacgcaaaa
     8161 cagaacgctc aaagaccaaa ggttagaaaa aacactgaaa ctggacgcaa atatcttatg
     8221 gatattttga agaaagacaa gttaggtgta agaagtattg acagtattaa gccatcagac
     8281 gctaaagaat gggctattag aatgagtgaa aatggttatg cttatcaaac catcaataac
     8341 tacaaacgtt ctttaaaggc ttcattctat attgctatac aagatgattg tgttcggaag
     8401 aatccatttg actttcaact gaaagcagtt cttgatgatg atactgtccc taagaccgta
     8461 ctaacagaag aacaggaaga aaaactgtta gcctttgcaa aagctgataa aacctacagc
     8521 aaaaattatg atgaaattct gatactctta aaaacaggtc ttcgtatttc agagtttggt
     8581 ggtttgacac ttccagattt agattttgag aatcgtcttg tcaatataga ccatcagcta
     8641 ttgagagata ctgaaattgg gtactacatt gaaacaccaa agaccaaaag tggcgaacgt
     8701 caagttccta tggttgaaga agcctatcaa gcatttaagc gagtgttagc gaatcgaaag
     8761 aatgataagc gtgttgagat tgatggatat agtgatttcc tctttcttaa tagaaagaac
     8821 tatccaaaag tggcaagtga ttacaacggc atgatgaaag gtcttgttaa gaaatacaat
     8881 aagtataacg aggataaatt gccacacatc actccacata gtttgcgaca tacattctgt
     8941 accaactatg caaatgcagg aatgaatcca aaggcattac agtacattat gggacatgct
     9001 aatatagcca tgacgctgaa ctattacgca catgcaacat tcgattctgc aatggcagaa
     9061 atgaaacgct tgaataaaga gaagcaacag gagcgtcttg ttgcttagta gtacaaatga
     9121 atttactact tatttaccac ttctgacagc taagacatga ggaaatatgc aaagaaacgt
     9181 gaagtatctt cctacagtaa aaatactcga aagcacatag aataaggctt tacgagcatt
     9241 taagaaaata taaaaagata attagaaatt tatactttgt ttaagtataa aaaatgaaaa
     9301 aatacgagca gaaaactgtt ttatctgc
//
LOCUS       DADGKS010000355         7958 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.guided.110, whole genome shotgun sequence.
ACCESSION   DADGKS010000355 DADGKS010000000
VERSION     DADGKS010000355.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7958
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.guided.110"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            128..1564
                     /locus_tag="JXV47_003382"
     CDS             128..1564
                     /locus_tag="JXV47_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAX1489322.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            1753..4200
                     /locus_tag="JXV47_003383"
     CDS             1753..4200
                     /locus_tag="JXV47_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAX1489323.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            4430..5497
                     /gene="rlmN"
                     /locus_tag="JXV47_003384"
     CDS             4430..5497
                     /gene="rlmN"
                     /locus_tag="JXV47_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HAX1489324.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(5690..6793)
                     /locus_tag="JXV47_003385"
     CDS             complement(5690..6793)
                     /locus_tag="JXV47_003385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAX1489325.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7345..7893
                     /gene="aac(6')"
                     /locus_tag="JXV47_003386"
     CDS             7345..7893
                     /gene="aac(6')"
                     /locus_tag="JXV47_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAX1489326.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2665 a         1359 c         1729 g         2205 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacataa ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     1081 aatgaatacg acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag
     2521 caaagggaaa atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta
     2581 agttttgttc caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca
     2641 gtaccagata caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag
     2701 gatgacggta cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa
     2761 ttaccgacag ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa
     2821 aaaattgaaa aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc
     2881 aaggtcgtca aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta
     2941 ggggtaaaag taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg
     3001 aaagatgtcc ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca
     3061 aatggaaaga tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca
     3121 gataaattac tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat
     3181 ctttcgaaga tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca
     3241 attaatggga ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg
     3301 atgatcgatc cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg
     3361 ccggtcgtga cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg
     3421 gaagaacgat atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa
     3481 tttgttcaac agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta
     3541 gtgatcgtag atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg
     3601 attattcgtt tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa
     3661 cgtccaagtg tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca
     3721 tttgcggtat caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag
     3781 ctcttagggc gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg
     3841 caaggagcat tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag
     3901 caagaagctc attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct
     3961 ccagaacagc cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa
     4021 acggcaagta tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt
     4081 ttagtagatg aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg
     4141 aaagtattca ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa
     4201 aacttgtgtg atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata
     4261 ccaaaagaaa aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt
     4321 agtttttgtg agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg
     4381 aatcatgtat agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca
     4441 gtccatttat ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa
     4501 aaaattccga gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac
     4561 agaaatgacg aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa
     4621 tcctctaaaa cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga
     4681 actccctgat aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt
     4741 ttgtgtgacg acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct
     4801 caaaaagaac cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca
     4861 ttattttgat gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg
     4921 tgagccattt gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa
     4981 aggattggca attggtgctc ggcacattac agtttccact agtggattag cacacaaaat
     5041 caaggaattc gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa
     5101 taatgaggtg cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat
     5161 ggaagctgtg gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat
     5221 gttgaatcaa gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga
     5281 taagaaaaaa ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca
     5341 atattctcgc agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg
     5401 cgtaaactgt gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt
     5461 gcgaagcaag caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa
     5521 ttaccataaa aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag
     5581 attctatagc gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa
     5641 atgtcctcaa tttgatgaca gcctgcttga tgggggtttt agcaattatt taactgattt
     5701 tcttatatcc ttgctggctt tcttgtgtag catgataagt ttctacgtca agaatggcct
     5761 gtttaaattt ttctcgggtg atttcataag gcacatgttt aatatcattt gttgccatgg
     5821 ctttatctaa gattgcttct aaatcggtcg tgacattgag attcatgtcg gttaacgata
     5881 ctggaagttg gttctttttc ataaacacat agattttatc aaacaaatcg aactgctgat
     5941 ccatcatcaa taaggtcagt acaccataac tgacagatgc tccgtgaagg tatccctcca
     6001 ttttttctag aacagtcgta ccgtaataga atgagtgtgc catagcagaa ttatagttat
     6061 tgttaactaa aacagaaacc aatccggtag taacaatgat atccgaaacg acttgttcaa
     6121 ttgcatatga gggacgatcg tcggcactat ctttcaatgc ttgcgtacca taagtcaaga
     6181 gacgatcaat gcacattttt ccgatttgga ttcctaatct atccgtgtag cctagatcat
     6241 cgccacgagc agaaaaagta gattcgactt ctttggataa agcatcgcca atacctgccc
     6301 ataagtattt atcaggtgct tcggcaataa ttgctgtatc aatgaaggtg tgtacaggtg
     6361 gttttgaagg aaagaagagt ccgtccatta cgccttcttc gttatagatg acacataccg
     6421 cagtgacggg cgaacagttc gaaccaatag tgggaaaggt gaagactggt ttagctagtt
     6481 tttcaccaat gacttttaca gtatcgcaag cacggccacc accgactgca aacaggacgt
     6541 ctgctttttg gacactttca tgctggatca actgttcaat atttccataa gttgaattac
     6601 ccccgtacca gagactggcg acaacctcta tttcctgtgt caaagctact tttattttgt
     6661 tttctgcctt tgaaagtgca gtcttccctc caatcagcac tacttttgtc ccatattctt
     6721 tgacgattcc atttgctttt tcatacgcat ctgttccaat ggtataattt ggtaagaaaa
     6781 cactttgact catattcatt tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag
     6841 tgatcgatct gactgcggct gtagatggag tagaggtgaa cctaagacag gataagtgat
     6901 gaataaggtg gcatgaacac cttgaaatca tcaataagta tcctaaaaac gaacaagtac
     6961 aaaaacattg aaaacgacaa taatgaattt ttgttcctct tagtatttct accgattccc
     7021 tttgcttttt tgtaattatc taaaaattct aaaaattaag attattatat gaaaacaggt
     7081 tttatttgtc aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga
     7141 acaaacagag ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag
     7201 tgtttctgta taatttttta ttttataagt aagataaata atgaaagaat agagatactg
     7261 attggtagct aaagattttt gagcgagaac atttcgtttt ttcaaaagga ctgttagaat
     7321 aagcaagaac aagggggaag acgtatgata atcagtgaat ttgaccgtaa taatccagta
     7381 ttgaaagatc agctttctga tttactgaga ctgacttggc cggaagaata tggagacagc
     7441 tcggcagaag aagtagaaga aatgatgaat ccagaacgaa tcgcggtagc agcggtagac
     7501 caagatgagt tagtaggatt tattggtgca atccctcaat acggtatcac aggttgggaa
     7561 ttgcatccat tagttgtaga aagctcccga cgaaagaacc aaataggtac tcgattagtc
     7621 aattacttag aaaaagaagt agcttccaga ggaggaatca cgatttattt aggtacggat
     7681 gatttagacc atggaacaac gttaagtcaa acggacctgt atgagcatac atttgataaa
     7741 gtggcttcca tccagaacct tcgtgaacat ccgtatgaat tctatgaaaa attaggttat
     7801 aaaatcgtag gtgtcttacc aaatgcaaat ggctgggaca aaccggatat ttggatggca
     7861 aaaacgatta ttcctcgacc aaattctcaa taataaaaag aggttgtgac agaagtaatc
     7921 agcttcaaga aataagaagg aatttacgaa aattactt
//
LOCUS       DADGKS010000356         4873 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.guided.155, whole genome shotgun sequence.
ACCESSION   DADGKS010000356 DADGKS010000000
VERSION     DADGKS010000356.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4873
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.guided.155"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            363..860
                     /gene="dfrG"
                     /locus_tag="JXV47_003387"
     CDS             363..860
                     /gene="dfrG"
                     /locus_tag="JXV47_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HAX1489327.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(932..2884)
                     /locus_tag="JXV47_003388"
     CDS             complement(932..2884)
                     /locus_tag="JXV47_003388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HAX1489328.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2891..3187)
                     /locus_tag="JXV47_003389"
     CDS             complement(2891..3187)
                     /locus_tag="JXV47_003389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489329.1"
                     /translation="MQIGVLKWLQFTKQKGVHFPMQFLEPKNKNAKSVDWEISEQVRV
                     IVKQYAEYAERTESEAVDEFLLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            3529..3819
                     /locus_tag="JXV47_003390"
     CDS             3529..3819
                     /locus_tag="JXV47_003390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1489330.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            4533..4835
                     /locus_tag="JXV47_003391"
                     /pseudo
     CDS             4533..4835
                     /locus_tag="JXV47_003391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1576 a          787 c          844 g         1666 t
ORIGIN      
        1 tctcagcaaa ttgttgaaga acatttgcgt aaataatctt tcttaacaag taaacctaaa
       61 ttagtaaaga agcaacagta atctatacta agtagttcag ttttggagta caaaatgaca
      121 aaatgtactt caaaatggac tacttttttc attttaactt acataccaaa ttacatacaa
      181 aatgatttat aaaatgcaat tgaaaatgat aattgaatga aaatttgtga ttttgtggta
      241 ttatgataat ataacttata gaaaaaattg cttattcaac taacgggcag gataatgaga
      301 aaaggttttt tgatagaaat aagaaattag atggtaaatt agttaaaaag gctgtgttat
      361 aaatgaaagt ttctttgatt gctgcgatgg ataagaatag agtgattggc aaagagaatg
      421 acattccttg gaggattccc aaggactggg aatatgttaa aaatactaca aagggacatc
      481 cgataatatt aggtaggaag aaccttgaat caatcggaag agccttacct gacagaagaa
      541 atattattct gacgagagat aaggggttta cctttaatgg ttgtgaaatt gttcattcaa
      601 tagaagatgt ttttgagtta tgtaaaaacg aagaagaaat ttttattttc ggaggagaac
      661 agatttataa tttgtttttc ccttatgttg agaaaatgta catcacaaaa atacatcatg
      721 aattcgaagg agatactttt tttccagaag tgaattatga ggaatggaat gaggtatttg
      781 cccaaaaagg gataaagaat gataaaaatc cgtataacta ctattttcat gtatatgaaa
      841 gaaaaaactt attgagttaa cgggtgcgtt aattgaagaa gaacagtaaa gataaagcac
      901 aagagcttgg gattactcca agctcttttt gtcatttgaa ataaattata tctttccaat
      961 caaattgttt atctgtaatc cctaatcttt gagcaggtgt caaaaccttt ttatccgctg
     1021 atttaaaagg gcgacaaaag ttgtagtaag ttcttagaat tgtaatcgca aattgagcat
     1081 acttcggatt gaagttagcg taaatatagc tcttcttatc accacgagct gttgttaatg
     1141 gtctttcaag agatgatata taacgtctta tctgttgaat aaagctattg gtcgaatggt
     1201 cattaacatt taatagcatc tttgcgattt cgtttggttc cagagcagat aaatccgttc
     1261 tacaatcaac tgaataaaat cctttatcct tagtggctaa tggatgtttg atagggttat
     1321 cggcatattt gcgatatctt tctccatctt tactaatagc ctcttcgtgg aattgatgac
     1381 ttgttagtaa ttcagttaga taatgagatg ccaaagtccg tagaaacttt gttttgaatc
     1441 ctctgatatc tccccaatcg agcagttctg cttttgcttg tccgaattct tttaagcatt
     1501 gttttctgct tttcgtcttg ttaacttggc aaataaaatg atgtgcatcg ctcaacctta
     1561 attctttcgt gaatactcta taaaaggcgt ttctaataga gaagtcatca tcactaatca
     1621 ttcgccattc gtcggcatta accatttgtt taattaacca atagtgagca gttgtagtat
     1681 aaggagcatc aacatttaaa ccatcgacaa atctactcct attagtaatt ttccctaatt
     1741 cgtgaagata agcattccta ttttcgctat cgttagcgga tggttcttgt ggataataag
     1801 accaatctaa cctatcattt ttacgactaa aagtattgag atggtcttct ttgaattttc
     1861 ttgtatcttc atttaattca tccattgaaa tattccaatc ataggcaaca tcagaacgga
     1921 acacatatct tgataagacc tcagcagata caactatata cgtttgcata ttaaggtctt
     1981 caaaccccgt atatttcttt gaaccttgtc ctttcttacg gacgttattt aggtagtagt
     2041 gcatcttgtc cgtattaagc cacatctcgt taaatttctt tgtttgaagg ggttgtgtct
     2101 catatcgttc taaaaactcc aaacaacgcc tatacagcca ctccagctta tgatagtagg
     2161 ttccaactcc aattcctaaa atatcacaag tacgactgac tgaaaccctt ccaacaacca
     2221 tcttagcgaa cattggaaga atggtgttct tttgttggtg ataagtagtg gtttcttctc
     2281 tttttggtag aacattagtg aacttcttac acgccttaca ttgatagcgt tgagatttgc
     2341 ccctactttt cccccttttg taaaattgct tcggctcatt gaatggggtt gattcttctt
     2401 ccgagcagcc ttctttatga aattgataat ctggctcaac atcttggatg ctattgattt
     2461 ctataaggcg tttaatttct tcaacaacag accaattaga taaaggggtt actgtacagt
     2521 tttgcgatac acctctgcca ataggattgt cattgcagta cataccttta tgacctttat
     2581 ctttggaact accagtcatt ttatatcgac ttggtttccc ttttacatct ttgaatttgt
     2641 gctgttcttt cccaaaatta caacaaaacg gattgatgca gtaattatat tgaatgggat
     2701 attcagaacc gttccattta aaagacgttg gcaagaacaa cattttgtta taccttgttg
     2761 caaatcgttt tggagttaat aaatcatatt gtttagccct atcttttaat tcttcgtttg
     2821 aaatcggaat tttaacatct acaatttcat cttccttcgt ggctaatctt ttaagcttgg
     2881 tcattgtcta tcaacccact ctatctttga tacccatttt ttcaacaatc cgcttattac
     2941 ttcgcttgtt ggcaatccat tcaataaact tcttatcgtc taaaatgttc aataagaatt
     3001 catccactgc ttcgctttca gtacgctctg catattcagc gtattgctta actatcaccc
     3061 ttacttgctc tgatatttcc caatccacag acttagcgtt cttatttttt ggctcaagaa
     3121 attgcatagg aaaatgcacc cctttttgct tagtaaattg taaccatttt aacacaccaa
     3181 tttgcattcc tacaataatt atttcacgtt cgcattttta tatacatttt aacttacatt
     3241 ttgtggtgta aattaacaac aaacgttgat ttaacaataa aaaacgagta tcaaattcag
     3301 ttgcaatttg atactcattt aggtttacat tttcactttt tgtactccaa aactgaacta
     3361 cttaaatcta tactgctgcc tctttttttt agtacatgtc cttcatcttc gcaggaagtg
     3421 ccaatatgat tttaagaaag gtaatagaca aaaagtcaaa aagataaaac agagtttctt
     3481 ctttacaaag ggaatgtatg ttcgtataat ggtattgagg tgaaggttat ggagaaaaaa
     3541 tatggaacag tagataagat ccgtactttg caagttagtg ccagaccgtt gatccgtttc
     3601 agtttaaatg gggtcaattg tttgattgct tcccatagtt tgaacttcct agctgaagta
     3661 gacgaaggga tgaagttagt cgttacaggt tattataata atagaaagca atttgttgtg
     3721 agatcctatc atgtgttagg gaaacccaaa attgtggtag aatatgagaa aagtctatac
     3781 ccaagaaaaa aggtccgaca agatgaaaga ataaactaga aaacaagcgg ctgagacaaa
     3841 aatgtcctag ccgcttgttt tggaaagatg gatgcagacg atgggatttg aacccacacg
     3901 agcatacgct cacaagaacc tcaatctata tataactaca tgtatttaag tatttgtgat
     3961 gaatcactaa actttccaaa ctcatttgag ggatattgct taaagattga acagatcaat
     4021 tcgaagccct attagtattc gctcaatggg gggatcagag gccataaaaa gagactagtc
     4081 attactagtc tcaggtagtg gaattgtagg attttaaacg ttcctggaga gtaccggtat
     4141 gtaactcgaa gaggtgatta tcatagtcgt aaaagtaaat tgaagaagcc tcgcctttca
     4201 cacgagaacg tcctggttcg acagttaaac ctaacatttg gatttttgag acaaacgaat
     4261 ctatatcttg ttcgtcaatt ttaaaagcaa tatgattgta tgtctttggc agtttattcg
     4321 acgaattctg cattactgca atccataggt ccttaactaa gaaaaatttt tctggatata
     4381 atgaaaattt ttttgttgac tatcgtagat ttcttttgca tcaaataagg tatttaacaa
     4441 ttaagtattt aaaagataac ttttaagtta tctttaagta atgcttaaag ctatgttata
     4501 ctctattagg aaatataaga aggagtataa aaatgaacaa acataataga aaaataacga
     4561 ataacaaaga actgatcttg ttactaatag ggatttgggg tatcttttta ctctttaata
     4621 tgtatatgcc gactatgaga gcggatgacg tagtttatgc aagtagatta gatgaacttg
     4681 gctatttggg tgcttcgata gaacattata agacatggag ttcaagaatt attatagaac
     4741 tattcttaat gttcttttct aaacacttta tgctatggaa attattaaat tctacgatta
     4801 tgttaggaat tgtagtatta ctttgcaagt atgttgagag tataaaatat tttgtgtaaa
     4861 tgaaaaaatc cat
//
LOCUS       DADGKS010000357         3254 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.guided.182, whole genome shotgun sequence.
ACCESSION   DADGKS010000357 DADGKS010000000
VERSION     DADGKS010000357.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3254
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.guided.182"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..143
                     /locus_tag="JXV47_003392"
     CDS             <1..143
                     /locus_tag="JXV47_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAX1489331.1"
                     /translation="EADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITT
                     FE"
     gene            497..1975
                     /gene="msr"
                     /locus_tag="JXV47_003393"
     CDS             497..1975
                     /gene="msr"
                     /locus_tag="JXV47_003393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAX1489332.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            2022..2468
                     /locus_tag="JXV47_003394"
     CDS             2022..2468
                     /locus_tag="JXV47_003394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAX1489333.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(2667..3182)
                     /locus_tag="JXV47_003395"
     CDS             complement(2667..3182)
                     /locus_tag="JXV47_003395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAX1489334.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
BASE COUNT         1031 a          548 c          676 g          999 t
ORIGIN      
        1 tcgaagcaga tcagttggca gaggcatttg gtttggataa agaccgttat gttccagtta
       61 ttattttatc aataggaaaa gcggtagaag aaggttacga gtctgttcgt ttagcaccag
      121 aaaagatcac tacgttcgaa taaaaggttt tcagttacta ttcagtagct attgcttttt
      181 ttgaatcgtg tgtggtaacc taataaaaaa ggaggtcgga aaaatgactg catcgatgaa
      241 attacgtttc gaacttttga ataacaacta aataaattca aaagacatgt ataaacaaca
      301 atttcatgga tggagtatgt ccattttttc gaacgacagt agaataggtg aaagctatga
      361 cagatttggt gatttagtca tagttatttc gttcagagta ggaaaagatg tgatgcagtt
      421 tttttgcaaa cagatttttc tgctcttttt tagtatcgat aattgttgtt ttacatgaaa
      481 taggagtgta aaacatatgg aaaatttagc agtaaatata acaaatctac aagtcagctt
      541 tggcaaccag ctagaactat ctattgattc tcttcgtgtc tatcagcaag atcgtatagg
      601 gatcatagga gaaaatggtg tcggtaaatc gactttgctc aaactaatag ccggtgaact
      661 ttttcccgat catgggaaaa tccaaacaga gatcaccttc aactacctgc ctcaattaac
      721 ctatctcgct gaagcaaagg acctaaattt ggaattagcc agtcatttcc agttaagact
      781 ggaagaaact tcagagcgga aatggagcgg aggggaagaa cgaaagatcg agttgatacg
      841 tcttctttct tcttatgaac aagggatgct tctagacgag ccaacaaccc atctagatag
      901 aaaaagtatt gatcgactga ttgaagagct tcgttattat tatggtacgc tggtttttgt
      961 tagtcatgat cgctattttc tagatgagct agcatcgaaa atctgggaag taaaagacgg
     1021 agaaatccga gagttttcgg ggaattatag tgcctatctc actcaaaagg aattggagaa
     1081 aaagactcag ctacgagaag cagagtcgat catgaaagag aaaaaacgat tggaaaaatc
     1141 gatccaagaa aagaaaaaac aagcggaaaa gttggaaaaa gtgtccagta aaaagaaaaa
     1201 gcaacaaatc agaccggatc ggttgtcttc ctctaaacaa aaagacagtg tacaaaaagc
     1261 catccaaaag aatgcgaaaa cattagagag aagactccaa aaaataggag aaacaaccaa
     1321 gccgcagcag atgaaacaaa tccgttttcc agtaccaaaa tctcttgaac tccacagccg
     1381 ctatcccatc atgggacaaa atgtccaatt ggaaagaagt gggagaacat tactggtaaa
     1441 tggtgatttt cagttttctt taggtaaaaa aatcgcgatt gtcggtgaaa atggttcagg
     1501 taagacaacc ttattagaac atatccgcaa acaaggagaa ggaatccttc tctctccgaa
     1561 agtaagcttt caagtatatc agcaaaaggg ttatcaaatg acatctgaag aatccatcat
     1621 tcgttttgtc atgagacaaa cagagttttc agaatcgctt gtccgtagtt tgctgaatca
     1681 cttagggttt gctcaggaaa ctttgacgaa accgttatgt acattaagtg ggggagaagc
     1741 gacccgtctg acgattgctt tgctttttac taagccaagt aatgtgttgc tgttagatga
     1801 accgactaat tttattgata tggcaacgat cgaagcttta gagaagctaa tgcaaatata
     1861 tccgggaacg attttgttta cttctcatga ttcttacttt gtcgagcgta cggctgatga
     1921 agtttatgaa ataaaagggc agaaaataaa aaaagtactt acgagaaatt tttaaatgtg
     1981 ctacgatgat tttcgtgaca aatttaaagg agtggtacag attgcctaca aataaaaaag
     2041 aaggaataat ttttacaaca atgatgtgtt ttttgatggt cttggggatg agcgcgtata
     2101 atttatggct gcatcaagat cttcatttat caagtttgtt gattggtcta gtgcctggat
     2161 tcgtggtggc tttcattttg gatgtcttca tcatcggtgt gctggcgaaa aaaattgcct
     2221 ttaaactacc agtaaatcca gaaagcaagg tccaaatgat cttaactatt tcatgcttga
     2281 tggttttagg aatggtgaca tgtatgtctt tattcggtgt gatcatggaa caaggaatac
     2341 ctgatcaatt attctctgct tatatgaatg cttggaaaat gaatgtgatt gccgctttac
     2401 cgttgcagtt gatcatcgtt ggcccgcttt caagaagtgt gctaaaagca attcaaagta
     2461 atgaatgatg gaacactgtt atttgaaaaa aggccttggc atgctttttg tcatagtctc
     2521 ttgaatgcag ttctagaaaa atagtgatcc gaacgatagg ttttggcctg tcgttcggat
     2581 cgctttttct tttccaactg tattgctctt ttattgaaga taatttgctc ttcaatagat
     2641 atttctagaa aggttctgtt tatcccttac tcaaaaaact gctgcatttg ttctcttact
     2701 tgctgacacc attggagttc ctgctgacaa agcataattc tgcgctggat cacaacataa
     2761 cgtccaaatt cttgtttctt gtctagcgag aggtcattca attttttttg atttttttgc
     2821 atgattttgt tcagctgttg ttctctagtg aatagcagtc cagtagctgt tgttttatcg
     2881 agcgtcgaaa aagcatagat ttttgctaga aattcatctt tttgcgtagg agcgggagtt
     2941 tcctctttga tccattcctc tacaagagca cgtccttcat cagtcaagtg gtagatcttt
     3001 ttttgagagt gctcgtcttt gtccaaaacg gtcacataac cctgctggtc taacttggca
     3061 agcgttgtat agatctgact gtgatgggct tcccaaaaaa ttgtgatcag ctgcttcaat
     3121 tcatacccag aacgtggttt ggataaaagc acgcataata atatataggc taaagtattc
     3181 ataaaaatcc tacctctcgt cttattttct ttattatatc acagtaaagt ttccacgttt
     3241 tacatgtgca tatt
//
LOCUS       DADGKS010000358         2772 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.guided.194, whole genome shotgun sequence.
ACCESSION   DADGKS010000358 DADGKS010000000
VERSION     DADGKS010000358.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2772
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.guided.194"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            111..194
                     /locus_tag="JXV47_003396"
     CDS             111..194
                     /locus_tag="JXV47_003396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HAX1489335.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            319..1056
                     /gene="erm(B)"
                     /locus_tag="JXV47_003397"
     CDS             319..1056
                     /gene="erm(B)"
                     /locus_tag="JXV47_003397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAX1489336.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1319..2182)
                     /locus_tag="JXV47_003398"
     CDS             complement(1319..2182)
                     /locus_tag="JXV47_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin zeta"
                     /protein_id="HAX1489337.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(2184..2456)
                     /locus_tag="JXV47_003399"
     CDS             complement(2184..2456)
                     /locus_tag="JXV47_003399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAX1489338.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            complement(2473..2682)
                     /locus_tag="JXV47_003400"
     CDS             complement(2473..2682)
                     /locus_tag="JXV47_003400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HAX1489339.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
BASE COUNT          851 a          488 c          443 g          990 t
ORIGIN      
        1 cttatttgat agtagattta aaactttgca acagaaccaa aattttgtat aataggaatt
       61 gaagttaaat tagatgctaa aaatttgtaa ttaagaagga gggattcgtc atgttggtat
      121 tccaaatgcg taatgtagat aaaacatcta ccgttttgaa acagactaaa aacagtgatt
      181 acgcagataa ataaatacgt tagattaatt cctaccagtg actaatctta tgacttttta
      241 aacagataac taaaattaca aacaaatcgt ttaacttctg tatttattta tagatgtaat
      301 cacttcagga gtgattacat gaacaaaaat ataaaatatt ctcaaaactt tttaacgagt
      361 gaaaaagtac tcaaccaaat aataaaacaa ttgaatttaa aagaaaccga taccgtttac
      421 gaaattggaa caggtaaagg gcatttaacg acgaaactgg ctaaaataag taaacaggta
      481 acgtctattg aattagacag tcatctattc aacttatcgt cagaaaaatt aaaactgaac
      541 actcgtgtca ctttaattca ccaagatatt ctacagtttc aattccctaa caaacagagg
      601 tataaaattg ttgggaatat tccttaccat ttaagcacac aaattattaa aaaagtggtt
      661 tttgaaagcc atgcgtctga catctatctg attgttgaag aaggattcta caagcgtacc
      721 ttggatattc accgaacact agggttgctc ttgcacactc aagtctcgat tcagcaattg
      781 cttaagctgc cagcggaatg ctttcatcct aaaccaaaag taaacagtgt cttaataaaa
      841 cttacccgcc ataccacaga tgttccagat aaatattgga agctatatac gtactttgtt
      901 tcaaaatggg tcaatcgaga atatcgtcaa ctgtttacta aaaatcagtt tcatcaagca
      961 atgaaacacg ccaaagtaaa caatttaagt accgttactt atgagcaagt attgtctatt
     1021 tttaatagtt atctattatt taacgggagg aaataattct atgagtcgct tttgtaaatt
     1081 tggaaagtta cacgttacta aagggaatgt agataaatta ttaggtatag ggcacctcta
     1141 ataactacca attaattcac ctcaaaatga aattagaaaa aaacagcgaa atttttaaat
     1201 ctatttctta tcgatacaaa ttcctcgtag gcgctcggga ccccaacatg aggaaatgtt
     1261 tttataaaaa aagagtagtt accgtttttt ggtaactact cttttccttt tttaaggttt
     1321 aaatacctgg aagtttaggt gttttgggta ttggtggtgt aggtagctgc aagctttcca
     1381 ttttttgttg aattgcttta aattcagggg tttcttggtg ttgattttga accatttttt
     1441 gctctattct ctccaaagtc ggttgaattt ctttccctga tactttacga tttaattctc
     1501 tttctaaggt ctctttcgga ctaatggaag gcgtttctaa gcttgaatag agtttcactc
     1561 cttctctatt gtaaagcctt atatcgctaa ataagcccgt tttatgaagg gtttctaaat
     1621 tggtcggtaa gtttttgaca acaatatcat gcgcttgttt tggtgttgcc ctagctgtca
     1681 ttggatcatc tgcatacatg gtttcatatc gttcaatcgt tcctaagtat gattcaattt
     1741 tcggtactgc catgacgtat atttttgttt cataaccttt agattgaagc attgtggctg
     1801 tttgaatggg aacgtctgtt gttcgtcctg ttccttcaat cactaaatta tagccttgat
     1861 cgcttaaacg gctaataagt gcttctgtca tgcgattcga ataaggggta acgtgtttta
     1921 ctacgtcttt ttcatagagt ttcactaatt cgtcaaaatt tgggtgctgt tgtttaaagg
     1981 tatcattatc aatgacaata acattccctt gtgtttcttc aaaaattgct gatcgcaaac
     2041 tggttttccc tgaccctggt tgcccaccaa gtaaaaaagc ggttggcgat tcaaccgcta
     2101 gtctattttt agttagtcgt tcaacattct tttctaaacg atcttcaaat tgcttttcgg
     2161 tgaagtcagt aatattcgcc atgttaagcc actttctctt tattcaaaat ttgttttgaa
     2221 tattgattca ttgaccgcca atactcatga atagcttgta attcttcaaa tggttgttga
     2281 aataaatcaa cttcttgtgc cacttctaat tgatttaaaa gattcacttc tagtaaacga
     2341 gtatttttag tatctagttc atgattcaaa acataattta atacccgatt ataaacactt
     2401 gccgataact cattaatgat ttcaatttca aatgtttttt catacgtaac tgccatttca
     2461 ttttcactcc ttttaaagtt tgtcaggtaa atatttccgt atatattctt ctaaggcttg
     2521 atccataact tcttttacgt ttccgccatt ctttgctgtt tcgattttta tgatatggtg
     2581 caagtcggca cgaacacgaa ccgtcttatc ccccattata tctttttttg cgctgattgg
     2641 cgtatcattt cgttttgctt tctgtgcgcc taaatttccc acgatcgctc acttctttct
     2701 atttcttctt actatttatt ttatcatcac ctatcacaaa tcacaagtga tttgtgatta
     2761 atcacttgtg at
//
LOCUS       DADGKS010000359         1632 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.guided.230, whole genome shotgun sequence.
ACCESSION   DADGKS010000359 DADGKS010000000
VERSION     DADGKS010000359.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1632
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.guided.230"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            43..1545
                     /gene="lsa"
                     /locus_tag="JXV47_003401"
     CDS             43..1545
                     /gene="lsa"
                     /locus_tag="JXV47_003401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lsa family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAX1489340.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQAFVYFPQQTKDKERLTYYVLNEIMDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEIAKNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKKVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDALTMNSQVSHHKRLLSVENLQLGYENLLFEPVHF
                     TIEPHQRMAISGPNGAGKSSIIHYLLGTFNGKVVGEKSQPKHLTISYVRQNYEDNRGT
                     LAEFAKKNRVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYI
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLEKI"
BASE COUNT          596 a          279 c          352 g          405 t
ORIGIN      
        1 tctgaaaata ggactggtct ttttttacga ggtgatggaa taatgtctaa aatcgaaata
       61 aaaaatctga cattcggcta tgacagccaa ggcacattat tatttgaaca agccaatcta
      121 aactttgaca cacaatggaa actaggactt atcggacgaa acggtcgagg aaagacaact
      181 ttactgaata tcctgcaaaa caaactccct tatcaagggc aagtgatcca tcagcaagcg
      241 tttgtctatt tcccgcagca aacaaaagat aaagagcgtt tgacctatta tgtgttaaat
      301 gagattatgg attttgagat atgggaaatt gaaagagagc tccaactgat gcaaacagat
      361 cctgaaatct tatggagaga attcagcaca ctatcaggag gagagaagac aaaagtccta
      421 ctggcactct tatttgtgga tgacactcat ttcccgttaa tcgatgaacc aacgaatcat
      481 ttggatatct ctggcagaaa acaagtagcg gcttacttga aaaagaaaaa acaaggattc
      541 atcgtggtga gtcatgatcg gggatttatc gatgaagtag tggaccatgt tttagcaatc
      601 gaaaagagcc aactggaact ttatcaaggg aatttctcta tctatgaaga acagaaaaaa
      661 cttcgtgatg aatttgaaat agctaaaaat gaaaaattga aaaaagaagt cagcaggcta
      721 aagaaaacag cagctgaaaa agcagaatgg tctcgttccc gagaagggga caaaacaaag
      781 aaaaaagtcg gattcatcga tacggaatct aggcgagtga ataaaggagc agtaggcgct
      841 gatgctgcac ggacgatgaa acgatctaaa gcaatcgtga atcggatgga aacccagatc
      901 agtgagaaag aaaaattatt aaaagatatc gagtatatcg atgctttgac gatgaatagc
      961 caagtgtctc atcataaacg gctgttaagc gtagaaaatc ttcaattagg gtatgaaaat
     1021 ctgttattcg agccagttca ttttacgatc gaacctcatc agcggatggc aatttcaggt
     1081 cctaacggcg cgggaaagtc atccattatc cattatcttc tggggacatt caacggcaag
     1141 gttgtaggag aaaaatccca gcccaaacat ttgaccatta gttacgtacg ccaaaattat
     1201 gaagacaatc gagggacatt ggcggaattc gcgaagaaaa accgagtaga ctatcaagca
     1261 tttttgaata atctccgaaa gcttgggatg gaaagagatg tttttcataa taaaatcgaa
     1321 cagatgagta tgggacaacg gaaaaaagtg gaattggcta aatctttatc ccaaccagct
     1381 gagctctata tatgggatga accattgaat tatttggatg tcttcaatca agaacaatta
     1441 gaacaactga ttttgaacgt gaaacctgct atgttactag tggaacatga tcaaaccttt
     1501 ctagataaag tatctactga gattatttct cttgagaaaa tctaaacctt gtaatctcaa
     1561 agacaacaag gtatggttaa ggagaacttt gtcaacgaag gagagaatca catgctttat
     1621 gtaacgagac ac
//
LOCUS       DADGKS010000360         1631 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VD1446
            SAMN17922587-rid11630413.guided.231, whole genome shotgun sequence.
ACCESSION   DADGKS010000360 DADGKS010000000
VERSION     DADGKS010000360.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922587
            Sequence Read Archive: SRR13717171
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968304.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968304.1
            Genome Coverage       :: 85x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 21:47:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,402
            CDSs (total)                      :: 3,337
            Genes (coding)                    :: 3,261
            CDSs (with protein)               :: 3,261
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 38 of 76
            Pseudo Genes (incomplete)         :: 37 of 76
            Pseudo Genes (internal stop)      :: 20 of 76
            Pseudo Genes (multiple problems)  :: 14 of 76
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1631
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922587-rid11630413.guided.231"
                     /isolate="VD1446"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-07-02"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            42..1544
                     /locus_tag="JXV47_003402"
     CDS             42..1544
                     /locus_tag="JXV47_003402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HAX1489341.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
BASE COUNT          597 a          287 c          349 g          398 t
ORIGIN      
        1 tctgaaaata ggactggtct ttttttacga ggtgatggaa aatgtctaaa atcgaaataa
       61 aaaatctgac attcggctac gacagccaag gcacattatt atttgaacaa gcaaatctaa
      121 attttgacac acaatggaaa ctaggactta tcggacgaaa cggtcgagga aagacaactt
      181 tactgaatat tctacaaaac aaactacctt atcaagggca agtaatccat cagcaagaat
      241 ttgcctattt cccgcaacag acaaaagata aagaacgttt aacctattac gtgttaaatg
      301 atattacgga ttttgagata tgggaaatcg aaagagagct ccaattgatg caaacagatc
      361 ctgaaatctt atggagagaa ttcagcacac tatcgggggg agagaagaca aaagtcctac
      421 tggcactttt atttgtggat gacactcatt tcccgttaat cgatgaacca acgaatcatt
      481 tggatatctc tggtagaaaa caagtagcgg cttatttgaa aaagaaaaaa caaggcttca
      541 tcgtggtcag ccatgaccgg ggatttatcg atgaagtagt ggaccatgtt ttagcaatcg
      601 aaaaaagtca actggaactt tatcaaggga atttctctat ctatgaagaa cagaaaaaac
      661 ttcgtgatga atttgaaatg gctcaaaatg aaaaattgaa aaaagaagtc agtaggctaa
      721 agaaaacagc agctgaaaaa gccgaatggt ctcgttcccg agaaggagat aaaacaaaga
      781 aacaagtcgg attcatcgat actgaatcta gacgagtgaa taaaggagca gtgggtgctg
      841 atgctgcacg gacgatgaaa cgatccaaag caatcgtgaa tcggatggag acccagatca
      901 gcgagaaaga aaaactatta aaagatatcg aatatatcga ttctttgacg atgaatagcc
      961 aagcgtctca ccataagcga cttttaagcg tagaagatct tcaattaggg tatgaaaatc
     1021 tgttattcga gccaattcat tttacaatcg agcctcatca gcgggtggcg atttcaggtc
     1081 ctaacggtgc aggaaagtca tccattatcc attatcttct gggggcattc aacggcaagg
     1141 ttataggaga aaaataccag ccaaaacatc tgagcattag ttatgcaagc caaaattatg
     1201 aagacaatcg aggaacgttg gcggaatttg cagagaaaaa ccaagtagac taccaagcat
     1261 ttttgaacaa cctccgaaag cttgggatgg aaagagatgt ttttcataac aagatcgagc
     1321 agatgagtat gggccaacgg aaaaaagtgg aattggctaa atctttatca cagccagctg
     1381 aactatatac atgggatgaa ccattgaatt atttggatgt cttcaatcaa gaacaattag
     1441 aacaactgat cttgaacgtg aaacctgcca tgttactagt ggaacatgat caaaccttcc
     1501 tggataaagt atctactgag attatttctc ttgagagaat ctaacccttg taatctcaag
     1561 aacaacaagg tatggttaag gggaactttg ccaacgaagg agagaatcac atgctttatg
     1621 taacgagaca c
//
